-- dump date   	20140619_091144
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
696406000001	replication protein; Provisional; Region: PRK13750
696406000002	Phage derived protein Gp49-like (DUF891); Region: Gp49; pfam05973
696406000003	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
696406000004	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
696406000005	salt bridge; other site
696406000006	non-specific DNA binding site [nucleotide binding]; other site
696406000007	sequence-specific DNA binding site [nucleotide binding]; other site
696406000008	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
696406000009	Fimbrial protein; Region: Fimbrial; pfam00419
696406000010	fimbrial outer membrane usher protein PefC; Provisional; Region: PRK15213
696406000011	PapC N-terminal domain; Region: PapC_N; pfam13954
696406000012	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
696406000013	PapC C-terminal domain; Region: PapC_C; pfam13953
696406000014	fimbrial chaperone protein PefD; Provisional; Region: PRK15211
696406000015	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
696406000016	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
696406000017	Fimbrial, major and minor subunit; Region: Fimbrial_K88; pfam02432
696406000018	Fimbrial, major and minor subunit; Region: Fimbrial_K88; pfam02432
696406000019	Fimbrial, major and minor subunit; Region: Fimbrial_K88; pfam02432
696406000020	Integrase core domain; Region: rve; pfam00665
696406000021	Integrase core domain; Region: rve_3; pfam13683
696406000022	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
696406000023	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
696406000024	putative active site [active]
696406000025	putative NTP binding site [chemical binding]; other site
696406000026	putative nucleic acid binding site [nucleotide binding]; other site
696406000027	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
696406000028	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
696406000029	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
696406000030	Protein of unknown function (DUF2699); Region: DUF2699; pfam10919
696406000031	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
696406000032	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
696406000033	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
696406000034	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
696406000035	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
696406000036	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
696406000037	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
696406000038	transmembrane helices; other site
696406000039	malate dehydrogenase; Provisional; Region: PRK13529
696406000040	Malic enzyme, N-terminal domain; Region: malic; pfam00390
696406000041	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
696406000042	NAD(P) binding site [chemical binding]; other site
696406000043	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
696406000044	Penicillin V acylase (PVA), also known as conjugated bile salt acid hydrolase (CBAH), catalyzes the hydrolysis of penicillin V to yield 6-amino penicillanic acid (6-APA), an important key intermediate of semisynthetic penicillins.  PVA has an N-terminal...; Region: Ntn_PVA; cd00542
696406000045	active site
696406000046	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
696406000047	acetoin reductase; Validated; Region: PRK08643
696406000048	NAD(P) binding site [chemical binding]; other site
696406000049	active site
696406000050	Transposase; Region: HTH_Tnp_1; pfam01527
696406000051	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
696406000052	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
696406000053	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
696406000054	N-terminal domain of reverse transcriptase; Region: RVT_N; pfam13655
696406000055	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
696406000056	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
696406000057	putative active site [active]
696406000058	putative NTP binding site [chemical binding]; other site
696406000059	putative nucleic acid binding site [nucleotide binding]; other site
696406000060	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
696406000061	Transposase; Region: HTH_Tnp_1; pfam01527
696406000062	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
696406000063	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
696406000064	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
696406000065	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
696406000066	CAAX protease self-immunity; Region: Abi; pfam02517
696406000067	PemK-like protein; Region: PemK; cl00995
696406000068	Protein of unknown function DUF262; Region: DUF262; pfam03235
696406000069	Uncharacterized conserved protein [Function unknown]; Region: COG1479
696406000070	Divergent AAA domain; Region: AAA_4; pfam04326
696406000071	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406000072	Walker A motif; other site
696406000073	ATP binding site [chemical binding]; other site
696406000074	Walker B motif; other site
696406000075	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
696406000076	Helix-turn-helix domain; Region: HTH_38; pfam13936
696406000077	Integrase core domain; Region: rve; pfam00665
696406000078	Integrase core domain; Region: rve_3; cl15866
696406000079	IS2 transposase TnpB; Reviewed; Region: PRK09409
696406000080	HTH-like domain; Region: HTH_21; pfam13276
696406000081	Transposase; Region: HTH_Tnp_1; cl17663
696406000082	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
696406000083	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
696406000084	IS2 transposase TnpB; Reviewed; Region: PRK09409
696406000085	HTH-like domain; Region: HTH_21; pfam13276
696406000086	Integrase core domain; Region: rve; pfam00665
696406000087	Integrase core domain; Region: rve_3; pfam13683
696406000088	Transposase; Region: HTH_Tnp_1; cl17663
696406000089	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
696406000090	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
696406000091	Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism]; Region: SacC; COG1621
696406000092	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
696406000093	substrate binding [chemical binding]; other site
696406000094	active site
696406000095	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
696406000096	LacY proton/sugar symporter; Region: LacY_symp; pfam01306
696406000097	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406000098	putative substrate translocation pore; other site
696406000099	Alpha-galactosidase [Carbohydrate transport and metabolism]; Region: GalA; COG3345
696406000100	Melibiase; Region: Melibiase; pfam02065
696406000101	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
696406000102	DNA binding site [nucleotide binding]
696406000103	domain linker motif; other site
696406000104	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
696406000105	Ligand-binding domain of DNA transcription repressors specific for raffinose (RafR) and alpha-glucosides (AglR) which are members of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_AglR_RafR_like; cd06271
696406000106	ligand binding site [chemical binding]; other site
696406000107	Integrase core domain; Region: rve; pfam00665
696406000108	Ion channel; Region: Ion_trans_2; pfam07885
696406000109	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
696406000110	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
696406000111	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
696406000112	PapC C-terminal domain; Region: PapC_C; pfam13953
696406000113	Caf1 Capsule antigen; Region: Antig_Caf1; pfam09255
696406000114	Caf1 Capsule antigen; Region: Antig_Caf1; pfam09255
696406000115	Phage integrase family; Region: Phage_integrase; pfam00589
696406000116	active site
696406000117	DNA binding site [nucleotide binding]
696406000118	Int/Topo IB signature motif; other site
696406000119	ParA-like protein; Provisional; Region: PHA02518
696406000120	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
696406000121	P-loop; other site
696406000122	Magnesium ion binding site [ion binding]; other site
696406000123	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
696406000124	Mg binding site [ion binding]; other site
696406000125	nucleotide binding site [chemical binding]; other site
696406000126	putative protofilament interface [polypeptide binding]; other site
696406000127	Plasmid stability protein; Region: Plasmid_stab_B; pfam10784
696406000128	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
696406000129	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
696406000130	active site
696406000131	DNA binding site [nucleotide binding]
696406000132	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
696406000133	Protein of unknown function (DUF1281); Region: DUF1281; pfam06924
696406000134	plasmid SOS inhibition protein B; Provisional; Region: psiB; PRK13701
696406000135	PsiA protein; Region: PsiA; cl11646
696406000136	Domain of unknown function (DUF932); Region: DUF932; pfam06067
696406000137	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
696406000138	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
696406000139	N-acetyl-D-glucosamine binding site [chemical binding]; other site
696406000140	catalytic residue [active]
696406000141	TraM protein; Region: Tra_M; pfam05261
696406000142	conjugal transfer transcriptional regulator TraJ; Provisional; Region: PRK13719
696406000143	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
696406000144	conjugal transfer pilin subunit TraA; Provisional; Region: PRK13734
696406000145	conjugal transfer pilus assembly protein TraL; Provisional; Region: PRK13707
696406000146	conjugal transfer pilus assembly protein TraE; Provisional; Region: PRK13726
696406000147	conjugal transfer protein TraK; Provisional; Region: PRK13736; cl05878
696406000148	TraK protein; Region: TraK; pfam06586
696406000149	conjugal transfer pilus assembly protein TraB; Provisional; Region: PRK13729
696406000150	Bacterial conjugation TrbI-like protein; Region: TrbI; pfam03743
696406000151	TraP protein; Region: TraP; cl11652
696406000152	TraP protein; Region: TraP; cl11652
696406000153	conjugal transfer protein TrbD; Provisional; Region: PRK13724
696406000154	conjugal transfer protein TraV; Provisional; Region: PRK13733
696406000155	Type IV conjugative transfer system lipoprotein (TraV); Region: TraV; pfam09676
696406000156	Sex factor F TraW protein N terminal; Region: TraW_N; cl10149
696406000157	conjugal transfer pilus assembly protein TraU; Provisional; Region: PRK13737
696406000158	F sex factor protein N terminal; Region: TraD_N; pfam12615
696406000159	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
696406000160	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
696406000161	active site
696406000162	catalytic residues [active]
696406000163	DNA binding site [nucleotide binding]
696406000164	Int/Topo IB signature motif; other site
696406000165	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
696406000166	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
696406000167	dimerization interface [polypeptide binding]; other site
696406000168	putative DNA binding site [nucleotide binding]; other site
696406000169	putative Zn2+ binding site [ion binding]; other site
696406000170	HTH-like domain; Region: HTH_21; pfam13276
696406000171	Integrase core domain; Region: rve; pfam00665
696406000172	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
696406000173	Transposase; Region: HTH_Tnp_1; cl17663
696406000174	putative transposase OrfB; Reviewed; Region: PHA02517
696406000175	Integrase core domain; Region: rve_3; pfam13683
696406000176	Transposase; Region: HTH_Tnp_1; cl17663
696406000177	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
696406000178	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
696406000179	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
696406000180	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
696406000181	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
696406000182	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
696406000183	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
696406000184	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
696406000185	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
696406000186	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
696406000187	Transposase; Region: HTH_Tnp_1; pfam01527
696406000188	Transposase; Region: HTH_Tnp_1; pfam01527
696406000189	Heat-stable enterotoxin B, secretory; Region: STb_secrete; pfam09075
696406000190	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
696406000191	MULE transposase domain; Region: MULE; pfam10551
696406000192	insertion element IS2 transposase InsD; Provisional; Region: PRK14702
696406000193	Helix-turn-helix domain; Region: HTH_28; pfam13518
696406000194	Winged helix-turn helix; Region: HTH_29; pfam13551
696406000195	Homeodomain-like domain; Region: HTH_32; pfam13565
696406000196	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
696406000197	Integrase core domain; Region: rve; pfam00665
696406000198	Integrase core domain; Region: rve_3; pfam13683
696406000199	Heat-labile enterotoxin alpha chain; Region: Enterotoxin_a; pfam01375
696406000200	Heat-labile enterotoxin beta chain; Region: Enterotoxin_b; pfam01376
696406000201	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
696406000202	Transposase; Region: HTH_Tnp_1; pfam01527
696406000203	putative transposase OrfB; Reviewed; Region: PHA02517
696406000204	HTH-like domain; Region: HTH_21; pfam13276
696406000205	Integrase core domain; Region: rve; pfam00665
696406000206	Integrase core domain; Region: rve_3; pfam13683
696406000207	conjugal transfer fertility inhibition protein FinO; Provisional; Region: PRK13754
696406000208	Fertility inhibition protein N terminal; Region: FinO_N; pfam12602
696406000209	FinO bacterial conjugation repressor domain;  the basic protein FinO is part of the the two component FinOP system which is responsible for repressing bacterial conjugation; the FinOP system represses the transfer (tra) operon of the F-plasmid which...; Region: FinO_conjug_rep; cd00236
696406000210	putative RNA binding sites [nucleotide binding]; other site
696406000211	TraX protein; Region: TraX; cl05434
696406000212	conjugal transfer nickase/helicase TraI; Provisional; Region: PRK13709
696406000213	conjugative relaxase domain, TrwC/TraI family; Region: relax_trwC; TIGR02686
696406000214	AAA domain; Region: AAA_30; pfam13604
696406000215	DNA helicase TraI; Region: TraI; pfam07057
696406000216	F sex factor protein N terminal; Region: TraD_N; pfam12615
696406000217	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
696406000218	Walker A motif; other site
696406000219	ATP binding site [chemical binding]; other site
696406000220	conjugal transfer mating pair stabilization protein TraG; Provisional; Region: PRK13735
696406000221	conjugal transfer pilus assembly protein TraH; Provisional; Region: PRK13723
696406000222	conjugal transfer protein TrbF; Provisional; Region: PRK13743
696406000223	conjugal transfer protein TrbB; Provisional; Region: PRK13728
696406000224	conjugal transfer protein TrbJ; Provisional; Region: PRK13711
696406000225	Type-F conjugative transfer system pilin chaperone (TraQ); Region: TraQ; cl11516
696406000226	conjugal transfer protein TrbA; Provisional; Region: PRK13712
696406000227	conjugal pilus assembly protein TraF; Provisional; Region: PRK13703
696406000228	F plasmid transfer operon protein; Region: TraF; pfam13728
696406000229	conjugal transfer mating pair stabilization protein TraN; Reviewed; Region: PRK12355
696406000230	conjugal transfer pilus assembly protein TrbC; Provisional; Region: PRK13730
696406000231	conjugal transfer pilus assembly protein TraU; Provisional; Region: PRK13737
696406000232	conjugal transfer pilus assembly protein TraW; Provisional; Region: PRK13738
696406000233	conjugal transfer ATP-binding protein TraC; Provisional; Region: PRK13721
696406000234	F pilus assembly Type-IV secretion system for plasmid transfer; Region: TraC_F_IV; pfam11130
696406000235	conjugal transfer protein TraV; Provisional; Region: PRK13733
696406000236	Type IV conjugative transfer system lipoprotein (TraV); Region: TraV; pfam09676
696406000237	conjugal transfer protein TraP; Provisional; Region: PRK13739
696406000238	conjugal transfer pilus assembly protein TraB; Provisional; Region: PRK13729
696406000239	Bacterial conjugation TrbI-like protein; Region: TrbI; pfam03743
696406000240	conjugal transfer protein TraK; Provisional; Region: PRK13736
696406000241	TraK protein; Region: TraK; pfam06586
696406000242	conjugal transfer pilus assembly protein TraE; Provisional; Region: PRK13726
696406000243	conjugal transfer pilus assembly protein TraL; Provisional; Region: PRK13707
696406000244	conjugal transfer pilin subunit TraA; Provisional; Region: PRK13734
696406000245	PAS fold; Region: PAS; pfam00989
696406000246	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
696406000247	conjugal transfer protein TraM; Provisional; Region: PRK13713
696406000248	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
696406000249	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
696406000250	N-acetyl-D-glucosamine binding site [chemical binding]; other site
696406000251	catalytic residue [active]
696406000252	Domain of unknown function (DUF932); Region: DUF932; pfam06067
696406000253	plasmid SOS inhibition protein A; Provisional; Region: PRK13704
696406000254	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
696406000255	ParB-like nuclease domain; Region: ParB; smart00470
696406000256	KorB domain; Region: KorB; pfam08535
696406000257	Bacterial protein of unknown function (DUF905); Region: DUF905; pfam06006
696406000258	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406000259	S-adenosylmethionine binding site [chemical binding]; other site
696406000260	Domain of unknown function (DUF3560); Region: DUF3560; pfam12083
696406000261	Antirestriction protein; Region: Antirestrict; pfam03230
696406000262	Protein of unknown function (DUF1472); Region: DUF1472; pfam07339
696406000263	Protein of unknown function (DUF3352); Region: DUF3352; pfam11832
696406000264	Protein of unknown function (DUF1380); Region: DUF1380; pfam07128
696406000265	putative methylase; Provisional; Region: PRK13699
696406000266	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
696406000267	N-terminal domain of reverse transcriptase; Region: RVT_N; pfam13655
696406000268	Retron-type reverse transcriptase [DNA replication, recombination, and repair]; Region: COG3344
696406000269	RT_G2_intron: Reverse transcriptases (RTs) with group II intron origin. RT transcribes DNA using RNA as template. Proteins in this subfamily are found in bacterial and mitochondrial group II introns. Their most probable ancestor was a retrotransposable...; Region: RT_G2_intron; cd01651
696406000270	putative active site [active]
696406000271	putative NTP binding site [chemical binding]; other site
696406000272	putative nucleic acid binding site [nucleotide binding]; other site
696406000273	Group II intron, maturase-specific domain; Region: GIIM; pfam08388
696406000274	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
696406000275	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
696406000276	active site
696406000277	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
696406000278	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
696406000279	ParB-like nuclease domain; Region: ParB; smart00470
696406000280	ParB family; Region: ParB; pfam08775
696406000281	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
696406000282	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
696406000283	P-loop; other site
696406000284	Magnesium ion binding site [ion binding]; other site
696406000285	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
696406000286	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
696406000287	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
696406000288	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
696406000289	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
696406000290	putative catalytic residues [active]
696406000291	putative nucleotide binding site [chemical binding]; other site
696406000292	putative aspartate binding site [chemical binding]; other site
696406000293	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
696406000294	dimer interface [polypeptide binding]; other site
696406000295	putative threonine allosteric regulatory site; other site
696406000296	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
696406000297	putative threonine allosteric regulatory site; other site
696406000298	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
696406000299	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
696406000300	homoserine kinase; Region: thrB; TIGR00191
696406000301	Protein of unknown function; Region: YhfT; pfam10797
696406000302	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
696406000303	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
696406000304	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
696406000305	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406000306	catalytic residue [active]
696406000307	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
696406000308	hypothetical protein; Validated; Region: PRK02101
696406000309	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
696406000310	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
696406000311	transaldolase-like protein; Provisional; Region: PTZ00411
696406000312	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
696406000313	active site
696406000314	dimer interface [polypeptide binding]; other site
696406000315	catalytic residue [active]
696406000316	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
696406000317	MPT binding site; other site
696406000318	trimer interface [polypeptide binding]; other site
696406000319	hypothetical protein; Provisional; Region: PRK10659
696406000320	hypothetical protein; Provisional; Region: PRK10236
696406000321	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
696406000322	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
696406000323	hypothetical protein; Provisional; Region: PRK10154
696406000324	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
696406000325	Nucleotide-binding domain of human HSPA9, Escherichia coli DnaK, and similar proteins; Region: HSPA9-like_NBD; cd11733
696406000326	nucleotide binding site [chemical binding]; other site
696406000327	NEF interaction site [polypeptide binding]; other site
696406000328	SBD interface [polypeptide binding]; other site
696406000329	chaperone protein DnaJ; Provisional; Region: PRK10767
696406000330	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
696406000331	HSP70 interaction site [polypeptide binding]; other site
696406000332	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
696406000333	substrate binding site [polypeptide binding]; other site
696406000334	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
696406000335	Zn binding sites [ion binding]; other site
696406000336	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
696406000337	dimer interface [polypeptide binding]; other site
696406000338	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
696406000339	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
696406000340	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
696406000341	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
696406000342	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406000343	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
696406000344	putative dimerization interface [polypeptide binding]; other site
696406000345	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
696406000346	PapC C-terminal domain; Region: PapC_C; pfam13953
696406000347	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
696406000348	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
696406000349	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
696406000350	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
696406000351	active site
696406000352	Riboflavin kinase; Region: Flavokinase; smart00904
696406000353	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
696406000354	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
696406000355	HIGH motif; other site
696406000356	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
696406000357	active site
696406000358	KMSKS motif; other site
696406000359	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
696406000360	tRNA binding surface [nucleotide binding]; other site
696406000361	anticodon binding site; other site
696406000362	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
696406000363	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
696406000364	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
696406000365	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
696406000366	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
696406000367	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
696406000368	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
696406000369	active site
696406000370	tetramer interface [polypeptide binding]; other site
696406000371	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
696406000372	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
696406000373	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
696406000374	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
696406000375	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
696406000376	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
696406000377	catalytic site [active]
696406000378	subunit interface [polypeptide binding]; other site
696406000379	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
696406000380	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
696406000381	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
696406000382	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
696406000383	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
696406000384	ATP-grasp domain; Region: ATP-grasp_4; cl17255
696406000385	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
696406000386	IMP binding site; other site
696406000387	dimer interface [polypeptide binding]; other site
696406000388	interdomain contacts; other site
696406000389	partial ornithine binding site; other site
696406000390	DNA-binding transcriptional activator CaiF; Provisional; Region: PRK11476
696406000391	carnitine operon protein CaiE; Provisional; Region: PRK13627
696406000392	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
696406000393	putative trimer interface [polypeptide binding]; other site
696406000394	putative metal binding site [ion binding]; other site
696406000395	carnitinyl-CoA dehydratase; Provisional; Region: PRK03580
696406000396	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
696406000397	substrate binding site [chemical binding]; other site
696406000398	oxyanion hole (OAH) forming residues; other site
696406000399	trimer interface [polypeptide binding]; other site
696406000400	putative crotonobetaine/carnitine-CoA ligase; Validated; Region: caiC; PRK08008
696406000401	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_DitJ_like; cd05934
696406000402	acyl-activating enzyme (AAE) consensus motif; other site
696406000403	putative AMP binding site [chemical binding]; other site
696406000404	putative active site [active]
696406000405	putative CoA binding site [chemical binding]; other site
696406000406	crotonobetainyl-CoA:carnitine CoA-transferase; Provisional; Region: PRK03525
696406000407	CoA-transferase family III; Region: CoA_transf_3; pfam02515
696406000408	crotonobetainyl-CoA dehydrogenase; Validated; Region: PRK03354
696406000409	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
696406000410	active site
696406000411	L-carnitine/gamma-butyrobetaine antiporter; Provisional; Region: PRK03356
696406000412	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
696406000413	Ligand binding site [chemical binding]; other site
696406000414	Electron transfer flavoprotein domain; Region: ETF; pfam01012
696406000415	putative electron transfer flavoprotein FixB; Provisional; Region: fixB; PRK03363
696406000416	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF; cd01985
696406000417	Ligand binding site [chemical binding]; other site
696406000418	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
696406000419	putative oxidoreductase FixC; Provisional; Region: PRK10157
696406000420	ferredoxin-like protein FixX; Provisional; Region: PRK15449
696406000421	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406000422	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
696406000423	putative substrate translocation pore; other site
696406000424	glutathione-regulated potassium-efflux system ancillary protein KefF; Provisional; Region: PRK00871
696406000425	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
696406000426	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
696406000427	TrkA-N domain; Region: TrkA_N; pfam02254
696406000428	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
696406000429	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
696406000430	folate binding site [chemical binding]; other site
696406000431	NADP+ binding site [chemical binding]; other site
696406000432	bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Region: apaH; TIGR00668
696406000433	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
696406000434	active site
696406000435	metal binding site [ion binding]; metal-binding site
696406000436	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
696406000437	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
696406000438	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
696406000439	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
696406000440	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
696406000441	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
696406000442	SurA N-terminal domain; Region: SurA_N; pfam09312
696406000443	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
696406000444	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
696406000445	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
696406000446	OstA-like protein; Region: OstA; pfam03968
696406000447	Organic solvent tolerance protein; Region: OstA_C; pfam04453
696406000448	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
696406000449	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
696406000450	putative metal binding site [ion binding]; other site
696406000451	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
696406000452	HSP70 interaction site [polypeptide binding]; other site
696406000453	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
696406000454	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
696406000455	active site
696406000456	ATP-dependent helicase HepA; Validated; Region: PRK04914
696406000457	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
696406000458	ATP binding site [chemical binding]; other site
696406000459	putative Mg++ binding site [ion binding]; other site
696406000460	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
696406000461	nucleotide binding region [chemical binding]; other site
696406000462	ATP-binding site [chemical binding]; other site
696406000463	DNA polymerase II; Reviewed; Region: PRK05762
696406000464	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
696406000465	active site
696406000466	catalytic site [active]
696406000467	substrate binding site [chemical binding]; other site
696406000468	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
696406000469	active site
696406000470	metal-binding site
696406000471	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
696406000472	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
696406000473	intersubunit interface [polypeptide binding]; other site
696406000474	active site
696406000475	Zn2+ binding site [ion binding]; other site
696406000476	L-arabinose isomerase; Provisional; Region: PRK02929
696406000477	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
696406000478	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
696406000479	trimer interface [polypeptide binding]; other site
696406000480	putative substrate binding site [chemical binding]; other site
696406000481	putative metal binding site [ion binding]; other site
696406000482	ribulokinase; Provisional; Region: PRK04123
696406000483	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
696406000484	N- and C-terminal domain interface [polypeptide binding]; other site
696406000485	active site
696406000486	MgATP binding site [chemical binding]; other site
696406000487	catalytic site [active]
696406000488	metal binding site [ion binding]; metal-binding site
696406000489	carbohydrate binding site [chemical binding]; other site
696406000490	homodimer interface [polypeptide binding]; other site
696406000491	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
696406000492	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
696406000493	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406000494	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406000495	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
696406000496	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
696406000497	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
696406000498	ATP-binding cassette domain of the thiamine transport system; Region: ABC_ThiQ_thiamine_transporter; cd03298
696406000499	Walker A/P-loop; other site
696406000500	ATP binding site [chemical binding]; other site
696406000501	Q-loop/lid; other site
696406000502	ABC transporter signature motif; other site
696406000503	Walker B; other site
696406000504	D-loop; other site
696406000505	H-loop/switch region; other site
696406000506	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
696406000507	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406000508	dimer interface [polypeptide binding]; other site
696406000509	conserved gate region; other site
696406000510	putative PBP binding loops; other site
696406000511	ABC-ATPase subunit interface; other site
696406000512	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406000513	dimer interface [polypeptide binding]; other site
696406000514	conserved gate region; other site
696406000515	putative PBP binding loops; other site
696406000516	ABC-ATPase subunit interface; other site
696406000517	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
696406000518	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
696406000519	transcriptional regulator SgrR; Provisional; Region: PRK13626
696406000520	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
696406000521	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
696406000522	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406000523	sugar efflux transporter; Region: 2A0120; TIGR00899
696406000524	putative substrate translocation pore; other site
696406000525	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
696406000526	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
696406000527	substrate binding site [chemical binding]; other site
696406000528	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
696406000529	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
696406000530	substrate binding site [chemical binding]; other site
696406000531	ligand binding site [chemical binding]; other site
696406000532	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
696406000533	tartrate dehydrogenase; Region: TTC; TIGR02089
696406000534	2-isopropylmalate synthase; Validated; Region: PRK00915
696406000535	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
696406000536	active site
696406000537	catalytic residues [active]
696406000538	metal binding site [ion binding]; metal-binding site
696406000539	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
696406000540	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
696406000541	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406000542	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
696406000543	putative substrate binding pocket [chemical binding]; other site
696406000544	putative dimerization interface [polypeptide binding]; other site
696406000545	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
696406000546	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
696406000547	PYR/PP interface [polypeptide binding]; other site
696406000548	dimer interface [polypeptide binding]; other site
696406000549	TPP binding site [chemical binding]; other site
696406000550	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
696406000551	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
696406000552	TPP-binding site [chemical binding]; other site
696406000553	dimer interface [polypeptide binding]; other site
696406000554	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
696406000555	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
696406000556	putative valine binding site [chemical binding]; other site
696406000557	dimer interface [polypeptide binding]; other site
696406000558	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
696406000559	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
696406000560	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
696406000561	DNA binding site [nucleotide binding]
696406000562	domain linker motif; other site
696406000563	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
696406000564	dimerization interface [polypeptide binding]; other site
696406000565	ligand binding site [chemical binding]; other site
696406000566	mraZ protein; Region: TIGR00242
696406000567	MraZ protein; Region: MraZ; pfam02381
696406000568	MraZ protein; Region: MraZ; pfam02381
696406000569	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
696406000570	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
696406000571	cell division protein FtsL; Provisional; Region: PRK10772
696406000572	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
696406000573	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
696406000574	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
696406000575	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
696406000576	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
696406000577	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
696406000578	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
696406000579	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
696406000580	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
696406000581	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
696406000582	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
696406000583	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
696406000584	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
696406000585	Mg++ binding site [ion binding]; other site
696406000586	putative catalytic motif [active]
696406000587	putative substrate binding site [chemical binding]; other site
696406000588	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
696406000589	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
696406000590	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
696406000591	cell division protein FtsW; Provisional; Region: PRK10774
696406000592	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
696406000593	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
696406000594	active site
696406000595	homodimer interface [polypeptide binding]; other site
696406000596	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
696406000597	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
696406000598	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
696406000599	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
696406000600	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
696406000601	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
696406000602	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
696406000603	cell division protein FtsQ; Provisional; Region: PRK10775
696406000604	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
696406000605	Cell division protein FtsQ; Region: FtsQ; pfam03799
696406000606	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
696406000607	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
696406000608	Cell division protein FtsA; Region: FtsA; pfam14450
696406000609	cell division protein FtsZ; Validated; Region: PRK09330
696406000610	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
696406000611	nucleotide binding site [chemical binding]; other site
696406000612	SulA interaction site; other site
696406000613	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
696406000614	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
696406000615	SecA regulator SecM; Provisional; Region: PRK02943
696406000616	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
696406000617	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
696406000618	SEC-C motif; Region: SEC-C; pfam02810
696406000619	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
696406000620	active site
696406000621	8-oxo-dGMP binding site [chemical binding]; other site
696406000622	nudix motif; other site
696406000623	metal binding site [ion binding]; metal-binding site
696406000624	DNA gyrase inhibitor; Reviewed; Region: PRK00418
696406000625	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4582
696406000626	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
696406000627	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
696406000628	CoA-binding site [chemical binding]; other site
696406000629	ATP-binding [chemical binding]; other site
696406000630	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
696406000631	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
696406000632	active site
696406000633	type IV pilin biogenesis protein; Provisional; Region: PRK10573
696406000634	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
696406000635	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
696406000636	hypothetical protein; Provisional; Region: PRK10436
696406000637	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
696406000638	Walker A motif; other site
696406000639	ATP binding site [chemical binding]; other site
696406000640	Walker B motif; other site
696406000641	putative major pilin subunit; Provisional; Region: PRK10574
696406000642	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
696406000643	Pilin (bacterial filament); Region: Pilin; pfam00114
696406000644	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
696406000645	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
696406000646	dimerization interface [polypeptide binding]; other site
696406000647	active site
696406000648	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
696406000649	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
696406000650	amidase catalytic site [active]
696406000651	Zn binding residues [ion binding]; other site
696406000652	substrate binding site [chemical binding]; other site
696406000653	regulatory protein AmpE; Provisional; Region: PRK10987
696406000654	aromatic amino acid transporter; Provisional; Region: PRK10238
696406000655	Transcriptional regulators [Transcription]; Region: FadR; COG2186
696406000656	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
696406000657	DNA-binding site [nucleotide binding]; DNA binding site
696406000658	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
696406000659	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
696406000660	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
696406000661	dimer interface [polypeptide binding]; other site
696406000662	TPP-binding site [chemical binding]; other site
696406000663	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
696406000664	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
696406000665	E3 interaction surface; other site
696406000666	lipoyl attachment site [posttranslational modification]; other site
696406000667	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
696406000668	E3 interaction surface; other site
696406000669	lipoyl attachment site [posttranslational modification]; other site
696406000670	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
696406000671	E3 interaction surface; other site
696406000672	lipoyl attachment site [posttranslational modification]; other site
696406000673	e3 binding domain; Region: E3_binding; pfam02817
696406000674	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
696406000675	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
696406000676	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
696406000677	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
696406000678	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
696406000679	Protein of unknown function (DUF3300); Region: DUF3300; pfam11737
696406000680	Protein of unknown function (DUF3106); Region: DUF3106; pfam11304
696406000681	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cl01482
696406000682	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
696406000683	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
696406000684	substrate binding site [chemical binding]; other site
696406000685	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
696406000686	substrate binding site [chemical binding]; other site
696406000687	ligand binding site [chemical binding]; other site
696406000688	hypothetical protein; Provisional; Region: PRK05248
696406000689	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
696406000690	spermidine synthase; Provisional; Region: PRK00811
696406000691	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406000692	S-adenosylmethionine binding site [chemical binding]; other site
696406000693	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
696406000694	multicopper oxidase; Provisional; Region: PRK10965
696406000695	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
696406000696	Multicopper oxidase; Region: Cu-oxidase; pfam00394
696406000697	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
696406000698	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
696406000699	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
696406000700	Trp docking motif [polypeptide binding]; other site
696406000701	putative active site [active]
696406000702	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
696406000703	active site
696406000704	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
696406000705	active site clefts [active]
696406000706	zinc binding site [ion binding]; other site
696406000707	dimer interface [polypeptide binding]; other site
696406000708	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
696406000709	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
696406000710	Walker A/P-loop; other site
696406000711	ATP binding site [chemical binding]; other site
696406000712	Q-loop/lid; other site
696406000713	ABC transporter signature motif; other site
696406000714	Walker B; other site
696406000715	D-loop; other site
696406000716	H-loop/switch region; other site
696406000717	inner membrane transport permease; Provisional; Region: PRK15066
696406000718	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
696406000719	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
696406000720	active pocket/dimerization site; other site
696406000721	active site
696406000722	phosphorylation site [posttranslational modification]
696406000723	Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins; Region: CE4_yadE_5s; cd10966
696406000724	putative active site [active]
696406000725	putative metal binding site [ion binding]; other site
696406000726	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
696406000727	tetramerization interface [polypeptide binding]; other site
696406000728	active site
696406000729	Uncharacterized conserved protein [Function unknown]; Region: COG5464
696406000730	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
696406000731	pantoate--beta-alanine ligase; Region: panC; TIGR00018
696406000732	Pantoate-beta-alanine ligase; Region: PanC; cd00560
696406000733	active site
696406000734	ATP-binding site [chemical binding]; other site
696406000735	pantoate-binding site; other site
696406000736	HXXH motif; other site
696406000737	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
696406000738	oligomerization interface [polypeptide binding]; other site
696406000739	active site
696406000740	metal binding site [ion binding]; metal-binding site
696406000741	putative fimbrial-like adhesin protein; Provisional; Region: PRK09723
696406000742	putative fimbrial protein StaF; Provisional; Region: PRK15262
696406000743	putative fimbrial protein StaE; Provisional; Region: PRK15263
696406000744	Fimbrial protein; Region: Fimbrial; cl01416
696406000745	putative chaperone protein EcpD; Provisional; Region: PRK09926
696406000746	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
696406000747	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
696406000748	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
696406000749	Fimbrial protein; Region: Fimbrial; cl01416
696406000750	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
696406000751	catalytic center binding site [active]
696406000752	ATP binding site [chemical binding]; other site
696406000753	poly(A) polymerase I; Provisional; Region: pcnB; PRK11623
696406000754	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
696406000755	active site
696406000756	NTP binding site [chemical binding]; other site
696406000757	metal binding triad [ion binding]; metal-binding site
696406000758	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
696406000759	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
696406000760	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
696406000761	tRNA synthetases class I (E and Q), catalytic domain; Region: tRNA-synt_1c; pfam00749
696406000762	active site
696406000763	nucleotide binding site [chemical binding]; other site
696406000764	HIGH motif; other site
696406000765	KMSKS motif; other site
696406000766	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
696406000767	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
696406000768	2'-5' RNA ligase; Provisional; Region: PRK15124
696406000769	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
696406000770	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
696406000771	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
696406000772	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
696406000773	ATP binding site [chemical binding]; other site
696406000774	putative Mg++ binding site [ion binding]; other site
696406000775	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
696406000776	nucleotide binding region [chemical binding]; other site
696406000777	ATP-binding site [chemical binding]; other site
696406000778	Helicase associated domain (HA2) Add an annotation; Region: HA2; smart00847
696406000779	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
696406000780	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
696406000781	Transglycosylase; Region: Transgly; pfam00912
696406000782	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
696406000783	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
696406000784	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
696406000785	N-terminal plug; other site
696406000786	ligand-binding site [chemical binding]; other site
696406000787	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
696406000788	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
696406000789	Walker A/P-loop; other site
696406000790	ATP binding site [chemical binding]; other site
696406000791	Q-loop/lid; other site
696406000792	ABC transporter signature motif; other site
696406000793	Walker B; other site
696406000794	D-loop; other site
696406000795	H-loop/switch region; other site
696406000796	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
696406000797	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
696406000798	siderophore binding site; other site
696406000799	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
696406000800	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
696406000801	ABC-ATPase subunit  interface; other site
696406000802	dimer interface [polypeptide binding]; other site
696406000803	putative PBP binding regions; other site
696406000804	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
696406000805	ABC-ATPase subunit  interface; other site
696406000806	dimer interface [polypeptide binding]; other site
696406000807	putative PBP binding regions; other site
696406000808	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
696406000809	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
696406000810	inhibitor-cofactor binding pocket; inhibition site
696406000811	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406000812	catalytic residue [active]
696406000813	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
696406000814	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
696406000815	Cl- selectivity filter; other site
696406000816	Cl- binding residues [ion binding]; other site
696406000817	pore gating glutamate residue; other site
696406000818	dimer interface [polypeptide binding]; other site
696406000819	H+/Cl- coupling transport residue; other site
696406000820	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
696406000821	hypothetical protein; Provisional; Region: PRK10578
696406000822	UPF0126 domain; Region: UPF0126; pfam03458
696406000823	UPF0126 domain; Region: UPF0126; pfam03458
696406000824	vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379
696406000825	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
696406000826	cobalamin binding residues [chemical binding]; other site
696406000827	putative BtuC binding residues; other site
696406000828	dimer interface [polypeptide binding]; other site
696406000829	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
696406000830	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
696406000831	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
696406000832	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
696406000833	Zn2+ binding site [ion binding]; other site
696406000834	Mg2+ binding site [ion binding]; other site
696406000835	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
696406000836	serine endoprotease; Provisional; Region: PRK10942
696406000837	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
696406000838	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
696406000839	protein binding site [polypeptide binding]; other site
696406000840	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
696406000841	carbohydrate diacid transcriptional activator CdaR; Provisional; Region: PRK11477
696406000842	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
696406000843	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
696406000844	hypothetical protein; Provisional; Region: PRK13677
696406000845	phosphodiesterase YaeI; Provisional; Region: PRK11340
696406000846	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
696406000847	putative active site [active]
696406000848	putative metal binding site [ion binding]; other site
696406000849	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
696406000850	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
696406000851	trimer interface [polypeptide binding]; other site
696406000852	active site
696406000853	substrate binding site [chemical binding]; other site
696406000854	CoA binding site [chemical binding]; other site
696406000855	PII uridylyl-transferase; Provisional; Region: PRK05007
696406000856	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
696406000857	metal binding triad; other site
696406000858	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
696406000859	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
696406000860	Zn2+ binding site [ion binding]; other site
696406000861	Mg2+ binding site [ion binding]; other site
696406000862	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
696406000863	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
696406000864	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
696406000865	active site
696406000866	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
696406000867	rRNA interaction site [nucleotide binding]; other site
696406000868	S8 interaction site; other site
696406000869	putative laminin-1 binding site; other site
696406000870	elongation factor Ts; Provisional; Region: tsf; PRK09377
696406000871	UBA/TS-N domain; Region: UBA; pfam00627
696406000872	Elongation factor TS; Region: EF_TS; pfam00889
696406000873	Elongation factor TS; Region: EF_TS; pfam00889
696406000874	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
696406000875	putative nucleotide binding site [chemical binding]; other site
696406000876	uridine monophosphate binding site [chemical binding]; other site
696406000877	homohexameric interface [polypeptide binding]; other site
696406000878	ribosome recycling factor; Reviewed; Region: frr; PRK00083
696406000879	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
696406000880	hinge region; other site
696406000881	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
696406000882	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
696406000883	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
696406000884	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
696406000885	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
696406000886	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
696406000887	catalytic residue [active]
696406000888	putative FPP diphosphate  binding site; other site
696406000889	putative FPP binding hydrophobic cleft; other site
696406000890	dimer interface [polypeptide binding]; other site
696406000891	putative IPP diphosphate binding site; other site
696406000892	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
696406000893	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
696406000894	zinc metallopeptidase RseP; Provisional; Region: PRK10779
696406000895	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
696406000896	active site
696406000897	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
696406000898	protein binding site [polypeptide binding]; other site
696406000899	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
696406000900	putative substrate binding region [chemical binding]; other site
696406000901	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
696406000902	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
696406000903	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
696406000904	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
696406000905	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
696406000906	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
696406000907	Surface antigen; Region: Bac_surface_Ag; pfam01103
696406000908	periplasmic chaperone; Provisional; Region: PRK10780
696406000909	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
696406000910	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
696406000911	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
696406000912	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
696406000913	trimer interface [polypeptide binding]; other site
696406000914	active site
696406000915	UDP-GlcNAc binding site [chemical binding]; other site
696406000916	lipid binding site [chemical binding]; lipid-binding site
696406000917	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
696406000918	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
696406000919	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
696406000920	active site
696406000921	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
696406000922	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
696406000923	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
696406000924	RNA/DNA hybrid binding site [nucleotide binding]; other site
696406000925	active site
696406000926	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
696406000927	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
696406000928	putative active site [active]
696406000929	putative PHP Thumb interface [polypeptide binding]; other site
696406000930	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
696406000931	generic binding surface II; other site
696406000932	generic binding surface I; other site
696406000933	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
696406000934	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
696406000935	lysine decarboxylase LdcC; Provisional; Region: PRK15399
696406000936	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
696406000937	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
696406000938	homodimer interface [polypeptide binding]; other site
696406000939	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406000940	catalytic residue [active]
696406000941	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
696406000942	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
696406000943	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
696406000944	putative metal binding site [ion binding]; other site
696406000945	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
696406000946	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
696406000947	Ligand Binding Site [chemical binding]; other site
696406000948	TilS substrate binding domain; Region: TilS; pfam09179
696406000949	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
696406000950	Rho-binding antiterminator; Provisional; Region: PRK11625
696406000951	hypothetical protein; Provisional; Region: PRK04964
696406000952	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
696406000953	hypothetical protein; Provisional; Region: PRK09256
696406000954	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
696406000955	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
696406000956	NlpE N-terminal domain; Region: NlpE; pfam04170
696406000957	hypothetical protein; Provisional; Region: PRK11479
696406000958	Orthopoxvirus protein of unknown function (DUF830); Region: DUF830; cl13998
696406000959	NlpC/P60 family; Region: NLPC_P60; cl17555
696406000960	prolyl-tRNA synthetase; Provisional; Region: PRK09194
696406000961	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
696406000962	dimer interface [polypeptide binding]; other site
696406000963	motif 1; other site
696406000964	active site
696406000965	motif 2; other site
696406000966	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
696406000967	putative deacylase active site [active]
696406000968	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
696406000969	active site
696406000970	motif 3; other site
696406000971	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
696406000972	anticodon binding site; other site
696406000973	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
696406000974	homodimer interaction site [polypeptide binding]; other site
696406000975	cofactor binding site; other site
696406000976	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
696406000977	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
696406000978	lipoprotein, YaeC family; Region: TIGR00363
696406000979	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406000980	dimer interface [polypeptide binding]; other site
696406000981	conserved gate region; other site
696406000982	ABC-ATPase subunit interface; other site
696406000983	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
696406000984	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
696406000985	Walker A/P-loop; other site
696406000986	ATP binding site [chemical binding]; other site
696406000987	Q-loop/lid; other site
696406000988	ABC transporter signature motif; other site
696406000989	Walker B; other site
696406000990	D-loop; other site
696406000991	H-loop/switch region; other site
696406000992	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
696406000993	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
696406000994	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696406000995	active site
696406000996	motif I; other site
696406000997	motif II; other site
696406000998	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
696406000999	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
696406001000	active site
696406001001	catalytic tetrad [active]
696406001002	Transcriptional regulator [Transcription]; Region: LysR; COG0583
696406001003	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406001004	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA; cd08478
696406001005	putative effector binding pocket; other site
696406001006	dimerization interface [polypeptide binding]; other site
696406001007	hypothetical protein; Provisional; Region: PRK05421
696406001008	putative catalytic site [active]
696406001009	putative metal binding site [ion binding]; other site
696406001010	putative phosphate binding site [ion binding]; other site
696406001011	putative catalytic site [active]
696406001012	putative phosphate binding site [ion binding]; other site
696406001013	putative metal binding site [ion binding]; other site
696406001014	Methyltransferase domain; Region: Methyltransf_31; pfam13847
696406001015	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406001016	S-adenosylmethionine binding site [chemical binding]; other site
696406001017	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
696406001018	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
696406001019	N-acetyl-D-glucosamine binding site [chemical binding]; other site
696406001020	catalytic residue [active]
696406001021	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
696406001022	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
696406001023	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
696406001024	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
696406001025	hydroxyacylglutathione hydrolase; Provisional; Region: PRK10241
696406001026	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406001027	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
696406001028	RNA/DNA hybrid binding site [nucleotide binding]; other site
696406001029	active site
696406001030	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
696406001031	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
696406001032	active site
696406001033	catalytic site [active]
696406001034	substrate binding site [chemical binding]; other site
696406001035	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
696406001036	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
696406001037	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
696406001038	ImpA domain protein; Region: DUF3702; pfam12486
696406001039	ImcF-related N-terminal domain; Region: ImcF-related_N; pfam14331
696406001040	Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761
696406001041	Protein of unknown function (DUF1215); Region: DUF1215; pfam06744
696406001042	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
696406001043	motif I; other site
696406001044	active site
696406001045	ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812
696406001046	type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362
696406001047	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3515
696406001048	type VI secretion-associated protein, VC_A0118 family; Region: VI_minor_1; TIGR03360
696406001049	type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345
696406001050	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406001051	Walker A motif; other site
696406001052	ATP binding site [chemical binding]; other site
696406001053	Walker B motif; other site
696406001054	arginine finger; other site
696406001055	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406001056	Walker A motif; other site
696406001057	ATP binding site [chemical binding]; other site
696406001058	Walker B motif; other site
696406001059	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
696406001060	Type VI protein secretion system component VasF [Intracellular    trafficking, secretion, and vesicular transport]; Region: COG3455
696406001061	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3522
696406001062	Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936
696406001063	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3521
696406001064	Predicted component of the type VI protein secretion system, contains a FHA domain [Intracellular trafficking, secretion, and vesicular    transport; Signal transduction mechanisms]; Region: COG3456
696406001065	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3520
696406001066	Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3519
696406001067	Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947
696406001068	type VI secretion system lysozyme-like protein; Region: VI_zyme; TIGR03357
696406001069	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517
696406001070	Protein of unknown function (DUF877); Region: DUF877; pfam05943
696406001071	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3517; cl05484
696406001072	Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and    vesicular transport]; Region: COG3516
696406001073	type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344
696406001074	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
696406001075	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
696406001076	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
696406001077	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
696406001078	PAAR motif; Region: PAAR_motif; cl15808
696406001079	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
696406001080	RHS protein; Region: RHS; pfam03527
696406001081	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
696406001082	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
696406001083	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
696406001084	Transposase [DNA replication, recombination, and repair]; Region: COG5433
696406001085	Transposase [DNA replication, recombination, and repair]; Region: COG5433
696406001086	C-N hydrolase family amidase; Provisional; Region: PRK10438
696406001087	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
696406001088	putative active site [active]
696406001089	catalytic triad [active]
696406001090	dimer interface [polypeptide binding]; other site
696406001091	multimer interface [polypeptide binding]; other site
696406001092	C-lysozyme inhibitor; Provisional; Region: PRK09993
696406001093	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
696406001094	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
696406001095	active site
696406001096	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
696406001097	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
696406001098	dimer interface [polypeptide binding]; other site
696406001099	active site
696406001100	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
696406001101	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
696406001102	putative active site [active]
696406001103	putative dimer interface [polypeptide binding]; other site
696406001104	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
696406001105	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
696406001106	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041; cl17396
696406001107	RelB antitoxin; Region: RelB; cl01171
696406001108	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
696406001109	NlpC/P60 family; Region: NLPC_P60; pfam00877
696406001110	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG1943
696406001111	Flagellar biosynthesis pathway, component FlhA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlhA; COG1298
696406001112	FHIPEP family; Region: FHIPEP; pfam00771
696406001113	hypothetical protein; Validated; Region: PRK06778
696406001114	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
696406001115	ligand binding site [chemical binding]; other site
696406001116	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
696406001117	active site
696406001118	DNA polymerase IV; Validated; Region: PRK02406
696406001119	DNA binding site [nucleotide binding]
696406001120	putative antitoxin of the YafO-YafN toxin-antitoxin system; Provisional; Region: PRK09778
696406001121	putative toxin YafO; Provisional; Region: PRK09885
696406001122	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
696406001123	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
696406001124	Coenzyme A binding pocket [chemical binding]; other site
696406001125	Uncharacterized protein family UPF0027; Region: UPF0027; cl17455
696406001126	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
696406001127	peptide chain release factor-like protein; Reviewed; Region: prfH; PRK08179
696406001128	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
696406001129	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
696406001130	metal binding site [ion binding]; metal-binding site
696406001131	dimer interface [polypeptide binding]; other site
696406001132	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
696406001133	active site
696406001134	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
696406001135	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
696406001136	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
696406001137	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
696406001138	trimer interface [polypeptide binding]; other site
696406001139	eyelet of channel; other site
696406001140	gamma-glutamyl kinase; Provisional; Region: PRK05429
696406001141	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
696406001142	nucleotide binding site [chemical binding]; other site
696406001143	homotetrameric interface [polypeptide binding]; other site
696406001144	putative phosphate binding site [ion binding]; other site
696406001145	putative allosteric binding site; other site
696406001146	PUA domain; Region: PUA; pfam01472
696406001147	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
696406001148	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
696406001149	putative catalytic cysteine [active]
696406001150	integrase; Provisional; Region: int; PHA02601
696406001151	P22-like integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial and phage integrases, including those similar to phage P22-like integrases, DLP12 and APSE-1; Region: INT_P22_C; cd01192
696406001152	Int/Topo IB signature motif; other site
696406001153	Predicted hydrolases of HD superfamily [General function prediction only]; Region: COG1896
696406001154	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
696406001155	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
696406001156	Catalytic site [active]
696406001157	Uncharacterized protein conserved in bacteria, prophage-related [Function unknown]; Region: COG4197
696406001158	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
696406001159	DNA-binding site [nucleotide binding]; DNA binding site
696406001160	PerC transcriptional activator; Region: PerC; pfam06069
696406001161	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
696406001162	Endodeoxyribonuclease RusA; Region: RusA; pfam05866
696406001163	KilA-N domain; Region: KilA-N; pfam04383
696406001164	Protein of unknown function (DUF968); Region: DUF968; pfam06147
696406001165	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
696406001166	Caspase domain; Region: Peptidase_C14; pfam00656
696406001167	Phage holin family (Lysis protein S); Region: Phage_holin_3; cl04938
696406001168	The lysozyme from bacteriophage lambda hydrolyses the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc), as do other lysozymes.  But unlike other lysozymes, bacteriophage lambda does not produce a reducing...; Region: bacteriophage_lambda_lysozyme; cd00736
696406001169	N-acetyl-D-glucosamine binding site [chemical binding]; other site
696406001170	catalytic residue [active]
696406001171	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
696406001172	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
696406001173	active site
696406001174	Phage terminase, small subunit; Region: Terminase_4; pfam05119
696406001175	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
696406001176	Phage-related protein [Function unknown]; Region: COG4695
696406001177	Phage portal protein; Region: Phage_portal; pfam04860
696406001178	Caudovirus prohead protease; Region: Peptidase_U35; cl01521
696406001179	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
696406001180	Phage capsid family; Region: Phage_capsid; pfam05065
696406001181	Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054
696406001182	oligomerization interface [polypeptide binding]; other site
696406001183	Phage head-tail joining protein; Region: Phage_H_T_join; pfam05521
696406001184	Protein of unknown function (DUF2635); Region: DUF2635; pfam10948
696406001185	Mu-like prophage tail sheath protein gpL [General function prediction only]; Region: COG4386
696406001186	Phage tail sheath protein; Region: Phage_sheath_1; pfam04984
696406001187	Phage tail tube protein; Region: Tail_tube; pfam10618
696406001188	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
696406001189	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
696406001190	Catalytic domain of glycoside hydrolase (GH) families 38 and 57, lactam utilization protein LamB/YcsF family proteins, YdjC-family proteins, and similar proteins; Region: GH38-57_N_LamB_YdjC_SF; cl17191
696406001191	tRNA_anti-like; Region: tRNA_anti-like; pfam12869
696406001192	Mu-like prophage DNA circulation protein [General function prediction only]; Region: COG4228
696406001193	DNA circulation protein N-terminus; Region: DNA_circ_N; pfam07157
696406001194	Mu-like prophage tail protein gpP [General function prediction only]; Region: COG4379
696406001195	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
696406001196	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
696406001197	Bacteriophage Mu Gp45 protein; Region: Phage_Mu_Gp45; pfam06890
696406001198	Phage protein GP46; Region: GP46; pfam07409
696406001199	Uncharacterized homolog of phage Mu protein gp47 [Function unknown]; Region: XkdT; COG3299
696406001200	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3778
696406001201	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
696406001202	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
696406001203	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
696406001204	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
696406001205	catalytic residues [active]
696406001206	catalytic nucleophile [active]
696406001207	Presynaptic Site I dimer interface [polypeptide binding]; other site
696406001208	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
696406001209	Synaptic Flat tetramer interface [polypeptide binding]; other site
696406001210	Synaptic Site I dimer interface [polypeptide binding]; other site
696406001211	DNA binding site [nucleotide binding]
696406001212	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
696406001213	DNA-binding interface [nucleotide binding]; DNA binding site
696406001214	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
696406001215	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
696406001216	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
696406001217	XdhC Rossmann domain; Region: XdhC_C; pfam13478
696406001218	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
696406001219	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
696406001220	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
696406001221	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]; Region: CoxM; COG1319
696406001222	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; smart01092
696406001223	aldehyde oxidoreductase 2Fe-2S subunit; Provisional; Region: PRK11433
696406001224	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2; pfam00111
696406001225	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
696406001226	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
696406001227	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
696406001228	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
696406001229	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
696406001230	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
696406001231	DNA binding residues [nucleotide binding]
696406001232	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
696406001233	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
696406001234	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
696406001235	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
696406001236	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
696406001237	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
696406001238	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
696406001239	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
696406001240	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406001241	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
696406001242	Predicted membrane protein [Function unknown]; Region: COG3059
696406001243	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
696406001244	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK08010
696406001245	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
696406001246	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
696406001247	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
696406001248	Cupin; Region: Cupin_6; pfam12852
696406001249	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
696406001250	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406001251	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
696406001252	Cysteine-rich domain; Region: CCG; pfam02754
696406001253	Cysteine-rich domain; Region: CCG; pfam02754
696406001254	iron-sulfur cluster-binding protein; Region: TIGR00273
696406001255	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
696406001256	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
696406001257	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
696406001258	Uncharacterized conserved protein [Function unknown]; Region: COG1556
696406001259	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
696406001260	choline dehydrogenase; Validated; Region: PRK02106
696406001261	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
696406001262	betaine aldehyde dehydrogenase; Provisional; Region: PRK13252
696406001263	NAD+-dependent 4-trimethylaminobutyraldehyde dehydrogenase, ALDH family 9A1; Region: ALDH_F9_TMBADH; cd07090
696406001264	tetrameric interface [polypeptide binding]; other site
696406001265	NAD binding site [chemical binding]; other site
696406001266	catalytic residues [active]
696406001267	transcriptional regulator BetI; Validated; Region: PRK00767
696406001268	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
696406001269	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
696406001270	choline transport protein BetT; Provisional; Region: PRK09928
696406001271	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
696406001272	DNA binding residues [nucleotide binding]
696406001273	dimerization interface [polypeptide binding]; other site
696406001274	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
696406001275	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
696406001276	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406001277	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
696406001278	dimerization interface [polypeptide binding]; other site
696406001279	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
696406001280	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
696406001281	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
696406001282	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
696406001283	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
696406001284	Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Region: SucD; COG0074
696406001285	CoA binding domain; Region: CoA_binding; pfam02629
696406001286	CoA-ligase; Region: Ligase_CoA; pfam00549
696406001287	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
696406001288	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
696406001289	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
696406001290	putative substrate binding site [chemical binding]; other site
696406001291	nucleotide binding site [chemical binding]; other site
696406001292	nucleotide binding site [chemical binding]; other site
696406001293	homodimer interface [polypeptide binding]; other site
696406001294	putative deaminase; Validated; Region: PRK06846
696406001295	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
696406001296	active site
696406001297	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
696406001298	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
696406001299	putative NAD(P) binding site [chemical binding]; other site
696406001300	putative substrate binding site [chemical binding]; other site
696406001301	catalytic Zn binding site [ion binding]; other site
696406001302	structural Zn binding site [ion binding]; other site
696406001303	dimer interface [polypeptide binding]; other site
696406001304	The Resistance to Homoserine/Threonine (RhtB) Family protein; Region: 2A76; TIGR00949
696406001305	hypothetical protein; Provisional; Region: PRK09929
696406001306	propionate catabolism operon regulatory protein PrpR; Provisional; Region: PRK15424
696406001307	Propionate catabolism activator; Region: PrpR_N; pfam06506
696406001308	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406001309	Walker A motif; other site
696406001310	ATP binding site [chemical binding]; other site
696406001311	Walker B motif; other site
696406001312	arginine finger; other site
696406001313	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
696406001314	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
696406001315	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
696406001316	tetramer interface [polypeptide binding]; other site
696406001317	active site
696406001318	Mg2+/Mn2+ binding site [ion binding]; other site
696406001319	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
696406001320	Subgroup of Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS)...; Region: Ec2MCS_like_1; cd06117
696406001321	dimer interface [polypeptide binding]; other site
696406001322	active site
696406001323	citrylCoA binding site [chemical binding]; other site
696406001324	oxalacetate/citrate binding site [chemical binding]; other site
696406001325	coenzyme A binding site [chemical binding]; other site
696406001326	catalytic triad [active]
696406001327	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
696406001328	2-methylcitrate dehydratase; Region: prpD; TIGR02330
696406001329	propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524
696406001330	Propionyl-CoA synthetase (PrpE); Region: PrpE; cd05967
696406001331	acyl-activating enzyme (AAE) consensus motif; other site
696406001332	putative AMP binding site [chemical binding]; other site
696406001333	putative active site [active]
696406001334	putative CoA binding site [chemical binding]; other site
696406001335	nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; Region: SLC-NCS1sbd_CobB-like; cd11484
696406001336	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
696406001337	Na binding site [ion binding]; other site
696406001338	putative substrate binding site [chemical binding]; other site
696406001339	cytosine deaminase; Provisional; Region: PRK09230
696406001340	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
696406001341	active site
696406001342	DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242
696406001343	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406001344	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator CynR, contains the type 2 periplasmic binding fold; Region: PBP2_CynR; cd08425
696406001345	dimerization interface [polypeptide binding]; other site
696406001346	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
696406001347	active site clefts [active]
696406001348	zinc binding site [ion binding]; other site
696406001349	dimer interface [polypeptide binding]; other site
696406001350	Cyanate lyase [Inorganic ion transport and metabolism]; Region: CynS; COG1513
696406001351	Cyanase C-terminal domain. Cyanase (Cyanate lyase) is responsible for the hydrolysis of cyanate.  It catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. This allows organisms that possess the enzyme to overcome the...; Region: Cyanase_C; cd00559
696406001352	oligomer interface [polypeptide binding]; other site
696406001353	active site
696406001354	putative cyanate transporter; Provisional; Region: cynX; PRK09705
696406001355	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406001356	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
696406001357	putative CoA binding site [chemical binding]; other site
696406001358	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
696406001359	active site
696406001360	substrate binding site [chemical binding]; other site
696406001361	trimer interface [polypeptide binding]; other site
696406001362	LacY proton/sugar symporter; Region: LacY_symp; pfam01306
696406001363	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406001364	putative substrate translocation pore; other site
696406001365	beta-D-galactosidase; Reviewed; Region: lacZ; PRK09525
696406001366	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
696406001367	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
696406001368	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
696406001369	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
696406001370	lac repressor; Reviewed; Region: lacI; PRK09526
696406001371	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
696406001372	DNA binding site [nucleotide binding]
696406001373	domain linker motif; other site
696406001374	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
696406001375	ligand binding site [chemical binding]; other site
696406001376	dimerization interface (open form) [polypeptide binding]; other site
696406001377	dimerization interface (closed form) [polypeptide binding]; other site
696406001378	DNA-binding transcriptional activator MhpR; Provisional; Region: PRK09834
696406001379	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
696406001380	Bacterial transcriptional regulator; Region: IclR; pfam01614
696406001381	3-(3-hydroxyphenyl)propionate hydroxylase; Validated; Region: mhpA; PRK06183
696406001382	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
696406001383	Subunit B of the Class III Extradiol ring-cleavage dioxygenase, 2,3-dihydroxyphenylpropionate 1,2-dioxygenase (MhpB), which catalyzes the oxidization and subsequent ring-opening of 2,3-dihydroxyphenylpropionate; Region: MhpB_like; cd07365
696406001384	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
696406001385	putative active site [active]
696406001386	Fe(II) binding site [ion binding]; other site
696406001387	putative dimer interface [polypeptide binding]; other site
696406001388	putative tetramer interface [polypeptide binding]; other site
696406001389	2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; Region: biphenyl_bphD; TIGR03343
696406001390	methyl indole-3-acetate methyltransferase; Region: PLN02211; cl17657
696406001391	2-keto-4-pentenoate hydratase; Provisional; Region: mhpD; PRK11342
696406001392	acetaldehyde dehydrogenase; Validated; Region: PRK08300
696406001393	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
696406001394	Prokaryotic acetaldehyde dehydrogenase, dimerisation; Region: AcetDehyd-dimer; pfam09290
696406001395	4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase,; Validated; Region: PRK08195
696406001396	4-hydroxy-2-oxovalerate aldolase, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_HOA; cd07943
696406001397	active site
696406001398	catalytic residues [active]
696406001399	metal binding site [ion binding]; metal-binding site
696406001400	DmpG-like communication domain; Region: DmpG_comm; pfam07836
696406001401	putative 3-hydroxyphenylpropionic transporter MhpT; Provisional; Region: PRK11551
696406001402	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406001403	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406001404	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
696406001405	S-formylglutathione hydrolase; Region: PLN02442
696406001406	S-formylglutathione hydrolase; Region: PLN02442
696406001407	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
696406001408	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
696406001409	substrate binding site [chemical binding]; other site
696406001410	catalytic Zn binding site [ion binding]; other site
696406001411	NAD binding site [chemical binding]; other site
696406001412	structural Zn binding site [ion binding]; other site
696406001413	dimer interface [polypeptide binding]; other site
696406001414	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
696406001415	putative metal binding site [ion binding]; other site
696406001416	putative homodimer interface [polypeptide binding]; other site
696406001417	putative homotetramer interface [polypeptide binding]; other site
696406001418	putative homodimer-homodimer interface [polypeptide binding]; other site
696406001419	putative allosteric switch controlling residues; other site
696406001420	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
696406001421	putative trimer interface [polypeptide binding]; other site
696406001422	putative CoA binding site [chemical binding]; other site
696406001423	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
696406001424	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
696406001425	DXD motif; other site
696406001426	Uncharacterized proteins, LmbE homologs [Function unknown]; Region: COG2120
696406001427	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
696406001428	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
696406001429	membrane-bound complex binding site; other site
696406001430	hinge residues; other site
696406001431	taurine transporter ATP-binding subunit; Provisional; Region: tauB; PRK11248
696406001432	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
696406001433	Walker A/P-loop; other site
696406001434	ATP binding site [chemical binding]; other site
696406001435	Q-loop/lid; other site
696406001436	ABC transporter signature motif; other site
696406001437	Walker B; other site
696406001438	D-loop; other site
696406001439	H-loop/switch region; other site
696406001440	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
696406001441	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406001442	dimer interface [polypeptide binding]; other site
696406001443	conserved gate region; other site
696406001444	putative PBP binding loops; other site
696406001445	ABC-ATPase subunit interface; other site
696406001446	Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175
696406001447	taurine dioxygenase; Reviewed; Region: tauD; PRK09553
696406001448	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
696406001449	dimer interface [polypeptide binding]; other site
696406001450	active site
696406001451	Schiff base residues; other site
696406001452	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
696406001453	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cd00253
696406001454	Autotransporter beta-domain; Region: Autotransporter; pfam03797
696406001455	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
696406001456	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
696406001457	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
696406001458	microcin B17 transporter; Reviewed; Region: PRK11098
696406001459	Protein of unknown function (DUF1615); Region: DUF1615; pfam07759
696406001460	Protein of unknown function (DUF2755); Region: DUF2755; pfam10954
696406001461	Protein of unknown function (DUF2754); Region: DUF2754; pfam10953
696406001462	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
696406001463	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
696406001464	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
696406001465	anti-RssB factor; Provisional; Region: PRK10244
696406001466	alkaline phosphatase; Provisional; Region: PRK10518
696406001467	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016
696406001468	dimer interface [polypeptide binding]; other site
696406001469	active site
696406001470	hypothetical protein; Provisional; Region: PRK11505
696406001471	psiF repeat; Region: PsiF_repeat; pfam07769
696406001472	psiF repeat; Region: PsiF_repeat; pfam07769
696406001473	diguanylate cyclase AdrA; Provisional; Region: adrA; PRK10245
696406001474	MASE2 domain; Region: MASE2; pfam05230
696406001475	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
696406001476	metal binding site [ion binding]; metal-binding site
696406001477	active site
696406001478	I-site; other site
696406001479	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
696406001480	pyrroline-5-carboxylate reductase; Region: PLN02688
696406001481	hypothetical protein; Validated; Region: PRK00124
696406001482	Shikimate kinase; Region: SKI; pfam01202
696406001483	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
696406001484	magnesium binding site [ion binding]; other site
696406001485	putative shikimate binding site; other site
696406001486	hypothetical protein; Provisional; Region: PRK10380
696406001487	hypothetical protein; Provisional; Region: PRK10481
696406001488	hypothetical protein; Provisional; Region: PRK10579
696406001489	Protein of unknown function (DUF2773); Region: DUF2773; pfam10971
696406001490	DNA recombination-dependent growth factor C [DNA replication, recombination, and repair]; Region: RdgC; COG2974
696406001491	fructokinase; Reviewed; Region: PRK09557
696406001492	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
696406001493	nucleotide binding site [chemical binding]; other site
696406001494	MFS transport protein AraJ; Provisional; Region: PRK10091
696406001495	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406001496	putative substrate translocation pore; other site
696406001497	exonuclease subunit SbcC; Provisional; Region: PRK10246
696406001498	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
696406001499	Walker A/P-loop; other site
696406001500	ATP binding site [chemical binding]; other site
696406001501	Q-loop/lid; other site
696406001502	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
696406001503	ABC transporter signature motif; other site
696406001504	Walker B; other site
696406001505	D-loop; other site
696406001506	H-loop/switch region; other site
696406001507	exonuclease subunit SbcD; Provisional; Region: PRK10966
696406001508	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
696406001509	active site
696406001510	metal binding site [ion binding]; metal-binding site
696406001511	DNA binding site [nucleotide binding]
696406001512	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
696406001513	transcriptional regulator PhoB; Provisional; Region: PRK10161
696406001514	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406001515	active site
696406001516	phosphorylation site [posttranslational modification]
696406001517	intermolecular recognition site; other site
696406001518	dimerization interface [polypeptide binding]; other site
696406001519	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
696406001520	DNA binding site [nucleotide binding]
696406001521	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
696406001522	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
696406001523	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
696406001524	putative active site [active]
696406001525	heme pocket [chemical binding]; other site
696406001526	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
696406001527	dimer interface [polypeptide binding]; other site
696406001528	phosphorylation site [posttranslational modification]
696406001529	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406001530	ATP binding site [chemical binding]; other site
696406001531	Mg2+ binding site [ion binding]; other site
696406001532	G-X-G motif; other site
696406001533	branched-chain amino acid transport system 2 carrier protein BrnQ; Provisional; Region: PRK15433
696406001534	putative proline-specific permease; Provisional; Region: proY; PRK10580
696406001535	maltodextrin glucosidase; Provisional; Region: PRK10785
696406001536	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
696406001537	homodimer interface [polypeptide binding]; other site
696406001538	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
696406001539	active site
696406001540	homodimer interface [polypeptide binding]; other site
696406001541	catalytic site [active]
696406001542	acyl carrier protein phosphodiesterase; Provisional; Region: PRK10045
696406001543	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
696406001544	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
696406001545	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
696406001546	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
696406001547	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
696406001548	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
696406001549	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
696406001550	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
696406001551	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
696406001552	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
696406001553	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
696406001554	Protein export membrane protein; Region: SecD_SecF; pfam02355
696406001555	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
696406001556	active site
696406001557	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
696406001558	hypothetical protein; Provisional; Region: PRK11530
696406001559	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
696406001560	ATP cone domain; Region: ATP-cone; pfam03477
696406001561	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
696406001562	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
696406001563	catalytic motif [active]
696406001564	Zn binding site [ion binding]; other site
696406001565	riboflavin-specific deaminase C-terminal domain; Region: ribD_Cterm; TIGR00227
696406001566	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
696406001567	homopentamer interface [polypeptide binding]; other site
696406001568	active site
696406001569	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
696406001570	putative RNA binding site [nucleotide binding]; other site
696406001571	thiamine monophosphate kinase; Provisional; Region: PRK05731
696406001572	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
696406001573	ATP binding site [chemical binding]; other site
696406001574	dimerization interface [polypeptide binding]; other site
696406001575	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
696406001576	tetramer interfaces [polypeptide binding]; other site
696406001577	binuclear metal-binding site [ion binding]; other site
696406001578	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
696406001579	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
696406001580	active site
696406001581	catalytic tetrad [active]
696406001582	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
696406001583	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
696406001584	TPP-binding site; other site
696406001585	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
696406001586	PYR/PP interface [polypeptide binding]; other site
696406001587	dimer interface [polypeptide binding]; other site
696406001588	TPP binding site [chemical binding]; other site
696406001589	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
696406001590	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
696406001591	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
696406001592	substrate binding pocket [chemical binding]; other site
696406001593	chain length determination region; other site
696406001594	substrate-Mg2+ binding site; other site
696406001595	catalytic residues [active]
696406001596	aspartate-rich region 1; other site
696406001597	active site lid residues [active]
696406001598	aspartate-rich region 2; other site
696406001599	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
696406001600	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
696406001601	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
696406001602	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
696406001603	Ligand Binding Site [chemical binding]; other site
696406001604	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
696406001605	active site residue [active]
696406001606	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
696406001607	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
696406001608	conserved cys residue [active]
696406001609	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
696406001610	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
696406001611	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
696406001612	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
696406001613	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
696406001614	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406001615	Major Facilitator Superfamily; Region: MFS_1; pfam07690
696406001616	putative substrate translocation pore; other site
696406001617	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
696406001618	UbiA prenyltransferase family; Region: UbiA; pfam01040
696406001619	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
696406001620	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
696406001621	Subunit I/III interface [polypeptide binding]; other site
696406001622	Subunit III/IV interface [polypeptide binding]; other site
696406001623	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
696406001624	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
696406001625	D-pathway; other site
696406001626	Putative ubiquinol binding site [chemical binding]; other site
696406001627	Low-spin heme (heme b) binding site [chemical binding]; other site
696406001628	Putative water exit pathway; other site
696406001629	Binuclear center (heme o3/CuB) [ion binding]; other site
696406001630	K-pathway; other site
696406001631	Putative proton exit pathway; other site
696406001632	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
696406001633	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
696406001634	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
696406001635	muropeptide transporter; Reviewed; Region: ampG; PRK11902
696406001636	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406001637	putative substrate translocation pore; other site
696406001638	hypothetical protein; Provisional; Region: PRK11627
696406001639	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
696406001640	transcriptional regulator BolA; Provisional; Region: PRK11628
696406001641	trigger factor; Provisional; Region: tig; PRK01490
696406001642	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
696406001643	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
696406001644	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
696406001645	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
696406001646	oligomer interface [polypeptide binding]; other site
696406001647	active site residues [active]
696406001648	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
696406001649	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
696406001650	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406001651	Walker A motif; other site
696406001652	ATP binding site [chemical binding]; other site
696406001653	Walker B motif; other site
696406001654	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
696406001655	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
696406001656	Found in ATP-dependent protease La (LON); Region: LON; smart00464
696406001657	Found in ATP-dependent protease La (LON); Region: LON; smart00464
696406001658	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406001659	Walker A motif; other site
696406001660	ATP binding site [chemical binding]; other site
696406001661	Walker B motif; other site
696406001662	arginine finger; other site
696406001663	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
696406001664	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
696406001665	IHF dimer interface [polypeptide binding]; other site
696406001666	IHF - DNA interface [nucleotide binding]; other site
696406001667	periplasmic folding chaperone; Provisional; Region: PRK10788
696406001668	SurA N-terminal domain; Region: SurA_N_3; cl07813
696406001669	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
696406001670	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
696406001671	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
696406001672	active site
696406001673	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
696406001674	Ligand Binding Site [chemical binding]; other site
696406001675	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
696406001676	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
696406001677	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
696406001678	thiamin pyrimidine pyrophosphate hydrolase; Provisional; Region: PRK15126
696406001679	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696406001680	active site
696406001681	motif I; other site
696406001682	motif II; other site
696406001683	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
696406001684	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
696406001685	putative DNA binding site [nucleotide binding]; other site
696406001686	putative Zn2+ binding site [ion binding]; other site
696406001687	AsnC family; Region: AsnC_trans_reg; pfam01037
696406001688	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
696406001689	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
696406001690	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
696406001691	Walker A/P-loop; other site
696406001692	ATP binding site [chemical binding]; other site
696406001693	Q-loop/lid; other site
696406001694	ABC transporter signature motif; other site
696406001695	Walker B; other site
696406001696	D-loop; other site
696406001697	H-loop/switch region; other site
696406001698	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
696406001699	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
696406001700	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
696406001701	Walker A/P-loop; other site
696406001702	ATP binding site [chemical binding]; other site
696406001703	Q-loop/lid; other site
696406001704	ABC transporter signature motif; other site
696406001705	Walker B; other site
696406001706	D-loop; other site
696406001707	H-loop/switch region; other site
696406001708	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
696406001709	Nitrogen regulatory protein P-II; Region: P-II; smart00938
696406001710	ammonium transporter; Provisional; Region: PRK10666
696406001711	acyl-CoA thioesterase II; Provisional; Region: PRK10526
696406001712	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
696406001713	active site
696406001714	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
696406001715	catalytic triad [active]
696406001716	dimer interface [polypeptide binding]; other site
696406001717	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
696406001718	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
696406001719	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
696406001720	DNA binding site [nucleotide binding]
696406001721	active site
696406001722	Uncharacterized conserved protein [Function unknown]; Region: COG5507
696406001723	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
696406001724	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
696406001725	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
696406001726	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
696406001727	maltose O-acetyltransferase; Provisional; Region: PRK10092
696406001728	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
696406001729	active site
696406001730	substrate binding site [chemical binding]; other site
696406001731	trimer interface [polypeptide binding]; other site
696406001732	CoA binding site [chemical binding]; other site
696406001733	gene expression modulator; Provisional; Region: PRK10945
696406001734	Biofilm formation regulator YbaJ; Region: YbaJ; pfam10757
696406001735	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
696406001736	Protein export membrane protein; Region: SecD_SecF; cl14618
696406001737	Protein export membrane protein; Region: SecD_SecF; cl14618
696406001738	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
696406001739	HlyD family secretion protein; Region: HlyD_3; pfam13437
696406001740	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
696406001741	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
696406001742	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
696406001743	hypothetical protein; Provisional; Region: PRK11281
696406001744	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
696406001745	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
696406001746	Mechanosensitive ion channel; Region: MS_channel; pfam00924
696406001747	hypothetical protein; Provisional; Region: PRK11038
696406001748	primosomal replication protein N''; Provisional; Region: PRK10093
696406001749	hypothetical protein; Provisional; Region: PRK10527
696406001750	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
696406001751	active site
696406001752	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406001753	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
696406001754	Walker A motif; other site
696406001755	ATP binding site [chemical binding]; other site
696406001756	Walker B motif; other site
696406001757	DNA polymerase III subunit delta'; Validated; Region: PRK08485
696406001758	arginine finger; other site
696406001759	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
696406001760	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
696406001761	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
696406001762	hypothetical protein; Validated; Region: PRK00153
696406001763	Recombinational DNA repair protein (RecF pathway) [DNA replication, recombination, and repair]; Region: RecR; COG0353
696406001764	RecR protein; Region: RecR; pfam02132
696406001765	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
696406001766	putative active site [active]
696406001767	putative metal-binding site [ion binding]; other site
696406001768	tetramer interface [polypeptide binding]; other site
696406001769	heat shock protein 90; Provisional; Region: PRK05218
696406001770	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406001771	ATP binding site [chemical binding]; other site
696406001772	Mg2+ binding site [ion binding]; other site
696406001773	G-X-G motif; other site
696406001774	adenylate kinase; Reviewed; Region: adk; PRK00279
696406001775	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
696406001776	AMP-binding site [chemical binding]; other site
696406001777	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
696406001778	ferrochelatase; Region: hemH; TIGR00109
696406001779	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
696406001780	C-terminal domain interface [polypeptide binding]; other site
696406001781	active site
696406001782	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
696406001783	active site
696406001784	N-terminal domain interface [polypeptide binding]; other site
696406001785	acetyl esterase; Provisional; Region: PRK10162
696406001786	inosine/guanosine kinase; Provisional; Region: PRK15074
696406001787	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
696406001788	putative cation:proton antiport protein; Provisional; Region: PRK10669
696406001789	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
696406001790	TrkA-N domain; Region: TrkA_N; pfam02254
696406001791	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406001792	Major Facilitator Superfamily; Region: MFS_1; pfam07690
696406001793	putative substrate translocation pore; other site
696406001794	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
696406001795	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
696406001796	active site
696406001797	metal binding site [ion binding]; metal-binding site
696406001798	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
696406001799	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
696406001800	putative deacylase active site [active]
696406001801	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3735
696406001802	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
696406001803	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
696406001804	non-specific DNA binding site [nucleotide binding]; other site
696406001805	salt bridge; other site
696406001806	sequence-specific DNA binding site [nucleotide binding]; other site
696406001807	copper exporting ATPase; Provisional; Region: copA; PRK10671
696406001808	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
696406001809	metal-binding site [ion binding]
696406001810	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
696406001811	metal-binding site [ion binding]
696406001812	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
696406001813	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696406001814	motif II; other site
696406001815	glutaminase; Reviewed; Region: PRK12356
696406001816	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
696406001817	amino acid transporter; Region: 2A0306; TIGR00909
696406001818	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
696406001819	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
696406001820	DNA binding residues [nucleotide binding]
696406001821	dimer interface [polypeptide binding]; other site
696406001822	copper binding site [ion binding]; other site
696406001823	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
696406001824	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
696406001825	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
696406001826	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
696406001827	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
696406001828	Walker A/P-loop; other site
696406001829	ATP binding site [chemical binding]; other site
696406001830	Q-loop/lid; other site
696406001831	ABC transporter signature motif; other site
696406001832	Walker B; other site
696406001833	D-loop; other site
696406001834	H-loop/switch region; other site
696406001835	Uncharacterized protein family (UPF0014); Region: UPF0014; pfam03649
696406001836	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
696406001837	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
696406001838	oxidoreductase; Provisional; Region: PRK08017
696406001839	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
696406001840	NADP binding site [chemical binding]; other site
696406001841	active site
696406001842	steroid binding site; other site
696406001843	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
696406001844	active site
696406001845	catalytic triad [active]
696406001846	oxyanion hole [active]
696406001847	switch loop; other site
696406001848	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
696406001849	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
696406001850	Walker A/P-loop; other site
696406001851	ATP binding site [chemical binding]; other site
696406001852	Q-loop/lid; other site
696406001853	ABC transporter signature motif; other site
696406001854	Walker B; other site
696406001855	D-loop; other site
696406001856	H-loop/switch region; other site
696406001857	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
696406001858	FtsX-like permease family; Region: FtsX; pfam02687
696406001859	FtsX-like permease family; Region: FtsX; pfam02687
696406001860	PAAR motif; Region: PAAR_motif; cl15808
696406001861	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
696406001862	RHS Repeat; Region: RHS_repeat; pfam05593
696406001863	RHS Repeat; Region: RHS_repeat; pfam05593
696406001864	RHS Repeat; Region: RHS_repeat; pfam05593
696406001865	RHS Repeat; Region: RHS_repeat; pfam05593
696406001866	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
696406001867	RHS Repeat; Region: RHS_repeat; pfam05593
696406001868	RHS Repeat; Region: RHS_repeat; pfam05593
696406001869	RHS protein; Region: RHS; pfam03527
696406001870	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
696406001871	Domain of unknown function (DUF4329); Region: DUF4329; pfam14220
696406001872	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
696406001873	RHS protein; Region: RHS; pfam03527
696406001874	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
696406001875	Winged helix-turn helix; Region: HTH_29; pfam13551
696406001876	Helix-turn-helix domain; Region: HTH_28; pfam13518
696406001877	Predicted ATPase [General function prediction only]; Region: COG2603
696406001878	Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB; Region: RHOD_YbbB; cd01520
696406001879	active site residue [active]
696406001880	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
696406001881	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406001882	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
696406001883	dimerization interface [polypeptide binding]; other site
696406001884	Ureidoglycolate hydrolase [Nucleotide transport and metabolism]; Region: DAL3; COG3194
696406001885	ureidoglycolate hydrolase; Provisional; Region: PRK03606
696406001886	DNA-binding transcriptional repressor AllR; Provisional; Region: PRK10163
696406001887	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
696406001888	Bacterial transcriptional regulator; Region: IclR; pfam01614
696406001889	glyoxylate carboligase; Provisional; Region: PRK11269
696406001890	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
696406001891	PYR/PP interface [polypeptide binding]; other site
696406001892	dimer interface [polypeptide binding]; other site
696406001893	TPP binding site [chemical binding]; other site
696406001894	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
696406001895	Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the...; Region: TPP_Gcl; cd02006
696406001896	TPP-binding site [chemical binding]; other site
696406001897	hydroxypyruvate isomerase; Provisional; Region: PRK09997
696406001898	tartronate semialdehyde reductase; Provisional; Region: PRK15059
696406001899	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
696406001900	nucleobase-cation-symport-1 (NCS1) transporters; solute-binding domain; Region: SLC-NCS1sbd; cd10323
696406001901	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
696406001902	Na binding site [ion binding]; other site
696406001903	substrate binding site [chemical binding]; other site
696406001904	allantoinase; Provisional; Region: PRK08044
696406001905	L-Hydantoinases (L-HYDs) and Allantoinase (ALN); L-Hydantoinases are a member of the dihydropyrimidinase family, which catalyzes the reversible hydrolytic ring opening of dihydropyrimidines and hydantoins (five-membered cyclic diamides used in...; Region: L-HYD_ALN; cd01315
696406001906	active site
696406001907	putative uracil/xanthine transporter; Provisional; Region: PRK11412
696406001908	glycerate kinase II; Provisional; Region: PRK09932
696406001909	Uncharacterized protein, possibly involved in glyoxylate utilization [General function prediction only]; Region: GlxB; COG3257
696406001910	Protein of unknown function (DUF861); Region: Cupin_3; pfam05899
696406001911	Cupin domain; Region: Cupin_2; cl17218
696406001912	allantoate amidohydrolase; Region: AllC; TIGR03176
696406001913	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
696406001914	active site
696406001915	metal binding site [ion binding]; metal-binding site
696406001916	dimer interface [polypeptide binding]; other site
696406001917	ureidoglycolate dehydrogenase; Provisional; Region: PRK15025
696406001918	membrane protein FdrA; Validated; Region: PRK06091
696406001919	CoA binding domain; Region: CoA_binding; pfam02629
696406001920	CoA-ligase; Region: Ligase_CoA; pfam00549
696406001921	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
696406001922	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
696406001923	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
696406001924	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
696406001925	putative substrate binding site [chemical binding]; other site
696406001926	nucleotide binding site [chemical binding]; other site
696406001927	nucleotide binding site [chemical binding]; other site
696406001928	homodimer interface [polypeptide binding]; other site
696406001929	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
696406001930	ATP-grasp domain; Region: ATP-grasp; pfam02222
696406001931	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
696406001932	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
696406001933	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
696406001934	putative active site [active]
696406001935	putative metal binding site [ion binding]; other site
696406001936	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
696406001937	substrate binding site [chemical binding]; other site
696406001938	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
696406001939	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
696406001940	active site
696406001941	HIGH motif; other site
696406001942	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
696406001943	KMSKS motif; other site
696406001944	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
696406001945	tRNA binding surface [nucleotide binding]; other site
696406001946	anticodon binding site; other site
696406001947	Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988
696406001948	ribosome-associated protein; Provisional; Region: PRK11507
696406001949	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
696406001950	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
696406001951	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
696406001952	homodimer interface [polypeptide binding]; other site
696406001953	NADP binding site [chemical binding]; other site
696406001954	substrate binding site [chemical binding]; other site
696406001955	type-1 fimbrial protein subunit A; Provisional; Region: PRK15194
696406001956	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
696406001957	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
696406001958	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
696406001959	outer membrane usher protein FimD; Provisional; Region: PRK15198
696406001960	PapC N-terminal domain; Region: PapC_N; pfam13954
696406001961	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
696406001962	PapC C-terminal domain; Region: PapC_C; pfam13953
696406001963	fimbrial-like adhesin; Provisional; Region: fimH; PRK15199
696406001964	Fimbrial protein; Region: Fimbrial; cl01416
696406001965	transcriptional regulator FimZ; Provisional; Region: PRK09935
696406001966	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406001967	active site
696406001968	phosphorylation site [posttranslational modification]
696406001969	intermolecular recognition site; other site
696406001970	dimerization interface [polypeptide binding]; other site
696406001971	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
696406001972	DNA binding residues [nucleotide binding]
696406001973	dimerization interface [polypeptide binding]; other site
696406001974	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
696406001975	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406001976	hypothetical protein; Provisional; Region: PRK09936
696406001977	bacteriophage N4 receptor, outer membrane subunit; Provisional; Region: PRK09782
696406001978	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
696406001979	TPR motif; other site
696406001980	binding surface
696406001981	Bacteriophage N adsorption protein A C-term; Region: NfrA_C; pfam13283
696406001982	bacteriophage N4 adsorption protein B; Provisional; Region: nfrB; PRK11234
696406001983	active site
696406001984	Glycosyl transferase family group 2; Region: Glyco_trans_2_3; pfam13632
696406001985	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
696406001986	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
696406001987	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
696406001988	Transposase [DNA replication, recombination, and repair]; Region: COG5433
696406001989	Transposase [DNA replication, recombination, and repair]; Region: COG5433
696406001990	PAAR motif; Region: PAAR_motif; pfam05488
696406001991	RHS Repeat; Region: RHS_repeat; cl11982
696406001992	RHS Repeat; Region: RHS_repeat; pfam05593
696406001993	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
696406001994	RHS Repeat; Region: RHS_repeat; pfam05593
696406001995	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
696406001996	RHS Repeat; Region: RHS_repeat; cl11982
696406001997	RHS Repeat; Region: RHS_repeat; pfam05593
696406001998	RHS Repeat; Region: RHS_repeat; cl11982
696406001999	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
696406002000	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
696406002001	Uncharacterized conserved protein [Function unknown]; Region: COG5435
696406002002	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
696406002003	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
696406002004	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
696406002005	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
696406002006	sensor kinase CusS; Provisional; Region: PRK09835
696406002007	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
696406002008	dimerization interface [polypeptide binding]; other site
696406002009	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
696406002010	dimer interface [polypeptide binding]; other site
696406002011	phosphorylation site [posttranslational modification]
696406002012	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406002013	ATP binding site [chemical binding]; other site
696406002014	Mg2+ binding site [ion binding]; other site
696406002015	G-X-G motif; other site
696406002016	DNA-binding transcriptional activator CusR; Provisional; Region: PRK09836
696406002017	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406002018	active site
696406002019	phosphorylation site [posttranslational modification]
696406002020	intermolecular recognition site; other site
696406002021	dimerization interface [polypeptide binding]; other site
696406002022	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
696406002023	DNA binding site [nucleotide binding]
696406002024	copper/silver efflux system outer membrane protein CusC; Provisional; Region: PRK09837
696406002025	periplasmic copper-binding protein; Provisional; Region: PRK09838
696406002026	copper/silver efflux system membrane fusion protein CusB; Provisional; Region: PRK09783
696406002027	HlyD family secretion protein; Region: HlyD_3; pfam13437
696406002028	heavy metal efflux pump, CzcA family; Region: 2A0601; TIGR00914
696406002029	phenylalanine transporter; Provisional; Region: PRK10249
696406002030	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
696406002031	Mechanosensitive ion channel; Region: MS_channel; pfam00924
696406002032	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
696406002033	dimer interface [polypeptide binding]; other site
696406002034	FMN binding site [chemical binding]; other site
696406002035	hypothetical protein; Provisional; Region: PRK10250
696406002036	Protein of unknown function (DUF1158); Region: DUF1158; pfam06643
696406002037	gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516
696406002038	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
696406002039	Hok/gef family; Region: HOK_GEF; pfam01848
696406002040	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
696406002041	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
696406002042	phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex; Provisional; Region: PRK10251
696406002043	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
696406002044	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; cl00500
696406002045	outer membrane receptor FepA; Provisional; Region: PRK13524
696406002046	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
696406002047	N-terminal plug; other site
696406002048	ligand-binding site [chemical binding]; other site
696406002049	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
696406002050	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
696406002051	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
696406002052	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3251
696406002053	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
696406002054	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
696406002055	acyl-activating enzyme (AAE) consensus motif; other site
696406002056	AMP binding site [chemical binding]; other site
696406002057	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
696406002058	LPS O-antigen length regulator; Provisional; Region: PRK10381
696406002059	Chain length determinant protein; Region: Wzz; pfam02706
696406002060	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
696406002061	iron-enterobactin transporter ATP-binding protein; Provisional; Region: PRK10253
696406002062	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
696406002063	Walker A/P-loop; other site
696406002064	ATP binding site [chemical binding]; other site
696406002065	Q-loop/lid; other site
696406002066	ABC transporter signature motif; other site
696406002067	Walker B; other site
696406002068	D-loop; other site
696406002069	H-loop/switch region; other site
696406002070	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
696406002071	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
696406002072	ABC-ATPase subunit  interface; other site
696406002073	dimer interface [polypeptide binding]; other site
696406002074	putative PBP binding regions; other site
696406002075	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
696406002076	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
696406002077	ABC-ATPase subunit  interface; other site
696406002078	dimer interface [polypeptide binding]; other site
696406002079	putative PBP binding regions; other site
696406002080	enterobactin exporter EntS; Provisional; Region: PRK10489
696406002081	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406002082	putative substrate translocation pore; other site
696406002083	iron-enterobactin transporter periplasmic binding protein; Provisional; Region: PRK10957
696406002084	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
696406002085	siderophore binding site; other site
696406002086	isochorismate synthase EntC; Provisional; Region: PRK15016
696406002087	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
696406002088	enterobactin synthase subunit E; Provisional; Region: entE; PRK10946
696406002089	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
696406002090	acyl-activating enzyme (AAE) consensus motif; other site
696406002091	active site
696406002092	AMP binding site [chemical binding]; other site
696406002093	substrate binding site [chemical binding]; other site
696406002094	Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013
696406002095	hydrophobic substrate binding pocket; other site
696406002096	Isochorismatase family; Region: Isochorismatase; pfam00857
696406002097	active site
696406002098	conserved cis-peptide bond; other site
696406002099	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
696406002100	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
696406002101	2,3 dihydro-2,3 dihydrozybenzoate dehydrogenases, classical (c) SDRs; Region: DH-DHB-DH_SDR_c; cd05331
696406002102	putative NAD(P) binding site [chemical binding]; other site
696406002103	active site
696406002104	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
696406002105	CoenzymeA binding site [chemical binding]; other site
696406002106	subunit interaction site [polypeptide binding]; other site
696406002107	PHB binding site; other site
696406002108	carbon starvation protein A; Provisional; Region: PRK15015
696406002109	Carbon starvation protein CstA; Region: CstA; pfam02554
696406002110	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
696406002111	Uncharacterized small protein [Function unknown]; Region: COG2879
696406002112	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
696406002113	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
696406002114	putative active site [active]
696406002115	metal binding site [ion binding]; metal-binding site
696406002116	methionine aminotransferase; Validated; Region: PRK09082
696406002117	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
696406002118	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406002119	homodimer interface [polypeptide binding]; other site
696406002120	catalytic residue [active]
696406002121	ParB-like nuclease domain; Region: ParBc; pfam02195
696406002122	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
696406002123	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
696406002124	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
696406002125	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
696406002126	Active Sites [active]
696406002127	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
696406002128	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
696406002129	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406002130	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
696406002131	disulfide isomerase/thiol-disulfide oxidase; Provisional; Region: dsbG; PRK11657
696406002132	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
696406002133	dimerization domain [polypeptide binding]; other site
696406002134	dimer interface [polypeptide binding]; other site
696406002135	catalytic residues [active]
696406002136	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
696406002137	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
696406002138	dimer interface [polypeptide binding]; other site
696406002139	decamer (pentamer of dimers) interface [polypeptide binding]; other site
696406002140	catalytic triad [active]
696406002141	peroxidatic and resolving cysteines [active]
696406002142	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
696406002143	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
696406002144	catalytic residue [active]
696406002145	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
696406002146	catalytic residues [active]
696406002147	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
696406002148	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
696406002149	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
696406002150	Ligand Binding Site [chemical binding]; other site
696406002151	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
696406002152	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
696406002153	NAD binding site [chemical binding]; other site
696406002154	catalytic Zn binding site [ion binding]; other site
696406002155	structural Zn binding site [ion binding]; other site
696406002156	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
696406002157	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
696406002158	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062
696406002159	B1 nucleotide binding pocket [chemical binding]; other site
696406002160	B2 nucleotide binding pocket [chemical binding]; other site
696406002161	CAS motifs; other site
696406002162	active site
696406002163	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
696406002164	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
696406002165	transmembrane helices; other site
696406002166	triphosphoribosyl-dephospho-CoA synthase; Provisional; Region: citG; PRK10096
696406002167	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
696406002168	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
696406002169	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
696406002170	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
696406002171	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
696406002172	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
696406002173	putative active site [active]
696406002174	(T/H)XGH motif; other site
696406002175	sensor histidine kinase DpiB; Provisional; Region: dpiB; PRK15053
696406002176	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
696406002177	putative active site [active]
696406002178	heme pocket [chemical binding]; other site
696406002179	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406002180	ATP binding site [chemical binding]; other site
696406002181	Mg2+ binding site [ion binding]; other site
696406002182	G-X-G motif; other site
696406002183	two-component response regulator DpiA; Provisional; Region: dpiA; PRK10046
696406002184	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406002185	active site
696406002186	phosphorylation site [posttranslational modification]
696406002187	intermolecular recognition site; other site
696406002188	dimerization interface [polypeptide binding]; other site
696406002189	Transcriptional regulator; Region: CitT; pfam12431
696406002190	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
696406002191	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
696406002192	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
696406002193	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
696406002194	DNA-binding site [nucleotide binding]; DNA binding site
696406002195	RNA-binding motif; other site
696406002196	chromosome condensation membrane protein; Provisional; Region: PRK14196
696406002197	Predicted amidohydrolase [General function prediction only]; Region: COG0388
696406002198	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_3; cd07581
696406002199	putative active site [active]
696406002200	catalytic triad [active]
696406002201	putative dimer interface [polypeptide binding]; other site
696406002202	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
696406002203	lipoyl synthase; Provisional; Region: PRK05481
696406002204	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
696406002205	FeS/SAM binding site; other site
696406002206	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
696406002207	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406002208	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
696406002209	substrate binding pocket [chemical binding]; other site
696406002210	dimerization interface [polypeptide binding]; other site
696406002211	lipoate-protein ligase B; Provisional; Region: PRK14342
696406002212	hypothetical protein; Provisional; Region: PRK04998
696406002213	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
696406002214	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
696406002215	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
696406002216	rare lipoprotein A; Provisional; Region: PRK10672
696406002217	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
696406002218	Sporulation related domain; Region: SPOR; pfam05036
696406002219	cell wall shape-determining protein; Provisional; Region: PRK10794
696406002220	penicillin-binding protein 2; Provisional; Region: PRK10795
696406002221	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
696406002222	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
696406002223	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
696406002224	ribosome-associated protein; Provisional; Region: PRK11538
696406002225	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
696406002226	catalytic core [active]
696406002227	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
696406002228	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
696406002229	active site
696406002230	(T/H)XGH motif; other site
696406002231	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
696406002232	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
696406002233	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
696406002234	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
696406002235	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
696406002236	HIGH motif; other site
696406002237	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
696406002238	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
696406002239	active site
696406002240	KMSKS motif; other site
696406002241	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
696406002242	tRNA binding surface [nucleotide binding]; other site
696406002243	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
696406002244	hypothetical protein; Provisional; Region: PRK11032
696406002245	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
696406002246	Sel1-like repeats; Region: SEL1; smart00671
696406002247	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
696406002248	Sel1-like repeats; Region: SEL1; smart00671
696406002249	Sel1-like repeats; Region: SEL1; smart00671
696406002250	Sel1-like repeats; Region: SEL1; smart00671
696406002251	Sel1-like repeats; Region: SEL1; smart00671
696406002252	Sel1-like repeats; Region: SEL1; smart00671
696406002253	Sel1-like repeats; Region: SEL1; smart00671
696406002254	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
696406002255	DnaJ molecular chaperone homology domain; Region: DnaJ; smart00271
696406002256	HSP70 interaction site [polypeptide binding]; other site
696406002257	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
696406002258	Sel1-like repeats; Region: SEL1; smart00671
696406002259	Sel1-like repeats; Region: SEL1; smart00671
696406002260	Sel1-like repeats; Region: SEL1; smart00671
696406002261	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
696406002262	Molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: DnaK; COG0443
696406002263	Nucleotide-binding domain of Escherichia coli HscC and similar proteins; Region: HscC_like_NBD; cd10235
696406002264	nucleotide binding site [chemical binding]; other site
696406002265	putative NEF/HSP70 interaction site [polypeptide binding]; other site
696406002266	SBD interface [polypeptide binding]; other site
696406002267	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
696406002268	active site
696406002269	tetramer interface [polypeptide binding]; other site
696406002270	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
696406002271	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
696406002272	Walker A/P-loop; other site
696406002273	ATP binding site [chemical binding]; other site
696406002274	Q-loop/lid; other site
696406002275	ABC transporter signature motif; other site
696406002276	Walker B; other site
696406002277	D-loop; other site
696406002278	H-loop/switch region; other site
696406002279	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
696406002280	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406002281	dimer interface [polypeptide binding]; other site
696406002282	conserved gate region; other site
696406002283	putative PBP binding loops; other site
696406002284	ABC-ATPase subunit interface; other site
696406002285	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
696406002286	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406002287	dimer interface [polypeptide binding]; other site
696406002288	conserved gate region; other site
696406002289	putative PBP binding loops; other site
696406002290	ABC-ATPase subunit interface; other site
696406002291	glutamate and aspartate transporter subunit; Provisional; Region: PRK10797
696406002292	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
696406002293	substrate binding pocket [chemical binding]; other site
696406002294	membrane-bound complex binding site; other site
696406002295	hinge residues; other site
696406002296	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
696406002297	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
696406002298	putative active site [active]
696406002299	catalytic triad [active]
696406002300	putative dimer interface [polypeptide binding]; other site
696406002301	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
696406002302	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
696406002303	Transporter associated domain; Region: CorC_HlyC; smart01091
696406002304	metal-binding heat shock protein; Provisional; Region: PRK00016
696406002305	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
696406002306	PhoH-like protein; Region: PhoH; pfam02562
696406002307	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
696406002308	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
696406002309	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
696406002310	FeS/SAM binding site; other site
696406002311	TRAM domain; Region: TRAM; pfam01938
696406002312	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
696406002313	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
696406002314	asparagine synthetase B; Provisional; Region: asnB; PRK09431
696406002315	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
696406002316	active site
696406002317	dimer interface [polypeptide binding]; other site
696406002318	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
696406002319	Ligand Binding Site [chemical binding]; other site
696406002320	Molecular Tunnel; other site
696406002321	UMP phosphatase; Provisional; Region: PRK10444
696406002322	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696406002323	active site
696406002324	motif I; other site
696406002325	motif II; other site
696406002326	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696406002327	MarR family; Region: MarR; pfam01047
696406002328	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
696406002329	ROK family; Region: ROK; pfam00480
696406002330	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
696406002331	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
696406002332	active site
696406002333	dimer interface [polypeptide binding]; other site
696406002334	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
696406002335	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
696406002336	active site
696406002337	trimer interface [polypeptide binding]; other site
696406002338	allosteric site; other site
696406002339	active site lid [active]
696406002340	hexamer (dimer of trimers) interface [polypeptide binding]; other site
696406002341	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
696406002342	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
696406002343	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
696406002344	active site turn [active]
696406002345	phosphorylation site [posttranslational modification]
696406002346	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
696406002347	HPr interaction site; other site
696406002348	glycerol kinase (GK) interaction site [polypeptide binding]; other site
696406002349	active site
696406002350	phosphorylation site [posttranslational modification]
696406002351	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
696406002352	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
696406002353	active site
696406002354	HIGH motif; other site
696406002355	nucleotide binding site [chemical binding]; other site
696406002356	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
696406002357	KMSKS motif; other site
696406002358	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
696406002359	outer membrane porin, OprD family; Region: OprD; pfam03573
696406002360	YbfN-like lipoprotein; Region: YbfN; pfam13982
696406002361	ferric uptake regulator; Provisional; Region: fur; PRK09462
696406002362	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
696406002363	metal binding site 2 [ion binding]; metal-binding site
696406002364	putative DNA binding helix; other site
696406002365	metal binding site 1 [ion binding]; metal-binding site
696406002366	dimer interface [polypeptide binding]; other site
696406002367	structural Zn2+ binding site [ion binding]; other site
696406002368	flavodoxin FldA; Validated; Region: PRK09267
696406002369	LexA regulated protein; Provisional; Region: PRK11675
696406002370	acyl-CoA esterase; Provisional; Region: PRK10673
696406002371	PGAP1-like protein; Region: PGAP1; pfam07819
696406002372	replication initiation regulator SeqA; Provisional; Region: PRK11187
696406002373	phosphoglucomutase, alpha-D-glucose phosphate-specific; Region: pgm; TIGR01132
696406002374	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
696406002375	active site
696406002376	substrate binding site [chemical binding]; other site
696406002377	metal binding site [ion binding]; metal-binding site
696406002378	Protein of unknown function DUF2625; Region: DUF2625; pfam10946
696406002379	putrescine transporter; Provisional; Region: potE; PRK10655
696406002380	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
696406002381	ornithine decarboxylase; Provisional; Region: PRK13578
696406002382	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
696406002383	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
696406002384	homodimer interface [polypeptide binding]; other site
696406002385	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406002386	catalytic residue [active]
696406002387	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
696406002388	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
696406002389	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406002390	active site
696406002391	phosphorylation site [posttranslational modification]
696406002392	intermolecular recognition site; other site
696406002393	dimerization interface [polypeptide binding]; other site
696406002394	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
696406002395	DNA binding site [nucleotide binding]
696406002396	sensor protein KdpD; Provisional; Region: PRK10490
696406002397	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
696406002398	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
696406002399	Ligand Binding Site [chemical binding]; other site
696406002400	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
696406002401	GAF domain; Region: GAF_3; pfam13492
696406002402	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
696406002403	dimer interface [polypeptide binding]; other site
696406002404	phosphorylation site [posttranslational modification]
696406002405	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406002406	ATP binding site [chemical binding]; other site
696406002407	Mg2+ binding site [ion binding]; other site
696406002408	G-X-G motif; other site
696406002409	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
696406002410	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
696406002411	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
696406002412	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
696406002413	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
696406002414	PAAR motif; Region: PAAR_motif; cl15808
696406002415	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
696406002416	RHS Repeat; Region: RHS_repeat; pfam05593
696406002417	RHS Repeat; Region: RHS_repeat; pfam05593
696406002418	RHS Repeat; Region: RHS_repeat; cl11982
696406002419	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
696406002420	RHS Repeat; Region: RHS_repeat; pfam05593
696406002421	RHS Repeat; Region: RHS_repeat; pfam05593
696406002422	RHS protein; Region: RHS; pfam03527
696406002423	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
696406002424	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
696406002425	RHS protein; Region: RHS; pfam03527
696406002426	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
696406002427	hypothetical protein; Provisional; Region: PRK10167
696406002428	Uncharacterized conserved protein [Function unknown]; Region: COG3272
696406002429	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
696406002430	DNA photolyase; Region: DNA_photolyase; pfam00875
696406002431	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
696406002432	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406002433	putative substrate translocation pore; other site
696406002434	POT family; Region: PTR2; pfam00854
696406002435	Uncharacterized conserved protein [Function unknown]; Region: COG0327
696406002436	metal-binding protein; Provisional; Region: PRK10799
696406002437	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
696406002438	sensor histidine kinase inhibitor, KipI family; Region: TIGR00370
696406002439	biotin-dependent carboxylase uncharacterized domain; Region: urea_amlyse_rel; TIGR00724
696406002440	Escherichia coli putative lactam utilization protein YbgL and similar proteins; Region: LamB_YcsF_YbgL_like; cd10800
696406002441	putative active site [active]
696406002442	endonuclease VIII; Provisional; Region: PRK10445
696406002443	N-terminal domain of Escherichia coli Nei/endonuclease VIII and related DNA glycosylases; Region: EcNei-like_N; cd08965
696406002444	DNA binding site [nucleotide binding]
696406002445	catalytic residue [active]
696406002446	putative catalytic residues [active]
696406002447	H2TH interface [polypeptide binding]; other site
696406002448	intercalation triad [nucleotide binding]; other site
696406002449	substrate specificity determining residue; other site
696406002450	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
696406002451	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
696406002452	Putative ammonia monooxygenase [General function prediction only]; Region: AbrB; COG3180
696406002453	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
696406002454	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
696406002455	Fimbrial protein; Region: Fimbrial; pfam00419
696406002456	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
696406002457	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
696406002458	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
696406002459	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
696406002460	PapC N-terminal domain; Region: PapC_N; pfam13954
696406002461	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
696406002462	PapC C-terminal domain; Region: PapC_C; pfam13953
696406002463	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
696406002464	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
696406002465	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
696406002466	dimer interface [polypeptide binding]; other site
696406002467	active site
696406002468	citrylCoA binding site [chemical binding]; other site
696406002469	NADH binding [chemical binding]; other site
696406002470	cationic pore residues; other site
696406002471	oxalacetate/citrate binding site [chemical binding]; other site
696406002472	coenzyme A binding site [chemical binding]; other site
696406002473	catalytic triad [active]
696406002474	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
696406002475	Iron-sulfur protein interface; other site
696406002476	proximal quinone binding site [chemical binding]; other site
696406002477	SdhD (CybS) interface [polypeptide binding]; other site
696406002478	proximal heme binding site [chemical binding]; other site
696406002479	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
696406002480	SdhC subunit interface [polypeptide binding]; other site
696406002481	proximal heme binding site [chemical binding]; other site
696406002482	cardiolipin binding site; other site
696406002483	Iron-sulfur protein interface; other site
696406002484	proximal quinone binding site [chemical binding]; other site
696406002485	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
696406002486	L-aspartate oxidase; Provisional; Region: PRK06175
696406002487	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
696406002488	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
696406002489	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
696406002490	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
696406002491	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
696406002492	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
696406002493	TPP-binding site [chemical binding]; other site
696406002494	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
696406002495	dimer interface [polypeptide binding]; other site
696406002496	PYR/PP interface [polypeptide binding]; other site
696406002497	TPP binding site [chemical binding]; other site
696406002498	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
696406002499	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
696406002500	E3 interaction surface; other site
696406002501	lipoyl attachment site [posttranslational modification]; other site
696406002502	e3 binding domain; Region: E3_binding; pfam02817
696406002503	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
696406002504	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
696406002505	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
696406002506	CoA-ligase; Region: Ligase_CoA; pfam00549
696406002507	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
696406002508	CoA binding domain; Region: CoA_binding; smart00881
696406002509	CoA-ligase; Region: Ligase_CoA; pfam00549
696406002510	DNA-binding transcriptional repressor MngR; Provisional; Region: PRK09764
696406002511	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
696406002512	DNA-binding site [nucleotide binding]; DNA binding site
696406002513	UTRA domain; Region: UTRA; pfam07702
696406002514	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
696406002515	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
696406002516	active site
696406002517	phosphorylation site [posttranslational modification]
696406002518	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
696406002519	active site
696406002520	P-loop; other site
696406002521	phosphorylation site [posttranslational modification]
696406002522	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
696406002523	alpha-mannosidase; Provisional; Region: PRK09819
696406002524	N-terminal catalytic domain of Escherichia coli alpha-mannosidase MngB and its bacterial homologs; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_EcMngB_like; cd10815
696406002525	active site
696406002526	metal binding site [ion binding]; metal-binding site
696406002527	catalytic site [active]
696406002528	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; smart00872
696406002529	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
696406002530	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
696406002531	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003
696406002532	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
696406002533	Membrane bound YbgT-like protein; Region: YbgT_YccB; cl02039
696406002534	hypothetical protein; Provisional; Region: PRK10588
696406002535	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
696406002536	active site
696406002537	colicin uptake protein TolQ; Provisional; Region: PRK10801
696406002538	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
696406002539	colicin uptake protein TolR; Provisional; Region: PRK11024
696406002540	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
696406002541	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
696406002542	TolA C-terminal; Region: TolA; pfam06519
696406002543	translocation protein TolB; Provisional; Region: tolB; PRK03629
696406002544	TolB amino-terminal domain; Region: TolB_N; pfam04052
696406002545	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
696406002546	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
696406002547	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
696406002548	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
696406002549	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
696406002550	ligand binding site [chemical binding]; other site
696406002551	tol-pal system protein YbgF; Provisional; Region: PRK10803
696406002552	Tetratricopeptide repeat; Region: TPR_6; pfam13174
696406002553	Tetratricopeptide repeat; Region: TPR_6; pfam13174
696406002554	quinolinate synthetase; Provisional; Region: PRK09375
696406002555	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
696406002556	zinc transporter ZitB; Provisional; Region: PRK03557
696406002557	YbgS-like protein; Region: YbgS; pfam13985
696406002558	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
696406002559	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
696406002560	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
696406002561	catalytic core [active]
696406002562	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
696406002563	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
696406002564	active site
696406002565	catalytic residues [active]
696406002566	galactokinase; Provisional; Region: PRK05101
696406002567	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
696406002568	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
696406002569	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
696406002570	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
696406002571	dimer interface [polypeptide binding]; other site
696406002572	active site
696406002573	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
696406002574	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
696406002575	NAD binding site [chemical binding]; other site
696406002576	homodimer interface [polypeptide binding]; other site
696406002577	active site
696406002578	substrate binding site [chemical binding]; other site
696406002579	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
696406002580	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
696406002581	Walker A/P-loop; other site
696406002582	ATP binding site [chemical binding]; other site
696406002583	Q-loop/lid; other site
696406002584	ABC transporter signature motif; other site
696406002585	Walker B; other site
696406002586	D-loop; other site
696406002587	H-loop/switch region; other site
696406002588	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
696406002589	Walker A/P-loop; other site
696406002590	ATP binding site [chemical binding]; other site
696406002591	Q-loop/lid; other site
696406002592	ABC transporter signature motif; other site
696406002593	Walker B; other site
696406002594	D-loop; other site
696406002595	H-loop/switch region; other site
696406002596	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
696406002597	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
696406002598	molybdenum-pterin binding domain; Region: Mop; TIGR00638
696406002599	TOBE domain; Region: TOBE; pfam03459
696406002600	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
696406002601	molybdate transporter periplasmic protein; Provisional; Region: modA; PRK10677
696406002602	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
696406002603	substrate binding pocket [chemical binding]; other site
696406002604	membrane-bound complex binding site; other site
696406002605	hinge residues; other site
696406002606	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
696406002607	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406002608	putative PBP binding loops; other site
696406002609	ABC-ATPase subunit interface; other site
696406002610	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
696406002611	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
696406002612	Walker A/P-loop; other site
696406002613	ATP binding site [chemical binding]; other site
696406002614	Q-loop/lid; other site
696406002615	ABC transporter signature motif; other site
696406002616	Walker B; other site
696406002617	D-loop; other site
696406002618	H-loop/switch region; other site
696406002619	molybdenum-pterin binding domain; Region: Mop; TIGR00638
696406002620	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
696406002621	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696406002622	motif II; other site
696406002623	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696406002624	6-phosphogluconolactonase; Provisional; Region: PRK11028
696406002625	Transcriptional regulator [Transcription]; Region: LysR; COG0583
696406002626	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406002627	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
696406002628	putative dimerization interface [polypeptide binding]; other site
696406002629	PrpF protein; Region: PrpF; pfam04303
696406002630	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
696406002631	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
696406002632	transmembrane helices; other site
696406002633	putative hydratase; Provisional; Region: PRK11413
696406002634	Aconitase catalytic domain; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: Aconitase; cl00285
696406002635	substrate binding site [chemical binding]; other site
696406002636	ligand binding site [chemical binding]; other site
696406002637	Aconitase swivel domain. Aconitase (aconitate hydratase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes swivelling conformational change in the enzyme...; Region: Aconitase_swivel; cl00215
696406002638	substrate binding site [chemical binding]; other site
696406002639	acyl-CoA thioesterase; Provisional; Region: PRK10531
696406002640	putative pectinesterase; Region: PLN02432; cl01911
696406002641	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
696406002642	substrate binding site [chemical binding]; other site
696406002643	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
696406002644	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
696406002645	inhibitor-cofactor binding pocket; inhibition site
696406002646	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406002647	catalytic residue [active]
696406002648	biotin synthase; Provisional; Region: PRK15108
696406002649	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
696406002650	FeS/SAM binding site; other site
696406002651	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
696406002652	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
696406002653	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
696406002654	substrate-cofactor binding pocket; other site
696406002655	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406002656	catalytic residue [active]
696406002657	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
696406002658	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406002659	S-adenosylmethionine binding site [chemical binding]; other site
696406002660	AAA domain; Region: AAA_26; pfam13500
696406002661	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
696406002662	Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the biotin biosynthesis pathway in Escherichia coli and other microorganisms. The enzyme catalyzes formation of the ureido ring of dethiobiotin from (7R,8S)-7,8-diaminononanoic acid (DAPA) and...; Region: DTBS; cd03109
696406002663	ADP binding site [chemical binding]; other site
696406002664	excinuclease ABC subunit B; Provisional; Region: PRK05298
696406002665	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
696406002666	ATP binding site [chemical binding]; other site
696406002667	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
696406002668	nucleotide binding region [chemical binding]; other site
696406002669	ATP-binding site [chemical binding]; other site
696406002670	Ultra-violet resistance protein B; Region: UvrB; pfam12344
696406002671	UvrB/uvrC motif; Region: UVR; pfam02151
696406002672	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
696406002673	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
696406002674	putative substrate binding pocket [chemical binding]; other site
696406002675	dimer interface [polypeptide binding]; other site
696406002676	phosphate binding site [ion binding]; other site
696406002677	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
696406002678	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
696406002679	FeS/SAM binding site; other site
696406002680	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
696406002681	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
696406002682	MPT binding site; other site
696406002683	trimer interface [polypeptide binding]; other site
696406002684	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
696406002685	trimer interface [polypeptide binding]; other site
696406002686	dimer interface [polypeptide binding]; other site
696406002687	putative active site [active]
696406002688	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
696406002689	MoaE interaction surface [polypeptide binding]; other site
696406002690	MoeB interaction surface [polypeptide binding]; other site
696406002691	thiocarboxylated glycine; other site
696406002692	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
696406002693	MoaE homodimer interface [polypeptide binding]; other site
696406002694	MoaD interaction [polypeptide binding]; other site
696406002695	active site residues [active]
696406002696	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
696406002697	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
696406002698	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
696406002699	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
696406002700	Predicted integral membrane protein [Function unknown]; Region: COG0392
696406002701	cardiolipin synthase 2; Provisional; Region: PRK11263
696406002702	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
696406002703	putative active site [active]
696406002704	catalytic site [active]
696406002705	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
696406002706	putative active site [active]
696406002707	catalytic site [active]
696406002708	Metal-dependent hydrolase [General function prediction only]; Region: ElsH; COG3568
696406002709	putative catalytic site [active]
696406002710	putative metal binding site [ion binding]; other site
696406002711	putative phosphate binding site [ion binding]; other site
696406002712	Putative inner membrane protein YbhQ; Region: YbhQ; pfam11076
696406002713	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
696406002714	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
696406002715	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
696406002716	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
696406002717	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
696406002718	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
696406002719	Walker A/P-loop; other site
696406002720	ATP binding site [chemical binding]; other site
696406002721	Q-loop/lid; other site
696406002722	ABC transporter signature motif; other site
696406002723	Walker B; other site
696406002724	D-loop; other site
696406002725	H-loop/switch region; other site
696406002726	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
696406002727	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
696406002728	Walker A/P-loop; other site
696406002729	ATP binding site [chemical binding]; other site
696406002730	Q-loop/lid; other site
696406002731	ABC transporter signature motif; other site
696406002732	Walker B; other site
696406002733	D-loop; other site
696406002734	H-loop/switch region; other site
696406002735	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
696406002736	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
696406002737	HlyD family secretion protein; Region: HlyD_3; pfam13437
696406002738	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
696406002739	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
696406002740	helicase 45; Provisional; Region: PTZ00424
696406002741	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
696406002742	ATP binding site [chemical binding]; other site
696406002743	Mg++ binding site [ion binding]; other site
696406002744	motif III; other site
696406002745	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
696406002746	nucleotide binding region [chemical binding]; other site
696406002747	ATP-binding site [chemical binding]; other site
696406002748	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3236
696406002749	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
696406002750	DEAD_2; Region: DEAD_2; pfam06733
696406002751	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
696406002752	glycosyl transferase family protein; Provisional; Region: PRK08136
696406002753	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
696406002754	putative dehydrogenase; Provisional; Region: PRK10098
696406002755	hypothetical protein; Provisional; Region: PRK10259
696406002756	hypothetical protein; Provisional; Region: PRK11019
696406002757	Fe(II)-dependent oxygenase superfamily protein; Provisional; Region: PRK05467
696406002758	catecholate siderophore receptor Fiu; Provisional; Region: PRK09840
696406002759	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
696406002760	N-terminal plug; other site
696406002761	ligand-binding site [chemical binding]; other site
696406002762	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
696406002763	23S rRNA mA1618 methyltransferase; Provisional; Region: PRK11727
696406002764	Protein of unknown function (DUF890); Region: Methyltransf_10; pfam05971
696406002765	putative mechanosensitive channel protein; Provisional; Region: PRK11465
696406002766	Mechanosensitive ion channel; Region: MS_channel; pfam00924
696406002767	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
696406002768	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
696406002769	Walker A/P-loop; other site
696406002770	ATP binding site [chemical binding]; other site
696406002771	Q-loop/lid; other site
696406002772	ABC transporter signature motif; other site
696406002773	Walker B; other site
696406002774	D-loop; other site
696406002775	H-loop/switch region; other site
696406002776	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
696406002777	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406002778	dimer interface [polypeptide binding]; other site
696406002779	conserved gate region; other site
696406002780	putative PBP binding loops; other site
696406002781	ABC-ATPase subunit interface; other site
696406002782	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
696406002783	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
696406002784	substrate binding pocket [chemical binding]; other site
696406002785	membrane-bound complex binding site; other site
696406002786	hinge residues; other site
696406002787	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
696406002788	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
696406002789	dimerization interface [polypeptide binding]; other site
696406002790	DPS ferroxidase diiron center [ion binding]; other site
696406002791	ion pore; other site
696406002792	threonine and homoserine efflux system; Provisional; Region: PRK10532
696406002793	EamA-like transporter family; Region: EamA; pfam00892
696406002794	outer membrane protein X; Provisional; Region: ompX; PRK09408
696406002795	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
696406002796	Sulfatase; Region: Sulfatase; pfam00884
696406002797	manganese transport regulator MntR; Provisional; Region: PRK11050
696406002798	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
696406002799	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
696406002800	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
696406002801	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
696406002802	transmembrane helices; other site
696406002803	L,D-transpeptidase; Provisional; Region: PRK10260
696406002804	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
696406002805	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
696406002806	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
696406002807	Walker A/P-loop; other site
696406002808	ATP binding site [chemical binding]; other site
696406002809	Q-loop/lid; other site
696406002810	ABC transporter signature motif; other site
696406002811	Walker B; other site
696406002812	D-loop; other site
696406002813	H-loop/switch region; other site
696406002814	ABC transporter; Region: ABC_tran_2; pfam12848
696406002815	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
696406002816	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
696406002817	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
696406002818	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696406002819	active site
696406002820	motif I; other site
696406002821	motif II; other site
696406002822	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696406002823	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
696406002824	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
696406002825	dimer interface [polypeptide binding]; other site
696406002826	active site
696406002827	glycine loop; other site
696406002828	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
696406002829	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
696406002830	active site
696406002831	intersubunit interactions; other site
696406002832	catalytic residue [active]
696406002833	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
696406002834	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
696406002835	ATP binding site [chemical binding]; other site
696406002836	substrate interface [chemical binding]; other site
696406002837	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
696406002838	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
696406002839	dimer interface [polypeptide binding]; other site
696406002840	putative functional site; other site
696406002841	putative MPT binding site; other site
696406002842	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
696406002843	catalytic nucleophile [active]
696406002844	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
696406002845	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
696406002846	Walker A/P-loop; other site
696406002847	ATP binding site [chemical binding]; other site
696406002848	Q-loop/lid; other site
696406002849	ABC transporter signature motif; other site
696406002850	Walker B; other site
696406002851	D-loop; other site
696406002852	H-loop/switch region; other site
696406002853	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
696406002854	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
696406002855	Walker A/P-loop; other site
696406002856	ATP binding site [chemical binding]; other site
696406002857	Q-loop/lid; other site
696406002858	ABC transporter signature motif; other site
696406002859	Walker B; other site
696406002860	D-loop; other site
696406002861	H-loop/switch region; other site
696406002862	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
696406002863	glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413
696406002864	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
696406002865	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
696406002866	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406002867	dimer interface [polypeptide binding]; other site
696406002868	conserved gate region; other site
696406002869	putative PBP binding loops; other site
696406002870	ABC-ATPase subunit interface; other site
696406002871	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
696406002872	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
696406002873	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406002874	dimer interface [polypeptide binding]; other site
696406002875	conserved gate region; other site
696406002876	putative PBP binding loops; other site
696406002877	ABC-ATPase subunit interface; other site
696406002878	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
696406002879	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
696406002880	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
696406002881	metal binding site [ion binding]; metal-binding site
696406002882	active site
696406002883	I-site; other site
696406002884	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
696406002885	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
696406002886	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
696406002887	FeS/SAM binding site; other site
696406002888	biofilm formation regulatory protein BssR; Reviewed; Region: bssR; PRK12302
696406002889	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
696406002890	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
696406002891	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
696406002892	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
696406002893	putative C-terminal domain interface [polypeptide binding]; other site
696406002894	putative GSH binding site (G-site) [chemical binding]; other site
696406002895	putative dimer interface [polypeptide binding]; other site
696406002896	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
696406002897	N-terminal domain interface [polypeptide binding]; other site
696406002898	dimer interface [polypeptide binding]; other site
696406002899	substrate binding pocket (H-site) [chemical binding]; other site
696406002900	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
696406002901	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
696406002902	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
696406002903	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
696406002904	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
696406002905	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
696406002906	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
696406002907	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
696406002908	active site
696406002909	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
696406002910	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406002911	putative substrate translocation pore; other site
696406002912	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
696406002913	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696406002914	active site
696406002915	motif I; other site
696406002916	motif II; other site
696406002917	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696406002918	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
696406002919	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406002920	putative substrate translocation pore; other site
696406002921	Major Facilitator Superfamily; Region: MFS_1; pfam07690
696406002922	transcriptional repressor BetI; Region: betaine_BetI; TIGR03384
696406002923	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
696406002924	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
696406002925	integrase; Provisional; Region: int; PHA02601
696406002926	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
696406002927	active site
696406002928	DNA binding site [nucleotide binding]
696406002929	Int/Topo IB signature motif; other site
696406002930	Phage regulatory protein CII (CP76); Region: Phage_CP76; pfam06892
696406002931	Protein of unknown function (DUF2724); Region: DUF2724; pfam10893
696406002932	Protein of unknown function (DUF2732); Region: DUF2732; pfam10809
696406002933	DksA-like zinc finger domain containing protein; Region: PHA00080
696406002934	DNA adenine methylase (dam); Region: dam; TIGR00571
696406002935	Herpesvirus large structural phosphoprotein UL32; Region: Herpes_UL32; pfam06070
696406002936	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
696406002937	DinI-like family; Region: DinI; pfam06183
696406002938	Phage-related protein [Function unknown]; Region: COG5412
696406002939	Protein of unknown function DUF262; Region: DUF262; pfam03235
696406002940	Uncharacterized conserved protein [Function unknown]; Region: COG1479
696406002941	portal vertex protein; Provisional; Region: Q; PHA02536
696406002942	Phage portal protein; Region: Phage_portal; pfam04860
696406002943	terminase ATPase subunit; Provisional; Region: P; PHA02535
696406002944	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
696406002945	Mu-like prophage FluMu protein gp28 [General function prediction only]; Region: COG4373
696406002946	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; pfam05929
696406002947	capsid protein; Provisional; Region: N; PHA02538
696406002948	terminase endonuclease subunit; Provisional; Region: M; PHA02537
696406002949	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
696406002950	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
696406002951	P2-like prophage tail protein X [General function prediction only]; Region: COG5004
696406002952	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
696406002953	catalytic residues [active]
696406002954	phage lysis regulatory protein, LysB family; Region: phage_LysB; TIGR03495
696406002955	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
696406002956	Phage virion morphogenesis family; Region: Phage_tail_S; pfam05069
696406002957	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
696406002958	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
696406002959	baseplate wedge subunit; Provisional; Region: W; PHA02516
696406002960	baseplate assembly protein; Provisional; Region: J; PHA02568
696406002961	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
696406002962	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
696406002963	Phage Tail Collar Domain; Region: Collar; pfam07484
696406002964	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
696406002965	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
696406002966	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
696406002967	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
696406002968	catalytic residues [active]
696406002969	catalytic nucleophile [active]
696406002970	Presynaptic Site I dimer interface [polypeptide binding]; other site
696406002971	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
696406002972	Synaptic Flat tetramer interface [polypeptide binding]; other site
696406002973	Synaptic Site I dimer interface [polypeptide binding]; other site
696406002974	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
696406002975	DNA-binding interface [nucleotide binding]; DNA binding site
696406002976	major tail sheath protein; Provisional; Region: FI; PHA02560
696406002977	major tail tube protein; Provisional; Region: FII; PHA02600
696406002978	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
696406002979	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
696406002980	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
696406002981	Phage protein U [General function prediction only]; Region: COG3499
696406002982	tail protein; Provisional; Region: D; PHA02561
696406002983	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
696406002984	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
696406002985	putative transporter; Provisional; Region: PRK04972
696406002986	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
696406002987	TrkA-C domain; Region: TrkA_C; pfam02080
696406002988	TrkA-C domain; Region: TrkA_C; pfam02080
696406002989	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
696406002990	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
696406002991	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
696406002992	GSH binding site [chemical binding]; other site
696406002993	catalytic residues [active]
696406002994	Protein of unknown function (DUF1418); Region: DUF1418; pfam07214
696406002995	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
696406002996	dimer interface [polypeptide binding]; other site
696406002997	FMN binding site [chemical binding]; other site
696406002998	NADPH bind site [chemical binding]; other site
696406002999	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
696406003000	DNA-binding interface [nucleotide binding]; DNA binding site
696406003001	Helix-turn-helix domain; Region: HTH_38; pfam13936
696406003002	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
696406003003	RimK-like ATP-grasp domain; Region: RimK; pfam08443
696406003004	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
696406003005	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
696406003006	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
696406003007	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
696406003008	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
696406003009	Walker A/P-loop; other site
696406003010	ATP binding site [chemical binding]; other site
696406003011	Q-loop/lid; other site
696406003012	ABC transporter signature motif; other site
696406003013	Walker B; other site
696406003014	D-loop; other site
696406003015	H-loop/switch region; other site
696406003016	TOBE domain; Region: TOBE_2; pfam08402
696406003017	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
696406003018	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406003019	dimer interface [polypeptide binding]; other site
696406003020	conserved gate region; other site
696406003021	putative PBP binding loops; other site
696406003022	ABC-ATPase subunit interface; other site
696406003023	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
696406003024	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406003025	dimer interface [polypeptide binding]; other site
696406003026	conserved gate region; other site
696406003027	putative PBP binding loops; other site
696406003028	ABC-ATPase subunit interface; other site
696406003029	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
696406003030	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
696406003031	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406003032	S-adenosylmethionine binding site [chemical binding]; other site
696406003033	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
696406003034	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
696406003035	substrate binding pocket [chemical binding]; other site
696406003036	membrane-bound complex binding site; other site
696406003037	hinge residues; other site
696406003038	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406003039	dimer interface [polypeptide binding]; other site
696406003040	conserved gate region; other site
696406003041	putative PBP binding loops; other site
696406003042	ABC-ATPase subunit interface; other site
696406003043	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
696406003044	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406003045	dimer interface [polypeptide binding]; other site
696406003046	conserved gate region; other site
696406003047	putative PBP binding loops; other site
696406003048	ABC-ATPase subunit interface; other site
696406003049	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
696406003050	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
696406003051	substrate binding pocket [chemical binding]; other site
696406003052	membrane-bound complex binding site; other site
696406003053	hinge residues; other site
696406003054	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
696406003055	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
696406003056	Walker A/P-loop; other site
696406003057	ATP binding site [chemical binding]; other site
696406003058	Q-loop/lid; other site
696406003059	ABC transporter signature motif; other site
696406003060	Walker B; other site
696406003061	D-loop; other site
696406003062	H-loop/switch region; other site
696406003063	putative lipoprotein; Provisional; Region: PRK10533
696406003064	hypothetical protein; Provisional; Region: PRK02877
696406003065	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
696406003066	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
696406003067	amidase catalytic site [active]
696406003068	Zn binding residues [ion binding]; other site
696406003069	substrate binding site [chemical binding]; other site
696406003070	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
696406003071	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
696406003072	NAD(P) binding site [chemical binding]; other site
696406003073	active site
696406003074	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
696406003075	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
696406003076	putative NAD(P) binding site [chemical binding]; other site
696406003077	putative active site [active]
696406003078	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
696406003079	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
696406003080	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
696406003081	tetramer interface [polypeptide binding]; other site
696406003082	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406003083	catalytic residue [active]
696406003084	pyruvate dehydrogenase; Provisional; Region: PRK09124
696406003085	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
696406003086	PYR/PP interface [polypeptide binding]; other site
696406003087	dimer interface [polypeptide binding]; other site
696406003088	tetramer interface [polypeptide binding]; other site
696406003089	TPP binding site [chemical binding]; other site
696406003090	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
696406003091	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
696406003092	TPP-binding site [chemical binding]; other site
696406003093	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
696406003094	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
696406003095	FAD binding pocket [chemical binding]; other site
696406003096	FAD binding motif [chemical binding]; other site
696406003097	phosphate binding motif [ion binding]; other site
696406003098	beta-alpha-beta structure motif; other site
696406003099	NAD binding pocket [chemical binding]; other site
696406003100	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
696406003101	catalytic loop [active]
696406003102	iron binding site [ion binding]; other site
696406003103	hybrid cluster protein; Provisional; Region: PRK05290
696406003104	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
696406003105	ACS interaction site; other site
696406003106	CODH interaction site; other site
696406003107	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
696406003108	hybrid metal cluster; other site
696406003109	Predicted membrane protein [Function unknown]; Region: COG2431
696406003110	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
696406003111	amphipathic channel; other site
696406003112	Asn-Pro-Ala signature motifs; other site
696406003113	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
696406003114	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
696406003115	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
696406003116	putative active site [active]
696406003117	putative metal-binding site [ion binding]; other site
696406003118	Protein of unknown function (DUF535); Region: DUF535; pfam04393
696406003119	macrolide transporter subunit MacA; Provisional; Region: PRK11578
696406003120	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
696406003121	HlyD family secretion protein; Region: HlyD_3; pfam13437
696406003122	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
696406003123	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
696406003124	Walker A/P-loop; other site
696406003125	ATP binding site [chemical binding]; other site
696406003126	Q-loop/lid; other site
696406003127	ABC transporter signature motif; other site
696406003128	Walker B; other site
696406003129	D-loop; other site
696406003130	H-loop/switch region; other site
696406003131	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
696406003132	FtsX-like permease family; Region: FtsX; pfam02687
696406003133	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
696406003134	DNA-binding site [nucleotide binding]; DNA binding site
696406003135	RNA-binding motif; other site
696406003136	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
696406003137	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
696406003138	Clp amino terminal domain; Region: Clp_N; pfam02861
696406003139	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406003140	Walker A motif; other site
696406003141	ATP binding site [chemical binding]; other site
696406003142	Walker B motif; other site
696406003143	arginine finger; other site
696406003144	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406003145	Walker A motif; other site
696406003146	ATP binding site [chemical binding]; other site
696406003147	Walker B motif; other site
696406003148	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
696406003149	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
696406003150	rRNA binding site [nucleotide binding]; other site
696406003151	predicted 30S ribosome binding site; other site
696406003152	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
696406003153	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
696406003154	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
696406003155	ATP-binding cassette domain of CydCD, subfamily C; Region: ABCC_cytochrome_bd; cd03247
696406003156	Walker A/P-loop; other site
696406003157	ATP binding site [chemical binding]; other site
696406003158	Q-loop/lid; other site
696406003159	ABC transporter signature motif; other site
696406003160	Walker B; other site
696406003161	D-loop; other site
696406003162	H-loop/switch region; other site
696406003163	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
696406003164	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
696406003165	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
696406003166	Walker A/P-loop; other site
696406003167	ATP binding site [chemical binding]; other site
696406003168	Q-loop/lid; other site
696406003169	ABC transporter signature motif; other site
696406003170	Walker B; other site
696406003171	D-loop; other site
696406003172	H-loop/switch region; other site
696406003173	thioredoxin reductase; Provisional; Region: PRK10262
696406003174	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
696406003175	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
696406003176	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
696406003177	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
696406003178	putative DNA binding site [nucleotide binding]; other site
696406003179	putative Zn2+ binding site [ion binding]; other site
696406003180	AsnC family; Region: AsnC_trans_reg; pfam01037
696406003181	DNA translocase FtsK; Provisional; Region: PRK10263
696406003182	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
696406003183	DNA translocase FtsK; Provisional; Region: PRK10263
696406003184	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
696406003185	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
696406003186	periplasmic chaperone LolA; Region: lolA; TIGR00547
696406003187	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
696406003188	recombination factor protein RarA; Reviewed; Region: PRK13342
696406003189	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406003190	Walker A motif; other site
696406003191	ATP binding site [chemical binding]; other site
696406003192	Walker B motif; other site
696406003193	arginine finger; other site
696406003194	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
696406003195	seryl-tRNA synthetase; Provisional; Region: PRK05431
696406003196	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
696406003197	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
696406003198	dimer interface [polypeptide binding]; other site
696406003199	active site
696406003200	motif 1; other site
696406003201	motif 2; other site
696406003202	motif 3; other site
696406003203	Toxin YafO, type II toxin-antitoxin system; Region: YafO_toxin; pfam13957
696406003204	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
696406003205	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
696406003206	tail protein; Provisional; Region: D; PHA02561
696406003207	Phage tail sheath protein FI [General function prediction only]; Region: COG3497
696406003208	Phage tail tube protein FII; Region: Phage_tube; cl01390
696406003209	Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109
696406003210	Phage P2 GpE; Region: Phage_P2_GpE; pfam06528
696406003211	phage tail tape measure protein, TP901 family, core region; Region: tape_meas_TP901; TIGR01760
696406003212	Phage protein U [General function prediction only]; Region: COG3499
696406003213	multiple promoter invertase; Provisional; Region: mpi; PRK13413
696406003214	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
696406003215	catalytic residues [active]
696406003216	catalytic nucleophile [active]
696406003217	Presynaptic Site I dimer interface [polypeptide binding]; other site
696406003218	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
696406003219	Synaptic Flat tetramer interface [polypeptide binding]; other site
696406003220	Synaptic Site I dimer interface [polypeptide binding]; other site
696406003221	DNA binding site [nucleotide binding]
696406003222	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
696406003223	DNA-binding interface [nucleotide binding]; DNA binding site
696406003224	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
696406003225	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
696406003226	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
696406003227	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
696406003228	Baseplate J-like protein; Region: Baseplate_J; cl01294
696406003229	Gene 25-like lysozyme; Region: GPW_gp25; cl01403
696406003230	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
696406003231	Phage virion morphogenesis family; Region: Phage_tail_S; cl02089
696406003232	putative transposase OrfB; Reviewed; Region: PHA02517
696406003233	HTH-like domain; Region: HTH_21; pfam13276
696406003234	Integrase core domain; Region: rve; pfam00665
696406003235	Integrase core domain; Region: rve_3; pfam13683
696406003236	Phage virion morphogenesis family; Region: Phage_tail_S; cl02089
696406003237	Phage virion morphogenesis family; Region: Phage_tail_S; cl02089
696406003238	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
696406003239	Protein of unknown function (DUF2570); Region: DUF2570; pfam10828
696406003240	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539
696406003241	Phage holin family (Lysis protein S); Region: Phage_holin_3; cl04938
696406003242	Phage Tail Protein X; Region: Phage_tail_X; pfam05489
696406003243	Phage head completion protein (GPL); Region: Phage_GPL; pfam05926
696406003244	terminase endonuclease subunit; Provisional; Region: M; PHA02537
696406003245	Phage small terminase subunit; Region: Phage_term_smal; pfam05944
696406003246	Phage major capsid protein, P2 family; Region: Phage_cap_P2; cl04947
696406003247	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; cl15838
696406003248	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
696406003249	terminase ATPase subunit; Provisional; Region: P; PHA02535
696406003250	Phage-related protein [Function unknown]; Region: COG4695; cl01923
696406003251	Phage portal protein; Region: Phage_portal; pfam04860
696406003252	Subtilisin-like serine proteases [Posttranslational modification, protein turnover, chaperones]; Region: AprE; COG1404
696406003253	Peptidase S8 family domain in Subtilisin-like proteins; Region: Peptidases_S8_Subtilisin_like_2; cd04847
696406003254	active site
696406003255	catalytic triad [active]
696406003256	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406003257	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
696406003258	Walker A motif; other site
696406003259	ATP binding site [chemical binding]; other site
696406003260	Walker B motif; other site
696406003261	arginine finger; other site
696406003262	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840
696406003263	Transcriptional regulators [Transcription]; Region: MarR; COG1846
696406003264	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
696406003265	putative DNA binding site [nucleotide binding]; other site
696406003266	putative Zn2+ binding site [ion binding]; other site
696406003267	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
696406003268	non-specific DNA binding site [nucleotide binding]; other site
696406003269	salt bridge; other site
696406003270	sequence-specific DNA binding site [nucleotide binding]; other site
696406003271	integrase; Provisional; Region: int; PHA02601
696406003272	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
696406003273	active site
696406003274	DNA binding site [nucleotide binding]
696406003275	Int/Topo IB signature motif; other site
696406003276	anaerobic dimethyl sulfoxide reductase subunit A; Provisional; Region: PRK14990
696406003277	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
696406003278	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
696406003279	putative [Fe4-S4] binding site [ion binding]; other site
696406003280	putative molybdopterin cofactor binding site [chemical binding]; other site
696406003281	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
696406003282	putative molybdopterin cofactor binding site; other site
696406003283	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
696406003284	4Fe-4S binding domain; Region: Fer4; pfam00037
696406003285	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
696406003286	Isochorismatase family; Region: Isochorismatase; pfam00857
696406003287	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
696406003288	catalytic triad [active]
696406003289	dimer interface [polypeptide binding]; other site
696406003290	conserved cis-peptide bond; other site
696406003291	putative MFS family transporter protein; Provisional; Region: PRK03633
696406003292	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406003293	putative substrate translocation pore; other site
696406003294	Amino acid permease; Region: AA_permease_2; pfam13520
696406003295	Transcriptional regulator [Transcription]; Region: LysR; COG0583
696406003296	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406003297	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
696406003298	putative effector binding pocket; other site
696406003299	putative dimerization interface [polypeptide binding]; other site
696406003300	hypothetical protein; Provisional; Region: PRK09739
696406003301	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
696406003302	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
696406003303	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
696406003304	FeS/SAM binding site; other site
696406003305	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
696406003306	Pyruvate formate lyase 1; Region: PFL1; cd01678
696406003307	coenzyme A binding site [chemical binding]; other site
696406003308	active site
696406003309	catalytic residues [active]
696406003310	glycine loop; other site
696406003311	Formate/nitrite transporter; Region: Form_Nir_trans; cl00927
696406003312	uncharacterized domain; Region: TIGR00702
696406003313	YcaO-like family; Region: YcaO; pfam02624
696406003314	Predicted membrane protein [Function unknown]; Region: COG2323
696406003315	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
696406003316	homodimer interface [polypeptide binding]; other site
696406003317	substrate-cofactor binding pocket; other site
696406003318	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406003319	catalytic residue [active]
696406003320	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
696406003321	Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine enolpyruvyl transferase. Both enzymes catalyze the reaction of enolpyruvyl transfer; Region: EPT-like; cd01554
696406003322	hinge; other site
696406003323	active site
696406003324	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
696406003325	cytidylate kinase; Provisional; Region: cmk; PRK00023
696406003326	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
696406003327	CMP-binding site; other site
696406003328	The sites determining sugar specificity; other site
696406003329	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
696406003330	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
696406003331	RNA binding site [nucleotide binding]; other site
696406003332	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
696406003333	RNA binding site [nucleotide binding]; other site
696406003334	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
696406003335	RNA binding site [nucleotide binding]; other site
696406003336	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
696406003337	RNA binding site [nucleotide binding]; other site
696406003338	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
696406003339	RNA binding site [nucleotide binding]; other site
696406003340	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
696406003341	IHF dimer interface [polypeptide binding]; other site
696406003342	IHF - DNA interface [nucleotide binding]; other site
696406003343	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
696406003344	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
696406003345	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
696406003346	Walker A/P-loop; other site
696406003347	ATP binding site [chemical binding]; other site
696406003348	Q-loop/lid; other site
696406003349	ABC transporter signature motif; other site
696406003350	Walker B; other site
696406003351	D-loop; other site
696406003352	H-loop/switch region; other site
696406003353	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
696406003354	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
696406003355	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3214
696406003356	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
696406003357	hypothetical protein; Provisional; Region: PRK11827
696406003358	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
696406003359	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
696406003360	Ligand binding site; other site
696406003361	oligomer interface; other site
696406003362	hypothetical protein; Provisional; Region: PRK10593
696406003363	Uncharacterized conserved protein [Function unknown]; Region: COG1434
696406003364	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
696406003365	putative active site [active]
696406003366	Methyltransferase domain; Region: Methyltransf_31; pfam13847
696406003367	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406003368	S-adenosylmethionine binding site [chemical binding]; other site
696406003369	condesin subunit F; Provisional; Region: PRK05260
696406003370	condesin subunit E; Provisional; Region: PRK05256
696406003371	Uncharacterized protein involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: MukB; COG3096
696406003372	MukB N-terminal; Region: MukB; pfam04310
696406003373	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
696406003374	murein L,D-transpeptidase; Provisional; Region: PRK10594
696406003375	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
696406003376	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
696406003377	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
696406003378	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
696406003379	Peptidase M15; Region: Peptidase_M15_3; cl01194
696406003380	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
696406003381	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
696406003382	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
696406003383	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406003384	homodimer interface [polypeptide binding]; other site
696406003385	catalytic residue [active]
696406003386	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
696406003387	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
696406003388	trimer interface [polypeptide binding]; other site
696406003389	eyelet of channel; other site
696406003390	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
696406003391	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
696406003392	putative dimer interface [polypeptide binding]; other site
696406003393	putative anticodon binding site; other site
696406003394	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
696406003395	homodimer interface [polypeptide binding]; other site
696406003396	motif 1; other site
696406003397	motif 2; other site
696406003398	active site
696406003399	motif 3; other site
696406003400	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
696406003401	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
696406003402	active site
696406003403	aminopeptidase N; Provisional; Region: pepN; PRK14015
696406003404	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
696406003405	active site
696406003406	Zn binding site [ion binding]; other site
696406003407	aliphatic sulfonates transport ATP-binding subunit; Provisional; Region: ssuB; PRK11247
696406003408	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
696406003409	Walker A/P-loop; other site
696406003410	ATP binding site [chemical binding]; other site
696406003411	Q-loop/lid; other site
696406003412	ABC transporter signature motif; other site
696406003413	Walker B; other site
696406003414	D-loop; other site
696406003415	H-loop/switch region; other site
696406003416	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
696406003417	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406003418	dimer interface [polypeptide binding]; other site
696406003419	conserved gate region; other site
696406003420	putative PBP binding loops; other site
696406003421	ABC-ATPase subunit interface; other site
696406003422	alkanesulfonate monooxygenase; Provisional; Region: PRK00719
696406003423	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
696406003424	active site
696406003425	dimer interface [polypeptide binding]; other site
696406003426	non-prolyl cis peptide bond; other site
696406003427	insertion regions; other site
696406003428	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
696406003429	substrate binding pocket [chemical binding]; other site
696406003430	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
696406003431	membrane-bound complex binding site; other site
696406003432	hinge residues; other site
696406003433	NAD(P)H-dependent FMN reductase; Provisional; Region: PRK10569
696406003434	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
696406003435	Fimbrial protein; Region: Fimbrial; cl01416
696406003436	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
696406003437	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
696406003438	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
696406003439	outer membrane usher protein; Provisional; Region: PRK15193
696406003440	PapC N-terminal domain; Region: PapC_N; pfam13954
696406003441	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
696406003442	PapC C-terminal domain; Region: PapC_C; pfam13953
696406003443	Fimbrial protein; Region: Fimbrial; cl01416
696406003444	Fimbrial protein; Region: Fimbrial; cl01416
696406003445	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
696406003446	putativi pili assembly chaperone; Provisional; Region: PRK11385
696406003447	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
696406003448	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
696406003449	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
696406003450	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
696406003451	quinone interaction residues [chemical binding]; other site
696406003452	active site
696406003453	catalytic residues [active]
696406003454	FMN binding site [chemical binding]; other site
696406003455	substrate binding site [chemical binding]; other site
696406003456	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
696406003457	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
696406003458	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
696406003459	MOSC domain; Region: MOSC; pfam03473
696406003460	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
696406003461	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
696406003462	catalytic loop [active]
696406003463	iron binding site [ion binding]; other site
696406003464	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
696406003465	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
696406003466	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
696406003467	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406003468	S-adenosylmethionine binding site [chemical binding]; other site
696406003469	ABC transporter ATPase component; Reviewed; Region: PRK11147
696406003470	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
696406003471	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
696406003472	Walker A/P-loop; other site
696406003473	Walker A/P-loop; other site
696406003474	ATP binding site [chemical binding]; other site
696406003475	ATP binding site [chemical binding]; other site
696406003476	Q-loop/lid; other site
696406003477	Q-loop/lid; other site
696406003478	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
696406003479	ABC transporter signature motif; other site
696406003480	Walker B; other site
696406003481	D-loop; other site
696406003482	ABC transporter; Region: ABC_tran_2; pfam12848
696406003483	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
696406003484	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
696406003485	Paraquat-inducible protein A; Region: PqiA; pfam04403
696406003486	Paraquat-inducible protein A; Region: PqiA; pfam04403
696406003487	paraquat-inducible protein B; Provisional; Region: PRK10807
696406003488	mce related protein; Region: MCE; pfam02470
696406003489	mce related protein; Region: MCE; pfam02470
696406003490	mce related protein; Region: MCE; pfam02470
696406003491	DASH complex subunit Duo1; Region: DASH_Duo1; pfam08651
696406003492	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
696406003493	Protein of unknown function (DUF330); Region: DUF330; pfam03886
696406003494	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
696406003495	active site 1 [active]
696406003496	dimer interface [polypeptide binding]; other site
696406003497	active site 2 [active]
696406003498	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
696406003499	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
696406003500	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
696406003501	outer membrane protein A; Reviewed; Region: PRK10808
696406003502	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
696406003503	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
696406003504	ligand binding site [chemical binding]; other site
696406003505	cell division inhibitor SulA; Region: sula; TIGR00623
696406003506	Regulator of competence-specific genes [Transcription]; Region: TfoX; COG3070
696406003507	TfoX C-terminal domain; Region: TfoX_C; pfam04994
696406003508	TIGR01666 family membrane protein; Region: YCCS
696406003509	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
696406003510	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
696406003511	Predicted membrane protein [Function unknown]; Region: COG3304
696406003512	Domain of unknown function (DUF307); Region: DUF307; pfam03733
696406003513	Domain of unknown function (DUF307); Region: DUF307; pfam03733
696406003514	DNA helicase IV; Provisional; Region: helD; PRK11054
696406003515	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
696406003516	Part of AAA domain; Region: AAA_19; pfam13245
696406003517	Family description; Region: UvrD_C_2; pfam13538
696406003518	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
696406003519	active site
696406003520	dimer interfaces [polypeptide binding]; other site
696406003521	catalytic residues [active]
696406003522	hypothetical protein; Provisional; Region: PRK03641
696406003523	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3110
696406003524	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
696406003525	heat shock protein HspQ; Provisional; Region: PRK14129
696406003526	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
696406003527	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
696406003528	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
696406003529	putative RNA binding site [nucleotide binding]; other site
696406003530	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406003531	S-adenosylmethionine binding site [chemical binding]; other site
696406003532	Acylphosphatase; Region: Acylphosphatase; cl00551
696406003533	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
696406003534	sulfur transfer protein TusE; Provisional; Region: PRK11508
696406003535	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
696406003536	YccA-like proteins; Region: YccA_like; cd10433
696406003537	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
696406003538	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
696406003539	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
696406003540	hydrogenase 1 large subunit; Provisional; Region: PRK10170
696406003541	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
696406003542	hydrogenase 1 b-type cytochrome subunit; Provisional; Region: PRK10171
696406003543	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
696406003544	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
696406003545	putative substrate-binding site; other site
696406003546	nickel binding site [ion binding]; other site
696406003547	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
696406003548	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
696406003549	cytochrome bd-II oxidase subunit 1; Provisional; Region: PRK15035
696406003550	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
696406003551	cytochrome bd-II oxidase subunit 2; Provisional; Region: PRK15028
696406003552	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
696406003553	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
696406003554	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
696406003555	catalytic core [active]
696406003556	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
696406003557	cryptic autophosphorylating protein tyrosine kinase Etk; Provisional; Region: PRK09841
696406003558	Chain length determinant protein; Region: Wzz; pfam02706
696406003559	Chain length determinant protein; Region: Wzz; cl15801
696406003560	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
696406003561	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
696406003562	P loop; other site
696406003563	Nucleotide binding site [chemical binding]; other site
696406003564	Low molecular weight phosphatase family; Region: LMWPc; cd00115
696406003565	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
696406003566	active site
696406003567	polysaccharide export protein Wza; Provisional; Region: PRK15078
696406003568	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
696406003569	SLBB domain; Region: SLBB; pfam10531
696406003570	SLBB domain; Region: SLBB; pfam10531
696406003571	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
696406003572	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
696406003573	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
696406003574	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
696406003575	DNA-binding site [nucleotide binding]; DNA binding site
696406003576	RNA-binding motif; other site
696406003577	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
696406003578	DNA-binding site [nucleotide binding]; DNA binding site
696406003579	RNA-binding motif; other site
696406003580	GnsA/GnsB family; Region: GnsAB; pfam08178
696406003581	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
696406003582	4Fe-4S binding domain; Region: Fer4_5; pfam12801
696406003583	4Fe-4S binding domain; Region: Fer4_5; pfam12801
696406003584	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
696406003585	hybrid sensory histidine kinase TorS; Provisional; Region: PRK11466
696406003586	HAMP domain; Region: HAMP; pfam00672
696406003587	dimerization interface [polypeptide binding]; other site
696406003588	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
696406003589	dimer interface [polypeptide binding]; other site
696406003590	phosphorylation site [posttranslational modification]
696406003591	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406003592	ATP binding site [chemical binding]; other site
696406003593	Mg2+ binding site [ion binding]; other site
696406003594	G-X-G motif; other site
696406003595	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406003596	active site
696406003597	phosphorylation site [posttranslational modification]
696406003598	intermolecular recognition site; other site
696406003599	dimerization interface [polypeptide binding]; other site
696406003600	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
696406003601	putative binding surface; other site
696406003602	active site
696406003603	TMAO reductase system periplasmic protein TorT; Provisional; Region: PRK10936
696406003604	TorT-like proteins, a periplasmic binding protein family that activates induction of the Tor respiratory system upon trimethylamine N-oxide (TMAO) electron-acceptor binding in bacteria; Region: PBP1_TorT-like; cd06306
696406003605	putative ligand binding site [chemical binding]; other site
696406003606	DNA-binding transcriptional regulator TorR; Provisional; Region: PRK10766
696406003607	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406003608	active site
696406003609	phosphorylation site [posttranslational modification]
696406003610	intermolecular recognition site; other site
696406003611	dimerization interface [polypeptide binding]; other site
696406003612	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
696406003613	DNA binding site [nucleotide binding]
696406003614	trimethylamine N-oxide reductase cytochrome c-type subunit; Provisional; Region: PRK15032
696406003615	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
696406003616	trimethylamine N-oxide reductase I catalytic subunit; Provisional; Region: PRK15102
696406003617	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
696406003618	molybdopterin cofactor binding site [chemical binding]; other site
696406003619	substrate binding site [chemical binding]; other site
696406003620	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
696406003621	molybdopterin cofactor binding site; other site
696406003622	chaperone protein TorD; Validated; Region: torD; PRK04976
696406003623	chaperone-modulator protein CbpM; Provisional; Region: PRK10265
696406003624	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
696406003625	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
696406003626	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
696406003627	HSP70 interaction site [polypeptide binding]; other site
696406003628	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
696406003629	substrate binding site [polypeptide binding]; other site
696406003630	dimer interface [polypeptide binding]; other site
696406003631	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
696406003632	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
696406003633	catalytic core [active]
696406003634	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
696406003635	hypothetical protein; Provisional; Region: PRK10174
696406003636	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
696406003637	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
696406003638	General stress protein [General function prediction only]; Region: GsiB; COG3729
696406003639	pyrimidine utilization transport protein G; Region: RutG; TIGR03616
696406003640	pyrimidine utilization flavin reductase protein F; Region: RutF; TIGR03615
696406003641	Nitroreductase-like family 5.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_5; cd02148
696406003642	putative FMN binding site [chemical binding]; other site
696406003643	pyrimidine utilization protein D; Region: RutD; TIGR03611
696406003644	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
696406003645	homotrimer interaction site [polypeptide binding]; other site
696406003646	putative active site [active]
696406003647	Isochorismatase family; Region: Isochorismatase; pfam00857
696406003648	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
696406003649	catalytic triad [active]
696406003650	conserved cis-peptide bond; other site
696406003651	pyrimidine utilization protein A; Region: RutA; TIGR03612
696406003652	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
696406003653	active site
696406003654	dimer interface [polypeptide binding]; other site
696406003655	non-prolyl cis peptide bond; other site
696406003656	insertion regions; other site
696406003657	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
696406003658	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
696406003659	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
696406003660	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
696406003661	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
696406003662	Predicted transcriptional regulator [Transcription]; Region: COG3905
696406003663	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
696406003664	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
696406003665	Glutamate binding site [chemical binding]; other site
696406003666	NAD binding site [chemical binding]; other site
696406003667	catalytic residues [active]
696406003668	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
696406003669	Na binding site [ion binding]; other site
696406003670	FTR1 family protein; Region: TIGR00145
696406003671	inactive ferrous ion transporter periplasmic protein EfeO; Provisional; Region: PRK10378
696406003672	Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473
696406003673	Imelysin; Region: Peptidase_M75; pfam09375
696406003674	Tat-translocated enzyme; Region: tat_substr_1; TIGR01412
696406003675	Predicted iron-dependent peroxidase [Inorganic ion transport and metabolism]; Region: COG2837
696406003676	hypothetical protein; Provisional; Region: PRK10536
696406003677	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
696406003678	Protein of unknown function (DUF2726); Region: DUF2726; pfam10881
696406003679	integrase; Provisional; Region: PRK09692
696406003680	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
696406003681	active site
696406003682	Int/Topo IB signature motif; other site
696406003683	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
696406003684	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
696406003685	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
696406003686	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4951
696406003687	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
696406003688	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
696406003689	ATP binding site [chemical binding]; other site
696406003690	putative Mg++ binding site [ion binding]; other site
696406003691	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
696406003692	nucleotide binding region [chemical binding]; other site
696406003693	ATP-binding site [chemical binding]; other site
696406003694	Dimerization/Docking domain of Cyclic GMP-dependent Protein Kinase I; Region: DD_cGKI; cl17044
696406003695	homodimer interface [polypeptide binding]; other site
696406003696	putative GKAP docking site [polypeptide binding]; other site
696406003697	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
696406003698	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
696406003699	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
696406003700	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
696406003701	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
696406003702	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
696406003703	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
696406003704	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
696406003705	DNA-binding interface [nucleotide binding]; DNA binding site
696406003706	Helix-turn-helix domain; Region: HTH_38; pfam13936
696406003707	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
696406003708	Integrase core domain; Region: rve; pfam00665
696406003709	Integrase core domain; Region: rve_3; pfam13683
696406003710	Enterobacterial TraT complement resistance protein; Region: TraT; pfam05818
696406003711	potential frameshift: common BLAST hit: gi|218691194|ref|YP_002399406.1| putative Restriction enzyme subunit beta
696406003712	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
696406003713	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
696406003714	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
696406003715	Sulfatase; Region: Sulfatase; pfam00884
696406003716	Urease accessory protein UreH [Posttranslational modification, protein turnover, chaperones]; Region: UreH; COG0829
696406003717	Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390
696406003718	alpha-gamma subunit interface [polypeptide binding]; other site
696406003719	beta-gamma subunit interface [polypeptide binding]; other site
696406003720	Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use of...; Region: Urease_beta; cd00407
696406003721	gamma-beta subunit interface [polypeptide binding]; other site
696406003722	alpha-beta subunit interface [polypeptide binding]; other site
696406003723	urease subunit alpha; Reviewed; Region: ureC; PRK13207
696406003724	Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375
696406003725	subunit interactions [polypeptide binding]; other site
696406003726	active site
696406003727	flap region; other site
696406003728	urease accessory protein UreE; Provisional; Region: ureE; PRK13261
696406003729	UreE urease accessory protein. UreE is a metallochaperone assisting the insertion of a Ni2+ ion in the active site of urease, an important step in the in vivo assembly of urease, an enzyme that hydrolyses urea into ammonia and carbamic acid. The...; Region: UreE; cd00571
696406003730	dimer interface [polypeptide binding]; other site
696406003731	catalytic residues [active]
696406003732	Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones]; Region: UreF; COG0830
696406003733	UreF; Region: UreF; pfam01730
696406003734	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
696406003735	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
696406003736	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
696406003737	Transposase; Region: HTH_Tnp_1; pfam01527
696406003738	conjugal transfer surface exclusion protein TraT; Provisional; Region: PRK13731
696406003739	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
696406003740	Hok/gef family; Region: HOK_GEF; pfam01848
696406003741	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
696406003742	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
696406003743	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
696406003744	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
696406003745	Transposase; Region: HTH_Tnp_1; pfam01527
696406003746	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
696406003747	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
696406003748	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
696406003749	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
696406003750	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
696406003751	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
696406003752	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
696406003753	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
696406003754	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
696406003755	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
696406003756	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
696406003757	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
696406003758	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
696406003759	Predicted transcriptional regulator [Transcription]; Region: COG2378
696406003760	Protein of unknown function (DUF4236); Region: DUF4236; pfam14020
696406003761	Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301
696406003762	Protein of unknown function (DUF2983); Region: DUF2983; pfam11202
696406003763	HAD-superfamily hydrolase, subfamily IIB; Region: HAD-SF-IIB; TIGR01484
696406003764	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
696406003765	active site
696406003766	Protein of unknown function (DUF3706); Region: DUF3706; pfam12500
696406003767	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
696406003768	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
696406003769	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
696406003770	putative metal binding site [ion binding]; other site
696406003771	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
696406003772	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
696406003773	putative metal binding site [ion binding]; other site
696406003774	Uncharacterized protein involved in stress response [General function prediction only]; Region: COG4110
696406003775	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
696406003776	putative metal binding site [ion binding]; other site
696406003777	tellurite resistance protein terB; Region: terB; cd07176
696406003778	putative metal binding site [ion binding]; other site
696406003779	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
696406003780	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
696406003781	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
696406003782	putative metal binding site [ion binding]; other site
696406003783	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
696406003784	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
696406003785	putative metal binding site [ion binding]; other site
696406003786	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
696406003787	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
696406003788	putative metal binding site [ion binding]; other site
696406003789	bifunctional enterobactin receptor/adhesin protein; Provisional; Region: PRK13486
696406003790	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
696406003791	N-terminal plug; other site
696406003792	ligand-binding site [chemical binding]; other site
696406003793	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
696406003794	Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819
696406003795	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
696406003796	homodimer interface [polypeptide binding]; other site
696406003797	TDP-binding site; other site
696406003798	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
696406003799	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
696406003800	Domain of unknown function (DUF4222); Region: DUF4222; pfam13973
696406003801	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
696406003802	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
696406003803	adhesin HecA family 20-residue repeat (two copies); Region: fil_hemag_20aa; TIGR01731
696406003804	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
696406003805	Part of AAA domain; Region: AAA_19; pfam13245
696406003806	AAA domain; Region: AAA_12; pfam13087
696406003807	Protein of unknown function (DUF2726); Region: DUF2726; pfam10881
696406003808	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
696406003809	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
696406003810	Active Sites [active]
696406003811	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
696406003812	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
696406003813	ParB-like nuclease domain; Region: ParB; smart00470
696406003814	PerC transcriptional activator; Region: PerC; pfam06069
696406003815	Homeodomain-like domain; Region: HTH_32; pfam13565
696406003816	Integrase core domain; Region: rve_3; cl15866
696406003817	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
696406003818	Transposase; Region: HTH_Tnp_1; pfam01527
696406003819	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
696406003820	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
696406003821	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
696406003822	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
696406003823	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
696406003824	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
696406003825	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
696406003826	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
696406003827	Transposase; Region: HTH_Tnp_1; pfam01527
696406003828	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
696406003829	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
696406003830	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
696406003831	hypothetical protein; Provisional; Region: PRK09945
696406003832	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
696406003833	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
696406003834	Autotransporter beta-domain; Region: Autotransporter; smart00869
696406003835	hypothetical protein; Provisional; Region: PRK09866
696406003836	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
696406003837	G1 box; other site
696406003838	GTP/Mg2+ binding site [chemical binding]; other site
696406003839	G2 box; other site
696406003840	Switch I region; other site
696406003841	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
696406003842	G3 box; other site
696406003843	Switch II region; other site
696406003844	GTP/Mg2+ binding site [chemical binding]; other site
696406003845	G4 box; other site
696406003846	G5 box; other site
696406003847	YjcZ-like protein; Region: YjcZ; pfam13990
696406003848	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
696406003849	nucleophile elbow; other site
696406003850	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
696406003851	Domain of unknown function (DUF4339); Region: DUF4339; pfam14237
696406003852	Domain of unknown function (DUF932); Region: DUF932; pfam06067
696406003853	Antirestriction protein; Region: Antirestrict; pfam03230
696406003854	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
696406003855	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
696406003856	MPN+ (JAMM) motif; other site
696406003857	Zinc-binding site [ion binding]; other site
696406003858	Protein of unknown function (DUF987); Region: DUF987; pfam06174
696406003859	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
696406003860	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
696406003861	Enterobacterial protein of unknown function (DUF957); Region: DUF957; pfam06117
696406003862	Methyltransferase domain; Region: Methyltransf_27; pfam13708
696406003863	bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469
696406003864	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
696406003865	putative ligand binding site [chemical binding]; other site
696406003866	NAD binding site [chemical binding]; other site
696406003867	dimerization interface [polypeptide binding]; other site
696406003868	catalytic site [active]
696406003869	putative hydrolase; Validated; Region: PRK09248
696406003870	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
696406003871	active site
696406003872	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
696406003873	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
696406003874	curli production assembly/transport protein CsgG; Provisional; Region: PRK15184
696406003875	curli assembly protein CsgF; Provisional; Region: PRK10050
696406003876	curli assembly protein CsgE; Provisional; Region: PRK10386
696406003877	DNA-binding transcriptional regulator CsgD; Provisional; Region: PRK10100
696406003878	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
696406003879	DNA binding residues [nucleotide binding]
696406003880	dimerization interface [polypeptide binding]; other site
696406003881	curlin minor subunit CsgB; Provisional; Region: csgB; PRK10101
696406003882	Curlin associated repeat; Region: Curlin_rpt; pfam07012
696406003883	Curlin associated repeat; Region: Curlin_rpt; pfam07012
696406003884	major curlin subunit; Provisional; Region: csgA; PRK10051
696406003885	Curlin associated repeat; Region: Curlin_rpt; pfam07012
696406003886	Curlin associated repeat; Region: Curlin_rpt; pfam07012
696406003887	curli assembly protein CsgC; Provisional; Region: csgC; PRK10102
696406003888	Fimbrial protein; Region: Fimbrial; cl01416
696406003889	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
696406003890	putative ADP-ribose binding site [chemical binding]; other site
696406003891	putative active site [active]
696406003892	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
696406003893	PLD-like domain; Region: PLDc_2; pfam13091
696406003894	putative active site [active]
696406003895	catalytic site [active]
696406003896	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
696406003897	PLD-like domain; Region: PLDc_2; pfam13091
696406003898	putative active site [active]
696406003899	catalytic site [active]
696406003900	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
696406003901	Acyltransferase family; Region: Acyl_transf_3; pfam01757
696406003902	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
696406003903	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; pfam04349
696406003904	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
696406003905	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
696406003906	Ligand binding site; other site
696406003907	DXD motif; other site
696406003908	lipoprotein; Provisional; Region: PRK10175
696406003909	secY/secA suppressor protein; Provisional; Region: PRK11467
696406003910	drug efflux system protein MdtG; Provisional; Region: PRK09874
696406003911	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406003912	putative substrate translocation pore; other site
696406003913	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
696406003914	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
696406003915	putative acyl-acceptor binding pocket; other site
696406003916	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
696406003917	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
696406003918	active site residue [active]
696406003919	hypothetical protein; Provisional; Region: PRK03757
696406003920	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
696406003921	Protein of unknown function (DUF2770); Region: DUF2770; pfam10968
696406003922	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
696406003923	hydroxyglutarate oxidase; Provisional; Region: PRK11728
696406003924	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
696406003925	DNA damage-inducible protein I; Provisional; Region: PRK10597
696406003926	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
696406003927	active site
696406003928	substrate binding pocket [chemical binding]; other site
696406003929	dimer interface [polypeptide binding]; other site
696406003930	lipoprotein; Provisional; Region: PRK10598
696406003931	glutaredoxin 2; Provisional; Region: PRK10387
696406003932	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
696406003933	C-terminal domain interface [polypeptide binding]; other site
696406003934	GSH binding site (G-site) [chemical binding]; other site
696406003935	catalytic residues [active]
696406003936	putative dimer interface [polypeptide binding]; other site
696406003937	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
696406003938	N-terminal domain interface [polypeptide binding]; other site
696406003939	multidrug resistance protein MdtH; Provisional; Region: PRK11646
696406003940	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406003941	putative substrate translocation pore; other site
696406003942	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
696406003943	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
696406003944	hypothetical protein; Provisional; Region: PRK11239
696406003945	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3132
696406003946	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
696406003947	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
696406003948	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
696406003949	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
696406003950	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
696406003951	flagella synthesis chaperone protein FlgN; Provisional; Region: PRK15459
696406003952	anti-sigma28 factor FlgM; Provisional; Region: PRK10810
696406003953	flagellar basal body P-ring biosynthesis protein FlgA; Reviewed; Region: flgA; PRK07018
696406003954	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
696406003955	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
696406003956	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
696406003957	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
696406003958	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
696406003959	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
696406003960	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
696406003961	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06655
696406003962	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
696406003963	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
696406003964	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
696406003965	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
696406003966	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
696406003967	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
696406003968	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgF; COG4787
696406003969	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
696406003970	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
696406003971	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
696406003972	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
696406003973	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
696406003974	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
696406003975	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
696406003976	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
696406003977	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
696406003978	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
696406003979	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
696406003980	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
696406003981	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
696406003982	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
696406003983	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
696406003984	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
696406003985	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
696406003986	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
696406003987	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
696406003988	homodimer interface [polypeptide binding]; other site
696406003989	oligonucleotide binding site [chemical binding]; other site
696406003990	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
696406003991	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
696406003992	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
696406003993	RNA binding surface [nucleotide binding]; other site
696406003994	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
696406003995	active site
696406003996	Maf-like protein; Region: Maf; pfam02545
696406003997	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
696406003998	active site
696406003999	dimer interface [polypeptide binding]; other site
696406004000	hypothetical protein; Provisional; Region: PRK11193
696406004001	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
696406004002	putative phosphate acyltransferase; Provisional; Region: PRK05331
696406004003	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
696406004004	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
696406004005	dimer interface [polypeptide binding]; other site
696406004006	active site
696406004007	CoA binding pocket [chemical binding]; other site
696406004008	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
696406004009	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
696406004010	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
696406004011	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
696406004012	NAD(P) binding site [chemical binding]; other site
696406004013	homotetramer interface [polypeptide binding]; other site
696406004014	homodimer interface [polypeptide binding]; other site
696406004015	active site
696406004016	acyl carrier protein; Provisional; Region: acpP; PRK00982
696406004017	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
696406004018	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
696406004019	dimer interface [polypeptide binding]; other site
696406004020	active site
696406004021	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
696406004022	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
696406004023	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406004024	catalytic residue [active]
696406004025	conserved hypothetical protein, YceG family; Region: TIGR00247
696406004026	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
696406004027	dimerization interface [polypeptide binding]; other site
696406004028	thymidylate kinase; Validated; Region: tmk; PRK00698
696406004029	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
696406004030	TMP-binding site; other site
696406004031	ATP-binding site [chemical binding]; other site
696406004032	DNA polymerase III subunit delta'; Validated; Region: PRK07993
696406004033	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
696406004034	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
696406004035	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
696406004036	active site
696406004037	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
696406004038	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
696406004039	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
696406004040	active site turn [active]
696406004041	phosphorylation site [posttranslational modification]
696406004042	ferric-rhodotorulic acid outer membrane transporter; Provisional; Region: PRK10003
696406004043	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
696406004044	N-terminal plug; other site
696406004045	ligand-binding site [chemical binding]; other site
696406004046	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
696406004047	nucleotide binding site/active site [active]
696406004048	HIT family signature motif; other site
696406004049	catalytic residue [active]
696406004050	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
696406004051	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
696406004052	putative dimer interface [polypeptide binding]; other site
696406004053	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
696406004054	thiamine kinase; Region: ycfN_thiK; TIGR02721
696406004055	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
696406004056	active site
696406004057	substrate binding site [chemical binding]; other site
696406004058	ATP binding site [chemical binding]; other site
696406004059	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
696406004060	beta-hexosaminidase; Provisional; Region: PRK05337
696406004061	hypothetical protein; Provisional; Region: PRK04940
696406004062	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
696406004063	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
696406004064	hypothetical protein; Provisional; Region: PRK11280
696406004065	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
696406004066	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
696406004067	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
696406004068	L,D-transpeptidase; Provisional; Region: PRK10260
696406004069	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
696406004070	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
696406004071	transcription-repair coupling factor; Provisional; Region: PRK10689
696406004072	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
696406004073	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
696406004074	ATP binding site [chemical binding]; other site
696406004075	putative Mg++ binding site [ion binding]; other site
696406004076	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
696406004077	nucleotide binding region [chemical binding]; other site
696406004078	ATP-binding site [chemical binding]; other site
696406004079	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
696406004080	Predicted membrane protein [Function unknown]; Region: COG4763
696406004081	Acyltransferase family; Region: Acyl_transf_3; pfam01757
696406004082	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
696406004083	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
696406004084	FtsX-like permease family; Region: FtsX; pfam02687
696406004085	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
696406004086	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
696406004087	Walker A/P-loop; other site
696406004088	ATP binding site [chemical binding]; other site
696406004089	Q-loop/lid; other site
696406004090	ABC transporter signature motif; other site
696406004091	Walker B; other site
696406004092	D-loop; other site
696406004093	H-loop/switch region; other site
696406004094	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
696406004095	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
696406004096	FtsX-like permease family; Region: FtsX; pfam02687
696406004097	fructokinase; Reviewed; Region: PRK09557
696406004098	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
696406004099	nucleotide binding site [chemical binding]; other site
696406004100	NAD-dependent deacetylase; Provisional; Region: PRK00481
696406004101	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
696406004102	NAD+ binding site [chemical binding]; other site
696406004103	substrate binding site [chemical binding]; other site
696406004104	Zn binding site [ion binding]; other site
696406004105	Repair protein; Region: Repair_PSII; cl01535
696406004106	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
696406004107	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
696406004108	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
696406004109	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
696406004110	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406004111	dimer interface [polypeptide binding]; other site
696406004112	conserved gate region; other site
696406004113	putative PBP binding loops; other site
696406004114	ABC-ATPase subunit interface; other site
696406004115	Predicted membrane protein (DUF2335); Region: DUF2335; cl02210
696406004116	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
696406004117	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
696406004118	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
696406004119	dimer interface [polypeptide binding]; other site
696406004120	active site
696406004121	Int/Topo IB signature motif; other site
696406004122	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
696406004123	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
696406004124	active site
696406004125	catalytic site [active]
696406004126	substrate binding site [chemical binding]; other site
696406004127	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
696406004128	DicB protein; Region: DicB; pfam05358
696406004129	transcriptional repressor DicA; Reviewed; Region: PRK09706
696406004130	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
696406004131	primosomal protein DnaI; Provisional; Region: PRK02854
696406004132	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
696406004133	Protein of unknown function (DUF968); Region: DUF968; pfam06147
696406004134	Holliday junction resolvase [DNA replication, recombination, and repair]; Region: Rus; COG4570
696406004135	Phage antitermination protein Q; Region: Phage_antiter_Q; pfam06323
696406004136	Protein of unknown function (DUF754); Region: DUF754; pfam05449
696406004137	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539
696406004138	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
696406004139	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
696406004140	active site
696406004141	Phage terminase, small subunit; Region: Terminase_4; pfam05119
696406004142	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
696406004143	Phage-related protein [Function unknown]; Region: COG4695
696406004144	Phage portal protein; Region: Phage_portal; pfam04860
696406004145	phage prohead protease, HK97 family; Region: proheadase_HK97; TIGR01543
696406004146	Biogenesis of lysosome-related organelles complex-1 subunit 2; Region: BLOC1_2; pfam10046
696406004147	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
696406004148	Phage capsid family; Region: Phage_capsid; pfam05065
696406004149	Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054
696406004150	oligomerization interface [polypeptide binding]; other site
696406004151	Bacteriophage head-tail adaptor [General function prediction only]; Region: COG5614
696406004152	phage protein, HK97 gp10 family; Region: phge_HK97_gp10; TIGR01725
696406004153	Protein of unknown function (DUF3168); Region: DUF3168; pfam11367
696406004154	Phage tail assembly chaperone; Region: Phage_TAC; pfam06222
696406004155	Protein of unknown function (DUF4035); Region: DUF4035; pfam13227
696406004156	Phage minor tail protein; Region: Phage_min_tail; pfam05939
696406004157	Phage-related protein [Function unknown]; Region: gp18; COG4672
696406004158	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
696406004159	MPN+ (JAMM) motif; other site
696406004160	Zinc-binding site [ion binding]; other site
696406004161	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
696406004162	NlpC/P60 family; Region: NLPC_P60; cl17555
696406004163	Phage-related protein, tail component [Function unknown]; Region: COG4723
696406004164	Phage-related protein, tail component [Function unknown]; Region: COG4733
696406004165	Putative phage tail protein; Region: Phage-tail_3; pfam13550
696406004166	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
696406004167	Fibronectin type III protein; Region: DUF3672; pfam12421
696406004168	Enterobacterial Ail/Lom protein; Region: Ail_Lom; pfam06316
696406004169	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
696406004170	Phage Tail Collar Domain; Region: Collar; pfam07484
696406004171	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
696406004172	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
696406004173	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
696406004174	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
696406004175	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406004176	dimer interface [polypeptide binding]; other site
696406004177	conserved gate region; other site
696406004178	putative PBP binding loops; other site
696406004179	ABC-ATPase subunit interface; other site
696406004180	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
696406004181	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
696406004182	Walker A/P-loop; other site
696406004183	ATP binding site [chemical binding]; other site
696406004184	Q-loop/lid; other site
696406004185	ABC transporter signature motif; other site
696406004186	Walker B; other site
696406004187	D-loop; other site
696406004188	H-loop/switch region; other site
696406004189	TOBE domain; Region: TOBE_2; pfam08402
696406004190	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
696406004191	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
696406004192	metal binding site [ion binding]; metal-binding site
696406004193	dimer interface [polypeptide binding]; other site
696406004194	Uncharacterized conserved protein [Function unknown]; Region: COG2850
696406004195	Cupin-like domain; Region: Cupin_8; pfam13621
696406004196	sensor protein PhoQ; Provisional; Region: PRK10815
696406004197	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
696406004198	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
696406004199	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
696406004200	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406004201	ATP binding site [chemical binding]; other site
696406004202	Mg2+ binding site [ion binding]; other site
696406004203	G-X-G motif; other site
696406004204	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
696406004205	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406004206	active site
696406004207	phosphorylation site [posttranslational modification]
696406004208	intermolecular recognition site; other site
696406004209	dimerization interface [polypeptide binding]; other site
696406004210	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
696406004211	DNA binding site [nucleotide binding]
696406004212	adenylosuccinate lyase; Provisional; Region: PRK09285
696406004213	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
696406004214	tetramer interface [polypeptide binding]; other site
696406004215	active site
696406004216	putative lysogenization regulator; Reviewed; Region: PRK00218
696406004217	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
696406004218	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
696406004219	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
696406004220	nudix motif; other site
696406004221	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
696406004222	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
696406004223	probable active site [active]
696406004224	isocitrate dehydrogenase; Validated; Region: PRK07362
696406004225	isocitrate dehydrogenase; Reviewed; Region: PRK07006
696406004226	Protein of unknown function (DUF1398); Region: DUF1398; pfam07166
696406004227	transcriptional regulator MirA; Provisional; Region: PRK15043
696406004228	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
696406004229	DNA binding residues [nucleotide binding]
696406004230	Sensors of blue-light using FAD; Region: BLUF; smart01034
696406004231	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
696406004232	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
696406004233	potential frameshift: common BLAST hit: gi|218694679|ref|YP_002402346.1| inner membrane protein
696406004234	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
696406004235	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
696406004236	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
696406004237	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
696406004238	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
696406004239	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
696406004240	cell division inhibitor MinD; Provisional; Region: PRK10818
696406004241	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
696406004242	Switch I; other site
696406004243	Switch II; other site
696406004244	septum formation inhibitor; Reviewed; Region: minC; PRK03511
696406004245	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
696406004246	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
696406004247	Fels-1 Prophage Protein-like; Region: Fels1; pfam05666
696406004248	Fels-1 Prophage Protein-like; Region: Fels1; pfam05666
696406004249	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
696406004250	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
696406004251	hypothetical protein; Provisional; Region: PRK10691
696406004252	hypothetical protein; Provisional; Region: PRK05170
696406004253	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
696406004254	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
696406004255	Catalytic site [active]
696406004256	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
696406004257	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
696406004258	active site
696406004259	DNA binding site [nucleotide binding]
696406004260	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
696406004261	disulfide bond formation protein B; Provisional; Region: PRK01749
696406004262	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
696406004263	transmembrane helices; other site
696406004264	fatty acid metabolism regulator; Provisional; Region: PRK04984
696406004265	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
696406004266	DNA-binding site [nucleotide binding]; DNA binding site
696406004267	FadR C-terminal domain; Region: FadR_C; pfam07840
696406004268	SpoVR family protein; Provisional; Region: PRK11767
696406004269	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
696406004270	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
696406004271	alanine racemase; Reviewed; Region: dadX; PRK03646
696406004272	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
696406004273	active site
696406004274	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
696406004275	substrate binding site [chemical binding]; other site
696406004276	catalytic residues [active]
696406004277	dimer interface [polypeptide binding]; other site
696406004278	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
696406004279	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
696406004280	TrkA-C domain; Region: TrkA_C; pfam02080
696406004281	Transporter associated domain; Region: CorC_HlyC; smart01091
696406004282	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
696406004283	dimer interface [polypeptide binding]; other site
696406004284	catalytic triad [active]
696406004285	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
696406004286	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
696406004287	N-acetyl-D-glucosamine binding site [chemical binding]; other site
696406004288	catalytic residue [active]
696406004289	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
696406004290	Flagellar regulator YcgR; Region: YcgR; pfam07317
696406004291	PilZ domain; Region: PilZ; pfam07238
696406004292	hypothetical protein; Provisional; Region: PRK10457
696406004293	trehalase; Provisional; Region: treA; PRK13271
696406004294	Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626
696406004295	dihydroxyacetone kinase subunit M; Provisional; Region: PRK11377
696406004296	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3412
696406004297	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
696406004298	dimerization domain swap beta strand [polypeptide binding]; other site
696406004299	regulatory protein interface [polypeptide binding]; other site
696406004300	active site
696406004301	regulatory phosphorylation site [posttranslational modification]; other site
696406004302	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
696406004303	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
696406004304	dihydroxyacetone kinase subunit DhaL; Provisional; Region: PRK10005
696406004305	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK11468
696406004306	Dak1 domain; Region: Dak1; pfam02733
696406004307	DNA-binding transcriptional regulator DhaR; Provisional; Region: PRK11388
696406004308	PAS domain; Region: PAS; smart00091
696406004309	putative active site [active]
696406004310	heme pocket [chemical binding]; other site
696406004311	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406004312	Walker A motif; other site
696406004313	ATP binding site [chemical binding]; other site
696406004314	Walker B motif; other site
696406004315	arginine finger; other site
696406004316	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
696406004317	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
696406004318	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
696406004319	Autotransporter beta-domain; Region: Autotransporter; pfam03797
696406004320	GTP-binding protein YchF; Reviewed; Region: PRK09601
696406004321	YchF GTPase; Region: YchF; cd01900
696406004322	G1 box; other site
696406004323	GTP/Mg2+ binding site [chemical binding]; other site
696406004324	Switch I region; other site
696406004325	G2 box; other site
696406004326	Switch II region; other site
696406004327	G3 box; other site
696406004328	G4 box; other site
696406004329	G5 box; other site
696406004330	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
696406004331	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
696406004332	putative active site [active]
696406004333	catalytic residue [active]
696406004334	hypothetical protein; Provisional; Region: PRK10692
696406004335	putative transporter; Provisional; Region: PRK11660
696406004336	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
696406004337	Sulfate transporter family; Region: Sulfate_transp; pfam00916
696406004338	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
696406004339	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
696406004340	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
696406004341	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
696406004342	active site
696406004343	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
696406004344	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
696406004345	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
696406004346	outer membrane lipoprotein LolB; Region: lolB; TIGR00548
696406004347	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
696406004348	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
696406004349	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
696406004350	tRNA; other site
696406004351	putative tRNA binding site [nucleotide binding]; other site
696406004352	putative NADP binding site [chemical binding]; other site
696406004353	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
696406004354	peptide chain release factor 1; Validated; Region: prfA; PRK00591
696406004355	This domain is found in peptide chain release factors; Region: PCRF; smart00937
696406004356	RF-1 domain; Region: RF-1; pfam00472
696406004357	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
696406004358	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406004359	hypothetical protein; Provisional; Region: PRK10278
696406004360	hypothetical protein; Provisional; Region: PRK10941
696406004361	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
696406004362	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
696406004363	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
696406004364	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
696406004365	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
696406004366	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
696406004367	calcium/sodium:proton antiporter; Provisional; Region: PRK10599
696406004368	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
696406004369	cation transport regulator; Reviewed; Region: chaB; PRK09582
696406004370	Uncharacterized protein involved in cation transport [Inorganic ion transport and metabolism]; Region: ChaC; COG3703
696406004371	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
696406004372	putative active site pocket [active]
696406004373	dimerization interface [polypeptide binding]; other site
696406004374	putative catalytic residue [active]
696406004375	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
696406004376	putative invasin; Provisional; Region: PRK10177
696406004377	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
696406004378	transcriptional regulator NarL; Provisional; Region: PRK10651
696406004379	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406004380	active site
696406004381	phosphorylation site [posttranslational modification]
696406004382	intermolecular recognition site; other site
696406004383	dimerization interface [polypeptide binding]; other site
696406004384	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
696406004385	DNA binding residues [nucleotide binding]
696406004386	dimerization interface [polypeptide binding]; other site
696406004387	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
696406004388	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
696406004389	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
696406004390	dimerization interface [polypeptide binding]; other site
696406004391	Histidine kinase; Region: HisKA_3; pfam07730
696406004392	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406004393	ATP binding site [chemical binding]; other site
696406004394	Mg2+ binding site [ion binding]; other site
696406004395	G-X-G motif; other site
696406004396	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
696406004397	respiratory nitrate reductase, alpha subunit; Region: narG; TIGR01580
696406004398	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
696406004399	[4Fe-4S] binding site [ion binding]; other site
696406004400	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
696406004401	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
696406004402	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
696406004403	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
696406004404	molybdopterin cofactor binding site; other site
696406004405	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
696406004406	4Fe-4S binding domain; Region: Fer4; cl02805
696406004407	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
696406004408	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
696406004409	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
696406004410	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
696406004411	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
696406004412	putative active site [active]
696406004413	putative substrate binding site [chemical binding]; other site
696406004414	putative cosubstrate binding site; other site
696406004415	catalytic site [active]
696406004416	hypothetical protein; Provisional; Region: PRK01617
696406004417	hypothetical protein; Provisional; Region: PRK10279
696406004418	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
696406004419	active site
696406004420	nucleophile elbow; other site
696406004421	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406004422	active site
696406004423	response regulator of RpoS; Provisional; Region: PRK10693
696406004424	phosphorylation site [posttranslational modification]
696406004425	intermolecular recognition site; other site
696406004426	dimerization interface [polypeptide binding]; other site
696406004427	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
696406004428	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
696406004429	active site
696406004430	tetramer interface; other site
696406004431	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
696406004432	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
696406004433	thymidine kinase; Provisional; Region: PRK04296
696406004434	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
696406004435	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
696406004436	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
696406004437	putative catalytic cysteine [active]
696406004438	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
696406004439	putative active site [active]
696406004440	metal binding site [ion binding]; metal-binding site
696406004441	hypothetical protein; Provisional; Region: PRK11111
696406004442	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
696406004443	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
696406004444	peptide binding site [polypeptide binding]; other site
696406004445	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
696406004446	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406004447	dimer interface [polypeptide binding]; other site
696406004448	conserved gate region; other site
696406004449	putative PBP binding loops; other site
696406004450	ABC-ATPase subunit interface; other site
696406004451	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
696406004452	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
696406004453	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406004454	dimer interface [polypeptide binding]; other site
696406004455	conserved gate region; other site
696406004456	putative PBP binding loops; other site
696406004457	ABC-ATPase subunit interface; other site
696406004458	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
696406004459	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
696406004460	Walker A/P-loop; other site
696406004461	ATP binding site [chemical binding]; other site
696406004462	Q-loop/lid; other site
696406004463	ABC transporter signature motif; other site
696406004464	Walker B; other site
696406004465	D-loop; other site
696406004466	H-loop/switch region; other site
696406004467	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
696406004468	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
696406004469	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
696406004470	Walker A/P-loop; other site
696406004471	ATP binding site [chemical binding]; other site
696406004472	Q-loop/lid; other site
696406004473	ABC transporter signature motif; other site
696406004474	Walker B; other site
696406004475	D-loop; other site
696406004476	H-loop/switch region; other site
696406004477	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
696406004478	dsDNA-mimic protein; Reviewed; Region: PRK05094
696406004479	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
696406004480	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
696406004481	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
696406004482	putative active site [active]
696406004483	catalytic site [active]
696406004484	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
696406004485	putative active site [active]
696406004486	catalytic site [active]
696406004487	voltage-gated potassium channel; Provisional; Region: PRK10537
696406004488	Ion channel; Region: Ion_trans_2; pfam07885
696406004489	TrkA-N domain; Region: TrkA_N; pfam02254
696406004490	YciI-like protein; Reviewed; Region: PRK11370
696406004491	multiple promoter invertase; Provisional; Region: mpi; PRK13413
696406004492	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
696406004493	catalytic residues [active]
696406004494	catalytic nucleophile [active]
696406004495	Presynaptic Site I dimer interface [polypeptide binding]; other site
696406004496	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
696406004497	Synaptic Flat tetramer interface [polypeptide binding]; other site
696406004498	Synaptic Site I dimer interface [polypeptide binding]; other site
696406004499	DNA binding site [nucleotide binding]
696406004500	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
696406004501	DNA-binding interface [nucleotide binding]; DNA binding site
696406004502	Helix-turn-helix domain; Region: HTH_36; pfam13730
696406004503	RF-1 domain; Region: RF-1; cl17422
696406004504	tape measure domain; Region: tape_meas_nterm; TIGR02675
696406004505	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
696406004506	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
696406004507	catalytic residues [active]
696406004508	catalytic nucleophile [active]
696406004509	Recombinase; Region: Recombinase; pfam07508
696406004510	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
696406004511	transport protein TonB; Provisional; Region: PRK10819
696406004512	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
696406004513	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
696406004514	intracellular septation protein A; Reviewed; Region: PRK00259
696406004515	hypothetical protein; Provisional; Region: PRK02868
696406004516	outer membrane protein W; Provisional; Region: PRK10959
696406004517	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3685
696406004518	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
696406004519	dimerization interface [polypeptide binding]; other site
696406004520	metal binding site [ion binding]; metal-binding site
696406004521	General stress protein [General function prediction only]; Region: GsiB; COG3729
696406004522	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
696406004523	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
696406004524	substrate binding site [chemical binding]; other site
696406004525	active site
696406004526	catalytic residues [active]
696406004527	heterodimer interface [polypeptide binding]; other site
696406004528	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
696406004529	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
696406004530	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406004531	catalytic residue [active]
696406004532	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
696406004533	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
696406004534	active site
696406004535	ribulose/triose binding site [chemical binding]; other site
696406004536	phosphate binding site [ion binding]; other site
696406004537	substrate (anthranilate) binding pocket [chemical binding]; other site
696406004538	product (indole) binding pocket [chemical binding]; other site
696406004539	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
696406004540	active site
696406004541	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK09522
696406004542	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
696406004543	glutamine binding [chemical binding]; other site
696406004544	catalytic triad [active]
696406004545	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
696406004546	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
696406004547	anthranilate synthase component I; Provisional; Region: PRK13564
696406004548	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
696406004549	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
696406004550	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
696406004551	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
696406004552	active site
696406004553	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
696406004554	hypothetical protein; Provisional; Region: PRK11630
696406004555	Predicted membrane protein (DUF2207); Region: DUF2207; pfam09972
696406004556	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
696406004557	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
696406004558	RNA binding surface [nucleotide binding]; other site
696406004559	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
696406004560	probable active site [active]
696406004561	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
696406004562	Cob(I)alamin adenosyltransferase N terminal; Region: Co_AT_N; pfam12557
696406004563	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
696406004564	homodimer interface [polypeptide binding]; other site
696406004565	Walker A motif; other site
696406004566	ATP binding site [chemical binding]; other site
696406004567	hydroxycobalamin binding site [chemical binding]; other site
696406004568	Walker B motif; other site
696406004569	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
696406004570	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
696406004571	NADP binding site [chemical binding]; other site
696406004572	homodimer interface [polypeptide binding]; other site
696406004573	active site
696406004574	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
696406004575	putative inner membrane peptidase; Provisional; Region: PRK11778
696406004576	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
696406004577	tandem repeat interface [polypeptide binding]; other site
696406004578	oligomer interface [polypeptide binding]; other site
696406004579	active site residues [active]
696406004580	hypothetical protein; Provisional; Region: PRK11037
696406004581	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
696406004582	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
696406004583	active site
696406004584	interdomain interaction site; other site
696406004585	putative metal-binding site [ion binding]; other site
696406004586	nucleotide binding site [chemical binding]; other site
696406004587	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
696406004588	domain I; other site
696406004589	DNA binding groove [nucleotide binding]
696406004590	phosphate binding site [ion binding]; other site
696406004591	domain II; other site
696406004592	domain III; other site
696406004593	nucleotide binding site [chemical binding]; other site
696406004594	catalytic site [active]
696406004595	domain IV; other site
696406004596	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
696406004597	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
696406004598	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
696406004599	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
696406004600	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
696406004601	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406004602	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
696406004603	substrate binding site [chemical binding]; other site
696406004604	putative dimerization interface [polypeptide binding]; other site
696406004605	aconitate hydratase; Validated; Region: PRK09277
696406004606	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
696406004607	substrate binding site [chemical binding]; other site
696406004608	ligand binding site [chemical binding]; other site
696406004609	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
696406004610	substrate binding site [chemical binding]; other site
696406004611	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
696406004612	dimerization interface [polypeptide binding]; other site
696406004613	active site
696406004614	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
696406004615	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
696406004616	active site
696406004617	Predicted membrane protein [Function unknown]; Region: COG3771
696406004618	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
696406004619	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
696406004620	TPR motif; other site
696406004621	binding surface
696406004622	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
696406004623	binding surface
696406004624	TPR motif; other site
696406004625	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
696406004626	active site
696406004627	dimer interface [polypeptide binding]; other site
696406004628	translation initiation factor Sui1; Validated; Region: PRK06824
696406004629	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
696406004630	putative rRNA binding site [nucleotide binding]; other site
696406004631	lipoprotein; Provisional; Region: PRK10540
696406004632	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
696406004633	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
696406004634	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
696406004635	hypothetical protein; Provisional; Region: PRK13658
696406004636	RNase II stability modulator; Provisional; Region: PRK10060
696406004637	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
696406004638	putative active site [active]
696406004639	heme pocket [chemical binding]; other site
696406004640	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
696406004641	metal binding site [ion binding]; metal-binding site
696406004642	active site
696406004643	I-site; other site
696406004644	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
696406004645	exoribonuclease II; Provisional; Region: PRK05054
696406004646	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
696406004647	RNB domain; Region: RNB; pfam00773
696406004648	S1 RNA binding domain; Region: S1; pfam00575
696406004649	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950
696406004650	Uncharacterized conserved protein [Function unknown]; Region: COG2128
696406004651	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
696406004652	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
696406004653	NAD binding site [chemical binding]; other site
696406004654	homotetramer interface [polypeptide binding]; other site
696406004655	homodimer interface [polypeptide binding]; other site
696406004656	substrate binding site [chemical binding]; other site
696406004657	active site
696406004658	Domain of unknown function, appears to be related to a diverse group of endonucleases; Region: Endonuclease_DUF559; cd01038
696406004659	putative active site [active]
696406004660	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
696406004661	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
696406004662	Walker A/P-loop; other site
696406004663	ATP binding site [chemical binding]; other site
696406004664	Q-loop/lid; other site
696406004665	ABC transporter signature motif; other site
696406004666	Walker B; other site
696406004667	D-loop; other site
696406004668	H-loop/switch region; other site
696406004669	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
696406004670	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
696406004671	Walker A/P-loop; other site
696406004672	ATP binding site [chemical binding]; other site
696406004673	Q-loop/lid; other site
696406004674	ABC transporter signature motif; other site
696406004675	Walker B; other site
696406004676	D-loop; other site
696406004677	H-loop/switch region; other site
696406004678	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
696406004679	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
696406004680	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
696406004681	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406004682	dimer interface [polypeptide binding]; other site
696406004683	conserved gate region; other site
696406004684	putative PBP binding loops; other site
696406004685	ABC-ATPase subunit interface; other site
696406004686	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
696406004687	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406004688	dimer interface [polypeptide binding]; other site
696406004689	conserved gate region; other site
696406004690	putative PBP binding loops; other site
696406004691	ABC-ATPase subunit interface; other site
696406004692	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
696406004693	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
696406004694	peptide binding site [polypeptide binding]; other site
696406004695	Protein of unknown function (DUF2543); Region: DUF2543; pfam10820
696406004696	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
696406004697	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
696406004698	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
696406004699	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
696406004700	gamma-glutamyl-gamma-aminobutyrate hydrolase; Provisional; Region: puuD; PRK11366
696406004701	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
696406004702	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
696406004703	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
696406004704	non-specific DNA binding site [nucleotide binding]; other site
696406004705	salt bridge; other site
696406004706	sequence-specific DNA binding site [nucleotide binding]; other site
696406004707	Cupin domain; Region: Cupin_2; pfam07883
696406004708	gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK09847
696406004709	Escherichia coli NADP+-dependent gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase PuuC-like; Region: ALDH_GABALDH-PuuC; cd07112
696406004710	NAD(P) binding site [chemical binding]; other site
696406004711	catalytic residues [active]
696406004712	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
696406004713	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
696406004714	4-aminobutyrate transaminase; Provisional; Region: PRK09792
696406004715	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
696406004716	inhibitor-cofactor binding pocket; inhibition site
696406004717	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406004718	catalytic residue [active]
696406004719	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
696406004720	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406004721	Walker A motif; other site
696406004722	ATP binding site [chemical binding]; other site
696406004723	Walker B motif; other site
696406004724	arginine finger; other site
696406004725	phage shock protein PspA; Provisional; Region: PRK10698
696406004726	phage shock protein B; Provisional; Region: pspB; PRK09458
696406004727	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
696406004728	phage shock protein C; Region: phageshock_pspC; TIGR02978
696406004729	peripheral inner membrane phage-shock protein; Provisional; Region: PRK10497
696406004730	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
696406004731	active site residue [active]
696406004732	Alpha amylase catalytic domain found in sucrose phosphorylase-like proteins (also called sucrose glucosyltransferase, disaccharide glucosyltransferase, and sucrose-phosphate alpha-D glucosyltransferase); Region: AmyAc_Sucrose_phosphorylase-like_1; cd11356
696406004733	sucrose phosphorylase; Provisional; Region: PRK13840
696406004734	active site
696406004735	homodimer interface [polypeptide binding]; other site
696406004736	catalytic site [active]
696406004737	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
696406004738	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
696406004739	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
696406004740	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406004741	dimer interface [polypeptide binding]; other site
696406004742	conserved gate region; other site
696406004743	putative PBP binding loops; other site
696406004744	ABC-ATPase subunit interface; other site
696406004745	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
696406004746	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406004747	dimer interface [polypeptide binding]; other site
696406004748	conserved gate region; other site
696406004749	putative PBP binding loops; other site
696406004750	ABC-ATPase subunit interface; other site
696406004751	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
696406004752	2-desacetyl-2-hydroxyethyl bacteriochlorophyllide and other MDR family members; Region: 2-desacetyl-2-hydroxyethyl_bacteriochlorophyllide_; cd08255
696406004753	putative NAD(P) binding site [chemical binding]; other site
696406004754	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
696406004755	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
696406004756	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
696406004757	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
696406004758	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
696406004759	Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]; Region: ATH1; COG1554
696406004760	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
696406004761	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
696406004762	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
696406004763	beta-phosphoglucomutase; Region: bPGM; TIGR01990
696406004764	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696406004765	motif II; other site
696406004766	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
696406004767	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
696406004768	Walker A/P-loop; other site
696406004769	ATP binding site [chemical binding]; other site
696406004770	Q-loop/lid; other site
696406004771	ABC transporter signature motif; other site
696406004772	Walker B; other site
696406004773	D-loop; other site
696406004774	H-loop/switch region; other site
696406004775	TOBE domain; Region: TOBE_2; pfam08402
696406004776	Outer membrane protein G (OmpG); Region: Porin_OmpG; pfam09381
696406004777	Transcriptional regulators [Transcription]; Region: PurR; COG1609
696406004778	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
696406004779	DNA binding site [nucleotide binding]
696406004780	domain linker motif; other site
696406004781	Ligand-binding domain of uncharacterized transcription regulator ycjW which is a member of the LacI-GalR family repressors; Region: PBP1_ycjW_transcription_regulator_like; cd06294
696406004782	putative dimerization interface [polypeptide binding]; other site
696406004783	putative ligand binding site [chemical binding]; other site
696406004784	Predicted ATPase [General function prediction only]; Region: COG3106
696406004785	hypothetical protein; Provisional; Region: PRK05415
696406004786	TIGR01620 family protein; Region: hyp_HI0043
696406004787	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
696406004788	N-terminal ACT domain of the TyrR protein; Region: ACT_TyrR; cd04877
696406004789	putative aromatic amino acid binding site; other site
696406004790	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406004791	Walker A motif; other site
696406004792	ATP binding site [chemical binding]; other site
696406004793	Walker B motif; other site
696406004794	arginine finger; other site
696406004795	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
696406004796	dimer interface [polypeptide binding]; other site
696406004797	catalytic triad [active]
696406004798	peroxidatic and resolving cysteines [active]
696406004799	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
696406004800	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
696406004801	active site
696406004802	Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866
696406004803	Peptidase M14-like domain of Escherichia coli Murein Peptide Amidase A and related proteins; Region: M14_MpaA_like; cd06904
696406004804	putative active site [active]
696406004805	Zn binding site [ion binding]; other site
696406004806	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
696406004807	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
696406004808	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
696406004809	Transcriptional regulator [Transcription]; Region: LysR; COG0583
696406004810	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406004811	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
696406004812	putative effector binding pocket; other site
696406004813	putative dimerization interface [polypeptide binding]; other site
696406004814	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
696406004815	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
696406004816	peptide binding site [polypeptide binding]; other site
696406004817	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
696406004818	Mechanosensitive ion channel; Region: MS_channel; pfam00924
696406004819	Protein of unknown function (DUF2534); Region: DUF2534; pfam10749
696406004820	universal stress protein UspE; Provisional; Region: PRK11175
696406004821	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
696406004822	Ligand Binding Site [chemical binding]; other site
696406004823	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
696406004824	Ligand Binding Site [chemical binding]; other site
696406004825	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
696406004826	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
696406004827	ligand binding site [chemical binding]; other site
696406004828	flexible hinge region; other site
696406004829	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
696406004830	putative switch regulator; other site
696406004831	non-specific DNA interactions [nucleotide binding]; other site
696406004832	DNA binding site [nucleotide binding]
696406004833	sequence specific DNA binding site [nucleotide binding]; other site
696406004834	putative cAMP binding site [chemical binding]; other site
696406004835	O-6-alkylguanine-DNA:cysteine-protein methyltransferase; Provisional; Region: PRK10286
696406004836	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
696406004837	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
696406004838	DNA binding site [nucleotide binding]
696406004839	active site
696406004840	integrase; Provisional; Region: PRK09692
696406004841	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
696406004842	active site
696406004843	Int/Topo IB signature motif; other site
696406004844	NinB protein; Region: NinB; pfam05772
696406004845	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
696406004846	replicative DNA helicase; Region: DnaB; TIGR00665
696406004847	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
696406004848	Walker A motif; other site
696406004849	ATP binding site [chemical binding]; other site
696406004850	Walker B motif; other site
696406004851	DNA binding loops [nucleotide binding]
696406004852	Phage regulatory protein Rha (Phage_pRha); Region: Phage_pRha; pfam09669
696406004853	Phage antirepressor protein KilAC domain; Region: ANT; pfam03374
696406004854	Helix-turn-helix domain; Region: HTH_36; pfam13730
696406004855	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
696406004856	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
696406004857	non-specific DNA binding site [nucleotide binding]; other site
696406004858	salt bridge; other site
696406004859	sequence-specific DNA binding site [nucleotide binding]; other site
696406004860	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
696406004861	Catalytic site [active]
696406004862	ERF superfamily; Region: ERF; pfam04404
696406004863	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
696406004864	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
696406004865	dimer interface [polypeptide binding]; other site
696406004866	ssDNA binding site [nucleotide binding]; other site
696406004867	tetramer (dimer of dimers) interface [polypeptide binding]; other site
696406004868	Protein of unknown function (DUF2856); Region: DUF2856; pfam11043
696406004869	signal recognition particle protein; Region: ffh; TIGR00959
696406004870	DNA translocase FtsK; Provisional; Region: PRK10263
696406004871	DNA N-6-adenine-methyltransferase (Dam); Region: Dam; cl05442
696406004872	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
696406004873	Endodeoxyribonuclease RusA; Region: RusA; cl01885
696406004874	Antitermination protein; Region: Antiterm; pfam03589
696406004875	DnaJ central domain; Region: DnaJ_CXXCXGXG; pfam00684
696406004876	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
696406004877	Zn binding sites [ion binding]; other site
696406004878	Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB [Transcription]; Region: SUA7; COG1405
696406004879	ASC-1 homology or ASCH domain, a small beta-barrel domain found in all three kingdoms of life. ASCH resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as an RNA-binding domain during coactivation; Region: ASCH; cl01020
696406004880	Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes; Region: FA58C; cl12042
696406004881	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
696406004882	catalytic residues [active]
696406004883	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
696406004884	hypothetical protein; Region: PHA00527
696406004885	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cl17393
696406004886	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5410
696406004887	Uncharacterized conserved protein [Function unknown]; Region: COG5323
696406004888	Protein of unknown function (DUF1073); Region: DUF1073; pfam06381
696406004889	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
696406004890	Phage major tail protein 2; Region: Phage_tail_2; pfam06199
696406004891	tape measure domain; Region: tape_meas_nterm; TIGR02675
696406004892	Phage antirepressor protein KilAC domain; Region: ANT; cl01462
696406004893	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
696406004894	MPN+ (JAMM) motif; other site
696406004895	Zinc-binding site [ion binding]; other site
696406004896	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
696406004897	NlpC/P60 family; Region: NLPC_P60; cl17555
696406004898	Bacteriophage lambda tail assembly protein I; Region: Lambda_tail_I; cl01945
696406004899	Phage-related protein, tail component [Function unknown]; Region: COG4733
696406004900	Putative phage tail protein; Region: Phage-tail_3; pfam13550
696406004901	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
696406004902	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
696406004903	Chaperone of endosialidase; Region: Peptidase_S74; pfam13884
696406004904	putative aminobenzoyl-glutamate transporter; Provisional; Region: abgT; PRK11339
696406004905	p-Aminobenzoyl-glutamate transporter family; Region: ydaH; TIGR00819
696406004906	M20 Peptidase Aminoacylase 1-like protein 2 aminobenzoyl-glutamate utilization protein B subfamily; Region: M20_Acy1L2_AbgB; cd05673
696406004907	amidohydrolase; Region: amidohydrolases; TIGR01891
696406004908	putative metal binding site [ion binding]; other site
696406004909	M20 Peptidases Aminoacyclase-1 indole-3-acetic-L-aspartic acid hydrolase from bacteria and archaea; Region: M20_Acy1_IAAspH_bact; cd05665
696406004910	amidohydrolase; Region: amidohydrolases; TIGR01891
696406004911	putative metal binding site [ion binding]; other site
696406004912	dimer interface [polypeptide binding]; other site
696406004913	putative DNA-binding transcriptional regulator; Provisional; Region: PRK09791
696406004914	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406004915	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
696406004916	putative substrate binding pocket [chemical binding]; other site
696406004917	putative dimerization interface [polypeptide binding]; other site
696406004918	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
696406004919	Smr domain; Region: Smr; pfam01713
696406004920	PAS domain S-box; Region: sensory_box; TIGR00229
696406004921	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
696406004922	putative active site [active]
696406004923	heme pocket [chemical binding]; other site
696406004924	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
696406004925	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
696406004926	metal binding site [ion binding]; metal-binding site
696406004927	active site
696406004928	I-site; other site
696406004929	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
696406004930	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
696406004931	Cl binding site [ion binding]; other site
696406004932	oligomer interface [polypeptide binding]; other site
696406004933	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
696406004934	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
696406004935	ATP binding site [chemical binding]; other site
696406004936	Mg++ binding site [ion binding]; other site
696406004937	motif III; other site
696406004938	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
696406004939	nucleotide binding region [chemical binding]; other site
696406004940	ATP-binding site [chemical binding]; other site
696406004941	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
696406004942	putative RNA binding site [nucleotide binding]; other site
696406004943	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
696406004944	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
696406004945	Ligand Binding Site [chemical binding]; other site
696406004946	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
696406004947	Ligand Binding Site [chemical binding]; other site
696406004948	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
696406004949	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
696406004950	trimer interface [polypeptide binding]; other site
696406004951	eyelet of channel; other site
696406004952	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
696406004953	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
696406004954	dimer interface [polypeptide binding]; other site
696406004955	PYR/PP interface [polypeptide binding]; other site
696406004956	TPP binding site [chemical binding]; other site
696406004957	substrate binding site [chemical binding]; other site
696406004958	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
696406004959	Domain of unknown function; Region: EKR; smart00890
696406004960	4Fe-4S binding domain; Region: Fer4_6; pfam12837
696406004961	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
696406004962	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
696406004963	TPP-binding site [chemical binding]; other site
696406004964	dimer interface [polypeptide binding]; other site
696406004965	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
696406004966	Domain of unknown function (DUF333); Region: DUF333; pfam03891
696406004967	heat-inducible protein; Provisional; Region: PRK10449
696406004968	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
696406004969	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
696406004970	putative ligand binding site [chemical binding]; other site
696406004971	putative NAD binding site [chemical binding]; other site
696406004972	catalytic site [active]
696406004973	hypothetical protein; Provisional; Region: PRK10695
696406004974	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
696406004975	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3784
696406004976	DNA-binding transcriptional activator FeaR; Provisional; Region: PRK09685
696406004977	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406004978	Escherichia coli NAD+-dependent phenylacetaldehyde dehydrogenase PadA-like; Region: ALDH_PADH_NahF; cd07113
696406004979	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
696406004980	NAD(P) binding site [chemical binding]; other site
696406004981	catalytic residues [active]
696406004982	tyramine oxidase; Provisional; Region: tynA; PRK14696
696406004983	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
696406004984	Copper amine oxidase, N2 domain; Region: Cu_amine_oxidN2; pfam02727
696406004985	Copper amine oxidase, N3 domain; Region: Cu_amine_oxidN3; pfam02728
696406004986	Copper amine oxidase, enzyme domain; Region: Cu_amine_oxid; pfam01179
696406004987	bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; Provisional; Region: PRK11563
696406004988	N-terminal domain of the monoamine oxidase C dehydratase; Region: ALDH_MaoC-N; cd07128
696406004989	substrate binding site [chemical binding]; other site
696406004990	dimer interface [polypeptide binding]; other site
696406004991	NADP binding site [chemical binding]; other site
696406004992	catalytic residues [active]
696406004993	MaoC_C  The C-terminal hot dog fold of the MaoC (monoamine oxidase C) dehydratase regulatory protein. Orthologs of MaoC include PaaZ [Escherichia coli] and PaaN [Pseudomonas putida], which are putative ring-opening enzymes involved in phenylacetic acid...; Region: MaoC_C; cd03452
696406004994	substrate binding site [chemical binding]; other site
696406004995	phenylacetate-CoA oxygenase subunit PaaA; Provisional; Region: paaA; PRK13778
696406004996	phenylacetate-CoA oxygenase, PaaG subunit; Region: PA_CoA_Oxy1; TIGR02156
696406004997	phenylacetate-CoA oxygenase subunit PaaB; Provisional; Region: paaB; PRK13781
696406004998	phenylacetate-CoA oxygenase, PaaI subunit; Region: PA_CoA_Oxy3; TIGR02158
696406004999	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
696406005000	phenylacetate-CoA oxygenase, PaaJ subunit; Region: PA_CoA_Oxy4; TIGR02159
696406005001	phenylacetate-CoA oxygenase/reductase, PaaK subunit; Region: PA_CoA_Oxy5; TIGR02160
696406005002	NAD(P) binding domain of ferredoxin reductase like phenylacetic acid (PA) degradation oxidoreductase. PA oxidoreductases of E. coli hydroxylate PA-CoA in the second step of PA degradation. Members of this group typically fuse a ferredoxin reductase-like...; Region: PA_degradation_oxidoreductase_like; cd06214
696406005003	FAD binding pocket [chemical binding]; other site
696406005004	FAD binding motif [chemical binding]; other site
696406005005	phosphate binding motif [ion binding]; other site
696406005006	beta-alpha-beta structure motif; other site
696406005007	NAD(p) ribose binding residues [chemical binding]; other site
696406005008	NAD binding pocket [chemical binding]; other site
696406005009	NAD(P)-pyrophosphate-nicotinamide binding residues [chemical binding]; other site
696406005010	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
696406005011	catalytic loop [active]
696406005012	iron binding site [ion binding]; other site
696406005013	enoyl-CoA hydratase-isomerase; Provisional; Region: PRK09674
696406005014	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
696406005015	substrate binding site [chemical binding]; other site
696406005016	oxyanion hole (OAH) forming residues; other site
696406005017	trimer interface [polypeptide binding]; other site
696406005018	enoyl-CoA hydratase; Provisional; Region: PRK08140
696406005019	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
696406005020	substrate binding site [chemical binding]; other site
696406005021	oxyanion hole (OAH) forming residues; other site
696406005022	trimer interface [polypeptide binding]; other site
696406005023	3-hydroxyacyl-CoA dehydrogenase PaaC; Region: PaaC-3OHAcCoADH; TIGR02279
696406005024	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
696406005025	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
696406005026	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
696406005027	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
696406005028	CoenzymeA binding site [chemical binding]; other site
696406005029	subunit interaction site [polypeptide binding]; other site
696406005030	PHB binding site; other site
696406005031	beta-ketoadipyl CoA thiolase; Validated; Region: PRK09050
696406005032	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
696406005033	dimer interface [polypeptide binding]; other site
696406005034	active site
696406005035	Phenylacetate-CoA ligase (also known as PaaK); Region: PaaK; cd05913
696406005036	phenylacetate-CoA ligase; Region: PA_CoA_ligase; TIGR02155
696406005037	active site
696406005038	AMP binding site [chemical binding]; other site
696406005039	homodimer interface [polypeptide binding]; other site
696406005040	acyl-activating enzyme (AAE) consensus motif; other site
696406005041	CoA binding site [chemical binding]; other site
696406005042	PaaX-like protein; Region: PaaX; pfam07848
696406005043	phenylacetic acid degradation operon negative regulatory protein PaaX; Region: PaaX_trns_reg; TIGR02277
696406005044	PaaX-like protein C-terminal domain; Region: PaaX_C; pfam08223
696406005045	phenylacetic acid degradation protein PaaY; Region: PaaY; TIGR02287
696406005046	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
696406005047	putative trimer interface [polypeptide binding]; other site
696406005048	putative metal binding site [ion binding]; other site
696406005049	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
696406005050	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
696406005051	active site
696406005052	catalytic tetrad [active]
696406005053	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
696406005054	Protein of unknown function (DUF2773); Region: DUF2773; pfam10971
696406005055	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
696406005056	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406005057	S-adenosylmethionine binding site [chemical binding]; other site
696406005058	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
696406005059	PAP2_like proteins, Aur1_like subfamily. Yeast Aur1p or Ipc1p is necessary for the addition of inositol phosphate to ceramide, an essential step in yeast sphingolipid synthesis, and is the target of several antifungal compounds such as aureobasidin; Region: PAP2_Aur1_like; cd03386
696406005060	active site
696406005061	Dual specificity phosphatase, catalytic domain; Region: DSPc; smart00195
696406005062	active site
696406005063	catalytic residues [active]
696406005064	azoreductase; Reviewed; Region: PRK00170
696406005065	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
696406005066	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
696406005067	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
696406005068	ATP binding site [chemical binding]; other site
696406005069	putative Mg++ binding site [ion binding]; other site
696406005070	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
696406005071	nucleotide binding region [chemical binding]; other site
696406005072	ATP-binding site [chemical binding]; other site
696406005073	Helicase associated domain (HA2); Region: HA2; pfam04408
696406005074	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
696406005075	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
696406005076	Uncharacterized conserved protein [Function unknown]; Region: COG1434
696406005077	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
696406005078	putative active site [active]
696406005079	Escherichia coli lactaldehyde dehydrogenase AldA-like; Region: ALDH_LactADH-AldA; cd07088
696406005080	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
696406005081	NAD binding site [chemical binding]; other site
696406005082	catalytic residues [active]
696406005083	substrate binding site [chemical binding]; other site
696406005084	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
696406005085	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
696406005086	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
696406005087	cytochrome b561; Provisional; Region: PRK11513
696406005088	hypothetical protein; Provisional; Region: PRK10040
696406005089	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
696406005090	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
696406005091	dimer interface [polypeptide binding]; other site
696406005092	ligand binding site [chemical binding]; other site
696406005093	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
696406005094	dimerization interface [polypeptide binding]; other site
696406005095	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
696406005096	dimer interface [polypeptide binding]; other site
696406005097	putative CheW interface [polypeptide binding]; other site
696406005098	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
696406005099	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406005100	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
696406005101	dimerization interface [polypeptide binding]; other site
696406005102	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
696406005103	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
696406005104	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
696406005105	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
696406005106	hypothetical protein; Provisional; Region: PRK11415
696406005107	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
696406005108	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
696406005109	Coenzyme A binding pocket [chemical binding]; other site
696406005110	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
696406005111	putative trimer interface [polypeptide binding]; other site
696406005112	putative CoA binding site [chemical binding]; other site
696406005113	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cd00208
696406005114	putative trimer interface [polypeptide binding]; other site
696406005115	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
696406005116	putative CoA binding site [chemical binding]; other site
696406005117	putative trimer interface [polypeptide binding]; other site
696406005118	putative CoA binding site [chemical binding]; other site
696406005119	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
696406005120	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
696406005121	gating phenylalanine in ion channel; other site
696406005122	tellurite resistance protein TehB; Provisional; Region: PRK11207
696406005123	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406005124	S-adenosylmethionine binding site [chemical binding]; other site
696406005125	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
696406005126	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
696406005127	Probable transposase; Region: OrfB_IS605; pfam01385
696406005128	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
696406005129	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
696406005130	Uncharacterized protein involved in benzoate metabolism [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BenE; COG3135
696406005131	benzoate transporter; Region: benE; TIGR00843
696406005132	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
696406005133	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
696406005134	non-specific DNA binding site [nucleotide binding]; other site
696406005135	salt bridge; other site
696406005136	sequence-specific DNA binding site [nucleotide binding]; other site
696406005137	Cupin domain; Region: Cupin_2; pfam07883
696406005138	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
696406005139	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
696406005140	Peptidase family U32; Region: Peptidase_U32; pfam01136
696406005141	Collagenase; Region: DUF3656; pfam12392
696406005142	Protein of unknown function (DUF2554); Region: DUF2554; pfam10829
696406005143	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: COG1598
696406005144	Helix-turn-helix; Region: HTH_3; pfam01381
696406005145	sequence-specific DNA binding site [nucleotide binding]; other site
696406005146	salt bridge; other site
696406005147	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
696406005148	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
696406005149	DNA-binding site [nucleotide binding]; DNA binding site
696406005150	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
696406005151	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406005152	homodimer interface [polypeptide binding]; other site
696406005153	catalytic residue [active]
696406005154	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
696406005155	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
696406005156	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
696406005157	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
696406005158	Walker A/P-loop; other site
696406005159	ATP binding site [chemical binding]; other site
696406005160	Q-loop/lid; other site
696406005161	ABC transporter signature motif; other site
696406005162	Walker B; other site
696406005163	D-loop; other site
696406005164	H-loop/switch region; other site
696406005165	TOBE domain; Region: TOBE_2; pfam08402
696406005166	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406005167	dimer interface [polypeptide binding]; other site
696406005168	conserved gate region; other site
696406005169	putative PBP binding loops; other site
696406005170	ABC-ATPase subunit interface; other site
696406005171	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
696406005172	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406005173	ABC-ATPase subunit interface; other site
696406005174	gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK13473
696406005175	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
696406005176	tetrameric interface [polypeptide binding]; other site
696406005177	NAD binding site [chemical binding]; other site
696406005178	catalytic residues [active]
696406005179	substrate binding site [chemical binding]; other site
696406005180	Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and...; Region: LbH_XAT; cd03349
696406005181	trimer interface [polypeptide binding]; other site
696406005182	active site
696406005183	substrate binding site [chemical binding]; other site
696406005184	CoA binding site [chemical binding]; other site
696406005185	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
696406005186	Protein of unknown function (DUF2526); Region: DUF2526; pfam10735
696406005187	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
696406005188	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
696406005189	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
696406005190	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
696406005191	Prostaglandin dehydrogenases; Region: PGDH; cd05288
696406005192	NAD(P) binding site [chemical binding]; other site
696406005193	substrate binding site [chemical binding]; other site
696406005194	dimer interface [polypeptide binding]; other site
696406005195	colanic acid/biofilm transcriptional regulator; Provisional; Region: PRK11414
696406005196	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
696406005197	DNA-binding site [nucleotide binding]; DNA binding site
696406005198	FCD domain; Region: FCD; pfam07729
696406005199	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
696406005200	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
696406005201	N-terminal plug; other site
696406005202	ligand-binding site [chemical binding]; other site
696406005203	PQQ-like domain; Region: PQQ_2; pfam13360
696406005204	L-asparagine permease; Provisional; Region: PRK15049
696406005205	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
696406005206	C-terminal domain interface [polypeptide binding]; other site
696406005207	GSH binding site (G-site) [chemical binding]; other site
696406005208	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
696406005209	dimer interface [polypeptide binding]; other site
696406005210	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
696406005211	dimer interface [polypeptide binding]; other site
696406005212	N-terminal domain interface [polypeptide binding]; other site
696406005213	substrate binding pocket (H-site) [chemical binding]; other site
696406005214	type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361
696406005215	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
696406005216	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
696406005217	Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296
696406005218	PAAR motif; Region: PAAR_motif; cl15808
696406005219	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
696406005220	RHS Repeat; Region: RHS_repeat; pfam05593
696406005221	RHS Repeat; Region: RHS_repeat; pfam05593
696406005222	RHS Repeat; Region: RHS_repeat; pfam05593
696406005223	RHS Repeat; Region: RHS_repeat; pfam05593
696406005224	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
696406005225	RHS Repeat; Region: RHS_repeat; pfam05593
696406005226	RHS Repeat; Region: RHS_repeat; pfam05593
696406005227	RHS protein; Region: RHS; pfam03527
696406005228	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
696406005229	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
696406005230	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
696406005231	Transposase [DNA replication, recombination, and repair]; Region: COG5433
696406005232	Transposase [DNA replication, recombination, and repair]; Region: COG5433
696406005233	4-oxalocrotonate tautomerase; Provisional; Region: PRK01271
696406005234	active site 1 [active]
696406005235	dimer interface [polypeptide binding]; other site
696406005236	hexamer interface [polypeptide binding]; other site
696406005237	active site 2 [active]
696406005238	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
696406005239	N-hydroxyarylamine O-acetyltransferase; Provisional; Region: PRK15047
696406005240	hypothetical protein; Provisional; Region: PRK10281
696406005241	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
696406005242	nitrate reductase 2 subunit delta; Provisional; Region: PRK15054
696406005243	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
696406005244	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
696406005245	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
696406005246	[4Fe-4S] binding site [ion binding]; other site
696406005247	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
696406005248	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
696406005249	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
696406005250	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
696406005251	molybdopterin cofactor binding site; other site
696406005252	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
696406005253	Leucine-rich repeat (LRR) protein [Function unknown]; Region: COG4886
696406005254	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
696406005255	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
696406005256	aromatic amino acid exporter; Provisional; Region: PRK11689
696406005257	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
696406005258	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
696406005259	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
696406005260	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
696406005261	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
696406005262	molybdopterin cofactor binding site; other site
696406005263	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
696406005264	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
696406005265	formate dehydrogenase-N subunit gamma; Provisional; Region: PRK10179
696406005266	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
696406005267	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
696406005268	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
696406005269	non-specific DNA binding site [nucleotide binding]; other site
696406005270	salt bridge; other site
696406005271	sequence-specific DNA binding site [nucleotide binding]; other site
696406005272	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
696406005273	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
696406005274	NAD binding site [chemical binding]; other site
696406005275	substrate binding site [chemical binding]; other site
696406005276	catalytic Zn binding site [ion binding]; other site
696406005277	tetramer interface [polypeptide binding]; other site
696406005278	structural Zn binding site [ion binding]; other site
696406005279	malate dehydrogenase; Provisional; Region: PRK13529
696406005280	Malic enzyme, N-terminal domain; Region: malic; pfam00390
696406005281	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
696406005282	NAD(P) binding site [chemical binding]; other site
696406005283	30S ribosomal subunit S22; Reviewed; Region: rpsV; PRK10057
696406005284	Putative biofilm-dependent modulation protein; Region: BDM; cl11581
696406005285	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
696406005286	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
696406005287	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
696406005288	Walker A/P-loop; other site
696406005289	ATP binding site [chemical binding]; other site
696406005290	Q-loop/lid; other site
696406005291	ABC transporter signature motif; other site
696406005292	Walker B; other site
696406005293	D-loop; other site
696406005294	H-loop/switch region; other site
696406005295	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
696406005296	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
696406005297	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
696406005298	Walker A/P-loop; other site
696406005299	ATP binding site [chemical binding]; other site
696406005300	Q-loop/lid; other site
696406005301	ABC transporter signature motif; other site
696406005302	Walker B; other site
696406005303	D-loop; other site
696406005304	H-loop/switch region; other site
696406005305	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
696406005306	D-ala-D-ala transporter subunit; Provisional; Region: PRK09881
696406005307	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
696406005308	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406005309	dimer interface [polypeptide binding]; other site
696406005310	conserved gate region; other site
696406005311	putative PBP binding loops; other site
696406005312	ABC-ATPase subunit interface; other site
696406005313	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
696406005314	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406005315	dimer interface [polypeptide binding]; other site
696406005316	conserved gate region; other site
696406005317	putative PBP binding loops; other site
696406005318	ABC-ATPase subunit interface; other site
696406005319	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512
696406005320	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
696406005321	D-alanyl-D-alanine dipeptidase; Provisional; Region: PRK10178
696406005322	cyclic-di-GMP phosphodiesterase; Provisional; Region: PRK11359
696406005323	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
696406005324	putative active site [active]
696406005325	heme pocket [chemical binding]; other site
696406005326	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
696406005327	putative active site [active]
696406005328	heme pocket [chemical binding]; other site
696406005329	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
696406005330	metal binding site [ion binding]; metal-binding site
696406005331	active site
696406005332	I-site; other site
696406005333	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
696406005334	Globin domain present in Globin-Coupled-Sensors (GCS). These domains detect changes in intracellular concentrations of oxygen, carbon monoxyde, or nitrous oxide,  which result in aerotaxis and/or gene regulation. One subgroup, the HemATs, are aerotactic...; Region: sensor_globin; cd01068
696406005335	heme-binding site [chemical binding]; other site
696406005336	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
696406005337	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
696406005338	metal binding site [ion binding]; metal-binding site
696406005339	active site
696406005340	I-site; other site
696406005341	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
696406005342	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1649
696406005343	glutamate:gamma-aminobutyrate antiporter; Region: 2A0307_GadC; TIGR00910
696406005344	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
696406005345	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406005346	catalytic residue [active]
696406005347	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
696406005348	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
696406005349	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
696406005350	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
696406005351	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
696406005352	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
696406005353	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
696406005354	ABC transporter transmembrane region 2; Region: ABC_membrane_2; cl00549
696406005355	ATP-binding cassette domain of peroxisomal transporter, subfamily D; Region: ABCD_peroxisomal_ALDP; cd03223
696406005356	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
696406005357	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
696406005358	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
696406005359	FeS/SAM binding site; other site
696406005360	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
696406005361	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
696406005362	Sulfatase; Region: Sulfatase; pfam00884
696406005363	transcriptional regulator YdeO; Provisional; Region: PRK09940
696406005364	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406005365	putative oxidoreductase; Provisional; Region: PRK09939
696406005366	The MopB_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins; Region: MopB_ydeP; cd02767
696406005367	putative molybdopterin cofactor binding site [chemical binding]; other site
696406005368	The MopB_CT_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. This CD is of the conserved molybdopterin_binding C-terminal (MopB_CT) region...; Region: MopB_CT_ydeP; cd02787
696406005369	putative molybdopterin cofactor binding site; other site
696406005370	Mannose binding  domain of FimH and related proteins; Region: FimH_man-bind; cd10466
696406005371	mannosyl binding site [chemical binding]; other site
696406005372	Fimbrial protein; Region: Fimbrial; pfam00419
696406005373	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
696406005374	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
696406005375	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
696406005376	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
696406005377	PapC C-terminal domain; Region: PapC_C; pfam13953
696406005378	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
696406005379	AAA domain; Region: AAA_21; pfam13304
696406005380	AAA ATPase domain; Region: AAA_16; pfam13191
696406005381	Walker A motif; other site
696406005382	ATP binding site [chemical binding]; other site
696406005383	Walker B motif; other site
696406005384	Divergent AAA domain; Region: AAA_4; pfam04326
696406005385	SEC-C motif; Region: SEC-C; pfam02810
696406005386	AAA domain; Region: AAA_23; pfam13476
696406005387	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
696406005388	Walker A/P-loop; other site
696406005389	ATP binding site [chemical binding]; other site
696406005390	AAA domain; Region: AAA_21; pfam13304
696406005391	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
696406005392	active site
696406005393	metal binding site [ion binding]; metal-binding site
696406005394	UvrD/REP helicase N-terminal domain; Region: UvrD-helicase; pfam00580
696406005395	Transposase; Region: HTH_Tnp_1; cl17663
696406005396	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
696406005397	HTH-like domain; Region: HTH_21; pfam13276
696406005398	Integrase core domain; Region: rve; pfam00665
696406005399	DDE domain; Region: DDE_Tnp_IS240; pfam13610
696406005400	Integrase core domain; Region: rve_2; pfam13333
696406005401	HipA N-terminal domain; Region: Couple_hipA; pfam13657
696406005402	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
696406005403	HipA-like N-terminal domain; Region: HipA_N; pfam07805
696406005404	HipA-like C-terminal domain; Region: HipA_C; pfam07804
696406005405	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
696406005406	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
696406005407	non-specific DNA binding site [nucleotide binding]; other site
696406005408	salt bridge; other site
696406005409	sequence-specific DNA binding site [nucleotide binding]; other site
696406005410	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
696406005411	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
696406005412	Autotransporter beta-domain; Region: Autotransporter; pfam03797
696406005413	putative lipoprotein; Provisional; Region: PRK09707
696406005414	autoinducer-2 (AI-2) kinase; Provisional; Region: PRK10939
696406005415	Autoinducer-2 kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_AI-2K; cd07775
696406005416	putative N- and C-terminal domain interface [polypeptide binding]; other site
696406005417	putative active site [active]
696406005418	putative MgATP binding site [chemical binding]; other site
696406005419	catalytic site [active]
696406005420	metal binding site [ion binding]; metal-binding site
696406005421	putative carbohydrate binding site [chemical binding]; other site
696406005422	transcriptional regulator LsrR; Provisional; Region: PRK15418
696406005423	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
696406005424	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
696406005425	autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional; Region: PRK15439
696406005426	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
696406005427	Walker A/P-loop; other site
696406005428	ATP binding site [chemical binding]; other site
696406005429	Q-loop/lid; other site
696406005430	ABC transporter signature motif; other site
696406005431	Walker B; other site
696406005432	D-loop; other site
696406005433	H-loop/switch region; other site
696406005434	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
696406005435	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
696406005436	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
696406005437	TM-ABC transporter signature motif; other site
696406005438	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
696406005439	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
696406005440	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
696406005441	TM-ABC transporter signature motif; other site
696406005442	autoinducer 2-binding protein lsrB; Provisional; Region: PRK15408
696406005443	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
696406005444	ligand binding site [chemical binding]; other site
696406005445	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
696406005446	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
696406005447	putative active site; other site
696406005448	catalytic residue [active]
696406005449	autoinducer-2 (AI-2) modifying protein LsrG; Provisional; Region: PRK10486
696406005450	Trans-aconitate methyltransferase [General function prediction only]; Region: Tam; COG4106
696406005451	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406005452	S-adenosylmethionine binding site [chemical binding]; other site
696406005453	Predicted membrane protein [Function unknown]; Region: COG3781
696406005454	altronate oxidoreductase; Provisional; Region: PRK03643
696406005455	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
696406005456	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
696406005457	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
696406005458	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
696406005459	metal binding site [ion binding]; metal-binding site
696406005460	active site
696406005461	I-site; other site
696406005462	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
696406005463	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
696406005464	glutaminase; Provisional; Region: PRK00971
696406005465	putative succinate semialdehyde dehydrogenase; Provisional; Region: PRK13968
696406005466	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
696406005467	NAD(P) binding site [chemical binding]; other site
696406005468	catalytic residues [active]
696406005469	Transcriptional regulator [Transcription]; Region: LysR; COG0583
696406005470	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406005471	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
696406005472	putative dimerization interface [polypeptide binding]; other site
696406005473	putative arabinose transporter; Provisional; Region: PRK03545
696406005474	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406005475	putative substrate translocation pore; other site
696406005476	inner membrane protein; Provisional; Region: PRK10995
696406005477	DNA-binding transcriptional repressor MarR; Provisional; Region: PRK11512
696406005478	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
696406005479	DNA-binding transcriptional activator MarA; Provisional; Region: PRK11511
696406005480	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406005481	hypothetical protein; Provisional; Region: PRK10106
696406005482	6-phospho-beta-glucosidase; Reviewed; Region: celA; PRK09589
696406005483	beta-galactosidase; Region: BGL; TIGR03356
696406005484	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
696406005485	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
696406005486	trimer interface; other site
696406005487	sugar binding site [chemical binding]; other site
696406005488	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
696406005489	active site
696406005490	methionine cluster; other site
696406005491	phosphorylation site [posttranslational modification]
696406005492	metal binding site [ion binding]; metal-binding site
696406005493	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
696406005494	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
696406005495	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
696406005496	active site
696406005497	P-loop; other site
696406005498	phosphorylation site [posttranslational modification]
696406005499	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
696406005500	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
696406005501	DNA-binding site [nucleotide binding]; DNA binding site
696406005502	UTRA domain; Region: UTRA; pfam07702
696406005503	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
696406005504	EamA-like transporter family; Region: EamA; pfam00892
696406005505	EamA-like transporter family; Region: EamA; pfam00892
696406005506	putative transporter; Provisional; Region: PRK10054
696406005507	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406005508	putative substrate translocation pore; other site
696406005509	diguanylate cyclase; Provisional; Region: PRK09894
696406005510	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
696406005511	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
696406005512	metal binding site [ion binding]; metal-binding site
696406005513	active site
696406005514	I-site; other site
696406005515	hypothetical protein; Provisional; Region: PRK10053
696406005516	hypothetical protein; Validated; Region: PRK03657
696406005517	dipeptidyl carboxypeptidase II; Provisional; Region: PRK10280
696406005518	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
696406005519	active site
696406005520	Zn binding site [ion binding]; other site
696406005521	malonic semialdehyde reductase; Provisional; Region: PRK10538
696406005522	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
696406005523	putative NAD(P) binding site [chemical binding]; other site
696406005524	homodimer interface [polypeptide binding]; other site
696406005525	homotetramer interface [polypeptide binding]; other site
696406005526	active site
696406005527	Transcriptional regulators [Transcription]; Region: GntR; COG1802
696406005528	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
696406005529	DNA-binding site [nucleotide binding]; DNA binding site
696406005530	FCD domain; Region: FCD; pfam07729
696406005531	putative selenium-binding protein YdfZ; Region: YdfZ_fam; TIGR03318
696406005532	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
696406005533	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
696406005534	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
696406005535	metabolite-proton symporter; Region: 2A0106; TIGR00883
696406005536	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406005537	putative substrate translocation pore; other site
696406005538	multiple promoter invertase; Provisional; Region: mpi; PRK13413
696406005539	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
696406005540	catalytic residues [active]
696406005541	catalytic nucleophile [active]
696406005542	Presynaptic Site I dimer interface [polypeptide binding]; other site
696406005543	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
696406005544	Synaptic Flat tetramer interface [polypeptide binding]; other site
696406005545	Synaptic Site I dimer interface [polypeptide binding]; other site
696406005546	DNA binding site [nucleotide binding]
696406005547	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
696406005548	DNA-binding interface [nucleotide binding]; DNA binding site
696406005549	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
696406005550	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
696406005551	Phage Tail Collar Domain; Region: Collar; pfam07484
696406005552	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
696406005553	Phage-related protein, tail component [Function unknown]; Region: COG4733
696406005554	Putative phage tail protein; Region: Phage-tail_3; pfam13550
696406005555	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
696406005556	Fibronectin type III protein; Region: DUF3672; pfam12421
696406005557	Phage-related protein, tail component [Function unknown]; Region: COG4723
696406005558	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
696406005559	MPN+ (JAMM) motif; other site
696406005560	Zinc-binding site [ion binding]; other site
696406005561	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
696406005562	NlpC/P60 family; Region: NLPC_P60; cl17555
696406005563	Phage-related protein [Function unknown]; Region: gp18; COG4672
696406005564	Phage-related protein [Function unknown]; Region: COG4718
696406005565	Phage-related minor tail protein [Function unknown]; Region: COG5281
696406005566	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
696406005567	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
696406005568	Minor tail protein T; Region: Phage_tail_T; pfam06223
696406005569	phage minor tail protein G; Region: phage_lambda_G; TIGR01674
696406005570	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
696406005571	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
696406005572	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
696406005573	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
696406005574	Phage Head-Tail Attachment; Region: Phage_attach; pfam05354
696406005575	DNA packaging protein FI; Region: Packaging_FI; pfam14000
696406005576	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
696406005577	Bacteriophage lambda head decoration protein D; Region: HDPD; pfam02924
696406005578	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
696406005579	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
696406005580	tandem repeat interface [polypeptide binding]; other site
696406005581	oligomer interface [polypeptide binding]; other site
696406005582	active site residues [active]
696406005583	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
696406005584	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
696406005585	gpW; Region: gpW; pfam02831
696406005586	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
696406005587	Phage DNA packaging protein Nu1; Region: Phage_Nu1; pfam07471
696406005588	Domain of unknown function (DUF3950); Region: DUF3950; pfam13132
696406005589	GnsA/GnsB family; Region: GnsAB; pfam08178
696406005590	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
696406005591	DNA-binding site [nucleotide binding]; DNA binding site
696406005592	RNA-binding motif; other site
696406005593	Protein of unknown function (DUF2514); Region: DUF2514; pfam10721
696406005594	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
696406005595	catalytic residues [active]
696406005596	Protein of unknown function (DUF1327); Region: DUF1327; pfam07041
696406005597	Lysis protein S; Region: Lysis_S; pfam04971
696406005598	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
696406005599	DNA-binding site [nucleotide binding]; DNA binding site
696406005600	RNA-binding motif; other site
696406005601	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
696406005602	DNA-binding site [nucleotide binding]; DNA binding site
696406005603	RNA-binding motif; other site
696406005604	Antitermination protein; Region: Antiterm; pfam03589
696406005605	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
696406005606	DnaJ central domain; Region: DnaJ_CXXCXGXG; pfam00684
696406005607	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
696406005608	Protein of unknown function (DUF968); Region: DUF968; pfam06147
696406005609	bifunctional antitoxin/transcriptional repressor RelB; Provisional; Region: PRK11235
696406005610	Homeodomain-like domain; Region: HTH_23; pfam13384
696406005611	Winged helix-turn helix; Region: HTH_29; pfam13551
696406005612	Homeodomain-like domain; Region: HTH_32; pfam13565
696406005613	Integrase core domain; Region: rve; pfam00665
696406005614	Integrase core domain; Region: rve_3; cl15866
696406005615	Methyltransferase domain; Region: Methyltransf_25; pfam13649
696406005616	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
696406005617	primosomal protein DnaI; Provisional; Region: PRK02854
696406005618	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
696406005619	DNA-binding transcriptional regulator DicC; Provisional; Region: PRK09744
696406005620	Protein of unknown function (DUF1391); Region: DUF1391; pfam07151
696406005621	DicB protein; Region: DicB; pfam05358
696406005622	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
696406005623	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
696406005624	Putative excisionase (DUF1233); Region: DUF1233; pfam06806
696406005625	Domain of unknown function (DUF3596); Region: DUF3596; pfam12167
696406005626	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
696406005627	phiCTX phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various phage and bacterial integrases, including those similar to phage integrases: Bordetella and...; Region: INT_phiCTX_C; cd01191
696406005628	Int/Topo IB signature motif; other site
696406005629	putative oxidoreductase; Provisional; Region: PRK10083
696406005630	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
696406005631	putative NAD(P) binding site [chemical binding]; other site
696406005632	catalytic Zn binding site [ion binding]; other site
696406005633	structural Zn binding site [ion binding]; other site
696406005634	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
696406005635	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
696406005636	putative active site pocket [active]
696406005637	putative metal binding site [ion binding]; other site
696406005638	hypothetical protein; Provisional; Region: PRK02237
696406005639	hypothetical protein; Provisional; Region: PRK13659
696406005640	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
696406005641	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
696406005642	Coenzyme A binding pocket [chemical binding]; other site
696406005643	Uncharacterized protein family (UPF0257); Region: UPF0257; pfam06788
696406005644	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
696406005645	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
696406005646	molybdopterin cofactor binding site; other site
696406005647	Protein of unknown function (DUF1682); Region: DUF1682; pfam07946
696406005648	KilA-N domain; Region: KilA-N; pfam04383
696406005649	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
696406005650	active site
696406005651	DNA binding site [nucleotide binding]
696406005652	Int/Topo IB signature motif; other site
696406005653	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
696406005654	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
696406005655	putative molybdopterin cofactor binding site; other site
696406005656	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
696406005657	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
696406005658	putative [Fe4-S4] binding site [ion binding]; other site
696406005659	putative molybdopterin cofactor binding site [chemical binding]; other site
696406005660	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
696406005661	putative molybdopterin cofactor binding site; other site
696406005662	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
696406005663	4Fe-4S binding domain; Region: Fer4; cl02805
696406005664	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
696406005665	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
696406005666	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
696406005667	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
696406005668	Cl- selectivity filter; other site
696406005669	Cl- binding residues [ion binding]; other site
696406005670	pore gating glutamate residue; other site
696406005671	dimer interface [polypeptide binding]; other site
696406005672	putative dithiobiotin synthetase; Provisional; Region: PRK12374
696406005673	AAA domain; Region: AAA_26; pfam13500
696406005674	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
696406005675	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
696406005676	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
696406005677	nucleotide binding site [chemical binding]; other site
696406005678	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
696406005679	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406005680	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
696406005681	dimerization interface [polypeptide binding]; other site
696406005682	substrate binding pocket [chemical binding]; other site
696406005683	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
696406005684	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406005685	putative substrate translocation pore; other site
696406005686	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
696406005687	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
696406005688	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
696406005689	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; PRK12287
696406005690	Domain of unknown function DUF20; Region: UPF0118; pfam01594
696406005691	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
696406005692	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
696406005693	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
696406005694	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
696406005695	ligand binding site [chemical binding]; other site
696406005696	homodimer interface [polypeptide binding]; other site
696406005697	NAD(P) binding site [chemical binding]; other site
696406005698	trimer interface B [polypeptide binding]; other site
696406005699	trimer interface A [polypeptide binding]; other site
696406005700	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
696406005701	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
696406005702	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
696406005703	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
696406005704	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
696406005705	Spore germination protein; Region: Spore_permease; cl17796
696406005706	dihydromonapterin reductase; Provisional; Region: PRK06483
696406005707	pteridine reductase (PR), classical (c) SDRs; Region: PR_SDR_c; cd05357
696406005708	NADP binding site [chemical binding]; other site
696406005709	substrate binding pocket [chemical binding]; other site
696406005710	active site
696406005711	GlpM protein; Region: GlpM; pfam06942
696406005712	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
696406005713	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406005714	active site
696406005715	phosphorylation site [posttranslational modification]
696406005716	intermolecular recognition site; other site
696406005717	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
696406005718	DNA binding site [nucleotide binding]
696406005719	sensor protein RstB; Provisional; Region: PRK10604
696406005720	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
696406005721	dimerization interface [polypeptide binding]; other site
696406005722	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
696406005723	dimer interface [polypeptide binding]; other site
696406005724	phosphorylation site [posttranslational modification]
696406005725	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406005726	ATP binding site [chemical binding]; other site
696406005727	Mg2+ binding site [ion binding]; other site
696406005728	G-X-G motif; other site
696406005729	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
696406005730	fumarate hydratase; Reviewed; Region: fumC; PRK00485
696406005731	Class II fumarases; Region: Fumarase_classII; cd01362
696406005732	active site
696406005733	tetramer interface [polypeptide binding]; other site
696406005734	fumarate hydratase; Provisional; Region: PRK15389
696406005735	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
696406005736	Fumarase C-terminus; Region: Fumerase_C; pfam05683
696406005737	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
696406005738	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
696406005739	mannose-6-phosphate isomerase, class I; Region: manA; TIGR00218
696406005740	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
696406005741	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
696406005742	putative outer membrane porin protein; Provisional; Region: PRK11379
696406005743	glucuronide transporter; Provisional; Region: PRK09848
696406005744	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
696406005745	beta-D-glucuronidase; Provisional; Region: PRK10150
696406005746	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
696406005747	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
696406005748	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
696406005749	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
696406005750	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
696406005751	7-alpha-hydroxysteroid dehydrogenase; Validated; Region: PRK06113
696406005752	7 alpha-hydroxysteroid dehydrogenase (7 alpha-HSDH), classical (c) SDRs; Region: 7_alpha_HSDH_SDR_c; cd05365
696406005753	NAD binding site [chemical binding]; other site
696406005754	substrate binding site [chemical binding]; other site
696406005755	homotetramer interface [polypeptide binding]; other site
696406005756	homodimer interface [polypeptide binding]; other site
696406005757	active site
696406005758	DNA-binding transcriptional repressor MalI; Provisional; Region: PRK10014
696406005759	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
696406005760	DNA binding site [nucleotide binding]
696406005761	domain linker motif; other site
696406005762	Ligand-binding domain of MalI, a transcription regulator of the maltose system of Escherichia coli and its close homologs from other bacteria; Region: PBP1_MalI_like; cd06289
696406005763	putative dimerization interface [polypeptide binding]; other site
696406005764	putative ligand binding site [chemical binding]; other site
696406005765	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
696406005766	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
696406005767	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
696406005768	active site turn [active]
696406005769	phosphorylation site [posttranslational modification]
696406005770	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
696406005771	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
696406005772	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406005773	homodimer interface [polypeptide binding]; other site
696406005774	catalytic residue [active]
696406005775	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
696406005776	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
696406005777	active site
696406005778	purine riboside binding site [chemical binding]; other site
696406005779	putative oxidoreductase; Provisional; Region: PRK11579
696406005780	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
696406005781	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
696406005782	oriC-binding nucleoid-associated protein; Provisional; Region: PRK10391
696406005783	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
696406005784	electron transport complex protein RsxA; Provisional; Region: PRK05151
696406005785	electron transport complex protein RnfB; Provisional; Region: PRK05113
696406005786	Putative Fe-S cluster; Region: FeS; pfam04060
696406005787	4Fe-4S binding domain; Region: Fer4; pfam00037
696406005788	Predicted NADH:ubiquinone oxidoreductase, subunit RnfC [Energy production and conversion]; Region: RnfC; COG4656
696406005789	SLBB domain; Region: SLBB; pfam10531
696406005790	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
696406005791	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
696406005792	electron transport complex protein RnfG; Validated; Region: PRK01908
696406005793	electron transport complex RsxE subunit; Provisional; Region: PRK12405
696406005794	endonuclease III; Provisional; Region: PRK10702
696406005795	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
696406005796	minor groove reading motif; other site
696406005797	helix-hairpin-helix signature motif; other site
696406005798	substrate binding pocket [chemical binding]; other site
696406005799	active site
696406005800	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
696406005801	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
696406005802	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406005803	putative substrate translocation pore; other site
696406005804	POT family; Region: PTR2; pfam00854
696406005805	glutathionine S-transferase; Provisional; Region: PRK10542
696406005806	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
696406005807	C-terminal domain interface [polypeptide binding]; other site
696406005808	GSH binding site (G-site) [chemical binding]; other site
696406005809	dimer interface [polypeptide binding]; other site
696406005810	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
696406005811	N-terminal domain interface [polypeptide binding]; other site
696406005812	dimer interface [polypeptide binding]; other site
696406005813	substrate binding pocket (H-site) [chemical binding]; other site
696406005814	pyridoxamine kinase; Validated; Region: PRK05756
696406005815	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
696406005816	dimer interface [polypeptide binding]; other site
696406005817	pyridoxal binding site [chemical binding]; other site
696406005818	ATP binding site [chemical binding]; other site
696406005819	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
696406005820	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
696406005821	active site
696406005822	HIGH motif; other site
696406005823	dimer interface [polypeptide binding]; other site
696406005824	KMSKS motif; other site
696406005825	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
696406005826	RNA binding surface [nucleotide binding]; other site
696406005827	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
696406005828	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
696406005829	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
696406005830	lysozyme inhibitor; Provisional; Region: PRK11372
696406005831	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
696406005832	Uncharacterized protein family (UPF0075); Region: UPF0075; pfam03702
696406005833	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
696406005834	transcriptional regulator SlyA; Provisional; Region: PRK03573
696406005835	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
696406005836	Protein of unknown function (DUF1656); Region: DUF1656; cl11658
696406005837	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
696406005838	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
696406005839	HlyD family secretion protein; Region: HlyD_3; pfam13437
696406005840	Fusaric acid resistance protein family; Region: FUSC; pfam04632
696406005841	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
696406005842	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
696406005843	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
696406005844	E-class dimer interface [polypeptide binding]; other site
696406005845	P-class dimer interface [polypeptide binding]; other site
696406005846	active site
696406005847	Cu2+ binding site [ion binding]; other site
696406005848	Zn2+ binding site [ion binding]; other site
696406005849	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
696406005850	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
696406005851	active site
696406005852	catalytic tetrad [active]
696406005853	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
696406005854	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
696406005855	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
696406005856	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
696406005857	FMN binding site [chemical binding]; other site
696406005858	active site
696406005859	substrate binding site [chemical binding]; other site
696406005860	catalytic residue [active]
696406005861	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
696406005862	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
696406005863	dimer interface [polypeptide binding]; other site
696406005864	active site
696406005865	metal binding site [ion binding]; metal-binding site
696406005866	glutathione binding site [chemical binding]; other site
696406005867	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
696406005868	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
696406005869	dimer interface [polypeptide binding]; other site
696406005870	catalytic site [active]
696406005871	putative active site [active]
696406005872	putative substrate binding site [chemical binding]; other site
696406005873	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
696406005874	putative ATP-dependent helicase Lhr; Provisional; Region: PRK09751
696406005875	ATP binding site [chemical binding]; other site
696406005876	putative Mg++ binding site [ion binding]; other site
696406005877	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
696406005878	nucleotide binding region [chemical binding]; other site
696406005879	ATP-binding site [chemical binding]; other site
696406005880	DEAD/H associated; Region: DEAD_assoc; pfam08494
696406005881	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
696406005882	putative GSH binding site [chemical binding]; other site
696406005883	catalytic residues [active]
696406005884	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
696406005885	NlpC/P60 family; Region: NLPC_P60; pfam00877
696406005886	superoxide dismutase; Provisional; Region: PRK10543
696406005887	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
696406005888	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
696406005889	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406005890	Major Facilitator Superfamily; Region: MFS_1; pfam07690
696406005891	putative substrate translocation pore; other site
696406005892	hypothetical protein; Provisional; Region: PRK14756
696406005893	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
696406005894	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
696406005895	DNA binding site [nucleotide binding]
696406005896	domain linker motif; other site
696406005897	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
696406005898	dimerization interface [polypeptide binding]; other site
696406005899	ligand binding site [chemical binding]; other site
696406005900	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
696406005901	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406005902	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
696406005903	dimerization interface [polypeptide binding]; other site
696406005904	putative transporter; Provisional; Region: PRK11043
696406005905	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406005906	putative substrate translocation pore; other site
696406005907	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
696406005908	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
696406005909	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406005910	S-adenosylmethionine binding site [chemical binding]; other site
696406005911	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
696406005912	Lumazine binding domain; Region: Lum_binding; pfam00677
696406005913	Lumazine binding domain; Region: Lum_binding; pfam00677
696406005914	multidrug efflux protein; Reviewed; Region: PRK01766
696406005915	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
696406005916	cation binding site [ion binding]; other site
696406005917	hypothetical protein; Provisional; Region: PRK09945
696406005918	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
696406005919	putative monooxygenase; Provisional; Region: PRK11118
696406005920	hypothetical protein; Provisional; Region: PRK09897
696406005921	FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454
696406005922	hypothetical protein; Provisional; Region: PRK09946
696406005923	thiosulfate reductase cytochrome B subunit; Provisional; Region: PRK15006
696406005924	Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion]; Region: COG4117
696406005925	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
696406005926	hypothetical protein; Provisional; Region: PRK09947
696406005927	putative oxidoreductase; Provisional; Region: PRK09849
696406005928	Aldehyde ferredoxin oxidoreductase, N-terminal domain; Region: AFOR_N; pfam02730
696406005929	Aldehyde ferredoxin oxidoreductase, domains 2 & 3; Region: AFOR_C; pfam01314
696406005930	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
696406005931	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
696406005932	hypothetical protein; Provisional; Region: PRK10292
696406005933	pyruvate kinase; Provisional; Region: PRK09206
696406005934	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
696406005935	domain interfaces; other site
696406005936	active site
696406005937	murein lipoprotein; Provisional; Region: PRK15396
696406005938	L,D-transpeptidase; Provisional; Region: PRK10190
696406005939	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
696406005940	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
696406005941	cysteine desufuration protein SufE; Provisional; Region: PRK09296
696406005942	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
696406005943	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
696406005944	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
696406005945	catalytic residue [active]
696406005946	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
696406005947	FeS assembly protein SufD; Region: sufD; TIGR01981
696406005948	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
696406005949	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
696406005950	Walker A/P-loop; other site
696406005951	ATP binding site [chemical binding]; other site
696406005952	Q-loop/lid; other site
696406005953	ABC transporter signature motif; other site
696406005954	Walker B; other site
696406005955	D-loop; other site
696406005956	H-loop/switch region; other site
696406005957	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
696406005958	putative ABC transporter; Region: ycf24; CHL00085
696406005959	iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504
696406005960	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
696406005961	CoenzymeA binding site [chemical binding]; other site
696406005962	subunit interaction site [polypeptide binding]; other site
696406005963	PHB binding site; other site
696406005964	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
696406005965	FAD binding domain; Region: FAD_binding_4; pfam01565
696406005966	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
696406005967	putative inner membrane protein; Provisional; Region: PRK10983
696406005968	Domain of unknown function DUF20; Region: UPF0118; pfam01594
696406005969	Domain of unknown function (DUF1870); Region: DUF1870; pfam08965
696406005970	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406005971	Major Facilitator Superfamily; Region: MFS_1; pfam07690
696406005972	putative substrate translocation pore; other site
696406005973	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406005974	putative substrate translocation pore; other site
696406005975	quinate/shikimate dehydrogenase; Reviewed; Region: PRK12749
696406005976	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
696406005977	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
696406005978	shikimate binding site; other site
696406005979	NAD(P) binding site [chemical binding]; other site
696406005980	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
696406005981	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
696406005982	active site
696406005983	catalytic residue [active]
696406005984	dimer interface [polypeptide binding]; other site
696406005985	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
696406005986	Coenzyme A transferase; Region: CoA_trans; smart00882
696406005987	Coenzyme A transferase; Region: CoA_trans; cl17247
696406005988	putative acyl-CoA dehydrogenase; Provisional; Region: PRK12341
696406005989	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
696406005990	active site
696406005991	Cupin domain; Region: Cupin_2; pfam07883
696406005992	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
696406005993	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
696406005994	Ligand binding site [chemical binding]; other site
696406005995	Electron transfer flavoprotein domain; Region: ETF; pfam01012
696406005996	electron transfer flavoprotein subunit YdiR; Provisional; Region: PRK11916
696406005997	Electron transfer flavoprotein domain; Region: ETF; smart00893
696406005998	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
696406005999	oxidoreductase; Provisional; Region: PRK10015
696406006000	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
696406006001	short chain acyl-CoA synthetase; Reviewed; Region: PRK06087
696406006002	Cyclohexanecarboxylate-CoA ligase (also called cyclohex-1-ene-1-carboxylate:CoA ligase); Region: CHC_CoA_lg; cd05903
696406006003	acyl-activating enzyme (AAE) consensus motif; other site
696406006004	putative AMP binding site [chemical binding]; other site
696406006005	putative active site [active]
696406006006	putative CoA binding site [chemical binding]; other site
696406006007	phosphoenolpyruvate synthase; Validated; Region: PRK06464
696406006008	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
696406006009	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
696406006010	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
696406006011	PEP synthetase regulatory protein; Provisional; Region: PRK05339
696406006012	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
696406006013	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
696406006014	Hemin uptake protein [Inorganic ion transport and metabolism]; Region: HemP; COG4256
696406006015	Uncharacterized conserved protein [Function unknown]; Region: COG0397
696406006016	hypothetical protein; Validated; Region: PRK00029
696406006017	c-di-GMP phosphodiesterase class I (EAL domain) [Signal    transduction mechanisms]; Region: Rtn; COG2200
696406006018	NlpC/P60 family; Region: NLPC_P60; pfam00877
696406006019	vitamin B12-transporter ATPase; Provisional; Region: PRK03695
696406006020	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
696406006021	Walker A/P-loop; other site
696406006022	ATP binding site [chemical binding]; other site
696406006023	Q-loop/lid; other site
696406006024	ABC transporter signature motif; other site
696406006025	Walker B; other site
696406006026	D-loop; other site
696406006027	H-loop/switch region; other site
696406006028	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
696406006029	catalytic residues [active]
696406006030	dimer interface [polypeptide binding]; other site
696406006031	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
696406006032	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
696406006033	ABC-ATPase subunit  interface; other site
696406006034	dimer interface [polypeptide binding]; other site
696406006035	putative PBP binding regions; other site
696406006036	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
696406006037	IHF dimer interface [polypeptide binding]; other site
696406006038	IHF - DNA interface [nucleotide binding]; other site
696406006039	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
696406006040	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
696406006041	putative tRNA-binding site [nucleotide binding]; other site
696406006042	B3/4 domain; Region: B3_4; pfam03483
696406006043	tRNA synthetase B5 domain; Region: B5; smart00874
696406006044	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
696406006045	dimer interface [polypeptide binding]; other site
696406006046	motif 1; other site
696406006047	motif 3; other site
696406006048	motif 2; other site
696406006049	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
696406006050	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
696406006051	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
696406006052	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
696406006053	dimer interface [polypeptide binding]; other site
696406006054	motif 1; other site
696406006055	active site
696406006056	motif 2; other site
696406006057	motif 3; other site
696406006058	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
696406006059	23S rRNA binding site [nucleotide binding]; other site
696406006060	L21 binding site [polypeptide binding]; other site
696406006061	L13 binding site [polypeptide binding]; other site
696406006062	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
696406006063	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
696406006064	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
696406006065	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
696406006066	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
696406006067	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
696406006068	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
696406006069	active site
696406006070	dimer interface [polypeptide binding]; other site
696406006071	motif 1; other site
696406006072	motif 2; other site
696406006073	motif 3; other site
696406006074	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
696406006075	anticodon binding site; other site
696406006076	ShET2 enterotoxin, N-terminal region; Region: Toxin_15; pfam07906
696406006077	Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG3137
696406006078	6-phosphofructokinase 2; Provisional; Region: PRK10294
696406006079	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
696406006080	putative substrate binding site [chemical binding]; other site
696406006081	putative ATP binding site [chemical binding]; other site
696406006082	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
696406006083	Phosphotransferase enzyme family; Region: APH; pfam01636
696406006084	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
696406006085	active site
696406006086	ATP binding site [chemical binding]; other site
696406006087	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
696406006088	YniB-like protein; Region: YniB; pfam14002
696406006089	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
696406006090	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
696406006091	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696406006092	motif II; other site
696406006093	inner membrane protein; Provisional; Region: PRK11648
696406006094	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
696406006095	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
696406006096	cell division modulator; Provisional; Region: PRK10113
696406006097	hydroperoxidase II; Provisional; Region: katE; PRK11249
696406006098	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
696406006099	tetramer interface [polypeptide binding]; other site
696406006100	heme binding pocket [chemical binding]; other site
696406006101	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
696406006102	domain interactions; other site
696406006103	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
696406006104	putative active site [active]
696406006105	YdjC motif; other site
696406006106	Mg binding site [ion binding]; other site
696406006107	putative homodimer interface [polypeptide binding]; other site
696406006108	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
696406006109	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
696406006110	NAD binding site [chemical binding]; other site
696406006111	sugar binding site [chemical binding]; other site
696406006112	divalent metal binding site [ion binding]; other site
696406006113	tetramer (dimer of dimers) interface [polypeptide binding]; other site
696406006114	dimer interface [polypeptide binding]; other site
696406006115	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
696406006116	Cupin domain; Region: Cupin_2; pfam07883
696406006117	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406006118	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
696406006119	methionine cluster; other site
696406006120	active site
696406006121	phosphorylation site [posttranslational modification]
696406006122	metal binding site [ion binding]; metal-binding site
696406006123	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
696406006124	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
696406006125	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
696406006126	active site
696406006127	P-loop; other site
696406006128	phosphorylation site [posttranslational modification]
696406006129	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
696406006130	NAD+ synthetase; Region: nadE; TIGR00552
696406006131	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
696406006132	homodimer interface [polypeptide binding]; other site
696406006133	NAD binding pocket [chemical binding]; other site
696406006134	ATP binding pocket [chemical binding]; other site
696406006135	Mg binding site [ion binding]; other site
696406006136	active-site loop [active]
696406006137	nucleotide excision repair endonuclease; Provisional; Region: PRK10545
696406006138	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
696406006139	active site
696406006140	catalytic site [active]
696406006141	putative DNA binding site [nucleotide binding]; other site
696406006142	GIY-YIG motif/motif A; other site
696406006143	metal binding site [ion binding]; metal-binding site
696406006144	hypothetical protein; Provisional; Region: PRK11396
696406006145	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
696406006146	dimer interface [polypeptide binding]; other site
696406006147	Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855
696406006148	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
696406006149	putative active site [active]
696406006150	Zn binding site [ion binding]; other site
696406006151	succinylarginine dihydrolase; Provisional; Region: PRK13281
696406006152	succinylglutamic semialdehyde dehydrogenase; Reviewed; Region: astD; PRK09457
696406006153	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
696406006154	NAD(P) binding site [chemical binding]; other site
696406006155	catalytic residues [active]
696406006156	arginine succinyltransferase; Provisional; Region: PRK10456
696406006157	Arginine/ornithine N-succinyltransferase beta subunit [Amino acid transport and metabolism]; Region: AstA; COG3138
696406006158	bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381
696406006159	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
696406006160	inhibitor-cofactor binding pocket; inhibition site
696406006161	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406006162	catalytic residue [active]
696406006163	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
696406006164	putative catalytic site [active]
696406006165	putative phosphate binding site [ion binding]; other site
696406006166	active site
696406006167	metal binding site A [ion binding]; metal-binding site
696406006168	DNA binding site [nucleotide binding]
696406006169	putative AP binding site [nucleotide binding]; other site
696406006170	putative metal binding site B [ion binding]; other site
696406006171	Uncharacterized conserved protein [Function unknown]; Region: COG0398
696406006172	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
696406006173	Uncharacterized conserved protein [Function unknown]; Region: COG0398
696406006174	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
696406006175	Uncharacterized conserved protein [Function unknown]; Region: COG2128
696406006176	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
696406006177	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4134
696406006178	hypothetical protein; Provisional; Region: PRK11622
696406006179	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4135
696406006180	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406006181	dimer interface [polypeptide binding]; other site
696406006182	conserved gate region; other site
696406006183	putative PBP binding loops; other site
696406006184	ABC-ATPase subunit interface; other site
696406006185	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4136
696406006186	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
696406006187	Walker A/P-loop; other site
696406006188	ATP binding site [chemical binding]; other site
696406006189	Q-loop/lid; other site
696406006190	ABC transporter signature motif; other site
696406006191	Walker B; other site
696406006192	D-loop; other site
696406006193	H-loop/switch region; other site
696406006194	Rhodanese Homology Domain; Region: RHOD; smart00450
696406006195	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
696406006196	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
696406006197	active site residue [active]
696406006198	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
696406006199	active site residue [active]
696406006200	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
696406006201	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
696406006202	active site
696406006203	8-oxo-dGMP binding site [chemical binding]; other site
696406006204	nudix motif; other site
696406006205	metal binding site [ion binding]; metal-binding site
696406006206	Protein of unknown function (DUF1496); Region: DUF1496; pfam07383
696406006207	glutamate dehydrogenase; Provisional; Region: PRK09414
696406006208	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
696406006209	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
696406006210	NAD(P) binding site [chemical binding]; other site
696406006211	hypothetical protein; Provisional; Region: PRK11380
696406006212	DNA topoisomerase III; Provisional; Region: PRK07726
696406006213	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
696406006214	active site
696406006215	putative interdomain interaction site [polypeptide binding]; other site
696406006216	putative metal-binding site [ion binding]; other site
696406006217	putative nucleotide binding site [chemical binding]; other site
696406006218	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
696406006219	domain I; other site
696406006220	DNA binding groove [nucleotide binding]
696406006221	phosphate binding site [ion binding]; other site
696406006222	domain II; other site
696406006223	domain III; other site
696406006224	nucleotide binding site [chemical binding]; other site
696406006225	catalytic site [active]
696406006226	domain IV; other site
696406006227	selenophosphate synthetase; Provisional; Region: PRK00943
696406006228	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
696406006229	dimerization interface [polypeptide binding]; other site
696406006230	putative ATP binding site [chemical binding]; other site
696406006231	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
696406006232	putative FMN binding site [chemical binding]; other site
696406006233	protease 4; Provisional; Region: PRK10949
696406006234	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
696406006235	tandem repeat interface [polypeptide binding]; other site
696406006236	oligomer interface [polypeptide binding]; other site
696406006237	active site residues [active]
696406006238	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019
696406006239	tandem repeat interface [polypeptide binding]; other site
696406006240	oligomer interface [polypeptide binding]; other site
696406006241	active site residues [active]
696406006242	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
696406006243	homodimer interface [polypeptide binding]; other site
696406006244	active site
696406006245	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
696406006246	Isochorismatase family; Region: Isochorismatase; pfam00857
696406006247	catalytic triad [active]
696406006248	metal binding site [ion binding]; metal-binding site
696406006249	conserved cis-peptide bond; other site
696406006250	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
696406006251	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406006252	putative substrate translocation pore; other site
696406006253	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406006254	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
696406006255	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
696406006256	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
696406006257	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
696406006258	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
696406006259	active site
696406006260	catalytic tetrad [active]
696406006261	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
696406006262	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
696406006263	substrate binding site [chemical binding]; other site
696406006264	ATP binding site [chemical binding]; other site
696406006265	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
696406006266	intersubunit interface [polypeptide binding]; other site
696406006267	active site
696406006268	zinc binding site [ion binding]; other site
696406006269	Na+ binding site [ion binding]; other site
696406006270	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
696406006271	Sorbitol dehydrogenase; Region: sorbitol_DH; cd05285
696406006272	inhibitor binding site; inhibition site
696406006273	catalytic Zn binding site [ion binding]; other site
696406006274	structural Zn binding site [ion binding]; other site
696406006275	NADP binding site [chemical binding]; other site
696406006276	tetramer interface [polypeptide binding]; other site
696406006277	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406006278	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406006279	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
696406006280	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH4; cd08258
696406006281	putative NAD(P) binding site [chemical binding]; other site
696406006282	catalytic Zn binding site [ion binding]; other site
696406006283	structural Zn binding site [ion binding]; other site
696406006284	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3139
696406006285	methionine sulfoxide reductase B; Provisional; Region: PRK00222
696406006286	SelR domain; Region: SelR; pfam01641
696406006287	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
696406006288	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
696406006289	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
696406006290	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
696406006291	active site
696406006292	phosphate binding residues; other site
696406006293	catalytic residues [active]
696406006294	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
696406006295	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
696406006296	active site
696406006297	catalytic tetrad [active]
696406006298	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
696406006299	PrkA family serine protein kinase; Provisional; Region: PRK15455
696406006300	AAA ATPase domain; Region: AAA_16; pfam13191
696406006301	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
696406006302	hypothetical protein; Provisional; Region: PRK05325
696406006303	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
696406006304	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
696406006305	metal binding site [ion binding]; metal-binding site
696406006306	active site
696406006307	I-site; other site
696406006308	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
696406006309	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
696406006310	metal binding site [ion binding]; metal-binding site
696406006311	active site
696406006312	I-site; other site
696406006313	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
696406006314	putative deacylase active site [active]
696406006315	Predicted membrane protein [Function unknown]; Region: COG2707
696406006316	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
696406006317	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406006318	cyanate transporter; Region: CynX; TIGR00896
696406006319	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406006320	Uncharacterized conserved protein [Function unknown]; Region: COG3189
696406006321	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
696406006322	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
696406006323	Domain of unknown function (DUF333); Region: DUF333; pfam03891
696406006324	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
696406006325	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
696406006326	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
696406006327	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
696406006328	metal binding site [ion binding]; metal-binding site
696406006329	active site
696406006330	I-site; other site
696406006331	hypothetical protein; Provisional; Region: PRK10457
696406006332	Domain of unknown function (DUF1869); Region: DUF1869; pfam08956
696406006333	Domain of unknown function (DUF1971); Region: DUF1971; cl17717
696406006334	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
696406006335	leucine export protein LeuE; Provisional; Region: PRK10958
696406006336	transcriptional activator TtdR; Provisional; Region: PRK09801
696406006337	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406006338	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
696406006339	putative effector binding pocket; other site
696406006340	putative dimerization interface [polypeptide binding]; other site
696406006341	Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473
696406006342	tartrate dehydrogenase; Region: TTC; TIGR02089
696406006343	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
696406006344	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
696406006345	[2Fe-2S] cluster binding site [ion binding]; other site
696406006346	C-terminal catalytic domain of the oxygenase alpha subunit of an uncharacterized subgroup of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases; Region: RHO_alpha_C_2; cd08886
696406006347	putative alpha subunit interface [polypeptide binding]; other site
696406006348	putative active site [active]
696406006349	putative substrate binding site [chemical binding]; other site
696406006350	Fe binding site [ion binding]; other site
696406006351	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018
696406006352	Phthalate dioxygenase reductase (PDR) is an FMN-dependent reductase that mediates electron transfer from NADH to FMN to an iron sulfur cluster. PDR has an an N-terminal  ferrredoxin reductase (FNR)-like NAD(H) binding domain and a C-terminal iron-sulfur; Region: PDR_like; cd06185
696406006353	FMN-binding pocket [chemical binding]; other site
696406006354	flavin binding motif; other site
696406006355	phosphate binding motif [ion binding]; other site
696406006356	beta-alpha-beta structure motif; other site
696406006357	NAD binding pocket [chemical binding]; other site
696406006358	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
696406006359	catalytic loop [active]
696406006360	iron binding site [ion binding]; other site
696406006361	ribonuclease D; Provisional; Region: PRK10829
696406006362	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
696406006363	catalytic site [active]
696406006364	putative active site [active]
696406006365	putative substrate binding site [chemical binding]; other site
696406006366	Helicase and RNase D C-terminal; Region: HRDC; smart00341
696406006367	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
696406006368	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
696406006369	acyl-activating enzyme (AAE) consensus motif; other site
696406006370	putative AMP binding site [chemical binding]; other site
696406006371	putative active site [active]
696406006372	putative CoA binding site [chemical binding]; other site
696406006373	outer membrane lipoprotein, Slp family; Region: slp; TIGR00752
696406006374	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
696406006375	Glycoprotease family; Region: Peptidase_M22; pfam00814
696406006376	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
696406006377	DEAD/DEAH box helicase; Region: DEAD; pfam00270
696406006378	DEAD_2; Region: DEAD_2; pfam06733
696406006379	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
696406006380	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
696406006381	homotrimer interaction site [polypeptide binding]; other site
696406006382	putative active site [active]
696406006383	Domain of unknown function (DUF1889); Region: DUF1889; pfam08986
696406006384	hypothetical protein; Provisional; Region: PRK05114
696406006385	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
696406006386	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
696406006387	aminodeoxychorismate synthase, component I, bacterial clade; Region: pabB; TIGR00553
696406006388	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
696406006389	putative active site [active]
696406006390	putative CoA binding site [chemical binding]; other site
696406006391	nudix motif; other site
696406006392	metal binding site [ion binding]; metal-binding site
696406006393	L-serine deaminase; Provisional; Region: PRK15023
696406006394	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
696406006395	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
696406006396	phage resistance protein; Provisional; Region: PRK10551
696406006397	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
696406006398	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
696406006399	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
696406006400	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
696406006401	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
696406006402	Transporter associated domain; Region: CorC_HlyC; smart01091
696406006403	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
696406006404	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
696406006405	active pocket/dimerization site; other site
696406006406	active site
696406006407	phosphorylation site [posttranslational modification]
696406006408	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
696406006409	active site
696406006410	phosphorylation site [posttranslational modification]
696406006411	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
696406006412	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
696406006413	Predicted membrane protein [Function unknown]; Region: COG4811
696406006414	hypothetical protein; Provisional; Region: PRK11469
696406006415	Domain of unknown function DUF; Region: DUF204; pfam02659
696406006416	Domain of unknown function DUF; Region: DUF204; pfam02659
696406006417	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
696406006418	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406006419	S-adenosylmethionine binding site [chemical binding]; other site
696406006420	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
696406006421	DNA-binding site [nucleotide binding]; DNA binding site
696406006422	RNA-binding motif; other site
696406006423	Protein of unknown function (DUF2627); Region: DUF2527; pfam10736
696406006424	YebO-like protein; Region: YebO; pfam13974
696406006425	PhoPQ regulatory protein; Provisional; Region: PRK10299
696406006426	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
696406006427	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
696406006428	dimerization interface [polypeptide binding]; other site
696406006429	putative Zn2+ binding site [ion binding]; other site
696406006430	putative DNA binding site [nucleotide binding]; other site
696406006431	Bacterial transcriptional regulator; Region: IclR; pfam01614
696406006432	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406006433	Major Facilitator Superfamily; Region: MFS_1; pfam07690
696406006434	putative substrate translocation pore; other site
696406006435	Predicted integral membrane protein [Function unknown]; Region: COG5521
696406006436	heat shock protein HtpX; Provisional; Region: PRK05457
696406006437	carboxy-terminal protease; Provisional; Region: PRK11186
696406006438	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
696406006439	protein binding site [polypeptide binding]; other site
696406006440	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
696406006441	Catalytic dyad [active]
696406006442	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
696406006443	ProP expression regulator; Provisional; Region: PRK04950
696406006444	ProQ/FINO family; Region: ProQ; pfam04352
696406006445	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
696406006446	GAF domain; Region: GAF_2; pfam13185
696406006447	integral membrane protein, PqiA family; Region: pqiA_fam; TIGR00155
696406006448	Paraquat-inducible protein A; Region: PqiA; pfam04403
696406006449	Paraquat-inducible protein A; Region: PqiA; pfam04403
696406006450	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
696406006451	mce related protein; Region: MCE; pfam02470
696406006452	mce related protein; Region: MCE; pfam02470
696406006453	mce related protein; Region: MCE; pfam02470
696406006454	mce related protein; Region: MCE; pfam02470
696406006455	mce related protein; Region: MCE; pfam02470
696406006456	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
696406006457	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406006458	S-adenosylmethionine binding site [chemical binding]; other site
696406006459	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
696406006460	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
696406006461	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
696406006462	serine/threonine protein phosphatase 1; Provisional; Region: pphA; PRK11439
696406006463	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
696406006464	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
696406006465	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
696406006466	hypothetical protein; Provisional; Region: PRK10301
696406006467	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
696406006468	Predicted amidohydrolase [General function prediction only]; Region: COG0388
696406006469	Carbon-nitrogen hydrolase; Region: CN_hydrolase; pfam00795
696406006470	exodeoxyribonuclease X; Provisional; Region: PRK07983
696406006471	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
696406006472	active site
696406006473	catalytic site [active]
696406006474	substrate binding site [chemical binding]; other site
696406006475	protease 2; Provisional; Region: PRK10115
696406006476	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
696406006477	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2979
696406006478	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
696406006479	putative metal binding site [ion binding]; other site
696406006480	hypothetical protein; Provisional; Region: PRK13680
696406006481	DNA damage-inducible protein YebG; Provisional; Region: PRK10061
696406006482	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
696406006483	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
696406006484	ATP-grasp domain; Region: ATP-grasp; pfam02222
696406006485	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
696406006486	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
696406006487	active site
696406006488	intersubunit interface [polypeptide binding]; other site
696406006489	catalytic residue [active]
696406006490	phosphogluconate dehydratase; Validated; Region: PRK09054
696406006491	6-phosphogluconate dehydratase; Region: edd; TIGR01196
696406006492	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
696406006493	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
696406006494	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
696406006495	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
696406006496	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
696406006497	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
696406006498	putative active site [active]
696406006499	pyruvate kinase; Provisional; Region: PRK05826
696406006500	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
696406006501	domain interfaces; other site
696406006502	active site
696406006503	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
696406006504	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
696406006505	putative acyl-acceptor binding pocket; other site
696406006506	putative peptidase; Provisional; Region: PRK11649
696406006507	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
696406006508	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
696406006509	Peptidase family M23; Region: Peptidase_M23; pfam01551
696406006510	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
696406006511	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
696406006512	metal binding site [ion binding]; metal-binding site
696406006513	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
696406006514	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
696406006515	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
696406006516	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
696406006517	ABC-ATPase subunit  interface; other site
696406006518	dimer interface [polypeptide binding]; other site
696406006519	putative PBP binding regions; other site
696406006520	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
696406006521	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406006522	Walker A motif; other site
696406006523	ATP binding site [chemical binding]; other site
696406006524	Walker B motif; other site
696406006525	arginine finger; other site
696406006526	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
696406006527	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
696406006528	RuvA N terminal domain; Region: RuvA_N; pfam01330
696406006529	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
696406006530	hypothetical protein; Provisional; Region: PRK11470
696406006531	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
696406006532	active site
696406006533	putative DNA-binding cleft [nucleotide binding]; other site
696406006534	dimer interface [polypeptide binding]; other site
696406006535	hypothetical protein; Validated; Region: PRK00110
696406006536	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
696406006537	nudix motif; other site
696406006538	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
696406006539	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
696406006540	dimer interface [polypeptide binding]; other site
696406006541	anticodon binding site; other site
696406006542	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
696406006543	homodimer interface [polypeptide binding]; other site
696406006544	motif 1; other site
696406006545	active site
696406006546	motif 2; other site
696406006547	GAD domain; Region: GAD; pfam02938
696406006548	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
696406006549	motif 3; other site
696406006550	Isochorismatase family; Region: Isochorismatase; pfam00857
696406006551	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
696406006552	catalytic triad [active]
696406006553	conserved cis-peptide bond; other site
696406006554	hypothetical protein; Provisional; Region: PRK10302
696406006555	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
696406006556	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406006557	S-adenosylmethionine binding site [chemical binding]; other site
696406006558	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406006559	S-adenosylmethionine binding site [chemical binding]; other site
696406006560	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
696406006561	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
696406006562	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
696406006563	molybdopterin cofactor binding site [chemical binding]; other site
696406006564	substrate binding site [chemical binding]; other site
696406006565	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
696406006566	molybdopterin cofactor binding site; other site
696406006567	trimethylamine-N-oxide reductase c-type cytochrome TorC; Region: torC; TIGR02162
696406006568	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
696406006569	copper homeostasis protein CutC; Provisional; Region: PRK11572
696406006570	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
696406006571	putative metal binding site [ion binding]; other site
696406006572	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
696406006573	arginyl-tRNA synthetase; Region: argS; TIGR00456
696406006574	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
696406006575	active site
696406006576	HIGH motif; other site
696406006577	KMSK motif region; other site
696406006578	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
696406006579	tRNA binding surface [nucleotide binding]; other site
696406006580	anticodon binding site; other site
696406006581	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3755
696406006582	Flagellar protein FlhE; Region: FlhE; pfam06366
696406006583	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
696406006584	FHIPEP family; Region: FHIPEP; pfam00771
696406006585	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
696406006586	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
696406006587	chemotaxis regulator CheZ; Provisional; Region: PRK11166
696406006588	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
696406006589	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406006590	active site
696406006591	phosphorylation site [posttranslational modification]
696406006592	intermolecular recognition site; other site
696406006593	dimerization interface [polypeptide binding]; other site
696406006594	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
696406006595	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406006596	active site
696406006597	phosphorylation site [posttranslational modification]
696406006598	intermolecular recognition site; other site
696406006599	dimerization interface [polypeptide binding]; other site
696406006600	CheB methylesterase; Region: CheB_methylest; pfam01339
696406006601	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
696406006602	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
696406006603	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406006604	S-adenosylmethionine binding site [chemical binding]; other site
696406006605	methyl-accepting protein IV; Provisional; Region: PRK09793
696406006606	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
696406006607	dimer interface [polypeptide binding]; other site
696406006608	ligand binding site [chemical binding]; other site
696406006609	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
696406006610	dimerization interface [polypeptide binding]; other site
696406006611	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
696406006612	dimer interface [polypeptide binding]; other site
696406006613	putative CheW interface [polypeptide binding]; other site
696406006614	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
696406006615	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
696406006616	dimer interface [polypeptide binding]; other site
696406006617	ligand binding site [chemical binding]; other site
696406006618	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
696406006619	dimerization interface [polypeptide binding]; other site
696406006620	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
696406006621	dimer interface [polypeptide binding]; other site
696406006622	putative CheW interface [polypeptide binding]; other site
696406006623	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
696406006624	putative CheA interaction surface; other site
696406006625	chemotaxis protein CheA; Provisional; Region: PRK10547
696406006626	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
696406006627	putative binding surface; other site
696406006628	active site
696406006629	CheY binding; Region: CheY-binding; pfam09078
696406006630	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
696406006631	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406006632	ATP binding site [chemical binding]; other site
696406006633	Mg2+ binding site [ion binding]; other site
696406006634	G-X-G motif; other site
696406006635	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
696406006636	flagellar motor protein MotB; Validated; Region: motB; PRK09041
696406006637	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
696406006638	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
696406006639	ligand binding site [chemical binding]; other site
696406006640	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
696406006641	flagellar motor protein MotA; Validated; Region: PRK09110
696406006642	transcriptional activator FlhC; Provisional; Region: PRK12722
696406006643	transcriptional activator FlhD; Provisional; Region: PRK02909
696406006644	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
696406006645	Ligand Binding Site [chemical binding]; other site
696406006646	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
696406006647	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
696406006648	active site
696406006649	homotetramer interface [polypeptide binding]; other site
696406006650	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187
696406006651	Trehalose-6-phosphatase [Carbohydrate transport and metabolism]; Region: OtsB; COG1877
696406006652	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
696406006653	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
696406006654	TM-ABC transporter signature motif; other site
696406006655	L-arabinose transporter ATP-binding protein; Provisional; Region: araG; PRK11288
696406006656	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
696406006657	Walker A/P-loop; other site
696406006658	ATP binding site [chemical binding]; other site
696406006659	Q-loop/lid; other site
696406006660	ABC transporter signature motif; other site
696406006661	Walker B; other site
696406006662	D-loop; other site
696406006663	H-loop/switch region; other site
696406006664	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
696406006665	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
696406006666	Periplasmic L-arabinose-binding protein (ABP), a member of a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein superfamily; Region: PBP1_arabinose_binding; cd01540
696406006667	ligand binding site [chemical binding]; other site
696406006668	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
696406006669	Ferritin-like domain; Region: Ferritin; pfam00210
696406006670	ferroxidase diiron center [ion binding]; other site
696406006671	Protein of unknown function (DUF2766); Region: DUF2766; pfam10964
696406006672	YecR-like lipoprotein; Region: YecR; pfam13992
696406006673	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
696406006674	Ferritin-like domain; Region: Ferritin; pfam00210
696406006675	ferroxidase diiron center [ion binding]; other site
696406006676	probable metal-binding protein; Region: matur_matur; TIGR03853
696406006677	tyrosine transporter TyrP; Provisional; Region: PRK15132
696406006678	aromatic amino acid transport protein; Region: araaP; TIGR00837
696406006679	hypothetical protein; Provisional; Region: PRK10396
696406006680	yecA family protein; Region: ygfB_yecA; TIGR02292
696406006681	SEC-C motif; Region: SEC-C; pfam02810
696406006682	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
696406006683	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
696406006684	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
696406006685	GIY-YIG motif/motif A; other site
696406006686	active site
696406006687	catalytic site [active]
696406006688	putative DNA binding site [nucleotide binding]; other site
696406006689	metal binding site [ion binding]; metal-binding site
696406006690	UvrB/uvrC motif; Region: UVR; pfam02151
696406006691	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
696406006692	Helix-hairpin-helix motif; Region: HHH; pfam00633
696406006693	response regulator; Provisional; Region: PRK09483
696406006694	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406006695	active site
696406006696	phosphorylation site [posttranslational modification]
696406006697	intermolecular recognition site; other site
696406006698	dimerization interface [polypeptide binding]; other site
696406006699	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
696406006700	DNA binding residues [nucleotide binding]
696406006701	dimerization interface [polypeptide binding]; other site
696406006702	hypothetical protein; Provisional; Region: PRK10613
696406006703	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
696406006704	Autoinducer binding domain; Region: Autoind_bind; pfam03472
696406006705	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
696406006706	DNA binding residues [nucleotide binding]
696406006707	dimerization interface [polypeptide binding]; other site
696406006708	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
696406006709	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
696406006710	Walker A/P-loop; other site
696406006711	ATP binding site [chemical binding]; other site
696406006712	Q-loop/lid; other site
696406006713	ABC transporter signature motif; other site
696406006714	Walker B; other site
696406006715	D-loop; other site
696406006716	H-loop/switch region; other site
696406006717	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
696406006718	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406006719	dimer interface [polypeptide binding]; other site
696406006720	conserved gate region; other site
696406006721	putative PBP binding loops; other site
696406006722	ABC-ATPase subunit interface; other site
696406006723	D-cysteine desulfhydrase; Validated; Region: PRK03910
696406006724	Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449
696406006725	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406006726	catalytic residue [active]
696406006727	cystine transporter subunit; Provisional; Region: PRK11260
696406006728	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
696406006729	substrate binding pocket [chemical binding]; other site
696406006730	membrane-bound complex binding site; other site
696406006731	hinge residues; other site
696406006732	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
696406006733	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
696406006734	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
696406006735	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
696406006736	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
696406006737	DNA binding residues [nucleotide binding]
696406006738	flagellin; Validated; Region: PRK06819
696406006739	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
696406006740	Flagellin D3 domain; Region: Flagellin_D3; pfam08884
696406006741	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
696406006742	flagellar capping protein; Reviewed; Region: fliD; PRK08032
696406006743	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
696406006744	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
696406006745	Flagellar protein FliS; Region: FliS; cl00654
696406006746	flagellar biosynthesis protein FliT; Provisional; Region: PRK10548
696406006747	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
696406006748	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
696406006749	active site
696406006750	Na/Ca binding site [ion binding]; other site
696406006751	catalytic site [active]
696406006752	lipoprotein; Provisional; Region: PRK10397
696406006753	putative inner membrane protein; Provisional; Region: PRK11099
696406006754	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
696406006755	CPxP  motif; other site
696406006756	hypothetical protein; Provisional; Region: PRK09951
696406006757	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
696406006758	multidrug efflux protein; Reviewed; Region: emrE; PRK09541
696406006759	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
696406006760	flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF); Region: fliF; TIGR00206
696406006761	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
696406006762	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
696406006763	flagellar motor switch protein FliG; Region: fliG; TIGR00207
696406006764	FliG C-terminal domain; Region: FliG_C; pfam01706
696406006765	flagellar assembly protein H; Validated; Region: fliH; PRK05687
696406006766	Essential protein Yae1, N terminal; Region: Yae1_N; pfam09811
696406006767	Flagellar assembly protein FliH; Region: FliH; pfam02108
696406006768	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
696406006769	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
696406006770	Walker A motif/ATP binding site; other site
696406006771	Walker B motif; other site
696406006772	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
696406006773	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
696406006774	Flagellar hook-length control protein [Cell motility and secretion]; Region: FliK; COG3144
696406006775	flagellar hook-length control protein; Provisional; Region: PRK10118
696406006776	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
696406006777	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
696406006778	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
696406006779	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
696406006780	flagellar motor switch protein; Validated; Region: fliN; PRK05698
696406006781	flagellar biosynthesis protein FliO; Provisional; Region: PRK11486
696406006782	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
696406006783	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
696406006784	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
696406006785	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
696406006786	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
696406006787	DNA binding residues [nucleotide binding]
696406006788	dimerization interface [polypeptide binding]; other site
696406006789	hypothetical protein; Provisional; Region: PRK10708
696406006790	Protein of unknown function (DUF2525); Region: DUF2525; pfam10733
696406006791	mannosyl-3-phosphoglycerate phosphatase; Reviewed; Region: PRK03669
696406006792	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696406006793	active site
696406006794	motif I; other site
696406006795	motif II; other site
696406006796	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
696406006797	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
696406006798	metal binding site [ion binding]; metal-binding site
696406006799	active site
696406006800	I-site; other site
696406006801	Uncharacterized small protein [Function unknown]; Region: COG5475
696406006802	hypothetical protein; Provisional; Region: PRK10062
696406006803	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
696406006804	EamA-like transporter family; Region: EamA; pfam00892
696406006805	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
696406006806	additional DNA contacts [nucleotide binding]; other site
696406006807	mismatch recognition site; other site
696406006808	active site
696406006809	zinc binding site [ion binding]; other site
696406006810	DNA intercalation site [nucleotide binding]; other site
696406006811	DNA cytosine methylase; Provisional; Region: PRK10458
696406006812	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
696406006813	cofactor binding site; other site
696406006814	DNA binding site [nucleotide binding]
696406006815	substrate interaction site [chemical binding]; other site
696406006816	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
696406006817	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
696406006818	Zn2+ binding site [ion binding]; other site
696406006819	Mg2+ binding site [ion binding]; other site
696406006820	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
696406006821	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
696406006822	Helix-turn-helix domain; Region: HTH_38; pfam13936
696406006823	Integrase core domain; Region: rve; pfam00665
696406006824	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
696406006825	Integrase core domain; Region: rve; pfam00665
696406006826	Integrase core domain; Region: rve_3; pfam13683
696406006827	chaperone protein HchA; Provisional; Region: PRK04155
696406006828	Type 1 glutamine amidotransferase (GATase1)-like domain found in Escherichia coli Hsp31 protein (EcHsp31); Region: GATase1_EcHsp31_like; cd03148
696406006829	dimer interface [polypeptide binding]; other site
696406006830	metal binding site [ion binding]; metal-binding site
696406006831	potential oxyanion hole; other site
696406006832	potential catalytic triad [active]
696406006833	conserved cys residue [active]
696406006834	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
696406006835	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
696406006836	dimer interface [polypeptide binding]; other site
696406006837	phosphorylation site [posttranslational modification]
696406006838	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406006839	ATP binding site [chemical binding]; other site
696406006840	Mg2+ binding site [ion binding]; other site
696406006841	G-X-G motif; other site
696406006842	transcriptional regulatory protein YedW; Provisional; Region: PRK11517
696406006843	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406006844	active site
696406006845	phosphorylation site [posttranslational modification]
696406006846	intermolecular recognition site; other site
696406006847	dimerization interface [polypeptide binding]; other site
696406006848	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
696406006849	DNA binding site [nucleotide binding]
696406006850	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
696406006851	active site
696406006852	homotetramer interface [polypeptide binding]; other site
696406006853	TMAO/DMSO reductase; Reviewed; Region: PRK05363
696406006854	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
696406006855	Moco binding site; other site
696406006856	metal coordination site [ion binding]; other site
696406006857	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
696406006858	zinc/cadmium-binding protein; Provisional; Region: PRK10306
696406006859	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
696406006860	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
696406006861	Phage Tail Collar Domain; Region: Collar; pfam07484
696406006862	Membrane-associated apoptosis protein; Region: Nckap1; pfam09735
696406006863	phage protein, HK97 gp10 family; Region: phge_HK97_gp10; TIGR01725
696406006864	Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054
696406006865	oligomerization interface [polypeptide binding]; other site
696406006866	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
696406006867	Phage capsid family; Region: Phage_capsid; pfam05065
696406006868	Caudovirus prohead protease; Region: Peptidase_U35; cl01521
696406006869	Phage-related protein [Function unknown]; Region: COG4695
696406006870	Phage portal protein; Region: Phage_portal; pfam04860
696406006871	Phage terminase-like protein, large subunit [General function prediction only]; Region: COG4626
696406006872	Phage terminase, small subunit; Region: Terminase_4; pfam05119
696406006873	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
696406006874	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
696406006875	active site
696406006876	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539
696406006877	Protein of unknown function (DUF754); Region: DUF754; pfam05449
696406006878	tellurite resistance protein terB; Region: terB; cd07176
696406006879	putative metal binding site [ion binding]; other site
696406006880	Phage antitermination protein Q; Region: Phage_antiter_Q; pfam06323
696406006881	Holliday junction resolvase [DNA replication, recombination, and repair]; Region: Rus; COG4570
696406006882	Protein of unknown function (DUF968); Region: DUF968; pfam06147
696406006883	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
696406006884	primosomal protein DnaI; Provisional; Region: PRK02854
696406006885	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
696406006886	Protein of unknown function (DUF1391); Region: DUF1391; pfam07151
696406006887	DicB protein; Region: DicB; pfam05358
696406006888	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
696406006889	exonuclease VIII; Reviewed; Region: PRK09709
696406006890	Enterobacterial exodeoxyribonuclease VIII; Region: Exonuc_VIII; pfam06630
696406006891	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
696406006892	active site
696406006893	catalytic site [active]
696406006894	substrate binding site [chemical binding]; other site
696406006895	Domain of unknown function (DUF4224); Region: DUF4224; pfam13986
696406006896	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
696406006897	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
696406006898	active site
696406006899	DNA binding site [nucleotide binding]
696406006900	Int/Topo IB signature motif; other site
696406006901	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
696406006902	potential frameshift: common BLAST hit: gi|254793681|ref|YP_003078518.1| adhesin
696406006903	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cl00107
696406006904	potential frameshift: common BLAST hit: gi|218554554|ref|YP_002387467.1| adhesin
696406006905	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
696406006906	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
696406006907	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
696406006908	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
696406006909	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
696406006910	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
696406006911	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
696406006912	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
696406006913	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
696406006914	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
696406006915	shikimate transporter; Provisional; Region: PRK09952
696406006916	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406006917	putative substrate translocation pore; other site
696406006918	AMP nucleosidase; Provisional; Region: PRK08292
696406006919	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
696406006920	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
696406006921	hypothetical protein; Provisional; Region: PRK12378
696406006922	MATE family multidrug exporter; Provisional; Region: PRK10189
696406006923	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
696406006924	transcriptional regulator Cbl; Reviewed; Region: cbl; PRK12679
696406006925	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406006926	The C-terminal substrate binding domain of LysR-type transcriptional regulator Cbl, which is required for expression of sulfate starvation-inducible (ssi) genes, contains the type 2 periplasmic binding fold; Region: PBP2_Cbl; cd08444
696406006927	putative substrate binding site [chemical binding]; other site
696406006928	dimerization interface [polypeptide binding]; other site
696406006929	nitrogen assimilation transcriptional regulator; Provisional; Region: PRK11233
696406006930	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406006931	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
696406006932	putative dimerization interface [polypeptide binding]; other site
696406006933	L,D-transpeptidase; Provisional; Region: PRK10190
696406006934	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
696406006935	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
696406006936	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
696406006937	putative dimer interface [polypeptide binding]; other site
696406006938	active site pocket [active]
696406006939	putative cataytic base [active]
696406006940	cobalamin 5'-phosphate synthase/cobalamin synthase; Region: cobS; TIGR00317
696406006941	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
696406006942	homotrimer interface [polypeptide binding]; other site
696406006943	Walker A motif; other site
696406006944	GTP binding site [chemical binding]; other site
696406006945	Walker B motif; other site
696406006946	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
696406006947	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
696406006948	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
696406006949	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
696406006950	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
696406006951	substrate binding site [chemical binding]; other site
696406006952	dimer interface [polypeptide binding]; other site
696406006953	ATP binding site [chemical binding]; other site
696406006954	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
696406006955	IS2 transposase TnpB; Reviewed; Region: PRK09409
696406006956	HTH-like domain; Region: HTH_21; pfam13276
696406006957	Integrase core domain; Region: rve; pfam00665
696406006958	Integrase core domain; Region: rve_3; pfam13683
696406006959	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
696406006960	active site
696406006961	substrate binding pocket [chemical binding]; other site
696406006962	homodimer interaction site [polypeptide binding]; other site
696406006963	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; cl08040
696406006964	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; cl08040
696406006965	Transposase; Region: HTH_Tnp_1; cl17663
696406006966	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
696406006967	putative transposase OrfB; Reviewed; Region: PHA02517
696406006968	HTH-like domain; Region: HTH_21; pfam13276
696406006969	Integrase core domain; Region: rve; pfam00665
696406006970	Integrase core domain; Region: rve_2; pfam13333
696406006971	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
696406006972	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
696406006973	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
696406006974	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; pfam05930
696406006975	Predicted GTPase [General function prediction only]; Region: COG3596
696406006976	YfjP GTPase; Region: YfjP; cd11383
696406006977	G1 box; other site
696406006978	GTP/Mg2+ binding site [chemical binding]; other site
696406006979	Switch I region; other site
696406006980	G2 box; other site
696406006981	Switch II region; other site
696406006982	G3 box; other site
696406006983	G4 box; other site
696406006984	G5 box; other site
696406006985	hypothetical protein; Provisional; Region: PRK09866
696406006986	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
696406006987	G1 box; other site
696406006988	GTP/Mg2+ binding site [chemical binding]; other site
696406006989	G2 box; other site
696406006990	Switch I region; other site
696406006991	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
696406006992	G3 box; other site
696406006993	Switch II region; other site
696406006994	GTP/Mg2+ binding site [chemical binding]; other site
696406006995	G4 box; other site
696406006996	G5 box; other site
696406006997	YjcZ-like protein; Region: YjcZ; pfam13990
696406006998	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
696406006999	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
696406007000	nucleophile elbow; other site
696406007001	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
696406007002	Domain of unknown function (DUF932); Region: DUF932; pfam06067
696406007003	Antirestriction protein; Region: Antirestrict; pfam03230
696406007004	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
696406007005	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
696406007006	MPN+ (JAMM) motif; other site
696406007007	Zinc-binding site [ion binding]; other site
696406007008	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
696406007009	Protein of unknown function (DUF987); Region: DUF987; pfam06174
696406007010	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
696406007011	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
696406007012	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
696406007013	hypothetical protein; Provisional; Region: PRK05423
696406007014	Predicted membrane protein [Function unknown]; Region: COG1289
696406007015	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
696406007016	DNA gyrase inhibitor; Provisional; Region: PRK10016
696406007017	D-alanyl-D-alanine carboxypeptidase; Provisional; Region: dacD; PRK11397
696406007018	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
696406007019	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
696406007020	exonuclease I; Provisional; Region: sbcB; PRK11779
696406007021	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
696406007022	active site
696406007023	catalytic site [active]
696406007024	substrate binding site [chemical binding]; other site
696406007025	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
696406007026	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291
696406007027	CPxP  motif; other site
696406007028	putative selenium metabolism protein, YedE family; Region: seleno_YedE; TIGR04112
696406007029	Sulphur transport; Region: Sulf_transp; pfam04143
696406007030	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
696406007031	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406007032	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
696406007033	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
696406007034	dimerization interface [polypeptide binding]; other site
696406007035	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
696406007036	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
696406007037	putative NAD(P) binding site [chemical binding]; other site
696406007038	Plasmid encoded toxin Txe; Region: Plasmid_Txe; pfam06769
696406007039	antitoxin YefM; Provisional; Region: PRK11409
696406007040	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
696406007041	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
696406007042	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
696406007043	Histidinol dehydrogenase; Region: Histidinol_dh; pfam00815
696406007044	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
696406007045	NAD binding site [chemical binding]; other site
696406007046	dimerization interface [polypeptide binding]; other site
696406007047	product binding site; other site
696406007048	substrate binding site [chemical binding]; other site
696406007049	zinc binding site [ion binding]; other site
696406007050	catalytic residues [active]
696406007051	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
696406007052	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
696406007053	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406007054	homodimer interface [polypeptide binding]; other site
696406007055	catalytic residue [active]
696406007056	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
696406007057	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696406007058	active site
696406007059	motif I; other site
696406007060	motif II; other site
696406007061	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
696406007062	putative active site pocket [active]
696406007063	4-fold oligomerization interface [polypeptide binding]; other site
696406007064	metal binding residues [ion binding]; metal-binding site
696406007065	3-fold/trimer interface [polypeptide binding]; other site
696406007066	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
696406007067	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
696406007068	putative active site [active]
696406007069	oxyanion strand; other site
696406007070	catalytic triad [active]
696406007071	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
696406007072	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
696406007073	catalytic residues [active]
696406007074	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
696406007075	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
696406007076	substrate binding site [chemical binding]; other site
696406007077	glutamase interaction surface [polypeptide binding]; other site
696406007078	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
696406007079	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
696406007080	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
696406007081	metal binding site [ion binding]; metal-binding site
696406007082	chain length determinant protein WzzB; Provisional; Region: PRK15471
696406007083	Chain length determinant protein; Region: Wzz; pfam02706
696406007084	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
696406007085	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
696406007086	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
696406007087	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
696406007088	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
696406007089	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
696406007090	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
696406007091	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
696406007092	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_6; cd04955
696406007093	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
696406007094	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
696406007095	active site
696406007096	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
696406007097	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
696406007098	glucose-1-phosphate thymidylyltransferase RfbA; Provisional; Region: PRK15480
696406007099	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
696406007100	substrate binding site; other site
696406007101	tetramer interface; other site
696406007102	dTDP-4-dehydrorhamnose reductase; Provisional; Region: PRK09987
696406007103	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
696406007104	NADP binding site [chemical binding]; other site
696406007105	active site
696406007106	putative substrate binding site [chemical binding]; other site
696406007107	dTDP-glucose 4,6 dehydratase; Provisional; Region: PRK10084
696406007108	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
696406007109	NAD binding site [chemical binding]; other site
696406007110	substrate binding site [chemical binding]; other site
696406007111	homodimer interface [polypeptide binding]; other site
696406007112	active site
696406007113	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
696406007114	active site
696406007115	tetramer interface; other site
696406007116	putative colanic acid biosynthesis protein; Provisional; Region: wcaM; PRK10123
696406007117	colanic acid biosynthesis glycosyltransferase WcaL; Region: wcaL; TIGR04005
696406007118	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
696406007119	putative ADP-binding pocket [chemical binding]; other site
696406007120	Polysaccharide pyruvyl transferase family protein [Cell wall/membrane/envelope biogenesis]; Region: WcaK; COG2327
696406007121	colanic acid biosynthesis pyruvyl transferase WcaK; Region: wcaK; TIGR04006
696406007122	colanic acid exporter; Provisional; Region: PRK10459
696406007123	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
696406007124	putative UDP-glucose lipid carrier transferase; Provisional; Region: PRK10124
696406007125	Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane]; Region: WcaJ; COG2148
696406007126	phosphomannomutase CpsG; Provisional; Region: PRK15414
696406007127	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
696406007128	active site
696406007129	substrate binding site [chemical binding]; other site
696406007130	metal binding site [ion binding]; metal-binding site
696406007131	mannose-1-phosphate guanyltransferase; Provisional; Region: cpsB; PRK15460
696406007132	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
696406007133	Substrate binding site; other site
696406007134	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
696406007135	colanic acid biosynthesis glycosyl transferase WcaI; Region: wcaI; TIGR04007
696406007136	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
696406007137	GDP-mannose glycosyl hydrolase (AKA GDP-mannose mannosyl hydrolase (GDPMH)) is a member of the Nudix hydrolase superfamily. This class of enzymes is unique from other members of the superfamily in two aspects. First, it contains a modified Nudix...; Region: GDPMH; cd03430
696406007138	active site
696406007139	GDP-Mannose binding site [chemical binding]; other site
696406007140	dimer interface [polypeptide binding]; other site
696406007141	modified nudix motif
696406007142	metal binding site [ion binding]; metal-binding site
696406007143	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
696406007144	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
696406007145	NADP binding site [chemical binding]; other site
696406007146	active site
696406007147	putative substrate binding site [chemical binding]; other site
696406007148	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
696406007149	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
696406007150	NADP-binding site; other site
696406007151	homotetramer interface [polypeptide binding]; other site
696406007152	substrate binding site [chemical binding]; other site
696406007153	homodimer interface [polypeptide binding]; other site
696406007154	active site
696406007155	colanic acid biosynthesis acetyltransferase WcaF; Region: WcaF; TIGR04008
696406007156	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
696406007157	putative trimer interface [polypeptide binding]; other site
696406007158	putative active site [active]
696406007159	putative substrate binding site [chemical binding]; other site
696406007160	putative CoA binding site [chemical binding]; other site
696406007161	putative glycosyl transferase; Provisional; Region: PRK10063
696406007162	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
696406007163	metal-binding site
696406007164	putative colanic acid polymerase WcaD; Region: WcaD; TIGR04010
696406007165	colanic acid biosynthesis glycosyl transferase WcaC; Region: WcaC; TIGR04015
696406007166	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
696406007167	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
696406007168	putative acyl transferase; Provisional; Region: PRK10191
696406007169	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
696406007170	trimer interface [polypeptide binding]; other site
696406007171	active site
696406007172	substrate binding site [chemical binding]; other site
696406007173	CoA binding site [chemical binding]; other site
696406007174	putative glycosyl transferase; Provisional; Region: PRK10018
696406007175	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
696406007176	active site
696406007177	tyrosine kinase; Provisional; Region: PRK11519
696406007178	Chain length determinant protein; Region: Wzz; pfam02706
696406007179	Chain length determinant protein; Region: Wzz; cl15801
696406007180	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
696406007181	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
696406007182	Low molecular weight phosphatase family; Region: LMWPc; cd00115
696406007183	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
696406007184	active site
696406007185	polysaccharide export protein Wza; Provisional; Region: PRK15078
696406007186	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
696406007187	SLBB domain; Region: SLBB; pfam10531
696406007188	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
696406007189	FOG: CBS domain [General function prediction only]; Region: COG0517
696406007190	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
696406007191	Transporter associated domain; Region: CorC_HlyC; smart01091
696406007192	putative assembly protein; Provisional; Region: PRK10833
696406007193	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
696406007194	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
696406007195	trimer interface [polypeptide binding]; other site
696406007196	active site
696406007197	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
696406007198	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
696406007199	ATP-binding site [chemical binding]; other site
696406007200	Sugar specificity; other site
696406007201	Pyrimidine base specificity; other site
696406007202	Predicted integral membrane sensor domain [Signal transduction mechanisms]; Region: COG3447
696406007203	putative diguanylate cyclase; Provisional; Region: PRK09776
696406007204	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
696406007205	putative active site [active]
696406007206	heme pocket [chemical binding]; other site
696406007207	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
696406007208	putative active site [active]
696406007209	heme pocket [chemical binding]; other site
696406007210	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
696406007211	putative active site [active]
696406007212	heme pocket [chemical binding]; other site
696406007213	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
696406007214	metal binding site [ion binding]; metal-binding site
696406007215	active site
696406007216	I-site; other site
696406007217	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
696406007218	3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308
696406007219	AlkA N-terminal domain; Region: AlkA_N; smart01009
696406007220	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
696406007221	minor groove reading motif; other site
696406007222	helix-hairpin-helix signature motif; other site
696406007223	substrate binding pocket [chemical binding]; other site
696406007224	active site
696406007225	putative chaperone; Provisional; Region: PRK11678
696406007226	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
696406007227	nucleotide binding site [chemical binding]; other site
696406007228	putative NEF/HSP70 interaction site [polypeptide binding]; other site
696406007229	SBD interface [polypeptide binding]; other site
696406007230	Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains [General function prediction only]; Region: COG4248
696406007231	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
696406007232	substrate binding site [chemical binding]; other site
696406007233	activation loop (A-loop); other site
696406007234	Y-family of DNA polymerases; Region: PolY; cl12025
696406007235	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3779
696406007236	Uncharacterized protein conserved in bacteria (DUF2314); Region: DUF2314; pfam10077
696406007237	Protein phosphatase 2C; Region: PP2C_2; pfam13672
696406007238	VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subfamily; cd01464
696406007239	metal ion-dependent adhesion site (MIDAS); other site
696406007240	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
696406007241	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
696406007242	HlyD family secretion protein; Region: HlyD_3; pfam13437
696406007243	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
696406007244	Protein export membrane protein; Region: SecD_SecF; cl14618
696406007245	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
696406007246	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
696406007247	putative transporter; Provisional; Region: PRK10504
696406007248	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406007249	putative substrate translocation pore; other site
696406007250	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406007251	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
696406007252	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
696406007253	dimerization interface [polypeptide binding]; other site
696406007254	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
696406007255	dimer interface [polypeptide binding]; other site
696406007256	phosphorylation site [posttranslational modification]
696406007257	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406007258	ATP binding site [chemical binding]; other site
696406007259	Mg2+ binding site [ion binding]; other site
696406007260	G-X-G motif; other site
696406007261	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
696406007262	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406007263	active site
696406007264	phosphorylation site [posttranslational modification]
696406007265	intermolecular recognition site; other site
696406007266	dimerization interface [polypeptide binding]; other site
696406007267	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
696406007268	DNA binding site [nucleotide binding]
696406007269	Uncharacterized conserved protein [Function unknown]; Region: COG3422
696406007270	Domain of unknown function (DUF1508); Region: DUF1508; pfam07411
696406007271	putative protease; Provisional; Region: PRK15452
696406007272	Peptidase family U32; Region: Peptidase_U32; pfam01136
696406007273	lipid kinase; Reviewed; Region: PRK13054
696406007274	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
696406007275	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
696406007276	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
696406007277	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696406007278	motif II; other site
696406007279	polyol permease family; Region: 2A0118; TIGR00897
696406007280	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406007281	putative substrate translocation pore; other site
696406007282	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
696406007283	N- and C-terminal domain interface [polypeptide binding]; other site
696406007284	D-xylulose kinase; Region: XylB; TIGR01312
696406007285	active site
696406007286	MgATP binding site [chemical binding]; other site
696406007287	catalytic site [active]
696406007288	metal binding site [ion binding]; metal-binding site
696406007289	xylulose binding site [chemical binding]; other site
696406007290	homodimer interface [polypeptide binding]; other site
696406007291	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
696406007292	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
696406007293	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
696406007294	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
696406007295	helix_turn_helix, cAMP Regulatory protein; Region: HTH_CRP; smart00419
696406007296	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
696406007297	Transcriptional regulators [Transcription]; Region: PurR; COG1609
696406007298	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
696406007299	DNA binding site [nucleotide binding]
696406007300	domain linker motif; other site
696406007301	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
696406007302	dimerization interface [polypeptide binding]; other site
696406007303	ligand binding site [chemical binding]; other site
696406007304	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
696406007305	classical (c) SDRs; Region: SDR_c; cd05233
696406007306	NAD(P) binding site [chemical binding]; other site
696406007307	active site
696406007308	Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_YpCarbK_like; cd07782
696406007309	FGGY-family pentulose kinase; Region: 5C_CHO_kinase; TIGR01315
696406007310	N- and C-terminal domain interface [polypeptide binding]; other site
696406007311	active site
696406007312	MgATP binding site [chemical binding]; other site
696406007313	catalytic site [active]
696406007314	metal binding site [ion binding]; metal-binding site
696406007315	carbohydrate binding site [chemical binding]; other site
696406007316	putative homodimer interface [polypeptide binding]; other site
696406007317	polyol permease family; Region: 2A0118; TIGR00897
696406007318	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406007319	putative substrate translocation pore; other site
696406007320	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
696406007321	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
696406007322	putative active site; other site
696406007323	catalytic residue [active]
696406007324	nucleoside transporter; Region: 2A0110; TIGR00889
696406007325	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406007326	putative substrate translocation pore; other site
696406007327	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
696406007328	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
696406007329	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
696406007330	substrate binding site [chemical binding]; other site
696406007331	ATP binding site [chemical binding]; other site
696406007332	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
696406007333	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
696406007334	DNA-binding site [nucleotide binding]; DNA binding site
696406007335	UTRA domain; Region: UTRA; pfam07702
696406007336	Lyzozyme M1 (1,4-beta-N-acetylmuramidase) [Cell envelope biogenesis, outer membrane]; Region: Acm; COG3757
696406007337	YegX is an uncharacterized bacterial protein with a glycosyl hydrolase family 25 (GH25) catalytic domain that is similar in sequence to the CH-type (Chalaropsis-type) lysozymes of the GH25 family of endolysins; Region: GH25_YegX-like; cd06524
696406007338	active site
696406007339	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
696406007340	dimer interface [polypeptide binding]; other site
696406007341	substrate binding site [chemical binding]; other site
696406007342	ATP binding site [chemical binding]; other site
696406007343	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
696406007344	substrate binding site [chemical binding]; other site
696406007345	multimerization interface [polypeptide binding]; other site
696406007346	ATP binding site [chemical binding]; other site
696406007347	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
696406007348	putative metal binding site [ion binding]; other site
696406007349	putative homodimer interface [polypeptide binding]; other site
696406007350	putative homotetramer interface [polypeptide binding]; other site
696406007351	putative homodimer-homodimer interface [polypeptide binding]; other site
696406007352	putative allosteric switch controlling residues; other site
696406007353	nickel/cobalt efflux protein RcnA; Provisional; Region: PRK10019
696406007354	Predicted integral membrane protein [Function unknown]; Region: COG5455
696406007355	putative fimbrial-like adhesin protein StcD; Provisional; Region: PRK15252
696406007356	putative fimbrial biosynthesis regulatory protein; Provisional; Region: PRK15216
696406007357	fimbrial outer membrane usher protein; Provisional; Region: PRK15217
696406007358	PapC N-terminal domain; Region: PapC_N; pfam13954
696406007359	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
696406007360	PapC C-terminal domain; Region: PapC_C; pfam13953
696406007361	putative fimbrial assembly chaperone protein StcB; Provisional; Region: PRK15253
696406007362	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
696406007363	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
696406007364	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
696406007365	Protein of unknown function (DUF2574); Region: DUF2574; pfam10836
696406007366	antiporter inner membrane protein; Provisional; Region: PRK11670
696406007367	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
696406007368	Walker A motif; other site
696406007369	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
696406007370	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
696406007371	active site
696406007372	HIGH motif; other site
696406007373	KMSKS motif; other site
696406007374	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
696406007375	tRNA binding surface [nucleotide binding]; other site
696406007376	anticodon binding site; other site
696406007377	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
696406007378	dimer interface [polypeptide binding]; other site
696406007379	putative tRNA-binding site [nucleotide binding]; other site
696406007380	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
696406007381	MoxR-like ATPases [General function prediction only]; Region: COG0714
696406007382	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406007383	Walker A motif; other site
696406007384	ATP binding site [chemical binding]; other site
696406007385	Walker B motif; other site
696406007386	arginine finger; other site
696406007387	VWA domain containing CoxE-like protein; Region: VWA_CoxE; pfam05762
696406007388	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
696406007389	metal ion-dependent adhesion site (MIDAS); other site
696406007390	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
696406007391	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
696406007392	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
696406007393	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
696406007394	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
696406007395	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406007396	active site
696406007397	phosphorylation site [posttranslational modification]
696406007398	intermolecular recognition site; other site
696406007399	dimerization interface [polypeptide binding]; other site
696406007400	LytTr DNA-binding domain; Region: LytTR; pfam04397
696406007401	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
696406007402	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
696406007403	GAF domain; Region: GAF; pfam01590
696406007404	Histidine kinase; Region: His_kinase; pfam06580
696406007405	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406007406	ATP binding site [chemical binding]; other site
696406007407	Mg2+ binding site [ion binding]; other site
696406007408	G-X-G motif; other site
696406007409	transcriptional regulator MirA; Provisional; Region: PRK15043
696406007410	Helix-Turn-Helix DNA binding domain of MlrA-like transcription regulators; Region: HTH_MlrA-like; cd04763
696406007411	DNA binding residues [nucleotide binding]
696406007412	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406007413	dimer interface [polypeptide binding]; other site
696406007414	conserved gate region; other site
696406007415	putative PBP binding loops; other site
696406007416	ABC-ATPase subunit interface; other site
696406007417	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
696406007418	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
696406007419	Walker A/P-loop; other site
696406007420	ATP binding site [chemical binding]; other site
696406007421	Q-loop/lid; other site
696406007422	ABC transporter signature motif; other site
696406007423	Walker B; other site
696406007424	D-loop; other site
696406007425	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
696406007426	H-loop/switch region; other site
696406007427	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406007428	dimer interface [polypeptide binding]; other site
696406007429	conserved gate region; other site
696406007430	ABC-ATPase subunit interface; other site
696406007431	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
696406007432	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
696406007433	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
696406007434	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
696406007435	D-lactate dehydrogenase; Provisional; Region: PRK11183
696406007436	FAD binding domain; Region: FAD_binding_4; pfam01565
696406007437	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
696406007438	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
696406007439	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
696406007440	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
696406007441	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
696406007442	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
696406007443	oxidoreductase; Provisional; Region: PRK12743
696406007444	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
696406007445	NAD(P) binding site [chemical binding]; other site
696406007446	active site
696406007447	multidrug resistance outer membrane protein MdtQ; Provisional; Region: PRK11459
696406007448	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
696406007449	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
696406007450	FMN binding site [chemical binding]; other site
696406007451	active site
696406007452	catalytic residues [active]
696406007453	substrate binding site [chemical binding]; other site
696406007454	hypothetical protein; Provisional; Region: PRK01821
696406007455	hypothetical protein; Provisional; Region: PRK10711
696406007456	cytidine deaminase; Provisional; Region: PRK09027
696406007457	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
696406007458	active site
696406007459	catalytic motif [active]
696406007460	Zn binding site [ion binding]; other site
696406007461	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
696406007462	active site
696406007463	catalytic motif [active]
696406007464	Zn binding site [ion binding]; other site
696406007465	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
696406007466	putative active site [active]
696406007467	Protein of unknown function (DUF2542); Region: DUF2542; pfam10808
696406007468	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
696406007469	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
696406007470	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
696406007471	dihydropyrimidine dehydrogenase subunit B; Validated; Region: PRK08318
696406007472	Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain.  DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and...; Region: DHPD_FMN; cd02940
696406007473	homodimer interface [polypeptide binding]; other site
696406007474	active site
696406007475	FMN binding site [chemical binding]; other site
696406007476	substrate binding site [chemical binding]; other site
696406007477	4Fe-4S binding domain; Region: Fer4; pfam00037
696406007478	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
696406007479	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
696406007480	TM-ABC transporter signature motif; other site
696406007481	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
696406007482	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
696406007483	Walker A/P-loop; other site
696406007484	ATP binding site [chemical binding]; other site
696406007485	Q-loop/lid; other site
696406007486	ABC transporter signature motif; other site
696406007487	Walker B; other site
696406007488	D-loop; other site
696406007489	H-loop/switch region; other site
696406007490	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
696406007491	methyl-galactoside ABC transporter galactose-binding periplasmic protein MglB; Provisional; Region: PRK15395
696406007492	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
696406007493	ligand binding site [chemical binding]; other site
696406007494	calcium binding site [ion binding]; other site
696406007495	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
696406007496	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
696406007497	DNA binding site [nucleotide binding]
696406007498	domain linker motif; other site
696406007499	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
696406007500	dimerization interface (closed form) [polypeptide binding]; other site
696406007501	ligand binding site [chemical binding]; other site
696406007502	Predicted membrane protein [Function unknown]; Region: COG2311
696406007503	hypothetical protein; Provisional; Region: PRK10835
696406007504	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
696406007505	homodecamer interface [polypeptide binding]; other site
696406007506	GTP cyclohydrolase I; Provisional; Region: PLN03044
696406007507	active site
696406007508	putative catalytic site residues [active]
696406007509	zinc binding site [ion binding]; other site
696406007510	GTP-CH-I/GFRP interaction surface; other site
696406007511	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
696406007512	S-formylglutathione hydrolase; Region: PLN02442
696406007513	catecholate siderophore receptor CirA; Provisional; Region: PRK10064
696406007514	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
696406007515	N-terminal plug; other site
696406007516	ligand-binding site [chemical binding]; other site
696406007517	lysine transporter; Provisional; Region: PRK10836
696406007518	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
696406007519	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406007520	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
696406007521	putative dimerization interface [polypeptide binding]; other site
696406007522	conserved hypothetical integral membrane protein; Region: TIGR00698
696406007523	endonuclease IV; Provisional; Region: PRK01060
696406007524	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
696406007525	AP (apurinic/apyrimidinic) site pocket; other site
696406007526	DNA interaction; other site
696406007527	Metal-binding active site; metal-binding site
696406007528	putative kinase; Provisional; Region: PRK09954
696406007529	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
696406007530	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
696406007531	substrate binding site [chemical binding]; other site
696406007532	ATP binding site [chemical binding]; other site
696406007533	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
696406007534	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
696406007535	Nucleoside recognition; Region: Gate; pfam07670
696406007536	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
696406007537	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
696406007538	active site
696406007539	tetramer interface [polypeptide binding]; other site
696406007540	DNA-binding transcriptional activator YeiL; Provisional; Region: PRK10402
696406007541	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
696406007542	ligand binding site [chemical binding]; other site
696406007543	flexible hinge region; other site
696406007544	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
696406007545	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
696406007546	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
696406007547	Nucleoside recognition; Region: Gate; pfam07670
696406007548	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
696406007549	Indigoidine synthase A like protein; Region: Indigoidine_A; pfam04227
696406007550	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
696406007551	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
696406007552	substrate binding site [chemical binding]; other site
696406007553	ATP binding site [chemical binding]; other site
696406007554	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
696406007555	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
696406007556	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
696406007557	active site
696406007558	P-loop; other site
696406007559	phosphorylation site [posttranslational modification]
696406007560	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
696406007561	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
696406007562	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
696406007563	putative substrate binding site [chemical binding]; other site
696406007564	putative ATP binding site [chemical binding]; other site
696406007565	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
696406007566	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
696406007567	active site
696406007568	phosphorylation site [posttranslational modification]
696406007569	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
696406007570	dimerization domain swap beta strand [polypeptide binding]; other site
696406007571	regulatory protein interface [polypeptide binding]; other site
696406007572	active site
696406007573	regulatory phosphorylation site [posttranslational modification]; other site
696406007574	sugar efflux transporter B; Provisional; Region: PRK15011
696406007575	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406007576	putative substrate translocation pore; other site
696406007577	elongation factor P; Provisional; Region: PRK04542
696406007578	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
696406007579	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
696406007580	RNA binding site [nucleotide binding]; other site
696406007581	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
696406007582	RNA binding site [nucleotide binding]; other site
696406007583	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
696406007584	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
696406007585	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
696406007586	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
696406007587	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
696406007588	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
696406007589	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
696406007590	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
696406007591	active site
696406007592	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
696406007593	NlpC/P60 family; Region: NLPC_P60; pfam00877
696406007594	phage resistance protein; Provisional; Region: PRK10551
696406007595	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
696406007596	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
696406007597	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
696406007598	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
696406007599	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
696406007600	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406007601	dimer interface [polypeptide binding]; other site
696406007602	conserved gate region; other site
696406007603	putative PBP binding loops; other site
696406007604	ABC-ATPase subunit interface; other site
696406007605	microcin C ABC transporter permease; Provisional; Region: PRK15021
696406007606	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406007607	dimer interface [polypeptide binding]; other site
696406007608	conserved gate region; other site
696406007609	ABC-ATPase subunit interface; other site
696406007610	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
696406007611	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
696406007612	Walker A/P-loop; other site
696406007613	ATP binding site [chemical binding]; other site
696406007614	Q-loop/lid; other site
696406007615	ABC transporter signature motif; other site
696406007616	Walker B; other site
696406007617	D-loop; other site
696406007618	H-loop/switch region; other site
696406007619	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
696406007620	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
696406007621	Walker A/P-loop; other site
696406007622	ATP binding site [chemical binding]; other site
696406007623	Q-loop/lid; other site
696406007624	ABC transporter signature motif; other site
696406007625	Walker B; other site
696406007626	D-loop; other site
696406007627	H-loop/switch region; other site
696406007628	hypothetical protein; Provisional; Region: PRK11835
696406007629	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406007630	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
696406007631	putative substrate translocation pore; other site
696406007632	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
696406007633	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
696406007634	RNA binding surface [nucleotide binding]; other site
696406007635	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
696406007636	active site
696406007637	uracil binding [chemical binding]; other site
696406007638	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
696406007639	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
696406007640	ATP binding site [chemical binding]; other site
696406007641	putative Mg++ binding site [ion binding]; other site
696406007642	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
696406007643	nucleotide binding region [chemical binding]; other site
696406007644	ATP-binding site [chemical binding]; other site
696406007645	Ribosomal L40e family; Region: Ribosomal_L40e; cl00671
696406007646	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
696406007647	5S rRNA interface [nucleotide binding]; other site
696406007648	CTC domain interface [polypeptide binding]; other site
696406007649	L16 interface [polypeptide binding]; other site
696406007650	Nucleoid-associated protein [General function prediction only]; Region: COG3081
696406007651	nucleoid-associated protein NdpA; Validated; Region: PRK00378
696406007652	hypothetical protein; Provisional; Region: PRK13689
696406007653	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
696406007654	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
696406007655	Sulfatase; Region: Sulfatase; pfam00884
696406007656	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
696406007657	hypothetical protein; Provisional; Region: PRK09945
696406007658	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
696406007659	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
696406007660	Autotransporter beta-domain; Region: Autotransporter; pfam03797
696406007661	transcriptional regulator NarP; Provisional; Region: PRK10403
696406007662	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406007663	active site
696406007664	phosphorylation site [posttranslational modification]
696406007665	intermolecular recognition site; other site
696406007666	dimerization interface [polypeptide binding]; other site
696406007667	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
696406007668	DNA binding residues [nucleotide binding]
696406007669	dimerization interface [polypeptide binding]; other site
696406007670	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
696406007671	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
696406007672	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
696406007673	binding surface
696406007674	TPR motif; other site
696406007675	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
696406007676	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
696406007677	catalytic residues [active]
696406007678	central insert; other site
696406007679	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
696406007680	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13165
696406007681	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
696406007682	heme exporter protein CcmC; Region: ccmC; TIGR01191
696406007683	heme exporter protein CcmB; Region: ccmB; TIGR01190
696406007684	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
696406007685	Cytochrome c biogenesis ATP-binding export protein; Region: ABC_CcmA_heme_exporter; cd03231
696406007686	Walker A/P-loop; other site
696406007687	ATP binding site [chemical binding]; other site
696406007688	Q-loop/lid; other site
696406007689	ABC transporter signature motif; other site
696406007690	Walker B; other site
696406007691	D-loop; other site
696406007692	H-loop/switch region; other site
696406007693	cytochrome c-type protein NapC; Provisional; Region: PRK10617
696406007694	Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit [Energy production and conversion]; Region: TorC; COG3005
696406007695	nitrate reductase cytochrome C550 subunit; Provisional; Region: napB; PRK11586
696406007696	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
696406007697	4Fe-4S binding domain; Region: Fer4_5; pfam12801
696406007698	4Fe-4S binding domain; Region: Fer4_6; pfam12837
696406007699	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
696406007700	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
696406007701	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
696406007702	[4Fe-4S] binding site [ion binding]; other site
696406007703	molybdopterin cofactor binding site; other site
696406007704	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
696406007705	molybdopterin cofactor binding site; other site
696406007706	assembly protein for periplasmic nitrate reductase; Provisional; Region: PRK10553
696406007707	ferredoxin-type protein; Provisional; Region: PRK10194
696406007708	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cd00242
696406007709	secondary substrate binding site; other site
696406007710	primary substrate binding site; other site
696406007711	inhibition loop; other site
696406007712	dimerization interface [polypeptide binding]; other site
696406007713	malate:quinone oxidoreductase; Validated; Region: PRK05257
696406007714	malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320
696406007715	multidrug transporter membrane component/ATP-binding component; Provisional; Region: PRK10522
696406007716	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
696406007717	Walker A/P-loop; other site
696406007718	ATP binding site [chemical binding]; other site
696406007719	Q-loop/lid; other site
696406007720	ABC transporter signature motif; other site
696406007721	Walker B; other site
696406007722	D-loop; other site
696406007723	H-loop/switch region; other site
696406007724	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
696406007725	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406007726	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
696406007727	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406007728	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
696406007729	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
696406007730	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
696406007731	DNA binding site [nucleotide binding]
696406007732	active site
696406007733	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
696406007734	ApbE family; Region: ApbE; pfam02424
696406007735	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
696406007736	outer membrane porin protein C; Provisional; Region: PRK10554
696406007737	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
696406007738	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406007739	ATP binding site [chemical binding]; other site
696406007740	G-X-G motif; other site
696406007741	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
696406007742	putative binding surface; other site
696406007743	active site
696406007744	transcriptional regulator RcsB; Provisional; Region: PRK10840
696406007745	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406007746	active site
696406007747	phosphorylation site [posttranslational modification]
696406007748	intermolecular recognition site; other site
696406007749	dimerization interface [polypeptide binding]; other site
696406007750	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
696406007751	DNA binding residues [nucleotide binding]
696406007752	dimerization interface [polypeptide binding]; other site
696406007753	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
696406007754	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
696406007755	dimer interface [polypeptide binding]; other site
696406007756	phosphorylation site [posttranslational modification]
696406007757	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406007758	ATP binding site [chemical binding]; other site
696406007759	Mg2+ binding site [ion binding]; other site
696406007760	G-X-G motif; other site
696406007761	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
696406007762	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406007763	active site
696406007764	phosphorylation site [posttranslational modification]
696406007765	intermolecular recognition site; other site
696406007766	dimerization interface [polypeptide binding]; other site
696406007767	sensory histidine kinase AtoS; Provisional; Region: PRK11360
696406007768	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
696406007769	putative active site [active]
696406007770	heme pocket [chemical binding]; other site
696406007771	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
696406007772	dimer interface [polypeptide binding]; other site
696406007773	phosphorylation site [posttranslational modification]
696406007774	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406007775	ATP binding site [chemical binding]; other site
696406007776	Mg2+ binding site [ion binding]; other site
696406007777	G-X-G motif; other site
696406007778	acetoacetate metabolism regulatory protein AtoC; Provisional; Region: PRK11361
696406007779	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406007780	active site
696406007781	phosphorylation site [posttranslational modification]
696406007782	intermolecular recognition site; other site
696406007783	dimerization interface [polypeptide binding]; other site
696406007784	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406007785	Walker A motif; other site
696406007786	ATP binding site [chemical binding]; other site
696406007787	Walker B motif; other site
696406007788	arginine finger; other site
696406007789	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
696406007790	acetyl-CoA:acetoacetyl-CoA transferase subunit alpha; Provisional; Region: PRK09920
696406007791	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
696406007792	Short chain fatty acid transporter; Region: SCFA_trans; pfam02667
696406007793	putative acyltransferase; Provisional; Region: PRK05790
696406007794	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
696406007795	dimer interface [polypeptide binding]; other site
696406007796	active site
696406007797	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4676
696406007798	Uncharacterized protein conserved in bacteria (DUF2135); Region: DUF2135; pfam09906
696406007799	Predicted secreted protein [Function unknown]; Region: COG5445
696406007800	Predicted secreted protein (DUF2300); Region: DUF2300; pfam10062
696406007801	Predicted secreted protein [Function unknown]; Region: COG5445
696406007802	Stage II sporulation protein; Region: SpoIID; pfam08486
696406007803	Predicted secreted protein (DUF2300); Region: DUF2300; pfam10062
696406007804	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
696406007805	MG2 domain; Region: A2M_N; pfam01835
696406007806	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cl17457
696406007807	Alpha-2-macroglobulin family; Region: A2M; pfam00207
696406007808	This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate...; Region: ISOPREN_C2_like; cl08267
696406007809	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4685
696406007810	DNA gyrase subunit A; Validated; Region: PRK05560
696406007811	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
696406007812	CAP-like domain; other site
696406007813	active site
696406007814	primary dimer interface [polypeptide binding]; other site
696406007815	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
696406007816	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
696406007817	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
696406007818	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
696406007819	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
696406007820	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
696406007821	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
696406007822	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406007823	S-adenosylmethionine binding site [chemical binding]; other site
696406007824	adhesin; Provisional; Region: PRK09752
696406007825	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
696406007826	Autotransporter beta-domain; Region: Autotransporter; pfam03797
696406007827	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
696406007828	ATP cone domain; Region: ATP-cone; pfam03477
696406007829	Class I ribonucleotide reductase; Region: RNR_I; cd01679
696406007830	active site
696406007831	dimer interface [polypeptide binding]; other site
696406007832	catalytic residues [active]
696406007833	effector binding site; other site
696406007834	R2 peptide binding site; other site
696406007835	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
696406007836	dimer interface [polypeptide binding]; other site
696406007837	putative radical transfer pathway; other site
696406007838	diiron center [ion binding]; other site
696406007839	tyrosyl radical; other site
696406007840	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
696406007841	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
696406007842	catalytic loop [active]
696406007843	iron binding site [ion binding]; other site
696406007844	hypothetical protein; Provisional; Region: PRK09902
696406007845	hypothetical protein; Provisional; Region: PRK09729
696406007846	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
696406007847	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
696406007848	active site
696406007849	catalytic site [active]
696406007850	metal binding site [ion binding]; metal-binding site
696406007851	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
696406007852	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406007853	putative substrate translocation pore; other site
696406007854	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
696406007855	hydroxyglutarate oxidase; Provisional; Region: PRK11728
696406007856	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
696406007857	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; COG3075
696406007858	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
696406007859	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
696406007860	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
696406007861	Cysteine-rich domain; Region: CCG; pfam02754
696406007862	Cysteine-rich domain; Region: CCG; pfam02754
696406007863	hypothetical protein; Provisional; Region: PRK09956
696406007864	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
696406007865	hypothetical protein; Provisional; Region: PRK09956
696406007866	2-keto-3-deoxy-L-rhamnonate aldolase; Provisional; Region: PRK10128
696406007867	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
696406007868	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406007869	putative substrate translocation pore; other site
696406007870	L-rhamnonate dehydratase; Provisional; Region: PRK15440
696406007871	Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 2. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic...; Region: MR_like_2; cd03327
696406007872	putative active site pocket [active]
696406007873	putative metal binding site [ion binding]; other site
696406007874	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
696406007875	Transcriptional regulator [Transcription]; Region: IclR; COG1414
696406007876	Bacterial transcriptional regulator; Region: IclR; pfam01614
696406007877	hypothetical protein; Provisional; Region: PRK03673
696406007878	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
696406007879	putative MPT binding site; other site
696406007880	Competence-damaged protein; Region: CinA; cl00666
696406007881	YfaZ precursor; Region: YfaZ; pfam07437
696406007882	outer membrane protein; Region: OMP_w_GlyGly; TIGR04219
696406007883	nucleoside triphosphatase NudI; Provisional; Region: PRK15472
696406007884	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
696406007885	catalytic core [active]
696406007886	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
696406007887	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
696406007888	inhibitor-cofactor binding pocket; inhibition site
696406007889	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406007890	catalytic residue [active]
696406007891	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
696406007892	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
696406007893	Ligand binding site; other site
696406007894	Putative Catalytic site; other site
696406007895	DXD motif; other site
696406007896	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
696406007897	ArnA, N-terminal formyltransferase domain; Region: FMT_core_ArnA_N; cd08644
696406007898	substrate binding site [chemical binding]; other site
696406007899	cosubstrate binding site; other site
696406007900	catalytic site [active]
696406007901	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
696406007902	active site
696406007903	hexamer interface [polypeptide binding]; other site
696406007904	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
696406007905	NAD binding site [chemical binding]; other site
696406007906	substrate binding site [chemical binding]; other site
696406007907	active site
696406007908	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
696406007909	Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939
696406007910	putative active site [active]
696406007911	putative catalytic site [active]
696406007912	putative Zn binding site [ion binding]; other site
696406007913	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
696406007914	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
696406007915	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
696406007916	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
696406007917	signal transduction protein PmrD; Provisional; Region: PRK15450
696406007918	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
696406007919	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
696406007920	acyl-activating enzyme (AAE) consensus motif; other site
696406007921	putative AMP binding site [chemical binding]; other site
696406007922	putative active site [active]
696406007923	putative CoA binding site [chemical binding]; other site
696406007924	O-succinylbenzoate synthase; Provisional; Region: PRK05105
696406007925	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
696406007926	active site
696406007927	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
696406007928	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
696406007929	substrate binding site [chemical binding]; other site
696406007930	oxyanion hole (OAH) forming residues; other site
696406007931	trimer interface [polypeptide binding]; other site
696406007932	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
696406007933	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
696406007934	nucleophilic elbow; other site
696406007935	catalytic triad; other site
696406007936	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
696406007937	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
696406007938	dimer interface [polypeptide binding]; other site
696406007939	tetramer interface [polypeptide binding]; other site
696406007940	PYR/PP interface [polypeptide binding]; other site
696406007941	TPP binding site [chemical binding]; other site
696406007942	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
696406007943	TPP-binding site; other site
696406007944	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
696406007945	isochorismate synthases; Region: isochor_syn; TIGR00543
696406007946	hypothetical protein; Provisional; Region: PRK10404
696406007947	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
696406007948	Coenzyme A binding pocket [chemical binding]; other site
696406007949	ribonuclease BN; Region: true_RNase_BN; TIGR02649
696406007950	deubiquitinase; Provisional; Region: PRK11836
696406007951	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
696406007952	Domain of unknown function (DUF1877); Region: DUF1877; pfam08974
696406007953	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
696406007954	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
696406007955	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
696406007956	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
696406007957	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
696406007958	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
696406007959	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
696406007960	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
696406007961	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
696406007962	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
696406007963	4Fe-4S binding domain; Region: Fer4; pfam00037
696406007964	4Fe-4S binding domain; Region: Fer4; pfam00037
696406007965	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
696406007966	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
696406007967	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
696406007968	catalytic loop [active]
696406007969	iron binding site [ion binding]; other site
696406007970	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
696406007971	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
696406007972	[4Fe-4S] binding site [ion binding]; other site
696406007973	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
696406007974	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
696406007975	SLBB domain; Region: SLBB; pfam10531
696406007976	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
696406007977	NADH dehydrogenase subunit E; Validated; Region: PRK07539
696406007978	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
696406007979	putative dimer interface [polypeptide binding]; other site
696406007980	[2Fe-2S] cluster binding site [ion binding]; other site
696406007981	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
696406007982	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
696406007983	NADH dehydrogenase subunit D; Validated; Region: PRK06075
696406007984	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
696406007985	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
696406007986	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
696406007987	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406007988	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
696406007989	putative dimerization interface [polypeptide binding]; other site
696406007990	aminotransferase AlaT; Validated; Region: PRK09265
696406007991	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
696406007992	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406007993	homodimer interface [polypeptide binding]; other site
696406007994	catalytic residue [active]
696406007995	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
696406007996	Zn2+ binding site [ion binding]; other site
696406007997	Mg2+ binding site [ion binding]; other site
696406007998	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
696406007999	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
696406008000	TrkA-C domain; Region: TrkA_C; pfam02080
696406008001	TrkA-C domain; Region: TrkA_C; pfam02080
696406008002	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
696406008003	putative phosphatase; Provisional; Region: PRK11587
696406008004	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696406008005	motif II; other site
696406008006	hypothetical protein; Validated; Region: PRK05445
696406008007	hypothetical protein; Provisional; Region: PRK01816
696406008008	propionate/acetate kinase; Provisional; Region: PRK12379
696406008009	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
696406008010	phosphate acetyltransferase; Reviewed; Region: PRK05632
696406008011	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
696406008012	DRTGG domain; Region: DRTGG; pfam07085
696406008013	phosphate acetyltransferase; Region: pta; TIGR00651
696406008014	hypothetical protein; Provisional; Region: PRK11588
696406008015	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
696406008016	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
696406008017	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
696406008018	nudix motif; other site
696406008019	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
696406008020	active site
696406008021	metal binding site [ion binding]; metal-binding site
696406008022	homotetramer interface [polypeptide binding]; other site
696406008023	glutathione S-transferase; Provisional; Region: PRK15113
696406008024	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
696406008025	C-terminal domain interface [polypeptide binding]; other site
696406008026	GSH binding site (G-site) [chemical binding]; other site
696406008027	dimer interface [polypeptide binding]; other site
696406008028	C-terminal, alpha helical domain of an unknown subfamily 4 of Glutathione S-transferases; Region: GST_C_4; cd03195
696406008029	N-terminal domain interface [polypeptide binding]; other site
696406008030	putative dimer interface [polypeptide binding]; other site
696406008031	putative substrate binding pocket (H-site) [chemical binding]; other site
696406008032	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
696406008033	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
696406008034	C-terminal domain interface [polypeptide binding]; other site
696406008035	GSH binding site (G-site) [chemical binding]; other site
696406008036	dimer interface [polypeptide binding]; other site
696406008037	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
696406008038	N-terminal domain interface [polypeptide binding]; other site
696406008039	putative dimer interface [polypeptide binding]; other site
696406008040	active site
696406008041	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
696406008042	homooctamer interface [polypeptide binding]; other site
696406008043	active site
696406008044	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
696406008045	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
696406008046	putative NAD(P) binding site [chemical binding]; other site
696406008047	putative active site [active]
696406008048	putative transposase; Provisional; Region: PRK09857
696406008049	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
696406008050	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
696406008051	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
696406008052	Walker A/P-loop; other site
696406008053	ATP binding site [chemical binding]; other site
696406008054	Q-loop/lid; other site
696406008055	ABC transporter signature motif; other site
696406008056	Walker B; other site
696406008057	D-loop; other site
696406008058	H-loop/switch region; other site
696406008059	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406008060	dimer interface [polypeptide binding]; other site
696406008061	conserved gate region; other site
696406008062	putative PBP binding loops; other site
696406008063	ABC-ATPase subunit interface; other site
696406008064	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
696406008065	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406008066	dimer interface [polypeptide binding]; other site
696406008067	conserved gate region; other site
696406008068	putative PBP binding loops; other site
696406008069	ABC-ATPase subunit interface; other site
696406008070	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
696406008071	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
696406008072	substrate binding pocket [chemical binding]; other site
696406008073	membrane-bound complex binding site; other site
696406008074	hinge residues; other site
696406008075	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
696406008076	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
696406008077	substrate binding pocket [chemical binding]; other site
696406008078	membrane-bound complex binding site; other site
696406008079	hinge residues; other site
696406008080	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
696406008081	Flavoprotein; Region: Flavoprotein; pfam02441
696406008082	amidophosphoribosyltransferase; Provisional; Region: PRK09246
696406008083	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
696406008084	active site
696406008085	tetramer interface [polypeptide binding]; other site
696406008086	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
696406008087	active site
696406008088	colicin V production protein; Provisional; Region: PRK10845
696406008089	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
696406008090	cell division protein DedD; Provisional; Region: PRK11633
696406008091	Sporulation related domain; Region: SPOR; pfam05036
696406008092	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
696406008093	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
696406008094	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
696406008095	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
696406008096	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
696406008097	hypothetical protein; Provisional; Region: PRK10847
696406008098	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
696406008099	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
696406008100	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
696406008101	dimerization interface 3.5A [polypeptide binding]; other site
696406008102	active site
696406008103	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
696406008104	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
696406008105	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
696406008106	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
696406008107	ligand binding site [chemical binding]; other site
696406008108	NAD binding site [chemical binding]; other site
696406008109	catalytic site [active]
696406008110	homodimer interface [polypeptide binding]; other site
696406008111	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
696406008112	putative transporter; Provisional; Region: PRK12382
696406008113	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406008114	putative substrate translocation pore; other site
696406008115	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
696406008116	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
696406008117	dimer interface [polypeptide binding]; other site
696406008118	active site
696406008119	Uncharacterized conserved protein [Function unknown]; Region: COG4121
696406008120	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
696406008121	YfcL protein; Region: YfcL; pfam08891
696406008122	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3101
696406008123	hypothetical protein; Provisional; Region: PRK10621
696406008124	Predicted permeases [General function prediction only]; Region: COG0730
696406008125	Murein endopeptidase [Cell envelope biogenesis, outer membrane]; Region: MepA; COG3770
696406008126	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
696406008127	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
696406008128	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
696406008129	Tetramer interface [polypeptide binding]; other site
696406008130	active site
696406008131	FMN-binding site [chemical binding]; other site
696406008132	HemK family putative methylases; Region: hemK_fam; TIGR00536
696406008133	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406008134	S-adenosylmethionine binding site [chemical binding]; other site
696406008135	hypothetical protein; Provisional; Region: PRK04946
696406008136	Smr domain; Region: Smr; pfam01713
696406008137	Protein of unknown function (DUF2544); Region: DUF2544; pfam11245
696406008138	Fimbrial protein; Region: Fimbrial; cl01416
696406008139	Fimbrial protein; Region: Fimbrial; cl01416
696406008140	Fimbrial protein; Region: Fimbrial; cl01416
696406008141	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
696406008142	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
696406008143	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
696406008144	PapC N-terminal domain; Region: PapC_N; pfam13954
696406008145	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
696406008146	PapC C-terminal domain; Region: PapC_C; pfam13953
696406008147	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
696406008148	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
696406008149	catalytic core [active]
696406008150	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
696406008151	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
696406008152	substrate binding site [chemical binding]; other site
696406008153	oxyanion hole (OAH) forming residues; other site
696406008154	trimer interface [polypeptide binding]; other site
696406008155	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
696406008156	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
696406008157	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
696406008158	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
696406008159	dimer interface [polypeptide binding]; other site
696406008160	active site
696406008161	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
696406008162	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
696406008163	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
696406008164	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
696406008165	integrase; Provisional; Region: PRK09692
696406008166	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
696406008167	active site
696406008168	Int/Topo IB signature motif; other site
696406008169	Head binding; Region: Head_binding; pfam09008
696406008170	P22_AR N-terminal domain; Region: P22_AR_N; pfam10547
696406008171	Phage anti-repressor protein [Transcription]; Region: COG3561
696406008172	Protein of unknown function (DUF4065); Region: DUF4065; pfam13274
696406008173	Protein of unknown function (DUF2824); Region: DUF2824; pfam11039
696406008174	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
696406008175	Phage stabilisation protein; Region: Phage_stabilise; pfam11134
696406008176	P22 tail accessory factor; Region: P22_Tail-4; pfam11650
696406008177	P22 coat protein - gene protein 5; Region: P22_CoatProtein; pfam11651
696406008178	putative transposase OrfB; Reviewed; Region: PHA02517
696406008179	HTH-like domain; Region: HTH_21; pfam13276
696406008180	Integrase core domain; Region: rve; pfam00665
696406008181	Integrase core domain; Region: rve_3; pfam13683
696406008182	Transposase; Region: HTH_Tnp_1; cl17663
696406008183	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
696406008184	Terminase-like family; Region: Terminase_6; pfam03237
696406008185	Bacteriophage terminase large (ATPase) subunit and inactivated derivatives [General function prediction only]; Region: COG5565
696406008186	Protein of unknown function (DUF2560); Region: DUF2560; pfam10834
696406008187	hypothetical protein; Region: PHA01971
696406008188	Protein of unknown function (DUF2829); Region: DUF2829; pfam11195
696406008189	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
696406008190	The lysozyme from bacteriophage lambda hydrolyses the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc), as do other lysozymes.  But unlike other lysozymes, bacteriophage lambda does not produce a reducing...; Region: bacteriophage_lambda_lysozyme; cd00736
696406008191	N-acetyl-D-glucosamine binding site [chemical binding]; other site
696406008192	catalytic residue [active]
696406008193	phage holin, lambda family; Region: holin_lambda; TIGR01594
696406008194	Antitermination protein; Region: Antiterm; pfam03589
696406008195	Antitermination protein; Region: Antiterm; pfam03589
696406008196	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
696406008197	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
696406008198	active site
696406008199	metal binding site [ion binding]; metal-binding site
696406008200	Phage NinH protein; Region: Phage_NinH; pfam06322
696406008201	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
696406008202	Protein of unknown function (DUF2591); Region: DUF2591; pfam10765
696406008203	phage N-6-adenine-methyltransferase; Region: phage_N6A_met; TIGR01712
696406008204	NinB protein; Region: NinB; pfam05772
696406008205	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
696406008206	DnaB-like helicase C terminal domain; Region: DnaB_C; pfam03796
696406008207	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
696406008208	Walker A motif; other site
696406008209	ATP binding site [chemical binding]; other site
696406008210	Walker B motif; other site
696406008211	DNA binding loops [nucleotide binding]
696406008212	Bacteriophage replication protein O; Region: Phage_rep_O; cl04545
696406008213	Bacteriophage CII protein; Region: Phage_CII; pfam05269
696406008214	Cro; Region: Cro; pfam09048
696406008215	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
696406008216	non-specific DNA binding site [nucleotide binding]; other site
696406008217	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
696406008218	salt bridge; other site
696406008219	sequence-specific DNA binding site [nucleotide binding]; other site
696406008220	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
696406008221	Catalytic site [active]
696406008222	Caseinolytic protease (ClpP) is an ATP-dependent protease; Region: Clp_protease_like; cl15763
696406008223	active site
696406008224	Bacteriophage lambda Kil protein; Region: Lambda_Kil; pfam06301
696406008225	ERF superfamily; Region: ERF; pfam04404
696406008226	Protein of unknown function (DUF2856); Region: DUF2856; pfam11043
696406008227	Protein of unknown function (DUF2737); Region: DUF2737; pfam10930
696406008228	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
696406008229	ASC-1 homology or ASCH domain, a small beta-barrel domain found in all three kingdoms of life. ASCH resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as an RNA-binding domain during coactivation; Region: ASCH; cl01020
696406008230	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523
696406008231	DNA-binding transcriptional regulator DsdC; Provisional; Region: PRK10086
696406008232	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406008233	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
696406008234	dimerization interface [polypeptide binding]; other site
696406008235	substrate binding pocket [chemical binding]; other site
696406008236	permease DsdX; Provisional; Region: PRK09921
696406008237	gluconate transporter; Region: gntP; TIGR00791
696406008238	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
696406008239	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
696406008240	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
696406008241	catalytic residue [active]
696406008242	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
696406008243	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406008244	putative substrate translocation pore; other site
696406008245	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406008246	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
696406008247	HlyD family secretion protein; Region: HlyD_3; pfam13437
696406008248	DNA-binding transcriptional activator EvgA; Provisional; Region: PRK09958
696406008249	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406008250	active site
696406008251	phosphorylation site [posttranslational modification]
696406008252	intermolecular recognition site; other site
696406008253	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
696406008254	DNA binding residues [nucleotide binding]
696406008255	dimerization interface [polypeptide binding]; other site
696406008256	hybrid sensory histidine kinase in two-component regulatory system with EvgA; Provisional; Region: PRK09959
696406008257	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
696406008258	substrate binding pocket [chemical binding]; other site
696406008259	membrane-bound complex binding site; other site
696406008260	hinge residues; other site
696406008261	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
696406008262	substrate binding pocket [chemical binding]; other site
696406008263	membrane-bound complex binding site; other site
696406008264	hinge residues; other site
696406008265	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
696406008266	dimer interface [polypeptide binding]; other site
696406008267	phosphorylation site [posttranslational modification]
696406008268	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406008269	ATP binding site [chemical binding]; other site
696406008270	Mg2+ binding site [ion binding]; other site
696406008271	G-X-G motif; other site
696406008272	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406008273	active site
696406008274	phosphorylation site [posttranslational modification]
696406008275	intermolecular recognition site; other site
696406008276	dimerization interface [polypeptide binding]; other site
696406008277	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
696406008278	putative binding surface; other site
696406008279	active site
696406008280	putative CoA-transferase; Provisional; Region: PRK11430
696406008281	CoA-transferase family III; Region: CoA_transf_3; pfam02515
696406008282	putative transporter YfdV; Provisional; Region: PRK09903
696406008283	putative oxalyl-CoA decarboxylase; Validated; Region: PRK09259
696406008284	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
696406008285	PYR/PP interface [polypeptide binding]; other site
696406008286	dimer interface [polypeptide binding]; other site
696406008287	TPP binding site [chemical binding]; other site
696406008288	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
696406008289	Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of proteins similar to benzaldehyde lyase (BZL), oxalyl-CoA decarboxylase (OCoD) and 2-hydroxyphytanoyl-CoA lyase (2-HPCL). Pseudomonas fluorescens biovar I BZL...; Region: TPP_BZL_OCoD_HPCL; cd02004
696406008290	TPP-binding site; other site
696406008291	dimer interface [polypeptide binding]; other site
696406008292	formyl-coenzyme A transferase; Provisional; Region: PRK05398
696406008293	CoA-transferase family III; Region: CoA_transf_3; pfam02515
696406008294	hypothetical protein; Provisional; Region: PRK10316
696406008295	YfdX protein; Region: YfdX; pfam10938
696406008296	Protein of unknown function (DUF2545); Region: DUF2545; pfam10810
696406008297	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
696406008298	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
696406008299	putative acyl-acceptor binding pocket; other site
696406008300	aminotransferase; Validated; Region: PRK08175
696406008301	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
696406008302	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406008303	homodimer interface [polypeptide binding]; other site
696406008304	catalytic residue [active]
696406008305	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
696406008306	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
696406008307	GAF domain; Region: GAF; pfam01590
696406008308	Histidine kinase; Region: His_kinase; pfam06580
696406008309	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406008310	ATP binding site [chemical binding]; other site
696406008311	Mg2+ binding site [ion binding]; other site
696406008312	G-X-G motif; other site
696406008313	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
696406008314	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406008315	active site
696406008316	phosphorylation site [posttranslational modification]
696406008317	intermolecular recognition site; other site
696406008318	dimerization interface [polypeptide binding]; other site
696406008319	LytTr DNA-binding domain; Region: LytTR; pfam04397
696406008320	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
696406008321	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406008322	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
696406008323	dimerization domain swap beta strand [polypeptide binding]; other site
696406008324	regulatory protein interface [polypeptide binding]; other site
696406008325	active site
696406008326	regulatory phosphorylation site [posttranslational modification]; other site
696406008327	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
696406008328	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
696406008329	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
696406008330	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
696406008331	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
696406008332	active site
696406008333	phosphorylation site [posttranslational modification]
696406008334	exoaminopeptidase; Provisional; Region: PRK09961
696406008335	M42 Peptidases, also known as glutamyl aminopeptidase family; Region: M42; cd05638
696406008336	oligomer interface [polypeptide binding]; other site
696406008337	active site
696406008338	metal binding site [ion binding]; metal-binding site
696406008339	aminopeptidase; Provisional; Region: PRK09795
696406008340	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
696406008341	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
696406008342	active site
696406008343	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
696406008344	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
696406008345	active site
696406008346	P-loop; other site
696406008347	phosphorylation site [posttranslational modification]
696406008348	glucokinase, proteobacterial type; Region: glk; TIGR00749
696406008349	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
696406008350	nucleotide binding site [chemical binding]; other site
696406008351	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
696406008352	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
696406008353	Cl- selectivity filter; other site
696406008354	Cl- binding residues [ion binding]; other site
696406008355	pore gating glutamate residue; other site
696406008356	dimer interface [polypeptide binding]; other site
696406008357	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
696406008358	manganese transport protein MntH; Reviewed; Region: PRK00701
696406008359	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
696406008360	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
696406008361	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
696406008362	Nucleoside recognition; Region: Gate; pfam07670
696406008363	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
696406008364	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
696406008365	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
696406008366	MASE1; Region: MASE1; pfam05231
696406008367	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
696406008368	diguanylate cyclase; Region: GGDEF; smart00267
696406008369	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
696406008370	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
696406008371	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
696406008372	salt bridge; other site
696406008373	non-specific DNA binding site [nucleotide binding]; other site
696406008374	sequence-specific DNA binding site [nucleotide binding]; other site
696406008375	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
696406008376	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
696406008377	active site
696406008378	HIGH motif; other site
696406008379	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
696406008380	active site
696406008381	KMSKS motif; other site
696406008382	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
696406008383	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406008384	The C-terminal substrate binding domain of LysR-type transcriptional regulator XapR involved in xanthosine catabolism, contains the type 2 periplasmic binding fold; Region: PBP2_XapR; cd08449
696406008385	putative dimerization interface [polypeptide binding]; other site
696406008386	putative substrate binding pocket [chemical binding]; other site
696406008387	XapX domain; Region: XapX; TIGR03510
696406008388	nucleoside transporter; Region: 2A0110; TIGR00889
696406008389	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406008390	putative substrate translocation pore; other site
696406008391	purine nucleoside phosphorylase; Provisional; Region: PRK08202
696406008392	hypothetical protein; Provisional; Region: PRK11528
696406008393	Transcriptional regulator [Transcription]; Region: LysR; COG0583
696406008394	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406008395	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
696406008396	putative dimerization interface [polypeptide binding]; other site
696406008397	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
696406008398	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
696406008399	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3530
696406008400	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
696406008401	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
696406008402	nucleotide binding pocket [chemical binding]; other site
696406008403	K-X-D-G motif; other site
696406008404	catalytic site [active]
696406008405	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
696406008406	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
696406008407	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
696406008408	Dimer interface [polypeptide binding]; other site
696406008409	BRCT sequence motif; other site
696406008410	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cl12038
696406008411	cell division protein ZipA; Provisional; Region: PRK03427
696406008412	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
696406008413	FtsZ protein binding site [polypeptide binding]; other site
696406008414	putative sulfate transport protein CysZ; Validated; Region: PRK04949
696406008415	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
696406008416	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
696406008417	dimer interface [polypeptide binding]; other site
696406008418	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406008419	catalytic residue [active]
696406008420	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
696406008421	dimerization domain swap beta strand [polypeptide binding]; other site
696406008422	regulatory protein interface [polypeptide binding]; other site
696406008423	active site
696406008424	regulatory phosphorylation site [posttranslational modification]; other site
696406008425	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
696406008426	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
696406008427	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
696406008428	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
696406008429	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
696406008430	HPr interaction site; other site
696406008431	glycerol kinase (GK) interaction site [polypeptide binding]; other site
696406008432	active site
696406008433	phosphorylation site [posttranslational modification]
696406008434	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
696406008435	dimer interface [polypeptide binding]; other site
696406008436	pyridoxamine kinase; Validated; Region: PRK05756
696406008437	pyridoxal binding site [chemical binding]; other site
696406008438	ATP binding site [chemical binding]; other site
696406008439	hypothetical protein; Provisional; Region: PRK10318
696406008440	WGR domain of molybdate metabolism regulator and related proteins; Region: WGR_MMR_like; cd07996
696406008441	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4884
696406008442	cysteine synthase B; Region: cysM; TIGR01138
696406008443	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
696406008444	dimer interface [polypeptide binding]; other site
696406008445	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406008446	catalytic residue [active]
696406008447	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
696406008448	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
696406008449	Walker A/P-loop; other site
696406008450	ATP binding site [chemical binding]; other site
696406008451	Q-loop/lid; other site
696406008452	ABC transporter signature motif; other site
696406008453	Walker B; other site
696406008454	D-loop; other site
696406008455	H-loop/switch region; other site
696406008456	TOBE-like domain; Region: TOBE_3; pfam12857
696406008457	sulfate transport protein; Provisional; Region: cysT; CHL00187
696406008458	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406008459	dimer interface [polypeptide binding]; other site
696406008460	conserved gate region; other site
696406008461	putative PBP binding loops; other site
696406008462	ABC-ATPase subunit interface; other site
696406008463	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
696406008464	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406008465	dimer interface [polypeptide binding]; other site
696406008466	conserved gate region; other site
696406008467	putative PBP binding loops; other site
696406008468	ABC-ATPase subunit interface; other site
696406008469	thiosulfate transporter subunit; Provisional; Region: PRK10852
696406008470	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
696406008471	short chain dehydrogenase; Provisional; Region: PRK08226
696406008472	human DHRS6-like, classical (c) SDRs; Region: DHRS6_like_SDR_c; cd05368
696406008473	NAD binding site [chemical binding]; other site
696406008474	homotetramer interface [polypeptide binding]; other site
696406008475	homodimer interface [polypeptide binding]; other site
696406008476	active site
696406008477	transcriptional regulator MurR; Provisional; Region: PRK15482
696406008478	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
696406008479	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
696406008480	putative active site [active]
696406008481	N-acetylmuramic acid 6-phosphate etherase; Region: TIGR00274
696406008482	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
696406008483	putative active site [active]
696406008484	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
696406008485	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
696406008486	active site turn [active]
696406008487	phosphorylation site [posttranslational modification]
696406008488	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
696406008489	putative periplasmic esterase; Provisional; Region: PRK03642
696406008490	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
696406008491	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
696406008492	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
696406008493	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
696406008494	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
696406008495	putative acetyltransferase; Provisional; Region: PRK03624
696406008496	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
696406008497	Coenzyme A binding pocket [chemical binding]; other site
696406008498	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
696406008499	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
696406008500	active site
696406008501	metal binding site [ion binding]; metal-binding site
696406008502	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
696406008503	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
696406008504	transcriptional regulator EutR; Provisional; Region: PRK10130
696406008505	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406008506	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406008507	carboxysome structural protein EutK; Provisional; Region: PRK15466
696406008508	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
696406008509	Hexamer interface [polypeptide binding]; other site
696406008510	Hexagonal pore residue; other site
696406008511	ethanolamine utilization protein EutL; Provisional; Region: PRK15405
696406008512	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_EutL_repeat1; cd07049
696406008513	putative hexamer interface [polypeptide binding]; other site
696406008514	putative hexagonal pore; other site
696406008515	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_EutL_repeat2; cd07050
696406008516	putative hexamer interface [polypeptide binding]; other site
696406008517	putative hexagonal pore; other site
696406008518	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
696406008519	Ethanolamine ammonia-lyase, large subunit [Amino acid transport and metabolism]; Region: EutB; COG4303
696406008520	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
696406008521	reactivating factor for ethanolamine ammonia lyase; Provisional; Region: eutA; PRK10719
696406008522	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutH; COG3192
696406008523	ethanol dehydrogenase EutG; Provisional; Region: PRK15454
696406008524	iron-containing alcohol dehydrogenases (Fe-ADH)-like; Region: Fe-ADH; cd08551
696406008525	active site
696406008526	metal binding site [ion binding]; metal-binding site
696406008527	Ethanolamine utilization protein, possible chaperonin [Amino acid transport and metabolism]; Region: EutJ; COG4820
696406008528	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
696406008529	nucleotide binding site [chemical binding]; other site
696406008530	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
696406008531	putative catalytic cysteine [active]
696406008532	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
696406008533	Hexamer/Pentamer interface [polypeptide binding]; other site
696406008534	central pore; other site
696406008535	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
696406008536	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
696406008537	Hexamer interface [polypeptide binding]; other site
696406008538	Putative hexagonal pore residue; other site
696406008539	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
696406008540	ethanolamine utilization cobalamin adenosyltransferase; Provisional; Region: PRK15020
696406008541	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
696406008542	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutQ; COG4766
696406008543	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
696406008544	G1 box; other site
696406008545	GTP/Mg2+ binding site [chemical binding]; other site
696406008546	G2 box; other site
696406008547	Switch I region; other site
696406008548	G3 box; other site
696406008549	Switch II region; other site
696406008550	G4 box; other site
696406008551	G5 box; other site
696406008552	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
696406008553	putative hexamer interface [polypeptide binding]; other site
696406008554	putative hexagonal pore; other site
696406008555	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
696406008556	Malic enzyme, N-terminal domain; Region: malic; pfam00390
696406008557	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
696406008558	putative NAD(P) binding site [chemical binding]; other site
696406008559	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
696406008560	transaldolase-like protein; Provisional; Region: PTZ00411
696406008561	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
696406008562	active site
696406008563	dimer interface [polypeptide binding]; other site
696406008564	catalytic residue [active]
696406008565	transketolase; Reviewed; Region: PRK12753
696406008566	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
696406008567	TPP-binding site [chemical binding]; other site
696406008568	dimer interface [polypeptide binding]; other site
696406008569	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
696406008570	PYR/PP interface [polypeptide binding]; other site
696406008571	dimer interface [polypeptide binding]; other site
696406008572	TPP binding site [chemical binding]; other site
696406008573	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
696406008574	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
696406008575	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
696406008576	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
696406008577	dimer interface [polypeptide binding]; other site
696406008578	ADP-ribose binding site [chemical binding]; other site
696406008579	active site
696406008580	nudix motif; other site
696406008581	metal binding site [ion binding]; metal-binding site
696406008582	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12769
696406008583	4Fe-4S binding domain; Region: Fer4; pfam00037
696406008584	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
696406008585	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
696406008586	nitrate/nitrite sensor protein NarQ; Provisional; Region: PRK10935
696406008587	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
696406008588	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
696406008589	dimerization interface [polypeptide binding]; other site
696406008590	Histidine kinase; Region: HisKA_3; pfam07730
696406008591	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406008592	ATP binding site [chemical binding]; other site
696406008593	Mg2+ binding site [ion binding]; other site
696406008594	G-X-G motif; other site
696406008595	aminoglycoside/multidrug efflux system; Provisional; Region: PRK10555
696406008596	Protein export membrane protein; Region: SecD_SecF; cl14618
696406008597	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
696406008598	ArsC family; Region: ArsC; pfam03960
696406008599	putative catalytic residues [active]
696406008600	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
696406008601	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
696406008602	metal binding site [ion binding]; metal-binding site
696406008603	dimer interface [polypeptide binding]; other site
696406008604	hypothetical protein; Provisional; Region: PRK13664
696406008605	putative hydrolase; Provisional; Region: PRK11460
696406008606	Phospholipase/Carboxylesterase; Region: Abhydrolase_2; pfam02230
696406008607	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
696406008608	Helicase; Region: Helicase_RecD; pfam05127
696406008609	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
696406008610	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
696406008611	Predicted metalloprotease [General function prediction only]; Region: COG2321
696406008612	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
696406008613	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
696406008614	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
696406008615	ATP binding site [chemical binding]; other site
696406008616	active site
696406008617	substrate binding site [chemical binding]; other site
696406008618	lipoprotein; Provisional; Region: PRK11679
696406008619	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
696406008620	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
696406008621	dihydrodipicolinate synthase; Region: dapA; TIGR00674
696406008622	dimer interface [polypeptide binding]; other site
696406008623	active site
696406008624	catalytic residue [active]
696406008625	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
696406008626	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
696406008627	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
696406008628	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
696406008629	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
696406008630	catalytic triad [active]
696406008631	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
696406008632	4Fe-4S binding domain; Region: Fer4; pfam00037
696406008633	hydrogenase 4 subunit B; Validated; Region: PRK06521
696406008634	hydrogenase 4 subunit B; Validated; Region: PRK06521
696406008635	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
696406008636	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
696406008637	NADH dehydrogenase; Region: NADHdh; cl00469
696406008638	hydrogenase 4 subunit D; Validated; Region: PRK06525
696406008639	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
696406008640	hydrogenase 4 membrane subunit; Provisional; Region: hyfE; PRK11492
696406008641	hydrogenase 4 subunit F; Validated; Region: PRK06458
696406008642	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
696406008643	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
696406008644	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
696406008645	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
696406008646	hydrogenase 4 subunit H; Validated; Region: PRK08222
696406008647	4Fe-4S binding domain; Region: Fer4; pfam00037
696406008648	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
696406008649	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
696406008650	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains [Transcription / Signal transduction mechanisms]; Region: FhlA; COG3604
696406008651	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
696406008652	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406008653	Walker A motif; other site
696406008654	ATP binding site [chemical binding]; other site
696406008655	Walker B motif; other site
696406008656	arginine finger; other site
696406008657	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
696406008658	putative formate transporter; Provisional; Region: focB; PRK09713
696406008659	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
696406008660	Domain of unknown function DUF20; Region: UPF0118; pfam01594
696406008661	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
696406008662	Peptidase family M48; Region: Peptidase_M48; cl12018
696406008663	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
696406008664	ArsC family; Region: ArsC; pfam03960
696406008665	catalytic residues [active]
696406008666	DNA replication initiation factor; Provisional; Region: PRK08084
696406008667	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
696406008668	uracil transporter; Provisional; Region: PRK10720
696406008669	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
696406008670	active site
696406008671	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
696406008672	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
696406008673	dimerization interface [polypeptide binding]; other site
696406008674	putative ATP binding site [chemical binding]; other site
696406008675	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
696406008676	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
696406008677	active site
696406008678	substrate binding site [chemical binding]; other site
696406008679	cosubstrate binding site; other site
696406008680	catalytic site [active]
696406008681	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
696406008682	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
696406008683	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
696406008684	Catalytic C-terminal domain, first repeat, of prokaryotic polyphosphate kinase 1 and similar proteins; Region: PLDc_PPK1_C1; cd09114
696406008685	domain interface [polypeptide binding]; other site
696406008686	active site
696406008687	catalytic site [active]
696406008688	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
696406008689	putative active site [active]
696406008690	catalytic site [active]
696406008691	exopolyphosphatase; Provisional; Region: PRK10854
696406008692	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
696406008693	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
696406008694	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
696406008695	MASE1; Region: MASE1; pfam05231
696406008696	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
696406008697	diguanylate cyclase; Region: GGDEF; smart00267
696406008698	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
696406008699	Protein of unknown function (DUF2633); Region: DUF2633; pfam11119
696406008700	Glycine zipper 2TM domain; Region: Rick_17kDa_Anti; cl10470
696406008701	Protein of unknown function (DUF2514); Region: DUF2514; pfam10721
696406008702	Predicted chitinase [General function prediction only]; Region: COG3179
696406008703	Protein of unknown function (DUF754); Region: DUF754; pfam05449
696406008704	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
696406008705	Prophage antirepressor [Transcription]; Region: COG3617
696406008706	BRO family, N-terminal domain; Region: Bro-N; smart01040
696406008707	cytochrome b; Validated; Region: CYTB; MTH00046
696406008708	structural protein; Region: PHA01972
696406008709	virion protein; Provisional; Region: V; PHA02564
696406008710	hypothetical protein; Region: PHA01733
696406008711	hypothetical protein; Region: PHA00661
696406008712	hypothetical protein; Region: PHA00662
696406008713	hypothetical protein; Region: PHA00669
696406008714	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
696406008715	hypothetical protein; Region: PHA00664
696406008716	major capsid protein; Region: PHA00665
696406008717	putative protease; Region: PHA00666
696406008718	hypothetical protein; Region: PHA00670
696406008719	Bacteriophage head to tail connecting protein; Region: Head-tail_con; pfam12236
696406008720	hypothetical protein; Region: PHA01971
696406008721	Terminase small subunit; Region: Terminase_2; pfam03592
696406008722	Protein of unknown function (DUF551); Region: DUF551; pfam04448
696406008723	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
696406008724	Protein of unknown function (DUF1064); Region: DUF1064; pfam06356
696406008725	Replication protein P; Region: Phage_lambda_P; pfam06992
696406008726	Pyocin large subunit [General function prediction only]; Region: COG5529
696406008727	Helix-turn-helix domain; Region: HTH_36; pfam13730
696406008728	primosomal protein DnaI; Provisional; Region: PRK02854
696406008729	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
696406008730	sequence-specific DNA binding site [nucleotide binding]; other site
696406008731	salt bridge; other site
696406008732	PDDEXK-like domain of unknown function (DUF3799); Region: DUF3799; pfam12684
696406008733	RecT family; Region: RecT; pfam03837
696406008734	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523
696406008735	MT-A70; Region: MT-A70; cl01947
696406008736	Protein of unknown function (DUF1382); Region: DUF1382; pfam07131
696406008737	integrase; Provisional; Region: PRK09692
696406008738	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
696406008739	active site
696406008740	Int/Topo IB signature motif; other site
696406008741	GMP synthase; Reviewed; Region: guaA; PRK00074
696406008742	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
696406008743	AMP/PPi binding site [chemical binding]; other site
696406008744	candidate oxyanion hole; other site
696406008745	catalytic triad [active]
696406008746	potential glutamine specificity residues [chemical binding]; other site
696406008747	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
696406008748	ATP Binding subdomain [chemical binding]; other site
696406008749	Ligand Binding sites [chemical binding]; other site
696406008750	Dimerization subdomain; other site
696406008751	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
696406008752	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
696406008753	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
696406008754	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
696406008755	active site
696406008756	exodeoxyribonuclease VII, large subunit; Region: xseA; TIGR00237
696406008757	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
696406008758	generic binding surface II; other site
696406008759	generic binding surface I; other site
696406008760	Protein of unknown function (DUF1407); Region: DUF1407; pfam07191
696406008761	GTP-binding protein Der; Reviewed; Region: PRK00093
696406008762	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
696406008763	G1 box; other site
696406008764	GTP/Mg2+ binding site [chemical binding]; other site
696406008765	Switch I region; other site
696406008766	G2 box; other site
696406008767	Switch II region; other site
696406008768	G3 box; other site
696406008769	G4 box; other site
696406008770	G5 box; other site
696406008771	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
696406008772	G1 box; other site
696406008773	GTP/Mg2+ binding site [chemical binding]; other site
696406008774	Switch I region; other site
696406008775	G2 box; other site
696406008776	G3 box; other site
696406008777	Switch II region; other site
696406008778	G4 box; other site
696406008779	G5 box; other site
696406008780	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
696406008781	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cd00216
696406008782	Trp docking motif [polypeptide binding]; other site
696406008783	active site
696406008784	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
696406008785	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
696406008786	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
696406008787	dimer interface [polypeptide binding]; other site
696406008788	motif 1; other site
696406008789	active site
696406008790	motif 2; other site
696406008791	motif 3; other site
696406008792	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
696406008793	anticodon binding site; other site
696406008794	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
696406008795	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
696406008796	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
696406008797	cytoskeletal protein RodZ; Provisional; Region: PRK10856
696406008798	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
696406008799	non-specific DNA binding site [nucleotide binding]; other site
696406008800	salt bridge; other site
696406008801	sequence-specific DNA binding site [nucleotide binding]; other site
696406008802	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
696406008803	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
696406008804	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
696406008805	FeS/SAM binding site; other site
696406008806	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
696406008807	active site
696406008808	multimer interface [polypeptide binding]; other site
696406008809	penicillin-binding protein 1C; Provisional; Region: PRK11240
696406008810	Transglycosylase; Region: Transgly; pfam00912
696406008811	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
696406008812	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
696406008813	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
696406008814	MG2 domain; Region: A2M_N; pfam01835
696406008815	Alpha-2-macroglobulin family; Region: A2M; pfam00207
696406008816	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
696406008817	surface patch; other site
696406008818	thioester region; other site
696406008819	specificity defining residues; other site
696406008820	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
696406008821	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
696406008822	active site residue [active]
696406008823	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
696406008824	active site residue [active]
696406008825	enhanced serine sensitivity protein SseB; Provisional; Region: PRK11611
696406008826	aminopeptidase B; Provisional; Region: PRK05015
696406008827	Peptidase; Region: DUF3663; pfam12404
696406008828	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
696406008829	interface (dimer of trimers) [polypeptide binding]; other site
696406008830	Substrate-binding/catalytic site; other site
696406008831	Zn-binding sites [ion binding]; other site
696406008832	hypothetical protein; Provisional; Region: PRK10721
696406008833	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
696406008834	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
696406008835	catalytic loop [active]
696406008836	iron binding site [ion binding]; other site
696406008837	chaperone protein HscA; Provisional; Region: hscA; PRK05183
696406008838	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
696406008839	nucleotide binding site [chemical binding]; other site
696406008840	putative NEF/HSP70 interaction site [polypeptide binding]; other site
696406008841	SBD interface [polypeptide binding]; other site
696406008842	co-chaperone HscB; Provisional; Region: hscB; PRK05014
696406008843	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
696406008844	HSP70 interaction site [polypeptide binding]; other site
696406008845	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
696406008846	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
696406008847	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
696406008848	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
696406008849	trimerization site [polypeptide binding]; other site
696406008850	active site
696406008851	cysteine desulfurase; Provisional; Region: PRK14012
696406008852	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
696406008853	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
696406008854	catalytic residue [active]
696406008855	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
696406008856	Rrf2 family protein; Region: rrf2_super; TIGR00738
696406008857	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
696406008858	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
696406008859	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
696406008860	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
696406008861	active site
696406008862	dimerization interface [polypeptide binding]; other site
696406008863	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
696406008864	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
696406008865	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
696406008866	PRD domain; Region: PRD; pfam00874
696406008867	PRD domain; Region: PRD; pfam00874
696406008868	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
696406008869	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406008870	putative substrate translocation pore; other site
696406008871	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
696406008872	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406008873	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
696406008874	dimerization interface [polypeptide binding]; other site
696406008875	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
696406008876	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
696406008877	iron-sulfur cluster [ion binding]; other site
696406008878	[2Fe-2S] cluster binding site [ion binding]; other site
696406008879	C-terminal catalytic domain of the oxygenase alpha subunit of naphthalene 1,2-dioxygenase (NDO) and related aromatic ring hydroxylating dioxygenases; Region: RHO_alpha_C_NDO-like; cd08881
696406008880	beta subunit interface [polypeptide binding]; other site
696406008881	alpha subunit interface [polypeptide binding]; other site
696406008882	active site
696406008883	substrate binding site [chemical binding]; other site
696406008884	Fe binding site [ion binding]; other site
696406008885	Ring hydroxylating dioxygenase beta subunit. This subunit has a similar structure to NTF-2, Ketosteroid isomerase and scytalone dehydratase.The degradation of aromatic compounds by aerobic bacteria frequently begins with the dihydroxylation of the...; Region: ring_hydroxylating_dioxygenases_beta; cd00667
696406008886	inter-subunit interface; other site
696406008887	Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO). The RO family comprise a...; Region: Rieske_RO_ferredoxin; cd03528
696406008888	[2Fe-2S] cluster binding site [ion binding]; other site
696406008889	2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase; Provisional; Region: PRK06200
696406008890	cis-biphenyl-2,3-dihydrodiol-2,3-dehydrogenase (BphB)-like, classical (c) SDRs; Region: BphB-like_SDR_c; cd05348
696406008891	NAD binding site [chemical binding]; other site
696406008892	active site
696406008893	phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional; Region: PRK09754
696406008894	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
696406008895	Predicted membrane protein [Function unknown]; Region: COG2259
696406008896	aldose 1-epimerase, similar to Escherichia coli YphB; Region: Aldose_epim_Ec_YphB; cd09021
696406008897	active site
696406008898	catalytic residues [active]
696406008899	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
696406008900	L-threonine dehydrogenase (TDH)-like; Region: THR_DH_like; cd08239
696406008901	putative NAD(P) binding site [chemical binding]; other site
696406008902	catalytic Zn binding site [ion binding]; other site
696406008903	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
696406008904	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
696406008905	TM-ABC transporter signature motif; other site
696406008906	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
696406008907	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
696406008908	Walker A/P-loop; other site
696406008909	ATP binding site [chemical binding]; other site
696406008910	Q-loop/lid; other site
696406008911	ABC transporter signature motif; other site
696406008912	Walker B; other site
696406008913	D-loop; other site
696406008914	H-loop/switch region; other site
696406008915	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
696406008916	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
696406008917	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
696406008918	ligand binding site [chemical binding]; other site
696406008919	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
696406008920	TPR motif; other site
696406008921	Tetratricopeptide repeat; Region: TPR_16; pfam13432
696406008922	binding surface
696406008923	TPR repeat; Region: TPR_11; pfam13414
696406008924	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
696406008925	TPR motif; other site
696406008926	binding surface
696406008927	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
696406008928	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
696406008929	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
696406008930	nucleotide binding site [chemical binding]; other site
696406008931	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
696406008932	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
696406008933	dimer interface [polypeptide binding]; other site
696406008934	active site
696406008935	glycine-pyridoxal phosphate binding site [chemical binding]; other site
696406008936	folate binding site [chemical binding]; other site
696406008937	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
696406008938	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
696406008939	heme-binding site [chemical binding]; other site
696406008940	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
696406008941	FAD binding pocket [chemical binding]; other site
696406008942	FAD binding motif [chemical binding]; other site
696406008943	phosphate binding motif [ion binding]; other site
696406008944	beta-alpha-beta structure motif; other site
696406008945	NAD binding pocket [chemical binding]; other site
696406008946	Heme binding  pocket [chemical binding]; other site
696406008947	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
696406008948	Nitrogen regulatory protein P-II; Region: P-II; smart00938
696406008949	response regulator GlrR; Provisional; Region: PRK15115
696406008950	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406008951	active site
696406008952	phosphorylation site [posttranslational modification]
696406008953	intermolecular recognition site; other site
696406008954	dimerization interface [polypeptide binding]; other site
696406008955	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406008956	Walker A motif; other site
696406008957	ATP binding site [chemical binding]; other site
696406008958	Walker B motif; other site
696406008959	arginine finger; other site
696406008960	hypothetical protein; Provisional; Region: PRK10722
696406008961	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
696406008962	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
696406008963	dimer interface [polypeptide binding]; other site
696406008964	phosphorylation site [posttranslational modification]
696406008965	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406008966	ATP binding site [chemical binding]; other site
696406008967	Mg2+ binding site [ion binding]; other site
696406008968	G-X-G motif; other site
696406008969	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
696406008970	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
696406008971	dimerization interface [polypeptide binding]; other site
696406008972	ATP binding site [chemical binding]; other site
696406008973	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
696406008974	dimerization interface [polypeptide binding]; other site
696406008975	ATP binding site [chemical binding]; other site
696406008976	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
696406008977	putative active site [active]
696406008978	catalytic triad [active]
696406008979	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
696406008980	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
696406008981	substrate binding pocket [chemical binding]; other site
696406008982	membrane-bound complex binding site; other site
696406008983	hinge residues; other site
696406008984	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
696406008985	N-acetyl-D-glucosamine binding site [chemical binding]; other site
696406008986	catalytic residue [active]
696406008987	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
696406008988	nucleoside/Zn binding site; other site
696406008989	dimer interface [polypeptide binding]; other site
696406008990	catalytic motif [active]
696406008991	hypothetical protein; Provisional; Region: PRK11590
696406008992	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
696406008993	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
696406008994	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
696406008995	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
696406008996	putative active site [active]
696406008997	holo-[acyl-carrier-protein] synthase; Region: acpS; TIGR00516
696406008998	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
696406008999	active site
696406009000	hydrophilic channel; other site
696406009001	dimerization interface [polypeptide binding]; other site
696406009002	catalytic residues [active]
696406009003	active site lid [active]
696406009004	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
696406009005	Recombination protein O N terminal; Region: RecO_N; pfam11967
696406009006	Recombination protein O C terminal; Region: RecO_C; pfam02565
696406009007	GTPase Era; Reviewed; Region: era; PRK00089
696406009008	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
696406009009	G1 box; other site
696406009010	GTP/Mg2+ binding site [chemical binding]; other site
696406009011	Switch I region; other site
696406009012	G2 box; other site
696406009013	Switch II region; other site
696406009014	G3 box; other site
696406009015	G4 box; other site
696406009016	G5 box; other site
696406009017	KH domain; Region: KH_2; pfam07650
696406009018	ribonuclease III; Reviewed; Region: rnc; PRK00102
696406009019	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
696406009020	dimerization interface [polypeptide binding]; other site
696406009021	active site
696406009022	metal binding site [ion binding]; metal-binding site
696406009023	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
696406009024	dsRNA binding site [nucleotide binding]; other site
696406009025	signal peptidase I; Provisional; Region: PRK10861
696406009026	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
696406009027	Catalytic site [active]
696406009028	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
696406009029	GTP-binding protein LepA; Provisional; Region: PRK05433
696406009030	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
696406009031	G1 box; other site
696406009032	putative GEF interaction site [polypeptide binding]; other site
696406009033	GTP/Mg2+ binding site [chemical binding]; other site
696406009034	Switch I region; other site
696406009035	G2 box; other site
696406009036	G3 box; other site
696406009037	Switch II region; other site
696406009038	G4 box; other site
696406009039	G5 box; other site
696406009040	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
696406009041	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
696406009042	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
696406009043	SoxR reducing system protein RseC; Provisional; Region: PRK10862
696406009044	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
696406009045	anti-sigma E factor; Provisional; Region: rseB; PRK09455
696406009046	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
696406009047	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
696406009048	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
696406009049	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
696406009050	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
696406009051	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
696406009052	DNA binding residues [nucleotide binding]
696406009053	L-aspartate oxidase; Provisional; Region: PRK09077
696406009054	L-aspartate oxidase; Provisional; Region: PRK06175
696406009055	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
696406009056	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
696406009057	Methyltransferase domain; Region: Methyltransf_26; pfam13659
696406009058	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
696406009059	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
696406009060	ATP binding site [chemical binding]; other site
696406009061	Mg++ binding site [ion binding]; other site
696406009062	motif III; other site
696406009063	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
696406009064	nucleotide binding region [chemical binding]; other site
696406009065	ATP-binding site [chemical binding]; other site
696406009066	Transcriptional regulator [Transcription]; Region: LysR; COG0583
696406009067	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406009068	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
696406009069	dimerization interface [polypeptide binding]; other site
696406009070	cysteine/O-acetylserine exporter; Provisional; Region: PRK10323
696406009071	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
696406009072	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
696406009073	ligand binding site [chemical binding]; other site
696406009074	active site
696406009075	UGI interface [polypeptide binding]; other site
696406009076	catalytic site [active]
696406009077	putative methyltransferase; Provisional; Region: PRK10864
696406009078	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
696406009079	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
696406009080	thioredoxin 2; Provisional; Region: PRK10996
696406009081	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
696406009082	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
696406009083	catalytic residues [active]
696406009084	Uncharacterized conserved protein [Function unknown]; Region: COG3148
696406009085	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
696406009086	CoA binding domain; Region: CoA_binding_2; pfam13380
696406009087	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
696406009088	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
696406009089	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
696406009090	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
696406009091	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
696406009092	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
696406009093	domain interface [polypeptide binding]; other site
696406009094	putative active site [active]
696406009095	catalytic site [active]
696406009096	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
696406009097	domain interface [polypeptide binding]; other site
696406009098	putative active site [active]
696406009099	catalytic site [active]
696406009100	lipoprotein; Provisional; Region: PRK10759
696406009101	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
696406009102	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406009103	putative substrate translocation pore; other site
696406009104	protein disaggregation chaperone; Provisional; Region: PRK10865
696406009105	Clp amino terminal domain; Region: Clp_N; pfam02861
696406009106	Clp amino terminal domain; Region: Clp_N; pfam02861
696406009107	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406009108	Walker A motif; other site
696406009109	ATP binding site [chemical binding]; other site
696406009110	Walker B motif; other site
696406009111	arginine finger; other site
696406009112	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406009113	Walker A motif; other site
696406009114	ATP binding site [chemical binding]; other site
696406009115	Walker B motif; other site
696406009116	arginine finger; other site
696406009117	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
696406009118	hypothetical protein; Provisional; Region: PRK10723
696406009119	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
696406009120	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
696406009121	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
696406009122	RNA binding surface [nucleotide binding]; other site
696406009123	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
696406009124	active site
696406009125	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
696406009126	Protein of unknown function (DUF3897); Region: DUF3897; cl17494
696406009127	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
696406009128	30S subunit binding site; other site
696406009129	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
696406009130	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
696406009131	Prephenate dehydratase; Region: PDT; pfam00800
696406009132	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
696406009133	putative L-Phe binding site [chemical binding]; other site
696406009134	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
696406009135	chorismate mutase domain of T-protein; Region: CM_T; TIGR01799
696406009136	prephenate dehydrogenase; Validated; Region: PRK08507
696406009137	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
696406009138	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
696406009139	lipoprotein; Provisional; Region: PRK11443
696406009140	Protein of unknown function (DUF2799); Region: DUF2799; pfam10973
696406009141	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
696406009142	putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966
696406009143	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
696406009144	metal binding site [ion binding]; metal-binding site
696406009145	active site
696406009146	I-site; other site
696406009147	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
696406009148	ligand binding site [chemical binding]; other site
696406009149	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
696406009150	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
696406009151	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
696406009152	RimM N-terminal domain; Region: RimM; pfam01782
696406009153	PRC-barrel domain; Region: PRC; pfam05239
696406009154	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
696406009155	signal recognition particle protein; Provisional; Region: PRK10867
696406009156	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
696406009157	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
696406009158	P loop; other site
696406009159	GTP binding site [chemical binding]; other site
696406009160	Signal peptide binding domain; Region: SRP_SPB; pfam02978
696406009161	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
696406009162	hypothetical protein; Provisional; Region: PRK11573
696406009163	Domain of unknown function DUF21; Region: DUF21; pfam01595
696406009164	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
696406009165	Transporter associated domain; Region: CorC_HlyC; smart01091
696406009166	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
696406009167	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
696406009168	dimer interface [polypeptide binding]; other site
696406009169	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
696406009170	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
696406009171	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
696406009172	recombination and repair protein; Provisional; Region: PRK10869
696406009173	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
696406009174	Walker A/P-loop; other site
696406009175	ATP binding site [chemical binding]; other site
696406009176	Q-loop/lid; other site
696406009177	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
696406009178	Q-loop/lid; other site
696406009179	ABC transporter signature motif; other site
696406009180	Walker B; other site
696406009181	D-loop; other site
696406009182	H-loop/switch region; other site
696406009183	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
696406009184	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
696406009185	hypothetical protein; Validated; Region: PRK01777
696406009186	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
696406009187	putative coenzyme Q binding site [chemical binding]; other site
696406009188	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
696406009189	SmpB-tmRNA interface; other site
696406009190	DinI-like family; Region: DinI; pfam06183
696406009191	Phage-related protein, tail component [Function unknown]; Region: COG4733
696406009192	Putative phage tail protein; Region: Phage-tail_3; pfam13550
696406009193	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
696406009194	Interdomain contacts; other site
696406009195	Cytokine receptor motif; other site
696406009196	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
696406009197	Phage-related protein, tail component [Function unknown]; Region: COG4723
696406009198	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
696406009199	MPN+ (JAMM) motif; other site
696406009200	Zinc-binding site [ion binding]; other site
696406009201	NlpC/P60 family; Region: NLPC_P60; pfam00877
696406009202	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
696406009203	Phage minor tail protein L; Region: Phage_tail_L; pfam05100
696406009204	Phage minor tail protein; Region: Phage_min_tail; pfam05939
696406009205	Phage-related minor tail protein [Function unknown]; Region: COG5281
696406009206	tape measure domain; Region: tape_meas_nterm; TIGR02675
696406009207	Tail length tape measure protein; Region: Phage_HK97_TLTM; pfam06120
696406009208	Protein of unknown function (DUF1635); Region: DUF1635; pfam07795
696406009209	phage tail tape measure protein, lambda family; Region: tape_meas_lam_C; TIGR01541
696406009210	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
696406009211	Protein of unknown function (DUF4035); Region: DUF4035; pfam13227
696406009212	Phage tail assembly chaperone; Region: Phage_TAC; pfam06222
696406009213	Protein of unknown function (DUF3168); Region: DUF3168; pfam11367
696406009214	phage protein, HK97 gp10 family; Region: phge_HK97_gp10; TIGR01725
696406009215	Bacteriophage head-tail adaptor [General function prediction only]; Region: COG5614
696406009216	Head-Tail Connector Proteins gp6 and gp15, and similar proteins; Region: gp6_gp15_like; cd08051
696406009217	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
696406009218	Phage capsid family; Region: Phage_capsid; pfam05065
696406009219	phage prohead protease, HK97 family; Region: proheadase_HK97; TIGR01543
696406009220	Phage-related protein [Function unknown]; Region: COG4695
696406009221	Phage portal protein; Region: Phage_portal; pfam04860
696406009222	Phage Terminase; Region: Terminase_1; pfam03354
696406009223	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
696406009224	active site
696406009225	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
696406009226	active site
696406009227	Predicted chitinase [General function prediction only]; Region: COG3179
696406009228	catalytic residue [active]
696406009229	Protein of unknown function (DUF754); Region: DUF754; pfam05449
696406009230	Protein of unknown function (DUF3927); Region: DUF3927; pfam13064
696406009231	tellurite resistance protein terB; Region: terB; cd07176
696406009232	putative metal binding site [ion binding]; other site
696406009233	Antitermination protein; Region: Antiterm; pfam03589
696406009234	Antitermination protein; Region: Antiterm; pfam03589
696406009235	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4643
696406009236	Zinc-binding domain of primase-helicase; Region: Prim_Zn_Ribbon; smart00778
696406009237	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
696406009238	active site
696406009239	metal binding site [ion binding]; metal-binding site
696406009240	interdomain interaction site; other site
696406009241	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
696406009242	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
696406009243	ATP binding site [chemical binding]; other site
696406009244	putative Mg++ binding site [ion binding]; other site
696406009245	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
696406009246	nucleotide binding region [chemical binding]; other site
696406009247	ATP-binding site [chemical binding]; other site
696406009248	Domain of unknown function (DUF3596); Region: DUF3596; pfam12167
696406009249	Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N2; pfam13495
696406009250	phiCTX phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various phage and bacterial integrases, including those similar to phage integrases: Bordetella and...; Region: INT_phiCTX_C; cd01191
696406009251	Int/Topo IB signature motif; other site
696406009252	Autotransporter beta-domain; Region: Autotransporter; cl17461
696406009253	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
696406009254	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
696406009255	active site
696406009256	catalytic site [active]
696406009257	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cd00250
696406009258	substrate binding pocket [chemical binding]; other site
696406009259	active site
696406009260	iron coordination sites [ion binding]; other site
696406009261	Predicted dehydrogenase [General function prediction only]; Region: COG0579
696406009262	hydroxyglutarate oxidase; Provisional; Region: PRK11728
696406009263	succinate-semialdehyde dehydrogenase I; Provisional; Region: gabD; PRK11241
696406009264	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
696406009265	tetramerization interface [polypeptide binding]; other site
696406009266	NAD(P) binding site [chemical binding]; other site
696406009267	catalytic residues [active]
696406009268	4-aminobutyrate aminotransferase; Validated; Region: PRK08088
696406009269	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
696406009270	inhibitor-cofactor binding pocket; inhibition site
696406009271	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406009272	catalytic residue [active]
696406009273	gamma-aminobutyrate transporter; Provisional; Region: PRK10197
696406009274	DNA-binding transcriptional regulator CsiR; Provisional; Region: PRK11534
696406009275	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
696406009276	DNA-binding site [nucleotide binding]; DNA binding site
696406009277	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
696406009278	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
696406009279	bacterial OsmY and nodulation domain; Region: BON; smart00749
696406009280	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
696406009281	Uncharacterized homolog of Blt101 [Function unknown]; Region: COG0401
696406009282	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
696406009283	dimerization interface [polypeptide binding]; other site
696406009284	putative DNA binding site [nucleotide binding]; other site
696406009285	Transcriptional regulators [Transcription]; Region: MarR; COG1846
696406009286	putative Zn2+ binding site [ion binding]; other site
696406009287	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YgaP, and similar uncharacterized putative rhodanese-related sulfurtransferases; Region: RHOD_YgaP; cd01527
696406009288	active site residue [active]
696406009289	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
696406009290	DNA binding protein, nucleoid-associated; Provisional; Region: PRK10328
696406009291	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
696406009292	Protein of unknown function (DUF1144); Region: DUF1144; pfam06610
696406009293	hypothetical protein; Provisional; Region: PRK10556
696406009294	hypothetical protein; Provisional; Region: PRK10132
696406009295	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
696406009296	catalytic residues [active]
696406009297	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
696406009298	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
696406009299	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
696406009300	Class I ribonucleotide reductase; Region: RNR_I; cd01679
696406009301	active site
696406009302	dimer interface [polypeptide binding]; other site
696406009303	catalytic residues [active]
696406009304	effector binding site; other site
696406009305	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
696406009306	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
696406009307	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
696406009308	dimer interface [polypeptide binding]; other site
696406009309	putative radical transfer pathway; other site
696406009310	diiron center [ion binding]; other site
696406009311	tyrosyl radical; other site
696406009312	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
696406009313	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
696406009314	Walker A/P-loop; other site
696406009315	ATP binding site [chemical binding]; other site
696406009316	Q-loop/lid; other site
696406009317	ABC transporter signature motif; other site
696406009318	Walker B; other site
696406009319	D-loop; other site
696406009320	H-loop/switch region; other site
696406009321	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
696406009322	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
696406009323	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406009324	dimer interface [polypeptide binding]; other site
696406009325	conserved gate region; other site
696406009326	putative PBP binding loops; other site
696406009327	ABC-ATPase subunit interface; other site
696406009328	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
696406009329	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
696406009330	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
696406009331	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406009332	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
696406009333	putative L-valine exporter; Provisional; Region: PRK10408
696406009334	transcriptional repressor MprA; Provisional; Region: PRK10870
696406009335	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
696406009336	HlyD family secretion protein; Region: HlyD; pfam00529
696406009337	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
696406009338	HlyD family secretion protein; Region: HlyD_3; pfam13437
696406009339	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
696406009340	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406009341	putative substrate translocation pore; other site
696406009342	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406009343	S-ribosylhomocysteinase; Provisional; Region: PRK02260
696406009344	glutamate--cysteine ligase; Provisional; Region: PRK02107
696406009345	Predicted membrane protein [Function unknown]; Region: COG1238
696406009346	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
696406009347	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696406009348	motif II; other site
696406009349	carbon storage regulator; Provisional; Region: PRK01712
696406009350	tRNA synthetases class II (A); Region: tRNA-synt_2c; pfam01411
696406009351	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
696406009352	active site
696406009353	motif 3; other site
696406009354	alanine-tRNA ligase; Region: PLN02961
696406009355	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
696406009356	DHHA1 domain; Region: DHHA1; pfam02272
696406009357	recombination regulator RecX; Reviewed; Region: recX; PRK00117
696406009358	recombinase A; Provisional; Region: recA; PRK09354
696406009359	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
696406009360	hexamer interface [polypeptide binding]; other site
696406009361	Walker A motif; other site
696406009362	ATP binding site [chemical binding]; other site
696406009363	Walker B motif; other site
696406009364	hypothetical protein; Validated; Region: PRK03661
696406009365	Transglycosylase SLT domain; Region: SLT_2; pfam13406
696406009366	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
696406009367	N-acetyl-D-glucosamine binding site [chemical binding]; other site
696406009368	PTS system, glucitol/sorbitol-specific, IIC component; Region: EII-GUT; TIGR00821
696406009369	PTS system, glucitol/sorbitol-specific, IIBC component; Region: EIIBC-GUT; TIGR00825
696406009370	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
696406009371	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
696406009372	PTS system glucitol/sorbitol-specific transporter subunit IIA; Provisional; Region: PRK10377
696406009373	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
696406009374	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
696406009375	putative NAD(P) binding site [chemical binding]; other site
696406009376	active site
696406009377	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
696406009378	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
696406009379	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
696406009380	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
696406009381	D-arabinose 5-phosphate isomerase; Provisional; Region: gutQ; PRK11543
696406009382	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
696406009383	putative active site [active]
696406009384	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
696406009385	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
696406009386	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
696406009387	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406009388	Walker A motif; other site
696406009389	ATP binding site [chemical binding]; other site
696406009390	Walker B motif; other site
696406009391	arginine finger; other site
696406009392	anaerobic nitric oxide reductase flavorubredoxin; Provisional; Region: PRK05452
696406009393	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
696406009394	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
696406009395	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
696406009396	iron binding site [ion binding]; other site
696406009397	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
696406009398	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
696406009399	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
696406009400	Acylphosphatase; Region: Acylphosphatase; pfam00708
696406009401	HypF finger; Region: zf-HYPF; pfam07503
696406009402	HypF finger; Region: zf-HYPF; pfam07503
696406009403	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
696406009404	formate dehydrogenase-H ferredoxin subunit; Provisional; Region: PRK10330
696406009405	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
696406009406	Transcriptional regulators [Transcription]; Region: PurR; COG1609
696406009407	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
696406009408	DNA binding site [nucleotide binding]
696406009409	domain linker motif; other site
696406009410	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
696406009411	dimerization interface (closed form) [polypeptide binding]; other site
696406009412	ligand binding site [chemical binding]; other site
696406009413	PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC; Provisional; Region: PRK09796
696406009414	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
696406009415	active site turn [active]
696406009416	phosphorylation site [posttranslational modification]
696406009417	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
696406009418	cryptic 6-phospho-beta-glucosidase; Provisional; Region: PRK09852
696406009419	beta-galactosidase; Region: BGL; TIGR03356
696406009420	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
696406009421	nickel binding site [ion binding]; other site
696406009422	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
696406009423	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
696406009424	formate hydrogenlyase complex iron-sulfur subunit; Provisional; Region: PRK12387
696406009425	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
696406009426	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
696406009427	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
696406009428	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
696406009429	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
696406009430	NADH dehydrogenase; Region: NADHdh; cl00469
696406009431	formate hydrogenlyase subunit 3; Reviewed; Region: PRK08042
696406009432	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
696406009433	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
696406009434	formate hydrogenlyase regulatory protein HycA; Provisional; Region: PRK10198
696406009435	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
696406009436	hydrogenase nickel incorporation protein; Validated; Region: hypA; PRK03681
696406009437	hydrogenase nickel incorporation protein HypB; Provisional; Region: PRK10463
696406009438	hydrogenase assembly chaperone; Provisional; Region: PRK10409
696406009439	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
696406009440	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
696406009441	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
696406009442	dimerization interface [polypeptide binding]; other site
696406009443	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
696406009444	ATP binding site [chemical binding]; other site
696406009445	formate hydrogenlyase transcriptional activator FhlA; Provisional; Region: PRK15429
696406009446	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
696406009447	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
696406009448	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406009449	Walker A motif; other site
696406009450	ATP binding site [chemical binding]; other site
696406009451	Walker B motif; other site
696406009452	arginine finger; other site
696406009453	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
696406009454	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
696406009455	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
696406009456	MutS domain I; Region: MutS_I; pfam01624
696406009457	MutS domain II; Region: MutS_II; pfam05188
696406009458	MutS domain III; Region: MutS_III; pfam05192
696406009459	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
696406009460	Walker A/P-loop; other site
696406009461	ATP binding site [chemical binding]; other site
696406009462	Q-loop/lid; other site
696406009463	ABC transporter signature motif; other site
696406009464	Walker B; other site
696406009465	D-loop; other site
696406009466	H-loop/switch region; other site
696406009467	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
696406009468	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
696406009469	active site
696406009470	metal binding site [ion binding]; metal-binding site
696406009471	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
696406009472	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
696406009473	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
696406009474	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
696406009475	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
696406009476	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
696406009477	putative aldolase; Validated; Region: PRK08130
696406009478	active site
696406009479	intersubunit interface [polypeptide binding]; other site
696406009480	Zn2+ binding site [ion binding]; other site
696406009481	hypothetical protein; Provisional; Region: PRK09989
696406009482	putative transporter; Provisional; Region: PRK09821
696406009483	GntP family permease; Region: GntP_permease; pfam02447
696406009484	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
696406009485	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
696406009486	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
696406009487	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
696406009488	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
696406009489	DNA binding residues [nucleotide binding]
696406009490	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
696406009491	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
696406009492	Peptidase family M23; Region: Peptidase_M23; pfam01551
696406009493	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
696406009494	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406009495	S-adenosylmethionine binding site [chemical binding]; other site
696406009496	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
696406009497	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
696406009498	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
696406009499	Permutation of conserved domain; other site
696406009500	active site
696406009501	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
696406009502	homotrimer interaction site [polypeptide binding]; other site
696406009503	zinc binding site [ion binding]; other site
696406009504	CDP-binding sites; other site
696406009505	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
696406009506	substrate binding site; other site
696406009507	dimer interface; other site
696406009508	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
696406009509	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
696406009510	Protein of unknown function (DUF3561); Region: DUF3561; pfam12084
696406009511	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
696406009512	ligand-binding site [chemical binding]; other site
696406009513	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
696406009514	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
696406009515	CysD dimerization site [polypeptide binding]; other site
696406009516	G1 box; other site
696406009517	putative GEF interaction site [polypeptide binding]; other site
696406009518	GTP/Mg2+ binding site [chemical binding]; other site
696406009519	Switch I region; other site
696406009520	G2 box; other site
696406009521	G3 box; other site
696406009522	Switch II region; other site
696406009523	G4 box; other site
696406009524	G5 box; other site
696406009525	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
696406009526	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
696406009527	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
696406009528	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
696406009529	Active Sites [active]
696406009530	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
696406009531	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
696406009532	metal binding site [ion binding]; metal-binding site
696406009533	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I-E; cd09755
696406009534	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-E; cd09719
696406009535	CRISPR/Cas system-associated RAMP superfamily protein Cas6e; Region: Cas6_I-E; cd09664
696406009536	CRISPR-associated protein (Cas_Cas5); Region: Cas_Cas5d; pfam09704
696406009537	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-E; cd09645
696406009538	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I-E; cd09646
696406009539	CRISPR/Cas system-associated protein Cse2; Region: Cse2_I-E; cd09670
696406009540	CRISPR/Cas system-associated protein Cse1; Region: Cse1_I-E; cd09669
696406009541	helicase Cas3; Provisional; Region: PRK09694
696406009542	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
696406009543	CRISPR/Cas system-associated protein Cas3; Region: Cas3_I; cd09639
696406009544	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
696406009545	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
696406009546	Active Sites [active]
696406009547	sulfite reductase subunit beta; Provisional; Region: PRK13504
696406009548	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
696406009549	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
696406009550	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
696406009551	Flavodoxin; Region: Flavodoxin_1; pfam00258
696406009552	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
696406009553	FAD binding pocket [chemical binding]; other site
696406009554	FAD binding motif [chemical binding]; other site
696406009555	catalytic residues [active]
696406009556	NAD binding pocket [chemical binding]; other site
696406009557	phosphate binding motif [ion binding]; other site
696406009558	beta-alpha-beta structure motif; other site
696406009559	6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a...; Region: PTPS; cd00470
696406009560	homohexamer interface [polypeptide binding]; other site
696406009561	putative substrate stabilizing pore; other site
696406009562	pterin binding site; other site
696406009563	oxidoreductase; Provisional; Region: PRK10015
696406009564	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
696406009565	Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription]; Region: GlpP; COG1954
696406009566	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
696406009567	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
696406009568	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
696406009569	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
696406009570	Ligand binding site [chemical binding]; other site
696406009571	Electron transfer flavoprotein domain; Region: ETF; pfam01012
696406009572	Protein of unknown function (DUF2950); Region: DUF2950; pfam11453
696406009573	benzoate transport; Region: 2A0115; TIGR00895
696406009574	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406009575	putative substrate translocation pore; other site
696406009576	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
696406009577	FAD binding domain; Region: FAD_binding_4; pfam01565
696406009578	2-deoxy-D-gluconate 3-dehydrogenase; Provisional; Region: PRK06935
696406009579	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
696406009580	NADP binding site [chemical binding]; other site
696406009581	homodimer interface [polypeptide binding]; other site
696406009582	active site
696406009583	Major Facilitator Superfamily; Region: MFS_1; pfam07690
696406009584	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406009585	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
696406009586	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
696406009587	nucleotide binding site [chemical binding]; other site
696406009588	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
696406009589	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
696406009590	Beta-propeller domains of methanol dehydrogenase type [General function prediction only]; Region: COG1512
696406009591	Repair protein; Region: Repair_PSII; pfam04536
696406009592	enolase; Provisional; Region: eno; PRK00077
696406009593	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
696406009594	dimer interface [polypeptide binding]; other site
696406009595	metal binding site [ion binding]; metal-binding site
696406009596	substrate binding pocket [chemical binding]; other site
696406009597	CTP synthetase; Validated; Region: pyrG; PRK05380
696406009598	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
696406009599	Catalytic site [active]
696406009600	active site
696406009601	UTP binding site [chemical binding]; other site
696406009602	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
696406009603	active site
696406009604	putative oxyanion hole; other site
696406009605	catalytic triad [active]
696406009606	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
696406009607	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
696406009608	homodimer interface [polypeptide binding]; other site
696406009609	metal binding site [ion binding]; metal-binding site
696406009610	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
696406009611	homodimer interface [polypeptide binding]; other site
696406009612	active site
696406009613	putative chemical substrate binding site [chemical binding]; other site
696406009614	metal binding site [ion binding]; metal-binding site
696406009615	toxin MazF; Provisional; Region: PRK09907
696406009616	antitoxin MazE; Provisional; Region: PRK09798
696406009617	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
696406009618	HD domain; Region: HD_4; pfam13328
696406009619	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
696406009620	synthetase active site [active]
696406009621	NTP binding site [chemical binding]; other site
696406009622	metal binding site [ion binding]; metal-binding site
696406009623	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
696406009624	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
696406009625	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
696406009626	TRAM domain; Region: TRAM; pfam01938
696406009627	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406009628	S-adenosylmethionine binding site [chemical binding]; other site
696406009629	hybrid sensory histidine kinase BarA; Provisional; Region: PRK11107
696406009630	Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984
696406009631	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
696406009632	dimerization interface [polypeptide binding]; other site
696406009633	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
696406009634	dimer interface [polypeptide binding]; other site
696406009635	phosphorylation site [posttranslational modification]
696406009636	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406009637	ATP binding site [chemical binding]; other site
696406009638	Mg2+ binding site [ion binding]; other site
696406009639	G-X-G motif; other site
696406009640	Uncharacterized domain of BarA-like signal transduction histidine kinases [Signal transduction mechanisms]; Region: COG4999
696406009641	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406009642	active site
696406009643	phosphorylation site [posttranslational modification]
696406009644	intermolecular recognition site; other site
696406009645	dimerization interface [polypeptide binding]; other site
696406009646	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
696406009647	putative binding surface; other site
696406009648	active site
696406009649	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
696406009650	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
696406009651	active site
696406009652	tetramer interface [polypeptide binding]; other site
696406009653	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
696406009654	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
696406009655	active site
696406009656	tetramer interface [polypeptide binding]; other site
696406009657	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406009658	D-galactonate transporter; Region: 2A0114; TIGR00893
696406009659	putative substrate translocation pore; other site
696406009660	flavodoxin; Provisional; Region: PRK08105
696406009661	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
696406009662	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
696406009663	probable active site [active]
696406009664	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3098
696406009665	SecY interacting protein Syd; Provisional; Region: PRK04968
696406009666	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
696406009667	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
696406009668	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
696406009669	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
696406009670	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
696406009671	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
696406009672	serine transporter; Region: stp; TIGR00814
696406009673	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
696406009674	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
696406009675	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
696406009676	flap endonuclease-like protein; Provisional; Region: PRK09482
696406009677	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
696406009678	active site
696406009679	metal binding site 1 [ion binding]; metal-binding site
696406009680	putative 5' ssDNA interaction site; other site
696406009681	metal binding site 3; metal-binding site
696406009682	metal binding site 2 [ion binding]; metal-binding site
696406009683	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
696406009684	putative DNA binding site [nucleotide binding]; other site
696406009685	putative metal binding site [ion binding]; other site
696406009686	L-1,2-propanediol oxidoreductase; Provisional; Region: PRK10624
696406009687	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
696406009688	dimer interface [polypeptide binding]; other site
696406009689	active site
696406009690	metal binding site [ion binding]; metal-binding site
696406009691	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
696406009692	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
696406009693	intersubunit interface [polypeptide binding]; other site
696406009694	active site
696406009695	Zn2+ binding site [ion binding]; other site
696406009696	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
696406009697	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406009698	putative substrate translocation pore; other site
696406009699	L-fucose isomerase; Provisional; Region: fucI; PRK10991
696406009700	L-fucose isomerase (FucIase); FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose during glycolysis). L-fucose (or 6-deoxy-L-galactose) is found in blood group...; Region: L-fucose_isomerase; cd03556
696406009701	hexamer (dimer of trimers) interface [polypeptide binding]; other site
696406009702	trimer interface [polypeptide binding]; other site
696406009703	substrate binding site [chemical binding]; other site
696406009704	Mn binding site [ion binding]; other site
696406009705	L-fuculokinase; Provisional; Region: PRK10331
696406009706	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
696406009707	nucleotide binding site [chemical binding]; other site
696406009708	L-fucose mutarotase; Provisional; Region: fucU; PRK15420
696406009709	DNA-binding transcriptional activator FucR; Provisional; Region: PRK10411
696406009710	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
696406009711	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
696406009712	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
696406009713	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
696406009714	hypothetical protein; Provisional; Region: PRK10873
696406009715	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
696406009716	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406009717	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
696406009718	dimerization interface [polypeptide binding]; other site
696406009719	substrate binding pocket [chemical binding]; other site
696406009720	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
696406009721	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
696406009722	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
696406009723	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
696406009724	catalytic residue [active]
696406009725	CsdA-binding activator; Provisional; Region: PRK15019
696406009726	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
696406009727	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
696406009728	putative ATP binding site [chemical binding]; other site
696406009729	putative substrate interface [chemical binding]; other site
696406009730	murein transglycosylase A; Provisional; Region: mltA; PRK11162
696406009731	MltA specific insert domain; Region: MltA; pfam03562
696406009732	3D domain; Region: 3D; pfam06725
696406009733	AMIN domain; Region: AMIN; pfam11741
696406009734	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
696406009735	active site
696406009736	metal binding site [ion binding]; metal-binding site
696406009737	N-acetylglutamate synthase; Validated; Region: PRK05279
696406009738	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
696406009739	putative feedback inhibition sensing region; other site
696406009740	putative nucleotide binding site [chemical binding]; other site
696406009741	putative substrate binding site [chemical binding]; other site
696406009742	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
696406009743	Coenzyme A binding pocket [chemical binding]; other site
696406009744	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
696406009745	AAA domain; Region: AAA_30; pfam13604
696406009746	Family description; Region: UvrD_C_2; pfam13538
696406009747	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
696406009748	protease3; Provisional; Region: PRK15101
696406009749	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
696406009750	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
696406009751	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
696406009752	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
696406009753	exodeoxyribonuclease V, gamma subunit; Region: recC; TIGR01450
696406009754	hypothetical protein; Provisional; Region: PRK10332
696406009755	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
696406009756	hypothetical protein; Provisional; Region: PRK11521
696406009757	hypothetical protein; Provisional; Region: PRK10557
696406009758	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
696406009759	hypothetical protein; Provisional; Region: PRK10506
696406009760	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
696406009761	thymidylate synthase; Reviewed; Region: thyA; PRK01827
696406009762	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
696406009763	dimerization interface [polypeptide binding]; other site
696406009764	active site
696406009765	prolipoprotein diacylglyceryl transferase; Region: lgt; TIGR00544
696406009766	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
696406009767	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
696406009768	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
696406009769	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
696406009770	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
696406009771	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
696406009772	putative active site [active]
696406009773	Ap4A binding site [chemical binding]; other site
696406009774	nudix motif; other site
696406009775	putative metal binding site [ion binding]; other site
696406009776	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
696406009777	putative DNA-binding cleft [nucleotide binding]; other site
696406009778	putative DNA clevage site; other site
696406009779	molecular lever; other site
696406009780	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
696406009781	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
696406009782	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
696406009783	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
696406009784	active site
696406009785	catalytic tetrad [active]
696406009786	lysophospholipid transporter LplT; Provisional; Region: PRK11195
696406009787	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406009788	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
696406009789	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
696406009790	putative acyl-acceptor binding pocket; other site
696406009791	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
696406009792	acyl-activating enzyme (AAE) consensus motif; other site
696406009793	putative AMP binding site [chemical binding]; other site
696406009794	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
696406009795	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
696406009796	DNA binding site [nucleotide binding]
696406009797	domain linker motif; other site
696406009798	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
696406009799	dimerization interface (closed form) [polypeptide binding]; other site
696406009800	ligand binding site [chemical binding]; other site
696406009801	diaminopimelate decarboxylase; Provisional; Region: PRK11165
696406009802	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
696406009803	active site
696406009804	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
696406009805	substrate binding site [chemical binding]; other site
696406009806	catalytic residues [active]
696406009807	dimer interface [polypeptide binding]; other site
696406009808	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
696406009809	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406009810	The C-terminal substrate binding domain of LysR, transcriptional regulator for lysine biosynthesis, contains the type 2 periplasmic binding fold; Region: PBP2_LysR; cd08456
696406009811	putative dimerization interface [polypeptide binding]; other site
696406009812	putative racemase; Provisional; Region: PRK10200
696406009813	aspartate racemase; Region: asp_race; TIGR00035
696406009814	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
696406009815	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406009816	putative substrate translocation pore; other site
696406009817	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406009818	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
696406009819	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
696406009820	NADP binding site [chemical binding]; other site
696406009821	homodimer interface [polypeptide binding]; other site
696406009822	active site
696406009823	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
696406009824	putative acyltransferase; Provisional; Region: PRK05790
696406009825	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
696406009826	dimer interface [polypeptide binding]; other site
696406009827	active site
696406009828	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
696406009829	serine transporter; Region: stp; TIGR00814
696406009830	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315
696406009831	DNA binding residues [nucleotide binding]
696406009832	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
696406009833	type III secretion low calcium response chaperone LcrH/SycD; Region: LcrH_SycD; TIGR02552
696406009834	Tetratricopeptide repeat; Region: TPR_3; pfam07720
696406009835	Tetratricopeptide repeat; Region: TPR_3; pfam07720
696406009836	transcriptional regulator; Provisional; Region: PRK11906
696406009837	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
696406009838	DNA binding site [nucleotide binding]
696406009839	Tetratricopeptide repeat; Region: TPR_2; pfam07719
696406009840	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
696406009841	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
696406009842	DNA binding residues [nucleotide binding]
696406009843	dimerization interface [polypeptide binding]; other site
696406009844	invasion protein OrgB; Provisional; Region: PRK15322
696406009845	Bacterial type III secretion apparatus protein (OrgA_MxiK); Region: OrgA_MxiK; cl09716
696406009846	Bacterial type III secretion apparatus protein (OrgA_MxiK); Region: OrgA_MxiK; cl09716
696406009847	Type III secretory pathway, lipoprotein EscJ [Intracellular trafficking and secretion]; Region: EscJ; COG4669
696406009848	type III secretion system needle complex protein PrgJ; Provisional; Region: PRK15325
696406009849	Type III secretion needle MxiH like; Region: MxiH; cl09641
696406009850	type III secretion system needle complex protein PrgH; Provisional; Region: PRK15327; cl12363
696406009851	type III secretion protein SpaR/YscT/HrcT; Region: fliR_like_III; TIGR01401
696406009852	type III secretion system protein SpaQ; Provisional; Region: PRK15333
696406009853	FliP family; Region: FliP; cl00593
696406009854	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
696406009855	Glycosyl hydrolases family 15; Region: Glyco_hydro_15; pfam00723
696406009856	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
696406009857	Peptidase family M23; Region: Peptidase_M23; pfam01551
696406009858	xanthine dehydrogenase subunit XdhA; Provisional; Region: PRK09970
696406009859	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
696406009860	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
696406009861	xanthine dehydrogenase subunit XdhB; Provisional; Region: PRK09971
696406009862	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
696406009863	xanthine dehydrogenase subunit XdhC; Provisional; Region: PRK09908
696406009864	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
696406009865	catalytic loop [active]
696406009866	iron binding site [ion binding]; other site
696406009867	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
696406009868	GAF domain; Region: GAF; cl17456
696406009869	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
696406009870	PAS domain; Region: PAS; smart00091
696406009871	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406009872	Walker A motif; other site
696406009873	ATP binding site [chemical binding]; other site
696406009874	Walker B motif; other site
696406009875	arginine finger; other site
696406009876	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
696406009877	aspartate/ornithine carbamoyltransferase family protein; Validated; Region: PRK07200
696406009878	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
696406009879	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
696406009880	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
696406009881	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cd00640
696406009882	catalytic residue [active]
696406009883	peptidase; Reviewed; Region: PRK13004
696406009884	M20 Peptidases with similarity to acetylornithine deacetylases and succinyl-diaminopimelate desuccinylases; Region: M20_ArgE_DapE_like4; cd05649
696406009885	putative metal binding site [ion binding]; other site
696406009886	putative dimer interface [polypeptide binding]; other site
696406009887	D-hydantoinase; Region: D-hydantoinase; TIGR02033
696406009888	D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine...; Region: D-HYD; cd01314
696406009889	tetramer interface [polypeptide binding]; other site
696406009890	active site
696406009891	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
696406009892	carbamate kinase; Reviewed; Region: PRK12686
696406009893	putative substrate binding site [chemical binding]; other site
696406009894	homodimer interface [polypeptide binding]; other site
696406009895	nucleotide binding site [chemical binding]; other site
696406009896	nucleotide binding site [chemical binding]; other site
696406009897	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
696406009898	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
696406009899	XdhC Rossmann domain; Region: XdhC_C; pfam13478
696406009900	selenium-dependent molybdenum hydroxylase system protein, YqeB family; Region: matur_yqeB; TIGR03309
696406009901	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
696406009902	probable selenium-dependent hydroxylase accessory protein YqeC; Region: TIGR03172
696406009903	GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function; Region: GT_2_like_f; cd04182
696406009904	Ligand binding site; other site
696406009905	metal-binding site
696406009906	putative selenate reductase subunit YgfK; Provisional; Region: PRK09853
696406009907	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
696406009908	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
696406009909	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
696406009910	putative selenium metabolism protein SsnA; Region: Se_ssnA; TIGR03314
696406009911	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
696406009912	active site
696406009913	putative substrate binding pocket [chemical binding]; other site
696406009914	probable selenate reductase, FAD-binding subunit; Region: Se_sel_red_FAD; TIGR03312
696406009915	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
696406009916	putative hypoxanthine oxidase; Provisional; Region: PRK09800
696406009917	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
696406009918	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
696406009919	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
696406009920	uracil-xanthine permease; Region: ncs2; TIGR00801
696406009921	guanine deaminase; Provisional; Region: PRK09228
696406009922	Guanine deaminase (GDEase). Guanine deaminase is an aminohydrolase responsible for the conversion of guanine to xanthine and ammonia, the first step to utilize guanine as a nitrogen source. This reaction also removes the guanine base from the pool and...; Region: GDEase; cd01303
696406009923	active site
696406009924	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
696406009925	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
696406009926	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12809
696406009927	4Fe-4S binding domain; Region: Fer4; pfam00037
696406009928	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
696406009929	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
696406009930	xanthine permease; Region: pbuX; TIGR03173
696406009931	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
696406009932	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
696406009933	active site
696406009934	metal binding site [ion binding]; metal-binding site
696406009935	nudix motif; other site
696406009936	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
696406009937	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
696406009938	dimer interface [polypeptide binding]; other site
696406009939	putative anticodon binding site; other site
696406009940	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
696406009941	motif 1; other site
696406009942	active site
696406009943	motif 2; other site
696406009944	motif 3; other site
696406009945	peptide chain release factor 2; Provisional; Region: PRK08787
696406009946	This domain is found in peptide chain release factors; Region: PCRF; smart00937
696406009947	RF-1 domain; Region: RF-1; pfam00472
696406009948	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
696406009949	DHH family; Region: DHH; pfam01368
696406009950	DHHA1 domain; Region: DHHA1; pfam02272
696406009951	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
696406009952	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
696406009953	dimerization domain [polypeptide binding]; other site
696406009954	dimer interface [polypeptide binding]; other site
696406009955	catalytic residues [active]
696406009956	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
696406009957	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
696406009958	active site
696406009959	Int/Topo IB signature motif; other site
696406009960	flavodoxin FldB; Provisional; Region: PRK12359
696406009961	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
696406009962	hypothetical protein; Provisional; Region: PRK10878
696406009963	putative global regulator; Reviewed; Region: PRK09559
696406009964	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
696406009965	hemolysin; Provisional; Region: PRK15087
696406009966	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
696406009967	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
696406009968	6-phospho-beta-glucosidase BglA; Provisional; Region: PRK15014
696406009969	beta-galactosidase; Region: BGL; TIGR03356
696406009970	putative NAD(P)-binding oxidoreductase; Provisional; Region: PRK09730
696406009971	classical (c) SDRs; Region: SDR_c; cd05233
696406009972	NAD(P) binding site [chemical binding]; other site
696406009973	active site
696406009974	glycine dehydrogenase; Provisional; Region: PRK05367
696406009975	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
696406009976	tetramer interface [polypeptide binding]; other site
696406009977	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406009978	catalytic residue [active]
696406009979	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
696406009980	tetramer interface [polypeptide binding]; other site
696406009981	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406009982	catalytic residue [active]
696406009983	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
696406009984	lipoyl attachment site [posttranslational modification]; other site
696406009985	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
696406009986	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
696406009987	oxidoreductase; Provisional; Region: PRK08013
696406009988	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
696406009989	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
696406009990	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
696406009991	proline aminopeptidase P II; Provisional; Region: PRK10879
696406009992	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
696406009993	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
696406009994	active site
696406009995	hypothetical protein; Reviewed; Region: PRK01736
696406009996	Z-ring-associated protein; Provisional; Region: PRK10972
696406009997	5-formyltetrahydrofolate cyclo-ligase family protein; Provisional; Region: PRK10333
696406009998	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
696406009999	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
696406010000	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
696406010001	ligand binding site [chemical binding]; other site
696406010002	NAD binding site [chemical binding]; other site
696406010003	tetramer interface [polypeptide binding]; other site
696406010004	catalytic site [active]
696406010005	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
696406010006	L-serine binding site [chemical binding]; other site
696406010007	ACT domain interface; other site
696406010008	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
696406010009	tetramer (dimer of dimers) interface [polypeptide binding]; other site
696406010010	active site
696406010011	dimer interface [polypeptide binding]; other site
696406010012	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
696406010013	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
696406010014	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406010015	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
696406010016	putative dimerization interface [polypeptide binding]; other site
696406010017	methylmalonyl-CoA mutase; Reviewed; Region: PRK09426
696406010018	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, Alpha subunit-like subfamily; contains proteins similar to the alpha subunit of Propionbacterium shermanni MCM, as well as human and E. coli MCM. Members of this subfamily contain...; Region: MM_CoA_mutase_alpha_like; cd03679
696406010019	active site
696406010020	substrate binding site [chemical binding]; other site
696406010021	coenzyme B12 binding site [chemical binding]; other site
696406010022	methylmalonyl CoA mutase B12 binding domain. This domain binds to B12 (adenosylcobamide), which initiates the conversion of succinyl CoA and methylmalonyl CoA by forming an adenosyl radical, which then undergoes a rearrangement exchanging a hydrogen atom...; Region: MM_CoA_mut_B12_BD; cd02071
696406010023	B12 binding site [chemical binding]; other site
696406010024	cobalt ligand [ion binding]; other site
696406010025	membrane ATPase/protein kinase; Provisional; Region: PRK09435
696406010026	The function of this protein family is unkown. The protein sequences are similar to the ArgK protein in E. coli. ArgK protein is a membrane ATPase which is required for transporting arginine, ornithine and lysine into the cells by the arginine and...; Region: ArgK-like; cd03114
696406010027	Walker A; other site
696406010028	methylmalonyl-CoA decarboxylase; Provisional; Region: PRK11423
696406010029	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
696406010030	substrate binding site [chemical binding]; other site
696406010031	oxyanion hole (OAH) forming residues; other site
696406010032	trimer interface [polypeptide binding]; other site
696406010033	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
696406010034	succinate CoA transferase; Region: YgfH_subfam; TIGR03458
696406010035	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
696406010036	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406010037	Transcriptional regulator [Transcription]; Region: LysR; COG0583
696406010038	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
696406010039	dimerization interface [polypeptide binding]; other site
696406010040	Uncharacterized conserved protein [Function unknown]; Region: COG2968
696406010041	oxidative stress defense protein; Provisional; Region: PRK11087
696406010042	arginine exporter protein; Provisional; Region: PRK09304
696406010043	mechanosensitive channel MscS; Provisional; Region: PRK10334
696406010044	Mechanosensitive ion channel; Region: MS_channel; pfam00924
696406010045	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
696406010046	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
696406010047	active site
696406010048	intersubunit interface [polypeptide binding]; other site
696406010049	zinc binding site [ion binding]; other site
696406010050	Na+ binding site [ion binding]; other site
696406010051	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
696406010052	Phosphoglycerate kinase; Region: PGK; pfam00162
696406010053	substrate binding site [chemical binding]; other site
696406010054	hinge regions; other site
696406010055	ADP binding site [chemical binding]; other site
696406010056	catalytic site [active]
696406010057	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
696406010058	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
696406010059	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
696406010060	nucleoside triphosphate hydrolase domain-containing protein; Reviewed; Region: PRK09270
696406010061	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
696406010062	active site
696406010063	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
696406010064	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10022
696406010065	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
696406010066	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
696406010067	putative active site [active]
696406010068	L-sorbose-1-phosphate reductase; Region: sorbose_phosphate_red; cd08238
696406010069	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
696406010070	putative NAD(P) binding site [chemical binding]; other site
696406010071	catalytic Zn binding site [ion binding]; other site
696406010072	Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism]; Region: MtlA; COG2213
696406010073	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
696406010074	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
696406010075	active site
696406010076	P-loop; other site
696406010077	phosphorylation site [posttranslational modification]
696406010078	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
696406010079	active site
696406010080	phosphorylation site [posttranslational modification]
696406010081	transketolase; Reviewed; Region: PRK12753
696406010082	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
696406010083	TPP-binding site [chemical binding]; other site
696406010084	dimer interface [polypeptide binding]; other site
696406010085	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
696406010086	PYR/PP interface [polypeptide binding]; other site
696406010087	dimer interface [polypeptide binding]; other site
696406010088	TPP binding site [chemical binding]; other site
696406010089	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
696406010090	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
696406010091	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
696406010092	agmatinase; Region: agmatinase; TIGR01230
696406010093	oligomer interface [polypeptide binding]; other site
696406010094	putative active site [active]
696406010095	Mn binding site [ion binding]; other site
696406010096	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
696406010097	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
696406010098	dimer interface [polypeptide binding]; other site
696406010099	active site
696406010100	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
696406010101	catalytic residues [active]
696406010102	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
696406010103	Virulence promoting factor; Region: YqgB; pfam11036
696406010104	S-adenosylmethionine synthetase; Validated; Region: PRK05250
696406010105	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
696406010106	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
696406010107	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
696406010108	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
696406010109	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406010110	putative substrate translocation pore; other site
696406010111	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406010112	hypothetical protein; Provisional; Region: PRK04860
696406010113	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
696406010114	DNA-specific endonuclease I; Provisional; Region: PRK15137
696406010115	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
696406010116	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
696406010117	RNA methyltransferase, RsmE family; Region: TIGR00046
696406010118	glutathione synthetase; Provisional; Region: PRK05246
696406010119	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
696406010120	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
696406010121	hypothetical protein; Validated; Region: PRK00228
696406010122	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
696406010123	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
696406010124	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
696406010125	Walker A motif; other site
696406010126	ATP binding site [chemical binding]; other site
696406010127	Walker B motif; other site
696406010128	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
696406010129	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
696406010130	catalytic residue [active]
696406010131	YGGT family; Region: YGGT; pfam02325
696406010132	YGGT family; Region: YGGT; pfam02325
696406010133	hypothetical protein; Validated; Region: PRK05090
696406010134	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
696406010135	active site
696406010136	dimerization interface [polypeptide binding]; other site
696406010137	HemN family oxidoreductase; Provisional; Region: PRK05660
696406010138	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
696406010139	FeS/SAM binding site; other site
696406010140	HemN C-terminal domain; Region: HemN_C; pfam06969
696406010141	Protein of unknown function (DUF1202); Region: DUF1202; pfam06717
696406010142	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cd00411
696406010143	homodimer interface [polypeptide binding]; other site
696406010144	active site
696406010145	hypothetical protein; Provisional; Region: PRK10626
696406010146	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
696406010147	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
696406010148	hypothetical protein; Provisional; Region: PRK11702
696406010149	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
696406010150	adenine DNA glycosylase; Provisional; Region: PRK10880
696406010151	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
696406010152	minor groove reading motif; other site
696406010153	helix-hairpin-helix signature motif; other site
696406010154	substrate binding pocket [chemical binding]; other site
696406010155	active site
696406010156	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576
696406010157	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
696406010158	DNA binding and oxoG recognition site [nucleotide binding]
696406010159	oxidative damage protection protein; Provisional; Region: PRK05408
696406010160	murein transglycosylase C; Provisional; Region: mltC; PRK11671
696406010161	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
696406010162	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
696406010163	N-acetyl-D-glucosamine binding site [chemical binding]; other site
696406010164	catalytic residue [active]
696406010165	nucleoside transporter; Region: 2A0110; TIGR00889
696406010166	ornithine decarboxylase; Provisional; Region: PRK13578
696406010167	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
696406010168	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
696406010169	homodimer interface [polypeptide binding]; other site
696406010170	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406010171	catalytic residue [active]
696406010172	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
696406010173	Uncharacterized membrane protein, possible Na+ channel or pump [General function prediction only]; Region: COG1811
696406010174	integrase; Provisional; Region: PRK09692
696406010175	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
696406010176	active site
696406010177	Int/Topo IB signature motif; other site
696406010178	Protein of unknown function (DUF2931); Region: DUF2931; pfam11153
696406010179	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
696406010180	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
696406010181	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
696406010182	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
696406010183	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
696406010184	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
696406010185	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
696406010186	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
696406010187	Transposase; Region: HTH_Tnp_1; cl17663
696406010188	Integrase core domain; Region: rve; pfam00665
696406010189	Integrase core domain; Region: rve_3; pfam13683
696406010190	IS2 repressor TnpA; Reviewed; Region: PRK09413
696406010191	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
696406010192	Restriction endonuclease [Defense mechanisms]; Region: Mrr; COG1715
696406010193	Mrr N-terminal domain; Region: Mrr_N; pfam14338
696406010194	Restriction endonuclease; Region: Mrr_cat; pfam04471
696406010195	PLD-like domain; Region: PLDc_2; pfam13091
696406010196	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
696406010197	putative active site [active]
696406010198	catalytic site [active]
696406010199	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
696406010200	ATP binding site [chemical binding]; other site
696406010201	putative Mg++ binding site [ion binding]; other site
696406010202	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
696406010203	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
696406010204	nucleotide binding region [chemical binding]; other site
696406010205	ATP-binding site [chemical binding]; other site
696406010206	Protein of unknown function (DUF1156); Region: DUF1156; pfam06634
696406010207	Adenine-specific DNA methylase containing a Zn-ribbon [DNA replication, recombination, and repair]; Region: COG1743
696406010208	Protein of unknown function (DUF3780); Region: DUF3780; pfam12635
696406010209	Domain of unknown function (DUF4357); Region: DUF4357; pfam14267
696406010210	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1483
696406010211	Protein of unknown function (DUF499); Region: DUF499; pfam04465
696406010212	Chitobiase/beta-hexosaminidase C-terminal domain; Region: CHB_HEX_C; pfam03174
696406010213	Integrase core domain; Region: rve; pfam00665
696406010214	Integrase core domain; Region: rve_3; pfam13683
696406010215	McrBC 5-methylcytosine restriction system component; Region: McrBC; pfam10117
696406010216	AAA domain (dynein-related subfamily); Region: AAA_5; pfam07728
696406010217	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
696406010218	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
696406010219	Transposase; Region: HTH_Tnp_1; cl17663
696406010220	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
696406010221	putative transposase OrfB; Reviewed; Region: PHA02517
696406010222	HTH-like domain; Region: HTH_21; pfam13276
696406010223	Integrase core domain; Region: rve; pfam00665
696406010224	Integrase core domain; Region: rve_3; pfam13683
696406010225	Protein of unknown function (DUF2971); Region: DUF2971; pfam11185
696406010226	Predicted GTPase [General function prediction only]; Region: COG3596
696406010227	YfjP GTPase; Region: YfjP; cd11383
696406010228	G1 box; other site
696406010229	GTP/Mg2+ binding site [chemical binding]; other site
696406010230	Switch I region; other site
696406010231	G2 box; other site
696406010232	Switch II region; other site
696406010233	G3 box; other site
696406010234	G4 box; other site
696406010235	G5 box; other site
696406010236	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
696406010237	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
696406010238	hypothetical protein; Provisional; Region: PRK09945
696406010239	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
696406010240	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
696406010241	Autotransporter beta-domain; Region: Autotransporter; smart00869
696406010242	Bacterial protein of unknown function (DUF905); Region: DUF905; pfam06006
696406010243	Domain of unknown function (DUF932); Region: DUF932; pfam06067
696406010244	Antirestriction protein; Region: Antirestrict; pfam03230
696406010245	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
696406010246	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
696406010247	MPN+ (JAMM) motif; other site
696406010248	Zinc-binding site [ion binding]; other site
696406010249	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
696406010250	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
696406010251	Herpes virus major capsid protein; Region: Herpes_MCP; pfam03122
696406010252	Enterobacterial protein of unknown function (DUF957); Region: DUF957; pfam06117
696406010253	Methyltransferase domain; Region: Methyltransf_27; pfam13708
696406010254	putative general secretion pathway protein YghD; Provisional; Region: PRK09731
696406010255	type II secretion system protein L; Region: typeII_sec_gspL; TIGR01709
696406010256	GspL-like protein; Provisional; Region: PRK09662
696406010257	Type II secretion system (T2SS), protein K; Region: T2SK; pfam03934
696406010258	type II secretion system protein J; Region: gspJ; TIGR01711
696406010259	Type II secretion system (T2SS), protein J; Region: T2SJ; pfam11612
696406010260	type II secretion system protein I; Region: gspI; TIGR01707
696406010261	Type II secretion system (T2SS), protein I; Region: T2SI; pfam02501
696406010262	Type II transport protein GspH; Region: GspH; pfam12019
696406010263	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
696406010264	type II secretion system protein G; Region: typeII_sec_gspG; TIGR01710
696406010265	Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334
696406010266	type II secretion system protein F; Region: GspF; TIGR02120
696406010267	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
696406010268	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
696406010269	type II secretion system protein E; Region: type_II_gspE; TIGR02533
696406010270	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
696406010271	Walker A motif; other site
696406010272	ATP binding site [chemical binding]; other site
696406010273	Walker B motif; other site
696406010274	type II secretion system protein D; Region: type_II_gspD; TIGR02517
696406010275	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
696406010276	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
696406010277	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
696406010278	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
696406010279	putative type II secretion protein GspC; Provisional; Region: PRK09681
696406010280	Type IV pilus biogenesis; Region: Pilus_PilP; pfam11356
696406010281	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
696406010282	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
696406010283	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
696406010284	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
696406010285	Domain of unknown function (DUF4092); Region: DUF4092; pfam13322
696406010286	Peptidase M60-like family; Region: M60-like; pfam13402
696406010287	glycolate transporter; Provisional; Region: PRK09695
696406010288	L-lactate permease; Region: Lactate_perm; cl00701
696406010289	Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate...; Region: malate_synt_G; cd00728
696406010290	active site
696406010291	hypothetical protein; Provisional; Region: PRK09732
696406010292	glycolate oxidase iron-sulfur subunit; Provisional; Region: glcF; PRK11274
696406010293	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
696406010294	Cysteine-rich domain; Region: CCG; pfam02754
696406010295	Cysteine-rich domain; Region: CCG; pfam02754
696406010296	glycolate oxidase FAD binding subunit; Provisional; Region: glcE; PRK11282
696406010297	FAD binding domain; Region: FAD_binding_4; pfam01565
696406010298	glycolate oxidase subunit GlcD; Provisional; Region: PRK11230
696406010299	FAD binding domain; Region: FAD_binding_4; pfam01565
696406010300	DNA-binding transcriptional regulator GlcC; Provisional; Region: PRK09990
696406010301	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
696406010302	DNA-binding site [nucleotide binding]; DNA binding site
696406010303	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
696406010304	acyl-CoA synthetase; Validated; Region: PRK09192
696406010305	Fatty acyl-AMP ligase (FAAL); Region: FAAL; cd05931
696406010306	acyl-activating enzyme (AAE) consensus motif; other site
696406010307	active site
696406010308	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
696406010309	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
696406010310	NAD(P) binding site [chemical binding]; other site
696406010311	active site
696406010312	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
696406010313	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
696406010314	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
696406010315	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
696406010316	catalytic residue [active]
696406010317	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
696406010318	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
696406010319	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
696406010320	Predicted permeases [General function prediction only]; Region: COG0795
696406010321	Bacterial protein of unknown function (YtfJ_HI0045); Region: YtfJ_HI0045; pfam09695
696406010322	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
696406010323	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
696406010324	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
696406010325	Thymidylate kinase; Region: Thymidylate_kin; pfam02223
696406010326	active site
696406010327	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
696406010328	TMP-binding site; other site
696406010329	ATP-binding site [chemical binding]; other site
696406010330	Thymidylate kinase [Nucleotide transport and metabolism]; Region: Tmk; COG0125
696406010331	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
696406010332	TMP-binding site; other site
696406010333	ATP-binding site [chemical binding]; other site
696406010334	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
696406010335	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
696406010336	bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase; Provisional; Region: PRK10507
696406010337	CHAP domain; Region: CHAP; pfam05257
696406010338	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
696406010339	putative S-transferase; Provisional; Region: PRK11752
696406010340	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
696406010341	C-terminal domain interface [polypeptide binding]; other site
696406010342	GSH binding site (G-site) [chemical binding]; other site
696406010343	dimer interface [polypeptide binding]; other site
696406010344	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
696406010345	dimer interface [polypeptide binding]; other site
696406010346	N-terminal domain interface [polypeptide binding]; other site
696406010347	active site
696406010348	hydrogenase 2 accessory protein HypG; Provisional; Region: PRK10413
696406010349	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
696406010350	hydrogenase nickel incorporation protein HybF; Provisional; Region: PRK12380
696406010351	hydrogenase 2-specific chaperone; Provisional; Region: PRK10465
696406010352	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
696406010353	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
696406010354	putative substrate-binding site; other site
696406010355	nickel binding site [ion binding]; other site
696406010356	hydrogenase 2 large subunit; Provisional; Region: PRK10467
696406010357	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
696406010358	putative hydrogenase 2 b cytochrome subunit; Provisional; Region: PRK10881
696406010359	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
696406010360	hydrogenase 2 protein HybA; Provisional; Region: PRK10882
696406010361	4Fe-4S binding domain; Region: Fer4_6; pfam12837
696406010362	hydrogenase 2 small subunit; Provisional; Region: PRK10468
696406010363	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
696406010364	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
696406010365	Protein of unknown function (DUF2623); Region: DUF2623; pfam11115
696406010366	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
696406010367	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
696406010368	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
696406010369	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
696406010370	active site
696406010371	catalytic tetrad [active]
696406010372	hypothetical protein; Provisional; Region: PRK05208
696406010373	oxidoreductase; Provisional; Region: PRK07985
696406010374	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
696406010375	NAD binding site [chemical binding]; other site
696406010376	metal binding site [ion binding]; metal-binding site
696406010377	active site
696406010378	biopolymer transport protein ExbD; Provisional; Region: PRK11267
696406010379	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
696406010380	biopolymer transport protein ExbB; Provisional; Region: PRK10414
696406010381	cystathionine beta-lyase; Provisional; Region: PRK08114
696406010382	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
696406010383	homodimer interface [polypeptide binding]; other site
696406010384	substrate-cofactor binding pocket; other site
696406010385	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406010386	catalytic residue [active]
696406010387	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
696406010388	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
696406010389	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
696406010390	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
696406010391	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406010392	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406010393	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
696406010394	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
696406010395	dimer interface [polypeptide binding]; other site
696406010396	active site
696406010397	metal binding site [ion binding]; metal-binding site
696406010398	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
696406010399	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
696406010400	active site
696406010401	catalytic tetrad [active]
696406010402	Protein of unknown function (DUF3828); Region: DUF3828; pfam12883
696406010403	putative outer membrane lipoprotein; Provisional; Region: PRK09973
696406010404	hypothetical protein; Provisional; Region: PRK01254
696406010405	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
696406010406	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
696406010407	FtsI repressor; Provisional; Region: PRK10883
696406010408	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
696406010409	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
696406010410	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
696406010411	putative acyl-acceptor binding pocket; other site
696406010412	DNA topoisomerase IV, A subunit, proteobacterial; Region: parC_Gneg; TIGR01062
696406010413	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
696406010414	CAP-like domain; other site
696406010415	active site
696406010416	primary dimer interface [polypeptide binding]; other site
696406010417	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
696406010418	putative ABC transporter periplasmic-binding protein; Provisional; Region: PRK09755
696406010419	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
696406010420	peptide binding site [polypeptide binding]; other site
696406010421	antitoxin MqsA for MqsR toxin; Region: MqsA; cd12870
696406010422	toxin interface [polypeptide binding]; other site
696406010423	putative zinc finger/helix-turn-helix protein, YgiT family; Region: CxxCG_CxxCG_HTH; TIGR03830
696406010424	Zn binding site [ion binding]; other site
696406010425	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
696406010426	non-specific DNA binding site [nucleotide binding]; other site
696406010427	salt bridge; other site
696406010428	sequence-specific DNA binding site [nucleotide binding]; other site
696406010429	DNA gyrase inhibitor [DNA replication, recombination, and repair]; Region: COG3449
696406010430	TIGR00156 family protein; Region: TIGR00156
696406010431	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
696406010432	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406010433	active site
696406010434	phosphorylation site [posttranslational modification]
696406010435	intermolecular recognition site; other site
696406010436	dimerization interface [polypeptide binding]; other site
696406010437	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
696406010438	DNA binding site [nucleotide binding]
696406010439	sensor protein QseC; Provisional; Region: PRK10337
696406010440	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
696406010441	dimer interface [polypeptide binding]; other site
696406010442	phosphorylation site [posttranslational modification]
696406010443	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406010444	ATP binding site [chemical binding]; other site
696406010445	Mg2+ binding site [ion binding]; other site
696406010446	G-X-G motif; other site
696406010447	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
696406010448	Uncharacterized conserved protein [Function unknown]; Region: COG1359
696406010449	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
696406010450	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406010451	ATP binding site [chemical binding]; other site
696406010452	Mg2+ binding site [ion binding]; other site
696406010453	G-X-G motif; other site
696406010454	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
696406010455	anchoring element; other site
696406010456	dimer interface [polypeptide binding]; other site
696406010457	ATP binding site [chemical binding]; other site
696406010458	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
696406010459	active site
696406010460	metal binding site [ion binding]; metal-binding site
696406010461	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
696406010462	esterase YqiA; Provisional; Region: PRK11071
696406010463	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
696406010464	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
696406010465	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
696406010466	active site
696406010467	metal binding site [ion binding]; metal-binding site
696406010468	hexamer interface [polypeptide binding]; other site
696406010469	putative dehydrogenase; Provisional; Region: PRK11039
696406010470	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
696406010471	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
696406010472	dimer interface [polypeptide binding]; other site
696406010473	ADP-ribose binding site [chemical binding]; other site
696406010474	active site
696406010475	nudix motif; other site
696406010476	metal binding site [ion binding]; metal-binding site
696406010477	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
696406010478	hypothetical protein; Provisional; Region: PRK11653
696406010479	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
696406010480	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
696406010481	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
696406010482	putative active site [active]
696406010483	metal binding site [ion binding]; metal-binding site
696406010484	zinc transporter ZupT; Provisional; Region: PRK04201
696406010485	ZIP Zinc transporter; Region: Zip; pfam02535
696406010486	Protein of unknown function (DUF4051); Region: DUF4051; pfam13260
696406010487	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
696406010488	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
696406010489	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
696406010490	putative fimbrial protein; Provisional; Region: PRK09733
696406010491	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
696406010492	PapC N-terminal domain; Region: PapC_N; pfam13954
696406010493	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
696406010494	PapC C-terminal domain; Region: PapC_C; pfam13953
696406010495	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
696406010496	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
696406010497	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
696406010498	Fimbrial protein; Region: Fimbrial; pfam00419
696406010499	glycogen synthesis protein GlgS; Provisional; Region: PRK02922
696406010500	Protein of unknown function (DUF1449); Region: DUF1449; pfam07290
696406010501	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
696406010502	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
696406010503	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
696406010504	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
696406010505	putative ribose interaction site [chemical binding]; other site
696406010506	putative ADP binding site [chemical binding]; other site
696406010507	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
696406010508	active site
696406010509	nucleotide binding site [chemical binding]; other site
696406010510	HIGH motif; other site
696406010511	KMSKS motif; other site
696406010512	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
696406010513	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
696406010514	metal binding triad; other site
696406010515	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
696406010516	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
696406010517	metal binding triad; other site
696406010518	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
696406010519	Uncharacterized conserved protein [Function unknown]; Region: COG3025
696406010520	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
696406010521	putative active site [active]
696406010522	putative metal binding residues [ion binding]; other site
696406010523	signature motif; other site
696406010524	putative triphosphate binding site [ion binding]; other site
696406010525	CHAD domain; Region: CHAD; pfam05235
696406010526	SH3 domain-containing protein; Provisional; Region: PRK10884
696406010527	Bacterial SH3 domain homologues; Region: SH3b; smart00287
696406010528	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
696406010529	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
696406010530	active site
696406010531	NTP binding site [chemical binding]; other site
696406010532	metal binding triad [ion binding]; metal-binding site
696406010533	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
696406010534	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
696406010535	Zn2+ binding site [ion binding]; other site
696406010536	Mg2+ binding site [ion binding]; other site
696406010537	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
696406010538	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
696406010539	homooctamer interface [polypeptide binding]; other site
696406010540	active site
696406010541	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
696406010542	transcriptional activator TtdR; Provisional; Region: PRK09801
696406010543	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406010544	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
696406010545	putative effector binding pocket; other site
696406010546	putative dimerization interface [polypeptide binding]; other site
696406010547	tartrate dehydratase subunit alpha; Validated; Region: PRK08230
696406010548	L(+)-tartrate dehydratase subunit beta; Validated; Region: PRK08228
696406010549	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
696406010550	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
696406010551	transmembrane helices; other site
696406010552	UGMP family protein; Validated; Region: PRK09604
696406010553	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
696406010554	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
696406010555	DNA primase; Validated; Region: dnaG; PRK05667
696406010556	CHC2 zinc finger; Region: zf-CHC2; pfam01807
696406010557	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
696406010558	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
696406010559	active site
696406010560	metal binding site [ion binding]; metal-binding site
696406010561	interdomain interaction site; other site
696406010562	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
696406010563	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
696406010564	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
696406010565	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
696406010566	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
696406010567	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
696406010568	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
696406010569	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
696406010570	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
696406010571	DNA binding residues [nucleotide binding]
696406010572	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
696406010573	active site
696406010574	SUMO-1 interface [polypeptide binding]; other site
696406010575	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
696406010576	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
696406010577	FAD binding pocket [chemical binding]; other site
696406010578	FAD binding motif [chemical binding]; other site
696406010579	phosphate binding motif [ion binding]; other site
696406010580	NAD binding pocket [chemical binding]; other site
696406010581	Predicted transcriptional regulators [Transcription]; Region: COG1695
696406010582	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
696406010583	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
696406010584	PAS fold; Region: PAS_3; pfam08447
696406010585	putative active site [active]
696406010586	heme pocket [chemical binding]; other site
696406010587	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
696406010588	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
696406010589	dimer interface [polypeptide binding]; other site
696406010590	putative CheW interface [polypeptide binding]; other site
696406010591	putrescine--2-oxoglutarate aminotransferase; Provisional; Region: PRK11522
696406010592	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
696406010593	inhibitor-cofactor binding pocket; inhibition site
696406010594	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406010595	catalytic residue [active]
696406010596	tRNA-binding-domain-containing CsaA-like proteins. CsaA is a molecular chaperone with export related activities. CsaA has a putative tRNA binding activity. The functional unit of CsaA is a homodimer and this domain acts as a dimerization domain; Region: tRNA_bind_CsaA; cd02798
696406010597	dimer interface [polypeptide binding]; other site
696406010598	putative tRNA-binding site [nucleotide binding]; other site
696406010599	DNA-binding transcriptional repressor EbgR; Provisional; Region: PRK10339
696406010600	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
696406010601	DNA binding site [nucleotide binding]
696406010602	domain linker motif; other site
696406010603	Ligand-binding domain of DNA transcription repressor GalR which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalR; cd01544
696406010604	putative dimerization interface [polypeptide binding]; other site
696406010605	putative ligand binding site [chemical binding]; other site
696406010606	cryptic beta-D-galactosidase subunit alpha; Reviewed; Region: ebgA; PRK10340
696406010607	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
696406010608	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
696406010609	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
696406010610	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
696406010611	cryptic beta-D-galactosidase subunit beta; Reviewed; Region: ebgC; PRK10202
696406010612	inner membrane transporter YjeM; Provisional; Region: PRK15238
696406010613	alpha-glucosidase; Provisional; Region: PRK10137
696406010614	Protein of unknown function, DUF608; Region: DUF608; pfam04685
696406010615	Trehalase; Region: Trehalase; cl17346
696406010616	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
696406010617	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
696406010618	active site
696406010619	FMN binding site [chemical binding]; other site
696406010620	2,4-decadienoyl-CoA binding site; other site
696406010621	catalytic residue [active]
696406010622	4Fe-4S cluster binding site [ion binding]; other site
696406010623	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
696406010624	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
696406010625	non-specific DNA binding site [nucleotide binding]; other site
696406010626	salt bridge; other site
696406010627	sequence-specific DNA binding site [nucleotide binding]; other site
696406010628	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4680
696406010629	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
696406010630	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406010631	S-adenosylmethionine binding site [chemical binding]; other site
696406010632	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
696406010633	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
696406010634	putative active site [active]
696406010635	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
696406010636	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
696406010637	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
696406010638	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
696406010639	serine/threonine transporter SstT; Provisional; Region: PRK13628
696406010640	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
696406010641	Bacterial inner membrane protein; Region: Imp-YgjV; pfam10688
696406010642	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
696406010643	galactarate dehydratase; Region: galactar-dH20; TIGR03248
696406010644	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
696406010645	Glucuronate isomerase; Region: UxaC; pfam02614
696406010646	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
696406010647	D-galactonate transporter; Region: 2A0114; TIGR00893
696406010648	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406010649	putative substrate translocation pore; other site
696406010650	DNA-binding transcriptional repressor ExuR; Provisional; Region: PRK11523
696406010651	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
696406010652	DNA-binding site [nucleotide binding]; DNA binding site
696406010653	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
696406010654	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
696406010655	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
696406010656	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
696406010657	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
696406010658	Uncharacterized conserved protein [Function unknown]; Region: ElaB; COG4575
696406010659	Predicted membrane protein [Function unknown]; Region: COG5393
696406010660	YqjK-like protein; Region: YqjK; pfam13997
696406010661	Predicted membrane protein [Function unknown]; Region: COG2259
696406010662	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
696406010663	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
696406010664	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
696406010665	putative dimer interface [polypeptide binding]; other site
696406010666	N-terminal domain interface [polypeptide binding]; other site
696406010667	putative substrate binding pocket (H-site) [chemical binding]; other site
696406010668	Predicted membrane protein [Function unknown]; Region: COG3152
696406010669	Predicted membrane protein [Function unknown]; Region: COG3152
696406010670	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406010671	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
696406010672	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
696406010673	dimerization interface [polypeptide binding]; other site
696406010674	Pirin; Region: Pirin; pfam02678
696406010675	Pirin-related protein [General function prediction only]; Region: COG1741
696406010676	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
696406010677	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
696406010678	serine transporter; Region: stp; TIGR00814
696406010679	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
696406010680	L-serine deaminase [Amino acid transport and metabolism]; Region: SdaA; COG1760
696406010681	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
696406010682	homotrimer interaction site [polypeptide binding]; other site
696406010683	putative active site [active]
696406010684	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
696406010685	Pyruvate formate lyase 1; Region: PFL1; cd01678
696406010686	coenzyme A binding site [chemical binding]; other site
696406010687	active site
696406010688	catalytic residues [active]
696406010689	glycine loop; other site
696406010690	propionate/acetate kinase; Provisional; Region: PRK12379
696406010691	acetate kinase; Region: ackA; TIGR00016
696406010692	threonine/serine transporter TdcC; Provisional; Region: PRK13629
696406010693	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
696406010694	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
696406010695	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
696406010696	tetramer interface [polypeptide binding]; other site
696406010697	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406010698	catalytic residue [active]
696406010699	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
696406010700	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406010701	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
696406010702	putative substrate binding pocket [chemical binding]; other site
696406010703	putative dimerization interface [polypeptide binding]; other site
696406010704	DNA-binding transcriptional activator TdcR; Provisional; Region: PRK11424
696406010705	glycerate kinase I; Provisional; Region: PRK10342
696406010706	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
696406010707	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
696406010708	alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional; Region: PRK10558
696406010709	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406010710	D-galactonate transporter; Region: 2A0114; TIGR00893
696406010711	putative substrate translocation pore; other site
696406010712	galactarate dehydratase; Region: galactar-dH20; TIGR03248
696406010713	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
696406010714	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
696406010715	Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877
696406010716	Toxin with endonuclease activity YhaV; Region: Toxin_YhaV; pfam11663
696406010717	DNA-binding transcriptional regulator AgaR; Provisional; Region: PRK09802
696406010718	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
696406010719	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
696406010720	tagatose 6-phosphate aldolase subunit KbaZ; Provisional; Region: PRK15458
696406010721	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
696406010722	active site
696406010723	phosphorylation site [posttranslational modification]
696406010724	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
696406010725	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
696406010726	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
696406010727	active pocket/dimerization site; other site
696406010728	active site
696406010729	phosphorylation site [posttranslational modification]
696406010730	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
696406010731	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
696406010732	active site
696406010733	dimer interface [polypeptide binding]; other site
696406010734	putative sugar isomerase, AgaS family; Region: agaS_fam; TIGR02815
696406010735	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
696406010736	dimer interface [polypeptide binding]; other site
696406010737	active site
696406010738	AgaS-like protein. AgaS contains a SIS (Sugar ISomerase) domain which is found in many phosphosugar isomerases and phosphosugar binding proteins. AgaS is a putative isomerase in Escherichia coli. It is similar to the glucosamine-6-phosphate synthases; Region: SIS_AgaS_like; cd05010
696406010739	putative active site [active]
696406010740	Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the...; Region: FTBP_aldolase_II; cd00453
696406010741	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
696406010742	active site
696406010743	intersubunit interface [polypeptide binding]; other site
696406010744	zinc binding site [ion binding]; other site
696406010745	Na+ binding site [ion binding]; other site
696406010746	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
696406010747	active site
696406010748	phosphorylation site [posttranslational modification]
696406010749	PTS system N-acetylgalactosamine-specific transporter subunit IIC; Provisional; Region: PRK09757
696406010750	PTS system N-acetylgalactosamine-specific transporter subunit IID; Provisional; Region: PRK09855
696406010751	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
696406010752	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
696406010753	active site
696406010754	trimer interface [polypeptide binding]; other site
696406010755	allosteric site; other site
696406010756	active site lid [active]
696406010757	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
696406010758	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
696406010759	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
696406010760	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
696406010761	Fimbrial protein; Region: Fimbrial; pfam00419
696406010762	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
696406010763	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
696406010764	putative SAM binding site [chemical binding]; other site
696406010765	putative homodimer interface [polypeptide binding]; other site
696406010766	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
696406010767	Putative lipoprotein [General function prediction only]; Region: LppC; COG3107
696406010768	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
696406010769	putative ligand binding site [chemical binding]; other site
696406010770	TIGR00252 family protein; Region: TIGR00252
696406010771	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
696406010772	dimer interface [polypeptide binding]; other site
696406010773	active site
696406010774	outer membrane lipoprotein; Provisional; Region: PRK11023
696406010775	BON domain; Region: BON; pfam04972
696406010776	BON domain; Region: BON; pfam04972
696406010777	Predicted permease; Region: DUF318; pfam03773
696406010778	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
696406010779	NADH(P)-binding; Region: NAD_binding_10; pfam13460
696406010780	NAD binding site [chemical binding]; other site
696406010781	active site
696406010782	intracellular protease, PfpI family; Region: PfpI; TIGR01382
696406010783	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
696406010784	proposed catalytic triad [active]
696406010785	conserved cys residue [active]
696406010786	hypothetical protein; Provisional; Region: PRK03467
696406010787	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
696406010788	putative active site [active]
696406010789	GIY-YIG motif/motif A; other site
696406010790	putative metal binding site [ion binding]; other site
696406010791	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
696406010792	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
696406010793	Coenzyme A binding pocket [chemical binding]; other site
696406010794	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
696406010795	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
696406010796	Peptidase family U32; Region: Peptidase_U32; pfam01136
696406010797	putative protease; Provisional; Region: PRK15447
696406010798	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
696406010799	hypothetical protein; Provisional; Region: PRK10508
696406010800	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
696406010801	tryptophan permease; Provisional; Region: PRK10483
696406010802	aromatic amino acid transport protein; Region: araaP; TIGR00837
696406010803	ATP-dependent RNA helicase DeaD; Provisional; Region: PRK11634
696406010804	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
696406010805	ATP binding site [chemical binding]; other site
696406010806	Mg++ binding site [ion binding]; other site
696406010807	motif III; other site
696406010808	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
696406010809	nucleotide binding region [chemical binding]; other site
696406010810	ATP-binding site [chemical binding]; other site
696406010811	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
696406010812	putative RNA binding site [nucleotide binding]; other site
696406010813	lipoprotein NlpI; Provisional; Region: PRK11189
696406010814	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
696406010815	binding surface
696406010816	TPR motif; other site
696406010817	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
696406010818	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
696406010819	RNase E interface [polypeptide binding]; other site
696406010820	trimer interface [polypeptide binding]; other site
696406010821	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
696406010822	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
696406010823	RNase E interface [polypeptide binding]; other site
696406010824	trimer interface [polypeptide binding]; other site
696406010825	active site
696406010826	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
696406010827	putative nucleic acid binding region [nucleotide binding]; other site
696406010828	G-X-X-G motif; other site
696406010829	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
696406010830	RNA binding site [nucleotide binding]; other site
696406010831	domain interface; other site
696406010832	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
696406010833	16S/18S rRNA binding site [nucleotide binding]; other site
696406010834	S13e-L30e interaction site [polypeptide binding]; other site
696406010835	25S rRNA binding site [nucleotide binding]; other site
696406010836	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
696406010837	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
696406010838	RNA binding site [nucleotide binding]; other site
696406010839	active site
696406010840	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
696406010841	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
696406010842	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
696406010843	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
696406010844	translation initiation factor IF-2; Region: IF-2; TIGR00487
696406010845	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
696406010846	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
696406010847	G1 box; other site
696406010848	putative GEF interaction site [polypeptide binding]; other site
696406010849	GTP/Mg2+ binding site [chemical binding]; other site
696406010850	Switch I region; other site
696406010851	G2 box; other site
696406010852	G3 box; other site
696406010853	Switch II region; other site
696406010854	G4 box; other site
696406010855	G5 box; other site
696406010856	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
696406010857	Translation-initiation factor 2; Region: IF-2; pfam11987
696406010858	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
696406010859	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
696406010860	NusA N-terminal domain; Region: NusA_N; pfam08529
696406010861	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
696406010862	RNA binding site [nucleotide binding]; other site
696406010863	homodimer interface [polypeptide binding]; other site
696406010864	NusA-like KH domain; Region: KH_5; pfam13184
696406010865	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
696406010866	G-X-X-G motif; other site
696406010867	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
696406010868	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
696406010869	ribosome maturation protein RimP; Reviewed; Region: PRK00092
696406010870	hypothetical protein; Provisional; Region: PRK14641
696406010871	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
696406010872	putative oligomer interface [polypeptide binding]; other site
696406010873	putative RNA binding site [nucleotide binding]; other site
696406010874	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
696406010875	ANP binding site [chemical binding]; other site
696406010876	Substrate Binding Site II [chemical binding]; other site
696406010877	Substrate Binding Site I [chemical binding]; other site
696406010878	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
696406010879	Sulfatase; Region: Sulfatase; pfam00884
696406010880	Preprotein translocase SecG subunit; Region: SecG; pfam03840
696406010881	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
696406010882	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
696406010883	active site
696406010884	substrate binding site [chemical binding]; other site
696406010885	metal binding site [ion binding]; metal-binding site
696406010886	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
696406010887	dihydropteroate synthase; Region: DHPS; TIGR01496
696406010888	substrate binding pocket [chemical binding]; other site
696406010889	dimer interface [polypeptide binding]; other site
696406010890	inhibitor binding site; inhibition site
696406010891	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
696406010892	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406010893	Walker A motif; other site
696406010894	ATP binding site [chemical binding]; other site
696406010895	Walker B motif; other site
696406010896	arginine finger; other site
696406010897	Peptidase family M41; Region: Peptidase_M41; pfam01434
696406010898	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
696406010899	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406010900	S-adenosylmethionine binding site [chemical binding]; other site
696406010901	RNA-binding protein YhbY; Provisional; Region: PRK10343
696406010902	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
696406010903	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
696406010904	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
696406010905	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
696406010906	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
696406010907	GTPase CgtA; Reviewed; Region: obgE; PRK12298
696406010908	GTP1/OBG; Region: GTP1_OBG; pfam01018
696406010909	Obg GTPase; Region: Obg; cd01898
696406010910	G1 box; other site
696406010911	GTP/Mg2+ binding site [chemical binding]; other site
696406010912	Switch I region; other site
696406010913	G2 box; other site
696406010914	G3 box; other site
696406010915	Switch II region; other site
696406010916	G4 box; other site
696406010917	G5 box; other site
696406010918	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
696406010919	EamA-like transporter family; Region: EamA; pfam00892
696406010920	EamA-like transporter family; Region: EamA; pfam00892
696406010921	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
696406010922	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
696406010923	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
696406010924	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
696406010925	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
696406010926	substrate binding pocket [chemical binding]; other site
696406010927	chain length determination region; other site
696406010928	substrate-Mg2+ binding site; other site
696406010929	catalytic residues [active]
696406010930	aspartate-rich region 1; other site
696406010931	active site lid residues [active]
696406010932	aspartate-rich region 2; other site
696406010933	DNA-binding transcriptional regulator Nlp; Provisional; Region: PRK10344
696406010934	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
696406010935	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
696406010936	hinge; other site
696406010937	active site
696406010938	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
696406010939	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
696406010940	anti sigma factor interaction site; other site
696406010941	regulatory phosphorylation site [posttranslational modification]; other site
696406010942	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
696406010943	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
696406010944	mce related protein; Region: MCE; pfam02470
696406010945	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
696406010946	conserved hypothetical integral membrane protein; Region: TIGR00056
696406010947	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
696406010948	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
696406010949	Walker A/P-loop; other site
696406010950	ATP binding site [chemical binding]; other site
696406010951	Q-loop/lid; other site
696406010952	ABC transporter signature motif; other site
696406010953	Walker B; other site
696406010954	D-loop; other site
696406010955	H-loop/switch region; other site
696406010956	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
696406010957	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
696406010958	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
696406010959	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
696406010960	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
696406010961	putative active site [active]
696406010962	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
696406010963	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
696406010964	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
696406010965	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
696406010966	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
696406010967	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
696406010968	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
696406010969	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
696406010970	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
696406010971	Walker A/P-loop; other site
696406010972	ATP binding site [chemical binding]; other site
696406010973	Q-loop/lid; other site
696406010974	ABC transporter signature motif; other site
696406010975	Walker B; other site
696406010976	D-loop; other site
696406010977	H-loop/switch region; other site
696406010978	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
696406010979	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
696406010980	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
696406010981	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
696406010982	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
696406010983	30S subunit binding site; other site
696406010984	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
696406010985	active site
696406010986	phosphorylation site [posttranslational modification]
696406010987	P-loop ATPase protein family; Region: ATP_bind_2; pfam03668
696406010988	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
696406010989	dimerization domain swap beta strand [polypeptide binding]; other site
696406010990	regulatory protein interface [polypeptide binding]; other site
696406010991	active site
696406010992	regulatory phosphorylation site [posttranslational modification]; other site
696406010993	hypothetical protein; Provisional; Region: PRK10345
696406010994	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
696406010995	Transglycosylase; Region: Transgly; cl17702
696406010996	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
696406010997	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
696406010998	conserved cys residue [active]
696406010999	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
696406011000	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
696406011001	putative active site [active]
696406011002	heme pocket [chemical binding]; other site
696406011003	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
696406011004	dimer interface [polypeptide binding]; other site
696406011005	phosphorylation site [posttranslational modification]
696406011006	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406011007	ATP binding site [chemical binding]; other site
696406011008	Mg2+ binding site [ion binding]; other site
696406011009	G-X-G motif; other site
696406011010	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406011011	active site
696406011012	phosphorylation site [posttranslational modification]
696406011013	intermolecular recognition site; other site
696406011014	dimerization interface [polypeptide binding]; other site
696406011015	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
696406011016	putative binding surface; other site
696406011017	active site
696406011018	radical SAM protein, TIGR01212 family; Region: TIGR01212
696406011019	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
696406011020	FeS/SAM binding site; other site
696406011021	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
696406011022	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
696406011023	active site
696406011024	dimer interface [polypeptide binding]; other site
696406011025	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
696406011026	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
696406011027	active site
696406011028	FMN binding site [chemical binding]; other site
696406011029	substrate binding site [chemical binding]; other site
696406011030	3Fe-4S cluster binding site [ion binding]; other site
696406011031	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
696406011032	domain interface; other site
696406011033	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
696406011034	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
696406011035	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
696406011036	Protein of unknown function (DUF1120); Region: DUF1120; pfam06551
696406011037	putative fimbrial chaperone protein; Provisional; Region: PRK09918
696406011038	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
696406011039	putative fimbrial outer membrane usher protein; Provisional; Region: PRK15304
696406011040	PapC N-terminal domain; Region: PapC_N; pfam13954
696406011041	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
696406011042	PapC C-terminal domain; Region: PapC_C; pfam13953
696406011043	hypothetical protein; Provisional; Region: PRK15301
696406011044	Protein of unknown function (DUF1120); Region: DUF1120; pfam06551
696406011045	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
696406011046	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
696406011047	uncharacterized protein, YhcH/YjgK/YiaL family; Region: TIGR00022
696406011048	N-acetylmannosamine kinase; Provisional; Region: PRK05082
696406011049	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
696406011050	nucleotide binding site [chemical binding]; other site
696406011051	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
696406011052	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
696406011053	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
696406011054	putative active site cavity [active]
696406011055	putative sialic acid transporter; Provisional; Region: PRK03893
696406011056	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406011057	putative substrate translocation pore; other site
696406011058	N-acetylneuraminate lyase; Region: nanA; TIGR00683
696406011059	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
696406011060	inhibitor site; inhibition site
696406011061	active site
696406011062	dimer interface [polypeptide binding]; other site
696406011063	catalytic residue [active]
696406011064	transcriptional regulator NanR; Provisional; Region: PRK03837
696406011065	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
696406011066	DNA-binding site [nucleotide binding]; DNA binding site
696406011067	FCD domain; Region: FCD; pfam07729
696406011068	putative cryptic C4-dicarboxylate transporter DcuD; Provisional; Region: PRK09804
696406011069	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
696406011070	ClpXP protease specificity-enhancing factor; Provisional; Region: PRK11798
696406011071	stringent starvation protein A; Provisional; Region: sspA; PRK09481
696406011072	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
696406011073	C-terminal domain interface [polypeptide binding]; other site
696406011074	putative GSH binding site (G-site) [chemical binding]; other site
696406011075	dimer interface [polypeptide binding]; other site
696406011076	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
696406011077	dimer interface [polypeptide binding]; other site
696406011078	N-terminal domain interface [polypeptide binding]; other site
696406011079	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
696406011080	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
696406011081	23S rRNA interface [nucleotide binding]; other site
696406011082	L3 interface [polypeptide binding]; other site
696406011083	Predicted ATPase [General function prediction only]; Region: COG1485
696406011084	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
696406011085	hypothetical protein; Provisional; Region: PRK11677
696406011086	serine endoprotease; Provisional; Region: PRK10139
696406011087	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
696406011088	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
696406011089	protein binding site [polypeptide binding]; other site
696406011090	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
696406011091	serine endoprotease; Provisional; Region: PRK10898
696406011092	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
696406011093	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
696406011094	malate dehydrogenase; Provisional; Region: PRK05086
696406011095	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
696406011096	NAD binding site [chemical binding]; other site
696406011097	dimerization interface [polypeptide binding]; other site
696406011098	Substrate binding site [chemical binding]; other site
696406011099	arginine repressor; Provisional; Region: PRK05066
696406011100	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
696406011101	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
696406011102	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
696406011103	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
696406011104	RNAase interaction site [polypeptide binding]; other site
696406011105	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
696406011106	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
696406011107	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
696406011108	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
696406011109	HlyD family secretion protein; Region: HlyD_3; pfam13437
696406011110	efflux system membrane protein; Provisional; Region: PRK11594
696406011111	transcriptional regulator; Provisional; Region: PRK10632
696406011112	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406011113	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
696406011114	putative effector binding pocket; other site
696406011115	dimerization interface [polypeptide binding]; other site
696406011116	protease TldD; Provisional; Region: tldD; PRK10735
696406011117	hypothetical protein; Provisional; Region: PRK10899
696406011118	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
696406011119	ribonuclease G; Provisional; Region: PRK11712
696406011120	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
696406011121	homodimer interface [polypeptide binding]; other site
696406011122	oligonucleotide binding site [chemical binding]; other site
696406011123	Maf-like protein; Region: Maf; pfam02545
696406011124	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
696406011125	active site
696406011126	dimer interface [polypeptide binding]; other site
696406011127	rod shape-determining protein MreD; Provisional; Region: PRK11060
696406011128	rod shape-determining protein MreC; Region: mreC; TIGR00219
696406011129	rod shape-determining protein MreC; Region: MreC; pfam04085
696406011130	rod shape-determining protein MreB; Provisional; Region: PRK13927
696406011131	MreB and similar proteins; Region: MreB_like; cd10225
696406011132	nucleotide binding site [chemical binding]; other site
696406011133	Mg binding site [ion binding]; other site
696406011134	putative protofilament interaction site [polypeptide binding]; other site
696406011135	RodZ interaction site [polypeptide binding]; other site
696406011136	regulatory protein CsrD; Provisional; Region: PRK11059
696406011137	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
696406011138	metal binding site [ion binding]; metal-binding site
696406011139	active site
696406011140	I-site; other site
696406011141	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
696406011142	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
696406011143	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
696406011144	NADP binding site [chemical binding]; other site
696406011145	dimer interface [polypeptide binding]; other site
696406011146	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
696406011147	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
696406011148	carboxyltransferase (CT) interaction site; other site
696406011149	biotinylation site [posttranslational modification]; other site
696406011150	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
696406011151	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
696406011152	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
696406011153	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
696406011154	hypothetical protein; Provisional; Region: PRK10633
696406011155	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
696406011156	Na binding site [ion binding]; other site
696406011157	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
696406011158	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
696406011159	Dihydrouridine synthase (Dus); Region: Dus; pfam01207
696406011160	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
696406011161	FMN binding site [chemical binding]; other site
696406011162	active site
696406011163	catalytic residues [active]
696406011164	substrate binding site [chemical binding]; other site
696406011165	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
696406011166	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
696406011167	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
696406011168	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406011169	DNA methylase; Region: N6_N4_Mtase; pfam01555
696406011170	Protein of unknown function (DUF2556); Region: DUF2556; pfam10831
696406011171	DNA-binding transcriptional regulator EnvR; Provisional; Region: PRK09975
696406011172	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
696406011173	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
696406011174	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
696406011175	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
696406011176	HlyD family secretion protein; Region: HlyD_3; pfam13437
696406011177	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
696406011178	Protein export membrane protein; Region: SecD_SecF; cl14618
696406011179	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
696406011180	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
696406011181	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
696406011182	substrate binding pocket [chemical binding]; other site
696406011183	membrane-bound complex binding site; other site
696406011184	hinge residues; other site
696406011185	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: BatB; COG4597
696406011186	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406011187	conserved gate region; other site
696406011188	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406011189	dimer interface [polypeptide binding]; other site
696406011190	conserved gate region; other site
696406011191	putative PBP binding loops; other site
696406011192	ABC-ATPase subunit interface; other site
696406011193	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
696406011194	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406011195	dimer interface [polypeptide binding]; other site
696406011196	conserved gate region; other site
696406011197	putative PBP binding loops; other site
696406011198	ABC-ATPase subunit interface; other site
696406011199	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
696406011200	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
696406011201	Walker A/P-loop; other site
696406011202	ATP binding site [chemical binding]; other site
696406011203	Q-loop/lid; other site
696406011204	ABC transporter signature motif; other site
696406011205	Walker B; other site
696406011206	D-loop; other site
696406011207	H-loop/switch region; other site
696406011208	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
696406011209	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
696406011210	trimer interface [polypeptide binding]; other site
696406011211	putative metal binding site [ion binding]; other site
696406011212	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
696406011213	shikimate 5-dehydrogenase; Region: aroE; TIGR00507
696406011214	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
696406011215	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
696406011216	shikimate binding site; other site
696406011217	NAD(P) binding site [chemical binding]; other site
696406011218	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
696406011219	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
696406011220	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
696406011221	hypothetical protein; Validated; Region: PRK03430
696406011222	hypothetical protein; Provisional; Region: PRK10736
696406011223	DNA protecting protein DprA; Region: dprA; TIGR00732
696406011224	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
696406011225	active site
696406011226	catalytic residues [active]
696406011227	metal binding site [ion binding]; metal-binding site
696406011228	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
696406011229	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
696406011230	putative active site [active]
696406011231	substrate binding site [chemical binding]; other site
696406011232	putative cosubstrate binding site; other site
696406011233	catalytic site [active]
696406011234	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
696406011235	substrate binding site [chemical binding]; other site
696406011236	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
696406011237	putative RNA binding site [nucleotide binding]; other site
696406011238	16S rRNA methyltransferase B; Provisional; Region: PRK10901
696406011239	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406011240	S-adenosylmethionine binding site [chemical binding]; other site
696406011241	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
696406011242	TrkA-N domain; Region: TrkA_N; pfam02254
696406011243	TrkA-C domain; Region: TrkA_C; pfam02080
696406011244	TrkA-N domain; Region: TrkA_N; pfam02254
696406011245	TrkA-C domain; Region: TrkA_C; pfam02080
696406011246	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
696406011247	Large-conductance mechanosensitive channel, MscL; Region: MscL; pfam01741
696406011248	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
696406011249	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
696406011250	DNA binding residues [nucleotide binding]
696406011251	dimer interface [polypeptide binding]; other site
696406011252	metal binding site [ion binding]; metal-binding site
696406011253	hypothetical protein; Provisional; Region: PRK10203
696406011254	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
696406011255	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
696406011256	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
696406011257	alphaNTD homodimer interface [polypeptide binding]; other site
696406011258	alphaNTD - beta interaction site [polypeptide binding]; other site
696406011259	alphaNTD - beta' interaction site [polypeptide binding]; other site
696406011260	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
696406011261	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
696406011262	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
696406011263	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
696406011264	RNA binding surface [nucleotide binding]; other site
696406011265	30S ribosomal protein S11; Validated; Region: PRK05309
696406011266	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
696406011267	30S ribosomal protein S13; Region: bact_S13; TIGR03631
696406011268	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
696406011269	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
696406011270	SecY translocase; Region: SecY; pfam00344
696406011271	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
696406011272	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
696406011273	23S rRNA binding site [nucleotide binding]; other site
696406011274	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
696406011275	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
696406011276	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
696406011277	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
696406011278	23S rRNA interface [nucleotide binding]; other site
696406011279	5S rRNA interface [nucleotide binding]; other site
696406011280	L27 interface [polypeptide binding]; other site
696406011281	L5 interface [polypeptide binding]; other site
696406011282	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
696406011283	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
696406011284	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
696406011285	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
696406011286	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
696406011287	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
696406011288	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
696406011289	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
696406011290	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
696406011291	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
696406011292	RNA binding site [nucleotide binding]; other site
696406011293	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
696406011294	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
696406011295	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
696406011296	23S rRNA interface [nucleotide binding]; other site
696406011297	putative translocon interaction site; other site
696406011298	signal recognition particle (SRP54) interaction site; other site
696406011299	L23 interface [polypeptide binding]; other site
696406011300	trigger factor interaction site; other site
696406011301	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
696406011302	23S rRNA interface [nucleotide binding]; other site
696406011303	5S rRNA interface [nucleotide binding]; other site
696406011304	putative antibiotic binding site [chemical binding]; other site
696406011305	L25 interface [polypeptide binding]; other site
696406011306	L27 interface [polypeptide binding]; other site
696406011307	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
696406011308	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
696406011309	G-X-X-G motif; other site
696406011310	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
696406011311	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
696406011312	protein-rRNA interface [nucleotide binding]; other site
696406011313	putative translocon binding site; other site
696406011314	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
696406011315	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
696406011316	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
696406011317	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
696406011318	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
696406011319	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
696406011320	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
696406011321	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
696406011322	protein secretion protein GspB; Provisional; Region: PRK09697
696406011323	Type II secretory pathway, component PulC [Intracellular trafficking and secretion]; Region: PulC; COG3031
696406011324	Type IV pilus biogenesis; Region: Pilus_PilP; pfam11356
696406011325	type II secretion system protein D; Region: type_II_gspD; TIGR02517
696406011326	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
696406011327	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
696406011328	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
696406011329	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
696406011330	Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulE; COG2804
696406011331	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
696406011332	Walker A motif; other site
696406011333	ATP binding site [chemical binding]; other site
696406011334	Walker B motif; other site
696406011335	type II secretion system protein F; Region: GspF; TIGR02120
696406011336	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
696406011337	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
696406011338	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
696406011339	type II secretion system protein G; Region: typeII_sec_gspG; TIGR01710
696406011340	Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334
696406011341	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
696406011342	type II secretion system protein I; Region: gspI; TIGR01707
696406011343	Type II secretion system (T2SS), protein I; Region: T2SI; pfam02501
696406011344	Type II secretory pathway, component PulJ [Intracellular trafficking and secretion]; Region: PulJ; COG4795
696406011345	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
696406011346	Type II secretion system (T2SS), protein J; Region: T2SJ; pfam11612
696406011347	Type II secretory pathway, component PulK [Intracellular trafficking and secretion]; Region: PulK; COG3156
696406011348	Type II secretory pathway, component PulL [Intracellular trafficking and secretion]; Region: PulL; COG3297
696406011349	Type II secretion system (T2SS), protein L; Region: T2SL; pfam05134
696406011350	GspL periplasmic domain; Region: GspL_C; pfam12693
696406011351	Type II secretion system (T2SS), protein M; Region: T2SM; pfam04612
696406011352	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
696406011353	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
696406011354	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
696406011355	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
696406011356	heme binding site [chemical binding]; other site
696406011357	ferroxidase pore; other site
696406011358	ferroxidase diiron center [ion binding]; other site
696406011359	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
696406011360	Chitin/cellulose binding domains of chitinase and related enzymes; Region: ChtBD3; cl00046
696406011361	Chitin/cellulose binding domains of chitinase and related enzymes; Region: ChtBD3; cl00046
696406011362	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
696406011363	aromatic chitin/cellulose binding site residues [chemical binding]; other site
696406011364	PF-ChiA is an uncharacterized chitinase found in the hyperthermophilic archaeon Pyrococcus furiosus with a glycosyl hydrolase family 18 (GH18) catalytic domain as well as a cellulose-binding domain.  Members of this domain family are found not only in...; Region: GH18_PF-ChiA-like; cd06543
696406011365	active site
696406011366	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
696406011367	Switch II region; other site
696406011368	G4 box; other site
696406011369	G5 box; other site
696406011370	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
696406011371	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
696406011372	Antibiotic Binding Site [chemical binding]; other site
696406011373	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
696406011374	G1 box; other site
696406011375	GTP/Mg2+ binding site [chemical binding]; other site
696406011376	G2 box; other site
696406011377	Switch I region; other site
696406011378	elongation factor G; Reviewed; Region: PRK00007
696406011379	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
696406011380	G1 box; other site
696406011381	putative GEF interaction site [polypeptide binding]; other site
696406011382	GTP/Mg2+ binding site [chemical binding]; other site
696406011383	Switch I region; other site
696406011384	G2 box; other site
696406011385	G3 box; other site
696406011386	Switch II region; other site
696406011387	G4 box; other site
696406011388	G5 box; other site
696406011389	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
696406011390	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
696406011391	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
696406011392	30S ribosomal protein S7; Validated; Region: PRK05302
696406011393	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
696406011394	S17 interaction site [polypeptide binding]; other site
696406011395	S8 interaction site; other site
696406011396	16S rRNA interaction site [nucleotide binding]; other site
696406011397	streptomycin interaction site [chemical binding]; other site
696406011398	23S rRNA interaction site [nucleotide binding]; other site
696406011399	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
696406011400	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
696406011401	sulfur relay protein TusC; Validated; Region: PRK00211
696406011402	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
696406011403	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
696406011404	YheO-like PAS domain; Region: PAS_6; pfam08348
696406011405	HTH domain; Region: HTH_22; pfam13309
696406011406	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
696406011407	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
696406011408	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
696406011409	phi X174 lysis protein; Provisional; Region: PRK02793
696406011410	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
696406011411	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
696406011412	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
696406011413	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
696406011414	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
696406011415	TrkA-N domain; Region: TrkA_N; pfam02254
696406011416	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
696406011417	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
696406011418	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
696406011419	Walker A/P-loop; other site
696406011420	ATP binding site [chemical binding]; other site
696406011421	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
696406011422	ABC transporter signature motif; other site
696406011423	Walker B; other site
696406011424	D-loop; other site
696406011425	ABC transporter; Region: ABC_tran_2; pfam12848
696406011426	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
696406011427	putative hydrolase; Provisional; Region: PRK10985
696406011428	hypothetical protein; Provisional; Region: PRK04966
696406011429	Phosphoribulokinase-like (PRK-like) is a family of proteins similar to phosphoribulokinase (PRK), the enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. PRK catalyzes the phosphorylation of D-ribulose 5-phosphate to...; Region: PRK_like; cd02029
696406011430	active site
696406011431	hypothetical protein; Provisional; Region: PRK10738
696406011432	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
696406011433	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
696406011434	ligand binding site [chemical binding]; other site
696406011435	flexible hinge region; other site
696406011436	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
696406011437	putative switch regulator; other site
696406011438	non-specific DNA interactions [nucleotide binding]; other site
696406011439	DNA binding site [nucleotide binding]
696406011440	sequence specific DNA binding site [nucleotide binding]; other site
696406011441	putative cAMP binding site [chemical binding]; other site
696406011442	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
696406011443	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
696406011444	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
696406011445	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
696406011446	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
696406011447	inhibitor-cofactor binding pocket; inhibition site
696406011448	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406011449	catalytic residue [active]
696406011450	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
696406011451	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
696406011452	glutamine binding [chemical binding]; other site
696406011453	catalytic triad [active]
696406011454	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
696406011455	cell filamentation protein Fic; Provisional; Region: PRK10347
696406011456	hypothetical protein; Provisional; Region: PRK10204
696406011457	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
696406011458	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
696406011459	substrate binding site [chemical binding]; other site
696406011460	putative transporter; Provisional; Region: PRK03699
696406011461	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406011462	putative substrate translocation pore; other site
696406011463	nitrite reductase subunit NirD; Provisional; Region: PRK14989
696406011464	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
696406011465	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
696406011466	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
696406011467	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
696406011468	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
696406011469	nitrite transporter NirC; Provisional; Region: PRK11562
696406011470	siroheme synthase; Provisional; Region: cysG; PRK10637
696406011471	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
696406011472	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
696406011473	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
696406011474	active site
696406011475	SAM binding site [chemical binding]; other site
696406011476	homodimer interface [polypeptide binding]; other site
696406011477	Protein of unknown function (DUF4223); Region: DUF4223; pfam13978
696406011478	putative fructoselysine transporter; Provisional; Region: frlA; PRK11357
696406011479	hypothetical protein; Provisional; Region: PHA02764
696406011480	fructoselysine-6-P-deglycase; Provisional; Region: frlB; PRK11382
696406011481	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
696406011482	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
696406011483	dimer interface [polypeptide binding]; other site
696406011484	active site
696406011485	fructoselysine 3-epimerase; Provisional; Region: PRK09856
696406011486	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
696406011487	AP (apurinic/apyrimidinic) site pocket; other site
696406011488	DNA interaction; other site
696406011489	Metal-binding active site; metal-binding site
696406011490	Fructoselysine kinase-like.  Fructoselysine is a fructoseamine formed by glycation, a non-enzymatic reaction of glucose with a primary amine followed by an Amadori rearrangement, resulting in a protein that is modified at the amino terminus and at the...; Region: Fructoselysine_kinase_like; cd01940
696406011491	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
696406011492	substrate binding site [chemical binding]; other site
696406011493	ATP binding site [chemical binding]; other site
696406011494	DNA-binding transcriptional regulator FrlR; Provisional; Region: PRK11402
696406011495	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
696406011496	DNA-binding site [nucleotide binding]; DNA binding site
696406011497	UTRA domain; Region: UTRA; pfam07702
696406011498	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
696406011499	DNA topoisomerase III, bacteria and conjugative plasmid; Region: topB; TIGR01056
696406011500	Protein of unknown function; Region: YhfT; pfam10797
696406011501	Protein of unknown function DUF2620; Region: DUF2620; pfam10941
696406011502	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
696406011503	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
696406011504	active site
696406011505	substrate binding pocket [chemical binding]; other site
696406011506	homodimer interaction site [polypeptide binding]; other site
696406011507	putative mutase; Provisional; Region: PRK12383
696406011508	Phosphopentomutase [Carbohydrate transport and metabolism]; Region: DeoB; COG1015
696406011509	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme yhfX; Region: PLPDE_III_yhfX_like; cd06811
696406011510	dimer interface [polypeptide binding]; other site
696406011511	Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457
696406011512	active site
696406011513	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
696406011514	substrate binding site [chemical binding]; other site
696406011515	catalytic residue [active]
696406011516	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
696406011517	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
696406011518	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
696406011519	active site
696406011520	HIGH motif; other site
696406011521	dimer interface [polypeptide binding]; other site
696406011522	KMSKS motif; other site
696406011523	phosphoglycolate phosphatase; Provisional; Region: PRK13222
696406011524	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696406011525	motif II; other site
696406011526	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
696406011527	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
696406011528	substrate binding site [chemical binding]; other site
696406011529	hexamer interface [polypeptide binding]; other site
696406011530	metal binding site [ion binding]; metal-binding site
696406011531	DNA adenine methylase; Provisional; Region: PRK10904
696406011532	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DamX; COG3266
696406011533	cell division protein DamX; Validated; Region: PRK10905
696406011534	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
696406011535	active site
696406011536	dimer interface [polypeptide binding]; other site
696406011537	metal binding site [ion binding]; metal-binding site
696406011538	shikimate kinase; Reviewed; Region: aroK; PRK00131
696406011539	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
696406011540	ADP binding site [chemical binding]; other site
696406011541	magnesium binding site [ion binding]; other site
696406011542	putative shikimate binding site; other site
696406011543	outer membrane porin HofQ; Provisional; Region: hofQ; PRK10560
696406011544	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
696406011545	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
696406011546	Protein of unknown function (DUF2531); Region: DUF2531; pfam10748
696406011547	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
696406011548	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
696406011549	Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972
696406011550	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
696406011551	Transglycosylase; Region: Transgly; pfam00912
696406011552	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
696406011553	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
696406011554	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
696406011555	ADP-ribose binding site [chemical binding]; other site
696406011556	dimer interface [polypeptide binding]; other site
696406011557	active site
696406011558	nudix motif; other site
696406011559	metal binding site [ion binding]; metal-binding site
696406011560	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
696406011561	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
696406011562	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696406011563	motif II; other site
696406011564	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
696406011565	RNA binding surface [nucleotide binding]; other site
696406011566	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
696406011567	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
696406011568	dimerization interface [polypeptide binding]; other site
696406011569	domain crossover interface; other site
696406011570	redox-dependent activation switch; other site
696406011571	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
696406011572	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
696406011573	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
696406011574	active site
696406011575	substrate-binding site [chemical binding]; other site
696406011576	metal-binding site [ion binding]
696406011577	ATP binding site [chemical binding]; other site
696406011578	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
696406011579	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
696406011580	dimerization interface [polypeptide binding]; other site
696406011581	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
696406011582	dimer interface [polypeptide binding]; other site
696406011583	phosphorylation site [posttranslational modification]
696406011584	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406011585	ATP binding site [chemical binding]; other site
696406011586	G-X-G motif; other site
696406011587	osmolarity response regulator; Provisional; Region: ompR; PRK09468
696406011588	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406011589	active site
696406011590	phosphorylation site [posttranslational modification]
696406011591	intermolecular recognition site; other site
696406011592	dimerization interface [polypeptide binding]; other site
696406011593	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
696406011594	DNA binding site [nucleotide binding]
696406011595	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
696406011596	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
696406011597	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
696406011598	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
696406011599	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
696406011600	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
696406011601	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
696406011602	RNA binding site [nucleotide binding]; other site
696406011603	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
696406011604	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
696406011605	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
696406011606	G1 box; other site
696406011607	GTP/Mg2+ binding site [chemical binding]; other site
696406011608	Switch I region; other site
696406011609	G2 box; other site
696406011610	G3 box; other site
696406011611	Switch II region; other site
696406011612	G4 box; other site
696406011613	G5 box; other site
696406011614	Nucleoside recognition; Region: Gate; pfam07670
696406011615	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
696406011616	Nucleoside recognition; Region: Gate; pfam07670
696406011617	ferrous iron transport protein FeoC; Provisional; Region: PRK15431
696406011618	putative transposase; Provisional; Region: PRK09857
696406011619	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
696406011620	pimelyl-[acyl-carrier protein] methyl ester esterase; Region: bioH; TIGR01738
696406011621	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
696406011622	DNA utilization protein GntX; Provisional; Region: PRK11595
696406011623	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
696406011624	active site
696406011625	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
696406011626	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
696406011627	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
696406011628	high-affinity gluconate transporter; Provisional; Region: PRK14984
696406011629	gluconate transporter; Region: gntP; TIGR00791
696406011630	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
696406011631	4-alpha-glucanotransferase; Region: malQ; TIGR00217
696406011632	maltodextrin phosphorylase; Provisional; Region: PRK14985
696406011633	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
696406011634	homodimer interface [polypeptide binding]; other site
696406011635	active site pocket [active]
696406011636	transcriptional regulator MalT; Provisional; Region: PRK04841
696406011637	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
696406011638	DNA binding residues [nucleotide binding]
696406011639	dimerization interface [polypeptide binding]; other site
696406011640	RNA 3'-terminal-phosphate cyclase; Provisional; Region: PRK04204
696406011641	RNA 3' phosphate cyclase domain -  RNA phosphate cyclases are enzymes that catalyze the ATP-dependent conversion of 3'-phosphate at the end of RNA into 2', 3'-cyclic phosphodiester bond. The enzymes are conserved in eucaryotes; Region: RNA_Cyclase; cd00295
696406011642	putative active site [active]
696406011643	adenylation catalytic residue [active]
696406011644	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
696406011645	hypothetical protein; Reviewed; Region: PRK09588
696406011646	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: RtcR; COG4650
696406011647	Regulator of RNA terminal phosphate cyclase; Region: RtcR; pfam06956
696406011648	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406011649	Walker A motif; other site
696406011650	ATP binding site [chemical binding]; other site
696406011651	Walker B motif; other site
696406011652	arginine finger; other site
696406011653	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
696406011654	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
696406011655	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
696406011656	intramembrane serine protease GlpG; Provisional; Region: PRK10907
696406011657	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
696406011658	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
696406011659	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
696406011660	active site residue [active]
696406011661	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
696406011662	hypothetical protein; Provisional; Region: PRK09781; cl08057
696406011663	ABC-type phosphate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PstS; COG0226
696406011664	glycogen phosphorylase; Provisional; Region: PRK14986
696406011665	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
696406011666	homodimer interface [polypeptide binding]; other site
696406011667	active site pocket [active]
696406011668	glycogen synthase; Provisional; Region: glgA; PRK00654
696406011669	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
696406011670	ADP-binding pocket [chemical binding]; other site
696406011671	homodimer interface [polypeptide binding]; other site
696406011672	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
696406011673	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
696406011674	ligand binding site; other site
696406011675	oligomer interface; other site
696406011676	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
696406011677	sulfate 1 binding site; other site
696406011678	glycogen debranching enzyme; Provisional; Region: PRK03705
696406011679	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
696406011680	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
696406011681	active site
696406011682	catalytic site [active]
696406011683	glycogen branching enzyme; Provisional; Region: PRK05402
696406011684	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
696406011685	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
696406011686	active site
696406011687	catalytic site [active]
696406011688	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
696406011689	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
696406011690	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
696406011691	putative antibiotic transporter; Provisional; Region: PRK10739
696406011692	low affinity gluconate transporter; Provisional; Region: PRK10472
696406011693	gluconate transporter; Region: gntP; TIGR00791
696406011694	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
696406011695	Shikimate kinase; Region: SKI; pfam01202
696406011696	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
696406011697	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
696406011698	DNA binding site [nucleotide binding]
696406011699	domain linker motif; other site
696406011700	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
696406011701	putative ligand binding site [chemical binding]; other site
696406011702	putative dimerization interface [polypeptide binding]; other site
696406011703	Pirin-related protein [General function prediction only]; Region: COG1741
696406011704	Pirin; Region: Pirin; pfam02678
696406011705	putative oxidoreductase; Provisional; Region: PRK10206
696406011706	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
696406011707	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
696406011708	putative acetyltransferase YhhY; Provisional; Region: PRK10140
696406011709	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
696406011710	Coenzyme A binding pocket [chemical binding]; other site
696406011711	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
696406011712	gamma-glutamyltranspeptidase; Reviewed; Region: ggt; PRK09615
696406011713	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
696406011714	hypothetical protein; Provisional; Region: PRK10350
696406011715	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
696406011716	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
696406011717	putative active site [active]
696406011718	catalytic site [active]
696406011719	putative metal binding site [ion binding]; other site
696406011720	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
696406011721	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
696406011722	Walker A/P-loop; other site
696406011723	ATP binding site [chemical binding]; other site
696406011724	Q-loop/lid; other site
696406011725	ABC transporter signature motif; other site
696406011726	Walker B; other site
696406011727	D-loop; other site
696406011728	H-loop/switch region; other site
696406011729	TOBE domain; Region: TOBE_2; pfam08402
696406011730	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
696406011731	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406011732	dimer interface [polypeptide binding]; other site
696406011733	conserved gate region; other site
696406011734	putative PBP binding loops; other site
696406011735	ABC-ATPase subunit interface; other site
696406011736	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
696406011737	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406011738	dimer interface [polypeptide binding]; other site
696406011739	conserved gate region; other site
696406011740	putative PBP binding loops; other site
696406011741	ABC-ATPase subunit interface; other site
696406011742	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
696406011743	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
696406011744	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
696406011745	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
696406011746	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
696406011747	Walker A/P-loop; other site
696406011748	ATP binding site [chemical binding]; other site
696406011749	Q-loop/lid; other site
696406011750	ABC transporter signature motif; other site
696406011751	Walker B; other site
696406011752	D-loop; other site
696406011753	H-loop/switch region; other site
696406011754	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
696406011755	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
696406011756	Walker A/P-loop; other site
696406011757	ATP binding site [chemical binding]; other site
696406011758	Q-loop/lid; other site
696406011759	ABC transporter signature motif; other site
696406011760	Walker B; other site
696406011761	D-loop; other site
696406011762	H-loop/switch region; other site
696406011763	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
696406011764	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
696406011765	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
696406011766	TM-ABC transporter signature motif; other site
696406011767	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
696406011768	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
696406011769	TM-ABC transporter signature motif; other site
696406011770	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
696406011771	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
696406011772	dimerization interface [polypeptide binding]; other site
696406011773	ligand binding site [chemical binding]; other site
696406011774	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
696406011775	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
696406011776	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
696406011777	dimerization interface [polypeptide binding]; other site
696406011778	ligand binding site [chemical binding]; other site
696406011779	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
696406011780	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
696406011781	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
696406011782	DNA binding residues [nucleotide binding]
696406011783	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
696406011784	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
696406011785	cell division protein FtsE; Provisional; Region: PRK10908
696406011786	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
696406011787	Walker A/P-loop; other site
696406011788	ATP binding site [chemical binding]; other site
696406011789	Q-loop/lid; other site
696406011790	ABC transporter signature motif; other site
696406011791	Walker B; other site
696406011792	D-loop; other site
696406011793	H-loop/switch region; other site
696406011794	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
696406011795	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
696406011796	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
696406011797	P loop; other site
696406011798	GTP binding site [chemical binding]; other site
696406011799	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
696406011800	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406011801	S-adenosylmethionine binding site [chemical binding]; other site
696406011802	hypothetical protein; Provisional; Region: PRK10910
696406011803	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
696406011804	Predicted membrane protein [Function unknown]; Region: COG3714
696406011805	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
696406011806	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
696406011807	metal-binding site [ion binding]
696406011808	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
696406011809	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
696406011810	CPxP  motif; other site
696406011811	hypothetical protein; Provisional; Region: PRK11212
696406011812	hypothetical protein; Provisional; Region: PRK11615
696406011813	major facilitator superfamily transporter; Provisional; Region: PRK05122
696406011814	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406011815	putative substrate translocation pore; other site
696406011816	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
696406011817	Domain of unknown function DUF20; Region: UPF0118; pfam01594
696406011818	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
696406011819	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
696406011820	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
696406011821	The substrate-binding component of an ABC-type nickel import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA; cd08489
696406011822	substrate binding site [chemical binding]; other site
696406011823	nickel transporter permease NikB; Provisional; Region: PRK10352
696406011824	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406011825	dimer interface [polypeptide binding]; other site
696406011826	conserved gate region; other site
696406011827	putative PBP binding loops; other site
696406011828	ABC-ATPase subunit interface; other site
696406011829	nickel transporter permease NikC; Provisional; Region: nikC; PRK10417
696406011830	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406011831	dimer interface [polypeptide binding]; other site
696406011832	conserved gate region; other site
696406011833	putative PBP binding loops; other site
696406011834	ABC-ATPase subunit interface; other site
696406011835	nickel transporter ATP-binding protein NikD; Provisional; Region: nikD; PRK10418
696406011836	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
696406011837	Walker A/P-loop; other site
696406011838	ATP binding site [chemical binding]; other site
696406011839	Q-loop/lid; other site
696406011840	ABC transporter signature motif; other site
696406011841	Walker B; other site
696406011842	D-loop; other site
696406011843	H-loop/switch region; other site
696406011844	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
696406011845	nickel transporter ATP-binding protein NikE; Provisional; Region: nikE; PRK10419
696406011846	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
696406011847	Walker A/P-loop; other site
696406011848	ATP binding site [chemical binding]; other site
696406011849	Q-loop/lid; other site
696406011850	ABC transporter signature motif; other site
696406011851	Walker B; other site
696406011852	D-loop; other site
696406011853	H-loop/switch region; other site
696406011854	nickel responsive regulator; Provisional; Region: PRK02967
696406011855	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
696406011856	PAAR motif; Region: PAAR_motif; cl15808
696406011857	RHS Repeat; Region: RHS_repeat; pfam05593
696406011858	RHS Repeat; Region: RHS_repeat; pfam05593
696406011859	RHS Repeat; Region: RHS_repeat; cl11982
696406011860	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
696406011861	RHS Repeat; Region: RHS_repeat; pfam05593
696406011862	RHS Repeat; Region: RHS_repeat; pfam05593
696406011863	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
696406011864	RHS protein; Region: RHS; pfam03527
696406011865	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
696406011866	Domain of unknown function (DUF4329); Region: DUF4329; pfam14220
696406011867	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
696406011868	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
696406011869	Transposase [DNA replication, recombination, and repair]; Region: COG5433
696406011870	Transposase [DNA replication, recombination, and repair]; Region: COG5433
696406011871	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
696406011872	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
696406011873	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
696406011874	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
696406011875	Walker A/P-loop; other site
696406011876	ATP binding site [chemical binding]; other site
696406011877	Q-loop/lid; other site
696406011878	ABC transporter signature motif; other site
696406011879	Walker B; other site
696406011880	D-loop; other site
696406011881	H-loop/switch region; other site
696406011882	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
696406011883	Walker A/P-loop; other site
696406011884	ATP binding site [chemical binding]; other site
696406011885	Q-loop/lid; other site
696406011886	ABC transporter signature motif; other site
696406011887	Walker B; other site
696406011888	D-loop; other site
696406011889	H-loop/switch region; other site
696406011890	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
696406011891	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
696406011892	HlyD family secretion protein; Region: HlyD; pfam00529
696406011893	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
696406011894	HlyD family secretion protein; Region: HlyD_3; pfam13437
696406011895	Domain of unknown function (DUF4049); Region: DUF4049; pfam13258
696406011896	Domain of unknown function (DUF4049); Region: DUF4049; pfam13258
696406011897	Protein of unknown function (DUF2776); Region: DUF2776; pfam10951
696406011898	Predicted flavoproteins [General function prediction only]; Region: COG2081
696406011899	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
696406011900	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
696406011901	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
696406011902	universal stress protein UspB; Provisional; Region: PRK04960
696406011903	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
696406011904	Ligand Binding Site [chemical binding]; other site
696406011905	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
696406011906	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406011907	POT family; Region: PTR2; pfam00854
696406011908	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406011909	S-adenosylmethionine binding site [chemical binding]; other site
696406011910	oligopeptidase A; Provisional; Region: PRK10911
696406011911	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
696406011912	active site
696406011913	Zn binding site [ion binding]; other site
696406011914	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
696406011915	glutathione reductase; Validated; Region: PRK06116
696406011916	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
696406011917	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
696406011918	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
696406011919	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
696406011920	dimerization interface [polypeptide binding]; other site
696406011921	putative DNA binding site [nucleotide binding]; other site
696406011922	putative Zn2+ binding site [ion binding]; other site
696406011923	arsenical pump membrane protein; Provisional; Region: PRK15445
696406011924	Anion permease ArsB.  These permeases have been shown to export arsenate and antimonite in eubacteria and archaea.  A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118
696406011925	transmembrane helices; other site
696406011926	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
696406011927	ArsC family; Region: ArsC; pfam03960
696406011928	catalytic residues [active]
696406011929	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
696406011930	dimerization interface [polypeptide binding]; other site
696406011931	putative DNA binding site [nucleotide binding]; other site
696406011932	putative Zn2+ binding site [ion binding]; other site
696406011933	Predicted permeases [General function prediction only]; Region: COG0701
696406011934	outer membrane lipoprotein, Slp family; Region: slp; TIGR00752
696406011935	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
696406011936	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
696406011937	DNA binding residues [nucleotide binding]
696406011938	dimerization interface [polypeptide binding]; other site
696406011939	putative Mg(2+) transport ATPase; Provisional; Region: PRK09977
696406011940	MgtC family; Region: MgtC; pfam02308
696406011941	acid-resistance protein; Provisional; Region: hdeB; PRK11566
696406011942	acid-resistance protein; Provisional; Region: PRK10208
696406011943	acid-resistance membrane protein; Provisional; Region: PRK10209
696406011944	Uncharacterized conserved protein [Function unknown]; Region: HdeD; COG3247
696406011945	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
696406011946	pyruvate kinase; Provisional; Region: PRK05826
696406011947	multidrug efflux system protein MdtE; Provisional; Region: PRK09859
696406011948	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
696406011949	HlyD family secretion protein; Region: HlyD_3; pfam13437
696406011950	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
696406011951	Protein export membrane protein; Region: SecD_SecF; cl14618
696406011952	transcriptional regulator YdeO; Provisional; Region: PRK09940
696406011953	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406011954	DNA-binding transcriptional regulator GadX; Provisional; Region: PRK09978
696406011955	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406011956	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
696406011957	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406011958	catalytic residue [active]
696406011959	Haem-binding domain; Region: Haem_bd; pfam14376
696406011960	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
696406011961	trehalase; Provisional; Region: treF; PRK13270
696406011962	Trehalase; Region: Trehalase; pfam01204
696406011963	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
696406011964	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
696406011965	DNA binding residues [nucleotide binding]
696406011966	dimerization interface [polypeptide binding]; other site
696406011967	Transcriptional regulator [Transcription]; Region: LysR; COG0583
696406011968	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406011969	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
696406011970	putative effector binding pocket; other site
696406011971	putative dimerization interface [polypeptide binding]; other site
696406011972	inner membrane protein YhjD; Region: TIGR00766
696406011973	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406011974	metabolite-proton symporter; Region: 2A0106; TIGR00883
696406011975	putative substrate translocation pore; other site
696406011976	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
696406011977	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
696406011978	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
696406011979	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
696406011980	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
696406011981	substrate binding site [chemical binding]; other site
696406011982	ATP binding site [chemical binding]; other site
696406011983	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
696406011984	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
696406011985	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
696406011986	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
696406011987	putative diguanylate cyclase; Provisional; Region: PRK13561
696406011988	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
696406011989	metal binding site [ion binding]; metal-binding site
696406011990	active site
696406011991	I-site; other site
696406011992	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
696406011993	cellulose synthase subunit BcsC; Provisional; Region: PRK11447
696406011994	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
696406011995	binding surface
696406011996	TPR motif; other site
696406011997	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
696406011998	binding surface
696406011999	TPR motif; other site
696406012000	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
696406012001	endo-1,4-D-glucanase; Provisional; Region: PRK11097
696406012002	cellulose synthase regulator protein; Provisional; Region: PRK11114
696406012003	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
696406012004	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
696406012005	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
696406012006	DXD motif; other site
696406012007	PilZ domain; Region: PilZ; pfam07238
696406012008	cell division protein; Provisional; Region: PRK10037
696406012009	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
696406012010	cellulose biosynthesis protein BcsE; Provisional; Region: PRK15045
696406012011	Protein of unknown function (DUF2819); Region: DUF2819; pfam10995
696406012012	celllulose biosynthesis operon protein BcsF/YhjT; Region: cellullose_BcsF; TIGR03493
696406012013	Protein of unknown function (DUF3260); Region: DUF3260; pfam11658
696406012014	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
696406012015	serine transporter; Region: stp; TIGR00814
696406012016	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
696406012017	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
696406012018	Walker A/P-loop; other site
696406012019	ATP binding site [chemical binding]; other site
696406012020	Q-loop/lid; other site
696406012021	ABC transporter signature motif; other site
696406012022	Walker B; other site
696406012023	D-loop; other site
696406012024	H-loop/switch region; other site
696406012025	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
696406012026	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
696406012027	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
696406012028	Walker A/P-loop; other site
696406012029	ATP binding site [chemical binding]; other site
696406012030	Q-loop/lid; other site
696406012031	ABC transporter signature motif; other site
696406012032	Walker B; other site
696406012033	D-loop; other site
696406012034	H-loop/switch region; other site
696406012035	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
696406012036	dipeptide transporter; Provisional; Region: PRK10913
696406012037	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
696406012038	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406012039	dimer interface [polypeptide binding]; other site
696406012040	conserved gate region; other site
696406012041	putative PBP binding loops; other site
696406012042	ABC-ATPase subunit interface; other site
696406012043	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
696406012044	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406012045	dimer interface [polypeptide binding]; other site
696406012046	conserved gate region; other site
696406012047	putative PBP binding loops; other site
696406012048	ABC-ATPase subunit interface; other site
696406012049	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
696406012050	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
696406012051	peptide binding site [polypeptide binding]; other site
696406012052	phosphoethanolamine transferase; Provisional; Region: PRK11560
696406012053	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
696406012054	Sulfatase; Region: Sulfatase; pfam00884
696406012055	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
696406012056	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406012057	putative substrate translocation pore; other site
696406012058	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
696406012059	3-methyl-adenine DNA glycosylase I; Provisional; Region: PRK10353
696406012060	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
696406012061	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
696406012062	Coenzyme A binding pocket [chemical binding]; other site
696406012063	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
696406012064	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
696406012065	molybdopterin cofactor binding site [chemical binding]; other site
696406012066	substrate binding site [chemical binding]; other site
696406012067	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
696406012068	molybdopterin cofactor binding site; other site
696406012069	putative outer membrane lipoprotein; Provisional; Region: PRK10510
696406012070	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
696406012071	ligand binding site [chemical binding]; other site
696406012072	bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409
696406012073	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
696406012074	dimerization interface [polypeptide binding]; other site
696406012075	ligand binding site [chemical binding]; other site
696406012076	NADP binding site [chemical binding]; other site
696406012077	catalytic site [active]
696406012078	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
696406012079	Predicted transcriptional regulator [Transcription]; Region: COG2944
696406012080	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
696406012081	non-specific DNA binding site [nucleotide binding]; other site
696406012082	salt bridge; other site
696406012083	sequence-specific DNA binding site [nucleotide binding]; other site
696406012084	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
696406012085	DNA-binding site [nucleotide binding]; DNA binding site
696406012086	RNA-binding motif; other site
696406012087	small toxic polypeptide; Provisional; Region: PRK09759
696406012088	putative transposase OrfB; Reviewed; Region: PHA02517
696406012089	HTH-like domain; Region: HTH_21; pfam13276
696406012090	Integrase core domain; Region: rve; pfam00665
696406012091	Integrase core domain; Region: rve_2; pfam13333
696406012092	glycyl-tRNA synthetase, tetrameric type, beta subunit; Region: glyS; TIGR00211
696406012093	DALR anticodon binding domain; Region: DALR_1; pfam05746
696406012094	anticodon binding site; other site
696406012095	tRNA binding surface [nucleotide binding]; other site
696406012096	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
696406012097	dimer interface [polypeptide binding]; other site
696406012098	motif 1; other site
696406012099	active site
696406012100	motif 2; other site
696406012101	motif 3; other site
696406012102	YsaB-like lipoprotein; Region: YsaB; pfam13983
696406012103	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
696406012104	Acyltransferase family; Region: Acyl_transf_3; pfam01757
696406012105	hypothetical protein; Provisional; Region: PRK11383
696406012106	yiaA/B two helix domain; Region: YiaAB; pfam05360
696406012107	yiaA/B two helix domain; Region: YiaAB; pfam05360
696406012108	hypothetical protein; Provisional; Region: PRK11403
696406012109	yiaA/B two helix domain; Region: YiaAB; pfam05360
696406012110	xylulokinase; Provisional; Region: PRK15027
696406012111	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
696406012112	N- and C-terminal domain interface [polypeptide binding]; other site
696406012113	active site
696406012114	MgATP binding site [chemical binding]; other site
696406012115	catalytic site [active]
696406012116	metal binding site [ion binding]; metal-binding site
696406012117	xylulose binding site [chemical binding]; other site
696406012118	homodimer interface [polypeptide binding]; other site
696406012119	xylose isomerase; Provisional; Region: PRK05474
696406012120	xylose isomerase; Region: xylose_isom_A; TIGR02630
696406012121	D-xylose transporter subunit XylF; Provisional; Region: xylF; PRK10355
696406012122	Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_xylose_binding; cd01538
696406012123	putative ligand binding site [chemical binding]; other site
696406012124	xylose transporter ATP-binding subunit; Provisional; Region: PRK13549
696406012125	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
696406012126	Walker A/P-loop; other site
696406012127	ATP binding site [chemical binding]; other site
696406012128	Q-loop/lid; other site
696406012129	ABC transporter signature motif; other site
696406012130	Walker B; other site
696406012131	D-loop; other site
696406012132	H-loop/switch region; other site
696406012133	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
696406012134	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
696406012135	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
696406012136	TM-ABC transporter signature motif; other site
696406012137	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
696406012138	putative dimerization interface [polypeptide binding]; other site
696406012139	Transcriptional regulators [Transcription]; Region: PurR; COG1609
696406012140	putative ligand binding site [chemical binding]; other site
696406012141	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406012142	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
696406012143	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406012144	Uncharacterized FlgJ-related protein [General function prediction only]; Region: Bax; COG2992
696406012145	hypothetical protein; Provisional; Region: PRK10356
696406012146	alpha-amylase; Reviewed; Region: malS; PRK09505
696406012147	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
696406012148	active site
696406012149	catalytic site [active]
696406012150	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
696406012151	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
696406012152	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406012153	homodimer interface [polypeptide binding]; other site
696406012154	catalytic residue [active]
696406012155	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
696406012156	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
696406012157	Transcriptional regulator [Transcription]; Region: IclR; COG1414
696406012158	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
696406012159	Bacterial transcriptional regulator; Region: IclR; pfam01614
696406012160	2,3-diketo-L-gulonate reductase; Provisional; Region: PRK13260
696406012161	uncharacterized protein, YhcH/YjgK/YiaL family; Region: TIGR00022
696406012162	2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM; Provisional; Region: PRK09877
696406012163	L-dehydroascorbate transporter large permease subunit; Provisional; Region: PRK15060
696406012164	DctM-like transporters; Region: DctM; pfam06808
696406012165	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
696406012166	tripartite ATP-independent periplasmic transporter solute receptor, DctP family; Region: dctP; TIGR00787
696406012167	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
696406012168	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
696406012169	putative N- and C-terminal domain interface [polypeptide binding]; other site
696406012170	putative active site [active]
696406012171	MgATP binding site [chemical binding]; other site
696406012172	catalytic site [active]
696406012173	metal binding site [ion binding]; metal-binding site
696406012174	putative xylulose binding site [chemical binding]; other site
696406012175	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
696406012176	active site
696406012177	dimer interface [polypeptide binding]; other site
696406012178	magnesium binding site [ion binding]; other site
696406012179	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
696406012180	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
696406012181	AP (apurinic/apyrimidinic) site pocket; other site
696406012182	DNA interaction; other site
696406012183	Metal-binding active site; metal-binding site
696406012184	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
696406012185	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
696406012186	intersubunit interface [polypeptide binding]; other site
696406012187	active site
696406012188	Zn2+ binding site [ion binding]; other site
696406012189	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
696406012190	Transcriptional regulator [Transcription]; Region: LysR; COG0583
696406012191	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406012192	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
696406012193	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
696406012194	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
696406012195	HlyD family secretion protein; Region: HlyD_3; pfam13437
696406012196	Protein of unknown function (DUF3302); Region: DUF3302; pfam11742
696406012197	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like; Region: ALDH_ACDHII-AcoD; cd07116
696406012198	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
696406012199	NAD(P) binding site [chemical binding]; other site
696406012200	catalytic residues [active]
696406012201	putative alcohol dehydrogenase; Provisional; Region: PRK09860
696406012202	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
696406012203	dimer interface [polypeptide binding]; other site
696406012204	active site
696406012205	metal binding site [ion binding]; metal-binding site
696406012206	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
696406012207	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
696406012208	G1 box; other site
696406012209	putative GEF interaction site [polypeptide binding]; other site
696406012210	GTP/Mg2+ binding site [chemical binding]; other site
696406012211	Switch I region; other site
696406012212	G2 box; other site
696406012213	G3 box; other site
696406012214	Switch II region; other site
696406012215	G4 box; other site
696406012216	G5 box; other site
696406012217	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
696406012218	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
696406012219	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
696406012220	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
696406012221	selenocysteine synthase; Provisional; Region: PRK04311
696406012222	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
696406012223	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
696406012224	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
696406012225	catalytic residue [active]
696406012226	putative glutathione S-transferase; Provisional; Region: PRK10357
696406012227	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
696406012228	putative C-terminal domain interface [polypeptide binding]; other site
696406012229	putative GSH binding site (G-site) [chemical binding]; other site
696406012230	putative dimer interface [polypeptide binding]; other site
696406012231	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
696406012232	dimer interface [polypeptide binding]; other site
696406012233	N-terminal domain interface [polypeptide binding]; other site
696406012234	putative substrate binding pocket (H-site) [chemical binding]; other site
696406012235	PAAR motif; Region: PAAR_motif; cl15808
696406012236	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
696406012237	RHS Repeat; Region: RHS_repeat; pfam05593
696406012238	RHS Repeat; Region: RHS_repeat; cl11982
696406012239	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
696406012240	RHS Repeat; Region: RHS_repeat; pfam05593
696406012241	RHS Repeat; Region: RHS_repeat; pfam05593
696406012242	RHS protein; Region: RHS; pfam03527
696406012243	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
696406012244	putative lyase; Provisional; Region: PRK09687
696406012245	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
696406012246	RHS protein; Region: RHS; pfam03527
696406012247	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
696406012248	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
696406012249	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
696406012250	HlyD family secretion protein; Region: HlyD_3; pfam13437
696406012251	Protein of unknown function (DUF3302); Region: DUF3302; pfam11742
696406012252	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
696406012253	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
696406012254	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
696406012255	active site
696406012256	P-loop; other site
696406012257	phosphorylation site [posttranslational modification]
696406012258	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
696406012259	active site
696406012260	phosphorylation site [posttranslational modification]
696406012261	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
696406012262	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
696406012263	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
696406012264	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
696406012265	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
696406012266	hypothetical protein; Provisional; Region: PRK11020
696406012267	L-lactate permease; Provisional; Region: PRK10420
696406012268	glycolate transporter; Provisional; Region: PRK09695
696406012269	DNA-binding transcriptional repressor LldR; Provisional; Region: PRK10421
696406012270	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
696406012271	DNA-binding site [nucleotide binding]; DNA binding site
696406012272	FCD domain; Region: FCD; pfam07729
696406012273	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
696406012274	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
696406012275	phosphate binding site [ion binding]; other site
696406012276	putative rRNA methylase; Provisional; Region: PRK10358
696406012277	serine acetyltransferase; Provisional; Region: cysE; PRK11132
696406012278	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
696406012279	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
696406012280	trimer interface [polypeptide binding]; other site
696406012281	active site
696406012282	substrate binding site [chemical binding]; other site
696406012283	CoA binding site [chemical binding]; other site
696406012284	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
696406012285	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
696406012286	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
696406012287	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
696406012288	SecA binding site; other site
696406012289	Preprotein binding site; other site
696406012290	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
696406012291	GSH binding site [chemical binding]; other site
696406012292	catalytic residues [active]
696406012293	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
696406012294	active site residue [active]
696406012295	phosphoglyceromutase; Provisional; Region: PRK05434
696406012296	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
696406012297	AmiB activator; Provisional; Region: PRK11637
696406012298	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
696406012299	Peptidase family M23; Region: Peptidase_M23; pfam01551
696406012300	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
696406012301	NodB motif; other site
696406012302	putative active site [active]
696406012303	putative catalytic site [active]
696406012304	Zn binding site [ion binding]; other site
696406012305	putative glycosyl transferase; Provisional; Region: PRK10073
696406012306	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
696406012307	active site
696406012308	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
696406012309	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
696406012310	NAD(P) binding site [chemical binding]; other site
696406012311	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
696406012312	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
696406012313	substrate-cofactor binding pocket; other site
696406012314	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406012315	catalytic residue [active]
696406012316	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
696406012317	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
696406012318	NADP binding site [chemical binding]; other site
696406012319	homopentamer interface [polypeptide binding]; other site
696406012320	substrate binding site [chemical binding]; other site
696406012321	active site
696406012322	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
696406012323	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
696406012324	putative active site [active]
696406012325	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
696406012326	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
696406012327	putative active site [active]
696406012328	Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of...; Region: Glyco_transf_25; cd06532
696406012329	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
696406012330	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
696406012331	Ligand binding site; other site
696406012332	metal-binding site
696406012333	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
696406012334	Lipopolysaccharide core biosynthesis protein (WaaY); Region: WaaY; pfam06176
696406012335	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
696406012336	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
696406012337	Ligand binding site; other site
696406012338	metal-binding site
696406012339	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
696406012340	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
696406012341	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
696406012342	Ligand binding site; other site
696406012343	metal-binding site
696406012344	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
696406012345	lipopolysaccharide core heptose(I) kinase RfaP; Provisional; Region: PRK15123
696406012346	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
696406012347	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
696406012348	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
696406012349	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
696406012350	putative active site [active]
696406012351	3-deoxy-D-manno-octulosonic-acid transferase [Cell envelope biogenesis, outer membrane]; Region: KdtA; COG1519
696406012352	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
696406012353	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
696406012354	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
696406012355	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
696406012356	active site
696406012357	(T/H)XGH motif; other site
696406012358	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
696406012359	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
696406012360	DNA binding site [nucleotide binding]
696406012361	catalytic residue [active]
696406012362	H2TH interface [polypeptide binding]; other site
696406012363	putative catalytic residues [active]
696406012364	turnover-facilitating residue; other site
696406012365	intercalation triad [nucleotide binding]; other site
696406012366	8OG recognition residue [nucleotide binding]; other site
696406012367	putative reading head residues; other site
696406012368	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
696406012369	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
696406012370	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
696406012371	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
696406012372	hypothetical protein; Reviewed; Region: PRK00024
696406012373	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
696406012374	MPN+ (JAMM) motif; other site
696406012375	Zinc-binding site [ion binding]; other site
696406012376	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
696406012377	Flavoprotein; Region: Flavoprotein; pfam02441
696406012378	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
696406012379	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
696406012380	trimer interface [polypeptide binding]; other site
696406012381	active site
696406012382	division inhibitor protein; Provisional; Region: slmA; PRK09480
696406012383	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
696406012384	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
696406012385	active site
696406012386	ribonuclease PH; Reviewed; Region: rph; PRK00173
696406012387	Ribonuclease PH; Region: RNase_PH_bact; cd11362
696406012388	hexamer interface [polypeptide binding]; other site
696406012389	active site
696406012390	hypothetical protein; Provisional; Region: PRK11820
696406012391	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
696406012392	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
696406012393	integrase; Provisional; Region: PRK09692
696406012394	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
696406012395	active site
696406012396	Int/Topo IB signature motif; other site
696406012397	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523
696406012398	AntA/AntB antirepressor; Region: AntA; pfam08346
696406012399	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases; Region: PFK; cl00204
696406012400	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4643
696406012401	Zinc-binding domain of primase-helicase; Region: Prim_Zn_Ribbon; smart00778
696406012402	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
696406012403	active site
696406012404	metal binding site [ion binding]; metal-binding site
696406012405	interdomain interaction site; other site
696406012406	Superfamily II helicase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG5519
696406012407	PerC transcriptional activator; Region: PerC; pfam06069
696406012408	DNA-damage-inducible protein D; Provisional; Region: dinD; PRK11525
696406012409	BRO family, N-terminal domain; Region: Bro-N; pfam02498
696406012410	Predicted membrane protein [Function unknown]; Region: COG2860
696406012411	UPF0126 domain; Region: UPF0126; pfam03458
696406012412	UPF0126 domain; Region: UPF0126; pfam03458
696406012413	NAD-dependent DNA ligase LigB; Reviewed; Region: ligB; PRK08097
696406012414	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
696406012415	nucleotide binding pocket [chemical binding]; other site
696406012416	K-X-D-G motif; other site
696406012417	catalytic site [active]
696406012418	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
696406012419	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
696406012420	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
696406012421	catalytic site [active]
696406012422	G-X2-G-X-G-K; other site
696406012423	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
696406012424	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
696406012425	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
696406012426	Zn2+ binding site [ion binding]; other site
696406012427	Mg2+ binding site [ion binding]; other site
696406012428	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
696406012429	synthetase active site [active]
696406012430	NTP binding site [chemical binding]; other site
696406012431	metal binding site [ion binding]; metal-binding site
696406012432	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
696406012433	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
696406012434	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
696406012435	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
696406012436	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
696406012437	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
696406012438	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
696406012439	generic binding surface II; other site
696406012440	ssDNA binding site; other site
696406012441	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
696406012442	ATP binding site [chemical binding]; other site
696406012443	putative Mg++ binding site [ion binding]; other site
696406012444	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
696406012445	nucleotide binding region [chemical binding]; other site
696406012446	ATP-binding site [chemical binding]; other site
696406012447	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
696406012448	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
696406012449	AsmA family; Region: AsmA; pfam05170
696406012450	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
696406012451	putative alpha-glucosidase; Provisional; Region: PRK10658
696406012452	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
696406012453	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
696406012454	active site
696406012455	homotrimer interface [polypeptide binding]; other site
696406012456	catalytic site [active]
696406012457	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
696406012458	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
696406012459	sugar efflux transporter; Region: 2A0120; TIGR00899
696406012460	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406012461	putative substrate translocation pore; other site
696406012462	EamA-like transporter family; Region: EamA; pfam00892
696406012463	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
696406012464	EamA-like transporter family; Region: EamA; pfam00892
696406012465	cytoplasmic membrane lipoprotein-28; Provisional; Region: PRK09861
696406012466	lipoprotein, YaeC family; Region: TIGR00363
696406012467	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
696406012468	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
696406012469	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406012470	putative substrate translocation pore; other site
696406012471	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
696406012472	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
696406012473	cryptic adenine deaminase; Provisional; Region: PRK10027
696406012474	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
696406012475	Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295
696406012476	active site
696406012477	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
696406012478	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
696406012479	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406012480	putative substrate translocation pore; other site
696406012481	regulatory protein UhpC; Provisional; Region: PRK11663
696406012482	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406012483	putative substrate translocation pore; other site
696406012484	sensory histidine kinase UhpB; Provisional; Region: PRK11644
696406012485	MASE1; Region: MASE1; pfam05231
696406012486	Histidine kinase; Region: HisKA_3; pfam07730
696406012487	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
696406012488	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406012489	active site
696406012490	phosphorylation site [posttranslational modification]
696406012491	intermolecular recognition site; other site
696406012492	dimerization interface [polypeptide binding]; other site
696406012493	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
696406012494	DNA binding residues [nucleotide binding]
696406012495	dimerization interface [polypeptide binding]; other site
696406012496	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
696406012497	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
696406012498	putative valine binding site [chemical binding]; other site
696406012499	dimer interface [polypeptide binding]; other site
696406012500	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
696406012501	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
696406012502	PYR/PP interface [polypeptide binding]; other site
696406012503	dimer interface [polypeptide binding]; other site
696406012504	TPP binding site [chemical binding]; other site
696406012505	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
696406012506	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
696406012507	TPP-binding site [chemical binding]; other site
696406012508	dimer interface [polypeptide binding]; other site
696406012509	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
696406012510	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406012511	putative substrate translocation pore; other site
696406012512	Arylsulfatase regulator (Fe-S oxidoreductase) [General function prediction only]; Region: AslB; COG0641
696406012513	Domain of unknown function (DUF202); Region: DUF202; pfam02656
696406012514	Predicted membrane protein [Function unknown]; Region: COG2149
696406012515	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
696406012516	Sulfatase; Region: Sulfatase; pfam00884
696406012517	putative transporter; Provisional; Region: PRK10484
696406012518	uncharacterized SLC5 subfamily, Escherichia coli YidK-like; solute binding domain; Region: SLC5sbd_YidK; cd10328
696406012519	Na binding site [ion binding]; other site
696406012520	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
696406012521	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406012522	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
696406012523	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
696406012524	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
696406012525	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
696406012526	NAD(P) binding site [chemical binding]; other site
696406012527	LDH/MDH dimer interface [polypeptide binding]; other site
696406012528	substrate binding site [chemical binding]; other site
696406012529	PTS system, alpha-glucoside-specific IIBC component; Region: PTS-IIBC-alpha; TIGR02005
696406012530	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
696406012531	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
696406012532	active site turn [active]
696406012533	phosphorylation site [posttranslational modification]
696406012534	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
696406012535	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
696406012536	DNA-binding site [nucleotide binding]; DNA binding site
696406012537	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
696406012538	putative transporter; Validated; Region: PRK03818
696406012539	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
696406012540	TrkA-C domain; Region: TrkA_C; pfam02080
696406012541	TrkA-C domain; Region: TrkA_C; pfam02080
696406012542	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
696406012543	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
696406012544	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
696406012545	putative dimer interface [polypeptide binding]; other site
696406012546	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
696406012547	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
696406012548	putative dimer interface [polypeptide binding]; other site
696406012549	hypothetical protein; Provisional; Region: PRK11616
696406012550	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
696406012551	putative oxidoreductase; Provisional; Region: PRK11445
696406012552	hypothetical protein; Provisional; Region: PRK07236
696406012553	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406012554	D-galactonate transporter; Region: 2A0114; TIGR00893
696406012555	putative substrate translocation pore; other site
696406012556	galactonate dehydratase; Provisional; Region: PRK14017
696406012557	D-galactonate dehydratase catalyses the dehydration of galactonate to 2-keto-3-deoxygalactnate (KDGal), as part of the D-galactonate nonphosphorolytic catabolic Entner-Doudoroff pathway. D-galactonate dehydratase belongs to the enolase superfamily of...; Region: D-galactonate_dehydratase; cd03325
696406012558	putative active site pocket [active]
696406012559	putative metal binding site [ion binding]; other site
696406012560	2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Reviewed; Region: PRK09140
696406012561	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
696406012562	active site
696406012563	intersubunit interface [polypeptide binding]; other site
696406012564	catalytic residue [active]
696406012565	2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]; Region: DgoK; COG3734
696406012566	2-keto-3-deoxy-galactonokinase; Region: DGOK; pfam05035
696406012567	Transcriptional regulators [Transcription]; Region: FadR; COG2186
696406012568	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
696406012569	DNA-binding site [nucleotide binding]; DNA binding site
696406012570	FCD domain; Region: FCD; pfam07729
696406012571	hypothetical protein; Provisional; Region: PRK10215
696406012572	sugar phosphate phosphatase; Provisional; Region: PRK10513
696406012573	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696406012574	active site
696406012575	motif I; other site
696406012576	motif II; other site
696406012577	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696406012578	hypothetical protein; Provisional; Region: PRK11426
696406012579	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
696406012580	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406012581	Mg2+ binding site [ion binding]; other site
696406012582	G-X-G motif; other site
696406012583	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
696406012584	anchoring element; other site
696406012585	dimer interface [polypeptide binding]; other site
696406012586	ATP binding site [chemical binding]; other site
696406012587	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
696406012588	active site
696406012589	putative metal-binding site [ion binding]; other site
696406012590	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
696406012591	recF protein; Region: recf; TIGR00611
696406012592	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
696406012593	Walker A/P-loop; other site
696406012594	ATP binding site [chemical binding]; other site
696406012595	Q-loop/lid; other site
696406012596	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
696406012597	ABC transporter signature motif; other site
696406012598	Walker B; other site
696406012599	D-loop; other site
696406012600	H-loop/switch region; other site
696406012601	DNA polymerase III subunit beta; Validated; Region: PRK05643
696406012602	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
696406012603	putative DNA binding surface [nucleotide binding]; other site
696406012604	dimer interface [polypeptide binding]; other site
696406012605	beta-clamp/clamp loader binding surface; other site
696406012606	beta-clamp/translesion DNA polymerase binding surface; other site
696406012607	DnaA N-terminal domain; Region: DnaA_N; pfam11638
696406012608	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
696406012609	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406012610	Walker A motif; other site
696406012611	ATP binding site [chemical binding]; other site
696406012612	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
696406012613	Walker B motif; other site
696406012614	arginine finger; other site
696406012615	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
696406012616	DnaA box-binding interface [nucleotide binding]; other site
696406012617	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
696406012618	ribonuclease P; Reviewed; Region: rnpA; PRK01732
696406012619	membrane protein insertase; Provisional; Region: PRK01318
696406012620	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
696406012621	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
696406012622	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
696406012623	trmE is a tRNA modification GTPase; Region: trmE; cd04164
696406012624	G1 box; other site
696406012625	GTP/Mg2+ binding site [chemical binding]; other site
696406012626	Switch I region; other site
696406012627	G2 box; other site
696406012628	Switch II region; other site
696406012629	G3 box; other site
696406012630	G4 box; other site
696406012631	G5 box; other site
696406012632	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
696406012633	tryptophanase, leader peptide-associated; Region: tnaA_trp_ase; TIGR02617
696406012634	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
696406012635	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
696406012636	catalytic residue [active]
696406012637	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
696406012638	aromatic amino acid transport protein; Region: araaP; TIGR00837
696406012639	multidrug efflux system protein MdtL; Provisional; Region: PRK10473
696406012640	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406012641	putative substrate translocation pore; other site
696406012642	DNA-binding transcriptional regulator YidZ; Provisional; Region: PRK10216
696406012643	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406012644	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
696406012645	substrate binding pocket [chemical binding]; other site
696406012646	dimerization interface [polypeptide binding]; other site
696406012647	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
696406012648	Predicted flavoprotein [General function prediction only]; Region: COG0431
696406012649	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
696406012650	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
696406012651	6-phosphogluconate phosphatase; Provisional; Region: PRK10563
696406012652	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696406012653	active site
696406012654	motif I; other site
696406012655	motif II; other site
696406012656	putative inner membrane protein; Provisional; Region: PRK09823
696406012657	Uncharacterized protein family (UPF0167); Region: UPF0167; cl01252
696406012658	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
696406012659	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
696406012660	active site
696406012661	trimer interface [polypeptide binding]; other site
696406012662	allosteric site; other site
696406012663	active site lid [active]
696406012664	N-terminal Early set domain associated with the catalytic domain of putative esterases; Region: E_set_Esterase_like_N; cd11294
696406012665	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
696406012666	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
696406012667	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
696406012668	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
696406012669	trimer interface; other site
696406012670	sugar binding site [chemical binding]; other site
696406012671	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
696406012672	beta-galactosidase; Region: BGL; TIGR03356
696406012673	transcriptional antiterminator BglG; Provisional; Region: PRK09772
696406012674	CAT RNA binding domain; Region: CAT_RBD; pfam03123
696406012675	PRD domain; Region: PRD; pfam00874
696406012676	PRD domain; Region: PRD; pfam00874
696406012677	transcriptional regulator PhoU; Provisional; Region: PRK11115
696406012678	PhoU domain; Region: PhoU; pfam01895
696406012679	PhoU domain; Region: PhoU; pfam01895
696406012680	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
696406012681	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
696406012682	Walker A/P-loop; other site
696406012683	ATP binding site [chemical binding]; other site
696406012684	Q-loop/lid; other site
696406012685	ABC transporter signature motif; other site
696406012686	Walker B; other site
696406012687	D-loop; other site
696406012688	H-loop/switch region; other site
696406012689	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
696406012690	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406012691	dimer interface [polypeptide binding]; other site
696406012692	conserved gate region; other site
696406012693	putative PBP binding loops; other site
696406012694	ABC-ATPase subunit interface; other site
696406012695	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
696406012696	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406012697	dimer interface [polypeptide binding]; other site
696406012698	conserved gate region; other site
696406012699	putative PBP binding loops; other site
696406012700	ABC-ATPase subunit interface; other site
696406012701	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
696406012702	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
696406012703	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
696406012704	glutaminase active site [active]
696406012705	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
696406012706	dimer interface [polypeptide binding]; other site
696406012707	active site
696406012708	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
696406012709	dimer interface [polypeptide binding]; other site
696406012710	active site
696406012711	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
696406012712	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
696406012713	Substrate binding site; other site
696406012714	Mg++ binding site; other site
696406012715	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
696406012716	active site
696406012717	substrate binding site [chemical binding]; other site
696406012718	CoA binding site [chemical binding]; other site
696406012719	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
696406012720	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
696406012721	gamma subunit interface [polypeptide binding]; other site
696406012722	epsilon subunit interface [polypeptide binding]; other site
696406012723	LBP interface [polypeptide binding]; other site
696406012724	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
696406012725	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
696406012726	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
696406012727	alpha subunit interaction interface [polypeptide binding]; other site
696406012728	Walker A motif; other site
696406012729	ATP binding site [chemical binding]; other site
696406012730	Walker B motif; other site
696406012731	inhibitor binding site; inhibition site
696406012732	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
696406012733	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
696406012734	core domain interface [polypeptide binding]; other site
696406012735	delta subunit interface [polypeptide binding]; other site
696406012736	epsilon subunit interface [polypeptide binding]; other site
696406012737	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
696406012738	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
696406012739	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
696406012740	beta subunit interaction interface [polypeptide binding]; other site
696406012741	Walker A motif; other site
696406012742	ATP binding site [chemical binding]; other site
696406012743	Walker B motif; other site
696406012744	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
696406012745	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
696406012746	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
696406012747	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
696406012748	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
696406012749	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
696406012750	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
696406012751	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
696406012752	ATP synthase I chain; Region: ATP_synt_I; cl09170
696406012753	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
696406012754	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406012755	S-adenosylmethionine binding site [chemical binding]; other site
696406012756	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
696406012757	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
696406012758	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
696406012759	FMN-binding protein MioC; Provisional; Region: PRK09004
696406012760	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
696406012761	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
696406012762	putative DNA binding site [nucleotide binding]; other site
696406012763	putative Zn2+ binding site [ion binding]; other site
696406012764	AsnC family; Region: AsnC_trans_reg; pfam01037
696406012765	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
696406012766	dimer interface [polypeptide binding]; other site
696406012767	active site
696406012768	hypothetical protein; Provisional; Region: yieM; PRK10997
696406012769	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
696406012770	metal ion-dependent adhesion site (MIDAS); other site
696406012771	regulatory ATPase RavA; Provisional; Region: PRK13531
696406012772	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406012773	Walker A motif; other site
696406012774	ATP binding site [chemical binding]; other site
696406012775	Walker B motif; other site
696406012776	arginine finger; other site
696406012777	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
696406012778	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
696406012779	potassium uptake protein; Region: kup; TIGR00794
696406012780	D-ribose pyranase; Provisional; Region: PRK11797
696406012781	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
696406012782	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
696406012783	Walker A/P-loop; other site
696406012784	ATP binding site [chemical binding]; other site
696406012785	Q-loop/lid; other site
696406012786	ABC transporter signature motif; other site
696406012787	Walker B; other site
696406012788	D-loop; other site
696406012789	H-loop/switch region; other site
696406012790	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
696406012791	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
696406012792	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
696406012793	TM-ABC transporter signature motif; other site
696406012794	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
696406012795	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
696406012796	ligand binding site [chemical binding]; other site
696406012797	dimerization interface [polypeptide binding]; other site
696406012798	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
696406012799	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
696406012800	substrate binding site [chemical binding]; other site
696406012801	dimer interface [polypeptide binding]; other site
696406012802	ATP binding site [chemical binding]; other site
696406012803	transcriptional repressor RbsR; Provisional; Region: PRK10423
696406012804	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
696406012805	DNA binding site [nucleotide binding]
696406012806	domain linker motif; other site
696406012807	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
696406012808	dimerization interface [polypeptide binding]; other site
696406012809	ligand binding site [chemical binding]; other site
696406012810	putative transporter; Provisional; Region: PRK10504
696406012811	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406012812	putative substrate translocation pore; other site
696406012813	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406012814	Transcriptional regulators [Transcription]; Region: FadR; COG2186
696406012815	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
696406012816	DNA-binding site [nucleotide binding]; DNA binding site
696406012817	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
696406012818	transcriptional regulator HdfR; Provisional; Region: PRK03601
696406012819	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406012820	LysR substrate binding domain; Region: LysR_substrate; pfam03466
696406012821	dimerization interface [polypeptide binding]; other site
696406012822	hypothetical protein; Provisional; Region: PRK11027
696406012823	putative ATP-dependent protease; Provisional; Region: PRK09862
696406012824	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
696406012825	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406012826	Walker A motif; other site
696406012827	ATP binding site [chemical binding]; other site
696406012828	Walker B motif; other site
696406012829	arginine finger; other site
696406012830	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
696406012831	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
696406012832	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
696406012833	PYR/PP interface [polypeptide binding]; other site
696406012834	dimer interface [polypeptide binding]; other site
696406012835	TPP binding site [chemical binding]; other site
696406012836	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
696406012837	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
696406012838	TPP-binding site [chemical binding]; other site
696406012839	dimer interface [polypeptide binding]; other site
696406012840	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
696406012841	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
696406012842	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
696406012843	homodimer interface [polypeptide binding]; other site
696406012844	substrate-cofactor binding pocket; other site
696406012845	catalytic residue [active]
696406012846	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
696406012847	threonine dehydratase; Reviewed; Region: PRK09224
696406012848	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
696406012849	tetramer interface [polypeptide binding]; other site
696406012850	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406012851	catalytic residue [active]
696406012852	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
696406012853	putative Ile/Val binding site [chemical binding]; other site
696406012854	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
696406012855	putative Ile/Val binding site [chemical binding]; other site
696406012856	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406012857	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
696406012858	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
696406012859	putative dimerization interface [polypeptide binding]; other site
696406012860	ketol-acid reductoisomerase; Validated; Region: PRK05225
696406012861	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
696406012862	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
696406012863	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
696406012864	peptidyl-prolyl cis-trans isomerase C; Provisional; Region: PRK15441
696406012865	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
696406012866	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3692
696406012867	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
696406012868	Part of AAA domain; Region: AAA_19; pfam13245
696406012869	Family description; Region: UvrD_C_2; pfam13538
696406012870	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
696406012871	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
696406012872	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
696406012873	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
696406012874	ATP binding site [chemical binding]; other site
696406012875	Mg++ binding site [ion binding]; other site
696406012876	motif III; other site
696406012877	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
696406012878	nucleotide binding region [chemical binding]; other site
696406012879	ATP-binding site [chemical binding]; other site
696406012880	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
696406012881	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
696406012882	catalytic residues [active]
696406012883	transcription termination factor Rho; Provisional; Region: rho; PRK09376
696406012884	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
696406012885	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
696406012886	RNA binding site [nucleotide binding]; other site
696406012887	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
696406012888	multimer interface [polypeptide binding]; other site
696406012889	Walker A motif; other site
696406012890	ATP binding site [chemical binding]; other site
696406012891	Walker B motif; other site
696406012892	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
696406012893	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
696406012894	Mg++ binding site [ion binding]; other site
696406012895	putative catalytic motif [active]
696406012896	substrate binding site [chemical binding]; other site
696406012897	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
696406012898	Chain length determinant protein; Region: Wzz; pfam02706
696406012899	UDP-N-acetylglucosamine 2-epimerase; Region: wecB; TIGR00236
696406012900	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
696406012901	homodimer interface [polypeptide binding]; other site
696406012902	active site
696406012903	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
696406012904	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
696406012905	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
696406012906	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
696406012907	dTDP-glucose 4,6-dehydratase; Provisional; Region: PRK10217
696406012908	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
696406012909	NAD binding site [chemical binding]; other site
696406012910	substrate binding site [chemical binding]; other site
696406012911	homodimer interface [polypeptide binding]; other site
696406012912	active site
696406012913	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
696406012914	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
696406012915	substrate binding site; other site
696406012916	tetramer interface; other site
696406012917	TDP-fucosamine acetyltransferase; Provisional; Region: PRK10975
696406012918	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
696406012919	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
696406012920	inhibitor-cofactor binding pocket; inhibition site
696406012921	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406012922	catalytic residue [active]
696406012923	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
696406012924	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
696406012925	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
696406012926	putative common antigen polymerase; Provisional; Region: PRK02975
696406012927	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
696406012928	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
696406012929	putative transport protein YifK; Provisional; Region: PRK10746
696406012930	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
696406012931	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
696406012932	FeS/SAM binding site; other site
696406012933	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
696406012934	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
696406012935	Sulfatase; Region: Sulfatase; pfam00884
696406012936	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
696406012937	HemY protein N-terminus; Region: HemY_N; pfam07219
696406012938	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959
696406012939	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
696406012940	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
696406012941	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
696406012942	active site
696406012943	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
696406012944	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
696406012945	domain interfaces; other site
696406012946	active site
696406012947	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
696406012948	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
696406012949	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
696406012950	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
696406012951	putative iron binding site [ion binding]; other site
696406012952	hypothetical protein; Provisional; Region: PRK09807
696406012953	Predicted small periplasmic lipoprotein [Cell motility and secretion]; Region: COG5567
696406012954	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
696406012955	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
696406012956	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
696406012957	hypothetical protein; Provisional; Region: PRK10963
696406012958	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
696406012959	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
696406012960	active site
696406012961	DNA binding site [nucleotide binding]
696406012962	Int/Topo IB signature motif; other site
696406012963	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
696406012964	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696406012965	motif II; other site
696406012966	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
696406012967	Part of AAA domain; Region: AAA_19; pfam13245
696406012968	Family description; Region: UvrD_C_2; pfam13538
696406012969	Predicted periplasmic protein [Function unknown]; Region: COG3698
696406012970	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
696406012971	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
696406012972	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
696406012973	Cl binding site [ion binding]; other site
696406012974	oligomer interface [polypeptide binding]; other site
696406012975	Protein of unknown function (DUF2628); Region: DUF2628; pfam10947
696406012976	hypothetical protein; Provisional; Region: PRK11371
696406012977	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
696406012978	EamA-like transporter family; Region: EamA; cl17759
696406012979	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
696406012980	CoenzymeA binding site [chemical binding]; other site
696406012981	subunit interaction site [polypeptide binding]; other site
696406012982	PHB binding site; other site
696406012983	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
696406012984	dimerization interface [polypeptide binding]; other site
696406012985	substrate binding site [chemical binding]; other site
696406012986	active site
696406012987	calcium binding site [ion binding]; other site
696406012988	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
696406012989	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
696406012990	ATP binding site [chemical binding]; other site
696406012991	putative Mg++ binding site [ion binding]; other site
696406012992	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
696406012993	nucleotide binding region [chemical binding]; other site
696406012994	ATP-binding site [chemical binding]; other site
696406012995	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
696406012996	Helicase and RNase D C-terminal; Region: HRDC; smart00341
696406012997	threonine efflux system; Provisional; Region: PRK10229
696406012998	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
696406012999	lysophospholipase L2; Provisional; Region: PRK10749
696406013000	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
696406013001	putative hydrolase; Provisional; Region: PRK10976
696406013002	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696406013003	active site
696406013004	motif I; other site
696406013005	motif II; other site
696406013006	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696406013007	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
696406013008	EamA-like transporter family; Region: EamA; pfam00892
696406013009	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
696406013010	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
696406013011	THF binding site; other site
696406013012	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
696406013013	substrate binding site [chemical binding]; other site
696406013014	THF binding site; other site
696406013015	zinc-binding site [ion binding]; other site
696406013016	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
696406013017	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406013018	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
696406013019	dimerization interface [polypeptide binding]; other site
696406013020	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
696406013021	Na binding site [ion binding]; other site
696406013022	allophanate hydrolase; Provisional; Region: PRK08186
696406013023	carbamate kinase; Reviewed; Region: PRK12686
696406013024	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
696406013025	putative substrate binding site [chemical binding]; other site
696406013026	nucleotide binding site [chemical binding]; other site
696406013027	nucleotide binding site [chemical binding]; other site
696406013028	homodimer interface [polypeptide binding]; other site
696406013029	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
696406013030	membrane protein FdrA; Validated; Region: PRK06091
696406013031	CoA binding domain; Region: CoA_binding; pfam02629
696406013032	CoA-ligase; Region: Ligase_CoA; pfam00549
696406013033	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
696406013034	Isochorismatase family; Region: Isochorismatase; pfam00857
696406013035	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
696406013036	catalytic triad [active]
696406013037	conserved cis-peptide bond; other site
696406013038	Dienelactone hydrolase family; Region: DLH; pfam01738
696406013039	BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840
696406013040	CotJB protein; Region: CotJB; pfam12652
696406013041	uridine phosphorylase; Provisional; Region: PRK11178
696406013042	uridine phosphorylase; Region: Uridine-psphlse; TIGR01718
696406013043	Tripartite tricarboxylate transporter TctA family; Region: TctA; cl00772
696406013044	Tripartite tricarboxylate transporter TctB family; Region: TctB; pfam07331
696406013045	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3181
696406013046	2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Reviewed; Region: PRK09140
696406013047	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
696406013048	active site
696406013049	intersubunit interface [polypeptide binding]; other site
696406013050	catalytic residue [active]
696406013051	2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]; Region: DgoK; COG3734
696406013052	2-keto-3-deoxy-galactonokinase; Region: DGOK; pfam05035
696406013053	Transcriptional regulator [Transcription]; Region: IclR; COG1414
696406013054	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
696406013055	Bacterial transcriptional regulator; Region: IclR; pfam01614
696406013056	DNA recombination protein RmuC; Provisional; Region: PRK10361
696406013057	RmuC family; Region: RmuC; pfam02646
696406013058	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
696406013059	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406013060	S-adenosylmethionine binding site [chemical binding]; other site
696406013061	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
696406013062	SCP-2 sterol transfer family; Region: SCP2; pfam02036
696406013063	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
696406013064	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
696406013065	twin arginine translocase protein A; Provisional; Region: tatA; PRK03554
696406013066	twin arginine translocase protein A; Provisional; Region: tatA; PRK00575
696406013067	sec-independent translocase; Provisional; Region: PRK01770
696406013068	sec-independent translocase; Provisional; Region: tatB; PRK00404
696406013069	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
696406013070	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
696406013071	active site
696406013072	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
696406013073	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
696406013074	KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); Region: KOW; cl00354
696406013075	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
696406013076	FMN reductase; Validated; Region: fre; PRK08051
696406013077	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
696406013078	FAD binding pocket [chemical binding]; other site
696406013079	FAD binding motif [chemical binding]; other site
696406013080	phosphate binding motif [ion binding]; other site
696406013081	beta-alpha-beta structure motif; other site
696406013082	NAD binding pocket [chemical binding]; other site
696406013083	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
696406013084	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
696406013085	dimer interface [polypeptide binding]; other site
696406013086	active site
696406013087	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
696406013088	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
696406013089	substrate binding site [chemical binding]; other site
696406013090	oxyanion hole (OAH) forming residues; other site
696406013091	trimer interface [polypeptide binding]; other site
696406013092	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
696406013093	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
696406013094	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
696406013095	proline dipeptidase; Provisional; Region: PRK13607
696406013096	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
696406013097	active site
696406013098	hypothetical protein; Provisional; Region: PRK11568
696406013099	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
696406013100	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
696406013101	potassium transporter; Provisional; Region: PRK10750
696406013102	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
696406013103	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
696406013104	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
696406013105	Walker A motif; other site
696406013106	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
696406013107	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
696406013108	GTP binding site; other site
696406013109	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
696406013110	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
696406013111	serine/threonine protein kinase; Provisional; Region: PRK11768
696406013112	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
696406013113	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
696406013114	catalytic residues [active]
696406013115	hinge region; other site
696406013116	alpha helical domain; other site
696406013117	hypothetical protein; Provisional; Region: PRK11367
696406013118	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
696406013119	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
696406013120	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
696406013121	putative acyl-acceptor binding pocket; other site
696406013122	DNA polymerase I; Provisional; Region: PRK05755
696406013123	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
696406013124	active site
696406013125	metal binding site 1 [ion binding]; metal-binding site
696406013126	putative 5' ssDNA interaction site; other site
696406013127	metal binding site 3; metal-binding site
696406013128	metal binding site 2 [ion binding]; metal-binding site
696406013129	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
696406013130	putative DNA binding site [nucleotide binding]; other site
696406013131	putative metal binding site [ion binding]; other site
696406013132	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
696406013133	active site
696406013134	catalytic site [active]
696406013135	substrate binding site [chemical binding]; other site
696406013136	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
696406013137	active site
696406013138	DNA binding site [nucleotide binding]
696406013139	catalytic site [active]
696406013140	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
696406013141	G1 box; other site
696406013142	GTP/Mg2+ binding site [chemical binding]; other site
696406013143	Switch I region; other site
696406013144	G2 box; other site
696406013145	G3 box; other site
696406013146	Switch II region; other site
696406013147	G4 box; other site
696406013148	G5 box; other site
696406013149	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3078
696406013150	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
696406013151	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
696406013152	FeS/SAM binding site; other site
696406013153	HemN C-terminal domain; Region: HemN_C; pfam06969
696406013154	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
696406013155	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406013156	active site
696406013157	phosphorylation site [posttranslational modification]
696406013158	intermolecular recognition site; other site
696406013159	dimerization interface [polypeptide binding]; other site
696406013160	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406013161	Walker A motif; other site
696406013162	ATP binding site [chemical binding]; other site
696406013163	Walker B motif; other site
696406013164	arginine finger; other site
696406013165	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
696406013166	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
696406013167	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
696406013168	putative active site [active]
696406013169	heme pocket [chemical binding]; other site
696406013170	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
696406013171	dimer interface [polypeptide binding]; other site
696406013172	phosphorylation site [posttranslational modification]
696406013173	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406013174	ATP binding site [chemical binding]; other site
696406013175	Mg2+ binding site [ion binding]; other site
696406013176	G-X-G motif; other site
696406013177	glutamine synthetase; Provisional; Region: glnA; PRK09469
696406013178	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
696406013179	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
696406013180	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
696406013181	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
696406013182	G1 box; other site
696406013183	putative GEF interaction site [polypeptide binding]; other site
696406013184	GTP/Mg2+ binding site [chemical binding]; other site
696406013185	Switch I region; other site
696406013186	G2 box; other site
696406013187	G3 box; other site
696406013188	Switch II region; other site
696406013189	G4 box; other site
696406013190	G5 box; other site
696406013191	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
696406013192	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
696406013193	transcriptional regulator protein; Region: phnR; TIGR03337
696406013194	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
696406013195	DNA-binding site [nucleotide binding]; DNA binding site
696406013196	UTRA domain; Region: UTRA; pfam07702
696406013197	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
696406013198	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406013199	putative substrate translocation pore; other site
696406013200	phosphoglycerate transporter family protein; Region: 2A0104; TIGR00881
696406013201	outer membrane porin L; Provisional; Region: ompL; PRK09980
696406013202	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
696406013203	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406013204	putative substrate translocation pore; other site
696406013205	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
696406013206	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406013207	alpha-glucosidase; Provisional; Region: PRK10426
696406013208	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
696406013209	YihQ is a bacterial alpha-glucosidase with a conserved glycosyl hydrolase family 31 (GH31) domain that catalyzes the release of an alpha-glucosyl residue from the non-reducing end of alpha-glucoside substrates such as alpha-glucosyl fluoride. Orthologs...; Region: GH31_glucosidase_YihQ; cd06594
696406013210	putative active site [active]
696406013211	putative catalytic site [active]
696406013212	Aldose 1-epimerase, similar to Escherichia coli YihR; Region: Aldose_epim_Ec_YihR; cd09022
696406013213	active site
696406013214	catalytic residues [active]
696406013215	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cd00249
696406013216	dimerization interface [polypeptide binding]; other site
696406013217	putative active cleft [active]
696406013218	Tagatose-1,6-bisphosphate aldolase [Carbohydrate transport and metabolism]; Region: LacD; COG3684
696406013219	catalytic residue [active]
696406013220	NADH-dependent gamma-hydroxybutyrate dehydrogenase; Provisional; Region: PRK15461
696406013221	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
696406013222	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
696406013223	Ribokinase-like subgroup B.  Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_B; cd01945
696406013224	substrate binding site [chemical binding]; other site
696406013225	ATP binding site [chemical binding]; other site
696406013226	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
696406013227	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
696406013228	putative DNA binding site [nucleotide binding]; other site
696406013229	putative Zn2+ binding site [ion binding]; other site
696406013230	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
696406013231	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
696406013232	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696406013233	motif II; other site
696406013234	hypothetical protein; Reviewed; Region: PRK01637
696406013235	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
696406013236	putative active site [active]
696406013237	dimerization interface [polypeptide binding]; other site
696406013238	putative tRNAtyr binding site [nucleotide binding]; other site
696406013239	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
696406013240	Coenzyme A binding pocket [chemical binding]; other site
696406013241	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
696406013242	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
696406013243	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
696406013244	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
696406013245	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
696406013246	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
696406013247	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
696406013248	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
696406013249	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
696406013250	molybdopterin cofactor binding site; other site
696406013251	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
696406013252	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
696406013253	molybdopterin cofactor binding site; other site
696406013254	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
696406013255	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
696406013256	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
696406013257	putative frv operon regulatory protein; Provisional; Region: PRK09863
696406013258	HTH domain; Region: HTH_11; pfam08279
696406013259	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
696406013260	active site
696406013261	phosphorylation site [posttranslational modification]
696406013262	putative peptidase; Provisional; Region: PRK09864
696406013263	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
696406013264	oligomer interface [polypeptide binding]; other site
696406013265	active site
696406013266	metal binding site [ion binding]; metal-binding site
696406013267	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
696406013268	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
696406013269	active site
696406013270	P-loop; other site
696406013271	phosphorylation site [posttranslational modification]
696406013272	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
696406013273	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
696406013274	active site
696406013275	phosphorylation site [posttranslational modification]
696406013276	L-rhamnose 1-epimerase; Region: YiiL_rotase; TIGR02625
696406013277	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
696406013278	intersubunit interface [polypeptide binding]; other site
696406013279	active site
696406013280	Zn2+ binding site [ion binding]; other site
696406013281	L-rhamnose isomerase; Provisional; Region: PRK01076
696406013282	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
696406013283	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
696406013284	N- and C-terminal domain interface [polypeptide binding]; other site
696406013285	active site
696406013286	putative catalytic site [active]
696406013287	metal binding site [ion binding]; metal-binding site
696406013288	ATP binding site [chemical binding]; other site
696406013289	rhamnulokinase; Provisional; Region: rhaB; PRK10640
696406013290	carbohydrate binding site [chemical binding]; other site
696406013291	transcriptional activator RhaS; Provisional; Region: PRK13503
696406013292	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
696406013293	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406013294	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406013295	transcriptional activator RhaR; Provisional; Region: PRK13500
696406013296	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
696406013297	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406013298	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406013299	L-rhamnose-proton symport protein (RhaT); Region: RhaT; cl05728
696406013300	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
696406013301	superoxide dismutase; Provisional; Region: PRK10925
696406013302	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
696406013303	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
696406013304	RNA recognition motif (RRM) superfamily; Region: RRM_SF; cl17169
696406013305	2-keto-3-deoxygluconate transporter; Region: kdgT; TIGR00793
696406013306	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
696406013307	MOSC domain; Region: MOSC; pfam03473
696406013308	3-alpha domain; Region: 3-alpha; pfam03475
696406013309	two-component sensor protein; Provisional; Region: cpxA; PRK09470
696406013310	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
696406013311	dimerization interface [polypeptide binding]; other site
696406013312	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
696406013313	dimer interface [polypeptide binding]; other site
696406013314	phosphorylation site [posttranslational modification]
696406013315	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406013316	ATP binding site [chemical binding]; other site
696406013317	Mg2+ binding site [ion binding]; other site
696406013318	G-X-G motif; other site
696406013319	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
696406013320	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406013321	intermolecular recognition site; other site
696406013322	active site
696406013323	dimerization interface [polypeptide binding]; other site
696406013324	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
696406013325	DNA binding site [nucleotide binding]
696406013326	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
696406013327	dimer interface [polypeptide binding]; other site
696406013328	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
696406013329	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
696406013330	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
696406013331	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
696406013332	active site
696406013333	ADP/pyrophosphate binding site [chemical binding]; other site
696406013334	dimerization interface [polypeptide binding]; other site
696406013335	allosteric effector site; other site
696406013336	fructose-1,6-bisphosphate binding site; other site
696406013337	sulfate transporter subunit; Provisional; Region: PRK10752
696406013338	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
696406013339	CDP-diacylglycerol pyrophosphatase, bacterial type; Region: cdh; TIGR00672
696406013340	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
696406013341	triosephosphate isomerase; Provisional; Region: PRK14567
696406013342	substrate binding site [chemical binding]; other site
696406013343	dimer interface [polypeptide binding]; other site
696406013344	catalytic triad [active]
696406013345	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
696406013346	Predicted membrane protein [Function unknown]; Region: COG3152
696406013347	hypothetical protein; Provisional; Region: PRK09981
696406013348	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
696406013349	Ligand Binding Site [chemical binding]; other site
696406013350	ferredoxin-NADP reductase; Provisional; Region: PRK10926
696406013351	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
696406013352	FAD binding pocket [chemical binding]; other site
696406013353	FAD binding motif [chemical binding]; other site
696406013354	phosphate binding motif [ion binding]; other site
696406013355	beta-alpha-beta structure motif; other site
696406013356	NAD binding pocket [chemical binding]; other site
696406013357	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
696406013358	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
696406013359	putative active site [active]
696406013360	glycerol kinase; Provisional; Region: glpK; PRK00047
696406013361	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
696406013362	N- and C-terminal domain interface [polypeptide binding]; other site
696406013363	active site
696406013364	MgATP binding site [chemical binding]; other site
696406013365	catalytic site [active]
696406013366	metal binding site [ion binding]; metal-binding site
696406013367	glycerol binding site [chemical binding]; other site
696406013368	homotetramer interface [polypeptide binding]; other site
696406013369	homodimer interface [polypeptide binding]; other site
696406013370	FBP binding site [chemical binding]; other site
696406013371	protein IIAGlc interface [polypeptide binding]; other site
696406013372	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
696406013373	amphipathic channel; other site
696406013374	Asn-Pro-Ala signature motifs; other site
696406013375	septal ring assembly protein ZapB; Provisional; Region: PRK15422
696406013376	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
696406013377	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Region: menA; TIGR00751
696406013378	UbiA prenyltransferase family; Region: UbiA; pfam01040
696406013379	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
696406013380	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406013381	Walker A motif; other site
696406013382	ATP binding site [chemical binding]; other site
696406013383	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
696406013384	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
696406013385	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
696406013386	active site
696406013387	HslU subunit interaction site [polypeptide binding]; other site
696406013388	essential cell division protein FtsN; Provisional; Region: PRK10927
696406013389	cell division protein FtsN; Provisional; Region: PRK12757
696406013390	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
696406013391	DNA binding site [nucleotide binding]
696406013392	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
696406013393	domain linker motif; other site
696406013394	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
696406013395	dimerization interface [polypeptide binding]; other site
696406013396	ligand binding site [chemical binding]; other site
696406013397	primosome assembly protein PriA; Validated; Region: PRK05580
696406013398	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
696406013399	ATP binding site [chemical binding]; other site
696406013400	putative Mg++ binding site [ion binding]; other site
696406013401	helicase superfamily c-terminal domain; Region: HELICc; smart00490
696406013402	ATP-binding site [chemical binding]; other site
696406013403	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
696406013404	hypothetical protein; Provisional; Region: PRK10030
696406013405	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
696406013406	dimerization interface [polypeptide binding]; other site
696406013407	DNA binding site [nucleotide binding]
696406013408	corepressor binding sites; other site
696406013409	cystathionine gamma-synthase; Provisional; Region: PRK08045
696406013410	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
696406013411	homodimer interface [polypeptide binding]; other site
696406013412	substrate-cofactor binding pocket; other site
696406013413	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406013414	catalytic residue [active]
696406013415	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
696406013416	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
696406013417	putative catalytic residues [active]
696406013418	putative nucleotide binding site [chemical binding]; other site
696406013419	putative aspartate binding site [chemical binding]; other site
696406013420	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
696406013421	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
696406013422	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
696406013423	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
696406013424	FAD binding site [chemical binding]; other site
696406013425	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
696406013426	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
696406013427	heme binding site [chemical binding]; other site
696406013428	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
696406013429	EamA-like transporter family; Region: EamA; pfam00892
696406013430	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
696406013431	EamA-like transporter family; Region: EamA; pfam00892
696406013432	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3738
696406013433	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
696406013434	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
696406013435	dimer interface [polypeptide binding]; other site
696406013436	active site
696406013437	metal binding site [ion binding]; metal-binding site
696406013438	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
696406013439	active site
696406013440	intersubunit interactions; other site
696406013441	catalytic residue [active]
696406013442	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
696406013443	dimerization domain swap beta strand [polypeptide binding]; other site
696406013444	regulatory protein interface [polypeptide binding]; other site
696406013445	active site
696406013446	regulatory phosphorylation site [posttranslational modification]; other site
696406013447	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
696406013448	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
696406013449	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
696406013450	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
696406013451	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
696406013452	active site
696406013453	phosphorylation site [posttranslational modification]
696406013454	putative PTS system fructose-like transporter subunit EIIC; Provisional; Region: PRK10478
696406013455	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
696406013456	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
696406013457	active site
696406013458	P-loop; other site
696406013459	phosphorylation site [posttranslational modification]
696406013460	putative formate acetyltransferase 2; Provisional; Region: pflD; PRK09983
696406013461	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
696406013462	dimer interface [polypeptide binding]; other site
696406013463	active site
696406013464	glycine loop; other site
696406013465	pyruvate formate lyase II activase; Provisional; Region: PRK10076
696406013466	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
696406013467	active site
696406013468	P-loop; other site
696406013469	phosphorylation site [posttranslational modification]
696406013470	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
696406013471	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406013472	hypothetical protein; Provisional; Region: PRK10649
696406013473	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
696406013474	Sulfatase; Region: Sulfatase; pfam00884
696406013475	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
696406013476	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
696406013477	acetylornithine deacetylase; Provisional; Region: PRK05111
696406013478	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
696406013479	metal binding site [ion binding]; metal-binding site
696406013480	putative dimer interface [polypeptide binding]; other site
696406013481	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
696406013482	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
696406013483	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
696406013484	nucleotide binding site [chemical binding]; other site
696406013485	N-acetyl-L-glutamate binding site [chemical binding]; other site
696406013486	argininosuccinate lyase; Provisional; Region: PRK04833
696406013487	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
696406013488	active sites [active]
696406013489	tetramer interface [polypeptide binding]; other site
696406013490	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
696406013491	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406013492	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
696406013493	dimerization interface [polypeptide binding]; other site
696406013494	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
696406013495	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
696406013496	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
696406013497	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
696406013498	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
696406013499	hypothetical protein; Provisional; Region: PRK11056
696406013500	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
696406013501	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406013502	S-adenosylmethionine binding site [chemical binding]; other site
696406013503	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
696406013504	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
696406013505	N-terminal plug; other site
696406013506	ligand-binding site [chemical binding]; other site
696406013507	glutamate racemase; Provisional; Region: PRK00865
696406013508	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
696406013509	FAD binding domain; Region: FAD_binding_4; pfam01565
696406013510	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
696406013511	Biotin operon repressor [Transcription]; Region: BirA; COG1654
696406013512	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
696406013513	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
696406013514	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
696406013515	pantothenate kinase; Provisional; Region: PRK05439
696406013516	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
696406013517	ATP-binding site [chemical binding]; other site
696406013518	CoA-binding site [chemical binding]; other site
696406013519	Mg2+-binding site [ion binding]; other site
696406013520	elongation factor Tu; Reviewed; Region: PRK00049
696406013521	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
696406013522	G1 box; other site
696406013523	GEF interaction site [polypeptide binding]; other site
696406013524	GTP/Mg2+ binding site [chemical binding]; other site
696406013525	Switch I region; other site
696406013526	G2 box; other site
696406013527	G3 box; other site
696406013528	Switch II region; other site
696406013529	G4 box; other site
696406013530	G5 box; other site
696406013531	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
696406013532	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
696406013533	Antibiotic Binding Site [chemical binding]; other site
696406013534	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
696406013535	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
696406013536	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
696406013537	putative homodimer interface [polypeptide binding]; other site
696406013538	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
696406013539	heterodimer interface [polypeptide binding]; other site
696406013540	homodimer interface [polypeptide binding]; other site
696406013541	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
696406013542	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
696406013543	23S rRNA interface [nucleotide binding]; other site
696406013544	L7/L12 interface [polypeptide binding]; other site
696406013545	putative thiostrepton binding site; other site
696406013546	L25 interface [polypeptide binding]; other site
696406013547	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
696406013548	mRNA/rRNA interface [nucleotide binding]; other site
696406013549	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
696406013550	23S rRNA interface [nucleotide binding]; other site
696406013551	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
696406013552	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
696406013553	core dimer interface [polypeptide binding]; other site
696406013554	peripheral dimer interface [polypeptide binding]; other site
696406013555	L10 interface [polypeptide binding]; other site
696406013556	L11 interface [polypeptide binding]; other site
696406013557	putative EF-Tu interaction site [polypeptide binding]; other site
696406013558	putative EF-G interaction site [polypeptide binding]; other site
696406013559	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
696406013560	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
696406013561	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
696406013562	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
696406013563	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
696406013564	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
696406013565	RPB3 interaction site [polypeptide binding]; other site
696406013566	RPB1 interaction site [polypeptide binding]; other site
696406013567	RPB11 interaction site [polypeptide binding]; other site
696406013568	RPB10 interaction site [polypeptide binding]; other site
696406013569	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
696406013570	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
696406013571	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
696406013572	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
696406013573	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
696406013574	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
696406013575	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
696406013576	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
696406013577	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
696406013578	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
696406013579	DNA binding site [nucleotide binding]
696406013580	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
696406013581	stationary phase growth adaptation protein; Provisional; Region: PRK09717
696406013582	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
696406013583	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
696406013584	FeS/SAM binding site; other site
696406013585	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
696406013586	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
696406013587	ThiS interaction site; other site
696406013588	putative active site [active]
696406013589	tetramer interface [polypeptide binding]; other site
696406013590	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
696406013591	thiS-thiF/thiG interaction site; other site
696406013592	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
696406013593	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
696406013594	ATP binding site [chemical binding]; other site
696406013595	substrate interface [chemical binding]; other site
696406013596	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
696406013597	thiamine phosphate binding site [chemical binding]; other site
696406013598	active site
696406013599	pyrophosphate binding site [ion binding]; other site
696406013600	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
696406013601	ThiC-associated domain; Region: ThiC-associated; pfam13667
696406013602	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
696406013603	Regulator of sigma D [Transcription]; Region: Rsd; COG3160
696406013604	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
696406013605	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
696406013606	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
696406013607	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
696406013608	putative NADH binding site [chemical binding]; other site
696406013609	putative active site [active]
696406013610	nudix motif; other site
696406013611	putative metal binding site [ion binding]; other site
696406013612	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
696406013613	substrate binding site [chemical binding]; other site
696406013614	active site
696406013615	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
696406013616	Active_site [active]
696406013617	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
696406013618	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
696406013619	IHF dimer interface [polypeptide binding]; other site
696406013620	IHF - DNA interface [nucleotide binding]; other site
696406013621	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
696406013622	zinc resistance protein; Provisional; Region: zraP; PRK11546
696406013623	dimer interface [polypeptide binding]; other site
696406013624	sensor protein ZraS; Provisional; Region: PRK10364
696406013625	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
696406013626	dimer interface [polypeptide binding]; other site
696406013627	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406013628	ATP binding site [chemical binding]; other site
696406013629	Mg2+ binding site [ion binding]; other site
696406013630	G-X-G motif; other site
696406013631	transcriptional regulatory protein ZraR; Provisional; Region: PRK10365
696406013632	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406013633	active site
696406013634	phosphorylation site [posttranslational modification]
696406013635	intermolecular recognition site; other site
696406013636	dimerization interface [polypeptide binding]; other site
696406013637	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406013638	Walker A motif; other site
696406013639	ATP binding site [chemical binding]; other site
696406013640	Walker B motif; other site
696406013641	arginine finger; other site
696406013642	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
696406013643	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
696406013644	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
696406013645	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
696406013646	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
696406013647	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
696406013648	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
696406013649	purine monophosphate binding site [chemical binding]; other site
696406013650	dimer interface [polypeptide binding]; other site
696406013651	putative catalytic residues [active]
696406013652	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
696406013653	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
696406013654	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
696406013655	Coenzyme A binding pocket [chemical binding]; other site
696406013656	homoserine O-succinyltransferase; Provisional; Region: PRK05368
696406013657	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
696406013658	proposed active site lysine [active]
696406013659	conserved cys residue [active]
696406013660	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
696406013661	malate synthase A; Region: malate_syn_A; TIGR01344
696406013662	active site
696406013663	isocitrate lyase; Provisional; Region: PRK15063
696406013664	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
696406013665	tetramer interface [polypeptide binding]; other site
696406013666	active site
696406013667	Mg2+/Mn2+ binding site [ion binding]; other site
696406013668	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
696406013669	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
696406013670	ShET2 enterotoxin, N-terminal region; Region: Toxin_15; pfam07906
696406013671	transcriptional repressor IclR; Provisional; Region: PRK11569
696406013672	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
696406013673	Bacterial transcriptional regulator; Region: IclR; pfam01614
696406013674	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
696406013675	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
696406013676	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
696406013677	substrate binding pocket [chemical binding]; other site
696406013678	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
696406013679	B12 binding site [chemical binding]; other site
696406013680	cobalt ligand [ion binding]; other site
696406013681	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
696406013682	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
696406013683	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
696406013684	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
696406013685	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
696406013686	active site pocket [active]
696406013687	oxyanion hole [active]
696406013688	catalytic triad [active]
696406013689	active site nucleophile [active]
696406013690	L-sorbose-1-phosphate reductase; Region: sorbose_phosphate_red; cd08238
696406013691	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
696406013692	putative NAD(P) binding site [chemical binding]; other site
696406013693	catalytic Zn binding site [ion binding]; other site
696406013694	PTS system, mannose/fructose/sorbose family, IID component; Region: EIID-AGA; TIGR00828
696406013695	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
696406013696	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
696406013697	active site
696406013698	phosphorylation site [posttranslational modification]
696406013699	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
696406013700	active pocket/dimerization site; other site
696406013701	active site
696406013702	phosphorylation site [posttranslational modification]
696406013703	sorbitol-6-phosphate 2-dehydrogenase; Provisional; Region: PRK06171
696406013704	classical (c) SDRs; Region: SDR_c; cd05233
696406013705	NAD(P) binding site [chemical binding]; other site
696406013706	active site
696406013707	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
696406013708	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
696406013709	putative DNA binding site [nucleotide binding]; other site
696406013710	putative Zn2+ binding site [ion binding]; other site
696406013711	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
696406013712	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
696406013713	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
696406013714	RNA binding surface [nucleotide binding]; other site
696406013715	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
696406013716	probable active site [active]
696406013717	hypothetical protein; Provisional; Region: PRK10515
696406013718	aspartate kinase III; Validated; Region: PRK09084
696406013719	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
696406013720	nucleotide binding site [chemical binding]; other site
696406013721	substrate binding site [chemical binding]; other site
696406013722	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_1; cd04932
696406013723	lysine allosteric regulatory site; other site
696406013724	dimer interface [polypeptide binding]; other site
696406013725	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
696406013726	dimer interface [polypeptide binding]; other site
696406013727	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
696406013728	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
696406013729	active site
696406013730	dimer interface [polypeptide binding]; other site
696406013731	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
696406013732	dimer interface [polypeptide binding]; other site
696406013733	active site
696406013734	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
696406013735	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
696406013736	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
696406013737	phosphate-starvation-inducible protein PsiE; Provisional; Region: PRK02833
696406013738	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
696406013739	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406013740	putative substrate translocation pore; other site
696406013741	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406013742	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
696406013743	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406013744	dimer interface [polypeptide binding]; other site
696406013745	conserved gate region; other site
696406013746	putative PBP binding loops; other site
696406013747	ABC-ATPase subunit interface; other site
696406013748	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406013749	dimer interface [polypeptide binding]; other site
696406013750	conserved gate region; other site
696406013751	putative PBP binding loops; other site
696406013752	ABC-ATPase subunit interface; other site
696406013753	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
696406013754	Domain of unknown function (DUF4179); Region: DUF4179; pfam13786
696406013755	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
696406013756	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
696406013757	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
696406013758	Walker A/P-loop; other site
696406013759	ATP binding site [chemical binding]; other site
696406013760	Q-loop/lid; other site
696406013761	ABC transporter signature motif; other site
696406013762	Walker B; other site
696406013763	D-loop; other site
696406013764	H-loop/switch region; other site
696406013765	TOBE domain; Region: TOBE_2; pfam08402
696406013766	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
696406013767	trimer interface; other site
696406013768	sugar binding site [chemical binding]; other site
696406013769	maltose regulon periplasmic protein; Provisional; Region: PRK10564
696406013770	hypothetical protein; Validated; Region: PRK09718
696406013771	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
696406013772	SopA-like central domain; Region: SopA; pfam13981
696406013773	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
696406013774	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
696406013775	UbiA prenyltransferase family; Region: UbiA; pfam01040
696406013776	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
696406013777	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
696406013778	putative acyl-acceptor binding pocket; other site
696406013779	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
696406013780	LexA repressor; Validated; Region: PRK00215
696406013781	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
696406013782	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
696406013783	Catalytic site [active]
696406013784	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
696406013785	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
696406013786	hypothetical protein; Provisional; Region: PRK10428
696406013787	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
696406013788	metal binding site 2 [ion binding]; metal-binding site
696406013789	putative DNA binding helix; other site
696406013790	metal binding site 1 [ion binding]; metal-binding site
696406013791	dimer interface [polypeptide binding]; other site
696406013792	structural Zn2+ binding site [ion binding]; other site
696406013793	Protein of unknown function (DUF2713); Region: DUF2713; pfam10897
696406013794	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
696406013795	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
696406013796	FMN binding site [chemical binding]; other site
696406013797	active site
696406013798	catalytic residues [active]
696406013799	substrate binding site [chemical binding]; other site
696406013800	phage shock protein G; Reviewed; Region: pspG; PRK09459
696406013801	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
696406013802	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
696406013803	NADP binding site [chemical binding]; other site
696406013804	dimer interface [polypeptide binding]; other site
696406013805	replicative DNA helicase; Provisional; Region: PRK08006
696406013806	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
696406013807	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
696406013808	Walker A motif; other site
696406013809	ATP binding site [chemical binding]; other site
696406013810	Walker B motif; other site
696406013811	DNA binding loops [nucleotide binding]
696406013812	alanine racemase; Reviewed; Region: alr; PRK00053
696406013813	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
696406013814	active site
696406013815	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
696406013816	substrate binding site [chemical binding]; other site
696406013817	catalytic residues [active]
696406013818	dimer interface [polypeptide binding]; other site
696406013819	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
696406013820	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
696406013821	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406013822	homodimer interface [polypeptide binding]; other site
696406013823	catalytic residue [active]
696406013824	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696406013825	active site
696406013826	motif I; other site
696406013827	motif II; other site
696406013828	secondary thiamine-phosphate synthase enzyme; Region: TIGR00149_YjbQ
696406013829	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
696406013830	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
696406013831	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
696406013832	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
696406013833	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
696406013834	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
696406013835	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
696406013836	dimer interface [polypeptide binding]; other site
696406013837	ssDNA binding site [nucleotide binding]; other site
696406013838	tetramer (dimer of dimers) interface [polypeptide binding]; other site
696406013839	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
696406013840	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
696406013841	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
696406013842	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
696406013843	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
696406013844	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406013845	redox-sensitivie transcriptional activator SoxR; Provisional; Region: PRK15002
696406013846	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
696406013847	DNA binding residues [nucleotide binding]
696406013848	dimer interface [polypeptide binding]; other site
696406013849	[2Fe-2S] cluster binding site [ion binding]; other site
696406013850	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
696406013851	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
696406013852	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
696406013853	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
696406013854	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
696406013855	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
696406013856	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
696406013857	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
696406013858	Na binding site [ion binding]; other site
696406013859	Predicted membrane protein [Function unknown]; Region: COG3162
696406013860	acetyl-CoA synthetase; Provisional; Region: PRK00174
696406013861	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
696406013862	active site
696406013863	CoA binding site [chemical binding]; other site
696406013864	acyl-activating enzyme (AAE) consensus motif; other site
696406013865	AMP binding site [chemical binding]; other site
696406013866	acetate binding site [chemical binding]; other site
696406013867	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
696406013868	cytochrome c nitrite reductase pentaheme subunit; Provisional; Region: PRK11659
696406013869	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
696406013870	Formate-dependent nitrite reductase, membrane component [Inorganic ion transport and metabolism]; Region: NrfD; COG3301
696406013871	cytochrome c nitrite reductase, NrfD subunit; Region: cyt_nit_nrfD; TIGR03148
696406013872	heme lyase subunit NrfE; Provisional; Region: PRK10369
696406013873	formate-dependent nitrite reductase complex subunit NrfF; Provisional; Region: PRK10144
696406013874	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
696406013875	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
696406013876	binding surface
696406013877	TPR motif; other site
696406013878	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
696406013879	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
696406013880	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
696406013881	Sel1-like repeats; Region: SEL1; smart00671
696406013882	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
696406013883	molybdopterin cofactor binding site; other site
696406013884	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
696406013885	molybdopterin cofactor binding site; other site
696406013886	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
696406013887	putative outer membrane efflux protein MdtP; Provisional; Region: PRK09915
696406013888	multidrug efflux system protein MdtO; Provisional; Region: PRK11427
696406013889	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
696406013890	multidrug resistance protein MdtN; Provisional; Region: PRK10476
696406013891	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
696406013892	HlyD family secretion protein; Region: HlyD_3; pfam13437
696406013893	Alkyl sulfatase and related hydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2015
696406013894	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
696406013895	D-allose kinase; Provisional; Region: PRK09698
696406013896	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
696406013897	nucleotide binding site [chemical binding]; other site
696406013898	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
696406013899	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
696406013900	substrate binding site [chemical binding]; other site
696406013901	hexamer interface [polypeptide binding]; other site
696406013902	metal binding site [ion binding]; metal-binding site
696406013903	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
696406013904	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
696406013905	TM-ABC transporter signature motif; other site
696406013906	D-allose transporter ATP-binding protein; Provisional; Region: PRK09700
696406013907	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
696406013908	Walker A/P-loop; other site
696406013909	ATP binding site [chemical binding]; other site
696406013910	Q-loop/lid; other site
696406013911	ABC transporter signature motif; other site
696406013912	Walker B; other site
696406013913	D-loop; other site
696406013914	H-loop/switch region; other site
696406013915	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
696406013916	D-allose transporter subunit; Provisional; Region: PRK09701
696406013917	Periplasmic allose-binding domain of bacterial transport systems that function as a primary receptor of active transport and chemotaxis; Region: PBP1_allose_binding; cd06320
696406013918	ligand binding site [chemical binding]; other site
696406013919	dimerization interface [polypeptide binding]; other site
696406013920	zinc binding site [ion binding]; other site
696406013921	DNA-binding transcriptional repressor RpiR; Provisional; Region: PRK11337
696406013922	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
696406013923	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
696406013924	putative active site [active]
696406013925	ribose 5-phosphate isomerase B; Region: rpiB; TIGR01120
696406013926	carbon-phosphorus lyase complex accessory protein; Provisional; Region: phnP; PRK11244
696406013927	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
696406013928	Coenzyme A binding pocket [chemical binding]; other site
696406013929	ribose 1,5-bisphosphokinase; Provisional; Region: PRK10078
696406013930	AAA domain; Region: AAA_18; pfam13238
696406013931	active site
696406013932	phosphonate metabolism protein PhnM; Provisional; Region: PRK15446
696406013933	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
696406013934	PhnM is believed to be a subunit of the membrane associated C-P lyase complex. C-P lyase is thought to catalyze the direct cleavage of inactivated C-P bonds to yield inorganic phosphate and the corresponding hydrocarbons. It is responsible for cleavage...; Region: PhnM; cd01306
696406013935	active site
696406013936	ABC-type phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PhnL; COG4778
696406013937	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
696406013938	Walker A/P-loop; other site
696406013939	ATP binding site [chemical binding]; other site
696406013940	Q-loop/lid; other site
696406013941	ABC transporter signature motif; other site
696406013942	Walker B; other site
696406013943	D-loop; other site
696406013944	H-loop/switch region; other site
696406013945	phosphonate C-P lyase system protein PhnK; Provisional; Region: phnK; PRK11701
696406013946	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
696406013947	Walker A/P-loop; other site
696406013948	ATP binding site [chemical binding]; other site
696406013949	Q-loop/lid; other site
696406013950	ABC transporter signature motif; other site
696406013951	Walker B; other site
696406013952	D-loop; other site
696406013953	H-loop/switch region; other site
696406013954	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
696406013955	Bacterial phosphonate metabolism protein (PhnI); Region: PhnI; cl01456
696406013956	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnJ; COG3627
696406013957	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnH; COG3625
696406013958	Phosphonate metabolism protein PhnG; Region: PhnG; pfam06754
696406013959	phosphonate metabolism transcriptional regulator PhnF; Provisional; Region: PRK10079
696406013960	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
696406013961	DNA-binding site [nucleotide binding]; DNA binding site
696406013962	UTRA domain; Region: UTRA; pfam07702
696406013963	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
696406013964	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
696406013965	dimer interface [polypeptide binding]; other site
696406013966	conserved gate region; other site
696406013967	putative PBP binding loops; other site
696406013968	ABC-ATPase subunit interface; other site
696406013969	phosphonate ABC transporter, periplasmic phosphonate binding protein; Region: PhnD; TIGR03431
696406013970	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
696406013971	substrate binding pocket [chemical binding]; other site
696406013972	membrane-bound complex binding site; other site
696406013973	hinge residues; other site
696406013974	phosphonate/organophosphate ester transporter subunit; Provisional; Region: PRK09984
696406013975	ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Region: ABC_PhnC_transporter; cd03256
696406013976	Walker A/P-loop; other site
696406013977	ATP binding site [chemical binding]; other site
696406013978	Q-loop/lid; other site
696406013979	ABC transporter signature motif; other site
696406013980	Walker B; other site
696406013981	D-loop; other site
696406013982	H-loop/switch region; other site
696406013983	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
696406013984	dimer interface [polypeptide binding]; other site
696406013985	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
696406013986	hypothetical protein; Provisional; Region: PRK10220
696406013987	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
696406013988	PhnA protein; Region: PhnA; pfam03831
696406013989	hypothetical protein; Provisional; Region: PRK09866
696406013990	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
696406013991	G1 box; other site
696406013992	GTP/Mg2+ binding site [chemical binding]; other site
696406013993	G2 box; other site
696406013994	Switch I region; other site
696406013995	G3 box; other site
696406013996	Switch II region; other site
696406013997	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
696406013998	G2 box; other site
696406013999	Switch I region; other site
696406014000	G3 box; other site
696406014001	Switch II region; other site
696406014002	G4 box; other site
696406014003	G5 box; other site
696406014004	YjcZ-like protein; Region: YjcZ; pfam13990
696406014005	proline/glycine betaine transporter; Provisional; Region: PRK10642
696406014006	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406014007	putative substrate translocation pore; other site
696406014008	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
696406014009	sensor protein BasS/PmrB; Provisional; Region: PRK10755
696406014010	HAMP domain; Region: HAMP; pfam00672
696406014011	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
696406014012	dimer interface [polypeptide binding]; other site
696406014013	phosphorylation site [posttranslational modification]
696406014014	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406014015	ATP binding site [chemical binding]; other site
696406014016	Mg2+ binding site [ion binding]; other site
696406014017	G-X-G motif; other site
696406014018	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
696406014019	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406014020	active site
696406014021	phosphorylation site [posttranslational modification]
696406014022	intermolecular recognition site; other site
696406014023	dimerization interface [polypeptide binding]; other site
696406014024	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
696406014025	DNA binding site [nucleotide binding]
696406014026	putative metal dependent hydrolase; Provisional; Region: PRK11598
696406014027	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
696406014028	Sulfatase; Region: Sulfatase; pfam00884
696406014029	arginine:agmatin antiporter; Provisional; Region: PRK10644
696406014030	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
696406014031	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406014032	arginine decarboxylase; Provisional; Region: PRK15029
696406014033	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
696406014034	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
696406014035	homodimer interface [polypeptide binding]; other site
696406014036	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406014037	catalytic residue [active]
696406014038	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
696406014039	DNA-binding transcriptional regulator MelR; Provisional; Region: PRK10371
696406014040	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406014041	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406014042	alpha-galactosidase; Provisional; Region: PRK15076
696406014043	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
696406014044	NAD binding site [chemical binding]; other site
696406014045	sugar binding site [chemical binding]; other site
696406014046	divalent metal binding site [ion binding]; other site
696406014047	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
696406014048	dimer interface [polypeptide binding]; other site
696406014049	melibiose:sodium symporter; Provisional; Region: PRK10429
696406014050	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
696406014051	hypothetical protein; Provisional; Region: PRK09867
696406014052	fumarate hydratase; Provisional; Region: PRK15389
696406014053	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
696406014054	Fumarase C-terminus; Region: Fumerase_C; pfam05683
696406014055	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
696406014056	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
696406014057	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
696406014058	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406014059	active site
696406014060	phosphorylation site [posttranslational modification]
696406014061	intermolecular recognition site; other site
696406014062	dimerization interface [polypeptide binding]; other site
696406014063	Transcriptional regulator; Region: CitT; pfam12431
696406014064	sensory histidine kinase DcuS; Provisional; Region: PRK11086
696406014065	PAS domain; Region: PAS; smart00091
696406014066	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406014067	ATP binding site [chemical binding]; other site
696406014068	Mg2+ binding site [ion binding]; other site
696406014069	G-X-G motif; other site
696406014070	Uncharacterized conserved protein [Function unknown]; Region: COG3592
696406014071	Predicted acetyltransferase [General function prediction only]; Region: COG2388
696406014072	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
696406014073	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
696406014074	lysyl-tRNA synthetase; Reviewed; Region: PRK12445
696406014075	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
696406014076	dimer interface [polypeptide binding]; other site
696406014077	putative anticodon binding site; other site
696406014078	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
696406014079	motif 1; other site
696406014080	active site
696406014081	motif 2; other site
696406014082	motif 3; other site
696406014083	POT family; Region: PTR2; cl17359
696406014084	POT family; Region: PTR2; cl17359
696406014085	lysine decarboxylase CadA; Provisional; Region: PRK15400
696406014086	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
696406014087	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
696406014088	homodimer interface [polypeptide binding]; other site
696406014089	pyridoxal 5'-phosphate binding site [chemical binding]; other site
696406014090	catalytic residue [active]
696406014091	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
696406014092	lysine/cadaverine antiporter; Provisional; Region: cadB; PRK10435
696406014093	DNA-binding transcriptional activator CadC; Provisional; Region: PRK10153
696406014094	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
696406014095	DNA binding site [nucleotide binding]
696406014096	AAA domain; Region: AAA_31; pfam13614
696406014097	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
696406014098	P-loop; other site
696406014099	Magnesium ion binding site [ion binding]; other site
696406014100	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
696406014101	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
696406014102	replicative DNA helicase; Region: DnaB; TIGR00665
696406014103	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
696406014104	Walker A motif; other site
696406014105	ATP binding site [chemical binding]; other site
696406014106	Walker B motif; other site
696406014107	DNA binding loops [nucleotide binding]
696406014108	integrating conjugative element, PFGI_1 class, ParB family protein; Region: ICE_PFGI_1_parB; TIGR03764
696406014109	Protein of unknown function (DUF2786); Region: DUF2786; pfam10979
696406014110	Protein of unknown function (DUF2857); Region: DUF2857; pfam11198
696406014111	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
696406014112	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
696406014113	Domain of unknown function (DUF1845); Region: DUF1845; pfam08900
696406014114	DNA topoisomerase III; Provisional; Region: PRK07726
696406014115	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
696406014116	active site
696406014117	putative interdomain interaction site [polypeptide binding]; other site
696406014118	putative metal-binding site [ion binding]; other site
696406014119	putative nucleotide binding site [chemical binding]; other site
696406014120	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
696406014121	domain I; other site
696406014122	DNA binding groove [nucleotide binding]
696406014123	phosphate binding site [ion binding]; other site
696406014124	domain II; other site
696406014125	domain III; other site
696406014126	nucleotide binding site [chemical binding]; other site
696406014127	catalytic site [active]
696406014128	domain IV; other site
696406014129	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
696406014130	Protein of unknown function (DUF3577); Region: DUF3577; pfam12101
696406014131	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
696406014132	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
696406014133	dimer interface [polypeptide binding]; other site
696406014134	ssDNA binding site [nucleotide binding]; other site
696406014135	tetramer (dimer of dimers) interface [polypeptide binding]; other site
696406014136	hypothetical protein; Provisional; Region: PRK09956
696406014137	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
696406014138	conjugative transfer region protein, TIGR03748 family; Region: conj_PilL
696406014139	integrating conjugative element protein, PFL_4693 family; Region: conj_TIGR03759
696406014140	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
696406014141	N-acetyl-D-glucosamine binding site [chemical binding]; other site
696406014142	Protein of unknown function (DUF2859); Region: DUF2859; pfam11072
696406014143	conjugative coupling factor TraD, SXT/TOL subfamily; Region: SXT_TraD; TIGR03743
696406014144	conjugative coupling factor TraD, TOL family; Region: conj_TOL_TraD; TIGR03754
696406014145	integrating conjugative element membrane protein, PFL_4697 family; Region: conj_TIGR03747
696406014146	Plasmid protein of unknown function (Plasmid_RAQPRD); Region: Plasmid_RAQPRD; pfam09686
696406014147	Protein of unknown function (DUF3262); Region: DUF3262; cl13160
696406014148	integrating conjugative element membrane protein, PFL_4702 family; Region: conj_TIGR03745
696406014149	conjugative transfer region protein, TIGR03750 family; Region: conj_TIGR03750
696406014150	integrating conjugative element protein, PFL_4703 family; Region: conj_TIGR03746
696406014151	Protein of unknown function (DUF3438); Region: DUF3438; pfam11920
696406014152	integrating conjugative element protein, PFL_4705 family; Region: conj_TIGR03752
696406014153	conjugative transfer region lipoprotein, TIGR03751 family; Region: conj_TIGR03751
696406014154	conjugative transfer ATPase, PFL_4706 family; Region: traC_PFL_4706; TIGR03744
696406014155	F pilus assembly Type-IV secretion system for plasmid transfer; Region: TraC_F_IV; pfam11130
696406014156	Protein of unknown function (DUF1187); Region: DUF1187; cl11638
696406014157	integrating conjugative element protein, PFL_4709 family; Region: conj_TIGR03757
696406014158	integrating conjugative element protein, PFL_4710 family; Region: conj_TIGR03756
696406014159	integrating conjugative element protein, PFL_4711 family; Region: conj_TIGR03755
696406014160	TraG-like protein, N-terminal region; Region: TraG_N; pfam07916
696406014161	Phage integrase, N-terminal; Region: Integrase_l_N; pfam12834
696406014162	Integrase; Region: Integrase_1; pfam12835
696406014163	putative transposase OrfB; Reviewed; Region: PHA02517
696406014164	HTH-like domain; Region: HTH_21; pfam13276
696406014165	Integrase core domain; Region: rve; pfam00665
696406014166	Integrase core domain; Region: rve_3; pfam13683
696406014167	Transposase; Region: HTH_Tnp_1; cl17663
696406014168	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
696406014169	Antirestriction protein [DNA replication, recombination, and repair]; Region: COG4227
696406014170	Domain of unknown function (DUF1738); Region: DUF1738; pfam08401
696406014171	Protein of unknown function (DUF1281); Region: DUF1281; pfam06924
696406014172	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
696406014173	Nucleotidyltransferase (NT) domain of 2'5'-oligoadenylate (2-5A)synthetase (2-5OAS) and class I CCA-adding enzyme; Region: NT_2-5OAS_ClassI-CCAase; cd05400
696406014174	active site
696406014175	NTP binding site [chemical binding]; other site
696406014176	metal binding triad [ion binding]; metal-binding site
696406014177	Prokaryotic E2 family B; Region: Prok-E2_B; pfam14461
696406014178	Superfamily of activating enzymes (E1) of the ubiquitin-like proteins. This family includes classical ubiquitin-activating enzymes E1, ubiquitin-like (ubl) activating enzymes and other mechanistic homologes, like MoeB, Thif1 and others. The common...; Region: E1_enzyme_family; cd01483
696406014179	ATP binding site [chemical binding]; other site
696406014180	substrate interface [chemical binding]; other site
696406014181	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
696406014182	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
696406014183	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
696406014184	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
696406014185	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
696406014186	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
696406014187	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
696406014188	Family description; Region: UvrD_C_2; pfam13538
696406014189	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
696406014190	integrating conjugative element relaxase, PFL_4751 family; Region: ICE_TraI_Pfluor; TIGR03760
696406014191	Protein of unknown function (DUF1528); Region: DUF1528; pfam07515
696406014192	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
696406014193	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
696406014194	active site
696406014195	catalytic residues [active]
696406014196	DNA binding site [nucleotide binding]
696406014197	Int/Topo IB signature motif; other site
696406014198	putative transcriptional regulator; Provisional; Region: PRK11640
696406014199	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
696406014200	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
696406014201	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
696406014202	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
696406014203	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
696406014204	DsbD alpha interface [polypeptide binding]; other site
696406014205	catalytic residues [active]
696406014206	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
696406014207	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
696406014208	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
696406014209	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
696406014210	Aspartase; Region: Aspartase; cd01357
696406014211	active sites [active]
696406014212	tetramer interface [polypeptide binding]; other site
696406014213	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
696406014214	putative transporter; Provisional; Region: PRK11021
696406014215	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
696406014216	oligomerisation interface [polypeptide binding]; other site
696406014217	mobile loop; other site
696406014218	roof hairpin; other site
696406014219	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
696406014220	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
696406014221	ring oligomerisation interface [polypeptide binding]; other site
696406014222	ATP/Mg binding site [chemical binding]; other site
696406014223	stacking interactions; other site
696406014224	hinge regions; other site
696406014225	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
696406014226	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
696406014227	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
696406014228	FeS/SAM binding site; other site
696406014229	elongation factor P; Validated; Region: PRK00529
696406014230	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
696406014231	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
696406014232	RNA binding site [nucleotide binding]; other site
696406014233	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
696406014234	RNA binding site [nucleotide binding]; other site
696406014235	entericidin A; Provisional; Region: PRK09810
696406014236	entericidin B membrane lipoprotein; Provisional; Region: PRK10081
696406014237	multidrug efflux system protein; Provisional; Region: PRK11431
696406014238	Bacterial lipocalin [Cell envelope biogenesis, outer membrane]; Region: Blc; COG3040
696406014239	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
696406014240	beta-lactamase/D-alanine carboxypeptidase; Provisional; Region: ampC; PRK11289
696406014241	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
696406014242	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
696406014243	Iron-sulfur protein interface; other site
696406014244	proximal quinone binding site [chemical binding]; other site
696406014245	C-subunit interface; other site
696406014246	distal quinone binding site; other site
696406014247	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
696406014248	D-subunit interface [polypeptide binding]; other site
696406014249	Iron-sulfur protein interface; other site
696406014250	proximal quinone binding site [chemical binding]; other site
696406014251	distal quinone binding site [chemical binding]; other site
696406014252	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
696406014253	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
696406014254	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
696406014255	L-aspartate oxidase; Provisional; Region: PRK06175
696406014256	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
696406014257	poxB regulator PoxA; Provisional; Region: PRK09350
696406014258	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
696406014259	motif 1; other site
696406014260	dimer interface [polypeptide binding]; other site
696406014261	active site
696406014262	motif 2; other site
696406014263	motif 3; other site
696406014264	inner membrane transporter YjeM; Provisional; Region: PRK15238
696406014265	putative mechanosensitive channel protein; Provisional; Region: PRK10929
696406014266	linker histone 1 and histone 5 domains; the basic subunit of chromatin is the nucleosome, consisting of an octamer of core histones, two full turns of DNA, a linker histone (H1 or H5) and a variable length of linker DNA; H1/H5 are chromatin-associated...; Region: H15; cl00073
696406014267	DNA-binding site [nucleotide binding]; DNA binding site
696406014268	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
696406014269	Mechanosensitive ion channel; Region: MS_channel; pfam00924
696406014270	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
696406014271	GTPase RsgA; Reviewed; Region: PRK12288
696406014272	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
696406014273	RNA binding site [nucleotide binding]; other site
696406014274	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
696406014275	GTPase/Zn-binding domain interface [polypeptide binding]; other site
696406014276	GTP/Mg2+ binding site [chemical binding]; other site
696406014277	G4 box; other site
696406014278	G5 box; other site
696406014279	G1 box; other site
696406014280	Switch I region; other site
696406014281	G2 box; other site
696406014282	G3 box; other site
696406014283	Switch II region; other site
696406014284	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
696406014285	catalytic site [active]
696406014286	putative active site [active]
696406014287	putative substrate binding site [chemical binding]; other site
696406014288	dimer interface [polypeptide binding]; other site
696406014289	epoxyqueuosine reductase; Region: TIGR00276
696406014290	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
696406014291	putative carbohydrate kinase; Provisional; Region: PRK10565
696406014292	yjeF N-terminal region; Region: yjeF_nterm; TIGR00197
696406014293	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
696406014294	putative substrate binding site [chemical binding]; other site
696406014295	putative ATP binding site [chemical binding]; other site
696406014296	ADP-binding protein; Provisional; Region: PRK10646
696406014297	AMIN domain; Region: AMIN; pfam11741
696406014298	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
696406014299	active site
696406014300	metal binding site [ion binding]; metal-binding site
696406014301	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
696406014302	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
696406014303	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406014304	ATP binding site [chemical binding]; other site
696406014305	Mg2+ binding site [ion binding]; other site
696406014306	G-X-G motif; other site
696406014307	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
696406014308	ATP binding site [chemical binding]; other site
696406014309	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
696406014310	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
696406014311	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
696406014312	bacterial Hfq-like; Region: Hfq; cd01716
696406014313	hexamer interface [polypeptide binding]; other site
696406014314	Sm1 motif; other site
696406014315	RNA binding site [nucleotide binding]; other site
696406014316	Sm2 motif; other site
696406014317	GTPase HflX; Provisional; Region: PRK11058
696406014318	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
696406014319	HflX GTPase family; Region: HflX; cd01878
696406014320	G1 box; other site
696406014321	GTP/Mg2+ binding site [chemical binding]; other site
696406014322	Switch I region; other site
696406014323	G2 box; other site
696406014324	G3 box; other site
696406014325	Switch II region; other site
696406014326	G4 box; other site
696406014327	G5 box; other site
696406014328	FtsH protease regulator HflK; Provisional; Region: PRK10930
696406014329	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
696406014330	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
696406014331	FtsH protease regulator HflC; Provisional; Region: PRK11029
696406014332	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
696406014333	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3242
696406014334	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
696406014335	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
696406014336	GDP-binding site [chemical binding]; other site
696406014337	ACT binding site; other site
696406014338	IMP binding site; other site
696406014339	Predicted transcriptional regulator [Transcription]; Region: COG1959
696406014340	transcriptional repressor NsrR; Provisional; Region: PRK11014
696406014341	exoribonuclease R; Provisional; Region: PRK11642
696406014342	Ribonuclease R winged-helix domain; Region: HTH_12; pfam08461
696406014343	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
696406014344	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
696406014345	RNB domain; Region: RNB; pfam00773
696406014346	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
696406014347	RNA binding site [nucleotide binding]; other site
696406014348	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
696406014349	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
696406014350	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
696406014351	Transcriptional regulator [Transcription]; Region: IclR; COG1414
696406014352	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
696406014353	Bacterial transcriptional regulator; Region: IclR; pfam01614
696406014354	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
696406014355	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
696406014356	inhibitor site; inhibition site
696406014357	active site
696406014358	dimer interface [polypeptide binding]; other site
696406014359	catalytic residue [active]
696406014360	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
696406014361	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406014362	putative substrate translocation pore; other site
696406014363	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
696406014364	galactarate dehydratase; Region: galactar-dH20; TIGR03248
696406014365	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
696406014366	Uncharacterized protein conserved in bacteria (DUF2170); Region: DUF2170; cl01551
696406014367	Uncharacterized protein conserved in bacteria (DUF2170); Region: DUF2170; cl01551
696406014368	Protein of unknown function (DUF2491); Region: DUF2491; pfam10679
696406014369	Predicted membrane protein [Function unknown]; Region: COG3766
696406014370	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
696406014371	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
696406014372	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
696406014373	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
696406014374	Proteins involved in DNA damage response, similar to the AidB gene product; Region: AidB; cd01154
696406014375	FAD binding site [chemical binding]; other site
696406014376	substrate binding site [chemical binding]; other site
696406014377	catalytic residues [active]
696406014378	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
696406014379	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
696406014380	esterase; Provisional; Region: PRK10566
696406014381	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
696406014382	transcriptional repressor UlaR; Provisional; Region: PRK13509
696406014383	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
696406014384	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
696406014385	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
696406014386	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
696406014387	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
696406014388	PTS system ascorbate-specific transporter subunits IICB; Provisional; Region: PRK09548
696406014389	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
696406014390	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
696406014391	active site
696406014392	P-loop; other site
696406014393	phosphorylation site [posttranslational modification]
696406014394	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
696406014395	active site
696406014396	phosphorylation site [posttranslational modification]
696406014397	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
696406014398	active site
696406014399	dimer interface [polypeptide binding]; other site
696406014400	magnesium binding site [ion binding]; other site
696406014401	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
696406014402	phosphate binding site [ion binding]; other site
696406014403	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
696406014404	AP (apurinic/apyrimidinic) site pocket; other site
696406014405	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
696406014406	DNA interaction; other site
696406014407	Metal-binding active site; metal-binding site
696406014408	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
696406014409	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
696406014410	intersubunit interface [polypeptide binding]; other site
696406014411	active site
696406014412	Zn2+ binding site [ion binding]; other site
696406014413	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
696406014414	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
696406014415	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
696406014416	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
696406014417	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
696406014418	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
696406014419	Protein of unknown function (DUF2686); Region: DUF2686; pfam10887
696406014420	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
696406014421	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
696406014422	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
696406014423	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
696406014424	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
696406014425	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
696406014426	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
696406014427	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
696406014428	Hemerythrin-like domain; Region: Hr-like; cd12108
696406014429	Fe binding site [ion binding]; other site
696406014430	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
696406014431	EamA-like transporter family; Region: EamA; pfam00892
696406014432	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
696406014433	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
696406014434	NADP binding site [chemical binding]; other site
696406014435	Predicted transcriptional regulators [Transcription]; Region: COG1733
696406014436	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
696406014437	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
696406014438	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
696406014439	active site
696406014440	metal binding site [ion binding]; metal-binding site
696406014441	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
696406014442	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
696406014443	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
696406014444	active site
696406014445	Predicted transcriptional regulator [General function prediction only]; Region: COG3054
696406014446	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
696406014447	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
696406014448	Domain of unknown function DUF21; Region: DUF21; pfam01595
696406014449	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
696406014450	Transporter associated domain; Region: CorC_HlyC; smart01091
696406014451	methionine sulfoxide reductase A; Provisional; Region: PRK00058
696406014452	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
696406014453	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
696406014454	Surface antigen; Region: Bac_surface_Ag; pfam01103
696406014455	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
696406014456	Family of unknown function (DUF490); Region: DUF490; pfam04357
696406014457	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
696406014458	dimerization interface [polypeptide binding]; other site
696406014459	putative active site pocket [active]
696406014460	putative catalytic residue [active]
696406014461	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
696406014462	dimer interface [polypeptide binding]; other site
696406014463	substrate binding site [chemical binding]; other site
696406014464	metal binding sites [ion binding]; metal-binding site
696406014465	Periplasmic binding domain of ABC-type YtfQ-like transport systems; Region: PBP1_YtfQ_like; cd06309
696406014466	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
696406014467	putative ligand binding site [chemical binding]; other site
696406014468	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
696406014469	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
696406014470	Walker A/P-loop; other site
696406014471	ATP binding site [chemical binding]; other site
696406014472	Q-loop/lid; other site
696406014473	ABC transporter signature motif; other site
696406014474	Walker B; other site
696406014475	D-loop; other site
696406014476	H-loop/switch region; other site
696406014477	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
696406014478	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
696406014479	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
696406014480	TM-ABC transporter signature motif; other site
696406014481	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
696406014482	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
696406014483	TM-ABC transporter signature motif; other site
696406014484	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
696406014485	AMP binding site [chemical binding]; other site
696406014486	metal binding site [ion binding]; metal-binding site
696406014487	active site
696406014488	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
696406014489	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
696406014490	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
696406014491	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
696406014492	hypothetical protein; Provisional; Region: PRK05255
696406014493	peptidase PmbA; Provisional; Region: PRK11040
696406014494	cytochrome b562; Provisional; Region: PRK15058
696406014495	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
696406014496	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
696406014497	FeS/SAM binding site; other site
696406014498	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
696406014499	ATP cone domain; Region: ATP-cone; pfam03477
696406014500	Class III ribonucleotide reductase; Region: RNR_III; cd01675
696406014501	effector binding site; other site
696406014502	active site
696406014503	Zn binding site [ion binding]; other site
696406014504	glycine loop; other site
696406014505	trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933
696406014506	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
696406014507	Ca binding site [ion binding]; other site
696406014508	active site
696406014509	catalytic site [active]
696406014510	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
696406014511	PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional; Region: PRK11007
696406014512	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
696406014513	active site turn [active]
696406014514	phosphorylation site [posttranslational modification]
696406014515	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
696406014516	trehalose repressor; Provisional; Region: treR; PRK09492
696406014517	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
696406014518	DNA binding site [nucleotide binding]
696406014519	domain linker motif; other site
696406014520	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
696406014521	dimerization interface [polypeptide binding]; other site
696406014522	ligand binding site [chemical binding]; other site
696406014523	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
696406014524	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
696406014525	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
696406014526	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
696406014527	Soluble P-type ATPase [General function prediction only]; Region: COG4087
696406014528	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
696406014529	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
696406014530	homotrimer interaction site [polypeptide binding]; other site
696406014531	putative active site [active]
696406014532	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
696406014533	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
696406014534	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
696406014535	aspartate carbamoyltransferase; Region: asp_carb_tr; TIGR00670
696406014536	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
696406014537	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
696406014538	YjgH belongs to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgH_like; cd02198
696406014539	homotrimer interaction site [polypeptide binding]; other site
696406014540	putative active site [active]
696406014541	oxidoreductase; Provisional; Region: PRK12742
696406014542	classical (c) SDRs; Region: SDR_c; cd05233
696406014543	NAD(P) binding site [chemical binding]; other site
696406014544	active site
696406014545	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
696406014546	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
696406014547	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
696406014548	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
696406014549	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3076
696406014550	RNase E inhibitor protein; Provisional; Region: PRK11191
696406014551	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
696406014552	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
696406014553	Coenzyme A binding pocket [chemical binding]; other site
696406014554	Bacterial protein of unknown function (DUF898); Region: DUF898; cl01738
696406014555	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
696406014556	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
696406014557	HIGH motif; other site
696406014558	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
696406014559	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
696406014560	active site
696406014561	KMSKS motif; other site
696406014562	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
696406014563	tRNA binding surface [nucleotide binding]; other site
696406014564	anticodon binding site; other site
696406014565	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
696406014566	DNA polymerase III subunit chi; Validated; Region: PRK05728
696406014567	multifunctional aminopeptidase A; Provisional; Region: PRK00913
696406014568	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
696406014569	interface (dimer of trimers) [polypeptide binding]; other site
696406014570	Substrate-binding/catalytic site; other site
696406014571	Zn-binding sites [ion binding]; other site
696406014572	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
696406014573	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
696406014574	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
696406014575	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
696406014576	Bacterial protein of unknown function (DUF853); Region: DUF853; pfam05872
696406014577	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
696406014578	Walker A motif; other site
696406014579	ATP binding site [chemical binding]; other site
696406014580	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
696406014581	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
696406014582	putative NAD(P) binding site [chemical binding]; other site
696406014583	putative substrate binding site [chemical binding]; other site
696406014584	catalytic Zn binding site [ion binding]; other site
696406014585	structural Zn binding site [ion binding]; other site
696406014586	dimer interface [polypeptide binding]; other site
696406014587	potential protein location (hypothetical protein UMNK88_5211 [Escherichia coli UMNK88]) that overlaps RNA (tRNA-L)
696406014588	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
696406014589	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
696406014590	Helix-turn-helix domain; Region: HTH_38; pfam13936
696406014591	Integrase core domain; Region: rve; pfam00665
696406014592	putative transposase OrfB; Reviewed; Region: PHA02517
696406014593	HTH-like domain; Region: HTH_21; pfam13276
696406014594	Integrase core domain; Region: rve; pfam00665
696406014595	Integrase core domain; Region: rve_3; pfam13683
696406014596	BCCT family transporter; Region: BCCT; cl00569
696406014597	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
696406014598	Integrase core domain; Region: rve; pfam00665
696406014599	Integrase core domain; Region: rve_3; pfam13683
696406014600	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
696406014601	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
696406014602	putative acyl-acceptor binding pocket; other site
696406014603	Protein of unknown function (DUF535); Region: DUF535; pfam04393
696406014604	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
696406014605	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
696406014606	Putative catalytic NodB homology domain of a hypothetical protein Ecf1 from Escherichia coli and similar proteins; Region: CE4_Ecf1_like_5s; cd10969
696406014607	putative active site [active]
696406014608	putative metal binding site [ion binding]; other site
696406014609	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
696406014610	Transposase; Region: HTH_Tnp_1; cl17663
696406014611	HTH-like domain; Region: HTH_21; pfam13276
696406014612	Integrase core domain; Region: rve; pfam00665
696406014613	iron-dicitrate transporter ATP-binding subunit; Provisional; Region: fecE; PRK11231
696406014614	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
696406014615	ABC transporter signature motif; other site
696406014616	Walker B; other site
696406014617	D-loop; other site
696406014618	H-loop/switch region; other site
696406014619	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
696406014620	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
696406014621	ABC-ATPase subunit  interface; other site
696406014622	dimer interface [polypeptide binding]; other site
696406014623	putative PBP binding regions; other site
696406014624	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
696406014625	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
696406014626	dimer interface [polypeptide binding]; other site
696406014627	ABC-ATPase subunit  interface; other site
696406014628	putative PBP binding regions; other site
696406014629	iron-dicitrate transporter substrate-binding subunit; Provisional; Region: fecB; PRK11411
696406014630	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
696406014631	siderophore binding site; other site
696406014632	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
696406014633	Secretin and TonB N terminus short domain; Region: STN; smart00965
696406014634	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
696406014635	N-terminal plug; other site
696406014636	ligand-binding site [chemical binding]; other site
696406014637	fec operon regulator FecR; Reviewed; Region: PRK09774
696406014638	FecR protein; Region: FecR; pfam04773
696406014639	RNA polymerase sigma factor FecI; Provisional; Region: PRK09651
696406014640	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
696406014641	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
696406014642	DNA binding residues [nucleotide binding]
696406014643	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
696406014644	Esterase-like activity of phytase; Region: Phytase-like; pfam13449
696406014645	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
696406014646	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
696406014647	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
696406014648	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
696406014649	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
696406014650	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
696406014651	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
696406014652	Transposase domain (DUF772); Region: DUF772; pfam05598
696406014653	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
696406014654	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
696406014655	fructuronate transporter; Provisional; Region: PRK10034
696406014656	gluconate transporter; Region: gntP; TIGR00791
696406014657	mannonate dehydratase; Region: uxuA; TIGR00695
696406014658	mannonate dehydratase; Provisional; Region: PRK03906
696406014659	D-mannonate oxidoreductase; Provisional; Region: PRK15037
696406014660	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
696406014661	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
696406014662	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
696406014663	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
696406014664	DNA-binding site [nucleotide binding]; DNA binding site
696406014665	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
696406014666	Protein of unknown function (DUF2686); Region: DUF2686; pfam10887
696406014667	DNA replication/recombination/repair protein; Provisional; Region: iraD; PRK14128
696406014668	cell density-dependent motility repressor; Provisional; Region: PRK10082
696406014669	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406014670	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
696406014671	Isoaspartyl dipeptidase hydrolyzes the beta-L-isoaspartyl linkages in dipeptides, as part of the degradative pathway to eliminate proteins with beta-L-isoaspartyl peptide bonds, bonds whereby the beta-group of an aspartate forms the peptide link with the...; Region: Isoaspartyl-dipeptidase; cd01308
696406014672	isoaspartyl dipeptidase IadA; Region: isoAsp_dipep; TIGR01975
696406014673	dimer interface [polypeptide binding]; other site
696406014674	active site
696406014675	hypothetical protein; Provisional; Region: PRK10519
696406014676	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
696406014677	Nucleoside recognition; Region: Gate; pfam07670
696406014678	RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; Region: KptA; COG1859
696406014679	RNA 2'-phosphotransferase; Reviewed; Region: PRK00819
696406014680	Major Facilitator Superfamily; Region: MFS_1; pfam07690
696406014681	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406014682	putative substrate translocation pore; other site
696406014683	SdiA-regulated; Region: SdiA-regulated; pfam06977
696406014684	SdiA-regulated; Region: SdiA-regulated; cd09971
696406014685	putative active site [active]
696406014686	Protein of unknown function (DUF3343); Region: DUF3343; pfam11823
696406014687	Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism]; Region: COG1924
696406014688	CoA-substrate-specific enzyme activase, putative; Region: CoA_E_activ; TIGR00241
696406014689	Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB [Amino acid transport and metabolism]; Region: HgdB; COG1775
696406014690	benzoyl-CoA reductase, subunit C; Region: benz_CoA_red_C; TIGR02263
696406014691	Predicted membrane protein [Function unknown]; Region: COG2733
696406014692	multidrug efflux system protein MdtM; Provisional; Region: PRK15403
696406014693	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406014694	putative substrate translocation pore; other site
696406014695	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
696406014696	IS1 transposase; Region: DDE_Tnp_IS1; cl00721
696406014697	Protein of unknown function (DUF497); Region: DUF497; cl01108
696406014698	Domain of unknown function (DUF4415); Region: DUF4415; cl01401
696406014699	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
696406014700	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
696406014701	P-loop, Walker A motif; other site
696406014702	Base recognition motif; other site
696406014703	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
696406014704	Uncharacterized small protein [Function unknown]; Region: COG2879
696406014705	carbon starvation protein A; Provisional; Region: PRK15015
696406014706	Carbon starvation protein CstA; Region: CstA; pfam02554
696406014707	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
696406014708	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
696406014709	dimer interface [polypeptide binding]; other site
696406014710	ligand binding site [chemical binding]; other site
696406014711	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
696406014712	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
696406014713	dimerization interface [polypeptide binding]; other site
696406014714	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
696406014715	dimer interface [polypeptide binding]; other site
696406014716	putative CheW interface [polypeptide binding]; other site
696406014717	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406014718	D-galactonate transporter; Region: 2A0114; TIGR00893
696406014719	putative substrate translocation pore; other site
696406014720	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
696406014721	DNA-binding site [nucleotide binding]; DNA binding site
696406014722	Transcriptional regulators [Transcription]; Region: GntR; COG1802
696406014723	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
696406014724	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
696406014725	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
696406014726	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
696406014727	putative NAD(P) binding site [chemical binding]; other site
696406014728	catalytic Zn binding site [ion binding]; other site
696406014729	structural Zn binding site [ion binding]; other site
696406014730	phosphoglycerol transferase I; Provisional; Region: PRK03776
696406014731	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
696406014732	hypothetical protein; Provisional; Region: PRK11667
696406014733	DNA replication protein DnaC; Validated; Region: PRK07952
696406014734	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406014735	Walker A motif; other site
696406014736	ATP binding site [chemical binding]; other site
696406014737	Walker B motif; other site
696406014738	primosomal protein DnaI; Provisional; Region: PRK02854
696406014739	hypothetical protein; Provisional; Region: PRK09917
696406014740	Uncharacterized conserved protein [Function unknown]; Region: COG2966
696406014741	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
696406014742	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
696406014743	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
696406014744	DNA binding residues [nucleotide binding]
696406014745	dimerization interface [polypeptide binding]; other site
696406014746	DNA-binding transcriptional activator BglJ; Provisional; Region: PRK11475
696406014747	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
696406014748	DNA binding residues [nucleotide binding]
696406014749	dimerization interface [polypeptide binding]; other site
696406014750	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
696406014751	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
696406014752	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
696406014753	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
696406014754	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
696406014755	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
696406014756	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
696406014757	S-adenosylmethionine binding site [chemical binding]; other site
696406014758	DNA polymerase III subunit psi; Validated; Region: PRK06856
696406014759	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
696406014760	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
696406014761	Coenzyme A binding pocket [chemical binding]; other site
696406014762	dUMP phosphatase; Provisional; Region: PRK09449
696406014763	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696406014764	motif II; other site
696406014765	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
696406014766	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
696406014767	G1 box; other site
696406014768	putative GEF interaction site [polypeptide binding]; other site
696406014769	GTP/Mg2+ binding site [chemical binding]; other site
696406014770	Switch I region; other site
696406014771	G2 box; other site
696406014772	G3 box; other site
696406014773	Switch II region; other site
696406014774	G4 box; other site
696406014775	G5 box; other site
696406014776	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
696406014777	periplasmic protein; Provisional; Region: PRK10568
696406014778	BON domain; Region: BON; pfam04972
696406014779	BON domain; Region: BON; pfam04972
696406014780	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
696406014781	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
696406014782	active site
696406014783	nucleophile elbow; other site
696406014784	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
696406014785	active site
696406014786	4Fe-4S dicluster domain; Region: Fer4_9; pfam13187
696406014787	Radical SAM superfamily; Region: Radical_SAM; pfam04055
696406014788	hypothetical protein; Provisional; Region: PRK10977
696406014789	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
696406014790	intersubunit interface [polypeptide binding]; other site
696406014791	active site
696406014792	catalytic residue [active]
696406014793	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
696406014794	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
696406014795	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
696406014796	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
696406014797	phosphopentomutase; Provisional; Region: PRK05362
696406014798	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
696406014799	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
696406014800	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
696406014801	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
696406014802	non-specific DNA binding site [nucleotide binding]; other site
696406014803	salt bridge; other site
696406014804	sequence-specific DNA binding site [nucleotide binding]; other site
696406014805	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
696406014806	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
696406014807	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
696406014808	hypothetical protein; Provisional; Region: PRK11246
696406014809	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
696406014810	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
696406014811	motif II; other site
696406014812	DNA repair protein RadA; Region: sms; TIGR00416
696406014813	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
696406014814	Walker A motif/ATP binding site; other site
696406014815	ATP binding site [chemical binding]; other site
696406014816	Walker B motif; other site
696406014817	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
696406014818	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
696406014819	non-specific DNA binding site [nucleotide binding]; other site
696406014820	salt bridge; other site
696406014821	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
696406014822	sequence-specific DNA binding site [nucleotide binding]; other site
696406014823	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
696406014824	active site
696406014825	(T/H)XGH motif; other site
696406014826	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
696406014827	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
696406014828	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
696406014829	Walker A/P-loop; other site
696406014830	ATP binding site [chemical binding]; other site
696406014831	Q-loop/lid; other site
696406014832	ABC transporter signature motif; other site
696406014833	Walker B; other site
696406014834	D-loop; other site
696406014835	H-loop/switch region; other site
696406014836	ABC transporter; Region: ABC_tran_2; pfam12848
696406014837	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
696406014838	lytic murein transglycosylase; Provisional; Region: PRK11619
696406014839	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
696406014840	N-acetyl-D-glucosamine binding site [chemical binding]; other site
696406014841	catalytic residue [active]
696406014842	Trp operon repressor; Provisional; Region: PRK01381
696406014843	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
696406014844	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
696406014845	catalytic core [active]
696406014846	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
696406014847	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
696406014848	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
696406014849	hypothetical protein; Provisional; Region: PRK10756
696406014850	CreA protein; Region: CreA; pfam05981
696406014851	DNA-binding response regulator CreB; Provisional; Region: PRK11083
696406014852	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406014853	active site
696406014854	phosphorylation site [posttranslational modification]
696406014855	intermolecular recognition site; other site
696406014856	dimerization interface [polypeptide binding]; other site
696406014857	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
696406014858	DNA binding site [nucleotide binding]
696406014859	sensory histidine kinase CreC; Provisional; Region: PRK11100
696406014860	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
696406014861	dimerization interface [polypeptide binding]; other site
696406014862	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
696406014863	dimer interface [polypeptide binding]; other site
696406014864	phosphorylation site [posttranslational modification]
696406014865	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
696406014866	ATP binding site [chemical binding]; other site
696406014867	Mg2+ binding site [ion binding]; other site
696406014868	G-X-G motif; other site
696406014869	Inner membrane protein involved in colicin E2 resistance [Defense mechanisms]; Region: CreD; COG4452
696406014870	two-component response regulator; Provisional; Region: PRK11173
696406014871	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
696406014872	active site
696406014873	phosphorylation site [posttranslational modification]
696406014874	intermolecular recognition site; other site
696406014875	dimerization interface [polypeptide binding]; other site
696406014876	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
696406014877	DNA binding site [nucleotide binding]
696406014878	putative RNA methyltransferase; Provisional; Region: PRK10433
696406014879	RNA methyltransferase, TrmH family, group 1; Region: rRNA_methyl_1; TIGR00050
696406014880	IncFII RepA protein family; Region: IncFII_repA; cl11495
696406014881	FinO bacterial conjugation repressor domain;  the basic protein FinO is part of the the two component FinOP system which is responsible for repressing bacterial conjugation; the FinOP system represses the transfer (tra) operon of the F-plasmid which...; Region: FinO_conjug_rep; cd00236
696406014882	putative kissing complex interaction region; other site
696406014883	putative RNA binding sites [nucleotide binding]; other site
696406014884	Colicin Ia; Region: Colicin_Ia; pfam11504
696406014885	Colicin pore forming domain; Region: Colicin; pfam01024
696406014886	Colicin E1 (microcin) immunity protein; Region: Microcin; pfam03526
696406014887	Phage integrase family; Region: Phage_integrase; pfam00589
696406014888	active site
696406014889	DNA binding site [nucleotide binding]
696406014890	Int/Topo IB signature motif; other site
696406014891	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
696406014892	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
696406014893	P-loop; other site
696406014894	Magnesium ion binding site [ion binding]; other site
696406014895	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
696406014896	Mg binding site [ion binding]; other site
696406014897	nucleotide binding site [chemical binding]; other site
696406014898	putative protofilament interface [polypeptide binding]; other site
696406014899	Plasmid stability protein; Region: Plasmid_stab_B; pfam10784
696406014900	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
696406014901	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
696406014902	active site
696406014903	DNA binding site [nucleotide binding]
696406014904	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
696406014905	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
696406014906	Catalytic site [active]
696406014907	DinI-like family; Region: DinI; pfam06183
696406014908	Protein of unknown function (DUF1281); Region: DUF1281; pfam06924
696406014909	putative methylase; Provisional; Region: PRK13699
696406014910	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
696406014911	Protein of unknown function (DUF1380); Region: DUF1380; pfam07128
696406014912	Protein of unknown function (DUF1472); Region: DUF1472; pfam07339
696406014913	Antirestriction protein; Region: Antirestrict; pfam03230
696406014914	Protein of unknown function (DUF1380); Region: DUF1380; pfam07128
696406014915	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
696406014916	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
696406014917	dimer interface [polypeptide binding]; other site
696406014918	ssDNA binding site [nucleotide binding]; other site
696406014919	tetramer (dimer of dimers) interface [polypeptide binding]; other site
696406014920	ParB-like nuclease domain; Region: ParBc; pfam02195
696406014921	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
696406014922	plasmid SOS inhibition protein B; Provisional; Region: psiB; PRK13701
696406014923	PsiA protein; Region: PsiA; pfam06952
696406014924	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
696406014925	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
696406014926	Probable transposase; Region: OrfB_IS605; pfam01385
696406014927	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
696406014928	Antirestriction protein (ArdA); Region: ArdA; pfam07275
696406014929	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
696406014930	Methyltransferase domain; Region: Methyltransf_27; pfam13708
696406014931	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
696406014932	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
696406014933	dimerization domain [polypeptide binding]; other site
696406014934	dimer interface [polypeptide binding]; other site
696406014935	catalytic residues [active]
696406014936	Transposase; Region: HTH_Tnp_1; pfam01527
696406014937	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
696406014938	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
696406014939	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
696406014940	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
696406014941	Transposase C of IS166 homeodomain; Region: LZ_Tnp_IS66; pfam13007
696406014942	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
696406014943	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
696406014944	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
696406014945	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
696406014946	conjugal transfer/type IV secretion protein DotA/TraY; Region: DotA_TraY; TIGR04346
696406014947	indole-3-acetamide amidohydrolase; Region: PLN02722
696406014948	AAA-like domain; Region: AAA_10; pfam12846
696406014949	Protein of unknown function (DUF3625); Region: DUF3625; pfam12293
696406014950	Macrophage killing protein with similarity to conjugation protein; Region: IcmL; pfam11393
696406014951	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4643
696406014952	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
696406014953	active site
696406014954	metal binding site [ion binding]; metal-binding site
696406014955	interdomain interaction site; other site
696406014956	Catalytic domain of EDTA-resistant nuclease Nuc from Salmonella typhimurium and similar proteins; Region: PLDc_Nuc; cd09170
696406014957	PLD-like domain; Region: PLDc_2; pfam13091
696406014958	putative active site [active]
696406014959	catalytic site [active]
696406014960	plasmid transfer ATPase TraJ; Region: plasmid_TraJ; TIGR02525
696406014961	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
696406014962	Walker A motif; other site
696406014963	ATP binding site [chemical binding]; other site
696406014964	Walker B motif; other site
696406014965	putative transposase OrfB; Reviewed; Region: PHA02517
696406014966	HTH-like domain; Region: HTH_21; pfam13276
696406014967	Integrase core domain; Region: rve; pfam00665
696406014968	Integrase core domain; Region: rve_3; pfam13683
696406014969	Transposase; Region: HTH_Tnp_1; cl17663
696406014970	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
696406014971	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
696406014972	catalytic core [active]
696406014973	F plasmid transfer operon, TraF, protein; Region: TraF_2; pfam13729
696406014974	Rci recombinase, C-terminal catalytic domain.  Rci enzymes are found in IncI1 incompatibility group plasmids such as R64.  These recombinases belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain...; Region: INT_Rci; cd00796
696406014975	catalytic residues [active]
696406014976	Int/Topo IB signature motif; other site
696406014977	Bacterial shufflon protein, N-terminal constant region; Region: Shufflon_N; pfam04917
696406014978	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
696406014979	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
696406014980	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
696406014981	N-acetyl-D-glucosamine binding site [chemical binding]; other site
696406014982	catalytic residue [active]
696406014983	PilS N terminal; Region: PilS; pfam08805
696406014984	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
696406014985	Type II/IV secretion system protein; Region: T2SE; pfam00437
696406014986	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
696406014987	Walker A motif; other site
696406014988	ATP binding site [chemical binding]; other site
696406014989	Walker B motif; other site
696406014990	type IV pilus biogenesis protein PilP; Region: pilP_fam; TIGR03021
696406014991	Pilin accessory protein (PilO); Region: PAP_PilO; pfam06864
696406014992	type IVB pilus formation outer membrane protein, R64 PilN family; Region: pilus_B_mal_scr; TIGR02520
696406014993	Secretin N-terminal domain; Region: Secretin_N_2; pfam07655
696406014994	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
696406014995	PilM; Region: PilM; pfam07419
696406014996	Toxin co-regulated pilus biosynthesis protein Q; Region: TcpQ; pfam10671
696406014997	Plasmid conjugative transfer protein PilI; Region: PilI; pfam10623
696406014998	Protein of unknown function (DUF2913); Region: DUF2913; pfam11140
696406014999	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315
696406015000	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436
696406015001	IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717
696406015002	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cl17257
696406015003	DNA binding residues [nucleotide binding]
696406015004	Protein of unknown function (DUF1472); Region: DUF1472; pfam07339
696406015005	Antirestriction protein (ArdA); Region: ArdA; pfam07275
696406015006	Methyltransferase domain; Region: Methyltransf_27; pfam13708
696406015007	conjugal transfer relaxosome component TraJ; Provisional; Region: PRK13877
696406015008	Relaxase/Mobilisation nuclease domain; Region: Relaxase; pfam03432
696406015009	conjugal transfer relaxase TraI; Provisional; Region: PRK13878
696406015010	Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]; Region: VapC; COG1487
696406015011	putative active site [active]
696406015012	potential frameshift: common BLAST hit: gi|300724497|ref|YP_003713818.1| invasin
696406015013	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
696406015014	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
696406015015	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
696406015016	Bacterial Ig-like domain (group 1); Region: Big_1; cl17740
696406015017	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
696406015018	Catalytic domain of EDTA-resistant nuclease Nuc from Salmonella typhimurium and similar proteins; Region: PLDc_Nuc; cd09170
696406015019	PLD-like domain; Region: PLDc_2; pfam13091
696406015020	putative active site [active]
696406015021	catalytic site [active]
696406015022	TraM recognition site of TraD and TraG; Region: TraG-D_C; cl17375
696406015023	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
696406015024	conjugal transfer/type IV secretion protein DotA/TraY; Region: DotA_TraY; TIGR04346
696406015025	AAA-like domain; Region: AAA_10; pfam12846
696406015026	Protein of unknown function (DUF3625); Region: DUF3625; pfam12293
696406015027	Macrophage killing protein with similarity to conjugation protein; Region: IcmL; pfam11393
696406015028	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4643
696406015029	TOPRIM_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_primases; cd01029
696406015030	active site
696406015031	metal binding site [ion binding]; metal-binding site
696406015032	interdomain interaction site; other site
696406015033	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
696406015034	Walker A motif; other site
696406015035	ATP binding site [chemical binding]; other site
696406015036	Walker B motif; other site
696406015037	Protein of unknown function (DUF2913); Region: DUF2913; pfam11140
696406015038	N-Utilization Substance G (NusG) N-terminal (NGN) domain Superfamily; Region: NGN; cl02766
696406015039	RelB antitoxin; Region: RelB; cl01171
696406015040	RTX toxin acyltransferase family; Region: HlyC; pfam02794
696406015041	RTX N-terminal domain; Region: RTX; pfam02382
696406015042	RTX C-terminal domain; Region: RTX_C; pfam08339
696406015043	A sub-family of peptidase C39 which contains Cyclolysin and Hemolysin processing peptidases.  Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine...; Region: Peptidase_C39_likeA; cd02417
696406015044	type I secretion system ABC transporter, HlyB family; Region: type_I_sec_HlyB; TIGR01846
696406015045	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
696406015046	ATP-binding cassette domain of hemolysin B, subfamily C; Region: ABCC_Hemolysin; cd03252
696406015047	Walker A/P-loop; other site
696406015048	ATP binding site [chemical binding]; other site
696406015049	Q-loop/lid; other site
696406015050	ABC transporter signature motif; other site
696406015051	Walker B; other site
696406015052	D-loop; other site
696406015053	H-loop/switch region; other site
696406015054	type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843
696406015055	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
696406015056	HlyD family secretion protein; Region: HlyD_3; pfam13437
696406015057	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
696406015058	Protein of unknown function (DUF433); Region: DUF433; cl01030
696406015059	MULE transposase domain; Region: MULE; pfam10551
696406015060	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
696406015061	Mg binding site [ion binding]; other site
696406015062	nucleotide binding site [chemical binding]; other site
696406015063	putative protofilament interface [polypeptide binding]; other site
696406015064	Plasmid stability protein; Region: Plasmid_stab_B; pfam10784
696406015065	putative methylase; Provisional; Region: PRK13699
696406015066	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
696406015067	Protein of unknown function (DUF1380); Region: DUF1380; pfam07128
696406015068	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
696406015069	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
696406015070	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
696406015071	Ligand Binding Site [chemical binding]; other site
696406015072	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
696406015073	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
696406015074	tandem repeat interface [polypeptide binding]; other site
696406015075	oligomer interface [polypeptide binding]; other site
696406015076	active site residues [active]
696406015077	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
696406015078	DsbA family; consists of DsbA and DsbA-like proteins, including DsbC, DsbG, glutathione (GSH) S-transferase kappa (GSTK), 2-hydroxychromene-2-carboxylate (HCCA) isomerase, an oxidoreductase (FrnE) presumed to be involved in frenolicin biosynthesis, a...; Region: DsbA_family; cd02972
696406015079	catalytic residues [active]
696406015080	Staphylococcal nuclease homologues; Region: SNc; smart00318
696406015081	Staphylococcal nuclease homologues. SNase homologues are found in bacteria, archaea, and eukaryotes. They contain no disufide bonds; Region: SNc; cd00175
696406015082	Catalytic site; other site
696406015083	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
696406015084	IHF dimer interface [polypeptide binding]; other site
696406015085	IHF - DNA interface [nucleotide binding]; other site
696406015086	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
696406015087	non-specific DNA binding site [nucleotide binding]; other site
696406015088	salt bridge; other site
696406015089	sequence-specific DNA binding site [nucleotide binding]; other site
696406015090	Phage derived protein Gp49-like (DUF891); Region: Gp49; cl01470
696406015091	Protein of unknown function (DUF1643); Region: DUF1643; pfam07799
696406015092	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316
696406015093	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
696406015094	Integrase core domain; Region: rve; pfam00665
696406015095	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316
696406015096	Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050
696406015097	Integrase core domain; Region: rve; pfam00665
696406015098	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
696406015099	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788
696406015100	catalytic residues [active]
696406015101	catalytic nucleophile [active]
696406015102	Transposase zinc-binding domain; Region: Zn_Tnp_IS91; pfam14319
696406015103	Putative transposase; Region: Y2_Tnp; pfam04986
696406015104	Protein of unknown function (DUF3363); Region: DUF3363; pfam11843
696406015105	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
696406015106	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406015107	putative substrate translocation pore; other site
696406015108	Transcriptional regulator [Transcription]; Region: LysR; COG0583
696406015109	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
696406015110	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406015111	Major Facilitator Superfamily; Region: MFS_1; pfam07690
696406015112	putative substrate translocation pore; other site
696406015113	tetracycline repressor protein TetR; Provisional; Region: PRK13756
696406015114	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
696406015115	Tetracyclin repressor, C-terminal all-alpha domain; Region: TetR_C; pfam02909
696406015116	Aminoglycoside/hydroxyurea antibiotic resistance kinase; Region: APH_6_hur; pfam04655
696406015117	Aminoglycoside 3'-phosphotransferase (APH). The APH subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin...; Region: APH; cd05150
696406015118	Phosphotransferase enzyme family; Region: APH; pfam01636
696406015119	active site
696406015120	ATP binding site [chemical binding]; other site
696406015121	antibiotic binding site [chemical binding]; other site
696406015122	dihydropteroate synthase; Region: DHPS; TIGR01496
696406015123	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
696406015124	substrate binding pocket [chemical binding]; other site
696406015125	dimer interface [polypeptide binding]; other site
696406015126	inhibitor binding site; inhibition site
696406015127	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
696406015128	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
696406015129	P-loop; other site
696406015130	Magnesium ion binding site [ion binding]; other site
696406015131	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
696406015132	Magnesium ion binding site [ion binding]; other site
696406015133	ParB-like nuclease domain; Region: ParB; smart00470
696406015134	KorB domain; Region: KorB; pfam08535
696406015135	Uncharacterized protein conserved in bacteria (DUF2131); Region: DUF2131; cl11547
696406015136	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
696406015137	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
696406015138	DNA topoisomerase III; Provisional; Region: PRK07726
696406015139	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
696406015140	active site
696406015141	putative interdomain interaction site [polypeptide binding]; other site
696406015142	putative metal-binding site [ion binding]; other site
696406015143	putative nucleotide binding site [chemical binding]; other site
696406015144	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
696406015145	domain I; other site
696406015146	DNA binding groove [nucleotide binding]
696406015147	phosphate binding site [ion binding]; other site
696406015148	domain II; other site
696406015149	domain III; other site
696406015150	nucleotide binding site [chemical binding]; other site
696406015151	catalytic site [active]
696406015152	domain IV; other site
696406015153	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
696406015154	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
696406015155	Putative helicase; Region: TraI_2; pfam07514
696406015156	integrating conjugative element relaxase, PFL_4751 family; Region: ICE_TraI_Pfluor; TIGR03760
696406015157	conjugative coupling factor TraD, SXT/TOL subfamily; Region: SXT_TraD; TIGR03743
696406015158	TraM recognition site of TraD and TraG; Region: TraG-D_C; cl17375
696406015159	cellulose synthase-like protein; Region: PLN02248
696406015160	Domain of unknown function (DUF4400); Region: DUF4400; pfam14348
696406015161	TraL protein; Region: TraL; cl06278
696406015162	TraE protein; Region: TraE; cl05060
696406015163	conjugal transfer protein TraK; Provisional; Region: PRK13736; cl05878
696406015164	Bacterial conjugation TrbI-like protein; Region: TrbI; pfam03743
696406015165	type IV conjugative transfer system lipoprotein TraV; Region: TraV; TIGR02747
696406015166	Type IV conjugative transfer system lipoprotein (TraV); Region: TraV; pfam09676
696406015167	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
696406015168	beta-lactamase/D-alanine carboxypeptidase; Provisional; Region: ampC; PRK11289
696406015169	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
696406015170	outer membrane lipoprotein Blc; Provisional; Region: PRK10477
696406015171	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
696406015172	multidrug efflux system protein; Provisional; Region: PRK11431
696406015173	Domain of unknown function (DUF4165); Region: DUF4165; pfam13752
696406015174	Bacterial Ig-like domain (group 3); Region: Big_3_2; pfam12245
696406015175	Bacterial Ig-like domain (group 3); Region: Big_3_3; pfam13750
696406015176	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
696406015177	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
696406015178	dimerization domain [polypeptide binding]; other site
696406015179	dimer interface [polypeptide binding]; other site
696406015180	catalytic residues [active]
696406015181	F pilus assembly Type-IV secretion system for plasmid transfer; Region: TraC_F_IV; pfam11130
696406015182	type-IV secretion system protein TraC; Region: TraC-F-type; TIGR02746
696406015183	Domain of unknown function DUF87; Region: DUF87; pfam01935
696406015184	TraM recognition site of TraD and TraG; Region: TraG-D_C; cl17375
696406015185	conjugative transfer signal peptidase TraF; Region: TraF_Ti; TIGR02771
696406015186	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
696406015187	Type-F conjugative transfer system pilin assembly protein; Region: TrbC_Ftype; pfam09673
696406015188	Sex factor F TraW protein N terminal; Region: TraW_N; cl10149
696406015189	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
696406015190	TraU protein; Region: TraU; pfam06834
696406015191	conjugal transfer mating pair stabilization protein TraN; Provisional; Region: PRK14876
696406015192	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406015193	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
696406015194	Walker A motif; other site
696406015195	ATP binding site [chemical binding]; other site
696406015196	Walker B motif; other site
696406015197	CbbQ/NirQ/NorQ C-terminal; Region: CbbQ_C; pfam08406
696406015198	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
696406015199	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
696406015200	dimer interface [polypeptide binding]; other site
696406015201	ssDNA binding site [nucleotide binding]; other site
696406015202	tetramer (dimer of dimers) interface [polypeptide binding]; other site
696406015203	RecT family; Region: RecT; cl04285
696406015204	YqaJ-like viral recombinase domain; Region: YqaJ; cl09232
696406015205	Protein of unknown function (DUF3150); Region: DUF3150; pfam11348
696406015206	Cobalamin biosynthesis protein CobT; Region: CobT; pfam06213
696406015207	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
696406015208	metal ion-dependent adhesion site (MIDAS); other site
696406015209	Endoglucanase [Carbohydrate transport and metabolism]; Region: BglC; COG2730
696406015210	Dam-replacing family; Region: DRP; pfam06044
696406015211	Protein of unknown function (DUF475); Region: DUF475; cl17481
696406015212	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
696406015213	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
696406015214	cofactor binding site; other site
696406015215	DNA binding site [nucleotide binding]
696406015216	substrate interaction site [chemical binding]; other site
696406015217	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
696406015218	Ligand Binding Site [chemical binding]; other site
696406015219	HD domain; Region: HD_3; cl17350
696406015220	Zinc-binding domain of primase-helicase; Region: Prim_Zn_Ribbon; pfam08273
696406015221	Toprim domain; Region: Toprim_3; pfam13362
696406015222	active site
696406015223	metal binding site [ion binding]; metal-binding site
696406015224	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
696406015225	Transposase; Region: DEDD_Tnp_IS110; pfam01548
696406015226	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
696406015227	Domain of unknown function (DUF4158); Region: DUF4158; pfam13700
696406015228	Tn3 transposase DDE domain; Region: DDE_Tnp_Tn3; pfam01526
696406015229	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
696406015230	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
696406015231	Presynaptic Site I dimer interface [polypeptide binding]; other site
696406015232	catalytic residues [active]
696406015233	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
696406015234	Synaptic Flat tetramer interface [polypeptide binding]; other site
696406015235	Synaptic Site I dimer interface [polypeptide binding]; other site
696406015236	DNA binding site [nucleotide binding]
696406015237	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
696406015238	DNA-binding interface [nucleotide binding]; DNA binding site
696406015239	integrase/recombinase; Provisional; Region: PRK15417
696406015240	IntI (E2) integrases, site-specific tyrosine recombinases, DNA breaking-rejoining enzymes, N- and C-terminal domains. This CD includes integrases which are components of multiresistant integrons and mediate recombination between a proximal attI site and...; Region: INT_IntI; cd01193
696406015241	Int/Topo IB signature motif; other site
696406015242	aminoglycoside resistance protein; Provisional; Region: PRK13746
696406015243	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
696406015244	active site
696406015245	NTP binding site [chemical binding]; other site
696406015246	metal binding triad [ion binding]; metal-binding site
696406015247	antibiotic binding site [chemical binding]; other site
696406015248	Domain of unknown function (DUF4111); Region: DUF4111; pfam13427
696406015249	YCII-related domain; Region: YCII; cl00999
696406015250	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
696406015251	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
696406015252	putative substrate translocation pore; other site
696406015253	aminoglycoside resistance protein; Provisional; Region: PRK13746
696406015254	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
696406015255	active site
696406015256	NTP binding site [chemical binding]; other site
696406015257	metal binding triad [ion binding]; metal-binding site
696406015258	antibiotic binding site [chemical binding]; other site
696406015259	Domain of unknown function (DUF4111); Region: DUF4111; pfam13427
696406015260	Small Multidrug Resistance protein; Region: Multi_Drug_Res; pfam00893
696406015261	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
696406015262	dihydropteroate synthase; Region: DHPS; TIGR01496
696406015263	substrate binding pocket [chemical binding]; other site
696406015264	dimer interface [polypeptide binding]; other site
696406015265	inhibitor binding site; inhibition site
696406015266	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
696406015267	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
696406015268	Coenzyme A binding pocket [chemical binding]; other site
696406015269	transposase/IS protein; Provisional; Region: PRK09183
696406015270	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
696406015271	Walker A motif; other site
696406015272	ATP binding site [chemical binding]; other site
696406015273	Walker B motif; other site
696406015274	arginine finger; other site
696406015275	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
696406015276	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
696406015277	Integrase core domain; Region: rve; pfam00665
696406015278	Transposase; Region: HTH_Tnp_1; pfam01527
696406015279	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
696406015280	putative transposase OrfB; Reviewed; Region: PHA02517
696406015281	HTH-like domain; Region: HTH_21; pfam13276
696406015282	Integrase core domain; Region: rve; pfam00665
696406015283	Integrase core domain; Region: rve_2; pfam13333
696406015284	Bacterial TniB protein; Region: TniB; pfam05621
696406015285	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3316
696406015286	Integrase core domain; Region: rve; pfam00665
696406015287	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
696406015288	Domain of unknown function (DUF3330); Region: DUF3330; pfam11809
696406015289	transcriptional regulator MerD; Provisional; Region: PRK13749
696406015290	Helix-Turn-Helix DNA binding domain of the MerD transcription regulator; Region: HTH_MerD; cd01111
696406015291	DNA binding residues [nucleotide binding]
696406015292	putative dimer interface [polypeptide binding]; other site
696406015293	alkylmercury lyase; Provisional; Region: PRK13239
696406015294	Helix-turn-helix domain of alkylmercury lyase; Region: HTH_15; pfam12324
696406015295	Alkylmercury lyase; Region: MerB; pfam03243
696406015296	putative mercuric reductase; Provisional; Region: PRK13748
696406015297	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
696406015298	metal-binding site [ion binding]
696406015299	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
696406015300	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
696406015301	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
696406015302	metal-binding site [ion binding]
696406015303	putative mercuric transport protein; Provisional; Region: PRK13751
696406015304	putative transcriptional regulator MerR; Provisional; Region: PRK13752
696406015305	Helix-Turn-Helix DNA binding domain of the MerR1 transcription regulator; Region: HTH_MerR1; cd04783
696406015306	DNA binding residues [nucleotide binding]
696406015307	dimer interface [polypeptide binding]; other site
696406015308	mercury binding site [ion binding]; other site
696406015309	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
696406015310	Transposase; Region: DEDD_Tnp_IS110; pfam01548
696406015311	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
696406015312	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
696406015313	RHS Repeat; Region: RHS_repeat; pfam05593
696406015314	RHS Repeat; Region: RHS_repeat; pfam05593
696406015315	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
696406015316	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
696406015317	RHS Repeat; Region: RHS_repeat; cl11982
696406015318	RHS protein; Region: RHS; pfam03527
696406015319	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
696406015320	Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; Region: PTPc; cl00053
696406015321	active site
696406015322	catalytic residues [active]
696406015323	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
696406015324	active site
696406015325	DNA binding site [nucleotide binding]
696406015326	Int/Topo IB signature motif; other site
696406015327	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
696406015328	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
696406015329	active site
696406015330	catalytic site [active]
696406015331	substrate binding site [chemical binding]; other site
696406015332	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
696406015333	Plasmid replication region DNA-binding N-term; Region: KfrA_N; pfam11740
696406015334	UvrD/REP helicase N-terminal domain; Region: UvrD-helicase; pfam00580
696406015335	Part of AAA domain; Region: AAA_19; pfam13245
696406015336	Family description; Region: UvrD_C_2; pfam13538
696406015337	conjugal transfer protein TrbB; Provisional; Region: PRK13728; cl17283
696406015338	F plasmid transfer operon protein; Region: TraF; pfam13728
696406015339	Conjugative relaxosome accessory transposon protein; Region: TraH; pfam06122
696406015340	TraG-like protein, N-terminal region; Region: TraG_N; pfam07916
696406015341	Winged helix-turn-helix DNA-binding; Region: HTH_35; cl17423
696406015342	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
696406015343	N-acetyl-D-glucosamine binding site [chemical binding]; other site
696406015344	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
696406015345	PRTRC system protein D; Region: PRTRC_D; TIGR03739
696406015346	Mg binding site [ion binding]; other site
696406015347	nucleotide binding site [chemical binding]; other site
696406015348	putative protofilament interface [polypeptide binding]; other site