-- dump date 20140619_080847 -- class Genbank::CDS -- table cds_note -- id note YP_003034267.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_003034268.1 binds the polymerase to DNA and acts as a sliding clamp YP_003034269.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_003034270.1 negatively supercoils closed circular double-stranded DNA YP_003034271.1 PFAM: protein of unknown function DUF937; KEGG: ssn:SSON_3648 hypothetical protein YP_003034272.1 YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins YP_003034273.1 KEGG: sfl:SF3768 hypothetical protein YP_003034274.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: sfx:S4002 regulator protein for dgo operon YP_003034275.1 PFAM: 2-keto-3-deoxy-galactonokinase; KEGG: ssn:SSON_3644 2-oxo-3-deoxygalactonate kinase YP_003034276.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism YP_003034277.1 PFAM: mandelate racemase/muconate lactonizing protein YP_003034278.1 TIGRFAM: d-galactonate transporter; phosphoglycerate transporter; PFAM: major facilitator superfamily MFS_1; general substrate transporter; KEGG: ssn:SSON_3642 D-galactonate transport YP_003034279.1 FAD/NAD(P)-binding domain YP_003034280.1 KEGG: ssn:SSON_3640 hypothetical protein YP_003034281.1 PFAM: protein of unknown function DUF1375; KEGG: sfv:SFV_3823 hypothetical protein YP_003034282.1 with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress YP_003034283.1 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent YP_003034284.1 TIGRFAM: YidE/YbjL duplication; PFAM: YidE/YbjL duplication domain protein; TrkA-C domain protein; KEGG: sfx:S3992 hypothetical protein YP_003034285.1 TIGRFAM: PTS system, alpha-glucoside-specific IIBC subunit; PTS system, maltose and glucose-specific subfamily, IIC subunit; PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system EIIC; phosphotransferase system PTS EIIB protein; KEGG: ssn:SSON_3634 phosphotransferase system enzyme IIBC component YP_003034286.1 PFAM: glycoside hydrolase family 4; KEGG: sdy:SDY_4168 6-phospho-beta-glucosidase YP_003034287.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type YP_003034288.1 uncharacterized member of the SSS superfamily of sodium-dependent solute transporters; unknown function YP_003034289.1 PFAM: sulfatase YP_003034290.1 KEGG: ssn:SSON_3631 hypothetical protein YP_003034291.1 PFAM: protein of unknown function DUF202; KEGG: sdy:SDY_4160 hypothetical protein YP_003034292.1 KEGG: sfv:SFV_3835 hypothetical protein YP_003034293.1 KEGG: sfv:SFV_3836 transcriptional regulator YP_003034294.1 multidrug efflux protein involved in adaptation to low energy shock YP_003034295.1 KEGG: sbc:SbBS512_E4246 hypothetical protein YP_003034296.1 KEGG: ses:SARI_03851 hypothetical protein YP_003034297.1 TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP-binding; KEGG: elf:LF82_1102 acetolactate synthase isozyme I large subunit YP_003034298.1 with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit YP_003034299.1 response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter YP_003034300.1 Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph YP_003034301.1 membrane protein regulates uhpT expression YP_003034302.1 cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate YP_003034303.1 catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type YP_003034304.1 PFAM: xanthine/uracil/vitamin C permease; sulfate transporter; KEGG: sbc:SbBS512_E4255 inorganic anion transporter sulfate permease (SulP) family YP_003034305.1 PFAM: protein of unknown function DUF1198; KEGG: sdy:SDY_4144 hypothetical protein YP_003034306.1 experimental results in Escherichia coli suggest that this gene encodes an inosine export protein; member of major facilitator superfamily; MFS YP_003034307.1 KEGG: sbo:SBO_3710 transporter YP_003034309.1 TIGRFAM: lipoprotein, YaeC family; PFAM: NLPA lipoprotein; KEGG: sdy:SDY_4499 cytoplasmic membrane lipoprotein-28 YP_003034310.1 TIGRFAM: carboxylate/amino acid/amine transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: elf:LF82_3359 uncharacterized inner membrane transporter YicL YP_003034311.1 TIGRFAM: sugar efflux transporter; PFAM: major facilitator superfamily MFS_1 YP_003034312.1 KEGG: ypb:YPTS_4098 hypothetical protein YP_003034313.1 KEGG: seh:SeHA_C4673 hypothetical protein YP_003034314.1 PFAM: protein of unknown function DUF957; KEGG: sfl:SF3001 hypothetical protein YP_003034315.1 KEGG: sfx:S3205 hypothetical protein YP_003034316.1 PFAM: protein of unknown function DUF1219; KEGG: sfx:S3204 hypothetical protein YP_003034317.1 PFAM: Integrase catalytic region YP_003034318.1 PFAM: transposase IS3/IS911 family protein; KEGG: sfv:SFV_4359 ISEhe3 orfA YP_003034319.1 TIGRFAM: outer membrane autotransporter barrel domain protein; autotransporter-associated beta strand repeat protein; PFAM: Autotransporter beta- domain protein; Pertactin; KEGG: cko:CKO_00426 hypothetical protein YP_003034321.1 KEGG: kpn:KPN_pKPN5p08236 hypothetical protein YP_003034322.1 PFAM: transposase IS3/IS911 family protein YP_003034323.1 KEGG: seh:SeHA_A0075 TrbC YP_003034324.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: cko:CKO_03842 single-stranded DNA-binding protein YP_003034325.1 PFAM: glycoside hydrolase family 31; KEGG: ssn:SSON_0800 glucosidase YP_003034326.1 PFAM: major facilitator superfamily MFS_1; KEGG: ssn:SSON_0801 hexuronate transporter YP_003034327.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; KEGG: ssn:SSON_0802 transcriptional regulator YP_003034329.1 KEGG: sfv:SFV_3869 hypothetical protein YP_003034330.1 PFAM: integrase; KEGG: ssn:SSON_3744 integrase YP_003034331.1 may be involved in the transport of galactosides-pentoses-hexuronides YP_003034332.1 catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides YP_003034333.1 PFAM: AsmA family protein; KEGG: sfx:S4074 hypothetical protein YP_003034334.1 TIGRFAM: uracil-xanthine permease; PFAM: xanthine/uracil/vitamin C permease; KEGG: ssn:SSON_3751 transport protein YP_003034335.1 TIGRFAM: sodium/glutamate symporter; PFAM: sodium/glutamate symporter; KEGG: sdy:SDY_4085 glutamate transport YP_003034336.1 KEGG: efe:EFER_3945 hypothetical protein YP_003034337.1 catalyzes branch migration in Holliday junction intermediates YP_003034338.1 specifically modifies tRNA at position G18 YP_003034339.1 KEGG: sfv:SFV_3879 bifunctional (p)ppGpp synthetase II/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; TIGRFAM: RelA/SpoT family protein; PFAM: RelA/SpoT domain protein; TGS domain protein; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region YP_003034340.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and subunit alphas YP_003034341.1 Essential for recycling GMP and indirectly, cGMP YP_003034342.1 this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+ YP_003034343.1 PFAM: protein of unknown function UPF0126; KEGG: sdy:SDY_4077 hypothetical protein YP_003034344.1 KEGG: sbc:SbBS512_E4096 DNA-damage-inducible protein D YP_003034345.1 KEGG: sbc:SbBS512_E4095 hypothetical protein YP_003034346.1 PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: ssn:SSON_3762 hypothetical protein YP_003034347.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_003034348.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_003034349.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly YP_003034350.1 catalyzes the formation of dUMP from dUTP YP_003034351.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine YP_003034352.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_003034353.1 required for 70S ribosome assembly YP_003034354.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_003034355.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_003034356.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_003034357.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A YP_003034358.1 TIGRFAM: lipopolysaccharide heptosyltransferase III; PFAM: glycosyl transferase family 9; KEGG: sdy:SDY_4062 lipopolysaccharide core biosynthesis protein YP_003034359.1 PFAM: glycosyl transferase group 1; KEGG: sfv:SFV_3900 LPS alpha1,3-glucosyltransferase YP_003034360.1 PFAM: lipopolysaccharide kinase; KEGG: sdy:SDY_4060 LPS biosynthesis enzyme YP_003034361.1 PFAM: glycosyl transferase family 8; glycosyl transferase family 8 domain protein; KEGG: sbo:SBO_3631 UDP-D-galactose:(glucosyl)lipopolysaccharide-alpha-1, 3-D-galactosylt ransferase YP_003034362.1 PFAM: Insertion element protein; KEGG: dps:DP0861 insertion element iso-IS1d protein (InsA) YP_003034363.1 PFAM: IS1 transposase; KEGG: dps:DP0860 insertion element IS1 1/5/6 protein (InsB) YP_003034364.1 PFAM: lipopolysaccharide core biosynthesis protein; KEGG: sdy:SDY_4057 lipopolysaccharide core biosynthesis protein YP_003034365.1 PFAM: glycosyl transferase family 8; glycosyl transferase family 8 domain protein; KEGG: ssn:SSON_3781 UDP-galactose:(galactosyl) LPS alpha1,2-galactosyltransferase YP_003034366.1 PFAM: glycosyl transferase family 2; KEGG: ssn:SSON_3782 beta1,3-glucosyltransferase YP_003034367.1 PFAM: O-antigen polymerase; KEGG: ssn:SSON_3783 lipid A-core, surface polymer ligase YP_003034368.1 TIGRFAM: lipopolysaccharide heptosyltransferase I; PFAM: glycosyl transferase family 9; KEGG: sbc:SbBS512_E4048 lipopolysaccharide heptosyltransferase I YP_003034369.1 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core YP_003034370.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose YP_003034371.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_003034372.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism YP_003034373.1 PFAM: glycosyl transferase family 2 YP_003034374.1 PFAM: protein of unknown function DUF610 YibQ; KEGG: sbc:SbBS512_E4043 polysaccharide deacetylase family protein YP_003034375.1 PFAM: peptidase M23 YP_003034376.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_003034377.1 PFAM: rhodanese; SMART: Rhodanese domain protein; KEGG: sbc:SbBS512_E4039 rhodanese domain protein YP_003034378.1 TIGRFAM: glutaredoxin; PFAM: glutaredoxin; KEGG: sfv:SFV_3921 glutaredoxin YP_003034379.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_003034380.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_003034381.1 catalyzes the O-acetylation of serine YP_003034382.1 member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates YP_003034383.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration YP_003034384.1 represses the lctPRD operon YP_003034385.1 TIGRFAM: L-lactate transport; PFAM: L-lactate permease; KEGG: sbc:SbBS512_E4029 L-lactate permease YP_003034386.1 PFAM: YadA domain protein; Hep_Hag repeat-containing protein; Haemagluttinin domain protein; KEGG: ssn:SSON_3803 adhesin YP_003034387.1 KEGG: sfv:SFV_3931 inner membrane lipoprotein YP_003034388.1 KEGG: sbc:SbBS512_E4020 hypothetical protein YP_003034389.1 KEGG: sfv:SFV_3935 cytoplasmic protein YP_003034390.1 Acts as a repressor of the mtlAD operon YP_003034391.1 PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: elf:LF82_1407 mannitol-1-phosphate 5-dehydrogenase YP_003034392.1 TIGRFAM: PTS system, mannitol-specific IIC subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; phosphotransferase system EIIC; phosphotransferase system lactose/cellobiose-specific IIB subunit YP_003034393.1 KEGG: ssn:SSON_3810 hypothetical protein YP_003034394.1 PFAM: secretion protein HlyD YP_003034396.1 KEGG: sbo:SBO_3594 hypothetical protein YP_003034397.1 PFAM: RHS protein; KEGG: sbo:SBO_3593 RhsA YP_003034398.1 PFAM: PBS lyase HEAT domain protein repeat-containing protein; KEGG: sei:SPC_1578 hypothetical protein YP_003034399.1 KEGG: sbo:SBO_0563 RhsC protein in rhs element YP_003034400.1 PFAM: glutathione S-transferase domain; KEGG: sbc:SbBS512_E4007 glutathione S-transferase YP_003034401.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis YP_003034402.1 TIGRFAM: selenocysteine-specific translation elongation factor; PFAM: protein synthesis factor GTP-binding; Elongation factor SelB winged helix 3; Elongation factor SelB winged helix 2; elongation factor Tu domain 2 protein; KEGG: elf:LF82_2111 selenocysteine-specific elongation factor YP_003034403.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: elf:LF82_3344 alcohol dehydrogenase YP_003034404.1 PFAM: aldehyde dehydrogenase; KEGG: sbc:SbBS512_E4003 aldehyde dehydrogenase B YP_003034405.1 KEGG: sfv:SFV_3946 hypothetical protein YP_003034407.1 PFAM: secretion protein HlyD YP_003034408.1 PFAM: regulatory protein LysR; LysR substrate-binding YP_003034409.1 PFAM: MltA-interacting MipA family protein; KEGG: sfv:SFV_3952 outer membrane protein YP_003034410.1 PFAM: protein of unknown function DUF1680; KEGG: sfv:SFV_3953 hypothetical protein YP_003034411.1 TIGRFAM: sugar (glycoside-Pentoside-Hexuronide) transporter; KEGG: sfv:SFV_3954 permease YP_003034412.1 PFAM: helix-turn-helix- domain containing protein AraC type; AraC protein arabinose-binding/dimerisation; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: sfv:SFV_3955 transcriptional regulator YP_003034413.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_003034414.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate YP_003034415.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate YP_003034416.1 PFAM: carbohydrate kinase FGGY; KEGG: sfv:SFV_3959 L-xylulose kinase, cryptic YP_003034417.1 TIGRFAM: TRAP dicarboxylate transporter DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: sfv:SFV_3960 solute-binding transporter YP_003034418.1 TIGRFAM: TRAP dicarboxylate transporter DctM subunit; PFAM: TRAP C4-dicarboxylate transporter permease DctM subunit YP_003034419.1 membrane-spanning protein involved in uptake of 2,3-diketo-L-gulonate; part of the tri-partite ATP-independent periplasmic transporter (TRAP) YiaMNO YP_003034420.1 PFAM: conserved hypothetical protein; KEGG: efe:EFER_3574 hypothetical protein YP_003034421.1 NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate YP_003034422.1 PFAM: transcriptional regulator IclR ; regulatory protein IclR; SMART: regulatory protein IclR; KEGG: sbo:SBO_3582 regulator YP_003034423.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sbo:SBO_3581 hypothetical protein YP_003034424.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis YP_003034425.1 periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds YP_003034426.1 PFAM: mannosyl-glycoprotein endo-beta-N-acetylglucosamidase; SMART: Lysozyme subfamily 2; KEGG: sfv:SFV_3970 hypothetical protein YP_003034427.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: sbc:SbBS512_E3953 xylose operon regulatory protein YP_003034428.1 PFAM: inner-membrane translocator; KEGG: sbc:SbBS512_E3954 D-xylose ABC transporter permease YP_003034429.1 periplasmic substrate-binding component of the ATP-dependent xylose transporter; high affinity YP_003034430.1 catalyzes the interconversion of D-xylose to D-xylulose YP_003034431.1 TIGRFAM: xylulokinase; PFAM: carbohydrate kinase FGGY; KEGG: sfv:SFV_3976 xylulokinase YP_003034432.1 PFAM: YiaAB two helix domain protein YP_003034433.1 PFAM: YiaAB two helix domain protein; KEGG: sfv:SFV_3978 hypothetical protein YP_003034434.1 PFAM: acyltransferase 3; KEGG: sdy:SDY_4340 hypothetical protein YP_003034435.1 KEGG: sfv:SFV_3980 lipoprotein YP_003034436.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_003034437.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_003034438.1 PFAM: Integrase catalytic region; KEGG: sfv:SFV_3530 IS150 ORF2 YP_003034439.1 KEGG: sfx:S1483 IS103 orf YP_003034440.1 PFAM: Hok/gef cell toxic protein; KEGG: elf:LF82_1021 protein HokA YP_003034441.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: sea:SeAg_B3864 major cold shock protein YP_003034442.1 SMART: helix-turn-helix domain protein; KEGG: sdy:SDY_4348 transcriptional regulator YP_003034444.1 KEGG: sdy:SDY_4349 hypothetical protein YP_003034445.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: sbc:SbBS512_E3973 2-ketogluconate reductase YP_003034446.1 PFAM: OmpA/MotB domain protein; 17 kDa surface antigen YP_003034447.1 KEGG: sbc:SbBS512_E3976 biotin sulfoxide reductase; TIGRFAM: molybdopterin guanine dinucleotide-containing S/N-oxide reductase; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region YP_003034448.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sbc:SbBS512_E3975 acetyltransferase, GNAT family YP_003034449.1 constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine YP_003034450.1 KEGG: sbc:SbBS512_E3978 hypothetical protein YP_003034451.1 TIGRFAM: Oxalate/formate antiporter; PFAM: major facilitator superfamily MFS_1; KEGG: ssn:SSON_3843 resistance protein YP_003034452.1 catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide YP_003034453.1 PFAM: extracellular solute-binding protein family 5; KEGG: sfv:SFV_3543 dipeptide transporter YP_003034454.1 transports peptides consisting of two or three amino acids YP_003034455.1 PFAM: binding-protein-dependent transporters inner membrane component YP_003034456.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transporter DppABCDF YP_003034457.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides YP_003034458.1 TIGRFAM: serine transporter; KEGG: ssn:SSON_3851 transporter protein YP_003034459.1 KEGG: sbc:SbBS512_E3995 hypothetical protein YP_003034460.1 KEGG: sbc:SbBS512_E3995 hypothetical protein YP_003034461.1 KEGG: sfl:SF3573 hypothetical protein YP_003034462.1 TIGRFAM: cellulose synthase operon protein YhjU; KEGG: sfv:SFV_3549 hypothetical protein YP_003034463.1 KEGG: sbc:SbBS512_E3999 cellulose biosynthesis protein BcsF YP_003034464.1 TIGRFAM: cellulose biosynthesis protein BcsE; KEGG: sfx:S4199 protease YP_003034465.1 KEGG: sfv:SFV_3553 hypothetical protein YP_003034466.1 TIGRFAM: cellulose synthase operon protein YhjQ; PFAM: YhjQ family protein; KEGG: sbc:SbBS512_E3940 YhjQ protein YP_003034467.1 polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis YP_003034468.1 binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP) YP_003034469.1 catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans YP_003034470.1 cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA YP_003034471.1 HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a phosphodiesterase protein from E. coli YP_003034472.1 involved in the transport of C4-dicarboxylates across the membrane YP_003034473.1 PFAM: peptidase M16 domain protein; KEGG: sdy:SDY_4547 hypothetical protein YP_003034474.1 PFAM: PfkB domain protein YP_003034475.1 in Escherichia coli this protein is involved in flagellar function YP_003034476.1 PFAM: AsmA family protein; KEGG: sbo:SBO_3523 hypothetical protein YP_003034477.1 TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: general substrate transporter; major facilitator superfamily MFS_1; KEGG: ssn:SSON_3868 transporter YP_003034478.1 TIGRFAM: ribonuclease; PFAM: ribonuclease BN; KEGG: sbc:SbBS512_E3927 ribonuclease YP_003034479.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: sbo:SBO_3520 transcriptional regulator LysR-type YP_003034480.1 PFAM: regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: regulatory protein LuxR; KEGG: sbc:SbBS512_E3925 transcriptional regulator, LuxR family YP_003034481.1 cytoplasmic; catalyzes the hydrolysis of trehalose to glucose YP_003034482.1 PFAM: Di-haem cytochrome C peroxidase; KEGG: sfv:SFV_3990 cytochrome C peroxidase YP_003034483.1 TIGRFAM: glutamate decarboxylase; PFAM: pyridoxal-dependent decarboxylase; KEGG: sbo:SBO_3516 glutamate decarboxylase isozyme YP_003034485.1 regulates genes in response to acid and/or during stationary phase YP_003034486.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: sfv:SFV_3987 AraC-type regulatory protein YP_003034487.1 TIGRFAM: transporter hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: sdy:SDY_3537 transporter permease YP_003034488.1 with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds YP_003034490.1 KEGG: sfv:SFV_3526 hypothetical protein YP_003034491.1 KEGG: sbc:SbBS512_E3909 HdeD protein YP_003034492.1 inactive form YP_003034493.1 KEGG: sfx:S4224 acid-resistance protein YP_003034494.1 inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli YP_003034495.1 PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR YP_003034496.1 TIGRFAM: outer membrane lipoprotein, Slp family; PFAM: outer membrane lipoprotein Slp; KEGG: sbc:SbBS512_E3904 outer membrane lipoprotein, Slp family YP_003034497.1 KEGG: sfv:SFV_3519 hypothetical protein YP_003034498.1 KEGG: sbc:SbBS512_E3818 arsenate reductase; TIGRFAM: arsenate reductase; PFAM: arsenate reductase YP_003034499.1 TIGRFAM: arsenical pump membrane protein; PFAM: Arsenical pump membrane protein; citrate transporter; KEGG: sbo:SBO_3500 arsenical pump membrane protein YP_003034500.1 regulates the expression of of the arsRBC involved in resistance to arsenic YP_003034501.1 KEGG: efe:EFER_3494 hypothetical protein YP_003034502.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_003034503.1 PFAM: protein of unknown function DUF519; KEGG: sbo:SBO_3497 hypothetical protein YP_003034504.1 PFAM: peptidase M3A and M3B thimet/oligopeptidase F YP_003034505.1 predicted SAM-dependent methyltransferase YP_003034506.1 member of the POT family of peptide transporters; probable proton-dependent peptide transporter function YP_003034507.1 PFAM: UspA domain protein; KEGG: cko:CKO_04943 hypothetical protein YP_003034508.1 ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress YP_003034509.1 PFAM: phosphate transporter; KEGG: sdy:SDY_3569 low-affinity phosphate transport YP_003034510.1 PFAM: HI0933 family protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; KEGG: sbc:SbBS512_E3830 pyridine nucleotide-disulfide oxidoreductase family protein YP_003034512.1 KEGG: sfl:SF3505 hypothetical protein YP_003034513.1 KEGG: sfx:S4259 hypothetical protein YP_003034514.1 PFAM: secretion protein HlyD; KEGG: sfv:SFV_3488 hypothetical protein YP_003034515.1 PFAM: ABC transporter; ABC-2 type transporter; SMART: ATPase AAA; KEGG: sbc:SbBS512_E3836 ABC transporter ATP binding protein YP_003034516.1 PFAM: ABC transporter; KEGG: sfv:SFV_3486 transporter YP_003034517.1 PFAM: transposase IS4 family protein; KEGG: ssn:SSON_0260 receptor YP_003034518.1 KEGG: sei:SPC_1578 hypothetical protein YP_003034520.1 TIGRFAM: hypothetical protein; PFAM: RHS protein; YD repeat-containing protein YP_003034521.1 Inhibits transcription at high concentrations of nickel YP_003034522.1 with NikABCD is involved with nickel transport into the cell YP_003034523.1 with NikABCE is involved in nickel transport into the cell YP_003034524.1 with NikABDE is involved in nickel transport into the cell YP_003034525.1 with NikACDE is involved in nickel transport into the cell YP_003034526.1 TIGRFAM: nickel ABC transporter periplasmic nickel-binding protein; PFAM: extracellular solute-binding protein family 5; KEGG: sfx:S4269 periplasmic binding protein for nickel YP_003034527.1 PFAM: 4'-phosphopantetheinyl transferase; KEGG: sbo:SBO_3472 holo-(acyl carrier protein) synthase 2 YP_003034528.1 PFAM: protein of unknown function UPF0118 YP_003034529.1 PFAM: major facilitator superfamily MFS_1; KEGG: sbc:SbBS512_E3849 transporter major facilitator family YP_003034530.1 KEGG: sdy:SDY_3623 hypothetical protein YP_003034531.1 TIGRFAM: conserved hypothetical protein; PFAM: protein of unknown function DUF165; KEGG: sbc:SbBS512_E3851 hypothetical protein YP_003034532.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs YP_003034533.1 P-type ATPase involved in the export of lead, cadmium, zinc and mercury YP_003034534.1 PFAM: YhhN family protein; KEGG: sbc:SbBS512_E3854 hypothetical protein YP_003034535.1 KEGG: sfv:SFV_3470 receptor YP_003034536.1 PFAM: protein of unknown function DUF1145; KEGG: sdy:SDY_3617 hypothetical protein YP_003034537.1 catalyzes the methylation of 16S rRNA at position G966 YP_003034538.1 signal recognition protein receptor; functions in the targeting and insertion of membrane proteins YP_003034539.1 ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions YP_003034540.1 ABC transporter membrane protein YP_003034541.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_003034542.1 PFAM: extracellular ligand-binding receptor; KEGG: sfv:SFV_3463 Leu/Ile/Val-binding protein precursor YP_003034543.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sdy:SDY_3610 hypothetical protein YP_003034544.1 PFAM: extracellular ligand-binding receptor; KEGG: sbc:SbBS512_E3864 high-affinity branched-chain amino acid ABC transporter periplasmic leucine-specific-binding protein LivK YP_003034545.1 LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter YP_003034546.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_003034547.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_003034548.1 with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transporter; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_003034549.1 with UgpACE is involved in the uptake of glycerol-3-phosphate YP_003034550.1 with UgpEC is involved in the uptake of glycerol-3-phosphate YP_003034551.1 with UgpABC is involved in uptake of glycerol-3-phosphate YP_003034552.1 part of the UgpABCE glycerol-3-phosphate uptake system YP_003034553.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate YP_003034554.1 KEGG: sfl:SF3465 hypothetical protein YP_003034555.1 periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides YP_003034556.1 KEGG: sbc:SbBS512_E3877 hypothetical protein YP_003034558.1 PFAM: Insertion element protein; KEGG: hdu:HD1971 insertion element IS1 1/2/3/5/6 protein InsA YP_003034559.1 KEGG: elf:LF82_3698 uncharacterized protein YrhA YP_003034560.1 TIGRFAM: type VI secretion system effector, Hcp1 family; PFAM: protein of unknown function DUF796; HNH endonuclease; KEGG: sbc:SbBS512_E3883 HNH endonuclease domain protein YP_003034561.1 YhhY; regulated by the fur regulator; unknown function YP_003034562.1 PFAM: oxidoreductase domain protein; oxidoreductase domain YP_003034563.1 PFAM: pirin; Cupin 2 conserved barrel domain protein; KEGG: sbc:SbBS512_E3886 pirin family protein YP_003034565.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; KEGG: efe:EFER_3414 DNA-binding transcriptional repressor YP_003034566.1 thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate YP_003034567.1 TIGRFAM: gluconate transporter; PFAM: gluconate transporter; citrate transporter; KEGG: sdy:SDY_3587 gluconate transporter low affinity GNT 1 system YP_003034568.1 YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP) YP_003034569.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_003034570.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_003034571.1 catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen YP_003034572.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_003034573.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_003034574.1 KEGG: sfv:SFV_3437 glycogen phosphorylase; TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35 YP_003034575.1 KEGG: sfv:SFV_3434 hypothetical protein YP_003034576.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_003034577.1 belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine YP_003034578.1 protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity YP_003034579.1 represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism YP_003034580.1 PFAM: regulator of RNA terminal phosphate cyclase; sigma-54 factor interaction domain-containing protein; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; KEGG: sfv:SFV_3429 2-component regulator YP_003034581.1 PFAM: protein of unknown function UPF0027 YP_003034582.1 catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester YP_003034583.1 PFAM: major facilitator superfamily MFS_1; KEGG: seh:SeHA_C4724 tetracycline resistance protein, class B YP_003034584.1 PFAM: Tetracyclin repressor domain protein; regulatory protein TetR; KEGG: apa:APP7_1823 tetracycline repressor protein TetR YP_003034585.1 KEGG: ssn:SSON_3549 maltodextrin phosphorylase; TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35 YP_003034586.1 amylomaltase; acts to release glucose from maltodextrins YP_003034587.1 TIGRFAM: gluconate transporter; PFAM: gluconate transporter; citrate transporter; KEGG: sbc:SbBS512_E3796 high-affinity gluconate transporter YP_003034588.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source YP_003034589.1 involved in high-affinity gluconate transport YP_003034590.1 Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis YP_003034591.1 PFAM: transposase YhgA family protein; KEGG: sbc:SbBS512_E3792 transposase, YhgA YP_003034592.1 PFAM: protein of unknown function DUF1920; KEGG: sdy:SDY_3666 hypothetical protein YP_003034593.1 cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake YP_003034594.1 PFAM: FeoA family protein; KEGG: sdy:SDY_3668 ferrous iron transporter A YP_003034595.1 PFAM: RNA binding S1 domain protein; SMART: Resolvase RNase H domain protein fold; RNA binding S1 domain protein; KEGG: sbc:SbBS512_E3786 transcriptional accessory protein YP_003034596.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_003034597.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation YP_003034598.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR YP_003034599.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_003034600.1 KEGG: sbc:SbBS512_E3781 hypothetical protein YP_003034601.1 KEGG: sbc:SbBS512_E3780 hypothetical protein YP_003034602.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_003034603.1 PFAM: RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; KEGG: sdy:SDY_3678 ribosome-associated heat shock protein HSP15 YP_003034604.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase; KEGG: sfv:SFV_3404 phosphatase YP_003034605.1 PFAM: Intracellular growth attenuator IgaA; KEGG: sfv:SFV_3403 dehydrogenase YP_003034606.1 KEGG: sbc:SbBS512_E3775 hypothetical protein YP_003034607.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_003034608.1 bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits YP_003034609.1 KEGG: ssn:SSON_3526 hypothetical protein YP_003034610.1 PFAM: fimbrial assembly family protein; KEGG: sfl:SF3412 hypothetical protein YP_003034611.1 KEGG: sfv:SFV_3398 hypothetical protein YP_003034612.1 KEGG: sdy:SDY_3687 hypothetical protein YP_003034613.1 outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa YP_003034614.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_003034615.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_003034616.1 PFAM: sporulation domain protein; KEGG: sbo:SBO_3375 hypothetical protein YP_003034617.1 KEGG: sbc:SbBS512_E3764 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase YP_003034618.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate YP_003034619.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate YP_003034620.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_003034622.1 KEGG: sbc:SbBS512_E3759 hypothetical protein YP_003034623.1 PFAM: alanine racemase domain protein; KEGG: sbc:SbBS512_E3758 alanine racemase family YP_003034624.1 PFAM: phosphopentomutase domain protein; metalloenzyme domain protein; KEGG: elf:LF82_3289 uncharacterized protein YhfW YP_003034625.1 phosphotriesterase homology protein; PhP; YhfV; member of a family of proteins related to phosphotriesterase (PTE) YP_003034626.1 KEGG: sfv:SFV_3383 hypothetical protein YP_003034627.1 KEGG: elf:LF82_3287 uncharacterized protein YhfT YP_003034628.1 PFAM: Insertion element protein; KEGG: hdu:HD1971 insertion element IS1 1/2/3/5/6 protein InsA YP_003034629.1 PFAM: IS1 transposase YP_003034630.1 may act as a transcriptional regulator of a fructoselysine-induced operon containing the yhfM, yhfN, yhfO, yhfP, yhfQ, and yhfR genes YP_003034631.1 PFAM: PfkB domain protein; KEGG: sbc:SbBS512_E3751 kinase, PfkB family YP_003034632.1 YhfOP; YhfP; YhfO; FrlC; catalyzes the interconversion of fructoselysine and psicoselysine YP_003034633.1 catalyzes the conversion of fructoselysine 6-phosphate to glucose 6-phosphate and lysine YP_003034634.1 inner membrane protein possibly involved in fructoselysine transport; member of the flr operon YP_003034635.1 KEGG: sbc:SbBS512_E3747 lipoprotein YP_003034636.1 multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin YP_003034637.1 member of the FNT family of formate and nitrite transporters YP_003034638.1 involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations YP_003034639.1 TIGRFAM: nitrite reductase [NAD(P)H], large subunit; PFAM: nitrite and sulphite reductase 4Fe-4S region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; KEGG: sbc:SbBS512_E3741 nitrite reductase [NAD(P)H], large subunit YP_003034640.1 PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_3346 hypothetical protein YP_003034641.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: sbc:SbBS512_E3738 peptidyl-prolyl cis-trans isomerase A YP_003034642.1 KEGG: sfv:SFV_3368 hypothetical protein YP_003034643.1 PFAM: filamentation induced by cAMP protein Fic; KEGG: sfv:SFV_3367 cell filamentation protein Fic YP_003034644.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity YP_003034645.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate YP_003034646.1 TIGRFAM: integral membrane protein, YccS/YhfK family; PFAM: protein of unknown function DUF893 YccS/YhfK; KEGG: sbc:SbBS512_E3734 integral membrane protein, YccS/YhfK family YP_003034647.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons YP_003034648.1 PFAM: OsmC family protein; KEGG: sdy:SDY_3518 hypothetical protein YP_003034649.1 PFAM: phosphoribulokinase/uridine kinase; KEGG: sfv:SFV_3361 phosphoribulokinase YP_003034650.1 PFAM: protein of unknown function UPF0270; KEGG: sbc:SbBS512_E3729 hypothetical protein YP_003034651.1 PFAM: alpha/beta hydrolase fold; KEGG: ssn:SSON_3484 predicted hydrolase YP_003034652.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: ssn:SSON_3483 ABC transporter ATP-binding protein YP_003034653.1 required for KefB activity YP_003034654.1 involved in potassium efflux YP_003034655.1 KEGG: sdy:SDY_3511 hypothetical protein YP_003034656.1 rotamase YP_003034657.1 PFAM: SlyX family protein; KEGG: sfv:SFV_3353 hypothetical protein YP_003034658.1 rotamase YP_003034659.1 PFAM: YheO domain protein; KEGG: sfx:S4398 hypothetical protein YP_003034660.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_003034661.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_003034662.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_003034663.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_003034664.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_003034665.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_003034666.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_003034668.1 KEGG: elf:LF82_0302 bifunctional chitinase/lysozyme; PFAM: carbohydrate-binding family V/XII; SMART: carbohydrate-binding family V/XII YP_003034670.1 PFAM: BFD domain protein [2Fe-2S]-binding domain protein; KEGG: elf:LF82_0223 bacterioferritin-associated ferredoxin YP_003034671.1 iron storage protein YP_003034672.1 PFAM: peptidase A24A prepilin type IV; KEGG: kpn:KPN_00149 pullulanase Q protein YP_003034673.1 PFAM: general secretion pathway M protein; KEGG: tau:Tola_0358 general secretion pathway M protein YP_003034674.1 TIGRFAM: general secretion pathway protein L; PFAM: general secretion pathway L; KEGG: elf:LF82_0949 general secretion pathway protein L YP_003034675.1 PFAM: general secretion pathway protein K; KEGG: elf:LF82_0948 general secretion pathway protein K YP_003034676.1 TIGRFAM: general secretion pathway protein J; KEGG: elf:LF82_0947 general secretion pathway protein J YP_003034677.1 TIGRFAM: general secretion pathway protein I; PFAM: type II secretion system protein I/J; KEGG: elf:LF82_0946 general secretion pathway protein I YP_003034678.1 TIGRFAM: general secretion pathway protein H; KEGG: elf:LF82_0945 general secretion pathway protein H YP_003034679.1 TIGRFAM: general secretion pathway protein G; PFAM: type II secretion system protein G; KEGG: elf:LF82_0944 general secretion pathway protein G YP_003034680.1 TIGRFAM: general secretion pathway protein F; PFAM: type II secretion system protein YP_003034681.1 KEGG: elf:LF82_0942 general secretion pathway protein E; TIGRFAM: general secretory pathway protein E; PFAM: type II secretion system protein E; SMART: ATPase AAA YP_003034682.1 PFAM: type II and III secretion system protein; NolW domain protein; KEGG: elf:LF82_0941 general secretion pathway protein D YP_003034683.1 TIGRFAM: general secretion pathway protein C; KEGG: elf:LF82_0940 general secretion pathway protein C YP_003034684.1 PFAM: peptidoglycan-binding protein; KEGG: elf:LF82_0938 general secretion pathway protein A YP_003034685.1 calcium-binding protein that may be required for the initiation of chromosome replication YP_003034686.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_003034687.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_003034688.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_003034689.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_003034690.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_003034691.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_003034692.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_003034693.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_003034694.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_003034695.1 one of the stabilizing components for the large ribosomal subunit YP_003034696.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_003034697.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_003034698.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_003034699.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_003034700.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_003034701.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_003034702.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_003034703.1 binds 5S rRNA along with protein L5 and L25 YP_003034704.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_003034705.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_003034706.1 late assembly protein YP_003034707.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_003034708.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_003034709.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_003034710.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_003034711.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_003034712.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_003034713.1 is a component of the macrolide binding site in the peptidyl transferase center YP_003034714.1 KEGG: ssn:SSON_3434 hypothetical protein YP_003034715.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators YP_003034716.1 PFAM: protein of unknown function DUF331; KEGG: ssn:SSON_3432 hypothetical protein YP_003034717.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock YP_003034718.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_003034719.1 catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase YP_003034720.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth YP_003034721.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_003034722.1 TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: elf:LF82_2142 protein smf YP_003034723.1 PFAM: protein of unknown function DUF494; KEGG: sfv:SFV_3304 hypothetical protein YP_003034724.1 PFAM: DNA topoisomerase type IA zn finger domain protein YP_003034725.1 RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA YP_003034726.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_003034727.1 PFAM: protein of unknown function DUF1488; KEGG: sfv:SFV_3301 hypothetical protein YP_003034728.1 KEGG: sfv:SFV_3300 transferase YP_003034729.1 PFAM: ABC transporter; SMART: ATPase AAA YP_003034730.1 TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: sdy:SDY_3447 transporter permease YP_003034731.1 TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component YP_003034732.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: elf:LF82_3270 amino-acid ABC transporter-binding protein YhdW YP_003034733.1 KEGG: sfv:SFV_3289 IS1 encoded protein YP_003034735.1 TIGRFAM: transporter hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: sbo:SBO_3260 integral transmembrane protein YP_003034736.1 TIGRFAM: efflux transporter RND family, MFP subunit; PFAM: secretion protein HlyD; KEGG: sbc:SbBS512_E3648 acriflavine resistance protein E YP_003034737.1 PFAM: Tetracycline transcriptional repressor MAATS-type domain protein; regulatory protein TetR; KEGG: sbc:SbBS512_E3647 transcriptional regulator EnvR YP_003034739.1 PFAM: DNA methylase N-4/N-6 domain protein; KEGG: ssn:SSON_3403 methyltransferase YP_003034740.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription YP_003034741.1 TIGRFAM: hypothetical protein; PFAM: dihydrouridine synthase; KEGG: sdy:SDY_3437 tRNA-dihydrouridine synthase B YP_003034742.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_003034743.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase YP_003034744.1 PFAM: protein of unknown function DUF997; KEGG: sdy:SDY_3434 hypothetical protein YP_003034745.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_003034746.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_003034748.1 TIGRFAM: quinone oxidoreductase, YhdH/YhfP family; PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: ssn:SSON_3394 dehydrogenase YP_003034749.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules YP_003034750.1 KEGG: sbc:SbBS512_E3283 hypothetical protein YP_003034751.1 functions in MreBCD complex in some organisms YP_003034752.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_003034753.1 part of cell wall structural complex MreBCD; transmembrane component YP_003034754.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_003034755.1 involved in the processing of the 5'end of 16S rRNA YP_003034756.1 KEGG: elf:LF82_3266 uncharacterized protein YhdP YP_003034757.1 responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA YP_003034758.1 KEGG: sbo:SBO_3144 DNA-binding transcriptional regulator YP_003034759.1 membrane protein AaeX; the gene is a member of the aaeXAB operon YP_003034760.1 with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_003034761.1 with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_003034762.1 KEGG: sdy:SDY_3415 hypothetical protein YP_003034763.1 KEGG: sbc:SbBS512_E3538 protein YcfR YP_003034764.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_003034765.1 KEGG: spq:SPAB_04187 hypothetical protein YP_003034766.1 oxidizes malate to oxaloacetate YP_003034767.1 KEGG: sfv:SFV_3262 serine endoprotease; TIGRFAM: periplasmic serine protease DegS; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein YP_003034768.1 KEGG: sbc:SbBS512_E3542 serine peptidase DegQ; TIGRFAM: protease Do; PFAM: PDZ/DHR/GLGF domain protein; peptidase S1 and S6 chymotrypsin/Hap; SMART: PDZ/DHR/GLGF domain protein YP_003034769.1 PFAM: protein of unknown function DUF1043; KEGG: elf:LF82_3254 cytochrome d ubiquinol oxidase subunit III YP_003034770.1 PFAM: AFG1-family ATPase; KEGG: sfv:SFV_3259 hypothetical protein YP_003034771.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_003034772.1 forms a direct contact with the tRNA during translation YP_003034773.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation YP_003034774.1 PFAM: stringent starvation protein B; KEGG: sfx:S3483 ClpXP protease specificity-enhancing factor YP_003034775.1 YhcL; uncharacterized member of the DcuC family of anaerobic dicarboxylate transporters; probable role in transport of carboxylates across the inner membrane from the periplasm; its encoding gene is not essential for growth and is probably cryptic YP_003034776.1 transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization YP_003034777.1 catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid YP_003034778.1 TIGRFAM: sialic acid transporter; PFAM: major facilitator superfamily MFS_1; general substrate transporter; KEGG: sbc:SbBS512_E3552 MFS transporter sialate:H+ symporter (SHS) family YP_003034779.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate YP_003034780.1 catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein YP_003034781.1 PFAM: conserved hypothetical protein; KEGG: sfv:SFV_3246 hypothetical protein YP_003034782.1 KEGG: sfx:S3473 IS600 orf YP_003034783.1 PFAM: protein of unknown function DUF1016; KEGG: elf:LF82_3256 uncharacterized protein YhcG YP_003034784.1 glutamate synthase is composed of subunits alpha and beta; subunit beta is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the subunit alpha, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_003034785.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate YP_003034786.1 KEGG: sbo:SBO_3171 hypothetical protein; TIGRFAM: conserved hypothetical protein; PFAM: radical SAM protein; SMART: Elongator protein 3/MiaB/NifB YP_003034787.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA YP_003034788.1 PFAM: ThiJ/PfpI domain protein; KEGG: sfv:SFV_3239 isoprenoid biosynthesis protein with amidotransferase-like domain YP_003034789.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan YP_003034790.1 KEGG: sfx:S3465 hypothetical protein YP_003034791.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr; KEGG: sfv:SFV_3236 phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr) YP_003034792.1 PFAM: conserved hypothetical protein; KEGG: sbc:SbBS512_E3565 hypothetical protein YP_003034793.1 TIGRFAM: PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: sfv:SFV_3234 PTS IIA-like nitrogen-regulatory protein PtsN YP_003034794.1 YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing YP_003034795.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_003034796.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: sdy:SDY_3382 ABC transporter ATP-binding protein YhbG YP_003034797.1 LptA; periplasmic binding protein part of a ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system YP_003034798.1 PFAM: protein of unknown function DUF1239; KEGG: sfv:SFV_3229 hypothetical protein YP_003034799.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis YP_003034800.1 KEGG: sbc:SbBS512_E3573 arabinose 5-phosphate isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: sugar isomerase (SIS); CBS domain containing protein YP_003034801.1 YrbG; inner membrane protein involved in cell envelope integrity; sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers YP_003034802.1 ATP-binding subunit of a ABC toluene efflux transporter YP_003034803.1 PFAM: protein of unknown function DUF140; KEGG: sbc:SbBS512_E3576 toluene ABC transporter permease YP_003034804.1 PFAM: hypothetical protein; KEGG: sbc:SbBS512_E3577 Mce family protein YP_003034805.1 PFAM: toluene tolerance family protein; KEGG: sfv:SFV_3222 hypothetical protein YP_003034806.1 KEGG: sfv:SFV_3221 hypothetical protein YP_003034807.1 PFAM: BolA family protein; KEGG: sfv:SFV_3220 hypothetical protein YP_003034808.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_003034809.1 activator of maltose metabolism genes YP_003034810.1 PFAM: polyprenyl synthetase; KEGG: sbo:SBO_3195 octaprenyl diphosphate synthase YP_003034811.1 TIGRFAM: ribosomal protein L21; PFAM: ribosomal protein L21; KEGG: sdy:SDY_3367 50S ribosomal protein L21 YP_003034812.1 involved in the peptidyltransferase reaction during translation YP_003034813.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: sbo:SBO_3198 hypothetical protein YP_003034814.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_003034815.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_003034816.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_003034817.1 RNA binding protein found associated to pre-50S subunit of the ribosome; role in ribosome assembly; necessary for optimal growth but not cell viability YP_003034818.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit YP_003034819.1 inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins YP_003034820.1 catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate YP_003034821.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_003034822.1 TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; KEGG: efe:EFER_3152 preprotein translocase membrane subunit YP_003034823.1 PFAM: sulfatase; KEGG: elf:LF82_3252 UPF0141 inner membrane protein YhbX YP_003034824.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis YP_003034825.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_003034826.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_003034827.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_003034828.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_003034829.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_003034830.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_003034831.1 KEGG: ssn:SSON_3310 polynucleotide phosphorylase/polyadenylase; PFAM: 3' exoribonuclease; polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type; RNA binding S1 domain protein; Exoribonuclease, phosphorolytic domain 2; KH type 1 domain protein; SMART: RNA binding S1 domain protein; KH domain protein YP_003034832.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing YP_003034833.1 participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division YP_003034834.1 tryptophan transporter of high affinity YP_003034835.1 PFAM: Luciferase-like monooxygenase; KEGG: sbo:SBO_3222 hypothetical protein YP_003034836.1 PFAM: peptidase U32; KEGG: sdy:SDY_3338 hypothetical protein YP_003034837.1 PFAM: peptidase U32; KEGG: sfv:SFV_3188 collagenase YP_003034838.1 PFAM: sterol-binding domain protein; KEGG: efe:EFER_3120 lipid carrier protein YP_003034839.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sdy:SDY_3335 hypothetical protein YP_003034840.1 PFAM: excinuclease ABC C subunit domain protein; SMART: excinuclease ABC C subunit domain protein; KEGG: sfv:SFV_3185 GIY-YIG nuclease superfamily protein YP_003034841.1 KEGG: sfv:SFV_3184 hypothetical protein YP_003034842.1 TIGRFAM: intracellular protease PfpI family; PFAM: ThiJ/PfpI domain protein; KEGG: sdy:SDY_3332 hypothetical protein YP_003034843.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: elf:LF82_3683 uncharacterized protein YraR YP_003034844.1 PFAM: permease; KEGG: ssn:SSON_3297 hypothetical protein YP_003034845.1 PFAM: transport-associated; SMART: transport-associated and nodulation region; KEGG: elf:LF82_3681 uncharacterized protein YraP YP_003034846.1 Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein YP_003034847.1 PFAM: protein of unknown function UPF0102; KEGG: ssn:SSON_3294 hypothetical protein YP_003034848.1 PFAM: LppC family lipoprotein; KEGG: ssn:SSON_3293 glycosylase YP_003034849.1 PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sdy:SDY_3325 hypothetical protein YP_003034850.1 KEGG: sfv:SFV_3175 fimbrial protein YP_003034851.1 PFAM: fimbrial biogenesis outer membrane usher protein YP_003034852.1 PFAM: Pili assembly chaperone, N-terminal; Pili assembly chaperone, C-terminal; KEGG: sfv:SFV_3171 chaperone YP_003034853.1 PFAM: fimbrial protein YP_003034854.1 PFAM: glucosamine/galactosamine-6-phosphate isomerase; KEGG: sfx:S3393 galactosamine-6-phosphate isomerase YP_003034855.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport YP_003034856.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane;protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport YP_003034857.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport YP_003034858.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway YP_003034859.1 TIGRFAM: sugar isomerase, AgaS family; PFAM: sugar isomerase (SIS) YP_003034860.1 KEGG: elf:LF82_p515 N-acetylgalactosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase YP_003034861.1 PFAM: PTS system fructose subfamily IIA component; KEGG: elf:LF82_p514 phosphotransferase system enzyme subunit IIA component) YP_003034862.1 PFAM: PTS system mannose/fructose/sorbose family IID component; KEGG: efe:EFER_4358 hexose/hexosamine family PTS permease IID component YP_003034863.1 PFAM: phosphotransferase system PTS sorbose-specific IIC subunit YP_003034864.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport YP_003034865.1 TIGRFAM: D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit; PFAM: D-tagatose-bisphosphate aldolase class II accessory protein AgaZ; KEGG: sfx:S3382 tagatose 6-phosphate kinase 2 YP_003034866.1 transcriptional repressor for the agaZVWA and agaSYBCDI operons YP_003034867.1 SohA; PrlF; involved in protein secretion; when overproduced or mutated, it induces growth defect and increased export of a reporter protein; a PrlF mutation induces the activity of the Lon protease and a Lon-deficient strain suppresses the phenotype conferred by the PrlF mutation YP_003034868.1 TIGRFAM: galactarate dehydratase; PFAM: D-galactarate dehydratase/altronate hydrolase domain protein; SAF domain protein YP_003034869.1 TIGRFAM: d-galactonate transporter; PFAM: major facilitator superfamily MFS_1 YP_003034870.1 cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate YP_003034871.1 catalyzes the reduction of tartronate semialdehyde to glycerate YP_003034872.1 KEGG: sbo:SBO_2989 glycerate kinase I; TIGRFAM: glycerate kinase; PFAM: glycerate kinase YP_003034873.1 KEGG: sfv:SFV_3162 hypothetical protein YP_003034875.1 participates in controlling the expression of several structural genes for the enzyme threonine dehydratase; TdcR activates the tdcABCDEFG operon YP_003034876.1 regulates the tdcABCDEFG operon which is involved in amino acid degradation YP_003034877.1 catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic YP_003034878.1 involved in the import of threonine and serine in combination with the import of a proton YP_003034879.1 catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism YP_003034880.1 KEGG: sbc:SbBS512_E3243 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical YP_003034881.1 TIGRFAM: endoribonuclease L-PSP; PFAM: endoribonuclease L-PSP; KEGG: sbc:SbBS512_E3244 endoribonuclease L-PSP YP_003034882.1 KEGG: sbc:SbBS512_E3245 L-serine ammonia-lyase TdcG; TIGRFAM: L-serine dehydratase; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain YP_003034883.1 TIGRFAM: serine transporter; KEGG: ssn:SSON_3268 transporter permease YP_003034884.1 PFAM: protein of unknown function DUF1063 YP_003034885.1 KEGG: sdy:SDY_3299 hypothetical protein YP_003034886.1 PFAM: pirin; KEGG: sbc:SbBS512_E3251 pirin family protein YP_003034887.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: sbo:SBO_2972 transcriptional regulator LysR-type YP_003034888.1 PFAM: protein of unknown function DUF805; KEGG: ssn:SSON_3263 cytochrome YP_003034889.1 PFAM: protein of unknown function DUF805; KEGG: sbc:SbBS512_E3258 inner membrane protein YhaH YP_003034891.1 KEGG: sdy:SDY_3291 transferase YP_003034892.1 PFAM: DoxX family protein YP_003034893.1 KEGG: sfv:SFV_3144 hypothetical protein YP_003034894.1 KEGG: sbc:SbBS512_E3262 hypothetical protein YP_003034895.1 PFAM: protein of unknown function DUF883 ElaB; KEGG: sdy:SDY_3285 hypothetical protein YP_003034896.1 PFAM: protein of unknown function DUF1090; KEGG: elf:LF82_3670 protein YqjC YP_003034897.1 KEGG: sbc:SbBS512_E3265 hypothetical protein YP_003034898.1 PFAM: SNARE associated Golgi protein; KEGG: sdy:SDY_3282 hypothetical protein YP_003034900.1 regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization. YP_003034901.1 TIGRFAM: d-galactonate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sfv:SFV_3134 transporter of hexuronates YP_003034902.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism YP_003034903.1 PFAM: D-galactarate dehydratase/altronate hydrolase domain protein; SAF domain protein; KEGG: sdy:SDY_3276 altronate hydrolase YP_003034904.1 KEGG: sfv:SFV_3131 hypothetical protein YP_003034905.1 involved in the import of serine and threonine coupled with the import of sodium YP_003034906.1 KEGG: efe:EFER_1021 hypothetical protein YP_003034907.1 PFAM: integral membrane protein TerC; KEGG: ssn:SSON_3117 transporter YP_003034908.1 KEGG: spq:SPAB_04023 hypothetical protein YP_003034909.1 PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: sfv:SFV_3128 hypothetical protein YP_003034910.1 PFAM: protein of unknown function DUF218; KEGG: sfv:SFV_3127 hypothetical protein YP_003034911.1 PFAM: protein of unknown function DUF45; KEGG: sdy:SDY_3268 hypothetical protein YP_003034912.1 PFAM: methyltransferase small; methyltransferase type 12; KEGG: sdy:SDY_3267 enzyme YP_003034913.1 KEGG: sfv:SFV_3124 hypothetical protein YP_003034914.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: sfv:SFV_3123 hypothetical protein YP_003034915.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; KEGG: ssn:SSON_3124 NADPH dehydrogenase YP_003034916.1 KEGG: sfl:SF3120 glycosyl hydrolase YP_003034917.1 KEGG: sbc:SbBS512_E3514 hypothetical protein YP_003034918.1 PFAM: amino acid permease-associated region; KEGG: sbo:SBO_2937 oxidoreductase YP_003034919.1 in Escherichia coli this is the second beta-galactosidase system YP_003034920.1 in Escherichia coli this is the second beta-galactosidase system YP_003034921.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI YP_003034922.1 PFAM: t-RNA-binding domain protein; KEGG: sbo:SBO_2933 hypothetical protein YP_003034923.1 catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate YP_003034924.1 KEGG: ssn:SSON_3210 aerotaxis sensor receptor, flavoprotein; TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; PAC repeat-containing protein YP_003034925.1 PFAM: transcriptional regulator PadR family protein; KEGG: sfv:SFV_3112 hypothetical protein YP_003034926.1 PFAM: FAD-binding 9 siderophore-interacting domain protein; Siderophore-interacting protein; KEGG: sbc:SbBS512_E3506 siderophore-interacting protein YP_003034927.1 PFAM: uracil-DNA glycosylase superfamily; KEGG: sfv:SFV_3109 G/U mismatch-specific DNA glycosylase YP_003034928.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria YP_003034929.1 synthesizes RNA primers at the replication forks YP_003034930.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_003034931.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_003034932.1 TIGRFAM: anion transporter; PFAM: sodium/sulfate symporter; KEGG: sfv:SFV_3103 hypothetical protein YP_003034933.1 Involved in the tartrate degradation pathway YP_003034934.1 Involved in the tartrate degradation pathway YP_003034935.1 activates expression of genes required for L-tartrate-dependent anaerobic growth on glycerol YP_003034936.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_003034937.1 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin YP_003034938.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_003034939.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases YP_003034940.1 SMART: SH3 domain protein; KEGG: sfv:SFV_3095 signal transduction protein YP_003034941.1 PFAM: adenylate cyclase; CHAD domain containing protein; KEGG: sdy:SDY_3237 hypothetical protein YP_003034942.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_003034943.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose YP_003034944.1 PFAM: band 7 protein; SMART: band 7 protein; KEGG: ssn:SSON_3188 hypothetical protein YP_003034945.1 PFAM: protein of unknown function DUF1449 YP_003034946.1 Involved in glycogen synthesis. May be involved in glycogen priming YP_003034947.1 KEGG: ssn:SSON_3184 hypothetical protein YP_003034948.1 PFAM: Pili assembly chaperone, N-terminal; KEGG: ssn:SSON_3183 hypothetical protein YP_003034949.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: elf:LF82_p510 hypothetical outer membrane usher protein YqiG YP_003034950.1 PFAM: fimbrial protein; KEGG: ssn:SSON_3180 predicted fimbrial-like adhesin protein YP_003034951.1 PFAM: protein of unknown function DUF526; KEGG: sfv:SFV_3086 hypothetical protein YP_003034952.1 DHBP synthase; functions during riboflavin biosynthesis YP_003034953.1 KEGG: sbc:SbBS512_E3475 hypothetical protein YP_003034954.1 PFAM: zinc/iron permease; KEGG: ssn:SSON_3177 zinc transporter ZupT YP_003034955.1 seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine YP_003034956.1 PFAM: glutathionylspermidine synthase; KEGG: sbc:SbBS512_E3470 glutathionylspermidine synthase family protein YP_003034957.1 PFAM: protein of unknown function DUF1190; KEGG: sfx:S3282 hypothetical protein YP_003034958.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell YP_003034959.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_003034960.1 PFAM: protein of unknown function DUF1249; KEGG: sfv:SFV_3078 hypothetical protein YP_003034961.1 PFAM: calcineurin phosphoesterase; metallophosphoesterase; KEGG: sdy:SDY_3208 cyclic 3',5'-adenosine monophosphate phosphodiesterase YP_003034962.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate YP_003034963.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_003034964.1 PFAM: antibiotic biosynthesis monooxygenase; KEGG: sfv:SFV_3074 hypothetical protein YP_003034965.1 PFAM: NAD(P)H dehydrogenase (quinone); KEGG: ssn:SSON_3166 modulator of drug activity B YP_003034966.1 KEGG: sfx:S3272 hypothetical protein YP_003034967.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: ssn:SSON_3165 sensor protein QseC YP_003034968.1 response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes YP_003034969.1 PFAM: conserved hypothetical protein; KEGG: sdy:SDY_3215 hypothetical protein YP_003034970.1 PFAM: transcription activator effector binding; KEGG: ssn:SSON_3162 hypothetical protein YP_003034971.1 KEGG: yps:YPTB3124 hypothetical protein YP_003034972.1 SMART: helix-turn-helix domain protein; KEGG: ypb:YPTS_3247 XRE family transcriptional regulator YP_003034973.1 YgiS; uncharacterized periplasmic protein that seems to be part of a binding-protein-dependent transporter YP_003034974.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_003034976.1 KEGG: sfv:SFV_3067 1-acyl-sn-glycerol-3-phosphate acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase YP_003034977.1 PFAM: multicopper oxidase type 3; multicopper oxidase type 2; KEGG: sbc:SbBS512_E3454 protein SufI YP_003034978.1 PFAM: radical SAM protein; radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_003034979.1 KEGG: sfv:SFV_3064 outer membrane lipoprotein YP_003034981.1 KEGG: sbc:SbBS512_E3441 hypothetical protein YP_003034982.1 methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate YP_003034983.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: sbc:SbBS512_E3439 alcohol dehydrogenase YqhD YP_003034984.1 PFAM: AraC-type transcriptional regulator; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: sbc:SbBS512_E3437 AraC family transcriptional regulator YP_003034985.1 PFAM: SNARE associated Golgi protein; KEGG: sfv:SFV_3059 hypothetical protein YP_003034986.1 catalyzes the formation of L-homocysteine from cystathionine YP_003034987.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell YP_003034988.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell YP_003034989.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sbc:SbBS512_E3432 oxidoreductase, short chain dehydrogenase/reductase family YP_003034990.1 PFAM: conserved hypothetical protein; KEGG: sbc:SbBS512_E3431 hypothetical protein YP_003034991.1 PFAM: aldo/keto reductase; KEGG: sfv:SFV_3053 aldo-keto reductase YP_003034992.1 PFAM: dienelactone hydrolase; KEGG: ssn:SSON_3144 predicted hydrolase YP_003034993.1 KEGG: sdy:SDY_3075 hypothetical protein YP_003034994.1 KEGG: sea:SeAg_B3324 hypothetical protein YP_003034995.1 involved in hydrogen uptake YP_003034996.1 Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2 YP_003034997.1 HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits YP_003034998.1 involved in hydrogen uptake YP_003034999.1 protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC) YP_003035000.1 KEGG: sbc:SbBS512_E3419 hydrogenase-2 operon protein HybE YP_003035001.1 plays a role in hydrogenase nickel cofactor insertion YP_003035002.1 TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: sdy:SDY_3083 hydrogenase 2 accessory protein HypG YP_003035003.1 YghU; B2989; one of eight glutathione transferase proteins from E. coli YP_003035004.1 catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction YP_003035005.1 PFAM: phosphate transporter; KEGG: ssn:SSON_3132 low-affinity phosphate transport YP_003035006.1 KEGG: sfx:S3234 hypothetical protein YP_003035007.1 KEGG: elf:LF82_3207 uncharacterized ATP-binding protein YghS YP_003035009.1 PFAM: polysaccharide biosynthesis protein; KEGG: elf:LF82_3205 inner membrane protein YghQ YP_003035010.1 PFAM: transposase IS4 family protein YP_003035012.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH YP_003035013.1 TIGRFAM: glycolate oxidase subunit GlcD; PFAM: FAD linked oxidase domain protein; KEGG: elf:LF82_0831 glycolate oxidase subunit GlcD YP_003035014.1 PFAM: FAD linked oxidase; KEGG: elf:LF82_0832 glycolate oxidase subunit GlcE YP_003035015.1 PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: elf:LF82_0833 glycolate oxidase iron-sulfur subunit YP_003035016.1 PFAM: protein of unknown function DUF336; KEGG: sfv:SFV_3032 hypothetical protein YP_003035017.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA YP_003035018.1 TIGRFAM: L-lactate transport; PFAM: L-lactate permease YP_003035019.1 KEGG: elf:LF82_3203 lipoprotein AcfD homolog YP_003035020.1 PFAM: peptidase A24A domain protein; peptidase A24A prepilin type IV; KEGG: efe:EFER_2912 bifunctional prepilin leader peptidase and methylase YP_003035021.1 KEGG: elf:LF82_3202 uncharacterized lipoprotein YghG YP_003035022.1 part of the general (type II) secretion pathway (GSP), a signal sequence-dependent process responsible for protein export; involved in trans-location of exoproteins from the cytoplasm to the periplasm YP_003035023.1 TIGRFAM: general secretion pathway protein L; PFAM: general secretion pathway L; KEGG: sbc:SbBS512_E3404 general secretion pathway protein GspL YP_003035024.1 PFAM: general secretion pathway M protein; KEGG: sbc:SbBS512_E3403 general secretion pathway protein M YP_003035025.1 PFAM: protein of unknown function DUF554; KEGG: ssn:SSON_3229 transporter YP_003035026.1 PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: elf:LF82_2159 ornithine decarboxylase, constitutive YP_003035027.1 PFAM: transposase IS4 family protein; KEGG: seh:SeHA_C4716 transposase (IS4 family) YP_003035028.1 PFAM: transposase IS4 family protein; KEGG: apa:APP7_1819 iso-IS10R ORF YP_003035029.1 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_003035030.1 PFAM: Fe(II) trafficking protein YggX; KEGG: sfv:SFV_3020 hypothetical protein YP_003035031.1 KEGG: sbo:SBO_3029 adenine DNA glycosylase; TIGRFAM: A/G-specific adenine glycosylase; PFAM: HhH-GPD family protein; helix-hairpin-helix motif; SMART: HhH-GPD family protein; iron-sulfur cluster loop YP_003035032.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_003035033.1 PFAM: protein of unknown function DUF469; KEGG: sdy:SDY_3113 hypothetical protein YP_003035034.1 KEGG: sbc:SbBS512_E3391 hypothetical protein YP_003035035.1 KEGG: sdy:SDY_3114 hypothetical protein YP_003035036.1 catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis YP_003035037.1 PFAM: protein of unknown function DUF1202; KEGG: sbc:SbBS512_E3388 hypothetical protein YP_003035038.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_003035039.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_003035040.1 PFAM: protein of unknown function DUF167; KEGG: sbc:SbBS512_E3385 hypothetical protein YP_003035041.1 PFAM: protein of unknown function YGGT; KEGG: sdy:SDY_3120 resistance protein YP_003035042.1 PFAM: alanine racemase domain protein; KEGG: sfv:SFV_3005 hypothetical protein YP_003035043.1 KEGG: sfv:SFV_3004 transporter; TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; SMART: ATPase AAA YP_003035044.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_003035045.1 PFAM: protein of unknown function DUF179; KEGG: sfv:SFV_3002 hypothetical protein YP_003035046.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_003035047.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_003035048.1 PFAM: endonuclease I; KEGG: sbc:SbBS512_E3377 endonuclease I YP_003035049.1 PFAM: protein of unknown function DUF335 SprT; SMART: protein of unknown function SprT; KEGG: sbo:SBO_3046 hypothetical protein YP_003035050.1 TIGRFAM: sugar transporter; PFAM: general substrate transporter; major facilitator superfamily MFS_1; KEGG: sdy:SDY_3129 galactose-proton symport of transporter YP_003035051.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_003035052.1 KEGG: sfv:SFV_2995 hypothetical protein YP_003035053.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_003035054.1 catalyzes the formation of putrescine from agmatine YP_003035055.1 PFAM: peptidase M48 Ste24p; KEGG: sbc:SbBS512_E3369 peptidase, M48B family YP_003035056.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_003035058.1 TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein YP_003035059.1 TIGRFAM: PTS system, mannitol-specific IIC subunit; PFAM: phosphotransferase system EIIC; phosphotransferase system lactose/cellobiose-specific IIB subunit; KEGG: sbc:SbBS512_E3365 PTS system, mannitol-specific cryptic EIICB component YP_003035060.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein YP_003035061.1 KEGG: sfv:SFV_2982 fructose-1,6-bisphosphatase II-like protein; TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein YP_003035062.1 PFAM: Mannitol repressor; KEGG: sbo:SBO_3059 DNA-binding transcriptional regulator YP_003035063.1 KEGG: efe:EFER_2860 conserved hypothetical protein; nucleoside triphosphate hydrolase domain YP_003035064.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate YP_003035065.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_003035066.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate YP_003035067.1 participates in the regulation of osmotic pressure changes within the cel YP_003035068.1 Involved in the export of arginine YP_003035069.1 PFAM: protein of unknown function DUF541; KEGG: sdy:SDY_3160 hypothetical protein YP_003035070.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sbc:SbBS512_E3344 transcriptional regulator, LysR family YP_003035071.1 KEGG: ssn:SSON_3071 coenzyme A transferase; TIGRFAM: succinate CoA transferase; PFAM: acetyl-CoA hydrolase/transferase YP_003035072.1 catalyzes the formation of propanoyl-CoA from methylmalonyl-CoA YP_003035073.1 functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transporters, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins YP_003035074.1 MDM; functions in conversion of succinate to propionate YP_003035075.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_003035076.1 KEGG: elf:LF82_3651 uncharacterized protein YqfE YP_003035077.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_003035078.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_003035079.1 ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function YP_003035080.1 PFAM: protein of unknown function DUF710; KEGG: sfv:SFV_2958 Z-ring-associated protein YP_003035081.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown YP_003035082.1 exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide YP_003035083.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone YP_003035084.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: ssn:SSON_3059 hypothetical protein YP_003035085.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_003035086.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_003035087.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_003035088.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: sbc:SbBS512_E3323 NAD dependent epimerase/dehydratase family YP_003035089.1 PFAM: glycoside hydrolase family 1; KEGG: sbo:SBO_3091 6-phospho-beta-glucosidase A; cryptic YP_003035090.1 PFAM: protein of unknown function DUF437; KEGG: ssn:SSON_3053 hypothetical protein YP_003035091.1 TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein; KEGG: sbc:SbBS512_E3320 channel protein, hemolysin III family YP_003035092.1 physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator YP_003035093.1 PFAM: protein of unknown function DUF339; KEGG: sbo:SBO_3095 hypothetical protein YP_003035094.1 PFAM: protein of unknown function DUF1434; KEGG: sbc:SbBS512_E3316 hypothetical protein YP_003035095.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic YP_003035096.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_003035097.1 DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity YP_003035098.1 5'-3' single-stranded-DNA-specific exonuclease YP_003035099.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1 YP_003035100.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_003035101.1 catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate YP_003035102.1 KEGG: sbc:SbBS512_E3307 hypothetical protein YP_003035103.1 TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: xanthine/uracil/vitamin C permease YP_003035104.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic) YP_003035105.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: ssn:SSON_3038 oxidoreductase, Fe-S subunit YP_003035106.1 PFAM: xanthine/uracil/vitamin C permease; sulfate transporter YP_003035107.1 Catalyzes the deamination of guanine YP_003035108.1 TIGRFAM: uracil-xanthine permease; xanthine permease; PFAM: xanthine/uracil/vitamin C permease YP_003035109.1 with YgfK and YgfM forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; molybdopterin-containing enzyme; oxidase activity toward hypoxanthine and xanthine can be detected if these substrates are present at high concentration YP_003035110.1 with YgfK and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfM contains a FAD domain YP_003035111.1 in Escherichia coli expression is induced in response to phase-specific signals and controlled by RpoS YP_003035112.1 with YgfM and YgfN forms a selenate reductase, which seems to catalyze the reduction of selenate to selenite; YgfK mutants are unable to reduce selenate; involved in purine salvage process; seems to act as an oxidoreductase, but sequence similarity suggests it is a dihydrothymine dehydrogenase YP_003035113.1 TIGRFAM: molybdenum hydroxylase accessory protein, YgfJ family; KEGG: elf:LF82_3171 uncharacterized protein YgfJ YP_003035115.1 TIGRFAM: selenium-dependent molybdenum hydroxylase system protein, YqeB family; PFAM: protein of unknown function DUF182; biotin/lipoyl attachment domain-containing protein; KEGG: sbo:SBO_3109 synthase YP_003035116.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP YP_003035117.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position YP_003035118.1 Zn-dependent extracellular dipeptidase; similar to succinyl-diaminopimelate desuccinylases YP_003035119.1 catalyzes the formation of pyruvate from 2,3-diaminopropionate YP_003035120.1 TIGRFAM: carbamoyltransferase YgeW; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; KEGG: elf:LF82_3165 uncharacterized protein YgeW YP_003035121.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: ATPase AAA; PAS domain containing protein; KEGG: ssn:SSON_3020 transcriptional regulator YP_003035122.1 iron-sulfur-binding subunit; with XdhA and XdhB participates in purine salvage YP_003035123.1 FAD-binding subunit; with XdhA and XdhC participates in purine salvage YP_003035124.1 molybdenum cofactor-binding protein; participates in purine salvage YP_003035125.1 PFAM: peptidase M23; peptidoglycan-binding LysM; SMART: peptidoglycan-binding LysM; KEGG: elf:LF82_3163 uncharacterized lipoprotein YgeR YP_003035126.1 KEGG: sfv:SFV_2926 hypothetical protein YP_003035127.1 PFAM: Integrase catalytic region; KEGG: sfv:SFV_1039 IS3 ORF2 YP_003035128.1 PFAM: transposase IS3/IS911 family protein YP_003035129.1 KEGG: ssn:SSON_3006 hypothetical protein YP_003035130.1 TIGRFAM: serine transporter; PFAM: Amino acid transporter transmembrane; KEGG: elf:LF82_3648 inner membrane transporter YqeG YP_003035131.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis YP_003035132.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate YP_003035133.1 PFAM: Integrase catalytic region; KEGG: sfv:SFV_3530 IS150 ORF2 YP_003035134.1 KEGG: sfx:S1483 IS103 orf YP_003035135.1 TIGRFAM: sugar transporter; PFAM: general substrate transporter; major facilitator superfamily MFS_1; KEGG: ssn:SSON_3001 low-affinity L-arabinose transporter proton symport protein YP_003035136.1 TIGRFAM: aspartate racemase; PFAM: Asp/Glu/hydantoin racemase; KEGG: sbc:SbBS512_E3023 Asp/Glu/hydantoin racemase YP_003035137.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase YP_003035138.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding YP_003035139.1 controls transcription of galETKM YP_003035140.1 transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1 YP_003035141.1 PFAM: major facilitator superfamily MFS_1; KEGG: sbc:SbBS512_E3027 lysophospholipid transporter YP_003035142.1 complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH YP_003035143.1 PFAM: protein of unknown function DUF903; KEGG: ssn:SSON_2990 hypothetical protein YP_003035144.1 PFAM: integral membrane protein TerC; KEGG: sdy:SDY_3049 transporter YP_003035145.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair YP_003035146.1 KEGG: elf:LF82_p452 hypothetical protein YgdT YP_003035147.1 hydrolyzes diadenosine polyphosphate YP_003035148.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr YP_003035149.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_003035150.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_003035151.1 KEGG: sdy:SDY_3043 hypothetical protein YP_003035152.1 KEGG: ssn:SSON_2982 hypothetical protein YP_003035153.1 KEGG: sbc:SbBS512_E3038 hypothetical protein YP_003035154.1 KEGG: sbc:SbBS512_E3039 prepilin peptidase-dependent protein C YP_003035155.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination YP_003035156.1 PFAM: peptidase M16 domain protein; KEGG: sfv:SFV_2899 protease III YP_003035157.1 helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_003035158.1 helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_003035159.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis YP_003035160.1 KEGG: sbc:SbBS512_E3045 N-acetylmuramoyl-L-alanine amidase AmiC; PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin YP_003035161.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues YP_003035162.1 PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: ssn:SSON_2969 enzyme YP_003035163.1 TIGRFAM: cysteine desulfurase, sulfur acceptor subunit CsdE; PFAM: Fe-S metabolism associated SufE; KEGG: ssn:SSON_2968 hypothetical protein YP_003035164.1 PFAM: aminotransferase class V; KEGG: ssn:SSON_2967 cysteine sulfinate desulfinase YP_003035165.1 PFAM: protein of unknown function DUF903; KEGG: ssn:SSON_2966 hypothetical protein YP_003035166.1 glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence YP_003035167.1 PFAM: protein of unknown function DUF423; KEGG: sdy:SDY_3025 hypothetical protein YP_003035169.1 regulates expression of genes involved in L-fucose utilization YP_003035170.1 PFAM: RbsD or FucU transport; KEGG: sdy:SDY_3022 protein of fucose operon YP_003035171.1 PFAM: carbohydrate kinase FGGY; KEGG: ssn:SSON_2960 L-fuculokinase YP_003035172.1 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose YP_003035173.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: atc:AGR_C_5112 ABC transporter protein, ATP binding component YP_003035174.1 PFAM: inner-membrane translocator; KEGG: hap:HAPS_1726 ABC D-ribose transporter permease RbsC YP_003035175.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: bcj:BCAM2280 solute-binding component of ABC transporter YP_003035176.1 PFAM: carbohydrate kinase FGGY; KEGG: pmr:PMI2941 probable carbohydrate kinase YP_003035177.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: pmr:PMI2934 LacI-family transcriptional regulator YP_003035178.1 PFAM: Insertion element protein; KEGG: hdu:HD1971 insertion element IS1 1/2/3/5/6 protein InsA YP_003035179.1 PFAM: IS1 transposase; KEGG: dps:DP0860 insertion element IS1 1/5/6 protein (InsB) YP_003035180.1 TIGRFAM: lactaldehyde reductase; PFAM: iron-containing alcohol dehydrogenase YP_003035181.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups YP_003035182.1 KEGG: ssn:SSON_2954 L-serine dehydratase; TIGRFAM: L-serine dehydratase; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain YP_003035183.1 TIGRFAM: serine transporter; KEGG: ssn:SSON_2953 probable serine transporter YP_003035185.1 PFAM: conserved hypothetical protein; KEGG: sbo:SBO_2676 hypothetical protein YP_003035186.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_003035187.1 SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function YP_003035188.1 PFAM: protein of unknown function DUF446; KEGG: ssn:SSON_2949 hypothetical protein YP_003035189.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp YP_003035190.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_003035191.1 TIGRFAM: d-galactonate transporter; PFAM: major facilitator superfamily MFS_1 YP_003035192.1 PFAM: mandelate racemase/muconate lactonizing protein; KEGG: ssn:SSON_2945 glucarate dehydratase YP_003035193.1 KEGG: sfx:S2994 glucarate dehydratase; TIGRFAM: glucarate dehydratase; PFAM: mandelate racemase/muconate lactonizing protein YP_003035194.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system YP_003035195.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S] YP_003035196.1 (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP YP_003035197.1 part of the MazF-MazE toxin-antitoxin system; conteracts MazF YP_003035198.1 MazF; endoribonuclease; toxin of the ChpA-ChpR toxin-antitoxin system YP_003035199.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era YP_003035200.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_003035201.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_003035202.1 PFAM: protein of unknown function DUF477; KEGG: sfv:SFV_2677 hypothetical protein YP_003035204.1 KEGG: sdy:SDY_2981 hypothetical protein YP_003035205.1 PFAM: carbohydrate kinase FGGY; KEGG: sdy:SDY_2978 kinase YP_003035206.1 PFAM: major facilitator superfamily MFS_1; KEGG: ssn:SSON_2927 transporter YP_003035207.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: elf:LF82_3153 uncharacterized oxidoreductase YgcW YP_003035208.1 PFAM: FAD linked oxidase YP_003035209.1 PFAM: major facilitator superfamily MFS_1; general substrate transporter; KEGG: ssn:SSON_2924 transporter YP_003035210.1 PFAM: electron transfer flavoprotein alpha/beta-subunit; KEGG: ssn:SSON_2923 transporter YP_003035211.1 PFAM: electron transfer flavoprotein subunit alpha; KEGG: ssn:SSON_2922 flavoprotein YP_003035212.1 PFAM: glycerol-3-phosphate responsive antiterminator; KEGG: elf:LF82_3148 uncharacterized protein YgcP YP_003035213.1 KEGG: sdy:SDY_2969 hypothetical protein YP_003035214.1 PFAM: FAD dependent oxidoreductase; monooxygenase FAD-binding; HI0933 family protein; KEGG: ssn:SSON_2919 hypothetical protein YP_003035215.1 TIGRFAM: 6-pyruvoyl tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: ssn:SSON_2918 6-pyruvoyl tetrahydrobiopterin synthase YP_003035216.1 catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity YP_003035217.1 hemoprotein; NADPH dependent; with the subunit alpha (a flavoprotein) catalyzes the reduction of sulfite to sulfide YP_003035218.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite YP_003035219.1 PFAM: Hok/gef cell toxic protein; KEGG: sbc:SbBS512_E3114 hok/gef family protein YP_003035221.1 PFAM: transposase IS4 family protein YP_003035222.1 catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3 YP_003035223.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_003035224.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ YP_003035225.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis YP_003035226.1 KEGG: sdy:SDY_2948 hypothetical protein YP_003035227.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein YP_003035228.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_003035229.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_003035230.1 catalyzes the modification of U13 in tRNA(Glu) YP_003035231.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_003035232.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins YP_003035233.1 outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus YP_003035234.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses YP_003035235.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function YP_003035236.1 PFAM: xylose isomerase; KEGG: sbc:SbBS512_E3135 AP endonuclease, family 2 YP_003035237.1 PFAM: class II aldolase/adducin family protein; KEGG: ssn:SSON_2886 aldolase YP_003035238.1 PFAM: type III effector Hrp-dependent outers; KEGG: ssn:SSON_2885 hypothetical protein YP_003035239.1 PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: sbc:SbBS512_E3138 NAD binding domain of 6-phosphogluconate dehydrogenase YP_003035240.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; SMART: regulatory protein DeoR; KEGG: sbo:SBO_2785 DeoR-type transcriptional regulator YP_003035241.1 PFAM: metallophosphoesterase; KEGG: sbo:SBO_2786 serine/threonine-specific protein phosphatase 2 YP_003035242.1 This protein performs the mismatch recognition step during the DNA repair process YP_003035244.1 KEGG: ssn:SSON_2879 hypothetical protein YP_003035245.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; GAF domain protein YP_003035246.1 TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein domain protein; AIR synthase related protein; KEGG: sbc:SbBS512_E3147 hydrogenase expression/formation protein HypE YP_003035247.1 TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: sbc:SbBS512_E3148 hydrogenase expression/formation protein HypD YP_003035248.1 HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase YP_003035249.1 GTP hydrolase involved in nickel liganding into hydrogenases YP_003035250.1 plays a role in hydrogenase nickel cofactor insertion YP_003035251.1 regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon YP_003035252.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sfv:SFV_2779 small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex) YP_003035253.1 catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3) YP_003035254.1 PFAM: respiratory-chain NADH dehydrogenase subunit 1; KEGG: ssn:SSON_2869 membrane-spanning protein of hydrogenase 3 (part of FHL complex) YP_003035255.1 PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; KEGG: sbo:SBO_2797 large subunit of hydrogenase 3 YP_003035256.1 electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate YP_003035257.1 PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: elf:LF82_1069 formate hydrogenlyase subunit 7 YP_003035258.1 PFAM: formate hydrogenlyase maturation HycH; KEGG: sbc:SbBS512_E3158 formate hydrogenlyase maturation protein YP_003035259.1 involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE YP_003035260.1 PFAM: glycoside hydrolase family 1; KEGG: ssn:SSON_2860 cryptic 6-phospho-beta-glucosidase YP_003035261.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_003035262.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: ssn:SSON_2858 ascBF operon repressor YP_003035263.1 involved in electron transport from formate to hydrogen YP_003035264.1 TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: SUA5/yciO/yrdC domain; acylphosphatase; zinc finger HypF domain protein; KEGG: ssn:SSON_2856 transcriptional regulatory protein YP_003035265.1 catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase YP_003035266.1 detoxifies nitric oxide using NADH YP_003035267.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon YP_003035268.1 catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate YP_003035269.1 regulates genes involved in glucitol utilization YP_003035270.1 regulator for glucitol utilization YP_003035271.1 catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate YP_003035272.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_003035273.1 KEGG: sbc:SbBS512_E3174 PTS system, glucitol/sorbitol-specific, IIB component; TIGRFAM: PTS system, glucitol/sorbitol-specific, IIBC subunit; PFAM: Sorbitol phosphotransferase protein II domain protein YP_003035274.1 TIGRFAM: PTS system, glucitol/sorbitol-specific, IIC subunit; PFAM: PTS system protein II sorbitol-specific factor; KEGG: sdy:SDY_2898 PTS system, glucitol/sorbitol-specific IIC component YP_003035275.1 membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan YP_003035276.1 PFAM: damage inducible protein CinA; KEGG: ssn:SSON_2844 competence damage-inducible protein A YP_003035277.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_003035278.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_003035279.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_003035280.1 affects carbohydrate metabolism; has regulatory role in many processes YP_003035281.1 YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent YP_003035282.1 KEGG: sfv:SFV_2815 hypothetical protein YP_003035283.1 involved in the first step of glutathione biosynthesis YP_003035284.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_003035285.1 TIGRFAM: drug resistance transporter EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1 YP_003035286.1 TIGRFAM: efflux pump membrane protein; PFAM: secretion protein HlyD family protein; KEGG: ssn:SSON_2829 multidrug resistance secretion protein YP_003035287.1 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB YP_003035288.1 KEGG: sbc:SbBS512_E3193 hypothetical protein YP_003035289.1 PFAM: AzlC family protein; KEGG: ssn:SSON_2826 hypothetical protein YP_003035290.1 PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_2836 permease YP_003035291.1 with ProVW, part of the high-affinity transporter for the osmoprotectant glycine betaine YP_003035292.1 with ProVX is involved in the high-affinity uptake of glycine betaine YP_003035293.1 with ProWX is involved in the high-affinity uptake of glycine betaine YP_003035294.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_003035295.1 Catalyzes the rate-limiting step in dNTP synthesis YP_003035296.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF YP_003035297.1 TIGRFAM: glutaredoxin-like protein NrdH; PFAM: glutaredoxin; KEGG: ssn:SSON_2818 glutaredoxin-like protein YP_003035298.1 PFAM: protein of unknown function DUF883 ElaB; KEGG: sdy:SDY_2863 hypothetical protein YP_003035299.1 KEGG: sbc:SbBS512_E3210 hypothetical protein YP_003035300.1 PFAM: protein of unknown function DUF1144; KEGG: sbc:SbBS512_E3211 hypothetical protein YP_003035301.1 PFAM: histone family protein nucleoid-structuring protein H-NS; SMART: histone family protein nucleoid-structuring protein H-NS; KEGG: sfx:S2883 DNA binding protein, nucleoid-associated YP_003035302.1 SMART: rhodanese; KEGG: sbc:SbBS512_E3213 inner membrane protein YP_003035303.1 PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; KEGG: sbo:SBO_2852 hypothetical protein YP_003035304.1 PFAM: protein of unknown function UPF0057; KEGG: sdy:SDY_2856 hypothetical protein YP_003035305.1 PFAM: peptidoglycan-binding LysM; transport-associated; SMART: peptidoglycan-binding LysM; transport-associated and nodulation region; KEGG: ssn:SSON_2809 hypothetical protein YP_003035306.1 regulator of gab gene expression YP_003035307.1 TIGRFAM: GABA permease; PFAM: amino acid permease-associated region; KEGG: sdy:SDY_2853 gamma-aminobutyrate transporter YP_003035308.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_003035309.1 catalyzes the formation of succinate from succinate semialdehyde; NADP dependent YP_003035310.1 catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate YP_003035311.1 in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution YP_003035312.1 PFAM: IS1 transposase YP_003035313.1 PFAM: Insertion element protein; KEGG: hdu:HD1971 insertion element IS1 1/2/3/5/6 protein InsA YP_003035314.1 PFAM: RepB plasmid partition; SMART: ParB domain protein nuclease; KEGG: ent:Ent638_2890 RepB plasmid partition YP_003035315.1 PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; KEGG: ent:Ent638_2889 nuclease YP_003035316.1 PFAM: Recombinase; Resolvase domain; KEGG: ent:Ent638_2888 recombinase YP_003035317.1 PFAM: integrase; KEGG: cko:CKO_03944 hypothetical protein YP_003035318.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_003035319.1 PFAM: cyclase/dehydrase; KEGG: efe:EFER_0454 hypothetical protein YP_003035320.1 PFAM: protein of unknown function UPF0125; KEGG: sbc:SbBS512_E3007 RnfH family protein YP_003035321.1 PFAM: SmpA/OmlA domain protein; KEGG: sdy:SDY_2790 hypothetical protein YP_003035322.1 TIGRFAM: DNA repair protein RecN; PFAM: SMC domain protein; KEGG: ssn:SSON_2772 recombination and repair protein YP_003035323.1 catalyzes the phosphorylation of NAD to NADP YP_003035324.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_003035325.1 PFAM: protein of unknown function DUF21; CBS domain containing protein; transporter-associated region; KEGG: sbc:SbBS512_E3001 CBS/transporter associated domain protein YP_003035326.1 PFAM: cytochrome C assembly protein; KEGG: sdy:SDY_2785 hypothetical protein YP_003035327.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins YP_003035328.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_003035329.1 Essential for efficient processing of 16S rRNA YP_003035330.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_003035331.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_003035332.1 PFAM: OmpA/MotB domain protein; KEGG: ssn:SSON_2762 predicted outer membrane lipoprotein YP_003035333.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein YP_003035334.1 KEGG: ssn:SSON_2755 hypothetical protein YP_003035336.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive YP_003035337.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis YP_003035338.1 catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis YP_003035339.1 associated with 30S ribosomal subunit; interferes with translation elongation YP_003035340.1 with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline YP_003035341.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA YP_003035342.1 PFAM: protein of unknown function DUF152; KEGG: sdy:SDY_2836 hypothetical protein YP_003035343.1 KEGG: sbo:SBO_2627 protein disaggregation chaperone; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: ATPase AAA-2 domain protein; ATPase AAA; Torsin; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: ATPase AAA YP_003035344.1 TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: general substrate transporter; major facilitator superfamily MFS_1; KEGG: sdy:SDY_2830 alpha-ketoglutarate transporter YP_003035345.1 KEGG: sbc:SbBS512_E2949 lipoprotein YP_003035346.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome YP_003035347.1 PFAM: GCN5-related N-acetyltransferase; CoA-binding domain protein; KEGG: sfx:S2819 hypothetical protein YP_003035348.1 PFAM: DTW domain containing protein; KEGG: sdy:SDY_2826 hypothetical protein YP_003035349.1 TIGRFAM: thioredoxin; PFAM: thioredoxin domain; KEGG: ssn:SSON_2708 thioredoxin 2 YP_003035350.1 PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: sdy:SDY_2824 predicted methyltransferase YP_003035351.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_003035352.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit YP_003035353.1 PFAM: lysine exporter (LYSE/YGGA); KEGG: sbc:SbBS512_E2958 translocator protein, LysE family YP_003035354.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: ssn:SSON_2703 transcriptional regulator LysR-type YP_003035355.1 facilitates an early step in the assembly of the 50S subunit of the ribosome YP_003035356.1 PFAM: methyltransferase small; KEGG: sfv:SFV_2638 enzyme YP_003035357.1 catalyzes the formation of oxaloacetate from L-aspartate YP_003035359.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_003035360.1 PFAM: anti sigma-E protein RseA family protein; anti sigma-E protein RseA domain protein; KEGG: efe:EFER_0502 anti-sigma factor YP_003035361.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP YP_003035362.1 involved in the reduction of the SoxR iron-sulfur cluster YP_003035363.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_003035364.1 catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins YP_003035365.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_003035366.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_003035367.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_003035368.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_003035369.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_003035370.1 KEGG: efe:EFER_0512 hypothetical protein YP_003035371.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sbc:SbBS512_E2927 4Fe-4S binding domain protein YP_003035372.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: ssn:SSON_2644 DNA-binding transcriptional regulator YP_003035373.1 TIGRFAM: HAD superfamily (subfamily IF) hydrolase, YfhB; KEGG: sbc:SbBS512_E2925 HAD hydrolase YhfB YP_003035374.1 PFAM: CMP/dCMP deaminase zinc-binding; KEGG: sbc:SbBS512_E2923 tRNA-specific adenosine deaminase YP_003035375.1 PFAM: IS1 transposase; KEGG: sty:HCM1.136a IS1 transposase YP_003035376.1 PFAM: Insertion element protein; KEGG: dps:DP0861 insertion element iso-IS1d protein (InsA) YP_003035377.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function YP_003035378.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_003035379.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sdy:SDY_2746 2-component sensor protein YP_003035380.1 KEGG: sfv:SFV_2603 hypothetical protein YP_003035381.1 PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; ATPase associated with various cellular activities AAA_5; SMART: response regulator receiver; ATPase AAA; KEGG: sbc:SbBS512_E2919 sigma-54 dependent response regulator YP_003035382.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA YP_003035383.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine YP_003035384.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_003035385.1 PFAM: ROK family protein; KEGG: sbo:SBO_2578 NAGC-like transcriptional regulator YP_003035386.1 PFAM: hypothetical protein; TPR repeat-containing protein; SMART: hypothetical protein; KEGG: sbo:SBO_2577 hypothetical protein YP_003035387.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: sfv:SFV_2596 LacI-type transcriptional regulator YP_003035388.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: sbo:SBO_2573 ATP-binding component of a transporter YP_003035389.1 PFAM: inner-membrane translocator; KEGG: ssn:SSON_2629 transporter permease YP_003035390.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: ssn:SSON_2628 oxidoreductase YP_003035391.1 PFAM: aldose 1-epimerase; KEGG: ssn:SSON_2627 hypothetical protein YP_003035392.1 PFAM: DoxX family protein; KEGG: sfx:S2762 hypothetical protein YP_003035393.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ssn:SSON_2624 phenylpropionate dioxygenase, ferredoxin reductase subunit YP_003035394.1 Converts cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol) into 3-(2,3-dihydroxylphenyl)propionate YP_003035395.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: ssn:SSON_2622 3-phenylpropionate dioxygenase ferredoxin subunit YP_003035396.1 PFAM: aromatic-ring-hydroxylating dioxygenase beta subunit; KEGG: sfx:S2758 3-phenylpropionate dioxygenase subunit beta YP_003035397.1 PFAM: Aromatic-ring-hydroxylating dioxygenase, alpha subunit-like; Rieske [2Fe-2S] domain protein; KEGG: ssn:SSON_2620 large terminal subunit of phenylpropionate dioxygenase YP_003035398.1 activator of 3-phenylpropionic acid catabolism YP_003035399.1 transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters YP_003035400.1 PFAM: PRD domain protein; KEGG: sbo:SBO_2559 stationary phase inducible protein CsiE YP_003035401.1 KEGG: sdy:SDY_2730 enzyme YP_003035402.1 PFAM: inositol monophosphatase; KEGG: sbo:SBO_2557 inositol monophosphatase YP_003035403.1 TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: sfv:SFV_2580 ATP synthase subunit beta YP_003035404.1 regulates the expression of the iscRSUA operon YP_003035405.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_003035406.1 TIGRFAM: FeS cluster assembly scaffold IscU; PFAM: nitrogen-fixing NifU domain protein; KEGG: ssn:SSON_2611 scaffold protein YP_003035407.1 forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein YP_003035408.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins YP_003035409.1 involved in the maturation of iron-sulfur cluster-containing proteins YP_003035410.1 TIGRFAM: ferredoxin 2Fe-2S type, ISC system; PFAM: ferredoxin; KEGG: sbc:SbBS512_E2900 ferredoxin 2Fe-2S type, ISC system YP_003035411.1 TIGRFAM: FeS assembly protein IscX; PFAM: protein of unknown function DUF528; KEGG: sdy:SDY_2720 hypothetical protein YP_003035412.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide YP_003035413.1 enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I YP_003035414.1 PFAM: Integrase catalytic region; KEGG: bcj:BCAS0612 integrase YP_003035415.1 KEGG: pnu:Pnuc_1431 ISPsy8, transposase OrfA YP_003035416.1 catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds YP_003035417.1 PFAM: alpha-2-macroglobulin; alpha-2-macroglobulin 2; KEGG: ssn:SSON_2602 hypothetical protein YP_003035418.1 penicillin-insensitive transglycosylase/transpeptidase YP_003035419.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_003035420.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_003035421.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: sbc:SbBS512_E2891 helix-turn-helix DNA-binding domain protein YP_003035422.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_003035423.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_003035424.1 KEGG: sdy:SDY_2709 hypothetical protein YP_003035425.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis YP_003035426.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_003035427.1 PFAM: protein of unknown function DUF1407; KEGG: sfv:SFV_2557 hypothetical protein YP_003035428.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_003035429.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_003035430.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_003035432.1 PFAM: 17 kDa surface antigen; KEGG: elf:LF82_3095 uncharacterized lipoprotein YfgH YP_003035434.1 KEGG: ssn:SSON_2586 hypothetical protein YP_003035436.1 PFAM: MASE1 domain protein; EAL domain protein; SMART: EAL domain protein; GGDEF domain containing protein; KEGG: ssn:SSON_2585 cytochrome C biogenesis protein YP_003035437.1 PFAM: Ppx/GppA phosphatase; KEGG: ssn:SSON_2584 exopolyphosphatase YP_003035438.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_003035439.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_003035440.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_003035441.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_003035442.1 TIGRFAM: uracil-xanthine permease; PFAM: xanthine/uracil/vitamin C permease; KEGG: ssn:SSON_2579 uracil transporter YP_003035443.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP YP_003035444.1 TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; KEGG: sdy:SDY_2684 oxidoreductase YP_003035445.1 PFAM: peptidase M48 Ste24p; KEGG: sfv:SFV_2539 hypothetical protein YP_003035446.1 PFAM: protein of unknown function UPF0118; KEGG: sdy:SDY_2682 permease YP_003035447.1 inner membrane protein presumed to act as a formate transporter; member of the hyf operon YP_003035448.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; SMART: GAF domain protein; ATPase AAA; KEGG: ssn:SSON_2572 2-component regulator, interaction with sigma 54 YP_003035449.1 PFAM: formate hydrogenlyase maturation HycH; KEGG: sfl:SF2534 protein processing element YP_003035450.1 PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: ssn:SSON_2570 hydrogenase 4 Fe-S subunit YP_003035451.1 probable electron transfer protein for hydrogenase 4; hydrogenase 4 is believed to be silent in E. coli under conditions tested so far YP_003035452.1 PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; KEGG: ssn:SSON_2568 hydrogenase 4 subunit YP_003035453.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: ssn:SSON_2567 hydrogenase 4 subunit F YP_003035454.1 interacts with formate dehydrogenase to produce an active formate hydrogenlyase complex which cleaves formate to dihydrogen and carbon dioxide YP_003035455.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: sfv:SFV_2529 hydrogenase 4 subunit D YP_003035456.1 KEGG: sfx:S2677 hydrogenase 4 subunit D YP_003035457.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: ssn:SSON_2563 hydrogenase 4 subunit B YP_003035458.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sfv:SFV_2526 hydrogenase 4 Fe-S subunit YP_003035459.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine YP_003035460.1 negative transcriptional regulator of the gcvTHP operon YP_003035461.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_003035462.1 PFAM: NlpBDapX family lipoprotein; KEGG: ssn:SSON_2558 lipoprotein YP_003035463.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_003035464.1 PFAM: protein of unknown function zinc metallopeptidase KEGG: sfv:SFV_2520 hypothetical protein YP_003035465.1 PFAM: protein of unknown function DUF699 ATPase ; GCN5-related N-acetyltransferase; KEGG: sfx:S2667 hypothetical protein YP_003035466.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate YP_003035467.1 KEGG: ssn:SSON_2553 inner membrane protein YP_003035468.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_003035469.1 PFAM: arsenate reductase; KEGG: ssn:SSON_2551 hypothetical protein YP_003035470.1 TIGRFAM: transporter hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein YP_003035471.1 KEGG: sdy:SDY_2653 nitrate/nitrite sensor protein NarQ; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein YP_003035472.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic) YP_003035473.1 PFAM: NUDIX hydrolase; KEGG: ssn:SSON_2547 hypothetical protein YP_003035474.1 PFAM: protein of unknown function DUF1176; KEGG: sbo:SBO_2482 hypothetical protein YP_003035475.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_003035476.1 KEGG: elf:LF82_2215 transaldolase A; TIGRFAM: transaldolase; PFAM: transaldolase YP_003035477.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate YP_003035478.1 PFAM: microcompartments protein; KEGG: sfv:SFV_2506 hypothetical protein YP_003035479.1 TIGRFAM: ethanolamine utilization protein, EutP; KEGG: sbc:SbBS512_E2827 ethanolamine utilization protein, EutP YP_003035480.1 PFAM: ethanolamine utilisation EutQ family protein; protein of unknown function DUF861 cupin_3; KEGG: ssn:SSON_2540 hypothetical protein YP_003035481.1 PFAM: cobalamin adenosyltransferase; KEGG: sbc:SbBS512_E2825 ethanolamine utilization cobalamin adenosyltransferase YP_003035482.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta YP_003035483.1 PFAM: microcompartments protein; KEGG: sbc:SbBS512_E2823 ethanolamine utilization protein EutM YP_003035484.1 PFAM: ethanolamine utilization protein EutN/carboxysome structural protein Ccml; KEGG: sbc:SbBS512_E2822 ethanolamine utilization protein YP_003035485.1 PFAM: aldehyde dehydrogenase; KEGG: sbo:SBO_2470 ethanolamine utilization YP_003035486.1 TIGRFAM: ethanolamine utilization protein EutJ family protein; KEGG: sbc:SbBS512_E2820 ethanolamine utilization protein EutJ YP_003035487.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: ssn:SSON_2533 EutG YP_003035489.1 PFAM: ethanolamine utilisation protein EutH; KEGG: ssn:SSON_2532 EutH YP_003035490.1 ethanolamine utilization protein EutA YP_003035491.1 PFAM: ethanolamine ammonia lyase large subunit; KEGG: sbc:SbBS512_E2816 ethanolamine ammonia-lyase, large subunit YP_003035492.1 catalyzes the formation of acetaldehyde from ethanolamine YP_003035493.1 PFAM: microcompartments protein; KEGG: sbc:SbBS512_E2811 ethanolamine utilization protein EutL YP_003035494.1 PFAM: microcompartments protein; KEGG: sbc:SbBS512_E2810 ethanolamine utilization protein EutK YP_003035495.1 activates the transcription of the ethanolamine utilization operon YP_003035496.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_003035497.1 KEGG: ssn:SSON_2524 N-acetylmuramoyl-L-alanine amidase I; PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin YP_003035498.1 PFAM: GCN5-related N-acetyltransferase; KEGG: ssn:SSON_2523 acetyltransferase YP_003035499.1 KEGG: ssn:SSON_2522 hypothetical protein YP_003035500.1 PFAM: protein of unknown function DUF1131; KEGG: sbc:SbBS512_E2804 lipoprotein YP_003035501.1 TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: sbc:SbBS512_E2803 dyp-type peroxidase family protein YP_003035502.1 belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component YP_003035503.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway YP_003035504.1 PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); KEGG: sbc:SbBS512_E2799 RpiR family transcriptional regulator YP_003035505.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; NAD-dependent epimerase/dehydratase; KEGG: ssn:SSON_2515 short chain dehydrogenase YP_003035506.1 TIGRFAM: sulfate ABC transporter periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: sdy:SDY_2621 thiosulfate transporter subunit YP_003035507.1 TIGRFAM: sulfate ABC transporter inner membrane subunit; sulfate ABC transporter inner membrane subunit CysT; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: sfv:SFV_2477 sulfate/thiosulfate transporter subunit YP_003035508.1 Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import YP_003035509.1 KEGG: sbo:SBO_2447 sulfate/thiosulfate transporter subunit; TIGRFAM: sulfate ABC transporter ATPase; PFAM: ABC transporter related; SMART: ATPase AAA YP_003035510.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide YP_003035511.1 PFAM: WGR domain protein; SMART: WGR domain protein; KEGG: sfv:SFV_2472 hypothetical protein YP_003035512.1 KEGG: sfv:SFV_2471 hypothetical protein YP_003035513.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal YP_003035514.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose YP_003035515.1 phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transporter YP_003035516.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr; KEGG: sea:SeAg_B2576 phosphohistidinoprotein-hexose phosphotransferase component of PTS system (HPr) YP_003035517.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis YP_003035519.1 role in sulfur assimilation YP_003035520.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure YP_003035521.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_003035522.1 KEGG: ssn:SSON_2499 cytoplasmic protein YP_003035523.1 PFAM: sodium symporter YP_003035524.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: sbc:SbBS512_E2773 LysR family transcriptional regulator YP_003035525.1 KEGG: sfl:SF2463 hypothetical protein YP_003035526.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_003035527.1 PFAM: protein of unknown function DUF1323; KEGG: sbc:SbBS512_E2780 hypothetical protein YP_003035528.1 PFAM: protein of unknown function DUF1323; KEGG: ssn:SSON_2489 hypothetical protein YP_003035529.1 PFAM: EAL domain protein; GGDEF domain containing protein; MASE1 domain protein; SMART: EAL domain protein; GGDEF domain containing protein; KEGG: sbo:SBO_2421 hypothetical protein YP_003035530.1 TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter domain protein; nucleoside recognition domain protein; Na+ dependent nucleoside transporter; KEGG: sfv:SFV_2450 permease of transport system for 3 nucleosides YP_003035531.1 TIGRFAM: Mn2+/Fe2+ transporter NRAMP family; PFAM: natural resistance-associated macrophage protein; KEGG: sbc:SbBS512_E2760 manganese transporter MntH YP_003035532.1 KEGG: ssn:SSON_2482 hypothetical protein YP_003035533.1 PFAM: chloride channel core; KEGG: sbc:SbBS512_E2758 chloride transporter chloride channel (ClC) family YP_003035534.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate YP_003035535.1 TIGRFAM: PTS system, fructose-specific, IIB subunnit; PFAM: phosphotransferase system PTS fructose-specific IIB subunit; KEGG: ssn:SSON_2479 PTS system enzyme IIB component YP_003035536.1 TIGRFAM: PTS system, fructose subfamily, IIC subunit; PFAM: phosphotransferase system EIIC; KEGG: sbc:SbBS512_E2755 PTS system, fructose-like, IIC component YP_003035537.1 Xaa-Pro aminopeptidase; limited methionine aminopeptidase YP_003035538.1 metalloprotein YP_003035539.1 TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PTS system, fructose subfamily, IIsubunit alpha; PFAM: PEP-utilizing protein; PEP-utilising protein mobile region; PEP-utilising protein domain protein; phosphoryl transfer system HPr; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: sfv:SFV_2441 PTS system enzyme IIA component, enzyme I YP_003035540.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: ssn:SSON_2474 AraC-type regulatory protein YP_003035541.1 PFAM: response regulator receiver; LytTr DNA-binding region; SMART: response regulator receiver; KEGG: sfx:S2585 2-component transcriptional regulator YP_003035542.1 KEGG: sbo:SBO_2406 sensor protein; PFAM: histidine kinase internal region; GAF domain protein; 5TM Receptors of the LytS-YhcK type transmembrane region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein YP_003035543.1 PFAM: aminotransferase class I and II YP_003035544.1 acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock YP_003035545.1 KEGG: ssn:SSON_2468 hypothetical protein YP_003035546.1 KEGG: ssn:SSON_2467 hypothetical protein YP_003035547.1 KEGG: sdy:SDY_2573 hypothetical protein YP_003035548.1 catalyzes the formation of oxalyl-CoA from oxalate and Formyl-CoA YP_003035549.1 catalyzes the formation of formyl-CoA from oxalyl-CoA YP_003035550.1 member of the AEC family of auxin efflux transporters; unknown function YP_003035551.1 PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: sbo:SBO_2397 hypothetical protein YP_003035552.1 PFAM: response regulator receiver; extracellular solute-binding protein family 3; Hpt domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: response regulator receiver; histidine kinase A domain protein; Hpt domain protein; extracellular solute-binding protein family 3; ATP-binding region ATPase domain protein; KEGG: sfv:SFV_2429 hybrid sensory histidine kinase in two-component regulatory system with EvgA YP_003035553.1 response regulator in two-component regulatory system with EvgS; phosphorylated EvgA activates ompC, emrKY, gadABC, hdeAB and others genes; involved in acid resistance, osmotic adaption, and drug resistance YP_003035554.1 TIGRFAM: efflux pump membrane protein; PFAM: secretion protein HlyD family protein; KEGG: sbc:SbBS512_E2737 drug resistance MFS transporter membrane fusion protein (MFP) subunit EmrK YP_003035555.1 TIGRFAM: drug resistance transporter EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_2393 multidrug resistance protein Y YP_003035556.1 catalyzes the formation of pyruvate from serine YP_003035557.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function YP_003035558.1 regulates the synthesis and expression of the dsdXA operon and dadA gene YP_003035559.1 PFAM: formate/nitrite transporter; KEGG: sdy:SDY_2551 transport YP_003035560.1 KEGG: cko:CKO_00445 hypothetical protein YP_003035561.1 PFAM: VacJ family lipoprotein; KEGG: sdy:SDY_2550 lipoprotein precursor YP_003035562.1 PFAM: Insertion element protein; KEGG: hdu:HD1971 insertion element IS1 1/2/3/5/6 protein InsA YP_003035563.1 PFAM: IS1 transposase YP_003035564.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: ssn:SSON_2400 long-chain fatty acid outer membrane transporter YP_003035565.1 PFAM: conserved hypothetical protein; KEGG: elf:LF82_3071 UPF0381 protein YfcZ YP_003035566.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth YP_003035567.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate YP_003035568.1 TIGRFAM: phosphohistidine phosphatase SixA; PFAM: phosphoglycerate mutase; KEGG: ssn:SSON_2396 phosphohistidine phosphatase YP_003035569.1 PFAM: fimbrial protein; KEGG: sfx:S2550 fimbrial-like protein YP_003035570.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: ssn:SSON_2394 PapC-like porin protein YP_003035571.1 PFAM: Pili assembly chaperone, N-terminal; KEGG: sfv:SFV_2405 chaperone YP_003035572.1 KEGG: elf:LF82_p369 hypothetical protein YfcR YP_003035573.1 PFAM: fimbrial protein; KEGG: sdy:SDY_2533 hypothetical protein YP_003035574.1 PFAM: fimbrial protein; KEGG: elf:LF82_p367 hypothetical fimbrial-like protein YfcP YP_003035575.1 KEGG: sfv:SFV_2401 hypothetical protein YP_003035576.1 PFAM: Smr protein/MutS2; SMART: Smr protein/MutS2; KEGG: elf:LF82_3070 UPF0115 protein YfcN YP_003035577.1 involved in methylation of ribosomal protein L3 YP_003035578.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_003035579.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm YP_003035580.1 PFAM: protein of unknown function DUF81; KEGG: sbc:SbBS512_E2705 hypothetical protein YP_003035581.1 PFAM: protein of unknown function DUF462; KEGG: ssn:SSON_2384 transporting ATPase YP_003035582.1 PFAM: YfcL protein; KEGG: sdy:SDY_2524 hypothetical protein YP_003035583.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules YP_003035584.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_003035585.1 PFAM: major facilitator superfamily MFS_1; KEGG: sfx:S2533 hypothetical protein YP_003035586.1 in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein YP_003035587.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: sbc:SbBS512_E2698 erythronate-4-phosphate dehydrogenase YP_003035588.1 PFAM: semialdehyde dehydrogenase dimerisation region; semialdehyde dehydrogenase NAD - binding; KEGG: ssn:SSON_2377 hypothetical protein YP_003035589.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_003035590.1 PFAM: SNARE associated Golgi protein; KEGG: sfv:SFV_2386 hypothetical protein YP_003035591.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_003035592.1 TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; KEGG: sfv:SFV_2384 bifunctional folylpolyglutamate synthase/dihydrofolate synthase YP_003035593.1 PFAM: sporulation domain protein; KEGG: ssn:SSON_2372 hypothetical protein YP_003035594.1 membrane protein required for colicin V production YP_003035595.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_003035596.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate YP_003035597.1 KEGG: sbc:SbBS512_E2688 lysine-arginine-ornithine-binding periplasmic protein; TIGRFAM: cationic amino acid ABC transporter periplasmic binding protein; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3 YP_003035598.1 KEGG: ssn:SSON_2367 histidine-binding periplasmic protein of high-affinity histidine transporter; TIGRFAM: cationic amino acid ABC transporter periplasmic binding protein; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3 YP_003035599.1 TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: sdy:SDY_2507 histidine transporter permease YP_003035600.1 TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: sdy:SDY_2506 histidine transport, membrane protein M YP_003035601.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: sbc:SbBS512_E2684 histidine ABC transporter ATP-binding protein YP_003035602.1 PFAM: transposase YhgA family protein; KEGG: sfv:SFV_2372 hypothetical protein YP_003035603.1 PFAM: hypothetical protein; Male sterility domain; NAD-dependent epimerase/dehydratase; KEGG: sbo:SBO_2339 sugar nucleotide epimerase YP_003035604.1 catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate YP_003035605.1 PFAM: glutathione S-transferase domain; KEGG: sbc:SbBS512_E2678 glutathione S-transferase YP_003035606.1 PFAM: glutathione S-transferase domain; KEGG: sbc:SbBS512_E2677 glutathione S-transferase domain protein YP_003035607.1 TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; KEGG: ssn:SSON_2357 phosphodiesterase YP_003035608.1 PFAM: NUDIX hydrolase; KEGG: sbc:SbBS512_E2675 hydrolase, NUDIX family protein YP_003035609.1 PFAM: C4-dicarboxylate anaerobic carrier; KEGG: sbc:SbBS512_E2674 C4-dicarboxylate anaerobic carrier protein YP_003035610.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_003035611.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_003035612.1 PFAM: protein of unknown function DUF412; KEGG: sdy:SDY_2491 hypothetical protein YP_003035613.1 PFAM: YfbU family protein; KEGG: ssn:SSON_2351 hypothetical protein YP_003035614.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: elf:LF82_3055 phosphatase YfbT YP_003035615.1 PFAM: citrate transporter; TrkA-C domain protein; TRAP C4-dicarboxylate transporter permease DctM subunit; KEGG: ssn:SSON_2349 transporter YP_003035616.1 PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region YP_003035617.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_003035619.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: elf:LF82_1233 HTH-type transcriptional regulator LrhA YP_003035621.1 Catalyzes the transfer of electrons from NADH to quinone YP_003035622.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_003035623.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms YP_003035624.1 Catalyzes the transfer of electrons from NADH to quinone YP_003035625.1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase YP_003035626.1 Catalyzes the transfer of electrons from NADH to quinone YP_003035627.1 Catalyzes the transfer of electrons from NADH to quinone YP_003035628.1 Catalyzes the transfer of electrons from NADH to quinone YP_003035629.1 Catalyzes the transfer of electrons from NADH to quinone YP_003035630.1 Catalyzes the transfer of electrons from NADH to quinone YP_003035631.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_003035632.1 Catalyzes the transfer of electrons from NADH to quinone YP_003035633.1 Catalyzes the transfer of electrons from NADH to quinone YP_003035634.1 PFAM: Integrase catalytic region; KEGG: bcj:BCAS0612 integrase YP_003035635.1 KEGG: pnu:Pnuc_1431 ISPsy8, transposase OrfA YP_003035636.1 PFAM: Domain of unknown function DUF1877; KEGG: sdy:SDY_2471 hypothetical protein YP_003035637.1 ElaD; specific cysteine protease which targets ubiquitin and ubiquitin-like proteins covalently bound to target proteins; SseL in Salmonella is required for macrophage killing and virulence, and it is secreted by the salmonella pathogenicity island 2 type III secretion system YP_003035638.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions YP_003035639.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sfv:SFV_2338 hypothetical protein YP_003035640.1 PFAM: protein of unknown function DUF883 ElaB; KEGG: sdy:SDY_2462 hypothetical protein YP_003035641.1 TIGRFAM: isochorismate synthase; PFAM: chorismate binding-like; KEGG: sfx:S2478 menaquinone-specific isochorismate synthase YP_003035642.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis YP_003035643.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA YP_003035644.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA YP_003035645.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate YP_003035646.1 TIGRFAM: O-succinylbenzoate-CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: sdy:SDY_2456 O-succinylbenzoic acid--CoA ligase YP_003035647.1 KEGG: ssn:SSON_2320 polymyxin resistance protein B YP_003035648.1 KEGG: ssn:SSON_2319 hypothetical protein YP_003035649.1 PFAM: small multidrug resistance protein; KEGG: sbc:SbBS512_E2634 multidrug resistance protein, SMR family YP_003035650.1 catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A YP_003035651.1 PFAM: polysaccharide deacetylase; KEGG: ssn:SSON_2317 hypothetical protein YP_003035652.1 Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains YP_003035653.1 catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate YP_003035654.1 catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose YP_003035655.1 PFAM: phosphoglycerate mutase; KEGG: ssn:SSON_2313 protein induced by aluminum YP_003035656.1 PFAM: NUDIX hydrolase; KEGG: elf:LF82_1535 NUDIX hydrolase YfaO YP_003035657.1 PFAM: YfaZ family protein YP_003035658.1 TIGRFAM: competence/damage-inducible protein CinA; molybdenum cofactor synthesis protein; PFAM: molybdopterin binding domain; KEGG: sfx:S2461 competence damage-inducible protein A YP_003035659.1 PFAM: transcriptional regulator IclR ; regulatory protein IclR; SMART: regulatory protein IclR; KEGG: ssn:SSON_2309 regulator YP_003035660.1 PFAM: mandelate racemase/muconate lactonizing protein; KEGG: sbo:SBO_2047 racemase YP_003035661.1 PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_2048 transporter YP_003035662.1 PFAM: HpcH/HpaI aldolase; KEGG: elf:LF82_3041 uncharacterized protein YfaU YP_003035663.1 PFAM: transposase YhgA family protein; KEGG: sbc:SbBS512_E2627 hypothetical protein YP_003035664.1 KEGG: sbc:SbBS512_E2626 hypothetical protein YP_003035665.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate YP_003035666.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters YP_003035667.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor YP_003035668.1 catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell YP_003035669.1 hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic YP_003035670.1 KEGG: sfx:S2453 hypothetical protein YP_003035671.1 PFAM: lipopolysaccharide kinase; KEGG: sfv:SFV_2310 hypothetical protein YP_003035672.1 plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases YP_003035673.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA YP_003035674.1 Catalyzes the rate-limiting step in dNTP synthesis YP_003035675.1 TIGRFAM: outer membrane autotransporter barrel domain protein; polymorphic outer membrane protein; autotransporter-associated beta strand repeat protein; PFAM: Autotransporter beta- domain protein; polymorphic membrane protein Chlamydia; Pertactin YP_003035676.1 Involved in ubiquinone biosynthesis YP_003035677.1 negatively supercoils closed circular double-stranded DNA YP_003035678.1 KEGG: elf:LF82_3033 uncharacterized protein YfaA YP_003035679.1 PFAM: protein of unknown function DUF1175 YP_003035680.1 PFAM: alpha-2-macroglobulin; alpha-2-macroglobulin 2 YP_003035681.1 KEGG: ssn:SSON_2285 hypothetical protein YP_003035682.1 KEGG: sfv:SFV_2294 hypothetical protein YP_003035683.1 KEGG: ssn:SSON_2283 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: thiolase YP_003035684.1 PFAM: short chain fatty acid transporter; KEGG: elf:LF82_0189 short-chain fatty acids transporter YP_003035685.1 KEGG: elf:LF82_0185 acetate CoA-transferase subunit beta; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase YP_003035686.1 KEGG: ssn:SSON_2280 acetyl-CoA:acetoacetyl-CoA transferase subunit alpha; TIGRFAM: 3-oxoacid CoA-transferase, subunit alpha; PFAM: coenzyme A transferase YP_003035687.1 with AtoS is a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism YP_003035688.1 with AtoC is a member of a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism YP_003035689.1 PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; KEGG: ssn:SSON_2277 hybrid sensory kinase in two-component regulatory system with RcsB and YojN YP_003035690.1 PFAM: Insertion element protein; KEGG: hdu:HD1971 insertion element IS1 1/2/3/5/6 protein InsA YP_003035691.1 PFAM: IS1 transposase; KEGG: sty:HCM1.136a IS1 transposase YP_003035692.1 catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway YP_003035693.1 KEGG: sbo:SBO_2094 O6-methylguanine-DNA methyltransferase; transcription activator/repressor; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; Ada metal-binding domain protein; helix-turn-helix- domain containing protein AraC type; methylguanine DNA methyltransferase ribonuclease domain protein; SMART: helix-turn-helix- domain containing protein AraC type YP_003035694.1 TIGRFAM: alkylated DNA repair protein AlkB; PFAM: 2OG-Fe(II) oxygenase; KEGG: sbc:SbBS512_E0728 alkylated DNA repair protein AlkB YP_003035695.1 efflux pump for the antibacterial peptide microcin J25 YP_003035696.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_003035697.1 serine protease inhibitor, inhibits trypsin and other proteases YP_003035698.1 KEGG: sbc:SbBS512_E0732 hypothetical protein YP_003035699.1 Predicted role in electron transfer to the periplasmic nitrate reductase protein NapA. YP_003035700.1 PFAM: NapD family protein; KEGG: ssn:SSON_2265 assembly protein for periplasmic nitrate reductase YP_003035701.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC YP_003035702.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway YP_003035703.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA YP_003035704.1 small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA YP_003035705.1 with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone YP_003035706.1 ATP-binding protein; required for proper cytochrome C maturation YP_003035707.1 PFAM: cytochrome C biogenesis protein CcmB; KEGG: sdy:SDY_0878 heme exporter protein B YP_003035708.1 PFAM: cytochrome C assembly protein; KEGG: sdy:SDY_0879 heme exporter protein C YP_003035709.1 PFAM: Heme exporter protein D (CcmD); KEGG: sdy:SDY_0880 heme exporter protein C YP_003035710.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome C maturation system; periplasmic protein anchored to the inner membrane YP_003035711.1 PFAM: cytochrome C assembly protein; KEGG: sbo:SBO_2111 cytochrome C biogenesis protein YP_003035712.1 PFAM: redoxin; alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; KEGG: sbc:SbBS512_E0746 thiol:disulfide interchange protein DsbE YP_003035713.1 PFAM: cytochrome C biogenesis protein; KEGG: sfv:SFV_2270 subunit of heme lyase YP_003035714.1 nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes YP_003035715.1 PFAM: Pertactin; Autotransporter beta- domain protein; KEGG: sfv:SFV_2268 ATP-binding component of a transport system YP_003035716.1 PFAM: sulfatase; KEGG: elf:LF82_3032 inner membrane protein YejM YP_003035717.1 PFAM: protein of unknown function DUF1414; KEGG: sbc:SbBS512_E0770 hypothetical protein YP_003035718.1 PFAM: 37kDa nucleoid-associated protein; KEGG: sfv:SFV_2264 nucleoid-associated protein NdpA YP_003035719.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_003035720.1 PFAM: type III restriction protein res subunit; helicase domain protein; DEAD/DEAH box helicase; SMART: DEAD-like helicase ; helicase; KEGG: sdy:SDY_0895 ATP-dependent helicase YP_003035721.1 catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA YP_003035722.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance YP_003035723.1 KEGG: sfv:SFV_2259 hypothetical protein YP_003035724.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: sdy:SDY_0899 ATP-binding component of a transporter YP_003035725.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: sbo:SBO_2145 transporter permease protein YP_003035726.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: ssn:SSON_2234 transporter permease protein YP_003035727.1 PFAM: extracellular solute-binding protein family 5 YP_003035728.1 PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: sbc:SbBS512_E0782 cyclic diguanylate phosphodiesterase YP_003035729.1 by similarity, Spr seems to have peptidase activity; involved in thermoresistance YP_003035730.1 PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; KEGG: ssn:SSON_2230 hypothetical protein YP_003035731.1 PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: sbc:SbBS512_E0785 CobW/P47K family protein YP_003035732.1 PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: ssn:SSON_2228 oxidoreductase YP_003035733.1 Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein YP_003035734.1 PFAM: protein of unknown function UPF0153; KEGG: elf:LF82_3023 UPF0153 protein YeiW YP_003035735.1 TIGRFAM: sugar efflux transporter; PFAM: major facilitator superfamily MFS_1 YP_003035736.1 phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr YP_003035737.1 converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers YP_003035738.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_003035739.1 PFAM: PfkB domain protein; KEGG: sfv:SFV_2241 hypothetical protein YP_003035740.1 PFAM: indigoidine synthase A family protein; KEGG: sfv:SFV_2240 hypothetical protein YP_003035741.1 TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter domain protein; nucleoside recognition domain protein; Na+ dependent nucleoside transporter; KEGG: sbc:SbBS512_E0801 nucleoside transporter NupC family YP_003035742.1 activator of nucleoside metabolism YP_003035743.1 Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively YP_003035744.1 TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter domain protein; nucleoside recognition domain protein; Na+ dependent nucleoside transporter; KEGG: ssn:SSON_2217 transport system permease YP_003035745.1 PFAM: PfkB domain protein; KEGG: sbc:SbBS512_E0806 kinase, PfkB family YP_003035746.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues YP_003035747.1 PFAM: conserved hypothetical protein; KEGG: sbo:SBO_2169 hypothetical protein YP_003035748.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: ssn:SSON_2213 DNA-binding transcriptional regulator YP_003035749.1 PFAM: amino acid permease-associated region; KEGG: sdy:SDY_2110 lysine transporter YP_003035750.1 Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein YP_003035751.1 KEGG: sbc:SbBS512_E0812 S-formylglutathione hydrolase; TIGRFAM: S-formylglutathione hydrolase; PFAM: esterase YP_003035752.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_003035753.1 PFAM: protein of unknown function DUF418; protein of unknown function DUF405; KEGG: sbc:SbBS512_E0814 hypothetical protein YP_003035754.1 negative regulator of the mglBAC operon for galactose utilization YP_003035755.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains YP_003035756.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex YP_003035757.1 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines YP_003035758.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain YP_003035759.1 KEGG: sbc:SbBS512_E0826 hypothetical protein YP_003035760.1 PFAM: protein of unknown function DUF218; KEGG: sfv:SFV_2219 hypothetical protein YP_003035761.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_003035762.1 PFAM: LrgB family protein; KEGG: sbc:SbBS512_E0829 LrgB family protein YP_003035763.1 PFAM: LrgA family protein; KEGG: sbo:SBO_1000 hypothetical protein YP_003035764.1 PFAM: dihydrouridine synthase; KEGG: elf:LF82_0533 tRNA-dihydrouridine synthase C YP_003035765.1 may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride YP_003035766.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sbc:SbBS512_E0834 3-oxoacyl-[acyl-carrier-protein] reductase YP_003035767.1 PFAM: SNARE associated Golgi protein; KEGG: sbc:SbBS512_E0835 hypothetical protein YP_003035768.1 PFAM: protein of unknown function DUF1282; KEGG: sbo:SBO_1009 hypothetical protein YP_003035769.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7 YP_003035770.1 component of the membrane-bound D-lactate oxidase FAD-binding, NADH independent YP_003035771.1 PFAM: glycoside hydrolase; KEGG: ssn:SSON_2189 beta-D-glucoside glucohydrolase, periplasmic YP_003035772.1 PFAM: substrate-binding region of ABC-type glycine betaine transporter; KEGG: sbo:SBO_1013 transporter permease YP_003035773.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: sbo:SBO_1014 transporter permease protein YP_003035774.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: elf:LF82_3005 uncharacterized ABC transporter ATP-binding protein YP_003035775.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: sbc:SbBS512_E0845 ABC transporter quaternary amine uptake (QAT) family, permease YP_003035776.1 KEGG: sdy:SDY_2161 hypothetical protein YP_003035777.1 PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: elf:LF82_1354 HTH-type transcriptional regulator MlrA YP_003035778.1 KEGG: sfx:S2325 2-component sensor protein; PFAM: histidine kinase internal region; GAF domain protein; 5TM Receptors of the LytS-YhcK type transmembrane region; ATP-binding region ATPase domain protein; SMART: GAF domain protein YP_003035779.1 unknown function; when overproduced it confers drug-resistance YP_003035780.1 PFAM: protein of unknown function DUF1456; KEGG: ssn:SSON_2170 hypothetical protein YP_003035781.1 PFAM: protein of unknown function DUF1307; KEGG: elf:LF82_3000 uncharacterized lipoprotein YehR YP_003035782.1 PFAM: zinc finger SWIM domain protein; KEGG: ssn:SSON_2168 hypothetical protein YP_003035783.1 PFAM: VWA containing CoxE family protein; SMART: von Willebrand factor A; KEGG: sbo:SBO_0944 hypothetical protein YP_003035784.1 KEGG: sfl:SF2189 hypothetical protein YP_003035785.1 PFAM: ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; KEGG: sfx:S2313 hypothetical protein YP_003035786.1 KEGG: efe:EFER_2203 hypothetical protein YP_003035788.1 PFAM: WGR domain protein; SMART: WGR domain protein; KEGG: efe:EFER_2201 molybdate metabolism regulator (MolR) YP_003035789.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_003035790.1 KEGG: sbc:SbBS512_E0855 mrp protein YP_003035791.1 PFAM: Insertion element protein; KEGG: dps:DP0861 insertion element iso-IS1d protein (InsA) YP_003035792.1 PFAM: IS1 transposase; KEGG: hdu:HD1970 insertion element IS1 1/5/6 protein InsB YP_003035796.1 KEGG: bvi:Bcep1808_7334 hypothetical protein YP_003035797.1 KEGG: noc:Noc_3027 hypothetical protein YP_003035798.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP YP_003035799.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_003035800.1 PFAM: glycoside hydrolase family 25; SMART: glycoside hydrolase family 25; KEGG: ssn:SSON_2150 hypothetical protein YP_003035801.1 PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: sdy:SDY_2274 transcriptional regulator YP_003035802.1 PFAM: PfkB domain protein; KEGG: sbo:SBO_0921 kinase YP_003035803.1 PFAM: ADP-ribosylation/crystallin J1; KEGG: ssn:SSON_2147 hypothetical protein YP_003035804.1 TIGRFAM: nucleoside transporter; PFAM: nucleoside:H symporter; major facilitator superfamily MFS_1; KEGG: sbc:SbBS512_E1140 nucleoside transporter YP_003035805.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate YP_003035806.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway YP_003035807.1 TIGRFAM: D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit; PFAM: D-tagatose-bisphosphate aldolase class II accessory protein AgaZ; KEGG: sbc:SbBS512_E1143 tagatose-6-phosphate kinase YP_003035808.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_003035809.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_003035810.1 TIGRFAM: PTS system, galactitol-specific IIC subunit; PFAM: PTS system Galactitol-specific IIC component YP_003035811.1 Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate YP_003035812.1 PFAM: IS1 transposase; KEGG: dps:DP0860 insertion element IS1 1/5/6 protein (InsB) YP_003035813.1 PFAM: Insertion element protein; KEGG: hdu:HD1971 insertion element IS1 1/2/3/5/6 protein InsA YP_003035814.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role YP_003035815.1 KEGG: sbo:SBO_0909 hypothetical protein YP_003035816.1 PFAM: peptidase U32; KEGG: ssn:SSON_2134 hypothetical protein YP_003035817.1 PFAM: protein of unknown function DUF1508; KEGG: ssn:SSON_2133 hypothetical protein YP_003035818.1 response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport YP_003035819.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: sbc:SbBS512_E1155 sensor histidine kinase BaeS YP_003035820.1 PFAM: major facilitator superfamily MFS_1; KEGG: sbc:SbBS512_E1156 multidrug resistance protein MdtD YP_003035821.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate YP_003035822.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate YP_003035823.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate YP_003035827.1 PFAM: von Willebrand factor A; SMART: von Willebrand factor A; KEGG: sbo:SBO_0899 hypothetical protein YP_003035828.1 KEGG: sbc:SbBS512_E1161 hypothetical protein YP_003035829.1 KEGG: sbc:SbBS512_E1162 hypothetical protein YP_003035830.1 KEGG: elf:LF82_2973 uncharacterized chaperone protein YegD YP_003035831.1 inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine YP_003035832.1 contains a MASE1 (membrane-Associated Sensor) domain; potentially involved in signal transduction YP_003035833.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_003035834.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_003035835.1 YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs YP_003035836.1 PFAM: integral membrane protein TerC; CBS domain containing protein; transporter-associated region; KEGG: sbo:SBO_0890 transporter YP_003035837.1 PFAM: polysaccharide export protein; KEGG: ssn:SSON_2115 polysaccharide export protein YP_003035838.1 Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis YP_003035839.1 Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide) YP_003035840.1 PFAM: glycosyl transferase family 2; KEGG: sfv:SFV_2118 glycosyl transferase YP_003035841.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium YP_003035842.1 KEGG: ssn:SSON_2110 predicted glycosyl transferase YP_003035843.1 essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance YP_003035844.1 PFAM: glycosyl transferase family 2; KEGG: ssn:SSON_2108 predicted glycosyl transferase YP_003035845.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit) YP_003035846.1 TIGRFAM: GDP-mannose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; KEGG: ssn:SSON_2106 GDP-D-mannose dehydratase YP_003035847.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: ssn:SSON_2105 nucleotide di-P-sugar epimerase or dehydratase YP_003035848.1 PFAM: NUDIX hydrolase; KEGG: ssn:SSON_2104 GDP-mannose mannosyl hydrolase YP_003035849.1 PFAM: glycosyl transferase group 1; KEGG: sfx:S2236 glycosyl transferase YP_003035850.1 KEGG: elf:LF82_0345 mannose-1-phosphate guanylyltransferase [GDP]; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: nucleotidyl transferase; cupin; mannose-6-phosphate isomerase type II YP_003035851.1 PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase; KEGG: efe:EFER_2132 phosphomannomutase YP_003035852.1 WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid YP_003035853.1 PFAM: polysaccharide biosynthesis protein YP_003035854.1 PFAM: polysaccharide pyruvyl transferase; KEGG: sbo:SBO_0872 pyruvyl transferase YP_003035855.1 PFAM: glycosyl transferase group 1; KEGG: efe:EFER_2128 glycosyl transferase YP_003035856.1 WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid YP_003035857.1 together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose YP_003035858.1 NAD(P) binding; catalyzes the formation of dTDP-4-dehydro-6-deoxy-D-glucose from dTDP-glucose YP_003035859.1 with dTDP-4-dehydrorhamnose 3,5-epimerase forms a complex known as dTDP-L-rhamnose synthetase; catalyzes the reduction of dTDP-4-dehydro-6-deoxy-L-mannose to dTDP-L-rhamnose YP_003035860.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: nucleotidyl transferase; KEGG: sfv:SFV_2096 glucose-1-phosphate thymidylyltransferase YP_003035861.1 KEGG: sfv:SFV_2095 dTDP-6-deoxy-L-mannose-dehydrogenase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 35-epimerase related YP_003035862.1 PFAM: polysaccharide biosynthesis protein; KEGG: shw:Sputw3181_1467 polysaccharide biosynthesis protein YP_003035863.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: she:Shewmr4_1321 DegT/DnrJ/EryC1/StrS aminotransferase YP_003035864.1 KEGG: she:Shewmr4_1322 acetyltransferase YP_003035865.1 KEGG: pub:SAR11_0820 rhamnosyltransferase YP_003035867.1 KEGG: son:SO_3179 lipopolysaccharide biosynthesis polymerase YP_003035868.1 PFAM: glycosyl transferase group 1; KEGG: aci:ACIAD0084 mannosyl transferase YP_003035869.1 PFAM: Insertion element protein; KEGG: hdu:HD1971 insertion element IS1 1/2/3/5/6 protein InsA YP_003035870.1 PFAM: IS1 transposase; KEGG: sty:HCM1.136a IS1 transposase YP_003035871.1 KEGG: efe:EFER_2133 mannose-1-phosphate guanyltransferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: nucleotidyl transferase; cupin; mannose-6-phosphate isomerase type II YP_003035872.1 PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase; KEGG: ssn:SSON_2101 phosphomannomutase YP_003035873.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_003035874.1 TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase YP_003035875.1 PFAM: lipopolysaccharide biosynthesis protein; KEGG: ssn:SSON_2098 regulator of length of O-antigen component of lipopolysaccharide chains YP_003035876.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis YP_003035877.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_003035878.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_003035879.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_003035880.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate YP_003035881.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_003035882.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_003035883.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_003035884.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: ssn:SSON_2086 enzyme of sugar metabolism YP_003035885.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: ssn:SSON_2085 transcriptional regulator LysR-type YP_003035886.1 PFAM: amino acid permease-associated region; KEGG: sdy:SDY_2226 amino acid/amine transporter YP_003035887.1 PFAM: protein of unknown function DUF395 YeeE/YedE; KEGG: efe:EFER_2096 conserved hypothetical protein; inner membrane protein YP_003035888.1 PFAM: SirA family protein; KEGG: ssn:SSON_2082 hypothetical protein YP_003035889.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates YP_003035890.1 removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_003035891.1 PFAM: transcription activator effector binding YP_003035893.1 PFAM: protein of unknown function DUF496; KEGG: ssn:SSON_2077 hypothetical protein YP_003035895.1 KEGG: cko:CKO_02654 hypothetical protein YP_003035896.1 catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP YP_003035897.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole YP_003035898.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole YP_003035899.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: sdy:SDY_2243 hypothetical protein YP_003035900.1 transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation YP_003035901.1 LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB YP_003035902.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: ssn:SSON_2044 predicted multidrug efflux system YP_003035903.1 PFAM: protein of unknown function DUF28; KEGG: sbo:SBO_1217 hypothetical protein YP_003035904.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile YP_003035905.1 TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: major facilitator superfamily MFS_1; general substrate transporter YP_003035906.1 PFAM: Ig domain protein group 1 domain protein; SMART: Ig domain protein group 1 domain protein; PKD domain containing protein YP_003035908.1 PFAM: protein of unknown function DUF980; KEGG: ssn:SSON_2035 hypothetical protein YP_003035909.1 PFAM: transposase IS4 family protein; KEGG: apa:APP7_1819 iso-IS10R ORF YP_003035910.1 PFAM: YodA domain protein; KEGG: sbc:SbBS512_E0910 metal-binding protein YP_003035911.1 PFAM: cytochrome B561; KEGG: sbo:SBO_1032 cytochrome YP_003035912.1 PFAM: transposase IS4 family protein; KEGG: sea:SeAg_B3181 IS10 transposase YP_003035913.1 KEGG: sdy:SDY_1034 sulfite oxidase subunit YedZ YP_003035914.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_003035915.1 KEGG: sfv:SFV_2015 hypothetical protein; TIGRFAM: hydroxyisourate hydrolase; PFAM: transthyretin; SMART: transthyretin YP_003035916.1 induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced YP_003035917.1 KEGG: ssn:SSON_2026 2-component sensor protein; TIGRFAM: heavy metal sensor kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein YP_003035918.1 Hsp31 stabilizes early unfolding protein intermediates under severe heat stress YP_003035920.1 KEGG: sbo:SBO_1045 hypothetical protein YP_003035921.1 PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: sbc:SbBS512_E0922 metal-dependent phosphohydrolase YP_003035922.1 TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase YP_003035923.1 TIGRFAM: DNA mismatch endonuclease Vsr; PFAM: DNA mismatch endonuclease vsr; KEGG: elf:LF82_2418 very short patch repair protein YP_003035924.1 TIGRFAM: carboxylate/amino acid/amine transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: elf:LF82_2949 uncharacterized inner membrane transporter YedA YP_003035925.1 PFAM: protein of unknown function DUF808; KEGG: sdy:SDY_1048 hypothetical protein YP_003035926.1 KEGG: ssn:SSON_2014 hypothetical protein YP_003035927.1 KEGG: ssn:SSON_2013 hypothetical protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein YP_003035928.1 catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate YP_003035929.1 KEGG: sdy:SDY_1052 hypothetical protein YP_003035930.1 KEGG: ssn:SSON_2010 hypothetical protein YP_003035931.1 PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: sfv:SFV_1994 positive regulator for ctr capsule biosynthesis, positive transcription factor YP_003035932.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus YP_003035933.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus YP_003035934.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_003035935.1 with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus YP_003035936.1 One of three proteins involved in switching the direction of the flagellar rotation YP_003035937.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_003035938.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring YP_003035939.1 PFAM: flagellar hook-length control protein YP_003035940.1 rod/hook and filament chaperone YP_003035941.1 involved in type III protein export during flagellum assembly YP_003035942.1 binds to and inhibits the function of flagella specific ATPase FliI YP_003035943.1 One of three proteins involved in switching the direction of the flagellar rotation YP_003035944.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_003035945.1 forms a junction between the M-ring and FlgB during flagella biosynthesis YP_003035946.1 PFAM: GCN5-related N-acetyltransferase; KEGG: efe:EFER_2671 acyltransferase YP_003035947.1 PFAM: protein of unknown function DUF159; KEGG: ssn:SSON_1987 hypothetical protein YP_003035948.1 PFAM: SirA family protein; KEGG: sea:SeAg_B1154 hypothetical protein YP_003035949.1 PFAM: protein of unknown function DUF395 YeeE/YedE YP_003035950.1 KEGG: sdy:SDY_1087 hypothetical protein YP_003035951.1 converts 1,4-alpha-D-glucans to maltodextrin YP_003035952.1 binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family YP_003035953.1 flagellin specific chaperone YP_003035954.1 involved in flagellin assembly YP_003035955.1 structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes YP_003035956.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_003035957.1 expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence YP_003035958.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; ionotropic glutamate receptor; KEGG: sfl:SF1963 cystine transporter subunit YP_003035959.1 catalyzes the formation of pyruvate from D-cysteine YP_003035960.1 TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: ssn:SSON_1200 transporter permease (former YecC) YP_003035961.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: ssn:SSON_1201 amino-acid ABC transporter ATP-binding protein YecC YP_003035962.1 regulates genes involved in cell division YP_003035963.1 KEGG: ssn:SSON_1203 hypothetical protein YP_003035965.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system YP_003035966.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_003035967.1 KEGG: sdy:SDY_1106 phosphatidylglycerophosphate synthetase; TIGRFAM: CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase YP_003035968.1 TIGRFAM: yecA family protein; PFAM: SEC-C motif domain protein; KEGG: sbo:SBO_1098 hypothetical protein YP_003035969.1 TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; Amino acid transporter transmembrane; KEGG: sfv:SFV_1951 tyrosine transporter YP_003035970.1 KEGG: sbc:SbBS512_E1032 hypothetical protein YP_003035971.1 cytoplasmic iron storage protein YP_003035972.1 KEGG: ssn:SSON_1214 hypothetical protein YP_003035973.1 KEGG: sbc:SbBS512_E1028 hypothetical protein YP_003035974.1 KEGG: sdy:SDY_1117 hypothetical protein YP_003035975.1 PFAM: ferritin; KEGG: ssn:SSON_1216 ferritin-like protein YP_003035976.1 PFAM: periplasmic binding protein/LacI transcriptional regulator YP_003035977.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_003035978.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_003035979.1 biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature YP_003035980.1 KEGG: ssn:SSON_1221 trehalose-6-phosphate synthase; TIGRFAM: alpha,alpha-trehalose-phosphate synthase [UDP-forming]; PFAM: glycosyl transferase family 20 YP_003035981.1 ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress YP_003035982.1 with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems YP_003035983.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems YP_003035984.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_003035985.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_003035986.1 chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component YP_003035987.1 PFAM: CheW domain protein; SMART: CheW domain protein; KEGG: ssn:SSON_1230 purine-binding chemotaxis protein YP_003035988.1 PFAM: chemotaxis sensory transducer; ligand binding Tar domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; ligand binding Tar domain protein; KEGG: ssn:SSON_1231 methyl-accepting chemotaxis protein II YP_003035989.1 mediates taxis toward dipeptides YP_003035990.1 methylates the MCP YP_003035991.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_003035992.1 chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble YP_003035993.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation YP_003035994.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_003035995.1 membrane protein involved in the flagellar export apparatus YP_003035996.1 PFAM: flagellar FlhE family protein; KEGG: sbc:SbBS512_E2171 flagellar protein FlhE YP_003035997.1 PFAM: protein of unknown function DUF1311; KEGG: sbo:SBO_1123 hypothetical protein YP_003035998.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_003035999.1 PFAM: protein of unknown function DUF991 YP_003036000.1 PFAM: CutC family protein; KEGG: elf:LF82_0392 copper homeostasis protein CutC YP_003036001.1 PFAM: NapC/NirT cytochrome C domain protein; KEGG: sfv:SFV_1911 cytochrome C protein YP_003036002.1 TIGRFAM: molybdopterin guanine dinucleotide-containing S/N-oxide reductase; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region YP_003036003.1 TIGRFAM: methyltransferase; PFAM: methyltransferase YP_003036004.1 TIGRFAM: methyltransferase; PFAM: methyltransferase type 12; methyltransferase type 11; KEGG: sdy:SDY_1169 hypothetical protein YP_003036005.1 KEGG: sdy:SDY_1168 hypothetical protein YP_003036006.1 PFAM: protein of unknown function DUF72 YP_003036007.1 PFAM: isochorismatase hydrolase; KEGG: elf:LF82_2940 isochorismatase family protein YecD YP_003036008.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_003036009.1 converts dATP to dAMP and pyrophosphate YP_003036010.1 PFAM: protein of unknown function DUF28; KEGG: efe:EFER_1208 hypothetical protein YP_003036011.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_003036012.1 PFAM: protein of unknown function DUF1105; KEGG: ssn:SSON_1279 hypothetical protein YP_003036013.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_003036014.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_003036015.1 involved in transport of zinc(II) with ZnuA and C YP_003036016.1 involved in transport of zinc(II) with ZnuA and C YP_003036017.1 involved in transport of zinc(II) with ZnuA and C YP_003036018.1 PFAM: peptidase M23; peptidoglycan-binding LysM; Opacity-associated protein A; Opacity-associated protein A domain protein; SMART: peptidoglycan-binding LysM; KEGG: sfx:S1932 hypothetical protein YP_003036019.1 transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA YP_003036020.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_003036021.1 Represses the expression of the zwf, eda, glp and gap YP_003036022.1 KEGG: sbc:SbBS512_E2128 hypothetical protein YP_003036023.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_003036024.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_003036025.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_003036026.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_003036027.1 PFAM: YebG family protein; KEGG: sdy:SDY_1134 DNA damage-inducible protein YebG YP_003036028.1 secreted protein; unknown function YP_003036030.1 PFAM: protein of unknown function DUF533; KEGG: ssn:SSON_1302 hypothetical protein YP_003036031.1 PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues YP_003036032.1 3'-5' exonuclease activity on single or double-strand DNA YP_003036033.1 PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: sbc:SbBS512_E2118 hydrolase, carbon-nitrogen family YP_003036034.1 PFAM: DNA polymerase II subunit beta; KEGG: sdy:SDY_1128 DNA polymerase III subunit theta YP_003036035.1 PFAM: copper resistance protein CopC; KEGG: sbc:SbBS512_E2116 copper resistance protein CopC YP_003036036.1 PFAM: copper resistance D domain protein; KEGG: sbc:SbBS512_E2115 copper resistance protein D YP_003036037.1 KEGG: sdy:SDY_1125 hypothetical protein YP_003036038.1 Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins YP_003036039.1 PFAM: protein of unknown function DUF1482; KEGG: ssn:SSON_1324 hypothetical protein YP_003036040.1 PFAM: protein of unknown function DUF1480; KEGG: sfv:SFV_1392 hypothetical protein YP_003036041.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA YP_003036042.1 PFAM: hypothetical protein; KEGG: ssn:SSON_1327 hypothetical protein YP_003036043.1 TIGRFAM: integral membrane protein, PqiA family; PFAM: paraquat-inducible protein A; KEGG: sbo:SBO_1248 hypothetical protein YP_003036044.1 PFAM: GAF domain protein; SMART: GAF domain protein; KEGG: sdy:SDY_1980 hypothetical protein YP_003036045.1 affects solute and DNA transport through an unknown mechanism YP_003036046.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 YP_003036047.1 metalloprotease YP_003036048.1 PFAM: major facilitator superfamily MFS_1; KEGG: sbc:SbBS512_E2096 transporter major facilitator family YP_003036049.1 PFAM: transcriptional regulator IclR ; regulatory protein IclR; SMART: regulatory protein IclR; KEGG: sbc:SbBS512_E2095 transcriptional regulator KdgR YP_003036050.1 KEGG: sdy:SDY_1974 hypothetical protein YP_003036051.1 KEGG: sdy:SDY_1973 hypothetical protein YP_003036052.1 KEGG: elf:LF82_2929 uncharacterized protein YebO YP_003036053.1 KEGG: sdy:SDY_1970 hypothetical protein YP_003036054.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: sed:SeD_A1478 cold shock protein CspC YP_003036055.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth YP_003036056.1 membrane protein YebN YP_003036057.1 PFAM: protein of unknown function DUF986; KEGG: ssn:SSON_1340 hypothetical protein YP_003036058.1 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel YP_003036059.1 TIGRFAM: PTS system, mannose/fructose/sorbose family, IIC subunit; PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; KEGG: sbc:SbBS512_E2084 PTS system, mannose-specific IIC component YP_003036060.1 KEGG: ssn:SSON_1343 PTS enzyme IIAB, mannose-specific; TIGRFAM: PTS system, mannose/fructose/sorbose family, IIA subunit; PTS system, mannose/fructose/sorbose family, IIB subunit; PFAM: PTS system sorbose subfamily IIB component; PTS system fructose subfamily IIA component YP_003036061.1 KEGG: stm:STM1829 cytoplasmic protein YP_003036062.1 PFAM: integral membrane protein TerC; CBS domain containing protein; transporter-associated region YP_003036063.1 PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: ssn:SSON_1345 hypothetical protein YP_003036064.1 KEGG: sbo:SBO_1270 L-serine deaminase; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain YP_003036065.1 PFAM: NUDIX hydrolase; KEGG: sdy:SDY_1719 hypothetical protein YP_003036066.1 TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: chorismate binding-like; anthranilate synthase component I domain protein; KEGG: ssn:SSON_1348 p-aminobenzoate synthetase, component I YP_003036067.1 KEGG: ssn:SSON_1349 hypothetical protein YP_003036068.1 KEGG: sfv:SFV_1419 hypothetical protein YP_003036069.1 KEGG: ssn:SSON_1352 hypothetical protein YP_003036070.1 KEGG: sbo:SBO_1280 enzyme YP_003036071.1 KEGG: sfv:SFV_1422 hypothetical protein YP_003036072.1 TIGRFAM: outer membrane lipoprotein, Slp family; KEGG: sfv:SFV_1423 outer membrane protein YP_003036073.1 Activates fatty acids by binding to coenzyme A YP_003036074.1 TIGRFAM: ribonuclease D YP_003036075.1 KEGG: sbo:SBO_1285 diogenase subunit beta YP_003036076.1 KEGG: ssn:SSON_1359 hypothetical protein YP_003036077.1 TIGRFAM: tartrate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase YP_003036078.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: sbo:SBO_1289 transcriptional regulator LysR-type YP_003036079.1 PFAM: lysine exporter (LYSE/YGGA); KEGG: ssn:SSON_1363 leucine export protein LeuE YP_003036080.1 PFAM: protein of unknown function DUF1971; KEGG: sdy:SDY_1697 hypothetical protein YP_003036081.1 PFAM: Domain of unknown function DUF1869; KEGG: ssn:SSON_1365 hypothetical protein YP_003036083.1 PFAM: transglycosylase; KEGG: sdy:SDY_1695 hypothetical protein YP_003036084.1 KEGG: sdy:SDY_1692 hypothetical protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; SMART: GGDEF domain containing protein; GAF domain protein YP_003036085.1 PFAM: protein of unknown function DUF333; KEGG: sbc:SbBS512_E2046 lipoprotein YP_003036086.1 PFAM: protein of unknown function DUF488; KEGG: ssn:SSON_1369 hypothetical protein YP_003036087.1 TIGRFAM: cyanate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_1302 amino acid/amine transport protein YP_003036088.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: sdy:SDY_1688 AraC-type regulatory protein YP_003036089.1 PFAM: protein of unknown function DUF441; KEGG: sbo:SBO_1304 hypothetical protein YP_003036090.1 PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: elf:LF82_2911 uncharacterized protein YeaK YP_003036091.1 KEGG: elf:LF82_2910 uncharacterized protein YeaJ; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein YP_003036092.1 KEGG: ssn:SSON_1377 hypothetical protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein YP_003036093.1 PFAM: protein of unknown function DUF444; KEGG: sbo:SBO_1309 hypothetical protein YP_003036094.1 PFAM: MltA-interacting MipA family protein; KEGG: ssn:SSON_1380 hypothetical protein YP_003036095.1 PFAM: aldo/keto reductase YP_003036096.1 PFAM: aldose 1-epimerase; KEGG: sfv:SFV_1435 hypothetical protein YP_003036097.1 KEGG: ssn:SSON_1384 glyceraldehyde-3-phosphate dehydrogenase A; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase YP_003036098.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress YP_003036099.1 PFAM: protein of unknown function DUF1315; KEGG: sfv:SFV_1438 hypothetical protein YP_003036100.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: elf:LF82_2898 uncharacterized zinc-type alcohol dehydrogenase-like YP_003036101.1 PFAM: major facilitator superfamily MFS_1; general substrate transporter; KEGG: sdy:SDY_1492 transporter YP_003036102.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: elf:LF82_2896 uncharacterized zinc-type alcohol dehydrogenase-like YP_003036103.1 TIGRFAM: ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II YP_003036104.1 PFAM: PfkB domain protein YP_003036105.1 PFAM: aldo/keto reductase; KEGG: sfv:SFV_1444 hypothetical protein YP_003036106.1 PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; KEGG: elf:LF82_2892 uncharacterized HTH-type transcriptional regulator YP_003036107.1 PFAM: major facilitator superfamily MFS_1; general substrate transporter; KEGG: elf:LF82_2891 inner membrane metabolite transport protein YdjE YP_003036108.1 catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide YP_003036109.1 converts asparagine to aspartate and ammonia YP_003036110.1 SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane YP_003036111.1 PFAM: nitroreductase; KEGG: sbo:SBO_1322 hypothetical protein YP_003036112.1 catalyzes the formation of selenophosphate from selenide and ATP YP_003036113.1 decatenates replicating daughter chromosomes YP_003036114.1 KEGG: sfl:SF1461 hypothetical protein YP_003036115.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_003036116.1 PFAM: protein of unknown function DUF1496; KEGG: sbc:SbBS512_E2012 hypothetical protein YP_003036117.1 PFAM: NUDIX hydrolase; KEGG: elf:LF82_1533 CTP pyrophosphohydrolase YP_003036118.1 PFAM: CDP-alcohol phosphatidyltransferase; KEGG: sfx:S1582 cytochrome oxidase YP_003036119.1 PFAM: rhodanese; SMART: Rhodanese domain protein; KEGG: sbo:SBO_1332 thiosulfate sulfur transferase YP_003036120.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: sfv:SFV_1462 ATP-binding component of a transporter YP_003036121.1 KEGG: sbc:SbBS512_E2004 ABC transporter permease protein YP_003036122.1 PFAM: extracellular solute-binding protein family 1; KEGG: ssn:SSON_1403 hypothetical protein YP_003036123.1 PFAM: carboxymuconolactone decarboxylase; KEGG: sbc:SbBS512_E2002 carboxymuconolactone decarboxylase family protein YP_003036124.1 PFAM: SNARE associated Golgi protein; KEGG: elf:LF82_2903 UPF0043 inner membrane protein YdjZ YP_003036125.1 KEGG: ssn:SSON_1406 hypothetical protein YP_003036126.1 PFAM: SNARE associated Golgi protein; KEGG: ssn:SSON_1407 hypothetical protein YP_003036127.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction YP_003036128.1 KEGG: sbc:SbBS512_E1996 hypothetical protein YP_003036129.1 catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate YP_003036130.1 TIGRFAM: arginine N-succinyltransferase; arginine/ornithine succinyltransferase subunit; PFAM: arginine N-succinyltransferase subunit beta YP_003036131.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH YP_003036132.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation YP_003036133.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism YP_003036134.1 periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP YP_003036135.1 PFAM: protein of unknown function DUF886; KEGG: sfv:SFV_1478 hypothetical protein YP_003036136.1 3' incision activity; acts with UvrC YP_003036137.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_003036138.1 osmotically-inducible lipoprotein E; activator of ntr-like gene protein YP_003036139.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_003036140.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_003036141.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_003036142.1 represses the celABCDF-ydjC operon involved in carbon uptake YP_003036143.1 PFAM: glycoside hydrolase family 4; KEGG: elf:LF82_0293 6-phospho-beta-glucosidase YP_003036144.1 PFAM: YdjC family protein; KEGG: ssn:SSON_1425 hypothetical protein YP_003036145.1 catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide YP_003036146.1 KEGG: ssn:SSON_1427 cell division modulator YP_003036147.1 KEGG: sfl:SF1498 hypothetical protein YP_003036148.1 PFAM: sodium:dicarboxylate symporter YP_003036149.1 PFAM: membrane-bound metal-dependent hydrolase; KEGG: sdy:SDY_1821 hypothetical protein YP_003036150.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate YP_003036151.1 KEGG: ssn:SSON_1431 hypothetical protein YP_003036152.1 PFAM: fructosamine kinase; aminoglycoside phosphotransferase; KEGG: sdy:SDY_1818 hypothetical protein YP_003036153.1 KEGG: ssn:SSON_1433 hypothetical protein YP_003036154.1 TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein; KEGG: ssn:SSON_1434 6-phosphofructokinase 2 YP_003036155.1 PFAM: protein of unknown function DUF481; KEGG: ssn:SSON_1435 hypothetical protein YP_003036156.1 KEGG: ssn:SSON_1436 hypothetical protein YP_003036157.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_003036158.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_003036159.1 TIGRFAM: ribosomal protein L35; PFAM: ribosomal protein L35; KEGG: sea:SeAg_B1838 50S ribosomal protein L35 YP_003036160.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_003036162.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_003036163.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_003036164.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_003036165.1 with BtuD and BtuF transports vitamin B12 into the cell YP_003036166.1 similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane YP_003036167.1 ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell YP_003036168.1 PFAM: NLP/P60 protein; KEGG: elf:LF82_1500 lipoprotein NlpC YP_003036169.1 PFAM: protein of unknown function UPF0061; KEGG: sfv:SFV_1518 hypothetical protein YP_003036170.1 KEGG: sdy:SDY_1799 hypothetical protein YP_003036171.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate YP_003036172.1 PFAM: protein of unknown function DUF299; KEGG: sdy:SDY_1797 hypothetical protein YP_003036174.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_003036175.1 acts in anaerobic beta-oxidation of fatty acids; ligase/synthase involved in anaerobic growth on fatty acids YP_003036176.1 KEGG: sbc:SbBS512_E1903 iron-sulfur cluster-binding protein YP_003036177.1 PFAM: FAD dependent oxidoreductase; monooxygenase FAD-binding; HI0933 family protein; KEGG: sfv:SFV_1525 hypothetical protein YP_003036178.1 May play a role in a redox process YP_003036179.1 YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain YP_003036180.1 PFAM: cupin; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: sbc:SbBS512_E1899 AraC family transcriptional regulator YP_003036181.1 may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain YP_003036182.1 PFAM: coenzyme A transferase; KEGG: elf:LF82_2872 uncharacterized protein YdiF YP_003036183.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis YP_003036184.1 YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate YP_003036185.1 PFAM: major facilitator superfamily MFS_1 YP_003036186.1 PFAM: Domain of unknown function DUF1870; KEGG: ssn:SSON_1466 hypothetical protein YP_003036187.1 YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function YP_003036188.1 PFAM: FAD linked oxidase; KEGG: ssn:SSON_1469 oxidase YP_003036189.1 PFAM: thioesterase superfamily protein; KEGG: ssn:SSON_1470 hypothetical protein YP_003036190.1 KEGG: sfv:SFV_1708 hypothetical protein YP_003036191.1 PFAM: SufBD protein; KEGG: sbo:SBO_1447 cysteine desulfurase activator complex subunit SufB YP_003036192.1 part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE YP_003036193.1 with SufBC activates cysteine desulfurase SufS YP_003036194.1 catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine YP_003036195.1 Acts with SufS to catalyze the formation of L-alanine from L-cysteine YP_003036196.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; peptidoglycan-binding LysM; SMART: peptidoglycan-binding LysM; KEGG: sfv:SFV_1701 hypothetical protein YP_003036197.1 PFAM: LPP repeat-containing protein; KEGG: ssn:SSON_1479 murein lipoprotein YP_003036198.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_003036199.1 KEGG: ssn:SSON_1481 hypothetical protein YP_003036200.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sbo:SBO_1458 hypothetical protein YP_003036201.1 PFAM: aldehyde ferredoxin oxidoreductase ; aldehyde ferredoxin oxidoreductase; SMART: aldehyde ferredoxin oxidoreductase YP_003036202.1 KEGG: sbo:SBO_1460 hypothetical protein YP_003036203.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sfv:SFV_1693 oxidoreductase, Fe-S subunit YP_003036204.1 PFAM: cytochrome B561; KEGG: sbc:SbBS512_E1870 nickel-dependent hydrogenase, b-type cytochrome subunit YP_003036205.1 KEGG: sdy:SDY_1897 hypothetical protein YP_003036206.1 KEGG: ssn:SSON_1488 hypothetical protein YP_003036207.1 PFAM: mono-oxygenase ydhR; KEGG: sbc:SbBS512_E1865 YdhR protein YP_003036208.1 KEGG: ssn:SSON_1492 hypothetical protein YP_003036209.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones YP_003036210.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_003036211.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge YP_003036212.1 uncharacterized member of the major facilitator superfamily (MFS) YP_003036213.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: sdy:SDY_1885 DNA-binding transcriptional regulator YP_003036214.1 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers YP_003036215.1 PFAM: major facilitator superfamily MFS_1; KEGG: sdy:SDY_1883 transporter YP_003036216.1 SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals YP_003036217.1 PFAM: NLP/P60 protein; KEGG: sbc:SbBS512_E1852 NlpC/P60 family protein YP_003036218.1 TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: sdy:SDY_1880 hypothetical protein YP_003036219.1 similar to the DNA and RNA helicase superfamily II and eukaryotic DEAD family of helicases; longest known protein in E. coli YP_003036220.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) YP_003036221.1 Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione YP_003036222.1 FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide YP_003036223.1 PFAM: regulatory protein TetR; KEGG: sbc:SbBS512_E1841 TetR family transcriptional regulator YP_003036224.1 PFAM: protein of unknown function DUF1289; KEGG: sdy:SDY_1873 hypothetical protein YP_003036225.1 PFAM: aldo/keto reductase; KEGG: efe:EFER_1396 oxidoreductase YP_003036226.1 SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water YP_003036227.1 PFAM: fusaric acid resistance protein conserved region YP_003036228.1 PFAM: secretion protein HlyD; KEGG: sbc:SbBS512_E1836 auxiliary transporter, membrane fusion protein (MFP) family YP_003036229.1 PFAM: protein of unknown function DUF1656; KEGG: sfl:SF1670 hypothetical protein YP_003036230.1 transcription regulator that can both activate or repress expression YP_003036231.1 PFAM: 17 kDa surface antigen; KEGG: sfl:SF1668 outer membrane protein YP_003036232.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_003036233.1 MliC; membrane-bound lysozyme inhibitor of c-type lysozyme YP_003036234.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate YP_003036235.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_003036236.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal YP_003036237.1 PFAM: glutathione S-transferase domain; KEGG: sdy:SDY_1858 glutathionine S-transferase YP_003036238.1 mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation YP_003036239.1 KEGG: sbc:SbBS512_E1823 hypothetical protein YP_003036240.1 DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines YP_003036241.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase YP_003036242.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen YP_003036243.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents YP_003036244.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_003036245.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_003036246.1 TIGRFAM: electron transport complex, RnfABCDGE type, A subunit; PFAM: RnfA-Nqr electron transport subunit; KEGG: sbc:SbBS512_E1816 electron transport complex, RnfABCDGE type, subunit alpha YP_003036247.1 KEGG: ssn:SSON_1532 hypothetical protein YP_003036248.1 YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes YP_003036249.1 KEGG: ses:SARI_01519 hypothetical protein YP_003036250.1 PFAM: oxidoreductase domain protein; semialdehyde dehydrogenase NAD - binding; oxidoreductase domain; KEGG: sbo:SBO_1510 oxidoreductase YP_003036251.1 catalyzes the formation of inosine from adenosine YP_003036252.1 PFAM: aminotransferase class I and II; KEGG: elf:LF82_1268 protein MalY YP_003036253.1 phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS); catalyzes the phosphorylation of maltose and glucose concomitant with their translocation across the cell membrane; component IIB catalyzes the phosphorylation of the sugar molecule; IIC forms the translocation channel and contains the substrate specific binding site YP_003036254.1 regulates malXY which are involved in maltose-glucose transport YP_003036255.1 Acts on the hydroxyl group at position 7 of the steroid frame YP_003036256.1 PFAM: regulatory protein TetR; KEGG: sdy:SDY_1837 repressor for uid operon YP_003036257.1 PFAM: glycoside hydrolase family 2 TIM barrel; glycoside hydrolase family 2 sugar binding; glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; KEGG: ssn:SSON_1543 beta-D-glucuronidase YP_003036258.1 TIGRFAM: sugar (glycoside-Pentoside-Hexuronide) transporter; PFAM: major facilitator superfamily MFS_1; KEGG: ssn:SSON_1544 glucuronide transporter YP_003036259.1 PFAM: outer membrane porin; KEGG: elf:LF82_2370 membrane-associated protein UidC YP_003036261.1 PFAM: protein of unknown function DUF945; KEGG: sbc:SbBS512_E1800 hypothetical protein YP_003036262.1 KEGG: sfv:SFV_1629 mannose-6-phosphate isomerase; TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I YP_003036263.1 TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily subunit beta; hydro-lyase, Fe-S type, tartrate/fumarate subfamily, subunit alpha; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; Fe-S type hydro-lyase tartrate/fumarate beta region; KEGG: elf:LF82_0776 fumarate hydratase class I, aerobic YP_003036264.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_003036265.1 binds to DNA replication terminator sequences to prevent passage of replication forks YP_003036266.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: sdy:SDY_1825 sensor protein RstB YP_003036267.1 response regulator in two-component regulatory system with RstB YP_003036268.1 PFAM: GlpM family protein; KEGG: sdy:SDY_1546 hypothetical protein YP_003036269.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sdy:SDY_1547 short chain dehydrogenase YP_003036270.1 TIGRFAM: arginine/ornithine antiporter; PFAM: amino acid permease-associated region; KEGG: sfv:SFV_1620 arginine/ornithine antiporter YP_003036271.1 PFAM: protein of unknown function DUF1471; KEGG: elf:LF82_2844 protein YdgH YP_003036272.1 forms a tetramer composed of 2 subunit alphas and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm YP_003036273.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 subunit betas; AB-stereospecific enzyme YP_003036274.1 transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes YP_003036275.1 with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS YP_003036276.1 with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS YP_003036277.1 PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: elf:LF82_2843 uncharacterized serine protease YdgD YP_003036278.1 required for growth and survival under moderately acid conditions YP_003036279.1 PFAM: major facilitator superfamily MFS_1; KEGG: ssn:SSON_1568 transporter YP_003036280.1 PFAM: LysR substrate-binding; regulatory protein LysR YP_003036281.1 PFAM: ROK family protein; KEGG: sbc:SbBS512_E1780 transcriptional regulator Mic YP_003036282.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_003036283.1 PFAM: chloride channel core YP_003036284.1 binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane YP_003036285.1 PFAM: DMSO reductase anchor subunit (DmsC); KEGG: sbo:SBO_1546 DMSO reductase anchor subunit YP_003036286.1 TIGRFAM: dimethylsulfoxide reductase, chain B; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sdy:SDY_1567 oxidoreductase, Fe-S subunit YP_003036287.1 TIGRFAM: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; KEGG: sbo:SBO_1548 oxidoreductase, major subunit YP_003036288.1 TIGRFAM: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region YP_003036289.1 PFAM: protein of unknown function DUF1161 YP_003036290.1 PFAM: protein of unknown function UPF0257; KEGG: sfv:SFV_1559 hypothetical protein YP_003036291.1 PFAM: GCN5-related N-acetyltransferase YP_003036292.1 PFAM: protein of unknown function DUF1283; KEGG: sfv:SFV_1561 hypothetical protein YP_003036293.1 PFAM: protein of unknown function UPF0060; KEGG: elf:LF82_3567 UPF0060 membrane protein YnfA YP_003036294.1 PFAM: mandelate racemase/muconate lactonizing protein YP_003036295.1 PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: elf:LF82_2029 starvation-sensing protein RspB YP_003036296.1 KEGG: elf:LF82_2828 ExoO exonuclease VIII, ds DNA exonuclease encoded by prophage CP-933O YP_003036297.1 PFAM: protein of unknown function DUF1482; KEGG: elf:LF82_2827 uncharacterized protein YdfD YP_003036298.1 PFAM: DicB family protein; KEGG: elf:LF82_0484 division inhibition protein DicB YP_003036301.1 The transcriptional repressor of DicA (divison cell) has a hypothetical DNA binding domain. It represses the transcription of dicB and dicC, but its specific role in cellular replication and mode of action are still unknown. YP_003036303.1 PFAM: protein of unknown function DUF1019 YP_003036304.1 KEGG: sbc:SbBS512_E1433 phage O protein family YP_003036305.1 PFAM: protein of unknown function DUF977; KEGG: sbc:SbBS512_E1436 hypothetical protein YP_003036306.1 PFAM: Hok/gef cell toxic protein; KEGG: sfx:S2143 cell killing protein of prophage YP_003036307.1 KEGG: sfv:SFV_1543 hypothetical protein YP_003036308.1 KEGG: elf:LF82_p279 hypothetical protein YP_003036309.1 PFAM: protein of unknown function DUF1277; SMART: HNH nuclease; KEGG: elf:LF82_2839 uncharacterized protein YdfU YP_003036310.1 PFAM: antitermination Q family protein; KEGG: efe:EFER_2706 antitermination protein Q homolog; DLP12 prophage YP_003036311.1 lipocalin; globomycin-sensitive outer membrane lipoprotein YP_003036312.1 KEGG: efe:EFER_2704 conserved hypothetical protein from bacteriophage origin YP_003036313.1 PFAM: Integrase catalytic region; KEGG: sfv:SFV_1039 IS3 ORF2 YP_003036314.1 PFAM: transposase IS3/IS911 family protein; KEGG: sfx:S3209 IS3 orfA YP_003036315.1 KEGG: elf:LF82_p182 hypothetical protein YP_003036317.1 KEGG: elf:LF82_p259 hypothetical protein YP_003036318.1 PFAM: Resolvase domain; Resolvase helix-turn-helix domain protein; KEGG: elf:LF82_1666 DNA-invertase from lambdoid prophage Rac YP_003036319.1 KEGG: elf:LF82_2833 uncharacterized protein YdfK YP_003036320.1 TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: major facilitator superfamily MFS_1; general substrate transporter; KEGG: elf:LF82_2832 inner membrane metabolite transport protein YdfJ YP_003036321.1 PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: sfx:S1678 oxidoreductase YP_003036322.1 TIGRFAM: selenium-binding protein YdfZ; KEGG: sdy:SDY_1584 hypothetical protein YP_003036323.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: ssn:SSON_1588 hypothetical protein YP_003036324.1 NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine YP_003036325.1 PFAM: peptidase M3A and M3B thimet/oligopeptidase F YP_003036326.1 PFAM: damage inducible protein CinA; KEGG: sdy:SDY_1588 competence damage-inducible protein A YP_003036327.1 PFAM: conserved hypothetical protein; KEGG: sbc:SbBS512_E1704 hypothetical protein YP_003036328.1 KEGG: elf:LF82_2817 uncharacterized protein YdeH; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein YP_003036329.1 KEGG: sea:SeAg_B1655 hypothetical protein YP_003036330.1 YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters YP_003036331.1 PFAM: protein of unknown function DUF6 transmembrane; protein of unknown function DUF250; KEGG: sfv:SFV_1593 O-acetylserine/cysteine export protein YP_003036332.1 KEGG: ssn:SSON_1596 hypothetical protein YP_003036333.1 transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF YP_003036334.1 Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes YP_003036335.1 PFAM: protein of unknown function DUF891; KEGG: esa:ESA_03838 hypothetical protein YP_003036336.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: plu:plu0900 hypothetical protein YP_003036337.1 protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function YP_003036338.1 PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_1646 sugar efflux transporter YP_003036339.1 KEGG: ssn:SSON_1601 hypothetical protein YP_003036340.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: elf:LF82_3566 uncharacterized HTH-type transcriptional regulator YP_003036341.1 in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase YP_003036342.1 catalyzes the formation of glutamate from glutamine YP_003036343.1 KEGG: sfv:SFV_1582 hypothetical protein YP_003036344.1 KEGG: sfv:SFV_1581 hypothetical protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein YP_003036345.1 catalyzes the formation of D-tagaturonate from D-altronate YP_003036346.1 PFAM: protein of unknown function UPF0187; KEGG: sbc:SbBS512_E1689 hypothetical protein YP_003036347.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate YP_003036348.1 PFAM: antibiotic biosynthesis monooxygenase; KEGG: sdy:SDY_1624 autoinducer-2 (AI-2) modifying protein LsrG YP_003036349.1 PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: efe:EFER_1560 aldolase YP_003036351.1 TIGRFAM: outer membrane autotransporter barrel domain protein; PFAM: Autotransporter beta- domain protein; Pertactin YP_003036353.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: ssn:SSON_1613 DNA-binding transcriptional regulator YP_003036354.1 TIGRFAM: HipA N-terminal domain protein; PFAM: HipA domain protein; KEGG: elf:LF82_0996 protein HipA YP_003036355.1 PFAM: fimbrial protein; KEGG: elf:LF82_p244 Fml fimbriae subunit YP_003036356.1 PFAM: fimbrial protein YP_003036357.1 PFAM: fimbrial protein YP_003036358.1 PFAM: FimH mannose-binding domain protein; fimbrial protein; KEGG: ssn:SSON_1621 adhesin YP_003036359.1 in Escherichia coli it may be involved in repression of type III secretion system (TTSS) genes of the host cell; involved with increased resistance to low pH; member of the prokaryotic molybdopterin-containing oxidoreductase family YP_003036360.1 KEGG: sfx:S1655 hypothetical protein YP_003036361.1 regulates the cellular response to acid resistance YP_003036362.1 PFAM: sulfatase YP_003036363.1 PFAM: radical SAM protein; KEGG: sfv:SFV_1723 enzyme YP_003036364.1 PFAM: ABC transporter; ABC transporter domain protein; SbmABacA family protein; SMART: ATPase AAA; KEGG: ssn:SSON_1627 ATP-binding component of a transporter YP_003036365.1 PFAM: TonB-dependent receptor plug; TonB-dependent receptor; KEGG: ssn:SSON_1629 hypothetical protein YP_003036366.1 PFAM: peptidase M16 domain protein; KEGG: sbo:SBO_1562 peptidase YP_003036367.1 TIGRFAM: glutamate decarboxylase; PFAM: pyridoxal-dependent decarboxylase; KEGG: sbo:SBO_1563 glutamate decarboxylase isozyme YP_003036368.1 TIGRFAM: glutamate/g-aminobutyrate antiporter; PFAM: amino acid permease-associated region; KEGG: sbc:SbBS512_E1755 glutamate:gamma aminobutyrate antiporter YP_003036369.1 PFAM: protein of unknown function DUF187; KEGG: ssn:SSON_1633 hypothetical protein YP_003036370.1 KEGG: ssn:SSON_1634 hypothetical protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein YP_003036371.1 heme-regulated phosphodiesterase with phosphodiesterase activity with cAMP but not with cGMP, bis(p-nitrophenyl) phosphate or p-nitrophenyl phosphate YP_003036372.1 catalyzes the hydrolysis of D-alanyl-D-alanine dipeptide: Zn dependent; involved in peptidoglycan synthesis YP_003036373.1 PFAM: extracellular solute-binding protein family 5 YP_003036374.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: sbo:SBO_1571 transporter permease protein YP_003036375.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: ssn:SSON_1639 ATP-dependent peptide transporter membrane subunit YP_003036376.1 KEGG: sbc:SbBS512_E1747 ABC transporter ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA YP_003036377.1 KEGG: sbo:SBO_1574 ATP-binding component of a transporter; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase subunit; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA YP_003036378.1 PFAM: OsmC family protein; KEGG: sfv:SFV_1739 osmotically inducible protein YP_003036379.1 KEGG: efe:EFER_1498 biofilm-dependent modulation protein YP_003036380.1 protein D; stationary-phase-induced ribosome-associated; in Escherichia coli this protein becomes associated with the ribosome; expression increases during stationary phase YP_003036381.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_003036382.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs YP_003036383.1 KEGG: ssn:SSON_1647 hypothetical protein; TIGRFAM: addiction module antidote protein, HigA family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein YP_003036384.1 nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase YP_003036385.1 TIGRFAM: formate dehydrogenase subunit beta; PFAM: formate dehydrogenase transmembrane domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sfv:SFV_1746 formate dehydrogenase-N, nitrate-inducible, iron-sulfur subunit beta YP_003036386.1 KEGG: ssn:SSON_1650 formate dehydrogenase-N, nitrate-inducible, subunit alpha; TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region YP_003036387.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: elf:LF82_2811 inner membrane protein YddG YP_003036388.1 KEGG: sbo:SBO_1585 outer membrane porin protein YP_003036389.1 TIGRFAM: nitrite transporter; PFAM: major facilitator superfamily MFS_1; KEGG: elf:LF82_1467 nitrite extrusion protein 2 YP_003036390.1 TIGRFAM: nitrate reductase, subunit alpha; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: sfv:SFV_1757 cryptic nitrate reductase 2, subunit alpha YP_003036391.1 TIGRFAM: nitrate reductase subunit beta YP_003036392.1 KEGG: ssn:SSON_1659 cryptic nitrate reductase 2, delta subunit, assembly function; TIGRFAM: nitrate reductase molybdenum cofactor assembly chaperone; PFAM: nitrate reductase subunit delta YP_003036393.1 TIGRFAM: respiratory nitrate reductase, gamma subunit; PFAM: nitrate reductase subunit gamma YP_003036394.1 PFAM: N-acetyltransferase; KEGG: ssn:SSON_1662 N-hydroxyarylamine O-acetyltransferase YP_003036395.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: elf:LF82_2812 uncharacterized protein YddH YP_003036396.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown YP_003036397.1 PFAM: transposase IS4 family protein; KEGG: ssn:SSON_0260 receptor YP_003036399.1 KEGG: ssn:SSON_0520 Vgr protein YP_003036400.1 KEGG: sdy:SDY_1950 hypothetical protein YP_003036401.1 KEGG: sbo:SBO_1593 transferase YP_003036402.1 KEGG: sbc:SbBS512_E1726 hypothetical protein YP_003036403.1 PFAM: amino acid permease-associated region; KEGG: sbc:SbBS512_E1725 L-asparagine permease YP_003036404.1 KEGG: sbc:SbBS512_E1724 hypothetical protein YP_003036405.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: ssn:SSON_1682 outer membrane receptor for iron transport YP_003036406.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; KEGG: sfv:SFV_1761 DNA-binding transcriptional regulator YP_003036407.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; KEGG: sfv:SFV_1762 oxidoreductase YP_003036408.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sbc:SbBS512_E1718 acetyltransferase, GNAT family YP_003036409.1 PFAM: protein of unknown function DUF606; KEGG: sbo:SBO_1601 hypothetical protein YP_003036410.1 KEGG: sfl:SF1771 hypothetical protein YP_003036411.1 KEGG: sdy:SDY_1729 hypothetical protein YP_003036412.1 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation YP_003036413.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: sfv:SFV_1771 transporter permease protein YP_003036414.1 PFAM: binding-protein-dependent transporters inner membrane component YP_003036415.1 PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; KEGG: ssn:SSON_1696 ATP-binding component of a transporter YP_003036416.1 PFAM: extracellular solute-binding protein family 1; KEGG: ssn:SSON_1697 transporter YP_003036417.1 PFAM: regulatory protein GntR HTH; aminotransferase class I and II; SMART: regulatory protein GntR HTH; KEGG: ssn:SSON_1698 multi modular; transcriptional regulator; also ATP-binding component of a transporter YP_003036418.1 PFAM: protein of unknown function UPF0150; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: sdy:SDY_1736 hypothetical protein YP_003036419.1 PFAM: YcfA family protein; KEGG: cko:CKO_01475 hypothetical protein YP_003036420.1 KEGG: ssn:SSON_1702 hypothetical protein YP_003036421.1 PFAM: peptidase U32 YP_003036422.1 PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; SMART: helix-turn-helix domain protein; KEGG: ssn:SSON_1704 hypothetical protein YP_003036423.1 TIGRFAM: benzoate transporter; PFAM: Benzoate membrane transporter; xanthine/uracil/vitamin C permease YP_003036424.1 TIGRFAM: transposase, IS605 OrfB family; PFAM: transposase IS891/IS1136/IS1341 family; transposase IS605 OrfB; KEGG: ssn:SSON_1709 virulence protein YP_003036425.1 KEGG: elf:LF82_2797 uncharacterized lipoprotein YdcL YP_003036426.1 with TehA confers resistance to tellurite YP_003036427.1 TIGRFAM: C4-dicarboxylate transporter/malic acid transporter; PFAM: C4-dicarboxylate transporter/malic acid transport protein; KEGG: sfv:SFV_1777 potassium-tellurite ethidium and proflavin transporter YP_003036429.1 PFAM: GCN5-related N-acetyltransferase; KEGG: elf:LF82_1889 ribosomal-protein-serine acetyltransferase YP_003036430.1 PFAM: protein of unknown function DUF465; KEGG: sfv:SFV_1780 hypothetical protein YP_003036431.1 involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans YP_003036432.1 PFAM: protein of unknown function DUF1338; KEGG: ssn:SSON_1719 hypothetical protein YP_003036433.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: ssn:SSON_1720 transcriptional regulator LysR-type YP_003036434.1 PFAM: chemotaxis sensory transducer; ligand binding Tar domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; ligand binding Tar domain protein; KEGG: sfx:S1485 methyl-accepting chemotaxis protein III, ribose sensor receptor YP_003036435.1 KEGG: ssn:SSON_1722 hypothetical protein YP_003036436.1 KEGG: ssn:SSON_1723 hypothetical protein YP_003036437.1 B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm YP_003036438.1 PFAM: IS1 transposase; KEGG: sty:HCM1.136a IS1 transposase YP_003036439.1 PFAM: Insertion element protein; KEGG: dps:DP0861 insertion element iso-IS1d protein (InsA) YP_003036440.1 KEGG: ssn:SSON_1725 glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase; PFAM: glyceraldehyde 3-phosphate dehydrogenase YP_003036441.1 NAD-linked YP_003036442.1 PFAM: protein of unknown function DUF218 YP_003036443.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain YP_003036444.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_003036445.1 PFAM: Dual specificity protein phosphatase; phosphoesterase PA-phosphatase related; SMART: Dual specificity protein phosphatase; protein-tyrosine phosphatase, catalytic; KEGG: sbc:SbBS512_E1631 PAP2 family protein YP_003036446.1 KEGG: sdy:SDY_1779 hypothetical protein YP_003036447.1 PFAM: phosphatidate cytidylyltransferase; KEGG: elf:LF82_3553 uncharacterized protein YnbB YP_003036448.1 PFAM: CDP-alcohol phosphatidyltransferase; KEGG: efe:EFER_1593 conserved hypothetical protein; inner membrane protein YP_003036450.1 PFAM: Integrase catalytic region; KEGG: seh:SeHA_C4704 ISEc16, orfB YP_003036451.1 PFAM: transposase IS3/IS911 family protein YP_003036452.1 PFAM: aldehyde dehydrogenase; KEGG: efe:EFER_1612 phenylacetaldehyde dehydrogenase YP_003036453.1 activator of genes involved in phenylacetic acid catabolism YP_003036454.1 PFAM: conserved hypothetical protein; KEGG: sbo:SBO_1683 hypothetical protein YP_003036455.1 KEGG: ssn:SSON_1742 hypothetical protein YP_003036456.1 KEGG: sbo:SBO_1685 hypothetical protein YP_003036457.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; KEGG: sbc:SbBS512_E1618 D-lactate dehydrogenase YP_003036458.1 PFAM: protein of unknown function DUF306 Meta and HslJ; KEGG: ssn:SSON_1745 heat-inducible protein YP_003036459.1 KEGG: ssn:SSON_1746 cytoplasmic protein YP_003036460.1 TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein YP_003036461.1 PFAM: porin Gram-negative type; KEGG: sbc:SbBS512_E1614 outer membrane protein N YP_003036462.1 PFAM: UspA domain protein; KEGG: ssn:SSON_1749 filament protein YP_003036463.1 KEGG: elf:LF82_2833 uncharacterized protein YdfK YP_003036464.1 PFAM: Resolvase domain; Resolvase helix-turn-helix domain protein; KEGG: elf:LF82_1666 DNA-invertase from lambdoid prophage Rac YP_003036465.1 KEGG: elf:LF82_p183 hypothetical protein YP_003036466.1 KEGG: elf:LF82_p182 hypothetical protein YP_003036467.1 KEGG: elf:LF82_p261 hypothetical protein YP_003036468.1 PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; KEGG: ypi:YpsIP31758_2231 ParB family protein YP_003036469.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: efe:EFER_1950 trk system potassium uptake protein YP_003036470.1 PFAM: lysis protein; KEGG: elf:LF82_2080 Rz endopeptidase from lambdoid prophage DLP12 YP_003036471.1 PFAM: glycoside hydrolase family 24; KEGG: sbc:SbBS512_E1450 phage lysozyme YP_003036472.1 KEGG: sbc:SbBS512_E0946 hypothetical protein YP_003036473.1 PFAM: protein of unknown function DUF1327; KEGG: sbc:SbBS512_E0945 hypothetical protein YP_003036474.1 PFAM: Lysis S family protein; KEGG: elf:LF82_0578 lysis protein S homolog from lambdoid prophage DLP12 YP_003036476.1 PFAM: protein of unknown function DUF1391; KEGG: sbc:SbBS512_E0694 hypothetical protein YP_003036477.1 KEGG: set:SEN1382 phage membrane protein YP_003036478.1 Rac prophage Kil protein; Kil overexpression leads to morphological defects and inhibits cell division YP_003036479.1 KEGG: sty:STY2071 bacteriophage protein YP_003036480.1 Rac prophage hypothetical protein YP_003036481.1 TIGRFAM: RecT protein; PFAM: RecT protein; KEGG: spq:SPAB_02270 recombination and repair protein RecT YP_003036482.1 Rac prophage YP_003036483.1 PFAM: protein of unknown function DUF1233 excisionase KEGG: sfl:SF1369 hypothetical protein YP_003036484.1 PFAM: integrase; KEGG: sbo:SBO_1716 transposase YP_003036485.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_003036486.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA YP_003036487.1 KEGG: efe:EFER_1627 hypothetical protein YP_003036488.1 PFAM: Mg2 transporter protein CorA family protein; KEGG: sdy:SDY_1424 zinc transporter YP_003036489.1 KEGG: sbo:SBO_1720 hypothetical protein; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain containing protein; hypothetical protein; SMART: GGDEF domain containing protein; PAS domain containing protein YP_003036490.1 PFAM: Smr protein/MutS2; SMART: Smr protein/MutS2; KEGG: elf:LF82_2783 uncharacterized protein ydal YP_003036491.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: ssn:SSON_1792 DNA-binding transcriptional regulator YP_003036492.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: ssn:SSON_1793 aminohydrolase YP_003036493.1 TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: ssn:SSON_1794 hypothetical protein YP_003036494.1 TIGRFAM: AbgT transporter family; PFAM: AbgT transporter YP_003036495.1 KEGG: ssn:SSON_1798 O-6-alkylguanine-DNA:cysteine-protein methyltransferase; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; methylguanine DNA methyltransferase ribonuclease domain protein YP_003036496.1 with UspC and UspD is involved in resistance to UV irradiation YP_003036497.1 KEGG: ssn:SSON_1801 hypothetical protein YP_003036498.1 PFAM: MscS Mechanosensitive ion channel; KEGG: sbc:SbBS512_E1570 transporter small conductance mechanosensitive ion channel family YP_003036499.1 PFAM: extracellular solute-binding protein family 5; KEGG: ssn:SSON_1804 transport periplasmic protein YP_003036500.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: sbo:SBO_1734 transcriptional regulator LysR-type YP_003036501.1 KEGG: ssn:SSON_1806 hypothetical protein YP_003036502.1 KEGG: ssn:SSON_1810 hypothetical protein YP_003036503.1 PFAM: peptidase M14 carboxypeptidase A; KEGG: ssn:SSON_1812 murein peptide amidase A YP_003036504.1 PFAM: mandelate racemase/muconate lactonizing protein; KEGG: sfv:SFV_1341 muconate cycloisomerase I YP_003036505.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein YP_003036506.1 regulates genes involved in the biosynthesis and transport of aromatic amino acids YP_003036507.1 PFAM: conserved hypothetical protein; KEGG: elf:LF82_2767 UPF0283 membrane protein YcjF YP_003036508.1 PFAM: protein of unknown function DUF463 YcjX family protein; KEGG: sbc:SbBS512_E1554 hypothetical protein YP_003036509.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; KEGG: sbc:SbBS512_E1553 LacI family transcriptional regulator YP_003036511.1 PFAM: ABC transporter; TOBE domain protein; transport-associated OB domain protein; SMART: ATPase AAA YP_003036512.1 TIGRFAM: beta-phosphoglucomutase; beta-phosphoglucomutase family hydrolase; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase YP_003036513.1 PFAM: glycoside hydrolase family 65 central catalytic; glycoside hydrolase family 65 domain protein; KEGG: ssn:SSON_1824 hypothetical protein YP_003036514.1 PFAM: oxidoreductase domain protein; oxidoreductase domain; KEGG: elf:LF82_2775 oxidoreductase YcjS YP_003036515.1 PFAM: xylose isomerase; KEGG: elf:LF82_2774 uncharacterized protein YcjR YP_003036516.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; KEGG: sfv:SFV_1329 oxidoreductase YP_003036517.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: sfv:SFV_1328 transporter permease protein YP_003036518.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: ssn:SSON_1829 binding-protein dependent transporter YP_003036519.1 PFAM: extracellular solute-binding protein family 1 YP_003036520.1 PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain YP_003036521.1 rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide YP_003036522.1 TIGRFAM: phage shock protein PspD; KEGG: ssn:SSON_1833 peripheral inner membrane phage-shock protein YP_003036523.1 with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock YP_003036524.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding YP_003036525.1 involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF YP_003036526.1 transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor YP_003036527.1 putrescine-inducible GABA aminotransferase; catalyzes the formation of glutamate and succinate semialdehyde from 4-aminobutyrate and 2-oxoglutarate YP_003036528.1 PFAM: FAD dependent oxidoreductase YP_003036529.1 catalyzes the formation of gamma-glutamyl-gamma-aminobutyrate from gamma-glutamyl-gamma-aminobutyraldehyde; involved in putrescine degradation YP_003036530.1 regulates genes involved in putrescine degradation YP_003036531.1 catalyzes the degradation of gamma-glutamyl-gamma-aminobutyrate into glutamate and gamma-aminobutyrate YP_003036532.1 PFAM: glutamine synthetase YP_003036533.1 PFAM: amino acid permease-associated region; KEGG: ssn:SSON_1844 amino acid/amine transporter YP_003036534.1 KEGG: sdy:SDY_1637 hypothetical protein YP_003036535.1 PFAM: extracellular solute-binding protein family 5; KEGG: ssn:SSON_1846 peptide transport periplasmic protein-like protein YP_003036536.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: sbc:SbBS512_E1529 peptide ABC transporter permease protein SapB YP_003036537.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: sbc:SbBS512_E1528 peptide ABC transporter permease protein SapC YP_003036538.1 KEGG: sbc:SbBS512_E1527 peptide ABC transporter ATP-binding protein SapD; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA YP_003036539.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: sbc:SbBS512_E1526 peptide ABC transporter ATP-binding protein SapF YP_003036540.1 PFAM: protein of unknown function DUF559; KEGG: sbo:SBO_1773 hypothetical protein YP_003036541.1 Catalyzes a key regulatory step in fatty acid biosynthesis YP_003036542.1 KEGG: sbc:SbBS512_E1521 hypothetical protein YP_003036543.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction YP_003036545.1 c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP YP_003036546.1 KEGG: sdy:SDY_1362 hypothetical protein YP_003036547.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; SMART: regulatory protein DeoR; KEGG: ssn:SSON_1856 DeoR-type transcriptional regulator YP_003036548.1 KEGG: ssn:SSON_1857 lipoprotein YP_003036549.1 involved in start site selection during the initiation of translation YP_003036550.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_003036551.1 SMART: hypothetical protein; KEGG: ssn:SSON_1860 hypothetical protein YP_003036552.1 PFAM: protein of unknown function DUF1049; KEGG: sfv:SFV_1292 hypothetical protein YP_003036553.1 KEGG: sdy:SDY_1354 phosphatidylglycerophosphatase B; PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related YP_003036554.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate YP_003036555.1 Catalyzes the conversion of citrate to isocitrate YP_003036557.1 KEGG: sbc:SbBS512_E1503 hypothetical protein YP_003036558.1 KEGG: sdy:SDY_1348 hypothetical protein YP_003036559.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation YP_003036560.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_003036561.1 KEGG: hypothetical protein YP_003036562.1 SohB; periplasmic protein; member of the peptidase S49 family YP_003036563.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: ssn:SSON_1872 short chain dehydrogenase YP_003036564.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide YP_003036565.1 catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA YP_003036566.1 PFAM: IS1 transposase; KEGG: sty:HCM1.136a IS1 transposase YP_003036567.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; KEGG: sbc:SbBS512_E1491 SUA5/YciO/YrdC/YwlC family protein YP_003036568.1 PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: elf:LF82_2314 protein TrpH YP_003036569.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_003036570.1 bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis YP_003036571.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate YP_003036572.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_003036573.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_003036574.1 KEGG: sfv:SFV_1273 hypothetical protein YP_003036575.1 PFAM: protein of unknown function DUF892; KEGG: elf:LF82_2752 protein YciF YP_003036576.1 PFAM: protein of unknown function DUF892 YP_003036577.1 receptor for colicin S4 YP_003036578.1 PFAM: protein of unknown function UPF0259; KEGG: ssn:SSON_1911 hypothetical protein YP_003036579.1 Involved in cell division; probably involved in intracellular septation YP_003036580.1 YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins YP_003036581.1 membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins YP_003036582.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity YP_003036583.1 PFAM: TrkA-N domain protein; ion transport 2 domain protein; KEGG: elf:LF82_1141 potassium channel protein YP_003036584.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) YP_003036585.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein YP_003036586.1 KEGG: sfv:SFV_1259 ATP-binding protein of oligopeptide ABC transporter; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase subunit; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA YP_003036587.1 KEGG: sbc:SbBS512_E1415 oligopeptide ABC transporter ATP-binding protein OppD; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA YP_003036588.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: ssn:SSON_1935 oligopeptide transport permease protein-like protein YP_003036589.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: sbo:SBO_1823 oligopeptide transporter permease YP_003036590.1 PFAM: extracellular solute-binding protein family 5; KEGG: sbo:SBO_1824 oligopeptide transport periplasmic binding protein YP_003036591.1 KEGG: elf:LF82_p209 hypothetical protein YP_003036593.1 PFAM: multiple antibiotic resistance (MarC)-related protein; KEGG: ssn:SSON_1938 hypothetical protein YP_003036594.1 PFAM: iron-containing alcohol dehydrogenase; aldehyde dehydrogenase; KEGG: ssn:SSON_1939 CoA-linked acetaldehyde dehydrogenase and iron-dependent alcohol dehydrogenase; pyruvate-formate-lyase deactivase YP_003036595.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_003036596.1 PFAM: histone family protein nucleoid-structuring protein H-NS; SMART: histone family protein nucleoid-structuring protein H-NS; KEGG: ssn:SSON_1942 global DNA-binding transcriptional dual regulator H-NS YP_003036597.1 together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose YP_003036598.1 PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: sdy:SDY_1287 response regulator of RpoS YP_003036599.1 PFAM: patatin; KEGG: ssn:SSON_1945 hypothetical protein YP_003036600.1 PFAM: SEC-C motif domain protein; KEGG: sbc:SbBS512_E1398 sec-C motif domain protein YP_003036601.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_003036602.1 KEGG: sbc:SbBS512_E1395 respiratory nitrate reductase 1, subunit gamma; TIGRFAM: respiratory nitrate reductase, subunit gamma; PFAM: nitrate reductase subunit gamma YP_003036603.1 KEGG: sbc:SbBS512_E1394 nitrate reductase molybdenum cofactor assembly chaperone 1; TIGRFAM: nitrate reductase molybdenum cofactor assembly chaperone; PFAM: nitrate reductase subunit delta YP_003036604.1 TIGRFAM: nitrate reductase subunit beta; KEGG: sbo:SBO_1841 nitrate reductase 1 subunit beta YP_003036605.1 TIGRFAM: nitrate reductase, subunit alpha; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: sfv:SFV_1240 nitrate reductase 1, subunit alpha YP_003036606.1 TIGRFAM: nitrite transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sbc:SbBS512_E1391 nitrite extrusion protein 1 YP_003036607.1 KEGG: ssn:SSON_1954 hypothetical protein YP_003036608.1 KEGG: sfv:SFV_1238 nitrate/nitrite sensor protein NarX; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein YP_003036609.1 two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase YP_003036610.1 KEGG: elf:LF82_2746 uncharacterized protein YchO YP_003036611.1 PFAM: DsrE family protein; KEGG: sdy:SDY_1271 hypothetical protein YP_003036612.1 PFAM: cation transport protein ChaC; KEGG: sbc:SbBS512_E1385 ChaC protein YP_003036613.1 in Escherichia coli this protein ly regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions YP_003036614.1 TIGRFAM: calcium/proton exchanger; PFAM: sodium/calcium exchanger membrane region; KEGG: ssn:SSON_1961 calcium/sodium:proton antiporter YP_003036615.1 KEGG: ssn:SSON_1962 hypothetical protein YP_003036616.1 KEGG: sbo:SBO_1851 hypothetical protein YP_003036617.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_003036618.1 KEGG: sbc:SbBS512_E1378 sirB1 protein YP_003036619.1 PFAM: invasion gene expression up-regulator SirB; KEGG: ssn:SSON_1965 transcriptional regulator YP_003036620.1 HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB YP_003036621.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_003036622.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_003036623.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein YP_003036624.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_003036625.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_003036626.1 role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport YP_003036627.1 YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function YP_003036628.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_003036629.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_003036630.1 KEGG: sbc:SbBS512_E1366 hypothetical protein YP_003036631.1 TIGRFAM: outer membrane autotransporter barrel domain protein; PFAM: Pertactin; Autotransporter beta- domain protein; KEGG: sfx:S1289 adhesion and penetration protein YP_003036632.1 Positively regulates the dhaKLM operon from a sigma-70 promoter YP_003036633.1 with DhaL and DhaM forms dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone; DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase YP_003036634.1 with DhaK and DhaM catalyzes the phosphorylation of dihydroxyacetone YP_003036635.1 phosphotransferaese subunit; phosphorylates dihydroxyacetone along with DhaK/DhaL YP_003036636.1 periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell YP_003036637.1 KEGG: sbc:SbBS512_E1354 hypothetical protein YP_003036638.1 PFAM: transglycosylase; KEGG: sdy:SDY_1234 hypothetical protein YP_003036639.1 PFAM: YcgR family protein; type IV pilus assembly PilZ; KEGG: ssn:SSON_1186 hypothetical protein YP_003036640.1 PFAM: lytic transglycosylase catalytic; KEGG: ssn:SSON_1184 murein transglycosylase E YP_003036641.1 catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine YP_003036642.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli YP_003036643.1 catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA YP_003036644.1 catalyzes the oxidative deamination of D-amino acids YP_003036645.1 PFAM: SpoVR family protein YP_003036646.1 Multifunctional regulator of fatty acid metabolism YP_003036647.1 involved in regulation of intracellular pH under alkaline conditions YP_003036648.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein YP_003036649.1 binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization YP_003036650.1 binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization YP_003036651.1 PFAM: protein of unknown function UPF0153; KEGG: sfv:SFV_1188 hypothetical protein YP_003036652.1 PFAM: fumarylacetoacetate hydrolase; KEGG: sbc:SbBS512_E1335 fumarylacetoacetate hydrolase family protein YP_003036653.1 PFAM: protein of unknown function DUF709; KEGG: ssn:SSON_1168 hypothetical protein YP_003036654.1 PFAM: peptidase domain protein; KEGG: elf:LF82_2732 uncharacterized protein YcgK YP_003036655.1 PFAM: Fels-1 Propage domain protein YP_003036656.1 blocks the formation of polar Z-ring septums YP_003036657.1 ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums YP_003036658.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_003036659.1 KEGG: sfl:SF1159 hypothetical protein YP_003036660.1 KEGG: ssn:SSON_1161 hypothetical protein YP_003036661.1 KEGG: elf:LF82_3545 uncharacterized protein YmgF YP_003036662.1 PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: sfx:S1241 hypothetical protein YP_003036663.1 KEGG: elf:LF82_3542 uncharacterized protein YmgC YP_003036665.1 KEGG: elf:LF82_3540 hypothetical protein YP_003036667.1 PFAM: EAL domain protein; BLUF domain protein; SMART: EAL domain protein YP_003036668.1 PFAM: regulatory protein MerR; SMART: regulatory protein MerR; KEGG: sbc:SbBS512_E1317 transcriptional regulator MlrA YP_003036669.1 PFAM: protein of unknown function DUF1398 YP_003036670.1 KEGG: sdy:SDY_2015 hypothetical protein YP_003036671.1 Converts isocitrate to alpha ketoglutarate YP_003036672.1 catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA YP_003036673.1 PFAM: NUDIX hydrolase; KEGG: sfv:SFV_1169 phosphohydrolase YP_003036674.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_003036675.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis YP_003036676.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_003036677.1 response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress YP_003036678.1 PFAM: PhoQ Sensor domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; KEGG: sdy:SDY_2023 sensor protein PhoQ YP_003036679.1 PFAM: cupin; SMART: transcription factor jumonji jmjC domain protein; KEGG: sbc:SbBS512_E1306 cupin family protein YP_003036680.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_003036681.1 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase YP_003036682.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component YP_003036683.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component YP_003036684.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate YP_003036685.1 KEGG: efe:EFER_1286 conserved hypothetical protein; inner membrane protein YP_003036686.1 KEGG: elf:LF82_2726 inner membrane protein YcfZ YP_003036687.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_003036688.1 PFAM: IS1 transposase; KEGG: hdu:HD1970 insertion element IS1 1/5/6 protein InsB YP_003036689.1 PFAM: Insertion element protein; KEGG: hdu:HD1971 insertion element IS1 1/2/3/5/6 protein InsA YP_003036690.1 part of the ATP-dependent transporter LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_003036691.1 outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone YP_003036692.1 part of the ATP-dependent transporter LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_003036693.1 PFAM: acyltransferase 3; KEGG: ssn:SSON_1135 hypothetical protein YP_003036694.1 KEGG: sfv:SFV_1134 transcription-repair coupling factor; TIGRFAM: transcription-repair coupling factor; PFAM: TRCF domain protein; transcription factor CarD; helicase; DEAD/DEAH box helicase; type III restriction protein res subunit; SMART: DEAD-like helicase ; helicase YP_003036695.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; peptidoglycan-binding LysM; SMART: peptidoglycan-binding LysM; KEGG: sdy:SDY_2037 hypothetical protein YP_003036696.1 PFAM: protein of unknown function DUF1471; KEGG: elf:LF82_0232 UPF0379 protein YcfR YP_003036697.1 PFAM: regulatory protein TetR; KEGG: ssn:SSON_1131 hypothetical protein YP_003036698.1 PFAM: 17 kDa surface antigen; KEGG: ssn:SSON_1130 hypothetical protein YP_003036699.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; KEGG: sfx:S1193 respiratory NADH dehydrogenase YP_003036700.1 PFAM: protein of unknown function UPF0227; KEGG: sfx:S1192 hypothetical protein YP_003036701.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides YP_003036702.1 catalyzes the phosphorylation of thiamine to thiamine phosphate YP_003036703.1 TIGRFAM: membrane lipoprotein lipid attachment site; KEGG: sdy:SDY_2045 hypothetical protein YP_003036704.1 PFAM: protein of unknown function DUF1425; KEGG: ssn:SSON_1124 hypothetical protein YP_003036705.1 PFAM: histidine triad (HIT) protein; KEGG: ssn:SSON_1123 purine nucleoside phosphoramidase YP_003036706.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: sdy:SDY_2048 ferric-rhodotorulic acid outer membrane transporter YP_003036707.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_003036708.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: sdy:SDY_2050 predicted metallodependent hydrolase YP_003036709.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the subunit beta on the DNA YP_003036710.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_003036711.1 PFAM: aminodeoxychorismate lyase; KEGG: sbc:SbBS512_E2227 hypothetical protein YP_003036712.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate YP_003036713.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_003036714.1 carries the fatty acid chain in fatty acid biosynthesis YP_003036715.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_003036716.1 TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase; KEGG: sbc:SbBS512_E2232 malonyl CoA-acyl carrier protein transacylase YP_003036717.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_003036718.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_003036719.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_003036720.1 PFAM: protein of unknown function DUF177; KEGG: sdy:SDY_2062 hypothetical protein YP_003036721.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_003036722.1 catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA YP_003036723.1 bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase YP_003036724.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes YP_003036725.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook YP_003036726.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space YP_003036727.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_003036728.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod YP_003036729.1 makes up the distal portion of the flagellar basal body rod YP_003036730.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod YP_003036731.1 the hook connects flagellar basal body to the flagellar filament YP_003036732.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production YP_003036733.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_003036734.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella YP_003036735.1 required for the assembly of the flagellar basal body P-ring YP_003036736.1 regulates the flagellar specific sigma28 transcription factor YP_003036737.1 KEGG: ssn:SSON_1090 protein of flagellar biosynthesis YP_003036738.1 TIGRFAM: integral membrane protein MviN; KEGG: sbc:SbBS512_E2257 integral membrane protein MviN YP_003036739.1 KEGG: elf:LF82_2713 virulence factor MviM homolog YP_003036740.1 KEGG: ssn:SSON_1087 hypothetical protein YP_003036741.1 KEGG: ssn:SSON_1086 ribosomal-protein-S5-alanine N-acetyltransferase YP_003036742.1 Confers resistance to norfloxacin and enoxacin YP_003036743.1 cofactor involved in the reduction of disulfides YP_003036744.1 KEGG: sfv:SFV_1085 hypothetical protein YP_003036745.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_003036746.1 PFAM: DinI family protein; KEGG: ssn:SSON_1081 DNA damage-inducible protein I YP_003036747.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing YP_003036748.1 catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids YP_003036749.1 KEGG: sfv:SFV_1081 hypothetical protein YP_003036750.1 PFAM: cytochrome B561; KEGG: sbc:SbBS512_E2271 nickel-dependent hydrogenase b-type cytochrome subunit YP_003036751.1 PFAM: YceI family protein; KEGG: ssn:SSON_1076 hypothetical protein YP_003036752.1 PFAM: rhodanese; SMART: Rhodanese domain protein; KEGG: sfv:SFV_1078 hypothetical protein YP_003036753.1 acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA YP_003036754.1 Confers resistance to fosfomycin and deoxycholate YP_003036755.1 KEGG: sdy:SDY_2299 hypothetical protein YP_003036756.1 PFAM: protein of unknown function DUF1375; KEGG: sdy:SDY_2300 predicted lipoprotein YP_003036757.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space YP_003036758.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan YP_003036759.1 required for the transfer of succinyl residues to the glucan backbone YP_003036760.1 PFAM: phospholipase D/transphosphatidylase; SMART: phospholipase D/transphosphatidylase; KEGG: sfx:S1116 synthase YP_003036761.1 PFAM: Appr-1-p processing domain protein; SMART: Appr-1-p processing domain protein; KEGG: ssn:SSON_1058 hypothetical protein YP_003036762.1 KEGG: ssn:SSON_1057 hypothetical protein YP_003036763.1 involved in autoagglutination of curliated cells; not involved in production of curli fibers YP_003036764.1 PFAM: Curlin associated repeat protein; KEGG: sbo:SBO_2026 cryptic curlin major subunit YP_003036765.1 CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface YP_003036766.1 activates the csgBA and csgDEFG operons involved in biofilm formation YP_003036767.1 chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex YP_003036768.1 nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex YP_003036769.1 PFAM: Curli production assembly/transport component CsgG YP_003036770.1 PFAM: protein of unknown function DUF1097; KEGG: sbo:SBO_2032 hypothetical protein YP_003036771.1 PFAM: cytoplasmic chaperone TorD family protein; KEGG: sbc:SbBS512_E2294 chaperone, TorD family YP_003036772.1 PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: sbc:SbBS512_E2295 PHP domain protein YP_003036773.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: ssn:SSON_1042 dehydrogenase YP_003036774.1 PFAM: transposase IS3/IS911 family protein YP_003036775.1 PFAM: Integrase catalytic region; KEGG: seh:SeHA_C4704 ISEc16, orfB YP_003036776.1 TIGRFAM: diguanylate cyclase; SMART: GGDEF domain containing protein; KEGG: elf:LF82_2700 inner membrane protein YcdT YP_003036777.1 outer membrane protein essential for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PGA); adhesin required for biofilm formation; PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface; member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia YP_003036778.1 in Yersinia this protein is involved in biofilm formation and hemin adsorption; related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1,6-N-acetyl-D-glucosamine (PGA) export YP_003036779.1 predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein YP_003036780.1 in Yersinia this gene is involved in biofilm formation and hemin adsorption; in Escherichia coli it is involved in PGA biosynthesis and export YP_003036781.1 KEGG: sbc:SbBS512_E2301 protein PhoH YP_003036782.1 TIGRFAM: Dyp-type peroxidase family; KEGG: sbo:SBO_2039 hypothetical protein YP_003036783.1 KEGG: ssn:SSON_1037 hypothetical protein YP_003036784.1 TIGRFAM: FTR1 family protein; KEGG: ssn:SSON_1036 high-affinity iron permease YP_003036785.1 TIGRFAM: sodium/proline symporter; SSS sodium solute transporter superfamily; KEGG: sbo:SBO_2042 major sodium/proline symporter YP_003036786.1 KEGG: sbc:SbBS512_E2303 hypothetical protein YP_003036787.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein YP_003036788.1 PFAM: Tetracycline transcriptional regulator YcdC domain protein; regulatory protein TetR; KEGG: sbc:SbBS512_E2305 transcriptional regulator RutR YP_003036789.1 PFAM: Luciferase-like monooxygenase YP_003036790.1 PFAM: isochorismatase hydrolase; KEGG: ssn:SSON_1030 synthetase YP_003036791.1 PFAM: endoribonuclease L-PSP; KEGG: sdy:SDY_0985 hypothetical protein YP_003036792.1 PFAM: alpha/beta hydrolase fold; KEGG: ssn:SSON_1027 acetyltransferase YP_003036793.1 PFAM: nitroreductase; KEGG: elf:LF82_2053 NadH dehydrogenase/NAD(P)H nitroreductase RutE YP_003036794.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: elf:LF82_2054 flavin reductase RutF YP_003036795.1 TIGRFAM: uracil-xanthine permease; PFAM: xanthine/uracil/vitamin C permease; KEGG: ssn:SSON_1024 transport protein YP_003036796.1 KEGG: elf:LF82_3538 uncharacterized protein YmdF YP_003036797.1 stationary phase protein that binds TrpR repressor YP_003036798.1 KEGG: sfv:SFV_1015 hypothetical protein YP_003036799.1 PFAM: histidine acid phosphatase; KEGG: ssn:SSON_1012 glucose-1-phosphatase/inositol phosphatase YP_003036800.1 KEGG: sfx:S1074 hypothetical protein YP_003036801.1 functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock YP_003036802.1 with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA YP_003036803.1 TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor YP_003036804.1 KEGG: sfv:SFV_1007 trimethylamine N-oxide reductase subunit; TIGRFAM: molybdopterin guanine dinucleotide-containing S/N-oxide reductase; trimethylamine-N-oxide reductase TorA; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region YP_003036805.1 TIGRFAM: trimethylamine-N-oxide reductase c-type cytochrome TorC; PFAM: NapC/NirT cytochrome C domain protein; KEGG: efe:EFER_1191 trimethylamine N-oxide (TMAO) reductase I, cytochrome C subunit YP_003036806.1 response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes YP_003036807.1 periplasmic sensory protein associated with the TorRS two-component regulatory system YP_003036808.1 Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide YP_003036809.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sbc:SbBS512_E2322 4Fe-4S binding domain protein YP_003036810.1 PFAM: GnsAGnsB family protein; KEGG: ssn:SSON_0999 GnsA YP_003036811.1 KEGG: ssn:SSON_0998 cold shock gene YP_003036812.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: ssn:SSON_0997 DNA-binding transcriptional regulator YP_003036813.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: sdy:SDY_0964 cold shock-like protein YP_003036814.1 KEGG: sbc:SbBS512_E2328 inner membrane protein YP_003036815.1 KEGG: ssn:SSON_0993 regulator YP_003036816.1 PFAM: protein of unknown function DUF1017; KEGG: ssn:SSON_0992 hypothetical protein YP_003036817.1 PFAM: protein of unknown function DUF940 membrane lipoprotein KEGG: sbo:SBO_2246 hypothetical protein YP_003036818.1 PFAM: polysaccharide export protein; KEGG: sfv:SFV_0992 function in exopolysaccharide production YP_003036819.1 Etk and Etp are a tyrosine kinase-tyrosine phosphatase pair, etp dephosphorylates etk YP_003036820.1 KEGG: sbo:SBO_2249 cryptic autophosphorylating protein tyrosine kinase Etk; TIGRFAM: capsular exopolysaccharide family; PFAM: lipopolysaccharide biosynthesis protein YP_003036821.1 PFAM: histidine acid phosphatase; KEGG: ssn:SSON_0987 phosphoanhydride phosphorylase YP_003036822.1 expressed during stationary phase YP_003036823.1 TIGRFAM: cytochrome d ubiquinol oxidase subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II; KEGG: ssn:SSON_0985 probable third cytochrome oxidase subunit II YP_003036824.1 PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: sfv:SFV_0987 third cytochrome oxidase subunit I YP_003036825.1 PFAM: HupH hydrogenase expression protein; KEGG: sbc:SbBS512_E2338 hydrogenase-1 operon protein HyaF YP_003036826.1 involved in processing hydrogenase proteins HyaA and HyaB YP_003036827.1 HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1) YP_003036828.1 TIGRFAM: Ni/Fe-hydrogenase, b-type cytochrome subunit; PFAM: cytochrome B561; KEGG: sdy:SDY_0949 hydrogenase 1 b-type cytochrome subunit YP_003036829.1 involved in hydrogen cycling during fermentative growth YP_003036830.1 KEGG: sdy:SDY_0947 hydrogenase-1 small subunit; TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit YP_003036831.1 PFAM: protein of unknown function UPF0005; KEGG: sdy:SDY_0945 hypothetical protein YP_003036832.1 transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs YP_003036833.1 catalyzes the hydrolysis of acylphosphate YP_003036834.1 PFAM: protein of unknown function methylase SMART: PUA domain containing protein; KEGG: elf:LF82_2696 UPF0064 protein YccW YP_003036835.1 TIGRFAM: hemimethylated DNA binding protein; PFAM: Hemimethylated DNA-binding region; KEGG: ssn:SSON_0971 hypothetical protein YP_003036836.1 PFAM: CoA-binding protein; KEGG: sbc:SbBS512_E2350 CoA-binding protein YP_003036837.1 KEGG: ssn:SSON_0968 hypothetical protein YP_003036838.1 catalyzes the formation of methylglyoxal from glycerone phosphate YP_003036839.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand YP_003036840.1 PFAM: protein of unknown function DUF307; KEGG: sbc:SbBS512_E2354 hypothetical protein YP_003036841.1 TIGRFAM: hypothetical protein; integral membrane protein, YccS/YhfK family; PFAM: protein of unknown function DUF893 YccS/YhfK; KEGG: ssn:SSON_0964 hypothetical protein YP_003036842.1 PFAM: TfoX domain protein; KEGG: ssn:SSON_0963 hypothetical protein YP_003036843.1 TIGRFAM: cell division inhibitor SulA; PFAM: cell division inhibitor SulA; KEGG: ssn:SSON_0962 SOS cell division inhibitor YP_003036845.1 OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d YP_003036846.1 PFAM: protein of unknown function DUF1047; KEGG: sdy:SDY_0929 hypothetical protein YP_003036847.1 KEGG: ssn:SSON_0959 ATP-dependent protease YP_003036848.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_003036849.1 PFAM: ribosome modulation factor; KEGG: sdy:SDY_0926 ribosome modulation factor YP_003036850.1 PFAM: protein of unknown function DUF330; KEGG: sfv:SFV_0961 hypothetical protein YP_003036851.1 PFAM: hypothetical protein; KEGG: sdy:SDY_0924 paraquat-inducible protein B YP_003036852.1 TIGRFAM: integral membrane protein, PqiA family; PFAM: paraquat-inducible protein A; KEGG: sfv:SFV_0959 paraquat-inducible protein A YP_003036853.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth YP_003036854.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA YP_003036855.1 PFAM: MOSC domain containing protein; MOSC domain protein beta barrel domain protein; ferredoxin; KEGG: sbc:SbBS512_E2371 MOSC domain protein YP_003036856.1 PFAM: protein of unknown function DUF1379; KEGG: sbc:SbBS512_E2370 hypothetical protein YP_003036857.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_003036858.1 PFAM: Pili assembly chaperone, N-terminal; Pili assembly chaperone, C-terminal; KEGG: ssn:SSON_0948 hypothetical protein YP_003036859.1 PFAM: fimbrial protein; KEGG: ssn:SSON_0947 fimbrial-like protein YP_003036860.1 PFAM: fimbrial protein; KEGG: sbc:SbBS512_E2375 fimbrial protein YP_003036861.1 PFAM: fimbrial protein; KEGG: sbc:SbBS512_E2376 fimbrial protein YP_003036862.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: sfv:SFV_0949 outer membrane protein YP_003036863.1 PFAM: Pili assembly chaperone, N-terminal; Pili assembly chaperone, C-terminal; KEGG: ssn:SSON_0943 chaperone YP_003036864.1 PFAM: fimbrial protein; KEGG: sbc:SbBS512_E2380 fimbrial protein YP_003036865.1 PFAM: NADPH-dependent FMN reductase; NAD(P)H dehydrogenase (quinone); KEGG: sbc:SbBS512_E2381 NADPH-dependent FMN reductase YP_003036866.1 part of the ABC type transporter SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease YP_003036867.1 catalyzes the release of sulfite from alkanesulfonates YP_003036868.1 part of the ABC type transporter for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease YP_003036869.1 part of the ABC type transporter SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease YP_003036870.1 TIGRFAM: aminopeptidase N; PFAM: peptidase M1 membrane alanine aminopeptidase YP_003036871.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate YP_003036872.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_003036873.1 outer membrane porin F; 1a; Ia; b YP_003036874.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_003036875.1 PFAM: beta-lactamase; KEGG: sbo:SBO_2218 hypothetical protein YP_003036876.1 PFAM: protein of unknown function DUF882; peptidase M15A; KEGG: sdy:SDY_2331 hypothetical protein YP_003036877.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; peptidoglycan-binding protein; KEGG: sbo:SBO_2216 hypothetical protein YP_003036878.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects YP_003036879.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division YP_003036880.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division YP_003036881.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA YP_003036882.1 PFAM: protein of unknown function DUF218; KEGG: elf:LF82_2680 uncharacterized protein YcbC YP_003036883.1 KEGG: sbc:SbBS512_E2404 hypothetical protein YP_003036884.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_003036885.1 PFAM: protein of unknown function DUF343; KEGG: ssn:SSON_0919 hypothetical protein YP_003036886.1 PFAM: protein of unknown function DUF1006; KEGG: sdy:SDY_2342 hypothetical protein YP_003036887.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_003036888.1 involved in the transport of lipid A across the inner membrane YP_003036889.1 TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein; beta-lactamase; KEGG: sdy:SDY_2345 hypothetical protein YP_003036890.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_003036891.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_003036892.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_003036893.1 PFAM: peptidase M48 Ste24p; KEGG: ssn:SSON_0911 heat shock protein YP_003036894.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_003036895.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_003036896.1 PFAM: protein of unknown function DUF421; KEGG: ssn:SSON_0907 hypothetical protein YP_003036897.1 PFAM: protein of unknown function DUF181; KEGG: ssn:SSON_0906 hypothetical protein YP_003036898.1 TIGRFAM: formate/nitrite transporter; PFAM: formate/nitrite transporter; KEGG: ssn:SSON_0905 formate transporter YP_003036899.1 KEGG: ssn:SSON_0904 formate acetyltransferase 1; TIGRFAM: formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical YP_003036900.1 activates pyruvate formate-lyase 1 under anaerobic conditions YP_003036901.1 PFAM: NAD(P)H dehydrogenase (quinone); NADPH-dependent FMN reductase; KEGG: sbo:SBO_2185 hypothetical protein YP_003036902.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: sbo:SBO_2184 transcriptional regulator LysR-type YP_003036903.1 PFAM: amino acid permease-associated region YP_003036904.1 PFAM: major facilitator superfamily MFS_1; KEGG: sdy:SDY_2363 MFS family transporter protein YP_003036905.1 PFAM: isochorismatase hydrolase; KEGG: ssn:SSON_0898 hypothetical protein YP_003036906.1 PFAM: DMSO reductase anchor subunit (DmsC); KEGG: sbc:SbBS512_E2432 anaerobic dimethyl sulfoxide reductase, C subunit YP_003036907.1 TIGRFAM: dimethylsulfoxide reductase, chain B; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: ssn:SSON_0896 anaerobic dimethyl sulfoxide reductase subunit B YP_003036908.1 TIGRFAM: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region YP_003036909.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_003036910.1 PFAM: ATPase AAA; ATPase associated with various cellular activities AAA_5; SMART: ATPase AAA; KEGG: sdy:SDY_2369 recombination factor protein RarA YP_003036911.1 participates with LolB in the incorporation of lipoprotein into the outer membrane YP_003036912.1 DNA-binding membrane protein required for chromosome resolution and partitioning YP_003036913.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transporter YP_003036914.1 catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding YP_003036915.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_003036916.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_003036917.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_003036918.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_003036919.1 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates YP_003036920.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_003036921.1 inhibits DNA replication at both initiation and elongation steps; stationary phase and starvation inducible YP_003036922.1 with MacA is involved in the export of macrolide YP_003036923.1 confers macrolide resistance via active drug efflux YP_003036924.1 PFAM: protein of unknown function DUF535; KEGG: ssn:SSON_0864 enzyme YP_003036925.1 KEGG: sfx:S0876 hypothetical protein YP_003036926.1 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure YP_003036927.1 PFAM: protein of unknown function DUF340 membrane; KEGG: sbo:SBO_0807 surface protein YP_003036928.1 catalyzes the reduction of hydroxylamine to ammonia and water YP_003036929.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; oxidoreductase FAD-binding domain protein; KEGG: sbc:SbBS512_E2459 NADH oxidoreductase hcr YP_003036930.1 catalyzes the formation of acetate from pyruvate YP_003036931.1 low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine YP_003036932.1 PFAM: NAD-dependent epimerase/dehydratase; NmrA family protein; 3-beta hydroxysteroid dehydrogenase/isomerase; KEGG: sbc:SbBS512_E2462 NAD dependent epimerase/dehydratase family protein YP_003036933.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; KEGG: ssn:SSON_0854 nucleotide di-P-sugar epimerase or dehydratase YP_003036934.1 KEGG: sdy:SDY_2396 regulator; PFAM: N-acetylmuramoyl-L-alanine amidase family 2; SMART: N-acetylmuramoyl-L-alanine amidase family 2 YP_003036935.1 PFAM: protein of unknown function DUF74; KEGG: sdy:SDY_2397 hypothetical protein YP_003036936.1 induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS YP_003036937.1 With ArtMQJI transports arginine across the inner membrane YP_003036938.1 TIGRFAM: cationic amino acid ABC transporter periplasmic binding protein; KEGG: ssn:SSON_0848 arginine 3rd transporter periplasmic binding protein YP_003036939.1 with ArtPMJI transports arginine across the inner membrane YP_003036940.1 with ArtPQJI acts to transport arginine across the inner membrane YP_003036941.1 TIGRFAM: cationic amino acid ABC transporter periplasmic binding protein; KEGG: sbo:SBO_0794 arginine 3rd transporter periplasmic binding protein YP_003036942.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA YP_003036943.1 KEGG: sdy:SDY_0737 hypothetical protein YP_003036944.1 KEGG: sdy:SDY_0738 putrescine transporter subunit: membrane component of ABC superfamily YP_003036945.1 KEGG: efe:EFER_0999 putrescine transporter subunit: membrane component of ABC superfamily YP_003036946.1 part of the PotFGHI ATP-dependent putrescine transporter YP_003036947.1 PFAM: extracellular solute-binding protein family 1; KEGG: sbc:SbBS512_E2477 putrescine ABC transporter periplasmic putrescine-binding protein YP_003036948.1 KEGG: ssn:SSON_0838 sensory transduction regulator YP_003036949.1 responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 YP_003036950.1 NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds YP_003036951.1 YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function YP_003036952.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase YP_003036953.1 KEGG: ssn:SSON_0833 hypothetical protein YP_003036954.1 TIGRFAM: YidE/YbjL duplication; PFAM: YidE/YbjL duplication domain protein; TrkA-C domain protein; KEGG: sbc:SbBS512_E2485 transporter YP_003036955.1 PFAM: transcriptional activator Ogr/delta; KEGG: sbc:SbBS512_E2486 phage transcriptional activator, Ogr/delta YP_003036956.1 PFAM: Resolvase domain; KEGG: stt:t2667 DNA-invertase YP_003036957.1 PFAM: Tail Collar domain protein; KEGG: stt:t1351 bacteriophage tail fiber protein YP_003036958.1 PFAM: tail assembly chaperone gp38; KEGG: stt:t1349 bacteriophage tail fiber assembly protein YP_003036959.1 PFAM: tail assembly chaperone gp38; KEGG: stt:t3435 hypothetical protein YP_003036960.1 KEGG: elf:LF82_p389 variable tail fibre protein YP_003036961.1 TIGRFAM: phage tail protein I; KEGG: elf:LF82_p390 phage tail protein YP_003036962.1 PFAM: Baseplate J family protein; KEGG: elf:LF82_p391 phage baseplate assembly protein YP_003036963.1 PFAM: GPW/gp25 family protein; KEGG: elf:LF82_p392 phage baseplate assembly protein YP_003036964.1 TIGRFAM: phage baseplate assembly protein V; PFAM: baseplate assembly protein V; KEGG: stt:t3429 phage baseplate assembly protein YP_003036965.1 KEGG: esa:ESA_02491 hypothetical protein YP_003036966.1 TIGRFAM: phage virion morphogenesis protein; PFAM: virion morphogenesis ( tail completion) protein; KEGG: stt:t3428 phage tail protein YP_003036967.1 PFAM: P2 phage tail completion R family protein; KEGG: sed:SeD_A3040 phage tail completion protein R YP_003036968.1 KEGG: elf:LF82_p396 regulatory protein YP_003036969.1 PFAM: capsid scaffolding; KEGG: sbo:SBO_0759 capsid scaffolding protein YP_003036970.1 PFAM: protein of unknown function DUF264; terminase ATPase; KEGG: stt:t3417 terminase, ATPase YP_003036971.1 TIGRFAM: phage portal protein, PBSX family; PFAM: portal protein; KEGG: stt:t3416 capsid portal protein YP_003036972.1 PFAM: RNA-directed DNA polymerase (Reverse transcriptase); KEGG: har:HEAR0006 hypothetical protein YP_003036973.1 KEGG: har:HEAR0007 hypothetical protein YP_003036975.1 PFAM: DinI family protein; KEGG: stm:STM2727 hypothetical protein YP_003036976.1 KEGG: stt:t3411 hypothetical protein YP_003036977.1 PFAM: regulatory CII family protein; replication gene A; KEGG: elf:LF82_p407 replication protein for prophage YP_003036978.1 KEGG: sbo:SBO_0749 hypothetical protein YP_003036979.1 PFAM: CI repressor; KEGG: sbo:SBO_0748 repressor protein YP_003036980.1 KEGG: sdy:SDY_1763 hypothetical protein YP_003036981.1 PFAM: integrase; KEGG: stt:t3400 bacteriophage integrase YP_003036982.1 KEGG: stt:t3767 hypothetical protein YP_003036983.1 PFAM: regulatory protein TetR; KEGG: sbc:SbBS512_E2499 TetR family transcriptional regulator YP_003036984.1 PFAM: major facilitator superfamily MFS_1; KEGG: elf:LF82_2659 inner membrane protein YbjJ YP_003036985.1 TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase type 3; haloacid dehalogenase; sucrose-6F-phosphate phosphohydrolase; KEGG: sfv:SFV_0829 hypothetical protein YP_003036986.1 KEGG: sfv:SFV_0828 hypothetical protein YP_003036987.1 PFAM: major facilitator superfamily MFS_1 YP_003036988.1 KEGG: ssn:SSON_0826 undecaprenyl pyrophosphate phosphatase; PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related YP_003036989.1 PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR YP_003036990.1 penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains YP_003036991.1 PFAM: glutathione S-transferase domain; KEGG: sfx:S0831 transferase YP_003036992.1 PFAM: glucose sorbosone dehydrogenase; KEGG: sbo:SBO_0733 dehydrogenase YP_003036993.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing YP_003036994.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit YP_003036995.1 KEGG: sbo:SBO_0726 hypothetical protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein YP_003036996.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: sbc:SbBS512_E2516 glutathione ABC transporter permease GsiD YP_003036997.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: sdy:SDY_0756 transporter permease protein YP_003036998.1 PFAM: extracellular solute-binding protein family 5; KEGG: ssn:SSON_0812 transporter YP_003036999.1 with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains YP_003037000.1 PFAM: peptidase T2 asparaginase 2; KEGG: ssn:SSON_0810 L-asparaginase YP_003037001.1 is involved in the formation of active molybdenum cofactor and the chelation of molybdenum YP_003037002.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase YP_003037003.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies YP_003037004.1 KEGG: sfv:SFV_0807 pyruvate formate-lyase 2 activating enzyme; TIGRFAM: glycyl-radical enzyme activating protein family; PFAM: radical SAM protein YP_003037005.1 KEGG: elf:LF82_2650 formate acetyltransferase 3; TIGRFAM: pyruvate formate-lyase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical YP_003037006.1 TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase type 3; sucrose-6F-phosphate phosphohydrolase; Haloacid dehalogenase domain protein hydrolase; KEGG: sfv:SFV_0805 hypothetical protein YP_003037007.1 PFAM: protein of unknown function DUF1479; KEGG: sbo:SBO_0711 hypothetical protein YP_003037008.1 PFAM: ABC transporter; SMART: ATPase AAA YP_003037009.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: sdy:SDY_0777 hypothetical protein YP_003037010.1 PFAM: citrate transporter; KEGG: ssn:SSON_0797 hypothetical protein YP_003037011.1 transcriptional regulator that represses the manganese transporter MntH when manganese is present YP_003037012.1 KEGG: sbc:SbBS512_E2532 hypothetical protein YP_003037013.1 PFAM: sulfatase; KEGG: sbc:SbBS512_E2533 sulfatase family protein YP_003037014.1 OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains YP_003037015.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: sbc:SbBS512_E2535 threonine/homoserine efflux transporter RhtA YP_003037016.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage YP_003037017.1 similar to periplasmic-binding component of ABC transporters YP_003037018.1 similar to permease of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine YP_003037019.1 similar to ATP-binding component of ABC transporters YP_003037020.1 PFAM: MscS Mechanosensitive ion channel; KEGG: efe:EFER_2300 hypothetical protein YP_003037021.1 PFAM: protein of unknown function DUF890; KEGG: sbc:SbBS512_E2543 hypothetical protein YP_003037022.1 PFAM: protein of unknown function DUF1471; KEGG: sbc:SbBS512_E2544 hypothetical protein YP_003037023.1 Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein YP_003037024.1 PFAM: 2OG-Fe(II) oxygenase; SMART: prolyl 4-hydroxylase subunit alpha YP_003037025.1 PFAM: zinc finger DksA/TraR C4-type; KEGG: ssn:SSON_0782 hypothetical protein YP_003037026.1 PFAM: protein of unknown function DUF1471; KEGG: sfv:SFV_0785 hypothetical protein YP_003037027.1 PFAM: malate/L-lactate dehydrogenase; KEGG: ssn:SSON_0780 dehydrogenase YP_003037028.1 PFAM: glycosyl transferase, family 3-like; KEGG: sbo:SBO_0688 hypothetical protein YP_003037029.1 helicase involved in DNA repair and perhaps also replication YP_003037030.1 PFAM: conserved hypothetical protein; KEGG: efe:EFER_2310 hypothetical protein YP_003037031.1 this helicase is not essential cell growth YP_003037032.1 PFAM: TetR family transcriptional regulator ; regulatory protein TetR; KEGG: sfv:SFV_0779 DNA-binding transcriptional regulator YP_003037033.1 PFAM: secretion protein HlyD; KEGG: sfv:SFV_0778 hypothetical protein YP_003037034.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: hypothetical protein YP_003037035.1 PFAM: ABC transporter; KEGG: ssn:SSON_0772 hypothetical protein YP_003037036.1 PFAM: ABC transporter; KEGG: ssn:SSON_0771 hypothetical protein YP_003037037.1 KEGG: sbc:SbBS512_E2560 hypothetical protein YP_003037038.1 PFAM: endonuclease/exonuclease/phosphatase; KEGG: ssn:SSON_0769 hypothetical protein YP_003037039.1 PFAM: phospholipase D/transphosphatidylase; SMART: phospholipase D/transphosphatidylase; KEGG: elf:LF82_2631 cardiolipin synthetase YbhO YP_003037041.1 PFAM: protein of unknown function UPF0005; KEGG: sfv:SFV_0770 hypothetical protein YP_003037042.1 PFAM: protein of unknown function UPF0005; KEGG: ssn:SSON_0765 hypothetical protein YP_003037043.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin YP_003037044.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin YP_003037045.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_003037046.1 TIGRFAM: molybdenum cofactor biosynthesis protein B; molybdenum cofactor synthesis protein; PFAM: molybdopterin binding domain; KEGG: ssn:SSON_0761 molybdopterin biosynthesis, protein B YP_003037047.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_003037048.1 PFAM: protein of unknown function UPF0052 and CofD; KEGG: ssn:SSON_0759 structural protein YP_003037049.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_003037050.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_003037051.1 methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth YP_003037052.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine YP_003037053.1 KEGG: ssn:SSON_0754 biotin synthesis; TIGRFAM: biotin synthase; PFAM: biotin and thiamin synthesis associated; radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_003037054.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate YP_003037055.1 YbhB; similar to rat and human kinase inhibitory proteins YP_003037057.1 PFAM: virulence-related outer membrane protein; KEGG: sbo:SBO_1623 membrane protein precursor YP_003037058.1 PFAM: protein of unknown function DUF1983; Fibronectin type III domain protein; KEGG: elf:LF82_p179 host specificity protein YP_003037059.1 PFAM: lambda tail assembly I; KEGG: hypothetical protein YP_003037060.1 PFAM: NLP/P60 protein; SMART: Mov34/MPN/PAD-1 family protein YP_003037061.1 TIGRFAM: phage minor tail protein L; PFAM: minor tail protein L; KEGG: elf:LF82_p176 minor tail protein YP_003037062.1 PFAM: minor tail family protein; KEGG: elf:LF82_p175 minor tail protein YP_003037063.1 TIGRFAM: phage tail tape measure protein, lambda family; PFAM: Prophage tail length tape measure; KEGG: elf:LF82_p174 tail component of prophage YP_003037064.1 TIGRFAM: phage tail assembly protein T; PFAM: Minor tail T family protein; KEGG: ssn:SSON_2418 tail component of prophage YP_003037065.1 TIGRFAM: phage minor tail protein G; PFAM: minor tail protein G; KEGG: ssn:SSON_2419 tail component of prophage YP_003037066.1 PFAM: hypothetical protein; SMART: Ig domain protein group 2 domain protein; KEGG: elf:LF82_p171 tail component of prophage YP_003037067.1 PFAM: minor tail U YP_003037068.1 PFAM: Prophage minor tail Z family protein; KEGG: ssn:SSON_2422 tail component of prophage YP_003037069.1 PFAM: head-tail attachment protein; KEGG: ssn:SSON_2423 head-tail joining protein of prophage YP_003037070.1 KEGG: ssn:SSON_2424 DNA-packaging protein YP_003037071.1 PFAM: major capsid protein E; KEGG: ssn:SSON_2425 major capsid protein YP_003037072.1 PFAM: lambda head decoration protein D HDPD; KEGG: ssn:SSON_2426 head decoration protein YP_003037073.1 PFAM: peptidase S49 YP_003037074.1 TIGRFAM: phage portal protein, lambda family; PFAM: portal protein lambda; KEGG: ssn:SSON_2428 capsid structural protein of prophage YP_003037075.1 PFAM: Head-to-tail joining protein W gpW family protein; KEGG: ssn:SSON_2429 head-tail joining protein of prophage YP_003037076.1 PFAM: terminase GpA; KEGG: ssn:SSON_2430 DNA packaging protein of prophage YP_003037077.1 PFAM: DNA packaging Nu1; KEGG: elf:LF82_1506 prophage QSR' DNA packaging protein NU1 homolog YP_003037079.1 KEGG: elf:LF82_2580 uncharacterized protein YbcW YP_003037080.1 PFAM: protein of unknown function DUF1398; KEGG: elf:LF82_2579 uncharacterized protein YbcV YP_003037081.1 PFAM: Bor family protein; KEGG: elf:LF82_0244 lipoprotein bor homolog from lambdoid prophage DLP12 YP_003037082.1 PFAM: lysis protein YP_003037083.1 PFAM: glycoside hydrolase family 24; KEGG: sec:SC0349 lysin YP_003037084.1 TIGRFAM: phage holin, lambda family; PFAM: Holin phage lambda; KEGG: sfv:SFV_0278 cell lysis protein YP_003037086.1 PFAM: antitermination protein; KEGG: sfv:SFV_0277 antitermination protein YP_003037087.1 PFAM: metallophosphoesterase; KEGG: efe:EFER_2055 serine/threonine-protein phosphatase YP_003037088.1 PFAM: replication P family protein; KEGG: elf:LF82_p157 replication protein P of bacteriophage YP_003037089.1 TIGRFAM: phage replication protein O; PFAM: replication protein O domain protein YP_003037090.1 PFAM: CII family protein; KEGG: efe:EFER_2070 regulatory protein CII from phage origin YP_003037091.1 KEGG: elf:LF82_p108 Cro protein YP_003037092.1 PFAM: peptidase S24 and S26 domain protein; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: elf:LF82_p107 repressor protein YP_003037093.1 KEGG: elf:LF82_p106 phage regulatory protein N YP_003037094.1 KEGG: efe:EFER_2077 restriction inhibitor protein ral (antirestriction protein) YP_003037096.1 PFAM: Lambda phage regulatory protein CIII; KEGG: sek:SSPA2258 hypothetical protein YP_003037097.1 PFAM: lambda Kil; KEGG: ses:SARI_02674 hypothetical protein YP_003037098.1 PFAM: Host-nuclease inhibitor Gam; KEGG: efe:EFER_2726 host-nuclease inhibitor protein Gam of bacteriophage YP_003037099.1 TIGRFAM: phage recombination protein Bet; PFAM: RecT protein; KEGG: efe:EFER_2727 recombination protein bet from phage origin YP_003037100.1 KEGG: efe:EFER_2728 exonuclease from phage origin YP_003037101.1 PFAM: protein of unknown function DUF1317; KEGG: elf:LF82_p147 hypothetical protein YP_003037102.1 PFAM: protein of unknown function DUF1382; KEGG: elf:LF82_p146 hypothetical protein YP_003037103.1 PFAM: protein of unknown function DUF550 YP_003037105.1 KEGG: elf:LF82_p097 hypothetical protein YP_003037106.1 PFAM: excisionase; KEGG: elf:LF82_p095 excisionase YP_003037107.1 PFAM: lambda integrase ; integrase domain protein SAM domain protein; integrase; KEGG: sfv:SFV_2686 integrase YP_003037108.1 PFAM: DNA-directed RNA polymerase bacteriophage type; KEGG: ppu:PP_2266 DNA-directed RNA polymerase, bacteriophage and mitochondrial type YP_003037109.1 PFAM: glycoside hydrolase family 2 sugar binding; KEGG: elf:LF82_1168 beta-galactosidase YP_003037110.1 transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer YP_003037111.1 outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase family YP_003037112.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_003037113.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_003037114.1 KEGG: sfl:SF0551 homeobox protein YP_003037115.1 involved in zinc efflux across the cytoplasmic membrane YP_003037116.1 TIGRFAM: nicotinamide mononucleotide transporter PnuC; PFAM: Nicotinamide mononucleotide transporter PnuC; KEGG: ssn:SSON_0703 required for NMN transport YP_003037117.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_003037118.1 periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity YP_003037119.1 TIGRFAM: peptidoglycan-associated lipoprotein; PFAM: OmpA/MotB domain protein; KEGG: sfx:S0569 peptidoglycan-associated outer membrane lipoprotein YP_003037120.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_003037121.1 inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins YP_003037122.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_003037123.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_003037124.1 catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components YP_003037125.1 TIGRFAM: cyd operon protein YbgE; KEGG: sdy:SDY_0683 hypothetical protein YP_003037126.1 TIGRFAM: cyd operon protein YbgT; PFAM: membrane bound YbgT family protein; KEGG: sdy:SDY_0682 outer membrane lipoprotein YP_003037127.1 TIGRFAM: cytochrome d ubiquinol oxidase subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II; KEGG: sbc:SbBS512_E0655 cytochrome d ubiquinol oxidase subunit II YP_003037128.1 PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: ssn:SSON_0685 cytochrome d terminal oxidase polypeptide subunit I YP_003037129.1 PFAM: glycoside hydrolase family 38; glycosyl hydrolase 38 domain protein; KEGG: sfv:SFV_0604 alpha-mannosidase YP_003037130.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_003037131.1 regulates the succiny-lCoA synthetase operon YP_003037132.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_003037133.1 catalyzes the interconversion of succinyl-CoA and succinate YP_003037134.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA YP_003037135.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_003037136.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_003037137.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_003037138.1 TIGRFAM: succinate dehydrogenase, hydrophobic membrane anchor protein; KEGG: ssn:SSON_0673 succinate dehydrogenase cytochrome b556 small membrane subunit YP_003037139.1 TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; KEGG: sbc:SbBS512_E0640 succinate dehydrogenase, cytochrome b556 subunit YP_003037140.1 KEGG: efe:EFER_2393 hypothetical protein YP_003037141.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_003037142.1 PFAM: fimbrial protein; KEGG: ssn:SSON_0670 fimbrial-like protein YP_003037143.1 PFAM: fimbrial biogenesis outer membrane usher protein; KEGG: sfx:S0592 outer membrane protein YP_003037144.1 PFAM: Pili assembly chaperone, N-terminal; Pili assembly chaperone, C-terminal; KEGG: sbc:SbBS512_E0634 periplasmic pilus chaperone family protein YP_003037145.1 KEGG: ssn:SSON_0667 hypothetical protein YP_003037146.1 TIGRFAM: membrane protein AbrB duplication; PFAM: ammonia monooxygenase; KEGG: ssn:SSON_0666 transporter YP_003037147.1 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity YP_003037148.1 PFAM: LamB/YcsF family protein; KEGG: sbo:SBO_0572 hypothetical protein YP_003037149.1 TIGRFAM: urea amidolyase; PFAM: allophanate hydrolase subunit 2; SMART: allophanate hydrolase subunit 2 YP_003037150.1 PFAM: allophanate hydrolase subunit 1; SMART: allophanate hydrolase subunit 1 YP_003037151.1 PFAM: protein of unknown function DUF34; KEGG: sbc:SbBS512_E0627 NIF3 family protein YP_003037152.1 TIGRFAM: amino acid/peptide transporter; PFAM: TGF-beta receptor type I/II extracellular region; major facilitator superfamily MFS_1; KEGG: sfx:S0601 transporter YP_003037153.1 UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent YP_003037154.1 PFAM: protein of unknown function DUF1722; KEGG: sfv:SFV_0628 hypothetical protein YP_003037155.1 PFAM: transposase IS4 family protein; KEGG: ssn:SSON_0260 receptor YP_003037158.1 KEGG: sdy:SDY_0635 hypothetical protein YP_003037159.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_003037160.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_003037161.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex YP_003037162.1 sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein YP_003037163.1 response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport YP_003037164.1 KEGG: sbo:SBO_0555 hypothetical protein YP_003037165.1 PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: sbo:SBO_0554 ornithine decarboxylase isozyme, inducible YP_003037166.1 catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system YP_003037167.1 KEGG: sbo:SBO_0552 hypothetical protein YP_003037168.1 KEGG: sbo:SBO_0551 pectinase YP_003037169.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_003037170.1 negative modulator of the initiation of chromosome replication YP_003037171.1 PFAM: alpha/beta hydrolase fold; PGAP1 family protein; KEGG: sbo:SBO_0548 hypothetical protein YP_003037172.1 PFAM: CopG domain protein DNA-binding domain protein; KEGG: ssn:SSON_0639 LexA regulated protein YP_003037173.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_003037174.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer YP_003037175.1 KEGG: sfl:SF0611 hypothetical protein YP_003037176.1 PFAM: outer membrane porin; KEGG: sbc:SbBS512_E0569 outer membrane porin, OprD family YP_003037177.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_003037179.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_003037180.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate YP_003037181.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate YP_003037182.1 PFAM: ROK family protein; KEGG: ssn:SSON_0630 transcriptional repressor of nag (N-acetylglucosamine) operon YP_003037183.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: haloacid dehalogenase; KEGG: sdy:SDY_0609 UMP phosphatase YP_003037184.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP YP_003037185.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q YP_003037186.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_003037187.1 PFAM: PhoH family protein; KEGG: sdy:SDY_0596 ATP-binding protein in pho regulon YP_003037188.1 PFAM: protein of unknown function UPF0054; KEGG: sbo:SBO_0523 hypothetical protein YP_003037189.1 PFAM: transporter-associated region; CBS domain containing protein; SMART: CBS domain containing protein; KEGG: ssn:SSON_0612 transporter YP_003037190.1 transfers the fatty acyl group on membrane lipoproteins YP_003037191.1 TIGRFAM: 40-residue YVTN family beta-propeller repeat protein; PFAM: rhomboid family protein; KEGG: ssn:SSON_0610 hypothetical protein YP_003037192.1 PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; KEGG: sfv:SFV_0671 glutamate and aspartate transporter subunit YP_003037193.1 TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: efe:EFER_2449 glutamate and aspartate transporter subunit ; membrane component of ABC superfamily YP_003037194.1 TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: sdy:SDY_0588 glutamate/aspartate transporter permease YP_003037195.1 PFAM: Integrase catalytic region; KEGG: sfv:SFV_3530 IS150 ORF2 YP_003037196.1 KEGG: sfx:S1483 IS103 orf YP_003037197.1 Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific YP_003037198.1 PFAM: heat shock protein 70; KEGG: ssn:SSON_0604 DnaK protein YP_003037199.1 PFAM: protein of unknown function DUF1266; KEGG: sbo:SBO_0509 hypothetical protein YP_003037200.1 PFAM: Sel1 domain protein repeat-containing protein; SMART: Sel1 domain protein repeat-containing protein; KEGG: sdy:SDY_0568 hypothetical protein YP_003037201.1 PFAM: Sel1 domain protein repeat-containing protein; SMART: Sel1 domain protein repeat-containing protein; KEGG: sbc:SbBS512_E0607 hypothetical protein YP_003037202.1 PFAM: protein of unknown function DUF1451; KEGG: ssn:SSON_0597 hypothetical protein YP_003037203.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_003037204.1 rare lipoprotein B; involved in the assembly of LPS in the outer membrane YP_003037205.1 required for the assembly and function of the DNAX complex which is required for the assembly of the subunit beta onto primed DNA YP_003037206.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_003037207.1 PFAM: phosphoglycerate mutase; KEGG: sfv:SFV_0688 phosphohistidine protein PhpB YP_003037208.1 PFAM: Iojap-related protein; KEGG: sbc:SbBS512_E0614 iojap family protein YP_003037209.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_003037210.1 PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain YP_003037211.1 PFAM: cell cycle protein; KEGG: sbc:SbBS512_E0617 rod shape-determining protein RodA YP_003037212.1 PFAM: Rare lipoprotein A; sporulation domain protein; KEGG: ssn:SSON_0587 lipoprotein A YP_003037213.1 penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors YP_003037214.1 PFAM: protein of unknown function DUF493; KEGG: ssn:SSON_0585 hypothetical protein YP_003037215.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system protein H YP_003037216.1 PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: sfv:SFV_0697 DNA-binding transcriptional regulator YP_003037217.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_003037218.1 TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_003037219.1 PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: sbc:SbBS512_E0540 hydrolase, carbon-nitrogen family YP_003037220.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_003037221.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator YP_003037222.1 catalyzes the transfer of palmitate to lipid A YP_003037223.1 responsible for the transport of C4-dicarboxylates during anaerobic growth YP_003037224.1 regulates the expression of citAB in citrate fermentation YP_003037225.1 PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein YP_003037226.1 PFAM: Insertion element protein; KEGG: dps:DP0861 insertion element iso-IS1d protein (InsA) YP_003037227.1 PFAM: IS1 transposase; KEGG: sty:HCM1.136a IS1 transposase YP_003037228.1 TIGRFAM: citrate lyase ligase; cytidyltransferase-related domain protein; PFAM: citrate lyase ligase domain protein; GCN5-related N-acetyltransferase; SMART: citrate lyase ligase domain protein YP_003037229.1 acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate YP_003037230.1 KEGG: sbc:SbBS512_E0530 citrate (pro-3S)-lyase, beta subunit; TIGRFAM: citrate lyase subunit beta; PFAM: HpcH/HpaI aldolase YP_003037231.1 TIGRFAM: citrate lyase subunit alpha; PFAM: citrate lyase subunit alpha YP_003037232.1 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate YP_003037233.1 catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA YP_003037234.1 TIGRFAM: anion transporter; PFAM: sodium/sulfate symporter YP_003037235.1 PFAM: ribonuclease T2 YP_003037236.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation YP_003037237.1 KEGG: sbc:SbBS512_E0523 hypothetical protein YP_003037238.1 PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein YP_003037239.1 PFAM: UspA domain protein; KEGG: sdy:SDY_0542 hypothetical protein YP_003037240.1 TIGRFAM: alkyl hydroperoxide reductase, F subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sbc:SbBS512_E0520 alkyl hydroperoxide reductase subunit F YP_003037241.1 with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate YP_003037242.1 Involved in disulfide bond formation YP_003037243.1 PFAM: Insertion element protein; KEGG: dps:DP0861 insertion element iso-IS1d protein (InsA) YP_003037244.1 PFAM: IS1 transposase; KEGG: sty:HCM1.136a IS1 transposase YP_003037245.1 PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; KEGG: elf:LF82_2590 uncharacterized protein YbdM YP_003037246.1 catalyzes the transfer of an amino moiety YP_003037247.1 member of the iron-containing alcohol dehydrogenase family; unknown function YP_003037248.1 PFAM: protein of unknown function DUF466; KEGG: ssn:SSON_0550 hypothetical protein YP_003037249.1 PFAM: thioesterase superfamily protein; KEGG: sfv:SFV_0545 hypothetical protein YP_003037250.1 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin YP_003037251.1 PFAM: isochorismatase hydrolase; phosphopantetheine-binding; KEGG: sfl:SF0509 2,3-dihydro-2,3-dihydroxybenzoate synthetase, isochroismatase YP_003037252.1 bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate YP_003037253.1 TIGRFAM: isochorismate synthase; PFAM: chorismate binding-like; KEGG: sdy:SDY_0524 isochorismate hydroxymutase 2 YP_003037255.1 with FepCDG is involved in the transport of ferric enterobactin YP_003037256.1 protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters YP_003037257.1 with FepBCG is involved in the transport of ferric enterobactin YP_003037258.1 with FepBCD is involved in the transport of ferric enterobactin YP_003037259.1 with FepBDE is involved in the transport of ferric enterobactin YP_003037260.1 part of the ferric enterobactin transporter; necessary for enetrobactin uptake YP_003037261.1 with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin YP_003037262.1 PFAM: MbtH domain protein YP_003037263.1 PFAM: esterase; KEGG: sbc:SbBS512_E0486 enterochelin esterase YP_003037264.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space YP_003037265.1 PFAM: 4'-phosphopantetheinyl transferase; KEGG: sfv:SFV_0528 phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex YP_003037267.1 PFAM: transposase IS4 family protein YP_003037268.1 PFAM: Hok/gef cell toxic protein; KEGG: sbc:SbBS512_E0481 Hok/Gef family protein YP_003037269.1 PFAM: Insertion element protein; KEGG: dps:DP0861 insertion element iso-IS1d protein (InsA) YP_003037270.1 PFAM: IS1 transposase; KEGG: sty:HCM1.136a IS1 transposase YP_003037271.1 KEGG: sfx:S1483 IS103 orf YP_003037272.1 ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity YP_003037273.1 KEGG: elf:LF82_2587 uncharacterized protein YbdJ YP_003037274.1 PFAM: protein of unknown function DUF419; KEGG: ssn:SSON_0530 hypothetical protein YP_003037275.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive YP_003037276.1 PFAM: MscS Mechanosensitive ion channel; KEGG: ssn:SSON_0528 transport YP_003037277.1 PFAM: amino acid permease-associated region; KEGG: sfv:SFV_0516 phenylalanine transporter YP_003037278.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein YP_003037279.1 with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver YP_003037280.1 KEGG: sfv:SFV_0506 periplasmic copper-binding protein YP_003037281.1 with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver YP_003037282.1 response regulator in two-component regulatory system with CusS; regulates the copper efflux system YP_003037283.1 KEGG: ssn:SSON_0521 sensor kinase CusS; TIGRFAM: heavy metal sensor kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein YP_003037284.1 PFAM: DNA packaging Nu1; KEGG: ssn:SSON_2431 bacteriophage DNA packaging protein YP_003037286.1 PFAM: Bor family protein; KEGG: efe:EFER_2699 lipoprotein; DLP12 prophage YP_003037287.1 PFAM: lysis protein; KEGG: elf:LF82_2080 Rz endopeptidase from lambdoid prophage DLP12 YP_003037288.1 PFAM: glycoside hydrolase family 24 YP_003037289.1 PFAM: Lysis S family protein YP_003037290.1 PFAM: Insertion element protein; KEGG: dps:DP0861 insertion element iso-IS1d protein (InsA) YP_003037291.1 PFAM: IS1 transposase; KEGG: sty:HCM1.136a IS1 transposase YP_003037292.1 PFAM: antitermination Q family protein; KEGG: ssn:SSON_2441 hypothetical protein YP_003037293.1 KEGG: ssn:SSON_2442 hypothetical protein YP_003037294.1 DLP12 prophage; Holliday junction resolvase YP_003037295.1 PFAM: protein of unknown function DUF1364; KEGG: elf:LF82_2577 82 prophage-derived uncharacterized protein YbcO YP_003037296.1 DLP12 prophage; conserved protein similar to phage 82 and lambda proteins YP_003037297.1 DLP12 prophage YP_003037299.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: sfv:SFV_1978 regulator YP_003037300.1 DLP12 prophage; similar to PEBP/RK1P protein family in eukaryotes that inhibits MEK phosphorylation by Raf-1; crystal structure suggests similar properties but exact function is unknown YP_003037301.1 PFAM: Recombinase; Resolvase domain; KEGG: elf:LF82_2573 uncharacterized protein YbcK YP_003037302.1 member of the small MDR (multidrug resistance) family of transporters; in Escherichia coli this protein provides resistance against a number of positively charged compounds including ethidium bromide and erythromycin; proton-dependent secondary transporter which exchanges protons for compound translocation YP_003037304.1 PFAM: zinc finger DksA/TraR C4-type; KEGG: efe:EFER_2731 conserved hypothetical protein from bacteriophage origin; Zn-finger, prokaryotic DksA/TraR C4 type; DnaK suppressor protein YP_003037305.1 KEGG: efe:EFER_2732 conserved hypothetical protein from phage origin YP_003037306.1 KEGG: sek:SSPA2268 excisionase YP_003037307.1 PFAM: integrase; KEGG: sed:SeD_A0603 prophage DLP12 integrase YP_003037308.1 activates the production of the major fimbrae protein FimA YP_003037309.1 PFAM: fimbrial protein; KEGG: ssn:SSON_0507 predicted fimbrial-like adhesin protein YP_003037311.1 PFAM: fimbrial biogenesis outer membrane usher protein YP_003037312.1 PFAM: Pili assembly chaperone, N-terminal; Pili assembly chaperone, C-terminal YP_003037313.1 PFAM: fimbrial protein YP_003037314.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_003037315.1 KEGG: sfv:SFV_0486 hypothetical protein YP_003037316.1 PFAM: membrane-bound metal-dependent hydrolase; KEGG: sbc:SbBS512_E0447 hypothetical protein YP_003037317.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_003037318.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: sfv:SFV_0483 peptidyl-prolyl cis-trans isomerase B (rotamase B) YP_003037319.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine YP_003037320.1 KEGG: sbo:SBO_0420 phosphoribosylaminoimidazole carboxylase; TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase YP_003037321.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_003037322.1 KEGG: ssn:SSON_0497 carbamate kinase; TIGRFAM: carbamate kinase; PFAM: aspartate/glutamate/uridylate kinase YP_003037323.1 KEGG: sbo:SBO_0423 carboxylase YP_003037324.1 PFAM: protein of unknown function DUF1116; KEGG: elf:LF82_3525 uncharacterized protein YlbE YP_003037325.1 multicopy suppressor of dominant negative ftsH mutations YP_003037326.1 TIGRFAM: ureidoglycolate dehydrogenase; PFAM: malate/L-lactate dehydrogenase YP_003037327.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_003037328.1 TIGRFAM: allantoin catabolism protein; PFAM: protein of unknown function DUF861 cupin_3; Cupin 2 conserved barrel domain protein; KEGG: elf:LF82_3524 uncharacterized protein YlbA YP_003037329.1 TIGRFAM: glycerate kinase; PFAM: glycerate kinase YP_003037330.1 PFAM: xanthine/uracil/vitamin C permease YP_003037331.1 Plays a crucial role on both purine and pyrimidine metabolism YP_003037332.1 TIGRFAM: NCS1 nucleoside transporter family; PFAM: permease for cytosine/purines uracil thiamine allantoin YP_003037333.1 TIGRFAM: 2-hydroxy-3-oxopropionate reductase; PFAM: 6-phosphogluconate dehydrogenase NAD-binding YP_003037334.1 TIGRFAM: hydroxypyruvate isomerase; PFAM: Xylose isomerase domain protein TIM barrel YP_003037335.1 catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate YP_003037336.1 regulates operons involved in the utilization of allantoin YP_003037337.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate YP_003037338.1 activator of the allDC-ylbA operon involved in allantoin utilization YP_003037339.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA YP_003037340.1 KEGG: sdy:SDY_0400 hypothetical protein YP_003037341.1 KEGG: sbo:SBO_0403 hypothetical protein YP_003037342.1 PFAM: RHS protein; KEGG: sbo:SBO_0401 protein in rhs element YP_003037344.1 TIGRFAM: hypothetical protein; PFAM: RHS protein; YD repeat-containing protein YP_003037345.1 PFAM: protein of unknown function DUF214; KEGG: ssn:SSON_0485 oxidoreductase YP_003037346.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: sbc:SbBS512_E0430 ABC transporter ATP-binding protein YP_003037347.1 PFAM: lipolytic protein G-D-S-L family; KEGG: efe:EFER_0552 multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1 YP_003037348.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: sbc:SbBS512_E0428 oxidoreductase, short chain dehydrogenase/reductase family YP_003037349.1 PFAM: thioredoxin domain; KEGG: efe:EFER_0550 thioredoxin domain-containing protein YP_003037350.1 PFAM: conserved hypothetical protein; KEGG: ssn:SSON_0480 metal resistance protein YP_003037351.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: sdy:SDY_0409 ABC transporter ATP-binding protein YbbL YP_003037352.1 PFAM: band 7 protein; SMART: band 7 protein; KEGG: sfx:S0441 protease YP_003037353.1 PFAM: protein of unknown function DUF107; KEGG: sbc:SbBS512_E0423 nodulation efficiency family protein YP_003037354.1 activator of copper-responsive regulon genes YP_003037355.1 PFAM: amino acid permease-associated region; Spore germination protein; KEGG: sdy:SDY_0432 amino acid/amine transport protein YP_003037356.1 catalyzes the formation of glutamate from glutamine YP_003037357.1 TIGRFAM: copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase YP_003037358.1 KEGG: sbc:SbBS512_E0418 addiction module antidote protein, HigA family; TIGRFAM: addiction module antidote protein, HigA family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein YP_003037359.1 PFAM: GumN family protein; KEGG: sfv:SFV_0455 ligase YP_003037360.1 TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: sfv:SFV_0454 hypothetical protein YP_003037361.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides YP_003037362.1 PFAM: major facilitator superfamily MFS_1 YP_003037363.1 YbaL; member of the CPA-2 family of antiporters; uncharacterized protein YP_003037364.1 PFAM: PfkB domain protein; KEGG: ssn:SSON_0464 inosine-guanosine kinase YP_003037365.1 PFAM: alpha/beta hydrolase fold-3 domain protein; KEGG: ssn:SSON_0463 acetyl esterase YP_003037366.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_003037367.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_003037368.1 molecular chaperone YP_003037369.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_003037370.1 PFAM: conserved hypothetical protein; KEGG: sea:SeAg_B0530 hypothetical protein YP_003037371.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_003037372.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_003037373.1 PFAM: protein of unknown function DUF454; KEGG: sdy:SDY_0451 hypothetical protein YP_003037374.1 PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks YP_003037375.1 KEGG: sfv:SFV_0439 hypothetical protein YP_003037376.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS YP_003037377.1 regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine YP_003037378.1 TIGRFAM: efflux transporter RND family, MFP subunit; PFAM: secretion protein HlyD YP_003037379.1 TIGRFAM: transporter hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: elf:LF82_0025 acriflavine resistance protein B YP_003037380.1 KEGG: ssn:SSON_0448 hypothetical protein YP_003037381.1 with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins YP_003037382.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: sdy:SDY_0460 maltose O-acetyltransferase YP_003037383.1 KEGG: sdy:SDY_0461 hypothetical protein YP_003037384.1 PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: sfv:SFV_0431 hypothetical protein YP_003037385.1 PFAM: protein of unknown function DUF1428; KEGG: sdy:SDY_0392 hypothetical protein YP_003037386.1 TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; KEGG: ssn:SSON_0442 hypothetical protein YP_003037387.1 KEGG: sbo:SBO_0348 glycoprotein/polysaccharide metabolism YP_003037388.1 TIGRFAM: acyl-CoA thioesterase II; PFAM: acyl-CoA thioesterase; KEGG: ssn:SSON_0440 acyl-CoA thioesterase II YP_003037389.1 TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: ssn:SSON_0439 ammonium transporter YP_003037390.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia. YP_003037391.1 PFAM: ABC transporter; ABC transporter transmembrane region; SMART: ATPase AAA; KEGG: sbo:SBO_0344 multidrug transporter membrane\ATP-binding components YP_003037392.1 PFAM: ABC transporter; ABC transporter transmembrane region; SMART: ATPase AAA; KEGG: sfv:SFV_0422 multidrug transporter membrane\ATP-binding components YP_003037393.1 PFAM: regulatory protein AsnC/Lrp family; SMART: regulatory protein AsnC/Lrp family; KEGG: sbc:SbBS512_E0370 transcriptional regulator, AsnC family YP_003037394.1 TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase type 3; haloacid dehalogenase; sucrose-6F-phosphate phosphohydrolase; KEGG: sbc:SbBS512_E0369 hydrolase Cof YP_003037395.1 PFAM: extracellular solute-binding protein family 5; KEGG: sbc:SbBS512_E0368 bacterial extracellular solute-binding protein, family 5 YP_003037396.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His YP_003037397.1 PFAM: thioesterase superfamily protein; KEGG: sbc:SbBS512_E0366 thioesterase family protein YP_003037398.1 TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; SMART: DNA-binding protein; KEGG: elf:LF82_2555 uncharacterized protein YbaV YP_003037399.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA domain; KEGG: elf:LF82_1706 peptidyl-prolyl cis-trans isomerase D YP_003037400.1 histone-like DNA-binding protein YP_003037401.1 KEGG: elf:LF82_1216 ATP-dependent protease La; TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16; ATPase AAA central domain protein; ATPase associated with various cellular activities AAA_5; SMART: peptidase S16; ATPase AAA YP_003037402.1 PFAM: transposase IS4 family protein YP_003037404.1 binds and unfolds substrates as part of the ClpXP protease YP_003037405.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_003037406.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_003037407.1 KEGG: sdy:SDY_0297 hypothetical protein YP_003037408.1 positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress YP_003037409.1 PFAM: Uncharacterized lipoprotein; KEGG: ssn:SSON_0417 hypothetical protein YP_003037410.1 in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein YP_003037411.1 TIGRFAM: ubiquinol oxidase subunit II; PFAM: COX aromatic rich domain protein; cytochrome C oxidase subunit II; KEGG: sbo:SBO_0326 cytochrome o ubiquinol oxidase subunit II YP_003037412.1 KEGG: ssn:SSON_0414 cytochrome o ubiquinol oxidase subunit I; TIGRFAM: cytochrome o ubiquinol oxidase subunit I; PFAM: cytochrome c oxidase subunit I YP_003037413.1 TIGRFAM: cytochrome o ubiquinol oxidase subunit III; PFAM: cytochrome C oxidase subunit III; KEGG: ssn:SSON_0413 cytochrome o ubiquinol oxidase subunit III YP_003037414.1 TIGRFAM: cytochrome o ubiquinol oxidase subunit IV; PFAM: cytochrome C oxidase subunit IV; KEGG: sbo:SBO_0323 cytochrome o ubiquinol oxidase subunit IV YP_003037415.1 converts protoheme IX and farnesyl diphosphate to heme O YP_003037416.1 PFAM: protein of unknown function DUF1778; KEGG: ssn:SSON_0410 hypothetical protein YP_003037417.1 PFAM: GCN5-related N-acetyltransferase; KEGG: ssn:SSON_0409 acetyltransferase YP_003037418.1 PFAM: Sel1 domain protein repeat-containing protein; SMART: Sel1 domain protein repeat-containing protein; KEGG: sfv:SFV_0396 hypothetical protein YP_003037419.1 PFAM: major facilitator superfamily MFS_1; KEGG: ssn:SSON_0404 transporter YP_003037420.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_003037421.1 Ketopantoate reductase; catalyzes the NADPH reduction of Ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis YP_003037422.1 TIGRFAM: DJ-1 family protein; PFAM: ThiJ/PfpI domain protein; KEGG: sbc:SbBS512_E0346 protein ThiJ YP_003037423.1 Required for the synthesis of the thiazole moiety YP_003037424.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_003037425.1 PFAM: polyprenyl synthetase; KEGG: sdy:SDY_0309 geranyltranstransferase YP_003037426.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_003037427.1 PFAM: aldo/keto reductase YP_003037428.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate YP_003037429.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP YP_003037430.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_003037431.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; subunit beta of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_003037432.1 riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil YP_003037433.1 PFAM: ATP-cone domain protein; KEGG: ssn:SSON_0390 hypothetical protein YP_003037434.1 KEGG: ssn:SSON_0389 hypothetical protein YP_003037435.1 PFAM: nucleoside-specific channel-forming protein Tsx; KEGG: sfv:SFV_0376 outer membrane protein Tsx YP_003037436.1 PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: ssn:SSON_0387 hypothetical protein YP_003037437.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_003037438.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_003037439.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_003037440.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_003037441.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_003037442.1 Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP YP_003037443.1 PFAM: alpha amylase catalytic region; glycoside hydrolase family 13 domain protein Ig domain protein region domain protein; SMART: alpha amylase catalytic sub domain; KEGG: ssn:SSON_0380 maltodextrin glucosidase YP_003037444.1 cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation YP_003037445.1 TIGRFAM: branched-chain amino acid transporter II carrier protein; PFAM: branched-chain amino acid transporter II carrier protein; KEGG: sdy:SDY_0336 branched chain amino acid transporter II carrier protein YP_003037446.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB YP_003037447.1 two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB YP_003037448.1 with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity YP_003037449.1 with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity YP_003037450.1 member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers YP_003037452.1 catalyzes phosphorylation of fructose; cytosolic enzyme YP_003037453.1 PFAM: exonuclease RdgC; KEGG: cko:CKO_02778 recombination associated protein YP_003037454.1 PFAM: Insertion element protein; KEGG: hdu:HD1971 insertion element IS1 1/2/3/5/6 protein InsA YP_003037455.1 PFAM: IS1 transposase; KEGG: sty:HCM1.136a IS1 transposase YP_003037457.1 KEGG: sbc:SbBS512_E0309 hypothetical protein YP_003037458.1 PFAM: protein of unknown function DUF1255; KEGG: ssn:SSON_0367 hypothetical protein YP_003037459.1 PFAM: AroM family protein; KEGG: sbc:SbBS512_E0307 AroM protein YP_003037460.1 KEGG: ssn:SSON_0365 hypothetical protein YP_003037461.1 type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_003037462.1 PFAM: protein of unknown function DUF188; KEGG: sdy:SDY_0357 hypothetical protein YP_003037463.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_003037464.1 catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis YP_003037465.1 PFAM: PsiF repeat protein; KEGG: ssn:SSON_0359 hypothetical protein YP_003037466.1 KEGG: sbo:SBO_0278 bacterial alkaline phosphatase; PFAM: alkaline phosphatase; SMART: alkaline phosphatase YP_003037467.1 KEGG: ssn:SSON_0357 hypothetical protein YP_003037468.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_003037469.1 KEGG: sdy:SDY_0366 hypothetical protein YP_003037470.1 KEGG: sbc:SbBS512_E0296 hypothetical protein YP_003037471.1 PFAM: protein of unknown function DUF1615; KEGG: elf:LF82_2531 uncharacterized protein YaiW YP_003037472.1 in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope YP_003037474.1 this protein has no known enzymatic function YP_003037475.1 KEGG: ssn:SSON_0350 DNA-binding transcriptional regulator YP_003037476.1 TIGRFAM: outer membrane autotransporter barrel domain protein; PFAM: Autotransporter beta- domain protein; Pertactin; KEGG: stm:STM0373 flagellar protein YP_003037477.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_003037478.1 catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers YP_003037479.1 PFAM: binding-protein-dependent transporters inner membrane component; KEGG: elf:LF82_2227 taurine transporter permease protein TauC YP_003037480.1 Part of the ABC transporter complex tauABC involved in taurine import YP_003037481.1 with TauB and TauC is responsible for taurine uptake. YP_003037482.1 PFAM: Insertion element protein; KEGG: dps:DP0861 insertion element iso-IS1d protein (InsA) YP_003037483.1 PFAM: IS1 transposase; KEGG: sty:HCM1.136a IS1 transposase YP_003037484.1 KEGG: ssn:SSON_0337 hypothetical protein YP_003037485.1 formaldehyde-induced negative regulator of the frmRAB operon YP_003037486.1 TIGRFAM: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: sbc:SbBS512_E0271 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase YP_003037487.1 KEGG: ssn:SSON_0334 esterase; TIGRFAM: S-formylglutathione hydrolase; PFAM: esterase YP_003037489.1 TIGRFAM: benzoate transport; PFAM: major facilitator superfamily MFS_1; general substrate transporter YP_003037490.1 catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate YP_003037491.1 catalyzes the formation of acetyl-CoA from acetalaldehyde YP_003037492.1 catalyzes the formation of 2-keto-4-hydroxypentanoic acid from 2-hydroxypentadienoic acid YP_003037493.1 PFAM: alpha/beta hydrolase fold YP_003037494.1 catalyzes the cleavage of 3-(2,3-dihydroxyphenyl) propionate into 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate; part of the 3-phenylpropionic acid degradation pathway; member of the protocatechuate 4,5-dioxygenase family YP_003037495.1 catalyzes the formation of 3-(2,3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate YP_003037496.1 activator of 3-phenylpropionic acid catabolism YP_003037497.1 transcriptional repressor of lac operon; forms a homotetramer as a dimer of dimers; binds specific sites in lac operon resulting in DNA looping between the operators; binds allolactose as inducer YP_003037498.1 forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon YP_003037499.1 lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments YP_003037500.1 transfers acetyl group from acetyl-CoA to the 6-hydroxyl of galactopyranosides; exact physiological role is unknown YP_003037501.1 MFS transporter family member induced in the presence of cyanate as part of a 3 gene operon; not essential YP_003037502.1 catalyzes the reaction of cyanate and bicarbonate to produce ammonia and carbon dioxide YP_003037503.1 PFAM: carbonic anhydrase YP_003037504.1 controls the expression of the cynTSX operon involved in degrading and using cyanate as a sole nitrogen source YP_003037505.1 Catalyzes the deamination of cytosine to uracil and ammonia YP_003037506.1 TIGRFAM: NCS1 nucleoside transporter family; PFAM: permease for cytosine/purines uracil thiamine allantoin YP_003037507.1 catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent YP_003037508.1 functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C YP_003037509.1 catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity YP_003037510.1 KEGG: hypothetical protein YP_003037511.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate YP_003037512.1 TIGRFAM: propionate catabolism operon regulatory protein PrpR; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; Propionate catabolism activator domain protein; SMART: ATPase AAA YP_003037513.1 PFAM: protein of unknown function DUF1471 YP_003037514.1 TIGRFAM: homoserine/threonine efflux pump; PFAM: lysine exporter protein (LYSE/YGGA) YP_003037515.1 KEGG: ssn:SSON_0303 hypothetical protein YP_003037516.1 KEGG: ssn:SSON_0306 hypothetical protein YP_003037517.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein YP_003037518.1 metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain YP_003037519.1 PFAM: aspartate/glutamate/uridylate kinase; KEGG: elf:LF82_2518 carbamate kinase-like protein YahI YP_003037520.1 KEGG: hypothetical protein YP_003037521.1 PFAM: protein of unknown function DUF1116; KEGG: elf:LF82_2517 uncharacterized protein YahG YP_003037522.1 PFAM: FdrA family protein; KEGG: ssn:SSON_0312 oxidoreductase subunit YP_003037523.1 KEGG: ssn:SSON_0313 hypothetical protein YP_003037524.1 PFAM: ankyrin YP_003037525.1 PFAM: protein of unknown function DUF1097 YP_003037526.1 PFAM: LysR substrate-binding; regulatory protein LysR YP_003037527.1 PFAM: EAL domain protein; regulatory protein LuxR; SMART: EAL domain protein; regulatory protein LuxR; KEGG: elf:LF82_2511 uncharacterized protein YahA YP_003037529.1 proton-motive-force-driven choline transporter YP_003037530.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes YP_003037531.1 catalyzes the formation of betaine from betaine aldehyde YP_003037532.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine YP_003037533.1 KEGG: sfv:SFV_0321 hypothetical protein YP_003037534.1 PFAM: protein of unknown function DUF162; KEGG: sbc:SbBS512_E0257 hypothetical protein YP_003037535.1 TIGRFAM: iron-sulfur cluster binding protein; PFAM: protein of unknown function DUF162; KEGG: sfv:SFV_0318 hypothetical protein YP_003037536.1 PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: ssn:SSON_0318 dehydrogenase subunit YP_003037538.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type YP_003037539.1 Involved in disulfide oxidoreductase activity and electron transport YP_003037540.1 PFAM: protein of unknown function DUF1471 YP_003037541.1 PFAM: protein of unknown function DUF417; KEGG: ssn:SSON_0322 hypothetical protein YP_003037542.1 PFAM: transcription activator effector binding; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: elf:LF82_3510 uncharacterized HTH-type transcriptional regulator YP_003037543.1 KEGG: elf:LF82_p054 adhesin YP_003037545.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_003037546.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif YP_003037548.1 PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; KEGG: sbo:SBO_0225 regulator YP_003037549.1 KEGG: sbo:SBO_0226 hypothetical protein YP_003037550.1 KEGG: sbo:SBO_0227 hypothetical protein YP_003037552.1 KEGG: elf:LF82_2509 uncharacterized protein YagW YP_003037554.1 PFAM: protein of unknown function UPF0153; KEGG: elf:LF82_3519 uncharacterized protein YkgJ YP_003037555.1 PFAM: protein of unknown function DUF1440 YP_003037556.1 PFAM: [2Fe-2S]-binding domain protein; ferredoxin; KEGG: esa:ESA_04143 hypothetical protein YP_003037557.1 PFAM: molybdopterin dehydrogenase FAD-binding YP_003037558.1 PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead YP_003037559.1 PFAM: protein of unknown function DUF182; KEGG: esa:ESA_04147 hypothetical protein YP_003037560.1 KEGG: smd:Smed_5891 LysR family transcriptional regulator YP_003037561.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_003037562.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_003037563.1 PFAM: porin Gram-negative type; KEGG: sbo:SBO_0247 outer membrane phosphoporin protein E YP_003037564.1 PFAM: IS1 transposase YP_003037565.1 PFAM: Insertion element protein; KEGG: hdu:HD1971 insertion element IS1 1/2/3/5/6 protein InsA YP_003037566.1 involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS YP_003037567.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation YP_003037568.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively YP_003037569.1 KEGG: sbc:SbBS512_E0234 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase dimerisation domain protein; peptidase M20 YP_003037570.1 similar to release factor 1 and 2 YP_003037571.1 KEGG: sdy:SDY_0482 hypothetical protein YP_003037572.1 PFAM: GCN5-related N-acetyltransferase; KEGG: efe:EFER_2746 acyltransferase with acyl-CoA N-acyltransferase domain YP_003037573.1 YafO overproduction induces toxicity; it is believed to be the toxin of a toxin-antitoxin pair; unknown function YP_003037574.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172; KEGG: efe:EFER_2748 antitoxin of the YafO-YafN toxin-antitoxin system YP_003037575.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_003037576.1 PFAM: OmpA/MotB domain protein; KEGG: ssn:SSON_0272 hypothetical protein YP_003037577.1 PFAM: type III secretion FHIPEP protein; KEGG: ssn:SSON_0273 flagellar biosynthesis YP_003037578.1 KEGG: ssn:SSON_0271 hypothetical protein YP_003037579.1 PFAM: NLP/P60 protein; KEGG: ssn:SSON_0269 lipoprotein YP_003037581.1 TIGRFAM: addiction module antitoxin, RelB/DinJ family; PFAM: RelB antitoxin; KEGG: ssn:SSON_0268 damage-inducible protein J YP_003037582.1 TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; KEGG: sdy:SDY_0251 hypothetical protein YP_003037583.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: ssn:SSON_0266 hypothetical protein YP_003037584.1 PFAM: glutamine amidotransferase class-II; KEGG: sfv:SFV_0305 amidotransferase YP_003037585.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate YP_003037586.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_003037587.1 inactivates vertebrate C-type lysozyme YP_003037588.1 PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: sbc:SbBS512_E0215 hydrolase, carbon-nitrogen family YP_003037589.1 PFAM: transposase IS4 family protein; KEGG: ssn:SSON_0260 receptor YP_003037590.1 KEGG: sea:SeAg_B4436 hypothetical protein YP_003037591.1 PFAM: IS1 transposase YP_003037592.1 PFAM: Insertion element protein; KEGG: hdu:HD1971 insertion element IS1 1/2/3/5/6 protein InsA YP_003037593.1 KEGG: ssn:SSON_0231 aminopeptidase YP_003037594.1 3'-5' exonuclease of DNA polymerase III YP_003037595.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_003037596.1 PFAM: methyltransferase type 11; KEGG: sbc:SbBS512_E0210 methyltransferase YP_003037597.1 catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione YP_003037598.1 catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall YP_003037599.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: sbc:SbBS512_E0206 methyltransferase, UbiE/COQ5 family YP_003037600.1 PFAM: endonuclease/exonuclease/phosphatase; KEGG: sbc:SbBS512_E0205 endonuclease/exonuclease/phosphatase family protein YP_003037601.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: ssn:SSON_0222 transcriptional regulator LysR-type YP_003037602.1 catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid YP_003037603.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate YP_003037604.1 part of the metNIQ transporter for methionine YP_003037605.1 part of the MetNIQ methionine uptake system YP_003037606.1 TIGRFAM: lipoprotein, YaeC family; PFAM: NLPA lipoprotein; KEGG: sbc:SbBS512_E0191 D-methionine ABC transporter periplasmic D-methionine-binding lipoprotein YP_003037607.1 KEGG: sdy:SDY_0215 outer membrane lipoprotein YP_003037608.1 PFAM: protein of unknown function UPF0066; KEGG: ssn:SSON_0209 hypothetical protein YP_003037609.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_003037610.1 KEGG: sbc:SbBS512_E0187 lipoprotein YP_003037611.1 PFAM: copper resistance lipoprotein NlpE; KEGG: sbc:SbBS512_E0186 copper homeostasis protein CutF YP_003037612.1 PFAM: class I peptide chain release factor; KEGG: sbc:SbBS512_E0185 peptidyl-tRNA hydrolase domain protein YP_003037613.1 PFAM: YaeQ family protein; KEGG: sfv:SFV_0174 hypothetical protein YP_003037614.1 PFAM: protein of unknown function UPF0253; KEGG: sdy:SDY_0208 hypothetical protein YP_003037615.1 Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination YP_003037616.1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase YP_003037617.1 PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sbc:SbBS512_E0180 glyoxylase family protein YP_003037618.1 PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; KEGG: ssn:SSON_0199 lysine decarboxylase 2, constitutive YP_003037619.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_003037620.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_003037621.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_003037622.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_003037623.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_003037624.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_003037625.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_003037626.1 PFAM: outer membrane chaperone Skp (OmpH); KEGG: ssn:SSON_0190 periplasmic chaperone YP_003037627.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins YP_003037628.1 catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response YP_003037629.1 catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate YP_003037630.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate YP_003037631.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_003037632.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_003037633.1 Catalyzes the phosphorylation of UMP to UDP YP_003037634.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_003037635.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_003037636.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_003037637.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_003037638.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_003037639.1 PFAM: metallophosphoesterase; KEGG: sbo:SBO_0153 phosphodiesterase YaeI YP_003037640.1 KEGG: ssn:SSON_0176 structural protein YP_003037641.1 regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization YP_003037642.1 protease Do; required at high temperature; degrades damaged proteins YP_003037643.1 forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate YP_003037644.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_003037645.1 solute binding component of the vitamin B12 transport system BtuCDF YP_003037646.1 PFAM: protein of unknown function UPF0126; KEGG: sbc:SbBS512_E0149 hypothetical protein YP_003037647.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors YP_003037648.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation YP_003037649.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_003037650.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome YP_003037651.1 Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores YP_003037652.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter YP_003037653.1 PFAM: transposase IS4 family protein; KEGG: seh:SeHA_C4716 transposase (IS4 family) YP_003037654.1 bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell YP_003037655.1 similar in sequence to the ATP-dependent RNA helicase HrpA YP_003037656.1 TIGRFAM: 2'-5' RNA ligase; PFAM: phosphoesterase HXTX; KEGG: ssn:SSON_0159 hypothetical protein YP_003037657.1 Regulatory factor involved in maltose metabolism YP_003037658.1 TIGRFAM: RNA polymerase-binding protein DksA; PFAM: zinc finger DksA/TraR C4-type; KEGG: sdy:SDY_0161 DnaK transcriptional regulator DksA YP_003037659.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu YP_003037660.1 polymerase that creates the 3' poly(A) tail found in some mRNA's YP_003037661.1 catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP YP_003037662.1 PFAM: fimbrial protein; KEGG: ssn:SSON_0153 fimbrial-like protein YP_003037663.1 PFAM: Pili assembly chaperone, N-terminal; Pili assembly chaperone, C-terminal; KEGG: sbo:SBO_0126 chaperone protein EcpD YP_003037664.1 similar to the fimbrial usher protein PapC YP_003037665.1 KEGG: efe:EFER_0160 fimbrial-like adhesin exported protein YP_003037666.1 PFAM: fimbrial protein; KEGG: ssn:SSON_0146 fimbrial protein YP_003037667.1 KEGG: ssn:SSON_0145 fimbrial protein YP_003037668.1 PFAM: fimbrial protein; KEGG: elf:LF82_2474 uncharacterized fimbrial-like protein YadC YP_003037669.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_003037670.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_003037671.1 PFAM: transposase YhgA family protein; KEGG: sfv:SFV_0122 hypothetical protein YP_003037672.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_003037673.1 PFAM: polysaccharide deacetylase; KEGG: ssn:SSON_0138 hypothetical protein YP_003037674.1 PFAM: PTS system fructose subfamily IIA component; KEGG: sbc:SbBS512_E0122 PTS system IIA component domain protein YP_003037675.1 PFAM: ABC transporter; KEGG: ssn:SSON_0136 hypothetical protein YP_003037676.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: ssn:SSON_0135 ATP-binding component of a transporter YP_003037677.1 catalyzes the interconversion of bicarbonate and carbon dioxide YP_003037678.1 KEGG: sfv:SFV_0116 hypoxanthine-guanine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase YP_003037679.1 TIGRFAM: membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; PFAM: pyrrolo-quinoline quinone; SMART: pyrrolo-quinoline quinone YP_003037680.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification YP_003037681.1 KEGG: ssn:SSON_0130 hypothetical protein YP_003037682.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_003037683.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine YP_003037684.1 PFAM: conserved hypothetical protein; KEGG: ssn:SSON_0127 hypothetical protein YP_003037685.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_003037686.1 KEGG: sbc:SbBS512_E0110 hypothetical protein YP_003037687.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_003037688.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains YP_003037689.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_003037690.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex YP_003037691.1 PFAM: amino acid permease-associated region; KEGG: efe:EFER_0132 aromatic amino acid transporter YP_003037692.1 involved in regulation of beta-lactamase; signaling protein YP_003037693.1 PFAM: N-acetylmuramoyl-L-alanine amidase family 2; SMART: N-acetylmuramoyl-L-alanine amidase family 2 YP_003037694.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide YP_003037695.1 KEGG: ssn:SSON_0116 major pilin subunit YP_003037696.1 PFAM: type II secretion system protein E YP_003037697.1 PFAM: type II secretion system protein; KEGG: sbc:SbBS512_E0098 type IV pilus assembly protein PilC YP_003037698.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate YP_003037699.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_003037700.1 PFAM: protein of unknown function DUF1342; KEGG: ssn:SSON_0110 hypothetical protein YP_003037701.1 PFAM: protein of unknown function DUF329; KEGG: ssn:SSON_0109 zinc-binding protein YP_003037702.1 TIGRFAM: mutator MutT protein; PFAM: NUDIX hydrolase; KEGG: ssn:SSON_0107 nucleoside triphosphate pyrophosphohydrolase, marked preference for dGTP YP_003037703.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_003037704.1 secM translational pause allows for the initiation of secA translation YP_003037705.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_003037706.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_003037707.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane YP_003037708.1 involved in septum formation YP_003037709.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_003037710.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_003037711.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_003037712.1 integral membrane protein involved in stabilizing FstZ ring during cell division YP_003037713.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_003037714.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_003037715.1 TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; KEGG: ssn:SSON_0094 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase YP_003037716.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_003037717.1 PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: sdy:SDY_0114 penicillin-binding protein 3 YP_003037718.1 membrane bound cell division protein at septum containing leucine zipper motif YP_003037719.1 TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; KEGG: sbc:SbBS512_E0075 S-adenosyl-methyltransferase MraW YP_003037720.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_003037721.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism YP_003037722.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_003037723.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive YP_003037724.1 activator for leuABCD operon; member of LysR family of transcriptional activators YP_003037725.1 involved in attenuation control of the leuABCD operon in leucine biosynthesis YP_003037726.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_003037727.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_003037728.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_003037729.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_003037730.1 TIGRFAM: sugar efflux transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sfx:S0067 transporter YP_003037731.1 KEGG: cko:CKO_03311 hypothetical protein YP_003037732.1 activates sgrS under glucose-phosphate stress conditions YP_003037733.1 part of the thiamine and TPP transporter tbpA-thiPQ YP_003037734.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine YP_003037735.1 with TbpA and ThiP is part of the thiamine and TPP transporter YP_003037736.1 PFAM: SNARE associated Golgi protein; KEGG: sbo:SBO_0052 hypothetical protein YP_003037737.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose YP_003037738.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate YP_003037739.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism YP_003037740.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_003037741.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C YP_003037742.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA YP_003037743.1 catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs YP_003037744.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system YP_003037745.1 determines N-hexane tolerance and is involved in outer membrane permeability YP_003037746.1 Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB YP_003037747.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_003037748.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_003037749.1 protein associated with Co2+ and Mg2+ efflux YP_003037750.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_003037751.1 catalyzes the reduction of dihydrofolate to tetrahydrofolate YP_003037752.1 transporter that facilitates potassium-efflux YP_003037753.1 Required for full activity of KefC, a potassium-proton antiporter YP_003037754.1 PFAM: major facilitator superfamily MFS_1; general substrate transporter YP_003037755.1 KEGG: ssn:SSON_0052 ferredoxin YP_003037756.1 FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction YP_003037757.1 involved in electron transfer during carnitine metabolism YP_003037758.1 required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase YP_003037759.1 catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism YP_003037760.1 catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA YP_003037761.1 PFAM: AMP-dependent synthetase and ligase; KEGG: ssn:SSON_0043 crotonobetaine/carnitine-CoA ligase YP_003037762.1 catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA YP_003037763.1 involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities YP_003037764.1 regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons YP_003037765.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_003037766.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_003037767.1 KEGG: spq:SPAB_00081 hypothetical protein YP_003037768.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_003037769.1 catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides YP_003037770.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_003037771.1 PFAM: peptidylprolyl isomerase FKBP-type; KEGG: ssn:SSON_0033 probable FKBX-type 16KD peptidyl-prolyl cis-trans isomerase YP_003037772.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_003037773.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_003037774.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_003037775.1 KEGG: sdy:SDY_0046 hypothetical protein YP_003037776.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_003037777.1 PFAM: IS1 transposase; KEGG: sty:HCM1.136a IS1 transposase YP_003037778.1 PFAM: Insertion element protein; KEGG: hdu:HD1971 insertion element IS1 1/2/3/5/6 protein InsA YP_003037779.1 KEGG: ssn:SSON_0023 hypothetical protein YP_003037780.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC YP_003037781.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_003037782.1 PFAM: Hok/gef cell toxic protein; KEGG: ssn:SSON_0016 Gef protein interferes with membrane function when in excess YP_003037784.1 PFAM: transposase IS4 family protein YP_003037785.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_003037786.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_003037787.1 KEGG: ssn:SSON_0013 hypothetical protein YP_003037788.1 PFAM: protein of unknown function UPF0174; KEGG: ssn:SSON_0012 hypothetical protein YP_003037789.1 PFAM: GPR1/FUN34/yaaH family protein; KEGG: ssn:SSON_0011 hypothetical protein YP_003037790.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis YP_003037791.1 KEGG: sbc:SbBS512_E0008 transaldolase; TIGRFAM: transaldolase; PFAM: transaldolase YP_003037792.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: elf:LF82_2462 uncharacterized transporter YaaJ YP_003037793.1 PFAM: protein of unknown function DUF328; KEGG: sdy:SDY_0006 hypothetical protein YP_003037794.1 KEGG: ssn:SSON_0005 hypothetical protein YP_003037795.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_003037796.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_003037797.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_003037798.1 member of the SPOUT superfamily of methyltransferases YP_003037799.1 KEGG: sfx:S4705 hypothetical protein YP_003037800.1 PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; KEGG: sfv:SFV_4435 two-component response regulator YP_003037801.1 PFAM: inner membrane protein CreD; KEGG: sbc:SbBS512_E4948 inner membrane protein CreD YP_003037802.1 part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation YP_003037803.1 response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation YP_003037804.1 PFAM: CreA family protein; KEGG: sfv:SFV_4431 hypothetical protein YP_003037805.1 PFAM: transcription activator effector binding; helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: sfv:SFV_4430 right origin-binding protein YP_003037806.1 catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate YP_003037807.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog YP_003037808.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription YP_003037809.1 catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan YP_003037810.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_003037811.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide YP_003037812.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_003037813.1 catalyzes the formation of serine from O-phosphoserine YP_003037814.1 KEGG: sbo:SBO_4450 hypothetical protein YP_003037815.1 Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins YP_003037816.1 PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; KEGG: sfv:SFV_4419 hypothetical protein YP_003037817.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_003037818.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_003037819.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate YP_003037820.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_003037822.1 PFAM: radical SAM protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sfv:SFV_4413 activating enzyme YP_003037823.1 PFAM: TatD-related deoxyribonuclease; KEGG: elf:LF82_3504 uncharacterized deoxyribonuclease YjjV YP_003037824.1 PFAM: patatin; KEGG: ssn:SSON_4528 hypothetical protein YP_003037825.1 PFAM: protein of unknown function DUF1328; KEGG: sbc:SbBS512_E4920 hypothetical protein YP_003037826.1 PFAM: transport-associated; SMART: transport-associated and nodulation region; KEGG: ssn:SSON_4526 periplasmic protein YP_003037827.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_003037828.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily YP_003037829.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18 YP_003037830.1 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_003037831.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit YP_003037832.1 PFAM: protein of unknown function DUF1435; KEGG: sfv:SFV_4401 inner membrane protein YP_003037833.1 PFAM: ferric iron reductase; KEGG: sbo:SBO_4427 ferric iron reductase involved in ferric hydroximate transport YP_003037834.1 regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin YP_003037835.1 PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR YP_003037836.1 PFAM: protein of unknown function DUF1212; KEGG: sfv:SFV_4395 structural protein YP_003037837.1 KEGG: sfv:SFV_4394 hypothetical protein YP_003037838.1 This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N' YP_003037839.1 acts to load the DnaB helicase onto the initiation site during DNA replication YP_003037840.1 KEGG: sbc:SbBS512_E4900 hypothetical protein YP_003037841.1 catalyzes the transfer of phosphoglycerol to the glucan backbone YP_003037842.1 PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: ssn:SSON_4504 oxidoreductase YP_003037843.1 PFAM: major facilitator superfamily MFS_1 YP_003037844.1 PFAM: chemotaxis sensory transducer; ligand binding Tar domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; ligand binding Tar domain protein; KEGG: sbo:SBO_4414 methyl-accepting chemotaxis protein I YP_003037845.1 KEGG: sfv:SFV_4385 regulator of the 4HPA-hydroxylase operon; TIGRFAM: homoprotocatechuate degradation operon regulator, HpaR; PFAM: regulatory protein MarR; SMART: regulatory protein MarR YP_003037846.1 KEGG: sbo:SBO_4412 5-oxo-1,2,5-tricarboxilic-3-penten acid decarboxilase/isomerase; TIGRFAM: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, HpaG1 subunit; 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase,HpaG2 subunit; PFAM: fumarylacetoacetate hydrolase YP_003037847.1 TIGRFAM: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: sbc:SbBS512_E4889 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase YP_003037848.1 KEGG: sbc:SbBS512_E4888 3,4-dihydroxyphenylacetate 2,3-dioxygenase; TIGRFAM: 3,4-dihydroxyphenylacetate 2,3-dioxygenase; PFAM: extradiol ring-cleavage dioxygenase class III protein subunit B YP_003037849.1 PFAM: 5-carboxymethyl-2-hydroxymuconate isomerase; KEGG: sfx:S4651 5-carboxymethyl-2-hydroxymuconate delta-isomerase YP_003037850.1 KEGG: ssn:SSON_4495 2-oxo-hept-3-ene-1,7-dioate hydratase; TIGRFAM: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase; PFAM: fumarylacetoacetate hydrolase YP_003037851.1 KEGG: ssn:SSON_4494 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase (HHED aldolase); TIGRFAM: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; PFAM: HpcH/HpaI aldolase YP_003037852.1 TIGRFAM: 4-hydroxyphenylacetate transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sbo:SBO_4406 4-hydroxyphenylacetate permease YP_003037853.1 KEGG: efe:EFER_3069 regulator of the 4HPA-hydroxylase operon; TIGRFAM: 4-hydroxyphenylacetate catabolism regulatory protein HpaA; PFAM: helix-turn-helix- domain containing protein AraC type; Cupin 2 conserved barrel domain protein; SMART: helix-turn-helix- domain containing protein AraC type YP_003037854.1 TIGRFAM: 4-hydroxyphenylacetate 3-monooxygenase, oxygenase subunit; PFAM: 4-hydroxyphenylacetate 3-hydroxylase; KEGG: efe:EFER_3070 4-hydroxyphenylacetate 3-monooxygenase large component YP_003037855.1 TIGRFAM: 4-hydroxyphenylacetate 3-monooxygenase, reductase subunit; PFAM: flavin reductase domain protein FMN-binding; KEGG: sbc:SbBS512_E4881 4-hydroxyphenylacetate 3-monooxygenase, reductase component YP_003037856.1 PFAM: carbon starvation protein CstA; KEGG: sbc:SbBS512_E4880 carbon starvation family protein YP_003037857.1 PFAM: protein of unknown function DUF466; KEGG: sfv:SFV_4372 hypothetical protein YP_003037858.1 PFAM: cobalamin synthesis protein P47K; cobalamin synthesis CobW domain protein; KEGG: efe:EFER_3075 GTPase YP_003037859.1 PFAM: restriction endonuclease; KEGG: ypb:YPTS_4095 restriction endonuclease YP_003037860.1 restriction endonuclease; the EcoKI enzyme recognizes 5'-AACN(6)GTGC-3'; subunit R is required for both nuclease and ATPase activities YP_003037861.1 PFAM: N-6 DNA methylase; KEGG: efe:EFER_3080 DNA methylase M YP_003037862.1 PFAM: Insertion element protein; KEGG: hdu:HD1971 insertion element IS1 1/2/3/5/6 protein InsA YP_003037863.1 PFAM: IS1 transposase; KEGG: sty:HCM1.136a IS1 transposase YP_003037864.1 involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response YP_003037865.1 McrB protein together with McrC forms the McrBC restriction system; recognizes N4- and C5-methylcytosine (and 5-hydroxy-methylcytosines); appears to act against 5-methylcytosine preceded by a purine residue YP_003037866.1 McrC protein together with McrB forms the McrBC restriction system; recognizes N4- and C5-methylcytosine (and 5-hydroxy-methylcytosines); appears to act against 5-methylcytosine preceded by a purine residue; MrcC modulates the specificty of McrB and has DNA cleavage activity YP_003037867.1 PFAM: IS1 transposase; KEGG: dps:DP0860 insertion element IS1 1/5/6 protein (InsB) YP_003037868.1 PFAM: Insertion element protein; KEGG: hdu:HD1971 insertion element IS1 1/2/3/5/6 protein InsA YP_003037869.1 PFAM: transposase YhgA family protein; KEGG: efe:EFER_3089 conserved hypothetical protein, transposase YP_003037871.1 PFAM: major facilitator superfamily MFS_1; KEGG: sbc:SbBS512_E4767 multidrug resistance protein MdtM YP_003037872.1 PFAM: protein of unknown function DUF445; KEGG: sbc:SbBS512_E4768 putatitve membrane protein YP_003037873.1 PFAM: 2-hydroxyglutaryl-CoA dehydratase D-component; KEGG: elf:LF82_3487 uncharacterized protein YjiM YP_003037874.1 KEGG: sbc:SbBS512_E4770 (R)-2-hydroxyglutaryl-CoA dehydratase activator; TIGRFAM: CoA-substrate-specific enzyme activase; PFAM: ATPase BadF/BadG/BcrA/BcrD type YP_003037875.1 KEGG: sbo:SBO_4385 hypothetical protein YP_003037876.1 PFAM: SdiA-regulated domain protein; KEGG: sbo:SBO_4384 hypothetical protein YP_003037877.1 PFAM: protein of unknown function DUF1228; major facilitator superfamily MFS_1; KEGG: elf:LF82_3484 uncharacterized protein YjiJ YP_003037878.1 in yeast cells this enzyme removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate; functions in tRNA splicing; the function and substrate of bacterial enzymes in organisms that do not perform splicing is unknown YP_003037879.1 PFAM: nucleoside recognition domain protein; KEGG: sbc:SbBS512_E4775 transporter YP_003037880.1 PFAM: nucleoside recognition domain protein; KEGG: sbo:SBO_4380 hypothetical protein YP_003037881.1 TIGRFAM: isoaspartyl dipeptidase; PFAM: amidohydrolase; amidohydrolase; KEGG: sbc:SbBS512_E4777 beta-aspartyl peptidase YP_003037882.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: elf:LF82_3481 uncharacterized HTH-type transcriptional regulator YP_003037883.1 inhibitor of RssB activity in response to DNA damage; blocks degradation of stationary phase sigma factor RpoS YP_003037885.1 KEGG: sbc:SbBS512_E4782 hypothetical protein YP_003037887.1 KEGG: ssn:SSON_4480 hypothetical protein YP_003037888.1 regulates the expression of uxuBA YP_003037889.1 KEGG: sbc:SbBS512_E4790 hypothetical protein YP_003037890.1 PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: ssn:SSON_4478 D-mannonate oxidoreductase YP_003037891.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate YP_003037892.1 TIGRFAM: gluconate transporter; PFAM: gluconate transporter; citrate transporter YP_003037893.1 PFAM: FimH mannose-binding domain protein; fimbrial protein; KEGG: sfv:SFV_4206 FimH protein precursor YP_003037894.1 PFAM: fimbrial protein; KEGG: sfv:SFV_4207 minor fimbrial subunit, precursor polypeptide YP_003037895.1 PFAM: fimbrial protein YP_003037896.1 PFAM: fimbrial biogenesis outer membrane usher protein YP_003037897.1 PFAM: Pili assembly chaperone, N-terminal; Pili assembly chaperone, C-terminal; KEGG: sfx:S4463 periplasmic chaperone YP_003037898.1 PFAM: fimbrial protein; KEGG: sfx:S4464 fimbrial protein YP_003037899.1 PFAM: fimbrial protein; KEGG: sbo:SBO_4364 major type 1 subunit fimbrin YP_003037900.1 inversion of on/off regulator of fimA YP_003037901.1 PFAM: Insertion element protein; KEGG: hdu:HD1971 insertion element IS1 1/2/3/5/6 protein InsA YP_003037902.1 PFAM: IS1 transposase; KEGG: dps:DP0860 insertion element IS1 1/5/6 protein (InsB) YP_003037903.1 PFAM: integrase YP_003037904.1 PFAM: oligogalacturonate-specific porin; KEGG: sfv:SFV_4216 hypothetical protein YP_003037905.1 PFAM: Kelch repeat-containing protein; Kelch repeat protein; KEGG: sfv:SFV_4217 hypothetical protein YP_003037906.1 PFAM: protein of unknown function DUF303 acetylesterase KEGG: sfv:SFV_4218 hypothetical protein YP_003037907.1 KEGG: kpn:KPN_00259 hypothetical protein YP_003037908.1 PFAM: GCN5-related N-acetyltransferase; KEGG: tgr:Tgr7_0152 GCN5-related N-acetyltransferase YP_003037909.1 PFAM: methyltransferase type 11; methyltransferase type 12; KEGG: kpe:KPK_4969 methyltransferase family protein YP_003037910.1 PFAM: peptidase M42 family protein; KEGG: stm:STM1612 cellulase protein YP_003037911.1 PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; KEGG: sea:SeAg_B1548 PTS system, lactose/cellobiose specific IIB subunit YP_003037912.1 TIGRFAM: PTS system, galactitol-specific IIC subunit; PFAM: PTS system Galactitol-specific IIC component; KEGG: sea:SeAg_B1547 PTS system, IIc component YP_003037913.1 PFAM: photosystem I assembly BtpA; KEGG: stm:STM1615 nucleoside triphosphatase YP_003037914.1 PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: sea:SeAg_B1545 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 YP_003037915.1 PFAM: ribulose-phosphate 3-epimerase; KEGG: sew:SeSA_A1734 protein SgcE YP_003037916.1 PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; KEGG: sea:SeAg_B1543 regulatory protein YP_003037917.1 PFAM: Insertion element protein; KEGG: dps:DP0861 insertion element iso-IS1d protein (InsA) YP_003037918.1 PFAM: IS1 transposase; KEGG: dps:DP0860 insertion element IS1 1/5/6 protein (InsB) YP_003037920.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor regulates the genes for iron dicitrate transport YP_003037921.1 with FecA forms the FecAR signal transduction system; ferric citrate binds FecA and transmits a signal across the outer membrane to FecR. FecR transmits a signal across the cytoplasmic membrane and activates the sigma 70 protein FecI that directs the RNA polymerase to express the fecABCDE operon YP_003037922.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; Secretin/TonB short domain; KEGG: sdy:SDY_4297 citrate-dependent iron transport, outer membrane receptor YP_003037923.1 part of the ABC transporter involved in the uptake of citrate-dependent Fe(3+) YP_003037924.1 part of the FecBCDE citrate-dependent iron (III) transporter YP_003037925.1 ferric citrate binds FecA and is transported across the outer membrane while transmits a signal across the cytoplasmic membrane protein FecR. FecR transmits a signal across the membrane and activates the cytoplasmic FecI that directs the RNA polymerase to express the fecABCDE operon (which encodes the ferric citrate outer membrane receptor and the ferric citrate ABC transporter), as well as fecIR. FecD is one of two (along with FecC) integral membrane protein components of the iron dicitrate ABC transporter. YP_003037926.1 Part of the FecBCDE citrate-dependent iron (III) transporter YP_003037927.1 KEGG: eca:ECA2935 hypothetical protein YP_003037928.1 PFAM: transposase IS3/IS911 family protein; KEGG: sfl:SF1439 IS600 ORF1 YP_003037929.1 PFAM: Integrase catalytic region; KEGG: sfl:SF1901 IS600 ORF2 YP_003037930.1 TIGRFAM: choline/carnitine/betaine transporter; PFAM: BCCT transporter; KEGG: sbc:SbBS512_E0764 transporter BCCT family YP_003037931.1 KEGG: kpn:KPN_pKPN3p05959 hypothetical protein YP_003037932.1 PFAM: transposase IS3/IS911 family protein; KEGG: sbc:SbBS512_E2307 IS911, transposase orfA YP_003037933.1 KEGG: ent:Ent638_1538 lipoprotein YP_003037935.1 PFAM: oxidoreductase domain protein; semialdehyde dehydrogenase NAD - binding; oxidoreductase domain; KEGG: pmu:PM1759 hypothetical protein YP_003037936.1 PFAM: general substrate transporter; major facilitator superfamily MFS_1; KEGG: ses:SARI_01868 sialic acid transporter YP_003037937.1 PFAM: transposase IS4 family protein YP_003037938.1 PFAM: integrase; KEGG: ent:Ent638_0463 phage integrase YP_003037939.1 PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; KEGG: sfv:SFV_4229 oxidoreductase YP_003037940.1 KEGG: elf:LF82_1090 thermosensitive gluconokinase; TIGRFAM: carbohydrate kinase, thermoresistant glucokinase family; PFAM: shikimate kinase YP_003037941.1 NAD-binding YP_003037942.1 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate YP_003037943.1 TIGRFAM: gluconate transporter; PFAM: gluconate transporter; citrate transporter; TRAP C4-dicarboxylate transporter permease DctM subunit; KEGG: ssn:SSON_4450 L-idonate transporter YP_003037944.1 PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI YP_003037945.1 PFAM: protein of unknown function DUF853 NPT hydrolase KEGG: ssn:SSON_4448 hypothetical protein YP_003037946.1 PFAM: permease YjgP/YjgQ family protein; KEGG: elf:LF82_3475 inner membrane protein YjgQ YP_003037947.1 PFAM: permease YjgP/YjgQ family protein; KEGG: sbo:SBO_4179 hypothetical protein YP_003037948.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_003037949.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_003037950.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_003037951.1 PFAM: protein of unknown function DUF898 transmembrane; KEGG: sfx:S4493 hypothetical protein YP_003037952.1 PFAM: GCN5-related N-acetyltransferase YP_003037953.1 PFAM: protein of unknown function DUF1260; KEGG: sfl:SF4234 hypothetical protein YP_003037954.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III. YP_003037955.1 KEGG: sbo:SBO_4194 hypothetical protein YP_003037956.1 PFAM: conserved hypothetical protein; KEGG: sdy:SDY_4270 hypothetical protein YP_003037957.1 PFAM: regulatory protein TetR; KEGG: sbc:SbBS512_E4834 TetR family transcriptional regulator YP_003037958.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: ssn:SSON_4429 oxidoreductase YP_003037959.1 PFAM: endoribonuclease L-PSP; KEGG: ssn:SSON_4428 hypothetical protein YP_003037960.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_003037961.1 involved in the allosteric regulation of aspartate carbamoyltransferase YP_003037962.1 TIGRFAM: endoribonuclease L-PSP; PFAM: endoribonuclease L-PSP; KEGG: sdy:SDY_4262 hypothetical protein YP_003037963.1 P-type ATPase involved in magnesium influx YP_003037964.1 regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon YP_003037965.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_003037966.1 KEGG: sfx:S4513 trehalose-6-phosphate hydrolase; TIGRFAM: alpha,alpha-phosphotrehalase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain YP_003037968.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_003037969.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions YP_003037970.1 PFAM: cytochrome b562; KEGG: sfv:SFV_4255 cytochrome b(562) YP_003037971.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD YP_003037972.1 PFAM: protein of unknown function DUF615; KEGG: ssn:SSON_4415 hypothetical protein YP_003037973.1 TIGRFAM: UDP-N-acetylmuramate; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: elf:LF82_1383 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso- diaminop YP_003037974.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_003037975.1 membrane component of a sugar ABC transporter system YP_003037976.1 PFAM: inner-membrane translocator; KEGG: elf:LF82_3716 inner membrane ABC transporter permease YtfT YP_003037977.1 PFAM: ABC transporter; SMART: ATPase AAA; KEGG: elf:LF82_3715 uncharacterized ABC transporter ATP-binding protein YtfR YP_003037978.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: sbc:SbBS512_E4856 sugar ABC transporter periplasmic sugar-binding protein YP_003037979.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_003037980.1 PFAM: AIG2 family protein; KEGG: sfv:SFV_4266 hypothetical protein YP_003037981.1 PFAM: protein of unknown function DUF490; KEGG: elf:LF82_3712 uncharacterized protein YtfN YP_003037982.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: sbc:SbBS512_E4861 outer membrane protein, OMP85 family YP_003037983.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress YP_003037984.1 PFAM: protein of unknown function DUF21; CBS domain containing protein; transporter-associated region; KEGG: elf:LF82_3710 UPF0053 inner membrane protein YtfL YP_003037985.1 PFAM: protein of unknown function DUF1107; KEGG: efe:EFER_4276 hypothetical protein YP_003037986.1 KEGG: elf:LF82_3708 uncharacterized protein YtfJ YP_003037987.1 catalyzes the formation of AMP from adenosine-3',5'-bisphosphate YP_003037988.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate YP_003037989.1 PFAM: helix-turn-helix HxlR type; KEGG: sfv:SFV_4276 hypothetical protein YP_003037990.1 PFAM: NmrA family protein; 3-beta hydroxysteroid dehydrogenase/isomerase; KEGG: sbo:SBO_4231 oxidoreductase YP_003037991.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: ssn:SSON_4395 transmembrane subunit YP_003037992.1 Involved in anaerobic NO protection and iron metabolism YP_003037993.1 involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine YP_003037994.1 FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides YP_003037995.1 PFAM: Opacity-associated protein A; Opacity-associated protein A domain protein; KEGG: sdy:SDY_4376 hypothetical protein YP_003037996.1 PFAM: regulatory protein TetR; KEGG: sbc:SbBS512_E4747 TetR family transcriptional regulator YP_003037997.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_003037998.1 PFAM: xylose isomerase; KEGG: sbo:SBO_4242 hypothetical protein YP_003037999.1 PFAM: enoyl-CoA hydratase/isomerase; KEGG: sbo:SBO_4243 hypothetical protein YP_003038000.1 PFAM: coenzyme A transferase; KEGG: sbc:SbBS512_E4742 CoA-transferase YP_003038001.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: elf:LF82_p707 oxidoreductase YP_003038002.1 PFAM: major facilitator superfamily MFS_1; KEGG: elf:LF82_p706 hexuronate transporter YP_003038003.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_003038004.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_003038005.1 binds single-stranded DNA at the primosome assembly site YP_003038006.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_003038007.1 PFAM: protein of unknown function DUF1471; KEGG: sfv:SFV_4355 hypothetical protein YP_003038008.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_003038009.1 UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway YP_003038010.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization YP_003038011.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_003038012.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_003038013.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr YP_003038014.1 KEGG: ssn:SSON_4374 L-ascorbate 6-phosphate lactonase YP_003038015.1 negative regulator of ulaG and ulaABCDEF YP_003038016.1 YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo YP_003038017.1 in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility YP_003038018.1 PFAM: protein of unknown function DUF1471; KEGG: sfv:SFV_4344 hypothetical protein YP_003038019.1 catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA YP_003038020.1 PFAM: glutathionylspermidine synthase; KEGG: sfx:S4608 synthetase/amidase YP_003038021.1 PFAM: protein of unknown function DUF1190; KEGG: sfv:SFV_4341 hypothetical protein YP_003038022.1 PFAM: protein of unknown function DUF350 YP_003038023.1 KEGG: sbo:SBO_4272 hypothetical protein YP_003038024.1 PFAM: PspA/IM30 family protein YP_003038026.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA YP_003038027.1 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs YP_003038028.1 negatively regulates the transcription of genes upregulated by nitrosative stress YP_003038029.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_003038030.1 KEGG: sfv:SFV_4334 hypothetical protein YP_003038031.1 with HflK inhibits proteolysis of lambda cII protein by FtsH YP_003038032.1 with HflC inhibits proteolysis of lambda cII protein by FtsH YP_003038033.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein YP_003038034.1 Stimulates the elongation of poly(A) tails YP_003038035.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_003038036.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_003038037.1 KEGG: ssn:SSON_4354 N-acetylmuramoyl-L-alanine amidase II; PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin YP_003038038.1 possibly involved in cell wall synthesis YP_003038039.1 TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: protein of unknown function UPF0031; YjeF-family domain protein; KEGG: ssn:SSON_4351 hypothetical protein YP_003038040.1 TIGRFAM: iron-sulfur cluster binding protein; PFAM: domain of unknown function DUF1730; KEGG: sbc:SbBS512_E4697 iron-sulfur cluster binding protein YP_003038041.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_003038042.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_003038043.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_003038044.1 PFAM: MscS Mechanosensitive ion channel; KEGG: sbo:SBO_4298 predicted mechanosensitive channel YP_003038045.1 PFAM: amino acid permease-associated region; KEGG: elf:LF82_3454 inner membrane transporter YjeM YP_003038046.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_003038047.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_003038048.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_003038049.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_003038050.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane YP_003038051.1 PFAM: beta-lactamase; KEGG: sdy:SDY_4394 beta-lactamase YP_003038052.1 lipocalin; globomycin-sensitive outer membrane lipoprotein YP_003038053.1 member of the SMR family of proton-dependent drug efflux transporters; quaternary ammonium compound efflux pump; confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations YP_003038054.1 PFAM: entericidin EcnAB; KEGG: sfv:SFV_4306 entericidin B membrane lipoprotein YP_003038056.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_003038057.1 KEGG: efe:EFER_4198 lysine aminomutase; TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: radical SAM protein YP_003038058.1 KEGG: sbc:SbBS512_E4674 hypothetical protein YP_003038059.1 KEGG: sdy:SDY_4450 hypothetical protein YP_003038060.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_003038061.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_003038062.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function YP_003038063.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein YP_003038064.1 catalyzes the formation of fumarate from aspartate YP_003038065.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB YP_003038066.1 copper binding protein required for copper tolerance; involved in resistance toward heavy metals YP_003038067.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm YP_003038068.1 PFAM: regulatory protein TetR; KEGG: ssn:SSON_4318 transcriptional regulator YP_003038069.1 regulates the cadBA operon YP_003038070.1 antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein YP_003038071.1 PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein YP_003038072.1 TIGRFAM: amino acid/peptide transporter; PFAM: TGF-beta receptor type I/II extracellular region; major facilitator superfamily MFS_1; KEGG: ssn:SSON_4307 peptide transporter YP_003038073.1 class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_003038074.1 KEGG: elf:LF82_3446 uncharacterized protein YjdO YP_003038075.1 KEGG: ssn:SSON_4305 hypothetical protein YP_003038076.1 KEGG: sdy:SDY_4240 hypothetical protein YP_003038077.1 PFAM: protein of unknown function DUF1271 YP_003038078.1 response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration YP_003038079.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters YP_003038080.1 TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily subunit beta; hydro-lyase, Fe-S type, tartrate/fumarate subfamily, subunit alpha; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; Fe-S type hydro-lyase tartrate/fumarate beta region; KEGG: sdy:SDY_4231 fumarase B YP_003038081.1 KEGG: sbo:SBO_4325 hypothetical protein YP_003038082.1 TIGRFAM: sugar (glycoside-Pentoside-Hexuronide) transporter YP_003038083.1 PFAM: glycoside hydrolase family 4 YP_003038084.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type YP_003038085.1 PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein YP_003038086.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: sfv:SFV_4114 AraC-type regulatory protein YP_003038087.1 PFAM: amino acid permease-associated region; KEGG: ssn:SSON_4290 arginine:agmatin antiporter YP_003038088.1 with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division YP_003038089.1 response regulator in two-component regulatory system with BasS YP_003038090.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sfx:S3619 sensor protein BasS/PmrB YP_003038091.1 TIGRFAM: metabolite/H+ symporter, major facilitator superfamily (MFS); PFAM: general substrate transporter; Osmosensory transporter coiled coil; major facilitator superfamily MFS_1; KEGG: sdy:SDY_4102 proline/glycine betaine transporter YP_003038092.1 KEGG: sfv:SFV_4120 hypothetical protein YP_003038093.1 KEGG: sfv:SFV_4121 hypothetical protein YP_003038094.1 TIGRFAM: alkylphosphonate utilization operon protein PhnA; PFAM: PhnA protein; KEGG: sfv:SFV_4122 hypothetical protein YP_003038095.1 PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; 3-demethylubiquinone-9 3-methyltransferase; KEGG: sfv:SFV_4123 hypothetical protein YP_003038096.1 KEGG: ssn:SSON_4281 phosphonate/organophosphate ester transporter subunit; TIGRFAM: phosphonate ABC transporter ATPase subunit; PFAM: ABC transporter; SMART: ATPase AAA YP_003038097.1 TIGRFAM: phosphonate ABC transporter periplasmic phosphonate binding protein; phosphonate ABC transporter periplasmic phosphonate-binding protein; KEGG: sbo:SBO_4130 periplasmic binding protein component of Pn transporter YP_003038098.1 TIGRFAM: phosphonate ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; KEGG: sdy:SDY_4113 membrane channel protein component of Pn transporter YP_003038099.1 may be involved in phosphonate uptake and biodegradation YP_003038100.1 TIGRFAM: phosphonate C-P lyase system protein PhnG; PFAM: phosphonate metabolism PhnG; KEGG: ssn:SSON_4277 phosphonate metabolism YP_003038101.1 TIGRFAM: phosphonate C-P lyase system protein PhnH; PFAM: phosphonate metabolism; KEGG: sdy:SDY_4116 carbon-phosphorus lyase complex subunit YP_003038102.1 PFAM: phosphonate metabolism; KEGG: ssn:SSON_4275 phosphonate metabolism YP_003038103.1 PFAM: phosphonate metabolism PhnJ; KEGG: sbo:SBO_4124 PhnJ YP_003038104.1 KEGG: ssn:SSON_4273 phosphonates transport ATP-binding protein; TIGRFAM: phosphonate C-P lyase system protein PhnK; PFAM: ABC transporter related; SMART: ATPase AAA YP_003038105.1 KEGG: sdy:SDY_4120 ATP-binding component of phosphonate transport; TIGRFAM: phosphonate C-P lyase system protein PhnL; PFAM: ABC transporter related; SMART: ATPase AAA YP_003038106.1 TIGRFAM: phosphonate metabolism protein PhnM; PFAM: amidohydrolase; amidohydrolase; KEGG: ssn:SSON_4271 phosphonate metabolism YP_003038107.1 TIGRFAM: phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN; SMART: guanylate kinase/L-type calcium channel region; KEGG: ssn:SSON_4270 ribose 1,5-bisphosphokinase YP_003038108.1 PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role YP_003038109.1 required for the use of phosphonates and phosphite as phosphorus sources YP_003038110.1 KEGG: sbo:SBO_4117 hypothetical protein YP_003038111.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity YP_003038112.1 involved in rpiB and als operon repression YP_003038113.1 PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: elf:LF82_0076 D-allose-binding periplasmic protein YP_003038114.1 with AlsBC acts to import allose into the cell; AlsA contain 2 ATP-binding domains YP_003038115.1 PFAM: inner-membrane translocator; KEGG: elf:LF82_0077 D-allose transporter permease AlsC YP_003038116.1 PFAM: ribulose-phosphate 3-epimerase; KEGG: elf:LF82_0078 D-allulose-6-phosphate 3-epimerase YP_003038117.1 PFAM: ROK family protein; KEGG: elf:LF82_0079 D-allose kinase YP_003038118.1 PFAM: beta-lactamase; KEGG: elf:LF82_3435 uncharacterized protein YjcS YP_003038119.1 KEGG: sbo:SBO_4114 formate dehydrogenase H YP_003038120.1 with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride YP_003038121.1 possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride YP_003038122.1 part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family YP_003038123.1 PFAM: molybdopterin oxidoreductase Fe4S4 region; KEGG: efe:EFER_4292 formate dehydrogenase-H, selenopolypeptide subunit YP_003038124.1 TIGRFAM: formate dehydrogenase, subunit alpha; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region YP_003038125.1 PFAM: Sel1 domain protein repeat-containing protein; SMART: Sel1 domain protein repeat-containing protein; KEGG: sfv:SFV_4133 hypothetical protein YP_003038126.1 carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transporter YP_003038127.1 PFAM: hypotheticalprotein; SMART: hypothetical protein; KEGG: sfv:SFV_4135 formate-dependent nitrite reductase complex subunit NrfG YP_003038128.1 TIGRFAM: cytochrome C nitrite reductase, accessory protein NrfF; PFAM: cytochrome C biogenesis protein; KEGG: sbc:SbBS512_E4596 formate-dependent nitrite reductase complex, NrfF subunit YP_003038129.1 with NrfF and NrfG catalyzes the insertion of heme into cytochrome C552 YP_003038130.1 TIGRFAM: cytochrome C nitrite reductase, NrfD subunit; PFAM: polysulphide reductase NrfD; KEGG: ssn:SSON_4254 formate-dependent nitrate reductase complex transmembrane protein YP_003038131.1 TIGRFAM: cytochrome C nitrite reductase, Fe-S protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sfv:SFV_4139 formate-dependent nitrite reductase YP_003038132.1 part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia YP_003038133.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552 YP_003038134.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_003038135.1 PFAM: protein of unknown function DUF485; KEGG: sbc:SbBS512_E4587 hypothetical protein YP_003038136.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake YP_003038137.1 TIGRFAM: Na+/H+ antiporter; PFAM: sodium/hydrogen exchanger; KEGG: sdy:SDY_4502 hypothetical protein YP_003038138.1 PFAM: xanthine/uracil/vitamin C permease; sulfate transporter; KEGG: sdy:SDY_4503 hypothetical protein YP_003038139.1 KEGG: sdy:SDY_4504 redox-sensing activator of SoxS; TIGRFAM: redox-sensitive transcriptional activator SoxR; PFAM: transcription regulator MerR DNA binding; regulatory protein MerR; SMART: regulatory protein MerR YP_003038140.1 regulates genes involved in response to oxidative stress YP_003038141.1 PFAM: EAL domain protein; SMART: EAL domain protein; KEGG: sfv:SFV_4151 hypothetical protein YP_003038142.1 KEGG: sbc:SbBS512_E4574 hypothetical protein YP_003038143.1 binds to single stranded DNA and PriA helcase facilitate replication restart YP_003038144.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate YP_003038145.1 PFAM: protein of unknown function DUF419; KEGG: sdy:SDY_4510 hypothetical protein YP_003038146.1 PFAM: protein of unknown function UPF0047; KEGG: sdy:SDY_4511 hypothetical protein YP_003038147.1 class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity YP_003038148.1 KEGG: sfl:SF4150 hypothetical protein YP_003038149.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_003038150.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_003038151.1 unwinds double stranded DNA YP_003038152.1 PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; KEGG: sdy:SDY_4523 quinone oxidoreductase, NADPH-dependent YP_003038153.1 coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia YP_003038154.1 TIGRFAM: TIM-barrel protein, yjbN family; PFAM: dihydrouridine synthase; KEGG: ssn:SSON_4229 tRNA-dihydrouridine synthase A YP_003038155.1 KEGG: sfv:SFV_4165 hypothetical protein YP_003038156.1 KEGG: sfl:SF4158 hypothetical protein YP_003038157.1 Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB YP_003038158.1 unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential YP_003038159.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: sfv:SFV_4169 DNA-damage-inducible SOS response protein YP_003038160.1 Represses a number of genes involved in the response to DNA damage YP_003038161.1 PFAM: diacylglycerol kinase; KEGG: sdy:SDY_4532 diacylglycerol kinase YP_003038162.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA YP_003038163.1 catalyzes the conversion of 4-hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway YP_003038164.1 catalyzes the formation of 4-hydroxybenzoate from chorismate YP_003038165.1 in E. coli, some yjbl mutations have been reported as suppressors of dnaG mutations YP_003038168.1 PFAM: maltose operon periplasmic YP_003038169.1 porin involved in the transport of maltose and maltodextrins YP_003038170.1 with malEFG is involved in import of maltose/maltodextrin YP_003038172.1 functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis YP_003038173.1 with MalKGE is involved in maltose transport into the cell YP_003038174.1 with MalKFE is involved in the transport of maltose into the cell YP_003038175.1 xylose/proton symporter; member of the major facilitator superfamily (MFS) of transporter YP_003038176.1 PFAM: phosphate-starvation-inducible E; KEGG: sfx:S3556 phosphate-starvation-inducible protein PsiE YP_003038177.1 KEGG: sbo:SBO_4058 hypothetical protein YP_003038178.1 PFAM: protein of unknown function DUF940 membrane lipoprotein KEGG: sbc:SbBS512_E4534 lipoprotein YP_003038179.1 PFAM: protein of unknown function DUF1017; KEGG: sbc:SbBS512_E4533 hypothetical protein YP_003038180.1 KEGG: efe:EFER_4119 lipoprotein YP_003038181.1 KEGG: elf:LF82_3422 uncharacterized protein YjbE YP_003038182.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_003038183.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive YP_003038184.1 KEGG: sdy:SDY_4309 hypothetical protein YP_003038185.1 catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA YP_003038186.1 alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family YP_003038187.1 TIGRFAM: sodium-dependent inorganic phosphate (Pi) transporter; Na/Pi-cotransporter II-related protein; PFAM: Na+/Picotransporter; PhoU family protein; KEGG: ssn:SSON_4191 alpha helix protein YP_003038188.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity YP_003038189.1 regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase YP_003038190.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol YP_003038191.1 TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; KEGG: sdy:SDY_4328 isocitrate lyase YP_003038192.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_003038193.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_003038194.1 PFAM: GCN5-related N-acetyltransferase YP_003038195.1 involved in de novo purine biosynthesis YP_003038196.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_003038197.1 DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein YP_003038198.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: sfx:S3660 sensor protein ZraS YP_003038199.1 KEGG: elf:LF82_3728 zinc resistance-associated protein YP_003038200.1 PFAM: protein of unknown function DUF1481; KEGG: sfx:S3662 hypothetical protein YP_003038201.1 histone-like DNA-binding protein YP_003038202.1 PFAM: protein of unknown function DUF416; KEGG: ssn:SSON_4172 hypothetical protein YP_003038203.1 Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures YP_003038204.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_003038205.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates YP_003038206.1 binds specifically to the major sigma factor sigma 70; active in stationary phase YP_003038207.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_003038208.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate YP_003038209.1 TIGRFAM: thiazole biosynthesis adenylyltransferase ThiF; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: sdy:SDY_3734 thiamin biosynthesis, thiazole moiety YP_003038210.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate YP_003038211.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_003038212.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center YP_003038213.1 KEGG: sbo:SBO_4009 heat shock protein YP_003038214.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_003038215.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; subunit beta is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_003038216.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_003038217.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_003038218.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_003038219.1 binds directly to 23S ribosomal RNA YP_003038220.1 Modulates Rho-dependent transcription termination YP_003038221.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_003038222.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_003038223.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_003038224.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_003038225.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_003038226.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_003038227.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs YP_003038228.1 PFAM: protein of unknown function DUF1422; KEGG: sbc:SbBS512_E4450 inner membrane protein YP_003038229.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis YP_003038230.1 catalyzes the conversion of NADPH to NADH YP_003038231.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA YP_003038232.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_003038233.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_003038234.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_003038235.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis YP_003038236.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_003038237.1 PFAM: sulfatase; KEGG: sbc:SbBS512_E4441 sulfatase YP_003038238.1 PFAM: helix-turn-helix- domain containing protein AraC type; SMART: helix-turn-helix- domain containing protein AraC type; KEGG: sfv:SFV_4023 AraC-type regulatory protein YP_003038239.1 FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog YP_003038240.1 KEGG: ssn:SSON_4125 pyruvate formate lyase II activase; TIGRFAM: glycyl-radical enzyme activating protein family; PFAM: radical SAM protein YP_003038241.1 involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein YP_003038242.1 FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS YP_003038243.1 FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site YP_003038244.1 TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing protein; PEP-utilising protein mobile region; PEP-utilising protein domain protein; phosphoryl transfer system HPr; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: elf:LF82_1767 multiphosphoryl transfer protein 2 YP_003038245.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies YP_003038246.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone YP_003038247.1 PFAM: protein of unknown function DUF1287; KEGG: sbc:SbBS512_E4431 hypothetical protein YP_003038248.1 PFAM: protein of unknown function DUF6 transmembrane; KEGG: elf:LF82_3413 uncharacterized inner membrane transporter yiJE YP_003038249.1 TIGRFAM: catalase/peroxidase HPI; PFAM: Haem peroxidase; KEGG: sfv:SFV_4012 catalase; hydroperoxidase HPI(I) YP_003038250.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor YP_003038251.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_003038252.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine YP_003038253.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis YP_003038254.1 member of the NlpC/P60 superfamily of peptidases YP_003038255.1 KEGG: efe:EFER_3835 conserved hypothetical protein; outer membrane lipoprotein YP_003038256.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_003038257.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_003038258.1 negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins YP_003038259.1 TIGRFAM: cell division protein FtsN; PFAM: sporulation domain protein; KEGG: sfl:SF4011 essential cell division protein YP_003038260.1 heat shock protein involved in degradation of misfolded proteins YP_003038261.1 heat shock protein involved in degradation of misfolded proteins YP_003038262.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate YP_003038263.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_003038264.1 PFAM: protein of unknown function DUF904; KEGG: sfl:SF4006 hypothetical protein YP_003038265.1 TIGRFAM: MIP family channel protein; PFAM: major intrinsic protein; KEGG: ssn:SSON_4096 facilitated diffusion of glycerol YP_003038266.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP YP_003038267.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_003038268.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; oxidoreductase FAD-binding domain protein; KEGG: sdy:SDY_3820 ferredoxin-NADP reductase YP_003038269.1 with UspC and Usp E is involved in resistance to UV radiation YP_003038270.1 PFAM: conserved hypothetical protein; KEGG: sfx:S3747 hypothetical protein YP_003038271.1 PFAM: protein of unknown function DUF805; KEGG: ssn:SSON_4090 hypothetical protein YP_003038272.1 PFAM: protein of unknown function DUF1454; KEGG: sfv:SFV_3574 hypothetical protein YP_003038273.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_003038274.1 KEGG: sfv:SFV_3576 CDP-diacylglycerol pyrophosphatase; TIGRFAM: CDP-diacylglycerol pyrophosphatase; PFAM: CDP-diacylglycerol pyrophosphatase YP_003038275.1 TIGRFAM: sulfate ABC transporter periplasmic sulfate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: sfv:SFV_3577 sulfate transporter subunit YP_003038276.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis YP_003038277.1 member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers YP_003038278.1 repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates YP_003038279.1 response regulator in two-component regulatory system with CpxA; part of the envelope stress response system YP_003038280.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors YP_003038281.1 PFAM: MOSC domain containing protein; 3-alpha domain protein; KEGG: sbo:SBO_3928 hypothetical protein YP_003038282.1 transports degraded pectin products into the bacterial cell YP_003038283.1 SodA; manganese binding; only present under aerobic conditions; destroys free radicals YP_003038284.1 transports L-rhamnose and L-lyxose into the cell YP_003038285.1 activates the expression of rhaRS in response to L-rhamnose YP_003038286.1 activates the expression of the rhaBAD operon and rhaT gene YP_003038287.1 KEGG: sbc:SbBS512_E4383 hypothetical protein YP_003038288.1 catalyzes the ATP-dependent phosphorylation of rhamnulose YP_003038289.1 catalyzes the formation of L-rhamnulose from L-rhamnose YP_003038290.1 TIGRFAM: rhamnulose-1-phosphate aldolase; KEGG: sdy:SDY_3844 rhamnulose-1-phosphate aldolase YP_003038291.1 TIGRFAM: L-rhamnose 1-epimerase; KEGG: sdy:SDY_3845 hypothetical protein YP_003038292.1 KEGG: elf:LF82_p621 glycoporin YP_003038293.1 with FrvBRX is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system involved in the transport and phosphorylation of sugars; possibly responsible for the sugar specificity of the system YP_003038294.1 TIGRFAM: PTS system, fructose subfamily, IIC subunit; PTS system, fructose-specific, IIB subunnit; KEGG: sbo:SBO_3915 PTS transporter components IIBC YP_003038295.1 with FrvABR is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system which may be involved in the transport and phosphorylation of sugars YP_003038296.1 repressor of the frv operon, involved in phosphoenolpyruvate:sugar phosphotransferase system YP_003038298.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_003038299.1 TIGRFAM: formate dehydrogenase, subunit alpha; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; KEGG: ssn:SSON_4063 formate dehydrogenase-O, major subunit YP_003038300.1 TIGRFAM: formate dehydrogenase subunit beta; PFAM: formate dehydrogenase transmembrane domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: sfv:SFV_3602 formate dehydrogenase-O, iron-sulfur subunit YP_003038301.1 cytochrome b556(FDO) component; heme containing YP_003038302.1 required for the formation of active formate dehydrogenase YP_003038303.1 KEGG: efe:EFER_2513 4'-phosphopantetheinyl transferase EntD YP_003038304.1 KEGG: sbc:SbBS512_E4369 hypothetical protein YP_003038305.1 PFAM: CopG domain protein DNA-binding domain protein; KEGG: sfv:SFV_3606 hypothetical protein YP_003038307.1 TIGRFAM: thioesterase domain protein; PFAM: GCN5-related N-acetyltransferase; KEGG: sbo:SBO_3902 acetyltransferase YP_003038308.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); defense mechanism against a harmful effect of D-tyrosine YP_003038309.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease YP_003038310.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase; KEGG: ssn:SSON_4054 phosphatase YP_003038311.1 PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; SMART: regulatory protein DeoR YP_003038312.1 PFAM: PfkB domain protein; KEGG: sfx:S3791 kinase YP_003038313.1 PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: sfv:SFV_3617 dehydrogenase YP_003038314.1 PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: sfx:S3793 aldolase YP_003038315.1 PFAM: N-acylglucosamine 2-epimerase; KEGG: sfx:S3794 hypothetical protein YP_003038316.1 KEGG: sfv:SFV_3620 aldose-1-epimerase YP_003038317.1 KEGG: sfv:SFV_3621 alpha-glucosidase YP_003038318.1 TIGRFAM: sugar (glycoside-Pentoside-Hexuronide) transporter; KEGG: sfv:SFV_3622 permease YP_003038319.1 TIGRFAM: sugar (glycoside-Pentoside-Hexuronide) transporter YP_003038320.1 porin involved in the transport of small molecular weight solutes (up to 600 Daltons) across the cell wall; specific substrate still unknown YP_003038322.1 KEGG: sfx:S3803 hypothetical protein YP_003038323.1 SMART: regulatory protein GntR HTH; KEGG: sfv:SFV_3628 transcriptional regulator YP_003038324.1 TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; KEGG: sdy:SDY_3872 GTP-binding protein YP_003038325.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme YP_003038326.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation YP_003038327.1 response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54 YP_003038328.1 KEGG: ses:SARI_03655 hypothetical protein YP_003038329.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_003038330.1 PFAM: protein of unknown function DUF414; KEGG: sfl:SF3936 hypothetical protein YP_003038331.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_003038332.1 KEGG: sbc:SbBS512_E4338 hypothetical protein YP_003038333.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_003038334.1 PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; KEGG: ssn:SSON_4035 endonuclease YP_003038335.1 PFAM: protein of unknown function DUF945; KEGG: sfx:S3815 hypothetical protein YP_003038336.1 KEGG: sbc:SbBS512_E4333 hypothetical protein YP_003038337.1 PFAM: transposase IS4 family protein; KEGG: sea:SeAg_B3181 IS10 transposase YP_003038338.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages YP_003038339.1 PFAM: protein of unknown function DUF1040; KEGG: sdy:SDY_3887 hypothetical protein YP_003038340.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis YP_003038341.1 in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway YP_003038342.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX YP_003038343.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: sdy:SDY_3896 potassium transporter YP_003038344.1 PFAM: protein of unknown function UPF0029; Domain of unknown function DUF1949; KEGG: ssn:SSON_4021 hypothetical protein YP_003038345.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters YP_003038346.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_003038347.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_003038348.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin YP_003038349.1 catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol YP_003038350.1 KEGG: sdy:SDY_3903 transcriptional activator RfaH; TIGRFAM: transcriptional activator RfaH; PFAM: NGN domain protein; SMART: NGN domain protein YP_003038351.1 magnesium dependent; not involved in the Sec-independent protein export system YP_003038352.1 with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane YP_003038353.1 mediates the export of protein precursors bearing twin-arginine signal peptides YP_003038354.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_003038355.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions YP_003038356.1 PFAM: sterol-binding domain protein; KEGG: sbc:SbBS512_E4306 hypothetical protein YP_003038357.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone YP_003038358.1 YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner YP_003038359.1 PFAM: regulatory protein IclR; transcriptional regulator IclR; SMART: regulatory protein IclR; KEGG: elf:LF82_p601 transcriptional regulator YP_003038360.1 PFAM: 2-keto-3-deoxy-galactonokinase; KEGG: elf:LF82_p600 hypothetical protein YP_003038361.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism YP_003038362.1 PFAM: conserved hypothetical protein; KEGG: elf:LF82_p598 hypothetical protein YP_003038363.1 KEGG: elf:LF82_p597 hypothetical protein YP_003038364.1 PFAM: protein of unknown function DUF112 transmembrane; KEGG: elf:LF82_p596 hypothetical protein YP_003038365.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway YP_003038366.1 PFAM: dienelactone hydrolase; KEGG: elf:LF82_3701 carboxymethylenebutenolidase YP_003038368.1 PFAM: isochorismatase hydrolase; KEGG: elf:LF82_p595 hypothetical protein, hypothetica l p rotein YP_003038369.1 KEGG: elf:LF82_p594 hypothetical protein YP_003038370.1 PFAM: FdrA family protein; KEGG: elf:LF82_p593 hypothetical protein YP_003038371.1 PFAM: protein of unknown function DUF1116; KEGG: elf:LF82_p592 hypothetical protein YP_003038372.1 catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP YP_003038373.1 KEGG: elf:LF82_p590 hypothetical protein, hypothetical protein YP_003038374.1 PFAM: permease for cytosine/purines uracil thiamine allantoin; KEGG: elf:LF82_p589 permease YP_003038375.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: elf:LF82_p588 hypothetical protein YP_003038376.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_003038377.1 PFAM: LysR substrate-binding; regulatory protein LysR; KEGG: ssn:SSON_4002 regulator for MetE and MetH YP_003038378.1 TIGRFAM: carboxylate/amino acid/amine transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: ssn:SSON_4001 hypothetical protein YP_003038379.1 purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium YP_003038380.1 lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates YP_003038381.1 TIGRFAM: homoserine/threonine efflux pump; PFAM: lysine exporter protein (LYSE/YGGA); KEGG: sbc:SbBS512_E4291 homoserine/homoserine lactone efflux protein YP_003038382.1 TIGRFAM: homoserine/threonine efflux pump; PFAM: lysine exporter protein (LYSE/YGGA); KEGG: sfv:SFV_3675 threonine efflux system YP_003038383.1 functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway YP_003038384.1 catalyzes the hydrolysis of phosphatidylcholine YP_003038385.1 PFAM: thioesterase superfamily protein; KEGG: sbc:SbBS512_E4287 thioesterase family protein YP_003038386.1 TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6 transmembrane; KEGG: sfv:SFV_3679 hypothetical protein YP_003038387.1 KEGG: sfv:SFV_3681 hypothetical protein YP_003038388.1 KEGG: elf:LF82_p579 hypothetical protein YP_003038389.1 PFAM: protein of unknown function DUF943; KEGG: elf:LF82_p578 hypothetical protein YP_003038390.1 responsible for the influx of magnesium ions YP_003038391.1 KEGG: sbc:SbBS512_E4280 hypothetical protein YP_003038392.1 KEGG: sdy:SDY_3930 predicted periplasmic protein YP_003038393.1 PFAM: protein of unknown function DUF62; KEGG: sdy:SDY_3931 hypothetical protein YP_003038394.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. YP_003038395.1 YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function YP_003038396.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_003038397.1 PFAM: protein of unknown function DUF484; KEGG: sfv:SFV_3689 hypothetical protein YP_003038398.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_003038399.1 KEGG: ssn:SSON_3981 hypothetical protein YP_003038400.1 KEGG: efe:EFER_3695 conserved hypothetical protein; exported protein YP_003038401.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly YP_003038402.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP YP_003038403.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_003038404.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis YP_003038405.1 PFAM: protein of unknown function DUF513 hemX; KEGG: ssn:SSON_3975 uroporphyrinogen III C-methyltransferase YP_003038406.1 TIGRFAM: HemY protein; PFAM: HemY domain protein; hypothetical protein; KEGG: sbc:SbBS512_E4261 HemY protein YP_003038407.1 PFAM: sulfatase; KEGG: elf:LF82_0162 arylsulfatase YP_003038408.1 PFAM: radical SAM protein; KEGG: elf:LF82_0163 arylsulfatase-activating protein AslB YP_003038409.1 uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function YP_003038410.1 KEGG: sfv:SFV_3709 UDP-N-acetyl-D-mannosaminuronic acid transferase; TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family; PFAM: glycosyl transferase WecB/TagA/CpsF YP_003038411.1 enterobacterial common antigen polymerase YP_003038412.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis YP_003038413.1 PFAM: polysaccharide biosynthesis protein; KEGG: sbc:SbBS512_E4129 polysaccharide biosynthesis protein YP_003038414.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis YP_003038415.1 TIGRFAM: TDP-D-fucosamine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; KEGG: elf:LF82_1857 lipopolysaccharide biosynthesis protein RffC YP_003038416.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: nucleotidyl transferase; KEGG: sfv:SFV_3715 glucose-1-phosphate thymidylyltransferase YP_003038417.1 TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; Male sterility domain; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; short-chain dehydrogenase/reductase SDR; dTDP-4-dehydrorhamnose reductase; KEGG: ssn:SSON_3960 dTDP-glucose 4,6-dehydratase YP_003038418.1 catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid YP_003038419.1 KEGG: elf:LF82_1859 UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase YP_003038420.1 Enterobacterial Common antigen (ECA) polysaccharide chain length modulation protein YP_003038421.1 TIGRFAM: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; PFAM: glycosyl transferase family 4; KEGG: sbc:SbBS512_E4137 undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase YP_003038422.1 KEGG: sbo:SBO_3794 hypothetical protein YP_003038423.1 KEGG: sdy:SDY_3966 transcription termination factor Rho; TIGRFAM: transcription termination factor Rho; PFAM: H+transporting two-sector ATPase alpha/subunit beta central region; ribonuclease B OB region domain; Rho termination factor domain protein; Rho termination factor RNA-binding; SMART: Cold shock protein; ATPase AAA YP_003038424.1 KEGG: sfx:S3904 Rho operon leader peptide YP_003038425.1 TIGRFAM: thioredoxin; PFAM: thioredoxin domain; KEGG: sea:SeAg_B4142 thioredoxin YP_003038426.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation YP_003038427.1 catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation YP_003038428.1 single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication YP_003038429.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: sdy:SDY_3973 peptidyl-prolyl cis-trans isomerase C YP_003038430.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_003038431.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate YP_003038432.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway YP_003038433.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_003038434.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_003038435.1 KEGG: sfv:SFV_3733 acetolactate synthase 2 regulatory subunit YP_003038436.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_003038437.1 among the AAA+ ATPases, the YifB protease family belongs to the Helix 2 insert clade; unknown function YP_003038438.1 PFAM: protein of unknown function DUF413; KEGG: sfv:SFV_3736 hypothetical protein YP_003038439.1 negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon YP_003038440.1 PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH YP_003038441.1 TIGRFAM: drug resistance transporter EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1 YP_003038442.1 DNA-binding transcriptional repressor of ribose metabolism YP_003038443.1 catalyzes the formation of D-ribose 5-phosphate from ribose YP_003038444.1 periplasmic substrate-binding component of the ATP-dependent ribose transporter YP_003038445.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B YP_003038446.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain YP_003038447.1 KEGG: sfx:S1483 IS103 orf YP_003038448.1 PFAM: Integrase catalytic region; KEGG: sfv:SFV_3530 IS150 ORF2 YP_003038449.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH YP_003038450.1 interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase YP_003038451.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA YP_003038452.1 catalyzes the formation of asparagine from aspartate and ammonia YP_003038453.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase YP_003038454.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_003038455.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_003038456.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_003038457.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation YP_003038458.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_003038459.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_003038460.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_003038461.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the subunit delta is part of the catalytic core of the ATP synthase complex YP_003038462.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_003038463.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_003038464.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_003038465.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_003038466.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_003038467.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_003038468.1 TIGRFAM: phosphate ABC transporter periplasmic phosphate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: sfx:S4045 phosphate transporter subunit YP_003038469.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_003038470.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_003038471.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_003038472.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon YP_003038473.1 positive regulator of the beta-glucoside operon; transcriptional antiterminator YP_003038474.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_003038475.1 PFAM: glycoside hydrolase family 1; KEGG: efe:EFER_4019 cryptic phospho-beta-glucosidase B YP_003038476.1 PFAM: porin LamB type; KEGG: ssn:SSON_3915 receptor protein YP_003038477.1 PFAM: glycoside hydrolase family 13 domain protein; esterase; KEGG: elf:LF82_3383 uncharacterized protein yiel YP_003038478.1 PFAM: glucosamine/galactosamine-6-phosphate isomerase; KEGG: sfv:SFV_3789 6-phosphogluconolactonase YP_003038479.1 PFAM: protein of unknown function UPF0167; KEGG: efe:EFER_4015 hypothetical protein YP_003038480.1 might be involved in hypersensitivity to nitrofurzone YP_003038481.1 YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily YP_003038482.1 PFAM: xanthine/uracil/vitamin C permease; KEGG: elf:LF82_3380 inner membrane protein YieG YP_003038483.1 PFAM: NADPH-dependent FMN reductase; KEGG: sfv:SFV_3798 hypothetical protein YP_003038484.1 KEGG: sbc:SbBS512_E4210 hypothetical protein YP_003038485.1 Involved in anaerobic NO protection YP_003038486.1 Confers resistance to chloramphenicol YP_003038487.1 tryptophan transporter of low affinity YP_003038488.1 tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan YP_003038489.1 TIGRFAM: tryptophanase leader peptide; PFAM: tryptophanese operon leader peptide; KEGG: efe:EFER_4509 tryptophanase leader peptide YP_003038490.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_003038491.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_003038492.1 PFAM: protein of unknown function DUF37; KEGG: sdy:SDY_4187 hypothetical protein YP_003038493.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_003038494.1 in Escherichia coli transcription of this gene is enhanced by polyamines