-- dump date   	20140619_090827
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
431946000001	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
431946000002	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
431946000003	putative catalytic residues [active]
431946000004	putative nucleotide binding site [chemical binding]; other site
431946000005	putative aspartate binding site [chemical binding]; other site
431946000006	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
431946000007	dimer interface [polypeptide binding]; other site
431946000008	putative threonine allosteric regulatory site; other site
431946000009	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
431946000010	putative threonine allosteric regulatory site; other site
431946000011	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
431946000012	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
431946000013	homoserine kinase; Region: thrB; TIGR00191
431946000014	Protein of unknown function; Region: YhfT; pfam10797
431946000015	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
431946000016	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
431946000017	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
431946000018	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946000019	catalytic residue [active]
431946000020	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
431946000021	hypothetical protein; Validated; Region: PRK02101
431946000022	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
431946000023	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
431946000024	transaldolase-like protein; Provisional; Region: PTZ00411
431946000025	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
431946000026	active site
431946000027	dimer interface [polypeptide binding]; other site
431946000028	catalytic residue [active]
431946000029	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
431946000030	MPT binding site; other site
431946000031	trimer interface [polypeptide binding]; other site
431946000032	hypothetical protein; Provisional; Region: PRK10659
431946000033	hypothetical protein; Provisional; Region: PRK10236
431946000034	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
431946000035	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
431946000036	hypothetical protein; Provisional; Region: PRK10154
431946000037	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
431946000038	Nucleotide-binding domain of human HSPA9, Escherichia coli DnaK, and similar proteins; Region: HSPA9-like_NBD; cd11733
431946000039	nucleotide binding site [chemical binding]; other site
431946000040	NEF interaction site [polypeptide binding]; other site
431946000041	SBD interface [polypeptide binding]; other site
431946000042	chaperone protein DnaJ; Provisional; Region: PRK10767
431946000043	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
431946000044	HSP70 interaction site [polypeptide binding]; other site
431946000045	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
431946000046	substrate binding site [polypeptide binding]; other site
431946000047	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
431946000048	Zn binding sites [ion binding]; other site
431946000049	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
431946000050	dimer interface [polypeptide binding]; other site
431946000051	Hok/gef family; Region: HOK_GEF; pfam01848
431946000052	Nucleoside-specific channel-forming protein, Tsx; Region: Channel_Tsx; pfam03502
431946000053	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
431946000054	Sulfatase; Region: Sulfatase; pfam00884
431946000055	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
431946000056	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
431946000057	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946000058	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
431946000059	putative dimerization interface [polypeptide binding]; other site
431946000060	putative alpha-glucosidase; Provisional; Region: PRK10658
431946000061	XylS is a glycosyl hydrolase family 31 (GH31) alpha-xylosidase found in prokaryotes, eukaryotes, and archaea, that catalyzes the release of alpha-xylose from the non-reducing terminal side of the alpha-xyloside substrate. XylS has been characterized in...; Region: GH31_xylosidase_XylS; cd06591
431946000062	putative active site [active]
431946000063	putative catalytic site [active]
431946000064	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
431946000065	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
431946000066	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
431946000067	Protein of unknown function (DUF2575); Region: DUF2575; pfam10837
431946000068	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
431946000069	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
431946000070	active site
431946000071	Riboflavin kinase; Region: Flavokinase; smart00904
431946000072	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
431946000073	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
431946000074	HIGH motif; other site
431946000075	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
431946000076	active site
431946000077	KMSKS motif; other site
431946000078	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
431946000079	tRNA binding surface [nucleotide binding]; other site
431946000080	anticodon binding site; other site
431946000081	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
431946000082	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
431946000083	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
431946000084	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
431946000085	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
431946000086	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
431946000087	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
431946000088	active site
431946000089	tetramer interface [polypeptide binding]; other site
431946000090	Protein of unknown function (DUF805); Region: DUF805; pfam05656
431946000091	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
431946000092	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
431946000093	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
431946000094	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
431946000095	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
431946000096	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
431946000097	catalytic site [active]
431946000098	subunit interface [polypeptide binding]; other site
431946000099	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
431946000100	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
431946000101	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
431946000102	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
431946000103	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
431946000104	ATP-grasp domain; Region: ATP-grasp_4; cl17255
431946000105	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
431946000106	IMP binding site; other site
431946000107	dimer interface [polypeptide binding]; other site
431946000108	interdomain contacts; other site
431946000109	partial ornithine binding site; other site
431946000110	DNA-binding transcriptional activator CaiF; Provisional; Region: PRK11476
431946000111	carnitine operon protein CaiE; Provisional; Region: PRK13627
431946000112	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
431946000113	putative trimer interface [polypeptide binding]; other site
431946000114	putative metal binding site [ion binding]; other site
431946000115	carnitinyl-CoA dehydratase; Provisional; Region: PRK03580
431946000116	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
431946000117	substrate binding site [chemical binding]; other site
431946000118	oxyanion hole (OAH) forming residues; other site
431946000119	trimer interface [polypeptide binding]; other site
431946000120	putative crotonobetaine/carnitine-CoA ligase; Validated; Region: caiC; PRK08008
431946000121	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_DitJ_like; cd05934
431946000122	acyl-activating enzyme (AAE) consensus motif; other site
431946000123	putative AMP binding site [chemical binding]; other site
431946000124	putative active site [active]
431946000125	putative CoA binding site [chemical binding]; other site
431946000126	crotonobetainyl-CoA:carnitine CoA-transferase; Provisional; Region: PRK03525
431946000127	CoA-transferase family III; Region: CoA_transf_3; pfam02515
431946000128	crotonobetainyl-CoA dehydrogenase; Validated; Region: PRK03354
431946000129	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
431946000130	active site
431946000131	L-carnitine/gamma-butyrobetaine antiporter; Provisional; Region: PRK03356
431946000132	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
431946000133	Ligand binding site [chemical binding]; other site
431946000134	Electron transfer flavoprotein domain; Region: ETF; pfam01012
431946000135	putative electron transfer flavoprotein FixB; Provisional; Region: fixB; PRK03363
431946000136	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF; cd01985
431946000137	Ligand binding site [chemical binding]; other site
431946000138	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
431946000139	putative oxidoreductase FixC; Provisional; Region: PRK10157
431946000140	ferredoxin-like protein FixX; Provisional; Region: PRK15449
431946000141	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946000142	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
431946000143	putative substrate translocation pore; other site
431946000144	glutathione-regulated potassium-efflux system ancillary protein KefF; Provisional; Region: PRK00871
431946000145	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
431946000146	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
431946000147	TrkA-N domain; Region: TrkA_N; pfam02254
431946000148	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
431946000149	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
431946000150	folate binding site [chemical binding]; other site
431946000151	NADP+ binding site [chemical binding]; other site
431946000152	Post-segregation antitoxin CcdA; Region: CcdA; pfam07362
431946000153	CcdB protein; Region: CcdB; pfam01845
431946000154	bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Region: apaH; TIGR00668
431946000155	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
431946000156	active site
431946000157	metal binding site [ion binding]; metal-binding site
431946000158	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
431946000159	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
431946000160	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
431946000161	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
431946000162	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
431946000163	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
431946000164	SurA N-terminal domain; Region: SurA_N; pfam09312
431946000165	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
431946000166	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
431946000167	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
431946000168	OstA-like protein; Region: OstA; pfam03968
431946000169	Organic solvent tolerance protein; Region: OstA_C; pfam04453
431946000170	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
431946000171	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
431946000172	putative metal binding site [ion binding]; other site
431946000173	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
431946000174	HSP70 interaction site [polypeptide binding]; other site
431946000175	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
431946000176	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
431946000177	active site
431946000178	ATP-dependent helicase HepA; Validated; Region: PRK04914
431946000179	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
431946000180	ATP binding site [chemical binding]; other site
431946000181	putative Mg++ binding site [ion binding]; other site
431946000182	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
431946000183	nucleotide binding region [chemical binding]; other site
431946000184	ATP-binding site [chemical binding]; other site
431946000185	DNA polymerase II; Reviewed; Region: PRK05762
431946000186	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
431946000187	active site
431946000188	catalytic site [active]
431946000189	substrate binding site [chemical binding]; other site
431946000190	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
431946000191	active site
431946000192	metal-binding site
431946000193	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
431946000194	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
431946000195	intersubunit interface [polypeptide binding]; other site
431946000196	active site
431946000197	Zn2+ binding site [ion binding]; other site
431946000198	L-arabinose isomerase; Provisional; Region: PRK02929
431946000199	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
431946000200	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
431946000201	trimer interface [polypeptide binding]; other site
431946000202	putative substrate binding site [chemical binding]; other site
431946000203	putative metal binding site [ion binding]; other site
431946000204	ribulokinase; Provisional; Region: PRK04123
431946000205	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
431946000206	N- and C-terminal domain interface [polypeptide binding]; other site
431946000207	active site
431946000208	MgATP binding site [chemical binding]; other site
431946000209	catalytic site [active]
431946000210	metal binding site [ion binding]; metal-binding site
431946000211	carbohydrate binding site [chemical binding]; other site
431946000212	homodimer interface [polypeptide binding]; other site
431946000213	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
431946000214	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
431946000215	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946000216	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946000217	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
431946000218	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
431946000219	putative DNA binding site [nucleotide binding]; other site
431946000220	putative Zn2+ binding site [ion binding]; other site
431946000221	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
431946000222	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
431946000223	substrate binding site [chemical binding]; other site
431946000224	dimer interface [polypeptide binding]; other site
431946000225	ATP binding site [chemical binding]; other site
431946000226	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
431946000227	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
431946000228	inhibitor site; inhibition site
431946000229	active site
431946000230	dimer interface [polypeptide binding]; other site
431946000231	catalytic residue [active]
431946000232	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3181
431946000233	Tripartite tricarboxylate transporter TctA family; Region: TctA; pfam01970
431946000234	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
431946000235	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
431946000236	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
431946000237	ATP-binding cassette domain of the thiamine transport system; Region: ABC_ThiQ_thiamine_transporter; cd03298
431946000238	Walker A/P-loop; other site
431946000239	ATP binding site [chemical binding]; other site
431946000240	Q-loop/lid; other site
431946000241	ABC transporter signature motif; other site
431946000242	Walker B; other site
431946000243	D-loop; other site
431946000244	H-loop/switch region; other site
431946000245	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
431946000246	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946000247	dimer interface [polypeptide binding]; other site
431946000248	conserved gate region; other site
431946000249	putative PBP binding loops; other site
431946000250	ABC-ATPase subunit interface; other site
431946000251	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946000252	dimer interface [polypeptide binding]; other site
431946000253	conserved gate region; other site
431946000254	putative PBP binding loops; other site
431946000255	ABC-ATPase subunit interface; other site
431946000256	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
431946000257	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
431946000258	transcriptional regulator SgrR; Provisional; Region: PRK13626
431946000259	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
431946000260	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
431946000261	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
431946000262	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
431946000263	substrate binding site [chemical binding]; other site
431946000264	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
431946000265	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
431946000266	substrate binding site [chemical binding]; other site
431946000267	ligand binding site [chemical binding]; other site
431946000268	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
431946000269	tartrate dehydrogenase; Region: TTC; TIGR02089
431946000270	2-isopropylmalate synthase; Validated; Region: PRK00915
431946000271	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
431946000272	active site
431946000273	catalytic residues [active]
431946000274	metal binding site [ion binding]; metal-binding site
431946000275	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
431946000276	leu operon leader peptide; Provisional; Region: PRK09925
431946000277	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
431946000278	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946000279	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
431946000280	putative substrate binding pocket [chemical binding]; other site
431946000281	putative dimerization interface [polypeptide binding]; other site
431946000282	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
431946000283	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
431946000284	PYR/PP interface [polypeptide binding]; other site
431946000285	dimer interface [polypeptide binding]; other site
431946000286	TPP binding site [chemical binding]; other site
431946000287	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
431946000288	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
431946000289	TPP-binding site [chemical binding]; other site
431946000290	dimer interface [polypeptide binding]; other site
431946000291	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
431946000292	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
431946000293	putative valine binding site [chemical binding]; other site
431946000294	dimer interface [polypeptide binding]; other site
431946000295	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
431946000296	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
431946000297	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
431946000298	DNA binding site [nucleotide binding]
431946000299	domain linker motif; other site
431946000300	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
431946000301	dimerization interface [polypeptide binding]; other site
431946000302	ligand binding site [chemical binding]; other site
431946000303	mraZ protein; Region: TIGR00242
431946000304	MraZ protein; Region: MraZ; pfam02381
431946000305	MraZ protein; Region: MraZ; pfam02381
431946000306	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
431946000307	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
431946000308	cell division protein FtsL; Provisional; Region: PRK10772
431946000309	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
431946000310	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
431946000311	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
431946000312	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
431946000313	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
431946000314	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
431946000315	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
431946000316	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
431946000317	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
431946000318	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
431946000319	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
431946000320	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
431946000321	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
431946000322	Mg++ binding site [ion binding]; other site
431946000323	putative catalytic motif [active]
431946000324	putative substrate binding site [chemical binding]; other site
431946000325	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
431946000326	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
431946000327	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
431946000328	cell division protein FtsW; Provisional; Region: PRK10774
431946000329	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
431946000330	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
431946000331	active site
431946000332	homodimer interface [polypeptide binding]; other site
431946000333	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
431946000334	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
431946000335	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
431946000336	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
431946000337	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
431946000338	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
431946000339	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
431946000340	cell division protein FtsQ; Provisional; Region: PRK10775
431946000341	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
431946000342	Cell division protein FtsQ; Region: FtsQ; pfam03799
431946000343	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
431946000344	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
431946000345	Cell division protein FtsA; Region: FtsA; pfam14450
431946000346	cell division protein FtsZ; Validated; Region: PRK09330
431946000347	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
431946000348	nucleotide binding site [chemical binding]; other site
431946000349	SulA interaction site; other site
431946000350	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
431946000351	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
431946000352	SecA regulator SecM; Provisional; Region: PRK02943
431946000353	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
431946000354	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
431946000355	SEC-C motif; Region: SEC-C; pfam02810
431946000356	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
431946000357	active site
431946000358	8-oxo-dGMP binding site [chemical binding]; other site
431946000359	nudix motif; other site
431946000360	metal binding site [ion binding]; metal-binding site
431946000361	DNA gyrase inhibitor; Reviewed; Region: PRK00418
431946000362	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4582
431946000363	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
431946000364	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
431946000365	CoA-binding site [chemical binding]; other site
431946000366	ATP-binding [chemical binding]; other site
431946000367	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
431946000368	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
431946000369	active site
431946000370	type IV pilin biogenesis protein; Provisional; Region: PRK10573
431946000371	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
431946000372	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
431946000373	hypothetical protein; Provisional; Region: PRK10436
431946000374	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
431946000375	Walker A motif; other site
431946000376	ATP binding site [chemical binding]; other site
431946000377	Walker B motif; other site
431946000378	putative major pilin subunit; Provisional; Region: PRK10574
431946000379	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
431946000380	Pilin (bacterial filament); Region: Pilin; pfam00114
431946000381	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
431946000382	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
431946000383	dimerization interface [polypeptide binding]; other site
431946000384	active site
431946000385	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
431946000386	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
431946000387	amidase catalytic site [active]
431946000388	Zn binding residues [ion binding]; other site
431946000389	substrate binding site [chemical binding]; other site
431946000390	regulatory protein AmpE; Provisional; Region: PRK10987
431946000391	aromatic amino acid transporter; Provisional; Region: PRK10238
431946000392	Protein of unknown function (DUF796); Region: DUF796; cl01226
431946000393	S-type Pyocin; Region: Pyocin_S; pfam06958
431946000394	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
431946000395	active site
431946000396	Colicin immunity protein / pyocin immunity protein; Region: Colicin_Pyocin; pfam01320
431946000397	Colicin immunity protein / pyocin immunity protein; Region: Colicin_Pyocin; pfam01320
431946000398	Colicin immunity protein / pyocin immunity protein; Region: Colicin_Pyocin; pfam01320
431946000399	Colicin immunity protein / pyocin immunity protein; Region: Colicin_Pyocin; pfam01320
431946000400	Transcriptional regulators [Transcription]; Region: FadR; COG2186
431946000401	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
431946000402	DNA-binding site [nucleotide binding]; DNA binding site
431946000403	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
431946000404	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
431946000405	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
431946000406	dimer interface [polypeptide binding]; other site
431946000407	TPP-binding site [chemical binding]; other site
431946000408	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
431946000409	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
431946000410	E3 interaction surface; other site
431946000411	lipoyl attachment site [posttranslational modification]; other site
431946000412	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
431946000413	E3 interaction surface; other site
431946000414	lipoyl attachment site [posttranslational modification]; other site
431946000415	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
431946000416	E3 interaction surface; other site
431946000417	lipoyl attachment site [posttranslational modification]; other site
431946000418	e3 binding domain; Region: E3_binding; pfam02817
431946000419	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
431946000420	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
431946000421	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
431946000422	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
431946000423	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
431946000424	Protein of unknown function (DUF3300); Region: DUF3300; pfam11737
431946000425	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
431946000426	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
431946000427	substrate binding site [chemical binding]; other site
431946000428	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
431946000429	substrate binding site [chemical binding]; other site
431946000430	ligand binding site [chemical binding]; other site
431946000431	hypothetical protein; Provisional; Region: PRK05248
431946000432	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
431946000433	spermidine synthase; Provisional; Region: PRK00811
431946000434	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946000435	S-adenosylmethionine binding site [chemical binding]; other site
431946000436	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
431946000437	multicopper oxidase; Provisional; Region: PRK10965
431946000438	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
431946000439	Multicopper oxidase; Region: Cu-oxidase; pfam00394
431946000440	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
431946000441	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
431946000442	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
431946000443	Trp docking motif [polypeptide binding]; other site
431946000444	putative active site [active]
431946000445	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
431946000446	active site
431946000447	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
431946000448	active site clefts [active]
431946000449	zinc binding site [ion binding]; other site
431946000450	dimer interface [polypeptide binding]; other site
431946000451	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
431946000452	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
431946000453	Walker A/P-loop; other site
431946000454	ATP binding site [chemical binding]; other site
431946000455	Q-loop/lid; other site
431946000456	ABC transporter signature motif; other site
431946000457	Walker B; other site
431946000458	D-loop; other site
431946000459	H-loop/switch region; other site
431946000460	inner membrane transport permease; Provisional; Region: PRK15066
431946000461	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
431946000462	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
431946000463	active pocket/dimerization site; other site
431946000464	active site
431946000465	phosphorylation site [posttranslational modification]
431946000466	Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins; Region: CE4_yadE_5s; cd10966
431946000467	putative active site [active]
431946000468	putative metal binding site [ion binding]; other site
431946000469	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
431946000470	tetramerization interface [polypeptide binding]; other site
431946000471	active site
431946000472	Uncharacterized conserved protein [Function unknown]; Region: COG5464
431946000473	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
431946000474	pantoate--beta-alanine ligase; Region: panC; TIGR00018
431946000475	Pantoate-beta-alanine ligase; Region: PanC; cd00560
431946000476	active site
431946000477	ATP-binding site [chemical binding]; other site
431946000478	pantoate-binding site; other site
431946000479	HXXH motif; other site
431946000480	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
431946000481	oligomerization interface [polypeptide binding]; other site
431946000482	active site
431946000483	metal binding site [ion binding]; metal-binding site
431946000484	putative fimbrial-like adhesin protein; Provisional; Region: PRK09723
431946000485	putative fimbrial protein StaF; Provisional; Region: PRK15262
431946000486	putative fimbrial protein StaE; Provisional; Region: PRK15263
431946000487	Fimbrial protein; Region: Fimbrial; cl01416
431946000488	putative fimbrial outer membrane usher protein; Provisional; Region: PRK09828
431946000489	PapC N-terminal domain; Region: PapC_N; pfam13954
431946000490	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
431946000491	PapC C-terminal domain; Region: PapC_C; pfam13953
431946000492	putative chaperone protein EcpD; Provisional; Region: PRK09926
431946000493	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
431946000494	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
431946000495	Fimbrial protein; Region: Fimbrial; cl01416
431946000496	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
431946000497	catalytic center binding site [active]
431946000498	ATP binding site [chemical binding]; other site
431946000499	poly(A) polymerase I; Provisional; Region: pcnB; PRK11623
431946000500	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
431946000501	active site
431946000502	NTP binding site [chemical binding]; other site
431946000503	metal binding triad [ion binding]; metal-binding site
431946000504	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
431946000505	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
431946000506	Glutamyl- and glutaminyl-tRNA synthetases [Translation, ribosomal structure and biogenesis]; Region: GlnS; COG0008
431946000507	glutamyl-queuosine tRNA(Asp) synthetase; Region: queuosine_YadB; TIGR03838
431946000508	active site
431946000509	nucleotide binding site [chemical binding]; other site
431946000510	HIGH motif; other site
431946000511	KMSKS motif; other site
431946000512	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
431946000513	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
431946000514	2'-5' RNA ligase; Provisional; Region: PRK15124
431946000515	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
431946000516	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
431946000517	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
431946000518	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
431946000519	ATP binding site [chemical binding]; other site
431946000520	putative Mg++ binding site [ion binding]; other site
431946000521	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
431946000522	nucleotide binding region [chemical binding]; other site
431946000523	ATP-binding site [chemical binding]; other site
431946000524	Helicase associated domain (HA2) Add an annotation; Region: HA2; smart00847
431946000525	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
431946000526	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
431946000527	Transglycosylase; Region: Transgly; pfam00912
431946000528	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
431946000529	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
431946000530	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
431946000531	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
431946000532	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
431946000533	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
431946000534	PapC N-terminal domain; Region: PapC_N; pfam13954
431946000535	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
431946000536	PapC C-terminal domain; Region: PapC_C; pfam13953
431946000537	Fimbrial protein; Region: Fimbrial; pfam00419
431946000538	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
431946000539	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
431946000540	N-terminal plug; other site
431946000541	ligand-binding site [chemical binding]; other site
431946000542	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
431946000543	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
431946000544	Walker A/P-loop; other site
431946000545	ATP binding site [chemical binding]; other site
431946000546	Q-loop/lid; other site
431946000547	ABC transporter signature motif; other site
431946000548	Walker B; other site
431946000549	D-loop; other site
431946000550	H-loop/switch region; other site
431946000551	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
431946000552	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
431946000553	siderophore binding site; other site
431946000554	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
431946000555	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
431946000556	ABC-ATPase subunit  interface; other site
431946000557	dimer interface [polypeptide binding]; other site
431946000558	putative PBP binding regions; other site
431946000559	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
431946000560	ABC-ATPase subunit  interface; other site
431946000561	dimer interface [polypeptide binding]; other site
431946000562	putative PBP binding regions; other site
431946000563	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
431946000564	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
431946000565	inhibitor-cofactor binding pocket; inhibition site
431946000566	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946000567	catalytic residue [active]
431946000568	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
431946000569	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
431946000570	Cl- selectivity filter; other site
431946000571	Cl- binding residues [ion binding]; other site
431946000572	pore gating glutamate residue; other site
431946000573	dimer interface [polypeptide binding]; other site
431946000574	H+/Cl- coupling transport residue; other site
431946000575	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
431946000576	hypothetical protein; Provisional; Region: PRK10578
431946000577	UPF0126 domain; Region: UPF0126; pfam03458
431946000578	UPF0126 domain; Region: UPF0126; pfam03458
431946000579	vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379
431946000580	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
431946000581	cobalamin binding residues [chemical binding]; other site
431946000582	putative BtuC binding residues; other site
431946000583	dimer interface [polypeptide binding]; other site
431946000584	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
431946000585	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
431946000586	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
431946000587	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
431946000588	Zn2+ binding site [ion binding]; other site
431946000589	Mg2+ binding site [ion binding]; other site
431946000590	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
431946000591	serine endoprotease; Provisional; Region: PRK10942
431946000592	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
431946000593	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
431946000594	protein binding site [polypeptide binding]; other site
431946000595	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
431946000596	carbohydrate diacid transcriptional activator CdaR; Provisional; Region: PRK11477
431946000597	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
431946000598	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
431946000599	hypothetical protein; Provisional; Region: PRK13677
431946000600	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
431946000601	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
431946000602	trimer interface [polypeptide binding]; other site
431946000603	active site
431946000604	substrate binding site [chemical binding]; other site
431946000605	CoA binding site [chemical binding]; other site
431946000606	PII uridylyl-transferase; Provisional; Region: PRK05007
431946000607	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
431946000608	metal binding triad; other site
431946000609	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
431946000610	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
431946000611	Zn2+ binding site [ion binding]; other site
431946000612	Mg2+ binding site [ion binding]; other site
431946000613	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
431946000614	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
431946000615	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
431946000616	active site
431946000617	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
431946000618	rRNA interaction site [nucleotide binding]; other site
431946000619	S8 interaction site; other site
431946000620	putative laminin-1 binding site; other site
431946000621	elongation factor Ts; Provisional; Region: tsf; PRK09377
431946000622	UBA/TS-N domain; Region: UBA; pfam00627
431946000623	Elongation factor TS; Region: EF_TS; pfam00889
431946000624	Elongation factor TS; Region: EF_TS; pfam00889
431946000625	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
431946000626	putative nucleotide binding site [chemical binding]; other site
431946000627	uridine monophosphate binding site [chemical binding]; other site
431946000628	homohexameric interface [polypeptide binding]; other site
431946000629	ribosome recycling factor; Reviewed; Region: frr; PRK00083
431946000630	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
431946000631	hinge region; other site
431946000632	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
431946000633	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
431946000634	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
431946000635	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
431946000636	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
431946000637	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
431946000638	catalytic residue [active]
431946000639	putative FPP diphosphate  binding site; other site
431946000640	putative FPP binding hydrophobic cleft; other site
431946000641	dimer interface [polypeptide binding]; other site
431946000642	putative IPP diphosphate binding site; other site
431946000643	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
431946000644	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
431946000645	zinc metallopeptidase RseP; Provisional; Region: PRK10779
431946000646	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
431946000647	active site
431946000648	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
431946000649	protein binding site [polypeptide binding]; other site
431946000650	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
431946000651	putative substrate binding region [chemical binding]; other site
431946000652	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
431946000653	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
431946000654	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
431946000655	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
431946000656	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
431946000657	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
431946000658	Surface antigen; Region: Bac_surface_Ag; pfam01103
431946000659	periplasmic chaperone; Provisional; Region: PRK10780
431946000660	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
431946000661	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
431946000662	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
431946000663	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
431946000664	trimer interface [polypeptide binding]; other site
431946000665	active site
431946000666	UDP-GlcNAc binding site [chemical binding]; other site
431946000667	lipid binding site [chemical binding]; lipid-binding site
431946000668	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
431946000669	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
431946000670	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
431946000671	active site
431946000672	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
431946000673	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
431946000674	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
431946000675	RNA/DNA hybrid binding site [nucleotide binding]; other site
431946000676	active site
431946000677	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
431946000678	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
431946000679	putative active site [active]
431946000680	putative PHP Thumb interface [polypeptide binding]; other site
431946000681	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
431946000682	generic binding surface II; other site
431946000683	generic binding surface I; other site
431946000684	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
431946000685	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
431946000686	lysine decarboxylase LdcC; Provisional; Region: PRK15399
431946000687	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
431946000688	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
431946000689	homodimer interface [polypeptide binding]; other site
431946000690	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946000691	catalytic residue [active]
431946000692	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
431946000693	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
431946000694	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
431946000695	putative metal binding site [ion binding]; other site
431946000696	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
431946000697	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
431946000698	Ligand Binding Site [chemical binding]; other site
431946000699	TilS substrate binding domain; Region: TilS; pfam09179
431946000700	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
431946000701	Rho-binding antiterminator; Provisional; Region: PRK11625
431946000702	hypothetical protein; Provisional; Region: PRK04964
431946000703	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
431946000704	hypothetical protein; Provisional; Region: PRK09256
431946000705	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
431946000706	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
431946000707	NlpE N-terminal domain; Region: NlpE; pfam04170
431946000708	hypothetical protein; Provisional; Region: PRK11479
431946000709	Orthopoxvirus protein of unknown function (DUF830); Region: DUF830; cl13998
431946000710	prolyl-tRNA synthetase; Provisional; Region: PRK09194
431946000711	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
431946000712	dimer interface [polypeptide binding]; other site
431946000713	motif 1; other site
431946000714	active site
431946000715	motif 2; other site
431946000716	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
431946000717	putative deacylase active site [active]
431946000718	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
431946000719	active site
431946000720	motif 3; other site
431946000721	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
431946000722	anticodon binding site; other site
431946000723	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
431946000724	homodimer interaction site [polypeptide binding]; other site
431946000725	cofactor binding site; other site
431946000726	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
431946000727	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
431946000728	lipoprotein, YaeC family; Region: TIGR00363
431946000729	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946000730	dimer interface [polypeptide binding]; other site
431946000731	conserved gate region; other site
431946000732	ABC-ATPase subunit interface; other site
431946000733	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
431946000734	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
431946000735	Walker A/P-loop; other site
431946000736	ATP binding site [chemical binding]; other site
431946000737	Q-loop/lid; other site
431946000738	ABC transporter signature motif; other site
431946000739	Walker B; other site
431946000740	D-loop; other site
431946000741	H-loop/switch region; other site
431946000742	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
431946000743	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
431946000744	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
431946000745	active site
431946000746	motif I; other site
431946000747	motif II; other site
431946000748	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
431946000749	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
431946000750	active site
431946000751	catalytic tetrad [active]
431946000752	Transcriptional regulator [Transcription]; Region: LysR; COG0583
431946000753	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946000754	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA; cd08478
431946000755	putative effector binding pocket; other site
431946000756	dimerization interface [polypeptide binding]; other site
431946000757	hypothetical protein; Provisional; Region: PRK05421
431946000758	putative catalytic site [active]
431946000759	putative metal binding site [ion binding]; other site
431946000760	putative phosphate binding site [ion binding]; other site
431946000761	putative catalytic site [active]
431946000762	putative phosphate binding site [ion binding]; other site
431946000763	putative metal binding site [ion binding]; other site
431946000764	Methyltransferase domain; Region: Methyltransf_23; pfam13489
431946000765	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946000766	S-adenosylmethionine binding site [chemical binding]; other site
431946000767	membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783
431946000768	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
431946000769	N-acetyl-D-glucosamine binding site [chemical binding]; other site
431946000770	catalytic residue [active]
431946000771	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
431946000772	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
431946000773	hydroxyacylglutathione hydrolase; Provisional; Region: PRK10241
431946000774	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946000775	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
431946000776	RNA/DNA hybrid binding site [nucleotide binding]; other site
431946000777	active site
431946000778	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
431946000779	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
431946000780	active site
431946000781	catalytic site [active]
431946000782	substrate binding site [chemical binding]; other site
431946000783	C-N hydrolase family amidase; Provisional; Region: PRK10438
431946000784	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
431946000785	putative active site [active]
431946000786	catalytic triad [active]
431946000787	dimer interface [polypeptide binding]; other site
431946000788	multimer interface [polypeptide binding]; other site
431946000789	C-lysozyme inhibitor; Provisional; Region: PRK09993
431946000790	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
431946000791	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
431946000792	active site
431946000793	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
431946000794	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
431946000795	dimer interface [polypeptide binding]; other site
431946000796	active site
431946000797	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
431946000798	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
431946000799	putative active site [active]
431946000800	putative dimer interface [polypeptide binding]; other site
431946000801	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
431946000802	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
431946000803	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
431946000804	NlpC/P60 family; Region: NLPC_P60; pfam00877
431946000805	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG1943
431946000806	Flagellar biosynthesis pathway, component FlhA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlhA; COG1298
431946000807	FHIPEP family; Region: FHIPEP; pfam00771
431946000808	hypothetical protein; Validated; Region: PRK06778
431946000809	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
431946000810	ligand binding site [chemical binding]; other site
431946000811	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
431946000812	active site
431946000813	DNA polymerase IV; Validated; Region: PRK02406
431946000814	DNA binding site [nucleotide binding]
431946000815	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
431946000816	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
431946000817	Coenzyme A binding pocket [chemical binding]; other site
431946000818	hypothetical protein; Reviewed; Region: PRK09588
431946000819	release factor H-coupled RctB family protein; Region: release_rtcB; TIGR03073
431946000820	peptide chain release factor-like protein; Reviewed; Region: prfH; PRK08179
431946000821	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
431946000822	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
431946000823	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
431946000824	metal binding site [ion binding]; metal-binding site
431946000825	dimer interface [polypeptide binding]; other site
431946000826	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
431946000827	active site
431946000828	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
431946000829	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
431946000830	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
431946000831	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
431946000832	trimer interface [polypeptide binding]; other site
431946000833	eyelet of channel; other site
431946000834	gamma-glutamyl kinase; Provisional; Region: PRK05429
431946000835	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
431946000836	nucleotide binding site [chemical binding]; other site
431946000837	homotetrameric interface [polypeptide binding]; other site
431946000838	putative phosphate binding site [ion binding]; other site
431946000839	putative allosteric binding site; other site
431946000840	PUA domain; Region: PUA; pfam01472
431946000841	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
431946000842	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
431946000843	putative catalytic cysteine [active]
431946000844	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
431946000845	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
431946000846	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
431946000847	Methyltransferase domain; Region: Methyltransf_26; pfam13659
431946000848	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
431946000849	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
431946000850	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
431946000851	ATP binding site [chemical binding]; other site
431946000852	putative Mg++ binding site [ion binding]; other site
431946000853	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
431946000854	Protein of unknwon function (DUF2893); Region: DUF2893; pfam11459
431946000855	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
431946000856	potential frameshift: common BLAST hit: gi|339998310|ref|YP_004729193.1| prophage integrase
431946000857	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
431946000858	active site
431946000859	DNA binding site [nucleotide binding]
431946000860	Int/Topo IB signature motif; other site
431946000861	Domain of unknown function (DUF4102); Region: DUF4102; pfam13356
431946000862	Predicted periplasmic/secreted protein [Function unknown]; Region: COG3477
431946000863	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
431946000864	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
431946000865	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
431946000866	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
431946000867	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
431946000868	DNA binding residues [nucleotide binding]
431946000869	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
431946000870	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
431946000871	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
431946000872	Old yellow enzyme (OYE)-related FMN binding domain, group 4.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as...; Region: OYE_like_4_FMN; cd04735
431946000873	putative active site [active]
431946000874	putative FMN binding site [chemical binding]; other site
431946000875	putative substrate binding site [chemical binding]; other site
431946000876	putative catalytic residue [active]
431946000877	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
431946000878	Transcriptional regulator [Transcription]; Region: LysR; COG0583
431946000879	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946000880	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
431946000881	putative effector binding pocket; other site
431946000882	putative dimerization interface [polypeptide binding]; other site
431946000883	Transcriptional regulator [Transcription]; Region: LysR; COG0583
431946000884	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946000885	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
431946000886	putative effector binding pocket; other site
431946000887	putative dimerization interface [polypeptide binding]; other site
431946000888	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
431946000889	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
431946000890	active site
431946000891	catalytic tetrad [active]
431946000892	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
431946000893	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
431946000894	active site
431946000895	catalytic tetrad [active]
431946000896	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
431946000897	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
431946000898	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
431946000899	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
431946000900	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
431946000901	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
431946000902	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946000903	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
431946000904	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
431946000905	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
431946000906	active site
431946000907	catalytic tetrad [active]
431946000908	Predicted membrane protein [Function unknown]; Region: COG3059
431946000909	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
431946000910	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK08010
431946000911	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
431946000912	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
431946000913	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
431946000914	Cupin; Region: Cupin_6; pfam12852
431946000915	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
431946000916	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946000917	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
431946000918	Cysteine-rich domain; Region: CCG; pfam02754
431946000919	Cysteine-rich domain; Region: CCG; pfam02754
431946000920	iron-sulfur cluster-binding protein; Region: TIGR00273
431946000921	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
431946000922	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
431946000923	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
431946000924	Uncharacterized conserved protein [Function unknown]; Region: COG1556
431946000925	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
431946000926	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cl00185
431946000927	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
431946000928	Autotransporter beta-domain; Region: Autotransporter; pfam03797
431946000929	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
431946000930	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
431946000931	DNA binding residues [nucleotide binding]
431946000932	dimerization interface [polypeptide binding]; other site
431946000933	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
431946000934	active site
431946000935	DNA binding site [nucleotide binding]
431946000936	Int/Topo IB signature motif; other site
431946000937	choline dehydrogenase; Validated; Region: PRK02106
431946000938	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
431946000939	betaine aldehyde dehydrogenase; Provisional; Region: PRK13252
431946000940	NAD+-dependent 4-trimethylaminobutyraldehyde dehydrogenase, ALDH family 9A1; Region: ALDH_F9_TMBADH; cd07090
431946000941	tetrameric interface [polypeptide binding]; other site
431946000942	NAD binding site [chemical binding]; other site
431946000943	catalytic residues [active]
431946000944	transcriptional regulator BetI; Validated; Region: PRK00767
431946000945	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
431946000946	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
431946000947	choline transport protein BetT; Provisional; Region: PRK09928
431946000948	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
431946000949	DNA binding residues [nucleotide binding]
431946000950	dimerization interface [polypeptide binding]; other site
431946000951	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
431946000952	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
431946000953	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946000954	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
431946000955	dimerization interface [polypeptide binding]; other site
431946000956	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
431946000957	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
431946000958	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
431946000959	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
431946000960	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
431946000961	Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Region: SucD; COG0074
431946000962	CoA binding domain; Region: CoA_binding; pfam02629
431946000963	CoA-ligase; Region: Ligase_CoA; pfam00549
431946000964	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
431946000965	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
431946000966	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
431946000967	putative substrate binding site [chemical binding]; other site
431946000968	nucleotide binding site [chemical binding]; other site
431946000969	nucleotide binding site [chemical binding]; other site
431946000970	homodimer interface [polypeptide binding]; other site
431946000971	putative deaminase; Validated; Region: PRK06846
431946000972	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
431946000973	active site
431946000974	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
431946000975	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
431946000976	putative NAD(P) binding site [chemical binding]; other site
431946000977	putative substrate binding site [chemical binding]; other site
431946000978	catalytic Zn binding site [ion binding]; other site
431946000979	structural Zn binding site [ion binding]; other site
431946000980	dimer interface [polypeptide binding]; other site
431946000981	The Resistance to Homoserine/Threonine (RhtB) Family protein; Region: 2A76; TIGR00949
431946000982	hypothetical protein; Provisional; Region: PRK09929
431946000983	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
431946000984	Propionate catabolism activator; Region: PrpR_N; pfam06506
431946000985	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946000986	Walker A motif; other site
431946000987	ATP binding site [chemical binding]; other site
431946000988	Walker B motif; other site
431946000989	arginine finger; other site
431946000990	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
431946000991	Propionate catabolism activator; Region: PrpR_N; pfam06506
431946000992	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
431946000993	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
431946000994	tetramer interface [polypeptide binding]; other site
431946000995	active site
431946000996	Mg2+/Mn2+ binding site [ion binding]; other site
431946000997	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
431946000998	Subgroup of Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS)...; Region: Ec2MCS_like_1; cd06117
431946000999	dimer interface [polypeptide binding]; other site
431946001000	active site
431946001001	citrylCoA binding site [chemical binding]; other site
431946001002	oxalacetate/citrate binding site [chemical binding]; other site
431946001003	coenzyme A binding site [chemical binding]; other site
431946001004	catalytic triad [active]
431946001005	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
431946001006	2-methylcitrate dehydratase; Region: prpD; TIGR02330
431946001007	propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524
431946001008	Propionyl-CoA synthetase (PrpE); Region: PrpE; cd05967
431946001009	acyl-activating enzyme (AAE) consensus motif; other site
431946001010	putative AMP binding site [chemical binding]; other site
431946001011	putative active site [active]
431946001012	putative CoA binding site [chemical binding]; other site
431946001013	nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; Region: SLC-NCS1sbd_CobB-like; cd11484
431946001014	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
431946001015	Na binding site [ion binding]; other site
431946001016	putative substrate binding site [chemical binding]; other site
431946001017	cytosine deaminase; Provisional; Region: PRK09230
431946001018	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
431946001019	active site
431946001020	galactoside O-acetyltransferase; Reviewed; Region: lacA; PRK09527
431946001021	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
431946001022	active site
431946001023	substrate binding site [chemical binding]; other site
431946001024	trimer interface [polypeptide binding]; other site
431946001025	CoA binding site [chemical binding]; other site
431946001026	LacY proton/sugar symporter; Region: LacY_symp; pfam01306
431946001027	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946001028	putative substrate translocation pore; other site
431946001029	beta-D-galactosidase; Reviewed; Region: lacZ; PRK09525
431946001030	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
431946001031	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
431946001032	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
431946001033	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
431946001034	lac repressor; Reviewed; Region: lacI; PRK09526
431946001035	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
431946001036	DNA binding site [nucleotide binding]
431946001037	domain linker motif; other site
431946001038	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
431946001039	ligand binding site [chemical binding]; other site
431946001040	dimerization interface (open form) [polypeptide binding]; other site
431946001041	dimerization interface (closed form) [polypeptide binding]; other site
431946001042	DNA-binding transcriptional activator MhpR; Provisional; Region: PRK09834
431946001043	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
431946001044	Bacterial transcriptional regulator; Region: IclR; pfam01614
431946001045	3-(3-hydroxyphenyl)propionate hydroxylase; Validated; Region: mhpA; PRK06183
431946001046	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
431946001047	Subunit B of the Class III Extradiol ring-cleavage dioxygenase, 2,3-dihydroxyphenylpropionate 1,2-dioxygenase (MhpB), which catalyzes the oxidization and subsequent ring-opening of 2,3-dihydroxyphenylpropionate; Region: MhpB_like; cd07365
431946001048	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
431946001049	putative active site [active]
431946001050	Fe(II) binding site [ion binding]; other site
431946001051	putative dimer interface [polypeptide binding]; other site
431946001052	putative tetramer interface [polypeptide binding]; other site
431946001053	2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; Region: biphenyl_bphD; TIGR03343
431946001054	2-keto-4-pentenoate hydratase; Provisional; Region: mhpD; PRK11342
431946001055	acetaldehyde dehydrogenase; Validated; Region: PRK08300
431946001056	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
431946001057	Prokaryotic acetaldehyde dehydrogenase, dimerisation; Region: AcetDehyd-dimer; pfam09290
431946001058	4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase,; Validated; Region: PRK08195
431946001059	4-hydroxy-2-oxovalerate aldolase, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_HOA; cd07943
431946001060	active site
431946001061	catalytic residues [active]
431946001062	metal binding site [ion binding]; metal-binding site
431946001063	DmpG-like communication domain; Region: DmpG_comm; pfam07836
431946001064	putative 3-hydroxyphenylpropionic transporter MhpT; Provisional; Region: PRK11551
431946001065	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946001066	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946001067	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
431946001068	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
431946001069	S-formylglutathione hydrolase; Region: PLN02442
431946001070	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
431946001071	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
431946001072	substrate binding site [chemical binding]; other site
431946001073	catalytic Zn binding site [ion binding]; other site
431946001074	NAD binding site [chemical binding]; other site
431946001075	structural Zn binding site [ion binding]; other site
431946001076	dimer interface [polypeptide binding]; other site
431946001077	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
431946001078	putative metal binding site [ion binding]; other site
431946001079	putative homodimer interface [polypeptide binding]; other site
431946001080	putative homotetramer interface [polypeptide binding]; other site
431946001081	putative homodimer-homodimer interface [polypeptide binding]; other site
431946001082	putative allosteric switch controlling residues; other site
431946001083	ABC-type taurine transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: TauA; COG4521
431946001084	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
431946001085	substrate binding pocket [chemical binding]; other site
431946001086	membrane-bound complex binding site; other site
431946001087	hinge residues; other site
431946001088	taurine transporter ATP-binding subunit; Provisional; Region: tauB; PRK11248
431946001089	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
431946001090	Walker A/P-loop; other site
431946001091	ATP binding site [chemical binding]; other site
431946001092	Q-loop/lid; other site
431946001093	ABC transporter signature motif; other site
431946001094	Walker B; other site
431946001095	D-loop; other site
431946001096	H-loop/switch region; other site
431946001097	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
431946001098	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946001099	dimer interface [polypeptide binding]; other site
431946001100	conserved gate region; other site
431946001101	putative PBP binding loops; other site
431946001102	ABC-ATPase subunit interface; other site
431946001103	Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175
431946001104	taurine dioxygenase; Reviewed; Region: tauD; PRK09553
431946001105	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
431946001106	dimer interface [polypeptide binding]; other site
431946001107	active site
431946001108	Schiff base residues; other site
431946001109	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cd00253
431946001110	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
431946001111	Autotransporter beta-domain; Region: Autotransporter; pfam03797
431946001112	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
431946001113	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
431946001114	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
431946001115	microcin B17 transporter; Reviewed; Region: PRK11098
431946001116	Protein of unknown function (DUF1615); Region: DUF1615; pfam07759
431946001117	Protein of unknown function (DUF2755); Region: DUF2755; pfam10954
431946001118	Protein of unknown function (DUF2754); Region: DUF2754; pfam10953
431946001119	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
431946001120	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
431946001121	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
431946001122	anti-RssB factor; Provisional; Region: PRK10244
431946001123	alkaline phosphatase; Provisional; Region: PRK10518
431946001124	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016
431946001125	dimer interface [polypeptide binding]; other site
431946001126	active site
431946001127	hypothetical protein; Provisional; Region: PRK11505
431946001128	psiF repeat; Region: PsiF_repeat; pfam07769
431946001129	psiF repeat; Region: PsiF_repeat; pfam07769
431946001130	diguanylate cyclase AdrA; Provisional; Region: adrA; PRK10245
431946001131	MASE2 domain; Region: MASE2; pfam05230
431946001132	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
431946001133	metal binding site [ion binding]; metal-binding site
431946001134	active site
431946001135	I-site; other site
431946001136	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
431946001137	pyrroline-5-carboxylate reductase; Region: PLN02688
431946001138	hypothetical protein; Validated; Region: PRK00124
431946001139	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
431946001140	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
431946001141	ADP binding site [chemical binding]; other site
431946001142	magnesium binding site [ion binding]; other site
431946001143	putative shikimate binding site; other site
431946001144	hypothetical protein; Provisional; Region: PRK10380
431946001145	hypothetical protein; Provisional; Region: PRK10481
431946001146	hypothetical protein; Provisional; Region: PRK10579
431946001147	Protein of unknown function (DUF2773); Region: DUF2773; pfam10971
431946001148	DNA recombination-dependent growth factor C [DNA replication, recombination, and repair]; Region: RdgC; COG2974
431946001149	fructokinase; Reviewed; Region: PRK09557
431946001150	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
431946001151	nucleotide binding site [chemical binding]; other site
431946001152	MFS transport protein AraJ; Provisional; Region: PRK10091
431946001153	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946001154	putative substrate translocation pore; other site
431946001155	exonuclease subunit SbcC; Provisional; Region: PRK10246
431946001156	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
431946001157	Walker A/P-loop; other site
431946001158	ATP binding site [chemical binding]; other site
431946001159	Q-loop/lid; other site
431946001160	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
431946001161	ABC transporter signature motif; other site
431946001162	Walker B; other site
431946001163	D-loop; other site
431946001164	H-loop/switch region; other site
431946001165	exonuclease subunit SbcD; Provisional; Region: PRK10966
431946001166	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
431946001167	active site
431946001168	metal binding site [ion binding]; metal-binding site
431946001169	DNA binding site [nucleotide binding]
431946001170	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
431946001171	transcriptional regulator PhoB; Provisional; Region: PRK10161
431946001172	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946001173	active site
431946001174	phosphorylation site [posttranslational modification]
431946001175	intermolecular recognition site; other site
431946001176	dimerization interface [polypeptide binding]; other site
431946001177	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
431946001178	DNA binding site [nucleotide binding]
431946001179	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
431946001180	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
431946001181	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
431946001182	putative active site [active]
431946001183	heme pocket [chemical binding]; other site
431946001184	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
431946001185	dimer interface [polypeptide binding]; other site
431946001186	phosphorylation site [posttranslational modification]
431946001187	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946001188	ATP binding site [chemical binding]; other site
431946001189	Mg2+ binding site [ion binding]; other site
431946001190	G-X-G motif; other site
431946001191	branched-chain amino acid transport system 2 carrier protein BrnQ; Provisional; Region: PRK15433
431946001192	putative proline-specific permease; Provisional; Region: proY; PRK10580
431946001193	Spore germination protein; Region: Spore_permease; cl17796
431946001194	maltodextrin glucosidase; Provisional; Region: PRK10785
431946001195	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
431946001196	homodimer interface [polypeptide binding]; other site
431946001197	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
431946001198	active site
431946001199	homodimer interface [polypeptide binding]; other site
431946001200	catalytic site [active]
431946001201	acyl carrier protein phosphodiesterase; Provisional; Region: PRK10045
431946001202	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
431946001203	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
431946001204	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
431946001205	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
431946001206	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
431946001207	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
431946001208	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
431946001209	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
431946001210	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
431946001211	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
431946001212	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
431946001213	Protein export membrane protein; Region: SecD_SecF; pfam02355
431946001214	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
431946001215	active site
431946001216	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
431946001217	hypothetical protein; Provisional; Region: PRK11530
431946001218	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
431946001219	ATP cone domain; Region: ATP-cone; pfam03477
431946001220	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
431946001221	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
431946001222	catalytic motif [active]
431946001223	Zn binding site [ion binding]; other site
431946001224	riboflavin-specific deaminase C-terminal domain; Region: ribD_Cterm; TIGR00227
431946001225	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
431946001226	homopentamer interface [polypeptide binding]; other site
431946001227	active site
431946001228	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
431946001229	putative RNA binding site [nucleotide binding]; other site
431946001230	thiamine monophosphate kinase; Provisional; Region: PRK05731
431946001231	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
431946001232	ATP binding site [chemical binding]; other site
431946001233	dimerization interface [polypeptide binding]; other site
431946001234	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
431946001235	tetramer interfaces [polypeptide binding]; other site
431946001236	binuclear metal-binding site [ion binding]; other site
431946001237	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
431946001238	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
431946001239	active site
431946001240	catalytic tetrad [active]
431946001241	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
431946001242	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
431946001243	TPP-binding site; other site
431946001244	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
431946001245	PYR/PP interface [polypeptide binding]; other site
431946001246	dimer interface [polypeptide binding]; other site
431946001247	TPP binding site [chemical binding]; other site
431946001248	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
431946001249	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
431946001250	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
431946001251	substrate binding pocket [chemical binding]; other site
431946001252	chain length determination region; other site
431946001253	substrate-Mg2+ binding site; other site
431946001254	catalytic residues [active]
431946001255	aspartate-rich region 1; other site
431946001256	active site lid residues [active]
431946001257	aspartate-rich region 2; other site
431946001258	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
431946001259	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
431946001260	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
431946001261	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
431946001262	Ligand Binding Site [chemical binding]; other site
431946001263	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
431946001264	active site residue [active]
431946001265	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
431946001266	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
431946001267	conserved cys residue [active]
431946001268	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
431946001269	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
431946001270	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
431946001271	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
431946001272	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
431946001273	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946001274	Major Facilitator Superfamily; Region: MFS_1; pfam07690
431946001275	putative substrate translocation pore; other site
431946001276	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
431946001277	UbiA prenyltransferase family; Region: UbiA; pfam01040
431946001278	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
431946001279	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
431946001280	Subunit I/III interface [polypeptide binding]; other site
431946001281	Subunit III/IV interface [polypeptide binding]; other site
431946001282	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
431946001283	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
431946001284	D-pathway; other site
431946001285	Putative ubiquinol binding site [chemical binding]; other site
431946001286	Low-spin heme (heme b) binding site [chemical binding]; other site
431946001287	Putative water exit pathway; other site
431946001288	Binuclear center (heme o3/CuB) [ion binding]; other site
431946001289	K-pathway; other site
431946001290	Putative proton exit pathway; other site
431946001291	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
431946001292	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
431946001293	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
431946001294	muropeptide transporter; Reviewed; Region: ampG; PRK11902
431946001295	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946001296	putative substrate translocation pore; other site
431946001297	hypothetical protein; Provisional; Region: PRK11627
431946001298	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
431946001299	transcriptional regulator BolA; Provisional; Region: PRK11628
431946001300	trigger factor; Provisional; Region: tig; PRK01490
431946001301	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
431946001302	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
431946001303	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
431946001304	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
431946001305	oligomer interface [polypeptide binding]; other site
431946001306	active site residues [active]
431946001307	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
431946001308	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
431946001309	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946001310	Walker A motif; other site
431946001311	ATP binding site [chemical binding]; other site
431946001312	Walker B motif; other site
431946001313	Iron permease FTR1 family; Region: FTR1; cl00475
431946001314	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
431946001315	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
431946001316	Found in ATP-dependent protease La (LON); Region: LON; smart00464
431946001317	Found in ATP-dependent protease La (LON); Region: LON; smart00464
431946001318	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946001319	Walker A motif; other site
431946001320	ATP binding site [chemical binding]; other site
431946001321	Walker B motif; other site
431946001322	arginine finger; other site
431946001323	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
431946001324	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
431946001325	IHF dimer interface [polypeptide binding]; other site
431946001326	IHF - DNA interface [nucleotide binding]; other site
431946001327	periplasmic folding chaperone; Provisional; Region: PRK10788
431946001328	SurA N-terminal domain; Region: SurA_N_3; cl07813
431946001329	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
431946001330	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
431946001331	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
431946001332	active site
431946001333	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
431946001334	Ligand Binding Site [chemical binding]; other site
431946001335	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
431946001336	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
431946001337	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
431946001338	thiamin pyrimidine pyrophosphate hydrolase; Provisional; Region: PRK15126
431946001339	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
431946001340	active site
431946001341	motif I; other site
431946001342	motif II; other site
431946001343	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
431946001344	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
431946001345	putative DNA binding site [nucleotide binding]; other site
431946001346	putative Zn2+ binding site [ion binding]; other site
431946001347	AsnC family; Region: AsnC_trans_reg; pfam01037
431946001348	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
431946001349	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
431946001350	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
431946001351	Walker A/P-loop; other site
431946001352	ATP binding site [chemical binding]; other site
431946001353	Q-loop/lid; other site
431946001354	ABC transporter signature motif; other site
431946001355	Walker B; other site
431946001356	D-loop; other site
431946001357	H-loop/switch region; other site
431946001358	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
431946001359	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
431946001360	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
431946001361	Walker A/P-loop; other site
431946001362	ATP binding site [chemical binding]; other site
431946001363	Q-loop/lid; other site
431946001364	ABC transporter signature motif; other site
431946001365	Walker B; other site
431946001366	D-loop; other site
431946001367	H-loop/switch region; other site
431946001368	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
431946001369	Nitrogen regulatory protein P-II; Region: P-II; smart00938
431946001370	ammonium transporter; Provisional; Region: PRK10666
431946001371	acyl-CoA thioesterase II; Provisional; Region: PRK10526
431946001372	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
431946001373	active site
431946001374	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
431946001375	catalytic triad [active]
431946001376	dimer interface [polypeptide binding]; other site
431946001377	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
431946001378	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
431946001379	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
431946001380	DNA binding site [nucleotide binding]
431946001381	active site
431946001382	Protein of unknown function (DUF1428); Region: DUF1428; cl02319
431946001383	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
431946001384	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
431946001385	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
431946001386	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
431946001387	maltose O-acetyltransferase; Provisional; Region: PRK10092
431946001388	Maltose acetyltransferase; Region: Mac; pfam12464
431946001389	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
431946001390	trimer interface [polypeptide binding]; other site
431946001391	active site
431946001392	substrate binding site [chemical binding]; other site
431946001393	CoA binding site [chemical binding]; other site
431946001394	gene expression modulator; Provisional; Region: PRK10945
431946001395	Biofilm formation regulator YbaJ; Region: YbaJ; pfam10757
431946001396	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
431946001397	Protein export membrane protein; Region: SecD_SecF; cl14618
431946001398	Protein export membrane protein; Region: SecD_SecF; cl14618
431946001399	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
431946001400	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
431946001401	HlyD family secretion protein; Region: HlyD_3; pfam13437
431946001402	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
431946001403	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
431946001404	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
431946001405	hypothetical protein; Provisional; Region: PRK11281
431946001406	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
431946001407	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
431946001408	Mechanosensitive ion channel; Region: MS_channel; pfam00924
431946001409	hypothetical protein; Provisional; Region: PRK11038
431946001410	primosomal replication protein N''; Provisional; Region: PRK10093
431946001411	hypothetical protein; Provisional; Region: PRK10527
431946001412	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
431946001413	active site
431946001414	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
431946001415	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946001416	Walker A motif; other site
431946001417	ATP binding site [chemical binding]; other site
431946001418	Walker B motif; other site
431946001419	DNA polymerase III subunit delta'; Validated; Region: PRK08485
431946001420	arginine finger; other site
431946001421	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
431946001422	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
431946001423	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
431946001424	hypothetical protein; Validated; Region: PRK00153
431946001425	Recombinational DNA repair protein (RecF pathway) [DNA replication, recombination, and repair]; Region: RecR; COG0353
431946001426	RecR protein; Region: RecR; pfam02132
431946001427	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
431946001428	putative active site [active]
431946001429	putative metal-binding site [ion binding]; other site
431946001430	tetramer interface [polypeptide binding]; other site
431946001431	heat shock protein 90; Provisional; Region: PRK05218
431946001432	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946001433	ATP binding site [chemical binding]; other site
431946001434	Mg2+ binding site [ion binding]; other site
431946001435	G-X-G motif; other site
431946001436	adenylate kinase; Reviewed; Region: adk; PRK00279
431946001437	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
431946001438	AMP-binding site [chemical binding]; other site
431946001439	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
431946001440	ferrochelatase; Region: hemH; TIGR00109
431946001441	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
431946001442	C-terminal domain interface [polypeptide binding]; other site
431946001443	active site
431946001444	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
431946001445	active site
431946001446	N-terminal domain interface [polypeptide binding]; other site
431946001447	acetyl esterase; Provisional; Region: PRK10162
431946001448	inosine/guanosine kinase; Provisional; Region: PRK15074
431946001449	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
431946001450	putative cation:proton antiport protein; Provisional; Region: PRK10669
431946001451	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
431946001452	TrkA-N domain; Region: TrkA_N; pfam02254
431946001453	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946001454	Major Facilitator Superfamily; Region: MFS_1; pfam07690
431946001455	putative substrate translocation pore; other site
431946001456	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
431946001457	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
431946001458	active site
431946001459	metal binding site [ion binding]; metal-binding site
431946001460	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
431946001461	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
431946001462	putative deacylase active site [active]
431946001463	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3735
431946001464	Plasmid maintenance system killer protein; Region: Plasmid_killer; cl01422
431946001465	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
431946001466	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
431946001467	non-specific DNA binding site [nucleotide binding]; other site
431946001468	salt bridge; other site
431946001469	sequence-specific DNA binding site [nucleotide binding]; other site
431946001470	copper exporting ATPase; Provisional; Region: copA; PRK10671
431946001471	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
431946001472	metal-binding site [ion binding]
431946001473	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
431946001474	metal-binding site [ion binding]
431946001475	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
431946001476	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
431946001477	motif II; other site
431946001478	glutaminase; Reviewed; Region: PRK12356
431946001479	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
431946001480	amino acid transporter; Region: 2A0306; TIGR00909
431946001481	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
431946001482	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
431946001483	DNA binding residues [nucleotide binding]
431946001484	dimer interface [polypeptide binding]; other site
431946001485	copper binding site [ion binding]; other site
431946001486	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
431946001487	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
431946001488	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
431946001489	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
431946001490	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
431946001491	Walker A/P-loop; other site
431946001492	ATP binding site [chemical binding]; other site
431946001493	Q-loop/lid; other site
431946001494	ABC transporter signature motif; other site
431946001495	Walker B; other site
431946001496	D-loop; other site
431946001497	H-loop/switch region; other site
431946001498	Uncharacterized protein family (UPF0014); Region: UPF0014; pfam03649
431946001499	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
431946001500	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
431946001501	oxidoreductase; Provisional; Region: PRK08017
431946001502	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
431946001503	NADP binding site [chemical binding]; other site
431946001504	active site
431946001505	steroid binding site; other site
431946001506	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
431946001507	active site
431946001508	catalytic triad [active]
431946001509	oxyanion hole [active]
431946001510	switch loop; other site
431946001511	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
431946001512	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
431946001513	Walker A/P-loop; other site
431946001514	ATP binding site [chemical binding]; other site
431946001515	Q-loop/lid; other site
431946001516	ABC transporter signature motif; other site
431946001517	Walker B; other site
431946001518	D-loop; other site
431946001519	H-loop/switch region; other site
431946001520	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
431946001521	FtsX-like permease family; Region: FtsX; pfam02687
431946001522	FtsX-like permease family; Region: FtsX; pfam02687
431946001523	Protein of unknown function (DUF796); Region: DUF796; cl01226
431946001524	Uncharacterized conserved protein (DUF2235); Region: DUF2235; cl01480
431946001525	Protein of unknown function (DUF2931); Region: DUF2931; pfam11153
431946001526	Protein of unknown function (DUF2931); Region: DUF2931; pfam11153
431946001527	Protein of unknown function (DUF2931); Region: DUF2931; pfam11153
431946001528	Protein of unknown function (DUF2931); Region: DUF2931; pfam11153
431946001529	tRNA 2-selenouridine synthase; Provisional; Region: PRK11784
431946001530	Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB; Region: RHOD_YbbB; cd01520
431946001531	active site residue [active]
431946001532	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
431946001533	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946001534	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
431946001535	dimerization interface [polypeptide binding]; other site
431946001536	Ureidoglycolate hydrolase [Nucleotide transport and metabolism]; Region: DAL3; COG3194
431946001537	ureidoglycolate hydrolase; Provisional; Region: PRK03606
431946001538	DNA-binding transcriptional repressor AllR; Provisional; Region: PRK10163
431946001539	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
431946001540	Bacterial transcriptional regulator; Region: IclR; pfam01614
431946001541	glyoxylate carboligase; Provisional; Region: PRK11269
431946001542	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
431946001543	PYR/PP interface [polypeptide binding]; other site
431946001544	dimer interface [polypeptide binding]; other site
431946001545	TPP binding site [chemical binding]; other site
431946001546	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
431946001547	Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the...; Region: TPP_Gcl; cd02006
431946001548	TPP-binding site [chemical binding]; other site
431946001549	hydroxypyruvate isomerase; Provisional; Region: PRK09997
431946001550	tartronate semialdehyde reductase; Provisional; Region: PRK15059
431946001551	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
431946001552	nucleobase-cation-symport-1 (NCS1) transporters; solute-binding domain; Region: SLC-NCS1sbd; cd10323
431946001553	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
431946001554	Na binding site [ion binding]; other site
431946001555	substrate binding site [chemical binding]; other site
431946001556	allantoinase; Provisional; Region: PRK08044
431946001557	L-Hydantoinases (L-HYDs) and Allantoinase (ALN); L-Hydantoinases are a member of the dihydropyrimidinase family, which catalyzes the reversible hydrolytic ring opening of dihydropyrimidines and hydantoins (five-membered cyclic diamides used in...; Region: L-HYD_ALN; cd01315
431946001558	active site
431946001559	putative uracil/xanthine transporter; Provisional; Region: PRK11412
431946001560	glycerate kinase II; Provisional; Region: PRK09932
431946001561	Uncharacterized protein, possibly involved in glyoxylate utilization [General function prediction only]; Region: GlxB; COG3257
431946001562	Protein of unknown function (DUF861); Region: Cupin_3; pfam05899
431946001563	Cupin domain; Region: Cupin_2; cl17218
431946001564	allantoate amidohydrolase; Region: AllC; TIGR03176
431946001565	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
431946001566	active site
431946001567	metal binding site [ion binding]; metal-binding site
431946001568	dimer interface [polypeptide binding]; other site
431946001569	ureidoglycolate dehydrogenase; Provisional; Region: PRK15025
431946001570	membrane protein FdrA; Validated; Region: PRK06091
431946001571	CoA binding domain; Region: CoA_binding; pfam02629
431946001572	CoA-ligase; Region: Ligase_CoA; pfam00549
431946001573	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
431946001574	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
431946001575	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
431946001576	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
431946001577	putative substrate binding site [chemical binding]; other site
431946001578	nucleotide binding site [chemical binding]; other site
431946001579	nucleotide binding site [chemical binding]; other site
431946001580	homodimer interface [polypeptide binding]; other site
431946001581	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
431946001582	ATP-grasp domain; Region: ATP-grasp; pfam02222
431946001583	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
431946001584	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
431946001585	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
431946001586	putative active site [active]
431946001587	putative metal binding site [ion binding]; other site
431946001588	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
431946001589	substrate binding site [chemical binding]; other site
431946001590	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
431946001591	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
431946001592	active site
431946001593	HIGH motif; other site
431946001594	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
431946001595	KMSKS motif; other site
431946001596	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
431946001597	tRNA binding surface [nucleotide binding]; other site
431946001598	anticodon binding site; other site
431946001599	Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988
431946001600	ribosome-associated protein; Provisional; Region: PRK11507
431946001601	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
431946001602	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
431946001603	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
431946001604	homodimer interface [polypeptide binding]; other site
431946001605	NADP binding site [chemical binding]; other site
431946001606	substrate binding site [chemical binding]; other site
431946001607	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
431946001608	Methyltransferase domain; Region: Methyltransf_12; pfam08242
431946001609	S-adenosylmethionine binding site [chemical binding]; other site
431946001610	outer membrane protease; Reviewed; Region: PRK10993
431946001611	hypothetical protein; Provisional; Region: PRK09936
431946001612	bacteriophage N4 receptor, outer membrane subunit; Provisional; Region: PRK09782
431946001613	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
431946001614	TPR motif; other site
431946001615	binding surface
431946001616	Bacteriophage N adsorption protein A C-term; Region: NfrA_C; pfam13283
431946001617	bacteriophage N4 adsorption protein B; Provisional; Region: nfrB; PRK11234
431946001618	active site
431946001619	Glycosyl transferase family group 2; Region: Glyco_trans_2_3; pfam13632
431946001620	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
431946001621	sensor kinase CusS; Provisional; Region: PRK09835
431946001622	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
431946001623	dimerization interface [polypeptide binding]; other site
431946001624	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
431946001625	dimer interface [polypeptide binding]; other site
431946001626	phosphorylation site [posttranslational modification]
431946001627	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946001628	ATP binding site [chemical binding]; other site
431946001629	Mg2+ binding site [ion binding]; other site
431946001630	G-X-G motif; other site
431946001631	DNA-binding transcriptional activator CusR; Provisional; Region: PRK09836
431946001632	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946001633	active site
431946001634	phosphorylation site [posttranslational modification]
431946001635	intermolecular recognition site; other site
431946001636	dimerization interface [polypeptide binding]; other site
431946001637	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
431946001638	DNA binding site [nucleotide binding]
431946001639	copper/silver efflux system outer membrane protein CusC; Provisional; Region: PRK09837
431946001640	periplasmic copper-binding protein; Provisional; Region: PRK09838
431946001641	copper/silver efflux system membrane fusion protein CusB; Provisional; Region: PRK09783
431946001642	HlyD family secretion protein; Region: HlyD_3; pfam13437
431946001643	heavy metal efflux pump, CzcA family; Region: 2A0601; TIGR00914
431946001644	phenylalanine transporter; Provisional; Region: PRK10249
431946001645	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
431946001646	Mechanosensitive ion channel; Region: MS_channel; pfam00924
431946001647	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
431946001648	dimer interface [polypeptide binding]; other site
431946001649	FMN binding site [chemical binding]; other site
431946001650	hypothetical protein; Provisional; Region: PRK10250
431946001651	Protein of unknown function (DUF1158); Region: DUF1158; pfam06643
431946001652	gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516
431946001653	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
431946001654	Hok/gef family; Region: HOK_GEF; pfam01848
431946001655	short chain dehydrogenase; Provisional; Region: PRK06114
431946001656	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
431946001657	NAD(P) binding site [chemical binding]; other site
431946001658	active site
431946001659	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
431946001660	meso-2,3-butanediol dehydrogenase-like, classical (c) SDRs; Region: meso-BDH-like_SDR_c; cd05366
431946001661	NAD binding site [chemical binding]; other site
431946001662	homotetramer interface [polypeptide binding]; other site
431946001663	homodimer interface [polypeptide binding]; other site
431946001664	active site
431946001665	substrate binding site [chemical binding]; other site
431946001666	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
431946001667	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
431946001668	TM-ABC transporter signature motif; other site
431946001669	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
431946001670	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
431946001671	Walker A/P-loop; other site
431946001672	ATP binding site [chemical binding]; other site
431946001673	Q-loop/lid; other site
431946001674	ABC transporter signature motif; other site
431946001675	Walker B; other site
431946001676	D-loop; other site
431946001677	H-loop/switch region; other site
431946001678	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
431946001679	Predicted periplasmic lipoprotein (DUF2291); Region: DUF2291; cl02395
431946001680	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
431946001681	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
431946001682	bacterial glycerol kinase 2-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_GK2_bacteria; cd07791
431946001683	Glycerol kinase [Energy production and conversion]; Region: GlpK; COG0554
431946001684	N- and C-terminal domain interface [polypeptide binding]; other site
431946001685	active site
431946001686	MgATP binding site [chemical binding]; other site
431946001687	catalytic site [active]
431946001688	metal binding site [ion binding]; metal-binding site
431946001689	putative homotetramer interface [polypeptide binding]; other site
431946001690	putative homodimer interface [polypeptide binding]; other site
431946001691	glycerol binding site [chemical binding]; other site
431946001692	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
431946001693	MarR family; Region: MarR_2; cl17246
431946001694	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
431946001695	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
431946001696	TPP-binding site [chemical binding]; other site
431946001697	dimer interface [polypeptide binding]; other site
431946001698	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
431946001699	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
431946001700	PYR/PP interface [polypeptide binding]; other site
431946001701	dimer interface [polypeptide binding]; other site
431946001702	TPP binding site [chemical binding]; other site
431946001703	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
431946001704	phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex; Provisional; Region: PRK10251
431946001705	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
431946001706	outer membrane receptor FepA; Provisional; Region: PRK13524
431946001707	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
431946001708	N-terminal plug; other site
431946001709	ligand-binding site [chemical binding]; other site
431946001710	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
431946001711	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
431946001712	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
431946001713	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3251
431946001714	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
431946001715	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
431946001716	acyl-activating enzyme (AAE) consensus motif; other site
431946001717	AMP binding site [chemical binding]; other site
431946001718	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
431946001719	LPS O-antigen length regulator; Provisional; Region: PRK10381
431946001720	Chain length determinant protein; Region: Wzz; pfam02706
431946001721	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
431946001722	iron-enterobactin transporter ATP-binding protein; Provisional; Region: PRK10253
431946001723	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
431946001724	Walker A/P-loop; other site
431946001725	ATP binding site [chemical binding]; other site
431946001726	Q-loop/lid; other site
431946001727	ABC transporter signature motif; other site
431946001728	Walker B; other site
431946001729	D-loop; other site
431946001730	H-loop/switch region; other site
431946001731	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
431946001732	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
431946001733	ABC-ATPase subunit  interface; other site
431946001734	dimer interface [polypeptide binding]; other site
431946001735	putative PBP binding regions; other site
431946001736	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
431946001737	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
431946001738	ABC-ATPase subunit  interface; other site
431946001739	dimer interface [polypeptide binding]; other site
431946001740	putative PBP binding regions; other site
431946001741	enterobactin exporter EntS; Provisional; Region: PRK10489
431946001742	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946001743	putative substrate translocation pore; other site
431946001744	iron-enterobactin transporter periplasmic binding protein; Provisional; Region: PRK10957
431946001745	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
431946001746	siderophore binding site; other site
431946001747	isochorismate synthase EntC; Provisional; Region: PRK15016
431946001748	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
431946001749	enterobactin synthase subunit E; Provisional; Region: entE; PRK10946
431946001750	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
431946001751	acyl-activating enzyme (AAE) consensus motif; other site
431946001752	active site
431946001753	AMP binding site [chemical binding]; other site
431946001754	substrate binding site [chemical binding]; other site
431946001755	Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013
431946001756	hydrophobic substrate binding pocket; other site
431946001757	Isochorismatase family; Region: Isochorismatase; pfam00857
431946001758	active site
431946001759	conserved cis-peptide bond; other site
431946001760	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
431946001761	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
431946001762	2,3 dihydro-2,3 dihydrozybenzoate dehydrogenases, classical (c) SDRs; Region: DH-DHB-DH_SDR_c; cd05331
431946001763	putative NAD(P) binding site [chemical binding]; other site
431946001764	active site
431946001765	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
431946001766	CoenzymeA binding site [chemical binding]; other site
431946001767	subunit interaction site [polypeptide binding]; other site
431946001768	PHB binding site; other site
431946001769	carbon starvation protein A; Provisional; Region: PRK15015
431946001770	Carbon starvation protein CstA; Region: CstA; pfam02554
431946001771	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
431946001772	Uncharacterized small protein [Function unknown]; Region: COG2879
431946001773	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
431946001774	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
431946001775	putative active site [active]
431946001776	metal binding site [ion binding]; metal-binding site
431946001777	methionine aminotransferase; Validated; Region: PRK09082
431946001778	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
431946001779	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946001780	homodimer interface [polypeptide binding]; other site
431946001781	catalytic residue [active]
431946001782	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
431946001783	ParB-like nuclease domain; Region: ParBc; pfam02195
431946001784	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
431946001785	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
431946001786	Active Sites [active]
431946001787	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
431946001788	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
431946001789	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946001790	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
431946001791	dimerization interface [polypeptide binding]; other site
431946001792	disulfide isomerase/thiol-disulfide oxidase; Provisional; Region: dsbG; PRK11657
431946001793	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
431946001794	dimerization domain [polypeptide binding]; other site
431946001795	dimer interface [polypeptide binding]; other site
431946001796	catalytic residues [active]
431946001797	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
431946001798	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
431946001799	dimer interface [polypeptide binding]; other site
431946001800	decamer (pentamer of dimers) interface [polypeptide binding]; other site
431946001801	catalytic triad [active]
431946001802	peroxidatic and resolving cysteines [active]
431946001803	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
431946001804	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
431946001805	catalytic residue [active]
431946001806	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
431946001807	catalytic residues [active]
431946001808	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
431946001809	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
431946001810	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
431946001811	Ligand Binding Site [chemical binding]; other site
431946001812	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
431946001813	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
431946001814	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062
431946001815	B1 nucleotide binding pocket [chemical binding]; other site
431946001816	B2 nucleotide binding pocket [chemical binding]; other site
431946001817	CAS motifs; other site
431946001818	active site
431946001819	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
431946001820	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
431946001821	transmembrane helices; other site
431946001822	triphosphoribosyl-dephospho-CoA synthase; Provisional; Region: citG; PRK10096
431946001823	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
431946001824	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
431946001825	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
431946001826	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
431946001827	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
431946001828	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
431946001829	putative active site [active]
431946001830	(T/H)XGH motif; other site
431946001831	sensor histidine kinase DpiB; Provisional; Region: dpiB; PRK15053
431946001832	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
431946001833	putative active site [active]
431946001834	heme pocket [chemical binding]; other site
431946001835	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946001836	ATP binding site [chemical binding]; other site
431946001837	Mg2+ binding site [ion binding]; other site
431946001838	G-X-G motif; other site
431946001839	two-component response regulator DpiA; Provisional; Region: dpiA; PRK10046
431946001840	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946001841	active site
431946001842	phosphorylation site [posttranslational modification]
431946001843	intermolecular recognition site; other site
431946001844	dimerization interface [polypeptide binding]; other site
431946001845	Transcriptional regulator; Region: CitT; pfam12431
431946001846	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
431946001847	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
431946001848	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
431946001849	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
431946001850	DNA-binding site [nucleotide binding]; DNA binding site
431946001851	RNA-binding motif; other site
431946001852	chromosome condensation membrane protein; Provisional; Region: PRK14196
431946001853	Predicted amidohydrolase [General function prediction only]; Region: COG0388
431946001854	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_3; cd07581
431946001855	putative active site [active]
431946001856	catalytic triad [active]
431946001857	putative dimer interface [polypeptide binding]; other site
431946001858	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
431946001859	lipoyl synthase; Provisional; Region: PRK05481
431946001860	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
431946001861	FeS/SAM binding site; other site
431946001862	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
431946001863	lipoate-protein ligase B; Provisional; Region: PRK14342
431946001864	hypothetical protein; Provisional; Region: PRK04998
431946001865	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
431946001866	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
431946001867	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
431946001868	rare lipoprotein A; Provisional; Region: PRK10672
431946001869	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
431946001870	Sporulation related domain; Region: SPOR; pfam05036
431946001871	cell wall shape-determining protein; Provisional; Region: PRK10794
431946001872	penicillin-binding protein 2; Provisional; Region: PRK10795
431946001873	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
431946001874	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
431946001875	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
431946001876	ribosome-associated protein; Provisional; Region: PRK11538
431946001877	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
431946001878	catalytic core [active]
431946001879	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
431946001880	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
431946001881	active site
431946001882	(T/H)XGH motif; other site
431946001883	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
431946001884	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
431946001885	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
431946001886	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
431946001887	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
431946001888	HIGH motif; other site
431946001889	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
431946001890	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
431946001891	active site
431946001892	KMSKS motif; other site
431946001893	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
431946001894	tRNA binding surface [nucleotide binding]; other site
431946001895	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
431946001896	hypothetical protein; Provisional; Region: PRK11032
431946001897	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
431946001898	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
431946001899	Sel1 repeat; Region: Sel1; cl02723
431946001900	Sel1 repeat; Region: Sel1; cl02723
431946001901	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
431946001902	Sel1-like repeats; Region: SEL1; smart00671
431946001903	Sel1-like repeats; Region: SEL1; smart00671
431946001904	Sel1-like repeats; Region: SEL1; smart00671
431946001905	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
431946001906	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cl02542
431946001907	Molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: DnaK; COG0443
431946001908	Nucleotide-binding domain of Escherichia coli HscC and similar proteins; Region: HscC_like_NBD; cd10235
431946001909	nucleotide binding site [chemical binding]; other site
431946001910	putative NEF/HSP70 interaction site [polypeptide binding]; other site
431946001911	SBD interface [polypeptide binding]; other site
431946001912	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
431946001913	active site
431946001914	tetramer interface [polypeptide binding]; other site
431946001915	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
431946001916	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
431946001917	Walker A/P-loop; other site
431946001918	ATP binding site [chemical binding]; other site
431946001919	Q-loop/lid; other site
431946001920	ABC transporter signature motif; other site
431946001921	Walker B; other site
431946001922	D-loop; other site
431946001923	H-loop/switch region; other site
431946001924	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
431946001925	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946001926	dimer interface [polypeptide binding]; other site
431946001927	conserved gate region; other site
431946001928	putative PBP binding loops; other site
431946001929	ABC-ATPase subunit interface; other site
431946001930	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
431946001931	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946001932	dimer interface [polypeptide binding]; other site
431946001933	conserved gate region; other site
431946001934	putative PBP binding loops; other site
431946001935	ABC-ATPase subunit interface; other site
431946001936	glutamate and aspartate transporter subunit; Provisional; Region: PRK10797
431946001937	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
431946001938	substrate binding pocket [chemical binding]; other site
431946001939	membrane-bound complex binding site; other site
431946001940	hinge residues; other site
431946001941	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
431946001942	Uncharacterized conserved protein [Function unknown]; Region: COG3391
431946001943	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
431946001944	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
431946001945	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
431946001946	putative active site [active]
431946001947	catalytic triad [active]
431946001948	putative dimer interface [polypeptide binding]; other site
431946001949	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
431946001950	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
431946001951	Transporter associated domain; Region: CorC_HlyC; smart01091
431946001952	metal-binding heat shock protein; Provisional; Region: PRK00016
431946001953	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
431946001954	PhoH-like protein; Region: PhoH; pfam02562
431946001955	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
431946001956	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
431946001957	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
431946001958	FeS/SAM binding site; other site
431946001959	TRAM domain; Region: TRAM; pfam01938
431946001960	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
431946001961	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
431946001962	asparagine synthetase B; Provisional; Region: asnB; PRK09431
431946001963	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
431946001964	active site
431946001965	dimer interface [polypeptide binding]; other site
431946001966	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
431946001967	Ligand Binding Site [chemical binding]; other site
431946001968	Molecular Tunnel; other site
431946001969	UMP phosphatase; Provisional; Region: PRK10444
431946001970	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
431946001971	active site
431946001972	motif I; other site
431946001973	motif II; other site
431946001974	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
431946001975	MarR family; Region: MarR; pfam01047
431946001976	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
431946001977	ROK family; Region: ROK; pfam00480
431946001978	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
431946001979	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
431946001980	active site
431946001981	dimer interface [polypeptide binding]; other site
431946001982	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
431946001983	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
431946001984	active site
431946001985	trimer interface [polypeptide binding]; other site
431946001986	allosteric site; other site
431946001987	active site lid [active]
431946001988	hexamer (dimer of trimers) interface [polypeptide binding]; other site
431946001989	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
431946001990	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
431946001991	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
431946001992	active site turn [active]
431946001993	phosphorylation site [posttranslational modification]
431946001994	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
431946001995	HPr interaction site; other site
431946001996	glycerol kinase (GK) interaction site [polypeptide binding]; other site
431946001997	active site
431946001998	phosphorylation site [posttranslational modification]
431946001999	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
431946002000	transmembrane helices; other site
431946002001	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
431946002002	Domain of unknown function (DUF386); Region: DUF386; cl01047
431946002003	Predicted neuraminidase (sialidase) [Carbohydrate transport and metabolism]; Region: COG4692
431946002004	BNR repeat-like domain; Region: BNR_2; pfam13088
431946002005	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
431946002006	dihydrodipicolinate synthase; Region: dapA; TIGR00674
431946002007	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
431946002008	inhibitor site; inhibition site
431946002009	active site
431946002010	dimer interface [polypeptide binding]; other site
431946002011	catalytic residue [active]
431946002012	5-hydroxyvalerate dehydrogenase (HVD) catalyzes the oxidation of 5-hydroxyvalerate to 5-oxovalerate with NAD+ as cofactor; Region: HVD; cd08193
431946002013	Iron-containing alcohol dehydrogenase; Region: Fe-ADH; pfam00465
431946002014	putative active site [active]
431946002015	metal binding site [ion binding]; metal-binding site
431946002016	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
431946002017	Pyridoxal phosphate biosynthetic protein PdxA; Region: PdxA; cl00873
431946002018	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
431946002019	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
431946002020	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
431946002021	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
431946002022	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
431946002023	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
431946002024	active site
431946002025	HIGH motif; other site
431946002026	nucleotide binding site [chemical binding]; other site
431946002027	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
431946002028	KMSKS motif; other site
431946002029	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
431946002030	outer membrane porin, OprD family; Region: OprD; pfam03573
431946002031	YbfN-like lipoprotein; Region: YbfN; pfam13982
431946002032	ferric uptake regulator; Provisional; Region: fur; PRK09462
431946002033	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
431946002034	metal binding site 2 [ion binding]; metal-binding site
431946002035	putative DNA binding helix; other site
431946002036	metal binding site 1 [ion binding]; metal-binding site
431946002037	dimer interface [polypeptide binding]; other site
431946002038	structural Zn2+ binding site [ion binding]; other site
431946002039	flavodoxin FldA; Validated; Region: PRK09267
431946002040	LexA regulated protein; Provisional; Region: PRK11675
431946002041	acyl-CoA esterase; Provisional; Region: PRK10673
431946002042	PGAP1-like protein; Region: PGAP1; pfam07819
431946002043	replication initiation regulator SeqA; Provisional; Region: PRK11187
431946002044	phosphoglucomutase, alpha-D-glucose phosphate-specific; Region: pgm; TIGR01132
431946002045	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
431946002046	active site
431946002047	substrate binding site [chemical binding]; other site
431946002048	metal binding site [ion binding]; metal-binding site
431946002049	putrescine transporter; Provisional; Region: potE; PRK10655
431946002050	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
431946002051	ornithine decarboxylase; Provisional; Region: PRK13578
431946002052	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
431946002053	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
431946002054	homodimer interface [polypeptide binding]; other site
431946002055	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946002056	catalytic residue [active]
431946002057	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
431946002058	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
431946002059	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946002060	active site
431946002061	phosphorylation site [posttranslational modification]
431946002062	intermolecular recognition site; other site
431946002063	dimerization interface [polypeptide binding]; other site
431946002064	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
431946002065	DNA binding site [nucleotide binding]
431946002066	sensor protein KdpD; Provisional; Region: PRK10490
431946002067	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
431946002068	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
431946002069	Ligand Binding Site [chemical binding]; other site
431946002070	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
431946002071	GAF domain; Region: GAF_3; pfam13492
431946002072	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
431946002073	dimer interface [polypeptide binding]; other site
431946002074	phosphorylation site [posttranslational modification]
431946002075	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946002076	ATP binding site [chemical binding]; other site
431946002077	Mg2+ binding site [ion binding]; other site
431946002078	G-X-G motif; other site
431946002079	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
431946002080	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
431946002081	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
431946002082	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
431946002083	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
431946002084	hypothetical protein; Provisional; Region: PRK10167
431946002085	Uncharacterized conserved protein [Function unknown]; Region: COG3272
431946002086	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
431946002087	DNA photolyase; Region: DNA_photolyase; pfam00875
431946002088	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
431946002089	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946002090	putative substrate translocation pore; other site
431946002091	POT family; Region: PTR2; pfam00854
431946002092	Uncharacterized conserved protein [Function unknown]; Region: COG0327
431946002093	metal-binding protein; Provisional; Region: PRK10799
431946002094	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
431946002095	sensor histidine kinase inhibitor, KipI family; Region: TIGR00370
431946002096	biotin-dependent carboxylase uncharacterized domain; Region: urea_amlyse_rel; TIGR00724
431946002097	Escherichia coli putative lactam utilization protein YbgL and similar proteins; Region: LamB_YcsF_YbgL_like; cd10800
431946002098	putative active site [active]
431946002099	endonuclease VIII; Provisional; Region: PRK10445
431946002100	N-terminal domain of Escherichia coli Nei/endonuclease VIII and related DNA glycosylases; Region: EcNei-like_N; cd08965
431946002101	DNA binding site [nucleotide binding]
431946002102	catalytic residue [active]
431946002103	putative catalytic residues [active]
431946002104	H2TH interface [polypeptide binding]; other site
431946002105	intercalation triad [nucleotide binding]; other site
431946002106	substrate specificity determining residue; other site
431946002107	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
431946002108	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
431946002109	Putative ammonia monooxygenase; Region: AmoA; pfam05145
431946002110	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
431946002111	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
431946002112	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
431946002113	DNA-binding site [nucleotide binding]; DNA binding site
431946002114	Transcriptional regulators [Transcription]; Region: FadR; COG2186
431946002115	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
431946002116	Demethylmenaquinone methyltransferase; Region: Methyltransf_6; cl00480
431946002117	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
431946002118	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
431946002119	putative NAD(P) binding site [chemical binding]; other site
431946002120	catalytic Zn binding site [ion binding]; other site
431946002121	structural Zn binding site [ion binding]; other site
431946002122	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
431946002123	classical (c) SDRs; Region: SDR_c; cd05233
431946002124	NAD(P) binding site [chemical binding]; other site
431946002125	active site
431946002126	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
431946002127	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
431946002128	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
431946002129	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; cl15441
431946002130	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
431946002131	DctM-like transporters; Region: DctM; pfam06808
431946002132	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593
431946002133	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
431946002134	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
431946002135	dimer interface [polypeptide binding]; other site
431946002136	active site
431946002137	citrylCoA binding site [chemical binding]; other site
431946002138	NADH binding [chemical binding]; other site
431946002139	cationic pore residues; other site
431946002140	oxalacetate/citrate binding site [chemical binding]; other site
431946002141	coenzyme A binding site [chemical binding]; other site
431946002142	catalytic triad [active]
431946002143	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
431946002144	Iron-sulfur protein interface; other site
431946002145	proximal quinone binding site [chemical binding]; other site
431946002146	SdhD (CybS) interface [polypeptide binding]; other site
431946002147	proximal heme binding site [chemical binding]; other site
431946002148	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
431946002149	SdhC subunit interface [polypeptide binding]; other site
431946002150	proximal heme binding site [chemical binding]; other site
431946002151	cardiolipin binding site; other site
431946002152	Iron-sulfur protein interface; other site
431946002153	proximal quinone binding site [chemical binding]; other site
431946002154	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
431946002155	L-aspartate oxidase; Provisional; Region: PRK06175
431946002156	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
431946002157	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
431946002158	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
431946002159	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
431946002160	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
431946002161	TPP-binding site [chemical binding]; other site
431946002162	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
431946002163	dimer interface [polypeptide binding]; other site
431946002164	PYR/PP interface [polypeptide binding]; other site
431946002165	TPP binding site [chemical binding]; other site
431946002166	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
431946002167	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
431946002168	E3 interaction surface; other site
431946002169	lipoyl attachment site [posttranslational modification]; other site
431946002170	e3 binding domain; Region: E3_binding; pfam02817
431946002171	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
431946002172	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
431946002173	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
431946002174	CoA-ligase; Region: Ligase_CoA; pfam00549
431946002175	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
431946002176	CoA binding domain; Region: CoA_binding; smart00881
431946002177	CoA-ligase; Region: Ligase_CoA; pfam00549
431946002178	DNA-binding transcriptional repressor MngR; Provisional; Region: PRK09764
431946002179	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
431946002180	DNA-binding site [nucleotide binding]; DNA binding site
431946002181	UTRA domain; Region: UTRA; pfam07702
431946002182	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
431946002183	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
431946002184	active site
431946002185	phosphorylation site [posttranslational modification]
431946002186	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
431946002187	active site
431946002188	P-loop; other site
431946002189	phosphorylation site [posttranslational modification]
431946002190	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
431946002191	alpha-mannosidase; Provisional; Region: PRK09819
431946002192	N-terminal catalytic domain of Escherichia coli alpha-mannosidase MngB and its bacterial homologs; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_EcMngB_like; cd10815
431946002193	active site
431946002194	metal binding site [ion binding]; metal-binding site
431946002195	catalytic site [active]
431946002196	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; smart00872
431946002197	TPR repeat; Region: TPR_11; pfam13414
431946002198	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
431946002199	binding surface
431946002200	TPR motif; other site
431946002201	Tetratricopeptide repeat; Region: TPR_12; pfam13424
431946002202	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
431946002203	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
431946002204	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003
431946002205	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
431946002206	hypothetical protein; Provisional; Region: PRK10588
431946002207	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
431946002208	active site
431946002209	colicin uptake protein TolQ; Provisional; Region: PRK10801
431946002210	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
431946002211	colicin uptake protein TolR; Provisional; Region: PRK11024
431946002212	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
431946002213	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
431946002214	TolA C-terminal; Region: TolA; pfam06519
431946002215	translocation protein TolB; Provisional; Region: tolB; PRK03629
431946002216	TolB amino-terminal domain; Region: TolB_N; pfam04052
431946002217	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
431946002218	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
431946002219	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
431946002220	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
431946002221	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
431946002222	ligand binding site [chemical binding]; other site
431946002223	tol-pal system protein YbgF; Provisional; Region: PRK10803
431946002224	Tetratricopeptide repeat; Region: TPR_6; pfam13174
431946002225	Tetratricopeptide repeat; Region: TPR_6; pfam13174
431946002226	quinolinate synthetase; Provisional; Region: PRK09375
431946002227	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
431946002228	zinc transporter ZitB; Provisional; Region: PRK03557
431946002229	YbgS-like protein; Region: YbgS; pfam13985
431946002230	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
431946002231	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
431946002232	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
431946002233	catalytic core [active]
431946002234	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
431946002235	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
431946002236	active site
431946002237	catalytic residues [active]
431946002238	galactokinase; Provisional; Region: PRK05101
431946002239	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
431946002240	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
431946002241	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
431946002242	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
431946002243	dimer interface [polypeptide binding]; other site
431946002244	active site
431946002245	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
431946002246	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
431946002247	NAD binding site [chemical binding]; other site
431946002248	homodimer interface [polypeptide binding]; other site
431946002249	active site
431946002250	substrate binding site [chemical binding]; other site
431946002251	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
431946002252	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
431946002253	Walker A/P-loop; other site
431946002254	ATP binding site [chemical binding]; other site
431946002255	Q-loop/lid; other site
431946002256	ABC transporter signature motif; other site
431946002257	Walker B; other site
431946002258	D-loop; other site
431946002259	H-loop/switch region; other site
431946002260	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
431946002261	Walker A/P-loop; other site
431946002262	ATP binding site [chemical binding]; other site
431946002263	Q-loop/lid; other site
431946002264	ABC transporter signature motif; other site
431946002265	Walker B; other site
431946002266	D-loop; other site
431946002267	H-loop/switch region; other site
431946002268	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
431946002269	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
431946002270	molybdenum-pterin binding domain; Region: Mop; TIGR00638
431946002271	TOBE domain; Region: TOBE; pfam03459
431946002272	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
431946002273	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
431946002274	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
431946002275	substrate binding pocket [chemical binding]; other site
431946002276	membrane-bound complex binding site; other site
431946002277	hinge residues; other site
431946002278	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
431946002279	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946002280	dimer interface [polypeptide binding]; other site
431946002281	conserved gate region; other site
431946002282	putative PBP binding loops; other site
431946002283	ABC-ATPase subunit interface; other site
431946002284	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
431946002285	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
431946002286	Walker A/P-loop; other site
431946002287	ATP binding site [chemical binding]; other site
431946002288	Q-loop/lid; other site
431946002289	ABC transporter signature motif; other site
431946002290	Walker B; other site
431946002291	D-loop; other site
431946002292	H-loop/switch region; other site
431946002293	molybdenum-pterin binding domain; Region: Mop; TIGR00638
431946002294	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
431946002295	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
431946002296	motif II; other site
431946002297	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
431946002298	6-phosphogluconolactonase; Provisional; Region: PRK11028
431946002299	Transcriptional regulator [Transcription]; Region: LysR; COG0583
431946002300	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946002301	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
431946002302	putative dimerization interface [polypeptide binding]; other site
431946002303	PrpF protein; Region: PrpF; pfam04303
431946002304	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
431946002305	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
431946002306	transmembrane helices; other site
431946002307	putative hydratase; Provisional; Region: PRK11413
431946002308	Aconitase catalytic domain; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: Aconitase; cl00285
431946002309	substrate binding site [chemical binding]; other site
431946002310	ligand binding site [chemical binding]; other site
431946002311	Aconitase swivel domain. Aconitase (aconitate hydratase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes swivelling conformational change in the enzyme...; Region: Aconitase_swivel; cl00215
431946002312	substrate binding site [chemical binding]; other site
431946002313	acyl-CoA thioesterase; Provisional; Region: PRK10531
431946002314	putative pectinesterase; Region: PLN02432; cl01911
431946002315	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
431946002316	substrate binding site [chemical binding]; other site
431946002317	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
431946002318	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
431946002319	inhibitor-cofactor binding pocket; inhibition site
431946002320	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946002321	catalytic residue [active]
431946002322	biotin synthase; Provisional; Region: PRK15108
431946002323	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
431946002324	FeS/SAM binding site; other site
431946002325	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
431946002326	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
431946002327	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
431946002328	substrate-cofactor binding pocket; other site
431946002329	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946002330	catalytic residue [active]
431946002331	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
431946002332	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946002333	S-adenosylmethionine binding site [chemical binding]; other site
431946002334	AAA domain; Region: AAA_26; pfam13500
431946002335	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
431946002336	Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the biotin biosynthesis pathway in Escherichia coli and other microorganisms. The enzyme catalyzes formation of the ureido ring of dethiobiotin from (7R,8S)-7,8-diaminononanoic acid (DAPA) and...; Region: DTBS; cd03109
431946002337	ADP binding site [chemical binding]; other site
431946002338	excinuclease ABC subunit B; Provisional; Region: PRK05298
431946002339	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
431946002340	ATP binding site [chemical binding]; other site
431946002341	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
431946002342	nucleotide binding region [chemical binding]; other site
431946002343	ATP-binding site [chemical binding]; other site
431946002344	Ultra-violet resistance protein B; Region: UvrB; pfam12344
431946002345	UvrB/uvrC motif; Region: UVR; pfam02151
431946002346	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
431946002347	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
431946002348	putative substrate binding pocket [chemical binding]; other site
431946002349	dimer interface [polypeptide binding]; other site
431946002350	phosphate binding site [ion binding]; other site
431946002351	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
431946002352	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
431946002353	FeS/SAM binding site; other site
431946002354	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
431946002355	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
431946002356	MPT binding site; other site
431946002357	trimer interface [polypeptide binding]; other site
431946002358	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
431946002359	trimer interface [polypeptide binding]; other site
431946002360	dimer interface [polypeptide binding]; other site
431946002361	putative active site [active]
431946002362	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
431946002363	MoaE interaction surface [polypeptide binding]; other site
431946002364	MoeB interaction surface [polypeptide binding]; other site
431946002365	thiocarboxylated glycine; other site
431946002366	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
431946002367	MoaE homodimer interface [polypeptide binding]; other site
431946002368	MoaD interaction [polypeptide binding]; other site
431946002369	active site residues [active]
431946002370	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
431946002371	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
431946002372	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
431946002373	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
431946002374	Predicted integral membrane protein [Function unknown]; Region: COG0392
431946002375	cardiolipin synthase 2; Provisional; Region: PRK11263
431946002376	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
431946002377	putative active site [active]
431946002378	catalytic site [active]
431946002379	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
431946002380	putative active site [active]
431946002381	catalytic site [active]
431946002382	Metal-dependent hydrolase [General function prediction only]; Region: ElsH; COG3568
431946002383	putative catalytic site [active]
431946002384	putative metal binding site [ion binding]; other site
431946002385	putative phosphate binding site [ion binding]; other site
431946002386	Putative inner membrane protein YbhQ; Region: YbhQ; pfam11076
431946002387	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
431946002388	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
431946002389	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
431946002390	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
431946002391	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
431946002392	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
431946002393	Walker A/P-loop; other site
431946002394	ATP binding site [chemical binding]; other site
431946002395	Q-loop/lid; other site
431946002396	ABC transporter signature motif; other site
431946002397	Walker B; other site
431946002398	D-loop; other site
431946002399	H-loop/switch region; other site
431946002400	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
431946002401	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
431946002402	Walker A/P-loop; other site
431946002403	ATP binding site [chemical binding]; other site
431946002404	Q-loop/lid; other site
431946002405	ABC transporter signature motif; other site
431946002406	Walker B; other site
431946002407	D-loop; other site
431946002408	H-loop/switch region; other site
431946002409	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
431946002410	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
431946002411	HlyD family secretion protein; Region: HlyD_3; pfam13437
431946002412	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
431946002413	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
431946002414	ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590
431946002415	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
431946002416	ATP binding site [chemical binding]; other site
431946002417	Mg++ binding site [ion binding]; other site
431946002418	motif III; other site
431946002419	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
431946002420	nucleotide binding region [chemical binding]; other site
431946002421	ATP-binding site [chemical binding]; other site
431946002422	Domain of unknown function (DUF1768); Region: DUF1768; cl01271
431946002423	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
431946002424	DEAD_2; Region: DEAD_2; pfam06733
431946002425	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
431946002426	glycosyl transferase family protein; Provisional; Region: PRK08136
431946002427	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
431946002428	putative dehydrogenase; Provisional; Region: PRK10098
431946002429	hypothetical protein; Provisional; Region: PRK10259
431946002430	hypothetical protein; Provisional; Region: PRK11019
431946002431	Fe(II)-dependent oxygenase superfamily protein; Provisional; Region: PRK05467
431946002432	catecholate siderophore receptor Fiu; Provisional; Region: PRK09840
431946002433	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
431946002434	N-terminal plug; other site
431946002435	ligand-binding site [chemical binding]; other site
431946002436	hypothetical protein; Provisional; Region: PRK10259
431946002437	23S rRNA mA1618 methyltransferase; Provisional; Region: PRK11727
431946002438	Protein of unknown function (DUF890); Region: Methyltransf_10; pfam05971
431946002439	putative mechanosensitive channel protein; Provisional; Region: PRK11465
431946002440	Mechanosensitive ion channel; Region: MS_channel; pfam00924
431946002441	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
431946002442	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
431946002443	Walker A/P-loop; other site
431946002444	ATP binding site [chemical binding]; other site
431946002445	Q-loop/lid; other site
431946002446	ABC transporter signature motif; other site
431946002447	Walker B; other site
431946002448	D-loop; other site
431946002449	H-loop/switch region; other site
431946002450	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
431946002451	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946002452	dimer interface [polypeptide binding]; other site
431946002453	conserved gate region; other site
431946002454	putative PBP binding loops; other site
431946002455	ABC-ATPase subunit interface; other site
431946002456	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
431946002457	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
431946002458	substrate binding pocket [chemical binding]; other site
431946002459	membrane-bound complex binding site; other site
431946002460	hinge residues; other site
431946002461	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
431946002462	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
431946002463	dimerization interface [polypeptide binding]; other site
431946002464	DPS ferroxidase diiron center [ion binding]; other site
431946002465	ion pore; other site
431946002466	threonine and homoserine efflux system; Provisional; Region: PRK10532
431946002467	EamA-like transporter family; Region: EamA; pfam00892
431946002468	outer membrane protein X; Provisional; Region: ompX; PRK09408
431946002469	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
431946002470	Sulfatase; Region: Sulfatase; pfam00884
431946002471	manganese transport regulator MntR; Provisional; Region: PRK11050
431946002472	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
431946002473	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
431946002474	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
431946002475	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
431946002476	transmembrane helices; other site
431946002477	L,D-transpeptidase; Provisional; Region: PRK10260
431946002478	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
431946002479	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
431946002480	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
431946002481	Walker A/P-loop; other site
431946002482	ATP binding site [chemical binding]; other site
431946002483	Q-loop/lid; other site
431946002484	ABC transporter signature motif; other site
431946002485	Walker B; other site
431946002486	D-loop; other site
431946002487	H-loop/switch region; other site
431946002488	ABC transporter; Region: ABC_tran_2; pfam12848
431946002489	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
431946002490	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
431946002491	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
431946002492	active site
431946002493	motif I; other site
431946002494	motif II; other site
431946002495	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
431946002496	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
431946002497	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
431946002498	dimer interface [polypeptide binding]; other site
431946002499	active site
431946002500	glycine loop; other site
431946002501	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
431946002502	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
431946002503	active site
431946002504	intersubunit interactions; other site
431946002505	catalytic residue [active]
431946002506	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
431946002507	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
431946002508	ATP binding site [chemical binding]; other site
431946002509	substrate interface [chemical binding]; other site
431946002510	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
431946002511	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
431946002512	dimer interface [polypeptide binding]; other site
431946002513	putative functional site; other site
431946002514	putative MPT binding site; other site
431946002515	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
431946002516	catalytic nucleophile [active]
431946002517	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
431946002518	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
431946002519	Walker A/P-loop; other site
431946002520	ATP binding site [chemical binding]; other site
431946002521	Q-loop/lid; other site
431946002522	ABC transporter signature motif; other site
431946002523	Walker B; other site
431946002524	D-loop; other site
431946002525	H-loop/switch region; other site
431946002526	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
431946002527	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
431946002528	Walker A/P-loop; other site
431946002529	ATP binding site [chemical binding]; other site
431946002530	Q-loop/lid; other site
431946002531	ABC transporter signature motif; other site
431946002532	Walker B; other site
431946002533	D-loop; other site
431946002534	H-loop/switch region; other site
431946002535	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
431946002536	glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413
431946002537	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
431946002538	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
431946002539	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946002540	dimer interface [polypeptide binding]; other site
431946002541	conserved gate region; other site
431946002542	putative PBP binding loops; other site
431946002543	ABC-ATPase subunit interface; other site
431946002544	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
431946002545	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
431946002546	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946002547	dimer interface [polypeptide binding]; other site
431946002548	conserved gate region; other site
431946002549	putative PBP binding loops; other site
431946002550	ABC-ATPase subunit interface; other site
431946002551	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
431946002552	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
431946002553	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
431946002554	metal binding site [ion binding]; metal-binding site
431946002555	active site
431946002556	I-site; other site
431946002557	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
431946002558	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
431946002559	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
431946002560	FeS/SAM binding site; other site
431946002561	biofilm formation regulatory protein BssR; Reviewed; Region: bssR; PRK12302
431946002562	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
431946002563	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
431946002564	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
431946002565	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
431946002566	putative C-terminal domain interface [polypeptide binding]; other site
431946002567	putative GSH binding site (G-site) [chemical binding]; other site
431946002568	putative dimer interface [polypeptide binding]; other site
431946002569	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
431946002570	N-terminal domain interface [polypeptide binding]; other site
431946002571	dimer interface [polypeptide binding]; other site
431946002572	substrate binding pocket (H-site) [chemical binding]; other site
431946002573	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
431946002574	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
431946002575	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
431946002576	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
431946002577	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
431946002578	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
431946002579	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
431946002580	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
431946002581	active site
431946002582	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
431946002583	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946002584	putative substrate translocation pore; other site
431946002585	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
431946002586	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
431946002587	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
431946002588	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946002589	putative substrate translocation pore; other site
431946002590	Major Facilitator Superfamily; Region: MFS_1; pfam07690
431946002591	transcriptional repressor BetI; Region: betaine_BetI; TIGR03384
431946002592	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
431946002593	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
431946002594	putative transporter; Provisional; Region: PRK04972
431946002595	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
431946002596	TrkA-C domain; Region: TrkA_C; pfam02080
431946002597	TrkA-C domain; Region: TrkA_C; pfam02080
431946002598	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
431946002599	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
431946002600	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
431946002601	GSH binding site [chemical binding]; other site
431946002602	catalytic residues [active]
431946002603	Protein of unknown function (DUF1418); Region: DUF1418; pfam07214
431946002604	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
431946002605	dimer interface [polypeptide binding]; other site
431946002606	FMN binding site [chemical binding]; other site
431946002607	NADPH bind site [chemical binding]; other site
431946002608	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
431946002609	RimK-like ATP-grasp domain; Region: RimK; pfam08443
431946002610	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
431946002611	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
431946002612	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
431946002613	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
431946002614	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
431946002615	Walker A/P-loop; other site
431946002616	ATP binding site [chemical binding]; other site
431946002617	Q-loop/lid; other site
431946002618	ABC transporter signature motif; other site
431946002619	Walker B; other site
431946002620	D-loop; other site
431946002621	H-loop/switch region; other site
431946002622	TOBE domain; Region: TOBE_2; pfam08402
431946002623	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
431946002624	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946002625	dimer interface [polypeptide binding]; other site
431946002626	conserved gate region; other site
431946002627	putative PBP binding loops; other site
431946002628	ABC-ATPase subunit interface; other site
431946002629	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
431946002630	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946002631	dimer interface [polypeptide binding]; other site
431946002632	conserved gate region; other site
431946002633	putative PBP binding loops; other site
431946002634	ABC-ATPase subunit interface; other site
431946002635	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
431946002636	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
431946002637	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946002638	S-adenosylmethionine binding site [chemical binding]; other site
431946002639	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
431946002640	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
431946002641	substrate binding pocket [chemical binding]; other site
431946002642	membrane-bound complex binding site; other site
431946002643	hinge residues; other site
431946002644	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946002645	dimer interface [polypeptide binding]; other site
431946002646	conserved gate region; other site
431946002647	putative PBP binding loops; other site
431946002648	ABC-ATPase subunit interface; other site
431946002649	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
431946002650	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946002651	dimer interface [polypeptide binding]; other site
431946002652	conserved gate region; other site
431946002653	putative PBP binding loops; other site
431946002654	ABC-ATPase subunit interface; other site
431946002655	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
431946002656	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
431946002657	substrate binding pocket [chemical binding]; other site
431946002658	membrane-bound complex binding site; other site
431946002659	hinge residues; other site
431946002660	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
431946002661	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
431946002662	Walker A/P-loop; other site
431946002663	ATP binding site [chemical binding]; other site
431946002664	Q-loop/lid; other site
431946002665	ABC transporter signature motif; other site
431946002666	Walker B; other site
431946002667	D-loop; other site
431946002668	H-loop/switch region; other site
431946002669	putative lipoprotein; Provisional; Region: PRK10533
431946002670	hypothetical protein; Provisional; Region: PRK02877
431946002671	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
431946002672	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
431946002673	amidase catalytic site [active]
431946002674	Zn binding residues [ion binding]; other site
431946002675	substrate binding site [chemical binding]; other site
431946002676	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
431946002677	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
431946002678	NAD(P) binding site [chemical binding]; other site
431946002679	active site
431946002680	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
431946002681	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
431946002682	putative NAD(P) binding site [chemical binding]; other site
431946002683	putative active site [active]
431946002684	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
431946002685	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
431946002686	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
431946002687	tetramer interface [polypeptide binding]; other site
431946002688	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946002689	catalytic residue [active]
431946002690	pyruvate dehydrogenase; Provisional; Region: PRK09124
431946002691	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
431946002692	PYR/PP interface [polypeptide binding]; other site
431946002693	dimer interface [polypeptide binding]; other site
431946002694	tetramer interface [polypeptide binding]; other site
431946002695	TPP binding site [chemical binding]; other site
431946002696	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
431946002697	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
431946002698	TPP-binding site [chemical binding]; other site
431946002699	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
431946002700	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
431946002701	FAD binding pocket [chemical binding]; other site
431946002702	FAD binding motif [chemical binding]; other site
431946002703	phosphate binding motif [ion binding]; other site
431946002704	beta-alpha-beta structure motif; other site
431946002705	NAD binding pocket [chemical binding]; other site
431946002706	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
431946002707	catalytic loop [active]
431946002708	iron binding site [ion binding]; other site
431946002709	hybrid cluster protein; Provisional; Region: PRK05290
431946002710	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
431946002711	ACS interaction site; other site
431946002712	CODH interaction site; other site
431946002713	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
431946002714	hybrid metal cluster; other site
431946002715	Predicted membrane protein [Function unknown]; Region: COG2431
431946002716	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
431946002717	amphipathic channel; other site
431946002718	Asn-Pro-Ala signature motifs; other site
431946002719	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
431946002720	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
431946002721	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
431946002722	putative active site [active]
431946002723	putative metal-binding site [ion binding]; other site
431946002724	Protein of unknown function (DUF535); Region: DUF535; pfam04393
431946002725	macrolide transporter subunit MacA; Provisional; Region: PRK11578
431946002726	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
431946002727	HlyD family secretion protein; Region: HlyD_3; pfam13437
431946002728	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
431946002729	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
431946002730	Walker A/P-loop; other site
431946002731	ATP binding site [chemical binding]; other site
431946002732	Q-loop/lid; other site
431946002733	ABC transporter signature motif; other site
431946002734	Walker B; other site
431946002735	D-loop; other site
431946002736	H-loop/switch region; other site
431946002737	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
431946002738	FtsX-like permease family; Region: FtsX; pfam02687
431946002739	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
431946002740	DNA-binding site [nucleotide binding]; DNA binding site
431946002741	RNA-binding motif; other site
431946002742	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
431946002743	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
431946002744	Clp amino terminal domain; Region: Clp_N; pfam02861
431946002745	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946002746	Walker A motif; other site
431946002747	ATP binding site [chemical binding]; other site
431946002748	Walker B motif; other site
431946002749	arginine finger; other site
431946002750	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946002751	Walker A motif; other site
431946002752	ATP binding site [chemical binding]; other site
431946002753	Walker B motif; other site
431946002754	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
431946002755	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
431946002756	rRNA binding site [nucleotide binding]; other site
431946002757	predicted 30S ribosome binding site; other site
431946002758	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
431946002759	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
431946002760	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
431946002761	ATP-binding cassette domain of CydCD, subfamily C; Region: ABCC_cytochrome_bd; cd03247
431946002762	Walker A/P-loop; other site
431946002763	ATP binding site [chemical binding]; other site
431946002764	Q-loop/lid; other site
431946002765	ABC transporter signature motif; other site
431946002766	Walker B; other site
431946002767	D-loop; other site
431946002768	H-loop/switch region; other site
431946002769	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
431946002770	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
431946002771	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
431946002772	Walker A/P-loop; other site
431946002773	ATP binding site [chemical binding]; other site
431946002774	Q-loop/lid; other site
431946002775	ABC transporter signature motif; other site
431946002776	Walker B; other site
431946002777	D-loop; other site
431946002778	H-loop/switch region; other site
431946002779	thioredoxin reductase; Provisional; Region: PRK10262
431946002780	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
431946002781	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
431946002782	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
431946002783	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
431946002784	putative DNA binding site [nucleotide binding]; other site
431946002785	putative Zn2+ binding site [ion binding]; other site
431946002786	AsnC family; Region: AsnC_trans_reg; pfam01037
431946002787	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
431946002788	DNA translocase FtsK; Provisional; Region: PRK10263
431946002789	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
431946002790	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
431946002791	periplasmic chaperone LolA; Region: lolA; TIGR00547
431946002792	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
431946002793	recombination factor protein RarA; Reviewed; Region: PRK13342
431946002794	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946002795	Walker A motif; other site
431946002796	ATP binding site [chemical binding]; other site
431946002797	Walker B motif; other site
431946002798	arginine finger; other site
431946002799	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
431946002800	seryl-tRNA synthetase; Provisional; Region: PRK05431
431946002801	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
431946002802	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
431946002803	dimer interface [polypeptide binding]; other site
431946002804	active site
431946002805	motif 1; other site
431946002806	motif 2; other site
431946002807	motif 3; other site
431946002808	anaerobic dimethyl sulfoxide reductase subunit A; Provisional; Region: PRK14990
431946002809	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
431946002810	putative [Fe4-S4] binding site [ion binding]; other site
431946002811	putative molybdopterin cofactor binding site [chemical binding]; other site
431946002812	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
431946002813	putative molybdopterin cofactor binding site; other site
431946002814	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
431946002815	4Fe-4S binding domain; Region: Fer4; pfam00037
431946002816	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
431946002817	Isochorismatase family; Region: Isochorismatase; pfam00857
431946002818	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
431946002819	catalytic triad [active]
431946002820	dimer interface [polypeptide binding]; other site
431946002821	conserved cis-peptide bond; other site
431946002822	putative MFS family transporter protein; Provisional; Region: PRK03633
431946002823	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946002824	putative substrate translocation pore; other site
431946002825	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
431946002826	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
431946002827	FeS/SAM binding site; other site
431946002828	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
431946002829	Pyruvate formate lyase 1; Region: PFL1; cd01678
431946002830	coenzyme A binding site [chemical binding]; other site
431946002831	active site
431946002832	catalytic residues [active]
431946002833	glycine loop; other site
431946002834	formate transporter; Provisional; Region: PRK10805
431946002835	uncharacterized domain; Region: TIGR00702
431946002836	YcaO-like family; Region: YcaO; pfam02624
431946002837	Predicted membrane protein [Function unknown]; Region: COG2323
431946002838	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
431946002839	homodimer interface [polypeptide binding]; other site
431946002840	substrate-cofactor binding pocket; other site
431946002841	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946002842	catalytic residue [active]
431946002843	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
431946002844	Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine enolpyruvyl transferase. Both enzymes catalyze the reaction of enolpyruvyl transfer; Region: EPT-like; cd01554
431946002845	hinge; other site
431946002846	active site
431946002847	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
431946002848	cytidylate kinase; Provisional; Region: cmk; PRK00023
431946002849	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
431946002850	CMP-binding site; other site
431946002851	The sites determining sugar specificity; other site
431946002852	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
431946002853	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
431946002854	RNA binding site [nucleotide binding]; other site
431946002855	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
431946002856	RNA binding site [nucleotide binding]; other site
431946002857	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
431946002858	RNA binding site [nucleotide binding]; other site
431946002859	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
431946002860	RNA binding site [nucleotide binding]; other site
431946002861	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
431946002862	RNA binding site [nucleotide binding]; other site
431946002863	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
431946002864	IHF dimer interface [polypeptide binding]; other site
431946002865	IHF - DNA interface [nucleotide binding]; other site
431946002866	ComEC family competence protein; Provisional; Region: PRK11539
431946002867	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
431946002868	ComEC/Rec2-related protein; Region: ComEC_N-term; TIGR00360
431946002869	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
431946002870	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
431946002871	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
431946002872	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
431946002873	Walker A/P-loop; other site
431946002874	ATP binding site [chemical binding]; other site
431946002875	Q-loop/lid; other site
431946002876	ABC transporter signature motif; other site
431946002877	Walker B; other site
431946002878	D-loop; other site
431946002879	H-loop/switch region; other site
431946002880	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
431946002881	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
431946002882	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3214
431946002883	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
431946002884	hypothetical protein; Provisional; Region: PRK11827
431946002885	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
431946002886	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
431946002887	Ligand binding site; other site
431946002888	oligomer interface; other site
431946002889	hypothetical protein; Provisional; Region: PRK10593
431946002890	Uncharacterized conserved protein [Function unknown]; Region: COG1434
431946002891	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
431946002892	putative active site [active]
431946002893	Methyltransferase domain; Region: Methyltransf_31; pfam13847
431946002894	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946002895	S-adenosylmethionine binding site [chemical binding]; other site
431946002896	condesin subunit F; Provisional; Region: PRK05260
431946002897	condesin subunit E; Provisional; Region: PRK05256
431946002898	Uncharacterized protein involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: MukB; COG3096
431946002899	MukB N-terminal; Region: MukB; pfam04310
431946002900	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
431946002901	murein L,D-transpeptidase; Provisional; Region: PRK10594
431946002902	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
431946002903	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
431946002904	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
431946002905	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
431946002906	Peptidase M15; Region: Peptidase_M15_3; cl01194
431946002907	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
431946002908	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
431946002909	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
431946002910	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946002911	homodimer interface [polypeptide binding]; other site
431946002912	catalytic residue [active]
431946002913	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
431946002914	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
431946002915	trimer interface [polypeptide binding]; other site
431946002916	eyelet of channel; other site
431946002917	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
431946002918	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
431946002919	putative dimer interface [polypeptide binding]; other site
431946002920	putative anticodon binding site; other site
431946002921	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
431946002922	homodimer interface [polypeptide binding]; other site
431946002923	motif 1; other site
431946002924	motif 2; other site
431946002925	active site
431946002926	motif 3; other site
431946002927	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
431946002928	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
431946002929	active site
431946002930	aminopeptidase N; Provisional; Region: pepN; PRK14015
431946002931	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
431946002932	active site
431946002933	Zn binding site [ion binding]; other site
431946002934	aliphatic sulfonates transport ATP-binding subunit; Provisional; Region: ssuB; PRK11247
431946002935	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
431946002936	Walker A/P-loop; other site
431946002937	ATP binding site [chemical binding]; other site
431946002938	Q-loop/lid; other site
431946002939	ABC transporter signature motif; other site
431946002940	Walker B; other site
431946002941	D-loop; other site
431946002942	H-loop/switch region; other site
431946002943	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
431946002944	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946002945	dimer interface [polypeptide binding]; other site
431946002946	conserved gate region; other site
431946002947	putative PBP binding loops; other site
431946002948	ABC-ATPase subunit interface; other site
431946002949	alkanesulfonate monooxygenase; Provisional; Region: PRK00719
431946002950	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
431946002951	active site
431946002952	dimer interface [polypeptide binding]; other site
431946002953	non-prolyl cis peptide bond; other site
431946002954	insertion regions; other site
431946002955	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
431946002956	substrate binding pocket [chemical binding]; other site
431946002957	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
431946002958	membrane-bound complex binding site; other site
431946002959	hinge residues; other site
431946002960	NAD(P)H-dependent FMN reductase; Provisional; Region: PRK10569
431946002961	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
431946002962	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
431946002963	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
431946002964	quinone interaction residues [chemical binding]; other site
431946002965	active site
431946002966	catalytic residues [active]
431946002967	FMN binding site [chemical binding]; other site
431946002968	substrate binding site [chemical binding]; other site
431946002969	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
431946002970	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
431946002971	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
431946002972	MOSC domain; Region: MOSC; pfam03473
431946002973	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
431946002974	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
431946002975	catalytic loop [active]
431946002976	iron binding site [ion binding]; other site
431946002977	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
431946002978	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
431946002979	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
431946002980	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946002981	S-adenosylmethionine binding site [chemical binding]; other site
431946002982	ABC transporter ATPase component; Reviewed; Region: PRK11147
431946002983	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
431946002984	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
431946002985	Walker A/P-loop; other site
431946002986	Walker A/P-loop; other site
431946002987	ATP binding site [chemical binding]; other site
431946002988	ATP binding site [chemical binding]; other site
431946002989	Q-loop/lid; other site
431946002990	Q-loop/lid; other site
431946002991	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
431946002992	ABC transporter signature motif; other site
431946002993	Walker B; other site
431946002994	D-loop; other site
431946002995	ABC transporter; Region: ABC_tran_2; pfam12848
431946002996	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
431946002997	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
431946002998	Paraquat-inducible protein A; Region: PqiA; pfam04403
431946002999	Paraquat-inducible protein A; Region: PqiA; pfam04403
431946003000	paraquat-inducible protein B; Provisional; Region: PRK10807
431946003001	mce related protein; Region: MCE; pfam02470
431946003002	mce related protein; Region: MCE; pfam02470
431946003003	mce related protein; Region: MCE; pfam02470
431946003004	DASH complex subunit Duo1; Region: DASH_Duo1; pfam08651
431946003005	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
431946003006	Protein of unknown function (DUF330); Region: DUF330; pfam03886
431946003007	ribosome modulation factor; Provisional; Region: PRK14563
431946003008	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
431946003009	active site 1 [active]
431946003010	dimer interface [polypeptide binding]; other site
431946003011	active site 2 [active]
431946003012	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
431946003013	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
431946003014	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
431946003015	outer membrane protein A; Reviewed; Region: PRK10808
431946003016	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
431946003017	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
431946003018	ligand binding site [chemical binding]; other site
431946003019	SOS cell division inhibitor; Provisional; Region: PRK10595
431946003020	Regulator of competence-specific genes [Transcription]; Region: TfoX; COG3070
431946003021	TfoX C-terminal domain; Region: TfoX_C; pfam04994
431946003022	TIGR01666 family membrane protein; Region: YCCS
431946003023	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
431946003024	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
431946003025	Predicted membrane protein [Function unknown]; Region: COG3304
431946003026	Domain of unknown function (DUF307); Region: DUF307; pfam03733
431946003027	Domain of unknown function (DUF307); Region: DUF307; pfam03733
431946003028	DNA helicase IV; Provisional; Region: helD; PRK11054
431946003029	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
431946003030	Part of AAA domain; Region: AAA_19; pfam13245
431946003031	Family description; Region: UvrD_C_2; pfam13538
431946003032	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
431946003033	active site
431946003034	dimer interfaces [polypeptide binding]; other site
431946003035	catalytic residues [active]
431946003036	hypothetical protein; Provisional; Region: PRK03641
431946003037	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3110
431946003038	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
431946003039	heat shock protein HspQ; Provisional; Region: PRK14129
431946003040	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
431946003041	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
431946003042	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
431946003043	putative RNA binding site [nucleotide binding]; other site
431946003044	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946003045	S-adenosylmethionine binding site [chemical binding]; other site
431946003046	Acylphosphatase; Region: Acylphosphatase; cl00551
431946003047	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
431946003048	sulfur transfer protein TusE; Provisional; Region: PRK11508
431946003049	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
431946003050	YccA-like proteins; Region: YccA_like; cd10433
431946003051	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
431946003052	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
431946003053	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
431946003054	hydrogenase 1 large subunit; Provisional; Region: PRK10170
431946003055	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
431946003056	hydrogenase 1 b-type cytochrome subunit; Provisional; Region: PRK10171
431946003057	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
431946003058	putative substrate-binding site; other site
431946003059	nickel binding site [ion binding]; other site
431946003060	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
431946003061	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
431946003062	cytochrome bd-II oxidase subunit 1; Provisional; Region: PRK15035
431946003063	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
431946003064	cytochrome bd-II oxidase subunit 2; Provisional; Region: PRK15028
431946003065	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
431946003066	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
431946003067	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
431946003068	catalytic core [active]
431946003069	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
431946003070	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
431946003071	DNA-binding site [nucleotide binding]; DNA binding site
431946003072	RNA-binding motif; other site
431946003073	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
431946003074	DNA-binding site [nucleotide binding]; DNA binding site
431946003075	RNA-binding motif; other site
431946003076	cold shock gene; Provisional; Region: PRK09891
431946003077	GnsA/GnsB family; Region: GnsAB; pfam08178
431946003078	4Fe-4S binding domain; Region: Fer4_5; pfam12801
431946003079	4Fe-4S binding domain; Region: Fer4_5; pfam12801
431946003080	Ferredoxin [Energy production and conversion]; Region: NapF; COG1145
431946003081	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
431946003082	4Fe-4S dicluster domain; Region: Fer4_10; pfam13237
431946003083	hybrid sensory histidine kinase TorS; Provisional; Region: PRK11466
431946003084	HAMP domain; Region: HAMP; pfam00672
431946003085	dimerization interface [polypeptide binding]; other site
431946003086	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
431946003087	dimer interface [polypeptide binding]; other site
431946003088	phosphorylation site [posttranslational modification]
431946003089	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946003090	ATP binding site [chemical binding]; other site
431946003091	Mg2+ binding site [ion binding]; other site
431946003092	G-X-G motif; other site
431946003093	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946003094	active site
431946003095	phosphorylation site [posttranslational modification]
431946003096	intermolecular recognition site; other site
431946003097	dimerization interface [polypeptide binding]; other site
431946003098	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
431946003099	putative binding surface; other site
431946003100	active site
431946003101	TMAO reductase system periplasmic protein TorT; Provisional; Region: PRK10936
431946003102	TorT-like proteins, a periplasmic binding protein family that activates induction of the Tor respiratory system upon trimethylamine N-oxide (TMAO) electron-acceptor binding in bacteria; Region: PBP1_TorT-like; cd06306
431946003103	putative ligand binding site [chemical binding]; other site
431946003104	DNA-binding transcriptional regulator TorR; Provisional; Region: PRK10766
431946003105	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946003106	active site
431946003107	phosphorylation site [posttranslational modification]
431946003108	intermolecular recognition site; other site
431946003109	dimerization interface [polypeptide binding]; other site
431946003110	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
431946003111	DNA binding site [nucleotide binding]
431946003112	trimethylamine N-oxide reductase cytochrome c-type subunit; Provisional; Region: PRK15032
431946003113	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
431946003114	trimethylamine N-oxide reductase I catalytic subunit; Provisional; Region: PRK15102
431946003115	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
431946003116	molybdopterin cofactor binding site [chemical binding]; other site
431946003117	substrate binding site [chemical binding]; other site
431946003118	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
431946003119	molybdopterin cofactor binding site; other site
431946003120	chaperone protein TorD; Validated; Region: torD; PRK04976
431946003121	chaperone-modulator protein CbpM; Provisional; Region: PRK10265
431946003122	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
431946003123	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
431946003124	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
431946003125	HSP70 interaction site [polypeptide binding]; other site
431946003126	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
431946003127	substrate binding site [polypeptide binding]; other site
431946003128	dimer interface [polypeptide binding]; other site
431946003129	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
431946003130	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
431946003131	catalytic core [active]
431946003132	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
431946003133	hypothetical protein; Provisional; Region: PRK10174
431946003134	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
431946003135	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
431946003136	General stress protein [General function prediction only]; Region: GsiB; COG3729
431946003137	pyrimidine utilization transport protein G; Region: RutG; TIGR03616
431946003138	pyrimidine utilization flavin reductase protein F; Region: RutF; TIGR03615
431946003139	Nitroreductase-like family 5.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_5; cd02148
431946003140	putative FMN binding site [chemical binding]; other site
431946003141	pyrimidine utilization protein D; Region: RutD; TIGR03611
431946003142	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
431946003143	homotrimer interaction site [polypeptide binding]; other site
431946003144	putative active site [active]
431946003145	Isochorismatase family; Region: Isochorismatase; pfam00857
431946003146	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
431946003147	catalytic triad [active]
431946003148	conserved cis-peptide bond; other site
431946003149	pyrimidine utilization protein A; Region: RutA; TIGR03612
431946003150	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
431946003151	active site
431946003152	dimer interface [polypeptide binding]; other site
431946003153	non-prolyl cis peptide bond; other site
431946003154	insertion regions; other site
431946003155	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
431946003156	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
431946003157	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
431946003158	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
431946003159	Predicted transcriptional regulator [Transcription]; Region: COG3905
431946003160	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
431946003161	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
431946003162	Glutamate binding site [chemical binding]; other site
431946003163	NAD binding site [chemical binding]; other site
431946003164	catalytic residues [active]
431946003165	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
431946003166	Na binding site [ion binding]; other site
431946003167	FTR1 family protein; Region: TIGR00145
431946003168	inactive ferrous ion transporter periplasmic protein EfeO; Provisional; Region: PRK10378
431946003169	Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473
431946003170	Imelysin; Region: Peptidase_M75; pfam09375
431946003171	Tat-translocated enzyme; Region: tat_substr_1; TIGR01412
431946003172	Predicted iron-dependent peroxidase [Inorganic ion transport and metabolism]; Region: COG2837
431946003173	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
431946003174	hypothetical protein; Provisional; Region: PRK10536
431946003175	putative PGA biosynthesis protein; Provisional; Region: pgaD; PRK14585
431946003176	N-glycosyltransferase; Provisional; Region: PRK11204
431946003177	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
431946003178	DXD motif; other site
431946003179	Glycosyl transferase family group 2; Region: Glyco_trans_2_3; pfam13632
431946003180	outer membrane N-deacetylase; Provisional; Region: pgaB; PRK14582
431946003181	N-terminal putative catalytic polysaccharide deacetylase domain of bacterial poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB, and similar proteins; Region: CE4_PgaB_5s; cd10964
431946003182	putative active site [active]
431946003183	putative metal binding site [ion binding]; other site
431946003184	outer membrane protein PgaA; Provisional; Region: pgaA; PRK10049
431946003185	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
431946003186	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
431946003187	metal binding site [ion binding]; metal-binding site
431946003188	active site
431946003189	I-site; other site
431946003190	bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469
431946003191	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
431946003192	putative ligand binding site [chemical binding]; other site
431946003193	NAD binding site [chemical binding]; other site
431946003194	dimerization interface [polypeptide binding]; other site
431946003195	catalytic site [active]
431946003196	putative hydrolase; Validated; Region: PRK09248
431946003197	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
431946003198	active site
431946003199	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
431946003200	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
431946003201	curli production assembly/transport protein CsgG; Provisional; Region: PRK15184
431946003202	curli assembly protein CsgF; Provisional; Region: PRK10050
431946003203	curli assembly protein CsgE; Provisional; Region: PRK10386
431946003204	DNA-binding transcriptional regulator CsgD; Provisional; Region: PRK10100
431946003205	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
431946003206	DNA binding residues [nucleotide binding]
431946003207	dimerization interface [polypeptide binding]; other site
431946003208	curlin minor subunit CsgB; Provisional; Region: csgB; PRK10101
431946003209	Curlin associated repeat; Region: Curlin_rpt; pfam07012
431946003210	Curlin associated repeat; Region: Curlin_rpt; pfam07012
431946003211	major curlin subunit; Provisional; Region: csgA; PRK10051
431946003212	Curlin associated repeat; Region: Curlin_rpt; pfam07012
431946003213	Curlin associated repeat; Region: Curlin_rpt; pfam07012
431946003214	curli assembly protein CsgC; Provisional; Region: csgC; PRK10102
431946003215	Fimbrial protein; Region: Fimbrial; cl01416
431946003216	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
431946003217	putative ADP-ribose binding site [chemical binding]; other site
431946003218	putative active site [active]
431946003219	Phosphatidylserine/phosphatidylglycerophosphate/car diolipin synthases and related enzymes [Lipid metabolism]; Region: Cls; COG1502
431946003220	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
431946003221	putative active site [active]
431946003222	catalytic site [active]
431946003223	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
431946003224	putative active site [active]
431946003225	catalytic site [active]
431946003226	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
431946003227	Acyltransferase family; Region: Acyl_transf_3; pfam01757
431946003228	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
431946003229	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; pfam04349
431946003230	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
431946003231	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
431946003232	Ligand binding site; other site
431946003233	DXD motif; other site
431946003234	lipoprotein; Provisional; Region: PRK10175
431946003235	secY/secA suppressor protein; Provisional; Region: PRK11467
431946003236	drug efflux system protein MdtG; Provisional; Region: PRK09874
431946003237	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946003238	putative substrate translocation pore; other site
431946003239	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
431946003240	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
431946003241	putative acyl-acceptor binding pocket; other site
431946003242	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
431946003243	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
431946003244	active site residue [active]
431946003245	hypothetical protein; Provisional; Region: PRK03757
431946003246	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
431946003247	Protein of unknown function (DUF2770); Region: DUF2770; pfam10968
431946003248	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
431946003249	hydroxyglutarate oxidase; Provisional; Region: PRK11728
431946003250	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
431946003251	DNA damage-inducible protein I; Provisional; Region: PRK10597
431946003252	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
431946003253	active site
431946003254	substrate binding pocket [chemical binding]; other site
431946003255	dimer interface [polypeptide binding]; other site
431946003256	lipoprotein; Provisional; Region: PRK10598
431946003257	glutaredoxin 2; Provisional; Region: PRK10387
431946003258	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
431946003259	C-terminal domain interface [polypeptide binding]; other site
431946003260	GSH binding site (G-site) [chemical binding]; other site
431946003261	catalytic residues [active]
431946003262	putative dimer interface [polypeptide binding]; other site
431946003263	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
431946003264	N-terminal domain interface [polypeptide binding]; other site
431946003265	multidrug resistance protein MdtH; Provisional; Region: PRK11646
431946003266	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946003267	putative substrate translocation pore; other site
431946003268	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
431946003269	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
431946003270	hypothetical protein; Provisional; Region: PRK11239
431946003271	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3132
431946003272	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
431946003273	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
431946003274	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
431946003275	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
431946003276	MviN-like protein; Region: MVIN; pfam03023
431946003277	flagella synthesis chaperone protein FlgN; Provisional; Region: PRK15459
431946003278	anti-sigma28 factor FlgM; Provisional; Region: PRK10810
431946003279	Flagellar basal body P-ring biosynthesis protein [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FlgA; COG1261
431946003280	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
431946003281	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
431946003282	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
431946003283	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
431946003284	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
431946003285	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
431946003286	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
431946003287	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06655
431946003288	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
431946003289	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
431946003290	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
431946003291	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
431946003292	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
431946003293	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
431946003294	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgF; COG4787
431946003295	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
431946003296	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
431946003297	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
431946003298	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
431946003299	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
431946003300	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
431946003301	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
431946003302	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
431946003303	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
431946003304	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
431946003305	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
431946003306	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
431946003307	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
431946003308	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
431946003309	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
431946003310	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
431946003311	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
431946003312	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
431946003313	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
431946003314	homodimer interface [polypeptide binding]; other site
431946003315	oligonucleotide binding site [chemical binding]; other site
431946003316	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
431946003317	Protein of unknown function (DUF2655); Region: DUF2655; pfam10848
431946003318	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
431946003319	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
431946003320	RNA binding surface [nucleotide binding]; other site
431946003321	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
431946003322	active site
431946003323	Maf-like protein; Region: Maf; pfam02545
431946003324	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
431946003325	active site
431946003326	dimer interface [polypeptide binding]; other site
431946003327	hypothetical protein; Provisional; Region: PRK11193
431946003328	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
431946003329	putative phosphate acyltransferase; Provisional; Region: PRK05331
431946003330	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
431946003331	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
431946003332	dimer interface [polypeptide binding]; other site
431946003333	active site
431946003334	CoA binding pocket [chemical binding]; other site
431946003335	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
431946003336	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
431946003337	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
431946003338	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
431946003339	NAD(P) binding site [chemical binding]; other site
431946003340	homotetramer interface [polypeptide binding]; other site
431946003341	homodimer interface [polypeptide binding]; other site
431946003342	active site
431946003343	acyl carrier protein; Provisional; Region: acpP; PRK00982
431946003344	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
431946003345	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
431946003346	dimer interface [polypeptide binding]; other site
431946003347	active site
431946003348	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
431946003349	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
431946003350	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946003351	catalytic residue [active]
431946003352	conserved hypothetical protein, YceG family; Region: TIGR00247
431946003353	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
431946003354	dimerization interface [polypeptide binding]; other site
431946003355	thymidylate kinase; Validated; Region: tmk; PRK00698
431946003356	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
431946003357	TMP-binding site; other site
431946003358	ATP-binding site [chemical binding]; other site
431946003359	DNA polymerase III subunit delta'; Validated; Region: PRK07993
431946003360	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
431946003361	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
431946003362	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
431946003363	active site
431946003364	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
431946003365	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
431946003366	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
431946003367	active site turn [active]
431946003368	phosphorylation site [posttranslational modification]
431946003369	ferric-rhodotorulic acid outer membrane transporter; Provisional; Region: PRK10003
431946003370	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
431946003371	N-terminal plug; other site
431946003372	ligand-binding site [chemical binding]; other site
431946003373	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
431946003374	nucleotide binding site/active site [active]
431946003375	HIT family signature motif; other site
431946003376	catalytic residue [active]
431946003377	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
431946003378	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
431946003379	putative dimer interface [polypeptide binding]; other site
431946003380	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
431946003381	thiamine kinase; Region: ycfN_thiK; TIGR02721
431946003382	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
431946003383	active site
431946003384	substrate binding site [chemical binding]; other site
431946003385	ATP binding site [chemical binding]; other site
431946003386	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
431946003387	beta-hexosaminidase; Provisional; Region: PRK05337
431946003388	hypothetical protein; Provisional; Region: PRK04940
431946003389	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
431946003390	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
431946003391	hypothetical protein; Provisional; Region: PRK11280
431946003392	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
431946003393	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
431946003394	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
431946003395	L,D-transpeptidase; Provisional; Region: PRK10260
431946003396	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
431946003397	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
431946003398	transcription-repair coupling factor; Provisional; Region: PRK10689
431946003399	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
431946003400	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
431946003401	ATP binding site [chemical binding]; other site
431946003402	putative Mg++ binding site [ion binding]; other site
431946003403	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
431946003404	nucleotide binding region [chemical binding]; other site
431946003405	ATP-binding site [chemical binding]; other site
431946003406	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
431946003407	Predicted membrane protein [Function unknown]; Region: COG4763
431946003408	Acyltransferase family; Region: Acyl_transf_3; pfam01757
431946003409	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
431946003410	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
431946003411	FtsX-like permease family; Region: FtsX; pfam02687
431946003412	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
431946003413	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
431946003414	Walker A/P-loop; other site
431946003415	ATP binding site [chemical binding]; other site
431946003416	Q-loop/lid; other site
431946003417	ABC transporter signature motif; other site
431946003418	Walker B; other site
431946003419	D-loop; other site
431946003420	H-loop/switch region; other site
431946003421	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
431946003422	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
431946003423	FtsX-like permease family; Region: FtsX; pfam02687
431946003424	fructokinase; Reviewed; Region: PRK09557
431946003425	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
431946003426	nucleotide binding site [chemical binding]; other site
431946003427	NAD-dependent deacetylase; Provisional; Region: PRK00481
431946003428	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
431946003429	NAD+ binding site [chemical binding]; other site
431946003430	substrate binding site [chemical binding]; other site
431946003431	Zn binding site [ion binding]; other site
431946003432	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
431946003433	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
431946003434	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
431946003435	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
431946003436	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946003437	dimer interface [polypeptide binding]; other site
431946003438	conserved gate region; other site
431946003439	putative PBP binding loops; other site
431946003440	ABC-ATPase subunit interface; other site
431946003441	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
431946003442	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946003443	dimer interface [polypeptide binding]; other site
431946003444	conserved gate region; other site
431946003445	putative PBP binding loops; other site
431946003446	ABC-ATPase subunit interface; other site
431946003447	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
431946003448	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
431946003449	Walker A/P-loop; other site
431946003450	ATP binding site [chemical binding]; other site
431946003451	Q-loop/lid; other site
431946003452	ABC transporter signature motif; other site
431946003453	Walker B; other site
431946003454	D-loop; other site
431946003455	H-loop/switch region; other site
431946003456	TOBE domain; Region: TOBE_2; pfam08402
431946003457	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
431946003458	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
431946003459	metal binding site [ion binding]; metal-binding site
431946003460	dimer interface [polypeptide binding]; other site
431946003461	Uncharacterized conserved protein [Function unknown]; Region: COG2850
431946003462	Cupin-like domain; Region: Cupin_8; pfam13621
431946003463	sensor protein PhoQ; Provisional; Region: PRK10815
431946003464	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
431946003465	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
431946003466	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
431946003467	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946003468	ATP binding site [chemical binding]; other site
431946003469	Mg2+ binding site [ion binding]; other site
431946003470	G-X-G motif; other site
431946003471	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
431946003472	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946003473	active site
431946003474	phosphorylation site [posttranslational modification]
431946003475	intermolecular recognition site; other site
431946003476	dimerization interface [polypeptide binding]; other site
431946003477	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
431946003478	DNA binding site [nucleotide binding]
431946003479	adenylosuccinate lyase; Provisional; Region: PRK09285
431946003480	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
431946003481	tetramer interface [polypeptide binding]; other site
431946003482	active site
431946003483	putative lysogenization regulator; Reviewed; Region: PRK00218
431946003484	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
431946003485	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
431946003486	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
431946003487	nudix motif; other site
431946003488	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
431946003489	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
431946003490	probable active site [active]
431946003491	isocitrate dehydrogenase; Validated; Region: PRK07362
431946003492	isocitrate dehydrogenase; Reviewed; Region: PRK07006
431946003493	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
431946003494	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
431946003495	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
431946003496	dimer interface [polypeptide binding]; other site
431946003497	active site
431946003498	Int/Topo IB signature motif; other site
431946003499	Domain of unknown function (DUF4222); Region: DUF4222; pfam13973
431946003500	DksA-like zinc finger domain containing protein; Region: PHA00080
431946003501	Protein of unknown function (DUF1382); Region: DUF1382; pfam07131
431946003502	Protein of unknown function (DUF1317); Region: DUF1317; pfam07026
431946003503	YqaJ-like viral recombinase domain; Region: YqaJ; pfam09588
431946003504	phage recombination protein Bet; Region: bet_lambda; TIGR01913
431946003505	Host-nuclease inhibitor protein Gam; Region: Gam; pfam06064
431946003506	Uncharacterized conserved protein [Function unknown]; Region: COG4933
431946003507	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
431946003508	non-specific DNA binding site [nucleotide binding]; other site
431946003509	Predicted transcriptional regulator [Transcription]; Region: COG2932
431946003510	salt bridge; other site
431946003511	sequence-specific DNA binding site [nucleotide binding]; other site
431946003512	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
431946003513	Catalytic site [active]
431946003514	Uncharacterized protein conserved in bacteria, prophage-related [Function unknown]; Region: COG4197
431946003515	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
431946003516	Bacteriophage replication protein O; Region: Phage_rep_O; pfam04492
431946003517	Replication protein P; Region: Phage_lambda_P; pfam06992
431946003518	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
431946003519	putative Zn2+ binding site [ion binding]; other site
431946003520	putative DNA binding site [nucleotide binding]; other site
431946003521	multidrug efflux protein; Reviewed; Region: emrE; PRK09541
431946003522	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
431946003523	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
431946003524	catalytic residues [active]
431946003525	catalytic nucleophile [active]
431946003526	Recombinase; Region: Recombinase; pfam07508
431946003527	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
431946003528	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
431946003529	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
431946003530	hypothetical protein; Provisional; Region: PRK09741
431946003531	prophage protein NinE; Provisional; Region: PRK09689
431946003532	Protein of unknown function (DUF1364); Region: DUF1364; pfam07102
431946003533	endodeoxyribonuclease RUS; Reviewed; Region: PRK09786
431946003534	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
431946003535	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
431946003536	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
431946003537	trimer interface [polypeptide binding]; other site
431946003538	eyelet of channel; other site
431946003539	Lysis protein S; Region: Lysis_S; pfam04971
431946003540	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
431946003541	catalytic residues [active]
431946003542	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
431946003543	Phage DNA packaging protein Nu1; Region: Phage_Nu1; pfam07471
431946003544	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
431946003545	gpW; Region: gpW; pfam02831
431946003546	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
431946003547	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
431946003548	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
431946003549	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
431946003550	tandem repeat interface [polypeptide binding]; other site
431946003551	oligomer interface [polypeptide binding]; other site
431946003552	active site residues [active]
431946003553	Bacteriophage lambda head decoration protein D; Region: HDPD; pfam02924
431946003554	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
431946003555	DNA packaging protein FI; Region: Packaging_FI; pfam14000
431946003556	Phage Head-Tail Attachment; Region: Phage_attach; pfam05354
431946003557	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
431946003558	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
431946003559	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
431946003560	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
431946003561	phage minor tail protein G; Region: phage_lambda_G; TIGR01674
431946003562	Minor tail protein T; Region: Phage_tail_T; pfam06223
431946003563	Phage-related minor tail protein [Function unknown]; Region: COG5281
431946003564	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
431946003565	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
431946003566	Phage-related protein [Function unknown]; Region: COG4718
431946003567	Phage-related protein [Function unknown]; Region: gp18; COG4672
431946003568	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
431946003569	MPN+ (JAMM) motif; other site
431946003570	Zinc-binding site [ion binding]; other site
431946003571	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
431946003572	NlpC/P60 family; Region: NLPC_P60; cl17555
431946003573	Phage-related protein, tail component [Function unknown]; Region: COG4723
431946003574	Phage-related protein, tail component [Function unknown]; Region: COG4733
431946003575	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
431946003576	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
431946003577	DNA binding residues [nucleotide binding]
431946003578	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
431946003579	Integrase core domain; Region: rve; pfam00665
431946003580	DNA replication protein [DNA replication, recombination, and repair]; Region: DnaC; COG1484
431946003581	IstB-like ATP binding N-terminal; Region: IstB_IS21_ATP; pfam08483
431946003582	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946003583	Walker A motif; other site
431946003584	ATP binding site [chemical binding]; other site
431946003585	Phage-related protein, tail component [Function unknown]; Region: COG4733
431946003586	Putative phage tail protein; Region: Phage-tail_3; pfam13550
431946003587	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
431946003588	Fibronectin type III protein; Region: DUF3672; pfam12421
431946003589	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
431946003590	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
431946003591	Transposase; Region: HTH_Tnp_1; pfam01527
431946003592	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
431946003593	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
431946003594	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
431946003595	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
431946003596	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
431946003597	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
431946003598	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
431946003599	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
431946003600	ABC-ATPase subunit  interface; other site
431946003601	dimer interface [polypeptide binding]; other site
431946003602	putative PBP binding regions; other site
431946003603	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
431946003604	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
431946003605	ABC-ATPase subunit  interface; other site
431946003606	dimer interface [polypeptide binding]; other site
431946003607	putative PBP binding regions; other site
431946003608	manganese/iron transporter ATP-binding protein; Provisional; Region: PRK15056
431946003609	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
431946003610	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
431946003611	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
431946003612	metal binding site [ion binding]; metal-binding site
431946003613	Protein of unknown function (DUF1398); Region: DUF1398; pfam07166
431946003614	transcriptional regulator MirA; Provisional; Region: PRK15043
431946003615	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
431946003616	DNA binding residues [nucleotide binding]
431946003617	Sensors of blue-light using FAD; Region: BLUF; smart01034
431946003618	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
431946003619	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
431946003620	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
431946003621	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
431946003622	Autotransporter beta-domain; Region: Autotransporter; smart00869
431946003623	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
431946003624	cell division inhibitor MinD; Provisional; Region: PRK10818
431946003625	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
431946003626	Switch I; other site
431946003627	Switch II; other site
431946003628	septum formation inhibitor; Reviewed; Region: minC; PRK03511
431946003629	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
431946003630	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
431946003631	Fels-1 Prophage Protein-like; Region: Fels1; pfam05666
431946003632	Fels-1 Prophage Protein-like; Region: Fels1; pfam05666
431946003633	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
431946003634	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
431946003635	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
431946003636	hypothetical protein; Provisional; Region: PRK10691
431946003637	hypothetical protein; Provisional; Region: PRK05170
431946003638	Haemolysin E (HlyE); Region: HlyE; cl11627
431946003639	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
431946003640	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
431946003641	Catalytic site [active]
431946003642	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
431946003643	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
431946003644	active site
431946003645	DNA binding site [nucleotide binding]
431946003646	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
431946003647	disulfide bond formation protein B; Provisional; Region: PRK01749
431946003648	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
431946003649	transmembrane helices; other site
431946003650	fatty acid metabolism regulator; Provisional; Region: PRK04984
431946003651	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
431946003652	DNA-binding site [nucleotide binding]; DNA binding site
431946003653	FadR C-terminal domain; Region: FadR_C; pfam07840
431946003654	SpoVR family protein; Provisional; Region: PRK11767
431946003655	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
431946003656	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
431946003657	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
431946003658	alanine racemase; Reviewed; Region: dadX; PRK03646
431946003659	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
431946003660	active site
431946003661	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
431946003662	substrate binding site [chemical binding]; other site
431946003663	catalytic residues [active]
431946003664	dimer interface [polypeptide binding]; other site
431946003665	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
431946003666	TrkA-C domain; Region: TrkA_C; pfam02080
431946003667	Transporter associated domain; Region: CorC_HlyC; smart01091
431946003668	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
431946003669	dimer interface [polypeptide binding]; other site
431946003670	catalytic triad [active]
431946003671	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
431946003672	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
431946003673	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
431946003674	N-acetyl-D-glucosamine binding site [chemical binding]; other site
431946003675	catalytic residue [active]
431946003676	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
431946003677	Flagellar regulator YcgR; Region: YcgR; pfam07317
431946003678	PilZ domain; Region: PilZ; pfam07238
431946003679	hypothetical protein; Provisional; Region: PRK10457
431946003680	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
431946003681	N-terminal plug; other site
431946003682	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
431946003683	ligand-binding site [chemical binding]; other site
431946003684	molybdenum transport protein ModD; Provisional; Region: PRK06096
431946003685	ModD; Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase) present in some modABC operons in bacteria, which are involved in molybdate transport. In general, QPRTases are part of the de novo synthesis pathway of NAD in both prokaryotes and...; Region: modD_like; cd01573
431946003686	dimerization interface [polypeptide binding]; other site
431946003687	active site
431946003688	Methyltransferase domain; Region: Methyltransf_31; pfam13847
431946003689	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946003690	S-adenosylmethionine binding site [chemical binding]; other site
431946003691	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
431946003692	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
431946003693	Walker A/P-loop; other site
431946003694	ATP binding site [chemical binding]; other site
431946003695	Q-loop/lid; other site
431946003696	ABC transporter signature motif; other site
431946003697	Walker B; other site
431946003698	D-loop; other site
431946003699	H-loop/switch region; other site
431946003700	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
431946003701	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
431946003702	ABC-ATPase subunit  interface; other site
431946003703	dimer interface [polypeptide binding]; other site
431946003704	putative PBP binding regions; other site
431946003705	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
431946003706	Metal binding protein HemV-2.  These proteins are predicted to function as initial receptors in ABC transport of metal ions.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding...; Region: HemV-2; cd01147
431946003707	putative metal binding site [ion binding]; other site
431946003708	trehalase; Provisional; Region: treA; PRK13271
431946003709	Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626
431946003710	dihydroxyacetone kinase subunit M; Provisional; Region: PRK11377
431946003711	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3412
431946003712	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
431946003713	dimerization domain swap beta strand [polypeptide binding]; other site
431946003714	regulatory protein interface [polypeptide binding]; other site
431946003715	active site
431946003716	regulatory phosphorylation site [posttranslational modification]; other site
431946003717	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
431946003718	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
431946003719	dihydroxyacetone kinase subunit DhaL; Provisional; Region: PRK10005
431946003720	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK11468
431946003721	Dak1 domain; Region: Dak1; pfam02733
431946003722	DNA-binding transcriptional regulator DhaR; Provisional; Region: PRK11388
431946003723	PAS domain; Region: PAS; smart00091
431946003724	putative active site [active]
431946003725	heme pocket [chemical binding]; other site
431946003726	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946003727	Walker A motif; other site
431946003728	ATP binding site [chemical binding]; other site
431946003729	Walker B motif; other site
431946003730	arginine finger; other site
431946003731	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
431946003732	Probable pectinesterase/pectinesterase inhibitor; Region: PLN02708
431946003733	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
431946003734	RT_Bac_retron_II: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_II; cd03487
431946003735	putative active site [active]
431946003736	putative NTP binding site [chemical binding]; other site
431946003737	putative nucleic acid binding site [nucleotide binding]; other site
431946003738	Restriction endonuclease; Region: Mrr_cat; pfam04471
431946003739	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419
431946003740	Winged helix-turn-helix DNA-binding; Region: HTH_35; cl17423
431946003741	Protein of unknown function (DUF2787); Region: DUF2787; pfam10980
431946003742	hypothetical protein; Reviewed; Region: PRK00024
431946003743	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
431946003744	MPN+ (JAMM) motif; other site
431946003745	Zinc-binding site [ion binding]; other site
431946003746	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
431946003747	active site
431946003748	catalytic residues [active]
431946003749	DNA binding site [nucleotide binding]
431946003750	Int/Topo IB signature motif; other site
431946003751	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
431946003752	Helix-turn-helix domain; Region: HTH_38; pfam13936
431946003753	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
431946003754	Predicted membrane protein (DUF2339); Region: DUF2339; pfam10101
431946003755	Protein of unknown function (DUF3999); Region: DUF3999; pfam13163
431946003756	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
431946003757	putative transposase OrfB; Reviewed; Region: PHA02517
431946003758	HTH-like domain; Region: HTH_21; pfam13276
431946003759	Integrase core domain; Region: rve; pfam00665
431946003760	Integrase core domain; Region: rve_2; pfam13333
431946003761	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
431946003762	Transposase; Region: HTH_Tnp_1; pfam01527
431946003763	integrase; Provisional; Region: PRK09692
431946003764	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
431946003765	active site
431946003766	Int/Topo IB signature motif; other site
431946003767	GTP-binding protein YchF; Reviewed; Region: PRK09601
431946003768	YchF GTPase; Region: YchF; cd01900
431946003769	G1 box; other site
431946003770	GTP/Mg2+ binding site [chemical binding]; other site
431946003771	Switch I region; other site
431946003772	G2 box; other site
431946003773	Switch II region; other site
431946003774	G3 box; other site
431946003775	G4 box; other site
431946003776	G5 box; other site
431946003777	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
431946003778	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
431946003779	putative active site [active]
431946003780	catalytic residue [active]
431946003781	hypothetical protein; Provisional; Region: PRK10692
431946003782	putative transporter; Provisional; Region: PRK11660
431946003783	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
431946003784	Sulfate transporter family; Region: Sulfate_transp; pfam00916
431946003785	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
431946003786	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
431946003787	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
431946003788	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
431946003789	active site
431946003790	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
431946003791	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
431946003792	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
431946003793	outer membrane lipoprotein LolB; Region: lolB; TIGR00548
431946003794	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
431946003795	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
431946003796	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
431946003797	tRNA; other site
431946003798	putative tRNA binding site [nucleotide binding]; other site
431946003799	putative NADP binding site [chemical binding]; other site
431946003800	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
431946003801	peptide chain release factor 1; Validated; Region: prfA; PRK00591
431946003802	This domain is found in peptide chain release factors; Region: PCRF; smart00937
431946003803	RF-1 domain; Region: RF-1; pfam00472
431946003804	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
431946003805	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946003806	hypothetical protein; Provisional; Region: PRK10278
431946003807	hypothetical protein; Provisional; Region: PRK10941
431946003808	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
431946003809	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
431946003810	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
431946003811	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
431946003812	calcium/sodium:proton antiporter; Provisional; Region: PRK10599
431946003813	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
431946003814	cation transport regulator; Reviewed; Region: chaB; PRK09582
431946003815	Uncharacterized protein involved in cation transport [Inorganic ion transport and metabolism]; Region: ChaC; COG3703
431946003816	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
431946003817	putative active site pocket [active]
431946003818	dimerization interface [polypeptide binding]; other site
431946003819	putative catalytic residue [active]
431946003820	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
431946003821	putative invasin; Provisional; Region: PRK10177
431946003822	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
431946003823	transcriptional regulator NarL; Provisional; Region: PRK10651
431946003824	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946003825	active site
431946003826	phosphorylation site [posttranslational modification]
431946003827	intermolecular recognition site; other site
431946003828	dimerization interface [polypeptide binding]; other site
431946003829	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
431946003830	DNA binding residues [nucleotide binding]
431946003831	dimerization interface [polypeptide binding]; other site
431946003832	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
431946003833	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
431946003834	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
431946003835	dimerization interface [polypeptide binding]; other site
431946003836	Histidine kinase; Region: HisKA_3; pfam07730
431946003837	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946003838	ATP binding site [chemical binding]; other site
431946003839	Mg2+ binding site [ion binding]; other site
431946003840	G-X-G motif; other site
431946003841	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
431946003842	respiratory nitrate reductase, alpha subunit; Region: narG; TIGR01580
431946003843	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
431946003844	[4Fe-4S] binding site [ion binding]; other site
431946003845	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
431946003846	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
431946003847	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
431946003848	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
431946003849	molybdopterin cofactor binding site; other site
431946003850	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
431946003851	4Fe-4S binding domain; Region: Fer4; cl02805
431946003852	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
431946003853	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
431946003854	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK07204
431946003855	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
431946003856	dimer interface [polypeptide binding]; other site
431946003857	active site
431946003858	CoA binding pocket [chemical binding]; other site
431946003859	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
431946003860	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
431946003861	NAD(P) binding site [chemical binding]; other site
431946003862	active site
431946003863	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
431946003864	Coenzyme F390 synthetase [Coenzyme metabolism]; Region: PaaK; COG1541
431946003865	putative adenylate-forming enzyme; Region: aden_form_hyp; TIGR02304
431946003866	PAP2_like proteins, Aur1_like subfamily. Yeast Aur1p or Ipc1p is necessary for the addition of inositol phosphate to ceramide, an essential step in yeast sphingolipid synthesis, and is the target of several antifungal compounds such as aureobasidin; Region: PAP2_Aur1_like; cd03386
431946003867	active site
431946003868	Sterol desaturase [Lipid metabolism]; Region: ERG3; COG3000
431946003869	Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; pfam04116
431946003870	The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases...; Region: Delta6-FADS-like; cd03506
431946003871	putative di-iron ligands [ion binding]; other site
431946003872	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
431946003873	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
431946003874	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
431946003875	putative active site [active]
431946003876	putative substrate binding site [chemical binding]; other site
431946003877	putative cosubstrate binding site; other site
431946003878	catalytic site [active]
431946003879	SEC-C motif; Region: SEC-C; pfam02810
431946003880	hypothetical protein; Provisional; Region: PRK04233
431946003881	hypothetical protein; Provisional; Region: PRK10279
431946003882	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
431946003883	active site
431946003884	nucleophile elbow; other site
431946003885	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946003886	active site
431946003887	response regulator of RpoS; Provisional; Region: PRK10693
431946003888	phosphorylation site [posttranslational modification]
431946003889	intermolecular recognition site; other site
431946003890	dimerization interface [polypeptide binding]; other site
431946003891	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
431946003892	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
431946003893	active site
431946003894	tetramer interface; other site
431946003895	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
431946003896	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
431946003897	thymidine kinase; Provisional; Region: PRK04296
431946003898	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
431946003899	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
431946003900	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
431946003901	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
431946003902	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
431946003903	putative catalytic cysteine [active]
431946003904	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
431946003905	putative active site [active]
431946003906	metal binding site [ion binding]; metal-binding site
431946003907	hypothetical protein; Provisional; Region: PRK11111
431946003908	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
431946003909	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
431946003910	peptide binding site [polypeptide binding]; other site
431946003911	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
431946003912	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946003913	dimer interface [polypeptide binding]; other site
431946003914	conserved gate region; other site
431946003915	putative PBP binding loops; other site
431946003916	ABC-ATPase subunit interface; other site
431946003917	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
431946003918	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
431946003919	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946003920	dimer interface [polypeptide binding]; other site
431946003921	conserved gate region; other site
431946003922	putative PBP binding loops; other site
431946003923	ABC-ATPase subunit interface; other site
431946003924	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
431946003925	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
431946003926	Walker A/P-loop; other site
431946003927	ATP binding site [chemical binding]; other site
431946003928	Q-loop/lid; other site
431946003929	ABC transporter signature motif; other site
431946003930	Walker B; other site
431946003931	D-loop; other site
431946003932	H-loop/switch region; other site
431946003933	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
431946003934	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
431946003935	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
431946003936	Walker A/P-loop; other site
431946003937	ATP binding site [chemical binding]; other site
431946003938	Q-loop/lid; other site
431946003939	ABC transporter signature motif; other site
431946003940	Walker B; other site
431946003941	D-loop; other site
431946003942	H-loop/switch region; other site
431946003943	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
431946003944	dsDNA-mimic protein; Reviewed; Region: PRK05094
431946003945	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
431946003946	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
431946003947	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
431946003948	putative active site [active]
431946003949	catalytic site [active]
431946003950	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
431946003951	putative active site [active]
431946003952	catalytic site [active]
431946003953	voltage-gated potassium channel; Provisional; Region: PRK10537
431946003954	Ion channel; Region: Ion_trans_2; pfam07885
431946003955	TrkA-N domain; Region: TrkA_N; pfam02254
431946003956	YciI-like protein; Reviewed; Region: PRK11370
431946003957	transport protein TonB; Provisional; Region: PRK10819
431946003958	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
431946003959	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
431946003960	intracellular septation protein A; Reviewed; Region: PRK00259
431946003961	hypothetical protein; Provisional; Region: PRK02868
431946003962	outer membrane protein W; Provisional; Region: PRK10959
431946003963	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
431946003964	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
431946003965	substrate binding site [chemical binding]; other site
431946003966	active site
431946003967	catalytic residues [active]
431946003968	heterodimer interface [polypeptide binding]; other site
431946003969	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
431946003970	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
431946003971	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946003972	catalytic residue [active]
431946003973	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
431946003974	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
431946003975	active site
431946003976	ribulose/triose binding site [chemical binding]; other site
431946003977	phosphate binding site [ion binding]; other site
431946003978	substrate (anthranilate) binding pocket [chemical binding]; other site
431946003979	product (indole) binding pocket [chemical binding]; other site
431946003980	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
431946003981	active site
431946003982	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK09522
431946003983	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
431946003984	glutamine binding [chemical binding]; other site
431946003985	catalytic triad [active]
431946003986	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
431946003987	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
431946003988	anthranilate synthase component I; Provisional; Region: PRK13564
431946003989	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
431946003990	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
431946003991	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
431946003992	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
431946003993	active site
431946003994	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
431946003995	hypothetical protein; Provisional; Region: PRK11630
431946003996	Predicted membrane protein (DUF2207); Region: DUF2207; pfam09972
431946003997	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
431946003998	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
431946003999	RNA binding surface [nucleotide binding]; other site
431946004000	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
431946004001	probable active site [active]
431946004002	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
431946004003	Cob(I)alamin adenosyltransferase N terminal; Region: Co_AT_N; pfam12557
431946004004	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
431946004005	homodimer interface [polypeptide binding]; other site
431946004006	Walker A motif; other site
431946004007	ATP binding site [chemical binding]; other site
431946004008	hydroxycobalamin binding site [chemical binding]; other site
431946004009	Walker B motif; other site
431946004010	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
431946004011	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
431946004012	NADP binding site [chemical binding]; other site
431946004013	homodimer interface [polypeptide binding]; other site
431946004014	active site
431946004015	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
431946004016	putative inner membrane peptidase; Provisional; Region: PRK11778
431946004017	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
431946004018	tandem repeat interface [polypeptide binding]; other site
431946004019	oligomer interface [polypeptide binding]; other site
431946004020	active site residues [active]
431946004021	hypothetical protein; Provisional; Region: PRK11037
431946004022	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
431946004023	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
431946004024	active site
431946004025	interdomain interaction site; other site
431946004026	putative metal-binding site [ion binding]; other site
431946004027	nucleotide binding site [chemical binding]; other site
431946004028	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
431946004029	domain I; other site
431946004030	DNA binding groove [nucleotide binding]
431946004031	phosphate binding site [ion binding]; other site
431946004032	domain II; other site
431946004033	domain III; other site
431946004034	nucleotide binding site [chemical binding]; other site
431946004035	catalytic site [active]
431946004036	domain IV; other site
431946004037	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
431946004038	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
431946004039	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
431946004040	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
431946004041	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
431946004042	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946004043	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
431946004044	substrate binding site [chemical binding]; other site
431946004045	putative dimerization interface [polypeptide binding]; other site
431946004046	aconitate hydratase; Validated; Region: PRK09277
431946004047	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
431946004048	substrate binding site [chemical binding]; other site
431946004049	ligand binding site [chemical binding]; other site
431946004050	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
431946004051	substrate binding site [chemical binding]; other site
431946004052	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
431946004053	dimerization interface [polypeptide binding]; other site
431946004054	active site
431946004055	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
431946004056	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
431946004057	active site
431946004058	Predicted membrane protein [Function unknown]; Region: COG3771
431946004059	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
431946004060	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
431946004061	TPR motif; other site
431946004062	binding surface
431946004063	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
431946004064	binding surface
431946004065	TPR motif; other site
431946004066	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
431946004067	active site
431946004068	dimer interface [polypeptide binding]; other site
431946004069	translation initiation factor Sui1; Validated; Region: PRK06824
431946004070	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
431946004071	putative rRNA binding site [nucleotide binding]; other site
431946004072	lipoprotein; Provisional; Region: PRK10540
431946004073	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
431946004074	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
431946004075	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
431946004076	hypothetical protein; Provisional; Region: PRK13658
431946004077	RNase II stability modulator; Provisional; Region: PRK10060
431946004078	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
431946004079	putative active site [active]
431946004080	heme pocket [chemical binding]; other site
431946004081	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
431946004082	metal binding site [ion binding]; metal-binding site
431946004083	active site
431946004084	I-site; other site
431946004085	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
431946004086	exoribonuclease II; Provisional; Region: PRK05054
431946004087	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
431946004088	RNB domain; Region: RNB; pfam00773
431946004089	S1 RNA binding domain; Region: S1; pfam00575
431946004090	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950
431946004091	Uncharacterized conserved protein [Function unknown]; Region: COG2128
431946004092	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
431946004093	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
431946004094	NAD binding site [chemical binding]; other site
431946004095	homotetramer interface [polypeptide binding]; other site
431946004096	homodimer interface [polypeptide binding]; other site
431946004097	substrate binding site [chemical binding]; other site
431946004098	active site
431946004099	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
431946004100	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
431946004101	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
431946004102	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
431946004103	HlyD family secretion protein; Region: HlyD_3; pfam13437
431946004104	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
431946004105	Protein export membrane protein; Region: SecD_SecF; cl14618
431946004106	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
431946004107	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
431946004108	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946004109	putative substrate translocation pore; other site
431946004110	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
431946004111	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
431946004112	Walker A/P-loop; other site
431946004113	ATP binding site [chemical binding]; other site
431946004114	Q-loop/lid; other site
431946004115	ABC transporter signature motif; other site
431946004116	Walker B; other site
431946004117	D-loop; other site
431946004118	H-loop/switch region; other site
431946004119	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
431946004120	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
431946004121	Walker A/P-loop; other site
431946004122	ATP binding site [chemical binding]; other site
431946004123	Q-loop/lid; other site
431946004124	ABC transporter signature motif; other site
431946004125	Walker B; other site
431946004126	D-loop; other site
431946004127	H-loop/switch region; other site
431946004128	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
431946004129	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
431946004130	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
431946004131	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946004132	dimer interface [polypeptide binding]; other site
431946004133	conserved gate region; other site
431946004134	putative PBP binding loops; other site
431946004135	ABC-ATPase subunit interface; other site
431946004136	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
431946004137	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946004138	dimer interface [polypeptide binding]; other site
431946004139	conserved gate region; other site
431946004140	putative PBP binding loops; other site
431946004141	ABC-ATPase subunit interface; other site
431946004142	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
431946004143	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
431946004144	peptide binding site [polypeptide binding]; other site
431946004145	Protein of unknown function (DUF2543); Region: DUF2543; pfam10820
431946004146	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
431946004147	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946004148	Walker A motif; other site
431946004149	ATP binding site [chemical binding]; other site
431946004150	Walker B motif; other site
431946004151	arginine finger; other site
431946004152	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
431946004153	phage shock protein PspA; Provisional; Region: PRK10698
431946004154	phage shock protein B; Provisional; Region: pspB; PRK09458
431946004155	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
431946004156	phage shock protein C; Region: phageshock_pspC; TIGR02978
431946004157	peripheral inner membrane phage-shock protein; Provisional; Region: PRK10497
431946004158	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
431946004159	active site residue [active]
431946004160	Alpha amylase catalytic domain found in sucrose phosphorylase-like proteins (also called sucrose glucosyltransferase, disaccharide glucosyltransferase, and sucrose-phosphate alpha-D glucosyltransferase); Region: AmyAc_Sucrose_phosphorylase-like_1; cd11356
431946004161	sucrose phosphorylase; Provisional; Region: PRK13840
431946004162	active site
431946004163	homodimer interface [polypeptide binding]; other site
431946004164	catalytic site [active]
431946004165	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
431946004166	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
431946004167	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
431946004168	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946004169	dimer interface [polypeptide binding]; other site
431946004170	conserved gate region; other site
431946004171	putative PBP binding loops; other site
431946004172	ABC-ATPase subunit interface; other site
431946004173	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
431946004174	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946004175	dimer interface [polypeptide binding]; other site
431946004176	conserved gate region; other site
431946004177	putative PBP binding loops; other site
431946004178	ABC-ATPase subunit interface; other site
431946004179	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
431946004180	2-desacetyl-2-hydroxyethyl bacteriochlorophyllide and other MDR family members; Region: 2-desacetyl-2-hydroxyethyl_bacteriochlorophyllide_; cd08255
431946004181	putative NAD(P) binding site [chemical binding]; other site
431946004182	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
431946004183	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
431946004184	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
431946004185	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
431946004186	Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]; Region: ATH1; COG1554
431946004187	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
431946004188	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
431946004189	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
431946004190	beta-phosphoglucomutase; Region: bPGM; TIGR01990
431946004191	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
431946004192	motif II; other site
431946004193	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
431946004194	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
431946004195	Walker A/P-loop; other site
431946004196	ATP binding site [chemical binding]; other site
431946004197	Q-loop/lid; other site
431946004198	ABC transporter signature motif; other site
431946004199	Walker B; other site
431946004200	D-loop; other site
431946004201	H-loop/switch region; other site
431946004202	TOBE domain; Region: TOBE_2; pfam08402
431946004203	Outer membrane protein G (OmpG); Region: Porin_OmpG; pfam09381
431946004204	Transcriptional regulators [Transcription]; Region: PurR; COG1609
431946004205	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
431946004206	DNA binding site [nucleotide binding]
431946004207	domain linker motif; other site
431946004208	Ligand-binding domain of uncharacterized transcription regulator ycjW which is a member of the LacI-GalR family repressors; Region: PBP1_ycjW_transcription_regulator_like; cd06294
431946004209	putative dimerization interface [polypeptide binding]; other site
431946004210	putative ligand binding site [chemical binding]; other site
431946004211	Predicted ATPase [General function prediction only]; Region: COG3106
431946004212	hypothetical protein; Provisional; Region: PRK05415
431946004213	TIGR01620 family protein; Region: hyp_HI0043
431946004214	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
431946004215	N-terminal ACT domain of the TyrR protein; Region: ACT_TyrR; cd04877
431946004216	putative aromatic amino acid binding site; other site
431946004217	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946004218	Walker A motif; other site
431946004219	ATP binding site [chemical binding]; other site
431946004220	Walker B motif; other site
431946004221	arginine finger; other site
431946004222	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
431946004223	dimer interface [polypeptide binding]; other site
431946004224	catalytic triad [active]
431946004225	peroxidatic and resolving cysteines [active]
431946004226	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
431946004227	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
431946004228	active site
431946004229	Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866
431946004230	Peptidase M14-like domain of Escherichia coli Murein Peptide Amidase A and related proteins; Region: M14_MpaA_like; cd06904
431946004231	putative active site [active]
431946004232	Zn binding site [ion binding]; other site
431946004233	atypical (a) SDRs, subgroup 6; Region: SDR_a6; cd05267
431946004234	NADH(P)-binding; Region: NAD_binding_10; pfam13460
431946004235	putative NAD(P) binding site [chemical binding]; other site
431946004236	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
431946004237	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
431946004238	Transcriptional regulator [Transcription]; Region: LysR; COG0583
431946004239	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946004240	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
431946004241	putative effector binding pocket; other site
431946004242	putative dimerization interface [polypeptide binding]; other site
431946004243	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
431946004244	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
431946004245	peptide binding site [polypeptide binding]; other site
431946004246	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
431946004247	Mechanosensitive ion channel; Region: MS_channel; pfam00924
431946004248	Protein of unknown function (DUF2534); Region: DUF2534; pfam10749
431946004249	universal stress protein UspE; Provisional; Region: PRK11175
431946004250	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
431946004251	Ligand Binding Site [chemical binding]; other site
431946004252	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
431946004253	Ligand Binding Site [chemical binding]; other site
431946004254	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
431946004255	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
431946004256	ligand binding site [chemical binding]; other site
431946004257	flexible hinge region; other site
431946004258	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
431946004259	putative switch regulator; other site
431946004260	non-specific DNA interactions [nucleotide binding]; other site
431946004261	DNA binding site [nucleotide binding]
431946004262	sequence specific DNA binding site [nucleotide binding]; other site
431946004263	putative cAMP binding site [chemical binding]; other site
431946004264	O-6-alkylguanine-DNA:cysteine-protein methyltransferase; Provisional; Region: PRK10286
431946004265	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
431946004266	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
431946004267	DNA binding site [nucleotide binding]
431946004268	active site
431946004269	AbgT putative transporter family; Region: ABG_transport; cl17431
431946004270	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
431946004271	Helix-turn-helix domain; Region: HTH_18; pfam12833
431946004272	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
431946004273	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
431946004274	HlyD family secretion protein; Region: HlyD_3; pfam13437
431946004275	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
431946004276	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946004277	putative substrate translocation pore; other site
431946004278	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946004279	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
431946004280	Smr domain; Region: Smr; pfam01713
431946004281	PAS domain S-box; Region: sensory_box; TIGR00229
431946004282	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
431946004283	putative active site [active]
431946004284	heme pocket [chemical binding]; other site
431946004285	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
431946004286	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
431946004287	metal binding site [ion binding]; metal-binding site
431946004288	active site
431946004289	I-site; other site
431946004290	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
431946004291	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
431946004292	Cl binding site [ion binding]; other site
431946004293	oligomer interface [polypeptide binding]; other site
431946004294	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
431946004295	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
431946004296	ATP binding site [chemical binding]; other site
431946004297	Mg++ binding site [ion binding]; other site
431946004298	motif III; other site
431946004299	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
431946004300	nucleotide binding region [chemical binding]; other site
431946004301	ATP-binding site [chemical binding]; other site
431946004302	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
431946004303	putative RNA binding site [nucleotide binding]; other site
431946004304	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
431946004305	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
431946004306	Ligand Binding Site [chemical binding]; other site
431946004307	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
431946004308	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
431946004309	DNA binding site [nucleotide binding]
431946004310	active site
431946004311	Int/Topo IB signature motif; other site
431946004312	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
431946004313	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
431946004314	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
431946004315	Ligand Binding Site [chemical binding]; other site
431946004316	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
431946004317	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
431946004318	trimer interface [polypeptide binding]; other site
431946004319	eyelet of channel; other site
431946004320	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
431946004321	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
431946004322	dimer interface [polypeptide binding]; other site
431946004323	PYR/PP interface [polypeptide binding]; other site
431946004324	TPP binding site [chemical binding]; other site
431946004325	substrate binding site [chemical binding]; other site
431946004326	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
431946004327	Domain of unknown function; Region: EKR; smart00890
431946004328	4Fe-4S binding domain; Region: Fer4_6; pfam12837
431946004329	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
431946004330	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
431946004331	TPP-binding site [chemical binding]; other site
431946004332	dimer interface [polypeptide binding]; other site
431946004333	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
431946004334	Domain of unknown function (DUF333); Region: DUF333; pfam03891
431946004335	heat-inducible protein; Provisional; Region: PRK10449
431946004336	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
431946004337	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
431946004338	putative ligand binding site [chemical binding]; other site
431946004339	putative NAD binding site [chemical binding]; other site
431946004340	catalytic site [active]
431946004341	hypothetical protein; Provisional; Region: PRK10695
431946004342	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
431946004343	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3784
431946004344	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
431946004345	putative CoA binding site [chemical binding]; other site
431946004346	Autotransporter beta-domain; Region: Autotransporter; pfam03797
431946004347	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
431946004348	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
431946004349	active site
431946004350	catalytic tetrad [active]
431946004351	azoreductase; Reviewed; Region: PRK00170
431946004352	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
431946004353	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
431946004354	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
431946004355	ATP binding site [chemical binding]; other site
431946004356	putative Mg++ binding site [ion binding]; other site
431946004357	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
431946004358	nucleotide binding region [chemical binding]; other site
431946004359	ATP-binding site [chemical binding]; other site
431946004360	Helicase associated domain (HA2); Region: HA2; pfam04408
431946004361	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
431946004362	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
431946004363	Uncharacterized conserved protein [Function unknown]; Region: COG1434
431946004364	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
431946004365	putative active site [active]
431946004366	Escherichia coli lactaldehyde dehydrogenase AldA-like; Region: ALDH_LactADH-AldA; cd07088
431946004367	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
431946004368	NAD binding site [chemical binding]; other site
431946004369	catalytic residues [active]
431946004370	substrate binding site [chemical binding]; other site
431946004371	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
431946004372	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
431946004373	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
431946004374	cytochrome b561; Provisional; Region: PRK11513
431946004375	hypothetical protein; Provisional; Region: PRK10040
431946004376	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
431946004377	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
431946004378	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946004379	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
431946004380	dimerization interface [polypeptide binding]; other site
431946004381	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
431946004382	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
431946004383	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
431946004384	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
431946004385	hypothetical protein; Provisional; Region: PRK11415
431946004386	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
431946004387	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
431946004388	Coenzyme A binding pocket [chemical binding]; other site
431946004389	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
431946004390	putative trimer interface [polypeptide binding]; other site
431946004391	putative CoA binding site [chemical binding]; other site
431946004392	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cd00208
431946004393	putative trimer interface [polypeptide binding]; other site
431946004394	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
431946004395	putative CoA binding site [chemical binding]; other site
431946004396	putative trimer interface [polypeptide binding]; other site
431946004397	putative CoA binding site [chemical binding]; other site
431946004398	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
431946004399	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
431946004400	gating phenylalanine in ion channel; other site
431946004401	tellurite resistance protein TehB; Provisional; Region: PRK11207
431946004402	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946004403	S-adenosylmethionine binding site [chemical binding]; other site
431946004404	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
431946004405	benzoate transporter; Region: benE; TIGR00843
431946004406	Uncharacterized protein involved in benzoate metabolism [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BenE; COG3135
431946004407	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
431946004408	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
431946004409	non-specific DNA binding site [nucleotide binding]; other site
431946004410	salt bridge; other site
431946004411	sequence-specific DNA binding site [nucleotide binding]; other site
431946004412	Cupin domain; Region: Cupin_2; pfam07883
431946004413	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
431946004414	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
431946004415	Peptidase family U32; Region: Peptidase_U32; pfam01136
431946004416	Collagenase; Region: DUF3656; pfam12392
431946004417	Protein of unknown function (DUF2554); Region: DUF2554; pfam10829
431946004418	Helix-turn-helix; Region: HTH_3; pfam01381
431946004419	sequence-specific DNA binding site [nucleotide binding]; other site
431946004420	salt bridge; other site
431946004421	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
431946004422	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
431946004423	DNA-binding site [nucleotide binding]; DNA binding site
431946004424	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
431946004425	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946004426	homodimer interface [polypeptide binding]; other site
431946004427	catalytic residue [active]
431946004428	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
431946004429	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
431946004430	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
431946004431	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
431946004432	Walker A/P-loop; other site
431946004433	ATP binding site [chemical binding]; other site
431946004434	Q-loop/lid; other site
431946004435	ABC transporter signature motif; other site
431946004436	Walker B; other site
431946004437	D-loop; other site
431946004438	H-loop/switch region; other site
431946004439	TOBE domain; Region: TOBE_2; pfam08402
431946004440	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946004441	dimer interface [polypeptide binding]; other site
431946004442	conserved gate region; other site
431946004443	putative PBP binding loops; other site
431946004444	ABC-ATPase subunit interface; other site
431946004445	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
431946004446	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946004447	ABC-ATPase subunit interface; other site
431946004448	gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK13473
431946004449	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
431946004450	tetrameric interface [polypeptide binding]; other site
431946004451	NAD binding site [chemical binding]; other site
431946004452	catalytic residues [active]
431946004453	substrate binding site [chemical binding]; other site
431946004454	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
431946004455	Protein of unknown function (DUF2526); Region: DUF2526; pfam10735
431946004456	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
431946004457	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
431946004458	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
431946004459	colanic acid/biofilm transcriptional regulator; Provisional; Region: PRK11414
431946004460	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
431946004461	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
431946004462	N-terminal plug; other site
431946004463	ligand-binding site [chemical binding]; other site
431946004464	PQQ-like domain; Region: PQQ_2; pfam13360
431946004465	L-asparagine permease; Provisional; Region: PRK15049
431946004466	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
431946004467	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
431946004468	Transposase [DNA replication, recombination, and repair]; Region: COG5433
431946004469	Transposase [DNA replication, recombination, and repair]; Region: COG5433
431946004470	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
431946004471	N-hydroxyarylamine O-acetyltransferase; Provisional; Region: PRK15047
431946004472	hypothetical protein; Provisional; Region: PRK10281
431946004473	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
431946004474	nitrate reductase 2 subunit delta; Provisional; Region: PRK15054
431946004475	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
431946004476	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
431946004477	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
431946004478	[4Fe-4S] binding site [ion binding]; other site
431946004479	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
431946004480	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
431946004481	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
431946004482	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
431946004483	molybdopterin cofactor binding site; other site
431946004484	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
431946004485	aromatic amino acid exporter; Provisional; Region: PRK11689
431946004486	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
431946004487	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
431946004488	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
431946004489	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
431946004490	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
431946004491	molybdopterin cofactor binding site; other site
431946004492	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
431946004493	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
431946004494	formate dehydrogenase-N subunit gamma; Provisional; Region: PRK10179
431946004495	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
431946004496	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
431946004497	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
431946004498	non-specific DNA binding site [nucleotide binding]; other site
431946004499	salt bridge; other site
431946004500	sequence-specific DNA binding site [nucleotide binding]; other site
431946004501	Plasmid maintenance system killer protein; Region: Plasmid_killer; cl01422
431946004502	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
431946004503	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
431946004504	NAD binding site [chemical binding]; other site
431946004505	substrate binding site [chemical binding]; other site
431946004506	catalytic Zn binding site [ion binding]; other site
431946004507	tetramer interface [polypeptide binding]; other site
431946004508	structural Zn binding site [ion binding]; other site
431946004509	malate dehydrogenase; Provisional; Region: PRK13529
431946004510	Malic enzyme, N-terminal domain; Region: malic; pfam00390
431946004511	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
431946004512	NAD(P) binding site [chemical binding]; other site
431946004513	30S ribosomal subunit S22; Reviewed; Region: rpsV; PRK10057
431946004514	Putative biofilm-dependent modulation protein; Region: BDM; cl11581
431946004515	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
431946004516	cyclic-di-GMP phosphodiesterase; Provisional; Region: PRK11359
431946004517	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
431946004518	putative active site [active]
431946004519	heme pocket [chemical binding]; other site
431946004520	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
431946004521	putative active site [active]
431946004522	heme pocket [chemical binding]; other site
431946004523	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
431946004524	metal binding site [ion binding]; metal-binding site
431946004525	active site
431946004526	I-site; other site
431946004527	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
431946004528	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
431946004529	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1649
431946004530	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
431946004531	glutamate:gamma-aminobutyrate antiporter; Region: 2A0307_GadC; TIGR00910
431946004532	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
431946004533	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946004534	catalytic residue [active]
431946004535	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
431946004536	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
431946004537	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
431946004538	FeS/SAM binding site; other site
431946004539	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
431946004540	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
431946004541	Sulfatase; Region: Sulfatase; pfam00884
431946004542	transcriptional regulator YdeO; Provisional; Region: PRK09940
431946004543	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946004544	putative oxidoreductase; Provisional; Region: PRK09939
431946004545	The MopB_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins; Region: MopB_ydeP; cd02767
431946004546	putative molybdopterin cofactor binding site [chemical binding]; other site
431946004547	The MopB_CT_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. This CD is of the conserved molybdopterin_binding C-terminal (MopB_CT) region...; Region: MopB_CT_ydeP; cd02787
431946004548	putative molybdopterin cofactor binding site; other site
431946004549	Mannose binding  domain of FimH and related proteins; Region: FimH_man-bind; cd10466
431946004550	mannosyl binding site [chemical binding]; other site
431946004551	Fimbrial protein; Region: Fimbrial; pfam00419
431946004552	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
431946004553	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
431946004554	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
431946004555	PapC N-terminal domain; Region: PapC_N; pfam13954
431946004556	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
431946004557	PapC C-terminal domain; Region: PapC_C; pfam13953
431946004558	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
431946004559	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
431946004560	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
431946004561	Fimbrial protein; Region: Fimbrial; cl01416
431946004562	HipA N-terminal domain; Region: Couple_hipA; pfam13657
431946004563	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
431946004564	HipA-like N-terminal domain; Region: HipA_N; pfam07805
431946004565	HipA-like C-terminal domain; Region: HipA_C; pfam07804
431946004566	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
431946004567	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
431946004568	non-specific DNA binding site [nucleotide binding]; other site
431946004569	salt bridge; other site
431946004570	sequence-specific DNA binding site [nucleotide binding]; other site
431946004571	Trans-aconitate methyltransferase [General function prediction only]; Region: Tam; COG4106
431946004572	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946004573	S-adenosylmethionine binding site [chemical binding]; other site
431946004574	Predicted membrane protein [Function unknown]; Region: COG3781
431946004575	altronate oxidoreductase; Provisional; Region: PRK03643
431946004576	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
431946004577	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
431946004578	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
431946004579	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
431946004580	metal binding site [ion binding]; metal-binding site
431946004581	active site
431946004582	I-site; other site
431946004583	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
431946004584	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
431946004585	glutaminase; Provisional; Region: PRK00971
431946004586	putative succinate semialdehyde dehydrogenase; Provisional; Region: PRK13968
431946004587	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
431946004588	NAD(P) binding site [chemical binding]; other site
431946004589	catalytic residues [active]
431946004590	Transcriptional regulator [Transcription]; Region: LysR; COG0583
431946004591	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946004592	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
431946004593	putative dimerization interface [polypeptide binding]; other site
431946004594	putative arabinose transporter; Provisional; Region: PRK03545
431946004595	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946004596	putative substrate translocation pore; other site
431946004597	inner membrane protein; Provisional; Region: PRK10995
431946004598	MarR family; Region: MarR_2; cl17246
431946004599	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
431946004600	DNA-binding transcriptional activator MarA; Provisional; Region: PRK11511
431946004601	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946004602	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946004603	hypothetical protein; Provisional; Region: PRK10106
431946004604	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
431946004605	EamA-like transporter family; Region: EamA; pfam00892
431946004606	EamA-like transporter family; Region: EamA; pfam00892
431946004607	putative transporter; Provisional; Region: PRK10054
431946004608	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946004609	putative substrate translocation pore; other site
431946004610	diguanylate cyclase; Provisional; Region: PRK09894
431946004611	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
431946004612	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
431946004613	metal binding site [ion binding]; metal-binding site
431946004614	active site
431946004615	I-site; other site
431946004616	dipeptidyl carboxypeptidase II; Provisional; Region: PRK10280
431946004617	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
431946004618	active site
431946004619	Zn binding site [ion binding]; other site
431946004620	malonic semialdehyde reductase; Provisional; Region: PRK10538
431946004621	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
431946004622	putative NAD(P) binding site [chemical binding]; other site
431946004623	homodimer interface [polypeptide binding]; other site
431946004624	homotetramer interface [polypeptide binding]; other site
431946004625	active site
431946004626	Transcriptional regulators [Transcription]; Region: GntR; COG1802
431946004627	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
431946004628	DNA-binding site [nucleotide binding]; DNA binding site
431946004629	FCD domain; Region: FCD; pfam07729
431946004630	putative selenium-binding protein YdfZ; Region: YdfZ_fam; TIGR03318
431946004631	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
431946004632	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
431946004633	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
431946004634	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946004635	metabolite-proton symporter; Region: 2A0106; TIGR00883
431946004636	putative substrate translocation pore; other site
431946004637	putative oxidoreductase; Provisional; Region: PRK10083
431946004638	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
431946004639	putative NAD(P) binding site [chemical binding]; other site
431946004640	catalytic Zn binding site [ion binding]; other site
431946004641	structural Zn binding site [ion binding]; other site
431946004642	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
431946004643	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
431946004644	putative active site pocket [active]
431946004645	putative metal binding site [ion binding]; other site
431946004646	hypothetical protein; Provisional; Region: PRK02237
431946004647	hypothetical protein; Provisional; Region: PRK13659
431946004648	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
431946004649	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
431946004650	Coenzyme A binding pocket [chemical binding]; other site
431946004651	Uncharacterized protein family (UPF0257); Region: UPF0257; pfam06788
431946004652	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
431946004653	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
431946004654	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
431946004655	putative [Fe4-S4] binding site [ion binding]; other site
431946004656	putative molybdopterin cofactor binding site [chemical binding]; other site
431946004657	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
431946004658	putative molybdopterin cofactor binding site; other site
431946004659	potential frameshift: common BLAST hit: gi|218689508|ref|YP_002397720.1| oxidoreductase subunit
431946004660	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
431946004661	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
431946004662	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
431946004663	4Fe-4S binding domain; Region: Fer4; cl02805
431946004664	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
431946004665	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
431946004666	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
431946004667	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
431946004668	Cl- selectivity filter; other site
431946004669	Cl- binding residues [ion binding]; other site
431946004670	pore gating glutamate residue; other site
431946004671	dimer interface [polypeptide binding]; other site
431946004672	putative dithiobiotin synthetase; Provisional; Region: PRK12374
431946004673	AAA domain; Region: AAA_26; pfam13500
431946004674	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
431946004675	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
431946004676	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
431946004677	nucleotide binding site [chemical binding]; other site
431946004678	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
431946004679	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946004680	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
431946004681	dimerization interface [polypeptide binding]; other site
431946004682	substrate binding pocket [chemical binding]; other site
431946004683	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
431946004684	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946004685	putative substrate translocation pore; other site
431946004686	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
431946004687	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
431946004688	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
431946004689	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; PRK12287
431946004690	Domain of unknown function DUF20; Region: UPF0118; pfam01594
431946004691	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
431946004692	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
431946004693	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
431946004694	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
431946004695	ligand binding site [chemical binding]; other site
431946004696	homodimer interface [polypeptide binding]; other site
431946004697	NAD(P) binding site [chemical binding]; other site
431946004698	trimer interface B [polypeptide binding]; other site
431946004699	trimer interface A [polypeptide binding]; other site
431946004700	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
431946004701	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
431946004702	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
431946004703	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
431946004704	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
431946004705	Spore germination protein; Region: Spore_permease; cl17796
431946004706	dihydromonapterin reductase; Provisional; Region: PRK06483
431946004707	pteridine reductase (PR), classical (c) SDRs; Region: PR_SDR_c; cd05357
431946004708	NADP binding site [chemical binding]; other site
431946004709	substrate binding pocket [chemical binding]; other site
431946004710	active site
431946004711	GlpM protein; Region: GlpM; pfam06942
431946004712	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
431946004713	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946004714	active site
431946004715	phosphorylation site [posttranslational modification]
431946004716	intermolecular recognition site; other site
431946004717	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
431946004718	DNA binding site [nucleotide binding]
431946004719	sensor protein RstB; Provisional; Region: PRK10604
431946004720	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
431946004721	dimerization interface [polypeptide binding]; other site
431946004722	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
431946004723	dimer interface [polypeptide binding]; other site
431946004724	phosphorylation site [posttranslational modification]
431946004725	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946004726	ATP binding site [chemical binding]; other site
431946004727	Mg2+ binding site [ion binding]; other site
431946004728	G-X-G motif; other site
431946004729	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
431946004730	fumarate hydratase; Reviewed; Region: fumC; PRK00485
431946004731	Class II fumarases; Region: Fumarase_classII; cd01362
431946004732	active site
431946004733	tetramer interface [polypeptide binding]; other site
431946004734	fumarate hydratase; Provisional; Region: PRK15389
431946004735	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
431946004736	Fumarase C-terminus; Region: Fumerase_C; pfam05683
431946004737	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
431946004738	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
431946004739	mannose-6-phosphate isomerase, class I; Region: manA; TIGR00218
431946004740	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
431946004741	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
431946004742	putative outer membrane porin protein; Provisional; Region: PRK11379
431946004743	glucuronide transporter; Provisional; Region: PRK09848
431946004744	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
431946004745	beta-D-glucuronidase; Provisional; Region: PRK10150
431946004746	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
431946004747	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
431946004748	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
431946004749	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
431946004750	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
431946004751	7-alpha-hydroxysteroid dehydrogenase; Validated; Region: PRK06113
431946004752	7 alpha-hydroxysteroid dehydrogenase (7 alpha-HSDH), classical (c) SDRs; Region: 7_alpha_HSDH_SDR_c; cd05365
431946004753	NAD binding site [chemical binding]; other site
431946004754	substrate binding site [chemical binding]; other site
431946004755	homotetramer interface [polypeptide binding]; other site
431946004756	homodimer interface [polypeptide binding]; other site
431946004757	active site
431946004758	DNA-binding transcriptional repressor MalI; Provisional; Region: PRK10014
431946004759	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
431946004760	DNA binding site [nucleotide binding]
431946004761	domain linker motif; other site
431946004762	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
431946004763	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
431946004764	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
431946004765	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
431946004766	active site turn [active]
431946004767	phosphorylation site [posttranslational modification]
431946004768	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
431946004769	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
431946004770	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946004771	homodimer interface [polypeptide binding]; other site
431946004772	catalytic residue [active]
431946004773	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
431946004774	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
431946004775	active site
431946004776	purine riboside binding site [chemical binding]; other site
431946004777	putative oxidoreductase; Provisional; Region: PRK11579
431946004778	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
431946004779	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
431946004780	oriC-binding nucleoid-associated protein; Provisional; Region: PRK10391
431946004781	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
431946004782	electron transport complex protein RsxA; Provisional; Region: PRK05151
431946004783	electron transport complex protein RnfB; Provisional; Region: PRK05113
431946004784	Putative Fe-S cluster; Region: FeS; pfam04060
431946004785	4Fe-4S binding domain; Region: Fer4; pfam00037
431946004786	Predicted NADH:ubiquinone oxidoreductase, subunit RnfC [Energy production and conversion]; Region: RnfC; COG4656
431946004787	SLBB domain; Region: SLBB; pfam10531
431946004788	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
431946004789	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
431946004790	electron transport complex protein RnfG; Validated; Region: PRK01908
431946004791	electron transport complex RsxE subunit; Provisional; Region: PRK12405
431946004792	endonuclease III; Provisional; Region: PRK10702
431946004793	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
431946004794	minor groove reading motif; other site
431946004795	helix-hairpin-helix signature motif; other site
431946004796	substrate binding pocket [chemical binding]; other site
431946004797	active site
431946004798	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
431946004799	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
431946004800	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946004801	putative substrate translocation pore; other site
431946004802	POT family; Region: PTR2; pfam00854
431946004803	glutathionine S-transferase; Provisional; Region: PRK10542
431946004804	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
431946004805	C-terminal domain interface [polypeptide binding]; other site
431946004806	GSH binding site (G-site) [chemical binding]; other site
431946004807	dimer interface [polypeptide binding]; other site
431946004808	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
431946004809	N-terminal domain interface [polypeptide binding]; other site
431946004810	dimer interface [polypeptide binding]; other site
431946004811	substrate binding pocket (H-site) [chemical binding]; other site
431946004812	pyridoxamine kinase; Validated; Region: PRK05756
431946004813	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
431946004814	dimer interface [polypeptide binding]; other site
431946004815	pyridoxal binding site [chemical binding]; other site
431946004816	ATP binding site [chemical binding]; other site
431946004817	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
431946004818	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
431946004819	active site
431946004820	HIGH motif; other site
431946004821	dimer interface [polypeptide binding]; other site
431946004822	KMSKS motif; other site
431946004823	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
431946004824	RNA binding surface [nucleotide binding]; other site
431946004825	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
431946004826	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
431946004827	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
431946004828	lysozyme inhibitor; Provisional; Region: PRK11372
431946004829	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
431946004830	Uncharacterized protein family (UPF0075); Region: UPF0075; pfam03702
431946004831	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
431946004832	transcriptional regulator SlyA; Provisional; Region: PRK03573
431946004833	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
431946004834	Protein of unknown function (DUF1656); Region: DUF1656; cl11658
431946004835	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
431946004836	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
431946004837	HlyD family secretion protein; Region: HlyD_3; pfam13437
431946004838	Fusaric acid resistance protein family; Region: FUSC; pfam04632
431946004839	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
431946004840	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
431946004841	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
431946004842	E-class dimer interface [polypeptide binding]; other site
431946004843	P-class dimer interface [polypeptide binding]; other site
431946004844	active site
431946004845	Cu2+ binding site [ion binding]; other site
431946004846	Zn2+ binding site [ion binding]; other site
431946004847	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
431946004848	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
431946004849	active site
431946004850	catalytic tetrad [active]
431946004851	Predicted Fe-S protein [General function prediction only]; Region: COG3313
431946004852	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
431946004853	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
431946004854	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
431946004855	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
431946004856	FMN binding site [chemical binding]; other site
431946004857	active site
431946004858	substrate binding site [chemical binding]; other site
431946004859	catalytic residue [active]
431946004860	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
431946004861	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
431946004862	dimer interface [polypeptide binding]; other site
431946004863	active site
431946004864	metal binding site [ion binding]; metal-binding site
431946004865	glutathione binding site [chemical binding]; other site
431946004866	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
431946004867	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
431946004868	dimer interface [polypeptide binding]; other site
431946004869	catalytic site [active]
431946004870	putative active site [active]
431946004871	putative substrate binding site [chemical binding]; other site
431946004872	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
431946004873	putative GSH binding site [chemical binding]; other site
431946004874	catalytic residues [active]
431946004875	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
431946004876	NlpC/P60 family; Region: NLPC_P60; pfam00877
431946004877	superoxide dismutase; Provisional; Region: PRK10543
431946004878	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
431946004879	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
431946004880	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946004881	Major Facilitator Superfamily; Region: MFS_1; pfam07690
431946004882	putative substrate translocation pore; other site
431946004883	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
431946004884	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
431946004885	DNA binding site [nucleotide binding]
431946004886	domain linker motif; other site
431946004887	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
431946004888	dimerization interface [polypeptide binding]; other site
431946004889	ligand binding site [chemical binding]; other site
431946004890	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
431946004891	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946004892	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
431946004893	dimerization interface [polypeptide binding]; other site
431946004894	putative transporter; Provisional; Region: PRK11043
431946004895	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946004896	putative substrate translocation pore; other site
431946004897	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
431946004898	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
431946004899	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946004900	S-adenosylmethionine binding site [chemical binding]; other site
431946004901	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
431946004902	Lumazine binding domain; Region: Lum_binding; pfam00677
431946004903	Lumazine binding domain; Region: Lum_binding; pfam00677
431946004904	multidrug efflux protein; Reviewed; Region: PRK01766
431946004905	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
431946004906	cation binding site [ion binding]; other site
431946004907	hypothetical protein; Provisional; Region: PRK09945
431946004908	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
431946004909	putative monooxygenase; Provisional; Region: PRK11118
431946004910	hypothetical protein; Provisional; Region: PRK09897
431946004911	FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454
431946004912	hypothetical protein; Provisional; Region: PRK09946
431946004913	thiosulfate reductase cytochrome B subunit; Provisional; Region: PRK15006
431946004914	Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion]; Region: COG4117
431946004915	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
431946004916	hypothetical protein; Provisional; Region: PRK09947
431946004917	putative oxidoreductase; Provisional; Region: PRK09849
431946004918	Aldehyde ferredoxin oxidoreductase, N-terminal domain; Region: AFOR_N; pfam02730
431946004919	Aldehyde ferredoxin oxidoreductase, domains 2 & 3; Region: AFOR_C; pfam01314
431946004920	hypothetical protein; Provisional; Region: PRK09898
431946004921	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
431946004922	hypothetical protein; Provisional; Region: PRK10292
431946004923	pyruvate kinase; Provisional; Region: PRK09206
431946004924	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
431946004925	domain interfaces; other site
431946004926	active site
431946004927	murein lipoprotein; Provisional; Region: PRK15396
431946004928	L,D-transpeptidase; Provisional; Region: PRK10190
431946004929	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
431946004930	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
431946004931	cysteine desufuration protein SufE; Provisional; Region: PRK09296
431946004932	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
431946004933	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
431946004934	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
431946004935	catalytic residue [active]
431946004936	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
431946004937	FeS assembly protein SufD; Region: sufD; TIGR01981
431946004938	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
431946004939	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
431946004940	Walker A/P-loop; other site
431946004941	ATP binding site [chemical binding]; other site
431946004942	Q-loop/lid; other site
431946004943	ABC transporter signature motif; other site
431946004944	Walker B; other site
431946004945	D-loop; other site
431946004946	H-loop/switch region; other site
431946004947	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
431946004948	putative ABC transporter; Region: ycf24; CHL00085
431946004949	iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504
431946004950	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
431946004951	CoenzymeA binding site [chemical binding]; other site
431946004952	subunit interaction site [polypeptide binding]; other site
431946004953	PHB binding site; other site
431946004954	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
431946004955	FAD binding domain; Region: FAD_binding_4; pfam01565
431946004956	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
431946004957	putative inner membrane protein; Provisional; Region: PRK10983
431946004958	Domain of unknown function DUF20; Region: UPF0118; pfam01594
431946004959	Domain of unknown function (DUF1870); Region: DUF1870; pfam08965
431946004960	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946004961	Major Facilitator Superfamily; Region: MFS_1; pfam07690
431946004962	putative substrate translocation pore; other site
431946004963	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946004964	putative substrate translocation pore; other site
431946004965	quinate/shikimate dehydrogenase; Reviewed; Region: PRK12749
431946004966	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
431946004967	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
431946004968	shikimate binding site; other site
431946004969	NAD(P) binding site [chemical binding]; other site
431946004970	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
431946004971	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
431946004972	active site
431946004973	catalytic residue [active]
431946004974	dimer interface [polypeptide binding]; other site
431946004975	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
431946004976	Coenzyme A transferase; Region: CoA_trans; smart00882
431946004977	Coenzyme A transferase; Region: CoA_trans; cl17247
431946004978	putative acyl-CoA dehydrogenase; Provisional; Region: PRK12341
431946004979	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
431946004980	active site
431946004981	Cupin domain; Region: Cupin_2; pfam07883
431946004982	Winged helix DNA-binding domain (DUF1495); Region: DUF1495; cl01336
431946004983	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
431946004984	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946004985	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
431946004986	Ligand binding site [chemical binding]; other site
431946004987	Electron transfer flavoprotein domain; Region: ETF; pfam01012
431946004988	electron transfer flavoprotein subunit YdiR; Provisional; Region: PRK11916
431946004989	Electron transfer flavoprotein domain; Region: ETF; smart00893
431946004990	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
431946004991	oxidoreductase; Provisional; Region: PRK10015
431946004992	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
431946004993	short chain acyl-CoA synthetase; Reviewed; Region: PRK06087
431946004994	Cyclohexanecarboxylate-CoA ligase (also called cyclohex-1-ene-1-carboxylate:CoA ligase); Region: CHC_CoA_lg; cd05903
431946004995	acyl-activating enzyme (AAE) consensus motif; other site
431946004996	putative AMP binding site [chemical binding]; other site
431946004997	putative active site [active]
431946004998	putative CoA binding site [chemical binding]; other site
431946004999	phosphoenolpyruvate synthase; Validated; Region: PRK06464
431946005000	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
431946005001	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
431946005002	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
431946005003	PEP synthetase regulatory protein; Provisional; Region: PRK05339
431946005004	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
431946005005	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
431946005006	Hemin uptake protein [Inorganic ion transport and metabolism]; Region: HemP; COG4256
431946005007	Uncharacterized conserved protein [Function unknown]; Region: COG0397
431946005008	hypothetical protein; Validated; Region: PRK00029
431946005009	c-di-GMP phosphodiesterase class I (EAL domain) [Signal    transduction mechanisms]; Region: Rtn; COG2200
431946005010	NlpC/P60 family; Region: NLPC_P60; pfam00877
431946005011	vitamin B12-transporter ATPase; Provisional; Region: PRK03695
431946005012	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
431946005013	Walker A/P-loop; other site
431946005014	ATP binding site [chemical binding]; other site
431946005015	Q-loop/lid; other site
431946005016	ABC transporter signature motif; other site
431946005017	Walker B; other site
431946005018	D-loop; other site
431946005019	H-loop/switch region; other site
431946005020	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
431946005021	catalytic residues [active]
431946005022	dimer interface [polypeptide binding]; other site
431946005023	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
431946005024	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
431946005025	ABC-ATPase subunit  interface; other site
431946005026	dimer interface [polypeptide binding]; other site
431946005027	putative PBP binding regions; other site
431946005028	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
431946005029	IHF dimer interface [polypeptide binding]; other site
431946005030	IHF - DNA interface [nucleotide binding]; other site
431946005031	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
431946005032	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
431946005033	putative tRNA-binding site [nucleotide binding]; other site
431946005034	B3/4 domain; Region: B3_4; pfam03483
431946005035	tRNA synthetase B5 domain; Region: B5; smart00874
431946005036	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
431946005037	dimer interface [polypeptide binding]; other site
431946005038	motif 1; other site
431946005039	motif 3; other site
431946005040	motif 2; other site
431946005041	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
431946005042	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
431946005043	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
431946005044	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
431946005045	dimer interface [polypeptide binding]; other site
431946005046	motif 1; other site
431946005047	active site
431946005048	motif 2; other site
431946005049	motif 3; other site
431946005050	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
431946005051	23S rRNA binding site [nucleotide binding]; other site
431946005052	L21 binding site [polypeptide binding]; other site
431946005053	L13 binding site [polypeptide binding]; other site
431946005054	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
431946005055	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
431946005056	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
431946005057	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
431946005058	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
431946005059	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
431946005060	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
431946005061	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
431946005062	active site
431946005063	dimer interface [polypeptide binding]; other site
431946005064	motif 1; other site
431946005065	motif 2; other site
431946005066	motif 3; other site
431946005067	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
431946005068	anticodon binding site; other site
431946005069	potential frameshift: common BLAST hit: gi|218699713|ref|YP_002407342.1| putative ankyrin repeat regulatory protein
431946005070	ShET2 enterotoxin, N-terminal region; Region: Toxin_15; pfam07906
431946005071	ShET2 enterotoxin, N-terminal region; Region: Toxin_15; pfam07906
431946005072	Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG3137
431946005073	6-phosphofructokinase 2; Provisional; Region: PRK10294
431946005074	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
431946005075	putative substrate binding site [chemical binding]; other site
431946005076	putative ATP binding site [chemical binding]; other site
431946005077	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
431946005078	Phosphotransferase enzyme family; Region: APH; pfam01636
431946005079	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
431946005080	active site
431946005081	ATP binding site [chemical binding]; other site
431946005082	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
431946005083	YniB-like protein; Region: YniB; pfam14002
431946005084	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
431946005085	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
431946005086	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
431946005087	motif II; other site
431946005088	inner membrane protein; Provisional; Region: PRK11648
431946005089	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
431946005090	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
431946005091	cell division modulator; Provisional; Region: PRK10113
431946005092	hydroperoxidase II; Provisional; Region: katE; PRK11249
431946005093	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
431946005094	tetramer interface [polypeptide binding]; other site
431946005095	heme binding pocket [chemical binding]; other site
431946005096	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
431946005097	domain interactions; other site
431946005098	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
431946005099	putative active site [active]
431946005100	YdjC motif; other site
431946005101	Mg binding site [ion binding]; other site
431946005102	putative homodimer interface [polypeptide binding]; other site
431946005103	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
431946005104	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
431946005105	NAD binding site [chemical binding]; other site
431946005106	sugar binding site [chemical binding]; other site
431946005107	divalent metal binding site [ion binding]; other site
431946005108	tetramer (dimer of dimers) interface [polypeptide binding]; other site
431946005109	dimer interface [polypeptide binding]; other site
431946005110	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
431946005111	Cupin domain; Region: Cupin_2; pfam07883
431946005112	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946005113	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
431946005114	methionine cluster; other site
431946005115	active site
431946005116	phosphorylation site [posttranslational modification]
431946005117	metal binding site [ion binding]; metal-binding site
431946005118	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
431946005119	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
431946005120	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
431946005121	active site
431946005122	P-loop; other site
431946005123	phosphorylation site [posttranslational modification]
431946005124	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
431946005125	NAD+ synthetase; Region: nadE; TIGR00552
431946005126	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
431946005127	homodimer interface [polypeptide binding]; other site
431946005128	NAD binding pocket [chemical binding]; other site
431946005129	ATP binding pocket [chemical binding]; other site
431946005130	Mg binding site [ion binding]; other site
431946005131	active-site loop [active]
431946005132	nucleotide excision repair endonuclease; Provisional; Region: PRK10545
431946005133	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
431946005134	GIY-YIG motif/motif A; other site
431946005135	active site
431946005136	catalytic site [active]
431946005137	putative DNA binding site [nucleotide binding]; other site
431946005138	metal binding site [ion binding]; metal-binding site
431946005139	hypothetical protein; Provisional; Region: PRK11396
431946005140	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
431946005141	dimer interface [polypeptide binding]; other site
431946005142	Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855
431946005143	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
431946005144	putative active site [active]
431946005145	Zn binding site [ion binding]; other site
431946005146	succinylarginine dihydrolase; Provisional; Region: PRK13281
431946005147	succinylglutamic semialdehyde dehydrogenase; Reviewed; Region: astD; PRK09457
431946005148	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
431946005149	NAD(P) binding site [chemical binding]; other site
431946005150	catalytic residues [active]
431946005151	arginine succinyltransferase; Provisional; Region: PRK10456
431946005152	Arginine/ornithine N-succinyltransferase beta subunit [Amino acid transport and metabolism]; Region: AstA; COG3138
431946005153	bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381
431946005154	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
431946005155	inhibitor-cofactor binding pocket; inhibition site
431946005156	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946005157	catalytic residue [active]
431946005158	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
431946005159	putative catalytic site [active]
431946005160	putative phosphate binding site [ion binding]; other site
431946005161	active site
431946005162	metal binding site A [ion binding]; metal-binding site
431946005163	DNA binding site [nucleotide binding]
431946005164	putative AP binding site [nucleotide binding]; other site
431946005165	putative metal binding site B [ion binding]; other site
431946005166	Uncharacterized conserved protein [Function unknown]; Region: COG0398
431946005167	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
431946005168	Uncharacterized conserved protein [Function unknown]; Region: COG0398
431946005169	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
431946005170	Uncharacterized conserved protein [Function unknown]; Region: COG2128
431946005171	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
431946005172	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4134
431946005173	hypothetical protein; Provisional; Region: PRK11622
431946005174	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4135
431946005175	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946005176	dimer interface [polypeptide binding]; other site
431946005177	conserved gate region; other site
431946005178	putative PBP binding loops; other site
431946005179	ABC-ATPase subunit interface; other site
431946005180	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4136
431946005181	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
431946005182	Walker A/P-loop; other site
431946005183	ATP binding site [chemical binding]; other site
431946005184	Q-loop/lid; other site
431946005185	ABC transporter signature motif; other site
431946005186	Walker B; other site
431946005187	D-loop; other site
431946005188	H-loop/switch region; other site
431946005189	Rhodanese Homology Domain; Region: RHOD; smart00450
431946005190	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
431946005191	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
431946005192	active site residue [active]
431946005193	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
431946005194	active site residue [active]
431946005195	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
431946005196	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
431946005197	active site
431946005198	8-oxo-dGMP binding site [chemical binding]; other site
431946005199	nudix motif; other site
431946005200	metal binding site [ion binding]; metal-binding site
431946005201	Protein of unknown function (DUF1496); Region: DUF1496; pfam07383
431946005202	glutamate dehydrogenase; Provisional; Region: PRK09414
431946005203	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
431946005204	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
431946005205	NAD(P) binding site [chemical binding]; other site
431946005206	DNA topoisomerase III; Provisional; Region: PRK07726
431946005207	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
431946005208	active site
431946005209	putative interdomain interaction site [polypeptide binding]; other site
431946005210	putative metal-binding site [ion binding]; other site
431946005211	putative nucleotide binding site [chemical binding]; other site
431946005212	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
431946005213	domain I; other site
431946005214	DNA binding groove [nucleotide binding]
431946005215	phosphate binding site [ion binding]; other site
431946005216	domain II; other site
431946005217	domain III; other site
431946005218	nucleotide binding site [chemical binding]; other site
431946005219	catalytic site [active]
431946005220	domain IV; other site
431946005221	selenophosphate synthetase; Provisional; Region: PRK00943
431946005222	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
431946005223	dimerization interface [polypeptide binding]; other site
431946005224	putative ATP binding site [chemical binding]; other site
431946005225	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
431946005226	putative FMN binding site [chemical binding]; other site
431946005227	protease 4; Provisional; Region: PRK10949
431946005228	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
431946005229	tandem repeat interface [polypeptide binding]; other site
431946005230	oligomer interface [polypeptide binding]; other site
431946005231	active site residues [active]
431946005232	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019
431946005233	tandem repeat interface [polypeptide binding]; other site
431946005234	oligomer interface [polypeptide binding]; other site
431946005235	active site residues [active]
431946005236	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2859
431946005237	Uncharacterized conserved protein [Function unknown]; Region: COG2968
431946005238	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
431946005239	active site
431946005240	homodimer interface [polypeptide binding]; other site
431946005241	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
431946005242	Isochorismatase family; Region: Isochorismatase; pfam00857
431946005243	catalytic triad [active]
431946005244	metal binding site [ion binding]; metal-binding site
431946005245	conserved cis-peptide bond; other site
431946005246	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
431946005247	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946005248	putative substrate translocation pore; other site
431946005249	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946005250	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
431946005251	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
431946005252	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
431946005253	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
431946005254	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
431946005255	active site
431946005256	catalytic tetrad [active]
431946005257	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
431946005258	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
431946005259	substrate binding site [chemical binding]; other site
431946005260	ATP binding site [chemical binding]; other site
431946005261	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
431946005262	intersubunit interface [polypeptide binding]; other site
431946005263	active site
431946005264	zinc binding site [ion binding]; other site
431946005265	Na+ binding site [ion binding]; other site
431946005266	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
431946005267	Sorbitol dehydrogenase; Region: sorbitol_DH; cd05285
431946005268	inhibitor binding site; inhibition site
431946005269	catalytic Zn binding site [ion binding]; other site
431946005270	structural Zn binding site [ion binding]; other site
431946005271	NADP binding site [chemical binding]; other site
431946005272	tetramer interface [polypeptide binding]; other site
431946005273	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946005274	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946005275	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
431946005276	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH4; cd08258
431946005277	putative NAD(P) binding site [chemical binding]; other site
431946005278	catalytic Zn binding site [ion binding]; other site
431946005279	structural Zn binding site [ion binding]; other site
431946005280	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3139
431946005281	methionine sulfoxide reductase B; Provisional; Region: PRK00222
431946005282	SelR domain; Region: SelR; pfam01641
431946005283	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
431946005284	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
431946005285	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
431946005286	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
431946005287	active site
431946005288	phosphate binding residues; other site
431946005289	catalytic residues [active]
431946005290	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
431946005291	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
431946005292	active site
431946005293	catalytic tetrad [active]
431946005294	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
431946005295	PrkA family serine protein kinase; Provisional; Region: PRK15455
431946005296	AAA ATPase domain; Region: AAA_16; pfam13191
431946005297	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
431946005298	hypothetical protein; Provisional; Region: PRK05325
431946005299	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
431946005300	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
431946005301	metal binding site [ion binding]; metal-binding site
431946005302	active site
431946005303	I-site; other site
431946005304	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
431946005305	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
431946005306	metal binding site [ion binding]; metal-binding site
431946005307	active site
431946005308	I-site; other site
431946005309	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
431946005310	putative deacylase active site [active]
431946005311	Predicted membrane protein [Function unknown]; Region: COG2707
431946005312	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
431946005313	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946005314	cyanate transporter; Region: CynX; TIGR00896
431946005315	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946005316	Uncharacterized conserved protein [Function unknown]; Region: COG3189
431946005317	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
431946005318	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
431946005319	Domain of unknown function (DUF333); Region: DUF333; pfam03891
431946005320	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
431946005321	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
431946005322	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
431946005323	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
431946005324	metal binding site [ion binding]; metal-binding site
431946005325	active site
431946005326	I-site; other site
431946005327	hypothetical protein; Provisional; Region: PRK10457
431946005328	Domain of unknown function (DUF1869); Region: DUF1869; pfam08956
431946005329	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
431946005330	leucine export protein LeuE; Provisional; Region: PRK10958
431946005331	ribonuclease D; Provisional; Region: PRK10829
431946005332	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
431946005333	catalytic site [active]
431946005334	putative active site [active]
431946005335	putative substrate binding site [chemical binding]; other site
431946005336	Helicase and RNase D C-terminal; Region: HRDC; smart00341
431946005337	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
431946005338	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
431946005339	acyl-activating enzyme (AAE) consensus motif; other site
431946005340	putative AMP binding site [chemical binding]; other site
431946005341	putative active site [active]
431946005342	putative CoA binding site [chemical binding]; other site
431946005343	outer membrane lipoprotein, Slp family; Region: slp; TIGR00752
431946005344	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
431946005345	Glycoprotease family; Region: Peptidase_M22; pfam00814
431946005346	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
431946005347	DEAD/DEAH box helicase; Region: DEAD; pfam00270
431946005348	DEAD_2; Region: DEAD_2; pfam06733
431946005349	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
431946005350	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
431946005351	homotrimer interaction site [polypeptide binding]; other site
431946005352	putative active site [active]
431946005353	Domain of unknown function (DUF1889); Region: DUF1889; pfam08986
431946005354	hypothetical protein; Provisional; Region: PRK05114
431946005355	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
431946005356	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
431946005357	aminodeoxychorismate synthase, component I, bacterial clade; Region: pabB; TIGR00553
431946005358	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
431946005359	putative active site [active]
431946005360	putative CoA binding site [chemical binding]; other site
431946005361	nudix motif; other site
431946005362	metal binding site [ion binding]; metal-binding site
431946005363	L-serine deaminase; Provisional; Region: PRK15023
431946005364	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
431946005365	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
431946005366	phage resistance protein; Provisional; Region: PRK10551
431946005367	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
431946005368	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
431946005369	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
431946005370	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
431946005371	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
431946005372	Transporter associated domain; Region: CorC_HlyC; smart01091
431946005373	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
431946005374	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
431946005375	active pocket/dimerization site; other site
431946005376	active site
431946005377	phosphorylation site [posttranslational modification]
431946005378	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
431946005379	active site
431946005380	phosphorylation site [posttranslational modification]
431946005381	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
431946005382	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
431946005383	Predicted membrane protein [Function unknown]; Region: COG4811
431946005384	hypothetical protein; Provisional; Region: PRK11469
431946005385	Domain of unknown function DUF; Region: DUF204; pfam02659
431946005386	Domain of unknown function DUF; Region: DUF204; pfam02659
431946005387	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
431946005388	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946005389	S-adenosylmethionine binding site [chemical binding]; other site
431946005390	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
431946005391	DNA-binding site [nucleotide binding]; DNA binding site
431946005392	RNA-binding motif; other site
431946005393	Protein of unknown function (DUF2627); Region: DUF2527; pfam10736
431946005394	YebO-like protein; Region: YebO; pfam13974
431946005395	PhoPQ regulatory protein; Provisional; Region: PRK10299
431946005396	YobH-like protein; Region: YobH; pfam13996
431946005397	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
431946005398	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
431946005399	dimerization interface [polypeptide binding]; other site
431946005400	putative Zn2+ binding site [ion binding]; other site
431946005401	putative DNA binding site [nucleotide binding]; other site
431946005402	Bacterial transcriptional regulator; Region: IclR; pfam01614
431946005403	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946005404	Major Facilitator Superfamily; Region: MFS_1; pfam07690
431946005405	putative substrate translocation pore; other site
431946005406	Predicted integral membrane protein [Function unknown]; Region: COG5521
431946005407	heat shock protein HtpX; Provisional; Region: PRK05457
431946005408	carboxy-terminal protease; Provisional; Region: PRK11186
431946005409	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
431946005410	protein binding site [polypeptide binding]; other site
431946005411	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
431946005412	Catalytic dyad [active]
431946005413	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
431946005414	ProP expression regulator; Provisional; Region: PRK04950
431946005415	ProQ/FINO family; Region: ProQ; pfam04352
431946005416	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
431946005417	GAF domain; Region: GAF_2; pfam13185
431946005418	integral membrane protein, PqiA family; Region: pqiA_fam; TIGR00155
431946005419	Paraquat-inducible protein A; Region: PqiA; pfam04403
431946005420	Paraquat-inducible protein A; Region: PqiA; pfam04403
431946005421	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
431946005422	mce related protein; Region: MCE; pfam02470
431946005423	mce related protein; Region: MCE; pfam02470
431946005424	mce related protein; Region: MCE; pfam02470
431946005425	mce related protein; Region: MCE; pfam02470
431946005426	mce related protein; Region: MCE; pfam02470
431946005427	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
431946005428	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946005429	S-adenosylmethionine binding site [chemical binding]; other site
431946005430	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
431946005431	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
431946005432	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
431946005433	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
431946005434	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
431946005435	active site
431946005436	metal binding site [ion binding]; metal-binding site
431946005437	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
431946005438	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
431946005439	hypothetical protein; Provisional; Region: PRK10301
431946005440	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
431946005441	Predicted amidohydrolase [General function prediction only]; Region: COG0388
431946005442	Carbon-nitrogen hydrolase; Region: CN_hydrolase; pfam00795
431946005443	exodeoxyribonuclease X; Provisional; Region: PRK07983
431946005444	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
431946005445	active site
431946005446	catalytic site [active]
431946005447	substrate binding site [chemical binding]; other site
431946005448	protease 2; Provisional; Region: PRK10115
431946005449	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
431946005450	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2979
431946005451	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
431946005452	putative metal binding site [ion binding]; other site
431946005453	hypothetical protein; Provisional; Region: PRK13680
431946005454	DNA damage-inducible protein YebG; Provisional; Region: PRK10061
431946005455	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
431946005456	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
431946005457	ATP-grasp domain; Region: ATP-grasp; pfam02222
431946005458	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
431946005459	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
431946005460	active site
431946005461	intersubunit interface [polypeptide binding]; other site
431946005462	catalytic residue [active]
431946005463	phosphogluconate dehydratase; Validated; Region: PRK09054
431946005464	6-phosphogluconate dehydratase; Region: edd; TIGR01196
431946005465	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
431946005466	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
431946005467	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
431946005468	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
431946005469	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
431946005470	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
431946005471	putative active site [active]
431946005472	pyruvate kinase; Provisional; Region: PRK05826
431946005473	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
431946005474	domain interfaces; other site
431946005475	active site
431946005476	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
431946005477	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
431946005478	putative acyl-acceptor binding pocket; other site
431946005479	putative peptidase; Provisional; Region: PRK11649
431946005480	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
431946005481	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
431946005482	Peptidase family M23; Region: Peptidase_M23; pfam01551
431946005483	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
431946005484	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
431946005485	metal binding site [ion binding]; metal-binding site
431946005486	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
431946005487	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
431946005488	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
431946005489	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
431946005490	ABC-ATPase subunit  interface; other site
431946005491	dimer interface [polypeptide binding]; other site
431946005492	putative PBP binding regions; other site
431946005493	HTH-like domain; Region: HTH_21; pfam13276
431946005494	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
431946005495	Integrase core domain; Region: rve; pfam00665
431946005496	Integrase core domain; Region: rve_2; pfam13333
431946005497	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
431946005498	Helix-turn-helix domain; Region: HTH_28; pfam13518
431946005499	Helix-turn-helix domain; Region: HTH_28; pfam13518
431946005500	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
431946005501	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946005502	Walker A motif; other site
431946005503	ATP binding site [chemical binding]; other site
431946005504	Walker B motif; other site
431946005505	arginine finger; other site
431946005506	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
431946005507	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
431946005508	RuvA N terminal domain; Region: RuvA_N; pfam01330
431946005509	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
431946005510	hypothetical protein; Provisional; Region: PRK11470
431946005511	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
431946005512	active site
431946005513	putative DNA-binding cleft [nucleotide binding]; other site
431946005514	dimer interface [polypeptide binding]; other site
431946005515	hypothetical protein; Validated; Region: PRK00110
431946005516	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
431946005517	nudix motif; other site
431946005518	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
431946005519	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
431946005520	dimer interface [polypeptide binding]; other site
431946005521	anticodon binding site; other site
431946005522	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
431946005523	homodimer interface [polypeptide binding]; other site
431946005524	motif 1; other site
431946005525	active site
431946005526	motif 2; other site
431946005527	GAD domain; Region: GAD; pfam02938
431946005528	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
431946005529	motif 3; other site
431946005530	Isochorismatase family; Region: Isochorismatase; pfam00857
431946005531	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
431946005532	catalytic triad [active]
431946005533	conserved cis-peptide bond; other site
431946005534	hypothetical protein; Provisional; Region: PRK10302
431946005535	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
431946005536	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946005537	S-adenosylmethionine binding site [chemical binding]; other site
431946005538	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946005539	S-adenosylmethionine binding site [chemical binding]; other site
431946005540	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
431946005541	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
431946005542	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
431946005543	molybdopterin cofactor binding site [chemical binding]; other site
431946005544	substrate binding site [chemical binding]; other site
431946005545	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
431946005546	molybdopterin cofactor binding site; other site
431946005547	trimethylamine-N-oxide reductase c-type cytochrome TorC; Region: torC; TIGR02162
431946005548	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
431946005549	copper homeostasis protein CutC; Provisional; Region: PRK11572
431946005550	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
431946005551	putative metal binding site [ion binding]; other site
431946005552	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
431946005553	arginyl-tRNA synthetase; Region: argS; TIGR00456
431946005554	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
431946005555	active site
431946005556	HIGH motif; other site
431946005557	KMSK motif region; other site
431946005558	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
431946005559	tRNA binding surface [nucleotide binding]; other site
431946005560	anticodon binding site; other site
431946005561	Flagellar protein FlhE; Region: FlhE; pfam06366
431946005562	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
431946005563	FHIPEP family; Region: FHIPEP; pfam00771
431946005564	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
431946005565	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
431946005566	chemotaxis regulator CheZ; Provisional; Region: PRK11166
431946005567	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
431946005568	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946005569	active site
431946005570	phosphorylation site [posttranslational modification]
431946005571	intermolecular recognition site; other site
431946005572	dimerization interface [polypeptide binding]; other site
431946005573	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
431946005574	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946005575	active site
431946005576	phosphorylation site [posttranslational modification]
431946005577	intermolecular recognition site; other site
431946005578	dimerization interface [polypeptide binding]; other site
431946005579	CheB methylesterase; Region: CheB_methylest; pfam01339
431946005580	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
431946005581	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
431946005582	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946005583	S-adenosylmethionine binding site [chemical binding]; other site
431946005584	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
431946005585	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
431946005586	dimer interface [polypeptide binding]; other site
431946005587	ligand binding site [chemical binding]; other site
431946005588	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
431946005589	dimerization interface [polypeptide binding]; other site
431946005590	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
431946005591	dimer interface [polypeptide binding]; other site
431946005592	putative CheW interface [polypeptide binding]; other site
431946005593	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
431946005594	putative CheA interaction surface; other site
431946005595	chemotaxis protein CheA; Provisional; Region: PRK10547
431946005596	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
431946005597	putative binding surface; other site
431946005598	active site
431946005599	CheY binding; Region: CheY-binding; pfam09078
431946005600	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
431946005601	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946005602	ATP binding site [chemical binding]; other site
431946005603	Mg2+ binding site [ion binding]; other site
431946005604	G-X-G motif; other site
431946005605	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
431946005606	flagellar motor protein MotB; Validated; Region: motB; PRK09041
431946005607	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
431946005608	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
431946005609	ligand binding site [chemical binding]; other site
431946005610	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
431946005611	flagellar motor protein MotA; Validated; Region: PRK09110
431946005612	transcriptional activator FlhC; Provisional; Region: PRK12722
431946005613	transcriptional activator FlhD; Provisional; Region: PRK02909
431946005614	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
431946005615	Ligand Binding Site [chemical binding]; other site
431946005616	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
431946005617	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
431946005618	active site
431946005619	homotetramer interface [polypeptide binding]; other site
431946005620	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187
431946005621	Trehalose-6-phosphatase [Carbohydrate transport and metabolism]; Region: OtsB; COG1877
431946005622	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
431946005623	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
431946005624	TM-ABC transporter signature motif; other site
431946005625	L-arabinose transporter ATP-binding protein; Provisional; Region: araG; PRK11288
431946005626	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
431946005627	Walker A/P-loop; other site
431946005628	ATP binding site [chemical binding]; other site
431946005629	Q-loop/lid; other site
431946005630	ABC transporter signature motif; other site
431946005631	Walker B; other site
431946005632	D-loop; other site
431946005633	H-loop/switch region; other site
431946005634	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
431946005635	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
431946005636	Periplasmic L-arabinose-binding protein (ABP), a member of a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein superfamily; Region: PBP1_arabinose_binding; cd01540
431946005637	ligand binding site [chemical binding]; other site
431946005638	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
431946005639	Ferritin-like domain; Region: Ferritin; pfam00210
431946005640	ferroxidase diiron center [ion binding]; other site
431946005641	Protein of unknown function (DUF2766); Region: DUF2766; pfam10964
431946005642	YecR-like lipoprotein; Region: YecR; pfam13992
431946005643	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
431946005644	Ferritin-like domain; Region: Ferritin; pfam00210
431946005645	ferroxidase diiron center [ion binding]; other site
431946005646	probable metal-binding protein; Region: matur_matur; TIGR03853
431946005647	tyrosine transporter TyrP; Provisional; Region: PRK15132
431946005648	aromatic amino acid transport protein; Region: araaP; TIGR00837
431946005649	hypothetical protein; Provisional; Region: PRK10396
431946005650	yecA family protein; Region: ygfB_yecA; TIGR02292
431946005651	SEC-C motif; Region: SEC-C; pfam02810
431946005652	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
431946005653	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
431946005654	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
431946005655	active site
431946005656	catalytic site [active]
431946005657	putative DNA binding site [nucleotide binding]; other site
431946005658	GIY-YIG motif/motif A; other site
431946005659	metal binding site [ion binding]; metal-binding site
431946005660	UvrB/uvrC motif; Region: UVR; pfam02151
431946005661	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
431946005662	Helix-hairpin-helix motif; Region: HHH; pfam00633
431946005663	response regulator; Provisional; Region: PRK09483
431946005664	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946005665	active site
431946005666	phosphorylation site [posttranslational modification]
431946005667	intermolecular recognition site; other site
431946005668	dimerization interface [polypeptide binding]; other site
431946005669	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
431946005670	DNA binding residues [nucleotide binding]
431946005671	dimerization interface [polypeptide binding]; other site
431946005672	hypothetical protein; Provisional; Region: PRK10613
431946005673	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
431946005674	Autoinducer binding domain; Region: Autoind_bind; pfam03472
431946005675	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
431946005676	DNA binding residues [nucleotide binding]
431946005677	dimerization interface [polypeptide binding]; other site
431946005678	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
431946005679	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
431946005680	Walker A/P-loop; other site
431946005681	ATP binding site [chemical binding]; other site
431946005682	Q-loop/lid; other site
431946005683	ABC transporter signature motif; other site
431946005684	Walker B; other site
431946005685	D-loop; other site
431946005686	H-loop/switch region; other site
431946005687	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
431946005688	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946005689	dimer interface [polypeptide binding]; other site
431946005690	conserved gate region; other site
431946005691	putative PBP binding loops; other site
431946005692	ABC-ATPase subunit interface; other site
431946005693	D-cysteine desulfhydrase; Validated; Region: PRK03910
431946005694	Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449
431946005695	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946005696	catalytic residue [active]
431946005697	cystine transporter subunit; Provisional; Region: PRK11260
431946005698	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
431946005699	substrate binding pocket [chemical binding]; other site
431946005700	membrane-bound complex binding site; other site
431946005701	hinge residues; other site
431946005702	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
431946005703	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
431946005704	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
431946005705	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
431946005706	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
431946005707	DNA binding residues [nucleotide binding]
431946005708	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
431946005709	flagellin; Validated; Region: PRK06819
431946005710	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
431946005711	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
431946005712	flagellar capping protein; Reviewed; Region: fliD; PRK08032
431946005713	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
431946005714	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
431946005715	Flagellar protein FliS; Region: FliS; cl00654
431946005716	flagellar biosynthesis protein FliT; Provisional; Region: PRK10548
431946005717	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
431946005718	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
431946005719	active site
431946005720	Na/Ca binding site [ion binding]; other site
431946005721	catalytic site [active]
431946005722	lipoprotein; Provisional; Region: PRK10397
431946005723	putative inner membrane protein; Provisional; Region: PRK11099
431946005724	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
431946005725	CPxP  motif; other site
431946005726	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
431946005727	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
431946005728	Probable transposase; Region: OrfB_IS605; pfam01385
431946005729	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG1943
431946005730	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
431946005731	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
431946005732	substrate binding site [chemical binding]; other site
431946005733	multidrug efflux protein; Reviewed; Region: emrE; PRK09541
431946005734	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
431946005735	flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF); Region: fliF; TIGR00206
431946005736	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
431946005737	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
431946005738	flagellar motor switch protein FliG; Region: fliG; TIGR00207
431946005739	FliG C-terminal domain; Region: FliG_C; pfam01706
431946005740	flagellar assembly protein H; Validated; Region: fliH; PRK05687
431946005741	Essential protein Yae1, N terminal; Region: Yae1_N; pfam09811
431946005742	Flagellar assembly protein FliH; Region: FliH; pfam02108
431946005743	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
431946005744	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
431946005745	Walker A motif/ATP binding site; other site
431946005746	Walker B motif; other site
431946005747	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
431946005748	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
431946005749	Flagellar hook-length control protein [Cell motility and secretion]; Region: FliK; COG3144
431946005750	flagellar hook-length control protein; Provisional; Region: PRK10118
431946005751	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
431946005752	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
431946005753	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
431946005754	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
431946005755	flagellar motor switch protein; Validated; Region: fliN; PRK05698
431946005756	flagellar biosynthesis protein FliO; Provisional; Region: PRK11486
431946005757	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
431946005758	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
431946005759	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
431946005760	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
431946005761	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
431946005762	DNA binding residues [nucleotide binding]
431946005763	dimerization interface [polypeptide binding]; other site
431946005764	hypothetical protein; Provisional; Region: PRK10708
431946005765	Protein of unknown function (DUF2525); Region: DUF2525; pfam10733
431946005766	mannosyl-3-phosphoglycerate phosphatase; Reviewed; Region: PRK03669
431946005767	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
431946005768	active site
431946005769	motif I; other site
431946005770	motif II; other site
431946005771	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
431946005772	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
431946005773	metal binding site [ion binding]; metal-binding site
431946005774	active site
431946005775	I-site; other site
431946005776	Uncharacterized small protein (DUF2158); Region: DUF2158; cl02293
431946005777	hypothetical protein; Provisional; Region: PRK10062
431946005778	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
431946005779	EamA-like transporter family; Region: EamA; pfam00892
431946005780	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
431946005781	additional DNA contacts [nucleotide binding]; other site
431946005782	mismatch recognition site; other site
431946005783	active site
431946005784	zinc binding site [ion binding]; other site
431946005785	DNA intercalation site [nucleotide binding]; other site
431946005786	DNA cytosine methylase; Provisional; Region: PRK10458
431946005787	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
431946005788	cofactor binding site; other site
431946005789	DNA binding site [nucleotide binding]
431946005790	substrate interaction site [chemical binding]; other site
431946005791	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
431946005792	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
431946005793	Zn2+ binding site [ion binding]; other site
431946005794	Mg2+ binding site [ion binding]; other site
431946005795	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
431946005796	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
431946005797	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
431946005798	trimer interface [polypeptide binding]; other site
431946005799	eyelet of channel; other site
431946005800	chaperone protein HchA; Provisional; Region: PRK04155
431946005801	Type 1 glutamine amidotransferase (GATase1)-like domain found in Escherichia coli Hsp31 protein (EcHsp31); Region: GATase1_EcHsp31_like; cd03148
431946005802	dimer interface [polypeptide binding]; other site
431946005803	metal binding site [ion binding]; metal-binding site
431946005804	potential oxyanion hole; other site
431946005805	potential catalytic triad [active]
431946005806	conserved cys residue [active]
431946005807	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
431946005808	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
431946005809	dimer interface [polypeptide binding]; other site
431946005810	phosphorylation site [posttranslational modification]
431946005811	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946005812	ATP binding site [chemical binding]; other site
431946005813	Mg2+ binding site [ion binding]; other site
431946005814	G-X-G motif; other site
431946005815	transcriptional regulatory protein YedW; Provisional; Region: PRK11517
431946005816	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946005817	active site
431946005818	phosphorylation site [posttranslational modification]
431946005819	intermolecular recognition site; other site
431946005820	dimerization interface [polypeptide binding]; other site
431946005821	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
431946005822	DNA binding site [nucleotide binding]
431946005823	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
431946005824	active site
431946005825	homotetramer interface [polypeptide binding]; other site
431946005826	TMAO/DMSO reductase; Reviewed; Region: PRK05363
431946005827	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
431946005828	Moco binding site; other site
431946005829	metal coordination site [ion binding]; other site
431946005830	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
431946005831	zinc/cadmium-binding protein; Provisional; Region: PRK10306
431946005832	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
431946005833	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
431946005834	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
431946005835	active site
431946005836	Int/Topo IB signature motif; other site
431946005837	salicylate synthase Irp9; Reviewed; Region: PRK06772
431946005838	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
431946005839	muropeptide transporter; Validated; Region: ampG; cl17669
431946005840	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
431946005841	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
431946005842	Walker A/P-loop; other site
431946005843	ATP binding site [chemical binding]; other site
431946005844	Q-loop/lid; other site
431946005845	ABC transporter signature motif; other site
431946005846	Walker B; other site
431946005847	D-loop; other site
431946005848	H-loop/switch region; other site
431946005849	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
431946005850	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
431946005851	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
431946005852	Walker A/P-loop; other site
431946005853	ATP binding site [chemical binding]; other site
431946005854	Q-loop/lid; other site
431946005855	ABC transporter signature motif; other site
431946005856	Walker B; other site
431946005857	D-loop; other site
431946005858	H-loop/switch region; other site
431946005859	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
431946005860	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946005861	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
431946005862	Condensation domain; Region: Condensation; pfam00668
431946005863	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
431946005864	Nonribosomal peptide synthase; Region: NRPS; pfam08415
431946005865	The adenylation domain of nonribosomal peptide synthetases (NRPS), including Streptoalloteichus tallysomycin biosynthesis genes; Region: A_NRPS_TlmIV_like; cd12114
431946005866	acyl-activating enzyme (AAE) consensus motif; other site
431946005867	AMP binding site [chemical binding]; other site
431946005868	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946005869	S-adenosylmethionine binding site [chemical binding]; other site
431946005870	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
431946005871	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
431946005872	Condensation domain; Region: Condensation; pfam00668
431946005873	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
431946005874	Nonribosomal peptide synthase; Region: NRPS; pfam08415
431946005875	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
431946005876	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
431946005877	Beta-ketoacyl synthase; Region: PKS_KS; smart00825
431946005878	active site
431946005879	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
431946005880	Acyl transferase domain in polyketide synthase (PKS) enzymes; Region: PKS_AT; smart00827
431946005881	Methyltransferase domain; Region: Methyltransf_12; pfam08242
431946005882	ketoreductase (KR) and fatty acid synthase (FAS), complex (x) SDRs; Region: KR_FAS_SDR_x; cd05274
431946005883	KR domain; Region: KR; pfam08659
431946005884	NADP binding site [chemical binding]; other site
431946005885	active site
431946005886	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
431946005887	Condensation domain; Region: Condensation; pfam00668
431946005888	Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020
431946005889	Nonribosomal peptide synthase; Region: NRPS; pfam08415
431946005890	Methyltransferase domain; Region: Methyltransf_12; pfam08242
431946005891	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
431946005892	Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319
431946005893	Oxidoreductase (NAD-binding), involved in siderophore biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PchG; COG4693
431946005894	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
431946005895	Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208
431946005896	Peptide arylation enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntE; COG1021
431946005897	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
431946005898	acyl-activating enzyme (AAE) consensus motif; other site
431946005899	active site
431946005900	AMP binding site [chemical binding]; other site
431946005901	substrate binding site [chemical binding]; other site
431946005902	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
431946005903	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
431946005904	N-terminal plug; other site
431946005905	ligand-binding site [chemical binding]; other site
431946005906	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
431946005907	potential frameshift: common BLAST hit: gi|117624169|ref|YP_853082.1| autotransporter
431946005908	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
431946005909	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
431946005910	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
431946005911	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
431946005912	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
431946005913	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
431946005914	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
431946005915	shikimate transporter; Provisional; Region: PRK09952
431946005916	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946005917	putative substrate translocation pore; other site
431946005918	AMP nucleosidase; Provisional; Region: PRK08292
431946005919	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
431946005920	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
431946005921	hypothetical protein; Provisional; Region: PRK12378
431946005922	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
431946005923	nitrogen assimilation transcriptional regulator; Provisional; Region: PRK11233
431946005924	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946005925	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
431946005926	putative dimerization interface [polypeptide binding]; other site
431946005927	transcriptional regulator Cbl; Reviewed; Region: cbl; PRK12679
431946005928	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946005929	The C-terminal substrate binding domain of LysR-type transcriptional regulator Cbl, which is required for expression of sulfate starvation-inducible (ssi) genes, contains the type 2 periplasmic binding fold; Region: PBP2_Cbl; cd08444
431946005930	putative substrate binding site [chemical binding]; other site
431946005931	dimerization interface [polypeptide binding]; other site
431946005932	MATE family multidrug exporter; Provisional; Region: PRK10189
431946005933	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
431946005934	L,D-transpeptidase; Provisional; Region: PRK10190
431946005935	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
431946005936	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
431946005937	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
431946005938	putative dimer interface [polypeptide binding]; other site
431946005939	active site pocket [active]
431946005940	putative cataytic base [active]
431946005941	cobalamin 5'-phosphate synthase/cobalamin synthase; Region: cobS; TIGR00317
431946005942	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
431946005943	homotrimer interface [polypeptide binding]; other site
431946005944	Walker A motif; other site
431946005945	GTP binding site [chemical binding]; other site
431946005946	Walker B motif; other site
431946005947	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
431946005948	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
431946005949	N-terminal plug; other site
431946005950	ligand-binding site [chemical binding]; other site
431946005951	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
431946005952	ParB-like nuclease domain; Region: ParBc; cl02129
431946005953	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
431946005954	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
431946005955	Active Sites [active]
431946005956	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
431946005957	Uncharacterized proteins, LmbE homologs [Function unknown]; Region: COG2120
431946005958	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
431946005959	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
431946005960	DXD motif; other site
431946005961	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
431946005962	putative trimer interface [polypeptide binding]; other site
431946005963	putative CoA binding site [chemical binding]; other site
431946005964	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
431946005965	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
431946005966	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
431946005967	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
431946005968	substrate binding site [chemical binding]; other site
431946005969	dimer interface [polypeptide binding]; other site
431946005970	ATP binding site [chemical binding]; other site
431946005971	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
431946005972	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
431946005973	Protein of unknown function, DUF606; Region: DUF606; pfam04657
431946005974	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
431946005975	active site
431946005976	substrate binding pocket [chemical binding]; other site
431946005977	homodimer interaction site [polypeptide binding]; other site
431946005978	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
431946005979	Transposase; Region: DDE_Tnp_ISL3; pfam01610
431946005980	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cl17393
431946005981	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
431946005982	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
431946005983	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
431946005984	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
431946005985	Transposase; Region: HTH_Tnp_1; pfam01527
431946005986	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
431946005987	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
431946005988	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
431946005989	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
431946005990	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
431946005991	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
431946005992	Transposase; Region: DEDD_Tnp_IS110; pfam01548
431946005993	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
431946005994	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
431946005995	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; pfam05930
431946005996	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946005997	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
431946005998	Walker A motif; other site
431946005999	ATP binding site [chemical binding]; other site
431946006000	Walker B motif; other site
431946006001	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
431946006002	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
431946006003	DNA-binding interface [nucleotide binding]; DNA binding site
431946006004	Integrase core domain; Region: rve; pfam00665
431946006005	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
431946006006	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
431946006007	Walker A/P-loop; other site
431946006008	ATP binding site [chemical binding]; other site
431946006009	Q-loop/lid; other site
431946006010	ABC transporter signature motif; other site
431946006011	Walker B; other site
431946006012	D-loop; other site
431946006013	H-loop/switch region; other site
431946006014	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
431946006015	dimer interface [polypeptide binding]; other site
431946006016	putative PBP binding regions; other site
431946006017	ABC-ATPase subunit  interface; other site
431946006018	Periplasmic binding protein TroA_e.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_e; cd01142
431946006019	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
431946006020	putative ligand binding residues [chemical binding]; other site
431946006021	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
431946006022	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
431946006023	N-terminal plug; other site
431946006024	ligand-binding site [chemical binding]; other site
431946006025	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
431946006026	G1 box; other site
431946006027	GTP/Mg2+ binding site [chemical binding]; other site
431946006028	G2 box; other site
431946006029	Switch I region; other site
431946006030	Switch II region; other site
431946006031	hypothetical protein; Provisional; Region: PRK09866
431946006032	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
431946006033	G1 box; other site
431946006034	GTP/Mg2+ binding site [chemical binding]; other site
431946006035	G2 box; other site
431946006036	Switch I region; other site
431946006037	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
431946006038	G3 box; other site
431946006039	Switch II region; other site
431946006040	GTP/Mg2+ binding site [chemical binding]; other site
431946006041	G4 box; other site
431946006042	G5 box; other site
431946006043	YjcZ-like protein; Region: YjcZ; pfam13990
431946006044	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
431946006045	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
431946006046	nucleophile elbow; other site
431946006047	Hypothetical patatin similar to Z1214 protein of Escherichia coli; Region: Pat_hypo_Ecoli_Z1214_like; cd07209
431946006048	Domain of unknown function (DUF932); Region: DUF932; pfam06067
431946006049	Antirestriction protein; Region: Antirestrict; pfam03230
431946006050	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
431946006051	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
431946006052	MPN+ (JAMM) motif; other site
431946006053	Zinc-binding site [ion binding]; other site
431946006054	Protein of unknown function (DUF987); Region: DUF987; pfam06174
431946006055	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
431946006056	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
431946006057	DNA replication protein [DNA replication, recombination, and repair]; Region: DnaC; COG1484
431946006058	IstB-like ATP binding N-terminal; Region: IstB_IS21_ATP; pfam08483
431946006059	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946006060	Walker A motif; other site
431946006061	ATP binding site [chemical binding]; other site
431946006062	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
431946006063	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
431946006064	DNA binding residues [nucleotide binding]
431946006065	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
431946006066	Integrase core domain; Region: rve; pfam00665
431946006067	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
431946006068	Switch II region; other site
431946006069	G4 box; other site
431946006070	G5 box; other site
431946006071	hypothetical protein; Provisional; Region: PRK05423
431946006072	Predicted membrane protein [Function unknown]; Region: COG1289
431946006073	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
431946006074	DNA gyrase inhibitor; Provisional; Region: PRK10016
431946006075	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
431946006076	D-alanyl-D-alanine carboxypeptidase; Provisional; Region: dacD; PRK11397
431946006077	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
431946006078	exonuclease I; Provisional; Region: sbcB; PRK11779
431946006079	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
431946006080	active site
431946006081	catalytic site [active]
431946006082	substrate binding site [chemical binding]; other site
431946006083	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
431946006084	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
431946006085	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946006086	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
431946006087	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
431946006088	dimerization interface [polypeptide binding]; other site
431946006089	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
431946006090	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
431946006091	putative NAD(P) binding site [chemical binding]; other site
431946006092	Plasmid encoded toxin Txe; Region: Plasmid_Txe; pfam06769
431946006093	antitoxin YefM; Provisional; Region: PRK11409
431946006094	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
431946006095	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
431946006096	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
431946006097	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
431946006098	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
431946006099	NAD binding site [chemical binding]; other site
431946006100	dimerization interface [polypeptide binding]; other site
431946006101	product binding site; other site
431946006102	substrate binding site [chemical binding]; other site
431946006103	zinc binding site [ion binding]; other site
431946006104	catalytic residues [active]
431946006105	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
431946006106	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
431946006107	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946006108	homodimer interface [polypeptide binding]; other site
431946006109	catalytic residue [active]
431946006110	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
431946006111	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
431946006112	active site
431946006113	motif I; other site
431946006114	motif II; other site
431946006115	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
431946006116	putative active site pocket [active]
431946006117	4-fold oligomerization interface [polypeptide binding]; other site
431946006118	metal binding residues [ion binding]; metal-binding site
431946006119	3-fold/trimer interface [polypeptide binding]; other site
431946006120	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
431946006121	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
431946006122	putative active site [active]
431946006123	oxyanion strand; other site
431946006124	catalytic triad [active]
431946006125	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
431946006126	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
431946006127	catalytic residues [active]
431946006128	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
431946006129	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
431946006130	substrate binding site [chemical binding]; other site
431946006131	glutamase interaction surface [polypeptide binding]; other site
431946006132	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
431946006133	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
431946006134	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
431946006135	metal binding site [ion binding]; metal-binding site
431946006136	chain length determinant protein WzzB; Provisional; Region: PRK15471
431946006137	Chain length determinant protein; Region: Wzz; pfam02706
431946006138	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
431946006139	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
431946006140	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
431946006141	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
431946006142	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
431946006143	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
431946006144	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
431946006145	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
431946006146	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
431946006147	Probable Catalytic site; other site
431946006148	metal-binding site
431946006149	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
431946006150	Glycosyl transferases group 1; Region: Glycos_transf_1; pfam00534
431946006151	putative lipopolysaccharide biosynthesis O-acetyl transferase WbbJ; Provisional; Region: PRK09677
431946006152	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
431946006153	trimer interface [polypeptide binding]; other site
431946006154	active site
431946006155	substrate binding site [chemical binding]; other site
431946006156	CoA binding site [chemical binding]; other site
431946006157	beta-1,6-galactofuranosyltransferase; Provisional; Region: PRK09814
431946006158	UDP-galactopyranose mutase [Cell envelope biogenesis, outer membrane]; Region: Glf; COG0562
431946006159	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
431946006160	UDP-galactopyranose mutase; Region: GLF; pfam03275
431946006161	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
431946006162	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
431946006163	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: rmlC; TIGR01221
431946006164	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
431946006165	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
431946006166	substrate binding site; other site
431946006167	tetramer interface; other site
431946006168	dTDP-4-dehydrorhamnose reductase; Provisional; Region: PRK09987
431946006169	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
431946006170	NADP binding site [chemical binding]; other site
431946006171	active site
431946006172	putative substrate binding site [chemical binding]; other site
431946006173	dTDP-glucose 4,6 dehydratase; Provisional; Region: PRK10084
431946006174	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
431946006175	NAD binding site [chemical binding]; other site
431946006176	substrate binding site [chemical binding]; other site
431946006177	homodimer interface [polypeptide binding]; other site
431946006178	active site
431946006179	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
431946006180	active site
431946006181	tetramer interface; other site
431946006182	putative colanic acid biosynthesis protein; Provisional; Region: wcaM; PRK10123
431946006183	colanic acid biosynthesis glycosyltransferase WcaL; Region: wcaL; TIGR04005
431946006184	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
431946006185	putative ADP-binding pocket [chemical binding]; other site
431946006186	Polysaccharide pyruvyl transferase family protein [Cell wall/membrane/envelope biogenesis]; Region: WcaK; COG2327
431946006187	colanic acid biosynthesis pyruvyl transferase WcaK; Region: wcaK; TIGR04006
431946006188	colanic acid exporter; Provisional; Region: PRK10459
431946006189	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
431946006190	putative UDP-glucose lipid carrier transferase; Provisional; Region: PRK10124
431946006191	Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane]; Region: WcaJ; COG2148
431946006192	phosphomannomutase CpsG; Provisional; Region: PRK15414
431946006193	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
431946006194	active site
431946006195	substrate binding site [chemical binding]; other site
431946006196	metal binding site [ion binding]; metal-binding site
431946006197	mannose-1-phosphate guanyltransferase; Provisional; Region: cpsB; PRK15460
431946006198	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
431946006199	Substrate binding site; other site
431946006200	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
431946006201	colanic acid biosynthesis glycosyl transferase WcaI; Region: wcaI; TIGR04007
431946006202	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
431946006203	GDP-mannose glycosyl hydrolase (AKA GDP-mannose mannosyl hydrolase (GDPMH)) is a member of the Nudix hydrolase superfamily. This class of enzymes is unique from other members of the superfamily in two aspects. First, it contains a modified Nudix...; Region: GDPMH; cd03430
431946006204	active site
431946006205	GDP-Mannose binding site [chemical binding]; other site
431946006206	dimer interface [polypeptide binding]; other site
431946006207	modified nudix motif
431946006208	metal binding site [ion binding]; metal-binding site
431946006209	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
431946006210	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
431946006211	NADP binding site [chemical binding]; other site
431946006212	active site
431946006213	putative substrate binding site [chemical binding]; other site
431946006214	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
431946006215	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
431946006216	NADP-binding site; other site
431946006217	homotetramer interface [polypeptide binding]; other site
431946006218	substrate binding site [chemical binding]; other site
431946006219	homodimer interface [polypeptide binding]; other site
431946006220	active site
431946006221	colanic acid biosynthesis acetyltransferase WcaF; Region: WcaF; TIGR04008
431946006222	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
431946006223	putative trimer interface [polypeptide binding]; other site
431946006224	putative active site [active]
431946006225	putative substrate binding site [chemical binding]; other site
431946006226	putative CoA binding site [chemical binding]; other site
431946006227	putative glycosyl transferase; Provisional; Region: PRK10063
431946006228	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
431946006229	metal-binding site
431946006230	putative colanic acid polymerase WcaD; Region: WcaD; TIGR04010
431946006231	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
431946006232	colanic acid biosynthesis glycosyl transferase WcaC; Region: WcaC; TIGR04015
431946006233	putative acyl transferase; Provisional; Region: PRK10191
431946006234	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
431946006235	trimer interface [polypeptide binding]; other site
431946006236	active site
431946006237	substrate binding site [chemical binding]; other site
431946006238	CoA binding site [chemical binding]; other site
431946006239	putative glycosyl transferase; Provisional; Region: PRK10018
431946006240	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
431946006241	active site
431946006242	tyrosine kinase; Provisional; Region: PRK11519
431946006243	Chain length determinant protein; Region: Wzz; pfam02706
431946006244	Chain length determinant protein; Region: Wzz; cl15801
431946006245	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
431946006246	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
431946006247	Low molecular weight phosphatase family; Region: LMWPc; cd00115
431946006248	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
431946006249	active site
431946006250	polysaccharide export protein Wza; Provisional; Region: PRK15078
431946006251	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
431946006252	SLBB domain; Region: SLBB; pfam10531
431946006253	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
431946006254	FOG: CBS domain [General function prediction only]; Region: COG0517
431946006255	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
431946006256	Transporter associated domain; Region: CorC_HlyC; smart01091
431946006257	putative assembly protein; Provisional; Region: PRK10833
431946006258	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
431946006259	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
431946006260	trimer interface [polypeptide binding]; other site
431946006261	active site
431946006262	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
431946006263	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
431946006264	ATP-binding site [chemical binding]; other site
431946006265	Sugar specificity; other site
431946006266	Pyrimidine base specificity; other site
431946006267	Predicted integral membrane sensor domain [Signal transduction mechanisms]; Region: COG3447
431946006268	putative diguanylate cyclase; Provisional; Region: PRK09776
431946006269	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
431946006270	putative active site [active]
431946006271	heme pocket [chemical binding]; other site
431946006272	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
431946006273	putative active site [active]
431946006274	heme pocket [chemical binding]; other site
431946006275	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
431946006276	putative active site [active]
431946006277	heme pocket [chemical binding]; other site
431946006278	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
431946006279	metal binding site [ion binding]; metal-binding site
431946006280	active site
431946006281	I-site; other site
431946006282	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290
431946006283	3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308
431946006284	AlkA N-terminal domain; Region: AlkA_N; smart01009
431946006285	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
431946006286	minor groove reading motif; other site
431946006287	helix-hairpin-helix signature motif; other site
431946006288	substrate binding pocket [chemical binding]; other site
431946006289	active site
431946006290	putative chaperone; Provisional; Region: PRK11678
431946006291	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
431946006292	nucleotide binding site [chemical binding]; other site
431946006293	putative NEF/HSP70 interaction site [polypeptide binding]; other site
431946006294	SBD interface [polypeptide binding]; other site
431946006295	Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains [General function prediction only]; Region: COG4248
431946006296	Y-family of DNA polymerases; Region: PolY; cl12025
431946006297	Protein phosphatase 2C; Region: PP2C_2; pfam13672
431946006298	VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subfamily; cd01464
431946006299	metal ion-dependent adhesion site (MIDAS); other site
431946006300	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
431946006301	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
431946006302	HlyD family secretion protein; Region: HlyD_3; pfam13437
431946006303	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
431946006304	Protein export membrane protein; Region: SecD_SecF; cl14618
431946006305	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
431946006306	putative transporter; Provisional; Region: PRK10504
431946006307	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946006308	putative substrate translocation pore; other site
431946006309	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cl17904
431946006310	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
431946006311	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
431946006312	dimerization interface [polypeptide binding]; other site
431946006313	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
431946006314	dimer interface [polypeptide binding]; other site
431946006315	phosphorylation site [posttranslational modification]
431946006316	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946006317	ATP binding site [chemical binding]; other site
431946006318	Mg2+ binding site [ion binding]; other site
431946006319	G-X-G motif; other site
431946006320	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
431946006321	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946006322	active site
431946006323	phosphorylation site [posttranslational modification]
431946006324	intermolecular recognition site; other site
431946006325	dimerization interface [polypeptide binding]; other site
431946006326	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
431946006327	DNA binding site [nucleotide binding]
431946006328	Uncharacterized conserved protein [Function unknown]; Region: COG3422
431946006329	putative protease; Provisional; Region: PRK15452
431946006330	Peptidase family U32; Region: Peptidase_U32; pfam01136
431946006331	lipid kinase; Reviewed; Region: PRK13054
431946006332	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
431946006333	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
431946006334	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
431946006335	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
431946006336	galactitol-1-phosphate dehydrogenase; Provisional; Region: PRK10309
431946006337	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
431946006338	putative NAD(P) binding site [chemical binding]; other site
431946006339	catalytic Zn binding site [ion binding]; other site
431946006340	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
431946006341	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
431946006342	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
431946006343	active site
431946006344	P-loop; other site
431946006345	phosphorylation site [posttranslational modification]
431946006346	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
431946006347	active site
431946006348	phosphorylation site [posttranslational modification]
431946006349	D-tagatose-1,6-bisphosphate aldolase subunit GatZ; Provisional; Region: PRK15052
431946006350	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
431946006351	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
431946006352	intersubunit interface [polypeptide binding]; other site
431946006353	active site
431946006354	zinc binding site [ion binding]; other site
431946006355	Na+ binding site [ion binding]; other site
431946006356	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
431946006357	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
431946006358	putative active site; other site
431946006359	catalytic residue [active]
431946006360	nucleoside transporter; Region: 2A0110; TIGR00889
431946006361	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946006362	putative substrate translocation pore; other site
431946006363	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
431946006364	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
431946006365	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
431946006366	substrate binding site [chemical binding]; other site
431946006367	ATP binding site [chemical binding]; other site
431946006368	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
431946006369	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
431946006370	DNA-binding site [nucleotide binding]; DNA binding site
431946006371	UTRA domain; Region: UTRA; pfam07702
431946006372	Lyzozyme M1 (1,4-beta-N-acetylmuramidase) [Cell envelope biogenesis, outer membrane]; Region: Acm; COG3757
431946006373	YegX is an uncharacterized bacterial protein with a glycosyl hydrolase family 25 (GH25) catalytic domain that is similar in sequence to the CH-type (Chalaropsis-type) lysozymes of the GH25 family of endolysins; Region: GH25_YegX-like; cd06524
431946006374	active site
431946006375	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
431946006376	dimer interface [polypeptide binding]; other site
431946006377	substrate binding site [chemical binding]; other site
431946006378	ATP binding site [chemical binding]; other site
431946006379	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
431946006380	substrate binding site [chemical binding]; other site
431946006381	multimerization interface [polypeptide binding]; other site
431946006382	ATP binding site [chemical binding]; other site
431946006383	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
431946006384	putative metal binding site [ion binding]; other site
431946006385	putative homodimer interface [polypeptide binding]; other site
431946006386	putative homotetramer interface [polypeptide binding]; other site
431946006387	putative homodimer-homodimer interface [polypeptide binding]; other site
431946006388	putative allosteric switch controlling residues; other site
431946006389	nickel/cobalt efflux protein RcnA; Provisional; Region: PRK10019
431946006390	Predicted integral membrane protein [Function unknown]; Region: COG5455
431946006391	putative fimbrial-like adhesin protein StcD; Provisional; Region: PRK15252
431946006392	putative fimbrial biosynthesis regulatory protein; Provisional; Region: PRK15216
431946006393	fimbrial outer membrane usher protein; Provisional; Region: PRK15217
431946006394	PapC N-terminal domain; Region: PapC_N; pfam13954
431946006395	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
431946006396	PapC C-terminal domain; Region: PapC_C; pfam13953
431946006397	putative fimbrial assembly chaperone protein StcB; Provisional; Region: PRK15253
431946006398	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
431946006399	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
431946006400	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
431946006401	Protein of unknown function (DUF2574); Region: DUF2574; pfam10836
431946006402	antiporter inner membrane protein; Provisional; Region: PRK11670
431946006403	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
431946006404	Walker A motif; other site
431946006405	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
431946006406	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
431946006407	active site
431946006408	HIGH motif; other site
431946006409	KMSKS motif; other site
431946006410	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
431946006411	tRNA binding surface [nucleotide binding]; other site
431946006412	anticodon binding site; other site
431946006413	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
431946006414	dimer interface [polypeptide binding]; other site
431946006415	putative tRNA-binding site [nucleotide binding]; other site
431946006416	WGR domain of molybdate metabolism regulator and related proteins; Region: WGR_MMR_like; cd07996
431946006417	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
431946006418	WGR domain of molybdate metabolism regulator and related proteins; Region: WGR_MMR_like; cd07996
431946006419	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
431946006420	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
431946006421	MoxR-like ATPases [General function prediction only]; Region: COG0714
431946006422	AAA domain (dynein-related subfamily); Region: AAA_5; pfam07728
431946006423	Walker A motif; other site
431946006424	ATP binding site [chemical binding]; other site
431946006425	Walker B motif; other site
431946006426	arginine finger; other site
431946006427	VWA domain containing CoxE-like protein; Region: VWA_CoxE; pfam05762
431946006428	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
431946006429	metal ion-dependent adhesion site (MIDAS); other site
431946006430	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
431946006431	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
431946006432	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
431946006433	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
431946006434	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
431946006435	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946006436	active site
431946006437	phosphorylation site [posttranslational modification]
431946006438	intermolecular recognition site; other site
431946006439	dimerization interface [polypeptide binding]; other site
431946006440	LytTr DNA-binding domain; Region: LytTR; pfam04397
431946006441	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
431946006442	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
431946006443	GAF domain; Region: GAF; pfam01590
431946006444	Histidine kinase; Region: His_kinase; pfam06580
431946006445	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946006446	ATP binding site [chemical binding]; other site
431946006447	Mg2+ binding site [ion binding]; other site
431946006448	G-X-G motif; other site
431946006449	transcriptional regulator MirA; Provisional; Region: PRK15043
431946006450	Helix-Turn-Helix DNA binding domain of MlrA-like transcription regulators; Region: HTH_MlrA-like; cd04763
431946006451	DNA binding residues [nucleotide binding]
431946006452	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
431946006453	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946006454	dimer interface [polypeptide binding]; other site
431946006455	conserved gate region; other site
431946006456	putative PBP binding loops; other site
431946006457	ABC-ATPase subunit interface; other site
431946006458	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
431946006459	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
431946006460	Walker A/P-loop; other site
431946006461	ATP binding site [chemical binding]; other site
431946006462	Q-loop/lid; other site
431946006463	ABC transporter signature motif; other site
431946006464	Walker B; other site
431946006465	D-loop; other site
431946006466	H-loop/switch region; other site
431946006467	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
431946006468	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946006469	dimer interface [polypeptide binding]; other site
431946006470	conserved gate region; other site
431946006471	ABC-ATPase subunit interface; other site
431946006472	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
431946006473	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
431946006474	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
431946006475	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
431946006476	D-lactate dehydrogenase; Provisional; Region: PRK11183
431946006477	FAD binding domain; Region: FAD_binding_4; pfam01565
431946006478	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
431946006479	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
431946006480	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
431946006481	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
431946006482	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
431946006483	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
431946006484	oxidoreductase; Provisional; Region: PRK12743
431946006485	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
431946006486	NAD(P) binding site [chemical binding]; other site
431946006487	active site
431946006488	multidrug resistance outer membrane protein MdtQ; Provisional; Region: PRK11459
431946006489	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
431946006490	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
431946006491	FMN binding site [chemical binding]; other site
431946006492	active site
431946006493	catalytic residues [active]
431946006494	substrate binding site [chemical binding]; other site
431946006495	hypothetical protein; Provisional; Region: PRK01821
431946006496	hypothetical protein; Provisional; Region: PRK10711
431946006497	cytidine deaminase; Provisional; Region: PRK09027
431946006498	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
431946006499	active site
431946006500	catalytic motif [active]
431946006501	Zn binding site [ion binding]; other site
431946006502	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
431946006503	active site
431946006504	catalytic motif [active]
431946006505	Zn binding site [ion binding]; other site
431946006506	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
431946006507	putative active site [active]
431946006508	Protein of unknown function (DUF2542); Region: DUF2542; pfam10808
431946006509	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
431946006510	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
431946006511	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
431946006512	dihydropyrimidine dehydrogenase subunit B; Validated; Region: PRK08318
431946006513	Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain.  DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and...; Region: DHPD_FMN; cd02940
431946006514	homodimer interface [polypeptide binding]; other site
431946006515	active site
431946006516	FMN binding site [chemical binding]; other site
431946006517	substrate binding site [chemical binding]; other site
431946006518	4Fe-4S binding domain; Region: Fer4; pfam00037
431946006519	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
431946006520	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
431946006521	TM-ABC transporter signature motif; other site
431946006522	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
431946006523	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
431946006524	Walker A/P-loop; other site
431946006525	ATP binding site [chemical binding]; other site
431946006526	Q-loop/lid; other site
431946006527	ABC transporter signature motif; other site
431946006528	Walker B; other site
431946006529	D-loop; other site
431946006530	H-loop/switch region; other site
431946006531	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
431946006532	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
431946006533	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
431946006534	ligand binding site [chemical binding]; other site
431946006535	calcium binding site [ion binding]; other site
431946006536	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
431946006537	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
431946006538	DNA binding site [nucleotide binding]
431946006539	domain linker motif; other site
431946006540	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
431946006541	dimerization interface (closed form) [polypeptide binding]; other site
431946006542	ligand binding site [chemical binding]; other site
431946006543	Predicted membrane protein [Function unknown]; Region: COG2311
431946006544	hypothetical protein; Provisional; Region: PRK10835
431946006545	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
431946006546	homodecamer interface [polypeptide binding]; other site
431946006547	GTP cyclohydrolase I; Provisional; Region: PLN03044
431946006548	active site
431946006549	putative catalytic site residues [active]
431946006550	zinc binding site [ion binding]; other site
431946006551	GTP-CH-I/GFRP interaction surface; other site
431946006552	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
431946006553	S-formylglutathione hydrolase; Region: PLN02442
431946006554	catecholate siderophore receptor CirA; Provisional; Region: PRK10064
431946006555	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
431946006556	N-terminal plug; other site
431946006557	ligand-binding site [chemical binding]; other site
431946006558	lysine transporter; Provisional; Region: PRK10836
431946006559	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
431946006560	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946006561	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
431946006562	putative dimerization interface [polypeptide binding]; other site
431946006563	conserved hypothetical integral membrane protein; Region: TIGR00698
431946006564	endonuclease IV; Provisional; Region: PRK01060
431946006565	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
431946006566	AP (apurinic/apyrimidinic) site pocket; other site
431946006567	DNA interaction; other site
431946006568	Metal-binding active site; metal-binding site
431946006569	putative kinase; Provisional; Region: PRK09954
431946006570	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
431946006571	putative DNA binding site [nucleotide binding]; other site
431946006572	putative Zn2+ binding site [ion binding]; other site
431946006573	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
431946006574	substrate binding site [chemical binding]; other site
431946006575	ATP binding site [chemical binding]; other site
431946006576	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
431946006577	active site
431946006578	tetramer interface [polypeptide binding]; other site
431946006579	DNA-binding transcriptional activator YeiL; Provisional; Region: PRK10402
431946006580	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
431946006581	ligand binding site [chemical binding]; other site
431946006582	flexible hinge region; other site
431946006583	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
431946006584	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
431946006585	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
431946006586	Nucleoside recognition; Region: Gate; pfam07670
431946006587	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
431946006588	Indigoidine synthase A like protein; Region: Indigoidine_A; pfam04227
431946006589	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
431946006590	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
431946006591	substrate binding site [chemical binding]; other site
431946006592	ATP binding site [chemical binding]; other site
431946006593	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
431946006594	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
431946006595	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
431946006596	active site
431946006597	P-loop; other site
431946006598	phosphorylation site [posttranslational modification]
431946006599	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
431946006600	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
431946006601	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
431946006602	putative substrate binding site [chemical binding]; other site
431946006603	putative ATP binding site [chemical binding]; other site
431946006604	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
431946006605	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
431946006606	active site
431946006607	phosphorylation site [posttranslational modification]
431946006608	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
431946006609	dimerization domain swap beta strand [polypeptide binding]; other site
431946006610	regulatory protein interface [polypeptide binding]; other site
431946006611	active site
431946006612	regulatory phosphorylation site [posttranslational modification]; other site
431946006613	sugar efflux transporter B; Provisional; Region: PRK15011
431946006614	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946006615	putative substrate translocation pore; other site
431946006616	Flagellin N-methylase; Region: FliB; pfam03692
431946006617	elongation factor P; Provisional; Region: PRK04542
431946006618	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
431946006619	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
431946006620	RNA binding site [nucleotide binding]; other site
431946006621	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
431946006622	RNA binding site [nucleotide binding]; other site
431946006623	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
431946006624	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
431946006625	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
431946006626	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
431946006627	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
431946006628	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
431946006629	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
431946006630	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
431946006631	active site
431946006632	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
431946006633	NlpC/P60 family; Region: NLPC_P60; pfam00877
431946006634	phage resistance protein; Provisional; Region: PRK10551
431946006635	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
431946006636	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
431946006637	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
431946006638	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
431946006639	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
431946006640	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946006641	dimer interface [polypeptide binding]; other site
431946006642	conserved gate region; other site
431946006643	putative PBP binding loops; other site
431946006644	ABC-ATPase subunit interface; other site
431946006645	microcin C ABC transporter permease; Provisional; Region: PRK15021
431946006646	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946006647	dimer interface [polypeptide binding]; other site
431946006648	conserved gate region; other site
431946006649	ABC-ATPase subunit interface; other site
431946006650	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
431946006651	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
431946006652	Walker A/P-loop; other site
431946006653	ATP binding site [chemical binding]; other site
431946006654	Q-loop/lid; other site
431946006655	ABC transporter signature motif; other site
431946006656	Walker B; other site
431946006657	D-loop; other site
431946006658	H-loop/switch region; other site
431946006659	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
431946006660	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
431946006661	Walker A/P-loop; other site
431946006662	ATP binding site [chemical binding]; other site
431946006663	Q-loop/lid; other site
431946006664	ABC transporter signature motif; other site
431946006665	Walker B; other site
431946006666	D-loop; other site
431946006667	H-loop/switch region; other site
431946006668	hypothetical protein; Provisional; Region: PRK11835
431946006669	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946006670	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
431946006671	putative substrate translocation pore; other site
431946006672	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
431946006673	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
431946006674	RNA binding surface [nucleotide binding]; other site
431946006675	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
431946006676	active site
431946006677	uracil binding [chemical binding]; other site
431946006678	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
431946006679	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
431946006680	ATP binding site [chemical binding]; other site
431946006681	putative Mg++ binding site [ion binding]; other site
431946006682	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
431946006683	nucleotide binding region [chemical binding]; other site
431946006684	ATP-binding site [chemical binding]; other site
431946006685	Ribosomal L40e family; Region: Ribosomal_L40e; cl00671
431946006686	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
431946006687	5S rRNA interface [nucleotide binding]; other site
431946006688	CTC domain interface [polypeptide binding]; other site
431946006689	L16 interface [polypeptide binding]; other site
431946006690	Nucleoid-associated protein [General function prediction only]; Region: COG3081
431946006691	nucleoid-associated protein NdpA; Validated; Region: PRK00378
431946006692	hypothetical protein; Provisional; Region: PRK13689
431946006693	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
431946006694	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
431946006695	Sulfatase; Region: Sulfatase; pfam00884
431946006696	potential frameshift: common BLAST hit: gi|170019494|ref|YP_001724448.1| outer membrane autotransporter
431946006697	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cl00185
431946006698	transcriptional regulator NarP; Provisional; Region: PRK10403
431946006699	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946006700	active site
431946006701	phosphorylation site [posttranslational modification]
431946006702	intermolecular recognition site; other site
431946006703	dimerization interface [polypeptide binding]; other site
431946006704	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
431946006705	DNA binding residues [nucleotide binding]
431946006706	dimerization interface [polypeptide binding]; other site
431946006707	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
431946006708	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
431946006709	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
431946006710	binding surface
431946006711	TPR motif; other site
431946006712	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
431946006713	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
431946006714	catalytic residues [active]
431946006715	central insert; other site
431946006716	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
431946006717	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13165
431946006718	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
431946006719	heme exporter protein CcmC; Region: ccmC; TIGR01191
431946006720	heme exporter protein CcmB; Region: ccmB; TIGR01190
431946006721	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
431946006722	Cytochrome c biogenesis ATP-binding export protein; Region: ABC_CcmA_heme_exporter; cd03231
431946006723	Walker A/P-loop; other site
431946006724	ATP binding site [chemical binding]; other site
431946006725	Q-loop/lid; other site
431946006726	ABC transporter signature motif; other site
431946006727	Walker B; other site
431946006728	D-loop; other site
431946006729	H-loop/switch region; other site
431946006730	cytochrome c-type protein NapC; Provisional; Region: PRK10617
431946006731	Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit [Energy production and conversion]; Region: TorC; COG3005
431946006732	nitrate reductase cytochrome C550 subunit; Provisional; Region: napB; PRK11586
431946006733	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
431946006734	4Fe-4S binding domain; Region: Fer4_5; pfam12801
431946006735	4Fe-4S binding domain; Region: Fer4_6; pfam12837
431946006736	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
431946006737	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
431946006738	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
431946006739	[4Fe-4S] binding site [ion binding]; other site
431946006740	molybdopterin cofactor binding site; other site
431946006741	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
431946006742	molybdopterin cofactor binding site; other site
431946006743	assembly protein for periplasmic nitrate reductase; Provisional; Region: PRK10553
431946006744	ferredoxin-type protein; Provisional; Region: PRK10194
431946006745	tRNA synthetases class I (R); Region: tRNA-synt_1d; pfam00750
431946006746	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cd00242
431946006747	secondary substrate binding site; other site
431946006748	primary substrate binding site; other site
431946006749	inhibition loop; other site
431946006750	dimerization interface [polypeptide binding]; other site
431946006751	malate:quinone oxidoreductase; Validated; Region: PRK05257
431946006752	malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320
431946006753	multidrug transporter membrane component/ATP-binding component; Provisional; Region: PRK10522
431946006754	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
431946006755	Walker A/P-loop; other site
431946006756	ATP binding site [chemical binding]; other site
431946006757	Q-loop/lid; other site
431946006758	ABC transporter signature motif; other site
431946006759	Walker B; other site
431946006760	D-loop; other site
431946006761	H-loop/switch region; other site
431946006762	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
431946006763	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
431946006764	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
431946006765	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946006766	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
431946006767	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
431946006768	DNA binding site [nucleotide binding]
431946006769	active site
431946006770	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
431946006771	ApbE family; Region: ApbE; pfam02424
431946006772	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
431946006773	outer membrane porin protein C; Provisional; Region: PRK10554
431946006774	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
431946006775	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946006776	ATP binding site [chemical binding]; other site
431946006777	G-X-G motif; other site
431946006778	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
431946006779	putative binding surface; other site
431946006780	active site
431946006781	transcriptional regulator RcsB; Provisional; Region: PRK10840
431946006782	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946006783	active site
431946006784	phosphorylation site [posttranslational modification]
431946006785	intermolecular recognition site; other site
431946006786	dimerization interface [polypeptide binding]; other site
431946006787	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
431946006788	DNA binding residues [nucleotide binding]
431946006789	dimerization interface [polypeptide binding]; other site
431946006790	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
431946006791	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
431946006792	dimer interface [polypeptide binding]; other site
431946006793	phosphorylation site [posttranslational modification]
431946006794	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946006795	ATP binding site [chemical binding]; other site
431946006796	Mg2+ binding site [ion binding]; other site
431946006797	G-X-G motif; other site
431946006798	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
431946006799	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946006800	active site
431946006801	phosphorylation site [posttranslational modification]
431946006802	intermolecular recognition site; other site
431946006803	dimerization interface [polypeptide binding]; other site
431946006804	sensory histidine kinase AtoS; Provisional; Region: PRK11360
431946006805	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
431946006806	putative active site [active]
431946006807	heme pocket [chemical binding]; other site
431946006808	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
431946006809	dimer interface [polypeptide binding]; other site
431946006810	phosphorylation site [posttranslational modification]
431946006811	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946006812	ATP binding site [chemical binding]; other site
431946006813	Mg2+ binding site [ion binding]; other site
431946006814	G-X-G motif; other site
431946006815	acetoacetate metabolism regulatory protein AtoC; Provisional; Region: PRK11361
431946006816	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946006817	active site
431946006818	phosphorylation site [posttranslational modification]
431946006819	intermolecular recognition site; other site
431946006820	dimerization interface [polypeptide binding]; other site
431946006821	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946006822	Walker A motif; other site
431946006823	ATP binding site [chemical binding]; other site
431946006824	Walker B motif; other site
431946006825	arginine finger; other site
431946006826	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
431946006827	acetyl-CoA:acetoacetyl-CoA transferase subunit alpha; Provisional; Region: PRK09920
431946006828	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
431946006829	Short chain fatty acid transporter; Region: SCFA_trans; pfam02667
431946006830	putative acyltransferase; Provisional; Region: PRK05790
431946006831	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
431946006832	dimer interface [polypeptide binding]; other site
431946006833	active site
431946006834	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4676
431946006835	Uncharacterized protein conserved in bacteria (DUF2135); Region: DUF2135; pfam09906
431946006836	Predicted secreted protein [Function unknown]; Region: COG5445
431946006837	Predicted secreted protein (DUF2300); Region: DUF2300; pfam10062
431946006838	Predicted secreted protein [Function unknown]; Region: COG5445
431946006839	Stage II sporulation protein; Region: SpoIID; pfam08486
431946006840	Predicted secreted protein (DUF2300); Region: DUF2300; pfam10062
431946006841	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
431946006842	MG2 domain; Region: A2M_N; pfam01835
431946006843	Alpha-2-macroglobulin family; Region: A2M; pfam00207
431946006844	This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate...; Region: ISOPREN_C2_like; cl08267
431946006845	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3234
431946006846	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4685
431946006847	DNA gyrase subunit A; Validated; Region: PRK05560
431946006848	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
431946006849	CAP-like domain; other site
431946006850	active site
431946006851	primary dimer interface [polypeptide binding]; other site
431946006852	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
431946006853	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
431946006854	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
431946006855	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
431946006856	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
431946006857	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
431946006858	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
431946006859	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946006860	S-adenosylmethionine binding site [chemical binding]; other site
431946006861	adhesin; Provisional; Region: PRK09752
431946006862	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
431946006863	Autotransporter beta-domain; Region: Autotransporter; pfam03797
431946006864	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
431946006865	ATP cone domain; Region: ATP-cone; pfam03477
431946006866	Class I ribonucleotide reductase; Region: RNR_I; cd01679
431946006867	active site
431946006868	dimer interface [polypeptide binding]; other site
431946006869	catalytic residues [active]
431946006870	effector binding site; other site
431946006871	R2 peptide binding site; other site
431946006872	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
431946006873	dimer interface [polypeptide binding]; other site
431946006874	putative radical transfer pathway; other site
431946006875	diiron center [ion binding]; other site
431946006876	tyrosyl radical; other site
431946006877	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
431946006878	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
431946006879	catalytic loop [active]
431946006880	iron binding site [ion binding]; other site
431946006881	hypothetical protein; Provisional; Region: PRK09902
431946006882	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
431946006883	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
431946006884	active site
431946006885	catalytic site [active]
431946006886	metal binding site [ion binding]; metal-binding site
431946006887	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
431946006888	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946006889	putative substrate translocation pore; other site
431946006890	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
431946006891	hydroxyglutarate oxidase; Provisional; Region: PRK11728
431946006892	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
431946006893	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; COG3075
431946006894	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
431946006895	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
431946006896	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
431946006897	Cysteine-rich domain; Region: CCG; pfam02754
431946006898	Cysteine-rich domain; Region: CCG; pfam02754
431946006899	hypothetical protein; Provisional; Region: PRK09956
431946006900	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
431946006901	2-keto-3-deoxy-L-rhamnonate aldolase; Provisional; Region: PRK10128
431946006902	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
431946006903	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946006904	putative substrate translocation pore; other site
431946006905	L-rhamnonate dehydratase; Provisional; Region: PRK15440
431946006906	Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 2. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic...; Region: MR_like_2; cd03327
431946006907	putative active site pocket [active]
431946006908	putative metal binding site [ion binding]; other site
431946006909	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
431946006910	Transcriptional regulator [Transcription]; Region: IclR; COG1414
431946006911	Bacterial transcriptional regulator; Region: IclR; pfam01614
431946006912	hypothetical protein; Provisional; Region: PRK03673
431946006913	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
431946006914	putative MPT binding site; other site
431946006915	Competence-damaged protein; Region: CinA; cl00666
431946006916	YfaZ precursor; Region: YfaZ; pfam07437
431946006917	outer membrane protein; Region: OMP_w_GlyGly; TIGR04219
431946006918	nucleoside triphosphatase NudI; Provisional; Region: PRK15472
431946006919	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
431946006920	catalytic core [active]
431946006921	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
431946006922	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
431946006923	inhibitor-cofactor binding pocket; inhibition site
431946006924	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946006925	catalytic residue [active]
431946006926	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
431946006927	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
431946006928	Ligand binding site; other site
431946006929	Putative Catalytic site; other site
431946006930	DXD motif; other site
431946006931	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
431946006932	ArnA, N-terminal formyltransferase domain; Region: FMT_core_ArnA_N; cd08644
431946006933	substrate binding site [chemical binding]; other site
431946006934	cosubstrate binding site; other site
431946006935	catalytic site [active]
431946006936	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
431946006937	active site
431946006938	hexamer interface [polypeptide binding]; other site
431946006939	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
431946006940	NAD binding site [chemical binding]; other site
431946006941	substrate binding site [chemical binding]; other site
431946006942	active site
431946006943	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
431946006944	Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939
431946006945	putative active site [active]
431946006946	putative catalytic site [active]
431946006947	putative Zn binding site [ion binding]; other site
431946006948	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
431946006949	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
431946006950	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
431946006951	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
431946006952	signal transduction protein PmrD; Provisional; Region: PRK15450
431946006953	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
431946006954	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
431946006955	acyl-activating enzyme (AAE) consensus motif; other site
431946006956	putative AMP binding site [chemical binding]; other site
431946006957	putative active site [active]
431946006958	putative CoA binding site [chemical binding]; other site
431946006959	O-succinylbenzoate synthase; Provisional; Region: PRK05105
431946006960	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
431946006961	active site
431946006962	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
431946006963	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
431946006964	substrate binding site [chemical binding]; other site
431946006965	oxyanion hole (OAH) forming residues; other site
431946006966	trimer interface [polypeptide binding]; other site
431946006967	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
431946006968	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
431946006969	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
431946006970	dimer interface [polypeptide binding]; other site
431946006971	tetramer interface [polypeptide binding]; other site
431946006972	PYR/PP interface [polypeptide binding]; other site
431946006973	TPP binding site [chemical binding]; other site
431946006974	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
431946006975	TPP-binding site; other site
431946006976	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
431946006977	isochorismate synthases; Region: isochor_syn; TIGR00543
431946006978	hypothetical protein; Provisional; Region: PRK10404
431946006979	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
431946006980	Coenzyme A binding pocket [chemical binding]; other site
431946006981	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
431946006982	von Willebrand factor; Region: vWF_A; pfam12450
431946006983	Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only]; Region: COG2304
431946006984	VWA subgroup: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subgroup; cd01465
431946006985	metal ion-dependent adhesion site (MIDAS); other site
431946006986	Domain of unknown function (DUF3520); Region: DUF3520; pfam12034
431946006987	M28 Zn-Peptidases; Region: M28_like_1; cd05640
431946006988	Peptidase family M28; Region: Peptidase_M28; pfam04389
431946006989	metal binding site [ion binding]; metal-binding site
431946006990	Domain of unknown function (DUF1877); Region: DUF1877; pfam08974
431946006991	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
431946006992	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
431946006993	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
431946006994	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
431946006995	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
431946006996	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
431946006997	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
431946006998	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
431946006999	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
431946007000	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
431946007001	4Fe-4S binding domain; Region: Fer4; pfam00037
431946007002	4Fe-4S binding domain; Region: Fer4; pfam00037
431946007003	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
431946007004	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
431946007005	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
431946007006	catalytic loop [active]
431946007007	iron binding site [ion binding]; other site
431946007008	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
431946007009	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
431946007010	[4Fe-4S] binding site [ion binding]; other site
431946007011	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
431946007012	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
431946007013	SLBB domain; Region: SLBB; pfam10531
431946007014	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
431946007015	NADH dehydrogenase subunit E; Validated; Region: PRK07539
431946007016	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
431946007017	putative dimer interface [polypeptide binding]; other site
431946007018	[2Fe-2S] cluster binding site [ion binding]; other site
431946007019	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
431946007020	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
431946007021	NADH dehydrogenase subunit D; Validated; Region: PRK06075
431946007022	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
431946007023	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
431946007024	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
431946007025	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946007026	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
431946007027	putative dimerization interface [polypeptide binding]; other site
431946007028	aminotransferase AlaT; Validated; Region: PRK09265
431946007029	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
431946007030	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946007031	homodimer interface [polypeptide binding]; other site
431946007032	catalytic residue [active]
431946007033	5'-nucleotidase; Provisional; Region: PRK03826
431946007034	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
431946007035	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
431946007036	TrkA-C domain; Region: TrkA_C; pfam02080
431946007037	TrkA-C domain; Region: TrkA_C; pfam02080
431946007038	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
431946007039	putative phosphatase; Provisional; Region: PRK11587
431946007040	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
431946007041	motif II; other site
431946007042	hypothetical protein; Validated; Region: PRK05445
431946007043	hypothetical protein; Provisional; Region: PRK01816
431946007044	propionate/acetate kinase; Provisional; Region: PRK12379
431946007045	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
431946007046	phosphate acetyltransferase; Reviewed; Region: PRK05632
431946007047	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
431946007048	DRTGG domain; Region: DRTGG; pfam07085
431946007049	phosphate acetyltransferase; Region: pta; TIGR00651
431946007050	hypothetical protein; Provisional; Region: PRK11588
431946007051	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
431946007052	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
431946007053	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
431946007054	nudix motif; other site
431946007055	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
431946007056	active site
431946007057	metal binding site [ion binding]; metal-binding site
431946007058	homotetramer interface [polypeptide binding]; other site
431946007059	glutathione S-transferase; Provisional; Region: PRK15113
431946007060	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
431946007061	C-terminal domain interface [polypeptide binding]; other site
431946007062	GSH binding site (G-site) [chemical binding]; other site
431946007063	dimer interface [polypeptide binding]; other site
431946007064	C-terminal, alpha helical domain of an unknown subfamily 4 of Glutathione S-transferases; Region: GST_C_4; cd03195
431946007065	N-terminal domain interface [polypeptide binding]; other site
431946007066	putative dimer interface [polypeptide binding]; other site
431946007067	putative substrate binding pocket (H-site) [chemical binding]; other site
431946007068	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
431946007069	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
431946007070	C-terminal domain interface [polypeptide binding]; other site
431946007071	GSH binding site (G-site) [chemical binding]; other site
431946007072	dimer interface [polypeptide binding]; other site
431946007073	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
431946007074	N-terminal domain interface [polypeptide binding]; other site
431946007075	putative dimer interface [polypeptide binding]; other site
431946007076	active site
431946007077	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
431946007078	homooctamer interface [polypeptide binding]; other site
431946007079	active site
431946007080	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
431946007081	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
431946007082	putative NAD(P) binding site [chemical binding]; other site
431946007083	putative active site [active]
431946007084	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
431946007085	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
431946007086	Walker A/P-loop; other site
431946007087	ATP binding site [chemical binding]; other site
431946007088	Q-loop/lid; other site
431946007089	ABC transporter signature motif; other site
431946007090	Walker B; other site
431946007091	D-loop; other site
431946007092	H-loop/switch region; other site
431946007093	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946007094	dimer interface [polypeptide binding]; other site
431946007095	conserved gate region; other site
431946007096	putative PBP binding loops; other site
431946007097	ABC-ATPase subunit interface; other site
431946007098	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
431946007099	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946007100	dimer interface [polypeptide binding]; other site
431946007101	conserved gate region; other site
431946007102	putative PBP binding loops; other site
431946007103	ABC-ATPase subunit interface; other site
431946007104	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
431946007105	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
431946007106	substrate binding pocket [chemical binding]; other site
431946007107	membrane-bound complex binding site; other site
431946007108	hinge residues; other site
431946007109	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
431946007110	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
431946007111	substrate binding pocket [chemical binding]; other site
431946007112	membrane-bound complex binding site; other site
431946007113	hinge residues; other site
431946007114	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
431946007115	Flavoprotein; Region: Flavoprotein; pfam02441
431946007116	amidophosphoribosyltransferase; Provisional; Region: PRK09246
431946007117	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
431946007118	active site
431946007119	tetramer interface [polypeptide binding]; other site
431946007120	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
431946007121	active site
431946007122	colicin V production protein; Provisional; Region: PRK10845
431946007123	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
431946007124	cell division protein DedD; Provisional; Region: PRK11633
431946007125	Sporulation related domain; Region: SPOR; pfam05036
431946007126	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
431946007127	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
431946007128	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
431946007129	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
431946007130	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
431946007131	hypothetical protein; Provisional; Region: PRK10847
431946007132	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
431946007133	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
431946007134	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
431946007135	dimerization interface 3.5A [polypeptide binding]; other site
431946007136	active site
431946007137	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
431946007138	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
431946007139	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
431946007140	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
431946007141	ligand binding site [chemical binding]; other site
431946007142	NAD binding site [chemical binding]; other site
431946007143	catalytic site [active]
431946007144	homodimer interface [polypeptide binding]; other site
431946007145	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
431946007146	putative transporter; Provisional; Region: PRK12382
431946007147	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946007148	putative substrate translocation pore; other site
431946007149	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
431946007150	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
431946007151	dimer interface [polypeptide binding]; other site
431946007152	active site
431946007153	Uncharacterized conserved protein [Function unknown]; Region: COG4121
431946007154	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
431946007155	YfcL protein; Region: YfcL; pfam08891
431946007156	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3101
431946007157	hypothetical protein; Provisional; Region: PRK10621
431946007158	Predicted permeases [General function prediction only]; Region: COG0730
431946007159	Murein endopeptidase [Cell envelope biogenesis, outer membrane]; Region: MepA; COG3770
431946007160	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
431946007161	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
431946007162	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
431946007163	Tetramer interface [polypeptide binding]; other site
431946007164	active site
431946007165	FMN-binding site [chemical binding]; other site
431946007166	HemK family putative methylases; Region: hemK_fam; TIGR00536
431946007167	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946007168	S-adenosylmethionine binding site [chemical binding]; other site
431946007169	hypothetical protein; Provisional; Region: PRK04946
431946007170	Smr domain; Region: Smr; pfam01713
431946007171	Protein of unknown function (DUF2544); Region: DUF2544; pfam11245
431946007172	Fimbrial protein; Region: Fimbrial; cl01416
431946007173	Fimbrial protein; Region: Fimbrial; cl01416
431946007174	Fimbrial protein; Region: Fimbrial; cl01416
431946007175	fimbrial chaperone protein StdC; Provisional; Region: PRK15254
431946007176	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
431946007177	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
431946007178	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
431946007179	PapC N-terminal domain; Region: PapC_N; pfam13954
431946007180	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
431946007181	PapC C-terminal domain; Region: PapC_C; pfam13953
431946007182	Fimbrial protein; Region: Fimbrial; cl01416
431946007183	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
431946007184	catalytic core [active]
431946007185	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
431946007186	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
431946007187	substrate binding site [chemical binding]; other site
431946007188	oxyanion hole (OAH) forming residues; other site
431946007189	trimer interface [polypeptide binding]; other site
431946007190	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
431946007191	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
431946007192	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
431946007193	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
431946007194	dimer interface [polypeptide binding]; other site
431946007195	active site
431946007196	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
431946007197	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
431946007198	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
431946007199	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
431946007200	integrase; Provisional; Region: PRK09692
431946007201	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
431946007202	active site
431946007203	Int/Topo IB signature motif; other site
431946007204	SPRY domain; Region: SPRY; cl02614
431946007205	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
431946007206	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4643
431946007207	Zinc-binding domain of primase-helicase; Region: Prim_Zn_Ribbon; smart00778
431946007208	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
431946007209	active site
431946007210	metal binding site [ion binding]; metal-binding site
431946007211	interdomain interaction site; other site
431946007212	Domain of unknown function (DUF927); Region: DUF927; pfam06048
431946007213	Ash protein family; Region: Phage_ASH; pfam10554
431946007214	Phage major capsid protein, P2 family; Region: Phage_cap_P2; cl04947
431946007215	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
431946007216	DNA-binding transcriptional regulator DsdC; Provisional; Region: PRK10086
431946007217	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946007218	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
431946007219	dimerization interface [polypeptide binding]; other site
431946007220	substrate binding pocket [chemical binding]; other site
431946007221	permease DsdX; Provisional; Region: PRK09921
431946007222	gluconate transporter; Region: gntP; TIGR00791
431946007223	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
431946007224	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
431946007225	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
431946007226	catalytic residue [active]
431946007227	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
431946007228	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946007229	putative substrate translocation pore; other site
431946007230	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946007231	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
431946007232	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
431946007233	HlyD family secretion protein; Region: HlyD_3; pfam13437
431946007234	DNA-binding transcriptional activator EvgA; Provisional; Region: PRK09958
431946007235	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946007236	active site
431946007237	phosphorylation site [posttranslational modification]
431946007238	intermolecular recognition site; other site
431946007239	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
431946007240	DNA binding residues [nucleotide binding]
431946007241	dimerization interface [polypeptide binding]; other site
431946007242	hybrid sensory histidine kinase in two-component regulatory system with EvgA; Provisional; Region: PRK09959
431946007243	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
431946007244	substrate binding pocket [chemical binding]; other site
431946007245	membrane-bound complex binding site; other site
431946007246	hinge residues; other site
431946007247	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
431946007248	substrate binding pocket [chemical binding]; other site
431946007249	membrane-bound complex binding site; other site
431946007250	hinge residues; other site
431946007251	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
431946007252	dimer interface [polypeptide binding]; other site
431946007253	phosphorylation site [posttranslational modification]
431946007254	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946007255	ATP binding site [chemical binding]; other site
431946007256	Mg2+ binding site [ion binding]; other site
431946007257	G-X-G motif; other site
431946007258	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946007259	active site
431946007260	phosphorylation site [posttranslational modification]
431946007261	intermolecular recognition site; other site
431946007262	dimerization interface [polypeptide binding]; other site
431946007263	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
431946007264	putative binding surface; other site
431946007265	active site
431946007266	putative CoA-transferase; Provisional; Region: PRK11430
431946007267	CoA-transferase family III; Region: CoA_transf_3; pfam02515
431946007268	putative transporter YfdV; Provisional; Region: PRK09903
431946007269	putative oxalyl-CoA decarboxylase; Validated; Region: PRK09259
431946007270	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
431946007271	PYR/PP interface [polypeptide binding]; other site
431946007272	dimer interface [polypeptide binding]; other site
431946007273	TPP binding site [chemical binding]; other site
431946007274	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
431946007275	Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of proteins similar to benzaldehyde lyase (BZL), oxalyl-CoA decarboxylase (OCoD) and 2-hydroxyphytanoyl-CoA lyase (2-HPCL). Pseudomonas fluorescens biovar I BZL...; Region: TPP_BZL_OCoD_HPCL; cd02004
431946007276	TPP-binding site; other site
431946007277	dimer interface [polypeptide binding]; other site
431946007278	formyl-coenzyme A transferase; Provisional; Region: PRK05398
431946007279	CoA-transferase family III; Region: CoA_transf_3; pfam02515
431946007280	hypothetical protein; Provisional; Region: PRK10316
431946007281	YfdX protein; Region: YfdX; pfam10938
431946007282	Protein of unknown function (DUF2545); Region: DUF2545; pfam10810
431946007283	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
431946007284	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
431946007285	putative acyl-acceptor binding pocket; other site
431946007286	aminotransferase; Validated; Region: PRK08175
431946007287	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
431946007288	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946007289	homodimer interface [polypeptide binding]; other site
431946007290	catalytic residue [active]
431946007291	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
431946007292	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
431946007293	GAF domain; Region: GAF; cl17456
431946007294	Histidine kinase; Region: His_kinase; pfam06580
431946007295	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946007296	ATP binding site [chemical binding]; other site
431946007297	Mg2+ binding site [ion binding]; other site
431946007298	G-X-G motif; other site
431946007299	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
431946007300	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946007301	active site
431946007302	phosphorylation site [posttranslational modification]
431946007303	intermolecular recognition site; other site
431946007304	dimerization interface [polypeptide binding]; other site
431946007305	LytTr DNA-binding domain; Region: LytTR; pfam04397
431946007306	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
431946007307	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946007308	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
431946007309	dimerization domain swap beta strand [polypeptide binding]; other site
431946007310	regulatory protein interface [polypeptide binding]; other site
431946007311	active site
431946007312	regulatory phosphorylation site [posttranslational modification]; other site
431946007313	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
431946007314	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
431946007315	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
431946007316	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
431946007317	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
431946007318	active site
431946007319	phosphorylation site [posttranslational modification]
431946007320	exoaminopeptidase; Provisional; Region: PRK09961
431946007321	M42 Peptidases, also known as glutamyl aminopeptidase family; Region: M42; cd05638
431946007322	oligomer interface [polypeptide binding]; other site
431946007323	active site
431946007324	metal binding site [ion binding]; metal-binding site
431946007325	aminopeptidase; Provisional; Region: PRK09795
431946007326	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
431946007327	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
431946007328	active site
431946007329	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
431946007330	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
431946007331	active site
431946007332	P-loop; other site
431946007333	phosphorylation site [posttranslational modification]
431946007334	glucokinase, proteobacterial type; Region: glk; TIGR00749
431946007335	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
431946007336	nucleotide binding site [chemical binding]; other site
431946007337	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
431946007338	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
431946007339	Cl- selectivity filter; other site
431946007340	Cl- binding residues [ion binding]; other site
431946007341	pore gating glutamate residue; other site
431946007342	dimer interface [polypeptide binding]; other site
431946007343	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
431946007344	manganese transport protein MntH; Reviewed; Region: PRK00701
431946007345	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
431946007346	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
431946007347	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
431946007348	Nucleoside recognition; Region: Gate; pfam07670
431946007349	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
431946007350	MASE1; Region: MASE1; pfam05231
431946007351	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
431946007352	diguanylate cyclase; Region: GGDEF; smart00267
431946007353	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
431946007354	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
431946007355	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
431946007356	salt bridge; other site
431946007357	non-specific DNA binding site [nucleotide binding]; other site
431946007358	sequence-specific DNA binding site [nucleotide binding]; other site
431946007359	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
431946007360	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
431946007361	active site
431946007362	HIGH motif; other site
431946007363	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
431946007364	active site
431946007365	KMSKS motif; other site
431946007366	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
431946007367	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946007368	The C-terminal substrate binding domain of LysR-type transcriptional regulator XapR involved in xanthosine catabolism, contains the type 2 periplasmic binding fold; Region: PBP2_XapR; cd08449
431946007369	putative dimerization interface [polypeptide binding]; other site
431946007370	putative substrate binding pocket [chemical binding]; other site
431946007371	XapX domain; Region: XapX; TIGR03510
431946007372	nucleoside transporter; Region: 2A0110; TIGR00889
431946007373	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946007374	putative substrate translocation pore; other site
431946007375	purine nucleoside phosphorylase; Provisional; Region: PRK08202
431946007376	hypothetical protein; Provisional; Region: PRK11528
431946007377	Transcriptional regulator [Transcription]; Region: LysR; COG0583
431946007378	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946007379	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
431946007380	putative dimerization interface [polypeptide binding]; other site
431946007381	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
431946007382	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
431946007383	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3530
431946007384	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
431946007385	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
431946007386	nucleotide binding pocket [chemical binding]; other site
431946007387	K-X-D-G motif; other site
431946007388	catalytic site [active]
431946007389	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
431946007390	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
431946007391	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
431946007392	Dimer interface [polypeptide binding]; other site
431946007393	BRCT sequence motif; other site
431946007394	cell division protein ZipA; Provisional; Region: PRK03427
431946007395	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cl12038
431946007396	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
431946007397	FtsZ protein binding site [polypeptide binding]; other site
431946007398	putative sulfate transport protein CysZ; Validated; Region: PRK04949
431946007399	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
431946007400	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
431946007401	dimer interface [polypeptide binding]; other site
431946007402	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946007403	catalytic residue [active]
431946007404	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
431946007405	dimerization domain swap beta strand [polypeptide binding]; other site
431946007406	regulatory protein interface [polypeptide binding]; other site
431946007407	active site
431946007408	regulatory phosphorylation site [posttranslational modification]; other site
431946007409	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
431946007410	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
431946007411	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
431946007412	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
431946007413	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
431946007414	HPr interaction site; other site
431946007415	glycerol kinase (GK) interaction site [polypeptide binding]; other site
431946007416	active site
431946007417	phosphorylation site [posttranslational modification]
431946007418	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
431946007419	dimer interface [polypeptide binding]; other site
431946007420	pyridoxamine kinase; Validated; Region: PRK05756
431946007421	pyridoxal binding site [chemical binding]; other site
431946007422	ATP binding site [chemical binding]; other site
431946007423	hypothetical protein; Provisional; Region: PRK10318
431946007424	cysteine synthase B; Region: cysM; TIGR01138
431946007425	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
431946007426	dimer interface [polypeptide binding]; other site
431946007427	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946007428	catalytic residue [active]
431946007429	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
431946007430	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
431946007431	Walker A/P-loop; other site
431946007432	ATP binding site [chemical binding]; other site
431946007433	Q-loop/lid; other site
431946007434	ABC transporter signature motif; other site
431946007435	Walker B; other site
431946007436	D-loop; other site
431946007437	H-loop/switch region; other site
431946007438	TOBE-like domain; Region: TOBE_3; pfam12857
431946007439	sulfate transport protein; Provisional; Region: cysT; CHL00187
431946007440	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946007441	dimer interface [polypeptide binding]; other site
431946007442	conserved gate region; other site
431946007443	putative PBP binding loops; other site
431946007444	ABC-ATPase subunit interface; other site
431946007445	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
431946007446	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946007447	dimer interface [polypeptide binding]; other site
431946007448	conserved gate region; other site
431946007449	putative PBP binding loops; other site
431946007450	ABC-ATPase subunit interface; other site
431946007451	thiosulfate transporter subunit; Provisional; Region: PRK10852
431946007452	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
431946007453	short chain dehydrogenase; Provisional; Region: PRK08226
431946007454	human DHRS6-like, classical (c) SDRs; Region: DHRS6_like_SDR_c; cd05368
431946007455	NAD binding site [chemical binding]; other site
431946007456	homotetramer interface [polypeptide binding]; other site
431946007457	homodimer interface [polypeptide binding]; other site
431946007458	active site
431946007459	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
431946007460	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
431946007461	putative active site [active]
431946007462	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
431946007463	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
431946007464	active site turn [active]
431946007465	phosphorylation site [posttranslational modification]
431946007466	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
431946007467	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
431946007468	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
431946007469	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
431946007470	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
431946007471	putative acetyltransferase; Provisional; Region: PRK03624
431946007472	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
431946007473	Coenzyme A binding pocket [chemical binding]; other site
431946007474	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
431946007475	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
431946007476	active site
431946007477	metal binding site [ion binding]; metal-binding site
431946007478	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
431946007479	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
431946007480	transcriptional regulator EutR; Provisional; Region: PRK10130
431946007481	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946007482	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946007483	carboxysome structural protein EutK; Provisional; Region: PRK15466
431946007484	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
431946007485	Hexamer interface [polypeptide binding]; other site
431946007486	Hexagonal pore residue; other site
431946007487	ethanolamine utilization protein EutL; Provisional; Region: PRK15405
431946007488	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_EutL_repeat1; cd07049
431946007489	putative hexamer interface [polypeptide binding]; other site
431946007490	putative hexagonal pore; other site
431946007491	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_EutL_repeat2; cd07050
431946007492	putative hexamer interface [polypeptide binding]; other site
431946007493	putative hexagonal pore; other site
431946007494	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
431946007495	Ethanolamine ammonia-lyase, large subunit [Amino acid transport and metabolism]; Region: EutB; COG4303
431946007496	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
431946007497	reactivating factor for ethanolamine ammonia lyase; Provisional; Region: eutA; PRK10719
431946007498	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutH; COG3192
431946007499	ethanol dehydrogenase EutG; Provisional; Region: PRK15454
431946007500	iron-containing alcohol dehydrogenases (Fe-ADH)-like; Region: Fe-ADH; cd08551
431946007501	active site
431946007502	metal binding site [ion binding]; metal-binding site
431946007503	Ethanolamine utilization protein, possible chaperonin [Amino acid transport and metabolism]; Region: EutJ; COG4820
431946007504	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
431946007505	nucleotide binding site [chemical binding]; other site
431946007506	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
431946007507	putative catalytic cysteine [active]
431946007508	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
431946007509	Hexamer/Pentamer interface [polypeptide binding]; other site
431946007510	central pore; other site
431946007511	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
431946007512	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
431946007513	Hexamer interface [polypeptide binding]; other site
431946007514	Putative hexagonal pore residue; other site
431946007515	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
431946007516	ethanolamine utilization cobalamin adenosyltransferase; Provisional; Region: PRK15020
431946007517	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
431946007518	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutQ; COG4766
431946007519	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
431946007520	G1 box; other site
431946007521	GTP/Mg2+ binding site [chemical binding]; other site
431946007522	G2 box; other site
431946007523	Switch I region; other site
431946007524	G3 box; other site
431946007525	Switch II region; other site
431946007526	G4 box; other site
431946007527	G5 box; other site
431946007528	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
431946007529	putative hexamer interface [polypeptide binding]; other site
431946007530	putative hexagonal pore; other site
431946007531	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
431946007532	Malic enzyme, N-terminal domain; Region: malic; pfam00390
431946007533	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
431946007534	putative NAD(P) binding site [chemical binding]; other site
431946007535	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
431946007536	transaldolase-like protein; Provisional; Region: PTZ00411
431946007537	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
431946007538	active site
431946007539	dimer interface [polypeptide binding]; other site
431946007540	catalytic residue [active]
431946007541	transketolase; Reviewed; Region: PRK12753
431946007542	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
431946007543	TPP-binding site [chemical binding]; other site
431946007544	dimer interface [polypeptide binding]; other site
431946007545	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
431946007546	PYR/PP interface [polypeptide binding]; other site
431946007547	dimer interface [polypeptide binding]; other site
431946007548	TPP binding site [chemical binding]; other site
431946007549	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
431946007550	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
431946007551	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
431946007552	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
431946007553	dimer interface [polypeptide binding]; other site
431946007554	ADP-ribose binding site [chemical binding]; other site
431946007555	active site
431946007556	nudix motif; other site
431946007557	metal binding site [ion binding]; metal-binding site
431946007558	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12769
431946007559	4Fe-4S binding domain; Region: Fer4; pfam00037
431946007560	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
431946007561	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
431946007562	nitrate/nitrite sensor protein NarQ; Provisional; Region: PRK10935
431946007563	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
431946007564	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
431946007565	dimerization interface [polypeptide binding]; other site
431946007566	Histidine kinase; Region: HisKA_3; pfam07730
431946007567	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946007568	ATP binding site [chemical binding]; other site
431946007569	Mg2+ binding site [ion binding]; other site
431946007570	G-X-G motif; other site
431946007571	aminoglycoside/multidrug efflux system; Provisional; Region: PRK10555
431946007572	Protein export membrane protein; Region: SecD_SecF; cl14618
431946007573	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
431946007574	ArsC family; Region: ArsC; pfam03960
431946007575	putative catalytic residues [active]
431946007576	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
431946007577	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
431946007578	metal binding site [ion binding]; metal-binding site
431946007579	dimer interface [polypeptide binding]; other site
431946007580	hypothetical protein; Provisional; Region: PRK13664
431946007581	putative hydrolase; Provisional; Region: PRK11460
431946007582	Phospholipase/Carboxylesterase; Region: Abhydrolase_2; pfam02230
431946007583	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
431946007584	Domain of unknown function (DUF1726); Region: DUF1726; pfam08351
431946007585	Helicase; Region: Helicase_RecD; pfam05127
431946007586	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
431946007587	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
431946007588	Predicted metalloprotease [General function prediction only]; Region: COG2321
431946007589	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
431946007590	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
431946007591	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
431946007592	ATP binding site [chemical binding]; other site
431946007593	active site
431946007594	substrate binding site [chemical binding]; other site
431946007595	lipoprotein; Provisional; Region: PRK11679
431946007596	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
431946007597	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
431946007598	dihydrodipicolinate synthase; Region: dapA; TIGR00674
431946007599	dimer interface [polypeptide binding]; other site
431946007600	active site
431946007601	catalytic residue [active]
431946007602	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
431946007603	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
431946007604	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
431946007605	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
431946007606	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
431946007607	catalytic triad [active]
431946007608	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
431946007609	Domain of unknown function DUF20; Region: UPF0118; pfam01594
431946007610	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
431946007611	Peptidase family M48; Region: Peptidase_M48; cl12018
431946007612	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
431946007613	ArsC family; Region: ArsC; pfam03960
431946007614	catalytic residues [active]
431946007615	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
431946007616	DNA replication initiation factor; Provisional; Region: PRK08084
431946007617	uracil transporter; Provisional; Region: PRK10720
431946007618	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
431946007619	active site
431946007620	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
431946007621	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
431946007622	dimerization interface [polypeptide binding]; other site
431946007623	putative ATP binding site [chemical binding]; other site
431946007624	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
431946007625	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
431946007626	active site
431946007627	substrate binding site [chemical binding]; other site
431946007628	cosubstrate binding site; other site
431946007629	catalytic site [active]
431946007630	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
431946007631	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
431946007632	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
431946007633	Catalytic C-terminal domain, first repeat, of prokaryotic polyphosphate kinase 1 and similar proteins; Region: PLDc_PPK1_C1; cd09114
431946007634	domain interface [polypeptide binding]; other site
431946007635	active site
431946007636	catalytic site [active]
431946007637	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
431946007638	putative active site [active]
431946007639	catalytic site [active]
431946007640	exopolyphosphatase; Provisional; Region: PRK10854
431946007641	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
431946007642	MASE1; Region: MASE1; pfam05231
431946007643	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
431946007644	diguanylate cyclase; Region: GGDEF; smart00267
431946007645	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
431946007646	Glycine zipper 2TM domain; Region: Rick_17kDa_Anti; cl10470
431946007647	GMP synthase; Reviewed; Region: guaA; PRK00074
431946007648	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
431946007649	AMP/PPi binding site [chemical binding]; other site
431946007650	candidate oxyanion hole; other site
431946007651	catalytic triad [active]
431946007652	potential glutamine specificity residues [chemical binding]; other site
431946007653	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
431946007654	ATP Binding subdomain [chemical binding]; other site
431946007655	Ligand Binding sites [chemical binding]; other site
431946007656	Dimerization subdomain; other site
431946007657	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
431946007658	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
431946007659	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
431946007660	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
431946007661	active site
431946007662	exodeoxyribonuclease VII, large subunit; Region: xseA; TIGR00237
431946007663	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
431946007664	generic binding surface II; other site
431946007665	generic binding surface I; other site
431946007666	RatA-like protein; Provisional; Region: PRK15316
431946007667	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
431946007668	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
431946007669	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
431946007670	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
431946007671	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
431946007672	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
431946007673	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
431946007674	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
431946007675	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
431946007676	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
431946007677	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
431946007678	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
431946007679	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
431946007680	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
431946007681	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
431946007682	Salmonella repeat of unknown function (DUF824); Region: DUF824; pfam05688
431946007683	Salmonella repeat of unknown function (DUF823); Region: DUF823; pfam05689
431946007684	intimin-like protein SinH; Provisional; Region: PRK15318
431946007685	intimin-like protein SinH; Provisional; Region: PRK15318
431946007686	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
431946007687	Protein of unknown function (DUF1407); Region: DUF1407; pfam07191
431946007688	GTP-binding protein Der; Reviewed; Region: PRK00093
431946007689	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
431946007690	G1 box; other site
431946007691	GTP/Mg2+ binding site [chemical binding]; other site
431946007692	Switch I region; other site
431946007693	G2 box; other site
431946007694	Switch II region; other site
431946007695	G3 box; other site
431946007696	G4 box; other site
431946007697	G5 box; other site
431946007698	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
431946007699	G1 box; other site
431946007700	GTP/Mg2+ binding site [chemical binding]; other site
431946007701	Switch I region; other site
431946007702	G2 box; other site
431946007703	G3 box; other site
431946007704	Switch II region; other site
431946007705	G4 box; other site
431946007706	G5 box; other site
431946007707	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
431946007708	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
431946007709	Trp docking motif [polypeptide binding]; other site
431946007710	active site
431946007711	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
431946007712	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
431946007713	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
431946007714	dimer interface [polypeptide binding]; other site
431946007715	motif 1; other site
431946007716	active site
431946007717	motif 2; other site
431946007718	motif 3; other site
431946007719	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
431946007720	anticodon binding site; other site
431946007721	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
431946007722	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
431946007723	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
431946007724	cytoskeletal protein RodZ; Provisional; Region: PRK10856
431946007725	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
431946007726	non-specific DNA binding site [nucleotide binding]; other site
431946007727	salt bridge; other site
431946007728	sequence-specific DNA binding site [nucleotide binding]; other site
431946007729	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
431946007730	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
431946007731	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
431946007732	FeS/SAM binding site; other site
431946007733	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
431946007734	active site
431946007735	multimer interface [polypeptide binding]; other site
431946007736	penicillin-binding protein 1C; Provisional; Region: PRK11240
431946007737	Transglycosylase; Region: Transgly; pfam00912
431946007738	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
431946007739	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
431946007740	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
431946007741	MG2 domain; Region: A2M_N; pfam01835
431946007742	Alpha-2-macroglobulin family; Region: A2M; pfam00207
431946007743	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
431946007744	surface patch; other site
431946007745	thioester region; other site
431946007746	specificity defining residues; other site
431946007747	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
431946007748	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
431946007749	active site residue [active]
431946007750	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
431946007751	active site residue [active]
431946007752	enhanced serine sensitivity protein SseB; Provisional; Region: PRK11611
431946007753	aminopeptidase B; Provisional; Region: PRK05015
431946007754	Peptidase; Region: DUF3663; pfam12404
431946007755	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
431946007756	interface (dimer of trimers) [polypeptide binding]; other site
431946007757	Substrate-binding/catalytic site; other site
431946007758	Zn-binding sites [ion binding]; other site
431946007759	hypothetical protein; Provisional; Region: PRK10721
431946007760	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
431946007761	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
431946007762	catalytic loop [active]
431946007763	iron binding site [ion binding]; other site
431946007764	chaperone protein HscA; Provisional; Region: hscA; PRK05183
431946007765	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
431946007766	nucleotide binding site [chemical binding]; other site
431946007767	putative NEF/HSP70 interaction site [polypeptide binding]; other site
431946007768	SBD interface [polypeptide binding]; other site
431946007769	co-chaperone HscB; Provisional; Region: hscB; PRK05014
431946007770	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
431946007771	HSP70 interaction site [polypeptide binding]; other site
431946007772	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
431946007773	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
431946007774	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
431946007775	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
431946007776	trimerization site [polypeptide binding]; other site
431946007777	active site
431946007778	cysteine desulfurase; Provisional; Region: PRK14012
431946007779	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
431946007780	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
431946007781	catalytic residue [active]
431946007782	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
431946007783	Rrf2 family protein; Region: rrf2_super; TIGR00738
431946007784	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
431946007785	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
431946007786	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
431946007787	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
431946007788	active site
431946007789	dimerization interface [polypeptide binding]; other site
431946007790	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
431946007791	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
431946007792	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
431946007793	PRD domain; Region: PRD; pfam00874
431946007794	PRD domain; Region: PRD; pfam00874
431946007795	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
431946007796	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946007797	putative substrate translocation pore; other site
431946007798	Predicted membrane protein [Function unknown]; Region: COG2259
431946007799	aldose 1-epimerase, similar to Escherichia coli YphB; Region: Aldose_epim_Ec_YphB; cd09021
431946007800	active site
431946007801	catalytic residues [active]
431946007802	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
431946007803	L-threonine dehydrogenase (TDH)-like; Region: THR_DH_like; cd08239
431946007804	putative NAD(P) binding site [chemical binding]; other site
431946007805	catalytic Zn binding site [ion binding]; other site
431946007806	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
431946007807	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
431946007808	TM-ABC transporter signature motif; other site
431946007809	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
431946007810	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
431946007811	Walker A/P-loop; other site
431946007812	ATP binding site [chemical binding]; other site
431946007813	Q-loop/lid; other site
431946007814	ABC transporter signature motif; other site
431946007815	Walker B; other site
431946007816	D-loop; other site
431946007817	H-loop/switch region; other site
431946007818	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
431946007819	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
431946007820	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
431946007821	ligand binding site [chemical binding]; other site
431946007822	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
431946007823	TPR motif; other site
431946007824	binding surface
431946007825	TPR repeat; Region: TPR_11; pfam13414
431946007826	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
431946007827	TPR motif; other site
431946007828	binding surface
431946007829	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
431946007830	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
431946007831	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
431946007832	nucleotide binding site [chemical binding]; other site
431946007833	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
431946007834	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
431946007835	dimer interface [polypeptide binding]; other site
431946007836	active site
431946007837	glycine-pyridoxal phosphate binding site [chemical binding]; other site
431946007838	folate binding site [chemical binding]; other site
431946007839	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
431946007840	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
431946007841	heme-binding site [chemical binding]; other site
431946007842	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
431946007843	FAD binding pocket [chemical binding]; other site
431946007844	FAD binding motif [chemical binding]; other site
431946007845	phosphate binding motif [ion binding]; other site
431946007846	beta-alpha-beta structure motif; other site
431946007847	NAD binding pocket [chemical binding]; other site
431946007848	Heme binding  pocket [chemical binding]; other site
431946007849	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
431946007850	Nitrogen regulatory protein P-II; Region: P-II; smart00938
431946007851	response regulator GlrR; Provisional; Region: PRK15115
431946007852	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946007853	active site
431946007854	phosphorylation site [posttranslational modification]
431946007855	intermolecular recognition site; other site
431946007856	dimerization interface [polypeptide binding]; other site
431946007857	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946007858	Walker A motif; other site
431946007859	ATP binding site [chemical binding]; other site
431946007860	Walker B motif; other site
431946007861	arginine finger; other site
431946007862	hypothetical protein; Provisional; Region: PRK10722
431946007863	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
431946007864	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
431946007865	dimer interface [polypeptide binding]; other site
431946007866	phosphorylation site [posttranslational modification]
431946007867	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946007868	ATP binding site [chemical binding]; other site
431946007869	Mg2+ binding site [ion binding]; other site
431946007870	G-X-G motif; other site
431946007871	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
431946007872	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
431946007873	dimerization interface [polypeptide binding]; other site
431946007874	ATP binding site [chemical binding]; other site
431946007875	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
431946007876	dimerization interface [polypeptide binding]; other site
431946007877	ATP binding site [chemical binding]; other site
431946007878	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
431946007879	putative active site [active]
431946007880	catalytic triad [active]
431946007881	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
431946007882	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
431946007883	substrate binding pocket [chemical binding]; other site
431946007884	membrane-bound complex binding site; other site
431946007885	hinge residues; other site
431946007886	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
431946007887	N-acetyl-D-glucosamine binding site [chemical binding]; other site
431946007888	catalytic residue [active]
431946007889	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
431946007890	nucleoside/Zn binding site; other site
431946007891	dimer interface [polypeptide binding]; other site
431946007892	catalytic motif [active]
431946007893	hypothetical protein; Provisional; Region: PRK11590
431946007894	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
431946007895	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
431946007896	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
431946007897	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
431946007898	putative active site [active]
431946007899	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
431946007900	holo-[acyl-carrier-protein] synthase; Region: acpS; TIGR00516
431946007901	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
431946007902	active site
431946007903	hydrophilic channel; other site
431946007904	dimerization interface [polypeptide binding]; other site
431946007905	catalytic residues [active]
431946007906	active site lid [active]
431946007907	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
431946007908	Recombination protein O N terminal; Region: RecO_N; pfam11967
431946007909	Recombination protein O C terminal; Region: RecO_C; pfam02565
431946007910	GTPase Era; Reviewed; Region: era; PRK00089
431946007911	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
431946007912	G1 box; other site
431946007913	GTP/Mg2+ binding site [chemical binding]; other site
431946007914	Switch I region; other site
431946007915	G2 box; other site
431946007916	Switch II region; other site
431946007917	G3 box; other site
431946007918	G4 box; other site
431946007919	G5 box; other site
431946007920	KH domain; Region: KH_2; pfam07650
431946007921	ribonuclease III; Reviewed; Region: rnc; PRK00102
431946007922	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
431946007923	dimerization interface [polypeptide binding]; other site
431946007924	active site
431946007925	metal binding site [ion binding]; metal-binding site
431946007926	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
431946007927	dsRNA binding site [nucleotide binding]; other site
431946007928	signal peptidase I; Provisional; Region: PRK10861
431946007929	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
431946007930	Catalytic site [active]
431946007931	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
431946007932	GTP-binding protein LepA; Provisional; Region: PRK05433
431946007933	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
431946007934	G1 box; other site
431946007935	putative GEF interaction site [polypeptide binding]; other site
431946007936	GTP/Mg2+ binding site [chemical binding]; other site
431946007937	Switch I region; other site
431946007938	G2 box; other site
431946007939	G3 box; other site
431946007940	Switch II region; other site
431946007941	G4 box; other site
431946007942	G5 box; other site
431946007943	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
431946007944	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
431946007945	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
431946007946	SoxR reducing system protein RseC; Provisional; Region: PRK10862
431946007947	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
431946007948	anti-sigma E factor; Provisional; Region: rseB; PRK09455
431946007949	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
431946007950	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
431946007951	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
431946007952	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
431946007953	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
431946007954	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
431946007955	DNA binding residues [nucleotide binding]
431946007956	L-aspartate oxidase; Provisional; Region: PRK09077
431946007957	L-aspartate oxidase; Provisional; Region: PRK06175
431946007958	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
431946007959	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
431946007960	Methyltransferase domain; Region: Methyltransf_26; pfam13659
431946007961	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
431946007962	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
431946007963	ATP binding site [chemical binding]; other site
431946007964	Mg++ binding site [ion binding]; other site
431946007965	motif III; other site
431946007966	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
431946007967	nucleotide binding region [chemical binding]; other site
431946007968	ATP-binding site [chemical binding]; other site
431946007969	Transcriptional regulator [Transcription]; Region: LysR; COG0583
431946007970	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946007971	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
431946007972	dimerization interface [polypeptide binding]; other site
431946007973	cysteine/O-acetylserine exporter; Provisional; Region: PRK10323
431946007974	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
431946007975	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
431946007976	ligand binding site [chemical binding]; other site
431946007977	active site
431946007978	UGI interface [polypeptide binding]; other site
431946007979	catalytic site [active]
431946007980	putative methyltransferase; Provisional; Region: PRK10864
431946007981	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
431946007982	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
431946007983	thioredoxin 2; Provisional; Region: PRK10996
431946007984	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
431946007985	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
431946007986	catalytic residues [active]
431946007987	Uncharacterized conserved protein [Function unknown]; Region: COG3148
431946007988	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
431946007989	CoA binding domain; Region: CoA_binding_2; pfam13380
431946007990	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
431946007991	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
431946007992	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
431946007993	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
431946007994	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
431946007995	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
431946007996	domain interface [polypeptide binding]; other site
431946007997	putative active site [active]
431946007998	catalytic site [active]
431946007999	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
431946008000	domain interface [polypeptide binding]; other site
431946008001	putative active site [active]
431946008002	catalytic site [active]
431946008003	lipoprotein; Provisional; Region: PRK10759
431946008004	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
431946008005	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
431946008006	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
431946008007	DNA binding residues [nucleotide binding]
431946008008	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
431946008009	Integrase core domain; Region: rve; pfam00665
431946008010	DNA replication protein [DNA replication, recombination, and repair]; Region: DnaC; COG1484
431946008011	IstB-like ATP binding N-terminal; Region: IstB_IS21_ATP; pfam08483
431946008012	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946008013	Walker A motif; other site
431946008014	ATP binding site [chemical binding]; other site
431946008015	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946008016	putative substrate translocation pore; other site
431946008017	protein disaggregation chaperone; Provisional; Region: PRK10865
431946008018	Clp amino terminal domain; Region: Clp_N; pfam02861
431946008019	Clp amino terminal domain; Region: Clp_N; pfam02861
431946008020	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946008021	Walker A motif; other site
431946008022	ATP binding site [chemical binding]; other site
431946008023	Walker B motif; other site
431946008024	arginine finger; other site
431946008025	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946008026	Walker A motif; other site
431946008027	ATP binding site [chemical binding]; other site
431946008028	Walker B motif; other site
431946008029	arginine finger; other site
431946008030	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
431946008031	hypothetical protein; Provisional; Region: PRK10723
431946008032	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
431946008033	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
431946008034	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
431946008035	RNA binding surface [nucleotide binding]; other site
431946008036	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
431946008037	active site
431946008038	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
431946008039	Protein of unknown function (DUF3897); Region: DUF3897; cl17494
431946008040	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
431946008041	30S subunit binding site; other site
431946008042	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
431946008043	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
431946008044	Prephenate dehydratase; Region: PDT; pfam00800
431946008045	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
431946008046	putative L-Phe binding site [chemical binding]; other site
431946008047	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
431946008048	chorismate mutase domain of T-protein; Region: CM_T; TIGR01799
431946008049	prephenate dehydrogenase; Validated; Region: PRK08507
431946008050	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
431946008051	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
431946008052	lipoprotein; Provisional; Region: PRK11443
431946008053	Protein of unknown function (DUF2799); Region: DUF2799; pfam10973
431946008054	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
431946008055	putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966
431946008056	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
431946008057	metal binding site [ion binding]; metal-binding site
431946008058	active site
431946008059	I-site; other site
431946008060	putative outer membrane lipoprotein; Provisional; Region: PRK09967
431946008061	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
431946008062	ligand binding site [chemical binding]; other site
431946008063	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
431946008064	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
431946008065	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
431946008066	RimM N-terminal domain; Region: RimM; pfam01782
431946008067	PRC-barrel domain; Region: PRC; pfam05239
431946008068	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
431946008069	signal recognition particle protein; Provisional; Region: PRK10867
431946008070	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
431946008071	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
431946008072	P loop; other site
431946008073	GTP binding site [chemical binding]; other site
431946008074	Signal peptide binding domain; Region: SRP_SPB; pfam02978
431946008075	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
431946008076	hypothetical protein; Provisional; Region: PRK11573
431946008077	Domain of unknown function DUF21; Region: DUF21; pfam01595
431946008078	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
431946008079	Transporter associated domain; Region: CorC_HlyC; smart01091
431946008080	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
431946008081	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
431946008082	dimer interface [polypeptide binding]; other site
431946008083	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
431946008084	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
431946008085	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
431946008086	recombination and repair protein; Provisional; Region: PRK10869
431946008087	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
431946008088	Walker A/P-loop; other site
431946008089	ATP binding site [chemical binding]; other site
431946008090	Q-loop/lid; other site
431946008091	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
431946008092	Q-loop/lid; other site
431946008093	ABC transporter signature motif; other site
431946008094	Walker B; other site
431946008095	D-loop; other site
431946008096	H-loop/switch region; other site
431946008097	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
431946008098	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
431946008099	hypothetical protein; Validated; Region: PRK01777
431946008100	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
431946008101	putative coenzyme Q binding site [chemical binding]; other site
431946008102	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
431946008103	SmpB-tmRNA interface; other site
431946008104	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cd00250
431946008105	substrate binding pocket [chemical binding]; other site
431946008106	active site
431946008107	iron coordination sites [ion binding]; other site
431946008108	Predicted dehydrogenase [General function prediction only]; Region: COG0579
431946008109	hydroxyglutarate oxidase; Provisional; Region: PRK11728
431946008110	succinate-semialdehyde dehydrogenase I; Provisional; Region: gabD; PRK11241
431946008111	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
431946008112	tetramerization interface [polypeptide binding]; other site
431946008113	NAD(P) binding site [chemical binding]; other site
431946008114	catalytic residues [active]
431946008115	4-aminobutyrate aminotransferase; Validated; Region: PRK08088
431946008116	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
431946008117	inhibitor-cofactor binding pocket; inhibition site
431946008118	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946008119	catalytic residue [active]
431946008120	gamma-aminobutyrate transporter; Provisional; Region: PRK10197
431946008121	DNA-binding transcriptional regulator CsiR; Provisional; Region: PRK11534
431946008122	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
431946008123	DNA-binding site [nucleotide binding]; DNA binding site
431946008124	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
431946008125	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
431946008126	bacterial OsmY and nodulation domain; Region: BON; smart00749
431946008127	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
431946008128	Uncharacterized homolog of Blt101 [Function unknown]; Region: COG0401
431946008129	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
431946008130	dimerization interface [polypeptide binding]; other site
431946008131	putative DNA binding site [nucleotide binding]; other site
431946008132	Transcriptional regulators [Transcription]; Region: MarR; COG1846
431946008133	putative Zn2+ binding site [ion binding]; other site
431946008134	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YgaP, and similar uncharacterized putative rhodanese-related sulfurtransferases; Region: RHOD_YgaP; cd01527
431946008135	active site residue [active]
431946008136	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
431946008137	DNA binding protein, nucleoid-associated; Provisional; Region: PRK10328
431946008138	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
431946008139	Protein of unknown function (DUF1144); Region: DUF1144; pfam06610
431946008140	hypothetical protein; Provisional; Region: PRK10556
431946008141	hypothetical protein; Provisional; Region: PRK10132
431946008142	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
431946008143	catalytic residues [active]
431946008144	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
431946008145	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
431946008146	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
431946008147	Class I ribonucleotide reductase; Region: RNR_I; cd01679
431946008148	active site
431946008149	dimer interface [polypeptide binding]; other site
431946008150	catalytic residues [active]
431946008151	effector binding site; other site
431946008152	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
431946008153	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
431946008154	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
431946008155	dimer interface [polypeptide binding]; other site
431946008156	putative radical transfer pathway; other site
431946008157	diiron center [ion binding]; other site
431946008158	tyrosyl radical; other site
431946008159	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
431946008160	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
431946008161	Walker A/P-loop; other site
431946008162	ATP binding site [chemical binding]; other site
431946008163	Q-loop/lid; other site
431946008164	ABC transporter signature motif; other site
431946008165	Walker B; other site
431946008166	D-loop; other site
431946008167	H-loop/switch region; other site
431946008168	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
431946008169	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
431946008170	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946008171	dimer interface [polypeptide binding]; other site
431946008172	conserved gate region; other site
431946008173	putative PBP binding loops; other site
431946008174	ABC-ATPase subunit interface; other site
431946008175	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
431946008176	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
431946008177	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
431946008178	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946008179	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
431946008180	putative L-valine exporter; Provisional; Region: PRK10408
431946008181	transcriptional repressor MprA; Provisional; Region: PRK10870
431946008182	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
431946008183	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
431946008184	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
431946008185	HlyD family secretion protein; Region: HlyD_3; pfam13437
431946008186	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
431946008187	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946008188	putative substrate translocation pore; other site
431946008189	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946008190	RNA ligase; Region: RNA_ligase; pfam09414
431946008191	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
431946008192	Zn2+ binding site [ion binding]; other site
431946008193	Mg2+ binding site [ion binding]; other site
431946008194	AAA domain; Region: AAA_33; pfam13671
431946008195	S-ribosylhomocysteinase; Provisional; Region: PRK02260
431946008196	glutamate--cysteine ligase; Provisional; Region: PRK02107
431946008197	Predicted membrane protein [Function unknown]; Region: COG1238
431946008198	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
431946008199	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
431946008200	motif II; other site
431946008201	carbon storage regulator; Provisional; Region: PRK01712
431946008202	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
431946008203	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
431946008204	motif 1; other site
431946008205	active site
431946008206	motif 2; other site
431946008207	motif 3; other site
431946008208	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
431946008209	DHHA1 domain; Region: DHHA1; pfam02272
431946008210	recombination regulator RecX; Reviewed; Region: recX; PRK00117
431946008211	recombinase A; Provisional; Region: recA; PRK09354
431946008212	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
431946008213	hexamer interface [polypeptide binding]; other site
431946008214	Walker A motif; other site
431946008215	ATP binding site [chemical binding]; other site
431946008216	Walker B motif; other site
431946008217	hypothetical protein; Validated; Region: PRK03661
431946008218	Transglycosylase SLT domain; Region: SLT_2; pfam13406
431946008219	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
431946008220	N-acetyl-D-glucosamine binding site [chemical binding]; other site
431946008221	PTS system, glucitol/sorbitol-specific, IIC component; Region: EII-GUT; TIGR00821
431946008222	PTS system, glucitol/sorbitol-specific, IIBC component; Region: EIIBC-GUT; TIGR00825
431946008223	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
431946008224	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
431946008225	PTS system glucitol/sorbitol-specific transporter subunit IIA; Provisional; Region: PRK10377
431946008226	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
431946008227	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
431946008228	putative NAD(P) binding site [chemical binding]; other site
431946008229	active site
431946008230	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
431946008231	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
431946008232	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
431946008233	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
431946008234	D-arabinose 5-phosphate isomerase; Provisional; Region: gutQ; PRK11543
431946008235	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
431946008236	putative active site [active]
431946008237	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
431946008238	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
431946008239	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
431946008240	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946008241	Walker A motif; other site
431946008242	ATP binding site [chemical binding]; other site
431946008243	Walker B motif; other site
431946008244	arginine finger; other site
431946008245	anaerobic nitric oxide reductase flavorubredoxin; Provisional; Region: PRK05452
431946008246	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
431946008247	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
431946008248	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
431946008249	iron binding site [ion binding]; other site
431946008250	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
431946008251	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
431946008252	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
431946008253	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
431946008254	Acylphosphatase; Region: Acylphosphatase; pfam00708
431946008255	HypF finger; Region: zf-HYPF; pfam07503
431946008256	HypF finger; Region: zf-HYPF; pfam07503
431946008257	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
431946008258	formate dehydrogenase-H ferredoxin subunit; Provisional; Region: PRK10330
431946008259	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
431946008260	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
431946008261	non-specific DNA binding site [nucleotide binding]; other site
431946008262	salt bridge; other site
431946008263	sequence-specific DNA binding site [nucleotide binding]; other site
431946008264	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
431946008265	nickel binding site [ion binding]; other site
431946008266	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
431946008267	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
431946008268	formate hydrogenlyase complex iron-sulfur subunit; Provisional; Region: PRK12387
431946008269	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
431946008270	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
431946008271	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
431946008272	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
431946008273	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
431946008274	NADH dehydrogenase; Region: NADHdh; cl00469
431946008275	formate hydrogenlyase subunit 3; Reviewed; Region: PRK08042
431946008276	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
431946008277	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
431946008278	formate hydrogenlyase regulatory protein HycA; Provisional; Region: PRK10198
431946008279	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
431946008280	hydrogenase nickel incorporation protein; Validated; Region: hypA; PRK03681
431946008281	hydrogenase nickel incorporation protein HypB; Provisional; Region: PRK10463
431946008282	hydrogenase assembly chaperone; Provisional; Region: PRK10409
431946008283	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
431946008284	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
431946008285	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
431946008286	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
431946008287	dimerization interface [polypeptide binding]; other site
431946008288	ATP binding site [chemical binding]; other site
431946008289	formate hydrogenlyase transcriptional activator FhlA; Provisional; Region: PRK15429
431946008290	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
431946008291	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
431946008292	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946008293	Walker A motif; other site
431946008294	ATP binding site [chemical binding]; other site
431946008295	Walker B motif; other site
431946008296	arginine finger; other site
431946008297	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
431946008298	molybdenum-pterin binding domain; Region: Mop; TIGR00638
431946008299	Molybdopterin-binding protein [Coenzyme metabolism]; Region: MopI; COG3585
431946008300	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
431946008301	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
431946008302	MutS domain I; Region: MutS_I; pfam01624
431946008303	MutS domain II; Region: MutS_II; pfam05188
431946008304	MutS domain III; Region: MutS_III; pfam05192
431946008305	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
431946008306	Walker A/P-loop; other site
431946008307	ATP binding site [chemical binding]; other site
431946008308	Q-loop/lid; other site
431946008309	ABC transporter signature motif; other site
431946008310	Walker B; other site
431946008311	D-loop; other site
431946008312	H-loop/switch region; other site
431946008313	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
431946008314	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
431946008315	active site
431946008316	metal binding site [ion binding]; metal-binding site
431946008317	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
431946008318	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
431946008319	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
431946008320	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
431946008321	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
431946008322	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
431946008323	putative aldolase; Validated; Region: PRK08130
431946008324	active site
431946008325	intersubunit interface [polypeptide binding]; other site
431946008326	Zn2+ binding site [ion binding]; other site
431946008327	hypothetical protein; Provisional; Region: PRK09989
431946008328	putative transporter; Provisional; Region: PRK09821
431946008329	GntP family permease; Region: GntP_permease; pfam02447
431946008330	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
431946008331	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
431946008332	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
431946008333	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
431946008334	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
431946008335	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
431946008336	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
431946008337	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
431946008338	DNA binding residues [nucleotide binding]
431946008339	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
431946008340	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
431946008341	Peptidase family M23; Region: Peptidase_M23; pfam01551
431946008342	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
431946008343	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946008344	S-adenosylmethionine binding site [chemical binding]; other site
431946008345	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
431946008346	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
431946008347	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
431946008348	Permutation of conserved domain; other site
431946008349	active site
431946008350	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
431946008351	homotrimer interaction site [polypeptide binding]; other site
431946008352	zinc binding site [ion binding]; other site
431946008353	CDP-binding sites; other site
431946008354	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
431946008355	substrate binding site; other site
431946008356	dimer interface; other site
431946008357	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
431946008358	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
431946008359	Protein of unknown function (DUF3561); Region: DUF3561; pfam12084
431946008360	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
431946008361	ligand-binding site [chemical binding]; other site
431946008362	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
431946008363	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
431946008364	CysD dimerization site [polypeptide binding]; other site
431946008365	G1 box; other site
431946008366	putative GEF interaction site [polypeptide binding]; other site
431946008367	GTP/Mg2+ binding site [chemical binding]; other site
431946008368	Switch I region; other site
431946008369	G2 box; other site
431946008370	G3 box; other site
431946008371	Switch II region; other site
431946008372	G4 box; other site
431946008373	G5 box; other site
431946008374	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
431946008375	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
431946008376	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
431946008377	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
431946008378	Active Sites [active]
431946008379	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
431946008380	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
431946008381	metal binding site [ion binding]; metal-binding site
431946008382	Hok/gef family; Region: HOK_GEF; pfam01848
431946008383	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
431946008384	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
431946008385	Active Sites [active]
431946008386	sulfite reductase subunit beta; Provisional; Region: PRK13504
431946008387	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
431946008388	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
431946008389	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
431946008390	Flavodoxin; Region: Flavodoxin_1; pfam00258
431946008391	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
431946008392	FAD binding pocket [chemical binding]; other site
431946008393	FAD binding motif [chemical binding]; other site
431946008394	catalytic residues [active]
431946008395	NAD binding pocket [chemical binding]; other site
431946008396	phosphate binding motif [ion binding]; other site
431946008397	beta-alpha-beta structure motif; other site
431946008398	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
431946008399	active site
431946008400	putative oxidoreductase FixC; Provisional; Region: PRK10157
431946008401	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
431946008402	Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription]; Region: GlpP; COG1954
431946008403	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
431946008404	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
431946008405	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
431946008406	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
431946008407	Ligand binding site [chemical binding]; other site
431946008408	Electron transfer flavoprotein domain; Region: ETF; pfam01012
431946008409	benzoate transport; Region: 2A0115; TIGR00895
431946008410	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946008411	putative substrate translocation pore; other site
431946008412	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
431946008413	FAD binding domain; Region: FAD_binding_4; pfam01565
431946008414	2-deoxy-D-gluconate 3-dehydrogenase; Provisional; Region: PRK06935
431946008415	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
431946008416	NADP binding site [chemical binding]; other site
431946008417	homodimer interface [polypeptide binding]; other site
431946008418	active site
431946008419	Major Facilitator Superfamily; Region: MFS_1; pfam07690
431946008420	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946008421	putative substrate translocation pore; other site
431946008422	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
431946008423	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
431946008424	nucleotide binding site [chemical binding]; other site
431946008425	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
431946008426	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
431946008427	putative substrate binding site [chemical binding]; other site
431946008428	putative ATP binding site [chemical binding]; other site
431946008429	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
431946008430	trimer interface; other site
431946008431	sugar binding site [chemical binding]; other site
431946008432	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
431946008433	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
431946008434	active site turn [active]
431946008435	phosphorylation site [posttranslational modification]
431946008436	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
431946008437	sucrose-6-phosphate hydrolase; Region: scrB_fam; TIGR01322
431946008438	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
431946008439	substrate binding [chemical binding]; other site
431946008440	active site
431946008441	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
431946008442	D-fructose-responsive transcription factor; Region: fruct_sucro_rep; TIGR02417
431946008443	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
431946008444	DNA binding site [nucleotide binding]
431946008445	domain linker motif; other site
431946008446	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
431946008447	dimerization interface [polypeptide binding]; other site
431946008448	ligand binding site [chemical binding]; other site
431946008449	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
431946008450	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
431946008451	Beta-propeller domains of methanol dehydrogenase type [General function prediction only]; Region: COG1512
431946008452	Repair protein; Region: Repair_PSII; pfam04536
431946008453	enolase; Provisional; Region: eno; PRK00077
431946008454	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
431946008455	dimer interface [polypeptide binding]; other site
431946008456	metal binding site [ion binding]; metal-binding site
431946008457	substrate binding pocket [chemical binding]; other site
431946008458	CTP synthetase; Validated; Region: pyrG; PRK05380
431946008459	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
431946008460	Catalytic site [active]
431946008461	active site
431946008462	UTP binding site [chemical binding]; other site
431946008463	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
431946008464	active site
431946008465	putative oxyanion hole; other site
431946008466	catalytic triad [active]
431946008467	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
431946008468	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
431946008469	homodimer interface [polypeptide binding]; other site
431946008470	metal binding site [ion binding]; metal-binding site
431946008471	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
431946008472	homodimer interface [polypeptide binding]; other site
431946008473	active site
431946008474	putative chemical substrate binding site [chemical binding]; other site
431946008475	metal binding site [ion binding]; metal-binding site
431946008476	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
431946008477	HD domain; Region: HD_4; pfam13328
431946008478	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
431946008479	synthetase active site [active]
431946008480	NTP binding site [chemical binding]; other site
431946008481	metal binding site [ion binding]; metal-binding site
431946008482	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
431946008483	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
431946008484	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
431946008485	TRAM domain; Region: TRAM; pfam01938
431946008486	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946008487	S-adenosylmethionine binding site [chemical binding]; other site
431946008488	hybrid sensory histidine kinase BarA; Provisional; Region: PRK11107
431946008489	Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984
431946008490	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
431946008491	dimerization interface [polypeptide binding]; other site
431946008492	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
431946008493	dimer interface [polypeptide binding]; other site
431946008494	phosphorylation site [posttranslational modification]
431946008495	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946008496	ATP binding site [chemical binding]; other site
431946008497	Mg2+ binding site [ion binding]; other site
431946008498	G-X-G motif; other site
431946008499	Uncharacterized domain of BarA-like signal transduction histidine kinases [Signal transduction mechanisms]; Region: COG4999
431946008500	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946008501	active site
431946008502	phosphorylation site [posttranslational modification]
431946008503	intermolecular recognition site; other site
431946008504	dimerization interface [polypeptide binding]; other site
431946008505	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
431946008506	putative binding surface; other site
431946008507	active site
431946008508	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
431946008509	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
431946008510	active site
431946008511	tetramer interface [polypeptide binding]; other site
431946008512	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
431946008513	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
431946008514	active site
431946008515	tetramer interface [polypeptide binding]; other site
431946008516	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946008517	D-galactonate transporter; Region: 2A0114; TIGR00893
431946008518	putative substrate translocation pore; other site
431946008519	flavodoxin; Provisional; Region: PRK08105
431946008520	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
431946008521	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
431946008522	probable active site [active]
431946008523	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3098
431946008524	SecY interacting protein Syd; Provisional; Region: PRK04968
431946008525	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
431946008526	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
431946008527	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
431946008528	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
431946008529	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
431946008530	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
431946008531	serine transporter; Region: stp; TIGR00814
431946008532	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
431946008533	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
431946008534	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
431946008535	flap endonuclease-like protein; Provisional; Region: PRK09482
431946008536	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
431946008537	active site
431946008538	metal binding site 1 [ion binding]; metal-binding site
431946008539	putative 5' ssDNA interaction site; other site
431946008540	metal binding site 3; metal-binding site
431946008541	metal binding site 2 [ion binding]; metal-binding site
431946008542	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
431946008543	putative DNA binding site [nucleotide binding]; other site
431946008544	putative metal binding site [ion binding]; other site
431946008545	L-1,2-propanediol oxidoreductase; Provisional; Region: PRK10624
431946008546	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
431946008547	dimer interface [polypeptide binding]; other site
431946008548	active site
431946008549	metal binding site [ion binding]; metal-binding site
431946008550	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
431946008551	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
431946008552	intersubunit interface [polypeptide binding]; other site
431946008553	active site
431946008554	Zn2+ binding site [ion binding]; other site
431946008555	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
431946008556	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946008557	putative substrate translocation pore; other site
431946008558	L-fucose isomerase; Provisional; Region: fucI; PRK10991
431946008559	L-fucose isomerase (FucIase); FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose during glycolysis). L-fucose (or 6-deoxy-L-galactose) is found in blood group...; Region: L-fucose_isomerase; cd03556
431946008560	hexamer (dimer of trimers) interface [polypeptide binding]; other site
431946008561	trimer interface [polypeptide binding]; other site
431946008562	substrate binding site [chemical binding]; other site
431946008563	Mn binding site [ion binding]; other site
431946008564	L-fuculokinase; Provisional; Region: PRK10331
431946008565	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
431946008566	nucleotide binding site [chemical binding]; other site
431946008567	L-fucose mutarotase; Provisional; Region: fucU; PRK15420
431946008568	DNA-binding transcriptional activator FucR; Provisional; Region: PRK10411
431946008569	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
431946008570	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
431946008571	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
431946008572	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
431946008573	hypothetical protein; Provisional; Region: PRK10873
431946008574	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
431946008575	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946008576	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
431946008577	dimerization interface [polypeptide binding]; other site
431946008578	substrate binding pocket [chemical binding]; other site
431946008579	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
431946008580	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
431946008581	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
431946008582	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
431946008583	catalytic residue [active]
431946008584	CsdA-binding activator; Provisional; Region: PRK15019
431946008585	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
431946008586	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
431946008587	putative ATP binding site [chemical binding]; other site
431946008588	putative substrate interface [chemical binding]; other site
431946008589	murein transglycosylase A; Provisional; Region: mltA; PRK11162
431946008590	MltA specific insert domain; Region: MltA; pfam03562
431946008591	3D domain; Region: 3D; pfam06725
431946008592	Protein of unknown function (DUF770); Region: DUF770; pfam05591
431946008593	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517; cl05484
431946008594	Protein of unknown function (DUF877); Region: DUF877; pfam05943
431946008595	type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353
431946008596	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
431946008597	Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; pfam09850
431946008598	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
431946008599	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
431946008600	ligand binding site [chemical binding]; other site
431946008601	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
431946008602	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
431946008603	Clp amino terminal domain; Region: Clp_N; pfam02861
431946008604	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946008605	Walker A motif; other site
431946008606	ATP binding site [chemical binding]; other site
431946008607	Walker B motif; other site
431946008608	arginine finger; other site
431946008609	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946008610	Walker A motif; other site
431946008611	ATP binding site [chemical binding]; other site
431946008612	Walker B motif; other site
431946008613	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
431946008614	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
431946008615	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
431946008616	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
431946008617	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
431946008618	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4253
431946008619	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
431946008620	N-acetyl-D-glucosamine binding site [chemical binding]; other site
431946008621	catalytic residue [active]
431946008622	DNA replication protein [DNA replication, recombination, and repair]; Region: DnaC; COG1484
431946008623	IstB-like ATP binding N-terminal; Region: IstB_IS21_ATP; pfam08483
431946008624	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946008625	Walker A motif; other site
431946008626	ATP binding site [chemical binding]; other site
431946008627	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
431946008628	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
431946008629	DNA binding residues [nucleotide binding]
431946008630	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
431946008631	Integrase core domain; Region: rve; pfam00665
431946008632	Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and    vesicular transport]; Region: IcmF; COG3523
431946008633	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
431946008634	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
431946008635	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
431946008636	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
431946008637	type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362
431946008638	PAAR motif; Region: PAAR_motif; pfam05488
431946008639	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
431946008640	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
431946008641	Protein of unknown function (DUF1305); Region: DUF1305; pfam06996
431946008642	Type VI secretion lipoprotein; Region: T6SS-SciN; pfam12790
431946008643	type VI secretion system lysozyme-like protein; Region: VI_zyme; TIGR03357
431946008644	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
431946008645	ImpA domain protein; Region: DUF3702; pfam12486
431946008646	Putative D-3-Phosphoglycerate Dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_like_2; cd12172
431946008647	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
431946008648	putative ligand binding site [chemical binding]; other site
431946008649	putative NAD binding site [chemical binding]; other site
431946008650	catalytic site [active]
431946008651	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
431946008652	putative active site [active]
431946008653	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
431946008654	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
431946008655	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946008656	homodimer interface [polypeptide binding]; other site
431946008657	catalytic residue [active]
431946008658	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
431946008659	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
431946008660	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
431946008661	active site turn [active]
431946008662	phosphorylation site [posttranslational modification]
431946008663	CAT RNA binding domain; Region: CAT_RBD; pfam03123
431946008664	PRD domain; Region: PRD; pfam00874
431946008665	PRD domain; Region: PRD; pfam00874
431946008666	AMIN domain; Region: AMIN; pfam11741
431946008667	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
431946008668	active site
431946008669	metal binding site [ion binding]; metal-binding site
431946008670	N-acetylglutamate synthase; Validated; Region: PRK05279
431946008671	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
431946008672	putative feedback inhibition sensing region; other site
431946008673	putative nucleotide binding site [chemical binding]; other site
431946008674	putative substrate binding site [chemical binding]; other site
431946008675	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
431946008676	Coenzyme A binding pocket [chemical binding]; other site
431946008677	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
431946008678	AAA domain; Region: AAA_30; pfam13604
431946008679	Family description; Region: UvrD_C_2; pfam13538
431946008680	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
431946008681	protease3; Provisional; Region: PRK15101
431946008682	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
431946008683	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
431946008684	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
431946008685	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
431946008686	exodeoxyribonuclease V, gamma subunit; Region: recC; TIGR01450
431946008687	hypothetical protein; Provisional; Region: PRK10332
431946008688	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
431946008689	hypothetical protein; Provisional; Region: PRK11521
431946008690	hypothetical protein; Provisional; Region: PRK10557
431946008691	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
431946008692	hypothetical protein; Provisional; Region: PRK10506
431946008693	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
431946008694	thymidylate synthase; Reviewed; Region: thyA; PRK01827
431946008695	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
431946008696	dimerization interface [polypeptide binding]; other site
431946008697	active site
431946008698	prolipoprotein diacylglyceryl transferase; Region: lgt; TIGR00544
431946008699	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
431946008700	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
431946008701	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
431946008702	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
431946008703	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
431946008704	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
431946008705	putative active site [active]
431946008706	Ap4A binding site [chemical binding]; other site
431946008707	nudix motif; other site
431946008708	putative metal binding site [ion binding]; other site
431946008709	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
431946008710	putative DNA-binding cleft [nucleotide binding]; other site
431946008711	putative DNA clevage site; other site
431946008712	molecular lever; other site
431946008713	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
431946008714	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
431946008715	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
431946008716	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
431946008717	active site
431946008718	catalytic tetrad [active]
431946008719	lysophospholipid transporter LplT; Provisional; Region: PRK11195
431946008720	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946008721	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
431946008722	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
431946008723	putative acyl-acceptor binding pocket; other site
431946008724	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
431946008725	acyl-activating enzyme (AAE) consensus motif; other site
431946008726	putative AMP binding site [chemical binding]; other site
431946008727	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
431946008728	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
431946008729	DNA binding site [nucleotide binding]
431946008730	domain linker motif; other site
431946008731	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
431946008732	dimerization interface (closed form) [polypeptide binding]; other site
431946008733	ligand binding site [chemical binding]; other site
431946008734	diaminopimelate decarboxylase; Provisional; Region: PRK11165
431946008735	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
431946008736	active site
431946008737	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
431946008738	substrate binding site [chemical binding]; other site
431946008739	catalytic residues [active]
431946008740	dimer interface [polypeptide binding]; other site
431946008741	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
431946008742	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946008743	The C-terminal substrate binding domain of LysR, transcriptional regulator for lysine biosynthesis, contains the type 2 periplasmic binding fold; Region: PBP2_LysR; cd08456
431946008744	putative dimerization interface [polypeptide binding]; other site
431946008745	putative racemase; Provisional; Region: PRK10200
431946008746	aspartate racemase; Region: asp_race; TIGR00035
431946008747	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
431946008748	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946008749	putative substrate translocation pore; other site
431946008750	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946008751	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
431946008752	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
431946008753	NADP binding site [chemical binding]; other site
431946008754	homodimer interface [polypeptide binding]; other site
431946008755	active site
431946008756	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
431946008757	putative acyltransferase; Provisional; Region: PRK05790
431946008758	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
431946008759	dimer interface [polypeptide binding]; other site
431946008760	active site
431946008761	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
431946008762	serine transporter; Region: stp; TIGR00814
431946008763	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
431946008764	Peptidase family M23; Region: Peptidase_M23; pfam01551
431946008765	xanthine dehydrogenase subunit XdhA; Provisional; Region: PRK09970
431946008766	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
431946008767	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
431946008768	xanthine dehydrogenase subunit XdhB; Provisional; Region: PRK09971
431946008769	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
431946008770	xanthine dehydrogenase subunit XdhC; Provisional; Region: PRK09908
431946008771	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
431946008772	catalytic loop [active]
431946008773	iron binding site [ion binding]; other site
431946008774	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
431946008775	GAF domain; Region: GAF; cl17456
431946008776	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
431946008777	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
431946008778	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946008779	Walker A motif; other site
431946008780	ATP binding site [chemical binding]; other site
431946008781	Walker B motif; other site
431946008782	arginine finger; other site
431946008783	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
431946008784	aspartate/ornithine carbamoyltransferase family protein; Validated; Region: PRK07200
431946008785	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
431946008786	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
431946008787	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
431946008788	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cd00640
431946008789	catalytic residue [active]
431946008790	peptidase; Reviewed; Region: PRK13004
431946008791	M20 Peptidases with similarity to acetylornithine deacetylases and succinyl-diaminopimelate desuccinylases; Region: M20_ArgE_DapE_like4; cd05649
431946008792	putative metal binding site [ion binding]; other site
431946008793	putative dimer interface [polypeptide binding]; other site
431946008794	D-hydantoinase; Region: D-hydantoinase; TIGR02033
431946008795	D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine...; Region: D-HYD; cd01314
431946008796	tetramer interface [polypeptide binding]; other site
431946008797	active site
431946008798	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
431946008799	carbamate kinase; Reviewed; Region: PRK12686
431946008800	putative substrate binding site [chemical binding]; other site
431946008801	homodimer interface [polypeptide binding]; other site
431946008802	nucleotide binding site [chemical binding]; other site
431946008803	nucleotide binding site [chemical binding]; other site
431946008804	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
431946008805	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
431946008806	XdhC Rossmann domain; Region: XdhC_C; pfam13478
431946008807	selenium-dependent molybdenum hydroxylase system protein, YqeB family; Region: matur_yqeB; TIGR03309
431946008808	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
431946008809	probable selenium-dependent hydroxylase accessory protein YqeC; Region: TIGR03172
431946008810	GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function; Region: GT_2_like_f; cd04182
431946008811	Ligand binding site; other site
431946008812	metal-binding site
431946008813	putative selenate reductase subunit YgfK; Provisional; Region: PRK09853
431946008814	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
431946008815	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
431946008816	putative selenium metabolism protein SsnA; Region: Se_ssnA; TIGR03314
431946008817	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
431946008818	active site
431946008819	putative substrate binding pocket [chemical binding]; other site
431946008820	probable selenate reductase, FAD-binding subunit; Region: Se_sel_red_FAD; TIGR03312
431946008821	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
431946008822	putative hypoxanthine oxidase; Provisional; Region: PRK09800
431946008823	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
431946008824	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
431946008825	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
431946008826	uracil-xanthine permease; Region: ncs2; TIGR00801
431946008827	guanine deaminase; Provisional; Region: PRK09228
431946008828	Guanine deaminase (GDEase). Guanine deaminase is an aminohydrolase responsible for the conversion of guanine to xanthine and ammonia, the first step to utilize guanine as a nitrogen source. This reaction also removes the guanine base from the pool and...; Region: GDEase; cd01303
431946008829	active site
431946008830	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
431946008831	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
431946008832	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12809
431946008833	4Fe-4S binding domain; Region: Fer4; pfam00037
431946008834	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
431946008835	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
431946008836	xanthine permease; Region: pbuX; TIGR03173
431946008837	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
431946008838	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
431946008839	active site
431946008840	metal binding site [ion binding]; metal-binding site
431946008841	nudix motif; other site
431946008842	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
431946008843	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
431946008844	dimer interface [polypeptide binding]; other site
431946008845	putative anticodon binding site; other site
431946008846	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
431946008847	motif 1; other site
431946008848	active site
431946008849	motif 2; other site
431946008850	motif 3; other site
431946008851	peptide chain release factor 2; Provisional; Region: PRK08787
431946008852	This domain is found in peptide chain release factors; Region: PCRF; smart00937
431946008853	RF-1 domain; Region: RF-1; pfam00472
431946008854	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
431946008855	DHH family; Region: DHH; pfam01368
431946008856	DHHA1 domain; Region: DHHA1; pfam02272
431946008857	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
431946008858	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
431946008859	dimerization domain [polypeptide binding]; other site
431946008860	dimer interface [polypeptide binding]; other site
431946008861	catalytic residues [active]
431946008862	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
431946008863	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
431946008864	active site
431946008865	Int/Topo IB signature motif; other site
431946008866	flavodoxin FldB; Provisional; Region: PRK12359
431946008867	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
431946008868	hypothetical protein; Provisional; Region: PRK10878
431946008869	putative global regulator; Reviewed; Region: PRK09559
431946008870	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
431946008871	hemolysin; Provisional; Region: PRK15087
431946008872	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
431946008873	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
431946008874	6-phospho-beta-glucosidase BglA; Provisional; Region: PRK15014
431946008875	beta-galactosidase; Region: BGL; TIGR03356
431946008876	glycine dehydrogenase; Provisional; Region: PRK05367
431946008877	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
431946008878	tetramer interface [polypeptide binding]; other site
431946008879	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946008880	catalytic residue [active]
431946008881	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
431946008882	tetramer interface [polypeptide binding]; other site
431946008883	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946008884	catalytic residue [active]
431946008885	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
431946008886	lipoyl attachment site [posttranslational modification]; other site
431946008887	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
431946008888	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
431946008889	oxidoreductase; Provisional; Region: PRK08013
431946008890	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
431946008891	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
431946008892	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
431946008893	proline aminopeptidase P II; Provisional; Region: PRK10879
431946008894	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
431946008895	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
431946008896	active site
431946008897	hypothetical protein; Reviewed; Region: PRK01736
431946008898	Z-ring-associated protein; Provisional; Region: PRK10972
431946008899	5-formyltetrahydrofolate cyclo-ligase family protein; Provisional; Region: PRK10333
431946008900	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
431946008901	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
431946008902	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
431946008903	ligand binding site [chemical binding]; other site
431946008904	NAD binding site [chemical binding]; other site
431946008905	tetramer interface [polypeptide binding]; other site
431946008906	catalytic site [active]
431946008907	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
431946008908	L-serine binding site [chemical binding]; other site
431946008909	ACT domain interface; other site
431946008910	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
431946008911	tetramer (dimer of dimers) interface [polypeptide binding]; other site
431946008912	active site
431946008913	dimer interface [polypeptide binding]; other site
431946008914	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
431946008915	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
431946008916	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946008917	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
431946008918	putative dimerization interface [polypeptide binding]; other site
431946008919	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM)-like family; contains proteins similar to MCM, and the large subunit of Streptomyces coenzyme B12-dependent isobutyryl-CoA mutase (ICM). MCM catalyzes the isomerization of...; Region: MM_CoA_mutase; cl00817
431946008920	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
431946008921	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946008922	Transcriptional regulator [Transcription]; Region: LysR; COG0583
431946008923	Uncharacterized conserved protein [Function unknown]; Region: COG2968
431946008924	oxidative stress defense protein; Provisional; Region: PRK11087
431946008925	arginine exporter protein; Provisional; Region: PRK09304
431946008926	mechanosensitive channel MscS; Provisional; Region: PRK10334
431946008927	Mechanosensitive ion channel; Region: MS_channel; pfam00924
431946008928	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
431946008929	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
431946008930	active site
431946008931	intersubunit interface [polypeptide binding]; other site
431946008932	zinc binding site [ion binding]; other site
431946008933	Na+ binding site [ion binding]; other site
431946008934	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
431946008935	Phosphoglycerate kinase; Region: PGK; pfam00162
431946008936	substrate binding site [chemical binding]; other site
431946008937	hinge regions; other site
431946008938	ADP binding site [chemical binding]; other site
431946008939	catalytic site [active]
431946008940	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
431946008941	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
431946008942	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
431946008943	Domain of unknown function found in archaea, bacteria, and plants; Region: DUF296; cd11378
431946008944	trimer interface [polypeptide binding]; other site
431946008945	putative Zn binding site [ion binding]; other site
431946008946	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
431946008947	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
431946008948	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
431946008949	Walker A/P-loop; other site
431946008950	ATP binding site [chemical binding]; other site
431946008951	Q-loop/lid; other site
431946008952	ABC transporter signature motif; other site
431946008953	Walker B; other site
431946008954	D-loop; other site
431946008955	H-loop/switch region; other site
431946008956	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
431946008957	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
431946008958	Walker A/P-loop; other site
431946008959	ATP binding site [chemical binding]; other site
431946008960	Q-loop/lid; other site
431946008961	ABC transporter signature motif; other site
431946008962	Walker B; other site
431946008963	D-loop; other site
431946008964	H-loop/switch region; other site
431946008965	nucleoside triphosphate hydrolase domain-containing protein; Reviewed; Region: PRK09270
431946008966	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
431946008967	active site
431946008968	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
431946008969	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10022
431946008970	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
431946008971	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
431946008972	putative active site [active]
431946008973	L-sorbose-1-phosphate reductase; Region: sorbose_phosphate_red; cd08238
431946008974	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
431946008975	putative NAD(P) binding site [chemical binding]; other site
431946008976	catalytic Zn binding site [ion binding]; other site
431946008977	Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism]; Region: MtlA; COG2213
431946008978	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
431946008979	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
431946008980	active site
431946008981	P-loop; other site
431946008982	phosphorylation site [posttranslational modification]
431946008983	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
431946008984	active site
431946008985	phosphorylation site [posttranslational modification]
431946008986	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
431946008987	SPFH domain / Band 7 family; Region: Band_7; pfam01145
431946008988	transketolase; Reviewed; Region: PRK12753
431946008989	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
431946008990	TPP-binding site [chemical binding]; other site
431946008991	dimer interface [polypeptide binding]; other site
431946008992	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
431946008993	PYR/PP interface [polypeptide binding]; other site
431946008994	dimer interface [polypeptide binding]; other site
431946008995	TPP binding site [chemical binding]; other site
431946008996	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
431946008997	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
431946008998	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
431946008999	agmatinase; Region: agmatinase; TIGR01230
431946009000	oligomer interface [polypeptide binding]; other site
431946009001	putative active site [active]
431946009002	Mn binding site [ion binding]; other site
431946009003	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
431946009004	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
431946009005	dimer interface [polypeptide binding]; other site
431946009006	active site
431946009007	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
431946009008	catalytic residues [active]
431946009009	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
431946009010	Virulence promoting factor; Region: YqgB; pfam11036
431946009011	Protein of unknown function (DUF2684); Region: DUF2684; pfam10885
431946009012	S-adenosylmethionine synthetase; Validated; Region: PRK05250
431946009013	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
431946009014	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
431946009015	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
431946009016	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
431946009017	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946009018	putative substrate translocation pore; other site
431946009019	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946009020	hypothetical protein; Provisional; Region: PRK04860
431946009021	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
431946009022	DNA-specific endonuclease I; Provisional; Region: PRK15137
431946009023	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
431946009024	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
431946009025	RNA methyltransferase, RsmE family; Region: TIGR00046
431946009026	glutathione synthetase; Provisional; Region: PRK05246
431946009027	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
431946009028	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
431946009029	hypothetical protein; Validated; Region: PRK00228
431946009030	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
431946009031	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
431946009032	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
431946009033	Walker A motif; other site
431946009034	ATP binding site [chemical binding]; other site
431946009035	Walker B motif; other site
431946009036	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
431946009037	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
431946009038	catalytic residue [active]
431946009039	YGGT family; Region: YGGT; pfam02325
431946009040	YGGT family; Region: YGGT; pfam02325
431946009041	hypothetical protein; Validated; Region: PRK05090
431946009042	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
431946009043	active site
431946009044	dimerization interface [polypeptide binding]; other site
431946009045	HemN family oxidoreductase; Provisional; Region: PRK05660
431946009046	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
431946009047	FeS/SAM binding site; other site
431946009048	HemN C-terminal domain; Region: HemN_C; pfam06969
431946009049	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
431946009050	tripartite ATP-independent periplasmic transporter solute receptor, DctP family; Region: dctP; TIGR00787
431946009051	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
431946009052	DctM-like transporters; Region: DctM; pfam06808
431946009053	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; COG1593
431946009054	Protein of unknown function (DUF1202); Region: DUF1202; pfam06717
431946009055	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cd00411
431946009056	homodimer interface [polypeptide binding]; other site
431946009057	active site
431946009058	hypothetical protein; Provisional; Region: PRK10626
431946009059	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
431946009060	hypothetical protein; Provisional; Region: PRK11702
431946009061	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
431946009062	adenine DNA glycosylase; Provisional; Region: PRK10880
431946009063	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
431946009064	minor groove reading motif; other site
431946009065	helix-hairpin-helix signature motif; other site
431946009066	substrate binding pocket [chemical binding]; other site
431946009067	active site
431946009068	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576
431946009069	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
431946009070	DNA binding and oxoG recognition site [nucleotide binding]
431946009071	oxidative damage protection protein; Provisional; Region: PRK05408
431946009072	murein transglycosylase C; Provisional; Region: mltC; PRK11671
431946009073	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
431946009074	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
431946009075	N-acetyl-D-glucosamine binding site [chemical binding]; other site
431946009076	catalytic residue [active]
431946009077	nucleoside transporter; Region: 2A0110; TIGR00889
431946009078	ornithine decarboxylase; Provisional; Region: PRK13578
431946009079	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
431946009080	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
431946009081	homodimer interface [polypeptide binding]; other site
431946009082	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946009083	catalytic residue [active]
431946009084	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
431946009085	Uncharacterized membrane protein, possible Na+ channel or pump [General function prediction only]; Region: COG1811
431946009086	KpsF/GutQ family protein; Region: kpsF; TIGR00393
431946009087	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
431946009088	putative active site [active]
431946009089	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
431946009090	polysaccharide export inner-membrane protein, BexC/CtrB/KpsE family; Region: BexC_CtrB_KpsE; TIGR01010
431946009091	Periplasmic protein involved in polysaccharide export, contains    SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis]; Region: Wza; COG1596
431946009092	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
431946009093	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
431946009094	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
431946009095	Ligand binding site; other site
431946009096	oligomer interface; other site
431946009097	Capsule polysaccharide export protein [Cell envelope biogenesis, outer membrane]; Region: KpsC; COG3563
431946009098	Capsule polysaccharide export protein [Cell envelope biogenesis, outer membrane]; Region: KpsS; COG3562
431946009099	Capsule polysaccharide biosynthesis protein; Region: Capsule_synth; pfam05159
431946009100	accessory Sec system glycosylation protein GtfA; Region: TIGR02918
431946009101	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
431946009102	Tetratricopeptide repeat; Region: TPR_16; pfam13432
431946009103	Capsule polysaccharide export protein [Cell envelope biogenesis, outer membrane]; Region: KpsS; COG3562
431946009104	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
431946009105	Glycosyltransferase family 28 C-terminal domain; Region: Glyco_tran_28_C; cl17369
431946009106	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK13964
431946009107	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
431946009108	active site
431946009109	nucleotide binding site [chemical binding]; other site
431946009110	HIGH motif; other site
431946009111	KMSKS motif; other site
431946009112	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
431946009113	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
431946009114	Walker A/P-loop; other site
431946009115	ATP binding site [chemical binding]; other site
431946009116	Q-loop/lid; other site
431946009117	ABC transporter signature motif; other site
431946009118	Walker B; other site
431946009119	D-loop; other site
431946009120	H-loop/switch region; other site
431946009121	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
431946009122	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
431946009123	putative general secretion pathway protein YghD; Provisional; Region: PRK09731
431946009124	type II secretion system protein L; Region: typeII_sec_gspL; TIGR01709
431946009125	GspL-like protein; Provisional; Region: PRK09662
431946009126	Type II secretion system (T2SS), protein K; Region: T2SK; pfam03934
431946009127	type II secretion system protein J; Region: gspJ; TIGR01711
431946009128	Type II secretion system (T2SS), protein J; Region: T2SJ; pfam11612
431946009129	Type II secretion system (T2SS), protein I; Region: T2SI; pfam02501
431946009130	Type II transport protein GspH; Region: GspH; pfam12019
431946009131	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
431946009132	type II secretion system protein G; Region: typeII_sec_gspG; TIGR01710
431946009133	Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334
431946009134	type II secretion system protein F; Region: GspF; TIGR02120
431946009135	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
431946009136	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
431946009137	type II secretion system protein E; Region: type_II_gspE; TIGR02533
431946009138	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
431946009139	Walker A motif; other site
431946009140	ATP binding site [chemical binding]; other site
431946009141	Walker B motif; other site
431946009142	type II secretion system protein D; Region: type_II_gspD; TIGR02517
431946009143	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
431946009144	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
431946009145	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
431946009146	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
431946009147	putative type II secretion protein GspC; Provisional; Region: PRK09681
431946009148	Type IV pilus biogenesis; Region: Pilus_PilP; pfam11356
431946009149	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
431946009150	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
431946009151	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
431946009152	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
431946009153	Domain of unknown function (DUF4092); Region: DUF4092; pfam13322
431946009154	Peptidase M60-like family; Region: M60-like; pfam13402
431946009155	glycolate transporter; Provisional; Region: PRK09695
431946009156	L-lactate permease; Region: Lactate_perm; cl00701
431946009157	Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate...; Region: malate_synt_G; cd00728
431946009158	active site
431946009159	hypothetical protein; Provisional; Region: PRK09732
431946009160	glycolate oxidase iron-sulfur subunit; Provisional; Region: glcF; PRK11274
431946009161	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
431946009162	Cysteine-rich domain; Region: CCG; pfam02754
431946009163	Cysteine-rich domain; Region: CCG; pfam02754
431946009164	glycolate oxidase FAD binding subunit; Provisional; Region: glcE; PRK11282
431946009165	FAD binding domain; Region: FAD_binding_4; pfam01565
431946009166	glycolate oxidase subunit GlcD; Provisional; Region: PRK11230
431946009167	FAD binding domain; Region: FAD_binding_4; pfam01565
431946009168	DNA-binding transcriptional regulator GlcC; Provisional; Region: PRK09990
431946009169	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
431946009170	DNA-binding site [nucleotide binding]; DNA binding site
431946009171	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
431946009172	acyl-CoA synthetase; Validated; Region: PRK09192
431946009173	Fatty acyl-AMP ligase (FAAL); Region: FAAL; cd05931
431946009174	acyl-activating enzyme (AAE) consensus motif; other site
431946009175	active site
431946009176	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
431946009177	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
431946009178	NAD(P) binding site [chemical binding]; other site
431946009179	active site
431946009180	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
431946009181	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
431946009182	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
431946009183	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
431946009184	catalytic residue [active]
431946009185	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
431946009186	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
431946009187	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
431946009188	Predicted permeases [General function prediction only]; Region: COG0795
431946009189	Bacterial protein of unknown function (YtfJ_HI0045); Region: YtfJ_HI0045; pfam09695
431946009190	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
431946009191	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
431946009192	Thymidylate kinase [Nucleotide transport and metabolism]; Region: Tmk; COG0125
431946009193	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
431946009194	active site
431946009195	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
431946009196	TMP-binding site; other site
431946009197	ATP-binding site [chemical binding]; other site
431946009198	Thymidylate kinase [Nucleotide transport and metabolism]; Region: Tmk; COG0125
431946009199	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
431946009200	TMP-binding site; other site
431946009201	ATP-binding site [chemical binding]; other site
431946009202	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
431946009203	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
431946009204	bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase; Provisional; Region: PRK10507
431946009205	CHAP domain; Region: CHAP; pfam05257
431946009206	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
431946009207	putative S-transferase; Provisional; Region: PRK11752
431946009208	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
431946009209	C-terminal domain interface [polypeptide binding]; other site
431946009210	GSH binding site (G-site) [chemical binding]; other site
431946009211	dimer interface [polypeptide binding]; other site
431946009212	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
431946009213	dimer interface [polypeptide binding]; other site
431946009214	N-terminal domain interface [polypeptide binding]; other site
431946009215	active site
431946009216	hydrogenase 2 accessory protein HypG; Provisional; Region: PRK10413
431946009217	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
431946009218	hydrogenase nickel incorporation protein HybF; Provisional; Region: PRK12380
431946009219	hydrogenase 2-specific chaperone; Provisional; Region: PRK10465
431946009220	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
431946009221	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
431946009222	putative substrate-binding site; other site
431946009223	nickel binding site [ion binding]; other site
431946009224	hydrogenase 2 large subunit; Provisional; Region: PRK10467
431946009225	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
431946009226	putative hydrogenase 2 b cytochrome subunit; Provisional; Region: PRK10881
431946009227	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
431946009228	hydrogenase 2 protein HybA; Provisional; Region: PRK10882
431946009229	4Fe-4S binding domain; Region: Fer4_6; pfam12837
431946009230	hydrogenase 2 small subunit; Provisional; Region: PRK10468
431946009231	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
431946009232	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
431946009233	Protein of unknown function (DUF2623); Region: DUF2623; pfam11115
431946009234	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
431946009235	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
431946009236	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
431946009237	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
431946009238	active site
431946009239	catalytic tetrad [active]
431946009240	hypothetical protein; Provisional; Region: PRK05208
431946009241	oxidoreductase; Provisional; Region: PRK07985
431946009242	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
431946009243	NAD binding site [chemical binding]; other site
431946009244	metal binding site [ion binding]; metal-binding site
431946009245	active site
431946009246	biopolymer transport protein ExbD; Provisional; Region: PRK11267
431946009247	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
431946009248	biopolymer transport protein ExbB; Provisional; Region: PRK10414
431946009249	cystathionine beta-lyase; Provisional; Region: PRK08114
431946009250	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
431946009251	homodimer interface [polypeptide binding]; other site
431946009252	substrate-cofactor binding pocket; other site
431946009253	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946009254	catalytic residue [active]
431946009255	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
431946009256	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
431946009257	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
431946009258	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
431946009259	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946009260	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946009261	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
431946009262	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
431946009263	dimer interface [polypeptide binding]; other site
431946009264	active site
431946009265	metal binding site [ion binding]; metal-binding site
431946009266	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
431946009267	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
431946009268	active site
431946009269	catalytic tetrad [active]
431946009270	putative outer membrane lipoprotein; Provisional; Region: PRK09973
431946009271	hypothetical protein; Provisional; Region: PRK01254
431946009272	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
431946009273	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
431946009274	Transcriptional regulators [Transcription]; Region: FadR; COG2186
431946009275	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
431946009276	DNA-binding site [nucleotide binding]; DNA binding site
431946009277	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
431946009278	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
431946009279	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
431946009280	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
431946009281	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
431946009282	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
431946009283	putative NAD(P) binding site [chemical binding]; other site
431946009284	catalytic Zn binding site [ion binding]; other site
431946009285	structural Zn binding site [ion binding]; other site
431946009286	Malate/L-lactate dehydrogenases [Energy production and conversion]; Region: COG2055
431946009287	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
431946009288	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; pfam03480
431946009289	TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism]; Region: DctM; COG3090
431946009290	DctM-like transporters; Region: DctM; pfam06808
431946009291	TRAP transporter, DctM subunit; Region: dctM; TIGR00786
431946009292	FtsI repressor; Provisional; Region: PRK10883
431946009293	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
431946009294	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
431946009295	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
431946009296	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
431946009297	putative acyl-acceptor binding pocket; other site
431946009298	DNA topoisomerase IV, A subunit, proteobacterial; Region: parC_Gneg; TIGR01062
431946009299	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
431946009300	CAP-like domain; other site
431946009301	active site
431946009302	primary dimer interface [polypeptide binding]; other site
431946009303	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
431946009304	putative ABC transporter periplasmic-binding protein; Provisional; Region: PRK09755
431946009305	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
431946009306	peptide binding site [polypeptide binding]; other site
431946009307	DNA gyrase inhibitor [DNA replication, recombination, and repair]; Region: COG3449
431946009308	TIGR00156 family protein; Region: TIGR00156
431946009309	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
431946009310	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946009311	active site
431946009312	phosphorylation site [posttranslational modification]
431946009313	intermolecular recognition site; other site
431946009314	dimerization interface [polypeptide binding]; other site
431946009315	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
431946009316	DNA binding site [nucleotide binding]
431946009317	sensor protein QseC; Provisional; Region: PRK10337
431946009318	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
431946009319	dimer interface [polypeptide binding]; other site
431946009320	phosphorylation site [posttranslational modification]
431946009321	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946009322	ATP binding site [chemical binding]; other site
431946009323	Mg2+ binding site [ion binding]; other site
431946009324	G-X-G motif; other site
431946009325	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
431946009326	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
431946009327	Uncharacterized conserved protein [Function unknown]; Region: COG1359
431946009328	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
431946009329	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
431946009330	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cd04795
431946009331	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
431946009332	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
431946009333	siderophore binding site; other site
431946009334	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
431946009335	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
431946009336	ABC-ATPase subunit  interface; other site
431946009337	dimer interface [polypeptide binding]; other site
431946009338	putative PBP binding regions; other site
431946009339	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
431946009340	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
431946009341	dimer interface [polypeptide binding]; other site
431946009342	putative PBP binding regions; other site
431946009343	ABC-ATPase subunit  interface; other site
431946009344	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
431946009345	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
431946009346	Walker A/P-loop; other site
431946009347	ATP binding site [chemical binding]; other site
431946009348	Q-loop/lid; other site
431946009349	ABC transporter signature motif; other site
431946009350	Walker B; other site
431946009351	D-loop; other site
431946009352	H-loop/switch region; other site
431946009353	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
431946009354	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
431946009355	N-terminal plug; other site
431946009356	ligand-binding site [chemical binding]; other site
431946009357	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
431946009358	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946009359	ATP binding site [chemical binding]; other site
431946009360	Mg2+ binding site [ion binding]; other site
431946009361	G-X-G motif; other site
431946009362	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
431946009363	anchoring element; other site
431946009364	dimer interface [polypeptide binding]; other site
431946009365	ATP binding site [chemical binding]; other site
431946009366	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
431946009367	active site
431946009368	metal binding site [ion binding]; metal-binding site
431946009369	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
431946009370	esterase YqiA; Provisional; Region: PRK11071
431946009371	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
431946009372	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
431946009373	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
431946009374	active site
431946009375	metal binding site [ion binding]; metal-binding site
431946009376	hexamer interface [polypeptide binding]; other site
431946009377	putative dehydrogenase; Provisional; Region: PRK11039
431946009378	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
431946009379	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
431946009380	dimer interface [polypeptide binding]; other site
431946009381	ADP-ribose binding site [chemical binding]; other site
431946009382	active site
431946009383	nudix motif; other site
431946009384	metal binding site [ion binding]; metal-binding site
431946009385	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
431946009386	hypothetical protein; Provisional; Region: PRK11653
431946009387	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
431946009388	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
431946009389	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
431946009390	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
431946009391	catalytic residues [active]
431946009392	hinge region; other site
431946009393	alpha helical domain; other site
431946009394	putative disulfide oxidoreductase; Provisional; Region: PRK04307
431946009395	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
431946009396	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
431946009397	putative active site [active]
431946009398	metal binding site [ion binding]; metal-binding site
431946009399	zinc transporter ZupT; Provisional; Region: PRK04201
431946009400	ZIP Zinc transporter; Region: Zip; pfam02535
431946009401	Protein of unknown function (DUF4051); Region: DUF4051; pfam13260
431946009402	putative fimbrial protein; Provisional; Region: PRK09733
431946009403	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
431946009404	PapC N-terminal domain; Region: PapC_N; pfam13954
431946009405	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
431946009406	PapC C-terminal domain; Region: PapC_C; pfam13953
431946009407	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
431946009408	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
431946009409	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
431946009410	Fimbrial protein; Region: Fimbrial; pfam00419
431946009411	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
431946009412	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
431946009413	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
431946009414	glycogen synthesis protein GlgS; Provisional; Region: PRK02922
431946009415	Protein of unknown function (DUF1449); Region: DUF1449; pfam07290
431946009416	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
431946009417	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
431946009418	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
431946009419	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
431946009420	putative ribose interaction site [chemical binding]; other site
431946009421	putative ADP binding site [chemical binding]; other site
431946009422	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
431946009423	active site
431946009424	nucleotide binding site [chemical binding]; other site
431946009425	HIGH motif; other site
431946009426	KMSKS motif; other site
431946009427	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
431946009428	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
431946009429	metal binding triad; other site
431946009430	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
431946009431	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
431946009432	metal binding triad; other site
431946009433	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
431946009434	Uncharacterized conserved protein [Function unknown]; Region: COG3025
431946009435	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
431946009436	putative active site [active]
431946009437	putative metal binding residues [ion binding]; other site
431946009438	signature motif; other site
431946009439	putative triphosphate binding site [ion binding]; other site
431946009440	CHAD domain; Region: CHAD; pfam05235
431946009441	SH3 domain-containing protein; Provisional; Region: PRK10884
431946009442	Bacterial SH3 domain homologues; Region: SH3b; smart00287
431946009443	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
431946009444	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
431946009445	active site
431946009446	NTP binding site [chemical binding]; other site
431946009447	metal binding triad [ion binding]; metal-binding site
431946009448	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
431946009449	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
431946009450	Zn2+ binding site [ion binding]; other site
431946009451	Mg2+ binding site [ion binding]; other site
431946009452	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
431946009453	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
431946009454	homooctamer interface [polypeptide binding]; other site
431946009455	active site
431946009456	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
431946009457	transcriptional activator TtdR; Provisional; Region: PRK09801
431946009458	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946009459	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
431946009460	putative effector binding pocket; other site
431946009461	putative dimerization interface [polypeptide binding]; other site
431946009462	tartrate dehydratase subunit alpha; Validated; Region: PRK08230
431946009463	L(+)-tartrate dehydratase subunit beta; Validated; Region: PRK08228
431946009464	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
431946009465	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
431946009466	transmembrane helices; other site
431946009467	UGMP family protein; Validated; Region: PRK09604
431946009468	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
431946009469	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
431946009470	DNA primase; Validated; Region: dnaG; PRK05667
431946009471	CHC2 zinc finger; Region: zf-CHC2; pfam01807
431946009472	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
431946009473	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
431946009474	active site
431946009475	metal binding site [ion binding]; metal-binding site
431946009476	interdomain interaction site; other site
431946009477	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
431946009478	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
431946009479	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
431946009480	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
431946009481	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
431946009482	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
431946009483	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
431946009484	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
431946009485	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
431946009486	DNA binding residues [nucleotide binding]
431946009487	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
431946009488	active site
431946009489	SUMO-1 interface [polypeptide binding]; other site
431946009490	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
431946009491	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
431946009492	FAD binding pocket [chemical binding]; other site
431946009493	FAD binding motif [chemical binding]; other site
431946009494	phosphate binding motif [ion binding]; other site
431946009495	NAD binding pocket [chemical binding]; other site
431946009496	Predicted transcriptional regulators [Transcription]; Region: COG1695
431946009497	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
431946009498	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
431946009499	PAS fold; Region: PAS_3; pfam08447
431946009500	putative active site [active]
431946009501	heme pocket [chemical binding]; other site
431946009502	HAMP domain; Region: HAMP; pfam00672
431946009503	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
431946009504	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
431946009505	dimer interface [polypeptide binding]; other site
431946009506	putative CheW interface [polypeptide binding]; other site
431946009507	putrescine--2-oxoglutarate aminotransferase; Provisional; Region: PRK11522
431946009508	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
431946009509	inhibitor-cofactor binding pocket; inhibition site
431946009510	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946009511	catalytic residue [active]
431946009512	tRNA-binding-domain-containing CsaA-like proteins. CsaA is a molecular chaperone with export related activities. CsaA has a putative tRNA binding activity. The functional unit of CsaA is a homodimer and this domain acts as a dimerization domain; Region: tRNA_bind_CsaA; cd02798
431946009513	dimer interface [polypeptide binding]; other site
431946009514	putative tRNA-binding site [nucleotide binding]; other site
431946009515	DNA-binding transcriptional repressor EbgR; Provisional; Region: PRK10339
431946009516	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
431946009517	DNA binding site [nucleotide binding]
431946009518	domain linker motif; other site
431946009519	Ligand-binding domain of DNA transcription repressor GalR which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalR; cd01544
431946009520	putative dimerization interface [polypeptide binding]; other site
431946009521	putative ligand binding site [chemical binding]; other site
431946009522	cryptic beta-D-galactosidase subunit alpha; Reviewed; Region: ebgA; PRK10340
431946009523	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
431946009524	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
431946009525	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
431946009526	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
431946009527	cryptic beta-D-galactosidase subunit beta; Reviewed; Region: ebgC; PRK10202
431946009528	inner membrane transporter YjeM; Provisional; Region: PRK15238
431946009529	alpha-glucosidase; Provisional; Region: PRK10137
431946009530	Protein of unknown function, DUF608; Region: DUF608; pfam04685
431946009531	Trehalase; Region: Trehalase; cl17346
431946009532	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
431946009533	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
431946009534	active site
431946009535	FMN binding site [chemical binding]; other site
431946009536	2,4-decadienoyl-CoA binding site; other site
431946009537	catalytic residue [active]
431946009538	4Fe-4S cluster binding site [ion binding]; other site
431946009539	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
431946009540	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
431946009541	non-specific DNA binding site [nucleotide binding]; other site
431946009542	salt bridge; other site
431946009543	sequence-specific DNA binding site [nucleotide binding]; other site
431946009544	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4680
431946009545	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
431946009546	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946009547	S-adenosylmethionine binding site [chemical binding]; other site
431946009548	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
431946009549	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
431946009550	putative active site [active]
431946009551	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
431946009552	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
431946009553	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
431946009554	serine/threonine transporter SstT; Provisional; Region: PRK13628
431946009555	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
431946009556	Bacterial inner membrane protein; Region: Imp-YgjV; pfam10688
431946009557	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
431946009558	galactarate dehydratase; Region: galactar-dH20; TIGR03248
431946009559	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
431946009560	Glucuronate isomerase; Region: UxaC; pfam02614
431946009561	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
431946009562	D-galactonate transporter; Region: 2A0114; TIGR00893
431946009563	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946009564	putative substrate translocation pore; other site
431946009565	DNA-binding transcriptional repressor ExuR; Provisional; Region: PRK11523
431946009566	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
431946009567	DNA-binding site [nucleotide binding]; DNA binding site
431946009568	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
431946009569	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
431946009570	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
431946009571	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
431946009572	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
431946009573	Uncharacterized conserved protein [Function unknown]; Region: ElaB; COG4575
431946009574	Predicted membrane protein [Function unknown]; Region: COG5393
431946009575	YqjK-like protein; Region: YqjK; pfam13997
431946009576	Predicted membrane protein [Function unknown]; Region: COG2259
431946009577	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
431946009578	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
431946009579	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
431946009580	putative dimer interface [polypeptide binding]; other site
431946009581	N-terminal domain interface [polypeptide binding]; other site
431946009582	putative substrate binding pocket (H-site) [chemical binding]; other site
431946009583	Predicted membrane protein [Function unknown]; Region: COG3152
431946009584	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946009585	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
431946009586	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
431946009587	dimerization interface [polypeptide binding]; other site
431946009588	Pirin-related protein [General function prediction only]; Region: COG1741
431946009589	Pirin; Region: Pirin; pfam02678
431946009590	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
431946009591	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
431946009592	serine transporter; Region: stp; TIGR00814
431946009593	L-serine dehydratase TdcG; Provisional; Region: PRK15040
431946009594	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
431946009595	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
431946009596	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
431946009597	homotrimer interaction site [polypeptide binding]; other site
431946009598	putative active site [active]
431946009599	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
431946009600	Pyruvate formate lyase 1; Region: PFL1; cd01678
431946009601	coenzyme A binding site [chemical binding]; other site
431946009602	active site
431946009603	catalytic residues [active]
431946009604	glycine loop; other site
431946009605	propionate/acetate kinase; Provisional; Region: PRK12379
431946009606	Acetokinase family; Region: Acetate_kinase; cl17229
431946009607	threonine/serine transporter TdcC; Provisional; Region: PRK13629
431946009608	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
431946009609	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
431946009610	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
431946009611	tetramer interface [polypeptide binding]; other site
431946009612	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946009613	catalytic residue [active]
431946009614	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
431946009615	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946009616	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
431946009617	putative substrate binding pocket [chemical binding]; other site
431946009618	putative dimerization interface [polypeptide binding]; other site
431946009619	DNA-binding transcriptional activator TdcR; Provisional; Region: PRK11424
431946009620	glycerate kinase I; Provisional; Region: PRK10342
431946009621	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
431946009622	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
431946009623	alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional; Region: PRK10558
431946009624	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946009625	D-galactonate transporter; Region: 2A0114; TIGR00893
431946009626	putative substrate translocation pore; other site
431946009627	galactarate dehydratase; Region: galactar-dH20; TIGR03248
431946009628	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
431946009629	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
431946009630	putative regulator PrlF; Provisional; Region: PRK09974
431946009631	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
431946009632	Toxin with endonuclease activity YhaV; Region: Toxin_YhaV; pfam11663
431946009633	DNA-binding transcriptional regulator AgaR; Provisional; Region: PRK09802
431946009634	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
431946009635	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
431946009636	tagatose 6-phosphate aldolase subunit KbaZ; Provisional; Region: PRK15458
431946009637	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
431946009638	active site
431946009639	phosphorylation site [posttranslational modification]
431946009640	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
431946009641	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
431946009642	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
431946009643	active pocket/dimerization site; other site
431946009644	active site
431946009645	phosphorylation site [posttranslational modification]
431946009646	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
431946009647	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
431946009648	active site
431946009649	dimer interface [polypeptide binding]; other site
431946009650	putative sugar isomerase, AgaS family; Region: agaS_fam; TIGR02815
431946009651	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
431946009652	dimer interface [polypeptide binding]; other site
431946009653	active site
431946009654	AgaS-like protein. AgaS contains a SIS (Sugar ISomerase) domain which is found in many phosphosugar isomerases and phosphosugar binding proteins. AgaS is a putative isomerase in Escherichia coli. It is similar to the glucosamine-6-phosphate synthases; Region: SIS_AgaS_like; cd05010
431946009655	putative active site [active]
431946009656	tagatose-bisphosphate aldolase; Reviewed; Region: kbaY; PRK12738
431946009657	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
431946009658	active site
431946009659	intersubunit interface [polypeptide binding]; other site
431946009660	zinc binding site [ion binding]; other site
431946009661	Na+ binding site [ion binding]; other site
431946009662	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
431946009663	active site
431946009664	phosphorylation site [posttranslational modification]
431946009665	PTS system N-acetylgalactosamine-specific transporter subunit IIC; Provisional; Region: PRK09757
431946009666	PTS system N-acetylgalactosamine-specific transporter subunit IID; Provisional; Region: PRK09855
431946009667	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
431946009668	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
431946009669	active site
431946009670	trimer interface [polypeptide binding]; other site
431946009671	allosteric site; other site
431946009672	active site lid [active]
431946009673	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
431946009674	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
431946009675	putative SAM binding site [chemical binding]; other site
431946009676	putative homodimer interface [polypeptide binding]; other site
431946009677	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
431946009678	Putative lipoprotein [General function prediction only]; Region: LppC; COG3107
431946009679	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
431946009680	putative ligand binding site [chemical binding]; other site
431946009681	TIGR00252 family protein; Region: TIGR00252
431946009682	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
431946009683	dimer interface [polypeptide binding]; other site
431946009684	active site
431946009685	outer membrane lipoprotein; Provisional; Region: PRK11023
431946009686	BON domain; Region: BON; pfam04972
431946009687	BON domain; Region: BON; pfam04972
431946009688	Predicted permease; Region: DUF318; pfam03773
431946009689	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
431946009690	NADH(P)-binding; Region: NAD_binding_10; pfam13460
431946009691	NAD binding site [chemical binding]; other site
431946009692	active site
431946009693	intracellular protease, PfpI family; Region: PfpI; TIGR01382
431946009694	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
431946009695	proposed catalytic triad [active]
431946009696	conserved cys residue [active]
431946009697	hypothetical protein; Provisional; Region: PRK03467
431946009698	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
431946009699	GIY-YIG motif/motif A; other site
431946009700	putative active site [active]
431946009701	putative metal binding site [ion binding]; other site
431946009702	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
431946009703	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
431946009704	Coenzyme A binding pocket [chemical binding]; other site
431946009705	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
431946009706	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
431946009707	Peptidase family U32; Region: Peptidase_U32; pfam01136
431946009708	putative protease; Provisional; Region: PRK15447
431946009709	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
431946009710	hypothetical protein; Provisional; Region: PRK10508
431946009711	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
431946009712	tryptophan permease; Provisional; Region: PRK10483
431946009713	aromatic amino acid transport protein; Region: araaP; TIGR00837
431946009714	ATP-dependent RNA helicase DeaD; Provisional; Region: PRK11634
431946009715	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
431946009716	ATP binding site [chemical binding]; other site
431946009717	Mg++ binding site [ion binding]; other site
431946009718	motif III; other site
431946009719	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
431946009720	nucleotide binding region [chemical binding]; other site
431946009721	ATP-binding site [chemical binding]; other site
431946009722	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
431946009723	putative RNA binding site [nucleotide binding]; other site
431946009724	lipoprotein NlpI; Provisional; Region: PRK11189
431946009725	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
431946009726	binding surface
431946009727	TPR motif; other site
431946009728	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
431946009729	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
431946009730	RNase E interface [polypeptide binding]; other site
431946009731	trimer interface [polypeptide binding]; other site
431946009732	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
431946009733	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
431946009734	RNase E interface [polypeptide binding]; other site
431946009735	trimer interface [polypeptide binding]; other site
431946009736	active site
431946009737	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
431946009738	putative nucleic acid binding region [nucleotide binding]; other site
431946009739	G-X-X-G motif; other site
431946009740	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
431946009741	RNA binding site [nucleotide binding]; other site
431946009742	domain interface; other site
431946009743	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
431946009744	16S/18S rRNA binding site [nucleotide binding]; other site
431946009745	S13e-L30e interaction site [polypeptide binding]; other site
431946009746	25S rRNA binding site [nucleotide binding]; other site
431946009747	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
431946009748	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
431946009749	RNA binding site [nucleotide binding]; other site
431946009750	active site
431946009751	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
431946009752	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
431946009753	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
431946009754	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
431946009755	translation initiation factor IF-2; Region: IF-2; TIGR00487
431946009756	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
431946009757	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
431946009758	G1 box; other site
431946009759	putative GEF interaction site [polypeptide binding]; other site
431946009760	GTP/Mg2+ binding site [chemical binding]; other site
431946009761	Switch I region; other site
431946009762	G2 box; other site
431946009763	G3 box; other site
431946009764	Switch II region; other site
431946009765	G4 box; other site
431946009766	G5 box; other site
431946009767	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
431946009768	Translation-initiation factor 2; Region: IF-2; pfam11987
431946009769	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
431946009770	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
431946009771	NusA N-terminal domain; Region: NusA_N; pfam08529
431946009772	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
431946009773	RNA binding site [nucleotide binding]; other site
431946009774	homodimer interface [polypeptide binding]; other site
431946009775	NusA-like KH domain; Region: KH_5; pfam13184
431946009776	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
431946009777	G-X-X-G motif; other site
431946009778	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
431946009779	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
431946009780	ribosome maturation protein RimP; Reviewed; Region: PRK00092
431946009781	hypothetical protein; Provisional; Region: PRK14641
431946009782	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
431946009783	putative oligomer interface [polypeptide binding]; other site
431946009784	putative RNA binding site [nucleotide binding]; other site
431946009785	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
431946009786	ANP binding site [chemical binding]; other site
431946009787	Substrate Binding Site II [chemical binding]; other site
431946009788	Substrate Binding Site I [chemical binding]; other site
431946009789	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
431946009790	Sulfatase; Region: Sulfatase; pfam00884
431946009791	Preprotein translocase SecG subunit; Region: SecG; pfam03840
431946009792	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
431946009793	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
431946009794	active site
431946009795	substrate binding site [chemical binding]; other site
431946009796	metal binding site [ion binding]; metal-binding site
431946009797	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
431946009798	dihydropteroate synthase; Region: DHPS; TIGR01496
431946009799	substrate binding pocket [chemical binding]; other site
431946009800	dimer interface [polypeptide binding]; other site
431946009801	inhibitor binding site; inhibition site
431946009802	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
431946009803	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946009804	Walker A motif; other site
431946009805	ATP binding site [chemical binding]; other site
431946009806	Walker B motif; other site
431946009807	arginine finger; other site
431946009808	Peptidase family M41; Region: Peptidase_M41; pfam01434
431946009809	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
431946009810	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946009811	S-adenosylmethionine binding site [chemical binding]; other site
431946009812	RNA-binding protein YhbY; Provisional; Region: PRK10343
431946009813	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
431946009814	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
431946009815	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
431946009816	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
431946009817	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
431946009818	GTPase CgtA; Reviewed; Region: obgE; PRK12298
431946009819	GTP1/OBG; Region: GTP1_OBG; pfam01018
431946009820	Obg GTPase; Region: Obg; cd01898
431946009821	G1 box; other site
431946009822	GTP/Mg2+ binding site [chemical binding]; other site
431946009823	Switch I region; other site
431946009824	G2 box; other site
431946009825	G3 box; other site
431946009826	Switch II region; other site
431946009827	G4 box; other site
431946009828	G5 box; other site
431946009829	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
431946009830	EamA-like transporter family; Region: EamA; pfam00892
431946009831	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
431946009832	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
431946009833	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
431946009834	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
431946009835	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
431946009836	substrate binding pocket [chemical binding]; other site
431946009837	chain length determination region; other site
431946009838	substrate-Mg2+ binding site; other site
431946009839	catalytic residues [active]
431946009840	aspartate-rich region 1; other site
431946009841	active site lid residues [active]
431946009842	aspartate-rich region 2; other site
431946009843	DNA-binding transcriptional regulator Nlp; Provisional; Region: PRK10344
431946009844	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
431946009845	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
431946009846	hinge; other site
431946009847	active site
431946009848	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
431946009849	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
431946009850	anti sigma factor interaction site; other site
431946009851	regulatory phosphorylation site [posttranslational modification]; other site
431946009852	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
431946009853	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
431946009854	mce related protein; Region: MCE; pfam02470
431946009855	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
431946009856	conserved hypothetical integral membrane protein; Region: TIGR00056
431946009857	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
431946009858	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
431946009859	Walker A/P-loop; other site
431946009860	ATP binding site [chemical binding]; other site
431946009861	Q-loop/lid; other site
431946009862	ABC transporter signature motif; other site
431946009863	Walker B; other site
431946009864	D-loop; other site
431946009865	H-loop/switch region; other site
431946009866	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
431946009867	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
431946009868	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
431946009869	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
431946009870	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
431946009871	putative active site [active]
431946009872	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
431946009873	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
431946009874	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
431946009875	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
431946009876	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
431946009877	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
431946009878	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
431946009879	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
431946009880	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
431946009881	Walker A/P-loop; other site
431946009882	ATP binding site [chemical binding]; other site
431946009883	Q-loop/lid; other site
431946009884	ABC transporter signature motif; other site
431946009885	Walker B; other site
431946009886	D-loop; other site
431946009887	H-loop/switch region; other site
431946009888	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
431946009889	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
431946009890	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
431946009891	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
431946009892	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
431946009893	30S subunit binding site; other site
431946009894	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
431946009895	active site
431946009896	phosphorylation site [posttranslational modification]
431946009897	P-loop ATPase protein family; Region: ATP_bind_2; pfam03668
431946009898	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
431946009899	dimerization domain swap beta strand [polypeptide binding]; other site
431946009900	regulatory protein interface [polypeptide binding]; other site
431946009901	active site
431946009902	regulatory phosphorylation site [posttranslational modification]; other site
431946009903	hypothetical protein; Provisional; Region: PRK10345
431946009904	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
431946009905	Transglycosylase; Region: Transgly; cl17702
431946009906	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
431946009907	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
431946009908	conserved cys residue [active]
431946009909	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
431946009910	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
431946009911	putative active site [active]
431946009912	heme pocket [chemical binding]; other site
431946009913	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
431946009914	dimer interface [polypeptide binding]; other site
431946009915	phosphorylation site [posttranslational modification]
431946009916	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946009917	ATP binding site [chemical binding]; other site
431946009918	Mg2+ binding site [ion binding]; other site
431946009919	G-X-G motif; other site
431946009920	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946009921	active site
431946009922	phosphorylation site [posttranslational modification]
431946009923	intermolecular recognition site; other site
431946009924	dimerization interface [polypeptide binding]; other site
431946009925	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
431946009926	putative binding surface; other site
431946009927	active site
431946009928	radical SAM protein, TIGR01212 family; Region: TIGR01212
431946009929	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
431946009930	FeS/SAM binding site; other site
431946009931	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
431946009932	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
431946009933	active site
431946009934	dimer interface [polypeptide binding]; other site
431946009935	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
431946009936	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
431946009937	active site
431946009938	FMN binding site [chemical binding]; other site
431946009939	substrate binding site [chemical binding]; other site
431946009940	3Fe-4S cluster binding site [ion binding]; other site
431946009941	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
431946009942	domain interface; other site
431946009943	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
431946009944	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
431946009945	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
431946009946	Domain of unknown function (DUF386); Region: DUF386; cl01047
431946009947	N-acetylmannosamine kinase; Provisional; Region: PRK05082
431946009948	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
431946009949	nucleotide binding site [chemical binding]; other site
431946009950	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
431946009951	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
431946009952	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
431946009953	putative active site cavity [active]
431946009954	putative sialic acid transporter; Provisional; Region: PRK03893
431946009955	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946009956	putative substrate translocation pore; other site
431946009957	N-acetylneuraminate lyase; Region: nanA; TIGR00683
431946009958	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
431946009959	inhibitor site; inhibition site
431946009960	active site
431946009961	dimer interface [polypeptide binding]; other site
431946009962	catalytic residue [active]
431946009963	transcriptional regulator NanR; Provisional; Region: PRK03837
431946009964	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
431946009965	DNA-binding site [nucleotide binding]; DNA binding site
431946009966	FCD domain; Region: FCD; pfam07729
431946009967	Stringent starvation protein B [General function prediction only]; Region: SspB; COG2969
431946009968	stringent starvation protein A; Provisional; Region: sspA; PRK09481
431946009969	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
431946009970	C-terminal domain interface [polypeptide binding]; other site
431946009971	putative GSH binding site (G-site) [chemical binding]; other site
431946009972	dimer interface [polypeptide binding]; other site
431946009973	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
431946009974	dimer interface [polypeptide binding]; other site
431946009975	N-terminal domain interface [polypeptide binding]; other site
431946009976	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
431946009977	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
431946009978	23S rRNA interface [nucleotide binding]; other site
431946009979	L3 interface [polypeptide binding]; other site
431946009980	Predicted ATPase [General function prediction only]; Region: COG1485
431946009981	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
431946009982	hypothetical protein; Provisional; Region: PRK11677
431946009983	serine endoprotease; Provisional; Region: PRK10139
431946009984	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
431946009985	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
431946009986	protein binding site [polypeptide binding]; other site
431946009987	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
431946009988	serine endoprotease; Provisional; Region: PRK10898
431946009989	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
431946009990	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
431946009991	malate dehydrogenase; Provisional; Region: PRK05086
431946009992	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
431946009993	NAD binding site [chemical binding]; other site
431946009994	dimerization interface [polypeptide binding]; other site
431946009995	Substrate binding site [chemical binding]; other site
431946009996	arginine repressor; Provisional; Region: PRK05066
431946009997	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
431946009998	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
431946009999	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
431946010000	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
431946010001	RNAase interaction site [polypeptide binding]; other site
431946010002	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
431946010003	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
431946010004	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
431946010005	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
431946010006	HlyD family secretion protein; Region: HlyD_3; pfam13437
431946010007	efflux system membrane protein; Provisional; Region: PRK11594
431946010008	transcriptional regulator; Provisional; Region: PRK10632
431946010009	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946010010	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
431946010011	putative effector binding pocket; other site
431946010012	dimerization interface [polypeptide binding]; other site
431946010013	protease TldD; Provisional; Region: tldD; PRK10735
431946010014	hypothetical protein; Provisional; Region: PRK10899
431946010015	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
431946010016	ribonuclease G; Provisional; Region: PRK11712
431946010017	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
431946010018	homodimer interface [polypeptide binding]; other site
431946010019	oligonucleotide binding site [chemical binding]; other site
431946010020	Maf-like protein; Region: Maf; pfam02545
431946010021	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
431946010022	active site
431946010023	dimer interface [polypeptide binding]; other site
431946010024	rod shape-determining protein MreD; Provisional; Region: PRK11060
431946010025	rod shape-determining protein MreC; Region: mreC; TIGR00219
431946010026	rod shape-determining protein MreC; Region: MreC; pfam04085
431946010027	rod shape-determining protein MreB; Provisional; Region: PRK13927
431946010028	MreB and similar proteins; Region: MreB_like; cd10225
431946010029	nucleotide binding site [chemical binding]; other site
431946010030	Mg binding site [ion binding]; other site
431946010031	putative protofilament interaction site [polypeptide binding]; other site
431946010032	RodZ interaction site [polypeptide binding]; other site
431946010033	regulatory protein CsrD; Provisional; Region: PRK11059
431946010034	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
431946010035	metal binding site [ion binding]; metal-binding site
431946010036	active site
431946010037	I-site; other site
431946010038	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
431946010039	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
431946010040	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
431946010041	NADP binding site [chemical binding]; other site
431946010042	dimer interface [polypeptide binding]; other site
431946010043	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
431946010044	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
431946010045	carboxyltransferase (CT) interaction site; other site
431946010046	biotinylation site [posttranslational modification]; other site
431946010047	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
431946010048	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
431946010049	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
431946010050	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
431946010051	Aldose 1-epimerase, similar to Escherichia coli c4013; Region: Aldose_epim_Ec_c4013; cd09023
431946010052	active site
431946010053	catalytic residues [active]
431946010054	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
431946010055	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
431946010056	substrate binding site [chemical binding]; other site
431946010057	ATP binding site [chemical binding]; other site
431946010058	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
431946010059	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
431946010060	TM-ABC transporter signature motif; other site
431946010061	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
431946010062	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
431946010063	Walker A/P-loop; other site
431946010064	ATP binding site [chemical binding]; other site
431946010065	Q-loop/lid; other site
431946010066	ABC transporter signature motif; other site
431946010067	Walker B; other site
431946010068	D-loop; other site
431946010069	H-loop/switch region; other site
431946010070	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
431946010071	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
431946010072	Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_12; cd06322
431946010073	putative ligand binding site [chemical binding]; other site
431946010074	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
431946010075	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
431946010076	intersubunit interface [polypeptide binding]; other site
431946010077	active site
431946010078	zinc binding site [ion binding]; other site
431946010079	Na+ binding site [ion binding]; other site
431946010080	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
431946010081	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
431946010082	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
431946010083	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
431946010084	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
431946010085	substrate binding site [chemical binding]; other site
431946010086	ATP binding site [chemical binding]; other site
431946010087	hypothetical protein; Provisional; Region: PRK10633
431946010088	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
431946010089	Na binding site [ion binding]; other site
431946010090	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
431946010091	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
431946010092	tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415
431946010093	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
431946010094	FMN binding site [chemical binding]; other site
431946010095	active site
431946010096	catalytic residues [active]
431946010097	substrate binding site [chemical binding]; other site
431946010098	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
431946010099	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
431946010100	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
431946010101	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946010102	DNA methylase; Region: N6_N4_Mtase; pfam01555
431946010103	Protein of unknown function (DUF2556); Region: DUF2556; pfam10831
431946010104	DNA-binding transcriptional regulator EnvR; Provisional; Region: PRK09975
431946010105	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
431946010106	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
431946010107	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
431946010108	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
431946010109	HlyD family secretion protein; Region: HlyD_3; pfam13437
431946010110	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
431946010111	Protein export membrane protein; Region: SecD_SecF; cl14618
431946010112	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
431946010113	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
431946010114	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
431946010115	substrate binding pocket [chemical binding]; other site
431946010116	membrane-bound complex binding site; other site
431946010117	hinge residues; other site
431946010118	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: BatB; COG4597
431946010119	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946010120	conserved gate region; other site
431946010121	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946010122	dimer interface [polypeptide binding]; other site
431946010123	conserved gate region; other site
431946010124	putative PBP binding loops; other site
431946010125	ABC-ATPase subunit interface; other site
431946010126	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
431946010127	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946010128	dimer interface [polypeptide binding]; other site
431946010129	conserved gate region; other site
431946010130	putative PBP binding loops; other site
431946010131	ABC-ATPase subunit interface; other site
431946010132	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
431946010133	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
431946010134	Walker A/P-loop; other site
431946010135	ATP binding site [chemical binding]; other site
431946010136	Q-loop/lid; other site
431946010137	ABC transporter signature motif; other site
431946010138	Walker B; other site
431946010139	D-loop; other site
431946010140	H-loop/switch region; other site
431946010141	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
431946010142	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
431946010143	trimer interface [polypeptide binding]; other site
431946010144	putative metal binding site [ion binding]; other site
431946010145	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
431946010146	shikimate 5-dehydrogenase; Region: aroE; TIGR00507
431946010147	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
431946010148	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
431946010149	shikimate binding site; other site
431946010150	NAD(P) binding site [chemical binding]; other site
431946010151	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
431946010152	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
431946010153	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
431946010154	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
431946010155	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
431946010156	hypothetical protein; Validated; Region: PRK03430
431946010157	hypothetical protein; Provisional; Region: PRK10736
431946010158	DNA protecting protein DprA; Region: dprA; TIGR00732
431946010159	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
431946010160	active site
431946010161	catalytic residues [active]
431946010162	metal binding site [ion binding]; metal-binding site
431946010163	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
431946010164	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
431946010165	putative active site [active]
431946010166	substrate binding site [chemical binding]; other site
431946010167	putative cosubstrate binding site; other site
431946010168	catalytic site [active]
431946010169	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
431946010170	substrate binding site [chemical binding]; other site
431946010171	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
431946010172	putative RNA binding site [nucleotide binding]; other site
431946010173	16S rRNA methyltransferase B; Provisional; Region: PRK10901
431946010174	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946010175	S-adenosylmethionine binding site [chemical binding]; other site
431946010176	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
431946010177	TrkA-N domain; Region: TrkA_N; pfam02254
431946010178	TrkA-C domain; Region: TrkA_C; pfam02080
431946010179	TrkA-N domain; Region: TrkA_N; pfam02254
431946010180	TrkA-C domain; Region: TrkA_C; pfam02080
431946010181	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
431946010182	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
431946010183	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3036
431946010184	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
431946010185	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
431946010186	DNA binding residues [nucleotide binding]
431946010187	dimer interface [polypeptide binding]; other site
431946010188	metal binding site [ion binding]; metal-binding site
431946010189	hypothetical protein; Provisional; Region: PRK10203
431946010190	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
431946010191	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
431946010192	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
431946010193	alphaNTD homodimer interface [polypeptide binding]; other site
431946010194	alphaNTD - beta interaction site [polypeptide binding]; other site
431946010195	alphaNTD - beta' interaction site [polypeptide binding]; other site
431946010196	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
431946010197	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
431946010198	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
431946010199	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
431946010200	RNA binding surface [nucleotide binding]; other site
431946010201	30S ribosomal protein S11; Validated; Region: PRK05309
431946010202	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
431946010203	30S ribosomal protein S13; Region: bact_S13; TIGR03631
431946010204	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
431946010205	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
431946010206	SecY translocase; Region: SecY; pfam00344
431946010207	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
431946010208	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
431946010209	23S rRNA binding site [nucleotide binding]; other site
431946010210	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
431946010211	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
431946010212	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
431946010213	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
431946010214	23S rRNA interface [nucleotide binding]; other site
431946010215	5S rRNA interface [nucleotide binding]; other site
431946010216	L27 interface [polypeptide binding]; other site
431946010217	L5 interface [polypeptide binding]; other site
431946010218	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
431946010219	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
431946010220	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
431946010221	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
431946010222	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
431946010223	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
431946010224	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
431946010225	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
431946010226	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
431946010227	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
431946010228	RNA binding site [nucleotide binding]; other site
431946010229	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
431946010230	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
431946010231	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
431946010232	23S rRNA interface [nucleotide binding]; other site
431946010233	putative translocon interaction site; other site
431946010234	signal recognition particle (SRP54) interaction site; other site
431946010235	L23 interface [polypeptide binding]; other site
431946010236	trigger factor interaction site; other site
431946010237	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
431946010238	23S rRNA interface [nucleotide binding]; other site
431946010239	5S rRNA interface [nucleotide binding]; other site
431946010240	putative antibiotic binding site [chemical binding]; other site
431946010241	L25 interface [polypeptide binding]; other site
431946010242	L27 interface [polypeptide binding]; other site
431946010243	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
431946010244	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
431946010245	G-X-X-G motif; other site
431946010246	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
431946010247	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
431946010248	protein-rRNA interface [nucleotide binding]; other site
431946010249	putative translocon binding site; other site
431946010250	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
431946010251	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
431946010252	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
431946010253	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
431946010254	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
431946010255	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
431946010256	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
431946010257	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
431946010258	protein secretion protein GspB; Provisional; Region: PRK09697
431946010259	AAA domain; Region: AAA_22; pfam13401
431946010260	AAA ATPase domain; Region: AAA_16; pfam13191
431946010261	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
431946010262	Type II secretory pathway, component PulC [Intracellular trafficking and secretion]; Region: PulC; COG3031
431946010263	Type IV pilus biogenesis; Region: Pilus_PilP; pfam11356
431946010264	type II secretion system protein D; Region: type_II_gspD; TIGR02517
431946010265	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
431946010266	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
431946010267	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
431946010268	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
431946010269	Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulE; COG2804
431946010270	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
431946010271	Walker A motif; other site
431946010272	ATP binding site [chemical binding]; other site
431946010273	Walker B motif; other site
431946010274	type II secretion system protein F; Region: GspF; TIGR02120
431946010275	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
431946010276	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
431946010277	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
431946010278	type II secretion system protein G; Region: typeII_sec_gspG; TIGR01710
431946010279	Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334
431946010280	Type II transport protein GspH; Region: GspH; pfam12019
431946010281	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
431946010282	type II secretion system protein I; Region: gspI; TIGR01707
431946010283	Type II secretion system (T2SS), protein I; Region: T2SI; pfam02501
431946010284	Type II secretory pathway, component PulJ [Intracellular trafficking and secretion]; Region: PulJ; COG4795
431946010285	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
431946010286	Type II secretion system (T2SS), protein J; Region: T2SJ; pfam11612
431946010287	Type II secretory pathway, component PulK [Intracellular trafficking and secretion]; Region: PulK; COG3156
431946010288	Type II secretory pathway, component PulL [Intracellular trafficking and secretion]; Region: PulL; COG3297
431946010289	Type II secretion system (T2SS), protein L; Region: T2SL; pfam05134
431946010290	GspL periplasmic domain; Region: GspL_C; pfam12693
431946010291	Type II secretion system (T2SS), protein M; Region: T2SM; pfam04612
431946010292	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
431946010293	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
431946010294	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
431946010295	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
431946010296	heme binding site [chemical binding]; other site
431946010297	ferroxidase pore; other site
431946010298	ferroxidase diiron center [ion binding]; other site
431946010299	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
431946010300	Chitin/cellulose binding domains of chitinase and related enzymes; Region: ChtBD3; cl00046
431946010301	Chitin/cellulose binding domains of chitinase and related enzymes; Region: ChtBD3; cl00046
431946010302	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
431946010303	aromatic chitin/cellulose binding site residues [chemical binding]; other site
431946010304	PF-ChiA is an uncharacterized chitinase found in the hyperthermophilic archaeon Pyrococcus furiosus with a glycosyl hydrolase family 18 (GH18) catalytic domain as well as a cellulose-binding domain.  Members of this domain family are found not only in...; Region: GH18_PF-ChiA-like; cd06543
431946010305	active site
431946010306	elongation factor Tu; Reviewed; Region: PRK00049
431946010307	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
431946010308	G1 box; other site
431946010309	GEF interaction site [polypeptide binding]; other site
431946010310	GTP/Mg2+ binding site [chemical binding]; other site
431946010311	Switch I region; other site
431946010312	G2 box; other site
431946010313	G3 box; other site
431946010314	Switch II region; other site
431946010315	G4 box; other site
431946010316	G5 box; other site
431946010317	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
431946010318	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
431946010319	Antibiotic Binding Site [chemical binding]; other site
431946010320	elongation factor G; Reviewed; Region: PRK00007
431946010321	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
431946010322	G1 box; other site
431946010323	putative GEF interaction site [polypeptide binding]; other site
431946010324	GTP/Mg2+ binding site [chemical binding]; other site
431946010325	Switch I region; other site
431946010326	G2 box; other site
431946010327	G3 box; other site
431946010328	Switch II region; other site
431946010329	G4 box; other site
431946010330	G5 box; other site
431946010331	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
431946010332	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
431946010333	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
431946010334	30S ribosomal protein S7; Validated; Region: PRK05302
431946010335	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
431946010336	S17 interaction site [polypeptide binding]; other site
431946010337	S8 interaction site; other site
431946010338	16S rRNA interaction site [nucleotide binding]; other site
431946010339	streptomycin interaction site [chemical binding]; other site
431946010340	23S rRNA interaction site [nucleotide binding]; other site
431946010341	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
431946010342	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
431946010343	sulfur relay protein TusC; Validated; Region: PRK00211
431946010344	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
431946010345	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
431946010346	YheO-like PAS domain; Region: PAS_6; pfam08348
431946010347	HTH domain; Region: HTH_22; pfam13309
431946010348	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
431946010349	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
431946010350	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
431946010351	phi X174 lysis protein; Provisional; Region: PRK02793
431946010352	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
431946010353	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
431946010354	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
431946010355	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
431946010356	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
431946010357	TrkA-N domain; Region: TrkA_N; pfam02254
431946010358	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
431946010359	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
431946010360	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
431946010361	Walker A/P-loop; other site
431946010362	ATP binding site [chemical binding]; other site
431946010363	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
431946010364	ABC transporter signature motif; other site
431946010365	Walker B; other site
431946010366	D-loop; other site
431946010367	ABC transporter; Region: ABC_tran_2; pfam12848
431946010368	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
431946010369	putative hydrolase; Provisional; Region: PRK10985
431946010370	hypothetical protein; Provisional; Region: PRK04966
431946010371	Phosphoribulokinase-like (PRK-like) is a family of proteins similar to phosphoribulokinase (PRK), the enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. PRK catalyzes the phosphorylation of D-ribulose 5-phosphate to...; Region: PRK_like; cd02029
431946010372	active site
431946010373	hypothetical protein; Provisional; Region: PRK10738
431946010374	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
431946010375	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
431946010376	ligand binding site [chemical binding]; other site
431946010377	flexible hinge region; other site
431946010378	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
431946010379	putative switch regulator; other site
431946010380	non-specific DNA interactions [nucleotide binding]; other site
431946010381	DNA binding site [nucleotide binding]
431946010382	sequence specific DNA binding site [nucleotide binding]; other site
431946010383	putative cAMP binding site [chemical binding]; other site
431946010384	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
431946010385	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
431946010386	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
431946010387	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
431946010388	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
431946010389	inhibitor-cofactor binding pocket; inhibition site
431946010390	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946010391	catalytic residue [active]
431946010392	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
431946010393	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
431946010394	glutamine binding [chemical binding]; other site
431946010395	catalytic triad [active]
431946010396	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
431946010397	cell filamentation protein Fic; Provisional; Region: PRK10347
431946010398	hypothetical protein; Provisional; Region: PRK10204
431946010399	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
431946010400	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
431946010401	substrate binding site [chemical binding]; other site
431946010402	putative transporter; Provisional; Region: PRK03699
431946010403	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946010404	putative substrate translocation pore; other site
431946010405	nitrite reductase subunit NirD; Provisional; Region: PRK14989
431946010406	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
431946010407	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
431946010408	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
431946010409	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
431946010410	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
431946010411	nitrite transporter NirC; Provisional; Region: PRK11562
431946010412	siroheme synthase; Provisional; Region: cysG; PRK10637
431946010413	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
431946010414	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
431946010415	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
431946010416	active site
431946010417	SAM binding site [chemical binding]; other site
431946010418	homodimer interface [polypeptide binding]; other site
431946010419	Protein of unknown function (DUF4223); Region: DUF4223; pfam13978
431946010420	DNA topoisomerase III, bacteria and conjugative plasmid; Region: topB; TIGR01056
431946010421	Protein of unknown function; Region: YhfT; pfam10797
431946010422	Protein of unknown function DUF2620; Region: DUF2620; pfam10941
431946010423	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
431946010424	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
431946010425	active site
431946010426	substrate binding pocket [chemical binding]; other site
431946010427	homodimer interaction site [polypeptide binding]; other site
431946010428	putative mutase; Provisional; Region: PRK12383
431946010429	Phosphopentomutase [Carbohydrate transport and metabolism]; Region: DeoB; COG1015
431946010430	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme yhfX; Region: PLPDE_III_yhfX_like; cd06811
431946010431	dimer interface [polypeptide binding]; other site
431946010432	Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457
431946010433	active site
431946010434	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
431946010435	substrate binding site [chemical binding]; other site
431946010436	catalytic residue [active]
431946010437	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
431946010438	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
431946010439	active site
431946010440	HIGH motif; other site
431946010441	dimer interface [polypeptide binding]; other site
431946010442	KMSKS motif; other site
431946010443	phosphoglycolate phosphatase; Provisional; Region: PRK13222
431946010444	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
431946010445	motif II; other site
431946010446	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
431946010447	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
431946010448	substrate binding site [chemical binding]; other site
431946010449	hexamer interface [polypeptide binding]; other site
431946010450	metal binding site [ion binding]; metal-binding site
431946010451	DNA adenine methylase; Provisional; Region: PRK10904
431946010452	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DamX; COG3266
431946010453	cell division protein DamX; Validated; Region: PRK10905
431946010454	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
431946010455	active site
431946010456	dimer interface [polypeptide binding]; other site
431946010457	metal binding site [ion binding]; metal-binding site
431946010458	shikimate kinase; Reviewed; Region: aroK; PRK00131
431946010459	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
431946010460	ADP binding site [chemical binding]; other site
431946010461	magnesium binding site [ion binding]; other site
431946010462	putative shikimate binding site; other site
431946010463	outer membrane porin HofQ; Provisional; Region: hofQ; PRK10560
431946010464	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
431946010465	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
431946010466	Protein of unknown function (DUF2531); Region: DUF2531; pfam10748
431946010467	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
431946010468	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
431946010469	Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972
431946010470	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
431946010471	Transglycosylase; Region: Transgly; pfam00912
431946010472	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
431946010473	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
431946010474	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
431946010475	ADP-ribose binding site [chemical binding]; other site
431946010476	dimer interface [polypeptide binding]; other site
431946010477	active site
431946010478	nudix motif; other site
431946010479	metal binding site [ion binding]; metal-binding site
431946010480	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
431946010481	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
431946010482	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
431946010483	motif II; other site
431946010484	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
431946010485	RNA binding surface [nucleotide binding]; other site
431946010486	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
431946010487	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
431946010488	dimerization interface [polypeptide binding]; other site
431946010489	domain crossover interface; other site
431946010490	redox-dependent activation switch; other site
431946010491	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
431946010492	Probable transposase; Region: OrfB_IS605; pfam01385
431946010493	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
431946010494	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
431946010495	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
431946010496	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
431946010497	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
431946010498	active site
431946010499	substrate-binding site [chemical binding]; other site
431946010500	metal-binding site [ion binding]
431946010501	ATP binding site [chemical binding]; other site
431946010502	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
431946010503	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
431946010504	dimerization interface [polypeptide binding]; other site
431946010505	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
431946010506	dimer interface [polypeptide binding]; other site
431946010507	phosphorylation site [posttranslational modification]
431946010508	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946010509	ATP binding site [chemical binding]; other site
431946010510	G-X-G motif; other site
431946010511	osmolarity response regulator; Provisional; Region: ompR; PRK09468
431946010512	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946010513	active site
431946010514	phosphorylation site [posttranslational modification]
431946010515	intermolecular recognition site; other site
431946010516	dimerization interface [polypeptide binding]; other site
431946010517	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
431946010518	DNA binding site [nucleotide binding]
431946010519	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
431946010520	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
431946010521	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
431946010522	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
431946010523	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
431946010524	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
431946010525	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
431946010526	RNA binding site [nucleotide binding]; other site
431946010527	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
431946010528	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
431946010529	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
431946010530	G1 box; other site
431946010531	GTP/Mg2+ binding site [chemical binding]; other site
431946010532	Switch I region; other site
431946010533	G2 box; other site
431946010534	G3 box; other site
431946010535	Switch II region; other site
431946010536	G4 box; other site
431946010537	G5 box; other site
431946010538	Nucleoside recognition; Region: Gate; pfam07670
431946010539	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
431946010540	Nucleoside recognition; Region: Gate; pfam07670
431946010541	ferrous iron transport protein FeoC; Provisional; Region: PRK15431
431946010542	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
431946010543	carboxylesterase BioH; Provisional; Region: PRK10349
431946010544	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
431946010545	DNA utilization protein GntX; Provisional; Region: PRK11595
431946010546	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
431946010547	active site
431946010548	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
431946010549	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
431946010550	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
431946010551	high-affinity gluconate transporter; Provisional; Region: PRK14984
431946010552	gluconate transporter; Region: gntP; TIGR00791
431946010553	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
431946010554	4-alpha-glucanotransferase; Region: Glyco_hydro_77; cl00711
431946010555	maltodextrin phosphorylase; Provisional; Region: PRK14985
431946010556	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
431946010557	homodimer interface [polypeptide binding]; other site
431946010558	active site pocket [active]
431946010559	transcriptional regulator MalT; Provisional; Region: PRK04841
431946010560	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
431946010561	DNA binding residues [nucleotide binding]
431946010562	This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while  RTPC has 3 similar repeats...; Region: EPT_RTPC-like; cl00288
431946010563	putative active site [active]
431946010564	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
431946010565	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
431946010566	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
431946010567	intramembrane serine protease GlpG; Provisional; Region: PRK10907
431946010568	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
431946010569	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
431946010570	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
431946010571	active site residue [active]
431946010572	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
431946010573	ABC-type phosphate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PstS; COG0226
431946010574	glycogen phosphorylase; Provisional; Region: PRK14986
431946010575	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
431946010576	homodimer interface [polypeptide binding]; other site
431946010577	active site pocket [active]
431946010578	glycogen synthase; Provisional; Region: glgA; PRK00654
431946010579	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
431946010580	ADP-binding pocket [chemical binding]; other site
431946010581	homodimer interface [polypeptide binding]; other site
431946010582	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
431946010583	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
431946010584	ligand binding site; other site
431946010585	oligomer interface; other site
431946010586	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
431946010587	sulfate 1 binding site; other site
431946010588	glycogen debranching enzyme; Provisional; Region: PRK03705
431946010589	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
431946010590	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
431946010591	active site
431946010592	catalytic site [active]
431946010593	glycogen branching enzyme; Provisional; Region: PRK05402
431946010594	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
431946010595	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
431946010596	active site
431946010597	catalytic site [active]
431946010598	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
431946010599	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
431946010600	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
431946010601	putative antibiotic transporter; Provisional; Region: PRK10739
431946010602	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
431946010603	DNA protecting protein DprA; Region: dprA; TIGR00732
431946010604	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
431946010605	non-specific DNA interactions [nucleotide binding]; other site
431946010606	DNA binding site [nucleotide binding]
431946010607	sequence specific DNA binding site [nucleotide binding]; other site
431946010608	putative cAMP binding site [chemical binding]; other site
431946010609	Superfamily II DNA helicase [DNA replication, recombination, and repair]; Region: RecQ; COG0514
431946010610	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
431946010611	ATP binding site [chemical binding]; other site
431946010612	putative Mg++ binding site [ion binding]; other site
431946010613	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
431946010614	nucleotide binding region [chemical binding]; other site
431946010615	ATP-binding site [chemical binding]; other site
431946010616	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
431946010617	active site
431946010618	low affinity gluconate transporter; Provisional; Region: PRK10472
431946010619	gluconate transporter; Region: gntP; TIGR00791
431946010620	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
431946010621	Shikimate kinase; Region: SKI; pfam01202
431946010622	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
431946010623	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
431946010624	DNA binding site [nucleotide binding]
431946010625	domain linker motif; other site
431946010626	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
431946010627	putative ligand binding site [chemical binding]; other site
431946010628	putative dimerization interface [polypeptide binding]; other site
431946010629	Pirin-related protein [General function prediction only]; Region: COG1741
431946010630	Pirin; Region: Pirin; pfam02678
431946010631	putative oxidoreductase; Provisional; Region: PRK10206
431946010632	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
431946010633	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
431946010634	putative acetyltransferase YhhY; Provisional; Region: PRK10140
431946010635	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
431946010636	Coenzyme A binding pocket [chemical binding]; other site
431946010637	gamma-glutamyltranspeptidase; Reviewed; Region: ggt; PRK09615
431946010638	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
431946010639	hypothetical protein; Provisional; Region: PRK10350
431946010640	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
431946010641	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
431946010642	putative active site [active]
431946010643	catalytic site [active]
431946010644	putative metal binding site [ion binding]; other site
431946010645	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
431946010646	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
431946010647	Walker A/P-loop; other site
431946010648	ATP binding site [chemical binding]; other site
431946010649	Q-loop/lid; other site
431946010650	ABC transporter signature motif; other site
431946010651	Walker B; other site
431946010652	D-loop; other site
431946010653	H-loop/switch region; other site
431946010654	TOBE domain; Region: TOBE_2; pfam08402
431946010655	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
431946010656	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946010657	dimer interface [polypeptide binding]; other site
431946010658	conserved gate region; other site
431946010659	putative PBP binding loops; other site
431946010660	ABC-ATPase subunit interface; other site
431946010661	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
431946010662	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946010663	dimer interface [polypeptide binding]; other site
431946010664	conserved gate region; other site
431946010665	putative PBP binding loops; other site
431946010666	ABC-ATPase subunit interface; other site
431946010667	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
431946010668	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
431946010669	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
431946010670	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
431946010671	Walker A/P-loop; other site
431946010672	ATP binding site [chemical binding]; other site
431946010673	Q-loop/lid; other site
431946010674	ABC transporter signature motif; other site
431946010675	Walker B; other site
431946010676	D-loop; other site
431946010677	H-loop/switch region; other site
431946010678	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
431946010679	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
431946010680	Walker A/P-loop; other site
431946010681	ATP binding site [chemical binding]; other site
431946010682	Q-loop/lid; other site
431946010683	ABC transporter signature motif; other site
431946010684	Walker B; other site
431946010685	D-loop; other site
431946010686	H-loop/switch region; other site
431946010687	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
431946010688	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
431946010689	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
431946010690	TM-ABC transporter signature motif; other site
431946010691	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
431946010692	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
431946010693	TM-ABC transporter signature motif; other site
431946010694	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
431946010695	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
431946010696	dimerization interface [polypeptide binding]; other site
431946010697	ligand binding site [chemical binding]; other site
431946010698	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
431946010699	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
431946010700	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4453
431946010701	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
431946010702	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
431946010703	dimerization interface [polypeptide binding]; other site
431946010704	ligand binding site [chemical binding]; other site
431946010705	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
431946010706	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
431946010707	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
431946010708	DNA binding residues [nucleotide binding]
431946010709	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
431946010710	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
431946010711	cell division protein FtsE; Provisional; Region: PRK10908
431946010712	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
431946010713	Walker A/P-loop; other site
431946010714	ATP binding site [chemical binding]; other site
431946010715	Q-loop/lid; other site
431946010716	ABC transporter signature motif; other site
431946010717	Walker B; other site
431946010718	D-loop; other site
431946010719	H-loop/switch region; other site
431946010720	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
431946010721	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
431946010722	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
431946010723	P loop; other site
431946010724	GTP binding site [chemical binding]; other site
431946010725	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
431946010726	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946010727	S-adenosylmethionine binding site [chemical binding]; other site
431946010728	hypothetical protein; Provisional; Region: PRK10910
431946010729	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
431946010730	Predicted membrane protein [Function unknown]; Region: COG3714
431946010731	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
431946010732	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
431946010733	metal-binding site [ion binding]
431946010734	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
431946010735	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
431946010736	CPxP  motif; other site
431946010737	hypothetical protein; Provisional; Region: PRK11212
431946010738	hypothetical protein; Provisional; Region: PRK11615
431946010739	major facilitator superfamily transporter; Provisional; Region: PRK05122
431946010740	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946010741	putative substrate translocation pore; other site
431946010742	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
431946010743	Domain of unknown function DUF20; Region: UPF0118; pfam01594
431946010744	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
431946010745	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
431946010746	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
431946010747	The substrate-binding component of an ABC-type nickel import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA; cd08489
431946010748	substrate binding site [chemical binding]; other site
431946010749	nickel transporter permease NikB; Provisional; Region: PRK10352
431946010750	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946010751	dimer interface [polypeptide binding]; other site
431946010752	conserved gate region; other site
431946010753	putative PBP binding loops; other site
431946010754	ABC-ATPase subunit interface; other site
431946010755	nickel transporter permease NikC; Provisional; Region: nikC; PRK10417
431946010756	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946010757	dimer interface [polypeptide binding]; other site
431946010758	conserved gate region; other site
431946010759	putative PBP binding loops; other site
431946010760	ABC-ATPase subunit interface; other site
431946010761	nickel transporter ATP-binding protein NikD; Provisional; Region: nikD; PRK10418
431946010762	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
431946010763	Walker A/P-loop; other site
431946010764	ATP binding site [chemical binding]; other site
431946010765	Q-loop/lid; other site
431946010766	ABC transporter signature motif; other site
431946010767	Walker B; other site
431946010768	D-loop; other site
431946010769	H-loop/switch region; other site
431946010770	nickel transporter ATP-binding protein NikE; Provisional; Region: nikE; PRK10419
431946010771	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
431946010772	Walker A/P-loop; other site
431946010773	ATP binding site [chemical binding]; other site
431946010774	Q-loop/lid; other site
431946010775	ABC transporter signature motif; other site
431946010776	Walker B; other site
431946010777	D-loop; other site
431946010778	H-loop/switch region; other site
431946010779	nickel responsive regulator; Provisional; Region: PRK02967
431946010780	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
431946010781	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
431946010782	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
431946010783	DNA-binding site [nucleotide binding]; DNA binding site
431946010784	UTRA domain; Region: UTRA; pfam07702
431946010785	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
431946010786	active site
431946010787	phosphorylation site [posttranslational modification]
431946010788	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
431946010789	active site
431946010790	P-loop; other site
431946010791	phosphorylation site [posttranslational modification]
431946010792	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
431946010793	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
431946010794	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
431946010795	uncharacterized subgroup; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_1; cd07774
431946010796	putative N- and C-terminal domain interface [polypeptide binding]; other site
431946010797	putative active site [active]
431946010798	putative MgATP binding site [chemical binding]; other site
431946010799	catalytic site [active]
431946010800	metal binding site [ion binding]; metal-binding site
431946010801	putative carbohydrate binding site [chemical binding]; other site
431946010802	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
431946010803	dimerization domain swap beta strand [polypeptide binding]; other site
431946010804	regulatory protein interface [polypeptide binding]; other site
431946010805	active site
431946010806	regulatory phosphorylation site [posttranslational modification]; other site
431946010807	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
431946010808	intersubunit interface [polypeptide binding]; other site
431946010809	active site
431946010810	zinc binding site [ion binding]; other site
431946010811	Na+ binding site [ion binding]; other site
431946010812	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
431946010813	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
431946010814	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
431946010815	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
431946010816	Walker A/P-loop; other site
431946010817	ATP binding site [chemical binding]; other site
431946010818	Q-loop/lid; other site
431946010819	ABC transporter signature motif; other site
431946010820	Walker B; other site
431946010821	D-loop; other site
431946010822	H-loop/switch region; other site
431946010823	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
431946010824	Walker A/P-loop; other site
431946010825	ATP binding site [chemical binding]; other site
431946010826	Q-loop/lid; other site
431946010827	ABC transporter signature motif; other site
431946010828	Walker B; other site
431946010829	D-loop; other site
431946010830	H-loop/switch region; other site
431946010831	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
431946010832	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
431946010833	HlyD family secretion protein; Region: HlyD; pfam00529
431946010834	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
431946010835	HlyD family secretion protein; Region: HlyD_3; pfam13437
431946010836	Protein of unknown function (DUF2776); Region: DUF2776; pfam10951
431946010837	Predicted flavoproteins [General function prediction only]; Region: COG2081
431946010838	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
431946010839	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
431946010840	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
431946010841	universal stress protein UspB; Provisional; Region: PRK04960
431946010842	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
431946010843	Ligand Binding Site [chemical binding]; other site
431946010844	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
431946010845	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946010846	POT family; Region: PTR2; pfam00854
431946010847	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946010848	S-adenosylmethionine binding site [chemical binding]; other site
431946010849	oligopeptidase A; Provisional; Region: PRK10911
431946010850	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
431946010851	active site
431946010852	Zn binding site [ion binding]; other site
431946010853	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
431946010854	glutathione reductase; Validated; Region: PRK06116
431946010855	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
431946010856	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
431946010857	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
431946010858	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
431946010859	ArsC family; Region: ArsC; pfam03960
431946010860	catalytic residues [active]
431946010861	outer membrane lipoprotein, Slp family; Region: slp; TIGR00752
431946010862	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
431946010863	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
431946010864	DNA binding residues [nucleotide binding]
431946010865	dimerization interface [polypeptide binding]; other site
431946010866	Putative heme degradation protein [Inorganic ion transport and metabolism]; Region: HemS; COG3720
431946010867	Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171
431946010868	Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171
431946010869	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
431946010870	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
431946010871	N-terminal plug; other site
431946010872	ligand-binding site [chemical binding]; other site
431946010873	ABC-type hemin transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: ChuT; COG4558
431946010874	Hemin binding protein HutB.  These proteins have been shown to function as initial receptors in ABC transport of hemin and hemoproteins in many eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a...; Region: HutB; cd01149
431946010875	putative hemin binding site; other site
431946010876	coproporphyrinogen III oxidase; Provisional; Region: PRK09058
431946010877	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
431946010878	FeS/SAM binding site; other site
431946010879	Putative heme iron utilization protein [Inorganic ion transport and metabolism]; Region: HugX; COG3721
431946010880	atypical (a) SDRs, subgroup 5; Region: SDR_a5; cd05243
431946010881	NADH(P)-binding; Region: NAD_binding_10; pfam13460
431946010882	NAD(P) binding site [chemical binding]; other site
431946010883	putative active site [active]
431946010884	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
431946010885	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
431946010886	ABC-ATPase subunit  interface; other site
431946010887	dimer interface [polypeptide binding]; other site
431946010888	putative PBP binding regions; other site
431946010889	ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; Region: COG4559
431946010890	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
431946010891	Walker A/P-loop; other site
431946010892	ATP binding site [chemical binding]; other site
431946010893	Q-loop/lid; other site
431946010894	ABC transporter signature motif; other site
431946010895	Walker B; other site
431946010896	D-loop; other site
431946010897	H-loop/switch region; other site
431946010898	putative Mg(2+) transport ATPase; Provisional; Region: PRK09977
431946010899	MgtC family; Region: MgtC; pfam02308
431946010900	acid-resistance protein; Provisional; Region: hdeB; PRK11566
431946010901	acid-resistance protein; Provisional; Region: PRK10208
431946010902	acid-resistance membrane protein; Provisional; Region: PRK10209
431946010903	Uncharacterized conserved protein [Function unknown]; Region: HdeD; COG3247
431946010904	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
431946010905	pyruvate kinase; Provisional; Region: PRK05826
431946010906	multidrug efflux system protein MdtE; Provisional; Region: PRK09859
431946010907	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
431946010908	HlyD family secretion protein; Region: HlyD_3; pfam13437
431946010909	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
431946010910	Protein export membrane protein; Region: SecD_SecF; cl14618
431946010911	transcriptional regulator YdeO; Provisional; Region: PRK09940
431946010912	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946010913	DNA-binding transcriptional regulator GadX; Provisional; Region: PRK09978
431946010914	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946010915	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
431946010916	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946010917	catalytic residue [active]
431946010918	Haem-binding domain; Region: Haem_bd; pfam14376
431946010919	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
431946010920	trehalase; Provisional; Region: treF; PRK13270
431946010921	Trehalase; Region: Trehalase; pfam01204
431946010922	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
431946010923	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
431946010924	DNA binding residues [nucleotide binding]
431946010925	dimerization interface [polypeptide binding]; other site
431946010926	Transcriptional regulator [Transcription]; Region: LysR; COG0583
431946010927	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946010928	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
431946010929	putative effector binding pocket; other site
431946010930	putative dimerization interface [polypeptide binding]; other site
431946010931	inner membrane protein YhjD; Region: TIGR00766
431946010932	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946010933	metabolite-proton symporter; Region: 2A0106; TIGR00883
431946010934	putative substrate translocation pore; other site
431946010935	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
431946010936	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
431946010937	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
431946010938	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
431946010939	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
431946010940	substrate binding site [chemical binding]; other site
431946010941	ATP binding site [chemical binding]; other site
431946010942	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
431946010943	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
431946010944	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
431946010945	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
431946010946	putative diguanylate cyclase; Provisional; Region: PRK13561
431946010947	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
431946010948	metal binding site [ion binding]; metal-binding site
431946010949	active site
431946010950	I-site; other site
431946010951	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
431946010952	cellulose synthase subunit BcsC; Provisional; Region: PRK11447
431946010953	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
431946010954	binding surface
431946010955	TPR motif; other site
431946010956	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
431946010957	binding surface
431946010958	TPR motif; other site
431946010959	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
431946010960	endo-1,4-D-glucanase; Provisional; Region: PRK11097
431946010961	cellulose synthase regulator protein; Provisional; Region: PRK11114
431946010962	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
431946010963	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
431946010964	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
431946010965	DXD motif; other site
431946010966	PilZ domain; Region: PilZ; pfam07238
431946010967	cell division protein; Provisional; Region: PRK10037
431946010968	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
431946010969	cellulose biosynthesis protein BcsE; Provisional; Region: PRK15045
431946010970	Protein of unknown function (DUF2819); Region: DUF2819; pfam10995
431946010971	celllulose biosynthesis operon protein BcsF/YhjT; Region: cellullose_BcsF; TIGR03493
431946010972	Protein of unknown function (DUF3260); Region: DUF3260; pfam11658
431946010973	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
431946010974	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
431946010975	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
431946010976	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
431946010977	serine transporter; Region: stp; TIGR00814
431946010978	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
431946010979	HipA-like N-terminal domain; Region: HipA_N; pfam07805
431946010980	HipA-like C-terminal domain; Region: HipA_C; pfam07804
431946010981	N-terminal domain of glycoside hydrolase family 94 and related domains; Region: GH94N_like; cl17067
431946010982	HipA N-terminal domain; Region: Couple_hipA; pfam13657
431946010983	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
431946010984	non-specific DNA binding site [nucleotide binding]; other site
431946010985	salt bridge; other site
431946010986	sequence-specific DNA binding site [nucleotide binding]; other site
431946010987	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
431946010988	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
431946010989	Walker A/P-loop; other site
431946010990	ATP binding site [chemical binding]; other site
431946010991	Q-loop/lid; other site
431946010992	ABC transporter signature motif; other site
431946010993	Walker B; other site
431946010994	D-loop; other site
431946010995	H-loop/switch region; other site
431946010996	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
431946010997	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
431946010998	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
431946010999	Walker A/P-loop; other site
431946011000	ATP binding site [chemical binding]; other site
431946011001	Q-loop/lid; other site
431946011002	ABC transporter signature motif; other site
431946011003	Walker B; other site
431946011004	D-loop; other site
431946011005	H-loop/switch region; other site
431946011006	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
431946011007	dipeptide transporter; Provisional; Region: PRK10913
431946011008	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
431946011009	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946011010	dimer interface [polypeptide binding]; other site
431946011011	conserved gate region; other site
431946011012	putative PBP binding loops; other site
431946011013	ABC-ATPase subunit interface; other site
431946011014	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
431946011015	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946011016	dimer interface [polypeptide binding]; other site
431946011017	conserved gate region; other site
431946011018	putative PBP binding loops; other site
431946011019	ABC-ATPase subunit interface; other site
431946011020	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
431946011021	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
431946011022	peptide binding site [polypeptide binding]; other site
431946011023	phosphoethanolamine transferase; Provisional; Region: PRK11560
431946011024	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
431946011025	Sulfatase; Region: Sulfatase; pfam00884
431946011026	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
431946011027	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946011028	putative substrate translocation pore; other site
431946011029	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
431946011030	3-methyl-adenine DNA glycosylase I; Provisional; Region: PRK10353
431946011031	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
431946011032	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
431946011033	Coenzyme A binding pocket [chemical binding]; other site
431946011034	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
431946011035	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
431946011036	molybdopterin cofactor binding site [chemical binding]; other site
431946011037	substrate binding site [chemical binding]; other site
431946011038	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
431946011039	molybdopterin cofactor binding site; other site
431946011040	putative outer membrane lipoprotein; Provisional; Region: PRK10510
431946011041	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
431946011042	ligand binding site [chemical binding]; other site
431946011043	bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409
431946011044	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
431946011045	dimerization interface [polypeptide binding]; other site
431946011046	ligand binding site [chemical binding]; other site
431946011047	NADP binding site [chemical binding]; other site
431946011048	catalytic site [active]
431946011049	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
431946011050	Predicted transcriptional regulator [Transcription]; Region: COG2944
431946011051	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
431946011052	non-specific DNA binding site [nucleotide binding]; other site
431946011053	salt bridge; other site
431946011054	sequence-specific DNA binding site [nucleotide binding]; other site
431946011055	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
431946011056	DNA-binding site [nucleotide binding]; DNA binding site
431946011057	RNA-binding motif; other site
431946011058	small toxic polypeptide; Provisional; Region: PRK09759
431946011059	glycyl-tRNA synthetase, tetrameric type, beta subunit; Region: glyS; TIGR00211
431946011060	DALR anticodon binding domain; Region: DALR_1; pfam05746
431946011061	anticodon binding site; other site
431946011062	tRNA binding surface [nucleotide binding]; other site
431946011063	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
431946011064	dimer interface [polypeptide binding]; other site
431946011065	motif 1; other site
431946011066	active site
431946011067	motif 2; other site
431946011068	motif 3; other site
431946011069	YsaB-like lipoprotein; Region: YsaB; pfam13983
431946011070	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
431946011071	Acyltransferase family; Region: Acyl_transf_3; pfam01757
431946011072	hypothetical protein; Provisional; Region: PRK11383
431946011073	yiaA/B two helix domain; Region: YiaAB; pfam05360
431946011074	yiaA/B two helix domain; Region: YiaAB; pfam05360
431946011075	hypothetical protein; Provisional; Region: PRK11403
431946011076	yiaA/B two helix domain; Region: YiaAB; pfam05360
431946011077	xylulokinase; Provisional; Region: PRK15027
431946011078	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
431946011079	N- and C-terminal domain interface [polypeptide binding]; other site
431946011080	active site
431946011081	MgATP binding site [chemical binding]; other site
431946011082	catalytic site [active]
431946011083	metal binding site [ion binding]; metal-binding site
431946011084	xylulose binding site [chemical binding]; other site
431946011085	homodimer interface [polypeptide binding]; other site
431946011086	xylose isomerase; Provisional; Region: PRK05474
431946011087	xylose isomerase; Region: xylose_isom_A; TIGR02630
431946011088	D-xylose transporter subunit XylF; Provisional; Region: xylF; PRK10355
431946011089	Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_xylose_binding; cd01538
431946011090	putative ligand binding site [chemical binding]; other site
431946011091	xylose transporter ATP-binding subunit; Provisional; Region: PRK13549
431946011092	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
431946011093	Walker A/P-loop; other site
431946011094	ATP binding site [chemical binding]; other site
431946011095	Q-loop/lid; other site
431946011096	ABC transporter signature motif; other site
431946011097	Walker B; other site
431946011098	D-loop; other site
431946011099	H-loop/switch region; other site
431946011100	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
431946011101	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
431946011102	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
431946011103	TM-ABC transporter signature motif; other site
431946011104	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
431946011105	putative dimerization interface [polypeptide binding]; other site
431946011106	Transcriptional regulators [Transcription]; Region: PurR; COG1609
431946011107	putative ligand binding site [chemical binding]; other site
431946011108	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946011109	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
431946011110	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946011111	hypothetical protein; Provisional; Region: PRK10356
431946011112	Uncharacterized FlgJ-related protein [General function prediction only]; Region: Bax; COG2992
431946011113	alpha-amylase; Reviewed; Region: malS; PRK09505
431946011114	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
431946011115	active site
431946011116	catalytic site [active]
431946011117	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
431946011118	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
431946011119	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946011120	homodimer interface [polypeptide binding]; other site
431946011121	catalytic residue [active]
431946011122	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
431946011123	Transcriptional regulator [Transcription]; Region: IclR; COG1414
431946011124	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
431946011125	Bacterial transcriptional regulator; Region: IclR; pfam01614
431946011126	2,3-diketo-L-gulonate reductase; Provisional; Region: PRK13260
431946011127	Domain of unknown function (DUF386); Region: DUF386; pfam04074
431946011128	2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM; Provisional; Region: PRK09877
431946011129	L-dehydroascorbate transporter large permease subunit; Provisional; Region: PRK15060
431946011130	DctM-like transporters; Region: DctM; pfam06808
431946011131	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
431946011132	tripartite ATP-independent periplasmic transporter solute receptor, DctP family; Region: dctP; TIGR00787
431946011133	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
431946011134	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
431946011135	putative N- and C-terminal domain interface [polypeptide binding]; other site
431946011136	putative active site [active]
431946011137	MgATP binding site [chemical binding]; other site
431946011138	catalytic site [active]
431946011139	metal binding site [ion binding]; metal-binding site
431946011140	putative xylulose binding site [chemical binding]; other site
431946011141	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
431946011142	active site
431946011143	dimer interface [polypeptide binding]; other site
431946011144	magnesium binding site [ion binding]; other site
431946011145	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
431946011146	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
431946011147	AP (apurinic/apyrimidinic) site pocket; other site
431946011148	DNA interaction; other site
431946011149	Metal-binding active site; metal-binding site
431946011150	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
431946011151	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
431946011152	intersubunit interface [polypeptide binding]; other site
431946011153	active site
431946011154	Zn2+ binding site [ion binding]; other site
431946011155	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
431946011156	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
431946011157	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946011158	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
431946011159	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
431946011160	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
431946011161	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
431946011162	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like; Region: ALDH_ACDHII-AcoD; cd07116
431946011163	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
431946011164	NAD(P) binding site [chemical binding]; other site
431946011165	catalytic residues [active]
431946011166	Fic family protein [Function unknown]; Region: COG3177
431946011167	Fic/DOC family; Region: Fic; pfam02661
431946011168	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
431946011169	putative alcohol dehydrogenase; Provisional; Region: PRK09860
431946011170	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
431946011171	dimer interface [polypeptide binding]; other site
431946011172	active site
431946011173	metal binding site [ion binding]; metal-binding site
431946011174	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
431946011175	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
431946011176	G1 box; other site
431946011177	putative GEF interaction site [polypeptide binding]; other site
431946011178	GTP/Mg2+ binding site [chemical binding]; other site
431946011179	Switch I region; other site
431946011180	G2 box; other site
431946011181	G3 box; other site
431946011182	Switch II region; other site
431946011183	G4 box; other site
431946011184	G5 box; other site
431946011185	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
431946011186	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
431946011187	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
431946011188	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
431946011189	selenocysteine synthase; Provisional; Region: PRK04311
431946011190	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
431946011191	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
431946011192	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
431946011193	catalytic residue [active]
431946011194	putative glutathione S-transferase; Provisional; Region: PRK10357
431946011195	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
431946011196	putative C-terminal domain interface [polypeptide binding]; other site
431946011197	putative GSH binding site (G-site) [chemical binding]; other site
431946011198	putative dimer interface [polypeptide binding]; other site
431946011199	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
431946011200	dimer interface [polypeptide binding]; other site
431946011201	N-terminal domain interface [polypeptide binding]; other site
431946011202	putative substrate binding pocket (H-site) [chemical binding]; other site
431946011203	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
431946011204	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
431946011205	HlyD family secretion protein; Region: HlyD_3; pfam13437
431946011206	Protein of unknown function (DUF3302); Region: DUF3302; pfam11742
431946011207	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
431946011208	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
431946011209	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
431946011210	active site
431946011211	P-loop; other site
431946011212	phosphorylation site [posttranslational modification]
431946011213	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
431946011214	active site
431946011215	phosphorylation site [posttranslational modification]
431946011216	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
431946011217	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
431946011218	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
431946011219	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
431946011220	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
431946011221	hypothetical protein; Provisional; Region: PRK11020
431946011222	Protein of unknown function (DUF3251); Region: DUF3251; cl08186
431946011223	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
431946011224	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
431946011225	trimer interface [polypeptide binding]; other site
431946011226	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
431946011227	trimer interface [polypeptide binding]; other site
431946011228	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
431946011229	Haemagglutinin; Region: HIM; pfam05662
431946011230	Haemagglutinin; Region: HIM; pfam05662
431946011231	YadA-like C-terminal region; Region: YadA; pfam03895
431946011232	L-lactate permease; Provisional; Region: PRK10420
431946011233	glycolate transporter; Provisional; Region: PRK09695
431946011234	DNA-binding transcriptional repressor LldR; Provisional; Region: PRK10421
431946011235	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
431946011236	DNA-binding site [nucleotide binding]; DNA binding site
431946011237	FCD domain; Region: FCD; pfam07729
431946011238	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
431946011239	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
431946011240	phosphate binding site [ion binding]; other site
431946011241	putative rRNA methylase; Provisional; Region: PRK10358
431946011242	serine acetyltransferase; Provisional; Region: cysE; PRK11132
431946011243	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
431946011244	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
431946011245	trimer interface [polypeptide binding]; other site
431946011246	active site
431946011247	substrate binding site [chemical binding]; other site
431946011248	CoA binding site [chemical binding]; other site
431946011249	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
431946011250	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
431946011251	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
431946011252	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
431946011253	SecA binding site; other site
431946011254	Preprotein binding site; other site
431946011255	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
431946011256	GSH binding site [chemical binding]; other site
431946011257	catalytic residues [active]
431946011258	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
431946011259	active site residue [active]
431946011260	phosphoglyceromutase; Provisional; Region: PRK05434
431946011261	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
431946011262	AmiB activator; Provisional; Region: PRK11637
431946011263	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
431946011264	Peptidase family M23; Region: Peptidase_M23; pfam01551
431946011265	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
431946011266	NodB motif; other site
431946011267	putative active site [active]
431946011268	putative catalytic site [active]
431946011269	Zn binding site [ion binding]; other site
431946011270	putative glycosyl transferase; Provisional; Region: PRK10073
431946011271	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
431946011272	active site
431946011273	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
431946011274	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
431946011275	NAD(P) binding site [chemical binding]; other site
431946011276	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
431946011277	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
431946011278	substrate-cofactor binding pocket; other site
431946011279	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946011280	catalytic residue [active]
431946011281	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
431946011282	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
431946011283	NADP binding site [chemical binding]; other site
431946011284	homopentamer interface [polypeptide binding]; other site
431946011285	substrate binding site [chemical binding]; other site
431946011286	active site
431946011287	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
431946011288	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
431946011289	putative active site [active]
431946011290	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
431946011291	Glycosyltransferase family 9 (heptosyltransferase); Region: Glyco_transf_9; pfam01075
431946011292	putative active site [active]
431946011293	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
431946011294	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
431946011295	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
431946011296	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
431946011297	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK09822
431946011298	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10359
431946011299	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
431946011300	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
431946011301	Ligand binding site; other site
431946011302	metal-binding site
431946011303	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
431946011304	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
431946011305	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
431946011306	Ligand binding site; other site
431946011307	metal-binding site
431946011308	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
431946011309	UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase; Provisional; Region: PRK09922
431946011310	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
431946011311	putative ADP-binding pocket [chemical binding]; other site
431946011312	lipopolysaccharide core heptose(I) kinase RfaP; Provisional; Region: PRK15123
431946011313	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
431946011314	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
431946011315	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
431946011316	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
431946011317	putative active site [active]
431946011318	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
431946011319	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
431946011320	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
431946011321	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
431946011322	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
431946011323	active site
431946011324	(T/H)XGH motif; other site
431946011325	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
431946011326	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
431946011327	DNA binding site [nucleotide binding]
431946011328	catalytic residue [active]
431946011329	H2TH interface [polypeptide binding]; other site
431946011330	putative catalytic residues [active]
431946011331	turnover-facilitating residue; other site
431946011332	intercalation triad [nucleotide binding]; other site
431946011333	8OG recognition residue [nucleotide binding]; other site
431946011334	putative reading head residues; other site
431946011335	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
431946011336	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
431946011337	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
431946011338	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
431946011339	hypothetical protein; Reviewed; Region: PRK00024
431946011340	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
431946011341	MPN+ (JAMM) motif; other site
431946011342	Zinc-binding site [ion binding]; other site
431946011343	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
431946011344	Flavoprotein; Region: Flavoprotein; pfam02441
431946011345	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
431946011346	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
431946011347	trimer interface [polypeptide binding]; other site
431946011348	active site
431946011349	division inhibitor protein; Provisional; Region: slmA; PRK09480
431946011350	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
431946011351	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
431946011352	active site
431946011353	ribonuclease PH; Reviewed; Region: rph; PRK00173
431946011354	Ribonuclease PH; Region: RNase_PH_bact; cd11362
431946011355	hexamer interface [polypeptide binding]; other site
431946011356	active site
431946011357	hypothetical protein; Provisional; Region: PRK11820
431946011358	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
431946011359	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
431946011360	Predicted membrane protein [Function unknown]; Region: COG2860
431946011361	UPF0126 domain; Region: UPF0126; pfam03458
431946011362	UPF0126 domain; Region: UPF0126; pfam03458
431946011363	NAD-dependent DNA ligase LigB; Reviewed; Region: ligB; PRK08097
431946011364	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cl03295
431946011365	nucleotide binding pocket [chemical binding]; other site
431946011366	K-X-D-G motif; other site
431946011367	catalytic site [active]
431946011368	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
431946011369	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
431946011370	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
431946011371	catalytic site [active]
431946011372	G-X2-G-X-G-K; other site
431946011373	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
431946011374	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
431946011375	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
431946011376	Zn2+ binding site [ion binding]; other site
431946011377	Mg2+ binding site [ion binding]; other site
431946011378	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
431946011379	synthetase active site [active]
431946011380	NTP binding site [chemical binding]; other site
431946011381	metal binding site [ion binding]; metal-binding site
431946011382	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
431946011383	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
431946011384	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
431946011385	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
431946011386	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
431946011387	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
431946011388	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
431946011389	generic binding surface II; other site
431946011390	ssDNA binding site; other site
431946011391	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
431946011392	ATP binding site [chemical binding]; other site
431946011393	putative Mg++ binding site [ion binding]; other site
431946011394	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
431946011395	nucleotide binding region [chemical binding]; other site
431946011396	ATP-binding site [chemical binding]; other site
431946011397	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
431946011398	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
431946011399	AsmA family; Region: AsmA; pfam05170
431946011400	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
431946011401	Protein of unknown function (DUF1498); Region: DUF1498; pfam07385
431946011402	fructokinase; Reviewed; Region: PRK09557
431946011403	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
431946011404	nucleotide binding site [chemical binding]; other site
431946011405	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
431946011406	intersubunit interface [polypeptide binding]; other site
431946011407	active site
431946011408	zinc binding site [ion binding]; other site
431946011409	Na+ binding site [ion binding]; other site
431946011410	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
431946011411	intersubunit interface [polypeptide binding]; other site
431946011412	active site
431946011413	zinc binding site [ion binding]; other site
431946011414	Na+ binding site [ion binding]; other site
431946011415	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
431946011416	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
431946011417	active site
431946011418	P-loop; other site
431946011419	phosphorylation site [posttranslational modification]
431946011420	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
431946011421	active site
431946011422	phosphorylation site [posttranslational modification]
431946011423	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
431946011424	HTH domain; Region: HTH_11; pfam08279
431946011425	Mga helix-turn-helix domain; Region: Mga; pfam05043
431946011426	PRD domain; Region: PRD; pfam00874
431946011427	PRD domain; Region: PRD; pfam00874
431946011428	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
431946011429	active site
431946011430	P-loop; other site
431946011431	phosphorylation site [posttranslational modification]
431946011432	putative alpha-glucosidase; Provisional; Region: PRK10658
431946011433	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
431946011434	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
431946011435	active site
431946011436	homotrimer interface [polypeptide binding]; other site
431946011437	catalytic site [active]
431946011438	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
431946011439	putative transporter; Provisional; Region: PRK11462
431946011440	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
431946011441	Virulence protein [General function prediction only]; Region: COG3943
431946011442	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
431946011443	EamA-like transporter family; Region: EamA; pfam00892
431946011444	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
431946011445	EamA-like transporter family; Region: EamA; pfam00892
431946011446	cytoplasmic membrane lipoprotein-28; Provisional; Region: PRK09861
431946011447	lipoprotein, YaeC family; Region: TIGR00363
431946011448	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
431946011449	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946011450	putative substrate translocation pore; other site
431946011451	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4737
431946011452	Predicted transcriptional regulator [Transcription]; Region: COG2944
431946011453	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
431946011454	non-specific DNA binding site [nucleotide binding]; other site
431946011455	salt bridge; other site
431946011456	sequence-specific DNA binding site [nucleotide binding]; other site
431946011457	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
431946011458	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
431946011459	cryptic adenine deaminase; Provisional; Region: PRK10027
431946011460	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
431946011461	Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295
431946011462	active site
431946011463	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
431946011464	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
431946011465	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946011466	putative substrate translocation pore; other site
431946011467	regulatory protein UhpC; Provisional; Region: PRK11663
431946011468	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946011469	putative substrate translocation pore; other site
431946011470	sensory histidine kinase UhpB; Provisional; Region: PRK11644
431946011471	MASE1; Region: MASE1; pfam05231
431946011472	Histidine kinase; Region: HisKA_3; pfam07730
431946011473	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946011474	ATP binding site [chemical binding]; other site
431946011475	Mg2+ binding site [ion binding]; other site
431946011476	G-X-G motif; other site
431946011477	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
431946011478	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946011479	active site
431946011480	phosphorylation site [posttranslational modification]
431946011481	intermolecular recognition site; other site
431946011482	dimerization interface [polypeptide binding]; other site
431946011483	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
431946011484	DNA binding residues [nucleotide binding]
431946011485	dimerization interface [polypeptide binding]; other site
431946011486	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
431946011487	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
431946011488	putative valine binding site [chemical binding]; other site
431946011489	dimer interface [polypeptide binding]; other site
431946011490	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
431946011491	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
431946011492	PYR/PP interface [polypeptide binding]; other site
431946011493	dimer interface [polypeptide binding]; other site
431946011494	TPP binding site [chemical binding]; other site
431946011495	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
431946011496	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
431946011497	TPP-binding site [chemical binding]; other site
431946011498	dimer interface [polypeptide binding]; other site
431946011499	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
431946011500	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946011501	putative substrate translocation pore; other site
431946011502	Arylsulfatase regulator (Fe-S oxidoreductase) [General function prediction only]; Region: AslB; COG0641
431946011503	Domain of unknown function (DUF202); Region: DUF202; pfam02656
431946011504	Predicted membrane protein [Function unknown]; Region: COG2149
431946011505	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
431946011506	Sulfatase; Region: Sulfatase; pfam00884
431946011507	putative transporter; Provisional; Region: PRK10484
431946011508	uncharacterized SLC5 subfamily, Escherichia coli YidK-like; solute binding domain; Region: SLC5sbd_YidK; cd10328
431946011509	Na binding site [ion binding]; other site
431946011510	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
431946011511	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946011512	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
431946011513	putative transporter; Validated; Region: PRK03818
431946011514	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
431946011515	TrkA-C domain; Region: TrkA_C; pfam02080
431946011516	TrkA-C domain; Region: TrkA_C; pfam02080
431946011517	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
431946011518	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
431946011519	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
431946011520	putative dimer interface [polypeptide binding]; other site
431946011521	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
431946011522	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
431946011523	putative dimer interface [polypeptide binding]; other site
431946011524	hypothetical protein; Provisional; Region: PRK11616
431946011525	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
431946011526	putative oxidoreductase; Provisional; Region: PRK11445
431946011527	hypothetical protein; Provisional; Region: PRK07236
431946011528	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946011529	D-galactonate transporter; Region: 2A0114; TIGR00893
431946011530	putative substrate translocation pore; other site
431946011531	galactonate dehydratase; Provisional; Region: PRK14017
431946011532	D-galactonate dehydratase catalyses the dehydration of galactonate to 2-keto-3-deoxygalactnate (KDGal), as part of the D-galactonate nonphosphorolytic catabolic Entner-Doudoroff pathway. D-galactonate dehydratase belongs to the enolase superfamily of...; Region: D-galactonate_dehydratase; cd03325
431946011533	putative active site pocket [active]
431946011534	putative metal binding site [ion binding]; other site
431946011535	2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Reviewed; Region: PRK09140
431946011536	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
431946011537	active site
431946011538	intersubunit interface [polypeptide binding]; other site
431946011539	catalytic residue [active]
431946011540	2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]; Region: DgoK; COG3734
431946011541	2-keto-3-deoxy-galactonokinase; Region: DGOK; pfam05035
431946011542	Transcriptional regulators [Transcription]; Region: FadR; COG2186
431946011543	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
431946011544	DNA-binding site [nucleotide binding]; DNA binding site
431946011545	FCD domain; Region: FCD; pfam07729
431946011546	hypothetical protein; Provisional; Region: PRK10215
431946011547	sugar phosphate phosphatase; Provisional; Region: PRK10513
431946011548	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
431946011549	active site
431946011550	motif I; other site
431946011551	motif II; other site
431946011552	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
431946011553	hypothetical protein; Provisional; Region: PRK11426
431946011554	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
431946011555	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946011556	Mg2+ binding site [ion binding]; other site
431946011557	G-X-G motif; other site
431946011558	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
431946011559	anchoring element; other site
431946011560	dimer interface [polypeptide binding]; other site
431946011561	ATP binding site [chemical binding]; other site
431946011562	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
431946011563	active site
431946011564	putative metal-binding site [ion binding]; other site
431946011565	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
431946011566	recF protein; Region: recf; TIGR00611
431946011567	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
431946011568	Walker A/P-loop; other site
431946011569	ATP binding site [chemical binding]; other site
431946011570	Q-loop/lid; other site
431946011571	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
431946011572	ABC transporter signature motif; other site
431946011573	Walker B; other site
431946011574	D-loop; other site
431946011575	H-loop/switch region; other site
431946011576	DNA polymerase III subunit beta; Validated; Region: PRK05643
431946011577	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
431946011578	putative DNA binding surface [nucleotide binding]; other site
431946011579	dimer interface [polypeptide binding]; other site
431946011580	beta-clamp/clamp loader binding surface; other site
431946011581	beta-clamp/translesion DNA polymerase binding surface; other site
431946011582	DnaA N-terminal domain; Region: DnaA_N; pfam11638
431946011583	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
431946011584	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946011585	Walker A motif; other site
431946011586	ATP binding site [chemical binding]; other site
431946011587	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
431946011588	Walker B motif; other site
431946011589	arginine finger; other site
431946011590	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
431946011591	DnaA box-binding interface [nucleotide binding]; other site
431946011592	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
431946011593	ribonuclease P; Reviewed; Region: rnpA; PRK01732
431946011594	membrane protein insertase; Provisional; Region: PRK01318
431946011595	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
431946011596	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
431946011597	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
431946011598	trmE is a tRNA modification GTPase; Region: trmE; cd04164
431946011599	G1 box; other site
431946011600	GTP/Mg2+ binding site [chemical binding]; other site
431946011601	Switch I region; other site
431946011602	G2 box; other site
431946011603	Switch II region; other site
431946011604	G3 box; other site
431946011605	G4 box; other site
431946011606	G5 box; other site
431946011607	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
431946011608	Tryptophanese operon leader peptide; Region: Tna_leader; pfam08053
431946011609	tryptophanase, leader peptide-associated; Region: tnaA_trp_ase; TIGR02617
431946011610	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
431946011611	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
431946011612	catalytic residue [active]
431946011613	tryptophan permease TnaB; Provisional; Region: PRK09664
431946011614	aromatic amino acid transport protein; Region: araaP; TIGR00837
431946011615	multidrug efflux system protein MdtL; Provisional; Region: PRK10473
431946011616	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946011617	putative substrate translocation pore; other site
431946011618	DNA-binding transcriptional regulator YidZ; Provisional; Region: PRK10216
431946011619	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946011620	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
431946011621	substrate binding pocket [chemical binding]; other site
431946011622	dimerization interface [polypeptide binding]; other site
431946011623	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
431946011624	Predicted flavoprotein [General function prediction only]; Region: COG0431
431946011625	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
431946011626	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
431946011627	6-phosphogluconate phosphatase; Provisional; Region: PRK10563
431946011628	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
431946011629	motif II; other site
431946011630	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
431946011631	Transposase; Region: HTH_Tnp_1; pfam01527
431946011632	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
431946011633	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
431946011634	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
431946011635	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
431946011636	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
431946011637	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
431946011638	putative inner membrane protein; Provisional; Region: PRK09823
431946011639	Uncharacterized protein family (UPF0167); Region: UPF0167; cl01252
431946011640	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
431946011641	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
431946011642	active site
431946011643	trimer interface [polypeptide binding]; other site
431946011644	allosteric site; other site
431946011645	active site lid [active]
431946011646	N-terminal Early set domain associated with the catalytic domain of putative esterases; Region: E_set_Esterase_like_N; cd11294
431946011647	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
431946011648	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
431946011649	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
431946011650	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
431946011651	trimer interface; other site
431946011652	sugar binding site [chemical binding]; other site
431946011653	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
431946011654	beta-galactosidase; Region: BGL; TIGR03356
431946011655	PTS system beta-glucoside-specific transporter subunits IIABC; Provisional; Region: PRK09824
431946011656	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
431946011657	active site turn [active]
431946011658	phosphorylation site [posttranslational modification]
431946011659	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
431946011660	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
431946011661	HPr interaction site; other site
431946011662	glycerol kinase (GK) interaction site [polypeptide binding]; other site
431946011663	active site
431946011664	phosphorylation site [posttranslational modification]
431946011665	transcriptional antiterminator BglG; Provisional; Region: PRK09772
431946011666	CAT RNA binding domain; Region: CAT_RBD; pfam03123
431946011667	PRD domain; Region: PRD; pfam00874
431946011668	PRD domain; Region: PRD; pfam00874
431946011669	transcriptional regulator PhoU; Provisional; Region: PRK11115
431946011670	PhoU domain; Region: PhoU; pfam01895
431946011671	PhoU domain; Region: PhoU; pfam01895
431946011672	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
431946011673	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
431946011674	Walker A/P-loop; other site
431946011675	ATP binding site [chemical binding]; other site
431946011676	Q-loop/lid; other site
431946011677	ABC transporter signature motif; other site
431946011678	Walker B; other site
431946011679	D-loop; other site
431946011680	H-loop/switch region; other site
431946011681	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
431946011682	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946011683	dimer interface [polypeptide binding]; other site
431946011684	conserved gate region; other site
431946011685	putative PBP binding loops; other site
431946011686	ABC-ATPase subunit interface; other site
431946011687	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
431946011688	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946011689	dimer interface [polypeptide binding]; other site
431946011690	conserved gate region; other site
431946011691	putative PBP binding loops; other site
431946011692	ABC-ATPase subunit interface; other site
431946011693	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
431946011694	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
431946011695	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
431946011696	glutaminase active site [active]
431946011697	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
431946011698	dimer interface [polypeptide binding]; other site
431946011699	active site
431946011700	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
431946011701	dimer interface [polypeptide binding]; other site
431946011702	active site
431946011703	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
431946011704	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
431946011705	Substrate binding site; other site
431946011706	Mg++ binding site; other site
431946011707	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
431946011708	active site
431946011709	substrate binding site [chemical binding]; other site
431946011710	CoA binding site [chemical binding]; other site
431946011711	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
431946011712	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
431946011713	gamma subunit interface [polypeptide binding]; other site
431946011714	epsilon subunit interface [polypeptide binding]; other site
431946011715	LBP interface [polypeptide binding]; other site
431946011716	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
431946011717	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
431946011718	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
431946011719	alpha subunit interaction interface [polypeptide binding]; other site
431946011720	Walker A motif; other site
431946011721	ATP binding site [chemical binding]; other site
431946011722	Walker B motif; other site
431946011723	inhibitor binding site; inhibition site
431946011724	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
431946011725	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
431946011726	core domain interface [polypeptide binding]; other site
431946011727	delta subunit interface [polypeptide binding]; other site
431946011728	epsilon subunit interface [polypeptide binding]; other site
431946011729	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
431946011730	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
431946011731	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
431946011732	beta subunit interaction interface [polypeptide binding]; other site
431946011733	Walker A motif; other site
431946011734	ATP binding site [chemical binding]; other site
431946011735	Walker B motif; other site
431946011736	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
431946011737	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
431946011738	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
431946011739	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
431946011740	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
431946011741	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
431946011742	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
431946011743	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
431946011744	F0F1 ATP synthase subunit I; Validated; Region: PRK08049
431946011745	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
431946011746	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946011747	S-adenosylmethionine binding site [chemical binding]; other site
431946011748	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
431946011749	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
431946011750	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
431946011751	FMN-binding protein MioC; Provisional; Region: PRK09004
431946011752	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
431946011753	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
431946011754	putative DNA binding site [nucleotide binding]; other site
431946011755	putative Zn2+ binding site [ion binding]; other site
431946011756	AsnC family; Region: AsnC_trans_reg; pfam01037
431946011757	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
431946011758	dimer interface [polypeptide binding]; other site
431946011759	active site
431946011760	hypothetical protein; Provisional; Region: yieM; PRK10997
431946011761	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
431946011762	metal ion-dependent adhesion site (MIDAS); other site
431946011763	regulatory ATPase RavA; Provisional; Region: PRK13531
431946011764	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946011765	Walker A motif; other site
431946011766	ATP binding site [chemical binding]; other site
431946011767	Walker B motif; other site
431946011768	arginine finger; other site
431946011769	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
431946011770	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
431946011771	potassium uptake protein; Region: kup; TIGR00794
431946011772	D-ribose pyranase; Provisional; Region: PRK11797
431946011773	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
431946011774	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
431946011775	Walker A/P-loop; other site
431946011776	ATP binding site [chemical binding]; other site
431946011777	Q-loop/lid; other site
431946011778	ABC transporter signature motif; other site
431946011779	Walker B; other site
431946011780	D-loop; other site
431946011781	H-loop/switch region; other site
431946011782	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
431946011783	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
431946011784	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
431946011785	TM-ABC transporter signature motif; other site
431946011786	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
431946011787	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
431946011788	ligand binding site [chemical binding]; other site
431946011789	dimerization interface [polypeptide binding]; other site
431946011790	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
431946011791	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
431946011792	substrate binding site [chemical binding]; other site
431946011793	dimer interface [polypeptide binding]; other site
431946011794	ATP binding site [chemical binding]; other site
431946011795	transcriptional repressor RbsR; Provisional; Region: PRK10423
431946011796	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
431946011797	DNA binding site [nucleotide binding]
431946011798	domain linker motif; other site
431946011799	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
431946011800	dimerization interface [polypeptide binding]; other site
431946011801	ligand binding site [chemical binding]; other site
431946011802	putative transporter; Provisional; Region: PRK10504
431946011803	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946011804	putative substrate translocation pore; other site
431946011805	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946011806	Transcriptional regulators [Transcription]; Region: FadR; COG2186
431946011807	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
431946011808	DNA-binding site [nucleotide binding]; DNA binding site
431946011809	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
431946011810	transcriptional regulator HdfR; Provisional; Region: PRK03601
431946011811	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946011812	LysR substrate binding domain; Region: LysR_substrate; pfam03466
431946011813	dimerization interface [polypeptide binding]; other site
431946011814	hypothetical protein; Provisional; Region: PRK11027
431946011815	putative ATP-dependent protease; Provisional; Region: PRK09862
431946011816	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
431946011817	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946011818	Walker A motif; other site
431946011819	ATP binding site [chemical binding]; other site
431946011820	Walker B motif; other site
431946011821	arginine finger; other site
431946011822	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
431946011823	ilvG operon leader peptide; Provisional; Region: PRK10424
431946011824	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
431946011825	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
431946011826	PYR/PP interface [polypeptide binding]; other site
431946011827	dimer interface [polypeptide binding]; other site
431946011828	TPP binding site [chemical binding]; other site
431946011829	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
431946011830	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
431946011831	TPP-binding site [chemical binding]; other site
431946011832	dimer interface [polypeptide binding]; other site
431946011833	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
431946011834	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
431946011835	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
431946011836	homodimer interface [polypeptide binding]; other site
431946011837	substrate-cofactor binding pocket; other site
431946011838	catalytic residue [active]
431946011839	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
431946011840	threonine dehydratase; Reviewed; Region: PRK09224
431946011841	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
431946011842	tetramer interface [polypeptide binding]; other site
431946011843	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946011844	catalytic residue [active]
431946011845	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
431946011846	putative Ile/Val binding site [chemical binding]; other site
431946011847	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
431946011848	putative Ile/Val binding site [chemical binding]; other site
431946011849	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946011850	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
431946011851	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
431946011852	putative dimerization interface [polypeptide binding]; other site
431946011853	ketol-acid reductoisomerase; Validated; Region: PRK05225
431946011854	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
431946011855	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
431946011856	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
431946011857	peptidyl-prolyl cis-trans isomerase C; Provisional; Region: PRK15441
431946011858	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
431946011859	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
431946011860	Part of AAA domain; Region: AAA_19; pfam13245
431946011861	Family description; Region: UvrD_C_2; pfam13538
431946011862	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
431946011863	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
431946011864	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
431946011865	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
431946011866	ATP binding site [chemical binding]; other site
431946011867	Mg++ binding site [ion binding]; other site
431946011868	motif III; other site
431946011869	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
431946011870	nucleotide binding region [chemical binding]; other site
431946011871	ATP-binding site [chemical binding]; other site
431946011872	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
431946011873	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
431946011874	catalytic residues [active]
431946011875	putative rho operon leader peptide; Provisional; Region: PRK09979
431946011876	transcription termination factor Rho; Provisional; Region: rho; PRK09376
431946011877	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
431946011878	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
431946011879	RNA binding site [nucleotide binding]; other site
431946011880	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
431946011881	multimer interface [polypeptide binding]; other site
431946011882	Walker A motif; other site
431946011883	ATP binding site [chemical binding]; other site
431946011884	Walker B motif; other site
431946011885	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
431946011886	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
431946011887	Mg++ binding site [ion binding]; other site
431946011888	putative catalytic motif [active]
431946011889	substrate binding site [chemical binding]; other site
431946011890	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
431946011891	Chain length determinant protein; Region: Wzz; pfam02706
431946011892	UDP-N-acetylglucosamine 2-epimerase; Region: wecB; TIGR00236
431946011893	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
431946011894	active site
431946011895	homodimer interface [polypeptide binding]; other site
431946011896	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
431946011897	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
431946011898	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
431946011899	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
431946011900	dTDP-glucose 4,6-dehydratase; Provisional; Region: PRK10217
431946011901	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
431946011902	NAD binding site [chemical binding]; other site
431946011903	substrate binding site [chemical binding]; other site
431946011904	homodimer interface [polypeptide binding]; other site
431946011905	active site
431946011906	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
431946011907	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
431946011908	substrate binding site; other site
431946011909	tetramer interface; other site
431946011910	TDP-D-fucosamine acetyltransferase; Region: wecD_rffC; TIGR02382
431946011911	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
431946011912	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
431946011913	inhibitor-cofactor binding pocket; inhibition site
431946011914	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946011915	catalytic residue [active]
431946011916	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
431946011917	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
431946011918	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
431946011919	putative common antigen polymerase; Provisional; Region: PRK02975
431946011920	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
431946011921	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
431946011922	putative transport protein YifK; Provisional; Region: PRK10746
431946011923	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
431946011924	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
431946011925	FeS/SAM binding site; other site
431946011926	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
431946011927	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
431946011928	Sulfatase; Region: Sulfatase; pfam00884
431946011929	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
431946011930	HemY protein N-terminus; Region: HemY_N; pfam07219
431946011931	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959
431946011932	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
431946011933	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
431946011934	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
431946011935	active site
431946011936	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
431946011937	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
431946011938	domain interfaces; other site
431946011939	active site
431946011940	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
431946011941	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
431946011942	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
431946011943	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
431946011944	putative iron binding site [ion binding]; other site
431946011945	Predicted small periplasmic lipoprotein [Cell motility and secretion]; Region: COG5567
431946011946	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
431946011947	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
431946011948	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
431946011949	hypothetical protein; Provisional; Region: PRK10963
431946011950	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
431946011951	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
431946011952	active site
431946011953	DNA binding site [nucleotide binding]
431946011954	Int/Topo IB signature motif; other site
431946011955	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
431946011956	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
431946011957	motif II; other site
431946011958	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
431946011959	Part of AAA domain; Region: AAA_19; pfam13245
431946011960	Family description; Region: UvrD_C_2; pfam13538
431946011961	Uncharacterized conserved protein [Function unknown]; Region: COG1912
431946011962	Predicted periplasmic protein [Function unknown]; Region: COG3698
431946011963	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
431946011964	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
431946011965	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
431946011966	Cl binding site [ion binding]; other site
431946011967	oligomer interface [polypeptide binding]; other site
431946011968	Protein of unknown function (DUF2628); Region: DUF2628; pfam10947
431946011969	hypothetical protein; Provisional; Region: PRK11371
431946011970	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
431946011971	EamA-like transporter family; Region: EamA; cl17759
431946011972	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
431946011973	CoenzymeA binding site [chemical binding]; other site
431946011974	subunit interaction site [polypeptide binding]; other site
431946011975	PHB binding site; other site
431946011976	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
431946011977	dimerization interface [polypeptide binding]; other site
431946011978	substrate binding site [chemical binding]; other site
431946011979	active site
431946011980	calcium binding site [ion binding]; other site
431946011981	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
431946011982	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
431946011983	ATP binding site [chemical binding]; other site
431946011984	putative Mg++ binding site [ion binding]; other site
431946011985	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
431946011986	nucleotide binding region [chemical binding]; other site
431946011987	ATP-binding site [chemical binding]; other site
431946011988	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
431946011989	Helicase and RNase D C-terminal; Region: HRDC; smart00341
431946011990	threonine efflux system; Provisional; Region: PRK10229
431946011991	putative transposase; Provisional; Region: PRK09857
431946011992	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
431946011993	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
431946011994	lysophospholipase L2; Provisional; Region: PRK10749
431946011995	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
431946011996	putative hydrolase; Provisional; Region: PRK10976
431946011997	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
431946011998	active site
431946011999	motif I; other site
431946012000	motif II; other site
431946012001	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
431946012002	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
431946012003	EamA-like transporter family; Region: EamA; pfam00892
431946012004	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
431946012005	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946012006	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
431946012007	putative dimerization interface [polypeptide binding]; other site
431946012008	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
431946012009	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
431946012010	THF binding site; other site
431946012011	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
431946012012	substrate binding site [chemical binding]; other site
431946012013	THF binding site; other site
431946012014	zinc-binding site [ion binding]; other site
431946012015	Hexulose-6-phosphate isomerase (PHI). PHI is a member of the SIS (Sugar ISomerase domain) superfamily. In the ribulose monophosphate pathway of formaldehyde fixation, hexulose-6-phosphate synthase catalyzes the condensation of ribulose-5-phosphate with...; Region: SIS_PHI; cd05005
431946012016	tetramer interface [polypeptide binding]; other site
431946012017	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
431946012018	active site
431946012019	PTS system, N-acetylglucosamine-specific IIBC component; Region: PTS-II-BC-nag; TIGR01998
431946012020	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
431946012021	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
431946012022	active site turn [active]
431946012023	phosphorylation site [posttranslational modification]
431946012024	transketolase; Reviewed; Region: PRK12753
431946012025	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
431946012026	TPP-binding site [chemical binding]; other site
431946012027	dimer interface [polypeptide binding]; other site
431946012028	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
431946012029	PYR/PP interface [polypeptide binding]; other site
431946012030	dimer interface [polypeptide binding]; other site
431946012031	TPP binding site [chemical binding]; other site
431946012032	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
431946012033	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
431946012034	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
431946012035	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
431946012036	putative active site [active]
431946012037	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
431946012038	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946012039	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
431946012040	dimerization interface [polypeptide binding]; other site
431946012041	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
431946012042	Na binding site [ion binding]; other site
431946012043	allophanate hydrolase; Provisional; Region: PRK08186
431946012044	carbamate kinase; Reviewed; Region: PRK12686
431946012045	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
431946012046	putative substrate binding site [chemical binding]; other site
431946012047	nucleotide binding site [chemical binding]; other site
431946012048	nucleotide binding site [chemical binding]; other site
431946012049	homodimer interface [polypeptide binding]; other site
431946012050	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
431946012051	CoA binding domain; Region: CoA_binding; pfam02629
431946012052	CoA-ligase; Region: Ligase_CoA; pfam00549
431946012053	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
431946012054	Isochorismatase family; Region: Isochorismatase; pfam00857
431946012055	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
431946012056	catalytic triad [active]
431946012057	conserved cis-peptide bond; other site
431946012058	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
431946012059	uridine phosphorylase; Provisional; Region: PRK11178
431946012060	uridine phosphorylase; Region: Uridine-psphlse; TIGR01718
431946012061	Tripartite tricarboxylate transporter TctA family; Region: TctA; cl00772
431946012062	Tripartite tricarboxylate transporter TctB family; Region: TctB; pfam07331
431946012063	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3181
431946012064	2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Reviewed; Region: PRK09140
431946012065	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
431946012066	active site
431946012067	intersubunit interface [polypeptide binding]; other site
431946012068	catalytic residue [active]
431946012069	2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]; Region: DgoK; COG3734
431946012070	2-keto-3-deoxy-galactonokinase; Region: DGOK; pfam05035
431946012071	Transcriptional regulator [Transcription]; Region: IclR; COG1414
431946012072	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
431946012073	Bacterial transcriptional regulator; Region: IclR; pfam01614
431946012074	DNA recombination protein RmuC; Provisional; Region: PRK10361
431946012075	RmuC family; Region: RmuC; pfam02646
431946012076	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
431946012077	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946012078	S-adenosylmethionine binding site [chemical binding]; other site
431946012079	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
431946012080	SCP-2 sterol transfer family; Region: SCP2; pfam02036
431946012081	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
431946012082	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
431946012083	twin arginine translocase protein A; Provisional; Region: tatA; PRK03554
431946012084	twin arginine translocase protein A; Provisional; Region: tatA; PRK00575
431946012085	sec-independent translocase; Provisional; Region: PRK01770
431946012086	sec-independent translocase; Provisional; Region: tatB; PRK00404
431946012087	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
431946012088	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
431946012089	active site
431946012090	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
431946012091	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
431946012092	KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); Region: KOW; cl00354
431946012093	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
431946012094	FMN reductase; Validated; Region: fre; PRK08051
431946012095	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
431946012096	FAD binding pocket [chemical binding]; other site
431946012097	FAD binding motif [chemical binding]; other site
431946012098	phosphate binding motif [ion binding]; other site
431946012099	beta-alpha-beta structure motif; other site
431946012100	NAD binding pocket [chemical binding]; other site
431946012101	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
431946012102	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
431946012103	dimer interface [polypeptide binding]; other site
431946012104	active site
431946012105	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
431946012106	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
431946012107	substrate binding site [chemical binding]; other site
431946012108	oxyanion hole (OAH) forming residues; other site
431946012109	trimer interface [polypeptide binding]; other site
431946012110	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
431946012111	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
431946012112	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
431946012113	proline dipeptidase; Provisional; Region: PRK13607
431946012114	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
431946012115	active site
431946012116	hypothetical protein; Provisional; Region: PRK11568
431946012117	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
431946012118	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
431946012119	potassium transporter; Provisional; Region: PRK10750
431946012120	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
431946012121	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
431946012122	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
431946012123	Walker A motif; other site
431946012124	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
431946012125	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
431946012126	GTP binding site; other site
431946012127	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
431946012128	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
431946012129	serine/threonine protein kinase; Provisional; Region: PRK11768
431946012130	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
431946012131	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
431946012132	catalytic residues [active]
431946012133	hinge region; other site
431946012134	alpha helical domain; other site
431946012135	hypothetical protein; Provisional; Region: PRK11367
431946012136	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
431946012137	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
431946012138	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
431946012139	putative acyl-acceptor binding pocket; other site
431946012140	DNA polymerase I; Provisional; Region: PRK05755
431946012141	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
431946012142	active site
431946012143	metal binding site 1 [ion binding]; metal-binding site
431946012144	putative 5' ssDNA interaction site; other site
431946012145	metal binding site 3; metal-binding site
431946012146	metal binding site 2 [ion binding]; metal-binding site
431946012147	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
431946012148	putative DNA binding site [nucleotide binding]; other site
431946012149	putative metal binding site [ion binding]; other site
431946012150	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
431946012151	active site
431946012152	catalytic site [active]
431946012153	substrate binding site [chemical binding]; other site
431946012154	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
431946012155	active site
431946012156	DNA binding site [nucleotide binding]
431946012157	catalytic site [active]
431946012158	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
431946012159	G1 box; other site
431946012160	GTP/Mg2+ binding site [chemical binding]; other site
431946012161	Switch I region; other site
431946012162	G2 box; other site
431946012163	G3 box; other site
431946012164	Switch II region; other site
431946012165	G4 box; other site
431946012166	G5 box; other site
431946012167	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3078
431946012168	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
431946012169	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
431946012170	FeS/SAM binding site; other site
431946012171	HemN C-terminal domain; Region: HemN_C; pfam06969
431946012172	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
431946012173	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946012174	active site
431946012175	phosphorylation site [posttranslational modification]
431946012176	intermolecular recognition site; other site
431946012177	dimerization interface [polypeptide binding]; other site
431946012178	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946012179	Walker A motif; other site
431946012180	ATP binding site [chemical binding]; other site
431946012181	Walker B motif; other site
431946012182	arginine finger; other site
431946012183	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
431946012184	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
431946012185	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
431946012186	putative active site [active]
431946012187	heme pocket [chemical binding]; other site
431946012188	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
431946012189	dimer interface [polypeptide binding]; other site
431946012190	phosphorylation site [posttranslational modification]
431946012191	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946012192	ATP binding site [chemical binding]; other site
431946012193	Mg2+ binding site [ion binding]; other site
431946012194	G-X-G motif; other site
431946012195	glutamine synthetase; Provisional; Region: glnA; PRK09469
431946012196	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
431946012197	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
431946012198	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
431946012199	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
431946012200	G1 box; other site
431946012201	putative GEF interaction site [polypeptide binding]; other site
431946012202	GTP/Mg2+ binding site [chemical binding]; other site
431946012203	Switch I region; other site
431946012204	G2 box; other site
431946012205	G3 box; other site
431946012206	Switch II region; other site
431946012207	G4 box; other site
431946012208	G5 box; other site
431946012209	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
431946012210	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
431946012211	outer membrane porin L; Provisional; Region: ompL; PRK09980
431946012212	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
431946012213	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946012214	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
431946012215	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
431946012216	alpha-glucosidase; Provisional; Region: PRK10426
431946012217	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
431946012218	YihQ is a bacterial alpha-glucosidase with a conserved glycosyl hydrolase family 31 (GH31) domain that catalyzes the release of an alpha-glucosyl residue from the non-reducing end of alpha-glucoside substrates such as alpha-glucosyl fluoride. Orthologs...; Region: GH31_glucosidase_YihQ; cd06594
431946012219	putative active site [active]
431946012220	putative catalytic site [active]
431946012221	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
431946012222	Aldose 1-epimerase, similar to Escherichia coli YihR; Region: Aldose_epim_Ec_YihR; cd09022
431946012223	active site
431946012224	catalytic residues [active]
431946012225	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cd00249
431946012226	dimerization interface [polypeptide binding]; other site
431946012227	putative active cleft [active]
431946012228	Tagatose-1,6-bisphosphate aldolase [Carbohydrate transport and metabolism]; Region: LacD; COG3684
431946012229	catalytic residue [active]
431946012230	NADH-dependent gamma-hydroxybutyrate dehydrogenase; Provisional; Region: PRK15461
431946012231	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
431946012232	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
431946012233	Ribokinase-like subgroup B.  Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_B; cd01945
431946012234	substrate binding site [chemical binding]; other site
431946012235	ATP binding site [chemical binding]; other site
431946012236	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
431946012237	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
431946012238	putative DNA binding site [nucleotide binding]; other site
431946012239	putative Zn2+ binding site [ion binding]; other site
431946012240	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
431946012241	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
431946012242	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
431946012243	motif II; other site
431946012244	hypothetical protein; Reviewed; Region: PRK01637
431946012245	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
431946012246	putative active site [active]
431946012247	dimerization interface [polypeptide binding]; other site
431946012248	putative tRNAtyr binding site [nucleotide binding]; other site
431946012249	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
431946012250	Coenzyme A binding pocket [chemical binding]; other site
431946012251	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
431946012252	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
431946012253	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
431946012254	substrate binding pocket [chemical binding]; other site
431946012255	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
431946012256	non-specific DNA binding site [nucleotide binding]; other site
431946012257	salt bridge; other site
431946012258	sequence-specific DNA binding site [nucleotide binding]; other site
431946012259	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
431946012260	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
431946012261	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
431946012262	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
431946012263	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
431946012264	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
431946012265	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
431946012266	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
431946012267	molybdopterin cofactor binding site; other site
431946012268	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
431946012269	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
431946012270	molybdopterin cofactor binding site; other site
431946012271	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
431946012272	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
431946012273	Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones]; Region: HtpG; COG0326
431946012274	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c_3; pfam13589
431946012275	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
431946012276	putative frv operon regulatory protein; Provisional; Region: PRK09863
431946012277	HTH domain; Region: HTH_11; pfam08279
431946012278	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
431946012279	active site
431946012280	phosphorylation site [posttranslational modification]
431946012281	putative peptidase; Provisional; Region: PRK09864
431946012282	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
431946012283	oligomer interface [polypeptide binding]; other site
431946012284	active site
431946012285	metal binding site [ion binding]; metal-binding site
431946012286	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
431946012287	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
431946012288	active site
431946012289	P-loop; other site
431946012290	phosphorylation site [posttranslational modification]
431946012291	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
431946012292	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
431946012293	active site
431946012294	phosphorylation site [posttranslational modification]
431946012295	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
431946012296	L-rhamnose 1-epimerase; Region: YiiL_rotase; TIGR02625
431946012297	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
431946012298	intersubunit interface [polypeptide binding]; other site
431946012299	active site
431946012300	Zn2+ binding site [ion binding]; other site
431946012301	L-rhamnose isomerase; Provisional; Region: PRK01076
431946012302	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
431946012303	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
431946012304	N- and C-terminal domain interface [polypeptide binding]; other site
431946012305	active site
431946012306	putative catalytic site [active]
431946012307	metal binding site [ion binding]; metal-binding site
431946012308	ATP binding site [chemical binding]; other site
431946012309	rhamnulokinase; Provisional; Region: rhaB; PRK10640
431946012310	carbohydrate binding site [chemical binding]; other site
431946012311	transcriptional activator RhaS; Provisional; Region: PRK13503
431946012312	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
431946012313	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946012314	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946012315	transcriptional activator RhaR; Provisional; Region: PRK13500
431946012316	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
431946012317	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946012318	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946012319	L-rhamnose-proton symport protein (RhaT); Region: RhaT; cl05728
431946012320	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
431946012321	superoxide dismutase; Provisional; Region: PRK10925
431946012322	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
431946012323	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
431946012324	2-keto-3-deoxygluconate transporter; Region: kdgT; TIGR00793
431946012325	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
431946012326	MOSC domain; Region: MOSC; pfam03473
431946012327	3-alpha domain; Region: 3-alpha; pfam03475
431946012328	two-component sensor protein; Provisional; Region: cpxA; PRK09470
431946012329	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
431946012330	dimerization interface [polypeptide binding]; other site
431946012331	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
431946012332	dimer interface [polypeptide binding]; other site
431946012333	phosphorylation site [posttranslational modification]
431946012334	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946012335	ATP binding site [chemical binding]; other site
431946012336	Mg2+ binding site [ion binding]; other site
431946012337	G-X-G motif; other site
431946012338	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
431946012339	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946012340	active site
431946012341	intermolecular recognition site; other site
431946012342	dimerization interface [polypeptide binding]; other site
431946012343	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
431946012344	DNA binding site [nucleotide binding]
431946012345	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
431946012346	dimer interface [polypeptide binding]; other site
431946012347	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
431946012348	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
431946012349	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
431946012350	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
431946012351	active site
431946012352	ADP/pyrophosphate binding site [chemical binding]; other site
431946012353	dimerization interface [polypeptide binding]; other site
431946012354	allosteric effector site; other site
431946012355	fructose-1,6-bisphosphate binding site; other site
431946012356	sulfate transporter subunit; Provisional; Region: PRK10752
431946012357	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
431946012358	CDP-diacylglycerol pyrophosphatase, bacterial type; Region: cdh; TIGR00672
431946012359	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
431946012360	triosephosphate isomerase; Provisional; Region: PRK14567
431946012361	substrate binding site [chemical binding]; other site
431946012362	dimer interface [polypeptide binding]; other site
431946012363	catalytic triad [active]
431946012364	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
431946012365	Predicted membrane protein [Function unknown]; Region: COG3152
431946012366	hypothetical protein; Provisional; Region: PRK09981
431946012367	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
431946012368	Ligand Binding Site [chemical binding]; other site
431946012369	ferredoxin-NADP reductase; Provisional; Region: PRK10926
431946012370	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
431946012371	FAD binding pocket [chemical binding]; other site
431946012372	FAD binding motif [chemical binding]; other site
431946012373	phosphate binding motif [ion binding]; other site
431946012374	beta-alpha-beta structure motif; other site
431946012375	NAD binding pocket [chemical binding]; other site
431946012376	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
431946012377	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
431946012378	putative active site [active]
431946012379	glycerol kinase; Provisional; Region: glpK; PRK00047
431946012380	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
431946012381	N- and C-terminal domain interface [polypeptide binding]; other site
431946012382	active site
431946012383	MgATP binding site [chemical binding]; other site
431946012384	catalytic site [active]
431946012385	metal binding site [ion binding]; metal-binding site
431946012386	glycerol binding site [chemical binding]; other site
431946012387	homotetramer interface [polypeptide binding]; other site
431946012388	homodimer interface [polypeptide binding]; other site
431946012389	FBP binding site [chemical binding]; other site
431946012390	protein IIAGlc interface [polypeptide binding]; other site
431946012391	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
431946012392	amphipathic channel; other site
431946012393	Asn-Pro-Ala signature motifs; other site
431946012394	septal ring assembly protein ZapB; Provisional; Region: PRK15422
431946012395	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
431946012396	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Region: menA; TIGR00751
431946012397	UbiA prenyltransferase family; Region: UbiA; pfam01040
431946012398	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
431946012399	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946012400	Walker A motif; other site
431946012401	ATP binding site [chemical binding]; other site
431946012402	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
431946012403	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
431946012404	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
431946012405	active site
431946012406	HslU subunit interaction site [polypeptide binding]; other site
431946012407	essential cell division protein FtsN; Provisional; Region: PRK10927
431946012408	cell division protein FtsN; Provisional; Region: PRK12757
431946012409	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
431946012410	DNA binding site [nucleotide binding]
431946012411	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
431946012412	domain linker motif; other site
431946012413	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
431946012414	dimerization interface [polypeptide binding]; other site
431946012415	ligand binding site [chemical binding]; other site
431946012416	primosome assembly protein PriA; Validated; Region: PRK05580
431946012417	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
431946012418	ATP binding site [chemical binding]; other site
431946012419	putative Mg++ binding site [ion binding]; other site
431946012420	helicase superfamily c-terminal domain; Region: HELICc; smart00490
431946012421	ATP-binding site [chemical binding]; other site
431946012422	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
431946012423	hypothetical protein; Provisional; Region: PRK10030
431946012424	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
431946012425	dimerization interface [polypeptide binding]; other site
431946012426	DNA binding site [nucleotide binding]
431946012427	corepressor binding sites; other site
431946012428	cystathionine gamma-synthase; Provisional; Region: PRK08045
431946012429	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
431946012430	homodimer interface [polypeptide binding]; other site
431946012431	substrate-cofactor binding pocket; other site
431946012432	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946012433	catalytic residue [active]
431946012434	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
431946012435	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
431946012436	putative catalytic residues [active]
431946012437	putative nucleotide binding site [chemical binding]; other site
431946012438	putative aspartate binding site [chemical binding]; other site
431946012439	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
431946012440	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
431946012441	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
431946012442	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
431946012443	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
431946012444	active site
431946012445	metal binding site [ion binding]; metal-binding site
431946012446	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
431946012447	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
431946012448	FAD binding site [chemical binding]; other site
431946012449	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
431946012450	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
431946012451	heme binding site [chemical binding]; other site
431946012452	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
431946012453	EamA-like transporter family; Region: EamA; pfam00892
431946012454	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
431946012455	EamA-like transporter family; Region: EamA; pfam00892
431946012456	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3738
431946012457	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
431946012458	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
431946012459	dimer interface [polypeptide binding]; other site
431946012460	active site
431946012461	metal binding site [ion binding]; metal-binding site
431946012462	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
431946012463	active site
431946012464	intersubunit interactions; other site
431946012465	catalytic residue [active]
431946012466	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
431946012467	dimerization domain swap beta strand [polypeptide binding]; other site
431946012468	regulatory protein interface [polypeptide binding]; other site
431946012469	active site
431946012470	regulatory phosphorylation site [posttranslational modification]; other site
431946012471	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
431946012472	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
431946012473	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
431946012474	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
431946012475	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
431946012476	active site
431946012477	phosphorylation site [posttranslational modification]
431946012478	putative PTS system fructose-like transporter subunit EIIC; Provisional; Region: PRK10478
431946012479	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
431946012480	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
431946012481	active site
431946012482	P-loop; other site
431946012483	phosphorylation site [posttranslational modification]
431946012484	putative formate acetyltransferase 2; Provisional; Region: pflD; PRK09983
431946012485	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
431946012486	dimer interface [polypeptide binding]; other site
431946012487	active site
431946012488	glycine loop; other site
431946012489	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
431946012490	FeS/SAM binding site; other site
431946012491	pyruvate formate lyase II activase; Provisional; Region: PRK10076
431946012492	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
431946012493	active site
431946012494	P-loop; other site
431946012495	phosphorylation site [posttranslational modification]
431946012496	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
431946012497	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946012498	hypothetical protein; Provisional; Region: PRK10649
431946012499	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
431946012500	Sulfatase; Region: Sulfatase; pfam00884
431946012501	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
431946012502	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
431946012503	acetylornithine deacetylase; Provisional; Region: PRK05111
431946012504	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
431946012505	metal binding site [ion binding]; metal-binding site
431946012506	putative dimer interface [polypeptide binding]; other site
431946012507	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
431946012508	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
431946012509	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
431946012510	nucleotide binding site [chemical binding]; other site
431946012511	N-acetyl-L-glutamate binding site [chemical binding]; other site
431946012512	argininosuccinate lyase; Provisional; Region: PRK04833
431946012513	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
431946012514	active sites [active]
431946012515	tetramer interface [polypeptide binding]; other site
431946012516	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
431946012517	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946012518	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
431946012519	dimerization interface [polypeptide binding]; other site
431946012520	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
431946012521	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
431946012522	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
431946012523	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
431946012524	M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_like1; cd05666
431946012525	metal binding site [ion binding]; metal-binding site
431946012526	putative dimer interface [polypeptide binding]; other site
431946012527	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946012528	metabolite-proton symporter; Region: 2A0106; TIGR00883
431946012529	putative substrate translocation pore; other site
431946012530	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
431946012531	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
431946012532	hypothetical protein; Provisional; Region: PRK11056
431946012533	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
431946012534	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946012535	S-adenosylmethionine binding site [chemical binding]; other site
431946012536	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
431946012537	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
431946012538	N-terminal plug; other site
431946012539	ligand-binding site [chemical binding]; other site
431946012540	glutamate racemase; Provisional; Region: PRK00865
431946012541	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
431946012542	FAD binding domain; Region: FAD_binding_4; pfam01565
431946012543	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
431946012544	Biotin operon repressor [Transcription]; Region: BirA; COG1654
431946012545	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
431946012546	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
431946012547	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
431946012548	pantothenate kinase; Provisional; Region: PRK05439
431946012549	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
431946012550	ATP-binding site [chemical binding]; other site
431946012551	CoA-binding site [chemical binding]; other site
431946012552	Mg2+-binding site [ion binding]; other site
431946012553	elongation factor Tu; Reviewed; Region: PRK00049
431946012554	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
431946012555	G1 box; other site
431946012556	GEF interaction site [polypeptide binding]; other site
431946012557	GTP/Mg2+ binding site [chemical binding]; other site
431946012558	Switch I region; other site
431946012559	G2 box; other site
431946012560	G3 box; other site
431946012561	Switch II region; other site
431946012562	G4 box; other site
431946012563	G5 box; other site
431946012564	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
431946012565	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
431946012566	Antibiotic Binding Site [chemical binding]; other site
431946012567	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
431946012568	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
431946012569	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
431946012570	putative homodimer interface [polypeptide binding]; other site
431946012571	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
431946012572	heterodimer interface [polypeptide binding]; other site
431946012573	homodimer interface [polypeptide binding]; other site
431946012574	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
431946012575	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
431946012576	23S rRNA interface [nucleotide binding]; other site
431946012577	L7/L12 interface [polypeptide binding]; other site
431946012578	putative thiostrepton binding site; other site
431946012579	L25 interface [polypeptide binding]; other site
431946012580	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
431946012581	mRNA/rRNA interface [nucleotide binding]; other site
431946012582	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
431946012583	23S rRNA interface [nucleotide binding]; other site
431946012584	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
431946012585	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
431946012586	core dimer interface [polypeptide binding]; other site
431946012587	peripheral dimer interface [polypeptide binding]; other site
431946012588	L10 interface [polypeptide binding]; other site
431946012589	L11 interface [polypeptide binding]; other site
431946012590	putative EF-Tu interaction site [polypeptide binding]; other site
431946012591	putative EF-G interaction site [polypeptide binding]; other site
431946012592	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
431946012593	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
431946012594	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
431946012595	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
431946012596	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
431946012597	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
431946012598	RPB3 interaction site [polypeptide binding]; other site
431946012599	RPB1 interaction site [polypeptide binding]; other site
431946012600	RPB11 interaction site [polypeptide binding]; other site
431946012601	RPB10 interaction site [polypeptide binding]; other site
431946012602	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
431946012603	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
431946012604	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
431946012605	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
431946012606	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
431946012607	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
431946012608	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
431946012609	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
431946012610	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
431946012611	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
431946012612	DNA binding site [nucleotide binding]
431946012613	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
431946012614	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
431946012615	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
431946012616	FeS/SAM binding site; other site
431946012617	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
431946012618	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
431946012619	ThiS interaction site; other site
431946012620	putative active site [active]
431946012621	tetramer interface [polypeptide binding]; other site
431946012622	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
431946012623	thiS-thiF/thiG interaction site; other site
431946012624	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
431946012625	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
431946012626	ATP binding site [chemical binding]; other site
431946012627	substrate interface [chemical binding]; other site
431946012628	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
431946012629	thiamine phosphate binding site [chemical binding]; other site
431946012630	active site
431946012631	pyrophosphate binding site [ion binding]; other site
431946012632	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
431946012633	ThiC-associated domain; Region: ThiC-associated; pfam13667
431946012634	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
431946012635	Regulator of sigma D [Transcription]; Region: Rsd; COG3160
431946012636	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
431946012637	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
431946012638	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
431946012639	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
431946012640	putative NADH binding site [chemical binding]; other site
431946012641	putative active site [active]
431946012642	nudix motif; other site
431946012643	putative metal binding site [ion binding]; other site
431946012644	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
431946012645	substrate binding site [chemical binding]; other site
431946012646	active site
431946012647	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
431946012648	Active_site [active]
431946012649	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
431946012650	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
431946012651	IHF dimer interface [polypeptide binding]; other site
431946012652	IHF - DNA interface [nucleotide binding]; other site
431946012653	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
431946012654	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
431946012655	dimer interface [polypeptide binding]; other site
431946012656	sensor protein ZraS; Provisional; Region: PRK10364
431946012657	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
431946012658	dimer interface [polypeptide binding]; other site
431946012659	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946012660	ATP binding site [chemical binding]; other site
431946012661	Mg2+ binding site [ion binding]; other site
431946012662	G-X-G motif; other site
431946012663	transcriptional regulatory protein ZraR; Provisional; Region: PRK10365
431946012664	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946012665	active site
431946012666	phosphorylation site [posttranslational modification]
431946012667	intermolecular recognition site; other site
431946012668	dimerization interface [polypeptide binding]; other site
431946012669	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946012670	Walker A motif; other site
431946012671	ATP binding site [chemical binding]; other site
431946012672	Walker B motif; other site
431946012673	arginine finger; other site
431946012674	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
431946012675	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
431946012676	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
431946012677	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
431946012678	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
431946012679	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
431946012680	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
431946012681	purine monophosphate binding site [chemical binding]; other site
431946012682	dimer interface [polypeptide binding]; other site
431946012683	putative catalytic residues [active]
431946012684	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
431946012685	hypothetical protein; Provisional; Region: PRK10039
431946012686	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
431946012687	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
431946012688	Coenzyme A binding pocket [chemical binding]; other site
431946012689	homoserine O-succinyltransferase; Provisional; Region: PRK05368
431946012690	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
431946012691	proposed active site lysine [active]
431946012692	conserved cys residue [active]
431946012693	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
431946012694	malate synthase A; Region: malate_syn_A; TIGR01344
431946012695	active site
431946012696	isocitrate lyase; Provisional; Region: PRK15063
431946012697	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
431946012698	tetramer interface [polypeptide binding]; other site
431946012699	active site
431946012700	Mg2+/Mn2+ binding site [ion binding]; other site
431946012701	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
431946012702	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
431946012703	transcriptional repressor IclR; Provisional; Region: PRK11569
431946012704	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
431946012705	Bacterial transcriptional regulator; Region: IclR; pfam01614
431946012706	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
431946012707	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
431946012708	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
431946012709	substrate binding pocket [chemical binding]; other site
431946012710	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
431946012711	B12 binding site [chemical binding]; other site
431946012712	cobalt ligand [ion binding]; other site
431946012713	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
431946012714	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
431946012715	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
431946012716	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
431946012717	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
431946012718	active site pocket [active]
431946012719	oxyanion hole [active]
431946012720	catalytic triad [active]
431946012721	active site nucleophile [active]
431946012722	L-sorbose-1-phosphate reductase; Region: sorbose_phosphate_red; cd08238
431946012723	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
431946012724	putative NAD(P) binding site [chemical binding]; other site
431946012725	catalytic Zn binding site [ion binding]; other site
431946012726	PTS system, mannose/fructose/sorbose family, IID component; Region: EIID-AGA; TIGR00828
431946012727	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
431946012728	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
431946012729	active site
431946012730	phosphorylation site [posttranslational modification]
431946012731	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
431946012732	active pocket/dimerization site; other site
431946012733	active site
431946012734	phosphorylation site [posttranslational modification]
431946012735	sorbitol-6-phosphate 2-dehydrogenase; Provisional; Region: PRK06171
431946012736	classical (c) SDRs; Region: SDR_c; cd05233
431946012737	NAD(P) binding site [chemical binding]; other site
431946012738	active site
431946012739	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
431946012740	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
431946012741	putative DNA binding site [nucleotide binding]; other site
431946012742	putative Zn2+ binding site [ion binding]; other site
431946012743	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
431946012744	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
431946012745	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
431946012746	RNA binding surface [nucleotide binding]; other site
431946012747	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
431946012748	probable active site [active]
431946012749	hypothetical protein; Provisional; Region: PRK10515
431946012750	aspartate kinase III; Validated; Region: PRK09084
431946012751	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
431946012752	nucleotide binding site [chemical binding]; other site
431946012753	substrate binding site [chemical binding]; other site
431946012754	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_1; cd04932
431946012755	lysine allosteric regulatory site; other site
431946012756	dimer interface [polypeptide binding]; other site
431946012757	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
431946012758	dimer interface [polypeptide binding]; other site
431946012759	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
431946012760	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
431946012761	active site
431946012762	dimer interface [polypeptide binding]; other site
431946012763	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
431946012764	dimer interface [polypeptide binding]; other site
431946012765	active site
431946012766	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
431946012767	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
431946012768	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
431946012769	phosphate-starvation-inducible protein PsiE; Provisional; Region: PRK02833
431946012770	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
431946012771	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946012772	dimer interface [polypeptide binding]; other site
431946012773	conserved gate region; other site
431946012774	putative PBP binding loops; other site
431946012775	ABC-ATPase subunit interface; other site
431946012776	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946012777	dimer interface [polypeptide binding]; other site
431946012778	conserved gate region; other site
431946012779	putative PBP binding loops; other site
431946012780	ABC-ATPase subunit interface; other site
431946012781	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
431946012782	Domain of unknown function (DUF4179); Region: DUF4179; pfam13786
431946012783	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
431946012784	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
431946012785	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
431946012786	Walker A/P-loop; other site
431946012787	ATP binding site [chemical binding]; other site
431946012788	Q-loop/lid; other site
431946012789	ABC transporter signature motif; other site
431946012790	Walker B; other site
431946012791	D-loop; other site
431946012792	H-loop/switch region; other site
431946012793	TOBE domain; Region: TOBE_2; pfam08402
431946012794	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
431946012795	trimer interface; other site
431946012796	sugar binding site [chemical binding]; other site
431946012797	maltose regulon periplasmic protein; Provisional; Region: PRK10564
431946012798	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
431946012799	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
431946012800	UbiA prenyltransferase family; Region: UbiA; pfam01040
431946012801	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
431946012802	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
431946012803	putative acyl-acceptor binding pocket; other site
431946012804	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
431946012805	LexA repressor; Validated; Region: PRK00215
431946012806	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
431946012807	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
431946012808	Catalytic site [active]
431946012809	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
431946012810	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
431946012811	hypothetical protein; Provisional; Region: PRK10428
431946012812	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
431946012813	metal binding site 2 [ion binding]; metal-binding site
431946012814	putative DNA binding helix; other site
431946012815	metal binding site 1 [ion binding]; metal-binding site
431946012816	dimer interface [polypeptide binding]; other site
431946012817	structural Zn2+ binding site [ion binding]; other site
431946012818	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
431946012819	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
431946012820	FMN binding site [chemical binding]; other site
431946012821	active site
431946012822	catalytic residues [active]
431946012823	substrate binding site [chemical binding]; other site
431946012824	phage shock protein G; Reviewed; Region: pspG; PRK09459
431946012825	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
431946012826	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
431946012827	NADP binding site [chemical binding]; other site
431946012828	dimer interface [polypeptide binding]; other site
431946012829	L-aspartate oxidase; Provisional; Region: PRK06175
431946012830	FAD binding domain; Region: FAD_binding_2; pfam00890
431946012831	Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; COG1914
431946012832	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
431946012833	3-hydroxybutyryl-CoA dehydratase; Validated; Region: PRK05809
431946012834	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
431946012835	substrate binding site [chemical binding]; other site
431946012836	oxyanion hole (OAH) forming residues; other site
431946012837	trimer interface [polypeptide binding]; other site
431946012838	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
431946012839	Coenzyme A transferase; Region: CoA_trans; smart00882
431946012840	Coenzyme A transferase; Region: CoA_trans; cl17247
431946012841	Transcriptional regulators [Transcription]; Region: PurR; COG1609
431946012842	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
431946012843	DNA binding site [nucleotide binding]
431946012844	domain linker motif; other site
431946012845	Ligand-binding domain of MalI, a transcription regulator of the maltose system of Escherichia coli and its close homologs from other bacteria; Region: PBP1_MalI_like; cd06289
431946012846	putative dimerization interface [polypeptide binding]; other site
431946012847	putative ligand binding site [chemical binding]; other site
431946012848	replicative DNA helicase; Provisional; Region: PRK08006
431946012849	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
431946012850	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
431946012851	Walker A motif; other site
431946012852	ATP binding site [chemical binding]; other site
431946012853	Walker B motif; other site
431946012854	DNA binding loops [nucleotide binding]
431946012855	alanine racemase; Reviewed; Region: alr; PRK00053
431946012856	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
431946012857	active site
431946012858	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
431946012859	substrate binding site [chemical binding]; other site
431946012860	catalytic residues [active]
431946012861	dimer interface [polypeptide binding]; other site
431946012862	Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973
431946012863	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
431946012864	active site
431946012865	nucleotide binding site [chemical binding]; other site
431946012866	HIGH motif; other site
431946012867	KMSKS motif; other site
431946012868	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
431946012869	AAA domain; Region: AAA_28; pfam13521
431946012870	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
431946012871	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
431946012872	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946012873	homodimer interface [polypeptide binding]; other site
431946012874	catalytic residue [active]
431946012875	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
431946012876	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
431946012877	TPP-binding site [chemical binding]; other site
431946012878	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
431946012879	dimer interface [polypeptide binding]; other site
431946012880	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
431946012881	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
431946012882	E3 interaction surface; other site
431946012883	lipoyl attachment site [posttranslational modification]; other site
431946012884	e3 binding domain; Region: E3_binding; pfam02817
431946012885	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
431946012886	dihydrolipoamide dehydrogenase; Validated; Region: PRK06327
431946012887	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
431946012888	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
431946012889	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
431946012890	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
431946012891	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
431946012892	CoA-ligase; Region: Ligase_CoA; pfam00549
431946012893	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
431946012894	CoA binding domain; Region: CoA_binding; smart00881
431946012895	CoA-ligase; Region: Ligase_CoA; pfam00549
431946012896	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
431946012897	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
431946012898	transmembrane helices; other site
431946012899	Malate/L-lactate dehydrogenase; Region: Ldh_2; cl00900
431946012900	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
431946012901	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946012902	active site
431946012903	phosphorylation site [posttranslational modification]
431946012904	intermolecular recognition site; other site
431946012905	dimerization interface [polypeptide binding]; other site
431946012906	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946012907	Walker A motif; other site
431946012908	ATP binding site [chemical binding]; other site
431946012909	Walker B motif; other site
431946012910	arginine finger; other site
431946012911	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
431946012912	Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms]; Region: COG4191
431946012913	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
431946012914	dimer interface [polypeptide binding]; other site
431946012915	phosphorylation site [posttranslational modification]
431946012916	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946012917	ATP binding site [chemical binding]; other site
431946012918	Mg2+ binding site [ion binding]; other site
431946012919	G-X-G motif; other site
431946012920	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
431946012921	active site
431946012922	motif I; other site
431946012923	motif II; other site
431946012924	Uncharacterized protein family UPF0047; Region: UPF0047; cl00439
431946012925	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
431946012926	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
431946012927	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
431946012928	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
431946012929	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
431946012930	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
431946012931	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
431946012932	dimer interface [polypeptide binding]; other site
431946012933	ssDNA binding site [nucleotide binding]; other site
431946012934	tetramer (dimer of dimers) interface [polypeptide binding]; other site
431946012935	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
431946012936	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
431946012937	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
431946012938	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
431946012939	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
431946012940	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946012941	redox-sensitivie transcriptional activator SoxR; Provisional; Region: PRK15002
431946012942	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
431946012943	DNA binding residues [nucleotide binding]
431946012944	dimer interface [polypeptide binding]; other site
431946012945	[2Fe-2S] cluster binding site [ion binding]; other site
431946012946	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
431946012947	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
431946012948	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
431946012949	Transcriptional regulator [Transcription]; Region: LysR; COG0583
431946012950	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946012951	The C-terminal substrate binding domain of LysR-like transcriptional regulator CidR, contains the type 2 periplasmic binding fold; Region: PBP2_CidR; cd08438
431946012952	putative dimerization interface [polypeptide binding]; other site
431946012953	Putative effector of murein hydrolase LrgA [General function prediction only]; Region: COG1380
431946012954	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
431946012955	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
431946012956	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
431946012957	Na binding site [ion binding]; other site
431946012958	Predicted membrane protein [Function unknown]; Region: COG3162
431946012959	acetyl-CoA synthetase; Provisional; Region: PRK00174
431946012960	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
431946012961	active site
431946012962	CoA binding site [chemical binding]; other site
431946012963	acyl-activating enzyme (AAE) consensus motif; other site
431946012964	AMP binding site [chemical binding]; other site
431946012965	acetate binding site [chemical binding]; other site
431946012966	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
431946012967	cytochrome c nitrite reductase pentaheme subunit; Provisional; Region: PRK11659
431946012968	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
431946012969	Formate-dependent nitrite reductase, membrane component [Inorganic ion transport and metabolism]; Region: NrfD; COG3301
431946012970	cytochrome c nitrite reductase, NrfD subunit; Region: cyt_nit_nrfD; TIGR03148
431946012971	heme lyase subunit NrfE; Provisional; Region: PRK10369
431946012972	formate-dependent nitrite reductase complex subunit NrfF; Provisional; Region: PRK10144
431946012973	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
431946012974	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
431946012975	binding surface
431946012976	TPR motif; other site
431946012977	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
431946012978	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
431946012979	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
431946012980	Sel1-like repeats; Region: SEL1; smart00671
431946012981	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
431946012982	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
431946012983	Walker A/P-loop; other site
431946012984	ATP binding site [chemical binding]; other site
431946012985	Q-loop/lid; other site
431946012986	ABC transporter signature motif; other site
431946012987	Walker B; other site
431946012988	D-loop; other site
431946012989	H-loop/switch region; other site
431946012990	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
431946012991	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
431946012992	Walker A/P-loop; other site
431946012993	ATP binding site [chemical binding]; other site
431946012994	Q-loop/lid; other site
431946012995	ABC transporter signature motif; other site
431946012996	Walker B; other site
431946012997	D-loop; other site
431946012998	H-loop/switch region; other site
431946012999	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
431946013000	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
431946013001	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946013002	dimer interface [polypeptide binding]; other site
431946013003	conserved gate region; other site
431946013004	ABC-ATPase subunit interface; other site
431946013005	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
431946013006	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946013007	dimer interface [polypeptide binding]; other site
431946013008	conserved gate region; other site
431946013009	putative PBP binding loops; other site
431946013010	ABC-ATPase subunit interface; other site
431946013011	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
431946013012	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512
431946013013	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
431946013014	molybdopterin cofactor binding site; other site
431946013015	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
431946013016	molybdopterin cofactor binding site; other site
431946013017	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
431946013018	putative outer membrane efflux protein MdtP; Provisional; Region: PRK09915
431946013019	multidrug efflux system protein MdtO; Provisional; Region: PRK11427
431946013020	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
431946013021	multidrug resistance protein MdtN; Provisional; Region: PRK10476
431946013022	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
431946013023	HlyD family secretion protein; Region: HlyD_3; pfam13437
431946013024	Alkyl sulfatase and related hydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2015
431946013025	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
431946013026	D-allose kinase; Provisional; Region: PRK09698
431946013027	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
431946013028	nucleotide binding site [chemical binding]; other site
431946013029	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
431946013030	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
431946013031	substrate binding site [chemical binding]; other site
431946013032	hexamer interface [polypeptide binding]; other site
431946013033	metal binding site [ion binding]; metal-binding site
431946013034	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
431946013035	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
431946013036	TM-ABC transporter signature motif; other site
431946013037	D-allose transporter ATP-binding protein; Provisional; Region: PRK09700
431946013038	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
431946013039	Walker A/P-loop; other site
431946013040	ATP binding site [chemical binding]; other site
431946013041	Q-loop/lid; other site
431946013042	ABC transporter signature motif; other site
431946013043	Walker B; other site
431946013044	D-loop; other site
431946013045	H-loop/switch region; other site
431946013046	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
431946013047	D-allose transporter subunit; Provisional; Region: PRK09701
431946013048	Periplasmic allose-binding domain of bacterial transport systems that function as a primary receptor of active transport and chemotaxis; Region: PBP1_allose_binding; cd06320
431946013049	ligand binding site [chemical binding]; other site
431946013050	dimerization interface [polypeptide binding]; other site
431946013051	zinc binding site [ion binding]; other site
431946013052	DNA-binding transcriptional repressor RpiR; Provisional; Region: PRK11337
431946013053	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
431946013054	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
431946013055	putative active site [active]
431946013056	ribose 5-phosphate isomerase B; Region: rpiB; TIGR01120
431946013057	putative hydrolase; Provisional; Region: PRK02113
431946013058	carbon-phosphorus lyase complex accessory protein; Provisional; Region: phnP; PRK11244
431946013059	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
431946013060	Coenzyme A binding pocket [chemical binding]; other site
431946013061	ribose 1,5-bisphosphokinase; Provisional; Region: PRK10078
431946013062	Guanylate kinase; Region: Guanylate_kin; pfam00625
431946013063	active site
431946013064	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
431946013065	Metal-dependent hydrolase involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: COG3454
431946013066	PhnM is believed to be a subunit of the membrane associated C-P lyase complex. C-P lyase is thought to catalyze the direct cleavage of inactivated C-P bonds to yield inorganic phosphate and the corresponding hydrocarbons. It is responsible for cleavage...; Region: PhnM; cd01306
431946013067	active site
431946013068	ABC-type phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PhnL; COG4778
431946013069	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
431946013070	Walker A/P-loop; other site
431946013071	ATP binding site [chemical binding]; other site
431946013072	Q-loop/lid; other site
431946013073	ABC transporter signature motif; other site
431946013074	Walker B; other site
431946013075	D-loop; other site
431946013076	H-loop/switch region; other site
431946013077	phosphonate C-P lyase system protein PhnK; Provisional; Region: phnK; PRK11701
431946013078	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
431946013079	Walker A/P-loop; other site
431946013080	ATP binding site [chemical binding]; other site
431946013081	Q-loop/lid; other site
431946013082	ABC transporter signature motif; other site
431946013083	Walker B; other site
431946013084	D-loop; other site
431946013085	H-loop/switch region; other site
431946013086	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
431946013087	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnJ; COG3627
431946013088	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnI; COG3626
431946013089	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnH; COG3625
431946013090	Phosphonate metabolism protein PhnG; Region: PhnG; pfam06754
431946013091	phosphonate metabolism transcriptional regulator PhnF; Provisional; Region: PRK10079
431946013092	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
431946013093	DNA-binding site [nucleotide binding]; DNA binding site
431946013094	UTRA domain; Region: UTRA; pfam07702
431946013095	ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism]; Region: COG3639
431946013096	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
431946013097	dimer interface [polypeptide binding]; other site
431946013098	conserved gate region; other site
431946013099	putative PBP binding loops; other site
431946013100	ABC-ATPase subunit interface; other site
431946013101	phosphonate ABC transporter, periplasmic phosphonate binding protein; Region: PhnD; TIGR03431
431946013102	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
431946013103	substrate binding pocket [chemical binding]; other site
431946013104	membrane-bound complex binding site; other site
431946013105	hinge residues; other site
431946013106	phosphonate/organophosphate ester transporter subunit; Provisional; Region: PRK09984
431946013107	ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Region: ABC_PhnC_transporter; cd03256
431946013108	Walker A/P-loop; other site
431946013109	ATP binding site [chemical binding]; other site
431946013110	Q-loop/lid; other site
431946013111	ABC transporter signature motif; other site
431946013112	Walker B; other site
431946013113	D-loop; other site
431946013114	H-loop/switch region; other site
431946013115	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
431946013116	dimer interface [polypeptide binding]; other site
431946013117	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
431946013118	hypothetical protein; Provisional; Region: PRK10220
431946013119	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
431946013120	PhnA protein; Region: PhnA; pfam03831
431946013121	hypothetical protein; Provisional; Region: PRK09866
431946013122	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
431946013123	G1 box; other site
431946013124	GTP/Mg2+ binding site [chemical binding]; other site
431946013125	G2 box; other site
431946013126	Switch I region; other site
431946013127	G3 box; other site
431946013128	Switch II region; other site
431946013129	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
431946013130	G2 box; other site
431946013131	Switch I region; other site
431946013132	G3 box; other site
431946013133	Switch II region; other site
431946013134	G4 box; other site
431946013135	G5 box; other site
431946013136	YjcZ-like protein; Region: YjcZ; pfam13990
431946013137	proline/glycine betaine transporter; Provisional; Region: PRK10642
431946013138	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946013139	putative substrate translocation pore; other site
431946013140	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
431946013141	sensor protein BasS/PmrB; Provisional; Region: PRK10755
431946013142	HAMP domain; Region: HAMP; pfam00672
431946013143	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
431946013144	dimer interface [polypeptide binding]; other site
431946013145	phosphorylation site [posttranslational modification]
431946013146	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946013147	ATP binding site [chemical binding]; other site
431946013148	Mg2+ binding site [ion binding]; other site
431946013149	G-X-G motif; other site
431946013150	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
431946013151	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946013152	active site
431946013153	phosphorylation site [posttranslational modification]
431946013154	intermolecular recognition site; other site
431946013155	dimerization interface [polypeptide binding]; other site
431946013156	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
431946013157	DNA binding site [nucleotide binding]
431946013158	putative metal dependent hydrolase; Provisional; Region: PRK11598
431946013159	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
431946013160	Sulfatase; Region: Sulfatase; pfam00884
431946013161	arginine:agmatin antiporter; Provisional; Region: PRK10644
431946013162	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
431946013163	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946013164	arginine decarboxylase; Provisional; Region: PRK15029
431946013165	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
431946013166	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
431946013167	homodimer interface [polypeptide binding]; other site
431946013168	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946013169	catalytic residue [active]
431946013170	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
431946013171	DNA-binding transcriptional regulator MelR; Provisional; Region: PRK10371
431946013172	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946013173	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946013174	alpha-galactosidase; Provisional; Region: PRK15076
431946013175	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
431946013176	NAD binding site [chemical binding]; other site
431946013177	sugar binding site [chemical binding]; other site
431946013178	divalent metal binding site [ion binding]; other site
431946013179	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
431946013180	dimer interface [polypeptide binding]; other site
431946013181	hypothetical protein; Provisional; Region: PRK09867
431946013182	fumarate hydratase; Provisional; Region: PRK15389
431946013183	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
431946013184	Fumarase C-terminus; Region: Fumerase_C; pfam05683
431946013185	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
431946013186	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
431946013187	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
431946013188	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946013189	active site
431946013190	phosphorylation site [posttranslational modification]
431946013191	intermolecular recognition site; other site
431946013192	dimerization interface [polypeptide binding]; other site
431946013193	Transcriptional regulator; Region: CitT; pfam12431
431946013194	sensory histidine kinase DcuS; Provisional; Region: PRK11086
431946013195	PAS domain; Region: PAS; smart00091
431946013196	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946013197	ATP binding site [chemical binding]; other site
431946013198	Mg2+ binding site [ion binding]; other site
431946013199	G-X-G motif; other site
431946013200	Uncharacterized conserved protein [Function unknown]; Region: COG3592
431946013201	Predicted acetyltransferase [General function prediction only]; Region: COG2388
431946013202	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
431946013203	PapC N-terminal domain; Region: PapC_N; pfam13954
431946013204	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
431946013205	PapC C-terminal domain; Region: PapC_C; pfam13953
431946013206	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
431946013207	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
431946013208	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
431946013209	Immunoglobulin A1 protease; Region: Peptidase_S6; pfam02395
431946013210	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cl00185
431946013211	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
431946013212	Autotransporter beta-domain; Region: Autotransporter; pfam03797
431946013213	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
431946013214	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946013215	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
431946013216	Immunoglobulin A1 protease; Region: Peptidase_S6; pfam02395
431946013217	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
431946013218	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
431946013219	Autotransporter beta-domain; Region: Autotransporter; pfam03797
431946013220	Predicted acetyltransferase [General function prediction only]; Region: COG2388
431946013221	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
431946013222	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
431946013223	lysyl-tRNA synthetase; Reviewed; Region: PRK12445
431946013224	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
431946013225	dimer interface [polypeptide binding]; other site
431946013226	putative anticodon binding site; other site
431946013227	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
431946013228	motif 1; other site
431946013229	active site
431946013230	motif 2; other site
431946013231	motif 3; other site
431946013232	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
431946013233	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946013234	putative substrate translocation pore; other site
431946013235	POT family; Region: PTR2; pfam00854
431946013236	lysine decarboxylase CadA; Provisional; Region: PRK15400
431946013237	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
431946013238	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
431946013239	homodimer interface [polypeptide binding]; other site
431946013240	pyridoxal 5'-phosphate binding site [chemical binding]; other site
431946013241	catalytic residue [active]
431946013242	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
431946013243	lysine/cadaverine antiporter; Provisional; Region: cadB; PRK10435
431946013244	DNA-binding transcriptional activator CadC; Provisional; Region: PRK10153
431946013245	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
431946013246	DNA binding site [nucleotide binding]
431946013247	putative transcriptional regulator; Provisional; Region: PRK11640
431946013248	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
431946013249	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
431946013250	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
431946013251	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
431946013252	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
431946013253	DsbD alpha interface [polypeptide binding]; other site
431946013254	catalytic residues [active]
431946013255	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
431946013256	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
431946013257	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
431946013258	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
431946013259	Aspartase; Region: Aspartase; cd01357
431946013260	active sites [active]
431946013261	tetramer interface [polypeptide binding]; other site
431946013262	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
431946013263	putative transporter; Provisional; Region: PRK11021
431946013264	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
431946013265	oligomerisation interface [polypeptide binding]; other site
431946013266	mobile loop; other site
431946013267	roof hairpin; other site
431946013268	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
431946013269	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
431946013270	ring oligomerisation interface [polypeptide binding]; other site
431946013271	ATP/Mg binding site [chemical binding]; other site
431946013272	stacking interactions; other site
431946013273	hinge regions; other site
431946013274	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
431946013275	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
431946013276	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
431946013277	FeS/SAM binding site; other site
431946013278	elongation factor P; Validated; Region: PRK00529
431946013279	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
431946013280	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
431946013281	RNA binding site [nucleotide binding]; other site
431946013282	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
431946013283	RNA binding site [nucleotide binding]; other site
431946013284	entericidin A; Provisional; Region: PRK09810
431946013285	entericidin B membrane lipoprotein; Provisional; Region: PRK10081
431946013286	multidrug efflux system protein; Provisional; Region: PRK11431
431946013287	Bacterial lipocalin [Cell envelope biogenesis, outer membrane]; Region: Blc; COG3040
431946013288	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
431946013289	beta-lactamase/D-alanine carboxypeptidase; Provisional; Region: ampC; PRK11289
431946013290	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
431946013291	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
431946013292	Iron-sulfur protein interface; other site
431946013293	proximal quinone binding site [chemical binding]; other site
431946013294	C-subunit interface; other site
431946013295	distal quinone binding site; other site
431946013296	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
431946013297	D-subunit interface [polypeptide binding]; other site
431946013298	Iron-sulfur protein interface; other site
431946013299	proximal quinone binding site [chemical binding]; other site
431946013300	distal quinone binding site [chemical binding]; other site
431946013301	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
431946013302	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
431946013303	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
431946013304	L-aspartate oxidase; Provisional; Region: PRK06175
431946013305	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
431946013306	poxB regulator PoxA; Provisional; Region: PRK09350
431946013307	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
431946013308	motif 1; other site
431946013309	dimer interface [polypeptide binding]; other site
431946013310	active site
431946013311	motif 2; other site
431946013312	motif 3; other site
431946013313	inner membrane transporter YjeM; Provisional; Region: PRK15238
431946013314	Protein of unknown function (DUF2645); Region: DUF2645; pfam10840
431946013315	putative mechanosensitive channel protein; Provisional; Region: PRK10929
431946013316	linker histone 1 and histone 5 domains; the basic subunit of chromatin is the nucleosome, consisting of an octamer of core histones, two full turns of DNA, a linker histone (H1 or H5) and a variable length of linker DNA; H1/H5 are chromatin-associated...; Region: H15; cl00073
431946013317	DNA-binding site [nucleotide binding]; DNA binding site
431946013318	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
431946013319	Mechanosensitive ion channel; Region: MS_channel; pfam00924
431946013320	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
431946013321	GTPase RsgA; Reviewed; Region: PRK12288
431946013322	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
431946013323	RNA binding site [nucleotide binding]; other site
431946013324	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
431946013325	GTPase/Zn-binding domain interface [polypeptide binding]; other site
431946013326	GTP/Mg2+ binding site [chemical binding]; other site
431946013327	G4 box; other site
431946013328	G5 box; other site
431946013329	G1 box; other site
431946013330	Switch I region; other site
431946013331	G2 box; other site
431946013332	G3 box; other site
431946013333	Switch II region; other site
431946013334	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
431946013335	catalytic site [active]
431946013336	putative active site [active]
431946013337	putative substrate binding site [chemical binding]; other site
431946013338	dimer interface [polypeptide binding]; other site
431946013339	epoxyqueuosine reductase; Region: TIGR00276
431946013340	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
431946013341	putative carbohydrate kinase; Provisional; Region: PRK10565
431946013342	yjeF N-terminal region; Region: yjeF_nterm; TIGR00197
431946013343	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
431946013344	putative substrate binding site [chemical binding]; other site
431946013345	putative ATP binding site [chemical binding]; other site
431946013346	ADP-binding protein; Provisional; Region: PRK10646
431946013347	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
431946013348	AMIN domain; Region: AMIN; pfam11741
431946013349	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
431946013350	active site
431946013351	metal binding site [ion binding]; metal-binding site
431946013352	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
431946013353	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946013354	ATP binding site [chemical binding]; other site
431946013355	Mg2+ binding site [ion binding]; other site
431946013356	G-X-G motif; other site
431946013357	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
431946013358	ATP binding site [chemical binding]; other site
431946013359	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
431946013360	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
431946013361	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
431946013362	bacterial Hfq-like; Region: Hfq; cd01716
431946013363	hexamer interface [polypeptide binding]; other site
431946013364	Sm1 motif; other site
431946013365	RNA binding site [nucleotide binding]; other site
431946013366	Sm2 motif; other site
431946013367	GTPase HflX; Provisional; Region: PRK11058
431946013368	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
431946013369	HflX GTPase family; Region: HflX; cd01878
431946013370	G1 box; other site
431946013371	GTP/Mg2+ binding site [chemical binding]; other site
431946013372	Switch I region; other site
431946013373	G2 box; other site
431946013374	G3 box; other site
431946013375	Switch II region; other site
431946013376	G4 box; other site
431946013377	G5 box; other site
431946013378	FtsH protease regulator HflK; Provisional; Region: PRK10930
431946013379	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
431946013380	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
431946013381	FtsH protease regulator HflC; Provisional; Region: PRK11029
431946013382	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
431946013383	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3242
431946013384	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
431946013385	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
431946013386	GDP-binding site [chemical binding]; other site
431946013387	ACT binding site; other site
431946013388	IMP binding site; other site
431946013389	Predicted transcriptional regulator [Transcription]; Region: COG1959
431946013390	transcriptional repressor NsrR; Provisional; Region: PRK11014
431946013391	exoribonuclease R; Provisional; Region: PRK11642
431946013392	Ribonuclease R winged-helix domain; Region: HTH_12; pfam08461
431946013393	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
431946013394	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
431946013395	RNB domain; Region: RNB; pfam00773
431946013396	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
431946013397	RNA binding site [nucleotide binding]; other site
431946013398	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
431946013399	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
431946013400	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
431946013401	Uncharacterized protein conserved in bacteria (DUF2170); Region: DUF2170; cl01551
431946013402	PspA/IM30 family; Region: PspA_IM30; pfam04012
431946013403	Protein of unknown function (DUF2491); Region: DUF2491; pfam10679
431946013404	Predicted membrane protein [Function unknown]; Region: COG3766
431946013405	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
431946013406	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
431946013407	Predicted integral membrane protein [Function unknown]; Region: COG5463
431946013408	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
431946013409	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
431946013410	Proteins involved in DNA damage response, similar to the AidB gene product; Region: AidB; cd01154
431946013411	FAD binding site [chemical binding]; other site
431946013412	substrate binding site [chemical binding]; other site
431946013413	catalytic residues [active]
431946013414	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
431946013415	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
431946013416	esterase; Provisional; Region: PRK10566
431946013417	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
431946013418	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
431946013419	transcriptional repressor UlaR; Provisional; Region: PRK13509
431946013420	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
431946013421	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
431946013422	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
431946013423	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
431946013424	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
431946013425	PTS system ascorbate-specific transporter subunits IICB; Provisional; Region: PRK09548
431946013426	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
431946013427	active site
431946013428	P-loop; other site
431946013429	phosphorylation site [posttranslational modification]
431946013430	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
431946013431	active site
431946013432	phosphorylation site [posttranslational modification]
431946013433	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
431946013434	active site
431946013435	dimer interface [polypeptide binding]; other site
431946013436	magnesium binding site [ion binding]; other site
431946013437	L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13209
431946013438	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
431946013439	AP (apurinic/apyrimidinic) site pocket; other site
431946013440	DNA interaction; other site
431946013441	Metal-binding active site; metal-binding site
431946013442	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
431946013443	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
431946013444	intersubunit interface [polypeptide binding]; other site
431946013445	active site
431946013446	Zn2+ binding site [ion binding]; other site
431946013447	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
431946013448	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
431946013449	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
431946013450	dimer interface [polypeptide binding]; other site
431946013451	ssDNA binding site [nucleotide binding]; other site
431946013452	tetramer (dimer of dimers) interface [polypeptide binding]; other site
431946013453	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
431946013454	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
431946013455	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
431946013456	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
431946013457	Helix-turn-helix domain; Region: HTH_31; pfam13560
431946013458	sequence-specific DNA binding site [nucleotide binding]; other site
431946013459	salt bridge; other site
431946013460	HipA-like N-terminal domain; Region: HipA_N; pfam07805
431946013461	HipA-like C-terminal domain; Region: HipA_C; pfam07804
431946013462	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946013463	D-galactonate transporter; Region: 2A0114; TIGR00893
431946013464	putative substrate translocation pore; other site
431946013465	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Region: SdhA; COG1053
431946013466	L-aspartate oxidase; Provisional; Region: PRK06175
431946013467	L-aspartate oxidase; Provisional; Region: PRK06175
431946013468	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
431946013469	Coenzyme A transferase; Region: CoA_trans; smart00882
431946013470	Coenzyme A transferase; Region: CoA_trans; cl17247
431946013471	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
431946013472	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
431946013473	substrate binding site [chemical binding]; other site
431946013474	oxyanion hole (OAH) forming residues; other site
431946013475	trimer interface [polypeptide binding]; other site
431946013476	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
431946013477	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: PRK12745
431946013478	putative beta-ketoacyl acyl carrier protein [ACP] reductase (BKR), subgroup 1, classical (c) SDR; Region: BKR_1_SDR_c; cd05337
431946013479	putative NAD(P) binding site [chemical binding]; other site
431946013480	active site
431946013481	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
431946013482	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
431946013483	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
431946013484	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
431946013485	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
431946013486	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
431946013487	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
431946013488	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
431946013489	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
431946013490	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
431946013491	Hemerythrin-like domain; Region: Hr-like; cd12108
431946013492	Fe binding site [ion binding]; other site
431946013493	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
431946013494	EamA-like transporter family; Region: EamA; pfam00892
431946013495	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
431946013496	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
431946013497	NADP binding site [chemical binding]; other site
431946013498	Predicted transcriptional regulators [Transcription]; Region: COG1733
431946013499	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
431946013500	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
431946013501	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
431946013502	active site
431946013503	metal binding site [ion binding]; metal-binding site
431946013504	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
431946013505	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
431946013506	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
431946013507	active site
431946013508	Predicted transcriptional regulator [General function prediction only]; Region: COG3054
431946013509	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
431946013510	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
431946013511	Domain of unknown function DUF21; Region: DUF21; pfam01595
431946013512	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
431946013513	Transporter associated domain; Region: CorC_HlyC; smart01091
431946013514	methionine sulfoxide reductase A; Provisional; Region: PRK00058
431946013515	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
431946013516	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
431946013517	Surface antigen; Region: Bac_surface_Ag; pfam01103
431946013518	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
431946013519	Family of unknown function (DUF490); Region: DUF490; pfam04357
431946013520	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
431946013521	putative active site pocket [active]
431946013522	dimerization interface [polypeptide binding]; other site
431946013523	putative catalytic residue [active]
431946013524	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
431946013525	dimer interface [polypeptide binding]; other site
431946013526	substrate binding site [chemical binding]; other site
431946013527	metal binding sites [ion binding]; metal-binding site
431946013528	Periplasmic binding domain of ABC-type YtfQ-like transport systems; Region: PBP1_YtfQ_like; cd06309
431946013529	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
431946013530	putative ligand binding site [chemical binding]; other site
431946013531	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
431946013532	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
431946013533	Walker A/P-loop; other site
431946013534	ATP binding site [chemical binding]; other site
431946013535	Q-loop/lid; other site
431946013536	ABC transporter signature motif; other site
431946013537	Walker B; other site
431946013538	D-loop; other site
431946013539	H-loop/switch region; other site
431946013540	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
431946013541	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
431946013542	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
431946013543	TM-ABC transporter signature motif; other site
431946013544	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
431946013545	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
431946013546	TM-ABC transporter signature motif; other site
431946013547	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
431946013548	AMP binding site [chemical binding]; other site
431946013549	metal binding site [ion binding]; metal-binding site
431946013550	active site
431946013551	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
431946013552	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
431946013553	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
431946013554	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
431946013555	hypothetical protein; Provisional; Region: PRK05255
431946013556	peptidase PmbA; Provisional; Region: PRK11040
431946013557	cytochrome b562; Provisional; Region: PRK15058
431946013558	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
431946013559	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
431946013560	FeS/SAM binding site; other site
431946013561	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
431946013562	ATP cone domain; Region: ATP-cone; pfam03477
431946013563	Class III ribonucleotide reductase; Region: RNR_III; cd01675
431946013564	effector binding site; other site
431946013565	active site
431946013566	Zn binding site [ion binding]; other site
431946013567	glycine loop; other site
431946013568	trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933
431946013569	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
431946013570	Ca binding site [ion binding]; other site
431946013571	active site
431946013572	catalytic site [active]
431946013573	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
431946013574	PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional; Region: PRK11007
431946013575	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
431946013576	active site turn [active]
431946013577	phosphorylation site [posttranslational modification]
431946013578	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
431946013579	trehalose repressor; Provisional; Region: treR; PRK09492
431946013580	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
431946013581	DNA binding site [nucleotide binding]
431946013582	domain linker motif; other site
431946013583	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
431946013584	dimerization interface [polypeptide binding]; other site
431946013585	ligand binding site [chemical binding]; other site
431946013586	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
431946013587	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
431946013588	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
431946013589	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
431946013590	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
431946013591	motif II; other site
431946013592	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
431946013593	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
431946013594	homotrimer interaction site [polypeptide binding]; other site
431946013595	putative active site [active]
431946013596	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
431946013597	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
431946013598	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
431946013599	aspartate carbamoyltransferase; Region: asp_carb_tr; TIGR00670
431946013600	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
431946013601	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
431946013602	PyrBI operon leader peptide; Region: PyrBI_leader; pfam08052
431946013603	Arginine repressor [Transcription]; Region: ArgR; COG1438
431946013604	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
431946013605	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
431946013606	Predicted membrane protein [Function unknown]; Region: COG1288
431946013607	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
431946013608	ornithine carbamoyltransferase; Validated; Region: PRK02102
431946013609	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
431946013610	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
431946013611	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
431946013612	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
431946013613	putative substrate binding site [chemical binding]; other site
431946013614	nucleotide binding site [chemical binding]; other site
431946013615	nucleotide binding site [chemical binding]; other site
431946013616	homodimer interface [polypeptide binding]; other site
431946013617	arginine deiminase; Provisional; Region: PRK01388
431946013618	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
431946013619	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
431946013620	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
431946013621	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
431946013622	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3076
431946013623	RNase E inhibitor protein; Provisional; Region: PRK11191
431946013624	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
431946013625	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
431946013626	Coenzyme A binding pocket [chemical binding]; other site
431946013627	Bacterial protein of unknown function (DUF898); Region: DUF898; cl01738
431946013628	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
431946013629	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
431946013630	HIGH motif; other site
431946013631	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
431946013632	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
431946013633	active site
431946013634	KMSKS motif; other site
431946013635	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
431946013636	tRNA binding surface [nucleotide binding]; other site
431946013637	anticodon binding site; other site
431946013638	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
431946013639	DNA polymerase III subunit chi; Validated; Region: PRK05728
431946013640	multifunctional aminopeptidase A; Provisional; Region: PRK00913
431946013641	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
431946013642	interface (dimer of trimers) [polypeptide binding]; other site
431946013643	Substrate-binding/catalytic site; other site
431946013644	Zn-binding sites [ion binding]; other site
431946013645	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
431946013646	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
431946013647	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
431946013648	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
431946013649	Bacterial protein of unknown function (DUF853); Region: DUF853; pfam05872
431946013650	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
431946013651	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
431946013652	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
431946013653	DNA binding site [nucleotide binding]
431946013654	domain linker motif; other site
431946013655	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
431946013656	putative dimerization interface [polypeptide binding]; other site
431946013657	putative ligand binding site [chemical binding]; other site
431946013658	fructuronate transporter; Provisional; Region: PRK10034; cl15264
431946013659	gluconate transporter; Region: gntP; TIGR00791
431946013660	gluconate 5-dehydrogenase; Provisional; Region: PRK08085
431946013661	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
431946013662	NADP binding site [chemical binding]; other site
431946013663	homodimer interface [polypeptide binding]; other site
431946013664	active site
431946013665	L-idonate 5-dehydrogenase; Provisional; Region: PRK09880
431946013666	L-idonate 5-dehydrogenase; Region: idonate-5-DH; cd08232
431946013667	putative NAD(P) binding site [chemical binding]; other site
431946013668	catalytic Zn binding site [ion binding]; other site
431946013669	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
431946013670	ATP-binding site [chemical binding]; other site
431946013671	Gluconate-6-phosphate binding site [chemical binding]; other site
431946013672	Shikimate kinase; Region: SKI; pfam01202
431946013673	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
431946013674	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
431946013675	putative NAD(P) binding site [chemical binding]; other site
431946013676	putative substrate binding site [chemical binding]; other site
431946013677	catalytic Zn binding site [ion binding]; other site
431946013678	structural Zn binding site [ion binding]; other site
431946013679	dimer interface [polypeptide binding]; other site
431946013680	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
431946013681	Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N2; pfam13495
431946013682	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
431946013683	active site
431946013684	catalytic residues [active]
431946013685	DNA binding site [nucleotide binding]
431946013686	Int/Topo IB signature motif; other site
431946013687	integrating conjugative element relaxase, PFL_4751 family; Region: ICE_TraI_Pfluor; TIGR03760
431946013688	Putative helicase; Region: TraI_2; pfam07514
431946013689	Protein of unknown function (DUF1528); Region: DUF1528; pfam07515
431946013690	Domain of unknown function (DUF1738); Region: DUF1738; pfam08401
431946013691	Antirestriction protein [DNA replication, recombination, and repair]; Region: COG4227
431946013692	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3440
431946013693	HNH endonuclease; Region: HNH_2; pfam13391
431946013694	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c_3; pfam13589
431946013695	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
431946013696	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946013697	ATP binding site [chemical binding]; other site
431946013698	Mg2+ binding site [ion binding]; other site
431946013699	G-X-G motif; other site
431946013700	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
431946013701	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
431946013702	cofactor binding site; other site
431946013703	DNA binding site [nucleotide binding]
431946013704	substrate interaction site [chemical binding]; other site
431946013705	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
431946013706	Homeodomain-like domain; Region: HTH_23; pfam13384
431946013707	Winged helix-turn helix; Region: HTH_29; pfam13551
431946013708	Winged helix-turn helix; Region: HTH_33; pfam13592
431946013709	DDE superfamily endonuclease; Region: DDE_3; pfam13358
431946013710	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
431946013711	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
431946013712	salt bridge; other site
431946013713	non-specific DNA binding site [nucleotide binding]; other site
431946013714	sequence-specific DNA binding site [nucleotide binding]; other site
431946013715	Fic family protein [Function unknown]; Region: COG3177
431946013716	Fic/DOC family N-terminal; Region: Fic_N; pfam13784
431946013717	Fic/DOC family; Region: Fic; pfam02661
431946013718	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
431946013719	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
431946013720	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
431946013721	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
431946013722	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
431946013723	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
431946013724	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
431946013725	putative active site [active]
431946013726	PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002
431946013727	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
431946013728	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
431946013729	active site turn [active]
431946013730	phosphorylation site [posttranslational modification]
431946013731	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
431946013732	N-acetylmannosamine-6-phosphate 2-epimerase; Provisional; Region: PRK01130
431946013733	putative active site cavity [active]
431946013734	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
431946013735	Transcriptional regulators [Transcription]; Region: PurR; COG1609
431946013736	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
431946013737	DNA binding site [nucleotide binding]
431946013738	domain linker motif; other site
431946013739	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
431946013740	putative dimerization interface [polypeptide binding]; other site
431946013741	putative ligand binding site [chemical binding]; other site
431946013742	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
431946013743	active site
431946013744	phosphorylation site [posttranslational modification]
431946013745	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
431946013746	active site
431946013747	P-loop; other site
431946013748	phosphorylation site [posttranslational modification]
431946013749	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK09410
431946013750	Transposase; Region: HTH_Tnp_1; pfam01527
431946013751	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
431946013752	deoxyribose mutarotase_like; Region: deoxyribose_mutarotase; cd09269
431946013753	active site
431946013754	catalytic residues [active]
431946013755	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
431946013756	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946013757	putative substrate translocation pore; other site
431946013758	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
431946013759	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
431946013760	substrate binding site [chemical binding]; other site
431946013761	dimer interface [polypeptide binding]; other site
431946013762	ATP binding site [chemical binding]; other site
431946013763	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
431946013764	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
431946013765	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
431946013766	Esterase-like activity of phytase; Region: Phytase-like; pfam13449
431946013767	Dimerization/Docking domain of Cyclic GMP-dependent Protein Kinase I; Region: DD_cGKI; cl17044
431946013768	homodimer interface [polypeptide binding]; other site
431946013769	putative GKAP docking site [polypeptide binding]; other site
431946013770	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
431946013771	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
431946013772	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
431946013773	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
431946013774	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
431946013775	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
431946013776	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
431946013777	Transposase; Region: HTH_Tnp_1; pfam01527
431946013778	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
431946013779	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
431946013780	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
431946013781	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
431946013782	Haemolysin expression modulating protein; Region: HHA; pfam05321
431946013783	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
431946013784	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
431946013785	Predicted GTPase [General function prediction only]; Region: COG3596
431946013786	YfjP GTPase; Region: YfjP; cd11383
431946013787	G1 box; other site
431946013788	GTP/Mg2+ binding site [chemical binding]; other site
431946013789	Switch I region; other site
431946013790	G2 box; other site
431946013791	Switch II region; other site
431946013792	G3 box; other site
431946013793	G4 box; other site
431946013794	G5 box; other site
431946013795	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
431946013796	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
431946013797	hypothetical protein; Provisional; Region: PRK09945
431946013798	DNA replication protein [DNA replication, recombination, and repair]; Region: DnaC; COG1484
431946013799	IstB-like ATP binding N-terminal; Region: IstB_IS21_ATP; pfam08483
431946013800	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946013801	Walker A motif; other site
431946013802	ATP binding site [chemical binding]; other site
431946013803	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
431946013804	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
431946013805	DNA binding residues [nucleotide binding]
431946013806	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
431946013807	Integrase core domain; Region: rve; pfam00665
431946013808	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
431946013809	hypothetical protein; Provisional; Region: PRK09945
431946013810	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
431946013811	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
431946013812	Autotransporter beta-domain; Region: Autotransporter; smart00869
431946013813	Bacterial protein of unknown function (DUF905); Region: DUF905; pfam06006
431946013814	Domain of unknown function (DUF932); Region: DUF932; pfam06067
431946013815	Antirestriction protein; Region: Antirestrict; pfam03230
431946013816	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
431946013817	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
431946013818	MPN+ (JAMM) motif; other site
431946013819	Zinc-binding site [ion binding]; other site
431946013820	Protein of unknown function (DUF987); Region: DUF987; pfam06174
431946013821	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
431946013822	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
431946013823	Enterobacterial protein of unknown function (DUF957); Region: DUF957; pfam06117
431946013824	Helix-turn-helix domain; Region: HTH_28; pfam13518
431946013825	type II restriction m6 adenine DNA methyltransferase, Alw26I/Eco31I/Esp3I family; Region: met_A_Alw26; TIGR02987
431946013826	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
431946013827	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
431946013828	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
431946013829	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
431946013830	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
431946013831	cofactor binding site; other site
431946013832	DNA binding site [nucleotide binding]
431946013833	substrate interaction site [chemical binding]; other site
431946013834	Type II restriction endonuclease (RE_Alw26IDE); Region: RE_Alw26IDE; pfam09665
431946013835	type II restriction endonuclease, Alw26I/Eco31I/Esp3I family; Region: restrict_Alw26I; TIGR02986
431946013836	McrBC 5-methylcytosine restriction system component; Region: McrBC; pfam10117
431946013837	AAA domain (dynein-related subfamily); Region: AAA_5; pfam07728
431946013838	potential frameshift: common BLAST hit: gi|300716585|ref|YP_003741388.1| glycosyl transferase family protein
431946013839	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
431946013840	active site
431946013841	methylthioribose kinase; Reviewed; Region: mtnK; PRK09550
431946013842	Phosphotransferase enzyme family; Region: APH; pfam01636
431946013843	methylthioribose-1-phosphate isomerase; Reviewed; Region: mtnA; PRK05720
431946013844	S-methyl-5-thioribose-1-phosphate isomerase; Region: salvage_mtnA; TIGR00512
431946013845	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cl00214
431946013846	intersubunit interface [polypeptide binding]; other site
431946013847	active site
431946013848	Zn2+ binding site [ion binding]; other site
431946013849	Putative glucose uptake permease [Carbohydrate transport and metabolism]; Region: GlcU; COG4975
431946013850	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
431946013851	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
431946013852	DNA binding residues [nucleotide binding]
431946013853	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
431946013854	gluconate transporter; Region: gntP; TIGR00791
431946013855	fructuronate transporter; Provisional; Region: PRK10034; cl15264
431946013856	putative dehydratase; Provisional; Region: PRK08211
431946013857	Dehydratase family; Region: ILVD_EDD; cl00340
431946013858	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
431946013859	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
431946013860	inhibitor site; inhibition site
431946013861	active site
431946013862	dimer interface [polypeptide binding]; other site
431946013863	catalytic residue [active]
431946013864	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
431946013865	Transcriptional regulator [Transcription]; Region: IclR; COG1414
431946013866	Bacterial transcriptional regulator; Region: IclR; pfam01614
431946013867	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
431946013868	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
431946013869	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
431946013870	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
431946013871	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
431946013872	substrate binding site [chemical binding]; other site
431946013873	hexamer interface [polypeptide binding]; other site
431946013874	metal binding site [ion binding]; metal-binding site
431946013875	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
431946013876	active site
431946013877	phosphorylation site [posttranslational modification]
431946013878	membrane complex biogenesis protein, BtpA family; Region: thylakoid_BtpA; TIGR00259
431946013879	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
431946013880	PTS system, galactitol-specific IIC component; Region: EIIC-GAT; TIGR00827
431946013881	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
431946013882	active site
431946013883	P-loop; other site
431946013884	phosphorylation site [posttranslational modification]
431946013885	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
431946013886	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
431946013887	oligomer interface [polypeptide binding]; other site
431946013888	active site
431946013889	metal binding site [ion binding]; metal-binding site
431946013890	Putative zinc ribbon domain; Region: Zn_ribbon_2; pfam12674
431946013891	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
431946013892	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946013893	S-adenosylmethionine binding site [chemical binding]; other site
431946013894	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
431946013895	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
431946013896	Coenzyme A binding pocket [chemical binding]; other site
431946013897	hypothetical protein; Provisional; Region: PRK13687
431946013898	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
431946013899	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
431946013900	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
431946013901	AAA domain; Region: AAA_12; pfam13087
431946013902	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
431946013903	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
431946013904	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
431946013905	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
431946013906	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
431946013907	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
431946013908	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
431946013909	Transposase; Region: HTH_Tnp_1; pfam01527
431946013910	C-terminal domain of Escherichia coli uncharacterized protein yjhR and similar proteins; Region: PLDc_yjhR_C_like; cd09118
431946013911	PLD-like domain; Region: PLDc_2; pfam13091
431946013912	putative active site [active]
431946013913	catalytic site [active]
431946013914	Domain of unknown function (DUF303); Region: DUF303; pfam03629
431946013915	N-acetylneuraminic acid mutarotase; Provisional; Region: PRK14131
431946013916	Kelch motif; Region: Kelch_1; pfam01344
431946013917	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; cl11629
431946013918	FimB and FimE and related proteins, DNA breaking-rejoining enzymes, integrase/recombinases, catalytic domain. This CD includes those proteins similar to E.coli FimE and FimB regulatory proteins and Proteus mirabilis MrpI; Region: INT_FimBE_C; cd01197
431946013919	Int/Topo IB signature motif; other site
431946013920	FimB and FimE and related proteins, DNA breaking-rejoining enzymes, integrase/recombinases, catalytic domain. This CD includes those proteins similar to E.coli FimE and FimB regulatory proteins and Proteus mirabilis MrpI; Region: INT_FimBE_C; cd01197
431946013921	Int/Topo IB signature motif; other site
431946013922	Fimbrial protein; Region: Fimbrial; cl01416
431946013923	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
431946013924	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
431946013925	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
431946013926	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
431946013927	outer membrane usher protein; Provisional; Region: PRK15193
431946013928	PapC N-terminal domain; Region: PapC_N; pfam13954
431946013929	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
431946013930	PapC C-terminal domain; Region: PapC_C; pfam13953
431946013931	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
431946013932	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
431946013933	Mannose binding  domain of FimH and related proteins; Region: FimH_man-bind; cd10466
431946013934	mannosyl binding site [chemical binding]; other site
431946013935	Fimbrial protein; Region: Fimbrial; pfam00419
431946013936	fructuronate transporter; Provisional; Region: PRK10034
431946013937	gluconate transporter; Region: gntP; TIGR00791
431946013938	mannonate dehydratase; Region: uxuA; TIGR00695
431946013939	mannonate dehydratase; Provisional; Region: PRK03906
431946013940	D-mannonate oxidoreductase; Provisional; Region: PRK15037
431946013941	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
431946013942	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
431946013943	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
431946013944	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
431946013945	DNA-binding site [nucleotide binding]; DNA binding site
431946013946	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
431946013947	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
431946013948	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
431946013949	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
431946013950	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
431946013951	Protein of unknown function (DUF2686); Region: DUF2686; pfam10887
431946013952	DNA replication/recombination/repair protein; Provisional; Region: iraD; PRK14128
431946013953	cell density-dependent motility repressor; Provisional; Region: PRK10082
431946013954	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
431946013955	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
431946013956	Isoaspartyl dipeptidase hydrolyzes the beta-L-isoaspartyl linkages in dipeptides, as part of the degradative pathway to eliminate proteins with beta-L-isoaspartyl peptide bonds, bonds whereby the beta-group of an aspartate forms the peptide link with the...; Region: Isoaspartyl-dipeptidase; cd01308
431946013957	isoaspartyl dipeptidase IadA; Region: isoAsp_dipep; TIGR01975
431946013958	dimer interface [polypeptide binding]; other site
431946013959	active site
431946013960	hypothetical protein; Provisional; Region: PRK10519
431946013961	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
431946013962	Nucleoside recognition; Region: Gate; pfam07670
431946013963	RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; Region: KptA; COG1859
431946013964	RNA 2'-phosphotransferase; Reviewed; Region: PRK00819
431946013965	Protein of unknown function (DUF1228); Region: DUF1228; pfam06779
431946013966	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3204
431946013967	SdiA-regulated; Region: SdiA-regulated; cd09971
431946013968	putative active site [active]
431946013969	Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism]; Region: COG1924
431946013970	CoA-substrate-specific enzyme activase, putative; Region: CoA_E_activ; TIGR00241
431946013971	Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB [Amino acid transport and metabolism]; Region: HgdB; COG1775
431946013972	benzoyl-CoA reductase, subunit C; Region: benz_CoA_red_C; TIGR02263
431946013973	Predicted membrane protein [Function unknown]; Region: COG2733
431946013974	Protein of unknown function (DUF2623); Region: DUF2623; pfam11115
431946013975	multidrug efflux system protein MdtM; Provisional; Region: PRK15403
431946013976	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946013977	putative substrate translocation pore; other site
431946013978	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
431946013979	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
431946013980	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
431946013981	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
431946013982	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
431946013983	Protein of unknown function (DUF497); Region: DUF497; cl01108
431946013984	Domain of unknown function (DUF4415); Region: DUF4415; cl01401
431946013985	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
431946013986	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
431946013987	P-loop, Walker A motif; other site
431946013988	Base recognition motif; other site
431946013989	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
431946013990	Uncharacterized small protein [Function unknown]; Region: COG2879
431946013991	carbon starvation protein A; Provisional; Region: PRK15015
431946013992	Carbon starvation protein CstA; Region: CstA; pfam02554
431946013993	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
431946013994	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
431946013995	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
431946013996	dimer interface [polypeptide binding]; other site
431946013997	ligand binding site [chemical binding]; other site
431946013998	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
431946013999	dimerization interface [polypeptide binding]; other site
431946014000	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
431946014001	dimer interface [polypeptide binding]; other site
431946014002	putative CheW interface [polypeptide binding]; other site
431946014003	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
431946014004	D-galactonate transporter; Region: 2A0114; TIGR00893
431946014005	putative substrate translocation pore; other site
431946014006	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
431946014007	DNA-binding site [nucleotide binding]; DNA binding site
431946014008	Transcriptional regulators [Transcription]; Region: GntR; COG1802
431946014009	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
431946014010	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
431946014011	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
431946014012	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
431946014013	putative NAD(P) binding site [chemical binding]; other site
431946014014	catalytic Zn binding site [ion binding]; other site
431946014015	structural Zn binding site [ion binding]; other site
431946014016	phosphoglycerol transferase I; Provisional; Region: PRK03776
431946014017	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
431946014018	hypothetical protein; Provisional; Region: PRK11667
431946014019	DNA replication protein DnaC; Validated; Region: PRK07952
431946014020	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946014021	Walker A motif; other site
431946014022	ATP binding site [chemical binding]; other site
431946014023	Walker B motif; other site
431946014024	primosomal protein DnaI; Provisional; Region: PRK02854
431946014025	hypothetical protein; Provisional; Region: PRK09917
431946014026	Uncharacterized conserved protein [Function unknown]; Region: COG2966
431946014027	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
431946014028	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
431946014029	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
431946014030	DNA binding residues [nucleotide binding]
431946014031	dimerization interface [polypeptide binding]; other site
431946014032	DNA-binding transcriptional activator BglJ; Provisional; Region: PRK11475
431946014033	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
431946014034	DNA binding residues [nucleotide binding]
431946014035	dimerization interface [polypeptide binding]; other site
431946014036	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
431946014037	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
431946014038	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
431946014039	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
431946014040	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
431946014041	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
431946014042	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946014043	S-adenosylmethionine binding site [chemical binding]; other site
431946014044	DNA polymerase III subunit psi; Validated; Region: PRK06856
431946014045	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
431946014046	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
431946014047	Coenzyme A binding pocket [chemical binding]; other site
431946014048	dUMP phosphatase; Provisional; Region: PRK09449
431946014049	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
431946014050	motif II; other site
431946014051	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
431946014052	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
431946014053	G1 box; other site
431946014054	putative GEF interaction site [polypeptide binding]; other site
431946014055	GTP/Mg2+ binding site [chemical binding]; other site
431946014056	Switch I region; other site
431946014057	G2 box; other site
431946014058	G3 box; other site
431946014059	Switch II region; other site
431946014060	G4 box; other site
431946014061	G5 box; other site
431946014062	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
431946014063	periplasmic protein; Provisional; Region: PRK10568
431946014064	BON domain; Region: BON; pfam04972
431946014065	BON domain; Region: BON; pfam04972
431946014066	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
431946014067	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
431946014068	active site
431946014069	nucleophile elbow; other site
431946014070	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
431946014071	active site
431946014072	glycine radical enzyme activase, YjjW family; Region: activase_YjjW; TIGR04041
431946014073	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
431946014074	FeS/SAM binding site; other site
431946014075	hypothetical protein; Provisional; Region: PRK10977
431946014076	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
431946014077	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
431946014078	intersubunit interface [polypeptide binding]; other site
431946014079	active site
431946014080	catalytic residue [active]
431946014081	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
431946014082	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
431946014083	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
431946014084	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
431946014085	phosphopentomutase; Provisional; Region: PRK05362
431946014086	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
431946014087	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
431946014088	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
431946014089	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
431946014090	non-specific DNA binding site [nucleotide binding]; other site
431946014091	salt bridge; other site
431946014092	sequence-specific DNA binding site [nucleotide binding]; other site
431946014093	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
431946014094	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
431946014095	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
431946014096	hypothetical protein; Provisional; Region: PRK11246
431946014097	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
431946014098	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
431946014099	motif II; other site
431946014100	DNA repair protein RadA; Region: sms; TIGR00416
431946014101	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
431946014102	Walker A motif/ATP binding site; other site
431946014103	ATP binding site [chemical binding]; other site
431946014104	Walker B motif; other site
431946014105	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
431946014106	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
431946014107	non-specific DNA binding site [nucleotide binding]; other site
431946014108	salt bridge; other site
431946014109	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
431946014110	sequence-specific DNA binding site [nucleotide binding]; other site
431946014111	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
431946014112	active site
431946014113	(T/H)XGH motif; other site
431946014114	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
431946014115	Protein of unknown function (DUF1044); Region: DUF1044; cl01955
431946014116	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
431946014117	non-specific DNA binding site [nucleotide binding]; other site
431946014118	salt bridge; other site
431946014119	sequence-specific DNA binding site [nucleotide binding]; other site
431946014120	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
431946014121	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
431946014122	Walker A/P-loop; other site
431946014123	ATP binding site [chemical binding]; other site
431946014124	Q-loop/lid; other site
431946014125	ABC transporter signature motif; other site
431946014126	Walker B; other site
431946014127	D-loop; other site
431946014128	H-loop/switch region; other site
431946014129	ABC transporter; Region: ABC_tran_2; pfam12848
431946014130	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
431946014131	lytic murein transglycosylase; Provisional; Region: PRK11619
431946014132	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
431946014133	N-acetyl-D-glucosamine binding site [chemical binding]; other site
431946014134	catalytic residue [active]
431946014135	Trp operon repressor; Provisional; Region: PRK01381
431946014136	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
431946014137	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
431946014138	catalytic core [active]
431946014139	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
431946014140	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
431946014141	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
431946014142	hypothetical protein; Provisional; Region: PRK10756
431946014143	CreA protein; Region: CreA; pfam05981
431946014144	DNA-binding response regulator CreB; Provisional; Region: PRK11083
431946014145	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946014146	active site
431946014147	phosphorylation site [posttranslational modification]
431946014148	intermolecular recognition site; other site
431946014149	dimerization interface [polypeptide binding]; other site
431946014150	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
431946014151	DNA binding site [nucleotide binding]
431946014152	sensory histidine kinase CreC; Provisional; Region: PRK11100
431946014153	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
431946014154	dimerization interface [polypeptide binding]; other site
431946014155	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
431946014156	dimer interface [polypeptide binding]; other site
431946014157	phosphorylation site [posttranslational modification]
431946014158	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
431946014159	ATP binding site [chemical binding]; other site
431946014160	Mg2+ binding site [ion binding]; other site
431946014161	G-X-G motif; other site
431946014162	Inner membrane protein involved in colicin E2 resistance [Defense mechanisms]; Region: CreD; COG4452
431946014163	two-component response regulator; Provisional; Region: PRK11173
431946014164	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
431946014165	active site
431946014166	phosphorylation site [posttranslational modification]
431946014167	intermolecular recognition site; other site
431946014168	dimerization interface [polypeptide binding]; other site
431946014169	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
431946014170	DNA binding site [nucleotide binding]
431946014171	putative RNA methyltransferase; Provisional; Region: PRK10433
431946014172	RNA methyltransferase, TrmH family, group 1; Region: rRNA_methyl_1; TIGR00050
431946014173	ParB-like nuclease domain; Region: ParB; smart00470
431946014174	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
431946014175	KorB domain; Region: KorB; pfam08535
431946014176	plasmid SOS inhibition protein B; Provisional; Region: psiB; PRK13701
431946014177	plasmid SOS inhibition protein A; Provisional; Region: PRK13704
431946014178	modulator of post-segregation killing protein; Provisional; Region: PRK13720
431946014179	Domain of unknown function (DUF932); Region: DUF932; pfam06067
431946014180	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
431946014181	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
431946014182	N-acetyl-D-glucosamine binding site [chemical binding]; other site
431946014183	catalytic residue [active]
431946014184	TraM protein; Region: Tra_M; pfam05261
431946014185	PAS fold; Region: PAS; pfam00989
431946014186	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
431946014187	conjugal transfer protein TraY; Provisional; Region: PRK13740
431946014188	conjugal transfer pilin subunit TraA; Provisional; Region: PRK13734
431946014189	conjugal transfer pilus assembly protein TraL; Provisional; Region: PRK13707
431946014190	conjugal transfer pilus assembly protein TraE; Provisional; Region: PRK13726
431946014191	conjugal transfer protein TraK; Provisional; Region: PRK13736
431946014192	TraK protein; Region: TraK; pfam06586
431946014193	conjugal transfer pilus assembly protein TraB; Provisional; Region: PRK13729
431946014194	Bacterial conjugation TrbI-like protein; Region: TrbI; pfam03743
431946014195	conjugal transfer protein TraP; Provisional; Region: PRK13739
431946014196	conjugal transfer protein TrbD; Provisional; Region: PRK13724
431946014197	conjugal transfer protein TrbG; Provisional; Region: PRK13744
431946014198	conjugal transfer protein TraV; Provisional; Region: PRK13733
431946014199	Type IV conjugative transfer system lipoprotein (TraV); Region: TraV; pfam09676
431946014200	conjugal transfer protein TraR; Provisional; Region: PRK13715
431946014201	conjugal transfer ATP-binding protein TraC; Provisional; Region: PRK13721
431946014202	F pilus assembly Type-IV secretion system for plasmid transfer; Region: TraC_F_IV; pfam11130
431946014203	conjugal transfer protein TrbI; Provisional; Region: PRK13717
431946014204	conjugal transfer pilus assembly protein TraW; Provisional; Region: PRK13738
431946014205	conjugal transfer pilus assembly protein TraU; Provisional; Region: PRK13737
431946014206	conjugal transfer pilus assembly protein TrbC; Provisional; Region: PRK13730
431946014207	conjugal transfer mating pair stabilization protein TraN; Reviewed; Region: PRK12355
431946014208	conjugal transfer protein TrbE; Provisional; Region: PRK13718
431946014209	conjugal pilus assembly protein TraF; Provisional; Region: PRK13703
431946014210	F plasmid transfer operon protein; Region: TraF; pfam13728
431946014211	conjugal transfer protein TrbA; Provisional; Region: PRK13712
431946014212	conjugal transfer pilin chaperone TraQ; Provisional; Region: PRK13727
431946014213	conjugal transfer protein TrbB; Provisional; Region: PRK13728
431946014214	conjugal transfer protein TrbJ; Provisional; Region: PRK13711
431946014215	conjugal transfer protein TrbF; Provisional; Region: PRK13743
431946014216	conjugal transfer pilus assembly protein TraH; Provisional; Region: PRK13723
431946014217	conjugal transfer mating pair stabilization protein TraG; Provisional; Region: PRK13735
431946014218	Plasmid conjugative transfer entry exclusion protein TraS; Region: TraS; pfam10624
431946014219	conjugal transfer surface exclusion protein TraT; Provisional; Region: PRK13731
431946014220	Enterobacterial TraT complement resistance protein; Region: TraT; pfam05818
431946014221	conjugal transfer protein TraD; Provisional; Region: PRK13700
431946014222	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
431946014223	Transposase; Region: HTH_Tnp_1; pfam01527
431946014224	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
431946014225	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
431946014226	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
431946014227	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
431946014228	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
431946014229	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
431946014230	conjugal transfer protein TraD; Provisional; Region: PRK13700
431946014231	F sex factor protein N terminal; Region: TraD_N; pfam12615
431946014232	Bacterial conjugation protein TrwB,  ATP binding domain. TrwB is a homohexamer encoded by conjugative plasmids in Gram-negative bacteria. TrwB also has an all alpha domain which has been hypothesized to be responsible for DNA binding. TrwB is a component...; Region: TrwB; cd01127
431946014233	multimer interface [polypeptide binding]; other site
431946014234	Walker A motif; other site
431946014235	ATP binding site [chemical binding]; other site
431946014236	Walker B motif; other site
431946014237	conjugal transfer nickase/helicase TraI; Provisional; Region: PRK13709
431946014238	conjugative relaxase domain, TrwC/TraI family; Region: relax_trwC; TIGR02686
431946014239	AAA domain; Region: AAA_30; pfam13604
431946014240	DNA helicase TraI; Region: TraI; pfam07057
431946014241	conjugal transfer pilus acetylation protein TraX; Provisional; Region: PRK13706
431946014242	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
431946014243	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
431946014244	alpha/beta hydrolase fold; Region: Abhydrolase_1; pfam00561
431946014245	conjugal transfer fertility inhibition protein FinO; Provisional; Region: PRK13754
431946014246	Fertility inhibition protein N terminal; Region: FinO_N; pfam12602
431946014247	FinO bacterial conjugation repressor domain;  the basic protein FinO is part of the the two component FinOP system which is responsible for repressing bacterial conjugation; the FinOP system represses the transfer (tra) operon of the F-plasmid which...; Region: FinO_conjug_rep; cd00236
431946014248	putative RNA binding sites [nucleotide binding]; other site
431946014249	Staphylococcal nuclease homologues; Region: SNc; smart00318
431946014250	Staphylococcal nuclease homologues. SNase homologues are found in bacteria, archaea, and eukaryotes. They contain no disufide bonds; Region: SNc; cd00175
431946014251	Catalytic site; other site
431946014252	Haemolysin expression modulating protein; Region: HHA; pfam05321
431946014253	Protein of unknown function (DUF2726); Region: DUF2726; pfam10881
431946014254	DNA replication protein [DNA replication, recombination, and repair]; Region: DnaC; COG1484
431946014255	IstB-like ATP binding N-terminal; Region: IstB_IS21_ATP; pfam08483
431946014256	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946014257	Walker A motif; other site
431946014258	ATP binding site [chemical binding]; other site
431946014259	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
431946014260	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
431946014261	DNA binding residues [nucleotide binding]
431946014262	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
431946014263	Integrase core domain; Region: rve; pfam00665
431946014264	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
431946014265	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
431946014266	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
431946014267	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
431946014268	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
431946014269	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
431946014270	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
431946014271	Transposase; Region: HTH_Tnp_1; pfam01527
431946014272	replication protein; Provisional; Region: PRK13702
431946014273	replication protein; Provisional; Region: PRK13750
431946014274	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316
431946014275	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
431946014276	Integrase core domain; Region: rve; pfam00665
431946014277	TlpA-like family, suppressor for copper sensitivity D protein (ScsD) and actinobacterial DsbE homolog subfamily; composed of ScsD, the DsbE homolog of Mycobacterium tuberculosis (MtbDsbE) and similar proteins, all containing a redox-active CXXC motif; Region: TlpA_like_ScsD_MtbDsbE; cd03011
431946014278	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
431946014279	catalytic residues [active]
431946014280	Na(+)-translocating NADH-quinone reductase subunit C; Provisional; Region: PRK05346
431946014281	NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit; Region: nqrC; TIGR01938
431946014282	High-affinity Fe2+/Pb2+ permease [Inorganic ion transport and metabolism]; Region: FTR1; COG0672
431946014283	Uncharacterized protein probably involved in high-affinity Fe2+ transport [Inorganic ion transport and metabolism]; Region: Tpd; COG3470
431946014284	Predicted membrane protein [Function unknown]; Region: COG4393
431946014285	Predicted membrane protein (DUF2318); Region: DUF2318; pfam10080
431946014286	Uncharacterized conserved protein [Function unknown]; Region: COG3350
431946014287	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
431946014288	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
431946014289	FtsX-like permease family; Region: FtsX; pfam02687
431946014290	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
431946014291	FtsX-like permease family; Region: FtsX; pfam02687
431946014292	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
431946014293	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
431946014294	Walker A/P-loop; other site
431946014295	ATP binding site [chemical binding]; other site
431946014296	Q-loop/lid; other site
431946014297	ABC transporter signature motif; other site
431946014298	Walker B; other site
431946014299	D-loop; other site
431946014300	H-loop/switch region; other site
431946014301	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
431946014302	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
431946014303	catalytic residues [active]
431946014304	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
431946014305	catalytic core [active]
431946014306	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
431946014307	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
431946014308	RT_like: Reverse transcriptase (RT, RNA-dependent DNA polymerase)_like family. An RT gene is usually indicative of a mobile element such as a retrotransposon or retrovirus. RTs occur in a variety of mobile elements, including retrotransposons; Region: RT_like; cl02808
431946014309	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
431946014310	HTH-like domain; Region: HTH_21; pfam13276
431946014311	Transposase; Region: HTH_Tnp_1; cl17663
431946014312	Colicin E1 (microcin) immunity protein; Region: Microcin; pfam03526
431946014313	Replicase family; Region: Replicase; pfam03090
431946014314	Primase C terminal 1 (PriCT-1); Region: PriCT_1; pfam08708
431946014315	Protein of unknown function, DUF399; Region: DUF399; pfam04187
431946014316	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
431946014317	TonB family C-terminal domain; Region: tonB_Cterm; TIGR01352
431946014318	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
431946014319	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
431946014320	Uncharacterized conserved protein [Function unknown]; Region: COG3391
431946014321	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
431946014322	Transposase; Region: HTH_Tnp_1; cl17663
431946014323	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
431946014324	DNA replication protein [DNA replication, recombination, and repair]; Region: DnaC; COG1484
431946014325	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946014326	Walker A motif; other site
431946014327	ATP binding site [chemical binding]; other site
431946014328	Walker B motif; other site
431946014329	Integrase core domain; Region: rve; pfam00665
431946014330	HTH-like domain; Region: HTH_21; pfam13276
431946014331	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
431946014332	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
431946014333	putative active site [active]
431946014334	putative NTP binding site [chemical binding]; other site
431946014335	putative nucleic acid binding site [nucleotide binding]; other site
431946014336	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
431946014337	Integrase core domain; Region: rve; pfam00665
431946014338	Transposase; Region: HTH_Tnp_1; pfam01527
431946014339	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
431946014340	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
431946014341	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
431946014342	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
431946014343	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
431946014344	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
431946014345	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
431946014346	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
431946014347	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
431946014348	DNA-binding interface [nucleotide binding]; DNA binding site
431946014349	Integrase core domain; Region: rve; pfam00665
431946014350	transposase/IS protein; Provisional; Region: PRK09183
431946014351	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946014352	Walker A motif; other site
431946014353	ATP binding site [chemical binding]; other site
431946014354	Walker B motif; other site
431946014355	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
431946014356	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
431946014357	Domain of unknown function (DUF4198); Region: DUF4198; pfam10670
431946014358	TonB-dependent heme/hemoglobin receptor family protein; Region: TonB-hemin; TIGR01785
431946014359	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
431946014360	N-terminal plug; other site
431946014361	ligand-binding site [chemical binding]; other site
431946014362	IS2 repressor TnpA; Reviewed; Region: PRK09413
431946014363	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
431946014364	Adhesin biosynthesis transcription regulatory protein; Region: PapB; pfam03333
431946014365	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
431946014366	active site
431946014367	catalytic residues [active]
431946014368	DNA binding site [nucleotide binding]
431946014369	Int/Topo IB signature motif; other site
431946014370	Initiator Replication protein; Region: Rep_3; cl03080
431946014371	plasmid maintenance protein CcdA; Provisional; Region: PRK13710
431946014372	plasmid maintenance protein CcdB; Provisional; Region: PRK13708
431946014373	Phage integrase family; Region: Phage_integrase; pfam00589
431946014374	active site
431946014375	DNA binding site [nucleotide binding]
431946014376	Int/Topo IB signature motif; other site
431946014377	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; cl15433
431946014378	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
431946014379	ParA-like protein; Provisional; Region: PHA02518
431946014380	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
431946014381	P-loop; other site
431946014382	Magnesium ion binding site [ion binding]; other site
431946014383	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
431946014384	Mg binding site [ion binding]; other site
431946014385	nucleotide binding site [chemical binding]; other site
431946014386	putative protofilament interface [polypeptide binding]; other site
431946014387	Plasmid stability protein; Region: Plasmid_stab_B; pfam10784
431946014388	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
431946014389	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
431946014390	active site
431946014391	DNA binding site [nucleotide binding]
431946014392	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
431946014393	Catalytic site [active]
431946014394	DinI-like family; Region: DinI; pfam06183
431946014395	Protein of unknown function (DUF1706); Region: DUF1706; pfam08020
431946014396	Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542
431946014397	Transposase; Region: DDE_Tnp_ISL3; pfam01610
431946014398	Protein of unknown function (DUF1281); Region: DUF1281; pfam06924
431946014399	transposase/IS protein; Provisional; Region: PRK09183
431946014400	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
431946014401	Walker A motif; other site
431946014402	ATP binding site [chemical binding]; other site
431946014403	Walker B motif; other site
431946014404	arginine finger; other site
431946014405	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
431946014406	Helix-turn-helix domain; Region: HTH_38; pfam13936
431946014407	Integrase core domain; Region: rve; pfam00665
431946014408	Integrase core domain; Region: rve_3; cl15866
431946014409	putative methylase; Provisional; Region: PRK13699
431946014410	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
431946014411	Protein of unknown function (DUF1380); Region: DUF1380; pfam07128
431946014412	Antirestriction protein; Region: Antirestrict; pfam03230
431946014413	Mu B transposition protein, C terminal; Region: Phage-MuB_C; pfam09077
431946014414	Domain of unknown function (DUF3560); Region: DUF3560; pfam12083
431946014415	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
431946014416	S-adenosylmethionine binding site [chemical binding]; other site
431946014417	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
431946014418	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
431946014419	dimer interface [polypeptide binding]; other site
431946014420	ssDNA binding site [nucleotide binding]; other site
431946014421	tetramer (dimer of dimers) interface [polypeptide binding]; other site
431946014422	Bacterial protein of unknown function (DUF905); Region: DUF905; pfam06006