-- dump date   	20140619_080846
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
866768000001	DnaA N-terminal domain; Region: DnaA_N; pfam11638
866768000002	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
866768000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866768000004	Walker A motif; other site
866768000005	ATP binding site [chemical binding]; other site
866768000006	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
866768000007	Walker B motif; other site
866768000008	arginine finger; other site
866768000009	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
866768000010	DnaA box-binding interface [nucleotide binding]; other site
866768000011	DNA polymerase III subunit beta; Validated; Region: PRK05643
866768000012	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
866768000013	putative DNA binding surface [nucleotide binding]; other site
866768000014	dimer interface [polypeptide binding]; other site
866768000015	beta-clamp/clamp loader binding surface; other site
866768000016	beta-clamp/translesion DNA polymerase binding surface; other site
866768000017	recF protein; Region: recf; TIGR00611
866768000018	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866768000019	Walker A/P-loop; other site
866768000020	ATP binding site [chemical binding]; other site
866768000021	Q-loop/lid; other site
866768000022	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866768000023	ABC transporter signature motif; other site
866768000024	Walker B; other site
866768000025	D-loop; other site
866768000026	H-loop/switch region; other site
866768000027	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
866768000028	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866768000029	Mg2+ binding site [ion binding]; other site
866768000030	G-X-G motif; other site
866768000031	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
866768000032	anchoring element; other site
866768000033	dimer interface [polypeptide binding]; other site
866768000034	ATP binding site [chemical binding]; other site
866768000035	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
866768000036	active site
866768000037	putative metal-binding site [ion binding]; other site
866768000038	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
866768000039	hypothetical protein; Provisional; Region: PRK11426
866768000040	sugar phosphate phosphatase; Provisional; Region: PRK10513
866768000041	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866768000042	active site
866768000043	motif I; other site
866768000044	motif II; other site
866768000045	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866768000046	hypothetical protein; Provisional; Region: PRK10215
866768000047	Transcriptional regulators [Transcription]; Region: FadR; COG2186
866768000048	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
866768000049	DNA-binding site [nucleotide binding]; DNA binding site
866768000050	FCD domain; Region: FCD; pfam07729
866768000051	2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]; Region: DgoK; COG3734
866768000052	2-keto-3-deoxy-galactonokinase; Region: DGOK; pfam05035
866768000053	2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Reviewed; Region: PRK09140
866768000054	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
866768000055	active site
866768000056	intersubunit interface [polypeptide binding]; other site
866768000057	catalytic residue [active]
866768000058	galactonate dehydratase; Provisional; Region: PRK14017
866768000059	D-galactonate dehydratase catalyses the dehydration of galactonate to 2-keto-3-deoxygalactnate (KDGal), as part of the D-galactonate nonphosphorolytic catabolic Entner-Doudoroff pathway. D-galactonate dehydratase belongs to the enolase superfamily of...; Region: D-galactonate_dehydratase; cd03325
866768000060	putative active site pocket [active]
866768000061	putative metal binding site [ion binding]; other site
866768000062	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768000063	D-galactonate transporter; Region: 2A0114; TIGR00893
866768000064	putative substrate translocation pore; other site
866768000065	putative oxidoreductase; Provisional; Region: PRK11445
866768000066	hypothetical protein; Provisional; Region: PRK07236
866768000067	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
866768000068	hypothetical protein; Provisional; Region: PRK11616
866768000069	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
866768000070	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
866768000071	putative dimer interface [polypeptide binding]; other site
866768000072	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
866768000073	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
866768000074	putative dimer interface [polypeptide binding]; other site
866768000075	putative transporter; Validated; Region: PRK03818
866768000076	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
866768000077	TrkA-C domain; Region: TrkA_C; pfam02080
866768000078	TrkA-C domain; Region: TrkA_C; pfam02080
866768000079	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
866768000080	PTS system, alpha-glucoside-specific IIBC component; Region: PTS-IIBC-alpha; TIGR02005
866768000081	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
866768000082	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
866768000083	active site turn [active]
866768000084	phosphorylation site [posttranslational modification]
866768000085	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
866768000086	Glycoside Hydrolases Family 4; GlvA- and pagL-like glycosidases; Region: GH4_GlvA_pagL_like; cd05298
866768000087	NAD binding site [chemical binding]; other site
866768000088	sugar binding site [chemical binding]; other site
866768000089	divalent metal binding site [ion binding]; other site
866768000090	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
866768000091	dimer interface [polypeptide binding]; other site
866768000092	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
866768000093	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768000094	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
866768000095	putative transporter; Provisional; Region: PRK10484
866768000096	uncharacterized SLC5 subfamily, Escherichia coli YidK-like; solute binding domain; Region: SLC5sbd_YidK; cd10328
866768000097	Na binding site [ion binding]; other site
866768000098	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
866768000099	Sulfatase; Region: Sulfatase; pfam00884
866768000100	Predicted membrane protein [Function unknown]; Region: COG2149
866768000101	Domain of unknown function (DUF202); Region: DUF202; pfam02656
866768000102	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
866768000103	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
866768000104	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768000105	putative substrate translocation pore; other site
866768000106	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
866768000107	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
866768000108	PYR/PP interface [polypeptide binding]; other site
866768000109	dimer interface [polypeptide binding]; other site
866768000110	TPP binding site [chemical binding]; other site
866768000111	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
866768000112	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
866768000113	TPP-binding site [chemical binding]; other site
866768000114	dimer interface [polypeptide binding]; other site
866768000115	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
866768000116	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
866768000117	putative valine binding site [chemical binding]; other site
866768000118	dimer interface [polypeptide binding]; other site
866768000119	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
866768000120	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768000121	active site
866768000122	phosphorylation site [posttranslational modification]
866768000123	intermolecular recognition site; other site
866768000124	dimerization interface [polypeptide binding]; other site
866768000125	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
866768000126	DNA binding residues [nucleotide binding]
866768000127	dimerization interface [polypeptide binding]; other site
866768000128	sensory histidine kinase UhpB; Provisional; Region: PRK11644
866768000129	MASE1; Region: MASE1; pfam05231
866768000130	Histidine kinase; Region: HisKA_3; pfam07730
866768000131	regulatory protein UhpC; Provisional; Region: PRK11663
866768000132	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768000133	putative substrate translocation pore; other site
866768000134	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
866768000135	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768000136	putative substrate translocation pore; other site
866768000137	cryptic adenine deaminase; Provisional; Region: PRK10027
866768000138	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
866768000139	Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295
866768000140	active site
866768000141	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
866768000142	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
866768000143	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
866768000144	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
866768000145	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768000146	putative substrate translocation pore; other site
866768000147	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
866768000148	cytoplasmic membrane lipoprotein-28; Provisional; Region: PRK09861
866768000149	lipoprotein, YaeC family; Region: TIGR00363
866768000150	EamA-like transporter family; Region: EamA; pfam00892
866768000151	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
866768000152	EamA-like transporter family; Region: EamA; pfam00892
866768000153	sugar efflux transporter; Region: 2A0120; TIGR00899
866768000154	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768000155	putative substrate translocation pore; other site
866768000156	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
866768000157	Methyltransferase domain; Region: Methyltransf_27; pfam13708
866768000158	Enterobacterial protein of unknown function (DUF957); Region: DUF957; pfam06117
866768000159	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
866768000160	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
866768000161	Helix-turn-helix domain; Region: HTH_38; pfam13936
866768000162	Integrase core domain; Region: rve; pfam00665
866768000163	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
866768000164	Transposase; Region: HTH_Tnp_1; pfam01527
866768000165	Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951
866768000166	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
866768000167	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
866768000168	Autotransporter beta-domain; Region: Autotransporter; pfam03797
866768000169	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
866768000170	Transposase; Region: HTH_Tnp_1; cl17663
866768000171	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
866768000172	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
866768000173	dimer interface [polypeptide binding]; other site
866768000174	ssDNA binding site [nucleotide binding]; other site
866768000175	tetramer (dimer of dimers) interface [polypeptide binding]; other site
866768000176	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
866768000177	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
866768000178	Glycosyl hydrolase family 31 (GH31) domain of a bacterial protein family represented by Escherichia coli protein Aec37. The gene encoding Aec37 (aec-37) is located within a genomic island (AGI-3) isolated from the extraintestinal avian pathogenic...; Region: GH31_glycosidase_Aec37; cd06599
866768000179	putative active site [active]
866768000180	putative catalytic site [active]
866768000181	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768000182	D-galactonate transporter; Region: 2A0114; TIGR00893
866768000183	putative substrate translocation pore; other site
866768000184	Transcriptional regulators [Transcription]; Region: PurR; COG1609
866768000185	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
866768000186	DNA binding site [nucleotide binding]
866768000187	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
866768000188	ligand binding site [chemical binding]; other site
866768000189	dimerization interface [polypeptide binding]; other site
866768000190	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
866768000191	TPR motif; other site
866768000192	binding surface
866768000193	integrase; Provisional; Region: PRK09692
866768000194	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
866768000195	active site
866768000196	Int/Topo IB signature motif; other site
866768000197	putative transporter; Provisional; Region: PRK11462
866768000198	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
866768000199	putative alpha-glucosidase; Provisional; Region: PRK10658
866768000200	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
866768000201	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
866768000202	active site
866768000203	homotrimer interface [polypeptide binding]; other site
866768000204	catalytic site [active]
866768000205	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
866768000206	AsmA family; Region: AsmA; pfam05170
866768000207	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
866768000208	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
866768000209	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
866768000210	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
866768000211	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
866768000212	generic binding surface II; other site
866768000213	ssDNA binding site; other site
866768000214	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
866768000215	ATP binding site [chemical binding]; other site
866768000216	putative Mg++ binding site [ion binding]; other site
866768000217	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
866768000218	nucleotide binding region [chemical binding]; other site
866768000219	ATP-binding site [chemical binding]; other site
866768000220	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
866768000221	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
866768000222	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
866768000223	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
866768000224	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
866768000225	Zn2+ binding site [ion binding]; other site
866768000226	Mg2+ binding site [ion binding]; other site
866768000227	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
866768000228	synthetase active site [active]
866768000229	NTP binding site [chemical binding]; other site
866768000230	metal binding site [ion binding]; metal-binding site
866768000231	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
866768000232	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
866768000233	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
866768000234	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
866768000235	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
866768000236	catalytic site [active]
866768000237	G-X2-G-X-G-K; other site
866768000238	NAD-dependent DNA ligase LigB; Reviewed; Region: ligB; PRK08097
866768000239	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
866768000240	nucleotide binding pocket [chemical binding]; other site
866768000241	K-X-D-G motif; other site
866768000242	catalytic site [active]
866768000243	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
866768000244	Predicted membrane protein [Function unknown]; Region: COG2860
866768000245	UPF0126 domain; Region: UPF0126; pfam03458
866768000246	UPF0126 domain; Region: UPF0126; pfam03458
866768000247	DNA-damage-inducible protein D; Provisional; Region: dinD; PRK11525
866768000248	BRO family, N-terminal domain; Region: Bro-N; pfam02498
866768000249	hypothetical protein; Provisional; Region: PRK11820
866768000250	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
866768000251	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
866768000252	ribonuclease PH; Reviewed; Region: rph; PRK00173
866768000253	Ribonuclease PH; Region: RNase_PH_bact; cd11362
866768000254	hexamer interface [polypeptide binding]; other site
866768000255	active site
866768000256	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
866768000257	active site
866768000258	division inhibitor protein; Provisional; Region: slmA; PRK09480
866768000259	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
866768000260	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
866768000261	trimer interface [polypeptide binding]; other site
866768000262	active site
866768000263	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
866768000264	Flavoprotein; Region: Flavoprotein; pfam02441
866768000265	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
866768000266	hypothetical protein; Reviewed; Region: PRK00024
866768000267	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
866768000268	MPN+ (JAMM) motif; other site
866768000269	Zinc-binding site [ion binding]; other site
866768000270	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
866768000271	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
866768000272	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
866768000273	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
866768000274	DNA binding site [nucleotide binding]
866768000275	catalytic residue [active]
866768000276	H2TH interface [polypeptide binding]; other site
866768000277	putative catalytic residues [active]
866768000278	turnover-facilitating residue; other site
866768000279	intercalation triad [nucleotide binding]; other site
866768000280	8OG recognition residue [nucleotide binding]; other site
866768000281	putative reading head residues; other site
866768000282	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
866768000283	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
866768000284	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
866768000285	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
866768000286	active site
866768000287	(T/H)XGH motif; other site
866768000288	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
866768000289	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
866768000290	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
866768000291	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10422
866768000292	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
866768000293	putative active site [active]
866768000294	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
866768000295	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
866768000296	lipopolysaccharide core heptose(I) kinase RfaP; Provisional; Region: PRK15123
866768000297	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
866768000298	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
866768000299	Ligand binding site; other site
866768000300	metal-binding site
866768000301	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
866768000302	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
866768000303	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
866768000304	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
866768000305	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
866768000306	Lipopolysaccharide core biosynthesis protein (WaaY); Region: WaaY; pfam06176
866768000307	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
866768000308	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
866768000309	Ligand binding site; other site
866768000310	metal-binding site
866768000311	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
866768000312	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
866768000313	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
866768000314	active site
866768000315	O-Antigen ligase; Region: Wzy_C; pfam04932
866768000316	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
866768000317	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
866768000318	putative active site [active]
866768000319	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
866768000320	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
866768000321	putative active site [active]
866768000322	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
866768000323	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
866768000324	NADP binding site [chemical binding]; other site
866768000325	homopentamer interface [polypeptide binding]; other site
866768000326	substrate binding site [chemical binding]; other site
866768000327	active site
866768000328	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
866768000329	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
866768000330	substrate-cofactor binding pocket; other site
866768000331	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768000332	catalytic residue [active]
866768000333	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
866768000334	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
866768000335	NAD(P) binding site [chemical binding]; other site
866768000336	putative glycosyl transferase; Provisional; Region: PRK10073
866768000337	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
866768000338	active site
866768000339	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
866768000340	NodB motif; other site
866768000341	putative active site [active]
866768000342	putative catalytic site [active]
866768000343	Zn binding site [ion binding]; other site
866768000344	AmiB activator; Provisional; Region: PRK11637
866768000345	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
866768000346	Peptidase family M23; Region: Peptidase_M23; pfam01551
866768000347	phosphoglyceromutase; Provisional; Region: PRK05434
866768000348	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: pgm_bpd_ind; TIGR01307
866768000349	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
866768000350	active site residue [active]
866768000351	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
866768000352	GSH binding site [chemical binding]; other site
866768000353	catalytic residues [active]
866768000354	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
866768000355	SecA binding site; other site
866768000356	Preprotein binding site; other site
866768000357	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
866768000358	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
866768000359	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
866768000360	serine acetyltransferase; Provisional; Region: cysE; PRK11132
866768000361	Serine acetyltransferase, N-terminal; Region: SATase_N; pfam06426
866768000362	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
866768000363	trimer interface [polypeptide binding]; other site
866768000364	active site
866768000365	substrate binding site [chemical binding]; other site
866768000366	CoA binding site [chemical binding]; other site
866768000367	putative rRNA methylase; Provisional; Region: PRK10358
866768000368	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
866768000369	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
866768000370	phosphate binding site [ion binding]; other site
866768000371	DNA-binding transcriptional repressor LldR; Provisional; Region: PRK10421
866768000372	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
866768000373	DNA-binding site [nucleotide binding]; DNA binding site
866768000374	FCD domain; Region: FCD; pfam07729
866768000375	L-lactate permease; Provisional; Region: PRK10420
866768000376	glycolate transporter; Provisional; Region: PRK09695
866768000377	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
866768000378	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
866768000379	trimer interface [polypeptide binding]; other site
866768000380	YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820
866768000381	trimer interface [polypeptide binding]; other site
866768000382	Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295
866768000383	Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507
866768000384	trimer interface [polypeptide binding]; other site
866768000385	Haemagglutinin; Region: HIM; pfam05662
866768000386	Haemagglutinin; Region: HIM; pfam05662
866768000387	YadA-like C-terminal region; Region: YadA; pfam03895
866768000388	Protein of unknown function (DUF3251); Region: DUF3251; cl08186
866768000389	hypothetical protein; Provisional; Region: PRK11020
866768000390	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
866768000391	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
866768000392	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
866768000393	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
866768000394	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
866768000395	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
866768000396	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
866768000397	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
866768000398	active site
866768000399	P-loop; other site
866768000400	phosphorylation site [posttranslational modification]
866768000401	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
866768000402	active site
866768000403	phosphorylation site [posttranslational modification]
866768000404	Protein of unknown function (DUF3302); Region: DUF3302; pfam11742
866768000405	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
866768000406	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
866768000407	HlyD family secretion protein; Region: HlyD_3; pfam13437
866768000408	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
866768000409	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
866768000410	RHS protein; Region: RHS; pfam03527
866768000411	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
866768000412	putative lyase; Provisional; Region: PRK09687
866768000413	PAAR motif; Region: PAAR_motif; cl15808
866768000414	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
866768000415	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
866768000416	putative glutathione S-transferase; Provisional; Region: PRK10357
866768000417	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
866768000418	putative C-terminal domain interface [polypeptide binding]; other site
866768000419	putative GSH binding site (G-site) [chemical binding]; other site
866768000420	putative dimer interface [polypeptide binding]; other site
866768000421	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
866768000422	dimer interface [polypeptide binding]; other site
866768000423	N-terminal domain interface [polypeptide binding]; other site
866768000424	putative substrate binding pocket (H-site) [chemical binding]; other site
866768000425	selenocysteine synthase; Provisional; Region: PRK04311
866768000426	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
866768000427	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
866768000428	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
866768000429	catalytic residue [active]
866768000430	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
866768000431	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
866768000432	G1 box; other site
866768000433	putative GEF interaction site [polypeptide binding]; other site
866768000434	GTP/Mg2+ binding site [chemical binding]; other site
866768000435	Switch I region; other site
866768000436	G2 box; other site
866768000437	G3 box; other site
866768000438	Switch II region; other site
866768000439	G4 box; other site
866768000440	G5 box; other site
866768000441	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
866768000442	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
866768000443	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
866768000444	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
866768000445	putative alcohol dehydrogenase; Provisional; Region: PRK09860
866768000446	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
866768000447	dimer interface [polypeptide binding]; other site
866768000448	active site
866768000449	metal binding site [ion binding]; metal-binding site
866768000450	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like; Region: ALDH_ACDHII-AcoD; cd07116
866768000451	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
866768000452	NAD(P) binding site [chemical binding]; other site
866768000453	catalytic residues [active]
866768000454	Protein of unknown function (DUF3302); Region: DUF3302; pfam11742
866768000455	FlxA-like protein; Region: FlxA; pfam14282
866768000456	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
866768000457	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
866768000458	HlyD family secretion protein; Region: HlyD_3; pfam13437
866768000459	Transcriptional regulator [Transcription]; Region: LysR; COG0583
866768000460	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768000461	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
866768000462	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
866768000463	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
866768000464	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
866768000465	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
866768000466	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
866768000467	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
866768000468	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
866768000469	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768000470	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
866768000471	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
866768000472	intersubunit interface [polypeptide binding]; other site
866768000473	active site
866768000474	Zn2+ binding site [ion binding]; other site
866768000475	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
866768000476	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
866768000477	AP (apurinic/apyrimidinic) site pocket; other site
866768000478	DNA interaction; other site
866768000479	Metal-binding active site; metal-binding site
866768000480	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
866768000481	active site
866768000482	dimer interface [polypeptide binding]; other site
866768000483	magnesium binding site [ion binding]; other site
866768000484	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
866768000485	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
866768000486	putative N- and C-terminal domain interface [polypeptide binding]; other site
866768000487	putative active site [active]
866768000488	MgATP binding site [chemical binding]; other site
866768000489	catalytic site [active]
866768000490	metal binding site [ion binding]; metal-binding site
866768000491	putative xylulose binding site [chemical binding]; other site
866768000492	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
866768000493	tripartite ATP-independent periplasmic transporter solute receptor, DctP family; Region: dctP; TIGR00787
866768000494	L-dehydroascorbate transporter large permease subunit; Provisional; Region: PRK15060
866768000495	DctM-like transporters; Region: DctM; pfam06808
866768000496	2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM; Provisional; Region: PRK09877
866768000497	uncharacterized protein, YhcH/YjgK/YiaL family; Region: TIGR00022
866768000498	2,3-diketo-L-gulonate reductase; Provisional; Region: PRK13260
866768000499	Transcriptional regulator [Transcription]; Region: IclR; COG1414
866768000500	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
866768000501	Bacterial transcriptional regulator; Region: IclR; pfam01614
866768000502	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
866768000503	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
866768000504	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
866768000505	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
866768000506	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768000507	homodimer interface [polypeptide binding]; other site
866768000508	catalytic residue [active]
866768000509	alpha-amylase; Reviewed; Region: malS; PRK09505
866768000510	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
866768000511	active site
866768000512	catalytic site [active]
866768000513	hypothetical protein; Provisional; Region: PRK10356
866768000514	Uncharacterized FlgJ-related protein [General function prediction only]; Region: Bax; COG2992
866768000515	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
866768000516	putative dimerization interface [polypeptide binding]; other site
866768000517	Transcriptional regulators [Transcription]; Region: PurR; COG1609
866768000518	putative ligand binding site [chemical binding]; other site
866768000519	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768000520	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
866768000521	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768000522	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
866768000523	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
866768000524	TM-ABC transporter signature motif; other site
866768000525	D-xylose transporter subunit XylF; Provisional; Region: xylF; PRK10355
866768000526	Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_xylose_binding; cd01538
866768000527	putative ligand binding site [chemical binding]; other site
866768000528	xylose isomerase; Provisional; Region: PRK05474
866768000529	xylose isomerase; Region: xylose_isom_A; TIGR02630
866768000530	xylulokinase; Provisional; Region: PRK15027
866768000531	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
866768000532	N- and C-terminal domain interface [polypeptide binding]; other site
866768000533	active site
866768000534	MgATP binding site [chemical binding]; other site
866768000535	catalytic site [active]
866768000536	metal binding site [ion binding]; metal-binding site
866768000537	xylulose binding site [chemical binding]; other site
866768000538	homodimer interface [polypeptide binding]; other site
866768000539	hypothetical protein; Provisional; Region: PRK11403
866768000540	yiaA/B two helix domain; Region: YiaAB; pfam05360
866768000541	hypothetical protein; Provisional; Region: PRK11383
866768000542	yiaA/B two helix domain; Region: YiaAB; pfam05360
866768000543	yiaA/B two helix domain; Region: YiaAB; pfam05360
866768000544	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
866768000545	Acyltransferase family; Region: Acyl_transf_3; pfam01757
866768000546	Outer membrane lipoprotein Slp family; Region: Slp; cl01164
866768000547	YsaB-like lipoprotein; Region: YsaB; pfam13983
866768000548	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
866768000549	dimer interface [polypeptide binding]; other site
866768000550	motif 1; other site
866768000551	active site
866768000552	motif 2; other site
866768000553	motif 3; other site
866768000554	glycyl-tRNA synthetase, tetrameric type, beta subunit; Region: glyS; TIGR00211
866768000555	DALR anticodon binding domain; Region: DALR_1; pfam05746
866768000556	anticodon binding site; other site
866768000557	tRNA binding surface [nucleotide binding]; other site
866768000558	putative transposase OrfB; Reviewed; Region: PHA02517
866768000559	HTH-like domain; Region: HTH_21; pfam13276
866768000560	Integrase core domain; Region: rve; pfam00665
866768000561	Integrase core domain; Region: rve_2; pfam13333
866768000562	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
866768000563	Helix-turn-helix domain; Region: HTH_28; pfam13518
866768000564	Helix-turn-helix domain; Region: HTH_28; pfam13518
866768000565	small toxic polypeptide; Provisional; Region: PRK09759
866768000566	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
866768000567	DNA-binding site [nucleotide binding]; DNA binding site
866768000568	RNA-binding motif; other site
866768000569	Predicted transcriptional regulator [Transcription]; Region: COG2944
866768000570	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
866768000571	non-specific DNA binding site [nucleotide binding]; other site
866768000572	salt bridge; other site
866768000573	sequence-specific DNA binding site [nucleotide binding]; other site
866768000574	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
866768000575	bifunctional glyoxylate/hydroxypyruvate reductase B; Provisional; Region: PRK15409
866768000576	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
866768000577	dimerization interface [polypeptide binding]; other site
866768000578	ligand binding site [chemical binding]; other site
866768000579	NADP binding site [chemical binding]; other site
866768000580	catalytic site [active]
866768000581	putative outer membrane lipoprotein; Provisional; Region: PRK10510
866768000582	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
866768000583	ligand binding site [chemical binding]; other site
866768000584	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
866768000585	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
866768000586	molybdopterin cofactor binding site [chemical binding]; other site
866768000587	substrate binding site [chemical binding]; other site
866768000588	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
866768000589	molybdopterin cofactor binding site; other site
866768000590	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
866768000591	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
866768000592	Coenzyme A binding pocket [chemical binding]; other site
866768000593	3-methyl-adenine DNA glycosylase I; Provisional; Region: PRK10353
866768000594	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
866768000595	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
866768000596	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768000597	putative substrate translocation pore; other site
866768000598	phosphoethanolamine transferase; Provisional; Region: PRK11560
866768000599	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
866768000600	Sulfatase; Region: Sulfatase; pfam00884
866768000601	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
866768000602	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
866768000603	peptide binding site [polypeptide binding]; other site
866768000604	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
866768000605	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768000606	dimer interface [polypeptide binding]; other site
866768000607	conserved gate region; other site
866768000608	putative PBP binding loops; other site
866768000609	ABC-ATPase subunit interface; other site
866768000610	dipeptide transporter; Provisional; Region: PRK10913
866768000611	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
866768000612	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768000613	dimer interface [polypeptide binding]; other site
866768000614	conserved gate region; other site
866768000615	putative PBP binding loops; other site
866768000616	ABC-ATPase subunit interface; other site
866768000617	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
866768000618	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
866768000619	Walker A/P-loop; other site
866768000620	ATP binding site [chemical binding]; other site
866768000621	Q-loop/lid; other site
866768000622	ABC transporter signature motif; other site
866768000623	Walker B; other site
866768000624	D-loop; other site
866768000625	H-loop/switch region; other site
866768000626	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
866768000627	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
866768000628	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
866768000629	Walker A/P-loop; other site
866768000630	ATP binding site [chemical binding]; other site
866768000631	Q-loop/lid; other site
866768000632	ABC transporter signature motif; other site
866768000633	Walker B; other site
866768000634	D-loop; other site
866768000635	H-loop/switch region; other site
866768000636	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
866768000637	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
866768000638	serine transporter; Region: stp; TIGR00814
866768000639	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
866768000640	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
866768000641	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
866768000642	Protein of unknown function (DUF3260); Region: DUF3260; pfam11658
866768000643	celllulose biosynthesis operon protein BcsF/YhjT; Region: cellullose_BcsF; TIGR03493
866768000644	cellulose biosynthesis protein BcsE; Provisional; Region: PRK15045
866768000645	Protein of unknown function (DUF2819); Region: DUF2819; pfam10995
866768000646	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
866768000647	cell division protein; Provisional; Region: PRK10037
866768000648	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
866768000649	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
866768000650	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
866768000651	DXD motif; other site
866768000652	PilZ domain; Region: PilZ; pfam07238
866768000653	cellulose synthase regulator protein; Provisional; Region: PRK11114
866768000654	endo-1,4-D-glucanase; Provisional; Region: PRK11097
866768000655	cellulose synthase subunit BcsC; Provisional; Region: PRK11447
866768000656	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
866768000657	binding surface
866768000658	TPR motif; other site
866768000659	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
866768000660	binding surface
866768000661	TPR motif; other site
866768000662	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
866768000663	putative diguanylate cyclase; Provisional; Region: PRK13561
866768000664	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
866768000665	metal binding site [ion binding]; metal-binding site
866768000666	active site
866768000667	I-site; other site
866768000668	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
866768000669	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
866768000670	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
866768000671	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
866768000672	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
866768000673	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
866768000674	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
866768000675	substrate binding site [chemical binding]; other site
866768000676	ATP binding site [chemical binding]; other site
866768000677	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
866768000678	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
866768000679	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
866768000680	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768000681	metabolite-proton symporter; Region: 2A0106; TIGR00883
866768000682	putative substrate translocation pore; other site
866768000683	inner membrane protein YhjD; Region: TIGR00766
866768000684	Transcriptional regulator [Transcription]; Region: LysR; COG0583
866768000685	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768000686	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
866768000687	putative effector binding pocket; other site
866768000688	putative dimerization interface [polypeptide binding]; other site
866768000689	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
866768000690	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
866768000691	DNA binding residues [nucleotide binding]
866768000692	dimerization interface [polypeptide binding]; other site
866768000693	trehalase; Provisional; Region: treF; PRK13270
866768000694	Trehalase; Region: Trehalase; pfam01204
866768000695	Haem-binding domain; Region: Haem_bd; pfam14376
866768000696	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
866768000697	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
866768000698	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768000699	catalytic residue [active]
866768000700	DNA-binding transcriptional regulator GadX; Provisional; Region: PRK09978
866768000701	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768000702	transcriptional regulator YdeO; Provisional; Region: PRK09940
866768000703	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768000704	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
866768000705	Protein export membrane protein; Region: SecD_SecF; cl14618
866768000706	multidrug efflux system protein MdtE; Provisional; Region: PRK09859
866768000707	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
866768000708	HlyD family secretion protein; Region: HlyD_3; pfam13437
866768000709	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
866768000710	pyruvate kinase; Provisional; Region: PRK05826
866768000711	acid-resistance membrane protein; Provisional; Region: PRK10209
866768000712	Uncharacterized conserved protein [Function unknown]; Region: HdeD; COG3247
866768000713	acid-resistance protein; Provisional; Region: PRK10208
866768000714	acid-resistance protein; Provisional; Region: hdeB; PRK11566
866768000715	putative Mg(2+) transport ATPase; Provisional; Region: PRK09977
866768000716	MgtC family; Region: MgtC; pfam02308
866768000717	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
866768000718	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
866768000719	DNA binding residues [nucleotide binding]
866768000720	dimerization interface [polypeptide binding]; other site
866768000721	outer membrane lipoprotein, Slp family; Region: slp; TIGR00752
866768000722	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
866768000723	ArsC family; Region: ArsC; pfam03960
866768000724	catalytic residues [active]
866768000725	arsenical pump membrane protein; Provisional; Region: PRK15445
866768000726	Anion permease ArsB.  These permeases have been shown to export arsenate and antimonite in eubacteria and archaea.  A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118
866768000727	transmembrane helices; other site
866768000728	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
866768000729	dimerization interface [polypeptide binding]; other site
866768000730	putative DNA binding site [nucleotide binding]; other site
866768000731	putative Zn2+ binding site [ion binding]; other site
866768000732	glutathione reductase; Validated; Region: PRK06116
866768000733	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
866768000734	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
866768000735	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
866768000736	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
866768000737	oligopeptidase A; Provisional; Region: PRK10911
866768000738	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
866768000739	active site
866768000740	Zn binding site [ion binding]; other site
866768000741	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768000742	S-adenosylmethionine binding site [chemical binding]; other site
866768000743	dipeptide/tripeptide permease B; Provisional; Region: PRK10207
866768000744	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768000745	putative substrate translocation pore; other site
866768000746	POT family; Region: PTR2; pfam00854
866768000747	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
866768000748	Ligand Binding Site [chemical binding]; other site
866768000749	universal stress protein UspB; Provisional; Region: PRK04960
866768000750	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
866768000751	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
866768000752	Predicted flavoproteins [General function prediction only]; Region: COG2081
866768000753	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
866768000754	Protein of unknown function (DUF2776); Region: DUF2776; pfam10951
866768000755	Domain of unknown function (DUF4049); Region: DUF4049; pfam13258
866768000756	Domain of unknown function (DUF4049); Region: DUF4049; pfam13258
866768000757	HlyD family secretion protein; Region: HlyD; pfam00529
866768000758	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
866768000759	HlyD family secretion protein; Region: HlyD_3; pfam13437
866768000760	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
866768000761	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
866768000762	Walker A/P-loop; other site
866768000763	ATP binding site [chemical binding]; other site
866768000764	Q-loop/lid; other site
866768000765	ABC transporter signature motif; other site
866768000766	Walker B; other site
866768000767	D-loop; other site
866768000768	H-loop/switch region; other site
866768000769	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
866768000770	Walker A/P-loop; other site
866768000771	ATP binding site [chemical binding]; other site
866768000772	Q-loop/lid; other site
866768000773	ABC transporter signature motif; other site
866768000774	Walker B; other site
866768000775	D-loop; other site
866768000776	H-loop/switch region; other site
866768000777	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
866768000778	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
866768000779	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
866768000780	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
866768000781	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
866768000782	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
866768000783	Transposase [DNA replication, recombination, and repair]; Region: COG5433
866768000784	Transposase [DNA replication, recombination, and repair]; Region: COG5433
866768000785	putative lyase; Provisional; Region: PRK09687
866768000786	PAAR motif; Region: PAAR_motif; cl15808
866768000787	RHS Repeat; Region: RHS_repeat; pfam05593
866768000788	RHS Repeat; Region: RHS_repeat; pfam05593
866768000789	RHS Repeat; Region: RHS_repeat; pfam05593
866768000790	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
866768000791	RHS Repeat; Region: RHS_repeat; pfam05593
866768000792	RHS Repeat; Region: RHS_repeat; pfam05593
866768000793	RHS protein; Region: RHS; pfam03527
866768000794	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
866768000795	Domain of unknown function (DUF4329); Region: DUF4329; pfam14220
866768000796	nickel responsive regulator; Provisional; Region: PRK02967
866768000797	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
866768000798	nickel transporter ATP-binding protein NikE; Provisional; Region: nikE; PRK10419
866768000799	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
866768000800	Walker A/P-loop; other site
866768000801	ATP binding site [chemical binding]; other site
866768000802	Q-loop/lid; other site
866768000803	ABC transporter signature motif; other site
866768000804	Walker B; other site
866768000805	D-loop; other site
866768000806	H-loop/switch region; other site
866768000807	nickel transporter ATP-binding protein NikD; Provisional; Region: nikD; PRK10418
866768000808	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
866768000809	Walker A/P-loop; other site
866768000810	ATP binding site [chemical binding]; other site
866768000811	Q-loop/lid; other site
866768000812	ABC transporter signature motif; other site
866768000813	Walker B; other site
866768000814	D-loop; other site
866768000815	H-loop/switch region; other site
866768000816	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
866768000817	nickel transporter permease NikC; Provisional; Region: nikC; PRK10417
866768000818	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768000819	dimer interface [polypeptide binding]; other site
866768000820	conserved gate region; other site
866768000821	putative PBP binding loops; other site
866768000822	ABC-ATPase subunit interface; other site
866768000823	nickel transporter permease NikB; Provisional; Region: PRK10352
866768000824	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768000825	dimer interface [polypeptide binding]; other site
866768000826	conserved gate region; other site
866768000827	putative PBP binding loops; other site
866768000828	ABC-ATPase subunit interface; other site
866768000829	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
866768000830	The substrate-binding component of an ABC-type nickel import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA; cd08489
866768000831	substrate binding site [chemical binding]; other site
866768000832	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
866768000833	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
866768000834	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
866768000835	Domain of unknown function DUF20; Region: UPF0118; pfam01594
866768000836	major facilitator superfamily transporter; Provisional; Region: PRK05122
866768000837	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768000838	putative substrate translocation pore; other site
866768000839	hypothetical protein; Provisional; Region: PRK11615
866768000840	hypothetical protein; Provisional; Region: PRK11212
866768000841	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
866768000842	CPxP  motif; other site
866768000843	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
866768000844	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
866768000845	metal-binding site [ion binding]
866768000846	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
866768000847	Predicted membrane protein [Function unknown]; Region: COG3714
866768000848	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
866768000849	hypothetical protein; Provisional; Region: PRK10910
866768000850	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
866768000851	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768000852	S-adenosylmethionine binding site [chemical binding]; other site
866768000853	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
866768000854	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
866768000855	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
866768000856	P loop; other site
866768000857	GTP binding site [chemical binding]; other site
866768000858	cell division protein FtsE; Provisional; Region: PRK10908
866768000859	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866768000860	Walker A/P-loop; other site
866768000861	ATP binding site [chemical binding]; other site
866768000862	Q-loop/lid; other site
866768000863	ABC transporter signature motif; other site
866768000864	Walker B; other site
866768000865	D-loop; other site
866768000866	H-loop/switch region; other site
866768000867	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
866768000868	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
866768000869	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
866768000870	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
866768000871	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
866768000872	DNA binding residues [nucleotide binding]
866768000873	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
866768000874	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
866768000875	dimerization interface [polypeptide binding]; other site
866768000876	ligand binding site [chemical binding]; other site
866768000877	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
866768000878	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
866768000879	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
866768000880	dimerization interface [polypeptide binding]; other site
866768000881	ligand binding site [chemical binding]; other site
866768000882	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
866768000883	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
866768000884	TM-ABC transporter signature motif; other site
866768000885	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
866768000886	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
866768000887	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
866768000888	TM-ABC transporter signature motif; other site
866768000889	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
866768000890	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
866768000891	Walker A/P-loop; other site
866768000892	ATP binding site [chemical binding]; other site
866768000893	Q-loop/lid; other site
866768000894	ABC transporter signature motif; other site
866768000895	Walker B; other site
866768000896	D-loop; other site
866768000897	H-loop/switch region; other site
866768000898	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
866768000899	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
866768000900	Walker A/P-loop; other site
866768000901	ATP binding site [chemical binding]; other site
866768000902	Q-loop/lid; other site
866768000903	ABC transporter signature motif; other site
866768000904	Walker B; other site
866768000905	D-loop; other site
866768000906	H-loop/switch region; other site
866768000907	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
866768000908	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
866768000909	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
866768000910	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768000911	dimer interface [polypeptide binding]; other site
866768000912	conserved gate region; other site
866768000913	putative PBP binding loops; other site
866768000914	ABC-ATPase subunit interface; other site
866768000915	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
866768000916	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768000917	dimer interface [polypeptide binding]; other site
866768000918	conserved gate region; other site
866768000919	putative PBP binding loops; other site
866768000920	ABC-ATPase subunit interface; other site
866768000921	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
866768000922	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
866768000923	Walker A/P-loop; other site
866768000924	ATP binding site [chemical binding]; other site
866768000925	Q-loop/lid; other site
866768000926	ABC transporter signature motif; other site
866768000927	Walker B; other site
866768000928	D-loop; other site
866768000929	H-loop/switch region; other site
866768000930	TOBE domain; Region: TOBE_2; pfam08402
866768000931	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
866768000932	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
866768000933	putative active site [active]
866768000934	catalytic site [active]
866768000935	putative metal binding site [ion binding]; other site
866768000936	hypothetical protein; Provisional; Region: PRK10350
866768000937	gamma-glutamyltranspeptidase; Reviewed; Region: ggt; PRK09615
866768000938	gamma-glutamyltranspeptidase; Region: g_glut_trans; TIGR00066
866768000939	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
866768000940	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
866768000941	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
866768000942	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
866768000943	putative acetyltransferase YhhY; Provisional; Region: PRK10140
866768000944	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
866768000945	Coenzyme A binding pocket [chemical binding]; other site
866768000946	putative oxidoreductase; Provisional; Region: PRK10206
866768000947	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
866768000948	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
866768000949	Pirin-related protein [General function prediction only]; Region: COG1741
866768000950	Pirin; Region: Pirin; pfam02678
866768000951	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
866768000952	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
866768000953	DNA binding site [nucleotide binding]
866768000954	domain linker motif; other site
866768000955	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
866768000956	putative ligand binding site [chemical binding]; other site
866768000957	putative dimerization interface [polypeptide binding]; other site
866768000958	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
866768000959	Shikimate kinase; Region: SKI; pfam01202
866768000960	low affinity gluconate transporter; Provisional; Region: PRK10472
866768000961	gluconate transporter; Region: gntP; TIGR00791
866768000962	putative antibiotic transporter; Provisional; Region: PRK10739
866768000963	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
866768000964	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
866768000965	glycogen branching enzyme; Provisional; Region: PRK05402
866768000966	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
866768000967	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
866768000968	active site
866768000969	catalytic site [active]
866768000970	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
866768000971	glycogen debranching enzyme; Provisional; Region: PRK03705
866768000972	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
866768000973	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
866768000974	active site
866768000975	catalytic site [active]
866768000976	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
866768000977	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
866768000978	ligand binding site; other site
866768000979	oligomer interface; other site
866768000980	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
866768000981	sulfate 1 binding site; other site
866768000982	glycogen synthase; Provisional; Region: glgA; PRK00654
866768000983	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
866768000984	ADP-binding pocket [chemical binding]; other site
866768000985	homodimer interface [polypeptide binding]; other site
866768000986	glycogen phosphorylase; Provisional; Region: PRK14986
866768000987	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
866768000988	homodimer interface [polypeptide binding]; other site
866768000989	active site pocket [active]
866768000990	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
866768000991	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
866768000992	active site residue [active]
866768000993	intramembrane serine protease GlpG; Provisional; Region: PRK10907
866768000994	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
866768000995	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
866768000996	DNA-binding transcriptional repressor GlpR; Provisional; Region: PRK10906
866768000997	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
866768000998	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
866768000999	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: RtcR; COG4650
866768001000	Regulator of RNA terminal phosphate cyclase; Region: RtcR; pfam06956
866768001001	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866768001002	Walker A motif; other site
866768001003	ATP binding site [chemical binding]; other site
866768001004	Walker B motif; other site
866768001005	arginine finger; other site
866768001006	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
866768001007	hypothetical protein; Reviewed; Region: PRK09588
866768001008	RNA 3'-terminal-phosphate cyclase; Provisional; Region: PRK04204
866768001009	RNA 3' phosphate cyclase domain -  RNA phosphate cyclases are enzymes that catalyze the ATP-dependent conversion of 3'-phosphate at the end of RNA into 2', 3'-cyclic phosphodiester bond. The enzymes are conserved in eucaryotes; Region: RNA_Cyclase; cd00295
866768001010	putative active site [active]
866768001011	adenylation catalytic residue [active]
866768001012	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768001013	Major Facilitator Superfamily; Region: MFS_1; pfam07690
866768001014	putative substrate translocation pore; other site
866768001015	tetracycline repressor protein TetR; Provisional; Region: PRK13756
866768001016	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
866768001017	Tetracyclin repressor, C-terminal all-alpha domain; Region: TetR_C; pfam02909
866768001018	maltodextrin phosphorylase; Provisional; Region: PRK14985
866768001019	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
866768001020	homodimer interface [polypeptide binding]; other site
866768001021	active site pocket [active]
866768001022	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
866768001023	4-alpha-glucanotransferase; Region: malQ; TIGR00217
866768001024	high-affinity gluconate transporter; Provisional; Region: PRK14984
866768001025	gluconate transporter; Region: gntP; TIGR00791
866768001026	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
866768001027	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
866768001028	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
866768001029	DNA utilization protein GntX; Provisional; Region: PRK11595
866768001030	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
866768001031	active site
866768001032	carboxylesterase BioH; Provisional; Region: PRK10349
866768001033	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
866768001034	putative transposase; Provisional; Region: PRK09857
866768001035	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
866768001036	ferrous iron transport protein FeoC; Provisional; Region: PRK15431
866768001037	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
866768001038	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
866768001039	G1 box; other site
866768001040	GTP/Mg2+ binding site [chemical binding]; other site
866768001041	Switch I region; other site
866768001042	G2 box; other site
866768001043	G3 box; other site
866768001044	Switch II region; other site
866768001045	G4 box; other site
866768001046	G5 box; other site
866768001047	Nucleoside recognition; Region: Gate; pfam07670
866768001048	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
866768001049	Nucleoside recognition; Region: Gate; pfam07670
866768001050	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
866768001051	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
866768001052	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
866768001053	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
866768001054	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
866768001055	RNA binding site [nucleotide binding]; other site
866768001056	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
866768001057	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
866768001058	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
866768001059	osmolarity response regulator; Provisional; Region: ompR; PRK09468
866768001060	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768001061	active site
866768001062	phosphorylation site [posttranslational modification]
866768001063	intermolecular recognition site; other site
866768001064	dimerization interface [polypeptide binding]; other site
866768001065	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
866768001066	DNA binding site [nucleotide binding]
866768001067	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
866768001068	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
866768001069	dimerization interface [polypeptide binding]; other site
866768001070	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
866768001071	dimer interface [polypeptide binding]; other site
866768001072	phosphorylation site [posttranslational modification]
866768001073	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866768001074	ATP binding site [chemical binding]; other site
866768001075	G-X-G motif; other site
866768001076	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
866768001077	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
866768001078	active site
866768001079	substrate-binding site [chemical binding]; other site
866768001080	metal-binding site [ion binding]
866768001081	ATP binding site [chemical binding]; other site
866768001082	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
866768001083	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
866768001084	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
866768001085	dimerization interface [polypeptide binding]; other site
866768001086	domain crossover interface; other site
866768001087	redox-dependent activation switch; other site
866768001088	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
866768001089	RNA binding surface [nucleotide binding]; other site
866768001090	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
866768001091	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866768001092	motif II; other site
866768001093	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
866768001094	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
866768001095	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
866768001096	ADP-ribose binding site [chemical binding]; other site
866768001097	dimer interface [polypeptide binding]; other site
866768001098	active site
866768001099	nudix motif; other site
866768001100	metal binding site [ion binding]; metal-binding site
866768001101	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
866768001102	Transglycosylase; Region: Transgly; pfam00912
866768001103	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
866768001104	Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972
866768001105	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
866768001106	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
866768001107	Protein of unknown function (DUF2531); Region: DUF2531; pfam10748
866768001108	outer membrane porin HofQ; Provisional; Region: hofQ; PRK10560
866768001109	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
866768001110	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
866768001111	shikimate kinase; Reviewed; Region: aroK; PRK00131
866768001112	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
866768001113	ADP binding site [chemical binding]; other site
866768001114	magnesium binding site [ion binding]; other site
866768001115	putative shikimate binding site; other site
866768001116	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
866768001117	active site
866768001118	dimer interface [polypeptide binding]; other site
866768001119	metal binding site [ion binding]; metal-binding site
866768001120	Uncharacterized protein conserved in bacteria [Function unknown]; Region: DamX; COG3266
866768001121	cell division protein DamX; Validated; Region: PRK10905
866768001122	DNA adenine methylase; Provisional; Region: PRK10904
866768001123	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
866768001124	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
866768001125	substrate binding site [chemical binding]; other site
866768001126	hexamer interface [polypeptide binding]; other site
866768001127	metal binding site [ion binding]; metal-binding site
866768001128	phosphoglycolate phosphatase; Provisional; Region: PRK13222
866768001129	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866768001130	motif II; other site
866768001131	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
866768001132	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
866768001133	active site
866768001134	HIGH motif; other site
866768001135	dimer interface [polypeptide binding]; other site
866768001136	KMSKS motif; other site
866768001137	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
866768001138	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme yhfX; Region: PLPDE_III_yhfX_like; cd06811
866768001139	dimer interface [polypeptide binding]; other site
866768001140	Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457
866768001141	active site
866768001142	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
866768001143	substrate binding site [chemical binding]; other site
866768001144	catalytic residue [active]
866768001145	putative mutase; Provisional; Region: PRK12383
866768001146	Phosphopentomutase [Carbohydrate transport and metabolism]; Region: DeoB; COG1015
866768001147	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
866768001148	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
866768001149	active site
866768001150	substrate binding pocket [chemical binding]; other site
866768001151	homodimer interaction site [polypeptide binding]; other site
866768001152	Protein of unknown function DUF2620; Region: DUF2620; pfam10941
866768001153	Protein of unknown function; Region: YhfT; pfam10797
866768001154	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
866768001155	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
866768001156	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
866768001157	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
866768001158	DNA-binding transcriptional regulator FrlR; Provisional; Region: PRK11402
866768001159	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
866768001160	DNA-binding site [nucleotide binding]; DNA binding site
866768001161	UTRA domain; Region: UTRA; pfam07702
866768001162	Fructoselysine kinase-like.  Fructoselysine is a fructoseamine formed by glycation, a non-enzymatic reaction of glucose with a primary amine followed by an Amadori rearrangement, resulting in a protein that is modified at the amino terminus and at the...; Region: Fructoselysine_kinase_like; cd01940
866768001163	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
866768001164	substrate binding site [chemical binding]; other site
866768001165	ATP binding site [chemical binding]; other site
866768001166	fructoselysine 3-epimerase; Provisional; Region: PRK09856
866768001167	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
866768001168	AP (apurinic/apyrimidinic) site pocket; other site
866768001169	DNA interaction; other site
866768001170	Metal-binding active site; metal-binding site
866768001171	fructoselysine-6-P-deglycase; Provisional; Region: frlB; PRK11382
866768001172	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
866768001173	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
866768001174	dimer interface [polypeptide binding]; other site
866768001175	active site
866768001176	putative fructoselysine transporter; Provisional; Region: frlA; PRK11357
866768001177	hypothetical protein; Provisional; Region: PHA02764
866768001178	Protein of unknown function (DUF4223); Region: DUF4223; pfam13978
866768001179	siroheme synthase; Provisional; Region: cysG; PRK10637
866768001180	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
866768001181	Sirohaem synthase dimerisation region; Region: CysG_dimeriser; pfam10414
866768001182	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
866768001183	active site
866768001184	SAM binding site [chemical binding]; other site
866768001185	homodimer interface [polypeptide binding]; other site
866768001186	nitrite transporter NirC; Provisional; Region: PRK11562
866768001187	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
866768001188	nitrite reductase subunit NirD; Provisional; Region: PRK14989
866768001189	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
866768001190	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
866768001191	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
866768001192	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
866768001193	putative transporter; Provisional; Region: PRK03699
866768001194	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768001195	putative substrate translocation pore; other site
866768001196	peptidyl-prolyl cis-trans isomerase A (rotamase A); Provisional; Region: PRK10903
866768001197	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
866768001198	substrate binding site [chemical binding]; other site
866768001199	hypothetical protein; Provisional; Region: PRK10204
866768001200	Protein involved in cell division [Cell division and chromosome partitioning]; Region: Fic; COG2184
866768001201	cell filamentation protein Fic; Provisional; Region: PRK10347
866768001202	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
866768001203	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
866768001204	glutamine binding [chemical binding]; other site
866768001205	catalytic triad [active]
866768001206	bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein; Reviewed; Region: argD; PRK05093
866768001207	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
866768001208	inhibitor-cofactor binding pocket; inhibition site
866768001209	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768001210	catalytic residue [active]
866768001211	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
866768001212	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
866768001213	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
866768001214	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
866768001215	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
866768001216	ligand binding site [chemical binding]; other site
866768001217	flexible hinge region; other site
866768001218	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
866768001219	putative switch regulator; other site
866768001220	non-specific DNA interactions [nucleotide binding]; other site
866768001221	DNA binding site [nucleotide binding]
866768001222	sequence specific DNA binding site [nucleotide binding]; other site
866768001223	putative cAMP binding site [chemical binding]; other site
866768001224	hypothetical protein; Provisional; Region: PRK10738
866768001225	Phosphoribulokinase-like (PRK-like) is a family of proteins similar to phosphoribulokinase (PRK), the enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. PRK catalyzes the phosphorylation of D-ribulose 5-phosphate to...; Region: PRK_like; cd02029
866768001226	active site
866768001227	hypothetical protein; Provisional; Region: PRK04966
866768001228	putative hydrolase; Provisional; Region: PRK10985
866768001229	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
866768001230	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866768001231	Walker A/P-loop; other site
866768001232	ATP binding site [chemical binding]; other site
866768001233	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
866768001234	ABC transporter signature motif; other site
866768001235	Walker B; other site
866768001236	D-loop; other site
866768001237	ABC transporter; Region: ABC_tran_2; pfam12848
866768001238	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
866768001239	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
866768001240	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
866768001241	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
866768001242	TrkA-N domain; Region: TrkA_N; pfam02254
866768001243	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
866768001244	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
866768001245	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
866768001246	phi X174 lysis protein; Provisional; Region: PRK02793
866768001247	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
866768001248	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
866768001249	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
866768001250	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
866768001251	YheO-like PAS domain; Region: PAS_6; pfam08348
866768001252	HTH domain; Region: HTH_22; pfam13309
866768001253	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
866768001254	sulfur relay protein TusC; Validated; Region: PRK00211
866768001255	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
866768001256	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
866768001257	S17 interaction site [polypeptide binding]; other site
866768001258	S8 interaction site; other site
866768001259	16S rRNA interaction site [nucleotide binding]; other site
866768001260	streptomycin interaction site [chemical binding]; other site
866768001261	23S rRNA interaction site [nucleotide binding]; other site
866768001262	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
866768001263	30S ribosomal protein S7; Validated; Region: PRK05302
866768001264	elongation factor G; Reviewed; Region: PRK00007
866768001265	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
866768001266	G1 box; other site
866768001267	putative GEF interaction site [polypeptide binding]; other site
866768001268	GTP/Mg2+ binding site [chemical binding]; other site
866768001269	Switch I region; other site
866768001270	G2 box; other site
866768001271	G3 box; other site
866768001272	Switch II region; other site
866768001273	G4 box; other site
866768001274	G5 box; other site
866768001275	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
866768001276	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
866768001277	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
866768001278	elongation factor Tu; Reviewed; Region: PRK00049
866768001279	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
866768001280	G1 box; other site
866768001281	GEF interaction site [polypeptide binding]; other site
866768001282	GTP/Mg2+ binding site [chemical binding]; other site
866768001283	Switch I region; other site
866768001284	G2 box; other site
866768001285	G3 box; other site
866768001286	Switch II region; other site
866768001287	G4 box; other site
866768001288	G5 box; other site
866768001289	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
866768001290	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
866768001291	Antibiotic Binding Site [chemical binding]; other site
866768001292	Chitin/cellulose binding domains of chitinase and related enzymes; Region: ChtBD3; cl00046
866768001293	aromatic chitin/cellulose binding site residues [chemical binding]; other site
866768001294	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
866768001295	aromatic chitin/cellulose binding site residues [chemical binding]; other site
866768001296	PF-ChiA is an uncharacterized chitinase found in the hyperthermophilic archaeon Pyrococcus furiosus with a glycosyl hydrolase family 18 (GH18) catalytic domain as well as a cellulose-binding domain.  Members of this domain family are found not only in...; Region: GH18_PF-ChiA-like; cd06543
866768001297	active site
866768001298	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
866768001299	Bacterioferritin (cytochrome b1) [Inorganic ion transport and metabolism]; Region: Bfr; COG2193
866768001300	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
866768001301	heme binding site [chemical binding]; other site
866768001302	ferroxidase pore; other site
866768001303	ferroxidase diiron center [ion binding]; other site
866768001304	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
866768001305	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
866768001306	Type II secretion system (T2SS), protein M; Region: T2SM; pfam04612
866768001307	Type II secretory pathway, component PulL [Intracellular trafficking and secretion]; Region: PulL; COG3297
866768001308	Type II secretion system (T2SS), protein L; Region: T2SL; pfam05134
866768001309	GspL periplasmic domain; Region: GspL_C; pfam12693
866768001310	Type II secretory pathway, component PulK [Intracellular trafficking and secretion]; Region: PulK; COG3156
866768001311	Type II secretory pathway, component PulJ [Intracellular trafficking and secretion]; Region: PulJ; COG4795
866768001312	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
866768001313	Type II secretion system (T2SS), protein J; Region: T2SJ; pfam11612
866768001314	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
866768001315	type II secretion system protein I; Region: gspI; TIGR01707
866768001316	Type II secretion system (T2SS), protein I; Region: T2SI; pfam02501
866768001317	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
866768001318	type II secretion system protein G; Region: typeII_sec_gspG; TIGR01710
866768001319	Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334
866768001320	type II secretion system protein F; Region: GspF; TIGR02120
866768001321	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
866768001322	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
866768001323	Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulE; COG2804
866768001324	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
866768001325	Walker A motif; other site
866768001326	ATP binding site [chemical binding]; other site
866768001327	Walker B motif; other site
866768001328	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
866768001329	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
866768001330	Type II secretory pathway, component PulC [Intracellular trafficking and secretion]; Region: PulC; COG3031
866768001331	Type IV pilus biogenesis; Region: Pilus_PilP; pfam11356
866768001332	AAA domain; Region: AAA_22; pfam13401
866768001333	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
866768001334	protein secretion protein GspB; Provisional; Region: PRK09697
866768001335	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
866768001336	50S ribosomal protein L3, bacterial; Region: L3_bact; TIGR03625
866768001337	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
866768001338	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
866768001339	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
866768001340	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
866768001341	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
866768001342	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
866768001343	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
866768001344	protein-rRNA interface [nucleotide binding]; other site
866768001345	putative translocon binding site; other site
866768001346	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
866768001347	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
866768001348	G-X-X-G motif; other site
866768001349	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
866768001350	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
866768001351	23S rRNA interface [nucleotide binding]; other site
866768001352	5S rRNA interface [nucleotide binding]; other site
866768001353	putative antibiotic binding site [chemical binding]; other site
866768001354	L25 interface [polypeptide binding]; other site
866768001355	L27 interface [polypeptide binding]; other site
866768001356	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
866768001357	23S rRNA interface [nucleotide binding]; other site
866768001358	putative translocon interaction site; other site
866768001359	signal recognition particle (SRP54) interaction site; other site
866768001360	L23 interface [polypeptide binding]; other site
866768001361	trigger factor interaction site; other site
866768001362	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
866768001363	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
866768001364	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
866768001365	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
866768001366	RNA binding site [nucleotide binding]; other site
866768001367	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
866768001368	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
866768001369	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
866768001370	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
866768001371	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
866768001372	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
866768001373	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
866768001374	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
866768001375	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
866768001376	23S rRNA interface [nucleotide binding]; other site
866768001377	5S rRNA interface [nucleotide binding]; other site
866768001378	L27 interface [polypeptide binding]; other site
866768001379	L5 interface [polypeptide binding]; other site
866768001380	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
866768001381	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
866768001382	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
866768001383	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
866768001384	23S rRNA binding site [nucleotide binding]; other site
866768001385	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
866768001386	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
866768001387	SecY translocase; Region: SecY; pfam00344
866768001388	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
866768001389	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
866768001390	30S ribosomal protein S13; Region: bact_S13; TIGR03631
866768001391	30S ribosomal protein S11; Validated; Region: PRK05309
866768001392	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
866768001393	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
866768001394	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
866768001395	RNA binding surface [nucleotide binding]; other site
866768001396	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
866768001397	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
866768001398	alphaNTD homodimer interface [polypeptide binding]; other site
866768001399	alphaNTD - beta interaction site [polypeptide binding]; other site
866768001400	alphaNTD - beta' interaction site [polypeptide binding]; other site
866768001401	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
866768001402	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
866768001403	hypothetical protein; Provisional; Region: PRK10203
866768001404	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
866768001405	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
866768001406	DNA binding residues [nucleotide binding]
866768001407	dimer interface [polypeptide binding]; other site
866768001408	metal binding site [ion binding]; metal-binding site
866768001409	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3036
866768001410	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
866768001411	Large-conductance mechanosensitive channel, MscL; Region: MscL; pfam01741
866768001412	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
866768001413	TrkA-N domain; Region: TrkA_N; pfam02254
866768001414	TrkA-C domain; Region: TrkA_C; pfam02080
866768001415	TrkA-N domain; Region: TrkA_N; pfam02254
866768001416	TrkA-C domain; Region: TrkA_C; pfam02080
866768001417	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
866768001418	putative RNA binding site [nucleotide binding]; other site
866768001419	16S rRNA methyltransferase B; Provisional; Region: PRK10901
866768001420	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768001421	S-adenosylmethionine binding site [chemical binding]; other site
866768001422	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
866768001423	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
866768001424	putative active site [active]
866768001425	substrate binding site [chemical binding]; other site
866768001426	putative cosubstrate binding site; other site
866768001427	catalytic site [active]
866768001428	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
866768001429	substrate binding site [chemical binding]; other site
866768001430	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
866768001431	active site
866768001432	catalytic residues [active]
866768001433	metal binding site [ion binding]; metal-binding site
866768001434	hypothetical protein; Provisional; Region: PRK10736
866768001435	DNA protecting protein DprA; Region: dprA; TIGR00732
866768001436	hypothetical protein; Validated; Region: PRK03430
866768001437	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
866768001438	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
866768001439	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
866768001440	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
866768001441	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
866768001442	shikimate 5-dehydrogenase; Region: aroE; TIGR00507
866768001443	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
866768001444	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
866768001445	shikimate binding site; other site
866768001446	NAD(P) binding site [chemical binding]; other site
866768001447	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
866768001448	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
866768001449	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
866768001450	trimer interface [polypeptide binding]; other site
866768001451	putative metal binding site [ion binding]; other site
866768001452	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
866768001453	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
866768001454	Walker A/P-loop; other site
866768001455	ATP binding site [chemical binding]; other site
866768001456	Q-loop/lid; other site
866768001457	ABC transporter signature motif; other site
866768001458	Walker B; other site
866768001459	D-loop; other site
866768001460	H-loop/switch region; other site
866768001461	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
866768001462	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768001463	dimer interface [polypeptide binding]; other site
866768001464	conserved gate region; other site
866768001465	putative PBP binding loops; other site
866768001466	ABC-ATPase subunit interface; other site
866768001467	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: BatB; COG4597
866768001468	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768001469	conserved gate region; other site
866768001470	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768001471	dimer interface [polypeptide binding]; other site
866768001472	conserved gate region; other site
866768001473	putative PBP binding loops; other site
866768001474	ABC-ATPase subunit interface; other site
866768001475	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
866768001476	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
866768001477	substrate binding pocket [chemical binding]; other site
866768001478	membrane-bound complex binding site; other site
866768001479	hinge residues; other site
866768001480	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
866768001481	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
866768001482	Protein export membrane protein; Region: SecD_SecF; cl14618
866768001483	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
866768001484	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
866768001485	HlyD family secretion protein; Region: HlyD_3; pfam13437
866768001486	DNA-binding transcriptional regulator EnvR; Provisional; Region: PRK09975
866768001487	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
866768001488	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
866768001489	Protein of unknown function (DUF2556); Region: DUF2556; pfam10831
866768001490	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
866768001491	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768001492	DNA methylase; Region: N6_N4_Mtase; pfam01555
866768001493	Factor for inversion stimulation Fis, transcriptional activator [Transcription / DNA replication, recombination, and repair]; Region: Fis; COG2901
866768001494	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
866768001495	tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415
866768001496	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
866768001497	FMN binding site [chemical binding]; other site
866768001498	active site
866768001499	catalytic residues [active]
866768001500	substrate binding site [chemical binding]; other site
866768001501	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
866768001502	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
866768001503	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
866768001504	Na binding site [ion binding]; other site
866768001505	hypothetical protein; Provisional; Region: PRK10633
866768001506	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
866768001507	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
866768001508	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
866768001509	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
866768001510	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
866768001511	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
866768001512	carboxyltransferase (CT) interaction site; other site
866768001513	biotinylation site [posttranslational modification]; other site
866768001514	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
866768001515	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
866768001516	NADP binding site [chemical binding]; other site
866768001517	dimer interface [polypeptide binding]; other site
866768001518	regulatory protein CsrD; Provisional; Region: PRK11059
866768001519	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
866768001520	metal binding site [ion binding]; metal-binding site
866768001521	active site
866768001522	I-site; other site
866768001523	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
866768001524	rod shape-determining protein MreB; Provisional; Region: PRK13927
866768001525	MreB and similar proteins; Region: MreB_like; cd10225
866768001526	nucleotide binding site [chemical binding]; other site
866768001527	Mg binding site [ion binding]; other site
866768001528	putative protofilament interaction site [polypeptide binding]; other site
866768001529	RodZ interaction site [polypeptide binding]; other site
866768001530	rod shape-determining protein MreC; Region: mreC; TIGR00219
866768001531	rod shape-determining protein MreC; Region: MreC; pfam04085
866768001532	rod shape-determining protein MreD; Provisional; Region: PRK11060
866768001533	Maf-like protein; Region: Maf; pfam02545
866768001534	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
866768001535	active site
866768001536	dimer interface [polypeptide binding]; other site
866768001537	ribonuclease G; Provisional; Region: PRK11712
866768001538	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
866768001539	homodimer interface [polypeptide binding]; other site
866768001540	oligonucleotide binding site [chemical binding]; other site
866768001541	hypothetical protein; Provisional; Region: PRK10899
866768001542	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
866768001543	protease TldD; Provisional; Region: tldD; PRK10735
866768001544	transcriptional regulator; Provisional; Region: PRK10632
866768001545	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768001546	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
866768001547	putative effector binding pocket; other site
866768001548	dimerization interface [polypeptide binding]; other site
866768001549	efflux system membrane protein; Provisional; Region: PRK11594
866768001550	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
866768001551	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
866768001552	HlyD family secretion protein; Region: HlyD_3; pfam13437
866768001553	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
866768001554	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
866768001555	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
866768001556	RNAase interaction site [polypeptide binding]; other site
866768001557	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
866768001558	arginine repressor; Provisional; Region: PRK05066
866768001559	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
866768001560	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
866768001561	malate dehydrogenase; Provisional; Region: PRK05086
866768001562	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
866768001563	NAD binding site [chemical binding]; other site
866768001564	dimerization interface [polypeptide binding]; other site
866768001565	Substrate binding site [chemical binding]; other site
866768001566	serine endoprotease; Provisional; Region: PRK10898
866768001567	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
866768001568	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
866768001569	serine endoprotease; Provisional; Region: PRK10139
866768001570	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
866768001571	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
866768001572	protein binding site [polypeptide binding]; other site
866768001573	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
866768001574	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3105
866768001575	hypothetical protein; Provisional; Region: PRK11677
866768001576	Predicted ATPase [General function prediction only]; Region: COG1485
866768001577	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
866768001578	23S rRNA interface [nucleotide binding]; other site
866768001579	L3 interface [polypeptide binding]; other site
866768001580	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
866768001581	stringent starvation protein A; Provisional; Region: sspA; PRK09481
866768001582	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
866768001583	C-terminal domain interface [polypeptide binding]; other site
866768001584	putative GSH binding site (G-site) [chemical binding]; other site
866768001585	dimer interface [polypeptide binding]; other site
866768001586	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
866768001587	dimer interface [polypeptide binding]; other site
866768001588	N-terminal domain interface [polypeptide binding]; other site
866768001589	ClpXP protease specificity-enhancing factor; Provisional; Region: PRK11798
866768001590	putative cryptic C4-dicarboxylate transporter DcuD; Provisional; Region: PRK09804
866768001591	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
866768001592	transcriptional regulator NanR; Provisional; Region: PRK03837
866768001593	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
866768001594	DNA-binding site [nucleotide binding]; DNA binding site
866768001595	FCD domain; Region: FCD; pfam07729
866768001596	N-acetylneuraminate lyase; Region: nanA; TIGR00683
866768001597	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
866768001598	inhibitor site; inhibition site
866768001599	active site
866768001600	dimer interface [polypeptide binding]; other site
866768001601	catalytic residue [active]
866768001602	putative sialic acid transporter; Provisional; Region: PRK03893
866768001603	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768001604	putative substrate translocation pore; other site
866768001605	Putative N-acetylmannosamine-6-phosphate epimerase [Carbohydrate transport and metabolism]; Region: NanE; COG3010
866768001606	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
866768001607	putative active site cavity [active]
866768001608	N-acetylmannosamine kinase; Provisional; Region: PRK05082
866768001609	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
866768001610	nucleotide binding site [chemical binding]; other site
866768001611	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
866768001612	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
866768001613	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
866768001614	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
866768001615	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
866768001616	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
866768001617	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
866768001618	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
866768001619	active site
866768001620	dimer interface [polypeptide binding]; other site
866768001621	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
866768001622	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
866768001623	active site
866768001624	FMN binding site [chemical binding]; other site
866768001625	substrate binding site [chemical binding]; other site
866768001626	3Fe-4S cluster binding site [ion binding]; other site
866768001627	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
866768001628	domain interface; other site
866768001629	radical SAM protein, TIGR01212 family; Region: TIGR01212
866768001630	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866768001631	FeS/SAM binding site; other site
866768001632	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
866768001633	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
866768001634	putative active site [active]
866768001635	heme pocket [chemical binding]; other site
866768001636	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
866768001637	dimer interface [polypeptide binding]; other site
866768001638	phosphorylation site [posttranslational modification]
866768001639	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866768001640	ATP binding site [chemical binding]; other site
866768001641	Mg2+ binding site [ion binding]; other site
866768001642	G-X-G motif; other site
866768001643	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768001644	active site
866768001645	phosphorylation site [posttranslational modification]
866768001646	intermolecular recognition site; other site
866768001647	dimerization interface [polypeptide binding]; other site
866768001648	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
866768001649	putative binding surface; other site
866768001650	active site
866768001651	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
866768001652	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
866768001653	conserved cys residue [active]
866768001654	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
866768001655	Transglycosylase; Region: Transgly; cl17702
866768001656	hypothetical protein; Provisional; Region: PRK10345
866768001657	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
866768001658	dimerization domain swap beta strand [polypeptide binding]; other site
866768001659	regulatory protein interface [polypeptide binding]; other site
866768001660	active site
866768001661	regulatory phosphorylation site [posttranslational modification]; other site
866768001662	P-loop ATPase protein family; Region: ATP_bind_2; pfam03668
866768001663	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
866768001664	active site
866768001665	phosphorylation site [posttranslational modification]
866768001666	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
866768001667	30S subunit binding site; other site
866768001668	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
866768001669	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
866768001670	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
866768001671	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
866768001672	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
866768001673	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
866768001674	Walker A/P-loop; other site
866768001675	ATP binding site [chemical binding]; other site
866768001676	Q-loop/lid; other site
866768001677	ABC transporter signature motif; other site
866768001678	Walker B; other site
866768001679	D-loop; other site
866768001680	H-loop/switch region; other site
866768001681	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
866768001682	lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002
866768001683	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
866768001684	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
866768001685	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
866768001686	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
866768001687	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
866768001688	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
866768001689	putative active site [active]
866768001690	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
866768001691	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
866768001692	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
866768001693	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
866768001694	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
866768001695	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
866768001696	Walker A/P-loop; other site
866768001697	ATP binding site [chemical binding]; other site
866768001698	Q-loop/lid; other site
866768001699	ABC transporter signature motif; other site
866768001700	Walker B; other site
866768001701	D-loop; other site
866768001702	H-loop/switch region; other site
866768001703	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
866768001704	conserved hypothetical integral membrane protein; Region: TIGR00056
866768001705	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
866768001706	mce related protein; Region: MCE; pfam02470
866768001707	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
866768001708	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
866768001709	anti sigma factor interaction site; other site
866768001710	regulatory phosphorylation site [posttranslational modification]; other site
866768001711	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
866768001712	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
866768001713	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
866768001714	hinge; other site
866768001715	active site
866768001716	DNA-binding transcriptional regulator Nlp; Provisional; Region: PRK10344
866768001717	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
866768001718	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
866768001719	substrate binding pocket [chemical binding]; other site
866768001720	chain length determination region; other site
866768001721	substrate-Mg2+ binding site; other site
866768001722	catalytic residues [active]
866768001723	aspartate-rich region 1; other site
866768001724	active site lid residues [active]
866768001725	aspartate-rich region 2; other site
866768001726	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
866768001727	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
866768001728	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
866768001729	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
866768001730	EamA-like transporter family; Region: EamA; pfam00892
866768001731	EamA-like transporter family; Region: EamA; pfam00892
866768001732	GTPase CgtA; Reviewed; Region: obgE; PRK12298
866768001733	GTP1/OBG; Region: GTP1_OBG; pfam01018
866768001734	Obg GTPase; Region: Obg; cd01898
866768001735	G1 box; other site
866768001736	GTP/Mg2+ binding site [chemical binding]; other site
866768001737	Switch I region; other site
866768001738	G2 box; other site
866768001739	G3 box; other site
866768001740	Switch II region; other site
866768001741	G4 box; other site
866768001742	G5 box; other site
866768001743	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
866768001744	D-alanyl-D-alanine carboxypeptidase, serine-type, PBP4 family; Region: PBP4; TIGR00666
866768001745	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
866768001746	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
866768001747	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
866768001748	RNA-binding protein YhbY; Provisional; Region: PRK10343
866768001749	23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293
866768001750	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768001751	S-adenosylmethionine binding site [chemical binding]; other site
866768001752	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
866768001753	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866768001754	Walker A motif; other site
866768001755	ATP binding site [chemical binding]; other site
866768001756	Walker B motif; other site
866768001757	arginine finger; other site
866768001758	Peptidase family M41; Region: Peptidase_M41; pfam01434
866768001759	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
866768001760	dihydropteroate synthase; Region: DHPS; TIGR01496
866768001761	substrate binding pocket [chemical binding]; other site
866768001762	dimer interface [polypeptide binding]; other site
866768001763	inhibitor binding site; inhibition site
866768001764	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
866768001765	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
866768001766	active site
866768001767	substrate binding site [chemical binding]; other site
866768001768	metal binding site [ion binding]; metal-binding site
866768001769	Preprotein translocase SecG subunit; Region: SecG; pfam03840
866768001770	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
866768001771	Sulfatase; Region: Sulfatase; pfam00884
866768001772	argininosuccinate synthase; Validated; Region: PRK05370
866768001773	ribosome maturation protein RimP; Reviewed; Region: PRK00092
866768001774	hypothetical protein; Provisional; Region: PRK14641
866768001775	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
866768001776	putative oligomer interface [polypeptide binding]; other site
866768001777	putative RNA binding site [nucleotide binding]; other site
866768001778	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
866768001779	NusA N-terminal domain; Region: NusA_N; pfam08529
866768001780	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
866768001781	RNA binding site [nucleotide binding]; other site
866768001782	homodimer interface [polypeptide binding]; other site
866768001783	NusA-like KH domain; Region: KH_5; pfam13184
866768001784	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
866768001785	G-X-X-G motif; other site
866768001786	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
866768001787	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
866768001788	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
866768001789	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
866768001790	translation initiation factor IF-2; Region: IF-2; TIGR00487
866768001791	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
866768001792	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
866768001793	G1 box; other site
866768001794	putative GEF interaction site [polypeptide binding]; other site
866768001795	GTP/Mg2+ binding site [chemical binding]; other site
866768001796	Switch I region; other site
866768001797	G2 box; other site
866768001798	G3 box; other site
866768001799	Switch II region; other site
866768001800	G4 box; other site
866768001801	G5 box; other site
866768001802	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
866768001803	Translation-initiation factor 2; Region: IF-2; pfam11987
866768001804	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
866768001805	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
866768001806	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
866768001807	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
866768001808	RNA binding site [nucleotide binding]; other site
866768001809	active site
866768001810	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
866768001811	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
866768001812	16S/18S rRNA binding site [nucleotide binding]; other site
866768001813	S13e-L30e interaction site [polypeptide binding]; other site
866768001814	25S rRNA binding site [nucleotide binding]; other site
866768001815	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
866768001816	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
866768001817	RNase E interface [polypeptide binding]; other site
866768001818	trimer interface [polypeptide binding]; other site
866768001819	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
866768001820	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
866768001821	RNase E interface [polypeptide binding]; other site
866768001822	trimer interface [polypeptide binding]; other site
866768001823	active site
866768001824	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
866768001825	putative nucleic acid binding region [nucleotide binding]; other site
866768001826	G-X-X-G motif; other site
866768001827	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
866768001828	RNA binding site [nucleotide binding]; other site
866768001829	domain interface; other site
866768001830	lipoprotein NlpI; Provisional; Region: PRK11189
866768001831	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
866768001832	binding surface
866768001833	TPR motif; other site
866768001834	ATP-dependent RNA helicase DeaD; Provisional; Region: PRK11634
866768001835	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
866768001836	ATP binding site [chemical binding]; other site
866768001837	Mg++ binding site [ion binding]; other site
866768001838	motif III; other site
866768001839	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
866768001840	nucleotide binding region [chemical binding]; other site
866768001841	ATP-binding site [chemical binding]; other site
866768001842	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
866768001843	putative RNA binding site [nucleotide binding]; other site
866768001844	tryptophan permease; Provisional; Region: PRK10483
866768001845	aromatic amino acid transport protein; Region: araaP; TIGR00837
866768001846	hypothetical protein; Provisional; Region: PRK10508
866768001847	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
866768001848	putative protease; Provisional; Region: PRK15447
866768001849	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
866768001850	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
866768001851	Peptidase family U32; Region: Peptidase_U32; pfam01136
866768001852	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
866768001853	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
866768001854	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
866768001855	Coenzyme A binding pocket [chemical binding]; other site
866768001856	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
866768001857	GIY-YIG motif/motif A; other site
866768001858	putative active site [active]
866768001859	putative metal binding site [ion binding]; other site
866768001860	hypothetical protein; Provisional; Region: PRK03467
866768001861	intracellular protease, PfpI family; Region: PfpI; TIGR01382
866768001862	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
866768001863	proposed catalytic triad [active]
866768001864	conserved cys residue [active]
866768001865	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
866768001866	NADH(P)-binding; Region: NAD_binding_10; pfam13460
866768001867	NAD binding site [chemical binding]; other site
866768001868	active site
866768001869	Predicted permease; Region: DUF318; pfam03773
866768001870	outer membrane lipoprotein; Provisional; Region: PRK11023
866768001871	BON domain; Region: BON; pfam04972
866768001872	BON domain; Region: BON; pfam04972
866768001873	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
866768001874	dimer interface [polypeptide binding]; other site
866768001875	active site
866768001876	TIGR00252 family protein; Region: TIGR00252
866768001877	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
866768001878	Putative lipoprotein [General function prediction only]; Region: LppC; COG3107
866768001879	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
866768001880	putative ligand binding site [chemical binding]; other site
866768001881	SAM-dependent 16S ribosomal RNA C1402 ribose 2'-O-methyltransferase; Provisional; Region: PRK14994
866768001882	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
866768001883	putative SAM binding site [chemical binding]; other site
866768001884	putative homodimer interface [polypeptide binding]; other site
866768001885	Fimbrial protein; Region: Fimbrial; pfam00419
866768001886	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
866768001887	PapC N-terminal domain; Region: PapC_N; pfam13954
866768001888	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
866768001889	PapC C-terminal domain; Region: PapC_C; pfam13953
866768001890	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
866768001891	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
866768001892	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
866768001893	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
866768001894	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
866768001895	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
866768001896	active site
866768001897	trimer interface [polypeptide binding]; other site
866768001898	allosteric site; other site
866768001899	active site lid [active]
866768001900	PTS system N-acetylgalactosamine-specific transporter subunit IID; Provisional; Region: PRK09855
866768001901	PTS system N-acetylgalactosamine-specific transporter subunit IIC; Provisional; Region: PRK09757
866768001902	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
866768001903	active site
866768001904	phosphorylation site [posttranslational modification]
866768001905	Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the...; Region: FTBP_aldolase_II; cd00453
866768001906	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
866768001907	active site
866768001908	intersubunit interface [polypeptide binding]; other site
866768001909	zinc binding site [ion binding]; other site
866768001910	Na+ binding site [ion binding]; other site
866768001911	putative sugar isomerase, AgaS family; Region: agaS_fam; TIGR02815
866768001912	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
866768001913	dimer interface [polypeptide binding]; other site
866768001914	active site
866768001915	AgaS-like protein. AgaS contains a SIS (Sugar ISomerase) domain which is found in many phosphosugar isomerases and phosphosugar binding proteins. AgaS is a putative isomerase in Escherichia coli. It is similar to the glucosamine-6-phosphate synthases; Region: SIS_AgaS_like; cd05010
866768001916	putative active site [active]
866768001917	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
866768001918	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
866768001919	active site
866768001920	dimer interface [polypeptide binding]; other site
866768001921	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
866768001922	active pocket/dimerization site; other site
866768001923	active site
866768001924	phosphorylation site [posttranslational modification]
866768001925	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
866768001926	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
866768001927	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
866768001928	active site
866768001929	phosphorylation site [posttranslational modification]
866768001930	tagatose 6-phosphate aldolase subunit KbaZ; Provisional; Region: PRK15458
866768001931	DNA-binding transcriptional regulator AgaR; Provisional; Region: PRK09802
866768001932	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
866768001933	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
866768001934	putative regulator PrlF; Provisional; Region: PRK09974
866768001935	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
866768001936	galactarate dehydratase; Region: galactar-dH20; TIGR03248
866768001937	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
866768001938	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
866768001939	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768001940	D-galactonate transporter; Region: 2A0114; TIGR00893
866768001941	putative substrate translocation pore; other site
866768001942	alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional; Region: PRK10558
866768001943	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
866768001944	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
866768001945	glycerate kinase I; Provisional; Region: PRK10342
866768001946	hypothetical protein; Provisional; Region: PRK09716
866768001947	DNA-binding transcriptional activator TdcR; Provisional; Region: PRK11424
866768001948	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
866768001949	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768001950	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
866768001951	putative substrate binding pocket [chemical binding]; other site
866768001952	putative dimerization interface [polypeptide binding]; other site
866768001953	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
866768001954	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
866768001955	tetramer interface [polypeptide binding]; other site
866768001956	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768001957	catalytic residue [active]
866768001958	threonine/serine transporter TdcC; Provisional; Region: PRK13629
866768001959	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
866768001960	propionate/acetate kinase; Provisional; Region: PRK12379
866768001961	Acetokinase family; Region: Acetate_kinase; cl17229
866768001962	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
866768001963	Pyruvate formate lyase 1; Region: PFL1; cd01678
866768001964	coenzyme A binding site [chemical binding]; other site
866768001965	active site
866768001966	catalytic residues [active]
866768001967	glycine loop; other site
866768001968	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
866768001969	homotrimer interaction site [polypeptide binding]; other site
866768001970	putative active site [active]
866768001971	L-serine dehydratase TdcG; Provisional; Region: PRK15040
866768001972	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
866768001973	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
866768001974	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
866768001975	serine transporter; Region: stp; TIGR00814
866768001976	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
866768001977	Pirin-related protein [General function prediction only]; Region: COG1741
866768001978	Pirin; Region: Pirin; pfam02678
866768001979	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768001980	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
866768001981	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
866768001982	dimerization interface [polypeptide binding]; other site
866768001983	Predicted membrane protein [Function unknown]; Region: COG3152
866768001984	Predicted membrane protein [Function unknown]; Region: COG3152
866768001985	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
866768001986	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
866768001987	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
866768001988	putative dimer interface [polypeptide binding]; other site
866768001989	N-terminal domain interface [polypeptide binding]; other site
866768001990	putative substrate binding pocket (H-site) [chemical binding]; other site
866768001991	Predicted membrane protein [Function unknown]; Region: COG2259
866768001992	YqjK-like protein; Region: YqjK; pfam13997
866768001993	Predicted membrane protein [Function unknown]; Region: COG5393
866768001994	Uncharacterized conserved protein [Function unknown]; Region: ElaB; COG4575
866768001995	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
866768001996	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
866768001997	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
866768001998	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
866768001999	DNA-binding transcriptional repressor ExuR; Provisional; Region: PRK11523
866768002000	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
866768002001	DNA-binding site [nucleotide binding]; DNA binding site
866768002002	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
866768002003	D-galactonate transporter; Region: 2A0114; TIGR00893
866768002004	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768002005	putative substrate translocation pore; other site
866768002006	Glucuronate isomerase; Region: UxaC; pfam02614
866768002007	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
866768002008	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
866768002009	galactarate dehydratase; Region: galactar-dH20; TIGR03248
866768002010	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
866768002011	Bacterial inner membrane protein; Region: Imp-YgjV; pfam10688
866768002012	serine/threonine transporter SstT; Provisional; Region: PRK13628
866768002013	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
866768002014	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
866768002015	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
866768002016	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
866768002017	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
866768002018	putative active site [active]
866768002019	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
866768002020	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
866768002021	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768002022	S-adenosylmethionine binding site [chemical binding]; other site
866768002023	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4680
866768002024	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
866768002025	non-specific DNA binding site [nucleotide binding]; other site
866768002026	salt bridge; other site
866768002027	sequence-specific DNA binding site [nucleotide binding]; other site
866768002028	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
866768002029	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
866768002030	active site
866768002031	FMN binding site [chemical binding]; other site
866768002032	2,4-decadienoyl-CoA binding site; other site
866768002033	catalytic residue [active]
866768002034	4Fe-4S cluster binding site [ion binding]; other site
866768002035	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
866768002036	alpha-glucosidase; Provisional; Region: PRK10137
866768002037	Protein of unknown function, DUF608; Region: DUF608; pfam04685
866768002038	Trehalase; Region: Trehalase; cl17346
866768002039	inner membrane transporter YjeM; Provisional; Region: PRK15238
866768002040	cryptic beta-D-galactosidase subunit beta; Reviewed; Region: ebgC; PRK10202
866768002041	cryptic beta-D-galactosidase subunit alpha; Reviewed; Region: ebgA; PRK10340
866768002042	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
866768002043	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
866768002044	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
866768002045	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
866768002046	DNA-binding transcriptional repressor EbgR; Provisional; Region: PRK10339
866768002047	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
866768002048	DNA binding site [nucleotide binding]
866768002049	domain linker motif; other site
866768002050	Ligand-binding domain of DNA transcription repressor GalR which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalR; cd01544
866768002051	putative dimerization interface [polypeptide binding]; other site
866768002052	putative ligand binding site [chemical binding]; other site
866768002053	tRNA-binding-domain-containing CsaA-like proteins. CsaA is a molecular chaperone with export related activities. CsaA has a putative tRNA binding activity. The functional unit of CsaA is a homodimer and this domain acts as a dimerization domain; Region: tRNA_bind_CsaA; cd02798
866768002054	dimer interface [polypeptide binding]; other site
866768002055	putative tRNA-binding site [nucleotide binding]; other site
866768002056	putrescine--2-oxoglutarate aminotransferase; Provisional; Region: PRK11522
866768002057	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
866768002058	inhibitor-cofactor binding pocket; inhibition site
866768002059	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768002060	catalytic residue [active]
866768002061	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
866768002062	PAS fold; Region: PAS_3; pfam08447
866768002063	putative active site [active]
866768002064	heme pocket [chemical binding]; other site
866768002065	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
866768002066	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
866768002067	dimer interface [polypeptide binding]; other site
866768002068	putative CheW interface [polypeptide binding]; other site
866768002069	Predicted transcriptional regulators [Transcription]; Region: COG1695
866768002070	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
866768002071	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
866768002072	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
866768002073	FAD binding pocket [chemical binding]; other site
866768002074	FAD binding motif [chemical binding]; other site
866768002075	phosphate binding motif [ion binding]; other site
866768002076	NAD binding pocket [chemical binding]; other site
866768002077	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
866768002078	active site
866768002079	SUMO-1 interface [polypeptide binding]; other site
866768002080	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
866768002081	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
866768002082	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
866768002083	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
866768002084	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
866768002085	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
866768002086	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
866768002087	DNA binding residues [nucleotide binding]
866768002088	DNA primase; Validated; Region: dnaG; PRK05667
866768002089	CHC2 zinc finger; Region: zf-CHC2; pfam01807
866768002090	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
866768002091	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
866768002092	active site
866768002093	metal binding site [ion binding]; metal-binding site
866768002094	interdomain interaction site; other site
866768002095	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
866768002096	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
866768002097	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
866768002098	UGMP family protein; Validated; Region: PRK09604
866768002099	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
866768002100	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
866768002101	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
866768002102	transmembrane helices; other site
866768002103	L(+)-tartrate dehydratase subunit beta; Validated; Region: PRK08228
866768002104	tartrate dehydratase subunit alpha; Validated; Region: PRK08230
866768002105	transcriptional activator TtdR; Provisional; Region: PRK09801
866768002106	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768002107	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
866768002108	putative effector binding pocket; other site
866768002109	putative dimerization interface [polypeptide binding]; other site
866768002110	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
866768002111	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
866768002112	homooctamer interface [polypeptide binding]; other site
866768002113	active site
866768002114	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
866768002115	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
866768002116	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
866768002117	active site
866768002118	NTP binding site [chemical binding]; other site
866768002119	metal binding triad [ion binding]; metal-binding site
866768002120	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
866768002121	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
866768002122	Zn2+ binding site [ion binding]; other site
866768002123	Mg2+ binding site [ion binding]; other site
866768002124	SH3 domain-containing protein; Provisional; Region: PRK10884
866768002125	Bacterial SH3 domain homologues; Region: SH3b; smart00287
866768002126	Uncharacterized conserved protein [Function unknown]; Region: COG3025
866768002127	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
866768002128	putative active site [active]
866768002129	putative metal binding residues [ion binding]; other site
866768002130	signature motif; other site
866768002131	putative triphosphate binding site [ion binding]; other site
866768002132	CHAD domain; Region: CHAD; pfam05235
866768002133	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
866768002134	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
866768002135	metal binding triad; other site
866768002136	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
866768002137	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
866768002138	metal binding triad; other site
866768002139	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
866768002140	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
866768002141	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
866768002142	putative ribose interaction site [chemical binding]; other site
866768002143	putative ADP binding site [chemical binding]; other site
866768002144	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
866768002145	active site
866768002146	nucleotide binding site [chemical binding]; other site
866768002147	HIGH motif; other site
866768002148	KMSKS motif; other site
866768002149	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
866768002150	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
866768002151	Protein of unknown function (DUF1449); Region: DUF1449; pfam07290
866768002152	glycogen synthesis protein GlgS; Provisional; Region: PRK02922
866768002153	Fimbrial protein; Region: Fimbrial; pfam00419
866768002154	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
866768002155	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
866768002156	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
866768002157	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
866768002158	PapC N-terminal domain; Region: PapC_N; pfam13954
866768002159	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
866768002160	PapC C-terminal domain; Region: PapC_C; pfam13953
866768002161	putative fimbrial protein; Provisional; Region: PRK09733
866768002162	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
866768002163	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
866768002164	3,4-dihydroxy-2-butanone 4-phosphate synthase [Coenzyme metabolism]; Region: RibB; COG0108
866768002165	Protein of unknown function (DUF4051); Region: DUF4051; pfam13260
866768002166	zinc transporter ZupT; Provisional; Region: PRK04201
866768002167	ZIP Zinc transporter; Region: Zip; pfam02535
866768002168	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
866768002169	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
866768002170	putative active site [active]
866768002171	metal binding site [ion binding]; metal-binding site
866768002172	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
866768002173	hypothetical protein; Provisional; Region: PRK11653
866768002174	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
866768002175	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
866768002176	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
866768002177	dimer interface [polypeptide binding]; other site
866768002178	ADP-ribose binding site [chemical binding]; other site
866768002179	active site
866768002180	nudix motif; other site
866768002181	metal binding site [ion binding]; metal-binding site
866768002182	putative dehydrogenase; Provisional; Region: PRK11039
866768002183	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
866768002184	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
866768002185	active site
866768002186	metal binding site [ion binding]; metal-binding site
866768002187	hexamer interface [polypeptide binding]; other site
866768002188	esterase YqiA; Provisional; Region: PRK11071
866768002189	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
866768002190	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
866768002191	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866768002192	ATP binding site [chemical binding]; other site
866768002193	Mg2+ binding site [ion binding]; other site
866768002194	G-X-G motif; other site
866768002195	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
866768002196	anchoring element; other site
866768002197	dimer interface [polypeptide binding]; other site
866768002198	ATP binding site [chemical binding]; other site
866768002199	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
866768002200	active site
866768002201	metal binding site [ion binding]; metal-binding site
866768002202	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
866768002203	Uncharacterized conserved protein [Function unknown]; Region: COG1359
866768002204	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
866768002205	sensor protein QseC; Provisional; Region: PRK10337
866768002206	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
866768002207	dimer interface [polypeptide binding]; other site
866768002208	phosphorylation site [posttranslational modification]
866768002209	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866768002210	ATP binding site [chemical binding]; other site
866768002211	Mg2+ binding site [ion binding]; other site
866768002212	G-X-G motif; other site
866768002213	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
866768002214	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768002215	active site
866768002216	phosphorylation site [posttranslational modification]
866768002217	intermolecular recognition site; other site
866768002218	dimerization interface [polypeptide binding]; other site
866768002219	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
866768002220	DNA binding site [nucleotide binding]
866768002221	TIGR00156 family protein; Region: TIGR00156
866768002222	DNA gyrase inhibitor [DNA replication, recombination, and repair]; Region: COG3449
866768002223	Motility quorum-sensing regulator (MqsR); Region: MqsR; cd12869
866768002224	peptide binding site [polypeptide binding]; other site
866768002225	antitoxin MqsA for MqsR toxin; Region: MqsA; cd12870
866768002226	toxin interface [polypeptide binding]; other site
866768002227	putative zinc finger/helix-turn-helix protein, YgiT family; Region: CxxCG_CxxCG_HTH; TIGR03830
866768002228	Zn binding site [ion binding]; other site
866768002229	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
866768002230	non-specific DNA binding site [nucleotide binding]; other site
866768002231	salt bridge; other site
866768002232	sequence-specific DNA binding site [nucleotide binding]; other site
866768002233	putative ABC transporter periplasmic-binding protein; Provisional; Region: PRK09755
866768002234	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
866768002235	peptide binding site [polypeptide binding]; other site
866768002236	DNA topoisomerase IV, A subunit, proteobacterial; Region: parC_Gneg; TIGR01062
866768002237	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
866768002238	CAP-like domain; other site
866768002239	active site
866768002240	primary dimer interface [polypeptide binding]; other site
866768002241	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
866768002242	1-acyl-sn-glycerol-3-phosphate acyltransferase; Provisional; Region: PRK15018
866768002243	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
866768002244	putative acyl-acceptor binding pocket; other site
866768002245	FtsI repressor; Provisional; Region: PRK10883
866768002246	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
866768002247	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
866768002248	hypothetical protein; Provisional; Region: PRK01254
866768002249	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
866768002250	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
866768002251	putative outer membrane lipoprotein; Provisional; Region: PRK09973
866768002252	Protein of unknown function (DUF3828); Region: DUF3828; pfam12883
866768002253	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
866768002254	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
866768002255	active site
866768002256	catalytic tetrad [active]
866768002257	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
866768002258	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
866768002259	dimer interface [polypeptide binding]; other site
866768002260	active site
866768002261	metal binding site [ion binding]; metal-binding site
866768002262	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
866768002263	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
866768002264	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768002265	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768002266	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
866768002267	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
866768002268	cystathionine beta-lyase; Provisional; Region: PRK08114
866768002269	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
866768002270	homodimer interface [polypeptide binding]; other site
866768002271	substrate-cofactor binding pocket; other site
866768002272	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768002273	catalytic residue [active]
866768002274	biopolymer transport protein ExbB; Provisional; Region: PRK10414
866768002275	biopolymer transport protein ExbD; Provisional; Region: PRK11267
866768002276	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
866768002277	oxidoreductase; Provisional; Region: PRK07985
866768002278	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
866768002279	NAD binding site [chemical binding]; other site
866768002280	metal binding site [ion binding]; metal-binding site
866768002281	active site
866768002282	hypothetical protein; Provisional; Region: PRK05208
866768002283	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
866768002284	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
866768002285	active site
866768002286	catalytic tetrad [active]
866768002287	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
866768002288	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
866768002289	Protein of unknown function (DUF2623); Region: DUF2623; pfam11115
866768002290	hydrogenase 2 small subunit; Provisional; Region: PRK10468
866768002291	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
866768002292	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
866768002293	hydrogenase 2 protein HybA; Provisional; Region: PRK10882
866768002294	4Fe-4S binding domain; Region: Fer4_6; pfam12837
866768002295	putative hydrogenase 2 b cytochrome subunit; Provisional; Region: PRK10881
866768002296	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
866768002297	hydrogenase 2 large subunit; Provisional; Region: PRK10467
866768002298	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
866768002299	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
866768002300	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
866768002301	putative substrate-binding site; other site
866768002302	nickel binding site [ion binding]; other site
866768002303	hydrogenase 2-specific chaperone; Provisional; Region: PRK10465
866768002304	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
866768002305	hydrogenase nickel incorporation protein HybF; Provisional; Region: PRK12380
866768002306	hydrogenase 2 accessory protein HypG; Provisional; Region: PRK10413
866768002307	putative S-transferase; Provisional; Region: PRK11752
866768002308	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
866768002309	C-terminal domain interface [polypeptide binding]; other site
866768002310	GSH binding site (G-site) [chemical binding]; other site
866768002311	dimer interface [polypeptide binding]; other site
866768002312	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
866768002313	dimer interface [polypeptide binding]; other site
866768002314	N-terminal domain interface [polypeptide binding]; other site
866768002315	active site
866768002316	bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase; Provisional; Region: PRK10507
866768002317	CHAP domain; Region: CHAP; pfam05257
866768002318	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
866768002319	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
866768002320	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
866768002321	Thymidylate kinase [Nucleotide transport and metabolism]; Region: Tmk; COG0125
866768002322	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
866768002323	TMP-binding site; other site
866768002324	ATP-binding site [chemical binding]; other site
866768002325	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
866768002326	TMP-binding site; other site
866768002327	ATP-binding site [chemical binding]; other site
866768002328	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
866768002329	Thymidylate kinase; Region: Thymidylate_kin; pfam02223
866768002330	active site
866768002331	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
866768002332	Polysaccharide biosynthesis protein; Region: Polysacc_synt_3; pfam13440
866768002333	Transposase domain (DUF772); Region: DUF772; pfam05598
866768002334	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
866768002335	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
866768002336	DNA-binding transcriptional regulator GlcC; Provisional; Region: PRK09990
866768002337	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
866768002338	DNA-binding site [nucleotide binding]; DNA binding site
866768002339	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
866768002340	glycolate oxidase subunit GlcD; Provisional; Region: PRK11230
866768002341	FAD binding domain; Region: FAD_binding_4; pfam01565
866768002342	glycolate oxidase FAD binding subunit; Provisional; Region: glcE; PRK11282
866768002343	FAD binding domain; Region: FAD_binding_4; pfam01565
866768002344	glycolate oxidase iron-sulfur subunit; Provisional; Region: glcF; PRK11274
866768002345	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
866768002346	Cysteine-rich domain; Region: CCG; pfam02754
866768002347	Cysteine-rich domain; Region: CCG; pfam02754
866768002348	hypothetical protein; Provisional; Region: PRK09732
866768002349	Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate...; Region: malate_synt_G; cd00728
866768002350	active site
866768002351	glycolate transporter; Provisional; Region: PRK09695
866768002352	L-lactate permease; Region: Lactate_perm; cl00701
866768002353	Domain of unknown function (DUF4092); Region: DUF4092; pfam13322
866768002354	Peptidase M60-like family; Region: M60-like; pfam13402
866768002355	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
866768002356	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
866768002357	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
866768002358	putative type II secretion protein GspC; Provisional; Region: PRK09681
866768002359	Type IV pilus biogenesis; Region: Pilus_PilP; pfam11356
866768002360	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
866768002361	GspL-like protein; Provisional; Region: PRK09662
866768002362	Type II secretory pathway, component PulL [Intracellular trafficking and secretion]; Region: PulL; COG3297
866768002363	putative general secretion pathway protein YghD; Provisional; Region: PRK09731
866768002364	Uncharacterized membrane protein, possible Na+ channel or pump [General function prediction only]; Region: COG1811
866768002365	ornithine decarboxylase; Provisional; Region: PRK13578
866768002366	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
866768002367	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
866768002368	homodimer interface [polypeptide binding]; other site
866768002369	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768002370	catalytic residue [active]
866768002371	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
866768002372	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
866768002373	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
866768002374	murein transglycosylase C; Provisional; Region: mltC; PRK11671
866768002375	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
866768002376	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
866768002377	N-acetyl-D-glucosamine binding site [chemical binding]; other site
866768002378	catalytic residue [active]
866768002379	oxidative damage protection protein; Provisional; Region: PRK05408
866768002380	adenine DNA glycosylase; Provisional; Region: PRK10880
866768002381	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
866768002382	minor groove reading motif; other site
866768002383	helix-hairpin-helix signature motif; other site
866768002384	substrate binding pocket [chemical binding]; other site
866768002385	active site
866768002386	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576
866768002387	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
866768002388	DNA binding and oxoG recognition site [nucleotide binding]
866768002389	tRNA (guanine-N(7)-)-methyltransferase; Reviewed; Region: trmB; PRK00121
866768002390	hypothetical protein; Provisional; Region: PRK11702
866768002391	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
866768002392	hypothetical protein; Provisional; Region: PRK10626
866768002393	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
866768002394	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cd00411
866768002395	homodimer interface [polypeptide binding]; other site
866768002396	active site
866768002397	Protein of unknown function (DUF1202); Region: DUF1202; pfam06717
866768002398	HemN family oxidoreductase; Provisional; Region: PRK05660
866768002399	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866768002400	FeS/SAM binding site; other site
866768002401	HemN C-terminal domain; Region: HemN_C; pfam06969
866768002402	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
866768002403	active site
866768002404	dimerization interface [polypeptide binding]; other site
866768002405	hypothetical protein; Validated; Region: PRK05090
866768002406	YGGT family; Region: YGGT; pfam02325
866768002407	YGGT family; Region: YGGT; pfam02325
866768002408	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
866768002409	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
866768002410	catalytic residue [active]
866768002411	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
866768002412	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
866768002413	Walker A motif; other site
866768002414	ATP binding site [chemical binding]; other site
866768002415	Walker B motif; other site
866768002416	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
866768002417	hypothetical protein; Validated; Region: PRK00228
866768002418	glutathione synthetase; Provisional; Region: PRK05246
866768002419	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
866768002420	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
866768002421	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
866768002422	RNA methyltransferase, RsmE family; Region: TIGR00046
866768002423	DNA-specific endonuclease I; Provisional; Region: PRK15137
866768002424	Endonuclease I [DNA replication, recombination, and repair]; Region: EndA; COG2356
866768002425	hypothetical protein; Provisional; Region: PRK04860
866768002426	Zn-dependent metalloprotease, SprT family [General function prediction only]; Region: SprT; COG3091
866768002427	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
866768002428	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768002429	putative substrate translocation pore; other site
866768002430	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768002431	S-adenosylmethionine synthetase; Validated; Region: PRK05250
866768002432	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
866768002433	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
866768002434	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
866768002435	Protein of unknown function (DUF2684); Region: DUF2684; pfam10885
866768002436	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
866768002437	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
866768002438	dimer interface [polypeptide binding]; other site
866768002439	active site
866768002440	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
866768002441	catalytic residues [active]
866768002442	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
866768002443	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
866768002444	agmatinase; Region: agmatinase; TIGR01230
866768002445	oligomer interface [polypeptide binding]; other site
866768002446	putative active site [active]
866768002447	Mn binding site [ion binding]; other site
866768002448	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
866768002449	transketolase; Reviewed; Region: PRK12753
866768002450	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
866768002451	TPP-binding site [chemical binding]; other site
866768002452	dimer interface [polypeptide binding]; other site
866768002453	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
866768002454	PYR/PP interface [polypeptide binding]; other site
866768002455	dimer interface [polypeptide binding]; other site
866768002456	TPP binding site [chemical binding]; other site
866768002457	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
866768002458	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
866768002459	active site
866768002460	phosphorylation site [posttranslational modification]
866768002461	Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism]; Region: MtlA; COG2213
866768002462	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
866768002463	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
866768002464	active site
866768002465	P-loop; other site
866768002466	phosphorylation site [posttranslational modification]
866768002467	L-sorbose-1-phosphate reductase; Region: sorbose_phosphate_red; cd08238
866768002468	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
866768002469	putative NAD(P) binding site [chemical binding]; other site
866768002470	catalytic Zn binding site [ion binding]; other site
866768002471	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
866768002472	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
866768002473	putative active site [active]
866768002474	Transcriptional regulator [Transcription]; Region: MtlR; COG3722
866768002475	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10022
866768002476	nucleoside triphosphate hydrolase domain-containing protein; Reviewed; Region: PRK09270
866768002477	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
866768002478	active site
866768002479	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
866768002480	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
866768002481	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
866768002482	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
866768002483	Phosphoglycerate kinase; Region: PGK; pfam00162
866768002484	substrate binding site [chemical binding]; other site
866768002485	hinge regions; other site
866768002486	ADP binding site [chemical binding]; other site
866768002487	catalytic site [active]
866768002488	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
866768002489	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
866768002490	active site
866768002491	intersubunit interface [polypeptide binding]; other site
866768002492	zinc binding site [ion binding]; other site
866768002493	Na+ binding site [ion binding]; other site
866768002494	mechanosensitive channel MscS; Provisional; Region: PRK10334
866768002495	Mechanosensitive ion channel; Region: MS_channel; pfam00924
866768002496	arginine exporter protein; Provisional; Region: PRK09304
866768002497	Uncharacterized conserved protein [Function unknown]; Region: COG2968
866768002498	oxidative stress defense protein; Provisional; Region: PRK11087
866768002499	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768002500	Transcriptional regulator [Transcription]; Region: LysR; COG0583
866768002501	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
866768002502	dimerization interface [polypeptide binding]; other site
866768002503	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
866768002504	succinate CoA transferase; Region: YgfH_subfam; TIGR03458
866768002505	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
866768002506	methylmalonyl-CoA decarboxylase; Provisional; Region: PRK11423
866768002507	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
866768002508	substrate binding site [chemical binding]; other site
866768002509	oxyanion hole (OAH) forming residues; other site
866768002510	trimer interface [polypeptide binding]; other site
866768002511	membrane ATPase/protein kinase; Provisional; Region: PRK09435
866768002512	The function of this protein family is unkown. The protein sequences are similar to the ArgK protein in E. coli. ArgK protein is a membrane ATPase which is required for transporting arginine, ornithine and lysine into the cells by the arginine and...; Region: ArgK-like; cd03114
866768002513	Walker A; other site
866768002514	methylmalonyl-CoA mutase; Reviewed; Region: PRK09426
866768002515	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, Alpha subunit-like subfamily; contains proteins similar to the alpha subunit of Propionbacterium shermanni MCM, as well as human and E. coli MCM. Members of this subfamily contain...; Region: MM_CoA_mutase_alpha_like; cd03679
866768002516	active site
866768002517	substrate binding site [chemical binding]; other site
866768002518	coenzyme B12 binding site [chemical binding]; other site
866768002519	methylmalonyl CoA mutase B12 binding domain. This domain binds to B12 (adenosylcobamide), which initiates the conversion of succinyl CoA and methylmalonyl CoA by forming an adenosyl radical, which then undergoes a rearrangement exchanging a hydrogen atom...; Region: MM_CoA_mut_B12_BD; cd02071
866768002520	B12 binding site [chemical binding]; other site
866768002521	cobalt ligand [ion binding]; other site
866768002522	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
866768002523	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768002524	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
866768002525	putative dimerization interface [polypeptide binding]; other site
866768002526	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
866768002527	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
866768002528	tetramer (dimer of dimers) interface [polypeptide binding]; other site
866768002529	active site
866768002530	dimer interface [polypeptide binding]; other site
866768002531	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
866768002532	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
866768002533	ligand binding site [chemical binding]; other site
866768002534	NAD binding site [chemical binding]; other site
866768002535	tetramer interface [polypeptide binding]; other site
866768002536	catalytic site [active]
866768002537	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
866768002538	L-serine binding site [chemical binding]; other site
866768002539	ACT domain interface; other site
866768002540	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
866768002541	5-formyltetrahydrofolate cyclo-ligase family protein; Provisional; Region: PRK10333
866768002542	Z-ring-associated protein; Provisional; Region: PRK10972
866768002543	hypothetical protein; Reviewed; Region: PRK01736
866768002544	proline aminopeptidase P II; Provisional; Region: PRK10879
866768002545	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
866768002546	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
866768002547	active site
866768002548	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
866768002549	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
866768002550	oxidoreductase; Provisional; Region: PRK08013
866768002551	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
866768002552	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
866768002553	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
866768002554	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
866768002555	lipoyl attachment site [posttranslational modification]; other site
866768002556	glycine dehydrogenase; Provisional; Region: PRK05367
866768002557	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
866768002558	tetramer interface [polypeptide binding]; other site
866768002559	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768002560	catalytic residue [active]
866768002561	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
866768002562	tetramer interface [polypeptide binding]; other site
866768002563	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768002564	catalytic residue [active]
866768002565	putative NAD(P)-binding oxidoreductase; Provisional; Region: PRK09730
866768002566	classical (c) SDRs; Region: SDR_c; cd05233
866768002567	NAD(P) binding site [chemical binding]; other site
866768002568	active site
866768002569	6-phospho-beta-glucosidase BglA; Provisional; Region: PRK15014
866768002570	beta-galactosidase; Region: BGL; TIGR03356
866768002571	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
866768002572	hemolysin; Provisional; Region: PRK15087
866768002573	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
866768002574	putative global regulator; Reviewed; Region: PRK09559
866768002575	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
866768002576	hypothetical protein; Provisional; Region: PRK10878
866768002577	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
866768002578	flavodoxin FldB; Provisional; Region: PRK12359
866768002579	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
866768002580	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
866768002581	active site
866768002582	Int/Topo IB signature motif; other site
866768002583	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
866768002584	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
866768002585	dimerization domain [polypeptide binding]; other site
866768002586	dimer interface [polypeptide binding]; other site
866768002587	catalytic residues [active]
866768002588	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
866768002589	DHH family; Region: DHH; pfam01368
866768002590	DHHA1 domain; Region: DHHA1; pfam02272
866768002591	peptide chain release factor 2; Validated; Region: prfB; PRK00578
866768002592	This domain is found in peptide chain release factors; Region: PCRF; smart00937
866768002593	RF-1 domain; Region: RF-1; pfam00472
866768002594	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
866768002595	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
866768002596	dimer interface [polypeptide binding]; other site
866768002597	putative anticodon binding site; other site
866768002598	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
866768002599	motif 1; other site
866768002600	active site
866768002601	motif 2; other site
866768002602	motif 3; other site
866768002603	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
866768002604	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
866768002605	active site
866768002606	metal binding site [ion binding]; metal-binding site
866768002607	nudix motif; other site
866768002608	xanthine permease; Region: pbuX; TIGR03173
866768002609	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12809
866768002610	4Fe-4S binding domain; Region: Fer4; pfam00037
866768002611	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
866768002612	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
866768002613	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
866768002614	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
866768002615	guanine deaminase; Provisional; Region: PRK09228
866768002616	Guanine deaminase (GDEase). Guanine deaminase is an aminohydrolase responsible for the conversion of guanine to xanthine and ammonia, the first step to utilize guanine as a nitrogen source. This reaction also removes the guanine base from the pool and...; Region: GDEase; cd01303
866768002617	active site
866768002618	uracil-xanthine permease; Region: ncs2; TIGR00801
866768002619	putative hypoxanthine oxidase; Provisional; Region: PRK09800
866768002620	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
866768002621	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
866768002622	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
866768002623	probable selenate reductase, FAD-binding subunit; Region: Se_sel_red_FAD; TIGR03312
866768002624	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
866768002625	putative selenium metabolism protein SsnA; Region: Se_ssnA; TIGR03314
866768002626	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
866768002627	active site
866768002628	putative substrate binding pocket [chemical binding]; other site
866768002629	putative selenate reductase subunit YgfK; Provisional; Region: PRK09853
866768002630	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
866768002631	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
866768002632	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
866768002633	GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function; Region: GT_2_like_f; cd04182
866768002634	Ligand binding site; other site
866768002635	metal-binding site
866768002636	probable selenium-dependent hydroxylase accessory protein YqeC; Region: TIGR03172
866768002637	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
866768002638	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
866768002639	XdhC Rossmann domain; Region: XdhC_C; pfam13478
866768002640	selenium-dependent molybdenum hydroxylase system protein, YqeB family; Region: matur_yqeB; TIGR03309
866768002641	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
866768002642	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
866768002643	carbamate kinase; Reviewed; Region: PRK12686
866768002644	putative substrate binding site [chemical binding]; other site
866768002645	homodimer interface [polypeptide binding]; other site
866768002646	nucleotide binding site [chemical binding]; other site
866768002647	nucleotide binding site [chemical binding]; other site
866768002648	D-hydantoinase; Region: D-hydantoinase; TIGR02033
866768002649	D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine...; Region: D-HYD; cd01314
866768002650	tetramer interface [polypeptide binding]; other site
866768002651	active site
866768002652	peptidase; Reviewed; Region: PRK13004
866768002653	M20 Peptidases with similarity to acetylornithine deacetylases and succinyl-diaminopimelate desuccinylases; Region: M20_ArgE_DapE_like4; cd05649
866768002654	putative metal binding site [ion binding]; other site
866768002655	putative dimer interface [polypeptide binding]; other site
866768002656	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
866768002657	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cd00640
866768002658	catalytic residue [active]
866768002659	aspartate/ornithine carbamoyltransferase family protein; Validated; Region: PRK07200
866768002660	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
866768002661	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
866768002662	GAF domain; Region: GAF; cl17456
866768002663	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
866768002664	PAS domain; Region: PAS; smart00091
866768002665	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866768002666	Walker A motif; other site
866768002667	ATP binding site [chemical binding]; other site
866768002668	Walker B motif; other site
866768002669	arginine finger; other site
866768002670	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
866768002671	xanthine dehydrogenase subunit XdhC; Provisional; Region: PRK09908
866768002672	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
866768002673	catalytic loop [active]
866768002674	iron binding site [ion binding]; other site
866768002675	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
866768002676	xanthine dehydrogenase subunit XdhB; Provisional; Region: PRK09971
866768002677	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
866768002678	xanthine dehydrogenase subunit XdhA; Provisional; Region: PRK09970
866768002679	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
866768002680	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
866768002681	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
866768002682	Peptidase family M23; Region: Peptidase_M23; pfam01551
866768002683	putative transposase OrfB; Reviewed; Region: PHA02517
866768002684	HTH-like domain; Region: HTH_21; pfam13276
866768002685	Integrase core domain; Region: rve; pfam00665
866768002686	Integrase core domain; Region: rve_2; pfam13333
866768002687	Transposase; Region: HTH_Tnp_1; cl17663
866768002688	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
866768002689	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
866768002690	serine transporter; Region: stp; TIGR00814
866768002691	putative acyltransferase; Provisional; Region: PRK05790
866768002692	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
866768002693	dimer interface [polypeptide binding]; other site
866768002694	active site
866768002695	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
866768002696	putative transposase OrfB; Reviewed; Region: PHA02517
866768002697	HTH-like domain; Region: HTH_21; pfam13276
866768002698	Integrase core domain; Region: rve; pfam00665
866768002699	Integrase core domain; Region: rve_2; pfam13333
866768002700	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
866768002701	Helix-turn-helix domain; Region: HTH_28; pfam13518
866768002702	Helix-turn-helix domain; Region: HTH_28; pfam13518
866768002703	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
866768002704	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768002705	putative substrate translocation pore; other site
866768002706	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768002707	putative racemase; Provisional; Region: PRK10200
866768002708	aspartate racemase; Region: asp_race; TIGR00035
866768002709	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
866768002710	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768002711	The C-terminal substrate binding domain of LysR, transcriptional regulator for lysine biosynthesis, contains the type 2 periplasmic binding fold; Region: PBP2_LysR; cd08456
866768002712	putative dimerization interface [polypeptide binding]; other site
866768002713	diaminopimelate decarboxylase; Provisional; Region: PRK11165
866768002714	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
866768002715	active site
866768002716	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
866768002717	substrate binding site [chemical binding]; other site
866768002718	catalytic residues [active]
866768002719	dimer interface [polypeptide binding]; other site
866768002720	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
866768002721	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
866768002722	DNA binding site [nucleotide binding]
866768002723	domain linker motif; other site
866768002724	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
866768002725	dimerization interface (closed form) [polypeptide binding]; other site
866768002726	ligand binding site [chemical binding]; other site
866768002727	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
866768002728	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
866768002729	putative acyl-acceptor binding pocket; other site
866768002730	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
866768002731	acyl-activating enzyme (AAE) consensus motif; other site
866768002732	putative AMP binding site [chemical binding]; other site
866768002733	lysophospholipid transporter LplT; Provisional; Region: PRK11195
866768002734	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768002735	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
866768002736	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
866768002737	active site
866768002738	catalytic tetrad [active]
866768002739	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
866768002740	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
866768002741	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
866768002742	putative DNA-binding cleft [nucleotide binding]; other site
866768002743	putative DNA clevage site; other site
866768002744	molecular lever; other site
866768002745	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
866768002746	putative active site [active]
866768002747	Ap4A binding site [chemical binding]; other site
866768002748	nudix motif; other site
866768002749	putative metal binding site [ion binding]; other site
866768002750	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
866768002751	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
866768002752	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
866768002753	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
866768002754	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
866768002755	prolipoprotein diacylglyceryl transferase; Region: lgt; TIGR00544
866768002756	thymidylate synthase; Reviewed; Region: thyA; PRK01827
866768002757	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
866768002758	dimerization interface [polypeptide binding]; other site
866768002759	active site
866768002760	hypothetical protein; Provisional; Region: PRK10506
866768002761	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
866768002762	hypothetical protein; Provisional; Region: PRK10557
866768002763	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
866768002764	hypothetical protein; Provisional; Region: PRK11521
866768002765	hypothetical protein; Provisional; Region: PRK10332
866768002766	Prepilin peptidase dependent protein C term (DUF3728); Region: DUF3728; pfam12528
866768002767	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
866768002768	exodeoxyribonuclease V, gamma subunit; Region: recC; TIGR01450
866768002769	protease3; Provisional; Region: PRK15101
866768002770	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
866768002771	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
866768002772	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
866768002773	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
866768002774	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
866768002775	AAA domain; Region: AAA_30; pfam13604
866768002776	Family description; Region: UvrD_C_2; pfam13538
866768002777	N-acetylglutamate synthase; Validated; Region: PRK05279
866768002778	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
866768002779	putative feedback inhibition sensing region; other site
866768002780	putative nucleotide binding site [chemical binding]; other site
866768002781	putative substrate binding site [chemical binding]; other site
866768002782	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
866768002783	Coenzyme A binding pocket [chemical binding]; other site
866768002784	AMIN domain; Region: AMIN; pfam11741
866768002785	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
866768002786	active site
866768002787	metal binding site [ion binding]; metal-binding site
866768002788	murein transglycosylase A; Provisional; Region: mltA; PRK11162
866768002789	MltA specific insert domain; Region: MltA; pfam03562
866768002790	3D domain; Region: 3D; pfam06725
866768002791	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
866768002792	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
866768002793	putative ATP binding site [chemical binding]; other site
866768002794	putative substrate interface [chemical binding]; other site
866768002795	CsdA-binding activator; Provisional; Region: PRK15019
866768002796	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
866768002797	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
866768002798	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
866768002799	catalytic residue [active]
866768002800	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
866768002801	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
866768002802	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768002803	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
866768002804	dimerization interface [polypeptide binding]; other site
866768002805	substrate binding pocket [chemical binding]; other site
866768002806	hypothetical protein; Provisional; Region: PRK10873
866768002807	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
866768002808	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
866768002809	DNA-binding transcriptional activator FucR; Provisional; Region: PRK10411
866768002810	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
866768002811	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
866768002812	L-fucose mutarotase; Provisional; Region: fucU; PRK15420
866768002813	L-fuculokinase; Provisional; Region: PRK10331
866768002814	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
866768002815	nucleotide binding site [chemical binding]; other site
866768002816	L-fucose isomerase; Provisional; Region: fucI; PRK10991
866768002817	L-fucose isomerase (FucIase); FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose during glycolysis). L-fucose (or 6-deoxy-L-galactose) is found in blood group...; Region: L-fucose_isomerase; cd03556
866768002818	hexamer (dimer of trimers) interface [polypeptide binding]; other site
866768002819	trimer interface [polypeptide binding]; other site
866768002820	substrate binding site [chemical binding]; other site
866768002821	Mn binding site [ion binding]; other site
866768002822	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
866768002823	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
866768002824	Walker A/P-loop; other site
866768002825	ATP binding site [chemical binding]; other site
866768002826	Q-loop/lid; other site
866768002827	ABC transporter signature motif; other site
866768002828	Walker B; other site
866768002829	D-loop; other site
866768002830	H-loop/switch region; other site
866768002831	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
866768002832	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
866768002833	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
866768002834	TM-ABC transporter signature motif; other site
866768002835	Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_2; cd06310
866768002836	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
866768002837	putative ligand binding site [chemical binding]; other site
866768002838	Ribulose kinase [Energy production and conversion]; Region: AraB; COG1069
866768002839	Yersinia Pseudotuberculosis carbohydrate kinase-like subgroup; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_YpCarbK_like; cd07782
866768002840	N- and C-terminal domain interface [polypeptide binding]; other site
866768002841	active site
866768002842	MgATP binding site [chemical binding]; other site
866768002843	catalytic site [active]
866768002844	metal binding site [ion binding]; metal-binding site
866768002845	carbohydrate binding site [chemical binding]; other site
866768002846	putative homodimer interface [polypeptide binding]; other site
866768002847	Transcriptional regulators [Transcription]; Region: PurR; COG1609
866768002848	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
866768002849	DNA binding site [nucleotide binding]
866768002850	domain linker motif; other site
866768002851	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
866768002852	dimerization interface [polypeptide binding]; other site
866768002853	ligand binding site [chemical binding]; other site
866768002854	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
866768002855	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
866768002856	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
866768002857	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
866768002858	L-1,2-propanediol oxidoreductase; Provisional; Region: PRK10624
866768002859	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
866768002860	dimer interface [polypeptide binding]; other site
866768002861	active site
866768002862	metal binding site [ion binding]; metal-binding site
866768002863	flap endonuclease-like protein; Provisional; Region: PRK09482
866768002864	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
866768002865	active site
866768002866	metal binding site 1 [ion binding]; metal-binding site
866768002867	putative 5' ssDNA interaction site; other site
866768002868	metal binding site 3; metal-binding site
866768002869	metal binding site 2 [ion binding]; metal-binding site
866768002870	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
866768002871	putative DNA binding site [nucleotide binding]; other site
866768002872	putative metal binding site [ion binding]; other site
866768002873	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
866768002874	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
866768002875	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
866768002876	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
866768002877	serine transporter; Region: stp; TIGR00814
866768002878	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
866768002879	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
866768002880	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
866768002881	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
866768002882	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
866768002883	SecY interacting protein Syd; Provisional; Region: PRK04968
866768002884	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3098
866768002885	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
866768002886	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
866768002887	probable active site [active]
866768002888	flavodoxin; Provisional; Region: PRK08105
866768002889	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768002890	D-galactonate transporter; Region: 2A0114; TIGR00893
866768002891	putative substrate translocation pore; other site
866768002892	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
866768002893	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
866768002894	active site
866768002895	tetramer interface [polypeptide binding]; other site
866768002896	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
866768002897	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
866768002898	active site
866768002899	tetramer interface [polypeptide binding]; other site
866768002900	hybrid sensory histidine kinase BarA; Provisional; Region: PRK11107
866768002901	Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984
866768002902	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
866768002903	dimerization interface [polypeptide binding]; other site
866768002904	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
866768002905	dimer interface [polypeptide binding]; other site
866768002906	phosphorylation site [posttranslational modification]
866768002907	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866768002908	ATP binding site [chemical binding]; other site
866768002909	Mg2+ binding site [ion binding]; other site
866768002910	G-X-G motif; other site
866768002911	Uncharacterized domain of BarA-like signal transduction histidine kinases [Signal transduction mechanisms]; Region: COG4999
866768002912	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768002913	active site
866768002914	phosphorylation site [posttranslational modification]
866768002915	intermolecular recognition site; other site
866768002916	dimerization interface [polypeptide binding]; other site
866768002917	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
866768002918	putative binding surface; other site
866768002919	active site
866768002920	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
866768002921	TRAM domain; Region: TRAM; pfam01938
866768002922	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768002923	S-adenosylmethionine binding site [chemical binding]; other site
866768002924	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
866768002925	HD domain; Region: HD_4; pfam13328
866768002926	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
866768002927	synthetase active site [active]
866768002928	NTP binding site [chemical binding]; other site
866768002929	metal binding site [ion binding]; metal-binding site
866768002930	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
866768002931	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
866768002932	antitoxin MazE; Provisional; Region: PRK09798
866768002933	toxin MazF; Provisional; Region: PRK09907
866768002934	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
866768002935	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
866768002936	homodimer interface [polypeptide binding]; other site
866768002937	metal binding site [ion binding]; metal-binding site
866768002938	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
866768002939	homodimer interface [polypeptide binding]; other site
866768002940	active site
866768002941	putative chemical substrate binding site [chemical binding]; other site
866768002942	metal binding site [ion binding]; metal-binding site
866768002943	CTP synthetase; Validated; Region: pyrG; PRK05380
866768002944	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
866768002945	Catalytic site [active]
866768002946	active site
866768002947	UTP binding site [chemical binding]; other site
866768002948	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
866768002949	active site
866768002950	putative oxyanion hole; other site
866768002951	catalytic triad [active]
866768002952	enolase; Provisional; Region: eno; PRK00077
866768002953	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
866768002954	dimer interface [polypeptide binding]; other site
866768002955	metal binding site [ion binding]; metal-binding site
866768002956	substrate binding pocket [chemical binding]; other site
866768002957	Beta-propeller domains of methanol dehydrogenase type [General function prediction only]; Region: COG1512
866768002958	Repair protein; Region: Repair_PSII; pfam04536
866768002959	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
866768002960	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
866768002961	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
866768002962	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
866768002963	nucleotide binding site [chemical binding]; other site
866768002964	Major Facilitator Superfamily; Region: MFS_1; pfam07690
866768002965	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768002966	2-deoxy-D-gluconate 3-dehydrogenase; Provisional; Region: PRK06935
866768002967	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
866768002968	NADP binding site [chemical binding]; other site
866768002969	homodimer interface [polypeptide binding]; other site
866768002970	active site
866768002971	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
866768002972	FAD binding domain; Region: FAD_binding_4; pfam01565
866768002973	benzoate transport; Region: 2A0115; TIGR00895
866768002974	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768002975	putative substrate translocation pore; other site
866768002976	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
866768002977	Ligand binding site [chemical binding]; other site
866768002978	Electron transfer flavoprotein domain; Region: ETF; pfam01012
866768002979	Protein of unknown function (DUF2950); Region: DUF2950; pfam11453
866768002980	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
866768002981	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
866768002982	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
866768002983	Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription]; Region: GlpP; COG1954
866768002984	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
866768002985	putative oxidoreductase FixC; Provisional; Region: PRK10157
866768002986	6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a...; Region: PTPS; cd00470
866768002987	homohexamer interface [polypeptide binding]; other site
866768002988	putative substrate stabilizing pore; other site
866768002989	pterin binding site; other site
866768002990	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
866768002991	Flavodoxin; Region: Flavodoxin_1; pfam00258
866768002992	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
866768002993	FAD binding pocket [chemical binding]; other site
866768002994	FAD binding motif [chemical binding]; other site
866768002995	catalytic residues [active]
866768002996	NAD binding pocket [chemical binding]; other site
866768002997	phosphate binding motif [ion binding]; other site
866768002998	beta-alpha-beta structure motif; other site
866768002999	sulfite reductase subunit beta; Provisional; Region: PRK13504
866768003000	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
866768003001	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
866768003002	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
866768003003	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
866768003004	Active Sites [active]
866768003005	Hok/gef family; Region: HOK_GEF; pfam01848
866768003006	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
866768003007	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
866768003008	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
866768003009	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
866768003010	metal binding site [ion binding]; metal-binding site
866768003011	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
866768003012	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
866768003013	Active Sites [active]
866768003014	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
866768003015	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
866768003016	CysD dimerization site [polypeptide binding]; other site
866768003017	G1 box; other site
866768003018	putative GEF interaction site [polypeptide binding]; other site
866768003019	GTP/Mg2+ binding site [chemical binding]; other site
866768003020	Switch I region; other site
866768003021	G2 box; other site
866768003022	G3 box; other site
866768003023	Switch II region; other site
866768003024	G4 box; other site
866768003025	G5 box; other site
866768003026	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
866768003027	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
866768003028	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
866768003029	ligand-binding site [chemical binding]; other site
866768003030	Protein of unknown function (DUF3561); Region: DUF3561; pfam12084
866768003031	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
866768003032	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
866768003033	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
866768003034	substrate binding site; other site
866768003035	dimer interface; other site
866768003036	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
866768003037	homotrimer interaction site [polypeptide binding]; other site
866768003038	zinc binding site [ion binding]; other site
866768003039	CDP-binding sites; other site
866768003040	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
866768003041	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
866768003042	Permutation of conserved domain; other site
866768003043	active site
866768003044	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
866768003045	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
866768003046	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768003047	S-adenosylmethionine binding site [chemical binding]; other site
866768003048	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
866768003049	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
866768003050	Peptidase family M23; Region: Peptidase_M23; pfam01551
866768003051	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
866768003052	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
866768003053	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
866768003054	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
866768003055	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
866768003056	DNA binding residues [nucleotide binding]
866768003057	putative transporter; Provisional; Region: PRK09821
866768003058	GntP family permease; Region: GntP_permease; pfam02447
866768003059	hypothetical protein; Provisional; Region: PRK09989
866768003060	putative aldolase; Validated; Region: PRK08130
866768003061	active site
866768003062	intersubunit interface [polypeptide binding]; other site
866768003063	Zn2+ binding site [ion binding]; other site
866768003064	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
866768003065	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
866768003066	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
866768003067	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
866768003068	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
866768003069	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
866768003070	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
866768003071	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
866768003072	active site
866768003073	metal binding site [ion binding]; metal-binding site
866768003074	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
866768003075	MutS domain I; Region: MutS_I; pfam01624
866768003076	MutS domain II; Region: MutS_II; pfam05188
866768003077	MutS domain III; Region: MutS_III; pfam05192
866768003078	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
866768003079	Walker A/P-loop; other site
866768003080	ATP binding site [chemical binding]; other site
866768003081	Q-loop/lid; other site
866768003082	ABC transporter signature motif; other site
866768003083	Walker B; other site
866768003084	D-loop; other site
866768003085	H-loop/switch region; other site
866768003086	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
866768003087	formate hydrogenlyase transcriptional activator FhlA; Provisional; Region: PRK15429
866768003088	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
866768003089	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
866768003090	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866768003091	Walker A motif; other site
866768003092	ATP binding site [chemical binding]; other site
866768003093	Walker B motif; other site
866768003094	arginine finger; other site
866768003095	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
866768003096	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
866768003097	dimerization interface [polypeptide binding]; other site
866768003098	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
866768003099	ATP binding site [chemical binding]; other site
866768003100	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
866768003101	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
866768003102	hydrogenase assembly chaperone; Provisional; Region: PRK10409
866768003103	hydrogenase nickel incorporation protein HypB; Provisional; Region: PRK10463
866768003104	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
866768003105	hydrogenase nickel incorporation protein; Validated; Region: hypA; PRK03681
866768003106	formate hydrogenlyase regulatory protein HycA; Provisional; Region: PRK10198
866768003107	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
866768003108	formate hydrogenlyase subunit 3; Reviewed; Region: PRK08042
866768003109	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
866768003110	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
866768003111	NADH dehydrogenase; Region: NADHdh; cl00469
866768003112	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
866768003113	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
866768003114	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
866768003115	formate hydrogenlyase complex iron-sulfur subunit; Provisional; Region: PRK12387
866768003116	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
866768003117	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
866768003118	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
866768003119	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
866768003120	nickel binding site [ion binding]; other site
866768003121	cryptic 6-phospho-beta-glucosidase; Provisional; Region: PRK09852
866768003122	beta-galactosidase; Region: BGL; TIGR03356
866768003123	PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC; Provisional; Region: PRK09796
866768003124	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
866768003125	active site turn [active]
866768003126	phosphorylation site [posttranslational modification]
866768003127	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
866768003128	Transcriptional regulators [Transcription]; Region: PurR; COG1609
866768003129	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
866768003130	DNA binding site [nucleotide binding]
866768003131	domain linker motif; other site
866768003132	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
866768003133	dimerization interface (closed form) [polypeptide binding]; other site
866768003134	ligand binding site [chemical binding]; other site
866768003135	formate dehydrogenase-H ferredoxin subunit; Provisional; Region: PRK10330
866768003136	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
866768003137	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
866768003138	Acylphosphatase; Region: Acylphosphatase; pfam00708
866768003139	HypF finger; Region: zf-HYPF; pfam07503
866768003140	HypF finger; Region: zf-HYPF; pfam07503
866768003141	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
866768003142	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
866768003143	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
866768003144	anaerobic nitric oxide reductase flavorubredoxin; Provisional; Region: PRK05452
866768003145	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
866768003146	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
866768003147	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
866768003148	iron binding site [ion binding]; other site
866768003149	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
866768003150	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
866768003151	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866768003152	Walker A motif; other site
866768003153	ATP binding site [chemical binding]; other site
866768003154	Walker B motif; other site
866768003155	arginine finger; other site
866768003156	D-arabinose 5-phosphate isomerase; Provisional; Region: gutQ; PRK11543
866768003157	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
866768003158	putative active site [active]
866768003159	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
866768003160	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
866768003161	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
866768003162	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
866768003163	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
866768003164	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
866768003165	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
866768003166	putative NAD(P) binding site [chemical binding]; other site
866768003167	active site
866768003168	PTS system glucitol/sorbitol-specific transporter subunit IIA; Provisional; Region: PRK10377
866768003169	PTS system, glucitol/sorbitol-specific, IIBC component; Region: EIIBC-GUT; TIGR00825
866768003170	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
866768003171	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
866768003172	PTS system, glucitol/sorbitol-specific, IIC component; Region: EII-GUT; TIGR00821
866768003173	Transglycosylase SLT domain; Region: SLT_2; pfam13406
866768003174	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
866768003175	N-acetyl-D-glucosamine binding site [chemical binding]; other site
866768003176	hypothetical protein; Validated; Region: PRK03661
866768003177	recombinase A; Provisional; Region: recA; PRK09354
866768003178	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
866768003179	hexamer interface [polypeptide binding]; other site
866768003180	Walker A motif; other site
866768003181	ATP binding site [chemical binding]; other site
866768003182	Walker B motif; other site
866768003183	recombination regulator RecX; Reviewed; Region: recX; PRK00117
866768003184	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
866768003185	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
866768003186	motif 1; other site
866768003187	active site
866768003188	motif 2; other site
866768003189	motif 3; other site
866768003190	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
866768003191	DHHA1 domain; Region: DHHA1; pfam02272
866768003192	carbon storage regulator; Provisional; Region: PRK01712
866768003193	fructose-1-P/6-phosphogluconate phosphatase; Provisional; Region: PRK10725
866768003194	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866768003195	motif II; other site
866768003196	Predicted membrane protein [Function unknown]; Region: COG1238
866768003197	glutamate--cysteine ligase; Provisional; Region: PRK02107
866768003198	S-ribosylhomocysteinase; Provisional; Region: PRK02260
866768003199	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
866768003200	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768003201	putative substrate translocation pore; other site
866768003202	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768003203	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
866768003204	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
866768003205	HlyD family secretion protein; Region: HlyD_3; pfam13437
866768003206	transcriptional repressor MprA; Provisional; Region: PRK10870
866768003207	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
866768003208	putative L-valine exporter; Provisional; Region: PRK10408
866768003209	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
866768003210	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
866768003211	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768003212	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
866768003213	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
866768003214	glycine betaine transporter membrane protein; Provisional; Region: PRK10952
866768003215	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768003216	dimer interface [polypeptide binding]; other site
866768003217	conserved gate region; other site
866768003218	putative PBP binding loops; other site
866768003219	ABC-ATPase subunit interface; other site
866768003220	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
866768003221	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
866768003222	Walker A/P-loop; other site
866768003223	ATP binding site [chemical binding]; other site
866768003224	Q-loop/lid; other site
866768003225	ABC transporter signature motif; other site
866768003226	Walker B; other site
866768003227	D-loop; other site
866768003228	H-loop/switch region; other site
866768003229	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
866768003230	ribonucleotide-diphosphate reductase subunit beta; Provisional; Region: nrdF2; PRK13966
866768003231	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
866768003232	dimer interface [polypeptide binding]; other site
866768003233	putative radical transfer pathway; other site
866768003234	diiron center [ion binding]; other site
866768003235	tyrosyl radical; other site
866768003236	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
866768003237	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
866768003238	Class I ribonucleotide reductase; Region: RNR_I; cd01679
866768003239	active site
866768003240	dimer interface [polypeptide binding]; other site
866768003241	catalytic residues [active]
866768003242	effector binding site; other site
866768003243	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
866768003244	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
866768003245	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
866768003246	catalytic residues [active]
866768003247	hypothetical protein; Provisional; Region: PRK10132
866768003248	hypothetical protein; Provisional; Region: PRK10556
866768003249	Protein of unknown function (DUF1144); Region: DUF1144; pfam06610
866768003250	DNA binding protein, nucleoid-associated; Provisional; Region: PRK10328
866768003251	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
866768003252	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YgaP, and similar uncharacterized putative rhodanese-related sulfurtransferases; Region: RHOD_YgaP; cd01527
866768003253	active site residue [active]
866768003254	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
866768003255	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
866768003256	dimerization interface [polypeptide binding]; other site
866768003257	putative DNA binding site [nucleotide binding]; other site
866768003258	Transcriptional regulators [Transcription]; Region: MarR; COG1846
866768003259	putative Zn2+ binding site [ion binding]; other site
866768003260	Uncharacterized homolog of Blt101 [Function unknown]; Region: COG0401
866768003261	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
866768003262	bacterial OsmY and nodulation domain; Region: BON; smart00749
866768003263	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
866768003264	DNA-binding transcriptional regulator CsiR; Provisional; Region: PRK11534
866768003265	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
866768003266	DNA-binding site [nucleotide binding]; DNA binding site
866768003267	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
866768003268	gamma-aminobutyrate transporter; Provisional; Region: PRK10197
866768003269	4-aminobutyrate aminotransferase; Validated; Region: PRK08088
866768003270	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
866768003271	inhibitor-cofactor binding pocket; inhibition site
866768003272	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768003273	catalytic residue [active]
866768003274	succinate-semialdehyde dehydrogenase I; Provisional; Region: gabD; PRK11241
866768003275	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
866768003276	tetramerization interface [polypeptide binding]; other site
866768003277	NAD(P) binding site [chemical binding]; other site
866768003278	catalytic residues [active]
866768003279	Predicted dehydrogenase [General function prediction only]; Region: COG0579
866768003280	hydroxyglutarate oxidase; Provisional; Region: PRK11728
866768003281	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cd00250
866768003282	substrate binding pocket [chemical binding]; other site
866768003283	active site
866768003284	iron coordination sites [ion binding]; other site
866768003285	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
866768003286	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
866768003287	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
866768003288	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
866768003289	ParB-like nuclease domain; Region: ParB; smart00470
866768003290	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
866768003291	RepB plasmid partitioning protein; Region: RepB; pfam07506
866768003292	ParB-like nuclease domain; Region: ParBc; pfam02195
866768003293	RepB plasmid partitioning protein; Region: RepB; pfam07506
866768003294	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
866768003295	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
866768003296	catalytic residues [active]
866768003297	catalytic nucleophile [active]
866768003298	Recombinase; Region: Recombinase; pfam07508
866768003299	integrase; Provisional; Region: PRK09692
866768003300	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
866768003301	active site
866768003302	Int/Topo IB signature motif; other site
866768003303	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
866768003304	SmpB-tmRNA interface; other site
866768003305	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
866768003306	putative coenzyme Q binding site [chemical binding]; other site
866768003307	hypothetical protein; Validated; Region: PRK01777
866768003308	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
866768003309	SmpA / OmlA family; Region: SmpA_OmlA; pfam04355
866768003310	recombination and repair protein; Provisional; Region: PRK10869
866768003311	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
866768003312	Walker A/P-loop; other site
866768003313	ATP binding site [chemical binding]; other site
866768003314	Q-loop/lid; other site
866768003315	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
866768003316	Q-loop/lid; other site
866768003317	ABC transporter signature motif; other site
866768003318	Walker B; other site
866768003319	D-loop; other site
866768003320	H-loop/switch region; other site
866768003321	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
866768003322	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK02231
866768003323	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
866768003324	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
866768003325	dimer interface [polypeptide binding]; other site
866768003326	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
866768003327	hypothetical protein; Provisional; Region: PRK11573
866768003328	Domain of unknown function DUF21; Region: DUF21; pfam01595
866768003329	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
866768003330	Transporter associated domain; Region: CorC_HlyC; smart01091
866768003331	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
866768003332	signal recognition particle protein; Provisional; Region: PRK10867
866768003333	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
866768003334	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
866768003335	P loop; other site
866768003336	GTP binding site [chemical binding]; other site
866768003337	Signal peptide binding domain; Region: SRP_SPB; pfam02978
866768003338	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
866768003339	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
866768003340	RimM N-terminal domain; Region: RimM; pfam01782
866768003341	PRC-barrel domain; Region: PRC; pfam05239
866768003342	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
866768003343	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
866768003344	putative outer membrane lipoprotein; Provisional; Region: PRK09967
866768003345	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
866768003346	ligand binding site [chemical binding]; other site
866768003347	putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966
866768003348	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
866768003349	metal binding site [ion binding]; metal-binding site
866768003350	active site
866768003351	I-site; other site
866768003352	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
866768003353	lipoprotein; Provisional; Region: PRK11443
866768003354	Protein of unknown function (DUF2799); Region: DUF2799; pfam10973
866768003355	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
866768003356	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
866768003357	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
866768003358	chorismate mutase domain of T-protein; Region: CM_T; TIGR01799
866768003359	prephenate dehydrogenase; Validated; Region: PRK08507
866768003360	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
866768003361	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
866768003362	Prephenate dehydratase; Region: PDT; pfam00800
866768003363	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
866768003364	putative L-Phe binding site [chemical binding]; other site
866768003365	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
866768003366	30S subunit binding site; other site
866768003367	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
866768003368	Protein of unknown function (DUF3897); Region: DUF3897; cl17494
866768003369	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
866768003370	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
866768003371	RNA binding surface [nucleotide binding]; other site
866768003372	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
866768003373	active site
866768003374	hypothetical protein; Provisional; Region: PRK10723
866768003375	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
866768003376	protein disaggregation chaperone; Provisional; Region: PRK10865
866768003377	Clp amino terminal domain; Region: Clp_N; pfam02861
866768003378	Clp amino terminal domain; Region: Clp_N; pfam02861
866768003379	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866768003380	Walker A motif; other site
866768003381	ATP binding site [chemical binding]; other site
866768003382	Walker B motif; other site
866768003383	arginine finger; other site
866768003384	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866768003385	Walker A motif; other site
866768003386	ATP binding site [chemical binding]; other site
866768003387	Walker B motif; other site
866768003388	arginine finger; other site
866768003389	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
866768003390	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
866768003391	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768003392	putative substrate translocation pore; other site
866768003393	lipoprotein; Provisional; Region: PRK10759
866768003394	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
866768003395	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
866768003396	domain interface [polypeptide binding]; other site
866768003397	putative active site [active]
866768003398	catalytic site [active]
866768003399	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
866768003400	domain interface [polypeptide binding]; other site
866768003401	putative active site [active]
866768003402	catalytic site [active]
866768003403	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
866768003404	CoA binding domain; Region: CoA_binding_2; pfam13380
866768003405	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
866768003406	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
866768003407	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
866768003408	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
866768003409	Uncharacterized conserved protein [Function unknown]; Region: COG3148
866768003410	thioredoxin 2; Provisional; Region: PRK10996
866768003411	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
866768003412	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
866768003413	catalytic residues [active]
866768003414	putative methyltransferase; Provisional; Region: PRK10864
866768003415	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
866768003416	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
866768003417	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
866768003418	ligand binding site [chemical binding]; other site
866768003419	active site
866768003420	UGI interface [polypeptide binding]; other site
866768003421	catalytic site [active]
866768003422	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
866768003423	cysteine/O-acetylserine exporter; Provisional; Region: PRK10323
866768003424	Transcriptional regulator [Transcription]; Region: LysR; COG0583
866768003425	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768003426	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
866768003427	dimerization interface [polypeptide binding]; other site
866768003428	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
866768003429	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
866768003430	ATP binding site [chemical binding]; other site
866768003431	Mg++ binding site [ion binding]; other site
866768003432	motif III; other site
866768003433	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
866768003434	nucleotide binding region [chemical binding]; other site
866768003435	ATP-binding site [chemical binding]; other site
866768003436	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
866768003437	Methyltransferase domain; Region: Methyltransf_26; pfam13659
866768003438	L-aspartate oxidase; Provisional; Region: PRK09077
866768003439	L-aspartate oxidase; Provisional; Region: PRK06175
866768003440	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
866768003441	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
866768003442	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
866768003443	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
866768003444	DNA binding residues [nucleotide binding]
866768003445	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
866768003446	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
866768003447	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
866768003448	Negative regulator of sigma E activity [Signal transduction mechanisms]; Region: RseB; COG3026
866768003449	anti-sigma E factor; Provisional; Region: rseB; PRK09455
866768003450	SoxR reducing system protein RseC; Provisional; Region: PRK10862
866768003451	GTP-binding protein LepA; Provisional; Region: PRK05433
866768003452	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
866768003453	G1 box; other site
866768003454	putative GEF interaction site [polypeptide binding]; other site
866768003455	GTP/Mg2+ binding site [chemical binding]; other site
866768003456	Switch I region; other site
866768003457	G2 box; other site
866768003458	G3 box; other site
866768003459	Switch II region; other site
866768003460	G4 box; other site
866768003461	G5 box; other site
866768003462	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
866768003463	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
866768003464	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
866768003465	signal peptidase I; Provisional; Region: PRK10861
866768003466	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
866768003467	Catalytic site [active]
866768003468	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
866768003469	ribonuclease III; Reviewed; Region: rnc; PRK00102
866768003470	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
866768003471	dimerization interface [polypeptide binding]; other site
866768003472	active site
866768003473	metal binding site [ion binding]; metal-binding site
866768003474	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
866768003475	dsRNA binding site [nucleotide binding]; other site
866768003476	GTPase Era; Reviewed; Region: era; PRK00089
866768003477	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
866768003478	G1 box; other site
866768003479	GTP/Mg2+ binding site [chemical binding]; other site
866768003480	Switch I region; other site
866768003481	G2 box; other site
866768003482	Switch II region; other site
866768003483	G3 box; other site
866768003484	G4 box; other site
866768003485	G5 box; other site
866768003486	KH domain; Region: KH_2; pfam07650
866768003487	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
866768003488	Recombination protein O N terminal; Region: RecO_N; pfam11967
866768003489	Recombination protein O C terminal; Region: RecO_C; pfam02565
866768003490	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
866768003491	active site
866768003492	hydrophilic channel; other site
866768003493	dimerization interface [polypeptide binding]; other site
866768003494	catalytic residues [active]
866768003495	active site lid [active]
866768003496	holo-[acyl-carrier-protein] synthase; Region: acpS; TIGR00516
866768003497	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
866768003498	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
866768003499	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
866768003500	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
866768003501	putative active site [active]
866768003502	hypothetical protein; Provisional; Region: PRK11590
866768003503	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
866768003504	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
866768003505	nucleoside/Zn binding site; other site
866768003506	dimer interface [polypeptide binding]; other site
866768003507	catalytic motif [active]
866768003508	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
866768003509	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
866768003510	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
866768003511	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
866768003512	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
866768003513	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
866768003514	substrate binding pocket [chemical binding]; other site
866768003515	membrane-bound complex binding site; other site
866768003516	hinge residues; other site
866768003517	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
866768003518	N-acetyl-D-glucosamine binding site [chemical binding]; other site
866768003519	catalytic residue [active]
866768003520	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
866768003521	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
866768003522	dimerization interface [polypeptide binding]; other site
866768003523	ATP binding site [chemical binding]; other site
866768003524	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
866768003525	dimerization interface [polypeptide binding]; other site
866768003526	ATP binding site [chemical binding]; other site
866768003527	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
866768003528	putative active site [active]
866768003529	catalytic triad [active]
866768003530	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
866768003531	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
866768003532	dimer interface [polypeptide binding]; other site
866768003533	phosphorylation site [posttranslational modification]
866768003534	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866768003535	ATP binding site [chemical binding]; other site
866768003536	Mg2+ binding site [ion binding]; other site
866768003537	G-X-G motif; other site
866768003538	hypothetical protein; Provisional; Region: PRK10722
866768003539	response regulator GlrR; Provisional; Region: PRK15115
866768003540	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768003541	active site
866768003542	phosphorylation site [posttranslational modification]
866768003543	intermolecular recognition site; other site
866768003544	dimerization interface [polypeptide binding]; other site
866768003545	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866768003546	Walker A motif; other site
866768003547	ATP binding site [chemical binding]; other site
866768003548	Walker B motif; other site
866768003549	arginine finger; other site
866768003550	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
866768003551	Nitrogen regulatory protein P-II; Region: P-II; smart00938
866768003552	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
866768003553	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
866768003554	heme-binding site [chemical binding]; other site
866768003555	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
866768003556	FAD binding pocket [chemical binding]; other site
866768003557	FAD binding motif [chemical binding]; other site
866768003558	phosphate binding motif [ion binding]; other site
866768003559	beta-alpha-beta structure motif; other site
866768003560	NAD binding pocket [chemical binding]; other site
866768003561	Heme binding  pocket [chemical binding]; other site
866768003562	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
866768003563	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
866768003564	dimer interface [polypeptide binding]; other site
866768003565	active site
866768003566	glycine-pyridoxal phosphate binding site [chemical binding]; other site
866768003567	folate binding site [chemical binding]; other site
866768003568	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
866768003569	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
866768003570	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
866768003571	nucleotide binding site [chemical binding]; other site
866768003572	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
866768003573	TPR motif; other site
866768003574	Tetratricopeptide repeat; Region: TPR_16; pfam13432
866768003575	binding surface
866768003576	TPR repeat; Region: TPR_11; pfam13414
866768003577	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
866768003578	TPR motif; other site
866768003579	binding surface
866768003580	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
866768003581	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
866768003582	ligand binding site [chemical binding]; other site
866768003583	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
866768003584	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
866768003585	Walker A/P-loop; other site
866768003586	ATP binding site [chemical binding]; other site
866768003587	Q-loop/lid; other site
866768003588	ABC transporter signature motif; other site
866768003589	Walker B; other site
866768003590	D-loop; other site
866768003591	H-loop/switch region; other site
866768003592	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
866768003593	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
866768003594	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
866768003595	TM-ABC transporter signature motif; other site
866768003596	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
866768003597	L-threonine dehydrogenase (TDH)-like; Region: THR_DH_like; cd08239
866768003598	putative NAD(P) binding site [chemical binding]; other site
866768003599	catalytic Zn binding site [ion binding]; other site
866768003600	aldose 1-epimerase, similar to Escherichia coli YphB; Region: Aldose_epim_Ec_YphB; cd09021
866768003601	active site
866768003602	catalytic residues [active]
866768003603	Predicted membrane protein [Function unknown]; Region: COG2259
866768003604	phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional; Region: PRK09754
866768003605	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
866768003606	2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase; Provisional; Region: PRK06200
866768003607	cis-biphenyl-2,3-dihydrodiol-2,3-dehydrogenase (BphB)-like, classical (c) SDRs; Region: BphB-like_SDR_c; cd05348
866768003608	NAD binding site [chemical binding]; other site
866768003609	active site
866768003610	Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO). The RO family comprise a...; Region: Rieske_RO_ferredoxin; cd03528
866768003611	[2Fe-2S] cluster binding site [ion binding]; other site
866768003612	Ring hydroxylating dioxygenase beta subunit. This subunit has a similar structure to NTF-2, Ketosteroid isomerase and scytalone dehydratase.The degradation of aromatic compounds by aerobic bacteria frequently begins with the dihydroxylation of the...; Region: ring_hydroxylating_dioxygenases_beta; cd00667
866768003613	inter-subunit interface; other site
866768003614	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
866768003615	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
866768003616	iron-sulfur cluster [ion binding]; other site
866768003617	[2Fe-2S] cluster binding site [ion binding]; other site
866768003618	C-terminal catalytic domain of the oxygenase alpha subunit of naphthalene 1,2-dioxygenase (NDO) and related aromatic ring hydroxylating dioxygenases; Region: RHO_alpha_C_NDO-like; cd08881
866768003619	beta subunit interface [polypeptide binding]; other site
866768003620	alpha subunit interface [polypeptide binding]; other site
866768003621	active site
866768003622	substrate binding site [chemical binding]; other site
866768003623	Fe binding site [ion binding]; other site
866768003624	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
866768003625	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768003626	The C-terminal substrate binding domain of LysR-type transcriptional regulator HcaR in involved in 3-phenylpropionic acid catabolism, contains the type2 periplasmic binding fold; Region: PBP2_HcaR; cd08450
866768003627	putative dimerization interface [polypeptide binding]; other site
866768003628	putative substrate binding pocket [chemical binding]; other site
866768003629	putative 3-phenylpropionic acid transporter; Provisional; Region: PRK11128
866768003630	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768003631	putative substrate translocation pore; other site
866768003632	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
866768003633	PRD domain; Region: PRD; pfam00874
866768003634	PRD domain; Region: PRD; pfam00874
866768003635	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
866768003636	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
866768003637	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
866768003638	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
866768003639	active site
866768003640	dimerization interface [polypeptide binding]; other site
866768003641	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
866768003642	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
866768003643	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
866768003644	Rrf2 family protein; Region: rrf2_super; TIGR00738
866768003645	cysteine desulfurase; Provisional; Region: PRK14012
866768003646	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
866768003647	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
866768003648	catalytic residue [active]
866768003649	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
866768003650	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
866768003651	trimerization site [polypeptide binding]; other site
866768003652	active site
866768003653	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
866768003654	co-chaperone HscB; Provisional; Region: hscB; PRK05014
866768003655	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
866768003656	HSP70 interaction site [polypeptide binding]; other site
866768003657	HSCB C-terminal oligomerisation domain; Region: HSCB_C; pfam07743
866768003658	chaperone protein HscA; Provisional; Region: hscA; PRK05183
866768003659	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
866768003660	nucleotide binding site [chemical binding]; other site
866768003661	putative NEF/HSP70 interaction site [polypeptide binding]; other site
866768003662	SBD interface [polypeptide binding]; other site
866768003663	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
866768003664	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
866768003665	catalytic loop [active]
866768003666	iron binding site [ion binding]; other site
866768003667	hypothetical protein; Provisional; Region: PRK10721
866768003668	aminopeptidase B; Provisional; Region: PRK05015
866768003669	Peptidase; Region: DUF3663; pfam12404
866768003670	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
866768003671	interface (dimer of trimers) [polypeptide binding]; other site
866768003672	Substrate-binding/catalytic site; other site
866768003673	Zn-binding sites [ion binding]; other site
866768003674	enhanced serine sensitivity protein SseB; Provisional; Region: PRK11611
866768003675	putative transposase OrfB; Reviewed; Region: PHA02517
866768003676	HTH-like domain; Region: HTH_21; pfam13276
866768003677	Integrase core domain; Region: rve; pfam00665
866768003678	Integrase core domain; Region: rve_2; pfam13333
866768003679	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
866768003680	Helix-turn-helix domain; Region: HTH_28; pfam13518
866768003681	Helix-turn-helix domain; Region: HTH_28; pfam13518
866768003682	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
866768003683	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
866768003684	active site residue [active]
866768003685	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
866768003686	active site residue [active]
866768003687	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
866768003688	MG2 domain; Region: A2M_N; pfam01835
866768003689	Alpha-2-macroglobulin family; Region: A2M; pfam00207
866768003690	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
866768003691	surface patch; other site
866768003692	thioester region; other site
866768003693	specificity defining residues; other site
866768003694	penicillin-binding protein 1C; Provisional; Region: PRK11240
866768003695	Transglycosylase; Region: Transgly; pfam00912
866768003696	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
866768003697	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
866768003698	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
866768003699	active site
866768003700	multimer interface [polypeptide binding]; other site
866768003701	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK11194
866768003702	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866768003703	FeS/SAM binding site; other site
866768003704	cytoskeletal protein RodZ; Provisional; Region: PRK10856
866768003705	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
866768003706	non-specific DNA binding site [nucleotide binding]; other site
866768003707	salt bridge; other site
866768003708	sequence-specific DNA binding site [nucleotide binding]; other site
866768003709	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
866768003710	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
866768003711	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
866768003712	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
866768003713	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
866768003714	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
866768003715	dimer interface [polypeptide binding]; other site
866768003716	motif 1; other site
866768003717	active site
866768003718	motif 2; other site
866768003719	motif 3; other site
866768003720	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
866768003721	anticodon binding site; other site
866768003722	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
866768003723	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
866768003724	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cd00216
866768003725	Trp docking motif [polypeptide binding]; other site
866768003726	active site
866768003727	GTP-binding protein Der; Reviewed; Region: PRK00093
866768003728	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
866768003729	G1 box; other site
866768003730	GTP/Mg2+ binding site [chemical binding]; other site
866768003731	Switch I region; other site
866768003732	G2 box; other site
866768003733	Switch II region; other site
866768003734	G3 box; other site
866768003735	G4 box; other site
866768003736	G5 box; other site
866768003737	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
866768003738	G1 box; other site
866768003739	GTP/Mg2+ binding site [chemical binding]; other site
866768003740	Switch I region; other site
866768003741	G2 box; other site
866768003742	G3 box; other site
866768003743	Switch II region; other site
866768003744	G4 box; other site
866768003745	G5 box; other site
866768003746	Protein of unknown function (DUF1407); Region: DUF1407; pfam07191
866768003747	exodeoxyribonuclease VII, large subunit; Region: xseA; TIGR00237
866768003748	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
866768003749	generic binding surface II; other site
866768003750	generic binding surface I; other site
866768003751	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
866768003752	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
866768003753	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
866768003754	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
866768003755	active site
866768003756	GMP synthase; Reviewed; Region: guaA; PRK00074
866768003757	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
866768003758	AMP/PPi binding site [chemical binding]; other site
866768003759	candidate oxyanion hole; other site
866768003760	catalytic triad [active]
866768003761	potential glutamine specificity residues [chemical binding]; other site
866768003762	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
866768003763	ATP Binding subdomain [chemical binding]; other site
866768003764	Ligand Binding sites [chemical binding]; other site
866768003765	Dimerization subdomain; other site
866768003766	Glycine zipper 2TM domain; Region: Rick_17kDa_Anti; cl10470
866768003767	Protein of unknown function (DUF2633); Region: DUF2633; pfam11119
866768003768	MASE1; Region: MASE1; pfam05231
866768003769	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
866768003770	diguanylate cyclase; Region: GGDEF; smart00267
866768003771	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
866768003772	exopolyphosphatase; Provisional; Region: PRK10854
866768003773	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
866768003774	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
866768003775	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
866768003776	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
866768003777	Catalytic C-terminal domain, first repeat, of prokaryotic polyphosphate kinase 1 and similar proteins; Region: PLDc_PPK1_C1; cd09114
866768003778	domain interface [polypeptide binding]; other site
866768003779	active site
866768003780	catalytic site [active]
866768003781	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
866768003782	putative active site [active]
866768003783	catalytic site [active]
866768003784	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
866768003785	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
866768003786	active site
866768003787	substrate binding site [chemical binding]; other site
866768003788	cosubstrate binding site; other site
866768003789	catalytic site [active]
866768003790	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
866768003791	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
866768003792	dimerization interface [polypeptide binding]; other site
866768003793	putative ATP binding site [chemical binding]; other site
866768003794	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
866768003795	active site
866768003796	uracil transporter; Provisional; Region: PRK10720
866768003797	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
866768003798	DNA replication initiation factor; Provisional; Region: PRK08084
866768003799	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
866768003800	ArsC family; Region: ArsC; pfam03960
866768003801	catalytic residues [active]
866768003802	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
866768003803	Peptidase family M48; Region: Peptidase_M48; cl12018
866768003804	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
866768003805	Domain of unknown function DUF20; Region: UPF0118; pfam01594
866768003806	putative formate transporter; Provisional; Region: focB; PRK09713
866768003807	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains [Transcription / Signal transduction mechanisms]; Region: FhlA; COG3604
866768003808	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
866768003809	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866768003810	Walker A motif; other site
866768003811	ATP binding site [chemical binding]; other site
866768003812	Walker B motif; other site
866768003813	arginine finger; other site
866768003814	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
866768003815	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
866768003816	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
866768003817	hydrogenase 4 subunit H; Validated; Region: PRK08222
866768003818	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
866768003819	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
866768003820	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
866768003821	NADH dehydrogenase subunit D; Validated; Region: PRK06075; cl17338
866768003822	hydrogenase 4 subunit F; Validated; Region: PRK06458
866768003823	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
866768003824	hydrogenase 4 membrane subunit; Provisional; Region: hyfE; PRK11492
866768003825	hydrogenase 4 subunit D; Validated; Region: PRK06525
866768003826	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
866768003827	hydrogenase 4 subunit D; Validated; Region: PRK06525
866768003828	hydrogenase 4 subunit B; Validated; Region: PRK06521
866768003829	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
866768003830	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
866768003831	4Fe-4S binding domain; Region: Fer4; pfam00037
866768003832	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
866768003833	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
866768003834	catalytic triad [active]
866768003835	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
866768003836	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
866768003837	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
866768003838	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
866768003839	dihydrodipicolinate synthase; Region: dapA; TIGR00674
866768003840	dimer interface [polypeptide binding]; other site
866768003841	active site
866768003842	catalytic residue [active]
866768003843	lipoprotein; Provisional; Region: PRK11679
866768003844	NlpB/DapX lipoprotein; Region: Lipoprotein_18; pfam06804
866768003845	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
866768003846	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
866768003847	ATP binding site [chemical binding]; other site
866768003848	active site
866768003849	substrate binding site [chemical binding]; other site
866768003850	Predicted metalloprotease [General function prediction only]; Region: COG2321
866768003851	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
866768003852	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
866768003853	Helicase; Region: Helicase_RecD; pfam05127
866768003854	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
866768003855	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
866768003856	putative hydrolase; Provisional; Region: PRK11460
866768003857	Phospholipase/Carboxylesterase; Region: Abhydrolase_2; pfam02230
866768003858	hypothetical protein; Provisional; Region: PRK13664
866768003859	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
866768003860	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
866768003861	metal binding site [ion binding]; metal-binding site
866768003862	dimer interface [polypeptide binding]; other site
866768003863	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
866768003864	ArsC family; Region: ArsC; pfam03960
866768003865	putative catalytic residues [active]
866768003866	aminoglycoside/multidrug efflux system; Provisional; Region: PRK10555
866768003867	Protein export membrane protein; Region: SecD_SecF; cl14618
866768003868	nitrate/nitrite sensor protein NarQ; Provisional; Region: PRK10935
866768003869	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
866768003870	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
866768003871	dimerization interface [polypeptide binding]; other site
866768003872	Histidine kinase; Region: HisKA_3; pfam07730
866768003873	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866768003874	ATP binding site [chemical binding]; other site
866768003875	Mg2+ binding site [ion binding]; other site
866768003876	G-X-G motif; other site
866768003877	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12769
866768003878	4Fe-4S binding domain; Region: Fer4; pfam00037
866768003879	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
866768003880	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
866768003881	GDP-mannose pyrophosphatase NudK; Provisional; Region: PRK15009
866768003882	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
866768003883	dimer interface [polypeptide binding]; other site
866768003884	ADP-ribose binding site [chemical binding]; other site
866768003885	active site
866768003886	nudix motif; other site
866768003887	metal binding site [ion binding]; metal-binding site
866768003888	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
866768003889	transketolase; Reviewed; Region: PRK12753
866768003890	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
866768003891	TPP-binding site [chemical binding]; other site
866768003892	dimer interface [polypeptide binding]; other site
866768003893	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
866768003894	PYR/PP interface [polypeptide binding]; other site
866768003895	dimer interface [polypeptide binding]; other site
866768003896	TPP binding site [chemical binding]; other site
866768003897	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
866768003898	transaldolase-like protein; Provisional; Region: PTZ00411
866768003899	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
866768003900	active site
866768003901	dimer interface [polypeptide binding]; other site
866768003902	catalytic residue [active]
866768003903	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
866768003904	Malic enzyme, N-terminal domain; Region: malic; pfam00390
866768003905	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
866768003906	putative NAD(P) binding site [chemical binding]; other site
866768003907	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
866768003908	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
866768003909	putative hexamer interface [polypeptide binding]; other site
866768003910	putative hexagonal pore; other site
866768003911	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
866768003912	G1 box; other site
866768003913	GTP/Mg2+ binding site [chemical binding]; other site
866768003914	G2 box; other site
866768003915	Switch I region; other site
866768003916	G3 box; other site
866768003917	Switch II region; other site
866768003918	G4 box; other site
866768003919	G5 box; other site
866768003920	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
866768003921	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutQ; COG4766
866768003922	ethanolamine utilization cobalamin adenosyltransferase; Provisional; Region: PRK15020
866768003923	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
866768003924	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
866768003925	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
866768003926	Hexamer interface [polypeptide binding]; other site
866768003927	Putative hexagonal pore residue; other site
866768003928	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
866768003929	Hexamer/Pentamer interface [polypeptide binding]; other site
866768003930	central pore; other site
866768003931	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
866768003932	putative catalytic cysteine [active]
866768003933	Ethanolamine utilization protein, possible chaperonin [Amino acid transport and metabolism]; Region: EutJ; COG4820
866768003934	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
866768003935	nucleotide binding site [chemical binding]; other site
866768003936	ethanol dehydrogenase EutG; Provisional; Region: PRK15454
866768003937	iron-containing alcohol dehydrogenases (Fe-ADH)-like; Region: Fe-ADH; cd08551
866768003938	active site
866768003939	metal binding site [ion binding]; metal-binding site
866768003940	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutH; COG3192
866768003941	reactivating factor for ethanolamine ammonia lyase; Provisional; Region: eutA; PRK10719
866768003942	Ethanolamine ammonia-lyase, large subunit [Amino acid transport and metabolism]; Region: EutB; COG4303
866768003943	Ethanolamine ammonia lyase large subunit (EutB); Region: EutB; pfam06751
866768003944	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
866768003945	ethanolamine utilization protein EutL; Provisional; Region: PRK15405
866768003946	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_EutL_repeat1; cd07049
866768003947	putative hexamer interface [polypeptide binding]; other site
866768003948	putative hexagonal pore; other site
866768003949	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_EutL_repeat2; cd07050
866768003950	putative hexamer interface [polypeptide binding]; other site
866768003951	putative hexagonal pore; other site
866768003952	carboxysome structural protein EutK; Provisional; Region: PRK15466
866768003953	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
866768003954	Hexamer interface [polypeptide binding]; other site
866768003955	Hexagonal pore residue; other site
866768003956	transcriptional regulator EutR; Provisional; Region: PRK10130
866768003957	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768003958	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768003959	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
866768003960	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
866768003961	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
866768003962	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
866768003963	active site
866768003964	metal binding site [ion binding]; metal-binding site
866768003965	putative acetyltransferase; Provisional; Region: PRK03624
866768003966	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
866768003967	Coenzyme A binding pocket [chemical binding]; other site
866768003968	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
866768003969	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
866768003970	Protein of unknown function (DUF1131); Region: DUF1131; pfam06572
866768003971	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
866768003972	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
866768003973	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
866768003974	active site turn [active]
866768003975	phosphorylation site [posttranslational modification]
866768003976	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
866768003977	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
866768003978	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
866768003979	putative active site [active]
866768003980	transcriptional regulator MurR; Provisional; Region: PRK15482
866768003981	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
866768003982	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
866768003983	putative active site [active]
866768003984	short chain dehydrogenase; Provisional; Region: PRK08226
866768003985	human DHRS6-like, classical (c) SDRs; Region: DHRS6_like_SDR_c; cd05368
866768003986	NAD binding site [chemical binding]; other site
866768003987	homotetramer interface [polypeptide binding]; other site
866768003988	homodimer interface [polypeptide binding]; other site
866768003989	active site
866768003990	thiosulfate transporter subunit; Provisional; Region: PRK10852
866768003991	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
866768003992	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
866768003993	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768003994	dimer interface [polypeptide binding]; other site
866768003995	conserved gate region; other site
866768003996	putative PBP binding loops; other site
866768003997	ABC-ATPase subunit interface; other site
866768003998	sulfate transport protein; Provisional; Region: cysT; CHL00187
866768003999	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768004000	dimer interface [polypeptide binding]; other site
866768004001	conserved gate region; other site
866768004002	putative PBP binding loops; other site
866768004003	ABC-ATPase subunit interface; other site
866768004004	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
866768004005	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
866768004006	Walker A/P-loop; other site
866768004007	ATP binding site [chemical binding]; other site
866768004008	Q-loop/lid; other site
866768004009	ABC transporter signature motif; other site
866768004010	Walker B; other site
866768004011	D-loop; other site
866768004012	H-loop/switch region; other site
866768004013	TOBE-like domain; Region: TOBE_3; pfam12857
866768004014	cysteine synthase B; Region: cysM; TIGR01138
866768004015	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
866768004016	dimer interface [polypeptide binding]; other site
866768004017	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768004018	catalytic residue [active]
866768004019	WGR domain of molybdate metabolism regulator and related proteins; Region: WGR_MMR_like; cd07996
866768004020	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4884
866768004021	hypothetical protein; Provisional; Region: PRK10318
866768004022	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
866768004023	dimer interface [polypeptide binding]; other site
866768004024	pyridoxamine kinase; Validated; Region: PRK05756
866768004025	pyridoxal binding site [chemical binding]; other site
866768004026	ATP binding site [chemical binding]; other site
866768004027	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
866768004028	HPr interaction site; other site
866768004029	glycerol kinase (GK) interaction site [polypeptide binding]; other site
866768004030	active site
866768004031	phosphorylation site [posttranslational modification]
866768004032	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
866768004033	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
866768004034	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
866768004035	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
866768004036	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
866768004037	dimerization domain swap beta strand [polypeptide binding]; other site
866768004038	regulatory protein interface [polypeptide binding]; other site
866768004039	active site
866768004040	regulatory phosphorylation site [posttranslational modification]; other site
866768004041	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
866768004042	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
866768004043	dimer interface [polypeptide binding]; other site
866768004044	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768004045	catalytic residue [active]
866768004046	putative sulfate transport protein CysZ; Validated; Region: PRK04949
866768004047	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cl12038
866768004048	cell division protein ZipA; Provisional; Region: PRK03427
866768004049	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
866768004050	FtsZ protein binding site [polypeptide binding]; other site
866768004051	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
866768004052	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
866768004053	nucleotide binding pocket [chemical binding]; other site
866768004054	K-X-D-G motif; other site
866768004055	catalytic site [active]
866768004056	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
866768004057	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
866768004058	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
866768004059	Dimer interface [polypeptide binding]; other site
866768004060	BRCT sequence motif; other site
866768004061	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3530
866768004062	Predicted Na+-dependent transporter [General function prediction only]; Region: COG0385
866768004063	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
866768004064	Transcriptional regulator [Transcription]; Region: LysR; COG0583
866768004065	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768004066	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
866768004067	putative dimerization interface [polypeptide binding]; other site
866768004068	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
866768004069	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
866768004070	active site
866768004071	HIGH motif; other site
866768004072	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
866768004073	active site
866768004074	KMSKS motif; other site
866768004075	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
866768004076	salt bridge; other site
866768004077	non-specific DNA binding site [nucleotide binding]; other site
866768004078	sequence-specific DNA binding site [nucleotide binding]; other site
866768004079	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
866768004080	MASE1; Region: MASE1; pfam05231
866768004081	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
866768004082	diguanylate cyclase; Region: GGDEF; smart00267
866768004083	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
866768004084	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
866768004085	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
866768004086	Nucleoside recognition; Region: Gate; pfam07670
866768004087	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
866768004088	manganese transport protein MntH; Reviewed; Region: PRK00701
866768004089	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
866768004090	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
866768004091	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
866768004092	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
866768004093	Cl- selectivity filter; other site
866768004094	Cl- binding residues [ion binding]; other site
866768004095	pore gating glutamate residue; other site
866768004096	dimer interface [polypeptide binding]; other site
866768004097	glucokinase, proteobacterial type; Region: glk; TIGR00749
866768004098	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
866768004099	nucleotide binding site [chemical binding]; other site
866768004100	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
866768004101	active site
866768004102	P-loop; other site
866768004103	phosphorylation site [posttranslational modification]
866768004104	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
866768004105	aminopeptidase; Provisional; Region: PRK09795
866768004106	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
866768004107	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
866768004108	active site
866768004109	exoaminopeptidase; Provisional; Region: PRK09961
866768004110	M42 Peptidases, also known as glutamyl aminopeptidase family; Region: M42; cd05638
866768004111	oligomer interface [polypeptide binding]; other site
866768004112	active site
866768004113	metal binding site [ion binding]; metal-binding site
866768004114	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
866768004115	dimerization domain swap beta strand [polypeptide binding]; other site
866768004116	regulatory protein interface [polypeptide binding]; other site
866768004117	active site
866768004118	regulatory phosphorylation site [posttranslational modification]; other site
866768004119	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
866768004120	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
866768004121	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
866768004122	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
866768004123	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
866768004124	active site
866768004125	phosphorylation site [posttranslational modification]
866768004126	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
866768004127	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768004128	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
866768004129	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768004130	active site
866768004131	phosphorylation site [posttranslational modification]
866768004132	intermolecular recognition site; other site
866768004133	dimerization interface [polypeptide binding]; other site
866768004134	LytTr DNA-binding domain; Region: LytTR; pfam04397
866768004135	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
866768004136	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
866768004137	GAF domain; Region: GAF; pfam01590
866768004138	Histidine kinase; Region: His_kinase; pfam06580
866768004139	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866768004140	ATP binding site [chemical binding]; other site
866768004141	Mg2+ binding site [ion binding]; other site
866768004142	G-X-G motif; other site
866768004143	aminotransferase; Validated; Region: PRK08175
866768004144	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
866768004145	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768004146	homodimer interface [polypeptide binding]; other site
866768004147	catalytic residue [active]
866768004148	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
866768004149	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
866768004150	putative acyl-acceptor binding pocket; other site
866768004151	Protein of unknown function (DUF2545); Region: DUF2545; pfam10810
866768004152	hypothetical protein; Provisional; Region: PRK10316
866768004153	YfdX protein; Region: YfdX; pfam10938
866768004154	formyl-coenzyme A transferase; Provisional; Region: PRK05398
866768004155	CoA-transferase family III; Region: CoA_transf_3; pfam02515
866768004156	putative oxalyl-CoA decarboxylase; Validated; Region: PRK09259
866768004157	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
866768004158	PYR/PP interface [polypeptide binding]; other site
866768004159	dimer interface [polypeptide binding]; other site
866768004160	TPP binding site [chemical binding]; other site
866768004161	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
866768004162	Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of proteins similar to benzaldehyde lyase (BZL), oxalyl-CoA decarboxylase (OCoD) and 2-hydroxyphytanoyl-CoA lyase (2-HPCL). Pseudomonas fluorescens biovar I BZL...; Region: TPP_BZL_OCoD_HPCL; cd02004
866768004163	TPP-binding site; other site
866768004164	dimer interface [polypeptide binding]; other site
866768004165	putative transporter YfdV; Provisional; Region: PRK09903
866768004166	putative CoA-transferase; Provisional; Region: PRK11430
866768004167	CoA-transferase family III; Region: CoA_transf_3; pfam02515
866768004168	hybrid sensory histidine kinase in two-component regulatory system with EvgA; Provisional; Region: PRK09959
866768004169	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
866768004170	substrate binding pocket [chemical binding]; other site
866768004171	membrane-bound complex binding site; other site
866768004172	hinge residues; other site
866768004173	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
866768004174	substrate binding pocket [chemical binding]; other site
866768004175	membrane-bound complex binding site; other site
866768004176	hinge residues; other site
866768004177	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
866768004178	dimer interface [polypeptide binding]; other site
866768004179	phosphorylation site [posttranslational modification]
866768004180	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866768004181	ATP binding site [chemical binding]; other site
866768004182	Mg2+ binding site [ion binding]; other site
866768004183	G-X-G motif; other site
866768004184	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768004185	active site
866768004186	phosphorylation site [posttranslational modification]
866768004187	intermolecular recognition site; other site
866768004188	dimerization interface [polypeptide binding]; other site
866768004189	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
866768004190	putative binding surface; other site
866768004191	active site
866768004192	DNA-binding transcriptional activator EvgA; Provisional; Region: PRK09958
866768004193	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768004194	active site
866768004195	phosphorylation site [posttranslational modification]
866768004196	intermolecular recognition site; other site
866768004197	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
866768004198	DNA binding residues [nucleotide binding]
866768004199	dimerization interface [polypeptide binding]; other site
866768004200	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
866768004201	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
866768004202	HlyD family secretion protein; Region: HlyD_3; pfam13437
866768004203	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
866768004204	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768004205	putative substrate translocation pore; other site
866768004206	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768004207	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
866768004208	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
866768004209	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
866768004210	catalytic residue [active]
866768004211	permease DsdX; Provisional; Region: PRK09921
866768004212	gluconate transporter; Region: gntP; TIGR00791
866768004213	DNA-binding transcriptional regulator DsdC; Provisional; Region: PRK10086
866768004214	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768004215	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
866768004216	dimerization interface [polypeptide binding]; other site
866768004217	substrate binding pocket [chemical binding]; other site
866768004218	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
866768004219	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
866768004220	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
866768004221	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
866768004222	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
866768004223	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
866768004224	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
866768004225	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3691
866768004226	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
866768004227	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
866768004228	dimer interface [polypeptide binding]; other site
866768004229	active site
866768004230	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
866768004231	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
866768004232	substrate binding site [chemical binding]; other site
866768004233	oxyanion hole (OAH) forming residues; other site
866768004234	trimer interface [polypeptide binding]; other site
866768004235	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
866768004236	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
866768004237	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
866768004238	catalytic core [active]
866768004239	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
866768004240	putative fimbrial outer membrane usher protein StfC; Provisional; Region: PRK15284
866768004241	PapC N-terminal domain; Region: PapC_N; pfam13954
866768004242	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
866768004243	PapC C-terminal domain; Region: PapC_C; pfam13953
866768004244	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
866768004245	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
866768004246	Fimbrial protein; Region: Fimbrial; cl01416
866768004247	Fimbrial protein; Region: Fimbrial; cl01416
866768004248	Fimbrial protein; Region: Fimbrial; cl01416
866768004249	Protein of unknown function (DUF2544); Region: DUF2544; pfam11245
866768004250	hypothetical protein; Provisional; Region: PRK04946
866768004251	Smr domain; Region: Smr; pfam01713
866768004252	HemK family putative methylases; Region: hemK_fam; TIGR00536
866768004253	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768004254	S-adenosylmethionine binding site [chemical binding]; other site
866768004255	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
866768004256	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
866768004257	Tetramer interface [polypeptide binding]; other site
866768004258	active site
866768004259	FMN-binding site [chemical binding]; other site
866768004260	Murein endopeptidase [Cell envelope biogenesis, outer membrane]; Region: MepA; COG3770
866768004261	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
866768004262	hypothetical protein; Provisional; Region: PRK10621
866768004263	Predicted permeases [General function prediction only]; Region: COG0730
866768004264	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3101
866768004265	YfcL protein; Region: YfcL; pfam08891
866768004266	Uncharacterized conserved protein [Function unknown]; Region: COG4121
866768004267	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
866768004268	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
866768004269	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
866768004270	dimer interface [polypeptide binding]; other site
866768004271	active site
866768004272	putative transporter; Provisional; Region: PRK12382
866768004273	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768004274	putative substrate translocation pore; other site
866768004275	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
866768004276	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
866768004277	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
866768004278	ligand binding site [chemical binding]; other site
866768004279	NAD binding site [chemical binding]; other site
866768004280	catalytic site [active]
866768004281	homodimer interface [polypeptide binding]; other site
866768004282	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
866768004283	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
866768004284	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
866768004285	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
866768004286	dimerization interface 3.5A [polypeptide binding]; other site
866768004287	active site
866768004288	hypothetical protein; Provisional; Region: PRK10847
866768004289	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
866768004290	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
866768004291	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
866768004292	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
866768004293	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
866768004294	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
866768004295	cell division protein DedD; Provisional; Region: PRK11633
866768004296	Sporulation related domain; Region: SPOR; pfam05036
866768004297	colicin V production protein; Provisional; Region: PRK10845
866768004298	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
866768004299	amidophosphoribosyltransferase; Provisional; Region: PRK09246
866768004300	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
866768004301	active site
866768004302	tetramer interface [polypeptide binding]; other site
866768004303	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
866768004304	active site
866768004305	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
866768004306	Flavoprotein; Region: Flavoprotein; pfam02441
866768004307	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
866768004308	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
866768004309	substrate binding pocket [chemical binding]; other site
866768004310	membrane-bound complex binding site; other site
866768004311	hinge residues; other site
866768004312	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
866768004313	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
866768004314	substrate binding pocket [chemical binding]; other site
866768004315	membrane-bound complex binding site; other site
866768004316	hinge residues; other site
866768004317	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
866768004318	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768004319	dimer interface [polypeptide binding]; other site
866768004320	conserved gate region; other site
866768004321	putative PBP binding loops; other site
866768004322	ABC-ATPase subunit interface; other site
866768004323	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768004324	dimer interface [polypeptide binding]; other site
866768004325	conserved gate region; other site
866768004326	putative PBP binding loops; other site
866768004327	ABC-ATPase subunit interface; other site
866768004328	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
866768004329	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
866768004330	Walker A/P-loop; other site
866768004331	ATP binding site [chemical binding]; other site
866768004332	Q-loop/lid; other site
866768004333	ABC transporter signature motif; other site
866768004334	Walker B; other site
866768004335	D-loop; other site
866768004336	H-loop/switch region; other site
866768004337	putative transposase; Provisional; Region: PRK09857
866768004338	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
866768004339	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
866768004340	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
866768004341	putative NAD(P) binding site [chemical binding]; other site
866768004342	putative active site [active]
866768004343	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
866768004344	homooctamer interface [polypeptide binding]; other site
866768004345	active site
866768004346	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
866768004347	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
866768004348	C-terminal domain interface [polypeptide binding]; other site
866768004349	GSH binding site (G-site) [chemical binding]; other site
866768004350	dimer interface [polypeptide binding]; other site
866768004351	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
866768004352	N-terminal domain interface [polypeptide binding]; other site
866768004353	putative dimer interface [polypeptide binding]; other site
866768004354	active site
866768004355	glutathione S-transferase; Provisional; Region: PRK15113
866768004356	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
866768004357	C-terminal domain interface [polypeptide binding]; other site
866768004358	GSH binding site (G-site) [chemical binding]; other site
866768004359	dimer interface [polypeptide binding]; other site
866768004360	C-terminal, alpha helical domain of an unknown subfamily 4 of Glutathione S-transferases; Region: GST_C_4; cd03195
866768004361	N-terminal domain interface [polypeptide binding]; other site
866768004362	putative dimer interface [polypeptide binding]; other site
866768004363	putative substrate binding pocket (H-site) [chemical binding]; other site
866768004364	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
866768004365	active site
866768004366	metal binding site [ion binding]; metal-binding site
866768004367	homotetramer interface [polypeptide binding]; other site
866768004368	NUDIX hydrolase YfcD; Provisional; Region: PRK15393
866768004369	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
866768004370	nudix motif; other site
866768004371	hypothetical protein; Provisional; Region: PRK11588
866768004372	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
866768004373	phosphate acetyltransferase; Reviewed; Region: PRK05632
866768004374	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
866768004375	DRTGG domain; Region: DRTGG; pfam07085
866768004376	phosphate acetyltransferase; Region: pta; TIGR00651
866768004377	propionate/acetate kinase; Provisional; Region: PRK12379
866768004378	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
866768004379	hypothetical protein; Provisional; Region: PRK01816
866768004380	hypothetical protein; Validated; Region: PRK05445
866768004381	putative phosphatase; Provisional; Region: PRK11587
866768004382	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866768004383	motif II; other site
866768004384	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
866768004385	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
866768004386	TrkA-C domain; Region: TrkA_C; pfam02080
866768004387	TrkA-C domain; Region: TrkA_C; pfam02080
866768004388	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
866768004389	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
866768004390	Zn2+ binding site [ion binding]; other site
866768004391	Mg2+ binding site [ion binding]; other site
866768004392	aminotransferase AlaT; Validated; Region: PRK09265
866768004393	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
866768004394	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768004395	homodimer interface [polypeptide binding]; other site
866768004396	catalytic residue [active]
866768004397	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
866768004398	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768004399	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
866768004400	putative dimerization interface [polypeptide binding]; other site
866768004401	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
866768004402	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
866768004403	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
866768004404	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
866768004405	NADH dehydrogenase subunit D; Validated; Region: PRK06075
866768004406	NADH dehydrogenase subunit E; Validated; Region: PRK07539
866768004407	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
866768004408	putative dimer interface [polypeptide binding]; other site
866768004409	[2Fe-2S] cluster binding site [ion binding]; other site
866768004410	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
866768004411	SLBB domain; Region: SLBB; pfam10531
866768004412	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
866768004413	NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) [Energy production and conversion]; Region: NuoG; COG1034
866768004414	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
866768004415	catalytic loop [active]
866768004416	iron binding site [ion binding]; other site
866768004417	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
866768004418	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
866768004419	[4Fe-4S] binding site [ion binding]; other site
866768004420	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
866768004421	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
866768004422	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
866768004423	4Fe-4S binding domain; Region: Fer4; pfam00037
866768004424	4Fe-4S binding domain; Region: Fer4; pfam00037
866768004425	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
866768004426	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
866768004427	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
866768004428	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
866768004429	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
866768004430	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
866768004431	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
866768004432	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
866768004433	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
866768004434	putative transposase OrfB; Reviewed; Region: PHA02517
866768004435	HTH-like domain; Region: HTH_21; pfam13276
866768004436	Integrase core domain; Region: rve; pfam00665
866768004437	Integrase core domain; Region: rve_2; pfam13333
866768004438	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
866768004439	Helix-turn-helix domain; Region: HTH_28; pfam13518
866768004440	Helix-turn-helix domain; Region: HTH_28; pfam13518
866768004441	Domain of unknown function (DUF1877); Region: DUF1877; pfam08974
866768004442	deubiquitinase; Provisional; Region: PRK11836
866768004443	ribonuclease BN; Region: true_RNase_BN; TIGR02649
866768004444	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
866768004445	Coenzyme A binding pocket [chemical binding]; other site
866768004446	hypothetical protein; Provisional; Region: PRK10404
866768004447	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
866768004448	isochorismate synthases; Region: isochor_syn; TIGR00543
866768004449	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
866768004450	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
866768004451	dimer interface [polypeptide binding]; other site
866768004452	tetramer interface [polypeptide binding]; other site
866768004453	PYR/PP interface [polypeptide binding]; other site
866768004454	TPP binding site [chemical binding]; other site
866768004455	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
866768004456	TPP-binding site; other site
866768004457	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
866768004458	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
866768004459	nucleophilic elbow; other site
866768004460	catalytic triad; other site
866768004461	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
866768004462	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
866768004463	substrate binding site [chemical binding]; other site
866768004464	oxyanion hole (OAH) forming residues; other site
866768004465	trimer interface [polypeptide binding]; other site
866768004466	O-succinylbenzoate synthase; Provisional; Region: PRK05105
866768004467	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
866768004468	active site
866768004469	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
866768004470	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
866768004471	acyl-activating enzyme (AAE) consensus motif; other site
866768004472	putative AMP binding site [chemical binding]; other site
866768004473	putative active site [active]
866768004474	putative CoA binding site [chemical binding]; other site
866768004475	signal transduction protein PmrD; Provisional; Region: PRK15450
866768004476	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
866768004477	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
866768004478	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
866768004479	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
866768004480	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
866768004481	Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939
866768004482	putative active site [active]
866768004483	putative catalytic site [active]
866768004484	putative Zn binding site [ion binding]; other site
866768004485	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
866768004486	ArnA, N-terminal formyltransferase domain; Region: FMT_core_ArnA_N; cd08644
866768004487	substrate binding site [chemical binding]; other site
866768004488	cosubstrate binding site; other site
866768004489	catalytic site [active]
866768004490	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
866768004491	active site
866768004492	hexamer interface [polypeptide binding]; other site
866768004493	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
866768004494	NAD binding site [chemical binding]; other site
866768004495	substrate binding site [chemical binding]; other site
866768004496	active site
866768004497	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
866768004498	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
866768004499	Ligand binding site; other site
866768004500	Putative Catalytic site; other site
866768004501	DXD motif; other site
866768004502	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
866768004503	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
866768004504	inhibitor-cofactor binding pocket; inhibition site
866768004505	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768004506	catalytic residue [active]
866768004507	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
866768004508	catalytic core [active]
866768004509	nucleoside triphosphatase NudI; Provisional; Region: PRK15472
866768004510	YfaZ precursor; Region: YfaZ; pfam07437
866768004511	outer membrane protein; Region: OMP_w_GlyGly; TIGR04219
866768004512	hypothetical protein; Provisional; Region: PRK03673
866768004513	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
866768004514	putative MPT binding site; other site
866768004515	Competence-damaged protein; Region: CinA; cl00666
866768004516	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
866768004517	Transcriptional regulator [Transcription]; Region: IclR; COG1414
866768004518	Bacterial transcriptional regulator; Region: IclR; pfam01614
866768004519	L-rhamnonate dehydratase; Provisional; Region: PRK15440
866768004520	Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 2. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic...; Region: MR_like_2; cd03327
866768004521	putative active site pocket [active]
866768004522	putative metal binding site [ion binding]; other site
866768004523	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
866768004524	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768004525	putative substrate translocation pore; other site
866768004526	2-keto-3-deoxy-L-rhamnonate aldolase; Provisional; Region: PRK10128
866768004527	hypothetical protein; Provisional; Region: PRK09956
866768004528	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
866768004529	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
866768004530	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
866768004531	Cysteine-rich domain; Region: CCG; pfam02754
866768004532	Cysteine-rich domain; Region: CCG; pfam02754
866768004533	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; COG3075
866768004534	anaerobic glycerol-3-phosphate dehydrogenase subunit B; Validated; Region: PRK05329
866768004535	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
866768004536	hydroxyglutarate oxidase; Provisional; Region: PRK11728
866768004537	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
866768004538	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
866768004539	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768004540	putative substrate translocation pore; other site
866768004541	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
866768004542	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
866768004543	active site
866768004544	catalytic site [active]
866768004545	metal binding site [ion binding]; metal-binding site
866768004546	hypothetical protein; Provisional; Region: PRK09729
866768004547	hypothetical protein; Provisional; Region: PRK09902
866768004548	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
866768004549	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
866768004550	catalytic loop [active]
866768004551	iron binding site [ion binding]; other site
866768004552	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
866768004553	dimer interface [polypeptide binding]; other site
866768004554	putative radical transfer pathway; other site
866768004555	diiron center [ion binding]; other site
866768004556	tyrosyl radical; other site
866768004557	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
866768004558	ATP cone domain; Region: ATP-cone; pfam03477
866768004559	Class I ribonucleotide reductase; Region: RNR_I; cd01679
866768004560	active site
866768004561	dimer interface [polypeptide binding]; other site
866768004562	catalytic residues [active]
866768004563	effector binding site; other site
866768004564	R2 peptide binding site; other site
866768004565	adhesin; Provisional; Region: PRK09752
866768004566	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
866768004567	Autotransporter beta-domain; Region: Autotransporter; pfam03797
866768004568	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
866768004569	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768004570	S-adenosylmethionine binding site [chemical binding]; other site
866768004571	DNA gyrase subunit A; Validated; Region: PRK05560
866768004572	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
866768004573	CAP-like domain; other site
866768004574	active site
866768004575	primary dimer interface [polypeptide binding]; other site
866768004576	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
866768004577	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
866768004578	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
866768004579	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
866768004580	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
866768004581	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
866768004582	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4685
866768004583	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3234
866768004584	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
866768004585	MG2 domain; Region: A2M_N; pfam01835
866768004586	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cl17457
866768004587	Alpha-2-macroglobulin family; Region: A2M; pfam00207
866768004588	This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate...; Region: ISOPREN_C2_like; cl08267
866768004589	Predicted secreted protein [Function unknown]; Region: COG5445
866768004590	Predicted secreted protein (DUF2300); Region: DUF2300; pfam10062
866768004591	Predicted secreted protein [Function unknown]; Region: COG5445
866768004592	Stage II sporulation protein; Region: SpoIID; pfam08486
866768004593	Predicted secreted protein (DUF2300); Region: DUF2300; pfam10062
866768004594	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4676
866768004595	Uncharacterized protein conserved in bacteria (DUF2135); Region: DUF2135; pfam09906
866768004596	putative acyltransferase; Provisional; Region: PRK05790
866768004597	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
866768004598	dimer interface [polypeptide binding]; other site
866768004599	active site
866768004600	Short chain fatty acid transporter; Region: SCFA_trans; pfam02667
866768004601	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
866768004602	acetyl-CoA:acetoacetyl-CoA transferase subunit alpha; Provisional; Region: PRK09920
866768004603	acetoacetate metabolism regulatory protein AtoC; Provisional; Region: PRK11361
866768004604	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768004605	active site
866768004606	phosphorylation site [posttranslational modification]
866768004607	intermolecular recognition site; other site
866768004608	dimerization interface [polypeptide binding]; other site
866768004609	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866768004610	Walker A motif; other site
866768004611	ATP binding site [chemical binding]; other site
866768004612	Walker B motif; other site
866768004613	arginine finger; other site
866768004614	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
866768004615	sensory histidine kinase AtoS; Provisional; Region: PRK11360
866768004616	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
866768004617	putative active site [active]
866768004618	heme pocket [chemical binding]; other site
866768004619	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
866768004620	dimer interface [polypeptide binding]; other site
866768004621	phosphorylation site [posttranslational modification]
866768004622	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866768004623	ATP binding site [chemical binding]; other site
866768004624	Mg2+ binding site [ion binding]; other site
866768004625	G-X-G motif; other site
866768004626	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
866768004627	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
866768004628	dimer interface [polypeptide binding]; other site
866768004629	phosphorylation site [posttranslational modification]
866768004630	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866768004631	ATP binding site [chemical binding]; other site
866768004632	Mg2+ binding site [ion binding]; other site
866768004633	G-X-G motif; other site
866768004634	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
866768004635	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768004636	active site
866768004637	phosphorylation site [posttranslational modification]
866768004638	intermolecular recognition site; other site
866768004639	dimerization interface [polypeptide binding]; other site
866768004640	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
866768004641	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
866768004642	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
866768004643	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
866768004644	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
866768004645	ApbE family; Region: ApbE; pfam02424
866768004646	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
866768004647	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
866768004648	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768004649	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768004650	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
866768004651	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
866768004652	DNA binding site [nucleotide binding]
866768004653	active site
866768004654	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
866768004655	multidrug transporter membrane component/ATP-binding component; Provisional; Region: PRK10522
866768004656	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
866768004657	Walker A/P-loop; other site
866768004658	ATP binding site [chemical binding]; other site
866768004659	Q-loop/lid; other site
866768004660	ABC transporter signature motif; other site
866768004661	Walker B; other site
866768004662	D-loop; other site
866768004663	H-loop/switch region; other site
866768004664	malate:quinone oxidoreductase; Validated; Region: PRK05257
866768004665	malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320
866768004666	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cd00242
866768004667	secondary substrate binding site; other site
866768004668	primary substrate binding site; other site
866768004669	inhibition loop; other site
866768004670	dimerization interface [polypeptide binding]; other site
866768004671	ferredoxin-type protein; Provisional; Region: PRK10194
866768004672	assembly protein for periplasmic nitrate reductase; Provisional; Region: PRK10553
866768004673	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
866768004674	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
866768004675	[4Fe-4S] binding site [ion binding]; other site
866768004676	molybdopterin cofactor binding site; other site
866768004677	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
866768004678	molybdopterin cofactor binding site; other site
866768004679	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
866768004680	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
866768004681	4Fe-4S binding domain; Region: Fer4_5; pfam12801
866768004682	4Fe-4S binding domain; Region: Fer4_6; pfam12837
866768004683	nitrate reductase cytochrome C550 subunit; Provisional; Region: napB; PRK11586
866768004684	cytochrome c-type protein NapC; Provisional; Region: PRK10617
866768004685	Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit [Energy production and conversion]; Region: TorC; COG3005
866768004686	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
866768004687	Cytochrome c biogenesis ATP-binding export protein; Region: ABC_CcmA_heme_exporter; cd03231
866768004688	Walker A/P-loop; other site
866768004689	ATP binding site [chemical binding]; other site
866768004690	Q-loop/lid; other site
866768004691	ABC transporter signature motif; other site
866768004692	Walker B; other site
866768004693	D-loop; other site
866768004694	H-loop/switch region; other site
866768004695	heme exporter protein CcmB; Region: ccmB; TIGR01190
866768004696	heme exporter protein CcmC; Region: ccmC; TIGR01191
866768004697	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
866768004698	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13165
866768004699	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
866768004700	thiol:disulfide interchange protein DsbE; Provisional; Region: PRK15412
866768004701	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
866768004702	catalytic residues [active]
866768004703	central insert; other site
866768004704	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
866768004705	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
866768004706	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
866768004707	binding surface
866768004708	TPR motif; other site
866768004709	transcriptional regulator NarP; Provisional; Region: PRK10403
866768004710	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768004711	active site
866768004712	phosphorylation site [posttranslational modification]
866768004713	intermolecular recognition site; other site
866768004714	dimerization interface [polypeptide binding]; other site
866768004715	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
866768004716	DNA binding residues [nucleotide binding]
866768004717	dimerization interface [polypeptide binding]; other site
866768004718	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
866768004719	hypothetical protein; Provisional; Region: PRK09945
866768004720	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
866768004721	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
866768004722	Autotransporter beta-domain; Region: Autotransporter; pfam03797
866768004723	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
866768004724	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
866768004725	Sulfatase; Region: Sulfatase; pfam00884
866768004726	hypothetical protein; Provisional; Region: PRK13689
866768004727	Nucleoid-associated protein [General function prediction only]; Region: COG3081
866768004728	nucleoid-associated protein NdpA; Validated; Region: PRK00378
866768004729	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
866768004730	5S rRNA interface [nucleotide binding]; other site
866768004731	CTC domain interface [polypeptide binding]; other site
866768004732	L16 interface [polypeptide binding]; other site
866768004733	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
866768004734	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
866768004735	ATP binding site [chemical binding]; other site
866768004736	putative Mg++ binding site [ion binding]; other site
866768004737	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
866768004738	nucleotide binding region [chemical binding]; other site
866768004739	ATP-binding site [chemical binding]; other site
866768004740	Ribosomal L40e family; Region: Ribosomal_L40e; cl00671
866768004741	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
866768004742	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
866768004743	RNA binding surface [nucleotide binding]; other site
866768004744	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
866768004745	active site
866768004746	uracil binding [chemical binding]; other site
866768004747	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768004748	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
866768004749	putative substrate translocation pore; other site
866768004750	hypothetical protein; Provisional; Region: PRK11835
866768004751	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
866768004752	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
866768004753	Walker A/P-loop; other site
866768004754	ATP binding site [chemical binding]; other site
866768004755	Q-loop/lid; other site
866768004756	ABC transporter signature motif; other site
866768004757	Walker B; other site
866768004758	D-loop; other site
866768004759	H-loop/switch region; other site
866768004760	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
866768004761	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
866768004762	Walker A/P-loop; other site
866768004763	ATP binding site [chemical binding]; other site
866768004764	Q-loop/lid; other site
866768004765	ABC transporter signature motif; other site
866768004766	Walker B; other site
866768004767	D-loop; other site
866768004768	H-loop/switch region; other site
866768004769	microcin C ABC transporter permease; Provisional; Region: PRK15021
866768004770	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768004771	dimer interface [polypeptide binding]; other site
866768004772	conserved gate region; other site
866768004773	ABC-ATPase subunit interface; other site
866768004774	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
866768004775	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768004776	dimer interface [polypeptide binding]; other site
866768004777	conserved gate region; other site
866768004778	putative PBP binding loops; other site
866768004779	ABC-ATPase subunit interface; other site
866768004780	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
866768004781	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
866768004782	phage resistance protein; Provisional; Region: PRK10551
866768004783	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
866768004784	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
866768004785	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
866768004786	NlpC/P60 family; Region: NLPC_P60; pfam00877
866768004787	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
866768004788	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
866768004789	active site
866768004790	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
866768004791	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
866768004792	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
866768004793	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
866768004794	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
866768004795	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
866768004796	elongation factor P; Provisional; Region: PRK04542
866768004797	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
866768004798	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
866768004799	RNA binding site [nucleotide binding]; other site
866768004800	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
866768004801	RNA binding site [nucleotide binding]; other site
866768004802	Flagellin N-methylase; Region: FliB; pfam03692
866768004803	sugar efflux transporter B; Provisional; Region: PRK15011
866768004804	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768004805	putative substrate translocation pore; other site
866768004806	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
866768004807	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
866768004808	active site
866768004809	phosphorylation site [posttranslational modification]
866768004810	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
866768004811	dimerization domain swap beta strand [polypeptide binding]; other site
866768004812	regulatory protein interface [polypeptide binding]; other site
866768004813	active site
866768004814	regulatory phosphorylation site [posttranslational modification]; other site
866768004815	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
866768004816	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
866768004817	putative substrate binding site [chemical binding]; other site
866768004818	putative ATP binding site [chemical binding]; other site
866768004819	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
866768004820	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
866768004821	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
866768004822	active site
866768004823	P-loop; other site
866768004824	phosphorylation site [posttranslational modification]
866768004825	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
866768004826	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
866768004827	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
866768004828	substrate binding site [chemical binding]; other site
866768004829	ATP binding site [chemical binding]; other site
866768004830	Indigoidine synthase A like protein; Region: Indigoidine_A; pfam04227
866768004831	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
866768004832	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
866768004833	Nucleoside recognition; Region: Gate; pfam07670
866768004834	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
866768004835	DNA-binding transcriptional activator YeiL; Provisional; Region: PRK10402
866768004836	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
866768004837	ligand binding site [chemical binding]; other site
866768004838	flexible hinge region; other site
866768004839	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
866768004840	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
866768004841	active site
866768004842	tetramer interface [polypeptide binding]; other site
866768004843	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
866768004844	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
866768004845	Nucleoside recognition; Region: Gate; pfam07670
866768004846	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
866768004847	putative kinase; Provisional; Region: PRK09954
866768004848	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
866768004849	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
866768004850	substrate binding site [chemical binding]; other site
866768004851	ATP binding site [chemical binding]; other site
866768004852	endonuclease IV; Provisional; Region: PRK01060
866768004853	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
866768004854	AP (apurinic/apyrimidinic) site pocket; other site
866768004855	DNA interaction; other site
866768004856	Metal-binding active site; metal-binding site
866768004857	conserved hypothetical integral membrane protein; Region: TIGR00698
866768004858	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
866768004859	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768004860	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
866768004861	putative dimerization interface [polypeptide binding]; other site
866768004862	lysine transporter; Provisional; Region: PRK10836
866768004863	catecholate siderophore receptor CirA; Provisional; Region: PRK10064
866768004864	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
866768004865	N-terminal plug; other site
866768004866	ligand-binding site [chemical binding]; other site
866768004867	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
866768004868	S-formylglutathione hydrolase; Region: PLN02442
866768004869	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
866768004870	homodecamer interface [polypeptide binding]; other site
866768004871	GTP cyclohydrolase I; Provisional; Region: PLN03044
866768004872	active site
866768004873	putative catalytic site residues [active]
866768004874	zinc binding site [ion binding]; other site
866768004875	GTP-CH-I/GFRP interaction surface; other site
866768004876	Predicted membrane protein [Function unknown]; Region: COG2311
866768004877	hypothetical protein; Provisional; Region: PRK10835
866768004878	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
866768004879	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
866768004880	DNA binding site [nucleotide binding]
866768004881	domain linker motif; other site
866768004882	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
866768004883	dimerization interface (closed form) [polypeptide binding]; other site
866768004884	ligand binding site [chemical binding]; other site
866768004885	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866768004886	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
866768004887	Walker A/P-loop; other site
866768004888	ATP binding site [chemical binding]; other site
866768004889	Q-loop/lid; other site
866768004890	ABC transporter signature motif; other site
866768004891	Walker B; other site
866768004892	D-loop; other site
866768004893	H-loop/switch region; other site
866768004894	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
866768004895	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
866768004896	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
866768004897	TM-ABC transporter signature motif; other site
866768004898	dihydropyrimidine dehydrogenase subunit B; Validated; Region: PRK08318
866768004899	Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain.  DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and...; Region: DHPD_FMN; cd02940
866768004900	homodimer interface [polypeptide binding]; other site
866768004901	active site
866768004902	FMN binding site [chemical binding]; other site
866768004903	substrate binding site [chemical binding]; other site
866768004904	4Fe-4S binding domain; Region: Fer4; pfam00037
866768004905	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
866768004906	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
866768004907	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
866768004908	Protein of unknown function (DUF2542); Region: DUF2542; pfam10808
866768004909	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
866768004910	putative active site [active]
866768004911	cytidine deaminase; Provisional; Region: PRK09027
866768004912	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
866768004913	active site
866768004914	catalytic motif [active]
866768004915	Zn binding site [ion binding]; other site
866768004916	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
866768004917	active site
866768004918	catalytic motif [active]
866768004919	Zn binding site [ion binding]; other site
866768004920	hypothetical protein; Provisional; Region: PRK10711
866768004921	hypothetical protein; Provisional; Region: PRK01821
866768004922	tRNA-dihydrouridine synthase C; Provisional; Region: PRK10550
866768004923	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
866768004924	FMN binding site [chemical binding]; other site
866768004925	active site
866768004926	catalytic residues [active]
866768004927	substrate binding site [chemical binding]; other site
866768004928	multidrug resistance outer membrane protein MdtQ; Provisional; Region: PRK11459
866768004929	oxidoreductase; Provisional; Region: PRK12743
866768004930	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
866768004931	NAD(P) binding site [chemical binding]; other site
866768004932	active site
866768004933	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
866768004934	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
866768004935	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
866768004936	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
866768004937	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
866768004938	D-lactate dehydrogenase; Provisional; Region: PRK11183
866768004939	FAD binding domain; Region: FAD_binding_4; pfam01565
866768004940	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
866768004941	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
866768004942	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
866768004943	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
866768004944	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
866768004945	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768004946	dimer interface [polypeptide binding]; other site
866768004947	conserved gate region; other site
866768004948	ABC-ATPase subunit interface; other site
866768004949	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
866768004950	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
866768004951	Walker A/P-loop; other site
866768004952	ATP binding site [chemical binding]; other site
866768004953	Q-loop/lid; other site
866768004954	ABC transporter signature motif; other site
866768004955	Walker B; other site
866768004956	D-loop; other site
866768004957	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
866768004958	H-loop/switch region; other site
866768004959	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
866768004960	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768004961	dimer interface [polypeptide binding]; other site
866768004962	conserved gate region; other site
866768004963	putative PBP binding loops; other site
866768004964	ABC-ATPase subunit interface; other site
866768004965	hypothetical protein; Provisional; Region: PRK13681
866768004966	transcriptional regulator MirA; Provisional; Region: PRK15043
866768004967	Helix-Turn-Helix DNA binding domain of MlrA-like transcription regulators; Region: HTH_MlrA-like; cd04763
866768004968	DNA binding residues [nucleotide binding]
866768004969	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
866768004970	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
866768004971	GAF domain; Region: GAF; pfam01590
866768004972	Histidine kinase; Region: His_kinase; pfam06580
866768004973	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866768004974	ATP binding site [chemical binding]; other site
866768004975	Mg2+ binding site [ion binding]; other site
866768004976	G-X-G motif; other site
866768004977	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
866768004978	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768004979	active site
866768004980	phosphorylation site [posttranslational modification]
866768004981	intermolecular recognition site; other site
866768004982	dimerization interface [polypeptide binding]; other site
866768004983	LytTr DNA-binding domain; Region: LytTR; pfam04397
866768004984	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
866768004985	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
866768004986	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
866768004987	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
866768004988	VWA domain containing CoxE-like protein; Region: VWA_CoxE; pfam05762
866768004989	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
866768004990	metal ion-dependent adhesion site (MIDAS); other site
866768004991	MoxR-like ATPases [General function prediction only]; Region: COG0714
866768004992	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866768004993	Walker A motif; other site
866768004994	ATP binding site [chemical binding]; other site
866768004995	Walker B motif; other site
866768004996	arginine finger; other site
866768004997	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
866768004998	WGR domain of molybdate metabolism regulator and related proteins; Region: WGR_MMR_like; cd07996
866768004999	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
866768005000	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
866768005001	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
866768005002	active site
866768005003	HIGH motif; other site
866768005004	KMSKS motif; other site
866768005005	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
866768005006	tRNA binding surface [nucleotide binding]; other site
866768005007	anticodon binding site; other site
866768005008	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
866768005009	dimer interface [polypeptide binding]; other site
866768005010	putative tRNA-binding site [nucleotide binding]; other site
866768005011	antiporter inner membrane protein; Provisional; Region: PRK11670
866768005012	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
866768005013	Walker A motif; other site
866768005014	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
866768005015	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
866768005016	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
866768005017	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
866768005018	Helix-turn-helix domain; Region: HTH_36; pfam13730
866768005019	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
866768005020	substrate binding site [chemical binding]; other site
866768005021	multimerization interface [polypeptide binding]; other site
866768005022	ATP binding site [chemical binding]; other site
866768005023	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
866768005024	dimer interface [polypeptide binding]; other site
866768005025	substrate binding site [chemical binding]; other site
866768005026	ATP binding site [chemical binding]; other site
866768005027	Lyzozyme M1 (1,4-beta-N-acetylmuramidase) [Cell envelope biogenesis, outer membrane]; Region: Acm; COG3757
866768005028	YegX is an uncharacterized bacterial protein with a glycosyl hydrolase family 25 (GH25) catalytic domain that is similar in sequence to the CH-type (Chalaropsis-type) lysozymes of the GH25 family of endolysins; Region: GH25_YegX-like; cd06524
866768005029	active site
866768005030	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
866768005031	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
866768005032	DNA-binding site [nucleotide binding]; DNA binding site
866768005033	UTRA domain; Region: UTRA; pfam07702
866768005034	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
866768005035	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
866768005036	substrate binding site [chemical binding]; other site
866768005037	ATP binding site [chemical binding]; other site
866768005038	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
866768005039	nucleoside transporter; Region: 2A0110; TIGR00889
866768005040	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768005041	putative substrate translocation pore; other site
866768005042	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
866768005043	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
866768005044	putative active site; other site
866768005045	catalytic residue [active]
866768005046	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
866768005047	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
866768005048	intersubunit interface [polypeptide binding]; other site
866768005049	active site
866768005050	zinc binding site [ion binding]; other site
866768005051	Na+ binding site [ion binding]; other site
866768005052	D-tagatose-1,6-bisphosphate aldolase subunit GatZ; Provisional; Region: PRK15052
866768005053	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
866768005054	active site
866768005055	phosphorylation site [posttranslational modification]
866768005056	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
866768005057	active site
866768005058	P-loop; other site
866768005059	phosphorylation site [posttranslational modification]
866768005060	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
866768005061	PTS system, galactitol-specific IIC component; Region: EIIC-GAT; TIGR00827
866768005062	galactitol-1-phosphate dehydrogenase; Provisional; Region: PRK10309
866768005063	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
866768005064	putative NAD(P) binding site [chemical binding]; other site
866768005065	catalytic Zn binding site [ion binding]; other site
866768005066	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
866768005067	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
866768005068	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
866768005069	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
866768005070	lipid kinase; Reviewed; Region: PRK13054
866768005071	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
866768005072	putative protease; Provisional; Region: PRK15452
866768005073	Peptidase family U32; Region: Peptidase_U32; pfam01136
866768005074	Uncharacterized conserved protein [Function unknown]; Region: COG3422
866768005075	Domain of unknown function (DUF1508); Region: DUF1508; pfam07411
866768005076	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
866768005077	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768005078	active site
866768005079	phosphorylation site [posttranslational modification]
866768005080	intermolecular recognition site; other site
866768005081	dimerization interface [polypeptide binding]; other site
866768005082	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
866768005083	DNA binding site [nucleotide binding]
866768005084	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
866768005085	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
866768005086	dimerization interface [polypeptide binding]; other site
866768005087	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
866768005088	dimer interface [polypeptide binding]; other site
866768005089	phosphorylation site [posttranslational modification]
866768005090	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866768005091	ATP binding site [chemical binding]; other site
866768005092	Mg2+ binding site [ion binding]; other site
866768005093	G-X-G motif; other site
866768005094	putative transporter; Provisional; Region: PRK10504
866768005095	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768005096	putative substrate translocation pore; other site
866768005097	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768005098	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
866768005099	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
866768005100	Protein export membrane protein; Region: SecD_SecF; cl14618
866768005101	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
866768005102	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
866768005103	HlyD family secretion protein; Region: HlyD_3; pfam13437
866768005104	VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subfamily; cd01464
866768005105	metal ion-dependent adhesion site (MIDAS); other site
866768005106	Protein phosphatase 2C; Region: PP2C_2; pfam13672
866768005107	Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains [General function prediction only]; Region: COG4248
866768005108	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
866768005109	substrate binding site [chemical binding]; other site
866768005110	activation loop (A-loop); other site
866768005111	Y-family of DNA polymerases; Region: PolY; cl12025
866768005112	putative chaperone; Provisional; Region: PRK11678
866768005113	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
866768005114	nucleotide binding site [chemical binding]; other site
866768005115	putative NEF/HSP70 interaction site [polypeptide binding]; other site
866768005116	SBD interface [polypeptide binding]; other site
866768005117	3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308
866768005118	AlkA N-terminal domain; Region: AlkA_N; smart01009
866768005119	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
866768005120	minor groove reading motif; other site
866768005121	helix-hairpin-helix signature motif; other site
866768005122	substrate binding pocket [chemical binding]; other site
866768005123	active site
866768005124	Predicted integral membrane sensor domain [Signal transduction mechanisms]; Region: COG3447
866768005125	putative diguanylate cyclase; Provisional; Region: PRK09776
866768005126	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
866768005127	putative active site [active]
866768005128	heme pocket [chemical binding]; other site
866768005129	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
866768005130	putative active site [active]
866768005131	heme pocket [chemical binding]; other site
866768005132	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
866768005133	putative active site [active]
866768005134	heme pocket [chemical binding]; other site
866768005135	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
866768005136	metal binding site [ion binding]; metal-binding site
866768005137	active site
866768005138	I-site; other site
866768005139	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
866768005140	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
866768005141	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
866768005142	ATP-binding site [chemical binding]; other site
866768005143	Sugar specificity; other site
866768005144	Pyrimidine base specificity; other site
866768005145	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
866768005146	trimer interface [polypeptide binding]; other site
866768005147	active site
866768005148	putative assembly protein; Provisional; Region: PRK10833
866768005149	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
866768005150	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
866768005151	FOG: CBS domain [General function prediction only]; Region: COG0517
866768005152	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
866768005153	Transporter associated domain; Region: CorC_HlyC; smart01091
866768005154	polysaccharide export protein Wza; Provisional; Region: PRK15078
866768005155	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
866768005156	SLBB domain; Region: SLBB; pfam10531
866768005157	Low molecular weight phosphatase family; Region: LMWPc; cd00115
866768005158	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
866768005159	active site
866768005160	tyrosine kinase; Provisional; Region: PRK11519
866768005161	Chain length determinant protein; Region: Wzz; pfam02706
866768005162	Chain length determinant protein; Region: Wzz; cl15801
866768005163	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
866768005164	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
866768005165	putative glycosyl transferase; Provisional; Region: PRK10018
866768005166	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
866768005167	active site
866768005168	putative acyl transferase; Provisional; Region: PRK10191
866768005169	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
866768005170	trimer interface [polypeptide binding]; other site
866768005171	active site
866768005172	substrate binding site [chemical binding]; other site
866768005173	CoA binding site [chemical binding]; other site
866768005174	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
866768005175	colanic acid biosynthesis glycosyl transferase WcaC; Region: WcaC; TIGR04015
866768005176	putative colanic acid polymerase WcaD; Region: WcaD; TIGR04010
866768005177	putative glycosyl transferase; Provisional; Region: PRK10063
866768005178	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
866768005179	metal-binding site
866768005180	colanic acid biosynthesis acetyltransferase WcaF; Region: WcaF; TIGR04008
866768005181	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
866768005182	putative trimer interface [polypeptide binding]; other site
866768005183	putative active site [active]
866768005184	putative substrate binding site [chemical binding]; other site
866768005185	putative CoA binding site [chemical binding]; other site
866768005186	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
866768005187	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
866768005188	NADP-binding site; other site
866768005189	homotetramer interface [polypeptide binding]; other site
866768005190	substrate binding site [chemical binding]; other site
866768005191	homodimer interface [polypeptide binding]; other site
866768005192	active site
866768005193	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
866768005194	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
866768005195	NADP binding site [chemical binding]; other site
866768005196	active site
866768005197	putative substrate binding site [chemical binding]; other site
866768005198	GDP-mannose glycosyl hydrolase (AKA GDP-mannose mannosyl hydrolase (GDPMH)) is a member of the Nudix hydrolase superfamily. This class of enzymes is unique from other members of the superfamily in two aspects. First, it contains a modified Nudix...; Region: GDPMH; cd03430
866768005199	active site
866768005200	GDP-Mannose binding site [chemical binding]; other site
866768005201	dimer interface [polypeptide binding]; other site
866768005202	modified nudix motif
866768005203	metal binding site [ion binding]; metal-binding site
866768005204	colanic acid biosynthesis glycosyl transferase WcaI; Region: wcaI; TIGR04007
866768005205	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
866768005206	mannose-1-phosphate guanyltransferase; Provisional; Region: cpsB; PRK15460
866768005207	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
866768005208	Substrate binding site; other site
866768005209	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
866768005210	phosphomannomutase CpsG; Provisional; Region: PRK15414
866768005211	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
866768005212	active site
866768005213	substrate binding site [chemical binding]; other site
866768005214	metal binding site [ion binding]; metal-binding site
866768005215	putative UDP-glucose lipid carrier transferase; Provisional; Region: PRK10124
866768005216	Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane]; Region: WcaJ; COG2148
866768005217	colanic acid exporter; Provisional; Region: PRK10459
866768005218	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
866768005219	Polysaccharide pyruvyl transferase family protein [Cell wall/membrane/envelope biogenesis]; Region: WcaK; COG2327
866768005220	colanic acid biosynthesis pyruvyl transferase WcaK; Region: wcaK; TIGR04006
866768005221	colanic acid biosynthesis glycosyltransferase WcaL; Region: wcaL; TIGR04005
866768005222	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
866768005223	putative ADP-binding pocket [chemical binding]; other site
866768005224	putative colanic acid biosynthesis protein; Provisional; Region: wcaM; PRK10123
866768005225	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
866768005226	active site
866768005227	tetramer interface; other site
866768005228	dTDP-glucose 4,6 dehydratase; Provisional; Region: PRK10084
866768005229	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
866768005230	NAD binding site [chemical binding]; other site
866768005231	substrate binding site [chemical binding]; other site
866768005232	homodimer interface [polypeptide binding]; other site
866768005233	active site
866768005234	dTDP-4-dehydrorhamnose reductase; Provisional; Region: PRK09987
866768005235	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
866768005236	NADP binding site [chemical binding]; other site
866768005237	active site
866768005238	putative substrate binding site [chemical binding]; other site
866768005239	glucose-1-phosphate thymidylyltransferase RfbA; Provisional; Region: PRK15480
866768005240	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
866768005241	substrate binding site; other site
866768005242	tetramer interface; other site
866768005243	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
866768005244	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
866768005245	colanic acid exporter; Provisional; Region: PRK10459
866768005246	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
866768005247	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
866768005248	inhibitor-cofactor binding pocket; inhibition site
866768005249	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768005250	catalytic residue [active]
866768005251	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
866768005252	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
866768005253	trimer interface [polypeptide binding]; other site
866768005254	active site
866768005255	substrate binding site [chemical binding]; other site
866768005256	CoA binding site [chemical binding]; other site
866768005257	ornithine decarboxylase SpeF; Region: ODC_inducible; TIGR04301
866768005258	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
866768005259	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
866768005260	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
866768005261	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
866768005262	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
866768005263	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
866768005264	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479
866768005265	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
866768005266	Substrate binding site; other site
866768005267	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
866768005268	phosphomannomutase CpsG; Provisional; Region: PRK15414
866768005269	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
866768005270	active site
866768005271	substrate binding site [chemical binding]; other site
866768005272	metal binding site [ion binding]; metal-binding site
866768005273	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
866768005274	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
866768005275	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
866768005276	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
866768005277	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
866768005278	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
866768005279	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
866768005280	chain length determinant protein WzzB; Provisional; Region: PRK15471
866768005281	Chain length determinant protein; Region: Wzz; pfam02706
866768005282	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
866768005283	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
866768005284	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
866768005285	metal binding site [ion binding]; metal-binding site
866768005286	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
866768005287	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
866768005288	substrate binding site [chemical binding]; other site
866768005289	glutamase interaction surface [polypeptide binding]; other site
866768005290	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
866768005291	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
866768005292	catalytic residues [active]
866768005293	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
866768005294	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
866768005295	putative active site [active]
866768005296	oxyanion strand; other site
866768005297	catalytic triad [active]
866768005298	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
866768005299	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866768005300	active site
866768005301	motif I; other site
866768005302	motif II; other site
866768005303	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
866768005304	putative active site pocket [active]
866768005305	4-fold oligomerization interface [polypeptide binding]; other site
866768005306	metal binding residues [ion binding]; metal-binding site
866768005307	3-fold/trimer interface [polypeptide binding]; other site
866768005308	histidinol-phosphate aminotransferase; Provisional; Region: PRK01688
866768005309	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
866768005310	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768005311	homodimer interface [polypeptide binding]; other site
866768005312	catalytic residue [active]
866768005313	Histidinol dehydrogenase; Region: Histidinol_dh; pfam00815
866768005314	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
866768005315	NAD binding site [chemical binding]; other site
866768005316	dimerization interface [polypeptide binding]; other site
866768005317	product binding site; other site
866768005318	substrate binding site [chemical binding]; other site
866768005319	zinc binding site [ion binding]; other site
866768005320	catalytic residues [active]
866768005321	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
866768005322	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
866768005323	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
866768005324	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
866768005325	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
866768005326	putative NAD(P) binding site [chemical binding]; other site
866768005327	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768005328	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
866768005329	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
866768005330	dimerization interface [polypeptide binding]; other site
866768005331	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
866768005332	putative selenium metabolism protein, YedE family; Region: seleno_YedE; TIGR04112
866768005333	Sulphur transport; Region: Sulf_transp; pfam04143
866768005334	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291
866768005335	CPxP  motif; other site
866768005336	exonuclease I; Provisional; Region: sbcB; PRK11779
866768005337	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
866768005338	active site
866768005339	catalytic site [active]
866768005340	substrate binding site [chemical binding]; other site
866768005341	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
866768005342	D-alanyl-D-alanine carboxypeptidase; Provisional; Region: dacD; PRK11397
866768005343	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
866768005344	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
866768005345	DNA gyrase inhibitor; Provisional; Region: PRK10016
866768005346	Predicted membrane protein [Function unknown]; Region: COG1289
866768005347	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
866768005348	hypothetical protein; Provisional; Region: PRK05423
866768005349	Protein of unknown function (DUF3279); Region: DUF3279; pfam11682
866768005350	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
866768005351	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
866768005352	homotrimer interface [polypeptide binding]; other site
866768005353	Walker A motif; other site
866768005354	GTP binding site [chemical binding]; other site
866768005355	Walker B motif; other site
866768005356	cobalamin 5'-phosphate synthase/cobalamin synthase; Region: cobS; TIGR00317
866768005357	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
866768005358	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
866768005359	putative dimer interface [polypeptide binding]; other site
866768005360	active site pocket [active]
866768005361	putative cataytic base [active]
866768005362	L,D-transpeptidase; Provisional; Region: PRK10190
866768005363	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
866768005364	nitrogen assimilation transcriptional regulator; Provisional; Region: PRK11233
866768005365	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768005366	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
866768005367	putative dimerization interface [polypeptide binding]; other site
866768005368	transcriptional regulator Cbl; Reviewed; Region: cbl; PRK12679
866768005369	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768005370	The C-terminal substrate binding domain of LysR-type transcriptional regulator Cbl, which is required for expression of sulfate starvation-inducible (ssi) genes, contains the type 2 periplasmic binding fold; Region: PBP2_Cbl; cd08444
866768005371	putative substrate binding site [chemical binding]; other site
866768005372	dimerization interface [polypeptide binding]; other site
866768005373	MATE family multidrug exporter; Provisional; Region: PRK10189
866768005374	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
866768005375	hypothetical protein; Provisional; Region: PRK12378
866768005376	AMP nucleosidase; Provisional; Region: PRK08292
866768005377	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
866768005378	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
866768005379	shikimate transporter; Provisional; Region: PRK09952
866768005380	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768005381	putative substrate translocation pore; other site
866768005382	putative invasin; Provisional; Region: PRK10177
866768005383	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
866768005384	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
866768005385	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
866768005386	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
866768005387	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
866768005388	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
866768005389	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
866768005390	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
866768005391	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
866768005392	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
866768005393	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
866768005394	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
866768005395	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
866768005396	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
866768005397	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
866768005398	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
866768005399	zinc/cadmium-binding protein; Provisional; Region: PRK10306
866768005400	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
866768005401	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
866768005402	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
866768005403	TMAO/DMSO reductase; Reviewed; Region: PRK05363
866768005404	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
866768005405	Moco binding site; other site
866768005406	metal coordination site [ion binding]; other site
866768005407	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
866768005408	active site
866768005409	homotetramer interface [polypeptide binding]; other site
866768005410	transcriptional regulatory protein YedW; Provisional; Region: PRK11517
866768005411	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768005412	active site
866768005413	phosphorylation site [posttranslational modification]
866768005414	intermolecular recognition site; other site
866768005415	dimerization interface [polypeptide binding]; other site
866768005416	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
866768005417	DNA binding site [nucleotide binding]
866768005418	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
866768005419	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
866768005420	dimer interface [polypeptide binding]; other site
866768005421	phosphorylation site [posttranslational modification]
866768005422	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866768005423	ATP binding site [chemical binding]; other site
866768005424	Mg2+ binding site [ion binding]; other site
866768005425	G-X-G motif; other site
866768005426	chaperone protein HchA; Provisional; Region: PRK04155
866768005427	Type 1 glutamine amidotransferase (GATase1)-like domain found in Escherichia coli Hsp31 protein (EcHsp31); Region: GATase1_EcHsp31_like; cd03148
866768005428	dimer interface [polypeptide binding]; other site
866768005429	metal binding site [ion binding]; metal-binding site
866768005430	potential oxyanion hole; other site
866768005431	potential catalytic triad [active]
866768005432	conserved cys residue [active]
866768005433	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
866768005434	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
866768005435	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
866768005436	Zn2+ binding site [ion binding]; other site
866768005437	Mg2+ binding site [ion binding]; other site
866768005438	DNA cytosine methylase; Provisional; Region: PRK10458
866768005439	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
866768005440	cofactor binding site; other site
866768005441	DNA binding site [nucleotide binding]
866768005442	substrate interaction site [chemical binding]; other site
866768005443	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
866768005444	additional DNA contacts [nucleotide binding]; other site
866768005445	mismatch recognition site; other site
866768005446	active site
866768005447	zinc binding site [ion binding]; other site
866768005448	DNA intercalation site [nucleotide binding]; other site
866768005449	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
866768005450	EamA-like transporter family; Region: EamA; pfam00892
866768005451	hypothetical protein; Provisional; Region: PRK10062
866768005452	Uncharacterized small protein [Function unknown]; Region: COG5475
866768005453	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
866768005454	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
866768005455	metal binding site [ion binding]; metal-binding site
866768005456	active site
866768005457	I-site; other site
866768005458	mannosyl-3-phosphoglycerate phosphatase; Reviewed; Region: PRK03669
866768005459	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866768005460	active site
866768005461	motif I; other site
866768005462	motif II; other site
866768005463	Protein of unknown function (DUF2525); Region: DUF2525; pfam10733
866768005464	hypothetical protein; Provisional; Region: PRK10708
866768005465	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
866768005466	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
866768005467	DNA binding residues [nucleotide binding]
866768005468	dimerization interface [polypeptide binding]; other site
866768005469	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
866768005470	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
866768005471	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
866768005472	flagellar biosynthesis protein FliO; Provisional; Region: PRK11486
866768005473	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
866768005474	flagellar motor switch protein; Validated; Region: fliN; PRK05698
866768005475	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
866768005476	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
866768005477	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
866768005478	Flagellar hook-length control protein [Cell motility and secretion]; Region: FliK; COG3144
866768005479	flagellar hook-length control protein; Provisional; Region: PRK10118
866768005480	Flagellar biosynthesis chaperone [Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FliJ; COG2882
866768005481	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
866768005482	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
866768005483	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
866768005484	Walker A motif/ATP binding site; other site
866768005485	Walker B motif; other site
866768005486	flagellar assembly protein H; Validated; Region: fliH; PRK05687
866768005487	Essential protein Yae1, N terminal; Region: Yae1_N; pfam09811
866768005488	Flagellar assembly protein FliH; Region: FliH; pfam02108
866768005489	flagellar motor switch protein FliG; Region: fliG; TIGR00207
866768005490	FliG C-terminal domain; Region: FliG_C; pfam01706
866768005491	flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF); Region: fliF; TIGR00206
866768005492	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
866768005493	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
866768005494	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK00253
866768005495	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
866768005496	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
866768005497	Coenzyme A binding pocket [chemical binding]; other site
866768005498	hypothetical protein; Provisional; Region: PRK09951
866768005499	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
866768005500	CPxP  motif; other site
866768005501	putative inner membrane protein; Provisional; Region: PRK11099
866768005502	lipoprotein; Provisional; Region: PRK10397
866768005503	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
866768005504	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
866768005505	active site
866768005506	Na/Ca binding site [ion binding]; other site
866768005507	catalytic site [active]
866768005508	flagellar biosynthesis protein FliT; Provisional; Region: PRK10548
866768005509	flagellar biosynthetic protein FliS; Region: fliS; TIGR00208
866768005510	flagellar capping protein; Reviewed; Region: fliD; PRK08032
866768005511	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
866768005512	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
866768005513	flagellin; Validated; Region: PRK08026
866768005514	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
866768005515	Flagellin D3 domain; Region: Flagellin_D3; pfam08884
866768005516	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
866768005517	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
866768005518	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
866768005519	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
866768005520	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
866768005521	DNA binding residues [nucleotide binding]
866768005522	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
866768005523	cystine transporter subunit; Provisional; Region: PRK11260
866768005524	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
866768005525	substrate binding pocket [chemical binding]; other site
866768005526	membrane-bound complex binding site; other site
866768005527	hinge residues; other site
866768005528	D-cysteine desulfhydrase; Validated; Region: PRK03910
866768005529	Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449
866768005530	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768005531	catalytic residue [active]
866768005532	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
866768005533	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768005534	dimer interface [polypeptide binding]; other site
866768005535	conserved gate region; other site
866768005536	putative PBP binding loops; other site
866768005537	ABC-ATPase subunit interface; other site
866768005538	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
866768005539	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
866768005540	Walker A/P-loop; other site
866768005541	ATP binding site [chemical binding]; other site
866768005542	Q-loop/lid; other site
866768005543	ABC transporter signature motif; other site
866768005544	Walker B; other site
866768005545	D-loop; other site
866768005546	H-loop/switch region; other site
866768005547	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
866768005548	Autoinducer binding domain; Region: Autoind_bind; pfam03472
866768005549	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
866768005550	DNA binding residues [nucleotide binding]
866768005551	dimerization interface [polypeptide binding]; other site
866768005552	hypothetical protein; Provisional; Region: PRK10613
866768005553	response regulator; Provisional; Region: PRK09483
866768005554	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768005555	active site
866768005556	phosphorylation site [posttranslational modification]
866768005557	intermolecular recognition site; other site
866768005558	dimerization interface [polypeptide binding]; other site
866768005559	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
866768005560	DNA binding residues [nucleotide binding]
866768005561	dimerization interface [polypeptide binding]; other site
866768005562	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
866768005563	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
866768005564	GIY-YIG motif/motif A; other site
866768005565	active site
866768005566	catalytic site [active]
866768005567	putative DNA binding site [nucleotide binding]; other site
866768005568	metal binding site [ion binding]; metal-binding site
866768005569	UvrB/uvrC motif; Region: UVR; pfam02151
866768005570	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
866768005571	Helix-hairpin-helix motif; Region: HHH; pfam00633
866768005572	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
866768005573	hypothetical protein; Provisional; Region: PRK10396
866768005574	yecA family protein; Region: ygfB_yecA; TIGR02292
866768005575	SEC-C motif; Region: SEC-C; pfam02810
866768005576	tyrosine transporter TyrP; Provisional; Region: PRK15132
866768005577	aromatic amino acid transport protein; Region: araaP; TIGR00837
866768005578	probable metal-binding protein; Region: matur_matur; TIGR03853
866768005579	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
866768005580	Ferritin-like domain; Region: Ferritin; pfam00210
866768005581	ferroxidase diiron center [ion binding]; other site
866768005582	YecR-like lipoprotein; Region: YecR; pfam13992
866768005583	Protein of unknown function (DUF2766); Region: DUF2766; pfam10964
866768005584	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
866768005585	Ferritin-like domain; Region: Ferritin; pfam00210
866768005586	ferroxidase diiron center [ion binding]; other site
866768005587	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
866768005588	Periplasmic L-arabinose-binding protein (ABP), a member of a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein superfamily; Region: PBP1_arabinose_binding; cd01540
866768005589	ligand binding site [chemical binding]; other site
866768005590	L-arabinose transporter ATP-binding protein; Provisional; Region: araG; PRK11288
866768005591	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
866768005592	Walker A/P-loop; other site
866768005593	ATP binding site [chemical binding]; other site
866768005594	Q-loop/lid; other site
866768005595	ABC transporter signature motif; other site
866768005596	Walker B; other site
866768005597	D-loop; other site
866768005598	H-loop/switch region; other site
866768005599	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
866768005600	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
866768005601	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
866768005602	TM-ABC transporter signature motif; other site
866768005603	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187
866768005604	Trehalose-6-phosphatase [Carbohydrate transport and metabolism]; Region: OtsB; COG1877
866768005605	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
866768005606	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
866768005607	active site
866768005608	homotetramer interface [polypeptide binding]; other site
866768005609	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
866768005610	Ligand Binding Site [chemical binding]; other site
866768005611	transcriptional activator FlhD; Provisional; Region: PRK02909
866768005612	transcriptional activator FlhC; Provisional; Region: PRK12722
866768005613	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
866768005614	flagellar motor protein MotA; Validated; Region: PRK09110
866768005615	flagellar motor protein MotB; Validated; Region: motB; PRK09041
866768005616	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
866768005617	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
866768005618	ligand binding site [chemical binding]; other site
866768005619	chemotaxis protein CheA; Provisional; Region: PRK10547
866768005620	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
866768005621	putative binding surface; other site
866768005622	active site
866768005623	CheY binding; Region: CheY-binding; pfam09078
866768005624	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
866768005625	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866768005626	ATP binding site [chemical binding]; other site
866768005627	Mg2+ binding site [ion binding]; other site
866768005628	G-X-G motif; other site
866768005629	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
866768005630	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
866768005631	putative CheA interaction surface; other site
866768005632	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
866768005633	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
866768005634	dimer interface [polypeptide binding]; other site
866768005635	ligand binding site [chemical binding]; other site
866768005636	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
866768005637	dimerization interface [polypeptide binding]; other site
866768005638	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
866768005639	dimer interface [polypeptide binding]; other site
866768005640	putative CheW interface [polypeptide binding]; other site
866768005641	methyl-accepting protein IV; Provisional; Region: PRK09793
866768005642	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
866768005643	dimer interface [polypeptide binding]; other site
866768005644	ligand binding site [chemical binding]; other site
866768005645	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
866768005646	dimerization interface [polypeptide binding]; other site
866768005647	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
866768005648	dimer interface [polypeptide binding]; other site
866768005649	putative CheW interface [polypeptide binding]; other site
866768005650	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
866768005651	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
866768005652	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768005653	S-adenosylmethionine binding site [chemical binding]; other site
866768005654	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
866768005655	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768005656	active site
866768005657	phosphorylation site [posttranslational modification]
866768005658	intermolecular recognition site; other site
866768005659	dimerization interface [polypeptide binding]; other site
866768005660	CheB methylesterase; Region: CheB_methylest; pfam01339
866768005661	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
866768005662	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768005663	active site
866768005664	phosphorylation site [posttranslational modification]
866768005665	intermolecular recognition site; other site
866768005666	dimerization interface [polypeptide binding]; other site
866768005667	chemotaxis regulator CheZ; Provisional; Region: PRK11166
866768005668	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
866768005669	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
866768005670	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
866768005671	FHIPEP family; Region: FHIPEP; pfam00771
866768005672	Flagellar protein FlhE; Region: FlhE; pfam06366
866768005673	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3755
866768005674	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
866768005675	arginyl-tRNA synthetase; Region: argS; TIGR00456
866768005676	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
866768005677	active site
866768005678	HIGH motif; other site
866768005679	KMSK motif region; other site
866768005680	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
866768005681	tRNA binding surface [nucleotide binding]; other site
866768005682	anticodon binding site; other site
866768005683	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
866768005684	putative metal binding site [ion binding]; other site
866768005685	copper homeostasis protein CutC; Provisional; Region: PRK11572
866768005686	trimethylamine-N-oxide reductase c-type cytochrome TorC; Region: torC; TIGR02162
866768005687	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
866768005688	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
866768005689	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
866768005690	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
866768005691	molybdopterin cofactor binding site [chemical binding]; other site
866768005692	substrate binding site [chemical binding]; other site
866768005693	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
866768005694	molybdopterin cofactor binding site; other site
866768005695	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768005696	S-adenosylmethionine binding site [chemical binding]; other site
866768005697	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768005698	S-adenosylmethionine binding site [chemical binding]; other site
866768005699	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
866768005700	hypothetical protein; Provisional; Region: PRK10302
866768005701	Isochorismatase family; Region: Isochorismatase; pfam00857
866768005702	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
866768005703	catalytic triad [active]
866768005704	conserved cis-peptide bond; other site
866768005705	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
866768005706	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
866768005707	dimer interface [polypeptide binding]; other site
866768005708	anticodon binding site; other site
866768005709	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
866768005710	homodimer interface [polypeptide binding]; other site
866768005711	motif 1; other site
866768005712	active site
866768005713	motif 2; other site
866768005714	GAD domain; Region: GAD; pfam02938
866768005715	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
866768005716	motif 3; other site
866768005717	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
866768005718	nudix motif; other site
866768005719	hypothetical protein; Validated; Region: PRK00110
866768005720	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
866768005721	active site
866768005722	putative DNA-binding cleft [nucleotide binding]; other site
866768005723	dimer interface [polypeptide binding]; other site
866768005724	hypothetical protein; Provisional; Region: PRK11470
866768005725	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
866768005726	RuvA N terminal domain; Region: RuvA_N; pfam01330
866768005727	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
866768005728	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
866768005729	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866768005730	Walker A motif; other site
866768005731	ATP binding site [chemical binding]; other site
866768005732	Walker B motif; other site
866768005733	arginine finger; other site
866768005734	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
866768005735	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
866768005736	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
866768005737	ABC-ATPase subunit  interface; other site
866768005738	dimer interface [polypeptide binding]; other site
866768005739	putative PBP binding regions; other site
866768005740	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
866768005741	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
866768005742	high-affinity zinc transporter periplasmic component; Reviewed; Region: znuA; PRK09545
866768005743	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
866768005744	metal binding site [ion binding]; metal-binding site
866768005745	putative peptidase; Provisional; Region: PRK11649
866768005746	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
866768005747	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
866768005748	Peptidase family M23; Region: Peptidase_M23; pfam01551
866768005749	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
866768005750	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
866768005751	putative acyl-acceptor binding pocket; other site
866768005752	pyruvate kinase; Provisional; Region: PRK05826
866768005753	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
866768005754	domain interfaces; other site
866768005755	active site
866768005756	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
866768005757	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
866768005758	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
866768005759	putative active site [active]
866768005760	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
866768005761	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
866768005762	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
866768005763	phosphogluconate dehydratase; Validated; Region: PRK09054
866768005764	6-phosphogluconate dehydratase; Region: edd; TIGR01196
866768005765	keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase; Provisional; Region: PRK05718
866768005766	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
866768005767	active site
866768005768	intersubunit interface [polypeptide binding]; other site
866768005769	catalytic residue [active]
866768005770	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
866768005771	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
866768005772	ATP-grasp domain; Region: ATP-grasp; pfam02222
866768005773	DNA damage-inducible protein YebG; Provisional; Region: PRK10061
866768005774	hypothetical protein; Provisional; Region: PRK13680
866768005775	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2979
866768005776	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
866768005777	putative metal binding site [ion binding]; other site
866768005778	protease 2; Provisional; Region: PRK10115
866768005779	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
866768005780	exodeoxyribonuclease X; Provisional; Region: PRK07983
866768005781	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
866768005782	active site
866768005783	catalytic site [active]
866768005784	substrate binding site [chemical binding]; other site
866768005785	Predicted amidohydrolase [General function prediction only]; Region: COG0388
866768005786	Carbon-nitrogen hydrolase; Region: CN_hydrolase; pfam00795
866768005787	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
866768005788	hypothetical protein; Provisional; Region: PRK10301
866768005789	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
866768005790	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
866768005791	serine/threonine protein phosphatase 1; Provisional; Region: pphA; PRK11439
866768005792	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
866768005793	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
866768005794	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
866768005795	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
866768005796	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768005797	S-adenosylmethionine binding site [chemical binding]; other site
866768005798	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
866768005799	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
866768005800	mce related protein; Region: MCE; pfam02470
866768005801	mce related protein; Region: MCE; pfam02470
866768005802	mce related protein; Region: MCE; pfam02470
866768005803	mce related protein; Region: MCE; pfam02470
866768005804	mce related protein; Region: MCE; pfam02470
866768005805	integral membrane protein, PqiA family; Region: pqiA_fam; TIGR00155
866768005806	Paraquat-inducible protein A; Region: PqiA; pfam04403
866768005807	Paraquat-inducible protein A; Region: PqiA; pfam04403
866768005808	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
866768005809	GAF domain; Region: GAF_2; pfam13185
866768005810	ProP expression regulator; Provisional; Region: PRK04950
866768005811	ProQ/FINO family; Region: ProQ; pfam04352
866768005812	carboxy-terminal protease; Provisional; Region: PRK11186
866768005813	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
866768005814	protein binding site [polypeptide binding]; other site
866768005815	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
866768005816	Catalytic dyad [active]
866768005817	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
866768005818	heat shock protein HtpX; Provisional; Region: PRK05457
866768005819	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768005820	Major Facilitator Superfamily; Region: MFS_1; pfam07690
866768005821	putative substrate translocation pore; other site
866768005822	Predicted integral membrane protein [Function unknown]; Region: COG5521
866768005823	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
866768005824	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
866768005825	dimerization interface [polypeptide binding]; other site
866768005826	putative Zn2+ binding site [ion binding]; other site
866768005827	putative DNA binding site [nucleotide binding]; other site
866768005828	Bacterial transcriptional regulator; Region: IclR; pfam01614
866768005829	YobH-like protein; Region: YobH; pfam13996
866768005830	PhoPQ regulatory protein; Provisional; Region: PRK10299
866768005831	YebO-like protein; Region: YebO; pfam13974
866768005832	Protein of unknown function (DUF2627); Region: DUF2527; pfam10736
866768005833	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
866768005834	DNA-binding site [nucleotide binding]; DNA binding site
866768005835	RNA-binding motif; other site
866768005836	23S rRNA methyltransferase A; Provisional; Region: rrmA; PRK11088
866768005837	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768005838	S-adenosylmethionine binding site [chemical binding]; other site
866768005839	hypothetical protein; Provisional; Region: PRK11469
866768005840	Domain of unknown function DUF; Region: DUF204; pfam02659
866768005841	Domain of unknown function DUF; Region: DUF204; pfam02659
866768005842	Predicted membrane protein [Function unknown]; Region: COG4811
866768005843	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
866768005844	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
866768005845	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
866768005846	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
866768005847	active pocket/dimerization site; other site
866768005848	active site
866768005849	phosphorylation site [posttranslational modification]
866768005850	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
866768005851	active site
866768005852	phosphorylation site [posttranslational modification]
866768005853	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
866768005854	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
866768005855	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
866768005856	Transporter associated domain; Region: CorC_HlyC; smart01091
866768005857	phage resistance protein; Provisional; Region: PRK10551
866768005858	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
866768005859	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
866768005860	L-serine deaminase; Provisional; Region: PRK15023
866768005861	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
866768005862	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
866768005863	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
866768005864	putative active site [active]
866768005865	putative CoA binding site [chemical binding]; other site
866768005866	nudix motif; other site
866768005867	metal binding site [ion binding]; metal-binding site
866768005868	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
866768005869	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
866768005870	aminodeoxychorismate synthase, component I, bacterial clade; Region: pabB; TIGR00553
866768005871	hypothetical protein; Provisional; Region: PRK05114
866768005872	Domain of unknown function (DUF1889); Region: DUF1889; pfam08986
866768005873	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
866768005874	homotrimer interaction site [polypeptide binding]; other site
866768005875	putative active site [active]
866768005876	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
866768005877	DEAD/DEAH box helicase; Region: DEAD; pfam00270
866768005878	DEAD_2; Region: DEAD_2; pfam06733
866768005879	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
866768005880	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
866768005881	Glycoprotease family; Region: Peptidase_M22; pfam00814
866768005882	Outer membrane lipoprotein Slp family; Region: Slp; cl01164
866768005883	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
866768005884	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
866768005885	acyl-activating enzyme (AAE) consensus motif; other site
866768005886	putative AMP binding site [chemical binding]; other site
866768005887	putative active site [active]
866768005888	putative CoA binding site [chemical binding]; other site
866768005889	ribonuclease D; Provisional; Region: PRK10829
866768005890	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
866768005891	catalytic site [active]
866768005892	putative active site [active]
866768005893	putative substrate binding site [chemical binding]; other site
866768005894	Helicase and RNase D C-terminal; Region: HRDC; smart00341
866768005895	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018
866768005896	Phthalate dioxygenase reductase (PDR) is an FMN-dependent reductase that mediates electron transfer from NADH to FMN to an iron sulfur cluster. PDR has an an N-terminal  ferrredoxin reductase (FNR)-like NAD(H) binding domain and a C-terminal iron-sulfur; Region: PDR_like; cd06185
866768005897	FMN-binding pocket [chemical binding]; other site
866768005898	flavin binding motif; other site
866768005899	phosphate binding motif [ion binding]; other site
866768005900	beta-alpha-beta structure motif; other site
866768005901	NAD binding pocket [chemical binding]; other site
866768005902	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
866768005903	catalytic loop [active]
866768005904	iron binding site [ion binding]; other site
866768005905	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
866768005906	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
866768005907	[2Fe-2S] cluster binding site [ion binding]; other site
866768005908	C-terminal catalytic domain of the oxygenase alpha subunit of an uncharacterized subgroup of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases; Region: RHO_alpha_C_2; cd08886
866768005909	putative alpha subunit interface [polypeptide binding]; other site
866768005910	putative active site [active]
866768005911	putative substrate binding site [chemical binding]; other site
866768005912	Fe binding site [ion binding]; other site
866768005913	Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473
866768005914	tartrate dehydrogenase; Region: TTC; TIGR02089
866768005915	transcriptional activator TtdR; Provisional; Region: PRK09801
866768005916	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768005917	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
866768005918	putative effector binding pocket; other site
866768005919	putative dimerization interface [polypeptide binding]; other site
866768005920	leucine export protein LeuE; Provisional; Region: PRK10958
866768005921	Domain of unknown function (DUF1971); Region: DUF1971; cl17717
866768005922	Domain of unknown function (DUF1869); Region: DUF1869; pfam08956
866768005923	hypothetical protein; Provisional; Region: PRK10457
866768005924	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
866768005925	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
866768005926	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
866768005927	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
866768005928	metal binding site [ion binding]; metal-binding site
866768005929	active site
866768005930	I-site; other site
866768005931	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
866768005932	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
866768005933	Domain of unknown function (DUF333); Region: DUF333; pfam03891
866768005934	Uncharacterized conserved protein [Function unknown]; Region: COG3189
866768005935	cyanate transporter; Region: CynX; TIGR00896
866768005936	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768005937	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
866768005938	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768005939	Predicted membrane protein [Function unknown]; Region: COG2707
866768005940	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
866768005941	putative deacylase active site [active]
866768005942	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
866768005943	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
866768005944	metal binding site [ion binding]; metal-binding site
866768005945	active site
866768005946	I-site; other site
866768005947	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
866768005948	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
866768005949	metal binding site [ion binding]; metal-binding site
866768005950	active site
866768005951	I-site; other site
866768005952	hypothetical protein; Provisional; Region: PRK05325
866768005953	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
866768005954	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
866768005955	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
866768005956	active site
866768005957	catalytic tetrad [active]
866768005958	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
866768005959	active site
866768005960	phosphate binding residues; other site
866768005961	catalytic residues [active]
866768005962	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
866768005963	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
866768005964	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
866768005965	methionine sulfoxide reductase B; Provisional; Region: PRK00222
866768005966	SelR domain; Region: SelR; pfam01641
866768005967	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3139
866768005968	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
866768005969	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH4; cd08258
866768005970	putative NAD(P) binding site [chemical binding]; other site
866768005971	catalytic Zn binding site [ion binding]; other site
866768005972	structural Zn binding site [ion binding]; other site
866768005973	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768005974	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768005975	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
866768005976	Sorbitol dehydrogenase; Region: sorbitol_DH; cd05285
866768005977	inhibitor binding site; inhibition site
866768005978	catalytic Zn binding site [ion binding]; other site
866768005979	structural Zn binding site [ion binding]; other site
866768005980	NADP binding site [chemical binding]; other site
866768005981	tetramer interface [polypeptide binding]; other site
866768005982	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
866768005983	intersubunit interface [polypeptide binding]; other site
866768005984	active site
866768005985	zinc binding site [ion binding]; other site
866768005986	Na+ binding site [ion binding]; other site
866768005987	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
866768005988	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
866768005989	substrate binding site [chemical binding]; other site
866768005990	ATP binding site [chemical binding]; other site
866768005991	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
866768005992	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
866768005993	active site
866768005994	catalytic tetrad [active]
866768005995	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
866768005996	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
866768005997	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
866768005998	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
866768005999	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768006000	putative substrate translocation pore; other site
866768006001	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768006002	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
866768006003	Isochorismatase family; Region: Isochorismatase; pfam00857
866768006004	catalytic triad [active]
866768006005	metal binding site [ion binding]; metal-binding site
866768006006	conserved cis-peptide bond; other site
866768006007	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
866768006008	active site
866768006009	homodimer interface [polypeptide binding]; other site
866768006010	protease 4; Provisional; Region: PRK10949
866768006011	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
866768006012	tandem repeat interface [polypeptide binding]; other site
866768006013	oligomer interface [polypeptide binding]; other site
866768006014	active site residues [active]
866768006015	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019
866768006016	tandem repeat interface [polypeptide binding]; other site
866768006017	oligomer interface [polypeptide binding]; other site
866768006018	active site residues [active]
866768006019	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
866768006020	putative FMN binding site [chemical binding]; other site
866768006021	selenophosphate synthetase; Provisional; Region: PRK00943
866768006022	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
866768006023	dimerization interface [polypeptide binding]; other site
866768006024	putative ATP binding site [chemical binding]; other site
866768006025	DNA topoisomerase III; Provisional; Region: PRK07726
866768006026	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
866768006027	active site
866768006028	putative interdomain interaction site [polypeptide binding]; other site
866768006029	putative metal-binding site [ion binding]; other site
866768006030	putative nucleotide binding site [chemical binding]; other site
866768006031	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
866768006032	domain I; other site
866768006033	DNA binding groove [nucleotide binding]
866768006034	phosphate binding site [ion binding]; other site
866768006035	domain II; other site
866768006036	domain III; other site
866768006037	nucleotide binding site [chemical binding]; other site
866768006038	catalytic site [active]
866768006039	domain IV; other site
866768006040	hypothetical protein; Provisional; Region: PRK11380
866768006041	glutamate dehydrogenase; Provisional; Region: PRK09414
866768006042	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
866768006043	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
866768006044	NAD(P) binding site [chemical binding]; other site
866768006045	Protein of unknown function (DUF1496); Region: DUF1496; pfam07383
866768006046	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
866768006047	active site
866768006048	8-oxo-dGMP binding site [chemical binding]; other site
866768006049	nudix motif; other site
866768006050	metal binding site [ion binding]; metal-binding site
866768006051	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
866768006052	Rhodanese Homology Domain; Region: RHOD; smart00450
866768006053	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
866768006054	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
866768006055	active site residue [active]
866768006056	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
866768006057	active site residue [active]
866768006058	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4136
866768006059	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866768006060	Walker A/P-loop; other site
866768006061	ATP binding site [chemical binding]; other site
866768006062	Q-loop/lid; other site
866768006063	ABC transporter signature motif; other site
866768006064	Walker B; other site
866768006065	D-loop; other site
866768006066	H-loop/switch region; other site
866768006067	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4135
866768006068	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768006069	dimer interface [polypeptide binding]; other site
866768006070	conserved gate region; other site
866768006071	putative PBP binding loops; other site
866768006072	ABC-ATPase subunit interface; other site
866768006073	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4134
866768006074	hypothetical protein; Provisional; Region: PRK11622
866768006075	Uncharacterized conserved protein [Function unknown]; Region: COG2128
866768006076	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
866768006077	Uncharacterized conserved protein [Function unknown]; Region: COG0398
866768006078	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
866768006079	Uncharacterized conserved protein [Function unknown]; Region: COG0398
866768006080	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
866768006081	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
866768006082	putative catalytic site [active]
866768006083	putative phosphate binding site [ion binding]; other site
866768006084	active site
866768006085	metal binding site A [ion binding]; metal-binding site
866768006086	DNA binding site [nucleotide binding]
866768006087	putative AP binding site [nucleotide binding]; other site
866768006088	putative metal binding site B [ion binding]; other site
866768006089	bifunctional succinylornithine transaminase/acetylornithine transaminase; Provisional; Region: PRK12381
866768006090	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
866768006091	inhibitor-cofactor binding pocket; inhibition site
866768006092	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768006093	catalytic residue [active]
866768006094	arginine succinyltransferase; Provisional; Region: PRK10456
866768006095	Arginine/ornithine N-succinyltransferase beta subunit [Amino acid transport and metabolism]; Region: AstA; COG3138
866768006096	succinylglutamic semialdehyde dehydrogenase; Reviewed; Region: astD; PRK09457
866768006097	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
866768006098	NAD(P) binding site [chemical binding]; other site
866768006099	catalytic residues [active]
866768006100	succinylarginine dihydrolase; Provisional; Region: PRK13281
866768006101	Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855
866768006102	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
866768006103	putative active site [active]
866768006104	Zn binding site [ion binding]; other site
866768006105	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
866768006106	dimer interface [polypeptide binding]; other site
866768006107	hypothetical protein; Provisional; Region: PRK11396
866768006108	nucleotide excision repair endonuclease; Provisional; Region: PRK10545
866768006109	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
866768006110	GIY-YIG motif/motif A; other site
866768006111	active site
866768006112	catalytic site [active]
866768006113	putative DNA binding site [nucleotide binding]; other site
866768006114	metal binding site [ion binding]; metal-binding site
866768006115	NAD+ synthetase; Region: nadE; TIGR00552
866768006116	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
866768006117	homodimer interface [polypeptide binding]; other site
866768006118	NAD binding pocket [chemical binding]; other site
866768006119	ATP binding pocket [chemical binding]; other site
866768006120	Mg binding site [ion binding]; other site
866768006121	active-site loop [active]
866768006122	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
866768006123	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
866768006124	active site
866768006125	P-loop; other site
866768006126	phosphorylation site [posttranslational modification]
866768006127	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
866768006128	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
866768006129	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
866768006130	methionine cluster; other site
866768006131	active site
866768006132	phosphorylation site [posttranslational modification]
866768006133	metal binding site [ion binding]; metal-binding site
866768006134	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
866768006135	Cupin domain; Region: Cupin_2; pfam07883
866768006136	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768006137	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
866768006138	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
866768006139	NAD binding site [chemical binding]; other site
866768006140	sugar binding site [chemical binding]; other site
866768006141	divalent metal binding site [ion binding]; other site
866768006142	tetramer (dimer of dimers) interface [polypeptide binding]; other site
866768006143	dimer interface [polypeptide binding]; other site
866768006144	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
866768006145	putative active site [active]
866768006146	YdjC motif; other site
866768006147	Mg binding site [ion binding]; other site
866768006148	putative homodimer interface [polypeptide binding]; other site
866768006149	hydroperoxidase II; Provisional; Region: katE; PRK11249
866768006150	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
866768006151	tetramer interface [polypeptide binding]; other site
866768006152	heme binding pocket [chemical binding]; other site
866768006153	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
866768006154	domain interactions; other site
866768006155	cell division modulator; Provisional; Region: PRK10113
866768006156	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
866768006157	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
866768006158	inner membrane protein; Provisional; Region: PRK11648
866768006159	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
866768006160	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
866768006161	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866768006162	motif II; other site
866768006163	YniB-like protein; Region: YniB; pfam14002
866768006164	Phosphotransferase enzyme family; Region: APH; pfam01636
866768006165	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
866768006166	active site
866768006167	ATP binding site [chemical binding]; other site
866768006168	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
866768006169	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
866768006170	6-phosphofructokinase 2; Provisional; Region: PRK10294
866768006171	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
866768006172	putative substrate binding site [chemical binding]; other site
866768006173	putative ATP binding site [chemical binding]; other site
866768006174	Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG3137
866768006175	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
866768006176	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
866768006177	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
866768006178	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
866768006179	active site
866768006180	dimer interface [polypeptide binding]; other site
866768006181	motif 1; other site
866768006182	motif 2; other site
866768006183	motif 3; other site
866768006184	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
866768006185	anticodon binding site; other site
866768006186	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
866768006187	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
866768006188	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
866768006189	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
866768006190	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
866768006191	23S rRNA binding site [nucleotide binding]; other site
866768006192	L21 binding site [polypeptide binding]; other site
866768006193	L13 binding site [polypeptide binding]; other site
866768006194	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
866768006195	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
866768006196	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
866768006197	dimer interface [polypeptide binding]; other site
866768006198	motif 1; other site
866768006199	active site
866768006200	motif 2; other site
866768006201	motif 3; other site
866768006202	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
866768006203	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
866768006204	putative tRNA-binding site [nucleotide binding]; other site
866768006205	B3/4 domain; Region: B3_4; pfam03483
866768006206	tRNA synthetase B5 domain; Region: B5; smart00874
866768006207	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
866768006208	dimer interface [polypeptide binding]; other site
866768006209	motif 1; other site
866768006210	motif 3; other site
866768006211	motif 2; other site
866768006212	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
866768006213	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
866768006214	IHF dimer interface [polypeptide binding]; other site
866768006215	IHF - DNA interface [nucleotide binding]; other site
866768006216	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
866768006217	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
866768006218	ABC-ATPase subunit  interface; other site
866768006219	dimer interface [polypeptide binding]; other site
866768006220	putative PBP binding regions; other site
866768006221	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
866768006222	catalytic residues [active]
866768006223	dimer interface [polypeptide binding]; other site
866768006224	vitamin B12-transporter ATPase; Provisional; Region: PRK03695
866768006225	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
866768006226	Walker A/P-loop; other site
866768006227	ATP binding site [chemical binding]; other site
866768006228	Q-loop/lid; other site
866768006229	ABC transporter signature motif; other site
866768006230	Walker B; other site
866768006231	D-loop; other site
866768006232	H-loop/switch region; other site
866768006233	NlpC/P60 family; Region: NLPC_P60; pfam00877
866768006234	Uncharacterized conserved protein [Function unknown]; Region: COG0397
866768006235	hypothetical protein; Validated; Region: PRK00029
866768006236	Hemin uptake protein [Inorganic ion transport and metabolism]; Region: HemP; COG4256
866768006237	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
866768006238	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
866768006239	PEP synthetase regulatory protein; Provisional; Region: PRK05339
866768006240	phosphoenolpyruvate synthase; Validated; Region: PRK06464
866768006241	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
866768006242	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
866768006243	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
866768006244	short chain acyl-CoA synthetase; Reviewed; Region: PRK06087
866768006245	Cyclohexanecarboxylate-CoA ligase (also called cyclohex-1-ene-1-carboxylate:CoA ligase); Region: CHC_CoA_lg; cd05903
866768006246	acyl-activating enzyme (AAE) consensus motif; other site
866768006247	putative AMP binding site [chemical binding]; other site
866768006248	putative active site [active]
866768006249	putative CoA binding site [chemical binding]; other site
866768006250	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
866768006251	oxidoreductase; Provisional; Region: PRK10015
866768006252	electron transfer flavoprotein subunit YdiR; Provisional; Region: PRK11916
866768006253	Electron transfer flavoprotein domain; Region: ETF; smart00893
866768006254	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
866768006255	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
866768006256	Ligand binding site [chemical binding]; other site
866768006257	Electron transfer flavoprotein domain; Region: ETF; pfam01012
866768006258	Cupin domain; Region: Cupin_2; pfam07883
866768006259	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
866768006260	putative acyl-CoA dehydrogenase; Provisional; Region: PRK12341
866768006261	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
866768006262	active site
866768006263	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
866768006264	Coenzyme A transferase; Region: CoA_trans; smart00882
866768006265	Coenzyme A transferase; Region: CoA_trans; cl17247
866768006266	3-dehydroquinate dehydratase [Amino acid transport and metabolism]; Region: AroD; COG0710
866768006267	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
866768006268	active site
866768006269	catalytic residue [active]
866768006270	dimer interface [polypeptide binding]; other site
866768006271	quinate/shikimate dehydrogenase; Reviewed; Region: PRK12749
866768006272	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
866768006273	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
866768006274	shikimate binding site; other site
866768006275	NAD(P) binding site [chemical binding]; other site
866768006276	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768006277	putative substrate translocation pore; other site
866768006278	Domain of unknown function (DUF1870); Region: DUF1870; pfam08965
866768006279	putative inner membrane protein; Provisional; Region: PRK10983
866768006280	Domain of unknown function DUF20; Region: UPF0118; pfam01594
866768006281	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
866768006282	FAD binding domain; Region: FAD_binding_4; pfam01565
866768006283	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
866768006284	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
866768006285	CoenzymeA binding site [chemical binding]; other site
866768006286	subunit interaction site [polypeptide binding]; other site
866768006287	PHB binding site; other site
866768006288	Iron-sulphur cluster biosynthesis; Region: Fe-S_biosyn; cl00400
866768006289	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814; cl03223
866768006290	Uncharacterized protein family (UPF0051); Region: UPF0051; pfam01458
866768006291	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
866768006292	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
866768006293	Walker A/P-loop; other site
866768006294	ATP binding site [chemical binding]; other site
866768006295	Q-loop/lid; other site
866768006296	ABC transporter signature motif; other site
866768006297	Walker B; other site
866768006298	D-loop; other site
866768006299	H-loop/switch region; other site
866768006300	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
866768006301	FeS assembly protein SufD; Region: sufD; TIGR01981
866768006302	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
866768006303	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
866768006304	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
866768006305	catalytic residue [active]
866768006306	cysteine desufuration protein SufE; Provisional; Region: PRK09296
866768006307	L,D-transpeptidase; Provisional; Region: PRK10190
866768006308	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
866768006309	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
866768006310	murein lipoprotein; Provisional; Region: PRK15396
866768006311	pyruvate kinase; Provisional; Region: PRK09206
866768006312	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
866768006313	domain interfaces; other site
866768006314	active site
866768006315	hypothetical protein; Provisional; Region: PRK10292
866768006316	hypothetical protein; Provisional; Region: PRK09898
866768006317	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
866768006318	putative oxidoreductase; Provisional; Region: PRK09849
866768006319	Aldehyde ferredoxin oxidoreductase, N-terminal domain; Region: AFOR_N; pfam02730
866768006320	Aldehyde ferredoxin oxidoreductase, domains 2 & 3; Region: AFOR_C; pfam01314
866768006321	hypothetical protein; Provisional; Region: PRK09947
866768006322	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
866768006323	thiosulfate reductase cytochrome B subunit; Provisional; Region: PRK15006
866768006324	Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion]; Region: COG4117
866768006325	hypothetical protein; Provisional; Region: PRK09946
866768006326	hypothetical protein; Provisional; Region: PRK09897
866768006327	FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454
866768006328	putative monooxygenase; Provisional; Region: PRK11118
866768006329	hypothetical protein; Provisional; Region: PRK09945
866768006330	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
866768006331	multidrug efflux protein; Reviewed; Region: PRK01766
866768006332	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
866768006333	cation binding site [ion binding]; other site
866768006334	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
866768006335	Lumazine binding domain; Region: Lum_binding; pfam00677
866768006336	Lumazine binding domain; Region: Lum_binding; pfam00677
866768006337	cyclopropane fatty acyl phospholipid synthase; Provisional; Region: PRK11705
866768006338	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
866768006339	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768006340	S-adenosylmethionine binding site [chemical binding]; other site
866768006341	putative transporter; Provisional; Region: PRK11043
866768006342	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768006343	putative substrate translocation pore; other site
866768006344	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
866768006345	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768006346	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
866768006347	dimerization interface [polypeptide binding]; other site
866768006348	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
866768006349	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
866768006350	DNA binding site [nucleotide binding]
866768006351	domain linker motif; other site
866768006352	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
866768006353	dimerization interface [polypeptide binding]; other site
866768006354	ligand binding site [chemical binding]; other site
866768006355	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768006356	Major Facilitator Superfamily; Region: MFS_1; pfam07690
866768006357	putative substrate translocation pore; other site
866768006358	superoxide dismutase; Provisional; Region: PRK10543
866768006359	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
866768006360	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
866768006361	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
866768006362	NlpC/P60 family; Region: NLPC_P60; pfam00877
866768006363	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
866768006364	putative GSH binding site [chemical binding]; other site
866768006365	catalytic residues [active]
866768006366	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
866768006367	putative ATP-dependent helicase Lhr; Provisional; Region: PRK09751
866768006368	ATP binding site [chemical binding]; other site
866768006369	putative Mg++ binding site [ion binding]; other site
866768006370	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
866768006371	nucleotide binding region [chemical binding]; other site
866768006372	ATP-binding site [chemical binding]; other site
866768006373	DEAD/H associated; Region: DEAD_assoc; pfam08494
866768006374	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
866768006375	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
866768006376	dimer interface [polypeptide binding]; other site
866768006377	catalytic site [active]
866768006378	putative active site [active]
866768006379	putative substrate binding site [chemical binding]; other site
866768006380	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
866768006381	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
866768006382	dimer interface [polypeptide binding]; other site
866768006383	active site
866768006384	metal binding site [ion binding]; metal-binding site
866768006385	glutathione binding site [chemical binding]; other site
866768006386	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
866768006387	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
866768006388	FMN binding site [chemical binding]; other site
866768006389	active site
866768006390	substrate binding site [chemical binding]; other site
866768006391	catalytic residue [active]
866768006392	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
866768006393	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
866768006394	Predicted Fe-S protein [General function prediction only]; Region: COG3313
866768006395	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
866768006396	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
866768006397	active site
866768006398	catalytic tetrad [active]
866768006399	Cu/Zn superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodC; COG2032
866768006400	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
866768006401	E-class dimer interface [polypeptide binding]; other site
866768006402	P-class dimer interface [polypeptide binding]; other site
866768006403	active site
866768006404	Cu2+ binding site [ion binding]; other site
866768006405	Zn2+ binding site [ion binding]; other site
866768006406	Fusaric acid resistance protein family; Region: FUSC; pfam04632
866768006407	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
866768006408	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
866768006409	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
866768006410	HlyD family secretion protein; Region: HlyD_3; pfam13437
866768006411	Protein of unknown function (DUF1656); Region: DUF1656; cl11658
866768006412	transcriptional regulator SlyA; Provisional; Region: PRK03573
866768006413	Winged helix DNA-binding domain; Region: HTH_27; pfam13463
866768006414	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
866768006415	Uncharacterized protein family (UPF0075); Region: UPF0075; pfam03702
866768006416	lysozyme inhibitor; Provisional; Region: PRK11372
866768006417	Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864
866768006418	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
866768006419	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
866768006420	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
866768006421	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
866768006422	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
866768006423	active site
866768006424	HIGH motif; other site
866768006425	dimer interface [polypeptide binding]; other site
866768006426	KMSKS motif; other site
866768006427	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
866768006428	RNA binding surface [nucleotide binding]; other site
866768006429	pyridoxamine kinase; Validated; Region: PRK05756
866768006430	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
866768006431	dimer interface [polypeptide binding]; other site
866768006432	pyridoxal binding site [chemical binding]; other site
866768006433	ATP binding site [chemical binding]; other site
866768006434	glutathionine S-transferase; Provisional; Region: PRK10542
866768006435	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
866768006436	C-terminal domain interface [polypeptide binding]; other site
866768006437	GSH binding site (G-site) [chemical binding]; other site
866768006438	dimer interface [polypeptide binding]; other site
866768006439	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
866768006440	N-terminal domain interface [polypeptide binding]; other site
866768006441	dimer interface [polypeptide binding]; other site
866768006442	substrate binding pocket (H-site) [chemical binding]; other site
866768006443	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
866768006444	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768006445	putative substrate translocation pore; other site
866768006446	POT family; Region: PTR2; pfam00854
866768006447	endonuclease III; Provisional; Region: PRK10702
866768006448	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
866768006449	minor groove reading motif; other site
866768006450	helix-hairpin-helix signature motif; other site
866768006451	substrate binding pocket [chemical binding]; other site
866768006452	active site
866768006453	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
866768006454	electron transport complex RsxE subunit; Provisional; Region: PRK12405
866768006455	electron transport complex protein RnfG; Validated; Region: PRK01908
866768006456	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
866768006457	electron transport complex, RnfABCDGE type, C subunit; Region: rnfC; TIGR01945
866768006458	SLBB domain; Region: SLBB; pfam10531
866768006459	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
866768006460	electron transport complex protein RnfB; Provisional; Region: PRK05113
866768006461	Putative Fe-S cluster; Region: FeS; pfam04060
866768006462	4Fe-4S binding domain; Region: Fer4; pfam00037
866768006463	electron transport complex protein RsxA; Provisional; Region: PRK05151
866768006464	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
866768006465	oriC-binding nucleoid-associated protein; Provisional; Region: PRK10391
866768006466	putative oxidoreductase; Provisional; Region: PRK11579
866768006467	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
866768006468	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
866768006469	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
866768006470	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
866768006471	active site
866768006472	purine riboside binding site [chemical binding]; other site
866768006473	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
866768006474	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
866768006475	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768006476	homodimer interface [polypeptide binding]; other site
866768006477	catalytic residue [active]
866768006478	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
866768006479	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
866768006480	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
866768006481	active site turn [active]
866768006482	phosphorylation site [posttranslational modification]
866768006483	DNA-binding transcriptional repressor MalI; Provisional; Region: PRK10014
866768006484	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
866768006485	DNA binding site [nucleotide binding]
866768006486	domain linker motif; other site
866768006487	Ligand-binding domain of MalI, a transcription regulator of the maltose system of Escherichia coli and its close homologs from other bacteria; Region: PBP1_MalI_like; cd06289
866768006488	putative dimerization interface [polypeptide binding]; other site
866768006489	putative ligand binding site [chemical binding]; other site
866768006490	7-alpha-hydroxysteroid dehydrogenase; Validated; Region: PRK06113
866768006491	7 alpha-hydroxysteroid dehydrogenase (7 alpha-HSDH), classical (c) SDRs; Region: 7_alpha_HSDH_SDR_c; cd05365
866768006492	NAD binding site [chemical binding]; other site
866768006493	substrate binding site [chemical binding]; other site
866768006494	homotetramer interface [polypeptide binding]; other site
866768006495	homodimer interface [polypeptide binding]; other site
866768006496	active site
866768006497	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
866768006498	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
866768006499	beta-D-glucuronidase; Provisional; Region: PRK10150
866768006500	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
866768006501	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
866768006502	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
866768006503	glucuronide transporter; Provisional; Region: PRK09848
866768006504	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
866768006505	putative outer membrane porin protein; Provisional; Region: PRK11379
866768006506	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
866768006507	Bacterial protein of unknown function (DUF945); Region: DUF945; pfam06097
866768006508	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
866768006509	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
866768006510	mannose-6-phosphate isomerase, class I; Region: manA; TIGR00218
866768006511	fumarate hydratase; Provisional; Region: PRK15389
866768006512	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
866768006513	Fumarase C-terminus; Region: Fumerase_C; pfam05683
866768006514	fumarate hydratase; Reviewed; Region: fumC; PRK00485
866768006515	Class II fumarases; Region: Fumarase_classII; cd01362
866768006516	active site
866768006517	tetramer interface [polypeptide binding]; other site
866768006518	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
866768006519	sensor protein RstB; Provisional; Region: PRK10604
866768006520	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
866768006521	dimerization interface [polypeptide binding]; other site
866768006522	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
866768006523	dimer interface [polypeptide binding]; other site
866768006524	phosphorylation site [posttranslational modification]
866768006525	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866768006526	ATP binding site [chemical binding]; other site
866768006527	Mg2+ binding site [ion binding]; other site
866768006528	G-X-G motif; other site
866768006529	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
866768006530	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768006531	active site
866768006532	phosphorylation site [posttranslational modification]
866768006533	intermolecular recognition site; other site
866768006534	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
866768006535	DNA binding site [nucleotide binding]
866768006536	GlpM protein; Region: GlpM; pfam06942
866768006537	dihydromonapterin reductase; Provisional; Region: PRK06483
866768006538	pteridine reductase (PR), classical (c) SDRs; Region: PR_SDR_c; cd05357
866768006539	NADP binding site [chemical binding]; other site
866768006540	substrate binding pocket [chemical binding]; other site
866768006541	active site
866768006542	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
866768006543	Spore germination protein; Region: Spore_permease; cl17796
866768006544	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
866768006545	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
866768006546	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
866768006547	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
866768006548	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
866768006549	ligand binding site [chemical binding]; other site
866768006550	homodimer interface [polypeptide binding]; other site
866768006551	NAD(P) binding site [chemical binding]; other site
866768006552	trimer interface B [polypeptide binding]; other site
866768006553	trimer interface A [polypeptide binding]; other site
866768006554	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
866768006555	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
866768006556	NAD(P) transhydrogenase beta subunit; Region: PNTB; pfam02233
866768006557	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; PRK12287
866768006558	Domain of unknown function DUF20; Region: UPF0118; pfam01594
866768006559	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
866768006560	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
866768006561	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
866768006562	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
866768006563	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768006564	putative substrate translocation pore; other site
866768006565	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
866768006566	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768006567	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
866768006568	dimerization interface [polypeptide binding]; other site
866768006569	substrate binding pocket [chemical binding]; other site
866768006570	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
866768006571	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
866768006572	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
866768006573	nucleotide binding site [chemical binding]; other site
866768006574	putative dithiobiotin synthetase; Provisional; Region: PRK12374
866768006575	AAA domain; Region: AAA_26; pfam13500
866768006576	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
866768006577	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
866768006578	Cl- selectivity filter; other site
866768006579	Cl- binding residues [ion binding]; other site
866768006580	pore gating glutamate residue; other site
866768006581	dimer interface [polypeptide binding]; other site
866768006582	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
866768006583	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
866768006584	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
866768006585	4Fe-4S binding domain; Region: Fer4; cl02805
866768006586	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
866768006587	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
866768006588	putative [Fe4-S4] binding site [ion binding]; other site
866768006589	putative molybdopterin cofactor binding site [chemical binding]; other site
866768006590	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
866768006591	putative molybdopterin cofactor binding site; other site
866768006592	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
866768006593	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
866768006594	putative [Fe4-S4] binding site [ion binding]; other site
866768006595	putative molybdopterin cofactor binding site [chemical binding]; other site
866768006596	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
866768006597	putative molybdopterin cofactor binding site; other site
866768006598	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
866768006599	Uncharacterized protein family (UPF0257); Region: UPF0257; pfam06788
866768006600	spermidine N1-acetyltransferase; Provisional; Region: PRK15130
866768006601	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
866768006602	Coenzyme A binding pocket [chemical binding]; other site
866768006603	hypothetical protein; Provisional; Region: PRK13659
866768006604	hypothetical protein; Provisional; Region: PRK02237
866768006605	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
866768006606	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
866768006607	putative active site pocket [active]
866768006608	putative metal binding site [ion binding]; other site
866768006609	putative oxidoreductase; Provisional; Region: PRK10083
866768006610	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
866768006611	putative NAD(P) binding site [chemical binding]; other site
866768006612	catalytic Zn binding site [ion binding]; other site
866768006613	structural Zn binding site [ion binding]; other site
866768006614	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
866768006615	DicB protein; Region: DicB; pfam05358
866768006616	transcriptional repressor DicA; Reviewed; Region: PRK09706
866768006617	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
866768006618	non-specific DNA binding site [nucleotide binding]; other site
866768006619	salt bridge; other site
866768006620	sequence-specific DNA binding site [nucleotide binding]; other site
866768006621	DNA-binding transcriptional regulator DicC; Provisional; Region: PRK09744
866768006622	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
866768006623	primosomal protein DnaI; Provisional; Region: PRK02854
866768006624	Bacterial protein of unknown function (DUF977); Region: DUF977; pfam06163
866768006625	Hok/gef family; Region: HOK_GEF; pfam01848
866768006626	Protein of unknown function (DUF968); Region: DUF968; pfam06147
866768006627	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
866768006628	outer membrane lipoprotein Blc; Provisional; Region: PRK10477
866768006629	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
866768006630	Protein of unknown function (DUF523); Region: DUF523; pfam04463
866768006631	putative transposase OrfB; Reviewed; Region: PHA02517
866768006632	HTH-like domain; Region: HTH_21; pfam13276
866768006633	Integrase core domain; Region: rve; pfam00665
866768006634	Integrase core domain; Region: rve_2; pfam13333
866768006635	Transposase; Region: HTH_Tnp_1; cl17663
866768006636	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
866768006637	Chaperone of endosialidase; Region: Peptidase_S74; pfam13884
866768006638	multiple promoter invertase; Provisional; Region: mpi; PRK13413
866768006639	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
866768006640	catalytic residues [active]
866768006641	catalytic nucleophile [active]
866768006642	Presynaptic Site I dimer interface [polypeptide binding]; other site
866768006643	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
866768006644	Synaptic Flat tetramer interface [polypeptide binding]; other site
866768006645	Synaptic Site I dimer interface [polypeptide binding]; other site
866768006646	DNA binding site [nucleotide binding]
866768006647	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
866768006648	DNA-binding interface [nucleotide binding]; DNA binding site
866768006649	metabolite-proton symporter; Region: 2A0106; TIGR00883
866768006650	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768006651	putative substrate translocation pore; other site
866768006652	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
866768006653	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
866768006654	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
866768006655	putative selenium-binding protein YdfZ; Region: YdfZ_fam; TIGR03318
866768006656	Transcriptional regulators [Transcription]; Region: GntR; COG1802
866768006657	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
866768006658	DNA-binding site [nucleotide binding]; DNA binding site
866768006659	FCD domain; Region: FCD; pfam07729
866768006660	malonic semialdehyde reductase; Provisional; Region: PRK10538
866768006661	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
866768006662	putative NAD(P) binding site [chemical binding]; other site
866768006663	homodimer interface [polypeptide binding]; other site
866768006664	homotetramer interface [polypeptide binding]; other site
866768006665	active site
866768006666	dipeptidyl carboxypeptidase II; Provisional; Region: PRK10280
866768006667	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
866768006668	active site
866768006669	Zn binding site [ion binding]; other site
866768006670	hypothetical protein; Validated; Region: PRK03657
866768006671	hypothetical protein; Provisional; Region: PRK10053
866768006672	diguanylate cyclase; Provisional; Region: PRK09894
866768006673	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
866768006674	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
866768006675	metal binding site [ion binding]; metal-binding site
866768006676	active site
866768006677	I-site; other site
866768006678	putative transporter; Provisional; Region: PRK10054
866768006679	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768006680	putative substrate translocation pore; other site
866768006681	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
866768006682	EamA-like transporter family; Region: EamA; pfam00892
866768006683	EamA-like transporter family; Region: EamA; pfam00892
866768006684	hypothetical protein; Provisional; Region: PRK10106
866768006685	DNA-binding transcriptional activator MarA; Provisional; Region: PRK11511
866768006686	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768006687	DNA-binding transcriptional repressor MarR; Provisional; Region: PRK11512
866768006688	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
866768006689	Phage derived protein Gp49-like (DUF891); Region: Gp49; pfam05973
866768006690	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
866768006691	non-specific DNA binding site [nucleotide binding]; other site
866768006692	salt bridge; other site
866768006693	sequence-specific DNA binding site [nucleotide binding]; other site
866768006694	inner membrane protein; Provisional; Region: PRK10995
866768006695	putative arabinose transporter; Provisional; Region: PRK03545
866768006696	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768006697	putative substrate translocation pore; other site
866768006698	Transcriptional regulator [Transcription]; Region: LysR; COG0583
866768006699	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768006700	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
866768006701	putative dimerization interface [polypeptide binding]; other site
866768006702	putative succinate semialdehyde dehydrogenase; Provisional; Region: PRK13968
866768006703	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
866768006704	NAD(P) binding site [chemical binding]; other site
866768006705	catalytic residues [active]
866768006706	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
866768006707	glutaminase; Provisional; Region: PRK00971
866768006708	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
866768006709	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
866768006710	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
866768006711	metal binding site [ion binding]; metal-binding site
866768006712	active site
866768006713	I-site; other site
866768006714	altronate oxidoreductase; Provisional; Region: PRK03643
866768006715	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
866768006716	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
866768006717	Predicted membrane protein [Function unknown]; Region: COG3781
866768006718	Trans-aconitate methyltransferase [General function prediction only]; Region: Tam; COG4106
866768006719	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768006720	S-adenosylmethionine binding site [chemical binding]; other site
866768006721	autoinducer-2 (AI-2) modifying protein LsrG; Provisional; Region: PRK10486
866768006722	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
866768006723	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
866768006724	putative active site; other site
866768006725	catalytic residue [active]
866768006726	autoinducer 2-binding protein lsrB; Provisional; Region: PRK15408
866768006727	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
866768006728	ligand binding site [chemical binding]; other site
866768006729	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
866768006730	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
866768006731	Autotransporter beta-domain; Region: Autotransporter; pfam03797
866768006732	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
866768006733	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
866768006734	non-specific DNA binding site [nucleotide binding]; other site
866768006735	salt bridge; other site
866768006736	sequence-specific DNA binding site [nucleotide binding]; other site
866768006737	HipA N-terminal domain; Region: Couple_hipA; pfam13657
866768006738	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
866768006739	HipA-like N-terminal domain; Region: HipA_N; pfam07805
866768006740	HipA-like C-terminal domain; Region: HipA_C; pfam07804
866768006741	Fimbrial protein; Region: Fimbrial; cl01416
866768006742	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
866768006743	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
866768006744	Mannose binding  domain of FimH and related proteins; Region: FimH_man-bind; cd10466
866768006745	mannosyl binding site [chemical binding]; other site
866768006746	Fimbrial protein; Region: Fimbrial; pfam00419
866768006747	putative oxidoreductase; Provisional; Region: PRK09939
866768006748	The MopB_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins; Region: MopB_ydeP; cd02767
866768006749	putative molybdopterin cofactor binding site [chemical binding]; other site
866768006750	The MopB_CT_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. This CD is of the conserved molybdopterin_binding C-terminal (MopB_CT) region...; Region: MopB_CT_ydeP; cd02787
866768006751	putative molybdopterin cofactor binding site; other site
866768006752	transcriptional regulator YdeO; Provisional; Region: PRK09940
866768006753	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768006754	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
866768006755	Sulfatase; Region: Sulfatase; pfam00884
866768006756	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
866768006757	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866768006758	FeS/SAM binding site; other site
866768006759	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
866768006760	ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only]; Region: COG4178
866768006761	ABC transporter transmembrane region 2; Region: ABC_membrane_2; cl00549
866768006762	ATP-binding cassette domain of peroxisomal transporter, subfamily D; Region: ABCD_peroxisomal_ALDP; cd03223
866768006763	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
866768006764	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
866768006765	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
866768006766	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
866768006767	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
866768006768	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
866768006769	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
866768006770	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
866768006771	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768006772	catalytic residue [active]
866768006773	glutamate:gamma-aminobutyrate antiporter; Region: 2A0307_GadC; TIGR00910
866768006774	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1649
866768006775	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
866768006776	Globin domain present in Globin-Coupled-Sensors (GCS). These domains detect changes in intracellular concentrations of oxygen, carbon monoxyde, or nitrous oxide,  which result in aerotaxis and/or gene regulation. One subgroup, the HemATs, are aerotactic...; Region: sensor_globin; cd01068
866768006777	heme-binding site [chemical binding]; other site
866768006778	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
866768006779	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
866768006780	metal binding site [ion binding]; metal-binding site
866768006781	active site
866768006782	I-site; other site
866768006783	cyclic-di-GMP phosphodiesterase; Provisional; Region: PRK11359
866768006784	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
866768006785	putative active site [active]
866768006786	heme pocket [chemical binding]; other site
866768006787	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
866768006788	putative active site [active]
866768006789	heme pocket [chemical binding]; other site
866768006790	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
866768006791	metal binding site [ion binding]; metal-binding site
866768006792	active site
866768006793	I-site; other site
866768006794	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
866768006795	D-alanyl-D-alanine dipeptidase; Provisional; Region: PRK10178
866768006796	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
866768006797	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512
866768006798	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
866768006799	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768006800	dimer interface [polypeptide binding]; other site
866768006801	conserved gate region; other site
866768006802	putative PBP binding loops; other site
866768006803	ABC-ATPase subunit interface; other site
866768006804	D-ala-D-ala transporter subunit; Provisional; Region: PRK09881
866768006805	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
866768006806	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768006807	dimer interface [polypeptide binding]; other site
866768006808	conserved gate region; other site
866768006809	putative PBP binding loops; other site
866768006810	ABC-ATPase subunit interface; other site
866768006811	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
866768006812	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
866768006813	Walker A/P-loop; other site
866768006814	ATP binding site [chemical binding]; other site
866768006815	Q-loop/lid; other site
866768006816	ABC transporter signature motif; other site
866768006817	Walker B; other site
866768006818	D-loop; other site
866768006819	H-loop/switch region; other site
866768006820	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
866768006821	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
866768006822	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
866768006823	Walker A/P-loop; other site
866768006824	ATP binding site [chemical binding]; other site
866768006825	Q-loop/lid; other site
866768006826	ABC transporter signature motif; other site
866768006827	Walker B; other site
866768006828	D-loop; other site
866768006829	H-loop/switch region; other site
866768006830	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
866768006831	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
866768006832	Putative biofilm-dependent modulation protein; Region: BDM; cl11581
866768006833	30S ribosomal subunit S22; Reviewed; Region: rpsV; PRK10057
866768006834	malate dehydrogenase; Provisional; Region: PRK13529
866768006835	Malic enzyme, N-terminal domain; Region: malic; pfam00390
866768006836	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
866768006837	NAD(P) binding site [chemical binding]; other site
866768006838	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
866768006839	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
866768006840	NAD binding site [chemical binding]; other site
866768006841	substrate binding site [chemical binding]; other site
866768006842	catalytic Zn binding site [ion binding]; other site
866768006843	tetramer interface [polypeptide binding]; other site
866768006844	structural Zn binding site [ion binding]; other site
866768006845	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
866768006846	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
866768006847	non-specific DNA binding site [nucleotide binding]; other site
866768006848	salt bridge; other site
866768006849	sequence-specific DNA binding site [nucleotide binding]; other site
866768006850	formate dehydrogenase-N subunit gamma; Provisional; Region: PRK10179
866768006851	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
866768006852	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
866768006853	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
866768006854	formate dehydrogenase, alpha subunit, proteobacterial-type; Region: formate-DH-alph; TIGR01553
866768006855	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
866768006856	[4Fe-4S] binding site [ion binding]; other site
866768006857	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
866768006858	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
866768006859	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
866768006860	molybdopterin cofactor binding site; other site
866768006861	aromatic amino acid exporter; Provisional; Region: PRK11689
866768006862	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
866768006863	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
866768006864	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
866768006865	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
866768006866	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
866768006867	[4Fe-4S] binding site [ion binding]; other site
866768006868	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
866768006869	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
866768006870	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
866768006871	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
866768006872	molybdopterin cofactor binding site; other site
866768006873	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
866768006874	nitrate reductase 2 subunit delta; Provisional; Region: PRK15054
866768006875	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
866768006876	N-hydroxyarylamine O-acetyltransferase; Provisional; Region: PRK15047
866768006877	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
866768006878	4-oxalocrotonate tautomerase; Provisional; Region: PRK01271
866768006879	active site 1 [active]
866768006880	dimer interface [polypeptide binding]; other site
866768006881	hexamer interface [polypeptide binding]; other site
866768006882	active site 2 [active]
866768006883	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
866768006884	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
866768006885	Transposase [DNA replication, recombination, and repair]; Region: COG5433
866768006886	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
866768006887	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
866768006888	C-terminal domain interface [polypeptide binding]; other site
866768006889	GSH binding site (G-site) [chemical binding]; other site
866768006890	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
866768006891	dimer interface [polypeptide binding]; other site
866768006892	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
866768006893	dimer interface [polypeptide binding]; other site
866768006894	N-terminal domain interface [polypeptide binding]; other site
866768006895	substrate binding pocket (H-site) [chemical binding]; other site
866768006896	L-asparagine permease; Provisional; Region: PRK15049
866768006897	PQQ-like domain; Region: PQQ_2; pfam13360
866768006898	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
866768006899	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
866768006900	N-terminal plug; other site
866768006901	ligand-binding site [chemical binding]; other site
866768006902	colanic acid/biofilm transcriptional regulator; Provisional; Region: PRK11414
866768006903	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
866768006904	DNA-binding site [nucleotide binding]; DNA binding site
866768006905	FCD domain; Region: FCD; pfam07729
866768006906	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
866768006907	Prostaglandin dehydrogenases; Region: PGDH; cd05288
866768006908	NAD(P) binding site [chemical binding]; other site
866768006909	substrate binding site [chemical binding]; other site
866768006910	dimer interface [polypeptide binding]; other site
866768006911	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
866768006912	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
866768006913	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
866768006914	Protein of unknown function (DUF2526); Region: DUF2526; pfam10735
866768006915	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
866768006916	gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK13473
866768006917	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
866768006918	tetrameric interface [polypeptide binding]; other site
866768006919	NAD binding site [chemical binding]; other site
866768006920	catalytic residues [active]
866768006921	substrate binding site [chemical binding]; other site
866768006922	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
866768006923	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768006924	ABC-ATPase subunit interface; other site
866768006925	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768006926	dimer interface [polypeptide binding]; other site
866768006927	conserved gate region; other site
866768006928	putative PBP binding loops; other site
866768006929	ABC-ATPase subunit interface; other site
866768006930	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
866768006931	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866768006932	Walker A/P-loop; other site
866768006933	ATP binding site [chemical binding]; other site
866768006934	Q-loop/lid; other site
866768006935	ABC transporter signature motif; other site
866768006936	Walker B; other site
866768006937	D-loop; other site
866768006938	H-loop/switch region; other site
866768006939	TOBE domain; Region: TOBE_2; pfam08402
866768006940	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
866768006941	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
866768006942	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
866768006943	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
866768006944	DNA-binding site [nucleotide binding]; DNA binding site
866768006945	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
866768006946	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768006947	homodimer interface [polypeptide binding]; other site
866768006948	catalytic residue [active]
866768006949	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: COG1598
866768006950	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
866768006951	sequence-specific DNA binding site [nucleotide binding]; other site
866768006952	salt bridge; other site
866768006953	YcfA-like protein; Region: YcfA; pfam07927
866768006954	Protein of unknown function (DUF2554); Region: DUF2554; pfam10829
866768006955	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
866768006956	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
866768006957	Peptidase family U32; Region: Peptidase_U32; pfam01136
866768006958	Collagenase; Region: DUF3656; pfam12392
866768006959	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
866768006960	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
866768006961	non-specific DNA binding site [nucleotide binding]; other site
866768006962	salt bridge; other site
866768006963	sequence-specific DNA binding site [nucleotide binding]; other site
866768006964	Cupin domain; Region: Cupin_2; pfam07883
866768006965	Uncharacterized protein involved in benzoate metabolism [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BenE; COG3135
866768006966	benzoate transporter; Region: benE; TIGR00843
866768006967	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
866768006968	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
866768006969	Probable transposase; Region: OrfB_IS605; pfam01385
866768006970	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
866768006971	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
866768006972	tellurite resistance protein TehB; Provisional; Region: PRK11207
866768006973	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768006974	S-adenosylmethionine binding site [chemical binding]; other site
866768006975	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
866768006976	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
866768006977	gating phenylalanine in ion channel; other site
866768006978	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
866768006979	putative trimer interface [polypeptide binding]; other site
866768006980	putative CoA binding site [chemical binding]; other site
866768006981	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cd00208
866768006982	putative trimer interface [polypeptide binding]; other site
866768006983	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
866768006984	putative CoA binding site [chemical binding]; other site
866768006985	putative trimer interface [polypeptide binding]; other site
866768006986	putative CoA binding site [chemical binding]; other site
866768006987	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
866768006988	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
866768006989	Coenzyme A binding pocket [chemical binding]; other site
866768006990	hypothetical protein; Provisional; Region: PRK11415
866768006991	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
866768006992	glucan biosynthesis protein D; Provisional; Region: mdoD; PRK13273
866768006993	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
866768006994	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
866768006995	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
866768006996	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768006997	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
866768006998	dimerization interface [polypeptide binding]; other site
866768006999	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
866768007000	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
866768007001	dimer interface [polypeptide binding]; other site
866768007002	ligand binding site [chemical binding]; other site
866768007003	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
866768007004	dimerization interface [polypeptide binding]; other site
866768007005	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
866768007006	dimer interface [polypeptide binding]; other site
866768007007	putative CheW interface [polypeptide binding]; other site
866768007008	hypothetical protein; Provisional; Region: PRK10040
866768007009	cytochrome b561; Provisional; Region: PRK11513
866768007010	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
866768007011	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
866768007012	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
866768007013	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
866768007014	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
866768007015	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
866768007016	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
866768007017	Escherichia coli lactaldehyde dehydrogenase AldA-like; Region: ALDH_LactADH-AldA; cd07088
866768007018	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
866768007019	NAD binding site [chemical binding]; other site
866768007020	catalytic residues [active]
866768007021	substrate binding site [chemical binding]; other site
866768007022	Uncharacterized conserved protein [Function unknown]; Region: COG1434
866768007023	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
866768007024	putative active site [active]
866768007025	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
866768007026	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
866768007027	ATP binding site [chemical binding]; other site
866768007028	putative Mg++ binding site [ion binding]; other site
866768007029	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
866768007030	nucleotide binding region [chemical binding]; other site
866768007031	ATP-binding site [chemical binding]; other site
866768007032	Helicase associated domain (HA2); Region: HA2; pfam04408
866768007033	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
866768007034	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
866768007035	azoreductase; Reviewed; Region: PRK00170
866768007036	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
866768007037	PAP2_like proteins, Aur1_like subfamily. Yeast Aur1p or Ipc1p is necessary for the addition of inositol phosphate to ceramide, an essential step in yeast sphingolipid synthesis, and is the target of several antifungal compounds such as aureobasidin; Region: PAP2_Aur1_like; cd03386
866768007038	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
866768007039	active site
866768007040	Dual specificity phosphatase, catalytic domain; Region: DSPc; smart00195
866768007041	active site
866768007042	catalytic residues [active]
866768007043	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
866768007044	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
866768007045	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768007046	S-adenosylmethionine binding site [chemical binding]; other site
866768007047	Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase [General function prediction only]; Region: COG4589
866768007048	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
866768007049	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
866768007050	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
866768007051	Protein of unknown function (DUF2773); Region: DUF2773; pfam10971
866768007052	putative transposase OrfB; Reviewed; Region: PHA02517
866768007053	HTH-like domain; Region: HTH_21; pfam13276
866768007054	Integrase core domain; Region: rve; pfam00665
866768007055	Integrase core domain; Region: rve_2; pfam13333
866768007056	Transposase; Region: HTH_Tnp_1; cl17663
866768007057	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
866768007058	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
866768007059	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
866768007060	NAD(P) binding site [chemical binding]; other site
866768007061	catalytic residues [active]
866768007062	DNA-binding transcriptional activator FeaR; Provisional; Region: PRK09685
866768007063	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768007064	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3784
866768007065	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
866768007066	hypothetical protein; Provisional; Region: PRK10695
866768007067	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
866768007068	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
866768007069	putative ligand binding site [chemical binding]; other site
866768007070	putative NAD binding site [chemical binding]; other site
866768007071	catalytic site [active]
866768007072	heat-inducible protein; Provisional; Region: PRK10449
866768007073	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
866768007074	Domain of unknown function (DUF333); Region: DUF333; pfam03891
866768007075	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
866768007076	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
866768007077	dimer interface [polypeptide binding]; other site
866768007078	PYR/PP interface [polypeptide binding]; other site
866768007079	TPP binding site [chemical binding]; other site
866768007080	substrate binding site [chemical binding]; other site
866768007081	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
866768007082	Domain of unknown function; Region: EKR; smart00890
866768007083	4Fe-4S binding domain; Region: Fer4_6; pfam12837
866768007084	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
866768007085	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
866768007086	TPP-binding site [chemical binding]; other site
866768007087	dimer interface [polypeptide binding]; other site
866768007088	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
866768007089	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
866768007090	trimer interface [polypeptide binding]; other site
866768007091	eyelet of channel; other site
866768007092	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
866768007093	Ligand Binding Site [chemical binding]; other site
866768007094	multiple promoter invertase; Provisional; Region: mpi; PRK13413
866768007095	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
866768007096	catalytic residues [active]
866768007097	catalytic nucleophile [active]
866768007098	Presynaptic Site I dimer interface [polypeptide binding]; other site
866768007099	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
866768007100	Synaptic Flat tetramer interface [polypeptide binding]; other site
866768007101	Synaptic Site I dimer interface [polypeptide binding]; other site
866768007102	DNA binding site [nucleotide binding]
866768007103	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cd00569
866768007104	DNA-binding interface [nucleotide binding]; DNA binding site
866768007105	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
866768007106	ParB-like nuclease domain; Region: ParBc; pfam02195
866768007107	Cation transport protein; Region: TrkH; cl17365
866768007108	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
866768007109	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
866768007110	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
866768007111	catalytic residues [active]
866768007112	Protein of unknown function (DUF1327); Region: DUF1327; pfam07041
866768007113	Lysis protein S; Region: Lysis_S; pfam04971
866768007114	Protein of unknown function (DUF1391); Region: DUF1391; pfam07151
866768007115	Superinfection exclusion protein B; Region: SieB; pfam14163
866768007116	FtsZ inhibitor protein; Reviewed; Region: kil; PRK11354
866768007117	hypothetical protein; Reviewed; Region: PRK09790
866768007118	recombination and repair protein RecT; Reviewed; Region: recT; PRK09846
866768007119	hypothetical protein; Provisional; Region: PRK09750
866768007120	Putative excisionase (DUF1233); Region: DUF1233; pfam06806
866768007121	Domain of unknown function (DUF3596); Region: DUF3596; pfam12167
866768007122	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
866768007123	phiCTX phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various phage and bacterial integrases, including those similar to phage integrases: Bordetella and...; Region: INT_phiCTX_C; cd01191
866768007124	Int/Topo IB signature motif; other site
866768007125	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
866768007126	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
866768007127	Ligand Binding Site [chemical binding]; other site
866768007128	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
866768007129	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
866768007130	ATP binding site [chemical binding]; other site
866768007131	Mg++ binding site [ion binding]; other site
866768007132	motif III; other site
866768007133	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
866768007134	nucleotide binding region [chemical binding]; other site
866768007135	ATP-binding site [chemical binding]; other site
866768007136	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
866768007137	putative RNA binding site [nucleotide binding]; other site
866768007138	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
866768007139	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
866768007140	Cl binding site [ion binding]; other site
866768007141	oligomer interface [polypeptide binding]; other site
866768007142	PAS domain S-box; Region: sensory_box; TIGR00229
866768007143	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
866768007144	putative active site [active]
866768007145	heme pocket [chemical binding]; other site
866768007146	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
866768007147	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
866768007148	metal binding site [ion binding]; metal-binding site
866768007149	active site
866768007150	I-site; other site
866768007151	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
866768007152	Smr domain; Region: Smr; pfam01713
866768007153	putative DNA-binding transcriptional regulator; Provisional; Region: PRK09791
866768007154	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768007155	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
866768007156	putative substrate binding pocket [chemical binding]; other site
866768007157	putative dimerization interface [polypeptide binding]; other site
866768007158	M20 Peptidases Aminoacyclase-1 indole-3-acetic-L-aspartic acid hydrolase from bacteria and archaea; Region: M20_Acy1_IAAspH_bact; cd05665
866768007159	amidohydrolase; Region: amidohydrolases; TIGR01891
866768007160	putative metal binding site [ion binding]; other site
866768007161	dimer interface [polypeptide binding]; other site
866768007162	M20 Peptidase Aminoacylase 1-like protein 2 aminobenzoyl-glutamate utilization protein B subfamily; Region: M20_Acy1L2_AbgB; cd05673
866768007163	amidohydrolase; Region: amidohydrolases; TIGR01891
866768007164	putative metal binding site [ion binding]; other site
866768007165	putative aminobenzoyl-glutamate transporter; Provisional; Region: abgT; PRK11339
866768007166	p-Aminobenzoyl-glutamate transporter family; Region: ydaH; TIGR00819
866768007167	O-6-alkylguanine-DNA:cysteine-protein methyltransferase; Provisional; Region: PRK10286
866768007168	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
866768007169	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
866768007170	DNA binding site [nucleotide binding]
866768007171	active site
866768007172	universal stress protein UspE; Provisional; Region: PRK11175
866768007173	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
866768007174	Ligand Binding Site [chemical binding]; other site
866768007175	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
866768007176	Ligand Binding Site [chemical binding]; other site
866768007177	Protein of unknown function (DUF2534); Region: DUF2534; pfam10749
866768007178	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
866768007179	Mechanosensitive ion channel; Region: MS_channel; pfam00924
866768007180	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
866768007181	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
866768007182	peptide binding site [polypeptide binding]; other site
866768007183	Transcriptional regulator [Transcription]; Region: LysR; COG0583
866768007184	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768007185	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
866768007186	putative effector binding pocket; other site
866768007187	putative dimerization interface [polypeptide binding]; other site
866768007188	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
866768007189	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
866768007190	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
866768007191	Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866
866768007192	Peptidase M14-like domain of Escherichia coli Murein Peptide Amidase A and related proteins; Region: M14_MpaA_like; cd06904
866768007193	putative active site [active]
866768007194	Zn binding site [ion binding]; other site
866768007195	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
866768007196	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
866768007197	active site
866768007198	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
866768007199	dimer interface [polypeptide binding]; other site
866768007200	catalytic triad [active]
866768007201	peroxidatic and resolving cysteines [active]
866768007202	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
866768007203	N-terminal ACT domain of the TyrR protein; Region: ACT_TyrR; cd04877
866768007204	putative aromatic amino acid binding site; other site
866768007205	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866768007206	Walker A motif; other site
866768007207	ATP binding site [chemical binding]; other site
866768007208	Walker B motif; other site
866768007209	arginine finger; other site
866768007210	hypothetical protein; Provisional; Region: PRK05415
866768007211	TIGR01620 family protein; Region: hyp_HI0043
866768007212	Predicted ATPase [General function prediction only]; Region: COG3106
866768007213	Transcriptional regulators [Transcription]; Region: PurR; COG1609
866768007214	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
866768007215	DNA binding site [nucleotide binding]
866768007216	domain linker motif; other site
866768007217	Ligand-binding domain of uncharacterized transcription regulator ycjW which is a member of the LacI-GalR family repressors; Region: PBP1_ycjW_transcription_regulator_like; cd06294
866768007218	putative dimerization interface [polypeptide binding]; other site
866768007219	putative ligand binding site [chemical binding]; other site
866768007220	Outer membrane protein G (OmpG); Region: Porin_OmpG; pfam09381
866768007221	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
866768007222	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
866768007223	Walker A/P-loop; other site
866768007224	ATP binding site [chemical binding]; other site
866768007225	Q-loop/lid; other site
866768007226	ABC transporter signature motif; other site
866768007227	Walker B; other site
866768007228	D-loop; other site
866768007229	H-loop/switch region; other site
866768007230	TOBE domain; Region: TOBE_2; pfam08402
866768007231	beta-phosphoglucomutase; Region: bPGM; TIGR01990
866768007232	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866768007233	motif II; other site
866768007234	Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]; Region: ATH1; COG1554
866768007235	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
866768007236	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
866768007237	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
866768007238	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
866768007239	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
866768007240	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
866768007241	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
866768007242	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
866768007243	2-desacetyl-2-hydroxyethyl bacteriochlorophyllide and other MDR family members; Region: 2-desacetyl-2-hydroxyethyl_bacteriochlorophyllide_; cd08255
866768007244	putative NAD(P) binding site [chemical binding]; other site
866768007245	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
866768007246	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768007247	dimer interface [polypeptide binding]; other site
866768007248	conserved gate region; other site
866768007249	putative PBP binding loops; other site
866768007250	ABC-ATPase subunit interface; other site
866768007251	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
866768007252	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768007253	dimer interface [polypeptide binding]; other site
866768007254	conserved gate region; other site
866768007255	putative PBP binding loops; other site
866768007256	ABC-ATPase subunit interface; other site
866768007257	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
866768007258	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
866768007259	Alpha amylase catalytic domain found in sucrose phosphorylase-like proteins (also called sucrose glucosyltransferase, disaccharide glucosyltransferase, and sucrose-phosphate alpha-D glucosyltransferase); Region: AmyAc_Sucrose_phosphorylase-like_1; cd11356
866768007260	sucrose phosphorylase; Provisional; Region: PRK13840
866768007261	active site
866768007262	homodimer interface [polypeptide binding]; other site
866768007263	catalytic site [active]
866768007264	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
866768007265	active site residue [active]
866768007266	peripheral inner membrane phage-shock protein; Provisional; Region: PRK10497
866768007267	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
866768007268	phage shock protein C; Region: phageshock_pspC; TIGR02978
866768007269	phage shock protein B; Provisional; Region: pspB; PRK09458
866768007270	phage shock protein PspA; Provisional; Region: PRK10698
866768007271	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
866768007272	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866768007273	Walker A motif; other site
866768007274	ATP binding site [chemical binding]; other site
866768007275	Walker B motif; other site
866768007276	arginine finger; other site
866768007277	4-aminobutyrate transaminase; Provisional; Region: PRK09792
866768007278	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
866768007279	inhibitor-cofactor binding pocket; inhibition site
866768007280	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768007281	catalytic residue [active]
866768007282	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
866768007283	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
866768007284	gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK09847
866768007285	Escherichia coli NADP+-dependent gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase PuuC-like; Region: ALDH_GABALDH-PuuC; cd07112
866768007286	NAD(P) binding site [chemical binding]; other site
866768007287	catalytic residues [active]
866768007288	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
866768007289	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
866768007290	non-specific DNA binding site [nucleotide binding]; other site
866768007291	salt bridge; other site
866768007292	sequence-specific DNA binding site [nucleotide binding]; other site
866768007293	Cupin domain; Region: Cupin_2; pfam07883
866768007294	gamma-glutamyl-gamma-aminobutyrate hydrolase; Provisional; Region: puuD; PRK11366
866768007295	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
866768007296	catalytic triad [active]
866768007297	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
866768007298	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
866768007299	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
866768007300	Protein of unknown function (DUF2543); Region: DUF2543; pfam10820
866768007301	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
866768007302	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
866768007303	peptide binding site [polypeptide binding]; other site
866768007304	antimicrobial peptide ABC transporter permease SapB; Provisional; Region: PRK15110
866768007305	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768007306	dimer interface [polypeptide binding]; other site
866768007307	conserved gate region; other site
866768007308	putative PBP binding loops; other site
866768007309	ABC-ATPase subunit interface; other site
866768007310	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
866768007311	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
866768007312	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768007313	dimer interface [polypeptide binding]; other site
866768007314	conserved gate region; other site
866768007315	putative PBP binding loops; other site
866768007316	ABC-ATPase subunit interface; other site
866768007317	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
866768007318	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
866768007319	Walker A/P-loop; other site
866768007320	ATP binding site [chemical binding]; other site
866768007321	Q-loop/lid; other site
866768007322	ABC transporter signature motif; other site
866768007323	Walker B; other site
866768007324	D-loop; other site
866768007325	H-loop/switch region; other site
866768007326	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
866768007327	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
866768007328	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
866768007329	Walker A/P-loop; other site
866768007330	ATP binding site [chemical binding]; other site
866768007331	Q-loop/lid; other site
866768007332	ABC transporter signature motif; other site
866768007333	Walker B; other site
866768007334	D-loop; other site
866768007335	H-loop/switch region; other site
866768007336	Domain of unknown function, appears to be related to a diverse group of endonucleases; Region: Endonuclease_DUF559; cd01038
866768007337	putative active site [active]
866768007338	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK07984
866768007339	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
866768007340	NAD binding site [chemical binding]; other site
866768007341	homotetramer interface [polypeptide binding]; other site
866768007342	homodimer interface [polypeptide binding]; other site
866768007343	substrate binding site [chemical binding]; other site
866768007344	active site
866768007345	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950
866768007346	Uncharacterized conserved protein [Function unknown]; Region: COG2128
866768007347	exoribonuclease II; Provisional; Region: PRK05054
866768007348	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
866768007349	RNB domain; Region: RNB; pfam00773
866768007350	S1 RNA binding domain; Region: S1; pfam00575
866768007351	RNase II stability modulator; Provisional; Region: PRK10060
866768007352	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
866768007353	putative active site [active]
866768007354	heme pocket [chemical binding]; other site
866768007355	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
866768007356	metal binding site [ion binding]; metal-binding site
866768007357	active site
866768007358	I-site; other site
866768007359	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
866768007360	hypothetical protein; Provisional; Region: PRK13658
866768007361	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
866768007362	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
866768007363	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
866768007364	lipoprotein; Provisional; Region: PRK10540
866768007365	translation initiation factor Sui1; Validated; Region: PRK06824
866768007366	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
866768007367	putative rRNA binding site [nucleotide binding]; other site
866768007368	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
866768007369	active site
866768007370	dimer interface [polypeptide binding]; other site
866768007371	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
866768007372	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
866768007373	TPR motif; other site
866768007374	binding surface
866768007375	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
866768007376	binding surface
866768007377	TPR motif; other site
866768007378	Predicted membrane protein [Function unknown]; Region: COG3771
866768007379	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
866768007380	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
866768007381	active site
866768007382	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
866768007383	dimerization interface [polypeptide binding]; other site
866768007384	active site
866768007385	aconitate hydratase; Validated; Region: PRK09277
866768007386	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
866768007387	substrate binding site [chemical binding]; other site
866768007388	ligand binding site [chemical binding]; other site
866768007389	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
866768007390	substrate binding site [chemical binding]; other site
866768007391	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
866768007392	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768007393	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
866768007394	substrate binding site [chemical binding]; other site
866768007395	putative dimerization interface [polypeptide binding]; other site
866768007396	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
866768007397	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
866768007398	active site
866768007399	interdomain interaction site; other site
866768007400	putative metal-binding site [ion binding]; other site
866768007401	nucleotide binding site [chemical binding]; other site
866768007402	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
866768007403	domain I; other site
866768007404	DNA binding groove [nucleotide binding]
866768007405	phosphate binding site [ion binding]; other site
866768007406	domain II; other site
866768007407	domain III; other site
866768007408	nucleotide binding site [chemical binding]; other site
866768007409	catalytic site [active]
866768007410	domain IV; other site
866768007411	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
866768007412	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
866768007413	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
866768007414	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
866768007415	hypothetical protein; Provisional; Region: PRK11037
866768007416	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
866768007417	putative inner membrane peptidase; Provisional; Region: PRK11778
866768007418	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
866768007419	tandem repeat interface [polypeptide binding]; other site
866768007420	oligomer interface [polypeptide binding]; other site
866768007421	active site residues [active]
866768007422	putative oxoacyl-(acyl carrier protein) reductase; Provisional; Region: PRK08945
866768007423	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
866768007424	NADP binding site [chemical binding]; other site
866768007425	homodimer interface [polypeptide binding]; other site
866768007426	active site
866768007427	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
866768007428	Cob(I)alamin adenosyltransferase N terminal; Region: Co_AT_N; pfam12557
866768007429	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
866768007430	homodimer interface [polypeptide binding]; other site
866768007431	Walker A motif; other site
866768007432	ATP binding site [chemical binding]; other site
866768007433	hydroxycobalamin binding site [chemical binding]; other site
866768007434	Walker B motif; other site
866768007435	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
866768007436	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
866768007437	RNA binding surface [nucleotide binding]; other site
866768007438	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
866768007439	probable active site [active]
866768007440	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
866768007441	hypothetical protein; Provisional; Region: PRK11630
866768007442	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
866768007443	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
866768007444	active site
866768007445	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
866768007446	anthranilate synthase component I; Provisional; Region: PRK13564
866768007447	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
866768007448	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
866768007449	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK09522
866768007450	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
866768007451	glutamine binding [chemical binding]; other site
866768007452	catalytic triad [active]
866768007453	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
866768007454	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
866768007455	bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Provisional; Region: PRK09427
866768007456	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
866768007457	active site
866768007458	ribulose/triose binding site [chemical binding]; other site
866768007459	phosphate binding site [ion binding]; other site
866768007460	substrate (anthranilate) binding pocket [chemical binding]; other site
866768007461	product (indole) binding pocket [chemical binding]; other site
866768007462	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
866768007463	active site
866768007464	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
866768007465	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
866768007466	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768007467	catalytic residue [active]
866768007468	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
866768007469	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
866768007470	substrate binding site [chemical binding]; other site
866768007471	active site
866768007472	catalytic residues [active]
866768007473	heterodimer interface [polypeptide binding]; other site
866768007474	General stress protein [General function prediction only]; Region: GsiB; COG3729
866768007475	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
866768007476	dimerization interface [polypeptide binding]; other site
866768007477	metal binding site [ion binding]; metal-binding site
866768007478	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3685
866768007479	outer membrane protein W; Provisional; Region: PRK10959
866768007480	hypothetical protein; Provisional; Region: PRK02868
866768007481	intracellular septation protein A; Reviewed; Region: PRK00259
866768007482	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
866768007483	transport protein TonB; Provisional; Region: PRK10819
866768007484	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
866768007485	YciI-like protein; Reviewed; Region: PRK11370
866768007486	voltage-gated potassium channel; Provisional; Region: PRK10537
866768007487	Ion channel; Region: Ion_trans_2; pfam07885
866768007488	TrkA-N domain; Region: TrkA_N; pfam02254
866768007489	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
866768007490	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
866768007491	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
866768007492	putative active site [active]
866768007493	catalytic site [active]
866768007494	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
866768007495	putative active site [active]
866768007496	catalytic site [active]
866768007497	dsDNA-mimic protein; Reviewed; Region: PRK05094
866768007498	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
866768007499	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
866768007500	Walker A/P-loop; other site
866768007501	ATP binding site [chemical binding]; other site
866768007502	Q-loop/lid; other site
866768007503	ABC transporter signature motif; other site
866768007504	Walker B; other site
866768007505	D-loop; other site
866768007506	H-loop/switch region; other site
866768007507	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
866768007508	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
866768007509	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
866768007510	Walker A/P-loop; other site
866768007511	ATP binding site [chemical binding]; other site
866768007512	Q-loop/lid; other site
866768007513	ABC transporter signature motif; other site
866768007514	Walker B; other site
866768007515	D-loop; other site
866768007516	H-loop/switch region; other site
866768007517	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
866768007518	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
866768007519	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
866768007520	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768007521	dimer interface [polypeptide binding]; other site
866768007522	conserved gate region; other site
866768007523	putative PBP binding loops; other site
866768007524	ABC-ATPase subunit interface; other site
866768007525	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
866768007526	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768007527	dimer interface [polypeptide binding]; other site
866768007528	conserved gate region; other site
866768007529	putative PBP binding loops; other site
866768007530	ABC-ATPase subunit interface; other site
866768007531	oligopeptide ABC transporter substrate-binding protein OppA; Provisional; Region: PRK15104
866768007532	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
866768007533	peptide binding site [polypeptide binding]; other site
866768007534	hypothetical protein; Provisional; Region: PRK11111
866768007535	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
866768007536	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
866768007537	putative catalytic cysteine [active]
866768007538	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
866768007539	putative active site [active]
866768007540	metal binding site [ion binding]; metal-binding site
866768007541	thymidine kinase; Provisional; Region: PRK04296
866768007542	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
866768007543	Domain in histone-like proteins of HNS family; Region: HNS; smart00528
866768007544	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
866768007545	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
866768007546	active site
866768007547	tetramer interface; other site
866768007548	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768007549	active site
866768007550	response regulator of RpoS; Provisional; Region: PRK10693
866768007551	phosphorylation site [posttranslational modification]
866768007552	intermolecular recognition site; other site
866768007553	dimerization interface [polypeptide binding]; other site
866768007554	hypothetical protein; Provisional; Region: PRK10279
866768007555	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
866768007556	active site
866768007557	nucleophile elbow; other site
866768007558	SEC-C motif; Region: SEC-C; pfam02810
866768007559	hypothetical protein; Provisional; Region: PRK04233
866768007560	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
866768007561	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
866768007562	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
866768007563	putative active site [active]
866768007564	putative substrate binding site [chemical binding]; other site
866768007565	putative cosubstrate binding site; other site
866768007566	catalytic site [active]
866768007567	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
866768007568	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
866768007569	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
866768007570	4Fe-4S binding domain; Region: Fer4; cl02805
866768007571	respiratory nitrate reductase, alpha subunit; Region: narG; TIGR01580
866768007572	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
866768007573	[4Fe-4S] binding site [ion binding]; other site
866768007574	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
866768007575	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
866768007576	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
866768007577	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
866768007578	molybdopterin cofactor binding site; other site
866768007579	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
866768007580	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
866768007581	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
866768007582	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
866768007583	dimerization interface [polypeptide binding]; other site
866768007584	Histidine kinase; Region: HisKA_3; pfam07730
866768007585	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866768007586	ATP binding site [chemical binding]; other site
866768007587	Mg2+ binding site [ion binding]; other site
866768007588	G-X-G motif; other site
866768007589	transcriptional regulator NarL; Provisional; Region: PRK10651
866768007590	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768007591	active site
866768007592	phosphorylation site [posttranslational modification]
866768007593	intermolecular recognition site; other site
866768007594	dimerization interface [polypeptide binding]; other site
866768007595	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
866768007596	DNA binding residues [nucleotide binding]
866768007597	dimerization interface [polypeptide binding]; other site
866768007598	putative invasin; Provisional; Region: PRK10177
866768007599	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
866768007600	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
866768007601	Uncharacterized protein involved in cation transport [Inorganic ion transport and metabolism]; Region: ChaC; COG3703
866768007602	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
866768007603	putative active site pocket [active]
866768007604	dimerization interface [polypeptide binding]; other site
866768007605	putative catalytic residue [active]
866768007606	cation transport regulator; Reviewed; Region: chaB; PRK09582
866768007607	calcium/sodium:proton antiporter; Provisional; Region: PRK10599
866768007608	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
866768007609	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
866768007610	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
866768007611	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
866768007612	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
866768007613	hypothetical protein; Provisional; Region: PRK10941
866768007614	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
866768007615	hypothetical protein; Provisional; Region: PRK10278
866768007616	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
866768007617	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768007618	peptide chain release factor 1; Validated; Region: prfA; PRK00591
866768007619	This domain is found in peptide chain release factors; Region: PCRF; smart00937
866768007620	RF-1 domain; Region: RF-1; pfam00472
866768007621	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
866768007622	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
866768007623	tRNA; other site
866768007624	putative tRNA binding site [nucleotide binding]; other site
866768007625	putative NADP binding site [chemical binding]; other site
866768007626	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
866768007627	outer membrane lipoprotein LolB; Region: lolB; TIGR00548
866768007628	Outer membrane lipoprotein LolB; Region: LolB; pfam03550
866768007629	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
866768007630	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
866768007631	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
866768007632	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
866768007633	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
866768007634	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
866768007635	active site
866768007636	putative transporter; Provisional; Region: PRK11660
866768007637	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
866768007638	Sulfate transporter family; Region: Sulfate_transp; pfam00916
866768007639	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
866768007640	hypothetical protein; Provisional; Region: PRK10692
866768007641	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
866768007642	putative active site [active]
866768007643	catalytic residue [active]
866768007644	GTP-binding protein YchF; Reviewed; Region: PRK09601
866768007645	YchF GTPase; Region: YchF; cd01900
866768007646	G1 box; other site
866768007647	GTP/Mg2+ binding site [chemical binding]; other site
866768007648	Switch I region; other site
866768007649	G2 box; other site
866768007650	Switch II region; other site
866768007651	G3 box; other site
866768007652	G4 box; other site
866768007653	G5 box; other site
866768007654	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
866768007655	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
866768007656	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
866768007657	Autotransporter beta-domain; Region: Autotransporter; pfam03797
866768007658	DNA-binding transcriptional regulator DhaR; Provisional; Region: PRK11388
866768007659	PAS domain; Region: PAS; smart00091
866768007660	putative active site [active]
866768007661	heme pocket [chemical binding]; other site
866768007662	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866768007663	Walker A motif; other site
866768007664	ATP binding site [chemical binding]; other site
866768007665	Walker B motif; other site
866768007666	arginine finger; other site
866768007667	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
866768007668	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK11468
866768007669	Dak1 domain; Region: Dak1; pfam02733
866768007670	dihydroxyacetone kinase subunit DhaL; Provisional; Region: PRK10005
866768007671	dihydroxyacetone kinase subunit M; Provisional; Region: PRK11377
866768007672	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3412
866768007673	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
866768007674	dimerization domain swap beta strand [polypeptide binding]; other site
866768007675	regulatory protein interface [polypeptide binding]; other site
866768007676	active site
866768007677	regulatory phosphorylation site [posttranslational modification]; other site
866768007678	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
866768007679	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
866768007680	trehalase; Provisional; Region: treA; PRK13271
866768007681	Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626
866768007682	hypothetical protein; Provisional; Region: PRK10457
866768007683	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
866768007684	Flagellar regulator YcgR; Region: YcgR; pfam07317
866768007685	PilZ domain; Region: PilZ; pfam07238
866768007686	lytic murein endotransglycosylase E; Provisional; Region: emtA; PRK15470
866768007687	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
866768007688	N-acetyl-D-glucosamine binding site [chemical binding]; other site
866768007689	catalytic residue [active]
866768007690	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
866768007691	dimer interface [polypeptide binding]; other site
866768007692	catalytic triad [active]
866768007693	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
866768007694	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
866768007695	TrkA-C domain; Region: TrkA_C; pfam02080
866768007696	Transporter associated domain; Region: CorC_HlyC; smart01091
866768007697	alanine racemase; Reviewed; Region: dadX; PRK03646
866768007698	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
866768007699	active site
866768007700	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
866768007701	substrate binding site [chemical binding]; other site
866768007702	catalytic residues [active]
866768007703	dimer interface [polypeptide binding]; other site
866768007704	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
866768007705	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
866768007706	SpoVR family protein; Provisional; Region: PRK11767
866768007707	Uncharacterized conserved protein [Function unknown]; Region: SpoVR; COG2719
866768007708	fatty acid metabolism regulator; Provisional; Region: PRK04984
866768007709	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
866768007710	DNA-binding site [nucleotide binding]; DNA binding site
866768007711	FadR C-terminal domain; Region: FadR_C; pfam07840
866768007712	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
866768007713	transmembrane helices; other site
866768007714	disulfide bond formation protein B; Provisional; Region: PRK01749
866768007715	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
866768007716	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
866768007717	active site
866768007718	DNA binding site [nucleotide binding]
866768007719	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
866768007720	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
866768007721	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
866768007722	Catalytic site [active]
866768007723	hypothetical protein; Provisional; Region: PRK05170
866768007724	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
866768007725	hypothetical protein; Provisional; Region: PRK10691
866768007726	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
866768007727	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
866768007728	Fels-1 Prophage Protein-like; Region: Fels1; pfam05666
866768007729	Fels-1 Prophage Protein-like; Region: Fels1; pfam05666
866768007730	septum formation inhibitor; Reviewed; Region: minC; PRK03511
866768007731	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
866768007732	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
866768007733	cell division inhibitor MinD; Provisional; Region: PRK10818
866768007734	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
866768007735	Switch I; other site
866768007736	Switch II; other site
866768007737	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
866768007738	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
866768007739	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
866768007740	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
866768007741	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
866768007742	Sensors of blue-light using FAD; Region: BLUF; smart01034
866768007743	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
866768007744	transcriptional regulator MirA; Provisional; Region: PRK15043
866768007745	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
866768007746	DNA binding residues [nucleotide binding]
866768007747	Protein of unknown function (DUF1398); Region: DUF1398; pfam07166
866768007748	anti-adapter protein IraM; Provisional; Region: PRK09919
866768007749	isocitrate dehydrogenase; Validated; Region: PRK07362
866768007750	isocitrate dehydrogenase; Reviewed; Region: PRK07006
866768007751	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
866768007752	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
866768007753	probable active site [active]
866768007754	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
866768007755	nudix motif; other site
866768007756	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
866768007757	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
866768007758	putative lysogenization regulator; Reviewed; Region: PRK00218
866768007759	adenylosuccinate lyase; Provisional; Region: PRK09285
866768007760	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
866768007761	tetramer interface [polypeptide binding]; other site
866768007762	active site
866768007763	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
866768007764	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768007765	active site
866768007766	phosphorylation site [posttranslational modification]
866768007767	intermolecular recognition site; other site
866768007768	dimerization interface [polypeptide binding]; other site
866768007769	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
866768007770	DNA binding site [nucleotide binding]
866768007771	sensor protein PhoQ; Provisional; Region: PRK10815
866768007772	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
866768007773	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
866768007774	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
866768007775	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866768007776	ATP binding site [chemical binding]; other site
866768007777	Mg2+ binding site [ion binding]; other site
866768007778	G-X-G motif; other site
866768007779	Uncharacterized conserved protein [Function unknown]; Region: COG2850
866768007780	Cupin-like domain; Region: Cupin_8; pfam13621
866768007781	Di- and tripeptidases [Amino acid transport and metabolism]; Region: PepD; COG2195
866768007782	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
866768007783	metal binding site [ion binding]; metal-binding site
866768007784	dimer interface [polypeptide binding]; other site
866768007785	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
866768007786	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866768007787	Walker A/P-loop; other site
866768007788	ATP binding site [chemical binding]; other site
866768007789	Q-loop/lid; other site
866768007790	ABC transporter signature motif; other site
866768007791	Walker B; other site
866768007792	D-loop; other site
866768007793	H-loop/switch region; other site
866768007794	TOBE domain; Region: TOBE_2; pfam08402
866768007795	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
866768007796	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768007797	dimer interface [polypeptide binding]; other site
866768007798	conserved gate region; other site
866768007799	putative PBP binding loops; other site
866768007800	ABC-ATPase subunit interface; other site
866768007801	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
866768007802	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768007803	dimer interface [polypeptide binding]; other site
866768007804	conserved gate region; other site
866768007805	putative PBP binding loops; other site
866768007806	ABC-ATPase subunit interface; other site
866768007807	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
866768007808	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
866768007809	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
866768007810	Repair protein; Region: Repair_PSII; cl01535
866768007811	NAD-dependent deacetylase; Provisional; Region: PRK00481
866768007812	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
866768007813	NAD+ binding site [chemical binding]; other site
866768007814	substrate binding site [chemical binding]; other site
866768007815	Zn binding site [ion binding]; other site
866768007816	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
866768007817	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
866768007818	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
866768007819	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
866768007820	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
866768007821	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
866768007822	FtsX-like permease family; Region: FtsX; pfam02687
866768007823	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
866768007824	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
866768007825	Walker A/P-loop; other site
866768007826	ATP binding site [chemical binding]; other site
866768007827	Q-loop/lid; other site
866768007828	ABC transporter signature motif; other site
866768007829	Walker B; other site
866768007830	D-loop; other site
866768007831	H-loop/switch region; other site
866768007832	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
866768007833	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
866768007834	FtsX-like permease family; Region: FtsX; pfam02687
866768007835	Predicted membrane protein [Function unknown]; Region: COG4763
866768007836	Acyltransferase family; Region: Acyl_transf_3; pfam01757
866768007837	transcription-repair coupling factor; Provisional; Region: PRK10689
866768007838	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
866768007839	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
866768007840	ATP binding site [chemical binding]; other site
866768007841	putative Mg++ binding site [ion binding]; other site
866768007842	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
866768007843	nucleotide binding region [chemical binding]; other site
866768007844	ATP-binding site [chemical binding]; other site
866768007845	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
866768007846	L,D-transpeptidase; Provisional; Region: PRK10260
866768007847	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
866768007848	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
866768007849	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
866768007850	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
866768007851	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
866768007852	hypothetical protein; Provisional; Region: PRK11280
866768007853	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
866768007854	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
866768007855	hypothetical protein; Provisional; Region: PRK04940
866768007856	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
866768007857	beta-hexosaminidase; Provisional; Region: PRK05337
866768007858	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
866768007859	thiamine kinase; Region: ycfN_thiK; TIGR02721
866768007860	active site
866768007861	substrate binding site [chemical binding]; other site
866768007862	ATP binding site [chemical binding]; other site
866768007863	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
866768007864	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
866768007865	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
866768007866	putative dimer interface [polypeptide binding]; other site
866768007867	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
866768007868	nucleotide binding site/active site [active]
866768007869	HIT family signature motif; other site
866768007870	catalytic residue [active]
866768007871	ferric-rhodotorulic acid outer membrane transporter; Provisional; Region: PRK10003
866768007872	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
866768007873	N-terminal plug; other site
866768007874	ligand-binding site [chemical binding]; other site
866768007875	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
866768007876	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
866768007877	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
866768007878	active site turn [active]
866768007879	phosphorylation site [posttranslational modification]
866768007880	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
866768007881	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
866768007882	active site
866768007883	DNA polymerase III subunit delta'; Validated; Region: PRK07993
866768007884	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
866768007885	thymidylate kinase; Validated; Region: tmk; PRK00698
866768007886	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
866768007887	TMP-binding site; other site
866768007888	ATP-binding site [chemical binding]; other site
866768007889	conserved hypothetical protein, YceG family; Region: TIGR00247
866768007890	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
866768007891	dimerization interface [polypeptide binding]; other site
866768007892	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
866768007893	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
866768007894	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768007895	catalytic residue [active]
866768007896	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
866768007897	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
866768007898	dimer interface [polypeptide binding]; other site
866768007899	active site
866768007900	acyl carrier protein; Provisional; Region: acpP; PRK00982
866768007901	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
866768007902	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
866768007903	NAD(P) binding site [chemical binding]; other site
866768007904	homotetramer interface [polypeptide binding]; other site
866768007905	homodimer interface [polypeptide binding]; other site
866768007906	active site
866768007907	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
866768007908	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
866768007909	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
866768007910	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
866768007911	dimer interface [polypeptide binding]; other site
866768007912	active site
866768007913	CoA binding pocket [chemical binding]; other site
866768007914	putative phosphate acyltransferase; Provisional; Region: PRK05331
866768007915	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
866768007916	hypothetical protein; Provisional; Region: PRK11193
866768007917	Maf-like protein; Region: Maf; pfam02545
866768007918	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
866768007919	active site
866768007920	dimer interface [polypeptide binding]; other site
866768007921	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
866768007922	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
866768007923	RNA binding surface [nucleotide binding]; other site
866768007924	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
866768007925	active site
866768007926	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
866768007927	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
866768007928	homodimer interface [polypeptide binding]; other site
866768007929	oligonucleotide binding site [chemical binding]; other site
866768007930	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
866768007931	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
866768007932	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
866768007933	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
866768007934	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
866768007935	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
866768007936	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
866768007937	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
866768007938	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
866768007939	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
866768007940	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
866768007941	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
866768007942	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
866768007943	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
866768007944	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
866768007945	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
866768007946	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgF; COG4787
866768007947	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
866768007948	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
866768007949	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
866768007950	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
866768007951	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
866768007952	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
866768007953	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06655
866768007954	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
866768007955	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
866768007956	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
866768007957	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
866768007958	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
866768007959	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
866768007960	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
866768007961	Flagellar basal body P-ring biosynthesis protein [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: FlgA; COG1261
866768007962	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
866768007963	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
866768007964	anti-sigma28 factor FlgM; Provisional; Region: PRK10810
866768007965	flagella synthesis chaperone protein FlgN; Provisional; Region: PRK15459
866768007966	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
866768007967	MviN-like protein; Region: MVIN; pfam03023
866768007968	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
866768007969	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
866768007970	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
866768007971	hypothetical protein; Provisional; Region: PRK11239
866768007972	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3132
866768007973	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
866768007974	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
866768007975	multidrug resistance protein MdtH; Provisional; Region: PRK11646
866768007976	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768007977	putative substrate translocation pore; other site
866768007978	glutaredoxin 2; Provisional; Region: PRK10387
866768007979	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
866768007980	C-terminal domain interface [polypeptide binding]; other site
866768007981	GSH binding site (G-site) [chemical binding]; other site
866768007982	catalytic residues [active]
866768007983	putative dimer interface [polypeptide binding]; other site
866768007984	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
866768007985	N-terminal domain interface [polypeptide binding]; other site
866768007986	lipoprotein; Provisional; Region: PRK10598
866768007987	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
866768007988	active site
866768007989	substrate binding pocket [chemical binding]; other site
866768007990	dimer interface [polypeptide binding]; other site
866768007991	DNA damage-inducible protein I; Provisional; Region: PRK10597
866768007992	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
866768007993	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
866768007994	hydroxyglutarate oxidase; Provisional; Region: PRK11728
866768007995	Protein of unknown function (DUF2770); Region: DUF2770; pfam10968
866768007996	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
866768007997	hypothetical protein; Provisional; Region: PRK03757
866768007998	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
866768007999	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
866768008000	active site residue [active]
866768008001	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
866768008002	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
866768008003	putative acyl-acceptor binding pocket; other site
866768008004	drug efflux system protein MdtG; Provisional; Region: PRK09874
866768008005	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768008006	putative substrate translocation pore; other site
866768008007	secY/secA suppressor protein; Provisional; Region: PRK11467
866768008008	lipoprotein; Provisional; Region: PRK10175
866768008009	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
866768008010	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
866768008011	Ligand binding site; other site
866768008012	DXD motif; other site
866768008013	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
866768008014	Periplasmic glucan biosynthesis protein, MdoG; Region: MdoG; pfam04349
866768008015	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
866768008016	Acyltransferase family; Region: Acyl_transf_3; pfam01757
866768008017	Phosphatidylserine/phosphatidylglycerophosphate/car diolipin synthases and related enzymes [Lipid metabolism]; Region: Cls; COG1502
866768008018	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
866768008019	putative active site [active]
866768008020	catalytic site [active]
866768008021	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
866768008022	putative active site [active]
866768008023	catalytic site [active]
866768008024	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
866768008025	putative ADP-ribose binding site [chemical binding]; other site
866768008026	putative active site [active]
866768008027	Fimbrial protein; Region: Fimbrial; cl01416
866768008028	curli assembly protein CsgC; Provisional; Region: csgC; PRK10102
866768008029	major curlin subunit; Provisional; Region: csgA; PRK10051
866768008030	Curlin associated repeat; Region: Curlin_rpt; pfam07012
866768008031	Curlin associated repeat; Region: Curlin_rpt; pfam07012
866768008032	curlin minor subunit CsgB; Provisional; Region: csgB; PRK10101
866768008033	Curlin associated repeat; Region: Curlin_rpt; pfam07012
866768008034	Curlin associated repeat; Region: Curlin_rpt; pfam07012
866768008035	DNA-binding transcriptional regulator CsgD; Provisional; Region: PRK10100
866768008036	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
866768008037	DNA binding residues [nucleotide binding]
866768008038	dimerization interface [polypeptide binding]; other site
866768008039	curli assembly protein CsgE; Provisional; Region: PRK10386
866768008040	curli assembly protein CsgF; Provisional; Region: PRK10050
866768008041	curli production assembly/transport protein CsgG; Provisional; Region: PRK15184
866768008042	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
866768008043	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
866768008044	putative hydrolase; Validated; Region: PRK09248
866768008045	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
866768008046	active site
866768008047	bifunctional glyoxylate/hydroxypyruvate reductase A; Provisional; Region: ghrA; PRK15469
866768008048	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
866768008049	putative ligand binding site [chemical binding]; other site
866768008050	NAD binding site [chemical binding]; other site
866768008051	dimerization interface [polypeptide binding]; other site
866768008052	catalytic site [active]
866768008053	Transposase; Region: HTH_Tnp_1; cl17663
866768008054	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
866768008055	putative transposase OrfB; Reviewed; Region: PHA02517
866768008056	HTH-like domain; Region: HTH_21; pfam13276
866768008057	Integrase core domain; Region: rve; pfam00665
866768008058	Integrase core domain; Region: rve_2; pfam13333
866768008059	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
866768008060	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
866768008061	metal binding site [ion binding]; metal-binding site
866768008062	active site
866768008063	I-site; other site
866768008064	outer membrane protein PgaA; Provisional; Region: pgaA; PRK10049
866768008065	outer membrane N-deacetylase; Provisional; Region: pgaB; PRK14582
866768008066	N-terminal putative catalytic polysaccharide deacetylase domain of bacterial poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB, and similar proteins; Region: CE4_PgaB_5s; cd10964
866768008067	putative active site [active]
866768008068	putative metal binding site [ion binding]; other site
866768008069	N-glycosyltransferase; Provisional; Region: PRK11204
866768008070	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
866768008071	DXD motif; other site
866768008072	Glycosyl transferase family group 2; Region: Glyco_trans_2_3; pfam13632
866768008073	putative PGA biosynthesis protein; Provisional; Region: pgaD; PRK14585
866768008074	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
866768008075	hypothetical protein; Provisional; Region: PRK10536
866768008076	Tat-translocated enzyme; Region: tat_substr_1; TIGR01412
866768008077	Predicted iron-dependent peroxidase [Inorganic ion transport and metabolism]; Region: COG2837
866768008078	inactive ferrous ion transporter periplasmic protein EfeO; Provisional; Region: PRK10378
866768008079	Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473
866768008080	Imelysin; Region: Peptidase_M75; pfam09375
866768008081	FTR1 family protein; Region: TIGR00145
866768008082	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
866768008083	Na binding site [ion binding]; other site
866768008084	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
866768008085	Predicted transcriptional regulator [Transcription]; Region: COG3905
866768008086	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
866768008087	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
866768008088	Glutamate binding site [chemical binding]; other site
866768008089	NAD binding site [chemical binding]; other site
866768008090	catalytic residues [active]
866768008091	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
866768008092	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
866768008093	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
866768008094	pyrimidine utilization protein A; Region: RutA; TIGR03612
866768008095	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
866768008096	active site
866768008097	dimer interface [polypeptide binding]; other site
866768008098	non-prolyl cis peptide bond; other site
866768008099	insertion regions; other site
866768008100	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
866768008101	Isochorismatase family; Region: Isochorismatase; pfam00857
866768008102	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
866768008103	catalytic triad [active]
866768008104	conserved cis-peptide bond; other site
866768008105	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
866768008106	homotrimer interaction site [polypeptide binding]; other site
866768008107	putative active site [active]
866768008108	pyrimidine utilization protein D; Region: RutD; TIGR03611
866768008109	Nitroreductase-like family 5.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_5; cd02148
866768008110	putative FMN binding site [chemical binding]; other site
866768008111	pyrimidine utilization flavin reductase protein F; Region: RutF; TIGR03615
866768008112	pyrimidine utilization transport protein G; Region: RutG; TIGR03616
866768008113	General stress protein [General function prediction only]; Region: GsiB; COG3729
866768008114	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
866768008115	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
866768008116	hypothetical protein; Provisional; Region: PRK10174
866768008117	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
866768008118	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
866768008119	catalytic core [active]
866768008120	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
866768008121	hypothetical protein; Provisional; Region: PRK09784
866768008122	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
866768008123	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
866768008124	HSP70 interaction site [polypeptide binding]; other site
866768008125	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
866768008126	substrate binding site [polypeptide binding]; other site
866768008127	dimer interface [polypeptide binding]; other site
866768008128	chaperone-modulator protein CbpM; Provisional; Region: PRK10265
866768008129	MerR HTH family regulatory protein; Region: MerR_2; pfam13591
866768008130	chaperone protein TorD; Validated; Region: torD; PRK04976
866768008131	trimethylamine N-oxide reductase I catalytic subunit; Provisional; Region: PRK15102
866768008132	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
866768008133	molybdopterin cofactor binding site [chemical binding]; other site
866768008134	substrate binding site [chemical binding]; other site
866768008135	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
866768008136	molybdopterin cofactor binding site; other site
866768008137	trimethylamine N-oxide reductase cytochrome c-type subunit; Provisional; Region: PRK15032
866768008138	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
866768008139	DNA-binding transcriptional regulator TorR; Provisional; Region: PRK10766
866768008140	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768008141	active site
866768008142	phosphorylation site [posttranslational modification]
866768008143	intermolecular recognition site; other site
866768008144	dimerization interface [polypeptide binding]; other site
866768008145	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
866768008146	DNA binding site [nucleotide binding]
866768008147	TMAO reductase system periplasmic protein TorT; Provisional; Region: PRK10936
866768008148	TorT-like proteins, a periplasmic binding protein family that activates induction of the Tor respiratory system upon trimethylamine N-oxide (TMAO) electron-acceptor binding in bacteria; Region: PBP1_TorT-like; cd06306
866768008149	putative ligand binding site [chemical binding]; other site
866768008150	hybrid sensory histidine kinase TorS; Provisional; Region: PRK11466
866768008151	HAMP domain; Region: HAMP; pfam00672
866768008152	dimerization interface [polypeptide binding]; other site
866768008153	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
866768008154	dimer interface [polypeptide binding]; other site
866768008155	phosphorylation site [posttranslational modification]
866768008156	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866768008157	ATP binding site [chemical binding]; other site
866768008158	Mg2+ binding site [ion binding]; other site
866768008159	G-X-G motif; other site
866768008160	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768008161	active site
866768008162	phosphorylation site [posttranslational modification]
866768008163	intermolecular recognition site; other site
866768008164	dimerization interface [polypeptide binding]; other site
866768008165	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
866768008166	putative binding surface; other site
866768008167	active site
866768008168	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
866768008169	4Fe-4S binding domain; Region: Fer4_5; pfam12801
866768008170	4Fe-4S binding domain; Region: Fer4_5; pfam12801
866768008171	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
866768008172	GnsA/GnsB family; Region: GnsAB; pfam08178
866768008173	cold shock gene; Provisional; Region: PRK09891
866768008174	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
866768008175	DNA-binding site [nucleotide binding]; DNA binding site
866768008176	RNA-binding motif; other site
866768008177	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
866768008178	DNA-binding site [nucleotide binding]; DNA binding site
866768008179	RNA-binding motif; other site
866768008180	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
866768008181	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
866768008182	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
866768008183	polysaccharide export protein Wza; Provisional; Region: PRK15078
866768008184	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
866768008185	SLBB domain; Region: SLBB; pfam10531
866768008186	SLBB domain; Region: SLBB; pfam10531
866768008187	Low molecular weight phosphatase family; Region: LMWPc; cd00115
866768008188	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
866768008189	active site
866768008190	cryptic autophosphorylating protein tyrosine kinase Etk; Provisional; Region: PRK09841
866768008191	Chain length determinant protein; Region: Wzz; pfam02706
866768008192	Chain length determinant protein; Region: Wzz; cl15801
866768008193	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
866768008194	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
866768008195	Nucleotide binding site [chemical binding]; other site
866768008196	glucose-1-phosphatase/inositol phosphatase; Provisional; Region: PRK10173
866768008197	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
866768008198	catalytic core [active]
866768008199	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
866768008200	Membrane bound YbgT-like protein; Region: YbgT_YccB; cl02039
866768008201	cytochrome bd-II oxidase subunit 2; Provisional; Region: PRK15028
866768008202	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
866768008203	cytochrome bd-II oxidase subunit 1; Provisional; Region: PRK15035
866768008204	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
866768008205	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
866768008206	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
866768008207	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
866768008208	putative substrate-binding site; other site
866768008209	nickel binding site [ion binding]; other site
866768008210	hydrogenase 1 b-type cytochrome subunit; Provisional; Region: PRK10171
866768008211	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
866768008212	hydrogenase 1 large subunit; Provisional; Region: PRK10170
866768008213	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
866768008214	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
866768008215	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
866768008216	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
866768008217	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
866768008218	YccA-like proteins; Region: YccA_like; cd10433
866768008219	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
866768008220	sulfur transfer protein TusE; Provisional; Region: PRK11508
866768008221	Acylphosphatase; Region: Acylphosphatase; cl00551
866768008222	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
866768008223	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
866768008224	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
866768008225	putative RNA binding site [nucleotide binding]; other site
866768008226	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768008227	S-adenosylmethionine binding site [chemical binding]; other site
866768008228	heat shock protein HspQ; Provisional; Region: PRK14129
866768008229	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
866768008230	hypothetical protein; Provisional; Region: PRK03641
866768008231	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3110
866768008232	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
866768008233	active site
866768008234	dimer interfaces [polypeptide binding]; other site
866768008235	catalytic residues [active]
866768008236	DNA helicase IV; Provisional; Region: helD; PRK11054
866768008237	DNA helicase IV / RNA helicase N terminal; Region: Nucleolin_N; pfam12462
866768008238	Part of AAA domain; Region: AAA_19; pfam13245
866768008239	Family description; Region: UvrD_C_2; pfam13538
866768008240	Predicted membrane protein [Function unknown]; Region: COG3304
866768008241	Domain of unknown function (DUF307); Region: DUF307; pfam03733
866768008242	Domain of unknown function (DUF307); Region: DUF307; pfam03733
866768008243	TIGR01666 family membrane protein; Region: YCCS
866768008244	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
866768008245	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
866768008246	Regulator of competence-specific genes [Transcription]; Region: TfoX; COG3070
866768008247	TfoX C-terminal domain; Region: TfoX_C; pfam04994
866768008248	cell division inhibitor SulA; Region: sula; TIGR00623
866768008249	outer membrane protein A; Reviewed; Region: PRK10808
866768008250	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
866768008251	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
866768008252	ligand binding site [chemical binding]; other site
866768008253	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
866768008254	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
866768008255	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
866768008256	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
866768008257	active site 1 [active]
866768008258	dimer interface [polypeptide binding]; other site
866768008259	active site 2 [active]
866768008260	ribosome modulation factor; Provisional; Region: PRK14563
866768008261	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
866768008262	Protein of unknown function (DUF330); Region: DUF330; pfam03886
866768008263	paraquat-inducible protein B; Provisional; Region: PRK10807
866768008264	mce related protein; Region: MCE; pfam02470
866768008265	mce related protein; Region: MCE; pfam02470
866768008266	mce related protein; Region: MCE; pfam02470
866768008267	DASH complex subunit Duo1; Region: DASH_Duo1; pfam08651
866768008268	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
866768008269	Paraquat-inducible protein A; Region: PqiA; pfam04403
866768008270	Paraquat-inducible protein A; Region: PqiA; pfam04403
866768008271	ABC transporter ATPase component; Reviewed; Region: PRK11147
866768008272	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866768008273	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866768008274	Walker A/P-loop; other site
866768008275	Walker A/P-loop; other site
866768008276	ATP binding site [chemical binding]; other site
866768008277	ATP binding site [chemical binding]; other site
866768008278	Q-loop/lid; other site
866768008279	Q-loop/lid; other site
866768008280	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
866768008281	ABC transporter signature motif; other site
866768008282	Walker B; other site
866768008283	D-loop; other site
866768008284	ABC transporter; Region: ABC_tran_2; pfam12848
866768008285	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
866768008286	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
866768008287	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
866768008288	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
866768008289	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768008290	S-adenosylmethionine binding site [chemical binding]; other site
866768008291	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
866768008292	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
866768008293	MOSC domain; Region: MOSC; pfam03473
866768008294	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
866768008295	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
866768008296	catalytic loop [active]
866768008297	iron binding site [ion binding]; other site
866768008298	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
866768008299	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
866768008300	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
866768008301	quinone interaction residues [chemical binding]; other site
866768008302	active site
866768008303	catalytic residues [active]
866768008304	FMN binding site [chemical binding]; other site
866768008305	substrate binding site [chemical binding]; other site
866768008306	putativi pili assembly chaperone; Provisional; Region: PRK11385
866768008307	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
866768008308	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
866768008309	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
866768008310	Fimbrial protein; Region: Fimbrial; cl01416
866768008311	Fimbrial protein; Region: Fimbrial; cl01416
866768008312	outer membrane usher protein; Provisional; Region: PRK15193
866768008313	PapC N-terminal domain; Region: PapC_N; pfam13954
866768008314	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
866768008315	PapC C-terminal domain; Region: PapC_C; pfam13953
866768008316	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
866768008317	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
866768008318	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
866768008319	Fimbrial protein; Region: Fimbrial; cl01416
866768008320	NAD(P)H-dependent FMN reductase; Provisional; Region: PRK10569
866768008321	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
866768008322	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
866768008323	substrate binding pocket [chemical binding]; other site
866768008324	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
866768008325	membrane-bound complex binding site; other site
866768008326	hinge residues; other site
866768008327	alkanesulfonate monooxygenase; Provisional; Region: PRK00719
866768008328	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
866768008329	active site
866768008330	dimer interface [polypeptide binding]; other site
866768008331	non-prolyl cis peptide bond; other site
866768008332	insertion regions; other site
866768008333	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
866768008334	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768008335	dimer interface [polypeptide binding]; other site
866768008336	conserved gate region; other site
866768008337	putative PBP binding loops; other site
866768008338	ABC-ATPase subunit interface; other site
866768008339	aliphatic sulfonates transport ATP-binding subunit; Provisional; Region: ssuB; PRK11247
866768008340	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
866768008341	Walker A/P-loop; other site
866768008342	ATP binding site [chemical binding]; other site
866768008343	Q-loop/lid; other site
866768008344	ABC transporter signature motif; other site
866768008345	Walker B; other site
866768008346	D-loop; other site
866768008347	H-loop/switch region; other site
866768008348	aminopeptidase N; Provisional; Region: pepN; PRK14015
866768008349	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
866768008350	active site
866768008351	Zn binding site [ion binding]; other site
866768008352	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
866768008353	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
866768008354	active site
866768008355	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
866768008356	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
866768008357	putative dimer interface [polypeptide binding]; other site
866768008358	putative anticodon binding site; other site
866768008359	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
866768008360	homodimer interface [polypeptide binding]; other site
866768008361	motif 1; other site
866768008362	motif 2; other site
866768008363	active site
866768008364	motif 3; other site
866768008365	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
866768008366	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
866768008367	trimer interface [polypeptide binding]; other site
866768008368	eyelet of channel; other site
866768008369	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
866768008370	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
866768008371	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768008372	homodimer interface [polypeptide binding]; other site
866768008373	catalytic residue [active]
866768008374	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
866768008375	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
866768008376	Peptidase M15; Region: Peptidase_M15_3; cl01194
866768008377	murein L,D-transpeptidase; Provisional; Region: PRK10594
866768008378	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
866768008379	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
866768008380	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
866768008381	Uncharacterized protein involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: MukB; COG3096
866768008382	MukB N-terminal; Region: MukB; pfam04310
866768008383	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
866768008384	condesin subunit E; Provisional; Region: PRK05256
866768008385	condesin subunit F; Provisional; Region: PRK05260
866768008386	Methyltransferase domain; Region: Methyltransf_31; pfam13847
866768008387	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768008388	S-adenosylmethionine binding site [chemical binding]; other site
866768008389	Uncharacterized conserved protein [Function unknown]; Region: COG1434
866768008390	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
866768008391	putative active site [active]
866768008392	hypothetical protein; Provisional; Region: PRK10593
866768008393	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
866768008394	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
866768008395	Ligand binding site; other site
866768008396	oligomer interface; other site
866768008397	hypothetical protein; Provisional; Region: PRK11827
866768008398	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3214
866768008399	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
866768008400	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
866768008401	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
866768008402	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
866768008403	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
866768008404	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
866768008405	Walker A/P-loop; other site
866768008406	ATP binding site [chemical binding]; other site
866768008407	Q-loop/lid; other site
866768008408	ABC transporter signature motif; other site
866768008409	Walker B; other site
866768008410	D-loop; other site
866768008411	H-loop/switch region; other site
866768008412	ComEC family competence protein; Provisional; Region: PRK11539
866768008413	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
866768008414	ComEC/Rec2-related protein; Region: ComEC_N-term; TIGR00360
866768008415	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
866768008416	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
866768008417	IHF dimer interface [polypeptide binding]; other site
866768008418	IHF - DNA interface [nucleotide binding]; other site
866768008419	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
866768008420	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
866768008421	RNA binding site [nucleotide binding]; other site
866768008422	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
866768008423	RNA binding site [nucleotide binding]; other site
866768008424	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
866768008425	RNA binding site [nucleotide binding]; other site
866768008426	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
866768008427	RNA binding site [nucleotide binding]; other site
866768008428	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
866768008429	RNA binding site [nucleotide binding]; other site
866768008430	cytidylate kinase; Provisional; Region: cmk; PRK00023
866768008431	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
866768008432	CMP-binding site; other site
866768008433	The sites determining sugar specificity; other site
866768008434	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
866768008435	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
866768008436	Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine enolpyruvyl transferase. Both enzymes catalyze the reaction of enolpyruvyl transfer; Region: EPT-like; cd01554
866768008437	hinge; other site
866768008438	active site
866768008439	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
866768008440	homodimer interface [polypeptide binding]; other site
866768008441	substrate-cofactor binding pocket; other site
866768008442	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768008443	catalytic residue [active]
866768008444	Predicted membrane protein [Function unknown]; Region: COG2323
866768008445	uncharacterized domain; Region: TIGR00702
866768008446	YcaO-like family; Region: YcaO; pfam02624
866768008447	formate transporter; Provisional; Region: PRK10805
866768008448	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
866768008449	Pyruvate formate lyase 1; Region: PFL1; cd01678
866768008450	coenzyme A binding site [chemical binding]; other site
866768008451	active site
866768008452	catalytic residues [active]
866768008453	glycine loop; other site
866768008454	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
866768008455	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866768008456	FeS/SAM binding site; other site
866768008457	hypothetical protein; Provisional; Region: PRK09739
866768008458	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
866768008459	Transcriptional regulator [Transcription]; Region: LysR; COG0583
866768008460	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768008461	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
866768008462	putative effector binding pocket; other site
866768008463	putative dimerization interface [polypeptide binding]; other site
866768008464	Amino acid permease; Region: AA_permease_2; pfam13520
866768008465	putative MFS family transporter protein; Provisional; Region: PRK03633
866768008466	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768008467	putative substrate translocation pore; other site
866768008468	Isochorismatase family; Region: Isochorismatase; pfam00857
866768008469	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
866768008470	catalytic triad [active]
866768008471	dimer interface [polypeptide binding]; other site
866768008472	conserved cis-peptide bond; other site
866768008473	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
866768008474	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
866768008475	4Fe-4S binding domain; Region: Fer4; pfam00037
866768008476	anaerobic dimethyl sulfoxide reductase subunit A; Provisional; Region: PRK14990
866768008477	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
866768008478	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
866768008479	putative [Fe4-S4] binding site [ion binding]; other site
866768008480	putative molybdopterin cofactor binding site [chemical binding]; other site
866768008481	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
866768008482	putative molybdopterin cofactor binding site; other site
866768008483	seryl-tRNA synthetase; Provisional; Region: PRK05431
866768008484	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
866768008485	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
866768008486	dimer interface [polypeptide binding]; other site
866768008487	active site
866768008488	motif 1; other site
866768008489	motif 2; other site
866768008490	motif 3; other site
866768008491	recombination factor protein RarA; Reviewed; Region: PRK13342
866768008492	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866768008493	Walker A motif; other site
866768008494	ATP binding site [chemical binding]; other site
866768008495	Walker B motif; other site
866768008496	arginine finger; other site
866768008497	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
866768008498	periplasmic chaperone LolA; Region: lolA; TIGR00547
866768008499	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
866768008500	DNA translocase FtsK; Provisional; Region: PRK10263
866768008501	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
866768008502	DNA translocase FtsK; Provisional; Region: PRK10263
866768008503	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
866768008504	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
866768008505	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
866768008506	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
866768008507	putative DNA binding site [nucleotide binding]; other site
866768008508	putative Zn2+ binding site [ion binding]; other site
866768008509	AsnC family; Region: AsnC_trans_reg; pfam01037
866768008510	thioredoxin reductase; Provisional; Region: PRK10262
866768008511	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
866768008512	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
866768008513	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
866768008514	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
866768008515	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866768008516	Walker A/P-loop; other site
866768008517	ATP binding site [chemical binding]; other site
866768008518	Q-loop/lid; other site
866768008519	ABC transporter signature motif; other site
866768008520	Walker B; other site
866768008521	D-loop; other site
866768008522	H-loop/switch region; other site
866768008523	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
866768008524	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
866768008525	ATP-binding cassette domain of CydCD, subfamily C; Region: ABCC_cytochrome_bd; cd03247
866768008526	Walker A/P-loop; other site
866768008527	ATP binding site [chemical binding]; other site
866768008528	Q-loop/lid; other site
866768008529	ABC transporter signature motif; other site
866768008530	Walker B; other site
866768008531	D-loop; other site
866768008532	H-loop/switch region; other site
866768008533	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
866768008534	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
866768008535	rRNA binding site [nucleotide binding]; other site
866768008536	predicted 30S ribosome binding site; other site
866768008537	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
866768008538	Clp amino terminal domain; Region: Clp_N; pfam02861
866768008539	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866768008540	Walker A motif; other site
866768008541	ATP binding site [chemical binding]; other site
866768008542	Walker B motif; other site
866768008543	arginine finger; other site
866768008544	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866768008545	Walker A motif; other site
866768008546	ATP binding site [chemical binding]; other site
866768008547	Walker B motif; other site
866768008548	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
866768008549	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
866768008550	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
866768008551	DNA-binding site [nucleotide binding]; DNA binding site
866768008552	RNA-binding motif; other site
866768008553	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
866768008554	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
866768008555	Walker A/P-loop; other site
866768008556	ATP binding site [chemical binding]; other site
866768008557	Q-loop/lid; other site
866768008558	ABC transporter signature motif; other site
866768008559	Walker B; other site
866768008560	D-loop; other site
866768008561	H-loop/switch region; other site
866768008562	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
866768008563	FtsX-like permease family; Region: FtsX; pfam02687
866768008564	macrolide transporter subunit MacA; Provisional; Region: PRK11578
866768008565	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
866768008566	HlyD family secretion protein; Region: HlyD_3; pfam13437
866768008567	Protein of unknown function (DUF535); Region: DUF535; pfam04393
866768008568	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
866768008569	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
866768008570	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
866768008571	putative active site [active]
866768008572	putative metal-binding site [ion binding]; other site
866768008573	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
866768008574	amphipathic channel; other site
866768008575	Asn-Pro-Ala signature motifs; other site
866768008576	Predicted membrane protein [Function unknown]; Region: COG2431
866768008577	hybrid cluster protein; Provisional; Region: PRK05290
866768008578	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
866768008579	ACS interaction site; other site
866768008580	CODH interaction site; other site
866768008581	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
866768008582	hybrid metal cluster; other site
866768008583	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
866768008584	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
866768008585	FAD binding pocket [chemical binding]; other site
866768008586	FAD binding motif [chemical binding]; other site
866768008587	phosphate binding motif [ion binding]; other site
866768008588	beta-alpha-beta structure motif; other site
866768008589	NAD binding pocket [chemical binding]; other site
866768008590	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
866768008591	catalytic loop [active]
866768008592	iron binding site [ion binding]; other site
866768008593	pyruvate dehydrogenase; Provisional; Region: PRK09124
866768008594	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
866768008595	PYR/PP interface [polypeptide binding]; other site
866768008596	dimer interface [polypeptide binding]; other site
866768008597	tetramer interface [polypeptide binding]; other site
866768008598	TPP binding site [chemical binding]; other site
866768008599	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
866768008600	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
866768008601	TPP-binding site [chemical binding]; other site
866768008602	Threonine aldolase [Amino acid transport and metabolism]; Region: GLY1; COG2008
866768008603	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
866768008604	tetramer interface [polypeptide binding]; other site
866768008605	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768008606	catalytic residue [active]
866768008607	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
866768008608	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
866768008609	putative NAD(P) binding site [chemical binding]; other site
866768008610	putative active site [active]
866768008611	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
866768008612	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
866768008613	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
866768008614	NAD(P) binding site [chemical binding]; other site
866768008615	active site
866768008616	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
866768008617	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
866768008618	amidase catalytic site [active]
866768008619	Zn binding residues [ion binding]; other site
866768008620	substrate binding site [chemical binding]; other site
866768008621	hypothetical protein; Provisional; Region: PRK02877
866768008622	putative lipoprotein; Provisional; Region: PRK10533
866768008623	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
866768008624	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866768008625	Walker A/P-loop; other site
866768008626	ATP binding site [chemical binding]; other site
866768008627	Q-loop/lid; other site
866768008628	ABC transporter signature motif; other site
866768008629	Walker B; other site
866768008630	D-loop; other site
866768008631	H-loop/switch region; other site
866768008632	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
866768008633	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
866768008634	substrate binding pocket [chemical binding]; other site
866768008635	membrane-bound complex binding site; other site
866768008636	hinge residues; other site
866768008637	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
866768008638	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768008639	dimer interface [polypeptide binding]; other site
866768008640	conserved gate region; other site
866768008641	putative PBP binding loops; other site
866768008642	ABC-ATPase subunit interface; other site
866768008643	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768008644	dimer interface [polypeptide binding]; other site
866768008645	conserved gate region; other site
866768008646	putative PBP binding loops; other site
866768008647	ABC-ATPase subunit interface; other site
866768008648	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
866768008649	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
866768008650	substrate binding pocket [chemical binding]; other site
866768008651	membrane-bound complex binding site; other site
866768008652	hinge residues; other site
866768008653	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
866768008654	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768008655	S-adenosylmethionine binding site [chemical binding]; other site
866768008656	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
866768008657	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
866768008658	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768008659	dimer interface [polypeptide binding]; other site
866768008660	conserved gate region; other site
866768008661	putative PBP binding loops; other site
866768008662	ABC-ATPase subunit interface; other site
866768008663	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
866768008664	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768008665	dimer interface [polypeptide binding]; other site
866768008666	conserved gate region; other site
866768008667	putative PBP binding loops; other site
866768008668	ABC-ATPase subunit interface; other site
866768008669	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
866768008670	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866768008671	Walker A/P-loop; other site
866768008672	ATP binding site [chemical binding]; other site
866768008673	Q-loop/lid; other site
866768008674	ABC transporter signature motif; other site
866768008675	Walker B; other site
866768008676	D-loop; other site
866768008677	H-loop/switch region; other site
866768008678	TOBE domain; Region: TOBE_2; pfam08402
866768008679	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
866768008680	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
866768008681	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
866768008682	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
866768008683	RimK-like ATP-grasp domain; Region: RimK; pfam08443
866768008684	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
866768008685	dimer interface [polypeptide binding]; other site
866768008686	FMN binding site [chemical binding]; other site
866768008687	NADPH bind site [chemical binding]; other site
866768008688	Protein of unknown function (DUF1418); Region: DUF1418; pfam07214
866768008689	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
866768008690	GSH binding site [chemical binding]; other site
866768008691	catalytic residues [active]
866768008692	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
866768008693	putative transporter; Provisional; Region: PRK04972
866768008694	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
866768008695	TrkA-C domain; Region: TrkA_C; pfam02080
866768008696	TrkA-C domain; Region: TrkA_C; pfam02080
866768008697	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
866768008698	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
866768008699	Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606
866768008700	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
866768008701	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
866768008702	catalytic residues [active]
866768008703	catalytic nucleophile [active]
866768008704	Phage Tail Collar Domain; Region: Collar; pfam07484
866768008705	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
866768008706	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
866768008707	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
866768008708	Bacteriophage P2-related tail formation protein [General function prediction only]; Region: gpI; COG4385
866768008709	baseplate assembly protein; Provisional; Region: J; PHA02568
866768008710	baseplate wedge subunit; Provisional; Region: W; PHA02516
866768008711	phage baseplate assembly protein V; Region: phage_P2_V; TIGR01644
866768008712	Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540
866768008713	Phage virion morphogenesis family; Region: Phage_tail_S; pfam05069
866768008714	P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891
866768008715	phage lysis regulatory protein, LysB family; Region: phage_LysB; TIGR03495
866768008716	Phage capsid scaffolding protein (GPO) serine peptidase; Region: Phage_GPO; pfam05929
866768008717	terminase ATPase subunit; Provisional; Region: P; PHA02535
866768008718	Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056
866768008719	Mu-like prophage FluMu protein gp28 [General function prediction only]; Region: COG4373
866768008720	portal vertex protein; Provisional; Region: Q; PHA02536
866768008721	Phage portal protein; Region: Phage_portal; pfam04860
866768008722	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
866768008723	RT_Bac_retron_II: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_II; cd03487
866768008724	putative active site [active]
866768008725	putative NTP binding site [chemical binding]; other site
866768008726	putative nucleic acid binding site [nucleotide binding]; other site
866768008727	DinI-like family; Region: DinI; pfam06183
866768008728	Phage regulatory protein CII (CP76); Region: Phage_CP76; pfam06892
866768008729	Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; cl15276
866768008730	Predicted transcriptional regulator [Transcription]; Region: COG2932
866768008731	Bacteriophage CI repressor helix-turn-helix domain; Region: Phage_CI_repr; pfam07022
866768008732	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
866768008733	Catalytic site [active]
866768008734	hypothetical protein; Provisional; Region: PRK10040
866768008735	integrase; Provisional; Region: int; PHA02601
866768008736	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
866768008737	active site
866768008738	DNA binding site [nucleotide binding]
866768008739	Int/Topo IB signature motif; other site
866768008740	transcriptional repressor BetI; Region: betaine_BetI; TIGR03384
866768008741	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
866768008742	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
866768008743	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768008744	putative substrate translocation pore; other site
866768008745	Major Facilitator Superfamily; Region: MFS_1; pfam07690
866768008746	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
866768008747	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866768008748	active site
866768008749	motif I; other site
866768008750	motif II; other site
866768008751	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866768008752	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
866768008753	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
866768008754	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768008755	putative substrate translocation pore; other site
866768008756	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
866768008757	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
866768008758	active site
866768008759	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
866768008760	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
866768008761	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
866768008762	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
866768008763	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
866768008764	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
866768008765	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
866768008766	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
866768008767	putative C-terminal domain interface [polypeptide binding]; other site
866768008768	putative GSH binding site (G-site) [chemical binding]; other site
866768008769	putative dimer interface [polypeptide binding]; other site
866768008770	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
866768008771	N-terminal domain interface [polypeptide binding]; other site
866768008772	dimer interface [polypeptide binding]; other site
866768008773	substrate binding pocket (H-site) [chemical binding]; other site
866768008774	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
866768008775	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
866768008776	biofilm formation regulatory protein BssR; Reviewed; Region: bssR; PRK12302
866768008777	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
866768008778	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
866768008779	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866768008780	FeS/SAM binding site; other site
866768008781	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
866768008782	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
866768008783	metal binding site [ion binding]; metal-binding site
866768008784	active site
866768008785	I-site; other site
866768008786	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
866768008787	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
866768008788	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768008789	dimer interface [polypeptide binding]; other site
866768008790	conserved gate region; other site
866768008791	putative PBP binding loops; other site
866768008792	ABC-ATPase subunit interface; other site
866768008793	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
866768008794	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768008795	dimer interface [polypeptide binding]; other site
866768008796	conserved gate region; other site
866768008797	putative PBP binding loops; other site
866768008798	ABC-ATPase subunit interface; other site
866768008799	glutathione ABC transporter substrate-binding protein GsiB; Provisional; Region: PRK15413
866768008800	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
866768008801	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
866768008802	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
866768008803	Walker A/P-loop; other site
866768008804	ATP binding site [chemical binding]; other site
866768008805	Q-loop/lid; other site
866768008806	ABC transporter signature motif; other site
866768008807	Walker B; other site
866768008808	D-loop; other site
866768008809	H-loop/switch region; other site
866768008810	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
866768008811	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
866768008812	Walker A/P-loop; other site
866768008813	ATP binding site [chemical binding]; other site
866768008814	Q-loop/lid; other site
866768008815	ABC transporter signature motif; other site
866768008816	Walker B; other site
866768008817	D-loop; other site
866768008818	H-loop/switch region; other site
866768008819	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
866768008820	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
866768008821	catalytic nucleophile [active]
866768008822	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
866768008823	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
866768008824	dimer interface [polypeptide binding]; other site
866768008825	putative functional site; other site
866768008826	putative MPT binding site; other site
866768008827	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
866768008828	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
866768008829	ATP binding site [chemical binding]; other site
866768008830	substrate interface [chemical binding]; other site
866768008831	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
866768008832	active site
866768008833	intersubunit interactions; other site
866768008834	catalytic residue [active]
866768008835	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
866768008836	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
866768008837	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
866768008838	dimer interface [polypeptide binding]; other site
866768008839	active site
866768008840	glycine loop; other site
866768008841	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
866768008842	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866768008843	active site
866768008844	motif I; other site
866768008845	motif II; other site
866768008846	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866768008847	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
866768008848	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
866768008849	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866768008850	Walker A/P-loop; other site
866768008851	ATP binding site [chemical binding]; other site
866768008852	Q-loop/lid; other site
866768008853	ABC transporter signature motif; other site
866768008854	Walker B; other site
866768008855	D-loop; other site
866768008856	H-loop/switch region; other site
866768008857	ABC transporter; Region: ABC_tran_2; pfam12848
866768008858	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
866768008859	L,D-transpeptidase; Provisional; Region: PRK10260
866768008860	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
866768008861	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
866768008862	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
866768008863	transmembrane helices; other site
866768008864	manganese transport regulator MntR; Provisional; Region: PRK11050
866768008865	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
866768008866	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
866768008867	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
866768008868	Sulfatase; Region: Sulfatase; pfam00884
866768008869	outer membrane protein X; Provisional; Region: ompX; PRK09408
866768008870	threonine and homoserine efflux system; Provisional; Region: PRK10532
866768008871	EamA-like transporter family; Region: EamA; pfam00892
866768008872	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
866768008873	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
866768008874	dimerization interface [polypeptide binding]; other site
866768008875	DPS ferroxidase diiron center [ion binding]; other site
866768008876	ion pore; other site
866768008877	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
866768008878	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
866768008879	substrate binding pocket [chemical binding]; other site
866768008880	membrane-bound complex binding site; other site
866768008881	hinge residues; other site
866768008882	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
866768008883	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768008884	dimer interface [polypeptide binding]; other site
866768008885	conserved gate region; other site
866768008886	putative PBP binding loops; other site
866768008887	ABC-ATPase subunit interface; other site
866768008888	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
866768008889	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
866768008890	Walker A/P-loop; other site
866768008891	ATP binding site [chemical binding]; other site
866768008892	Q-loop/lid; other site
866768008893	ABC transporter signature motif; other site
866768008894	Walker B; other site
866768008895	D-loop; other site
866768008896	H-loop/switch region; other site
866768008897	putative mechanosensitive channel protein; Provisional; Region: PRK11465
866768008898	Mechanosensitive ion channel; Region: MS_channel; pfam00924
866768008899	23S rRNA mA1618 methyltransferase; Provisional; Region: PRK11727
866768008900	Protein of unknown function (DUF890); Region: Methyltransf_10; pfam05971
866768008901	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
866768008902	catecholate siderophore receptor Fiu; Provisional; Region: PRK09840
866768008903	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
866768008904	N-terminal plug; other site
866768008905	ligand-binding site [chemical binding]; other site
866768008906	Fe(II)-dependent oxygenase superfamily protein; Provisional; Region: PRK05467
866768008907	hypothetical protein; Provisional; Region: PRK11019
866768008908	hypothetical protein; Provisional; Region: PRK10259
866768008909	putative dehydrogenase; Provisional; Region: PRK10098
866768008910	glycosyl transferase family protein; Provisional; Region: PRK08136
866768008911	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
866768008912	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
866768008913	DEAD_2; Region: DEAD_2; pfam06733
866768008914	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
866768008915	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3236
866768008916	helicase 45; Provisional; Region: PTZ00424
866768008917	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
866768008918	ATP binding site [chemical binding]; other site
866768008919	Mg++ binding site [ion binding]; other site
866768008920	motif III; other site
866768008921	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
866768008922	nucleotide binding region [chemical binding]; other site
866768008923	ATP-binding site [chemical binding]; other site
866768008924	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
866768008925	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
866768008926	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
866768008927	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
866768008928	HlyD family secretion protein; Region: HlyD_3; pfam13437
866768008929	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
866768008930	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
866768008931	Walker A/P-loop; other site
866768008932	ATP binding site [chemical binding]; other site
866768008933	Q-loop/lid; other site
866768008934	ABC transporter signature motif; other site
866768008935	Walker B; other site
866768008936	D-loop; other site
866768008937	H-loop/switch region; other site
866768008938	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
866768008939	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
866768008940	Walker A/P-loop; other site
866768008941	ATP binding site [chemical binding]; other site
866768008942	Q-loop/lid; other site
866768008943	ABC transporter signature motif; other site
866768008944	Walker B; other site
866768008945	D-loop; other site
866768008946	H-loop/switch region; other site
866768008947	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
866768008948	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
866768008949	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
866768008950	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
866768008951	Putative inner membrane protein YbhQ; Region: YbhQ; pfam11076
866768008952	Metal-dependent hydrolase [General function prediction only]; Region: ElsH; COG3568
866768008953	putative catalytic site [active]
866768008954	putative metal binding site [ion binding]; other site
866768008955	putative phosphate binding site [ion binding]; other site
866768008956	cardiolipin synthase 2; Provisional; Region: PRK11263
866768008957	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
866768008958	putative active site [active]
866768008959	catalytic site [active]
866768008960	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
866768008961	putative active site [active]
866768008962	catalytic site [active]
866768008963	Predicted integral membrane protein [Function unknown]; Region: COG0392
866768008964	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
866768008965	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
866768008966	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
866768008967	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
866768008968	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
866768008969	MoaE homodimer interface [polypeptide binding]; other site
866768008970	MoaD interaction [polypeptide binding]; other site
866768008971	active site residues [active]
866768008972	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
866768008973	MoaE interaction surface [polypeptide binding]; other site
866768008974	MoeB interaction surface [polypeptide binding]; other site
866768008975	thiocarboxylated glycine; other site
866768008976	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
866768008977	trimer interface [polypeptide binding]; other site
866768008978	dimer interface [polypeptide binding]; other site
866768008979	putative active site [active]
866768008980	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
866768008981	MPT binding site; other site
866768008982	trimer interface [polypeptide binding]; other site
866768008983	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
866768008984	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866768008985	FeS/SAM binding site; other site
866768008986	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
866768008987	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
866768008988	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
866768008989	putative substrate binding pocket [chemical binding]; other site
866768008990	dimer interface [polypeptide binding]; other site
866768008991	phosphate binding site [ion binding]; other site
866768008992	excinuclease ABC subunit B; Provisional; Region: PRK05298
866768008993	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
866768008994	ATP binding site [chemical binding]; other site
866768008995	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
866768008996	nucleotide binding region [chemical binding]; other site
866768008997	ATP-binding site [chemical binding]; other site
866768008998	Ultra-violet resistance protein B; Region: UvrB; pfam12344
866768008999	UvrB/uvrC motif; Region: UVR; pfam02151
866768009000	AAA domain; Region: AAA_26; pfam13500
866768009001	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
866768009002	Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the biotin biosynthesis pathway in Escherichia coli and other microorganisms. The enzyme catalyzes formation of the ureido ring of dethiobiotin from (7R,8S)-7,8-diaminononanoic acid (DAPA) and...; Region: DTBS; cd03109
866768009003	ADP binding site [chemical binding]; other site
866768009004	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
866768009005	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768009006	S-adenosylmethionine binding site [chemical binding]; other site
866768009007	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
866768009008	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
866768009009	substrate-cofactor binding pocket; other site
866768009010	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768009011	catalytic residue [active]
866768009012	biotin synthase; Provisional; Region: PRK15108
866768009013	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866768009014	FeS/SAM binding site; other site
866768009015	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
866768009016	adenosylmethionine--8-amino-7-oxononanoate transaminase; Validated; Region: PRK07986
866768009017	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
866768009018	inhibitor-cofactor binding pocket; inhibition site
866768009019	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768009020	catalytic residue [active]
866768009021	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
866768009022	substrate binding site [chemical binding]; other site
866768009023	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; cl17254
866768009024	Phage-related protein, tail component [Function unknown]; Region: COG4733
866768009025	Putative phage tail protein; Region: Phage-tail_3; pfam13550
866768009026	Domain of unknown function (DUF1983); Region: DUF1983; pfam09327
866768009027	Fibronectin type III protein; Region: DUF3672; pfam12421
866768009028	Phage-related protein, tail component [Function unknown]; Region: COG4723
866768009029	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding) found in proteins also containing NlpC/P60 domains; Region: MPN_NLPC_P60; cd08073
866768009030	MPN+ (JAMM) motif; other site
866768009031	Zinc-binding site [ion binding]; other site
866768009032	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
866768009033	NlpC/P60 family; Region: NLPC_P60; cl17555
866768009034	Phage-related protein [Function unknown]; Region: gp18; COG4672
866768009035	Phage-related protein [Function unknown]; Region: COG4718
866768009036	Phage-related minor tail protein [Function unknown]; Region: COG5281
866768009037	Prophage tail length tape measure protein; Region: TMP_2; pfam06791
866768009038	Lambda phage tail tape-measure protein (Tape_meas_lam_C); Region: Tape_meas_lam_C; pfam09718
866768009039	Minor tail protein T; Region: Phage_tail_T; pfam06223
866768009040	phage minor tail protein G; Region: phage_lambda_G; TIGR01674
866768009041	Bacterial surface proteins containing Ig-like domains [Cell motility and secretion]; Region: COG5492
866768009042	Bacterial Ig-like domain (group 2); Region: Big_2; pfam02368
866768009043	Phage minor tail protein U; Region: Phage_tail_U; pfam06141
866768009044	Prophage minor tail protein Z (GPZ); Region: Minor_tail_Z; pfam06763
866768009045	Phage Head-Tail Attachment; Region: Phage_attach; pfam05354
866768009046	DNA packaging protein FI; Region: Packaging_FI; pfam14000
866768009047	Phage major capsid protein E; Region: Phage_cap_E; pfam03864
866768009048	Bacteriophage lambda head decoration protein D; Region: HDPD; pfam02924
866768009049	Signal peptide peptidase A (SppA) 36K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_36K_type; cd07022
866768009050	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
866768009051	tandem repeat interface [polypeptide binding]; other site
866768009052	oligomer interface [polypeptide binding]; other site
866768009053	active site residues [active]
866768009054	Bacteriophage capsid protein [General function prediction only]; Region: COG5511
866768009055	phage portal protein, lambda family; Region: portal_lambda; TIGR01539
866768009056	gpW; Region: gpW; pfam02831
866768009057	Phage terminase, large subunit GpA [Replication, recombination and repair]; Region: COG5525
866768009058	Phage DNA packaging protein Nu1; Region: Phage_Nu1; pfam07471
866768009059	Domain of unknown function (DUF3950); Region: DUF3950; pfam13132
866768009060	Protein of unknown function (DUF1398); Region: DUF1398; pfam07166
866768009061	Bor protein; Region: Lambda_Bor; pfam06291
866768009062	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
866768009063	The lysozyme from bacteriophage lambda hydrolyses the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc), as do other lysozymes.  But unlike other lysozymes, bacteriophage lambda does not produce a reducing...; Region: bacteriophage_lambda_lysozyme; cd00736
866768009064	N-acetyl-D-glucosamine binding site [chemical binding]; other site
866768009065	catalytic residue [active]
866768009066	phage holin, lambda family; Region: holin_lambda; TIGR01594
866768009067	Antitermination protein; Region: Antiterm; pfam03589
866768009068	Antitermination protein; Region: Antiterm; pfam03589
866768009069	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
866768009070	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
866768009071	active site
866768009072	metal binding site [ion binding]; metal-binding site
866768009073	Replication protein P; Region: Phage_lambda_P; pfam06992
866768009074	Bacteriophage replication protein O; Region: Phage_rep_O; pfam04492
866768009075	Bacteriophage CII protein; Region: Phage_CII; pfam05269
866768009076	DNA-binding transcriptional regulator DicC; Provisional; Region: PRK09744
866768009077	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
866768009078	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
866768009079	non-specific DNA binding site [nucleotide binding]; other site
866768009080	salt bridge; other site
866768009081	sequence-specific DNA binding site [nucleotide binding]; other site
866768009082	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
866768009083	Catalytic site [active]
866768009084	Antirestriction protein Ral; Region: Ral; pfam11058
866768009085	Protein of unknown function (DUF2528); Region: DUF2528; pfam10800
866768009086	Lambda Phage CIII; Region: Lambda_CIII; pfam02061
866768009087	Bacteriophage lambda Kil protein; Region: Lambda_Kil; pfam06301
866768009088	Host-nuclease inhibitor protein Gam; Region: Gam; pfam06064
866768009089	phage recombination protein Bet; Region: bet_lambda; TIGR01913
866768009090	YqaJ-like viral recombinase domain; Region: YqaJ; pfam09588
866768009091	Protein of unknown function (DUF1317); Region: DUF1317; pfam07026
866768009092	Protein of unknown function (DUF1382); Region: DUF1382; pfam07131
866768009093	Ead/Ea22-like protein; Region: Ead_Ea22; pfam13935
866768009094	Excisionase-like protein; Region: Exc; pfam07825
866768009095	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
866768009096	Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N; cl12235
866768009097	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
866768009098	T3/T7-like RNA polymerase; Region: PHA00452
866768009099	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
866768009100	lac repressor; Reviewed; Region: lacI; PRK09526
866768009101	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
866768009102	DNA binding site [nucleotide binding]
866768009103	domain linker motif; other site
866768009104	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
866768009105	ligand binding site [chemical binding]; other site
866768009106	dimerization interface (open form) [polypeptide binding]; other site
866768009107	dimerization interface (closed form) [polypeptide binding]; other site
866768009108	acyl-CoA thioesterase; Provisional; Region: PRK10531
866768009109	putative pectinesterase; Region: PLN02432; cl01911
866768009110	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
866768009111	catalytic core [active]
866768009112	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
866768009113	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
866768009114	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
866768009115	YbgS-like protein; Region: YbgS; pfam13985
866768009116	zinc transporter ZitB; Provisional; Region: PRK03557
866768009117	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
866768009118	quinolinate synthetase; Provisional; Region: PRK09375
866768009119	tol-pal system protein YbgF; Provisional; Region: PRK10803
866768009120	Tetratricopeptide repeat; Region: TPR_6; pfam13174
866768009121	Tetratricopeptide repeat; Region: TPR_6; pfam13174
866768009122	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
866768009123	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
866768009124	ligand binding site [chemical binding]; other site
866768009125	translocation protein TolB; Provisional; Region: tolB; PRK03629
866768009126	TolB amino-terminal domain; Region: TolB_N; pfam04052
866768009127	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
866768009128	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
866768009129	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
866768009130	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
866768009131	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
866768009132	TolA C-terminal; Region: TolA; pfam06519
866768009133	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
866768009134	colicin uptake protein TolR; Provisional; Region: PRK11024
866768009135	colicin uptake protein TolQ; Provisional; Region: PRK10801
866768009136	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
866768009137	active site
866768009138	hypothetical protein; Provisional; Region: PRK10588
866768009139	Membrane bound YbgT-like protein; Region: YbgT_YccB; cl02039
866768009140	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003
866768009141	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
866768009142	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
866768009143	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562
866768009144	alpha-mannosidase; Provisional; Region: PRK09819
866768009145	N-terminal catalytic domain of Escherichia coli alpha-mannosidase MngB and its bacterial homologs; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_EcMngB_like; cd10815
866768009146	active site
866768009147	metal binding site [ion binding]; metal-binding site
866768009148	catalytic site [active]
866768009149	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; smart00872
866768009150	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
866768009151	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
866768009152	active site
866768009153	phosphorylation site [posttranslational modification]
866768009154	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
866768009155	active site
866768009156	P-loop; other site
866768009157	phosphorylation site [posttranslational modification]
866768009158	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
866768009159	DNA-binding transcriptional repressor MngR; Provisional; Region: PRK09764
866768009160	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
866768009161	DNA-binding site [nucleotide binding]; DNA binding site
866768009162	UTRA domain; Region: UTRA; pfam07702
866768009163	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
866768009164	CoA binding domain; Region: CoA_binding; smart00881
866768009165	CoA-ligase; Region: Ligase_CoA; pfam00549
866768009166	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
866768009167	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
866768009168	CoA-ligase; Region: Ligase_CoA; pfam00549
866768009169	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
866768009170	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
866768009171	E3 interaction surface; other site
866768009172	lipoyl attachment site [posttranslational modification]; other site
866768009173	e3 binding domain; Region: E3_binding; pfam02817
866768009174	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
866768009175	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
866768009176	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
866768009177	TPP-binding site [chemical binding]; other site
866768009178	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
866768009179	dimer interface [polypeptide binding]; other site
866768009180	PYR/PP interface [polypeptide binding]; other site
866768009181	TPP binding site [chemical binding]; other site
866768009182	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
866768009183	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
866768009184	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
866768009185	L-aspartate oxidase; Provisional; Region: PRK06175
866768009186	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
866768009187	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
866768009188	SdhC subunit interface [polypeptide binding]; other site
866768009189	proximal heme binding site [chemical binding]; other site
866768009190	cardiolipin binding site; other site
866768009191	Iron-sulfur protein interface; other site
866768009192	proximal quinone binding site [chemical binding]; other site
866768009193	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
866768009194	Iron-sulfur protein interface; other site
866768009195	proximal quinone binding site [chemical binding]; other site
866768009196	SdhD (CybS) interface [polypeptide binding]; other site
866768009197	proximal heme binding site [chemical binding]; other site
866768009198	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
866768009199	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
866768009200	dimer interface [polypeptide binding]; other site
866768009201	active site
866768009202	citrylCoA binding site [chemical binding]; other site
866768009203	NADH binding [chemical binding]; other site
866768009204	cationic pore residues; other site
866768009205	oxalacetate/citrate binding site [chemical binding]; other site
866768009206	coenzyme A binding site [chemical binding]; other site
866768009207	catalytic triad [active]
866768009208	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
866768009209	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
866768009210	PapC N-terminal domain; Region: PapC_N; pfam13954
866768009211	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
866768009212	PapC C-terminal domain; Region: PapC_C; pfam13953
866768009213	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
866768009214	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
866768009215	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
866768009216	Fimbrial protein; Region: Fimbrial; pfam00419
866768009217	Putative ammonia monooxygenase [General function prediction only]; Region: AbrB; COG3180
866768009218	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
866768009219	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
866768009220	endonuclease VIII; Provisional; Region: PRK10445
866768009221	N-terminal domain of Escherichia coli Nei/endonuclease VIII and related DNA glycosylases; Region: EcNei-like_N; cd08965
866768009222	DNA binding site [nucleotide binding]
866768009223	catalytic residue [active]
866768009224	putative catalytic residues [active]
866768009225	H2TH interface [polypeptide binding]; other site
866768009226	intercalation triad [nucleotide binding]; other site
866768009227	substrate specificity determining residue; other site
866768009228	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
866768009229	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
866768009230	Escherichia coli putative lactam utilization protein YbgL and similar proteins; Region: LamB_YcsF_YbgL_like; cd10800
866768009231	putative active site [active]
866768009232	biotin-dependent carboxylase uncharacterized domain; Region: urea_amlyse_rel; TIGR00724
866768009233	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
866768009234	sensor histidine kinase inhibitor, KipI family; Region: TIGR00370
866768009235	Uncharacterized conserved protein [Function unknown]; Region: COG0327
866768009236	metal-binding protein; Provisional; Region: PRK10799
866768009237	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
866768009238	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768009239	putative substrate translocation pore; other site
866768009240	POT family; Region: PTR2; pfam00854
866768009241	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
866768009242	DNA photolyase; Region: DNA_photolyase; pfam00875
866768009243	hypothetical protein; Provisional; Region: PRK10167
866768009244	Uncharacterized conserved protein [Function unknown]; Region: COG3272
866768009245	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
866768009246	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
866768009247	Transposase [DNA replication, recombination, and repair]; Region: COG5433
866768009248	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
866768009249	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
866768009250	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
866768009251	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
866768009252	potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315
866768009253	sensor protein KdpD; Provisional; Region: PRK10490
866768009254	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
866768009255	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
866768009256	Ligand Binding Site [chemical binding]; other site
866768009257	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
866768009258	GAF domain; Region: GAF_3; pfam13492
866768009259	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
866768009260	dimer interface [polypeptide binding]; other site
866768009261	phosphorylation site [posttranslational modification]
866768009262	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866768009263	ATP binding site [chemical binding]; other site
866768009264	Mg2+ binding site [ion binding]; other site
866768009265	G-X-G motif; other site
866768009266	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
866768009267	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768009268	active site
866768009269	phosphorylation site [posttranslational modification]
866768009270	intermolecular recognition site; other site
866768009271	dimerization interface [polypeptide binding]; other site
866768009272	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
866768009273	DNA binding site [nucleotide binding]
866768009274	ornithine decarboxylase; Provisional; Region: PRK13578
866768009275	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
866768009276	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
866768009277	homodimer interface [polypeptide binding]; other site
866768009278	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768009279	catalytic residue [active]
866768009280	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
866768009281	putrescine transporter; Provisional; Region: potE; PRK10655
866768009282	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
866768009283	Protein of unknown function DUF2625; Region: DUF2625; pfam10946
866768009284	phosphoglucomutase, alpha-D-glucose phosphate-specific; Region: pgm; TIGR01132
866768009285	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
866768009286	active site
866768009287	substrate binding site [chemical binding]; other site
866768009288	metal binding site [ion binding]; metal-binding site
866768009289	replication initiation regulator SeqA; Provisional; Region: PRK11187
866768009290	acyl-CoA esterase; Provisional; Region: PRK10673
866768009291	PGAP1-like protein; Region: PGAP1; pfam07819
866768009292	LexA regulated protein; Provisional; Region: PRK11675
866768009293	flavodoxin FldA; Validated; Region: PRK09267
866768009294	ferric uptake regulator; Provisional; Region: fur; PRK09462
866768009295	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
866768009296	metal binding site 2 [ion binding]; metal-binding site
866768009297	putative DNA binding helix; other site
866768009298	metal binding site 1 [ion binding]; metal-binding site
866768009299	dimer interface [polypeptide binding]; other site
866768009300	structural Zn2+ binding site [ion binding]; other site
866768009301	YbfN-like lipoprotein; Region: YbfN; pfam13982
866768009302	outer membrane porin, OprD family; Region: OprD; pfam03573
866768009303	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
866768009304	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
866768009305	active site
866768009306	HIGH motif; other site
866768009307	nucleotide binding site [chemical binding]; other site
866768009308	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
866768009309	KMSKS motif; other site
866768009310	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
866768009311	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
866768009312	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
866768009313	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
866768009314	active site turn [active]
866768009315	phosphorylation site [posttranslational modification]
866768009316	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
866768009317	HPr interaction site; other site
866768009318	glycerol kinase (GK) interaction site [polypeptide binding]; other site
866768009319	active site
866768009320	phosphorylation site [posttranslational modification]
866768009321	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
866768009322	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
866768009323	active site
866768009324	trimer interface [polypeptide binding]; other site
866768009325	allosteric site; other site
866768009326	active site lid [active]
866768009327	hexamer (dimer of trimers) interface [polypeptide binding]; other site
866768009328	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
866768009329	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
866768009330	active site
866768009331	dimer interface [polypeptide binding]; other site
866768009332	MarR family; Region: MarR; pfam01047
866768009333	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
866768009334	ROK family; Region: ROK; pfam00480
866768009335	UMP phosphatase; Provisional; Region: PRK10444
866768009336	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866768009337	active site
866768009338	motif I; other site
866768009339	motif II; other site
866768009340	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866768009341	asparagine synthetase B; Provisional; Region: asnB; PRK09431
866768009342	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
866768009343	active site
866768009344	dimer interface [polypeptide binding]; other site
866768009345	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
866768009346	Ligand Binding Site [chemical binding]; other site
866768009347	Molecular Tunnel; other site
866768009348	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
866768009349	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
866768009350	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
866768009351	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
866768009352	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866768009353	FeS/SAM binding site; other site
866768009354	TRAM domain; Region: TRAM; pfam01938
866768009355	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
866768009356	PhoH-like protein; Region: PhoH; pfam02562
866768009357	metal-binding heat shock protein; Provisional; Region: PRK00016
866768009358	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
866768009359	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
866768009360	Transporter associated domain; Region: CorC_HlyC; smart01091
866768009361	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
866768009362	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
866768009363	putative active site [active]
866768009364	catalytic triad [active]
866768009365	putative dimer interface [polypeptide binding]; other site
866768009366	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
866768009367	PQQ-dependent catabolism-associated beta-propeller protein; Region: PQQ_ABC_repeats; TIGR03866
866768009368	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
866768009369	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
866768009370	glutamate and aspartate transporter subunit; Provisional; Region: PRK10797
866768009371	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
866768009372	substrate binding pocket [chemical binding]; other site
866768009373	membrane-bound complex binding site; other site
866768009374	hinge residues; other site
866768009375	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
866768009376	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768009377	dimer interface [polypeptide binding]; other site
866768009378	conserved gate region; other site
866768009379	putative PBP binding loops; other site
866768009380	ABC-ATPase subunit interface; other site
866768009381	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
866768009382	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768009383	dimer interface [polypeptide binding]; other site
866768009384	conserved gate region; other site
866768009385	putative PBP binding loops; other site
866768009386	ABC-ATPase subunit interface; other site
866768009387	putative transposase OrfB; Reviewed; Region: PHA02517
866768009388	HTH-like domain; Region: HTH_21; pfam13276
866768009389	Integrase core domain; Region: rve; pfam00665
866768009390	Integrase core domain; Region: rve_2; pfam13333
866768009391	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
866768009392	Helix-turn-helix domain; Region: HTH_28; pfam13518
866768009393	Helix-turn-helix domain; Region: HTH_28; pfam13518
866768009394	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
866768009395	active site
866768009396	tetramer interface [polypeptide binding]; other site
866768009397	Molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: DnaK; COG0443
866768009398	Nucleotide-binding domain of Escherichia coli HscC and similar proteins; Region: HscC_like_NBD; cd10235
866768009399	nucleotide binding site [chemical binding]; other site
866768009400	putative NEF/HSP70 interaction site [polypeptide binding]; other site
866768009401	SBD interface [polypeptide binding]; other site
866768009402	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
866768009403	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
866768009404	Sel1-like repeats; Region: SEL1; smart00671
866768009405	Sel1-like repeats; Region: SEL1; smart00671
866768009406	Sel1-like repeats; Region: SEL1; smart00671
866768009407	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
866768009408	Sel1-like repeats; Region: SEL1; smart00671
866768009409	Sel1-like repeats; Region: SEL1; smart00671
866768009410	hypothetical protein; Provisional; Region: PRK11032
866768009411	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
866768009412	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
866768009413	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
866768009414	HIGH motif; other site
866768009415	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
866768009416	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
866768009417	active site
866768009418	KMSKS motif; other site
866768009419	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
866768009420	tRNA binding surface [nucleotide binding]; other site
866768009421	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
866768009422	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
866768009423	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
866768009424	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
866768009425	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
866768009426	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
866768009427	active site
866768009428	(T/H)XGH motif; other site
866768009429	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
866768009430	catalytic core [active]
866768009431	ribosome-associated protein; Provisional; Region: PRK11538
866768009432	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
866768009433	penicillin-binding protein 2; Provisional; Region: PRK10795
866768009434	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
866768009435	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
866768009436	cell wall shape-determining protein; Provisional; Region: PRK10794
866768009437	rare lipoprotein A; Provisional; Region: PRK10672
866768009438	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
866768009439	Sporulation related domain; Region: SPOR; pfam05036
866768009440	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
866768009441	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
866768009442	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
866768009443	hypothetical protein; Provisional; Region: PRK04998
866768009444	lipoate-protein ligase B; Provisional; Region: PRK14342
866768009445	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
866768009446	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768009447	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
866768009448	substrate binding pocket [chemical binding]; other site
866768009449	dimerization interface [polypeptide binding]; other site
866768009450	lipoyl synthase; Provisional; Region: PRK05481
866768009451	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866768009452	FeS/SAM binding site; other site
866768009453	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
866768009454	Predicted amidohydrolase [General function prediction only]; Region: COG0388
866768009455	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_3; cd07581
866768009456	putative active site [active]
866768009457	catalytic triad [active]
866768009458	putative dimer interface [polypeptide binding]; other site
866768009459	chromosome condensation membrane protein; Provisional; Region: PRK14196
866768009460	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
866768009461	DNA-binding site [nucleotide binding]; DNA binding site
866768009462	RNA-binding motif; other site
866768009463	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
866768009464	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
866768009465	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
866768009466	two-component response regulator DpiA; Provisional; Region: dpiA; PRK10046
866768009467	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768009468	active site
866768009469	phosphorylation site [posttranslational modification]
866768009470	intermolecular recognition site; other site
866768009471	dimerization interface [polypeptide binding]; other site
866768009472	Transcriptional regulator; Region: CitT; pfam12431
866768009473	sensor histidine kinase DpiB; Provisional; Region: dpiB; PRK15053
866768009474	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
866768009475	putative active site [active]
866768009476	heme pocket [chemical binding]; other site
866768009477	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866768009478	ATP binding site [chemical binding]; other site
866768009479	Mg2+ binding site [ion binding]; other site
866768009480	G-X-G motif; other site
866768009481	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
866768009482	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
866768009483	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
866768009484	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
866768009485	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
866768009486	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
866768009487	putative active site [active]
866768009488	(T/H)XGH motif; other site
866768009489	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
866768009490	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
866768009491	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
866768009492	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
866768009493	triphosphoribosyl-dephospho-CoA synthase; Provisional; Region: citG; PRK10096
866768009494	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
866768009495	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
866768009496	transmembrane helices; other site
866768009497	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062
866768009498	B1 nucleotide binding pocket [chemical binding]; other site
866768009499	B2 nucleotide binding pocket [chemical binding]; other site
866768009500	CAS motifs; other site
866768009501	active site
866768009502	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
866768009503	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
866768009504	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
866768009505	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
866768009506	NAD binding site [chemical binding]; other site
866768009507	catalytic Zn binding site [ion binding]; other site
866768009508	structural Zn binding site [ion binding]; other site
866768009509	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
866768009510	Ligand Binding Site [chemical binding]; other site
866768009511	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
866768009512	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
866768009513	catalytic residue [active]
866768009514	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
866768009515	catalytic residues [active]
866768009516	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
866768009517	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
866768009518	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
866768009519	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
866768009520	dimer interface [polypeptide binding]; other site
866768009521	decamer (pentamer of dimers) interface [polypeptide binding]; other site
866768009522	catalytic triad [active]
866768009523	peroxidatic and resolving cysteines [active]
866768009524	disulfide isomerase/thiol-disulfide oxidase; Provisional; Region: dsbG; PRK11657
866768009525	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
866768009526	dimerization domain [polypeptide binding]; other site
866768009527	dimer interface [polypeptide binding]; other site
866768009528	catalytic residues [active]
866768009529	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
866768009530	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
866768009531	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
866768009532	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
866768009533	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
866768009534	ParB-like nuclease domain; Region: ParBc; pfam02195
866768009535	methionine aminotransferase; Validated; Region: PRK09082
866768009536	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
866768009537	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768009538	homodimer interface [polypeptide binding]; other site
866768009539	catalytic residue [active]
866768009540	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
866768009541	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
866768009542	putative active site [active]
866768009543	metal binding site [ion binding]; metal-binding site
866768009544	Uncharacterized small protein [Function unknown]; Region: COG2879
866768009545	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
866768009546	CoenzymeA binding site [chemical binding]; other site
866768009547	subunit interaction site [polypeptide binding]; other site
866768009548	PHB binding site; other site
866768009549	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
866768009550	2,3 dihydro-2,3 dihydrozybenzoate dehydrogenases, classical (c) SDRs; Region: DH-DHB-DH_SDR_c; cd05331
866768009551	putative NAD(P) binding site [chemical binding]; other site
866768009552	active site
866768009553	Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013
866768009554	hydrophobic substrate binding pocket; other site
866768009555	Isochorismatase family; Region: Isochorismatase; pfam00857
866768009556	active site
866768009557	conserved cis-peptide bond; other site
866768009558	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
866768009559	enterobactin synthase subunit E; Provisional; Region: entE; PRK10946
866768009560	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
866768009561	acyl-activating enzyme (AAE) consensus motif; other site
866768009562	active site
866768009563	AMP binding site [chemical binding]; other site
866768009564	substrate binding site [chemical binding]; other site
866768009565	isochorismate synthase EntC; Provisional; Region: PRK15016
866768009566	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
866768009567	iron-enterobactin transporter periplasmic binding protein; Provisional; Region: PRK10957
866768009568	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
866768009569	siderophore binding site; other site
866768009570	enterobactin exporter EntS; Provisional; Region: PRK10489
866768009571	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768009572	putative substrate translocation pore; other site
866768009573	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
866768009574	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
866768009575	ABC-ATPase subunit  interface; other site
866768009576	dimer interface [polypeptide binding]; other site
866768009577	putative PBP binding regions; other site
866768009578	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
866768009579	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
866768009580	ABC-ATPase subunit  interface; other site
866768009581	dimer interface [polypeptide binding]; other site
866768009582	putative PBP binding regions; other site
866768009583	iron-enterobactin transporter ATP-binding protein; Provisional; Region: PRK10253
866768009584	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
866768009585	Walker A/P-loop; other site
866768009586	ATP binding site [chemical binding]; other site
866768009587	Q-loop/lid; other site
866768009588	ABC transporter signature motif; other site
866768009589	Walker B; other site
866768009590	D-loop; other site
866768009591	H-loop/switch region; other site
866768009592	LPS O-antigen length regulator; Provisional; Region: PRK10381
866768009593	Chain length determinant protein; Region: Wzz; pfam02706
866768009594	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
866768009595	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
866768009596	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
866768009597	acyl-activating enzyme (AAE) consensus motif; other site
866768009598	AMP binding site [chemical binding]; other site
866768009599	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
866768009600	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3251
866768009601	enterobactin/ferric enterobactin esterase; Provisional; Region: PRK10439
866768009602	Domain of unknown function (DUF3327); Region: DUF3327; pfam11806
866768009603	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
866768009604	outer membrane receptor FepA; Provisional; Region: PRK13524
866768009605	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
866768009606	N-terminal plug; other site
866768009607	ligand-binding site [chemical binding]; other site
866768009608	phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex; Provisional; Region: PRK10251
866768009609	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
866768009610	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
866768009611	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
866768009612	Hok/gef family; Region: HOK_GEF; pfam01848
866768009613	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
866768009614	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
866768009615	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
866768009616	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
866768009617	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
866768009618	Helix-turn-helix domain; Region: HTH_28; pfam13518
866768009619	Helix-turn-helix domain; Region: HTH_28; pfam13518
866768009620	gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516
866768009621	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
866768009622	Protein of unknown function (DUF1158); Region: DUF1158; pfam06643
866768009623	hypothetical protein; Provisional; Region: PRK10250
866768009624	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
866768009625	dimer interface [polypeptide binding]; other site
866768009626	FMN binding site [chemical binding]; other site
866768009627	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
866768009628	Mechanosensitive ion channel; Region: MS_channel; pfam00924
866768009629	phenylalanine transporter; Provisional; Region: PRK10249
866768009630	heavy metal efflux pump, CzcA family; Region: 2A0601; TIGR00914
866768009631	copper/silver efflux system membrane fusion protein CusB; Provisional; Region: PRK09783
866768009632	HlyD family secretion protein; Region: HlyD_3; pfam13437
866768009633	periplasmic copper-binding protein; Provisional; Region: PRK09838
866768009634	copper/silver efflux system outer membrane protein CusC; Provisional; Region: PRK09837
866768009635	DNA-binding transcriptional activator CusR; Provisional; Region: PRK09836
866768009636	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768009637	active site
866768009638	phosphorylation site [posttranslational modification]
866768009639	intermolecular recognition site; other site
866768009640	dimerization interface [polypeptide binding]; other site
866768009641	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
866768009642	DNA binding site [nucleotide binding]
866768009643	sensor kinase CusS; Provisional; Region: PRK09835
866768009644	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
866768009645	dimerization interface [polypeptide binding]; other site
866768009646	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
866768009647	dimer interface [polypeptide binding]; other site
866768009648	phosphorylation site [posttranslational modification]
866768009649	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866768009650	ATP binding site [chemical binding]; other site
866768009651	Mg2+ binding site [ion binding]; other site
866768009652	G-X-G motif; other site
866768009653	Phage DNA packaging protein Nu1; Region: Phage_Nu1; pfam07471
866768009654	Domain of unknown function (DUF3950); Region: DUF3950; pfam13132
866768009655	Bor protein; Region: Lambda_Bor; pfam06291
866768009656	Bacteriophage lysis protein; Region: Phage_lysis; pfam03245
866768009657	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
866768009658	catalytic residues [active]
866768009659	Lysis protein S; Region: Lysis_S; pfam04971
866768009660	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
866768009661	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
866768009662	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
866768009663	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
866768009664	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
866768009665	endodeoxyribonuclease RUS; Reviewed; Region: PRK09786
866768009666	Protein of unknown function (DUF1364); Region: DUF1364; pfam07102
866768009667	prophage protein NinE; Provisional; Region: PRK09689
866768009668	hypothetical protein; Provisional; Region: PRK09741
866768009669	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
866768009670	Defensin propeptide; Region: Defensin_propep; pfam00879
866768009671	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
866768009672	substrate binding site [chemical binding]; other site
866768009673	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
866768009674	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
866768009675	catalytic residues [active]
866768009676	catalytic nucleophile [active]
866768009677	Recombinase; Region: Recombinase; pfam07508
866768009678	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
866768009679	multidrug efflux protein; Reviewed; Region: emrE; PRK09541
866768009680	DksA-like zinc finger domain containing protein; Region: PHA00080
866768009681	Domain of unknown function (DUF4222); Region: DUF4222; pfam13973
866768009682	Helix-turn-helix domain; Region: HTH_17; pfam12728
866768009683	P22-like integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial and phage integrases, including those similar to phage P22-like integrases, DLP12 and APSE-1; Region: INT_P22_C; cd01192
866768009684	Int/Topo IB signature motif; other site
866768009685	transcriptional regulator FimZ; Provisional; Region: PRK09935
866768009686	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768009687	active site
866768009688	phosphorylation site [posttranslational modification]
866768009689	intermolecular recognition site; other site
866768009690	dimerization interface [polypeptide binding]; other site
866768009691	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
866768009692	DNA binding residues [nucleotide binding]
866768009693	dimerization interface [polypeptide binding]; other site
866768009694	fimbrial-like adhesin protein SfmF; Provisional; Region: PRK09934
866768009695	fimbrial-like adhesin; Provisional; Region: fimH; PRK15199
866768009696	outer membrane usher protein FimD; Provisional; Region: PRK15198
866768009697	PapC N-terminal domain; Region: PapC_N; pfam13954
866768009698	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
866768009699	PapC C-terminal domain; Region: PapC_C; pfam13953
866768009700	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
866768009701	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
866768009702	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
866768009703	type-1 fimbrial protein subunit A; Provisional; Region: PRK15194
866768009704	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
866768009705	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
866768009706	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
866768009707	homodimer interface [polypeptide binding]; other site
866768009708	NADP binding site [chemical binding]; other site
866768009709	substrate binding site [chemical binding]; other site
866768009710	ribosome-associated protein; Provisional; Region: PRK11507
866768009711	Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988
866768009712	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
866768009713	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
866768009714	active site
866768009715	HIGH motif; other site
866768009716	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
866768009717	KMSKS motif; other site
866768009718	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
866768009719	tRNA binding surface [nucleotide binding]; other site
866768009720	anticodon binding site; other site
866768009721	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
866768009722	substrate binding site [chemical binding]; other site
866768009723	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
866768009724	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
866768009725	putative active site [active]
866768009726	putative metal binding site [ion binding]; other site
866768009727	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
866768009728	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
866768009729	ATP-grasp domain; Region: ATP-grasp; pfam02222
866768009730	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
866768009731	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
866768009732	putative substrate binding site [chemical binding]; other site
866768009733	nucleotide binding site [chemical binding]; other site
866768009734	nucleotide binding site [chemical binding]; other site
866768009735	homodimer interface [polypeptide binding]; other site
866768009736	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
866768009737	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
866768009738	membrane protein FdrA; Validated; Region: PRK06091
866768009739	CoA binding domain; Region: CoA_binding; pfam02629
866768009740	CoA-ligase; Region: Ligase_CoA; pfam00549
866768009741	ureidoglycolate dehydrogenase; Provisional; Region: PRK15025
866768009742	allantoate amidohydrolase; Region: AllC; TIGR03176
866768009743	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
866768009744	active site
866768009745	metal binding site [ion binding]; metal-binding site
866768009746	dimer interface [polypeptide binding]; other site
866768009747	Uncharacterized protein, possibly involved in glyoxylate utilization [General function prediction only]; Region: GlxB; COG3257
866768009748	Protein of unknown function (DUF861); Region: Cupin_3; pfam05899
866768009749	Cupin domain; Region: Cupin_2; cl17218
866768009750	glycerate kinase II; Provisional; Region: PRK09932
866768009751	putative uracil/xanthine transporter; Provisional; Region: PRK11412
866768009752	allantoinase; Provisional; Region: PRK08044
866768009753	L-Hydantoinases (L-HYDs) and Allantoinase (ALN); L-Hydantoinases are a member of the dihydropyrimidinase family, which catalyzes the reversible hydrolytic ring opening of dihydropyrimidines and hydantoins (five-membered cyclic diamides used in...; Region: L-HYD_ALN; cd01315
866768009754	active site
866768009755	nucleobase-cation-symport-1 (NCS1) transporters; solute-binding domain; Region: SLC-NCS1sbd; cd10323
866768009756	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
866768009757	Na binding site [ion binding]; other site
866768009758	substrate binding site [chemical binding]; other site
866768009759	tartronate semialdehyde reductase; Provisional; Region: PRK15059
866768009760	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
866768009761	hydroxypyruvate isomerase; Provisional; Region: PRK09997
866768009762	glyoxylate carboligase; Provisional; Region: PRK11269
866768009763	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
866768009764	PYR/PP interface [polypeptide binding]; other site
866768009765	dimer interface [polypeptide binding]; other site
866768009766	TPP binding site [chemical binding]; other site
866768009767	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
866768009768	Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the...; Region: TPP_Gcl; cd02006
866768009769	TPP-binding site [chemical binding]; other site
866768009770	DNA-binding transcriptional repressor AllR; Provisional; Region: PRK10163
866768009771	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
866768009772	Bacterial transcriptional regulator; Region: IclR; pfam01614
866768009773	Ureidoglycolate hydrolase [Nucleotide transport and metabolism]; Region: DAL3; COG3194
866768009774	ureidoglycolate hydrolase; Provisional; Region: PRK03606
866768009775	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
866768009776	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768009777	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
866768009778	dimerization interface [polypeptide binding]; other site
866768009779	Predicted ATPase [General function prediction only]; Region: COG2603
866768009780	Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB; Region: RHOD_YbbB; cd01520
866768009781	active site residue [active]
866768009782	Winged helix-turn helix; Region: HTH_29; pfam13551
866768009783	Helix-turn-helix domain; Region: HTH_28; pfam13518
866768009784	hypothetical protein; Provisional; Region: PRK14710
866768009785	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
866768009786	RHS protein; Region: RHS; pfam03527
866768009787	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
866768009788	PAAR motif; Region: PAAR_motif; cl15808
866768009789	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
866768009790	RHS Repeat; Region: RHS_repeat; pfam05593
866768009791	RHS Repeat; Region: RHS_repeat; pfam05593
866768009792	RHS Repeat; Region: RHS_repeat; pfam05593
866768009793	RHS Repeat; Region: RHS_repeat; pfam05593
866768009794	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
866768009795	RHS Repeat; Region: RHS_repeat; pfam05593
866768009796	RHS Repeat; Region: RHS_repeat; pfam05593
866768009797	RHS protein; Region: RHS; pfam03527
866768009798	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
866768009799	Domain of unknown function (DUF4329); Region: DUF4329; pfam14220
866768009800	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
866768009801	FtsX-like permease family; Region: FtsX; pfam02687
866768009802	FtsX-like permease family; Region: FtsX; pfam02687
866768009803	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
866768009804	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
866768009805	Walker A/P-loop; other site
866768009806	ATP binding site [chemical binding]; other site
866768009807	Q-loop/lid; other site
866768009808	ABC transporter signature motif; other site
866768009809	Walker B; other site
866768009810	D-loop; other site
866768009811	H-loop/switch region; other site
866768009812	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
866768009813	active site
866768009814	catalytic triad [active]
866768009815	oxyanion hole [active]
866768009816	switch loop; other site
866768009817	oxidoreductase; Provisional; Region: PRK08017
866768009818	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
866768009819	NADP binding site [chemical binding]; other site
866768009820	active site
866768009821	steroid binding site; other site
866768009822	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
866768009823	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
866768009824	Uncharacterized protein family (UPF0014); Region: UPF0014; pfam03649
866768009825	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
866768009826	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866768009827	Walker A/P-loop; other site
866768009828	ATP binding site [chemical binding]; other site
866768009829	Q-loop/lid; other site
866768009830	ABC transporter signature motif; other site
866768009831	Walker B; other site
866768009832	D-loop; other site
866768009833	H-loop/switch region; other site
866768009834	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
866768009835	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
866768009836	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
866768009837	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
866768009838	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
866768009839	DNA binding residues [nucleotide binding]
866768009840	dimer interface [polypeptide binding]; other site
866768009841	copper binding site [ion binding]; other site
866768009842	amino acid transporter; Region: 2A0306; TIGR00909
866768009843	glutaminase; Reviewed; Region: PRK12356
866768009844	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
866768009845	copper exporting ATPase; Provisional; Region: copA; PRK10671
866768009846	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
866768009847	metal-binding site [ion binding]
866768009848	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
866768009849	metal-binding site [ion binding]
866768009850	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
866768009851	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866768009852	motif II; other site
866768009853	Plasmid maintenance system antidote protein [General function prediction only]; Region: VapI; COG3093
866768009854	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
866768009855	non-specific DNA binding site [nucleotide binding]; other site
866768009856	salt bridge; other site
866768009857	sequence-specific DNA binding site [nucleotide binding]; other site
866768009858	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3735
866768009859	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
866768009860	putative deacylase active site [active]
866768009861	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
866768009862	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
866768009863	active site
866768009864	metal binding site [ion binding]; metal-binding site
866768009865	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
866768009866	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768009867	Major Facilitator Superfamily; Region: MFS_1; pfam07690
866768009868	putative substrate translocation pore; other site
866768009869	putative cation:proton antiport protein; Provisional; Region: PRK10669
866768009870	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
866768009871	TrkA-N domain; Region: TrkA_N; pfam02254
866768009872	inosine/guanosine kinase; Provisional; Region: PRK15074
866768009873	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
866768009874	acetyl esterase; Provisional; Region: PRK10162
866768009875	ferrochelatase; Region: hemH; TIGR00109
866768009876	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
866768009877	C-terminal domain interface [polypeptide binding]; other site
866768009878	active site
866768009879	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
866768009880	active site
866768009881	N-terminal domain interface [polypeptide binding]; other site
866768009882	adenylate kinase; Reviewed; Region: adk; PRK00279
866768009883	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
866768009884	AMP-binding site [chemical binding]; other site
866768009885	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
866768009886	heat shock protein 90; Provisional; Region: PRK05218
866768009887	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866768009888	ATP binding site [chemical binding]; other site
866768009889	Mg2+ binding site [ion binding]; other site
866768009890	G-X-G motif; other site
866768009891	Recombinational DNA repair protein (RecF pathway) [DNA replication, recombination, and repair]; Region: RecR; COG0353
866768009892	RecR protein; Region: RecR; pfam02132
866768009893	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
866768009894	putative active site [active]
866768009895	putative metal-binding site [ion binding]; other site
866768009896	tetramer interface [polypeptide binding]; other site
866768009897	hypothetical protein; Validated; Region: PRK00153
866768009898	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
866768009899	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866768009900	Walker A motif; other site
866768009901	ATP binding site [chemical binding]; other site
866768009902	Walker B motif; other site
866768009903	DNA polymerase III subunit delta'; Validated; Region: PRK08485
866768009904	arginine finger; other site
866768009905	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
866768009906	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
866768009907	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
866768009908	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
866768009909	active site
866768009910	hypothetical protein; Provisional; Region: PRK10527
866768009911	primosomal replication protein N''; Provisional; Region: PRK10093
866768009912	hypothetical protein; Provisional; Region: PRK11038
866768009913	hypothetical protein; Provisional; Region: PRK11281
866768009914	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
866768009915	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
866768009916	Mechanosensitive ion channel; Region: MS_channel; pfam00924
866768009917	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
866768009918	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
866768009919	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
866768009920	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
866768009921	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
866768009922	HlyD family secretion protein; Region: HlyD_3; pfam13437
866768009923	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
866768009924	Protein export membrane protein; Region: SecD_SecF; cl14618
866768009925	Protein export membrane protein; Region: SecD_SecF; cl14618
866768009926	Biofilm formation regulator YbaJ; Region: YbaJ; pfam10757
866768009927	gene expression modulator; Provisional; Region: PRK10945
866768009928	maltose O-acetyltransferase; Provisional; Region: PRK10092
866768009929	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
866768009930	active site
866768009931	substrate binding site [chemical binding]; other site
866768009932	trimer interface [polypeptide binding]; other site
866768009933	CoA binding site [chemical binding]; other site
866768009934	sigma70 family sigma factor YlaC; Region: YlaC; pfam10777
866768009935	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
866768009936	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
866768009937	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
866768009938	Uncharacterized conserved protein [Function unknown]; Region: COG5507
866768009939	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
866768009940	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
866768009941	DNA binding site [nucleotide binding]
866768009942	active site
866768009943	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
866768009944	acyl-CoA thioesterase II; Provisional; Region: PRK10526
866768009945	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
866768009946	active site
866768009947	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
866768009948	catalytic triad [active]
866768009949	dimer interface [polypeptide binding]; other site
866768009950	ammonium transporter; Provisional; Region: PRK10666
866768009951	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
866768009952	Nitrogen regulatory protein P-II; Region: P-II; smart00938
866768009953	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
866768009954	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
866768009955	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
866768009956	Walker A/P-loop; other site
866768009957	ATP binding site [chemical binding]; other site
866768009958	Q-loop/lid; other site
866768009959	ABC transporter signature motif; other site
866768009960	Walker B; other site
866768009961	D-loop; other site
866768009962	H-loop/switch region; other site
866768009963	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
866768009964	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
866768009965	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866768009966	Walker A/P-loop; other site
866768009967	ATP binding site [chemical binding]; other site
866768009968	Q-loop/lid; other site
866768009969	ABC transporter signature motif; other site
866768009970	Walker B; other site
866768009971	D-loop; other site
866768009972	H-loop/switch region; other site
866768009973	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
866768009974	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
866768009975	putative DNA binding site [nucleotide binding]; other site
866768009976	putative Zn2+ binding site [ion binding]; other site
866768009977	AsnC family; Region: AsnC_trans_reg; pfam01037
866768009978	thiamin pyrimidine pyrophosphate hydrolase; Provisional; Region: PRK15126
866768009979	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866768009980	active site
866768009981	motif I; other site
866768009982	motif II; other site
866768009983	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
866768009984	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
866768009985	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
866768009986	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
866768009987	Ligand Binding Site [chemical binding]; other site
866768009988	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
866768009989	active site
866768009990	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
866768009991	periplasmic folding chaperone; Provisional; Region: PRK10788
866768009992	SurA N-terminal domain; Region: SurA_N_3; cl07813
866768009993	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
866768009994	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
866768009995	IHF dimer interface [polypeptide binding]; other site
866768009996	IHF - DNA interface [nucleotide binding]; other site
866768009997	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
866768009998	Found in ATP-dependent protease La (LON); Region: LON; smart00464
866768009999	Found in ATP-dependent protease La (LON); Region: LON; smart00464
866768010000	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866768010001	Walker A motif; other site
866768010002	ATP binding site [chemical binding]; other site
866768010003	Walker B motif; other site
866768010004	arginine finger; other site
866768010005	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
866768010006	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
866768010007	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
866768010008	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
866768010009	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
866768010010	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866768010011	Walker A motif; other site
866768010012	ATP binding site [chemical binding]; other site
866768010013	Walker B motif; other site
866768010014	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
866768010015	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
866768010016	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
866768010017	oligomer interface [polypeptide binding]; other site
866768010018	active site residues [active]
866768010019	trigger factor; Provisional; Region: tig; PRK01490
866768010020	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
866768010021	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
866768010022	transcriptional regulator BolA; Provisional; Region: PRK11628
866768010023	hypothetical protein; Provisional; Region: PRK11627
866768010024	Uncharacterized lipoprotein; Region: Lipoprotein_16; pfam03923
866768010025	muropeptide transporter; Reviewed; Region: ampG; PRK11902
866768010026	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768010027	putative substrate translocation pore; other site
866768010028	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
866768010029	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
866768010030	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
866768010031	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
866768010032	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
866768010033	D-pathway; other site
866768010034	Putative ubiquinol binding site [chemical binding]; other site
866768010035	Low-spin heme (heme b) binding site [chemical binding]; other site
866768010036	Putative water exit pathway; other site
866768010037	Binuclear center (heme o3/CuB) [ion binding]; other site
866768010038	K-pathway; other site
866768010039	Putative proton exit pathway; other site
866768010040	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
866768010041	Subunit I/III interface [polypeptide binding]; other site
866768010042	Subunit III/IV interface [polypeptide binding]; other site
866768010043	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
866768010044	protoheme IX farnesyltransferase; Provisional; Region: PRK13362
866768010045	UbiA prenyltransferase family; Region: UbiA; pfam01040
866768010046	Protein of unknown function (DUF1778); Region: DUF1778; pfam08681
866768010047	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
866768010048	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
866768010049	Sel1 repeat; Region: Sel1; pfam08238
866768010050	Sel1-like repeats; Region: SEL1; smart00671
866768010051	Sel1-like repeats; Region: SEL1; smart00671
866768010052	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768010053	Major Facilitator Superfamily; Region: MFS_1; pfam07690
866768010054	putative substrate translocation pore; other site
866768010055	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
866768010056	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
866768010057	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
866768010058	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
866768010059	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
866768010060	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
866768010061	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
866768010062	conserved cys residue [active]
866768010063	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
866768010064	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
866768010065	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
866768010066	Ligand Binding Site [chemical binding]; other site
866768010067	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
866768010068	active site residue [active]
866768010069	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
866768010070	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
866768010071	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
866768010072	substrate binding pocket [chemical binding]; other site
866768010073	chain length determination region; other site
866768010074	substrate-Mg2+ binding site; other site
866768010075	catalytic residues [active]
866768010076	aspartate-rich region 1; other site
866768010077	active site lid residues [active]
866768010078	aspartate-rich region 2; other site
866768010079	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
866768010080	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
866768010081	TPP-binding site; other site
866768010082	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
866768010083	PYR/PP interface [polypeptide binding]; other site
866768010084	dimer interface [polypeptide binding]; other site
866768010085	TPP binding site [chemical binding]; other site
866768010086	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
866768010087	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
866768010088	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
866768010089	active site
866768010090	catalytic tetrad [active]
866768010091	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
866768010092	tetramer interfaces [polypeptide binding]; other site
866768010093	binuclear metal-binding site [ion binding]; other site
866768010094	thiamine monophosphate kinase; Provisional; Region: PRK05731
866768010095	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
866768010096	ATP binding site [chemical binding]; other site
866768010097	dimerization interface [polypeptide binding]; other site
866768010098	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
866768010099	putative RNA binding site [nucleotide binding]; other site
866768010100	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
866768010101	homopentamer interface [polypeptide binding]; other site
866768010102	active site
866768010103	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
866768010104	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
866768010105	catalytic motif [active]
866768010106	Zn binding site [ion binding]; other site
866768010107	riboflavin-specific deaminase C-terminal domain; Region: ribD_Cterm; TIGR00227
866768010108	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
866768010109	ATP cone domain; Region: ATP-cone; pfam03477
866768010110	hypothetical protein; Provisional; Region: PRK11530
866768010111	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
866768010112	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
866768010113	active site
866768010114	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
866768010115	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
866768010116	Protein export membrane protein; Region: SecD_SecF; pfam02355
866768010117	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
866768010118	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
866768010119	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
866768010120	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
866768010121	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
866768010122	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
866768010123	tRNA-guanine family transglycosylase; Region: tgt_general; TIGR00449
866768010124	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
866768010125	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
866768010126	acyl carrier protein phosphodiesterase; Provisional; Region: PRK10045
866768010127	maltodextrin glucosidase; Provisional; Region: PRK10785
866768010128	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
866768010129	homodimer interface [polypeptide binding]; other site
866768010130	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
866768010131	active site
866768010132	homodimer interface [polypeptide binding]; other site
866768010133	catalytic site [active]
866768010134	putative proline-specific permease; Provisional; Region: proY; PRK10580
866768010135	Spore germination protein; Region: Spore_permease; cl17796
866768010136	branched-chain amino acid transport system 2 carrier protein BrnQ; Provisional; Region: PRK15433
866768010137	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
866768010138	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
866768010139	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
866768010140	putative active site [active]
866768010141	heme pocket [chemical binding]; other site
866768010142	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
866768010143	dimer interface [polypeptide binding]; other site
866768010144	phosphorylation site [posttranslational modification]
866768010145	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866768010146	ATP binding site [chemical binding]; other site
866768010147	Mg2+ binding site [ion binding]; other site
866768010148	G-X-G motif; other site
866768010149	transcriptional regulator PhoB; Provisional; Region: PRK10161
866768010150	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768010151	active site
866768010152	phosphorylation site [posttranslational modification]
866768010153	intermolecular recognition site; other site
866768010154	dimerization interface [polypeptide binding]; other site
866768010155	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
866768010156	DNA binding site [nucleotide binding]
866768010157	exonuclease subunit SbcD; Provisional; Region: PRK10966
866768010158	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
866768010159	active site
866768010160	metal binding site [ion binding]; metal-binding site
866768010161	DNA binding site [nucleotide binding]
866768010162	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
866768010163	exonuclease subunit SbcC; Provisional; Region: PRK10246
866768010164	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866768010165	Walker A/P-loop; other site
866768010166	ATP binding site [chemical binding]; other site
866768010167	Q-loop/lid; other site
866768010168	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866768010169	ABC transporter signature motif; other site
866768010170	Walker B; other site
866768010171	D-loop; other site
866768010172	H-loop/switch region; other site
866768010173	MFS transport protein AraJ; Provisional; Region: PRK10091
866768010174	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768010175	putative substrate translocation pore; other site
866768010176	Protein of unknown function (DUF3521); Region: DUF3521; pfam12035
866768010177	fructokinase; Reviewed; Region: PRK09557
866768010178	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
866768010179	nucleotide binding site [chemical binding]; other site
866768010180	DNA recombination-dependent growth factor C [DNA replication, recombination, and repair]; Region: RdgC; COG2974
866768010181	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
866768010182	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
866768010183	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
866768010184	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
866768010185	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
866768010186	hypothetical protein; Provisional; Region: PRK10579
866768010187	hypothetical protein; Provisional; Region: PRK10481
866768010188	hypothetical protein; Provisional; Region: PRK10380
866768010189	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
866768010190	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
866768010191	ADP binding site [chemical binding]; other site
866768010192	magnesium binding site [ion binding]; other site
866768010193	putative shikimate binding site; other site
866768010194	hypothetical protein; Validated; Region: PRK00124
866768010195	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
866768010196	pyrroline-5-carboxylate reductase; Region: PLN02688
866768010197	diguanylate cyclase AdrA; Provisional; Region: adrA; PRK10245
866768010198	MASE2 domain; Region: MASE2; pfam05230
866768010199	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
866768010200	metal binding site [ion binding]; metal-binding site
866768010201	active site
866768010202	I-site; other site
866768010203	hypothetical protein; Provisional; Region: PRK11505
866768010204	psiF repeat; Region: PsiF_repeat; pfam07769
866768010205	psiF repeat; Region: PsiF_repeat; pfam07769
866768010206	alkaline phosphatase; Provisional; Region: PRK10518
866768010207	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016
866768010208	dimer interface [polypeptide binding]; other site
866768010209	active site
866768010210	anti-RssB factor; Provisional; Region: PRK10244
866768010211	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
866768010212	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
866768010213	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
866768010214	Protein of unknown function (DUF2754); Region: DUF2754; pfam10953
866768010215	Protein of unknown function (DUF2755); Region: DUF2755; pfam10954
866768010216	Protein of unknown function (DUF1615); Region: DUF1615; pfam07759
866768010217	microcin B17 transporter; Reviewed; Region: PRK11098
866768010218	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
866768010219	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
866768010220	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
866768010221	Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain...; Region: PL_Passenger_AT; cd00253
866768010222	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
866768010223	Autotransporter beta-domain; Region: Autotransporter; pfam03797
866768010224	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
866768010225	dimer interface [polypeptide binding]; other site
866768010226	active site
866768010227	Schiff base residues; other site
866768010228	Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175
866768010229	taurine dioxygenase; Reviewed; Region: tauD; PRK09553
866768010230	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
866768010231	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768010232	dimer interface [polypeptide binding]; other site
866768010233	conserved gate region; other site
866768010234	putative PBP binding loops; other site
866768010235	ABC-ATPase subunit interface; other site
866768010236	taurine transporter ATP-binding subunit; Provisional; Region: tauB; PRK11248
866768010237	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
866768010238	Walker A/P-loop; other site
866768010239	ATP binding site [chemical binding]; other site
866768010240	Q-loop/lid; other site
866768010241	ABC transporter signature motif; other site
866768010242	Walker B; other site
866768010243	D-loop; other site
866768010244	H-loop/switch region; other site
866768010245	ABC-type taurine transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: TauA; COG4521
866768010246	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
866768010247	substrate binding pocket [chemical binding]; other site
866768010248	membrane-bound complex binding site; other site
866768010249	hinge residues; other site
866768010250	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
866768010251	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
866768010252	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
866768010253	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
866768010254	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
866768010255	putative metal binding site [ion binding]; other site
866768010256	putative homodimer interface [polypeptide binding]; other site
866768010257	putative homotetramer interface [polypeptide binding]; other site
866768010258	putative homodimer-homodimer interface [polypeptide binding]; other site
866768010259	putative allosteric switch controlling residues; other site
866768010260	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
866768010261	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
866768010262	substrate binding site [chemical binding]; other site
866768010263	catalytic Zn binding site [ion binding]; other site
866768010264	NAD binding site [chemical binding]; other site
866768010265	structural Zn binding site [ion binding]; other site
866768010266	dimer interface [polypeptide binding]; other site
866768010267	S-formylglutathione hydrolase; Region: fghA_ester_D; TIGR02821
866768010268	S-formylglutathione hydrolase; Region: PLN02442
866768010269	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
866768010270	putative 3-hydroxyphenylpropionic transporter MhpT; Provisional; Region: PRK11551
866768010271	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768010272	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768010273	4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase,; Validated; Region: PRK08195
866768010274	4-hydroxy-2-oxovalerate aldolase, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_HOA; cd07943
866768010275	active site
866768010276	catalytic residues [active]
866768010277	metal binding site [ion binding]; metal-binding site
866768010278	DmpG-like communication domain; Region: DmpG_comm; pfam07836
866768010279	acetaldehyde dehydrogenase; Validated; Region: PRK08300
866768010280	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
866768010281	Prokaryotic acetaldehyde dehydrogenase, dimerisation; Region: AcetDehyd-dimer; pfam09290
866768010282	2-keto-4-pentenoate hydratase; Provisional; Region: mhpD; PRK11342
866768010283	2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; Region: biphenyl_bphD; TIGR03343
866768010284	Subunit B of the Class III Extradiol ring-cleavage dioxygenase, 2,3-dihydroxyphenylpropionate 1,2-dioxygenase (MhpB), which catalyzes the oxidization and subsequent ring-opening of 2,3-dihydroxyphenylpropionate; Region: MhpB_like; cd07365
866768010285	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
866768010286	putative active site [active]
866768010287	Fe(II) binding site [ion binding]; other site
866768010288	putative dimer interface [polypeptide binding]; other site
866768010289	putative tetramer interface [polypeptide binding]; other site
866768010290	3-(3-hydroxyphenyl)propionate hydroxylase; Validated; Region: mhpA; PRK06183
866768010291	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
866768010292	DNA-binding transcriptional activator MhpR; Provisional; Region: PRK09834
866768010293	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
866768010294	Bacterial transcriptional regulator; Region: IclR; pfam01614
866768010295	lac repressor; Reviewed; Region: lacI; PRK09526
866768010296	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
866768010297	DNA binding site [nucleotide binding]
866768010298	domain linker motif; other site
866768010299	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
866768010300	ligand binding site [chemical binding]; other site
866768010301	dimerization interface (open form) [polypeptide binding]; other site
866768010302	dimerization interface (closed form) [polypeptide binding]; other site
866768010303	beta-D-galactosidase; Reviewed; Region: lacZ; PRK09525
866768010304	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
866768010305	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
866768010306	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
866768010307	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
866768010308	LacY proton/sugar symporter; Region: LacY_symp; pfam01306
866768010309	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768010310	putative substrate translocation pore; other site
866768010311	galactoside O-acetyltransferase; Reviewed; Region: lacA; PRK09527
866768010312	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
866768010313	active site
866768010314	substrate binding site [chemical binding]; other site
866768010315	trimer interface [polypeptide binding]; other site
866768010316	CoA binding site [chemical binding]; other site
866768010317	putative cyanate transporter; Provisional; Region: cynX; PRK09705
866768010318	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768010319	Cyanate lyase [Inorganic ion transport and metabolism]; Region: CynS; COG1513
866768010320	Cyanase C-terminal domain. Cyanase (Cyanate lyase) is responsible for the hydrolysis of cyanate.  It catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. This allows organisms that possess the enzyme to overcome the...; Region: Cyanase_C; cd00559
866768010321	oligomer interface [polypeptide binding]; other site
866768010322	active site
866768010323	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
866768010324	active site clefts [active]
866768010325	zinc binding site [ion binding]; other site
866768010326	dimer interface [polypeptide binding]; other site
866768010327	DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242
866768010328	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768010329	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator CynR, contains the type 2 periplasmic binding fold; Region: PBP2_CynR; cd08425
866768010330	dimerization interface [polypeptide binding]; other site
866768010331	cytosine deaminase; Provisional; Region: PRK09230
866768010332	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
866768010333	active site
866768010334	nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; Region: SLC-NCS1sbd_CobB-like; cd11484
866768010335	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
866768010336	Na binding site [ion binding]; other site
866768010337	putative substrate binding site [chemical binding]; other site
866768010338	propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524
866768010339	Propionyl-CoA synthetase (PrpE); Region: PrpE; cd05967
866768010340	acyl-activating enzyme (AAE) consensus motif; other site
866768010341	putative AMP binding site [chemical binding]; other site
866768010342	putative active site [active]
866768010343	putative CoA binding site [chemical binding]; other site
866768010344	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
866768010345	2-methylcitrate dehydratase; Region: prpD; TIGR02330
866768010346	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
866768010347	Subgroup of Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS)...; Region: Ec2MCS_like_1; cd06117
866768010348	dimer interface [polypeptide binding]; other site
866768010349	active site
866768010350	citrylCoA binding site [chemical binding]; other site
866768010351	oxalacetate/citrate binding site [chemical binding]; other site
866768010352	coenzyme A binding site [chemical binding]; other site
866768010353	catalytic triad [active]
866768010354	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
866768010355	Phosphoenolpyruvate phosphomutase; Region: PEP_mutase; pfam13714
866768010356	tetramer interface [polypeptide binding]; other site
866768010357	active site
866768010358	Mg2+/Mn2+ binding site [ion binding]; other site
866768010359	propionate catabolism operon regulatory protein PrpR; Provisional; Region: PRK15424
866768010360	Propionate catabolism activator; Region: PrpR_N; pfam06506
866768010361	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866768010362	Walker A motif; other site
866768010363	ATP binding site [chemical binding]; other site
866768010364	Walker B motif; other site
866768010365	arginine finger; other site
866768010366	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
866768010367	hypothetical protein; Provisional; Region: PRK09929
866768010368	The Resistance to Homoserine/Threonine (RhtB) Family protein; Region: 2A76; TIGR00949
866768010369	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
866768010370	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
866768010371	putative NAD(P) binding site [chemical binding]; other site
866768010372	putative substrate binding site [chemical binding]; other site
866768010373	catalytic Zn binding site [ion binding]; other site
866768010374	structural Zn binding site [ion binding]; other site
866768010375	dimer interface [polypeptide binding]; other site
866768010376	putative deaminase; Validated; Region: PRK06846
866768010377	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
866768010378	active site
866768010379	carbamate kinase-like carbamoyl phosphate synthetase; Reviewed; Region: PRK12454
866768010380	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
866768010381	putative substrate binding site [chemical binding]; other site
866768010382	nucleotide binding site [chemical binding]; other site
866768010383	nucleotide binding site [chemical binding]; other site
866768010384	homodimer interface [polypeptide binding]; other site
866768010385	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
866768010386	Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Region: SucD; COG0074
866768010387	CoA binding domain; Region: CoA_binding; pfam02629
866768010388	CoA-ligase; Region: Ligase_CoA; pfam00549
866768010389	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
866768010390	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
866768010391	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
866768010392	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
866768010393	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
866768010394	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
866768010395	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768010396	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
866768010397	dimerization interface [polypeptide binding]; other site
866768010398	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
866768010399	DNA binding residues [nucleotide binding]
866768010400	dimerization interface [polypeptide binding]; other site
866768010401	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
866768010402	choline transport protein BetT; Provisional; Region: PRK09928
866768010403	transcriptional regulator BetI; Validated; Region: PRK00767
866768010404	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
866768010405	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
866768010406	betaine aldehyde dehydrogenase; Provisional; Region: PRK13252
866768010407	NAD+-dependent 4-trimethylaminobutyraldehyde dehydrogenase, ALDH family 9A1; Region: ALDH_F9_TMBADH; cd07090
866768010408	tetrameric interface [polypeptide binding]; other site
866768010409	NAD binding site [chemical binding]; other site
866768010410	catalytic residues [active]
866768010411	choline dehydrogenase; Validated; Region: PRK02106
866768010412	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
866768010413	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
866768010414	Uncharacterized conserved protein [Function unknown]; Region: COG1556
866768010415	iron-sulfur cluster-binding protein; Region: TIGR00273
866768010416	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
866768010417	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
866768010418	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
866768010419	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
866768010420	Cysteine-rich domain; Region: CCG; pfam02754
866768010421	Cysteine-rich domain; Region: CCG; pfam02754
866768010422	Cupin; Region: Cupin_6; pfam12852
866768010423	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
866768010424	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768010425	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK08010
866768010426	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
866768010427	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
866768010428	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
866768010429	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
866768010430	Predicted membrane protein [Function unknown]; Region: COG3059
866768010431	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
866768010432	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768010433	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
866768010434	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
866768010435	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
866768010436	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
866768010437	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
866768010438	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
866768010439	DNA binding residues [nucleotide binding]
866768010440	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
866768010441	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
866768010442	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
866768010443	Predicted periplasmic/secreted protein [Function unknown]; Region: COG3477
866768010444	aldehyde oxidoreductase 2Fe-2S subunit; Provisional; Region: PRK11433
866768010445	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
866768010446	catalytic loop [active]
866768010447	iron binding site [ion binding]; other site
866768010448	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
866768010449	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]; Region: CoxM; COG1319
866768010450	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; smart01092
866768010451	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
866768010452	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
866768010453	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
866768010454	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
866768010455	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
866768010456	XdhC Rossmann domain; Region: XdhC_C; pfam13478
866768010457	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
866768010458	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
866768010459	Transcriptional regulator [Transcription]; Region: LysR; COG0583
866768010460	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
866768010461	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
866768010462	putative catalytic cysteine [active]
866768010463	gamma-glutamyl kinase; Provisional; Region: PRK05429
866768010464	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
866768010465	nucleotide binding site [chemical binding]; other site
866768010466	homotetrameric interface [polypeptide binding]; other site
866768010467	putative phosphate binding site [ion binding]; other site
866768010468	putative allosteric binding site; other site
866768010469	PUA domain; Region: PUA; pfam01472
866768010470	Outer membrane protein (porin) [Cell envelope biogenesis, outer membrane]; Region: OmpC; COG3203
866768010471	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
866768010472	trimer interface [polypeptide binding]; other site
866768010473	eyelet of channel; other site
866768010474	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
866768010475	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
866768010476	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
866768010477	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
866768010478	DNA-binding transcriptional regulator Crl; Provisional; Region: PRK10984
866768010479	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
866768010480	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
866768010481	active site
866768010482	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
866768010483	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
866768010484	metal binding site [ion binding]; metal-binding site
866768010485	dimer interface [polypeptide binding]; other site
866768010486	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
866768010487	peptide chain release factor-like protein; Reviewed; Region: prfH; PRK08179
866768010488	Uncharacterized protein family UPF0027; Region: UPF0027; cl17455
866768010489	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
866768010490	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
866768010491	Coenzyme A binding pocket [chemical binding]; other site
866768010492	putative toxin YafO; Provisional; Region: PRK09885
866768010493	putative antitoxin of the YafO-YafN toxin-antitoxin system; Provisional; Region: PRK09778
866768010494	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
866768010495	active site
866768010496	DNA polymerase IV; Validated; Region: PRK02406
866768010497	DNA binding site [nucleotide binding]
866768010498	hypothetical protein; Validated; Region: PRK06778
866768010499	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
866768010500	ligand binding site [chemical binding]; other site
866768010501	Flagellar biosynthesis pathway, component FlhA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlhA; COG1298
866768010502	FHIPEP family; Region: FHIPEP; pfam00771
866768010503	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG1943
866768010504	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
866768010505	NlpC/P60 family; Region: NLPC_P60; pfam00877
866768010506	RelB antitoxin; Region: RelB; cl01171
866768010507	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041
866768010508	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
866768010509	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
866768010510	Predicted glutamine amidotransferase [General function prediction only]; Region: COG0121
866768010511	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
866768010512	putative active site [active]
866768010513	putative dimer interface [polypeptide binding]; other site
866768010514	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
866768010515	dimer interface [polypeptide binding]; other site
866768010516	active site
866768010517	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
866768010518	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
866768010519	active site
866768010520	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
866768010521	C-lysozyme inhibitor; Provisional; Region: PRK09993
866768010522	C-N hydrolase family amidase; Provisional; Region: PRK10438
866768010523	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
866768010524	putative active site [active]
866768010525	catalytic triad [active]
866768010526	dimer interface [polypeptide binding]; other site
866768010527	multimer interface [polypeptide binding]; other site
866768010528	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
866768010529	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
866768010530	Transposase [DNA replication, recombination, and repair]; Region: COG5433
866768010531	Transposase [DNA replication, recombination, and repair]; Region: COG5433
866768010532	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
866768010533	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
866768010534	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
866768010535	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
866768010536	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
866768010537	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
866768010538	active site
866768010539	catalytic site [active]
866768010540	substrate binding site [chemical binding]; other site
866768010541	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
866768010542	RNA/DNA hybrid binding site [nucleotide binding]; other site
866768010543	active site
866768010544	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768010545	hydroxyacylglutathione hydrolase; Provisional; Region: PRK10241
866768010546	membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783
866768010547	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
866768010548	N-acetyl-D-glucosamine binding site [chemical binding]; other site
866768010549	catalytic residue [active]
866768010550	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
866768010551	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
866768010552	Methyltransferase domain; Region: Methyltransf_31; pfam13847
866768010553	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768010554	hypothetical protein; Provisional; Region: PRK05421
866768010555	putative catalytic site [active]
866768010556	putative metal binding site [ion binding]; other site
866768010557	putative phosphate binding site [ion binding]; other site
866768010558	putative catalytic site [active]
866768010559	putative phosphate binding site [ion binding]; other site
866768010560	putative metal binding site [ion binding]; other site
866768010561	Transcriptional regulator [Transcription]; Region: LysR; COG0583
866768010562	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768010563	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA; cd08478
866768010564	putative effector binding pocket; other site
866768010565	dimerization interface [polypeptide binding]; other site
866768010566	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
866768010567	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
866768010568	active site
866768010569	catalytic tetrad [active]
866768010570	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
866768010571	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866768010572	active site
866768010573	motif I; other site
866768010574	motif II; other site
866768010575	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
866768010576	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
866768010577	Walker A/P-loop; other site
866768010578	ATP binding site [chemical binding]; other site
866768010579	Q-loop/lid; other site
866768010580	ABC transporter signature motif; other site
866768010581	Walker B; other site
866768010582	D-loop; other site
866768010583	H-loop/switch region; other site
866768010584	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
866768010585	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768010586	dimer interface [polypeptide binding]; other site
866768010587	conserved gate region; other site
866768010588	ABC-ATPase subunit interface; other site
866768010589	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
866768010590	lipoprotein, YaeC family; Region: TIGR00363
866768010591	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
866768010592	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
866768010593	homodimer interaction site [polypeptide binding]; other site
866768010594	cofactor binding site; other site
866768010595	prolyl-tRNA synthetase; Provisional; Region: PRK09194
866768010596	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
866768010597	dimer interface [polypeptide binding]; other site
866768010598	motif 1; other site
866768010599	active site
866768010600	motif 2; other site
866768010601	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
866768010602	putative deacylase active site [active]
866768010603	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
866768010604	active site
866768010605	motif 3; other site
866768010606	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
866768010607	anticodon binding site; other site
866768010608	hypothetical protein; Provisional; Region: PRK11479
866768010609	Orthopoxvirus protein of unknown function (DUF830); Region: DUF830; cl13998
866768010610	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
866768010611	NlpE N-terminal domain; Region: NlpE; pfam04170
866768010612	hypothetical protein; Provisional; Region: PRK09256
866768010613	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
866768010614	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
866768010615	hypothetical protein; Provisional; Region: PRK04964
866768010616	Rho-binding antiterminator; Provisional; Region: PRK11625
866768010617	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
866768010618	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
866768010619	Ligand Binding Site [chemical binding]; other site
866768010620	TilS substrate binding domain; Region: TilS; pfam09179
866768010621	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
866768010622	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
866768010623	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
866768010624	putative metal binding site [ion binding]; other site
866768010625	lysine decarboxylase LdcC; Provisional; Region: PRK15399
866768010626	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
866768010627	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
866768010628	homodimer interface [polypeptide binding]; other site
866768010629	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768010630	catalytic residue [active]
866768010631	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
866768010632	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
866768010633	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
866768010634	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
866768010635	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
866768010636	putative active site [active]
866768010637	putative PHP Thumb interface [polypeptide binding]; other site
866768010638	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
866768010639	generic binding surface II; other site
866768010640	generic binding surface I; other site
866768010641	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
866768010642	RNA/DNA hybrid binding site [nucleotide binding]; other site
866768010643	active site
866768010644	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
866768010645	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
866768010646	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
866768010647	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
866768010648	active site
866768010649	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
866768010650	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
866768010651	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
866768010652	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
866768010653	trimer interface [polypeptide binding]; other site
866768010654	active site
866768010655	UDP-GlcNAc binding site [chemical binding]; other site
866768010656	lipid binding site [chemical binding]; lipid-binding site
866768010657	periplasmic chaperone; Provisional; Region: PRK10780
866768010658	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
866768010659	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
866768010660	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
866768010661	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
866768010662	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
866768010663	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
866768010664	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
866768010665	Surface antigen; Region: Bac_surface_Ag; pfam01103
866768010666	zinc metallopeptidase RseP; Provisional; Region: PRK10779
866768010667	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
866768010668	active site
866768010669	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
866768010670	protein binding site [polypeptide binding]; other site
866768010671	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
866768010672	putative substrate binding region [chemical binding]; other site
866768010673	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
866768010674	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
866768010675	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
866768010676	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
866768010677	catalytic residue [active]
866768010678	putative FPP diphosphate  binding site; other site
866768010679	putative FPP binding hydrophobic cleft; other site
866768010680	dimer interface [polypeptide binding]; other site
866768010681	putative IPP diphosphate binding site; other site
866768010682	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
866768010683	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
866768010684	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
866768010685	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
866768010686	ribosome recycling factor; Reviewed; Region: frr; PRK00083
866768010687	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
866768010688	hinge region; other site
866768010689	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
866768010690	putative nucleotide binding site [chemical binding]; other site
866768010691	uridine monophosphate binding site [chemical binding]; other site
866768010692	homohexameric interface [polypeptide binding]; other site
866768010693	elongation factor Ts; Provisional; Region: tsf; PRK09377
866768010694	UBA/TS-N domain; Region: UBA; pfam00627
866768010695	Elongation factor TS; Region: EF_TS; pfam00889
866768010696	Elongation factor TS; Region: EF_TS; pfam00889
866768010697	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
866768010698	rRNA interaction site [nucleotide binding]; other site
866768010699	S8 interaction site; other site
866768010700	putative laminin-1 binding site; other site
866768010701	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
866768010702	active site
866768010703	PII uridylyl-transferase; Provisional; Region: PRK05007
866768010704	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
866768010705	metal binding triad; other site
866768010706	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
866768010707	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
866768010708	Zn2+ binding site [ion binding]; other site
866768010709	Mg2+ binding site [ion binding]; other site
866768010710	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
866768010711	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
866768010712	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
866768010713	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
866768010714	trimer interface [polypeptide binding]; other site
866768010715	active site
866768010716	substrate binding site [chemical binding]; other site
866768010717	CoA binding site [chemical binding]; other site
866768010718	phosphodiesterase YaeI; Provisional; Region: PRK11340
866768010719	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
866768010720	putative active site [active]
866768010721	putative metal binding site [ion binding]; other site
866768010722	hypothetical protein; Provisional; Region: PRK13677
866768010723	carbohydrate diacid transcriptional activator CdaR; Provisional; Region: PRK11477
866768010724	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
866768010725	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
866768010726	serine endoprotease; Provisional; Region: PRK10942
866768010727	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
866768010728	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
866768010729	protein binding site [polypeptide binding]; other site
866768010730	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
866768010731	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
866768010732	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
866768010733	Zn2+ binding site [ion binding]; other site
866768010734	Mg2+ binding site [ion binding]; other site
866768010735	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
866768010736	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
866768010737	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
866768010738	vitamin B12-transporter protein BtuF; Provisional; Region: PRK03379
866768010739	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
866768010740	cobalamin binding residues [chemical binding]; other site
866768010741	putative BtuC binding residues; other site
866768010742	dimer interface [polypeptide binding]; other site
866768010743	hypothetical protein; Provisional; Region: PRK10578
866768010744	UPF0126 domain; Region: UPF0126; pfam03458
866768010745	UPF0126 domain; Region: UPF0126; pfam03458
866768010746	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
866768010747	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
866768010748	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
866768010749	Cl- selectivity filter; other site
866768010750	Cl- binding residues [ion binding]; other site
866768010751	pore gating glutamate residue; other site
866768010752	dimer interface [polypeptide binding]; other site
866768010753	H+/Cl- coupling transport residue; other site
866768010754	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
866768010755	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
866768010756	inhibitor-cofactor binding pocket; inhibition site
866768010757	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768010758	catalytic residue [active]
866768010759	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
866768010760	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
866768010761	ABC-ATPase subunit  interface; other site
866768010762	dimer interface [polypeptide binding]; other site
866768010763	putative PBP binding regions; other site
866768010764	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
866768010765	ABC-ATPase subunit  interface; other site
866768010766	dimer interface [polypeptide binding]; other site
866768010767	putative PBP binding regions; other site
866768010768	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
866768010769	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
866768010770	siderophore binding site; other site
866768010771	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
866768010772	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
866768010773	Walker A/P-loop; other site
866768010774	ATP binding site [chemical binding]; other site
866768010775	Q-loop/lid; other site
866768010776	ABC transporter signature motif; other site
866768010777	Walker B; other site
866768010778	D-loop; other site
866768010779	H-loop/switch region; other site
866768010780	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
866768010781	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
866768010782	Transglycosylase; Region: Transgly; pfam00912
866768010783	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
866768010784	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
866768010785	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
866768010786	ATP binding site [chemical binding]; other site
866768010787	putative Mg++ binding site [ion binding]; other site
866768010788	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
866768010789	nucleotide binding region [chemical binding]; other site
866768010790	ATP-binding site [chemical binding]; other site
866768010791	Helicase associated domain (HA2) Add an annotation; Region: HA2; smart00847
866768010792	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
866768010793	2'-5' RNA ligase; Provisional; Region: PRK15124
866768010794	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
866768010795	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
866768010796	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
866768010797	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
866768010798	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
866768010799	tRNA synthetases class I (E and Q), catalytic domain; Region: tRNA-synt_1c; pfam00749
866768010800	active site
866768010801	nucleotide binding site [chemical binding]; other site
866768010802	HIGH motif; other site
866768010803	KMSKS motif; other site
866768010804	poly(A) polymerase I; Provisional; Region: pcnB; PRK11623
866768010805	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
866768010806	active site
866768010807	NTP binding site [chemical binding]; other site
866768010808	metal binding triad [ion binding]; metal-binding site
866768010809	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
866768010810	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
866768010811	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
866768010812	catalytic center binding site [active]
866768010813	ATP binding site [chemical binding]; other site
866768010814	Fimbrial protein; Region: Fimbrial; cl01416
866768010815	putative chaperone protein EcpD; Provisional; Region: PRK09926
866768010816	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
866768010817	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
866768010818	putative fimbrial outer membrane usher protein; Provisional; Region: PRK09828
866768010819	PapC N-terminal domain; Region: PapC_N; pfam13954
866768010820	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
866768010821	PapC C-terminal domain; Region: PapC_C; pfam13953
866768010822	Fimbrial protein; Region: Fimbrial; cl01416
866768010823	putative fimbrial protein StaE; Provisional; Region: PRK15263
866768010824	putative fimbrial protein StaF; Provisional; Region: PRK15262
866768010825	putative fimbrial-like adhesin protein; Provisional; Region: PRK09723
866768010826	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
866768010827	oligomerization interface [polypeptide binding]; other site
866768010828	active site
866768010829	metal binding site [ion binding]; metal-binding site
866768010830	pantoate--beta-alanine ligase; Region: panC; TIGR00018
866768010831	Pantoate-beta-alanine ligase; Region: PanC; cd00560
866768010832	active site
866768010833	ATP-binding site [chemical binding]; other site
866768010834	pantoate-binding site; other site
866768010835	HXXH motif; other site
866768010836	Uncharacterized conserved protein [Function unknown]; Region: COG5464
866768010837	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
866768010838	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
866768010839	tetramerization interface [polypeptide binding]; other site
866768010840	active site
866768010841	Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins; Region: CE4_yadE_5s; cd10966
866768010842	putative active site [active]
866768010843	putative metal binding site [ion binding]; other site
866768010844	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
866768010845	active pocket/dimerization site; other site
866768010846	active site
866768010847	phosphorylation site [posttranslational modification]
866768010848	inner membrane transport permease; Provisional; Region: PRK15066
866768010849	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
866768010850	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
866768010851	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
866768010852	Walker A/P-loop; other site
866768010853	ATP binding site [chemical binding]; other site
866768010854	Q-loop/lid; other site
866768010855	ABC transporter signature motif; other site
866768010856	Walker B; other site
866768010857	D-loop; other site
866768010858	H-loop/switch region; other site
866768010859	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
866768010860	active site clefts [active]
866768010861	zinc binding site [ion binding]; other site
866768010862	dimer interface [polypeptide binding]; other site
866768010863	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
866768010864	active site
866768010865	membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Region: PQQ_membr_DH; TIGR03074
866768010866	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
866768010867	Trp docking motif [polypeptide binding]; other site
866768010868	putative active site [active]
866768010869	multicopper oxidase; Provisional; Region: PRK10965
866768010870	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
866768010871	Multicopper oxidase; Region: Cu-oxidase; pfam00394
866768010872	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
866768010873	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
866768010874	spermidine synthase; Provisional; Region: PRK00811
866768010875	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768010876	S-adenosylmethionine binding site [chemical binding]; other site
866768010877	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
866768010878	hypothetical protein; Provisional; Region: PRK05248
866768010879	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
866768010880	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
866768010881	substrate binding site [chemical binding]; other site
866768010882	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
866768010883	substrate binding site [chemical binding]; other site
866768010884	ligand binding site [chemical binding]; other site
866768010885	Protein of unknown function (DUF3300); Region: DUF3300; pfam11737
866768010886	Protein of unknown function (DUF3106); Region: DUF3106; pfam11304
866768010887	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cl01482
866768010888	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
866768010889	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
866768010890	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
866768010891	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
866768010892	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
866768010893	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
866768010894	E3 interaction surface; other site
866768010895	lipoyl attachment site [posttranslational modification]; other site
866768010896	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
866768010897	E3 interaction surface; other site
866768010898	lipoyl attachment site [posttranslational modification]; other site
866768010899	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
866768010900	E3 interaction surface; other site
866768010901	lipoyl attachment site [posttranslational modification]; other site
866768010902	e3 binding domain; Region: E3_binding; pfam02817
866768010903	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
866768010904	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
866768010905	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
866768010906	dimer interface [polypeptide binding]; other site
866768010907	TPP-binding site [chemical binding]; other site
866768010908	Transcriptional regulators [Transcription]; Region: FadR; COG2186
866768010909	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
866768010910	DNA-binding site [nucleotide binding]; DNA binding site
866768010911	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
866768010912	aromatic amino acid transporter; Provisional; Region: PRK10238
866768010913	regulatory protein AmpE; Provisional; Region: PRK10987
866768010914	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
866768010915	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
866768010916	amidase catalytic site [active]
866768010917	Zn binding residues [ion binding]; other site
866768010918	substrate binding site [chemical binding]; other site
866768010919	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
866768010920	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
866768010921	dimerization interface [polypeptide binding]; other site
866768010922	active site
866768010923	putative major pilin subunit; Provisional; Region: PRK10574
866768010924	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
866768010925	Pilin (bacterial filament); Region: Pilin; pfam00114
866768010926	hypothetical protein; Provisional; Region: PRK10436
866768010927	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
866768010928	Walker A motif; other site
866768010929	ATP binding site [chemical binding]; other site
866768010930	Walker B motif; other site
866768010931	type IV pilin biogenesis protein; Provisional; Region: PRK10573
866768010932	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
866768010933	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
866768010934	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
866768010935	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
866768010936	active site
866768010937	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
866768010938	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
866768010939	CoA-binding site [chemical binding]; other site
866768010940	ATP-binding [chemical binding]; other site
866768010941	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4582
866768010942	DNA gyrase inhibitor; Reviewed; Region: PRK00418
866768010943	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
866768010944	active site
866768010945	8-oxo-dGMP binding site [chemical binding]; other site
866768010946	nudix motif; other site
866768010947	metal binding site [ion binding]; metal-binding site
866768010948	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
866768010949	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
866768010950	SEC-C motif; Region: SEC-C; pfam02810
866768010951	SecA regulator SecM; Provisional; Region: PRK02943
866768010952	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
866768010953	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
866768010954	cell division protein FtsZ; Validated; Region: PRK09330
866768010955	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
866768010956	nucleotide binding site [chemical binding]; other site
866768010957	SulA interaction site; other site
866768010958	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
866768010959	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
866768010960	Cell division protein FtsA; Region: FtsA; pfam14450
866768010961	cell division protein FtsQ; Provisional; Region: PRK10775
866768010962	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
866768010963	Cell division protein FtsQ; Region: FtsQ; pfam03799
866768010964	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
866768010965	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
866768010966	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
866768010967	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
866768010968	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
866768010969	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
866768010970	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
866768010971	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
866768010972	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
866768010973	active site
866768010974	homodimer interface [polypeptide binding]; other site
866768010975	cell division protein FtsW; Provisional; Region: PRK10774
866768010976	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
866768010977	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
866768010978	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
866768010979	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
866768010980	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
866768010981	Mg++ binding site [ion binding]; other site
866768010982	putative catalytic motif [active]
866768010983	putative substrate binding site [chemical binding]; other site
866768010984	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
866768010985	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
866768010986	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
866768010987	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
866768010988	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
866768010989	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
866768010990	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
866768010991	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
866768010992	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
866768010993	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
866768010994	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
866768010995	cell division protein FtsL; Provisional; Region: PRK10772
866768010996	16S rRNA (cytosine(1402)-N(4))-methyltransferase; Region: TIGR00006
866768010997	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
866768010998	mraZ protein; Region: TIGR00242
866768010999	MraZ protein; Region: MraZ; pfam02381
866768011000	MraZ protein; Region: MraZ; pfam02381
866768011001	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
866768011002	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
866768011003	DNA binding site [nucleotide binding]
866768011004	domain linker motif; other site
866768011005	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
866768011006	dimerization interface [polypeptide binding]; other site
866768011007	ligand binding site [chemical binding]; other site
866768011008	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
866768011009	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
866768011010	putative valine binding site [chemical binding]; other site
866768011011	dimer interface [polypeptide binding]; other site
866768011012	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
866768011013	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
866768011014	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
866768011015	PYR/PP interface [polypeptide binding]; other site
866768011016	dimer interface [polypeptide binding]; other site
866768011017	TPP binding site [chemical binding]; other site
866768011018	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
866768011019	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
866768011020	TPP-binding site [chemical binding]; other site
866768011021	dimer interface [polypeptide binding]; other site
866768011022	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
866768011023	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768011024	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
866768011025	putative substrate binding pocket [chemical binding]; other site
866768011026	putative dimerization interface [polypeptide binding]; other site
866768011027	leu operon leader peptide; Provisional; Region: PRK09925
866768011028	2-isopropylmalate synthase; Validated; Region: PRK00915
866768011029	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
866768011030	active site
866768011031	catalytic residues [active]
866768011032	metal binding site [ion binding]; metal-binding site
866768011033	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
866768011034	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
866768011035	tartrate dehydrogenase; Region: TTC; TIGR02089
866768011036	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
866768011037	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
866768011038	substrate binding site [chemical binding]; other site
866768011039	ligand binding site [chemical binding]; other site
866768011040	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
866768011041	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
866768011042	substrate binding site [chemical binding]; other site
866768011043	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768011044	sugar efflux transporter; Region: 2A0120; TIGR00899
866768011045	putative substrate translocation pore; other site
866768011046	transcriptional regulator SgrR; Provisional; Region: PRK13626
866768011047	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
866768011048	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
866768011049	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
866768011050	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
866768011051	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
866768011052	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768011053	dimer interface [polypeptide binding]; other site
866768011054	conserved gate region; other site
866768011055	putative PBP binding loops; other site
866768011056	ABC-ATPase subunit interface; other site
866768011057	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768011058	dimer interface [polypeptide binding]; other site
866768011059	conserved gate region; other site
866768011060	putative PBP binding loops; other site
866768011061	ABC-ATPase subunit interface; other site
866768011062	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
866768011063	ATP-binding cassette domain of the thiamine transport system; Region: ABC_ThiQ_thiamine_transporter; cd03298
866768011064	Walker A/P-loop; other site
866768011065	ATP binding site [chemical binding]; other site
866768011066	Q-loop/lid; other site
866768011067	ABC transporter signature motif; other site
866768011068	Walker B; other site
866768011069	D-loop; other site
866768011070	H-loop/switch region; other site
866768011071	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
866768011072	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
866768011073	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
866768011074	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
866768011075	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768011076	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768011077	ribulokinase; Provisional; Region: PRK04123
866768011078	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
866768011079	N- and C-terminal domain interface [polypeptide binding]; other site
866768011080	active site
866768011081	MgATP binding site [chemical binding]; other site
866768011082	catalytic site [active]
866768011083	metal binding site [ion binding]; metal-binding site
866768011084	carbohydrate binding site [chemical binding]; other site
866768011085	homodimer interface [polypeptide binding]; other site
866768011086	L-arabinose isomerase; Provisional; Region: PRK02929
866768011087	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
866768011088	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
866768011089	trimer interface [polypeptide binding]; other site
866768011090	putative substrate binding site [chemical binding]; other site
866768011091	putative metal binding site [ion binding]; other site
866768011092	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
866768011093	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
866768011094	intersubunit interface [polypeptide binding]; other site
866768011095	active site
866768011096	Zn2+ binding site [ion binding]; other site
866768011097	DNA polymerase II; Reviewed; Region: PRK05762
866768011098	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
866768011099	active site
866768011100	catalytic site [active]
866768011101	substrate binding site [chemical binding]; other site
866768011102	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
866768011103	active site
866768011104	metal-binding site
866768011105	ATP-dependent helicase HepA; Validated; Region: PRK04914
866768011106	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
866768011107	ATP binding site [chemical binding]; other site
866768011108	putative Mg++ binding site [ion binding]; other site
866768011109	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
866768011110	nucleotide binding region [chemical binding]; other site
866768011111	ATP-binding site [chemical binding]; other site
866768011112	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
866768011113	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
866768011114	active site
866768011115	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
866768011116	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
866768011117	putative metal binding site [ion binding]; other site
866768011118	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
866768011119	HSP70 interaction site [polypeptide binding]; other site
866768011120	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
866768011121	OstA-like protein; Region: OstA; pfam03968
866768011122	Organic solvent tolerance protein; Region: OstA_C; pfam04453
866768011123	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
866768011124	SurA N-terminal domain; Region: SurA_N; pfam09312
866768011125	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
866768011126	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
866768011127	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
866768011128	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
866768011129	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
866768011130	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
866768011131	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
866768011132	bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Region: apaH; TIGR00668
866768011133	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
866768011134	active site
866768011135	metal binding site [ion binding]; metal-binding site
866768011136	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
866768011137	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
866768011138	folate binding site [chemical binding]; other site
866768011139	NADP+ binding site [chemical binding]; other site
866768011140	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
866768011141	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
866768011142	TrkA-N domain; Region: TrkA_N; pfam02254
866768011143	glutathione-regulated potassium-efflux system ancillary protein KefF; Provisional; Region: PRK00871
866768011144	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768011145	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
866768011146	putative substrate translocation pore; other site
866768011147	ferredoxin-like protein FixX; Provisional; Region: PRK15449
866768011148	putative oxidoreductase FixC; Provisional; Region: PRK10157
866768011149	putative electron transfer flavoprotein FixB; Provisional; Region: fixB; PRK03363
866768011150	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF; cd01985
866768011151	Ligand binding site [chemical binding]; other site
866768011152	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
866768011153	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
866768011154	Ligand binding site [chemical binding]; other site
866768011155	Electron transfer flavoprotein domain; Region: ETF; pfam01012
866768011156	L-carnitine/gamma-butyrobetaine antiporter; Provisional; Region: PRK03356
866768011157	crotonobetainyl-CoA dehydrogenase; Validated; Region: PRK03354
866768011158	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
866768011159	active site
866768011160	putative crotonobetaine/carnitine-CoA ligase; Validated; Region: caiC; PRK08008
866768011161	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_DitJ_like; cd05934
866768011162	acyl-activating enzyme (AAE) consensus motif; other site
866768011163	putative AMP binding site [chemical binding]; other site
866768011164	putative active site [active]
866768011165	putative CoA binding site [chemical binding]; other site
866768011166	carnitinyl-CoA dehydratase; Provisional; Region: PRK03580
866768011167	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
866768011168	substrate binding site [chemical binding]; other site
866768011169	oxyanion hole (OAH) forming residues; other site
866768011170	trimer interface [polypeptide binding]; other site
866768011171	carnitine operon protein CaiE; Provisional; Region: PRK13627
866768011172	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
866768011173	putative trimer interface [polypeptide binding]; other site
866768011174	putative metal binding site [ion binding]; other site
866768011175	DNA-binding transcriptional activator CaiF; Provisional; Region: PRK11476
866768011176	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
866768011177	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
866768011178	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
866768011179	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
866768011180	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
866768011181	ATP-grasp domain; Region: ATP-grasp_4; cl17255
866768011182	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
866768011183	IMP binding site; other site
866768011184	dimer interface [polypeptide binding]; other site
866768011185	interdomain contacts; other site
866768011186	partial ornithine binding site; other site
866768011187	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
866768011188	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
866768011189	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
866768011190	catalytic site [active]
866768011191	subunit interface [polypeptide binding]; other site
866768011192	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
866768011193	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
866768011194	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
866768011195	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
866768011196	active site
866768011197	tetramer interface [polypeptide binding]; other site
866768011198	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
866768011199	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
866768011200	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
866768011201	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
866768011202	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
866768011203	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
866768011204	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
866768011205	HIGH motif; other site
866768011206	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
866768011207	active site
866768011208	KMSKS motif; other site
866768011209	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
866768011210	tRNA binding surface [nucleotide binding]; other site
866768011211	anticodon binding site; other site
866768011212	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
866768011213	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
866768011214	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
866768011215	active site
866768011216	Riboflavin kinase; Region: Flavokinase; smart00904
866768011217	Protein of unknown function (DUF2575); Region: DUF2575; pfam10837
866768011218	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
866768011219	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
866768011220	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
866768011221	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
866768011222	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
866768011223	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
866768011224	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768011225	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
866768011226	putative dimerization interface [polypeptide binding]; other site
866768011227	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
866768011228	Hok/gef family; Region: HOK_GEF; pfam01848
866768011229	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
866768011230	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
866768011231	chaperone protein DnaJ; Provisional; Region: PRK10767
866768011232	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
866768011233	HSP70 interaction site [polypeptide binding]; other site
866768011234	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
866768011235	substrate binding site [polypeptide binding]; other site
866768011236	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
866768011237	Zn binding sites [ion binding]; other site
866768011238	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
866768011239	dimer interface [polypeptide binding]; other site
866768011240	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
866768011241	Nucleotide-binding domain of human HSPA9, Escherichia coli DnaK, and similar proteins; Region: HSPA9-like_NBD; cd11733
866768011242	nucleotide binding site [chemical binding]; other site
866768011243	NEF interaction site [polypeptide binding]; other site
866768011244	SBD interface [polypeptide binding]; other site
866768011245	hypothetical protein; Provisional; Region: PRK10154
866768011246	hypothetical protein; Provisional; Region: PRK10236
866768011247	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
866768011248	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
866768011249	hypothetical protein; Provisional; Region: PRK10659
866768011250	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
866768011251	MPT binding site; other site
866768011252	trimer interface [polypeptide binding]; other site
866768011253	transaldolase-like protein; Provisional; Region: PTZ00411
866768011254	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
866768011255	active site
866768011256	dimer interface [polypeptide binding]; other site
866768011257	catalytic residue [active]
866768011258	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
866768011259	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
866768011260	hypothetical protein; Validated; Region: PRK02101
866768011261	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
866768011262	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
866768011263	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
866768011264	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768011265	catalytic residue [active]
866768011266	homoserine kinase; Region: thrB; TIGR00191
866768011267	Protein of unknown function; Region: YhfT; pfam10797
866768011268	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
866768011269	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
866768011270	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
866768011271	putative catalytic residues [active]
866768011272	putative nucleotide binding site [chemical binding]; other site
866768011273	putative aspartate binding site [chemical binding]; other site
866768011274	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
866768011275	dimer interface [polypeptide binding]; other site
866768011276	putative threonine allosteric regulatory site; other site
866768011277	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
866768011278	putative threonine allosteric regulatory site; other site
866768011279	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
866768011280	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
866768011281	putative RNA methyltransferase; Provisional; Region: PRK10433
866768011282	RNA methyltransferase, TrmH family, group 1; Region: rRNA_methyl_1; TIGR00050
866768011283	two-component response regulator; Provisional; Region: PRK11173
866768011284	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768011285	active site
866768011286	phosphorylation site [posttranslational modification]
866768011287	intermolecular recognition site; other site
866768011288	dimerization interface [polypeptide binding]; other site
866768011289	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
866768011290	DNA binding site [nucleotide binding]
866768011291	Inner membrane protein involved in colicin E2 resistance [Defense mechanisms]; Region: CreD; COG4452
866768011292	sensory histidine kinase CreC; Provisional; Region: PRK11100
866768011293	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
866768011294	dimerization interface [polypeptide binding]; other site
866768011295	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
866768011296	dimer interface [polypeptide binding]; other site
866768011297	phosphorylation site [posttranslational modification]
866768011298	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866768011299	ATP binding site [chemical binding]; other site
866768011300	Mg2+ binding site [ion binding]; other site
866768011301	G-X-G motif; other site
866768011302	DNA-binding response regulator CreB; Provisional; Region: PRK11083
866768011303	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768011304	active site
866768011305	phosphorylation site [posttranslational modification]
866768011306	intermolecular recognition site; other site
866768011307	dimerization interface [polypeptide binding]; other site
866768011308	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
866768011309	DNA binding site [nucleotide binding]
866768011310	hypothetical protein; Provisional; Region: PRK10756
866768011311	CreA protein; Region: CreA; pfam05981
866768011312	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
866768011313	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768011314	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
866768011315	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
866768011316	catalytic core [active]
866768011317	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
866768011318	Trp operon repressor; Provisional; Region: PRK01381
866768011319	lytic murein transglycosylase; Provisional; Region: PRK11619
866768011320	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
866768011321	N-acetyl-D-glucosamine binding site [chemical binding]; other site
866768011322	catalytic residue [active]
866768011323	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
866768011324	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866768011325	Walker A/P-loop; other site
866768011326	ATP binding site [chemical binding]; other site
866768011327	Q-loop/lid; other site
866768011328	ABC transporter signature motif; other site
866768011329	Walker B; other site
866768011330	D-loop; other site
866768011331	H-loop/switch region; other site
866768011332	ABC transporter; Region: ABC_tran_2; pfam12848
866768011333	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
866768011334	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
866768011335	non-specific DNA binding site [nucleotide binding]; other site
866768011336	salt bridge; other site
866768011337	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
866768011338	sequence-specific DNA binding site [nucleotide binding]; other site
866768011339	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
866768011340	active site
866768011341	(T/H)XGH motif; other site
866768011342	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
866768011343	DNA repair protein RadA; Region: sms; TIGR00416
866768011344	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
866768011345	Walker A motif/ATP binding site; other site
866768011346	ATP binding site [chemical binding]; other site
866768011347	Walker B motif; other site
866768011348	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
866768011349	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
866768011350	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866768011351	motif II; other site
866768011352	hypothetical protein; Provisional; Region: PRK11246
866768011353	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
866768011354	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
866768011355	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
866768011356	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
866768011357	non-specific DNA binding site [nucleotide binding]; other site
866768011358	salt bridge; other site
866768011359	sequence-specific DNA binding site [nucleotide binding]; other site
866768011360	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
866768011361	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
866768011362	phosphopentomutase; Provisional; Region: PRK05362
866768011363	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
866768011364	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
866768011365	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
866768011366	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
866768011367	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
866768011368	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
866768011369	intersubunit interface [polypeptide binding]; other site
866768011370	active site
866768011371	catalytic residue [active]
866768011372	hypothetical protein; Provisional; Region: PRK10977
866768011373	glycine radical enzyme activase, YjjW family; Region: activase_YjjW; TIGR04041
866768011374	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866768011375	FeS/SAM binding site; other site
866768011376	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
866768011377	active site
866768011378	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
866768011379	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
866768011380	active site
866768011381	nucleophile elbow; other site
866768011382	periplasmic protein; Provisional; Region: PRK10568
866768011383	BON domain; Region: BON; pfam04972
866768011384	BON domain; Region: BON; pfam04972
866768011385	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
866768011386	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
866768011387	G1 box; other site
866768011388	putative GEF interaction site [polypeptide binding]; other site
866768011389	GTP/Mg2+ binding site [chemical binding]; other site
866768011390	Switch I region; other site
866768011391	G2 box; other site
866768011392	G3 box; other site
866768011393	Switch II region; other site
866768011394	G4 box; other site
866768011395	G5 box; other site
866768011396	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
866768011397	dUMP phosphatase; Provisional; Region: PRK09449
866768011398	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866768011399	motif II; other site
866768011400	ribosomal-protein-alanine N-acetyltransferase; Provisional; Region: rimI; PRK09491
866768011401	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
866768011402	Coenzyme A binding pocket [chemical binding]; other site
866768011403	DNA polymerase III subunit psi; Validated; Region: PRK06856
866768011404	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
866768011405	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
866768011406	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768011407	S-adenosylmethionine binding site [chemical binding]; other site
866768011408	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
866768011409	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
866768011410	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
866768011411	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
866768011412	DNA-binding transcriptional activator BglJ; Provisional; Region: PRK11475
866768011413	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
866768011414	DNA binding residues [nucleotide binding]
866768011415	dimerization interface [polypeptide binding]; other site
866768011416	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
866768011417	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
866768011418	DNA binding residues [nucleotide binding]
866768011419	dimerization interface [polypeptide binding]; other site
866768011420	Uncharacterized conserved protein [Function unknown]; Region: COG2966
866768011421	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
866768011422	hypothetical protein; Provisional; Region: PRK09917
866768011423	primosomal protein DnaI; Provisional; Region: PRK02854
866768011424	DNA replication protein DnaC; Validated; Region: PRK07952
866768011425	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866768011426	Walker A motif; other site
866768011427	ATP binding site [chemical binding]; other site
866768011428	Walker B motif; other site
866768011429	hypothetical protein; Provisional; Region: PRK11667
866768011430	phosphoglycerol transferase I; Provisional; Region: PRK03776
866768011431	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
866768011432	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
866768011433	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
866768011434	putative NAD(P) binding site [chemical binding]; other site
866768011435	catalytic Zn binding site [ion binding]; other site
866768011436	structural Zn binding site [ion binding]; other site
866768011437	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768011438	D-galactonate transporter; Region: 2A0114; TIGR00893
866768011439	putative substrate translocation pore; other site
866768011440	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
866768011441	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
866768011442	dimer interface [polypeptide binding]; other site
866768011443	ligand binding site [chemical binding]; other site
866768011444	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
866768011445	dimerization interface [polypeptide binding]; other site
866768011446	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
866768011447	dimer interface [polypeptide binding]; other site
866768011448	putative CheW interface [polypeptide binding]; other site
866768011449	homoprotocatechuate degradation operon regulator, HpaR; Region: HpaR; TIGR02337
866768011450	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
866768011451	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase; Provisional; Region: PRK15203
866768011452	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit; Region: HpaG-N-term; TIGR02305
866768011453	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
866768011454	5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Region: HpaE; TIGR02299
866768011455	Human aldehyde dehydrogenase family 8 member A1-like; Region: ALDH_F8_HMSADH; cd07093
866768011456	NAD binding site [chemical binding]; other site
866768011457	catalytic residues [active]
866768011458	The Class III extradiol dioxygenase, homoprotocatechuate 2,3-dioxygenase, catalyzes the key ring cleavage step in the metabolism of homoprotocatechuate; Region: HPCD; cd07370
866768011459	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
866768011460	putative active site [active]
866768011461	putative metal binding site [ion binding]; other site
866768011462	5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cd00580
866768011463	putative substrate binding pocket [chemical binding]; other site
866768011464	trimer interface [polypeptide binding]; other site
866768011465	2-oxo-hepta-3-ene-1,7-dioic acid hydratase; Region: HpaH; TIGR02312
866768011466	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
866768011467	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768011468	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
866768011469	putative substrate translocation pore; other site
866768011470	4-hydroxyphenylacetate catabolism regulatory protein HpaA; Region: HpaA; TIGR02297
866768011471	Cupin domain; Region: Cupin_2; pfam07883
866768011472	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768011473	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Region: HpaB-2; TIGR02310
866768011474	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
866768011475	4-hydroxyphenylacetate 3-monooxygenase reductase subunit; Provisional; Region: hpaC; PRK15486
866768011476	carbon starvation protein A; Provisional; Region: PRK15015
866768011477	Carbon starvation protein CstA; Region: CstA; pfam02554
866768011478	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
866768011479	Uncharacterized small protein [Function unknown]; Region: COG2879
866768011480	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
866768011481	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
866768011482	P-loop, Walker A motif; other site
866768011483	Base recognition motif; other site
866768011484	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
866768011485	Restriction endonuclease [Defense mechanisms]; Region: Mrr; COG1715
866768011486	Mrr N-terminal domain; Region: Mrr_N; pfam14338
866768011487	Restriction endonuclease; Region: Mrr_cat; pfam04471
866768011488	type I restriction enzyme EcoKI subunit R; Provisional; Region: hsdR; PRK11448
866768011489	Domain of unknown function (DUF4145); Region: DUF4145; pfam13643
866768011490	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; cl14958
866768011491	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
866768011492	ATP binding site [chemical binding]; other site
866768011493	putative Mg++ binding site [ion binding]; other site
866768011494	HsdM N-terminal domain; Region: HsdM_N; pfam12161
866768011495	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
866768011496	Methyltransferase domain; Region: Methyltransf_26; pfam13659
866768011497	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
866768011498	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
866768011499	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
866768011500	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
866768011501	endoribonuclease SymE; Provisional; Region: PRK13605
866768011502	5-methylcytosine-specific restriction enzyme subunit McrB; Provisional; Region: PRK11331
866768011503	Domain of unknown function (DUF3578); Region: DUF3578; pfam12102
866768011504	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866768011505	Walker A motif; other site
866768011506	ATP binding site [chemical binding]; other site
866768011507	Walker B motif; other site
866768011508	arginine finger; other site
866768011509	5-methylcytosine-specific restriction enzyme subunit McrC; Provisional; Region: PRK09736
866768011510	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
866768011511	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
866768011512	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
866768011513	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
866768011514	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
866768011515	multidrug efflux system protein MdtM; Provisional; Region: PRK15403
866768011516	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768011517	putative substrate translocation pore; other site
866768011518	Predicted membrane protein [Function unknown]; Region: COG2733
866768011519	Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB [Amino acid transport and metabolism]; Region: HgdB; COG1775
866768011520	benzoyl-CoA reductase, subunit C; Region: benz_CoA_red_C; TIGR02263
866768011521	Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism]; Region: COG1924
866768011522	CoA-substrate-specific enzyme activase, putative; Region: CoA_E_activ; TIGR00241
866768011523	Protein of unknown function (DUF3343); Region: DUF3343; pfam11823
866768011524	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3204
866768011525	SdiA-regulated; Region: SdiA-regulated; cd09971
866768011526	putative active site [active]
866768011527	Protein of unknown function (DUF1228); Region: DUF1228; pfam06779
866768011528	RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; Region: KptA; COG1859
866768011529	RNA 2'-phosphotransferase; Reviewed; Region: PRK00819
866768011530	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
866768011531	Nucleoside recognition; Region: Gate; pfam07670
866768011532	hypothetical protein; Provisional; Region: PRK10519
866768011533	Isoaspartyl dipeptidase hydrolyzes the beta-L-isoaspartyl linkages in dipeptides, as part of the degradative pathway to eliminate proteins with beta-L-isoaspartyl peptide bonds, bonds whereby the beta-group of an aspartate forms the peptide link with the...; Region: Isoaspartyl-dipeptidase; cd01308
866768011534	isoaspartyl dipeptidase IadA; Region: isoAsp_dipep; TIGR01975
866768011535	dimer interface [polypeptide binding]; other site
866768011536	active site
866768011537	cell density-dependent motility repressor; Provisional; Region: PRK10082
866768011538	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768011539	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
866768011540	DNA replication/recombination/repair protein; Provisional; Region: iraD; PRK14128
866768011541	Protein of unknown function (DUF2686); Region: DUF2686; pfam10887
866768011542	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
866768011543	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
866768011544	DNA-binding site [nucleotide binding]; DNA binding site
866768011545	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
866768011546	D-mannonate oxidoreductase; Provisional; Region: PRK15037
866768011547	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
866768011548	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
866768011549	mannonate dehydratase; Region: uxuA; TIGR00695
866768011550	mannonate dehydratase; Provisional; Region: PRK03906
866768011551	fructuronate transporter; Provisional; Region: PRK10034
866768011552	gluconate transporter; Region: gntP; TIGR00791
866768011553	Mannose binding  domain of FimH and related proteins; Region: FimH_man-bind; cd10466
866768011554	mannosyl binding site [chemical binding]; other site
866768011555	Fimbrial protein; Region: Fimbrial; pfam00419
866768011556	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
866768011557	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
866768011558	outer membrane usher protein; Provisional; Region: PRK15193
866768011559	PapC N-terminal domain; Region: PapC_N; pfam13954
866768011560	Type VII secretion system (T7SS), usher protein; Region: Usher; pfam00577
866768011561	PapC C-terminal domain; Region: PapC_C; pfam13953
866768011562	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
866768011563	Gram-negative pili assembly chaperone, N-terminal domain; Region: Pili_assembly_N; pfam00345
866768011564	Gram-negative pili assembly chaperone, C-terminal domain; Region: Pili_assembly_C; pfam02753
866768011565	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
866768011566	Fimbrial protein; Region: Fimbrial; cl01416
866768011567	FimB and FimE and related proteins, DNA breaking-rejoining enzymes, integrase/recombinases, catalytic domain. This CD includes those proteins similar to E.coli FimE and FimB regulatory proteins and Proteus mirabilis MrpI; Region: INT_FimBE_C; cd01197
866768011568	Int/Topo IB signature motif; other site
866768011569	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
866768011570	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
866768011571	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
866768011572	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
866768011573	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
866768011574	active site
866768011575	Int/Topo IB signature motif; other site
866768011576	DNA binding site [nucleotide binding]
866768011577	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; cl11629
866768011578	N-acetylneuraminic acid mutarotase; Provisional; Region: PRK14131
866768011579	Kelch motif; Region: Kelch_1; pfam01344
866768011580	Domain of unknown function (DUF303); Region: DUF303; pfam03629
866768011581	hypothetical protein; Provisional; Region: PRK13687
866768011582	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
866768011583	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
866768011584	Coenzyme A binding pocket [chemical binding]; other site
866768011585	Methyltransferase domain; Region: Methyltransf_31; pfam13847
866768011586	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768011587	S-adenosylmethionine binding site [chemical binding]; other site
866768011588	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
866768011589	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
866768011590	oligomer interface [polypeptide binding]; other site
866768011591	active site
866768011592	metal binding site [ion binding]; metal-binding site
866768011593	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
866768011594	active site
866768011595	P-loop; other site
866768011596	phosphorylation site [posttranslational modification]
866768011597	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
866768011598	PTS system, galactitol-specific IIC component; Region: EIIC-GAT; TIGR00827
866768011599	membrane complex biogenesis protein, BtpA family; Region: thylakoid_BtpA; TIGR00259
866768011600	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
866768011601	active site
866768011602	phosphorylation site [posttranslational modification]
866768011603	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
866768011604	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
866768011605	substrate binding site [chemical binding]; other site
866768011606	hexamer interface [polypeptide binding]; other site
866768011607	metal binding site [ion binding]; metal-binding site
866768011608	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
866768011609	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
866768011610	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
866768011611	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
866768011612	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
866768011613	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
866768011614	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
866768011615	RNA polymerase sigma factor FecI; Provisional; Region: PRK09651
866768011616	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
866768011617	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
866768011618	DNA binding residues [nucleotide binding]
866768011619	fec operon regulator FecR; Reviewed; Region: PRK09774
866768011620	FecR protein; Region: FecR; pfam04773
866768011621	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
866768011622	Secretin and TonB N terminus short domain; Region: STN; smart00965
866768011623	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
866768011624	N-terminal plug; other site
866768011625	ligand-binding site [chemical binding]; other site
866768011626	iron-dicitrate transporter substrate-binding subunit; Provisional; Region: fecB; PRK11411
866768011627	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
866768011628	siderophore binding site; other site
866768011629	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
866768011630	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
866768011631	dimer interface [polypeptide binding]; other site
866768011632	ABC-ATPase subunit  interface; other site
866768011633	putative PBP binding regions; other site
866768011634	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
866768011635	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
866768011636	ABC-ATPase subunit  interface; other site
866768011637	dimer interface [polypeptide binding]; other site
866768011638	putative PBP binding regions; other site
866768011639	iron-dicitrate transporter ATP-binding subunit; Provisional; Region: fecE; PRK11231
866768011640	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
866768011641	Walker A/P-loop; other site
866768011642	ATP binding site [chemical binding]; other site
866768011643	Q-loop/lid; other site
866768011644	ABC transporter signature motif; other site
866768011645	Walker B; other site
866768011646	D-loop; other site
866768011647	H-loop/switch region; other site
866768011648	Predicted dinucleotide-binding enzymes [General function prediction only]; Region: COG2085
866768011649	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
866768011650	Transposase; Region: HTH_Tnp_1; pfam01527
866768011651	putative transposase OrfB; Reviewed; Region: PHA02517
866768011652	Integrase core domain; Region: rve; pfam00665
866768011653	Integrase core domain; Region: rve_3; pfam13683
866768011654	BCCT family transporter; Region: BCCT; cl00569
866768011655	Predicted membrane protein [Function unknown]; Region: COG4325
866768011656	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
866768011657	Transposase; Region: HTH_Tnp_1; cl17663
866768011658	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
866768011659	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
866768011660	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
866768011661	putative sialic acid transporter; Provisional; Region: PRK12307
866768011662	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768011663	putative substrate translocation pore; other site
866768011664	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
866768011665	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
866768011666	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
866768011667	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
866768011668	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
866768011669	active site
866768011670	Int/Topo IB signature motif; other site
866768011671	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
866768011672	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
866768011673	putative NAD(P) binding site [chemical binding]; other site
866768011674	putative substrate binding site [chemical binding]; other site
866768011675	catalytic Zn binding site [ion binding]; other site
866768011676	structural Zn binding site [ion binding]; other site
866768011677	dimer interface [polypeptide binding]; other site
866768011678	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
866768011679	ATP-binding site [chemical binding]; other site
866768011680	Gluconate-6-phosphate binding site [chemical binding]; other site
866768011681	Shikimate kinase; Region: SKI; pfam01202
866768011682	L-idonate 5-dehydrogenase; Provisional; Region: PRK09880
866768011683	L-idonate 5-dehydrogenase; Region: idonate-5-DH; cd08232
866768011684	putative NAD(P) binding site [chemical binding]; other site
866768011685	catalytic Zn binding site [ion binding]; other site
866768011686	gluconate 5-dehydrogenase; Provisional; Region: PRK08085
866768011687	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
866768011688	NADP binding site [chemical binding]; other site
866768011689	homodimer interface [polypeptide binding]; other site
866768011690	active site
866768011691	fructuronate transporter; Provisional; Region: PRK10034; cl15264
866768011692	gluconate transporter; Region: gntP; TIGR00791
866768011693	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
866768011694	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
866768011695	DNA binding site [nucleotide binding]
866768011696	domain linker motif; other site
866768011697	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
866768011698	putative dimerization interface [polypeptide binding]; other site
866768011699	putative ligand binding site [chemical binding]; other site
866768011700	Bacterial protein of unknown function (DUF853); Region: DUF853; pfam05872
866768011701	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
866768011702	Walker A motif; other site
866768011703	ATP binding site [chemical binding]; other site
866768011704	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
866768011705	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
866768011706	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
866768011707	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
866768011708	multifunctional aminopeptidase A; Provisional; Region: PRK00913
866768011709	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
866768011710	interface (dimer of trimers) [polypeptide binding]; other site
866768011711	Substrate-binding/catalytic site; other site
866768011712	Zn-binding sites [ion binding]; other site
866768011713	DNA polymerase III subunit chi; Validated; Region: PRK05728
866768011714	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
866768011715	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
866768011716	HIGH motif; other site
866768011717	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
866768011718	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
866768011719	active site
866768011720	KMSKS motif; other site
866768011721	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
866768011722	tRNA binding surface [nucleotide binding]; other site
866768011723	anticodon binding site; other site
866768011724	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
866768011725	Predicted membrane protein [Function unknown]; Region: COG4269
866768011726	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3076
866768011727	RNase E inhibitor protein; Provisional; Region: PRK11191
866768011728	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
866768011729	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
866768011730	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
866768011731	Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism]; Region: EbgC; COG2731
866768011732	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
866768011733	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
866768011734	oxidoreductase; Provisional; Region: PRK12742
866768011735	classical (c) SDRs; Region: SDR_c; cd05233
866768011736	NAD(P) binding site [chemical binding]; other site
866768011737	active site
866768011738	YjgH belongs to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgH_like; cd02198
866768011739	homotrimer interaction site [polypeptide binding]; other site
866768011740	putative active site [active]
866768011741	aspartate carbamoyltransferase; Region: asp_carb_tr; TIGR00670
866768011742	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
866768011743	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
866768011744	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
866768011745	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
866768011746	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
866768011747	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
866768011748	homotrimer interaction site [polypeptide binding]; other site
866768011749	putative active site [active]
866768011750	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
866768011751	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
866768011752	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
866768011753	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
866768011754	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866768011755	motif II; other site
866768011756	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
866768011757	trehalose repressor; Provisional; Region: treR; PRK09492
866768011758	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
866768011759	DNA binding site [nucleotide binding]
866768011760	domain linker motif; other site
866768011761	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
866768011762	dimerization interface [polypeptide binding]; other site
866768011763	ligand binding site [chemical binding]; other site
866768011764	PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional; Region: PRK11007
866768011765	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
866768011766	active site turn [active]
866768011767	phosphorylation site [posttranslational modification]
866768011768	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
866768011769	trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933
866768011770	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
866768011771	Ca binding site [ion binding]; other site
866768011772	active site
866768011773	catalytic site [active]
866768011774	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
866768011775	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
866768011776	ATP cone domain; Region: ATP-cone; pfam03477
866768011777	Class III ribonucleotide reductase; Region: RNR_III; cd01675
866768011778	effector binding site; other site
866768011779	active site
866768011780	Zn binding site [ion binding]; other site
866768011781	glycine loop; other site
866768011782	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
866768011783	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866768011784	FeS/SAM binding site; other site
866768011785	cytochrome b562; Provisional; Region: PRK15058
866768011786	peptidase PmbA; Provisional; Region: PRK11040
866768011787	hypothetical protein; Provisional; Region: PRK05255
866768011788	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
866768011789	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
866768011790	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
866768011791	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
866768011792	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
866768011793	AMP binding site [chemical binding]; other site
866768011794	metal binding site [ion binding]; metal-binding site
866768011795	active site
866768011796	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
866768011797	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
866768011798	TM-ABC transporter signature motif; other site
866768011799	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
866768011800	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
866768011801	TM-ABC transporter signature motif; other site
866768011802	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
866768011803	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
866768011804	Walker A/P-loop; other site
866768011805	ATP binding site [chemical binding]; other site
866768011806	Q-loop/lid; other site
866768011807	ABC transporter signature motif; other site
866768011808	Walker B; other site
866768011809	D-loop; other site
866768011810	H-loop/switch region; other site
866768011811	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
866768011812	Periplasmic binding domain of ABC-type YtfQ-like transport systems; Region: PBP1_YtfQ_like; cd06309
866768011813	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
866768011814	putative ligand binding site [chemical binding]; other site
866768011815	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
866768011816	dimer interface [polypeptide binding]; other site
866768011817	substrate binding site [chemical binding]; other site
866768011818	metal binding sites [ion binding]; metal-binding site
866768011819	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
866768011820	putative active site pocket [active]
866768011821	dimerization interface [polypeptide binding]; other site
866768011822	putative catalytic residue [active]
866768011823	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
866768011824	Family of unknown function (DUF490); Region: DUF490; pfam04357
866768011825	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
866768011826	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
866768011827	Surface antigen; Region: Bac_surface_Ag; pfam01103
866768011828	methionine sulfoxide reductase A; Provisional; Region: PRK00058
866768011829	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
866768011830	Domain of unknown function DUF21; Region: DUF21; pfam01595
866768011831	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
866768011832	Transporter associated domain; Region: CorC_HlyC; smart01091
866768011833	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
866768011834	Predicted transcriptional regulator [General function prediction only]; Region: COG3054
866768011835	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
866768011836	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
866768011837	active site
866768011838	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
866768011839	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
866768011840	active site
866768011841	metal binding site [ion binding]; metal-binding site
866768011842	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
866768011843	Predicted transcriptional regulators [Transcription]; Region: COG1733
866768011844	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
866768011845	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
866768011846	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
866768011847	NADP binding site [chemical binding]; other site
866768011848	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
866768011849	EamA-like transporter family; Region: EamA; pfam00892
866768011850	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
866768011851	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
866768011852	Hemerythrin-like domain; Region: Hr-like; cd12108
866768011853	Fe binding site [ion binding]; other site
866768011854	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
866768011855	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
866768011856	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
866768011857	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
866768011858	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
866768011859	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
866768011860	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
866768011861	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
866768011862	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
866768011863	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: PRK12745
866768011864	putative beta-ketoacyl acyl carrier protein [ACP] reductase (BKR), subgroup 1, classical (c) SDR; Region: BKR_1_SDR_c; cd05337
866768011865	putative NAD(P) binding site [chemical binding]; other site
866768011866	active site
866768011867	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
866768011868	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
866768011869	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
866768011870	substrate binding site [chemical binding]; other site
866768011871	oxyanion hole (OAH) forming residues; other site
866768011872	trimer interface [polypeptide binding]; other site
866768011873	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
866768011874	Coenzyme A transferase; Region: CoA_trans; smart00882
866768011875	Coenzyme A transferase; Region: CoA_trans; cl17247
866768011876	Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]; Region: SdhA; COG1053
866768011877	L-aspartate oxidase; Provisional; Region: PRK06175
866768011878	L-aspartate oxidase; Provisional; Region: PRK06175
866768011879	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768011880	D-galactonate transporter; Region: 2A0114; TIGR00893
866768011881	putative substrate translocation pore; other site
866768011882	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
866768011883	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
866768011884	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
866768011885	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
866768011886	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
866768011887	dimer interface [polypeptide binding]; other site
866768011888	ssDNA binding site [nucleotide binding]; other site
866768011889	tetramer (dimer of dimers) interface [polypeptide binding]; other site
866768011890	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
866768011891	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
866768011892	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
866768011893	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
866768011894	intersubunit interface [polypeptide binding]; other site
866768011895	active site
866768011896	Zn2+ binding site [ion binding]; other site
866768011897	L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13209
866768011898	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
866768011899	AP (apurinic/apyrimidinic) site pocket; other site
866768011900	DNA interaction; other site
866768011901	Metal-binding active site; metal-binding site
866768011902	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
866768011903	active site
866768011904	dimer interface [polypeptide binding]; other site
866768011905	magnesium binding site [ion binding]; other site
866768011906	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
866768011907	active site
866768011908	phosphorylation site [posttranslational modification]
866768011909	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
866768011910	active site
866768011911	P-loop; other site
866768011912	phosphorylation site [posttranslational modification]
866768011913	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
866768011914	PTS system ascorbate-specific transporter subunits IICB; Provisional; Region: PRK09548
866768011915	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
866768011916	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
866768011917	transcriptional repressor UlaR; Provisional; Region: PRK13509
866768011918	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
866768011919	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
866768011920	esterase; Provisional; Region: PRK10566
866768011921	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
866768011922	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
866768011923	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
866768011924	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
866768011925	Proteins involved in DNA damage response, similar to the AidB gene product; Region: AidB; cd01154
866768011926	FAD binding site [chemical binding]; other site
866768011927	substrate binding site [chemical binding]; other site
866768011928	catalytic residues [active]
866768011929	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
866768011930	Predicted integral membrane protein [Function unknown]; Region: COG5463
866768011931	Predicted membrane protein [Function unknown]; Region: COG3766
866768011932	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
866768011933	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
866768011934	Protein of unknown function (DUF2491); Region: DUF2491; pfam10679
866768011935	PspA/IM30 family; Region: PspA_IM30; pfam04012
866768011936	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3789
866768011937	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
866768011938	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
866768011939	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
866768011940	exoribonuclease R; Provisional; Region: PRK11642
866768011941	Ribonuclease R winged-helix domain; Region: HTH_12; pfam08461
866768011942	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
866768011943	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
866768011944	RNB domain; Region: RNB; pfam00773
866768011945	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
866768011946	RNA binding site [nucleotide binding]; other site
866768011947	Predicted transcriptional regulator [Transcription]; Region: COG1959
866768011948	transcriptional repressor NsrR; Provisional; Region: PRK11014
866768011949	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
866768011950	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
866768011951	GDP-binding site [chemical binding]; other site
866768011952	ACT binding site; other site
866768011953	IMP binding site; other site
866768011954	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3242
866768011955	FtsH protease regulator HflC; Provisional; Region: PRK11029
866768011956	Band_7_HflC: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfC (High frequency of lysogenization C). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflC; cd03405
866768011957	FtsH protease regulator HflK; Provisional; Region: PRK10930
866768011958	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
866768011959	Band_7_HflK: The band 7 domain of flotillin (reggie) like proteins. This group includes proteins similar to prokaryotic HlfK (High frequency of lysogenization K). Although many members of the band 7 family are lipid raft associated, prokaryote plasma...; Region: Band_7_HflK; cd03404
866768011960	GTPase HflX; Provisional; Region: PRK11058
866768011961	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
866768011962	HflX GTPase family; Region: HflX; cd01878
866768011963	G1 box; other site
866768011964	GTP/Mg2+ binding site [chemical binding]; other site
866768011965	Switch I region; other site
866768011966	G2 box; other site
866768011967	G3 box; other site
866768011968	Switch II region; other site
866768011969	G4 box; other site
866768011970	G5 box; other site
866768011971	bacterial Hfq-like; Region: Hfq; cd01716
866768011972	hexamer interface [polypeptide binding]; other site
866768011973	Sm1 motif; other site
866768011974	RNA binding site [nucleotide binding]; other site
866768011975	Sm2 motif; other site
866768011976	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
866768011977	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
866768011978	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
866768011979	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866768011980	ATP binding site [chemical binding]; other site
866768011981	Mg2+ binding site [ion binding]; other site
866768011982	G-X-G motif; other site
866768011983	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
866768011984	ATP binding site [chemical binding]; other site
866768011985	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
866768011986	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
866768011987	AMIN domain; Region: AMIN; pfam11741
866768011988	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
866768011989	active site
866768011990	metal binding site [ion binding]; metal-binding site
866768011991	ADP-binding protein; Provisional; Region: PRK10646
866768011992	putative carbohydrate kinase; Provisional; Region: PRK10565
866768011993	yjeF N-terminal region; Region: yjeF_nterm; TIGR00197
866768011994	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
866768011995	putative substrate binding site [chemical binding]; other site
866768011996	putative ATP binding site [chemical binding]; other site
866768011997	epoxyqueuosine reductase; Region: TIGR00276
866768011998	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
866768011999	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
866768012000	catalytic site [active]
866768012001	putative active site [active]
866768012002	putative substrate binding site [chemical binding]; other site
866768012003	dimer interface [polypeptide binding]; other site
866768012004	GTPase RsgA; Reviewed; Region: PRK12288
866768012005	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
866768012006	RNA binding site [nucleotide binding]; other site
866768012007	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
866768012008	GTPase/Zn-binding domain interface [polypeptide binding]; other site
866768012009	GTP/Mg2+ binding site [chemical binding]; other site
866768012010	G4 box; other site
866768012011	G5 box; other site
866768012012	G1 box; other site
866768012013	Switch I region; other site
866768012014	G2 box; other site
866768012015	G3 box; other site
866768012016	Switch II region; other site
866768012017	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
866768012018	putative mechanosensitive channel protein; Provisional; Region: PRK10929
866768012019	linker histone 1 and histone 5 domains; the basic subunit of chromatin is the nucleosome, consisting of an octamer of core histones, two full turns of DNA, a linker histone (H1 or H5) and a variable length of linker DNA; H1/H5 are chromatin-associated...; Region: H15; cl00073
866768012020	DNA-binding site [nucleotide binding]; DNA binding site
866768012021	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
866768012022	Mechanosensitive ion channel; Region: MS_channel; pfam00924
866768012023	inner membrane transporter YjeM; Provisional; Region: PRK15238
866768012024	poxB regulator PoxA; Provisional; Region: PRK09350
866768012025	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
866768012026	motif 1; other site
866768012027	dimer interface [polypeptide binding]; other site
866768012028	active site
866768012029	motif 2; other site
866768012030	motif 3; other site
866768012031	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
866768012032	L-aspartate oxidase; Provisional; Region: PRK06175
866768012033	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
866768012034	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
866768012035	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
866768012036	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
866768012037	D-subunit interface [polypeptide binding]; other site
866768012038	Iron-sulfur protein interface; other site
866768012039	proximal quinone binding site [chemical binding]; other site
866768012040	distal quinone binding site [chemical binding]; other site
866768012041	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
866768012042	Iron-sulfur protein interface; other site
866768012043	proximal quinone binding site [chemical binding]; other site
866768012044	C-subunit interface; other site
866768012045	distal quinone binding site; other site
866768012046	beta-lactamase/D-alanine carboxypeptidase; Provisional; Region: ampC; PRK11289
866768012047	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
866768012048	Bacterial lipocalin [Cell envelope biogenesis, outer membrane]; Region: Blc; COG3040
866768012049	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
866768012050	multidrug efflux system protein; Provisional; Region: PRK11431
866768012051	entericidin B membrane lipoprotein; Provisional; Region: PRK10081
866768012052	elongation factor P; Validated; Region: PRK00529
866768012053	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
866768012054	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
866768012055	RNA binding site [nucleotide binding]; other site
866768012056	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
866768012057	RNA binding site [nucleotide binding]; other site
866768012058	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
866768012059	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866768012060	FeS/SAM binding site; other site
866768012061	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
866768012062	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
866768012063	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
866768012064	ring oligomerisation interface [polypeptide binding]; other site
866768012065	ATP/Mg binding site [chemical binding]; other site
866768012066	stacking interactions; other site
866768012067	hinge regions; other site
866768012068	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
866768012069	oligomerisation interface [polypeptide binding]; other site
866768012070	mobile loop; other site
866768012071	roof hairpin; other site
866768012072	putative transporter; Provisional; Region: PRK11021
866768012073	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
866768012074	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
866768012075	Aspartase; Region: Aspartase; cd01357
866768012076	active sites [active]
866768012077	tetramer interface [polypeptide binding]; other site
866768012078	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
866768012079	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
866768012080	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
866768012081	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
866768012082	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
866768012083	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
866768012084	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
866768012085	DsbD alpha interface [polypeptide binding]; other site
866768012086	catalytic residues [active]
866768012087	putative transcriptional regulator; Provisional; Region: PRK11640
866768012088	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
866768012089	DNA-binding transcriptional activator CadC; Provisional; Region: PRK10153
866768012090	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
866768012091	DNA binding site [nucleotide binding]
866768012092	lysine/cadaverine antiporter; Provisional; Region: cadB; PRK10435
866768012093	lysine decarboxylase CadA; Provisional; Region: PRK15400
866768012094	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
866768012095	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
866768012096	homodimer interface [polypeptide binding]; other site
866768012097	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768012098	catalytic residue [active]
866768012099	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
866768012100	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
866768012101	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768012102	putative substrate translocation pore; other site
866768012103	POT family; Region: PTR2; pfam00854
866768012104	lysyl-tRNA synthetase; Reviewed; Region: PRK12445
866768012105	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
866768012106	dimer interface [polypeptide binding]; other site
866768012107	putative anticodon binding site; other site
866768012108	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
866768012109	motif 1; other site
866768012110	active site
866768012111	motif 2; other site
866768012112	motif 3; other site
866768012113	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
866768012114	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
866768012115	Predicted acetyltransferase [General function prediction only]; Region: COG2388
866768012116	Uncharacterized conserved protein [Function unknown]; Region: COG3592
866768012117	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
866768012118	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768012119	active site
866768012120	phosphorylation site [posttranslational modification]
866768012121	intermolecular recognition site; other site
866768012122	dimerization interface [polypeptide binding]; other site
866768012123	Transcriptional regulator; Region: CitT; pfam12431
866768012124	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
866768012125	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
866768012126	fumarate hydratase; Provisional; Region: PRK15389
866768012127	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
866768012128	Fumarase C-terminus; Region: Fumerase_C; pfam05683
866768012129	hypothetical protein; Provisional; Region: PRK09867
866768012130	melibiose:sodium symporter; Provisional; Region: PRK10429
866768012131	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
866768012132	alpha-galactosidase; Provisional; Region: PRK15076
866768012133	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
866768012134	NAD binding site [chemical binding]; other site
866768012135	sugar binding site [chemical binding]; other site
866768012136	divalent metal binding site [ion binding]; other site
866768012137	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
866768012138	dimer interface [polypeptide binding]; other site
866768012139	DNA-binding transcriptional regulator MelR; Provisional; Region: PRK10371
866768012140	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768012141	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768012142	arginine decarboxylase; Provisional; Region: PRK15029
866768012143	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
866768012144	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
866768012145	homodimer interface [polypeptide binding]; other site
866768012146	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768012147	catalytic residue [active]
866768012148	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
866768012149	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
866768012150	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768012151	arginine:agmatin antiporter; Provisional; Region: PRK10644
866768012152	putative metal dependent hydrolase; Provisional; Region: PRK11598
866768012153	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
866768012154	Sulfatase; Region: Sulfatase; pfam00884
866768012155	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
866768012156	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768012157	active site
866768012158	phosphorylation site [posttranslational modification]
866768012159	intermolecular recognition site; other site
866768012160	dimerization interface [polypeptide binding]; other site
866768012161	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
866768012162	DNA binding site [nucleotide binding]
866768012163	sensor protein BasS/PmrB; Provisional; Region: PRK10755
866768012164	HAMP domain; Region: HAMP; pfam00672
866768012165	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
866768012166	dimer interface [polypeptide binding]; other site
866768012167	phosphorylation site [posttranslational modification]
866768012168	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866768012169	ATP binding site [chemical binding]; other site
866768012170	Mg2+ binding site [ion binding]; other site
866768012171	G-X-G motif; other site
866768012172	proline/glycine betaine transporter; Provisional; Region: PRK10642
866768012173	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768012174	putative substrate translocation pore; other site
866768012175	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
866768012176	YjcZ-like protein; Region: YjcZ; pfam13990
866768012177	hypothetical protein; Provisional; Region: PRK09866
866768012178	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
866768012179	G1 box; other site
866768012180	GTP/Mg2+ binding site [chemical binding]; other site
866768012181	G2 box; other site
866768012182	Switch I region; other site
866768012183	G3 box; other site
866768012184	Switch II region; other site
866768012185	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
866768012186	G2 box; other site
866768012187	Switch I region; other site
866768012188	G3 box; other site
866768012189	Switch II region; other site
866768012190	G4 box; other site
866768012191	G5 box; other site
866768012192	hypothetical protein; Provisional; Region: PRK10220
866768012193	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
866768012194	PhnA protein; Region: PhnA; pfam03831
866768012195	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
866768012196	dimer interface [polypeptide binding]; other site
866768012197	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
866768012198	phosphonate/organophosphate ester transporter subunit; Provisional; Region: PRK09984
866768012199	ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Region: ABC_PhnC_transporter; cd03256
866768012200	Walker A/P-loop; other site
866768012201	ATP binding site [chemical binding]; other site
866768012202	Q-loop/lid; other site
866768012203	ABC transporter signature motif; other site
866768012204	Walker B; other site
866768012205	D-loop; other site
866768012206	H-loop/switch region; other site
866768012207	phosphonate ABC transporter, periplasmic phosphonate binding protein; Region: PhnD; TIGR03431
866768012208	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
866768012209	substrate binding pocket [chemical binding]; other site
866768012210	membrane-bound complex binding site; other site
866768012211	hinge residues; other site
866768012212	ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism]; Region: COG3639
866768012213	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768012214	dimer interface [polypeptide binding]; other site
866768012215	conserved gate region; other site
866768012216	putative PBP binding loops; other site
866768012217	ABC-ATPase subunit interface; other site
866768012218	phosphonate metabolism transcriptional regulator PhnF; Provisional; Region: PRK10079
866768012219	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
866768012220	DNA-binding site [nucleotide binding]; DNA binding site
866768012221	UTRA domain; Region: UTRA; pfam07702
866768012222	Phosphonate metabolism protein PhnG; Region: PhnG; pfam06754
866768012223	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnH; COG3625
866768012224	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnI; COG3626
866768012225	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnJ; COG3627
866768012226	phosphonate C-P lyase system protein PhnK; Provisional; Region: phnK; PRK11701
866768012227	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
866768012228	Walker A/P-loop; other site
866768012229	ATP binding site [chemical binding]; other site
866768012230	Q-loop/lid; other site
866768012231	ABC transporter signature motif; other site
866768012232	Walker B; other site
866768012233	D-loop; other site
866768012234	H-loop/switch region; other site
866768012235	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
866768012236	ABC-type phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PhnL; COG4778
866768012237	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
866768012238	Walker A/P-loop; other site
866768012239	ATP binding site [chemical binding]; other site
866768012240	Q-loop/lid; other site
866768012241	ABC transporter signature motif; other site
866768012242	Walker B; other site
866768012243	D-loop; other site
866768012244	H-loop/switch region; other site
866768012245	phosphonate metabolism protein PhnM; Provisional; Region: PRK15446
866768012246	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
866768012247	PhnM is believed to be a subunit of the membrane associated C-P lyase complex. C-P lyase is thought to catalyze the direct cleavage of inactivated C-P bonds to yield inorganic phosphate and the corresponding hydrocarbons. It is responsible for cleavage...; Region: PhnM; cd01306
866768012248	active site
866768012249	ribose 1,5-bisphosphokinase; Provisional; Region: PRK10078
866768012250	AAA domain; Region: AAA_18; pfam13238
866768012251	active site
866768012252	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
866768012253	Coenzyme A binding pocket [chemical binding]; other site
866768012254	carbon-phosphorus lyase complex accessory protein; Provisional; Region: phnP; PRK11244
866768012255	ribose 5-phosphate isomerase B; Region: rpiB; TIGR01120
866768012256	DNA-binding transcriptional repressor RpiR; Provisional; Region: PRK11337
866768012257	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
866768012258	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
866768012259	putative active site [active]
866768012260	D-allose transporter subunit; Provisional; Region: PRK09701
866768012261	Periplasmic allose-binding domain of bacterial transport systems that function as a primary receptor of active transport and chemotaxis; Region: PBP1_allose_binding; cd06320
866768012262	ligand binding site [chemical binding]; other site
866768012263	dimerization interface [polypeptide binding]; other site
866768012264	zinc binding site [ion binding]; other site
866768012265	D-allose transporter ATP-binding protein; Provisional; Region: PRK09700
866768012266	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
866768012267	Walker A/P-loop; other site
866768012268	ATP binding site [chemical binding]; other site
866768012269	Q-loop/lid; other site
866768012270	ABC transporter signature motif; other site
866768012271	Walker B; other site
866768012272	D-loop; other site
866768012273	H-loop/switch region; other site
866768012274	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
866768012275	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
866768012276	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
866768012277	TM-ABC transporter signature motif; other site
866768012278	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
866768012279	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
866768012280	substrate binding site [chemical binding]; other site
866768012281	hexamer interface [polypeptide binding]; other site
866768012282	metal binding site [ion binding]; metal-binding site
866768012283	D-allose kinase; Provisional; Region: PRK09698
866768012284	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
866768012285	nucleotide binding site [chemical binding]; other site
866768012286	Alkyl sulfatase and related hydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2015
866768012287	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
866768012288	multidrug resistance protein MdtN; Provisional; Region: PRK10476
866768012289	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
866768012290	HlyD family secretion protein; Region: HlyD_3; pfam13437
866768012291	multidrug efflux system protein MdtO; Provisional; Region: PRK11427
866768012292	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
866768012293	putative outer membrane efflux protein MdtP; Provisional; Region: PRK09915
866768012294	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
866768012295	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
866768012296	molybdopterin cofactor binding site; other site
866768012297	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
866768012298	molybdopterin cofactor binding site; other site
866768012299	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
866768012300	Sel1-like repeats; Region: SEL1; smart00671
866768012301	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
866768012302	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
866768012303	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
866768012304	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
866768012305	binding surface
866768012306	TPR motif; other site
866768012307	formate-dependent nitrite reductase complex subunit NrfF; Provisional; Region: PRK10144
866768012308	heme lyase subunit NrfE; Provisional; Region: PRK10369
866768012309	Formate-dependent nitrite reductase, membrane component [Inorganic ion transport and metabolism]; Region: NrfD; COG3301
866768012310	cytochrome c nitrite reductase, NrfD subunit; Region: cyt_nit_nrfD; TIGR03148
866768012311	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
866768012312	cytochrome c nitrite reductase pentaheme subunit; Provisional; Region: PRK11659
866768012313	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
866768012314	acetyl-CoA synthetase; Provisional; Region: PRK00174
866768012315	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
866768012316	active site
866768012317	CoA binding site [chemical binding]; other site
866768012318	acyl-activating enzyme (AAE) consensus motif; other site
866768012319	AMP binding site [chemical binding]; other site
866768012320	acetate binding site [chemical binding]; other site
866768012321	Predicted membrane protein [Function unknown]; Region: COG3162
866768012322	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
866768012323	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
866768012324	Na binding site [ion binding]; other site
866768012325	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
866768012326	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
866768012327	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
866768012328	redox-sensitivie transcriptional activator SoxR; Provisional; Region: PRK15002
866768012329	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
866768012330	DNA binding residues [nucleotide binding]
866768012331	dimer interface [polypeptide binding]; other site
866768012332	[2Fe-2S] cluster binding site [ion binding]; other site
866768012333	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
866768012334	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768012335	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
866768012336	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
866768012337	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
866768012338	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
866768012339	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
866768012340	dimer interface [polypeptide binding]; other site
866768012341	ssDNA binding site [nucleotide binding]; other site
866768012342	tetramer (dimer of dimers) interface [polypeptide binding]; other site
866768012343	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
866768012344	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
866768012345	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
866768012346	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
866768012347	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
866768012348	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
866768012349	secondary thiamine-phosphate synthase enzyme; Region: TIGR00149_YjbQ
866768012350	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866768012351	motif II; other site
866768012352	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
866768012353	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
866768012354	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768012355	homodimer interface [polypeptide binding]; other site
866768012356	catalytic residue [active]
866768012357	alanine racemase; Reviewed; Region: alr; PRK00053
866768012358	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
866768012359	active site
866768012360	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
866768012361	substrate binding site [chemical binding]; other site
866768012362	catalytic residues [active]
866768012363	dimer interface [polypeptide binding]; other site
866768012364	replicative DNA helicase; Provisional; Region: PRK08006
866768012365	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
866768012366	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
866768012367	Walker A motif; other site
866768012368	ATP binding site [chemical binding]; other site
866768012369	Walker B motif; other site
866768012370	DNA binding loops [nucleotide binding]
866768012371	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
866768012372	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
866768012373	NADP binding site [chemical binding]; other site
866768012374	dimer interface [polypeptide binding]; other site
866768012375	phage shock protein G; Reviewed; Region: pspG; PRK09459
866768012376	tRNA-dihydrouridine synthase A; Provisional; Region: PRK11815
866768012377	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
866768012378	FMN binding site [chemical binding]; other site
866768012379	active site
866768012380	catalytic residues [active]
866768012381	substrate binding site [chemical binding]; other site
866768012382	Protein of unknown function (DUF2713); Region: DUF2713; pfam10897
866768012383	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
866768012384	metal binding site 2 [ion binding]; metal-binding site
866768012385	putative DNA binding helix; other site
866768012386	metal binding site 1 [ion binding]; metal-binding site
866768012387	dimer interface [polypeptide binding]; other site
866768012388	structural Zn2+ binding site [ion binding]; other site
866768012389	hypothetical protein; Provisional; Region: PRK10428
866768012390	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
866768012391	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
866768012392	LexA repressor; Validated; Region: PRK00215
866768012393	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
866768012394	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
866768012395	Catalytic site [active]
866768012396	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
866768012397	glycerol-3-phosphate O-acyltransferase; Region: plsB; TIGR03703
866768012398	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
866768012399	putative acyl-acceptor binding pocket; other site
866768012400	4-hydroxybenzoate octaprenyltransferase; Reviewed; Region: ubiA; PRK12848
866768012401	UbiA prenyltransferase family; Region: UbiA; pfam01040
866768012402	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
866768012403	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
866768012404	SopA-like central domain; Region: SopA; pfam13981
866768012405	hypothetical protein; Validated; Region: PRK09718
866768012406	maltose regulon periplasmic protein; Provisional; Region: PRK10564
866768012407	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
866768012408	trimer interface; other site
866768012409	sugar binding site [chemical binding]; other site
866768012410	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
866768012411	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
866768012412	Walker A/P-loop; other site
866768012413	ATP binding site [chemical binding]; other site
866768012414	Q-loop/lid; other site
866768012415	ABC transporter signature motif; other site
866768012416	Walker B; other site
866768012417	D-loop; other site
866768012418	H-loop/switch region; other site
866768012419	TOBE domain; Region: TOBE_2; pfam08402
866768012420	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
866768012421	Domain of unknown function (DUF4179); Region: DUF4179; pfam13786
866768012422	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
866768012423	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768012424	dimer interface [polypeptide binding]; other site
866768012425	conserved gate region; other site
866768012426	putative PBP binding loops; other site
866768012427	ABC-ATPase subunit interface; other site
866768012428	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
866768012429	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768012430	dimer interface [polypeptide binding]; other site
866768012431	conserved gate region; other site
866768012432	putative PBP binding loops; other site
866768012433	ABC-ATPase subunit interface; other site
866768012434	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
866768012435	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768012436	putative substrate translocation pore; other site
866768012437	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768012438	phosphate-starvation-inducible protein PsiE; Provisional; Region: PRK02833
866768012439	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
866768012440	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
866768012441	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
866768012442	Protein of unknown function (DUF2886); Region: DUF2886; pfam11102
866768012443	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
866768012444	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
866768012445	active site
866768012446	dimer interface [polypeptide binding]; other site
866768012447	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
866768012448	dimer interface [polypeptide binding]; other site
866768012449	active site
866768012450	aspartate kinase III; Validated; Region: PRK09084
866768012451	AAK_AKiii-LysC-EC: Amino Acid Kinase Superfamily (AAK), AKiii-LysC-EC: this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKIII. AKIII is a monofunctional class enzyme (LysC) found in some...; Region: AAK_AKiii-LysC-EC; cd04258
866768012452	nucleotide binding site [chemical binding]; other site
866768012453	putative catalytic residues [active]
866768012454	aspartate binding site [chemical binding]; other site
866768012455	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_1; cd04932
866768012456	lysine allosteric regulatory site; other site
866768012457	dimer interface [polypeptide binding]; other site
866768012458	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
866768012459	dimer interface [polypeptide binding]; other site
866768012460	hypothetical protein; Provisional; Region: PRK10515
866768012461	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
866768012462	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
866768012463	RNA binding surface [nucleotide binding]; other site
866768012464	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
866768012465	probable active site [active]
866768012466	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
866768012467	active site pocket [active]
866768012468	oxyanion hole [active]
866768012469	catalytic triad [active]
866768012470	active site nucleophile [active]
866768012471	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
866768012472	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
866768012473	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
866768012474	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
866768012475	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
866768012476	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
866768012477	substrate binding pocket [chemical binding]; other site
866768012478	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
866768012479	B12 binding site [chemical binding]; other site
866768012480	cobalt ligand [ion binding]; other site
866768012481	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
866768012482	transcriptional repressor IclR; Provisional; Region: PRK11569
866768012483	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
866768012484	Bacterial transcriptional regulator; Region: IclR; pfam01614
866768012485	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
866768012486	bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946
866768012487	isocitrate lyase; Provisional; Region: PRK15063
866768012488	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
866768012489	tetramer interface [polypeptide binding]; other site
866768012490	active site
866768012491	Mg2+/Mn2+ binding site [ion binding]; other site
866768012492	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
866768012493	malate synthase A; Region: malate_syn_A; TIGR01344
866768012494	active site
866768012495	homoserine O-succinyltransferase; Provisional; Region: PRK05368
866768012496	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
866768012497	proposed active site lysine [active]
866768012498	conserved cys residue [active]
866768012499	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
866768012500	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
866768012501	Coenzyme A binding pocket [chemical binding]; other site
866768012502	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
866768012503	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
866768012504	purine monophosphate binding site [chemical binding]; other site
866768012505	dimer interface [polypeptide binding]; other site
866768012506	putative catalytic residues [active]
866768012507	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
866768012508	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
866768012509	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
866768012510	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
866768012511	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
866768012512	transcriptional regulatory protein ZraR; Provisional; Region: PRK10365
866768012513	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768012514	active site
866768012515	phosphorylation site [posttranslational modification]
866768012516	intermolecular recognition site; other site
866768012517	dimerization interface [polypeptide binding]; other site
866768012518	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866768012519	Walker A motif; other site
866768012520	ATP binding site [chemical binding]; other site
866768012521	Walker B motif; other site
866768012522	arginine finger; other site
866768012523	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
866768012524	sensor protein ZraS; Provisional; Region: PRK10364
866768012525	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
866768012526	dimer interface [polypeptide binding]; other site
866768012527	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866768012528	ATP binding site [chemical binding]; other site
866768012529	Mg2+ binding site [ion binding]; other site
866768012530	G-X-G motif; other site
866768012531	zinc resistance protein; Provisional; Region: zraP; PRK11546
866768012532	dimer interface [polypeptide binding]; other site
866768012533	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
866768012534	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
866768012535	IHF dimer interface [polypeptide binding]; other site
866768012536	IHF - DNA interface [nucleotide binding]; other site
866768012537	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
866768012538	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
866768012539	Active_site [active]
866768012540	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
866768012541	substrate binding site [chemical binding]; other site
866768012542	active site
866768012543	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
866768012544	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
866768012545	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
866768012546	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
866768012547	putative NADH binding site [chemical binding]; other site
866768012548	putative active site [active]
866768012549	nudix motif; other site
866768012550	putative metal binding site [ion binding]; other site
866768012551	Regulator of sigma D [Transcription]; Region: Rsd; COG3160
866768012552	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
866768012553	ThiC-associated domain; Region: ThiC-associated; pfam13667
866768012554	Thiamine biosynthesis protein ThiC [Coenzyme metabolism]; Region: ThiC; COG0422
866768012555	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
866768012556	thiamine phosphate binding site [chemical binding]; other site
866768012557	active site
866768012558	pyrophosphate binding site [ion binding]; other site
866768012559	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
866768012560	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
866768012561	ATP binding site [chemical binding]; other site
866768012562	substrate interface [chemical binding]; other site
866768012563	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
866768012564	thiS-thiF/thiG interaction site; other site
866768012565	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
866768012566	ThiS interaction site; other site
866768012567	putative active site [active]
866768012568	tetramer interface [polypeptide binding]; other site
866768012569	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
866768012570	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866768012571	FeS/SAM binding site; other site
866768012572	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
866768012573	stationary phase growth adaptation protein; Provisional; Region: PRK09717
866768012574	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
866768012575	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
866768012576	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
866768012577	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
866768012578	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
866768012579	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
866768012580	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
866768012581	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
866768012582	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
866768012583	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
866768012584	DNA binding site [nucleotide binding]
866768012585	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
866768012586	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
866768012587	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
866768012588	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
866768012589	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
866768012590	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
866768012591	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
866768012592	RPB3 interaction site [polypeptide binding]; other site
866768012593	RPB1 interaction site [polypeptide binding]; other site
866768012594	RPB11 interaction site [polypeptide binding]; other site
866768012595	RPB10 interaction site [polypeptide binding]; other site
866768012596	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
866768012597	core dimer interface [polypeptide binding]; other site
866768012598	peripheral dimer interface [polypeptide binding]; other site
866768012599	L10 interface [polypeptide binding]; other site
866768012600	L11 interface [polypeptide binding]; other site
866768012601	putative EF-Tu interaction site [polypeptide binding]; other site
866768012602	putative EF-G interaction site [polypeptide binding]; other site
866768012603	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
866768012604	23S rRNA interface [nucleotide binding]; other site
866768012605	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
866768012606	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
866768012607	mRNA/rRNA interface [nucleotide binding]; other site
866768012608	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
866768012609	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
866768012610	23S rRNA interface [nucleotide binding]; other site
866768012611	L7/L12 interface [polypeptide binding]; other site
866768012612	putative thiostrepton binding site; other site
866768012613	L25 interface [polypeptide binding]; other site
866768012614	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
866768012615	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
866768012616	putative homodimer interface [polypeptide binding]; other site
866768012617	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
866768012618	heterodimer interface [polypeptide binding]; other site
866768012619	homodimer interface [polypeptide binding]; other site
866768012620	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
866768012621	elongation factor Tu; Reviewed; Region: PRK00049
866768012622	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
866768012623	G1 box; other site
866768012624	GEF interaction site [polypeptide binding]; other site
866768012625	GTP/Mg2+ binding site [chemical binding]; other site
866768012626	Switch I region; other site
866768012627	G2 box; other site
866768012628	G3 box; other site
866768012629	Switch II region; other site
866768012630	G4 box; other site
866768012631	G5 box; other site
866768012632	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
866768012633	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
866768012634	Antibiotic Binding Site [chemical binding]; other site
866768012635	pantothenate kinase; Provisional; Region: PRK05439
866768012636	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
866768012637	ATP-binding site [chemical binding]; other site
866768012638	CoA-binding site [chemical binding]; other site
866768012639	Mg2+-binding site [ion binding]; other site
866768012640	Biotin operon repressor [Transcription]; Region: BirA; COG1654
866768012641	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
866768012642	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
866768012643	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
866768012644	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
866768012645	FAD binding domain; Region: FAD_binding_4; pfam01565
866768012646	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
866768012647	glutamate racemase; Provisional; Region: PRK00865
866768012648	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
866768012649	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768012650	S-adenosylmethionine binding site [chemical binding]; other site
866768012651	hypothetical protein; Provisional; Region: PRK11056
866768012652	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
866768012653	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
866768012654	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
866768012655	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
866768012656	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
866768012657	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
866768012658	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768012659	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
866768012660	dimerization interface [polypeptide binding]; other site
866768012661	argininosuccinate lyase; Provisional; Region: PRK04833
866768012662	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
866768012663	active sites [active]
866768012664	tetramer interface [polypeptide binding]; other site
866768012665	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
866768012666	nucleotide binding site [chemical binding]; other site
866768012667	N-acetyl-L-glutamate binding site [chemical binding]; other site
866768012668	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
866768012669	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
866768012670	acetylornithine deacetylase; Provisional; Region: PRK05111
866768012671	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
866768012672	metal binding site [ion binding]; metal-binding site
866768012673	putative dimer interface [polypeptide binding]; other site
866768012674	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
866768012675	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
866768012676	hypothetical protein; Provisional; Region: PRK10649
866768012677	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
866768012678	Sulfatase; Region: Sulfatase; pfam00884
866768012679	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
866768012680	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768012681	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
866768012682	active site
866768012683	P-loop; other site
866768012684	phosphorylation site [posttranslational modification]
866768012685	pyruvate formate lyase II activase; Provisional; Region: PRK10076
866768012686	putative formate acetyltransferase 2; Provisional; Region: pflD; PRK09983
866768012687	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
866768012688	dimer interface [polypeptide binding]; other site
866768012689	active site
866768012690	glycine loop; other site
866768012691	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
866768012692	active site
866768012693	P-loop; other site
866768012694	phosphorylation site [posttranslational modification]
866768012695	putative PTS system fructose-like transporter subunit EIIC; Provisional; Region: PRK10478
866768012696	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
866768012697	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
866768012698	dimerization domain swap beta strand [polypeptide binding]; other site
866768012699	regulatory protein interface [polypeptide binding]; other site
866768012700	active site
866768012701	regulatory phosphorylation site [posttranslational modification]; other site
866768012702	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
866768012703	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
866768012704	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
866768012705	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
866768012706	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
866768012707	active site
866768012708	phosphorylation site [posttranslational modification]
866768012709	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
866768012710	active site
866768012711	intersubunit interactions; other site
866768012712	catalytic residue [active]
866768012713	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
866768012714	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
866768012715	dimer interface [polypeptide binding]; other site
866768012716	active site
866768012717	metal binding site [ion binding]; metal-binding site
866768012718	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3738
866768012719	EamA-like transporter family; Region: EamA; pfam00892
866768012720	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
866768012721	EamA-like transporter family; Region: EamA; pfam00892
866768012722	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
866768012723	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
866768012724	heme binding site [chemical binding]; other site
866768012725	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
866768012726	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
866768012727	FAD binding site [chemical binding]; other site
866768012728	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
866768012729	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
866768012730	putative catalytic residues [active]
866768012731	putative nucleotide binding site [chemical binding]; other site
866768012732	putative aspartate binding site [chemical binding]; other site
866768012733	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
866768012734	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
866768012735	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
866768012736	cystathionine gamma-synthase; Provisional; Region: PRK08045
866768012737	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
866768012738	homodimer interface [polypeptide binding]; other site
866768012739	substrate-cofactor binding pocket; other site
866768012740	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768012741	catalytic residue [active]
866768012742	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
866768012743	dimerization interface [polypeptide binding]; other site
866768012744	DNA binding site [nucleotide binding]
866768012745	corepressor binding sites; other site
866768012746	hypothetical protein; Provisional; Region: PRK10030
866768012747	Protein of unknown function (DUF2459); Region: DUF2459; cl09819
866768012748	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
866768012749	primosome assembly protein PriA; Validated; Region: PRK05580
866768012750	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
866768012751	ATP binding site [chemical binding]; other site
866768012752	putative Mg++ binding site [ion binding]; other site
866768012753	helicase superfamily c-terminal domain; Region: HELICc; smart00490
866768012754	ATP-binding site [chemical binding]; other site
866768012755	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
866768012756	DNA binding site [nucleotide binding]
866768012757	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
866768012758	domain linker motif; other site
866768012759	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
866768012760	dimerization interface [polypeptide binding]; other site
866768012761	ligand binding site [chemical binding]; other site
866768012762	essential cell division protein FtsN; Provisional; Region: PRK10927
866768012763	cell division protein FtsN; Provisional; Region: PRK12757
866768012764	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
866768012765	active site
866768012766	HslU subunit interaction site [polypeptide binding]; other site
866768012767	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
866768012768	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866768012769	Walker A motif; other site
866768012770	ATP binding site [chemical binding]; other site
866768012771	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
866768012772	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
866768012773	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Region: menA; TIGR00751
866768012774	UbiA prenyltransferase family; Region: UbiA; pfam01040
866768012775	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
866768012776	septal ring assembly protein ZapB; Provisional; Region: PRK15422
866768012777	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
866768012778	amphipathic channel; other site
866768012779	Asn-Pro-Ala signature motifs; other site
866768012780	glycerol kinase; Provisional; Region: glpK; PRK00047
866768012781	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
866768012782	N- and C-terminal domain interface [polypeptide binding]; other site
866768012783	active site
866768012784	MgATP binding site [chemical binding]; other site
866768012785	catalytic site [active]
866768012786	metal binding site [ion binding]; metal-binding site
866768012787	glycerol binding site [chemical binding]; other site
866768012788	homotetramer interface [polypeptide binding]; other site
866768012789	homodimer interface [polypeptide binding]; other site
866768012790	FBP binding site [chemical binding]; other site
866768012791	protein IIAGlc interface [polypeptide binding]; other site
866768012792	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
866768012793	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
866768012794	putative active site [active]
866768012795	ferredoxin-NADP reductase; Provisional; Region: PRK10926
866768012796	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
866768012797	FAD binding pocket [chemical binding]; other site
866768012798	FAD binding motif [chemical binding]; other site
866768012799	phosphate binding motif [ion binding]; other site
866768012800	beta-alpha-beta structure motif; other site
866768012801	NAD binding pocket [chemical binding]; other site
866768012802	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
866768012803	Ligand Binding Site [chemical binding]; other site
866768012804	hypothetical protein; Provisional; Region: PRK09981
866768012805	Predicted membrane protein [Function unknown]; Region: COG3152
866768012806	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
866768012807	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
866768012808	triosephosphate isomerase; Provisional; Region: PRK14567
866768012809	substrate binding site [chemical binding]; other site
866768012810	dimer interface [polypeptide binding]; other site
866768012811	catalytic triad [active]
866768012812	CDP-diacylglycerol pyrophosphatase, bacterial type; Region: cdh; TIGR00672
866768012813	sulfate transporter subunit; Provisional; Region: PRK10752
866768012814	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
866768012815	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
866768012816	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
866768012817	active site
866768012818	ADP/pyrophosphate binding site [chemical binding]; other site
866768012819	dimerization interface [polypeptide binding]; other site
866768012820	allosteric effector site; other site
866768012821	fructose-1,6-bisphosphate binding site; other site
866768012822	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
866768012823	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
866768012824	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
866768012825	dimer interface [polypeptide binding]; other site
866768012826	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
866768012827	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768012828	active site
866768012829	intermolecular recognition site; other site
866768012830	dimerization interface [polypeptide binding]; other site
866768012831	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
866768012832	DNA binding site [nucleotide binding]
866768012833	two-component sensor protein; Provisional; Region: cpxA; PRK09470
866768012834	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
866768012835	dimerization interface [polypeptide binding]; other site
866768012836	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
866768012837	dimer interface [polypeptide binding]; other site
866768012838	phosphorylation site [posttranslational modification]
866768012839	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866768012840	ATP binding site [chemical binding]; other site
866768012841	Mg2+ binding site [ion binding]; other site
866768012842	G-X-G motif; other site
866768012843	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
866768012844	MOSC domain; Region: MOSC; pfam03473
866768012845	3-alpha domain; Region: 3-alpha; pfam03475
866768012846	2-keto-3-deoxygluconate transporter; Region: kdgT; TIGR00793
866768012847	superoxide dismutase; Provisional; Region: PRK10925
866768012848	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
866768012849	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
866768012850	L-rhamnose-proton symport protein (RhaT); Region: RhaT; cl05728
866768012851	RhaT L-rhamnose-proton symporter family protein; Region: RhaT; TIGR00776
866768012852	transcriptional activator RhaR; Provisional; Region: PRK13500
866768012853	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
866768012854	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768012855	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768012856	transcriptional activator RhaS; Provisional; Region: PRK13503
866768012857	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
866768012858	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768012859	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
866768012860	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
866768012861	N- and C-terminal domain interface [polypeptide binding]; other site
866768012862	active site
866768012863	putative catalytic site [active]
866768012864	metal binding site [ion binding]; metal-binding site
866768012865	ATP binding site [chemical binding]; other site
866768012866	rhamnulokinase; Provisional; Region: rhaB; PRK10640
866768012867	carbohydrate binding site [chemical binding]; other site
866768012868	L-rhamnose isomerase; Provisional; Region: PRK01076
866768012869	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
866768012870	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
866768012871	intersubunit interface [polypeptide binding]; other site
866768012872	active site
866768012873	Zn2+ binding site [ion binding]; other site
866768012874	L-rhamnose 1-epimerase; Region: YiiL_rotase; TIGR02625
866768012875	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
866768012876	active site
866768012877	phosphorylation site [posttranslational modification]
866768012878	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
866768012879	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
866768012880	active site
866768012881	P-loop; other site
866768012882	phosphorylation site [posttranslational modification]
866768012883	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
866768012884	putative peptidase; Provisional; Region: PRK09864
866768012885	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
866768012886	oligomer interface [polypeptide binding]; other site
866768012887	active site
866768012888	metal binding site [ion binding]; metal-binding site
866768012889	putative frv operon regulatory protein; Provisional; Region: PRK09863
866768012890	HTH domain; Region: HTH_11; pfam08279
866768012891	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
866768012892	active site
866768012893	phosphorylation site [posttranslational modification]
866768012894	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
866768012895	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
866768012896	formate dehydrogenase, alpha subunit, proteobacterial-type; Region: formate-DH-alph; TIGR01553
866768012897	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
866768012898	[4Fe-4S] binding site [ion binding]; other site
866768012899	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
866768012900	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
866768012901	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
866768012902	molybdopterin cofactor binding site; other site
866768012903	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
866768012904	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
866768012905	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
866768012906	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
866768012907	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
866768012908	formate dehydrogenase accessory protein FdhE; Region: FdhE; TIGR01562
866768012909	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
866768012910	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
866768012911	Coenzyme A binding pocket [chemical binding]; other site
866768012912	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
866768012913	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
866768012914	putative active site [active]
866768012915	dimerization interface [polypeptide binding]; other site
866768012916	putative tRNAtyr binding site [nucleotide binding]; other site
866768012917	hypothetical protein; Reviewed; Region: PRK01637
866768012918	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
866768012919	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866768012920	motif II; other site
866768012921	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
866768012922	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
866768012923	putative DNA binding site [nucleotide binding]; other site
866768012924	putative Zn2+ binding site [ion binding]; other site
866768012925	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
866768012926	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
866768012927	Ribokinase-like subgroup B.  Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_B; cd01945
866768012928	substrate binding site [chemical binding]; other site
866768012929	ATP binding site [chemical binding]; other site
866768012930	NADH-dependent gamma-hydroxybutyrate dehydrogenase; Provisional; Region: PRK15461
866768012931	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
866768012932	Tagatose-1,6-bisphosphate aldolase [Carbohydrate transport and metabolism]; Region: LacD; COG3684
866768012933	catalytic residue [active]
866768012934	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cd00249
866768012935	dimerization interface [polypeptide binding]; other site
866768012936	putative active cleft [active]
866768012937	Aldose 1-epimerase, similar to Escherichia coli YihR; Region: Aldose_epim_Ec_YihR; cd09022
866768012938	active site
866768012939	catalytic residues [active]
866768012940	alpha-glucosidase; Provisional; Region: PRK10426
866768012941	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
866768012942	YihQ is a bacterial alpha-glucosidase with a conserved glycosyl hydrolase family 31 (GH31) domain that catalyzes the release of an alpha-glucosyl residue from the non-reducing end of alpha-glucoside substrates such as alpha-glucosyl fluoride. Orthologs...; Region: GH31_glucosidase_YihQ; cd06594
866768012943	putative active site [active]
866768012944	putative catalytic site [active]
866768012945	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
866768012946	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
866768012947	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
866768012948	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768012949	putative substrate translocation pore; other site
866768012950	outer membrane porin L; Provisional; Region: ompL; PRK09980
866768012951	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768012952	putative substrate translocation pore; other site
866768012953	phosphoglycerate transporter family protein; Region: 2A0104; TIGR00881
866768012954	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
866768012955	transcriptional regulator protein; Region: phnR; TIGR03337
866768012956	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
866768012957	DNA-binding site [nucleotide binding]; DNA binding site
866768012958	UTRA domain; Region: UTRA; pfam07702
866768012959	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
866768012960	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
866768012961	G1 box; other site
866768012962	putative GEF interaction site [polypeptide binding]; other site
866768012963	GTP/Mg2+ binding site [chemical binding]; other site
866768012964	Switch I region; other site
866768012965	G2 box; other site
866768012966	G3 box; other site
866768012967	Switch II region; other site
866768012968	G4 box; other site
866768012969	G5 box; other site
866768012970	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
866768012971	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
866768012972	glutamine synthetase; Provisional; Region: glnA; PRK09469
866768012973	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
866768012974	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
866768012975	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
866768012976	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
866768012977	putative active site [active]
866768012978	heme pocket [chemical binding]; other site
866768012979	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
866768012980	dimer interface [polypeptide binding]; other site
866768012981	phosphorylation site [posttranslational modification]
866768012982	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
866768012983	ATP binding site [chemical binding]; other site
866768012984	Mg2+ binding site [ion binding]; other site
866768012985	G-X-G motif; other site
866768012986	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
866768012987	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
866768012988	active site
866768012989	phosphorylation site [posttranslational modification]
866768012990	intermolecular recognition site; other site
866768012991	dimerization interface [polypeptide binding]; other site
866768012992	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866768012993	Walker A motif; other site
866768012994	ATP binding site [chemical binding]; other site
866768012995	Walker B motif; other site
866768012996	arginine finger; other site
866768012997	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
866768012998	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
866768012999	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866768013000	FeS/SAM binding site; other site
866768013001	HemN C-terminal domain; Region: HemN_C; pfam06969
866768013002	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3078
866768013003	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
866768013004	G1 box; other site
866768013005	GTP/Mg2+ binding site [chemical binding]; other site
866768013006	Switch I region; other site
866768013007	G2 box; other site
866768013008	G3 box; other site
866768013009	Switch II region; other site
866768013010	G4 box; other site
866768013011	G5 box; other site
866768013012	DNA polymerase I; Provisional; Region: PRK05755
866768013013	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
866768013014	active site
866768013015	metal binding site 1 [ion binding]; metal-binding site
866768013016	putative 5' ssDNA interaction site; other site
866768013017	metal binding site 3; metal-binding site
866768013018	metal binding site 2 [ion binding]; metal-binding site
866768013019	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
866768013020	putative DNA binding site [nucleotide binding]; other site
866768013021	putative metal binding site [ion binding]; other site
866768013022	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
866768013023	active site
866768013024	catalytic site [active]
866768013025	substrate binding site [chemical binding]; other site
866768013026	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
866768013027	active site
866768013028	DNA binding site [nucleotide binding]
866768013029	catalytic site [active]
866768013030	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
866768013031	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
866768013032	putative acyl-acceptor binding pocket; other site
866768013033	hypothetical protein; Provisional; Region: PRK11367
866768013034	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
866768013035	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
866768013036	Putative homoserine kinase type II (protein kinase fold) [General function prediction only]; Region: COG2334
866768013037	serine/threonine protein kinase; Provisional; Region: PRK11768
866768013038	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
866768013039	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
866768013040	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
866768013041	GTP binding site; other site
866768013042	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
866768013043	Walker A motif; other site
866768013044	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
866768013045	potassium transporter; Provisional; Region: PRK10750
866768013046	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
866768013047	hypothetical protein; Provisional; Region: PRK11568
866768013048	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
866768013049	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
866768013050	proline dipeptidase; Provisional; Region: PRK13607
866768013051	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
866768013052	active site
866768013053	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
866768013054	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
866768013055	substrate binding site [chemical binding]; other site
866768013056	oxyanion hole (OAH) forming residues; other site
866768013057	trimer interface [polypeptide binding]; other site
866768013058	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
866768013059	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
866768013060	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
866768013061	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
866768013062	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
866768013063	dimer interface [polypeptide binding]; other site
866768013064	active site
866768013065	FMN reductase; Validated; Region: fre; PRK08051
866768013066	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
866768013067	FAD binding pocket [chemical binding]; other site
866768013068	FAD binding motif [chemical binding]; other site
866768013069	phosphate binding motif [ion binding]; other site
866768013070	beta-alpha-beta structure motif; other site
866768013071	NAD binding pocket [chemical binding]; other site
866768013072	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
866768013073	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
866768013074	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
866768013075	KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); Region: KOW; cl00354
866768013076	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
866768013077	active site
866768013078	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
866768013079	sec-independent translocase; Provisional; Region: PRK01770
866768013080	sec-independent translocase; Provisional; Region: tatB; PRK00404
866768013081	twin arginine translocase protein A; Provisional; Region: tatA; PRK03554
866768013082	twin arginine translocase protein A; Provisional; Region: tatA; PRK00575
866768013083	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
866768013084	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
866768013085	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
866768013086	SCP-2 sterol transfer family; Region: SCP2; pfam02036
866768013087	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
866768013088	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768013089	S-adenosylmethionine binding site [chemical binding]; other site
866768013090	DNA recombination protein RmuC; Provisional; Region: PRK10361
866768013091	RmuC family; Region: RmuC; pfam02646
866768013092	Transcriptional regulator [Transcription]; Region: IclR; COG1414
866768013093	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
866768013094	Bacterial transcriptional regulator; Region: IclR; pfam01614
866768013095	2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]; Region: DgoK; COG3734
866768013096	2-keto-3-deoxy-galactonokinase; Region: DGOK; pfam05035
866768013097	2-dehydro-3-deoxy-6-phosphogalactonate aldolase; Reviewed; Region: PRK09140
866768013098	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
866768013099	active site
866768013100	intersubunit interface [polypeptide binding]; other site
866768013101	catalytic residue [active]
866768013102	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3181
866768013103	Tripartite tricarboxylate transporter TctB family; Region: TctB; pfam07331
866768013104	Tripartite tricarboxylate transporter TctA family; Region: TctA; cl00772
866768013105	uridine phosphorylase; Provisional; Region: PRK11178
866768013106	uridine phosphorylase; Region: Uridine-psphlse; TIGR01718
866768013107	Dienelactone hydrolase family; Region: DLH; pfam01738
866768013108	BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840
866768013109	Isochorismatase family; Region: Isochorismatase; pfam00857
866768013110	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
866768013111	catalytic triad [active]
866768013112	conserved cis-peptide bond; other site
866768013113	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
866768013114	membrane protein FdrA; Validated; Region: PRK06091
866768013115	CoA binding domain; Region: CoA_binding; pfam02629
866768013116	CoA-ligase; Region: Ligase_CoA; pfam00549
866768013117	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
866768013118	carbamate kinase; Reviewed; Region: PRK12686
866768013119	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
866768013120	putative substrate binding site [chemical binding]; other site
866768013121	nucleotide binding site [chemical binding]; other site
866768013122	nucleotide binding site [chemical binding]; other site
866768013123	homodimer interface [polypeptide binding]; other site
866768013124	allophanate hydrolase; Provisional; Region: PRK08186
866768013125	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
866768013126	Na binding site [ion binding]; other site
866768013127	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
866768013128	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768013129	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
866768013130	dimerization interface [polypeptide binding]; other site
866768013131	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
866768013132	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
866768013133	THF binding site; other site
866768013134	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
866768013135	substrate binding site [chemical binding]; other site
866768013136	THF binding site; other site
866768013137	zinc-binding site [ion binding]; other site
866768013138	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
866768013139	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768013140	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
866768013141	putative dimerization interface [polypeptide binding]; other site
866768013142	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
866768013143	EamA-like transporter family; Region: EamA; pfam00892
866768013144	putative hydrolase; Provisional; Region: PRK10976
866768013145	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866768013146	active site
866768013147	motif I; other site
866768013148	motif II; other site
866768013149	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866768013150	lysophospholipase L2; Provisional; Region: PRK10749
866768013151	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
866768013152	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
866768013153	threonine efflux system; Provisional; Region: PRK10229
866768013154	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
866768013155	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
866768013156	ATP binding site [chemical binding]; other site
866768013157	putative Mg++ binding site [ion binding]; other site
866768013158	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
866768013159	nucleotide binding region [chemical binding]; other site
866768013160	ATP-binding site [chemical binding]; other site
866768013161	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
866768013162	Helicase and RNase D C-terminal; Region: HRDC; smart00341
866768013163	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
866768013164	dimerization interface [polypeptide binding]; other site
866768013165	substrate binding site [chemical binding]; other site
866768013166	active site
866768013167	calcium binding site [ion binding]; other site
866768013168	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
866768013169	CoenzymeA binding site [chemical binding]; other site
866768013170	subunit interaction site [polypeptide binding]; other site
866768013171	PHB binding site; other site
866768013172	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
866768013173	EamA-like transporter family; Region: EamA; cl17759
866768013174	Protein of unknown function (DUF2628); Region: DUF2628; pfam10947
866768013175	Protein of unknown function (DUF3289); Region: DUF3289; cl11840
866768013176	Enterobacterial putative membrane protein (DUF943); Region: DUF943; pfam06092
866768013177	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
866768013178	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
866768013179	Cl binding site [ion binding]; other site
866768013180	oligomer interface [polypeptide binding]; other site
866768013181	Predicted periplasmic protein [Function unknown]; Region: COG3698
866768013182	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
866768013183	Uncharacterized conserved protein [Function unknown]; Region: COG1912
866768013184	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
866768013185	Part of AAA domain; Region: AAA_19; pfam13245
866768013186	Family description; Region: UvrD_C_2; pfam13538
866768013187	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
866768013188	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866768013189	motif II; other site
866768013190	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
866768013191	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
866768013192	active site
866768013193	DNA binding site [nucleotide binding]
866768013194	Int/Topo IB signature motif; other site
866768013195	hypothetical protein; Provisional; Region: PRK10963
866768013196	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
866768013197	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
866768013198	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
866768013199	Predicted small periplasmic lipoprotein [Cell motility and secretion]; Region: COG5567
866768013200	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
866768013201	putative iron binding site [ion binding]; other site
866768013202	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
866768013203	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
866768013204	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
866768013205	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
866768013206	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
866768013207	domain interfaces; other site
866768013208	active site
866768013209	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
866768013210	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
866768013211	active site
866768013212	Uncharacterized enzyme of heme biosynthesis [Coenzyme metabolism]; Region: HemX; COG2959
866768013213	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
866768013214	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
866768013215	HemY protein N-terminus; Region: HemY_N; pfam07219
866768013216	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
866768013217	Sulfatase; Region: Sulfatase; pfam00884
866768013218	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
866768013219	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
866768013220	FeS/SAM binding site; other site
866768013221	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
866768013222	putative transport protein YifK; Provisional; Region: PRK10746
866768013223	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
866768013224	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
866768013225	putative common antigen polymerase; Provisional; Region: PRK02975
866768013226	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
866768013227	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
866768013228	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
866768013229	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
866768013230	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
866768013231	inhibitor-cofactor binding pocket; inhibition site
866768013232	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768013233	catalytic residue [active]
866768013234	TDP-fucosamine acetyltransferase; Provisional; Region: PRK10975
866768013235	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
866768013236	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
866768013237	substrate binding site; other site
866768013238	tetramer interface; other site
866768013239	dTDP-glucose 4,6-dehydratase; Provisional; Region: PRK10217
866768013240	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
866768013241	NAD binding site [chemical binding]; other site
866768013242	substrate binding site [chemical binding]; other site
866768013243	homodimer interface [polypeptide binding]; other site
866768013244	active site
866768013245	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
866768013246	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
866768013247	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
866768013248	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
866768013249	UDP-N-acetylglucosamine 2-epimerase; Region: wecB; TIGR00236
866768013250	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
866768013251	active site
866768013252	homodimer interface [polypeptide binding]; other site
866768013253	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
866768013254	Chain length determinant protein; Region: Wzz; pfam02706
866768013255	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase; Provisional; Region: PRK15119
866768013256	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
866768013257	Mg++ binding site [ion binding]; other site
866768013258	putative catalytic motif [active]
866768013259	substrate binding site [chemical binding]; other site
866768013260	transcription termination factor Rho; Provisional; Region: rho; PRK09376
866768013261	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
866768013262	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
866768013263	RNA binding site [nucleotide binding]; other site
866768013264	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
866768013265	multimer interface [polypeptide binding]; other site
866768013266	Walker A motif; other site
866768013267	ATP binding site [chemical binding]; other site
866768013268	Walker B motif; other site
866768013269	putative rho operon leader peptide; Provisional; Region: PRK09979
866768013270	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
866768013271	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
866768013272	catalytic residues [active]
866768013273	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
866768013274	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
866768013275	ATP binding site [chemical binding]; other site
866768013276	Mg++ binding site [ion binding]; other site
866768013277	motif III; other site
866768013278	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
866768013279	nucleotide binding region [chemical binding]; other site
866768013280	ATP-binding site [chemical binding]; other site
866768013281	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
866768013282	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
866768013283	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
866768013284	Part of AAA domain; Region: AAA_19; pfam13245
866768013285	Family description; Region: UvrD_C_2; pfam13538
866768013286	peptidyl-prolyl cis-trans isomerase C; Provisional; Region: PRK15441
866768013287	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
866768013288	ketol-acid reductoisomerase; Validated; Region: PRK05225
866768013289	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
866768013290	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
866768013291	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
866768013292	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768013293	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
866768013294	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
866768013295	putative dimerization interface [polypeptide binding]; other site
866768013296	threonine dehydratase; Reviewed; Region: PRK09224
866768013297	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
866768013298	tetramer interface [polypeptide binding]; other site
866768013299	pyridoxal 5'-phosphate binding site [chemical binding]; other site
866768013300	catalytic residue [active]
866768013301	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
866768013302	putative Ile/Val binding site [chemical binding]; other site
866768013303	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
866768013304	putative Ile/Val binding site [chemical binding]; other site
866768013305	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
866768013306	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
866768013307	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
866768013308	homodimer interface [polypeptide binding]; other site
866768013309	substrate-cofactor binding pocket; other site
866768013310	catalytic residue [active]
866768013311	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
866768013312	acetolactate synthase 2 catalytic subunit; Reviewed; Region: PRK08978
866768013313	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
866768013314	PYR/PP interface [polypeptide binding]; other site
866768013315	dimer interface [polypeptide binding]; other site
866768013316	TPP binding site [chemical binding]; other site
866768013317	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
866768013318	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
866768013319	TPP-binding site [chemical binding]; other site
866768013320	dimer interface [polypeptide binding]; other site
866768013321	putative ATP-dependent protease; Provisional; Region: PRK09862
866768013322	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
866768013323	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866768013324	Walker A motif; other site
866768013325	ATP binding site [chemical binding]; other site
866768013326	Walker B motif; other site
866768013327	arginine finger; other site
866768013328	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
866768013329	hypothetical protein; Provisional; Region: PRK11027
866768013330	transcriptional regulator HdfR; Provisional; Region: PRK03601
866768013331	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768013332	LysR substrate binding domain; Region: LysR_substrate; pfam03466
866768013333	dimerization interface [polypeptide binding]; other site
866768013334	Transcriptional regulators [Transcription]; Region: FadR; COG2186
866768013335	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
866768013336	DNA-binding site [nucleotide binding]; DNA binding site
866768013337	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
866768013338	putative transporter; Provisional; Region: PRK10504
866768013339	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768013340	putative substrate translocation pore; other site
866768013341	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768013342	transcriptional repressor RbsR; Provisional; Region: PRK10423
866768013343	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
866768013344	DNA binding site [nucleotide binding]
866768013345	domain linker motif; other site
866768013346	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
866768013347	dimerization interface [polypeptide binding]; other site
866768013348	ligand binding site [chemical binding]; other site
866768013349	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
866768013350	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
866768013351	substrate binding site [chemical binding]; other site
866768013352	dimer interface [polypeptide binding]; other site
866768013353	ATP binding site [chemical binding]; other site
866768013354	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
866768013355	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
866768013356	ligand binding site [chemical binding]; other site
866768013357	dimerization interface [polypeptide binding]; other site
866768013358	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
866768013359	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
866768013360	TM-ABC transporter signature motif; other site
866768013361	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
866768013362	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
866768013363	Walker A/P-loop; other site
866768013364	ATP binding site [chemical binding]; other site
866768013365	Q-loop/lid; other site
866768013366	ABC transporter signature motif; other site
866768013367	Walker B; other site
866768013368	D-loop; other site
866768013369	H-loop/switch region; other site
866768013370	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
866768013371	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
866768013372	Helix-turn-helix domain; Region: HTH_28; pfam13518
866768013373	Helix-turn-helix domain; Region: HTH_28; pfam13518
866768013374	putative transposase OrfB; Reviewed; Region: PHA02517
866768013375	HTH-like domain; Region: HTH_21; pfam13276
866768013376	Integrase core domain; Region: rve; pfam00665
866768013377	Integrase core domain; Region: rve_2; pfam13333
866768013378	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
866768013379	potassium uptake protein; Region: kup; TIGR00794
866768013380	regulatory ATPase RavA; Provisional; Region: PRK13531
866768013381	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
866768013382	Walker A motif; other site
866768013383	ATP binding site [chemical binding]; other site
866768013384	Walker B motif; other site
866768013385	arginine finger; other site
866768013386	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
866768013387	hypothetical protein; Provisional; Region: yieM; PRK10997
866768013388	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
866768013389	metal ion-dependent adhesion site (MIDAS); other site
866768013390	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
866768013391	dimer interface [polypeptide binding]; other site
866768013392	active site
866768013393	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
866768013394	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
866768013395	putative DNA binding site [nucleotide binding]; other site
866768013396	putative Zn2+ binding site [ion binding]; other site
866768013397	AsnC family; Region: AsnC_trans_reg; pfam01037
866768013398	FMN-binding protein MioC; Provisional; Region: PRK09004
866768013399	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
866768013400	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
866768013401	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
866768013402	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
866768013403	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
866768013404	S-adenosylmethionine binding site [chemical binding]; other site
866768013405	F0F1 ATP synthase subunit I; Validated; Region: PRK08049
866768013406	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
866768013407	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
866768013408	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
866768013409	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
866768013410	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
866768013411	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
866768013412	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
866768013413	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
866768013414	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
866768013415	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
866768013416	beta subunit interaction interface [polypeptide binding]; other site
866768013417	Walker A motif; other site
866768013418	ATP binding site [chemical binding]; other site
866768013419	Walker B motif; other site
866768013420	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
866768013421	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
866768013422	core domain interface [polypeptide binding]; other site
866768013423	delta subunit interface [polypeptide binding]; other site
866768013424	epsilon subunit interface [polypeptide binding]; other site
866768013425	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
866768013426	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
866768013427	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
866768013428	alpha subunit interaction interface [polypeptide binding]; other site
866768013429	Walker A motif; other site
866768013430	ATP binding site [chemical binding]; other site
866768013431	Walker B motif; other site
866768013432	inhibitor binding site; inhibition site
866768013433	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
866768013434	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
866768013435	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
866768013436	gamma subunit interface [polypeptide binding]; other site
866768013437	epsilon subunit interface [polypeptide binding]; other site
866768013438	LBP interface [polypeptide binding]; other site
866768013439	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
866768013440	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
866768013441	Substrate binding site; other site
866768013442	Mg++ binding site; other site
866768013443	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
866768013444	active site
866768013445	substrate binding site [chemical binding]; other site
866768013446	CoA binding site [chemical binding]; other site
866768013447	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
866768013448	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
866768013449	glutaminase active site [active]
866768013450	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
866768013451	dimer interface [polypeptide binding]; other site
866768013452	active site
866768013453	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
866768013454	dimer interface [polypeptide binding]; other site
866768013455	active site
866768013456	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
866768013457	phosphate transporter permease subunit PstC; Provisional; Region: pstC; PRK11275
866768013458	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768013459	dimer interface [polypeptide binding]; other site
866768013460	conserved gate region; other site
866768013461	putative PBP binding loops; other site
866768013462	ABC-ATPase subunit interface; other site
866768013463	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
866768013464	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
866768013465	dimer interface [polypeptide binding]; other site
866768013466	conserved gate region; other site
866768013467	putative PBP binding loops; other site
866768013468	ABC-ATPase subunit interface; other site
866768013469	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
866768013470	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
866768013471	Walker A/P-loop; other site
866768013472	ATP binding site [chemical binding]; other site
866768013473	Q-loop/lid; other site
866768013474	ABC transporter signature motif; other site
866768013475	Walker B; other site
866768013476	D-loop; other site
866768013477	H-loop/switch region; other site
866768013478	transcriptional regulator PhoU; Provisional; Region: PRK11115
866768013479	PhoU domain; Region: PhoU; pfam01895
866768013480	PhoU domain; Region: PhoU; pfam01895
866768013481	transcriptional antiterminator BglG; Provisional; Region: PRK09772
866768013482	CAT RNA binding domain; Region: CAT_RBD; pfam03123
866768013483	PRD domain; Region: PRD; pfam00874
866768013484	PRD domain; Region: PRD; pfam00874
866768013485	PTS system beta-glucoside-specific transporter subunits IIABC; Provisional; Region: PRK09824
866768013486	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
866768013487	active site turn [active]
866768013488	phosphorylation site [posttranslational modification]
866768013489	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
866768013490	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
866768013491	HPr interaction site; other site
866768013492	glycerol kinase (GK) interaction site [polypeptide binding]; other site
866768013493	active site
866768013494	phosphorylation site [posttranslational modification]
866768013495	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
866768013496	beta-galactosidase; Region: BGL; TIGR03356
866768013497	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
866768013498	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
866768013499	trimer interface; other site
866768013500	sugar binding site [chemical binding]; other site
866768013501	N-terminal Early set domain associated with the catalytic domain of putative esterases; Region: E_set_Esterase_like_N; cd11294
866768013502	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
866768013503	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
866768013504	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
866768013505	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
866768013506	active site
866768013507	trimer interface [polypeptide binding]; other site
866768013508	allosteric site; other site
866768013509	active site lid [active]
866768013510	Uncharacterized protein family (UPF0167); Region: UPF0167; cl01252
866768013511	putative inner membrane protein; Provisional; Region: PRK09823
866768013512	6-phosphogluconate phosphatase; Provisional; Region: PRK10563
866768013513	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
866768013514	active site
866768013515	motif I; other site
866768013516	motif II; other site
866768013517	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
866768013518	Predicted flavoprotein [General function prediction only]; Region: COG0431
866768013519	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
866768013520	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
866768013521	DNA-binding transcriptional regulator YidZ; Provisional; Region: PRK10216
866768013522	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
866768013523	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
866768013524	substrate binding pocket [chemical binding]; other site
866768013525	dimerization interface [polypeptide binding]; other site
866768013526	multidrug efflux system protein MdtL; Provisional; Region: PRK10473
866768013527	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
866768013528	putative substrate translocation pore; other site
866768013529	tryptophan permease TnaB; Provisional; Region: PRK09664
866768013530	aromatic amino acid transport protein; Region: araaP; TIGR00837
866768013531	tryptophanase, leader peptide-associated; Region: tnaA_trp_ase; TIGR02617
866768013532	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
866768013533	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
866768013534	catalytic residue [active]
866768013535	Tryptophanese operon leader peptide; Region: Tna_leader; pfam08053
866768013536	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
866768013537	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
866768013538	trmE is a tRNA modification GTPase; Region: trmE; cd04164
866768013539	G1 box; other site
866768013540	GTP/Mg2+ binding site [chemical binding]; other site
866768013541	Switch I region; other site
866768013542	G2 box; other site
866768013543	Switch II region; other site
866768013544	G3 box; other site
866768013545	G4 box; other site
866768013546	G5 box; other site
866768013547	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
866768013548	membrane protein insertase; Provisional; Region: PRK01318
866768013549	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
866768013550	hypothetical protein; Validated; Region: PRK00041
866768013551	ribonuclease P; Reviewed; Region: rnpA; PRK01732
866768013552	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399