-- dump date 20140619_091606 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_002381232.1 218547441 7122062 58..123 1 NC_011740.1 involved in threonine biosynthesis; controls the expression of the thrLABC operon; thr operon leader peptide 123 thrL 7122062 thrL Escherichia fergusonii ATCC 35469 thr operon leader peptide YP_002381232.1 58 D 585054 CDS YP_002381233.1 218547442 7122129 205..2667 1 NC_011740.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 2667 thrA 7122129 thrA Escherichia fergusonii ATCC 35469 bifunctional aspartokinase I/homoserine dehydrogenase I YP_002381233.1 205 D 585054 CDS YP_002381234.1 218547443 7122126 2669..3598 1 NC_011740.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 3598 thrB 7122126 thrB Escherichia fergusonii ATCC 35469 homoserine kinase YP_002381234.1 2669 D 585054 CDS YP_002381235.1 218547444 7122127 3602..4888 1 NC_011740.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 4888 thrC 7122127 thrC Escherichia fergusonii ATCC 35469 threonine synthase YP_002381235.1 3602 D 585054 CDS YP_002381236.1 218547445 7122128 5101..5400 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5400 yaaX 7122128 yaaX Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381236.1 5101 D 585054 CDS YP_002381237.1 218547446 7123473 complement(5437..6210) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 6210 yaaA 7123473 yaaA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381237.1 5437 R 585054 CDS YP_002381238.1 218547447 7122392 complement(6280..7827) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; amino acid sodium/proton transporter 7827 yaaJ 7122392 yaaJ Escherichia fergusonii ATCC 35469 amino acid sodium/proton transporter YP_002381238.1 6280 R 585054 CDS YP_002381239.1 218547448 7124031 7987..8940 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8332529, 92334977, 11298760, 7592346, 8805555, 9007983, 9298646; Product type e : enzyme; transaldolase B 8940 talB 7124031 talB Escherichia fergusonii ATCC 35469 transaldolase B YP_002381239.1 7987 D 585054 CDS YP_002381240.1 218547449 7123405 9055..9642 1 NC_011740.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 9642 mogA 7123405 mogA Escherichia fergusonii ATCC 35469 molybdenum cofactor biosynthesis protein MogA YP_002381240.1 9055 D 585054 CDS YP_002381241.1 218547450 7120955 complement(9676..10242) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 10242 yaaH 7120955 yaaH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381241.1 9676 R 585054 CDS YP_002381242.1 218547451 7124030 10750..12666 1 NC_011740.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 12666 dnaK 7124030 dnaK Escherichia fergusonii ATCC 35469 molecular chaperone DnaK YP_002381242.1 10750 D 585054 CDS YP_002381243.1 218547452 7123988 12755..13885 1 NC_011740.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 13885 dnaJ 7123988 dnaJ Escherichia fergusonii ATCC 35469 chaperone protein DnaJ YP_002381243.1 12755 D 585054 CDS YP_002381244.1 218547453 7124124 complement(13989..14198) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90136075, 92048480, 92048481, 99291074; Product type r : regulator; regulatory protein for HokC, overlaps CDS of hokC 14198 mokC 7124124 mokC Escherichia fergusonii ATCC 35469 regulatory protein for HokC, overlaps CDS of hokC YP_002381244.1 13989 R 585054 CDS YP_002381245.1 218547454 7121799 14682..15848 1 NC_011740.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 15848 nhaA 7121799 nhaA Escherichia fergusonii ATCC 35469 pH-dependent sodium/proton antiporter YP_002381245.1 14682 D 585054 CDS YP_002381246.1 218547455 7120690 15886..16815 1 NC_011740.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC; transcriptional activator NhaR 16815 nhaR 7120690 nhaR Escherichia fergusonii ATCC 35469 transcriptional activator NhaR YP_002381246.1 15886 D 585054 CDS YP_002381247.1 218547456 7120692 complement(16911..17174) 1 NC_011740.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 17174 rpsT 7120692 rpsT Escherichia fergusonii ATCC 35469 30S ribosomal protein S20 YP_002381247.1 16911 R 585054 CDS YP_002381248.1 218547457 7123815 17277..17495 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 17495 yaaY 7123815 yaaY Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381248.1 17277 D 585054 CDS YP_002381249.1 218547458 7122394 17503..18444 1 NC_011740.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 18444 ribF 7122394 ribF Escherichia fergusonii ATCC 35469 bifunctional riboflavin kinase/FMN adenylyltransferase YP_002381249.1 17503 D 585054 CDS YP_002381250.1 218547459 7121409 18487..21303 1 NC_011740.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 21303 ileS 7121409 ileS Escherichia fergusonii ATCC 35469 isoleucyl-tRNA synthetase YP_002381250.1 18487 D 585054 CDS YP_002381251.1 218547460 7123210 21303..21797 1 NC_011740.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 21797 lspA 7123210 lspA Escherichia fergusonii ATCC 35469 lipoprotein signal peptidase YP_002381251.1 21303 D 585054 CDS YP_002381252.1 218547461 7123828 21905..22354 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 97332650, 2011499; Product type e : enzyme; FKBP-type peptidyl-prolyl cis-trans isomerase 22354 fkpB 7123828 fkpB Escherichia fergusonii ATCC 35469 FKBP-type peptidyl-prolyl cis-trans isomerase YP_002381252.1 21905 D 585054 CDS YP_002381253.1 218547462 7122966 22356..23306 1 NC_011740.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 23306 ispH 7122966 ispH Escherichia fergusonii ATCC 35469 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_002381253.1 22356 D 585054 CDS YP_002381254.1 218547463 7120795 23372..24286 1 NC_011740.1 catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides; ribonucleoside hydrolase RihC 24286 rihC 7120795 rihC Escherichia fergusonii ATCC 35469 ribonucleoside hydrolase RihC YP_002381254.1 23372 D 585054 CDS YP_002381255.1 218547464 7121411 24304..24669 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 24669 7121411 EFER_0024 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381255.1 24304 D 585054 CDS YP_002381256.1 218547465 7123748 complement(24715..25398) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type r : regulator; DNA-binding response regulator in two-component regulatory system with citA 25398 citB 7123748 citB Escherichia fergusonii ATCC 35469 DNA-binding response regulator in two-component regulatory system with citA YP_002381256.1 24715 R 585054 CDS YP_002381257.1 218547466 7120895 complement(25391..27019) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type r : regulator; sensory histidine kinase in two-component regulatory system with citB 27019 citA 7120895 citA Escherichia fergusonii ATCC 35469 sensory histidine kinase in two-component regulatory system with citB YP_002381257.1 25391 R 585054 CDS YP_002381258.1 218547467 7123238 complement(27162..28463) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; Oxalacetate decarboxylase subunit beta 28463 oadB 7123238 oadB Escherichia fergusonii ATCC 35469 Oxalacetate decarboxylase subunit beta YP_002381258.1 27162 R 585054 CDS YP_002381259.1 218547468 7119688 complement(28476..30257) 1 NC_011740.1 catalyzes the formation of pyruvate from oxaloacetate; oxaloacetate decarboxylase 30257 oadA 7119688 oadA Escherichia fergusonii ATCC 35469 oxaloacetate decarboxylase YP_002381259.1 28476 R 585054 CDS YP_002381260.1 218547469 7119687 complement(30273..30521) 1 NC_011740.1 catalyzes the decarboxylation of oxaloacetate to form pyruvate and carbon dioxide; oxaloacetate decarboxylase subunit gamma 30521 oadG 7119687 oadG Escherichia fergusonii ATCC 35469 oxaloacetate decarboxylase subunit gamma YP_002381260.1 30273 R 585054 CDS YP_002381261.1 218547470 7123032 complement(30672..32012) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1374406, 1577734, 8810332; Product type t : transporter; Citrate-sodium symporter 32012 citP 7123032 citP Escherichia fergusonii ATCC 35469 Citrate-sodium symporter YP_002381261.1 30672 R 585054 CDS YP_002381262.1 218547471 7120899 32272..33282 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; citrate lyase synthetase 33282 citC 7120899 citC Escherichia fergusonii ATCC 35469 citrate lyase synthetase YP_002381262.1 32272 D 585054 CDS YP_002381263.1 218547472 7120896 33312..33605 1 NC_011740.1 acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma 33605 citD 7120896 citD Escherichia fergusonii ATCC 35469 citrate lyase subunit gamma YP_002381263.1 33312 D 585054 CDS YP_002381264.1 218547473 7120897 33527..34471 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; citrate lyase, citryl-ACP lyase subunit beta 34471 citE 7120897 citE Escherichia fergusonii ATCC 35469 citrate lyase, citryl-ACP lyase subunit beta YP_002381264.1 33527 D 585054 CDS YP_002381265.1 218547474 7120898 34484..36004 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; citrate lyase, citrate-ACP transferase subunit alpha 36004 citF 7120898 citF Escherichia fergusonii ATCC 35469 citrate lyase, citrate-ACP transferase subunit alpha YP_002381265.1 34484 D 585054 CDS YP_002381266.1 218547475 7123239 36004..36555 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; apo-citrate lyase phosphoribosyl-dephospho-CoA transferase 36555 citX 7123239 citX Escherichia fergusonii ATCC 35469 apo-citrate lyase phosphoribosyl-dephospho-CoA transferase YP_002381266.1 36004 D 585054 CDS YP_002381267.1 218547476 7120900 36533..37444 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; triphosphoribosyl-dephospho-CoA transferase 37444 citG 7120900 citG Escherichia fergusonii ATCC 35469 triphosphoribosyl-dephospho-CoA transferase YP_002381267.1 36533 D 585054 CDS YP_002381268.1 218547477 7123770 37603..38424 1 NC_011740.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 38424 dapB 7123770 dapB Escherichia fergusonii ATCC 35469 dihydrodipicolinate reductase YP_002381268.1 37603 D 585054 CDS YP_002381269.1 218547478 7123545 complement(38450..38761) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 38761 7123545 EFER_0039 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381269.1 38450 R 585054 CDS YP_002381270.1 218547479 7120761 38879..40027 1 NC_011740.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 40027 carA 7120761 carA Escherichia fergusonii ATCC 35469 carbamoyl phosphate synthase small subunit YP_002381270.1 38879 D 585054 CDS YP_002381271.1 218547480 7120858 40045..43266 1 NC_011740.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 43266 carB 7120858 carB Escherichia fergusonii ATCC 35469 carbamoyl phosphate synthase large subunit YP_002381271.1 40045 D 585054 CDS YP_002381272.1 218547481 7123232 43527..43922 1 NC_011740.1 regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons; DNA-binding transcriptional activator CaiF 43922 caiF 7123232 caiF Escherichia fergusonii ATCC 35469 DNA-binding transcriptional activator CaiF YP_002381272.1 43527 D 585054 CDS YP_002381273.1 218547482 7120855 complement(44008..44598) 1 NC_011740.1 involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities; carnitine operon protein CaiE 44598 caiE 7120855 caiE Escherichia fergusonii ATCC 35469 carnitine operon protein CaiE YP_002381273.1 44008 R 585054 CDS YP_002381274.1 218547483 7120854 complement(44604..45446) 1 NC_011740.1 catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA; carnitinyl-CoA dehydratase 45446 caiD 7120854 caiD Escherichia fergusonii ATCC 35469 carnitinyl-CoA dehydratase YP_002381274.1 44604 R 585054 CDS YP_002381275.1 218547484 7120853 complement(45499..47067) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15731894, 97189569, 7815937; Product type e : enzyme; crotonobetaine/carnitine-CoA ligase 47067 caiC 7120853 caiC Escherichia fergusonii ATCC 35469 crotonobetaine/carnitine-CoA ligase YP_002381275.1 45499 R 585054 CDS YP_002381276.1 218547485 7123764 complement(47125..48342) 1 NC_011740.1 catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine; crotonobetainyl-CoA:carnitine CoA-transferase 48342 caiB 7123764 caiB Escherichia fergusonii ATCC 35469 crotonobetainyl-CoA:carnitine CoA-transferase YP_002381276.1 47125 R 585054 CDS YP_002381277.1 218547486 7120852 complement(48413..49555) 1 NC_011740.1 catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA; crotonobetainyl-CoA dehydrogenase 49555 caiA 7120852 caiA Escherichia fergusonii ATCC 35469 crotonobetainyl-CoA dehydrogenase YP_002381277.1 48413 R 585054 CDS YP_002381278.1 218547487 7122178 complement(49586..51100) 1 NC_011740.1 catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism; L-carnitine/gamma-butyrobetaine antiporter 51100 caiT 7122178 caiT Escherichia fergusonii ATCC 35469 L-carnitine/gamma-butyrobetaine antiporter YP_002381278.1 49586 R 585054 CDS YP_002381279.1 218547488 7120856 51573..52343 1 NC_011740.1 required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase; electron transfer flavoprotein FixA 52343 fixA 7120856 fixA Escherichia fergusonii ATCC 35469 electron transfer flavoprotein FixA YP_002381279.1 51573 D 585054 CDS YP_002381280.1 218547489 7123630 52358..53299 1 NC_011740.1 involved in electron transfer during carnitine metabolism; electron transfer flavoprotein FixB 53299 fixB 7123630 fixB Escherichia fergusonii ATCC 35469 electron transfer flavoprotein FixB YP_002381280.1 52358 D 585054 CDS YP_002381281.1 218547490 7120020 53350..54636 1 NC_011740.1 FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction; oxidoreductase FixC 54636 fixC 7120020 fixC Escherichia fergusonii ATCC 35469 oxidoreductase FixC YP_002381281.1 53350 D 585054 CDS YP_002381282.1 218547491 7120021 54633..54920 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96066354, 12081978; Product type pc : carrier; 4Fe-4S ferredoxin 54920 fixX 7120021 fixX Escherichia fergusonii ATCC 35469 4Fe-4S ferredoxin YP_002381282.1 54633 D 585054 CDS YP_002381283.1 218547492 7120022 54979..56310 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter 56310 yaaU 7120022 yaaU Escherichia fergusonii ATCC 35469 transporter YP_002381283.1 54979 D 585054 CDS YP_002381284.1 218547493 7122393 56418..56948 1 NC_011740.1 Required for full activity of KefC, a potassium-proton antiporter; glutathione-regulated potassium-efflux system ancillary protein KefF 56948 kefF 7122393 kefF Escherichia fergusonii ATCC 35469 glutathione-regulated potassium-efflux system ancillary protein KefF YP_002381284.1 56418 D 585054 CDS YP_002381285.1 218547494 7123759 56941..58803 1 NC_011740.1 transport system that facilitates potassium-efflux; glutathione-regulated potassium-efflux system protein KefC 58803 kefC 7123759 kefC Escherichia fergusonii ATCC 35469 glutathione-regulated potassium-efflux system protein KefC YP_002381285.1 56941 D 585054 CDS YP_002381286.1 218547495 7120813 58996..59475 1 NC_011740.1 catalyzes the reduction of dihydrofolate to tetrahydrofolate; dihydrofolate reductase 59475 folA 7120813 folA Escherichia fergusonii ATCC 35469 dihydrofolate reductase YP_002381286.1 58996 D 585054 CDS YP_002381287.1 218547496 7123001 59496..59675 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; antitoxin of gyrase inhibiting toxin-antitoxin system 59675 7123001 EFER_0057 Escherichia fergusonii ATCC 35469 antitoxin of gyrase inhibiting toxin-antitoxin system YP_002381287.1 59496 D 585054 CDS YP_002381288.1 218547497 7120762 complement(59792..60241) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 60241 7120762 EFER_0058 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381288.1 59792 R 585054 CDS YP_002381289.1 218547498 7123749 complement(60277..60876) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 60876 7123749 EFER_0059 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381289.1 60277 R 585054 CDS YP_002381290.1 218547499 7120763 complement(60901..61749) 1 NC_011740.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 61749 apaH 7120763 apaH Escherichia fergusonii ATCC 35469 diadenosine tetraphosphatase YP_002381290.1 60901 R 585054 CDS YP_002381291.1 218547500 7123713 complement(61756..62133) 1 NC_011740.1 protein associated with Co2+ and Mg2+ efflux; ApaG protein 62133 apaG 7123713 apaG Escherichia fergusonii ATCC 35469 ApaG protein YP_002381291.1 61756 R 585054 CDS YP_002381292.1 218547501 7120521 complement(62136..62957) 1 NC_011740.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 62957 ksgA 7120521 ksgA Escherichia fergusonii ATCC 35469 dimethyladenosine transferase YP_002381292.1 62136 R 585054 CDS YP_002381293.1 218547502 7120816 complement(62954..63943) 1 NC_011740.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 63943 pdxA 7120816 pdxA Escherichia fergusonii ATCC 35469 4-hydroxythreonine-4-phosphate dehydrogenase YP_002381293.1 62954 R 585054 CDS YP_002381294.1 218547503 7122571 complement(63943..65229) 1 NC_011740.1 Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB; peptidyl-prolyl cis-trans isomerase SurA 65229 surA 7122571 surA Escherichia fergusonii ATCC 35469 peptidyl-prolyl cis-trans isomerase SurA YP_002381294.1 63943 R 585054 CDS YP_002381295.1 218547504 7121967 complement(65283..67634) 1 NC_011740.1 determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein 67634 imp 7121967 imp Escherichia fergusonii ATCC 35469 organic solvent tolerance protein YP_002381295.1 65283 R 585054 CDS YP_002381296.1 218547505 7120736 67889..68704 1 NC_011740.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 68704 djlA 7120736 djlA Escherichia fergusonii ATCC 35469 Dna-J like membrane chaperone protein YP_002381296.1 67889 D 585054 CDS YP_002381297.1 218547506 7122901 complement(68775..69434) 1 NC_011740.1 catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs; 23S rRNA/tRNA pseudouridine synthase A 69434 rluA 7122901 rluA Escherichia fergusonii ATCC 35469 23S rRNA/tRNA pseudouridine synthase A YP_002381297.1 68775 R 585054 CDS YP_002381298.1 218547507 7123866 complement(69446..72352) 1 NC_011740.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA 72352 hepA 7123866 hepA Escherichia fergusonii ATCC 35469 ATP-dependent helicase HepA YP_002381298.1 69446 R 585054 CDS YP_002381299.1 218547508 7122187 complement(72516..74867) 1 NC_011740.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; DNA polymerase II 74867 polB 7122187 polB Escherichia fergusonii ATCC 35469 DNA polymerase II YP_002381299.1 72516 R 585054 CDS YP_002381300.1 218547509 7120098 complement(74942..75637) 1 NC_011740.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 75637 araD 7120098 araD Escherichia fergusonii ATCC 35469 L-ribulose-5-phosphate 4-epimerase YP_002381300.1 74942 R 585054 CDS YP_002381301.1 218547510 7120529 complement(75740..77242) 1 NC_011740.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase 77242 araA 7120529 araA Escherichia fergusonii ATCC 35469 L-arabinose isomerase YP_002381301.1 75740 R 585054 CDS YP_002381302.1 218547511 7120527 complement(77253..78953) 1 NC_011740.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase 78953 araB 7120527 araB Escherichia fergusonii ATCC 35469 ribulokinase YP_002381302.1 77253 R 585054 CDS YP_002381303.1 218547512 7120528 79291..80136 1 NC_011740.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose; DNA-binding transcriptional regulator AraC 80136 araC 7120528 araC Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator AraC YP_002381303.1 79291 D 585054 CDS YP_002381304.1 218547513 7123175 80358..81590 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; sugar metabolism transcriptional regulator 81590 7123175 EFER_0074 Escherichia fergusonii ATCC 35469 sugar metabolism transcriptional regulator YP_002381304.1 80358 D 585054 CDS YP_002381305.1 218547514 7120764 81616..82539 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; dihydrodipicolinate synthetase 82539 7120764 EFER_0075 Escherichia fergusonii ATCC 35469 dihydrodipicolinate synthetase YP_002381305.1 81616 D 585054 CDS YP_002381306.1 218547515 7120765 82594..83547 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; periplasmic binding protein 83547 7120765 EFER_0076 Escherichia fergusonii ATCC 35469 periplasmic binding protein YP_002381306.1 82594 D 585054 CDS YP_002381307.1 218547516 7123217 83560..84033 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 84033 7123217 EFER_0077 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381307.1 83560 D 585054 CDS YP_002381308.1 218547517 7120766 84043..85530 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 85530 7120766 EFER_0078 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381308.1 84043 D 585054 CDS YP_002381309.1 218547518 7120767 85714..86478 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 86478 yabI 7120767 yabI Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381309.1 85714 D 585054 CDS YP_002381310.1 218547519 7122395 complement(86559..87257) 1 NC_011740.1 with TbpA and ThiP is part of the thiamine and TPP transport system; thiamine transporter ATP-binding subunit 87257 thiQ 7122395 thiQ Escherichia fergusonii ATCC 35469 thiamine transporter ATP-binding subunit YP_002381310.1 86559 R 585054 CDS YP_002381311.1 218547520 7121998 complement(87241..88851) 1 NC_011740.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein 88851 thiP 7121998 thiP Escherichia fergusonii ATCC 35469 thiamine transporter membrane protein YP_002381311.1 87241 R 585054 CDS YP_002381312.1 218547521 7121997 complement(88827..89810) 1 NC_011740.1 part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit 89810 tbpA 7121997 tbpA Escherichia fergusonii ATCC 35469 thiamine transporter substrate binding subunit YP_002381312.1 88827 R 585054 CDS YP_002381313.1 218547522 7121982 complement(89974..91629) 1 NC_011740.1 activates sgrS under glucose-phosphate stress conditions; transcriptional regulator SgrR 91629 sgrR 7121982 sgrR Escherichia fergusonii ATCC 35469 transcriptional regulator SgrR YP_002381313.1 89974 R 585054 CDS YP_002381314.1 218547523 7121780 91949..93127 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10438463, 10209755; Product type t : transporter; broad specificity sugar efflux system 93127 setA 7121780 setA Escherichia fergusonii ATCC 35469 broad specificity sugar efflux system YP_002381314.1 91949 D 585054 CDS YP_002381315.1 218547524 7120768 94730..95626 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type r : regulator; LysR family transcriptional regulator 95626 7120768 EFER_0088 Escherichia fergusonii ATCC 35469 LysR family transcriptional regulator YP_002381315.1 94730 D 585054 CDS YP_002381316.1 218547525 7120769 complement(95663..96430) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; 3-dehydroquinate dehydratase 96430 aroD 7120769 aroD Escherichia fergusonii ATCC 35469 3-dehydroquinate dehydratase YP_002381316.1 95663 R 585054 CDS YP_002381317.1 218547526 7120546 complement(96448..97740) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; MFS superfamily transporter 97740 7120546 EFER_0090 Escherichia fergusonii ATCC 35469 MFS superfamily transporter YP_002381317.1 96448 R 585054 CDS YP_002381318.1 218547527 7120770 complement(97670..98533) 1 NC_011740.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 98533 aroE 7120770 aroE Escherichia fergusonii ATCC 35469 shikimate 5-dehydrogenase YP_002381318.1 97670 R 585054 CDS YP_002381319.1 218547528 7120771 complement(98552..100564) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; NADH:flavin oxidoreductase 100564 7120771 EFER_0092 Escherichia fergusonii ATCC 35469 NADH:flavin oxidoreductase YP_002381319.1 98552 R 585054 CDS YP_002381320.1 218547529 7123750 complement(100830..101435) 1 NC_011740.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 101435 leuD 7123750 leuD Escherichia fergusonii ATCC 35469 isopropylmalate isomerase small subunit YP_002381320.1 100830 R 585054 CDS YP_002381321.1 218547530 7120826 complement(101446..102846) 1 NC_011740.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 102846 leuC 7120826 leuC Escherichia fergusonii ATCC 35469 isopropylmalate isomerase large subunit YP_002381321.1 101446 R 585054 CDS YP_002381322.1 218547531 7120825 complement(102849..103940) 1 NC_011740.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 103940 leuB 7120825 leuB Escherichia fergusonii ATCC 35469 3-isopropylmalate dehydrogenase YP_002381322.1 102849 R 585054 CDS YP_002381323.1 218547532 7120824 complement(103940..105511) 1 NC_011740.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 105511 leuA 7120824 leuA Escherichia fergusonii ATCC 35469 2-isopropylmalate synthase YP_002381323.1 103940 R 585054 CDS YP_002381324.1 218547533 7123228 complement(105601..105687) 1 NC_011740.1 involved in attenuation control of the leuABCD operon in leucine biosynthesis; leu operon leader peptide 105687 leuL 7123228 leuL Escherichia fergusonii ATCC 35469 leu operon leader peptide YP_002381324.1 105601 R 585054 CDS YP_002381325.1 218547534 7120827 106327..107289 1 NC_011740.1 activator for leuABCD operon; member of LysR family of transcriptional activators; leucine transcriptional activator 107289 leuO 7120827 leuO Escherichia fergusonii ATCC 35469 leucine transcriptional activator YP_002381325.1 106327 D 585054 CDS YP_002381326.1 218547535 7123229 107606..109330 1 NC_011740.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; acetolactate synthase 3 catalytic subunit 109330 ilvI 7123229 ilvI Escherichia fergusonii ATCC 35469 acetolactate synthase 3 catalytic subunit YP_002381326.1 107606 D 585054 CDS YP_002381327.1 218547536 7120732 109333..109824 1 NC_011740.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 109824 ilvH 7120732 ilvH Escherichia fergusonii ATCC 35469 acetolactate synthase 3 regulatory subunit YP_002381327.1 109333 D 585054 CDS YP_002381328.1 218547537 7123743 110005..111009 1 NC_011740.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism; DNA-binding transcriptional regulator FruR 111009 fruR 7123743 fruR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator FruR YP_002381328.1 110005 D 585054 CDS YP_002381329.1 218547538 7123572 111603..112061 1 NC_011740.1 MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 112061 mraZ 7123572 mraZ Escherichia fergusonii ATCC 35469 cell division protein MraZ YP_002381329.1 111603 D 585054 CDS YP_002381330.1 218547539 7120964 112063..113004 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20042184, 10493123, 2187182, 6350821; Product type e : enzyme; S-adenosyl-methyltransferase MraW 113004 mraW 7120964 mraW Escherichia fergusonii ATCC 35469 S-adenosyl-methyltransferase MraW YP_002381330.1 112063 D 585054 CDS YP_002381331.1 218547540 7120963 113001..113366 1 NC_011740.1 membrane bound cell division protein at septum containing leucine zipper motif; cell division protein FtsL 113366 ftsL 7120963 ftsL Escherichia fergusonii ATCC 35469 cell division protein FtsL YP_002381331.1 113001 D 585054 CDS YP_002381332.1 218547541 7120149 113382..115148 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91072213, 92202178, 94095121, 9603865, 9614966, 1332942, 1447153, 2198024, 2677607, 2681146, 3049550, 3911028, 6350821; Product type e : enzyme; septal peptidoglycan synthesis transpeptidase 115148 ftsI 7120149 ftsI Escherichia fergusonii ATCC 35469 septal peptidoglycan synthesis transpeptidase YP_002381332.1 113382 D 585054 CDS YP_002381333.1 218547542 7123112 115135..116622 1 NC_011740.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 116622 murE 7123112 murE Escherichia fergusonii ATCC 35469 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_002381333.1 115135 D 585054 CDS YP_002381334.1 218547543 7120646 116619..117977 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88273095, 90248455, 91310568, 97128642, 11090285, 2668880, 9166795; Product type e : enzyme; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 117977 murF 7120646 murF Escherichia fergusonii ATCC 35469 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase YP_002381334.1 116619 D 585054 CDS YP_002381335.1 218547544 7120647 117971..119053 1 NC_011740.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 119053 mraY 7120647 mraY Escherichia fergusonii ATCC 35469 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_002381335.1 117971 D 585054 CDS YP_002381336.1 218547545 7123783 119056..120372 1 NC_011740.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 120372 murD 7123783 murD Escherichia fergusonii ATCC 35469 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_002381336.1 119056 D 585054 CDS YP_002381337.1 218547546 7123196 120372..121616 1 NC_011740.1 integral membrane protein involved in stabilizing FstZ ring during cell division; cell division protein FtsW 121616 ftsW 7123196 ftsW Escherichia fergusonii ATCC 35469 cell division protein FtsW YP_002381337.1 120372 D 585054 CDS YP_002381338.1 218547547 7123652 121613..122680 1 NC_011740.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 122680 murG 7123652 murG Escherichia fergusonii ATCC 35469 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase YP_002381338.1 121613 D 585054 CDS YP_002381339.1 218547548 7120648 122734..124209 1 NC_011740.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 124209 murC 7120648 murC Escherichia fergusonii ATCC 35469 UDP-N-acetylmuramate--L-alanine ligase YP_002381339.1 122734 D 585054 CDS YP_002381340.1 218547549 7123195 124202..125122 1 NC_011740.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 125122 ddl 7123195 ddl Escherichia fergusonii ATCC 35469 D-alanine--D-alanine ligase YP_002381340.1 124202 D 585054 CDS YP_002381341.1 218547550 7123547 125124..125954 1 NC_011740.1 involved in septum formation; cell division protein FtsQ 125954 ftsQ 7123547 ftsQ Escherichia fergusonii ATCC 35469 cell division protein FtsQ YP_002381341.1 125124 D 585054 CDS YP_002381342.1 218547551 7123651 125951..127213 1 NC_011740.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane; cell division protein FtsA 127213 ftsA 7123651 ftsA Escherichia fergusonii ATCC 35469 cell division protein FtsA YP_002381342.1 125951 D 585054 CDS YP_002381343.1 218547552 7120146 127275..128426 1 NC_011740.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 128426 ftsZ 7120146 ftsZ Escherichia fergusonii ATCC 35469 cell division protein FtsZ YP_002381343.1 127275 D 585054 CDS YP_002381344.1 218547553 7120152 128527..129444 1 NC_011740.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 129444 lpxC 7120152 lpxC Escherichia fergusonii ATCC 35469 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_002381344.1 128527 D 585054 CDS YP_002381345.1 218547554 7121201 129625..130182 1 NC_011740.1 secM translational pause allows for the initiation of secA translation; SecA regulator SecM 130182 secM 7121201 secM Escherichia fergusonii ATCC 35469 SecA regulator SecM YP_002381345.1 129625 D 585054 CDS YP_002381346.1 218547555 7121764 130244..132949 1 NC_011740.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 132949 secA 7121764 secA Escherichia fergusonii ATCC 35469 preprotein translocase subunit SecA YP_002381346.1 130244 D 585054 CDS YP_002381347.1 218547556 7121760 133012..133410 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10218109, 89264540, 90136514, 91225007, 97444511, 1309939, 2841285, 3033442, 3288626, 7578113, 9063868; Product type e : enzyme; nucleoside triphosphate pyrophosphohydrolase 133410 mutT 7121760 mutT Escherichia fergusonii ATCC 35469 nucleoside triphosphate pyrophosphohydrolase YP_002381347.1 133012 D 585054 CDS YP_002381348.1 218547557 7123729 complement(133506..133700) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12211008, 3033442; zinc-binding protein 133700 yacG 7123729 yacG Escherichia fergusonii ATCC 35469 zinc-binding protein YP_002381348.1 133506 R 585054 CDS YP_002381349.1 218547558 7123474 complement(133710..134453) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 134453 yacF 7123474 yacF Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381349.1 133710 R 585054 CDS YP_002381350.1 218547559 7122397 complement(134453..135073) 1 NC_011740.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 135073 coaE 7122397 coaE Escherichia fergusonii ATCC 35469 dephospho-CoA kinase YP_002381350.1 134453 R 585054 CDS YP_002381351.1 218547560 7120910 135299..136342 1 NC_011740.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; guanosine 5'-monophosphate oxidoreductase 136342 guaC 7120910 guaC Escherichia fergusonii ATCC 35469 guanosine 5'-monophosphate oxidoreductase YP_002381351.1 135299 D 585054 CDS YP_002381352.1 218547561 7120624 complement(136377..137612) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 96099298, 2904262, 7959070; Product type s : structure; type IV pilin biogenesis protein 137612 hofC 7120624 hofC Escherichia fergusonii ATCC 35469 type IV pilin biogenesis protein YP_002381352.1 136377 R 585054 CDS YP_002381353.1 218547562 7122206 complement(137569..138954) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 138954 hofB 7122206 hofB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381353.1 137569 R 585054 CDS YP_002381354.1 218547563 7124000 complement(138964..139401) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 20100782, 20271862, 96099298, 7959070; Product type ps : structure; major pilin subunit 139401 ppdD 7124000 ppdD Escherichia fergusonii ATCC 35469 major pilin subunit YP_002381354.1 138964 R 585054 CDS YP_002381355.1 218547564 7120109 complement(139615..140508) 1 NC_011740.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; quinolinate phosphoribosyltransferase 140508 nadC 7120109 nadC Escherichia fergusonii ATCC 35469 quinolinate phosphoribosyltransferase YP_002381355.1 139615 R 585054 CDS YP_002381356.1 218547565 7120659 140596..141147 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90113890, 95047240, 2607970, 7959070; Product type e : enzyme; N-acetyl-anhydromuranmyl-L-alanine amidase 141147 ampD 7120659 ampD Escherichia fergusonii ATCC 35469 N-acetyl-anhydromuranmyl-L-alanine amidase YP_002381356.1 140596 D 585054 CDS YP_002381357.1 218547566 7120512 141144..141998 1 NC_011740.1 involved in regulation of beta-lactamase; signaling protein; regulatory protein AmpE 141998 ampE 7120512 ampE Escherichia fergusonii ATCC 35469 regulatory protein AmpE YP_002381357.1 141144 D 585054 CDS YP_002381358.1 218547567 7120513 complement(142038..143411) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1104763, 90174991, 9150230; Product type t : transporter; aromatic amino acid transporter 143411 aroP 7120513 aroP Escherichia fergusonii ATCC 35469 aromatic amino acid transporter YP_002381358.1 142038 R 585054 CDS YP_002381359.1 218547568 7120553 144001..144765 1 NC_011740.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; transcriptional regulator PdhR 144765 pdhR 7120553 pdhR Escherichia fergusonii ATCC 35469 transcriptional regulator PdhR YP_002381359.1 144001 D 585054 CDS YP_002381360.1 218547569 7122149 complement(144762..144944) 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 144944 7122149 EFER_0134 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381360.1 144762 R 585054 CDS YP_002381361.1 218547570 7120772 144926..147589 1 NC_011740.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 147589 aceE 7120772 aceE Escherichia fergusonii ATCC 35469 pyruvate dehydrogenase subunit E1 YP_002381361.1 144926 D 585054 CDS YP_002381362.1 218547571 7122257 147604..149496 1 NC_011740.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase 149496 aceF 7122257 aceF Escherichia fergusonii ATCC 35469 dihydrolipoamide acetyltransferase YP_002381362.1 147604 D 585054 CDS YP_002381363.1 218547572 7122258 149704..151128 1 NC_011740.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 151128 lpd 7122258 lpd Escherichia fergusonii ATCC 35469 dihydrolipoamide dehydrogenase YP_002381363.1 149704 D 585054 CDS YP_002381364.1 218547573 7120849 complement(151199..153055) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 153055 yacH 7120849 yacH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381364.1 151199 R 585054 CDS YP_002381365.1 218547574 7122398 153410..156007 1 NC_011740.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 156007 acnB 7122398 acnB Escherichia fergusonii ATCC 35469 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase YP_002381365.1 153410 D 585054 CDS YP_002381366.1 218547575 7122261 156204..156566 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2666401, 7567469; hypothetical protein 156566 yacL 7122261 yacL Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381366.1 156204 D 585054 CDS YP_002381367.1 218547576 7122399 complement(156604..157398) 1 NC_011740.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase 157398 speD 7122399 speD Escherichia fergusonii ATCC 35469 S-adenosylmethionine decarboxylase YP_002381367.1 156604 R 585054 CDS YP_002381368.1 218547577 7121804 complement(157414..158280) 1 NC_011740.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 158280 speE 7121804 speE Escherichia fergusonii ATCC 35469 spermidine synthase YP_002381368.1 157414 R 585054 CDS YP_002381369.1 218547578 7121805 complement(158386..158904) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2666401; hypothetical protein 158904 yacC 7121805 yacC Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381369.1 158386 R 585054 CDS YP_002381370.1 218547579 7122396 158899..160449 1 NC_011740.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase 160449 cueO 7122396 cueO Escherichia fergusonii ATCC 35469 multicopper oxidase YP_002381370.1 158899 D 585054 CDS YP_002381371.1 218547580 7122826 complement(160496..162886) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10359647, 11604400, 14612441, 91035240, 93123180, 93286127; Product type e : enzyme; glucose dehydrogenase 162886 gcd 7122826 gcd Escherichia fergusonii ATCC 35469 glucose dehydrogenase YP_002381371.1 160496 R 585054 CDS YP_002381372.1 218547581 7120176 163092..163628 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 13808016, 339828, 6787390, 6801015, 12070315; Product type e : enzyme; hypoxanthine phosphoribosyltransferase 163628 hpt 7120176 hpt Escherichia fergusonii ATCC 35469 hypoxanthine phosphoribosyltransferase YP_002381372.1 163092 D 585054 CDS YP_002381373.1 218547582 7122220 complement(163669..164331) 1 NC_011740.1 catalyzes the interconversion of bicarbonate and carbon dioxide; carbonic anhydrase 164331 can 7122220 can Escherichia fergusonii ATCC 35469 carbonic anhydrase YP_002381373.1 163669 R 585054 CDS YP_002381374.1 218547583 7120857 164440..165366 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter ATP-binding protein 165366 yadG 7120857 yadG Escherichia fergusonii ATCC 35469 ABC transporter ATP-binding protein YP_002381374.1 164440 D 585054 CDS YP_002381375.1 218547584 7122402 165363..166133 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10474187; Product type pt : transporter; ABC transporter membrane protein 166133 yadH 7122402 yadH Escherichia fergusonii ATCC 35469 ABC transporter membrane protein YP_002381375.1 165363 D 585054 CDS YP_002381376.1 218547585 7122403 166238..166678 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; PTS system transporter subunit IIA 166678 yadI 7122403 yadI Escherichia fergusonii ATCC 35469 PTS system transporter subunit IIA YP_002381376.1 166238 D 585054 CDS YP_002381377.1 218547586 7122404 166735..167961 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; polysaccharide deacetylase 167961 yadE 7122404 yadE Escherichia fergusonii ATCC 35469 polysaccharide deacetylase YP_002381377.1 166735 D 585054 CDS YP_002381378.1 218547587 7122401 complement(167965..168345) 1 NC_011740.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 168345 panD 7122401 panD Escherichia fergusonii ATCC 35469 aspartate alpha-decarboxylase YP_002381378.1 167965 R 585054 CDS YP_002381379.1 218547588 7123498 168619..169551 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11319082; Product type pe : enzyme; transposase 169551 yadD 7123498 yadD Escherichia fergusonii ATCC 35469 transposase YP_002381379.1 168619 D 585054 CDS YP_002381380.1 218547589 7124033 complement(169917..170768) 1 NC_011740.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 170768 panC 7124033 panC Escherichia fergusonii ATCC 35469 pantoate--beta-alanine ligase YP_002381380.1 169917 R 585054 CDS YP_002381381.1 218547590 7122553 complement(170780..171574) 1 NC_011740.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 171574 panB 7122553 panB Escherichia fergusonii ATCC 35469 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_002381381.1 170780 R 585054 CDS YP_002381382.1 218547591 7122552 complement(171686..172972) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; fimbrial-like adhesin protein 172972 yadC 7122552 yadC Escherichia fergusonii ATCC 35469 fimbrial-like adhesin protein YP_002381382.1 171686 R 585054 CDS YP_002381383.1 218547592 7124032 complement(172997..173593) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; fimbrial-like adhesin protein 173593 7124032 EFER_0158 Escherichia fergusonii ATCC 35469 fimbrial-like adhesin protein YP_002381383.1 172997 R 585054 CDS YP_002381384.1 218547593 7120773 complement(173619..174233) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; fimbrial-like adhesin protein 174233 yadL 7120773 yadL Escherichia fergusonii ATCC 35469 fimbrial-like adhesin protein YP_002381384.1 173619 R 585054 CDS YP_002381385.1 218547594 7124034 complement(174239..174814) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; fimbrial-like adhesin protein 174814 yadM 7124034 yadM Escherichia fergusonii ATCC 35469 fimbrial-like adhesin protein YP_002381385.1 174239 R 585054 CDS YP_002381386.1 218547595 7122405 complement(174830..177427) 1 NC_011740.1 similar to the fimbrial usher protein PapC; outer membrane usher protein 177427 htrE 7122405 htrE Escherichia fergusonii ATCC 35469 outer membrane usher protein YP_002381386.1 174830 R 585054 CDS YP_002381387.1 218547596 7124003 complement(177463..178203) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 93352405, 8102362, 15561151; Product type f : factor; chaperone protein EcpD 178203 ecpD 7124003 ecpD Escherichia fergusonii ATCC 35469 chaperone protein EcpD YP_002381387.1 177463 R 585054 CDS YP_002381388.1 218547597 7122936 complement(178300..178884) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; fimbrial-like adhesin protein 178884 yadN 7122936 yadN Escherichia fergusonii ATCC 35469 fimbrial-like adhesin protein YP_002381388.1 178300 R 585054 CDS YP_002381389.1 218547598 7123475 complement(179239..179718) 1 NC_011740.1 catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 179718 folK 7123475 folK Escherichia fergusonii ATCC 35469 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase YP_002381389.1 179239 R 585054 CDS YP_002381390.1 218547599 7123004 complement(179715..181133) 1 NC_011740.1 Polymerase that creates the 3' poly(A) tail found in some mRNA's; poly(A) polymerase I 181133 pcnB 7123004 pcnB Escherichia fergusonii ATCC 35469 poly(A) polymerase I YP_002381390.1 179715 R 585054 CDS YP_002381391.1 218547600 7122566 complement(181172..182080) 1 NC_011740.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase 182080 yadB 7122566 yadB Escherichia fergusonii ATCC 35469 glutamyl-Q tRNA(Asp) synthetase YP_002381391.1 181172 R 585054 CDS YP_002381392.1 218547601 7122400 complement(182134..182589) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15294157, 90202727, 2013578, 9298646, 9600841; Product type r : regulator; RNA polymerase-binding transcription factor 182589 dksA 7122400 dksA Escherichia fergusonii ATCC 35469 RNA polymerase-binding transcription factor YP_002381392.1 182134 R 585054 CDS YP_002381393.1 218547602 7122906 complement(182768..183472) 1 NC_011740.1 Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A 183472 sfsA 7122906 sfsA Escherichia fergusonii ATCC 35469 sugar fermentation stimulation protein A YP_002381393.1 182768 R 585054 CDS YP_002381394.1 218547603 7121775 complement(183487..184242) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; 2'-5' RNA ligase 184242 ligT 7121775 ligT Escherichia fergusonii ATCC 35469 2'-5' RNA ligase YP_002381394.1 183487 R 585054 CDS YP_002381395.1 218547604 7123760 184091..186520 1 NC_011740.1 similar in sequence to the ATP-dependent RNA helicase HrpA; ATP-dependent RNA helicase HrpB 186520 hrpB 7123760 hrpB Escherichia fergusonii ATCC 35469 ATP-dependent RNA helicase HrpB YP_002381395.1 184091 D 585054 CDS YP_002381396.1 218547605 7122221 186614..189148 1 NC_011740.1 bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell; penicillin-binding protein 1b 189148 mrcB 7122221 mrcB Escherichia fergusonii ATCC 35469 penicillin-binding protein 1b YP_002381396.1 186614 D 585054 CDS YP_002381397.1 218547606 7123249 189368..191557 1 NC_011740.1 involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein; ferrichrome outer membrane transporter 191557 fhuA 7123249 fhuA Escherichia fergusonii ATCC 35469 ferrichrome outer membrane transporter YP_002381397.1 189368 D 585054 CDS YP_002381398.1 218547607 7120012 191608..192405 1 NC_011740.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; iron-hydroxamate transporter ATP-binding subunit 192405 fhuC 7120012 fhuC Escherichia fergusonii ATCC 35469 iron-hydroxamate transporter ATP-binding subunit YP_002381398.1 191608 D 585054 CDS YP_002381399.1 218547608 7120014 192405..193295 1 NC_011740.1 Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores; iron-hydroxamate transporter substrate-binding subunit 193295 fhuD 7120014 fhuD Escherichia fergusonii ATCC 35469 iron-hydroxamate transporter substrate-binding subunit YP_002381399.1 192405 D 585054 CDS YP_002381400.1 218547609 7120015 193292..195274 1 NC_011740.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease subunit 195274 fhuB 7120015 fhuB Escherichia fergusonii ATCC 35469 iron-hydroxamate transporter permease subunit YP_002381400.1 193292 D 585054 CDS YP_002381401.1 218547610 7120013 complement(195309..196589) 1 NC_011740.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 196589 hemL 7120013 hemL Escherichia fergusonii ATCC 35469 glutamate-1-semialdehyde aminotransferase YP_002381401.1 195309 R 585054 CDS YP_002381402.1 218547611 7123995 196814..198235 1 NC_011740.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein 198235 clcA 7123995 clcA Escherichia fergusonii ATCC 35469 chloride channel protein YP_002381402.1 196814 D 585054 CDS YP_002381403.1 218547612 7120901 198317..198661 1 NC_011740.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 198661 yadR 7120901 yadR Escherichia fergusonii ATCC 35469 iron-sulfur cluster insertion protein ErpA YP_002381403.1 198317 D 585054 CDS YP_002381404.1 218547613 7122406 complement(198722..199351) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 199351 7122406 EFER_0180 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381404.1 198722 R 585054 CDS YP_002381405.1 218547614 7120774 complement(199387..200214) 1 NC_011740.1 solute binding component of the vitamin B12 transport system BtuCDF; vitamin B12-transporter protein BtuF 200214 btuF 7120774 btuF Escherichia fergusonii ATCC 35469 vitamin B12-transporter protein BtuF YP_002381405.1 199387 R 585054 CDS YP_002381406.1 218547615 7123360 complement(200180..200878) 1 NC_011740.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 200878 pfs 7123360 pfs Escherichia fergusonii ATCC 35469 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_002381406.1 200180 R 585054 CDS YP_002381407.1 218547616 7124065 200961..202478 1 NC_011740.1 forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase 202478 dgt 7124065 dgt Escherichia fergusonii ATCC 35469 deoxyguanosinetriphosphate triphosphohydrolase YP_002381407.1 200961 D 585054 CDS YP_002381408.1 218547617 7123551 202608..204032 1 NC_011740.1 protease Do; required at high temperature; degrades damaged proteins; serine endoprotease 204032 degP 7123551 degP Escherichia fergusonii ATCC 35469 serine endoprotease YP_002381408.1 202608 D 585054 CDS YP_002381409.1 218547618 7123548 204190..205347 1 NC_011740.1 regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization; carbohydrate diacid transcriptional activator CdaR 205347 cdaR 7123548 cdaR Escherichia fergusonii ATCC 35469 carbohydrate diacid transcriptional activator CdaR YP_002381409.1 204190 D 585054 CDS YP_002381410.1 218547619 7120873 complement(205462..205848) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 205848 yaeH 7120873 yaeH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381410.1 205462 R 585054 CDS YP_002381411.1 218547620 7122409 complement(206006..206821) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; phosphodiesterase YaeI 206821 yaeI 7122409 yaeI Escherichia fergusonii ATCC 35469 phosphodiesterase YaeI YP_002381411.1 206006 R 585054 CDS YP_002381412.1 218547621 7122410 complement(206872..207696) 1 NC_011740.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 207696 dapD 7122410 dapD Escherichia fergusonii ATCC 35469 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_002381412.1 206872 R 585054 CDS YP_002381413.1 218547622 7123546 complement(207727..210399) 1 NC_011740.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase 210399 glnD 7123546 glnD Escherichia fergusonii ATCC 35469 PII uridylyl-transferase YP_002381413.1 207727 R 585054 CDS YP_002381414.1 218547623 7120195 complement(210461..211255) 1 NC_011740.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 211255 map 7120195 map Escherichia fergusonii ATCC 35469 methionine aminopeptidase YP_002381414.1 210461 R 585054 CDS YP_002381415.1 218547624 7123955 211623..212348 1 NC_011740.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 212348 rpsB 7123955 rpsB Escherichia fergusonii ATCC 35469 30S ribosomal protein S2 YP_002381415.1 211623 D 585054 CDS YP_002381416.1 218547625 7121127 212483..213334 1 NC_011740.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 213334 tsf 7121127 tsf Escherichia fergusonii ATCC 35469 elongation factor Ts YP_002381416.1 212483 D 585054 CDS YP_002381417.1 218547626 7122174 213481..214206 1 NC_011740.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 214206 pyrH 7122174 pyrH Escherichia fergusonii ATCC 35469 uridylate kinase YP_002381417.1 213481 D 585054 CDS YP_002381418.1 218547627 7122337 214356..214913 1 NC_011740.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 214913 frr 7122337 frr Escherichia fergusonii ATCC 35469 ribosome recycling factor YP_002381418.1 214356 D 585054 CDS YP_002381419.1 218547628 7123013 215006..216202 1 NC_011740.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 216202 dxr 7123013 dxr Escherichia fergusonii ATCC 35469 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_002381419.1 215006 D 585054 CDS YP_002381420.1 218547629 7123556 216388..217149 1 NC_011740.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 217149 ispU 7123556 ispU Escherichia fergusonii ATCC 35469 undecaprenyl pyrophosphate synthase YP_002381420.1 216388 D 585054 CDS YP_002381421.1 218547630 7120796 217162..218019 1 NC_011740.1 catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; CDP-diglyceride synthase 218019 cdsA 7120796 cdsA Escherichia fergusonii ATCC 35469 CDP-diglyceride synthase YP_002381421.1 217162 D 585054 CDS YP_002381422.1 218547631 7120876 218031..219383 1 NC_011740.1 catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; zinc metallopeptidase RseP 219383 yaeL 7120876 yaeL Escherichia fergusonii ATCC 35469 zinc metallopeptidase RseP YP_002381422.1 218031 D 585054 CDS YP_002381423.1 218547632 7122412 219415..221823 1 NC_011740.1 part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; outer membrane protein assembly factor YaeT 221823 yaeT 7122412 yaeT Escherichia fergusonii ATCC 35469 outer membrane protein assembly factor YaeT YP_002381423.1 219415 D 585054 CDS YP_002381424.1 218547633 7123477 221947..222432 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15101556, 90201355, 97032152, 99386928, 1987124, 2843433, 9298646, 2167239; Product type f : factor; periplasmic chaperone 222432 hlpA 7123477 hlpA Escherichia fergusonii ATCC 35469 periplasmic chaperone YP_002381424.1 221947 D 585054 CDS YP_002381425.1 218547634 7122204 222436..223461 1 NC_011740.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 223461 lpxD 7122204 lpxD Escherichia fergusonii ATCC 35469 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_002381425.1 222436 D 585054 CDS YP_002381426.1 218547635 7121202 223566..224021 1 NC_011740.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 224021 fabZ 7121202 fabZ Escherichia fergusonii ATCC 35469 (3R)-hydroxymyristoyl-ACP dehydratase YP_002381426.1 223566 D 585054 CDS YP_002381427.1 218547636 7123625 224025..224813 1 NC_011740.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 224813 lpxA 7123625 lpxA Escherichia fergusonii ATCC 35469 UDP-N-acetylglucosamine acyltransferase YP_002381427.1 224025 D 585054 CDS YP_002381428.1 218547637 7121199 224813..225961 1 NC_011740.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 225961 lpxB 7121199 lpxB Escherichia fergusonii ATCC 35469 lipid-A-disaccharide synthase YP_002381428.1 224813 D 585054 CDS YP_002381429.1 218547638 7121200 225958..226554 1 NC_011740.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 226554 rnhB 7121200 rnhB Escherichia fergusonii ATCC 35469 ribonuclease HII YP_002381429.1 225958 D 585054 CDS YP_002381430.1 218547639 7121428 226591..230073 1 NC_011740.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 230073 dnaE 7121428 dnaE Escherichia fergusonii ATCC 35469 DNA polymerase III subunit alpha YP_002381430.1 226591 D 585054 CDS YP_002381431.1 218547640 7122910 230086..231045 1 NC_011740.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 231045 accA 7122910 accA Escherichia fergusonii ATCC 35469 acetyl-CoA carboxylase carboxyltransferase subunit alpha YP_002381431.1 230086 D 585054 CDS YP_002381432.1 218547641 7122253 231143..233284 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 97480927, 98195734, 98357244, 9226257, 9723924; Product type e : enzyme; lysine decarboxylase 2 233284 ldcC 7122253 ldcC Escherichia fergusonii ATCC 35469 lysine decarboxylase 2 YP_002381432.1 231143 D 585054 CDS YP_002381433.1 218547642 7120818 233341..233730 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 233730 yaeR 7120818 yaeR Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381433.1 233341 D 585054 CDS YP_002381434.1 218547643 7123476 233795..235093 1 NC_011740.1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase; tRNA(Ile)-lysidine synthetase 235093 tilS 7123476 tilS Escherichia fergusonii ATCC 35469 tRNA(Ile)-lysidine synthetase YP_002381434.1 233795 D 585054 CDS YP_002381435.1 218547644 7123985 complement(235142..235396) 1 NC_011740.1 Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination; Rho-binding antiterminator 235396 rof 7123985 rof Escherichia fergusonii ATCC 35469 Rho-binding antiterminator YP_002381435.1 235142 R 585054 CDS YP_002381436.1 218547645 7121433 complement(235389..235589) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 235589 yaeP 7121433 yaeP Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381436.1 235389 R 585054 CDS YP_002381437.1 218547646 7122413 235755..236300 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 236300 yaeQ 7122413 yaeQ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381437.1 235755 D 585054 CDS YP_002381438.1 218547647 7122414 236297..236719 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; peptidyl-tRNA hydrolase domain-containing protein 236719 yaeJ 7122414 yaeJ Escherichia fergusonii ATCC 35469 peptidyl-tRNA hydrolase domain-containing protein YP_002381438.1 236297 D 585054 CDS YP_002381439.1 218547648 7122411 236733..237443 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11830644, 95362641, 95362642; Product type lp : lipoprotein; lipoprotein 237443 nlpE 7122411 nlpE Escherichia fergusonii ATCC 35469 lipoprotein YP_002381439.1 236733 D 585054 CDS YP_002381440.1 218547649 7119652 complement(237599..238423) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; hypothetical protein 238423 yaeF 7119652 yaeF Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381440.1 237599 R 585054 CDS YP_002381441.1 218547650 7122408 complement(238476..240194) 1 NC_011740.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 240194 proS 7122408 proS Escherichia fergusonii ATCC 35469 prolyl-tRNA synthetase YP_002381441.1 238476 R 585054 CDS YP_002381442.1 218547651 7123110 complement(240305..241012) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 241012 yaeB 7123110 yaeB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381442.1 240305 R 585054 CDS YP_002381443.1 218547652 7122407 complement(241009..241413) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 93094132; Product type pr : regulator; outer membrane lipoprotein 241413 rcsF 7122407 rcsF Escherichia fergusonii ATCC 35469 outer membrane lipoprotein YP_002381443.1 241009 R 585054 CDS YP_002381444.1 218547653 7122355 complement(241531..242346) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12169620, 12218041, 12819857, 1459951; Product type t : transporter; DL-methionine transporter substrate-binding subunit 242346 metQ 7122355 metQ Escherichia fergusonii ATCC 35469 DL-methionine transporter substrate-binding subunit YP_002381444.1 241531 R 585054 CDS YP_002381445.1 218547654 7120925 complement(242386..243039) 1 NC_011740.1 part of the MetNIQ methionine uptake system; DL-methionine transporter permease 243039 metI 7120925 metI Escherichia fergusonii ATCC 35469 DL-methionine transporter permease YP_002381445.1 242386 R 585054 CDS YP_002381446.1 218547655 7120921 complement(243032..244063) 1 NC_011740.1 part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit 244063 metN 7120921 metN Escherichia fergusonii ATCC 35469 DL-methionine transporter ATP-binding subunit YP_002381446.1 243032 R 585054 CDS YP_002381447.1 218547656 7120924 244251..244823 1 NC_011740.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 244823 gmhB 7120924 gmhB Escherichia fergusonii ATCC 35469 D,D-heptose 1,7-bisphosphate phosphatase YP_002381447.1 244251 D 585054 CDS YP_002381448.1 218547657 7120041 250591..251394 1 NC_011740.1 catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; 2,5-diketo-D-gluconate reductase B 251394 dkgB 7120041 dkgB Escherichia fergusonii ATCC 35469 2,5-diketo-D-gluconate reductase B YP_002381448.1 250591 D 585054 CDS YP_002381449.1 218547658 7122905 complement(251391..252305) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator 252305 yafC 7122905 yafC Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YP_002381449.1 251391 R 585054 CDS YP_002381450.1 218547659 7122415 252546..253346 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1663890; hypothetical protein 253346 yafD 7122415 yafD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381450.1 252546 D 585054 CDS YP_002381451.1 218547660 7122416 253424..254194 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; S-adenosyl-L-methionine-dependent methyltransferase 254194 yafE 7122416 yafE Escherichia fergusonii ATCC 35469 S-adenosyl-L-methionine-dependent methyltransferase YP_002381451.1 253424 D 585054 CDS YP_002381452.1 218547661 7122417 complement(254242..255600) 1 NC_011740.1 catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall; membrane-bound lytic murein transglycosylase D 255600 mltD 7122417 mltD Escherichia fergusonii ATCC 35469 membrane-bound lytic murein transglycosylase D YP_002381452.1 254242 R 585054 CDS YP_002381453.1 218547662 7120940 complement(255672..256427) 1 NC_011740.1 catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione; hydroxyacylglutathione hydrolase 256427 gloB 7120940 gloB Escherichia fergusonii ATCC 35469 hydroxyacylglutathione hydrolase YP_002381453.1 255672 R 585054 CDS YP_002381454.1 218547663 7123661 256461..257183 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; S-adenosyl-L-methionine-dependent methyltransferase 257183 yafS 7123661 yafS Escherichia fergusonii ATCC 35469 S-adenosyl-L-methionine-dependent methyltransferase YP_002381454.1 256461 D 585054 CDS YP_002381455.1 218547664 7124036 complement(257180..257647) 1 NC_011740.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 257647 rnhA 7124036 rnhA Escherichia fergusonii ATCC 35469 ribonuclease H YP_002381455.1 257180 R 585054 CDS YP_002381456.1 218547665 7121427 257712..258443 1 NC_011740.1 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 258443 dnaQ 7121427 dnaQ Escherichia fergusonii ATCC 35469 DNA polymerase III subunit epsilon YP_002381456.1 257712 D 585054 CDS YP_002381457.1 218547666 7120049 complement(258751..259521) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8526497; Product type pe : enzyme; hypothetical protein 259521 yafV 7120049 yafV Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381457.1 258751 R 585054 CDS YP_002381458.1 218547667 7122424 259675..260148 1 NC_011740.1 inactivates vertebrate C-type lysozyme; C-lysozyme inhibitor 260148 ivy 7122424 ivy Escherichia fergusonii ATCC 35469 C-lysozyme inhibitor YP_002381458.1 259675 D 585054 CDS YP_002381459.1 218547668 7120798 complement(260191..262635) 1 NC_011740.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase 262635 fadE 7120798 fadE Escherichia fergusonii ATCC 35469 acyl-CoA dehydrogenase YP_002381459.1 260191 R 585054 CDS YP_002381460.1 218547669 7119988 262875..263453 1 NC_011740.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 263453 gmhA 7119988 gmhA Escherichia fergusonii ATCC 35469 phosphoheptose isomerase YP_002381460.1 262875 D 585054 CDS YP_002381461.1 218547670 7120848 263658..264425 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; class-II glutamine amidotransferase 264425 yafJ 7120848 yafJ Escherichia fergusonii ATCC 35469 class-II glutamine amidotransferase YP_002381461.1 263658 D 585054 CDS YP_002381462.1 218547671 7122418 complement(264396..265136) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 265136 yafK 7122418 yafK Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381462.1 264396 R 585054 CDS YP_002381463.1 218547672 7122419 265428..266186 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hydrolase 266186 yafL 7122419 yafL Escherichia fergusonii ATCC 35469 hydrolase YP_002381463.1 265428 D 585054 CDS YP_002381464.1 218547673 7122420 complement(266249..267580) 1 NC_011740.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 267580 argA 7122420 argA Escherichia fergusonii ATCC 35469 N-acetylglutamate synthase YP_002381464.1 266249 R 585054 CDS YP_002381465.1 218547674 7120536 267812..269065 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12787347, 21348478; Product type e : enzyme; N-acetylmuramoyl-L-alanine amidase 269065 amiC 7120536 amiC Escherichia fergusonii ATCC 35469 N-acetylmuramoyl-L-alanine amidase YP_002381465.1 267812 D 585054 CDS YP_002381466.1 218547675 7124006 269645..270742 1 NC_011740.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A 270742 mltA 7124006 mltA Escherichia fergusonii ATCC 35469 murein transglycosylase A YP_002381466.1 269645 D 585054 CDS YP_002381467.1 218547676 7120938 270819..271625 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 271625 ygdL 7120938 ygdL Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381467.1 270819 D 585054 CDS YP_002381468.1 218547677 7123877 complement(271676..272119) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; Fe-S metabolism protein 272119 ygdK 7123877 ygdK Escherichia fergusonii ATCC 35469 Fe-S metabolism protein YP_002381468.1 271676 R 585054 CDS YP_002381469.1 218547678 7121503 complement(272119..273324) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15148362, 9278392, 10739946, 10829016; Product type e : enzyme; cysteine sulfinate desulfinase 273324 csdA 7121503 csdA Escherichia fergusonii ATCC 35469 cysteine sulfinate desulfinase YP_002381469.1 272119 R 585054 CDS YP_002381470.1 218547679 7122810 273513..273740 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 273740 ygdI 7122810 ygdI Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381470.1 273513 D 585054 CDS YP_002381471.1 218547680 7120179 274091..275008 1 NC_011740.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA 275008 gcvA 7120179 gcvA Escherichia fergusonii ATCC 35469 DNA-binding transcriptional activator GcvA YP_002381471.1 274091 D 585054 CDS YP_002381472.1 218547681 7120178 275027..275422 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 7704273; Product type pm : membrane component; hypothetical protein 275422 ygdD 7120178 ygdD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381472.1 275027 D 585054 CDS YP_002381473.1 218547682 7123876 275415..276515 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 21188420, 7704273; Product type pe : enzyme; RNA 2'-O-ribose methyltransferase 276515 ygdE 7123876 ygdE Escherichia fergusonii ATCC 35469 RNA 2'-O-ribose methyltransferase YP_002381473.1 275415 D 585054 CDS YP_002381474.1 218547683 7121500 complement(276569..277414) 1 NC_011740.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups; exonuclease IX 277414 xni 7121500 xni Escherichia fergusonii ATCC 35469 exonuclease IX YP_002381474.1 276569 R 585054 CDS YP_002381475.1 218547684 7119975 complement(277436..278803) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91193203, 93215657, 8385012; Product type e : enzyme; L-serine deaminase II 278803 sdaB 7119975 sdaB Escherichia fergusonii ATCC 35469 L-serine deaminase II YP_002381475.1 277436 R 585054 CDS YP_002381476.1 218547685 7121754 complement(278861..280150) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8752353, 8026499; Product type pt : transporter; serine transporter 280150 sdaC 7121754 sdaC Escherichia fergusonii ATCC 35469 serine transporter YP_002381476.1 278861 R 585054 CDS YP_002381477.1 218547686 7121755 complement(280702..282066) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 282066 ygdH 7121755 ygdH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381477.1 280702 R 585054 CDS YP_002381478.1 218547687 7121501 complement(282182..283030) 1 NC_011740.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 283030 queF 7121501 queF Escherichia fergusonii ATCC 35469 7-cyano-7-deazaguanine reductase YP_002381478.1 282182 R 585054 CDS YP_002381479.1 218547688 7123465 283099..283644 1 NC_011740.1 SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function; SecY interacting protein Syd 283644 syd 7123465 syd Escherichia fergusonii ATCC 35469 SecY interacting protein Syd YP_002381479.1 283099 D 585054 CDS YP_002381480.1 218547689 7123539 284069..284602 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 284602 7123539 EFER_0269 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381480.1 284069 D 585054 CDS YP_002381481.1 218547690 7120775 284602..285384 1 NC_011740.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C 285384 truC 7120775 truC Escherichia fergusonii ATCC 35469 tRNA pseudouridine synthase C YP_002381481.1 284602 D 585054 CDS YP_002381482.1 218547691 7122170 285402..285848 1 NC_011740.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 285848 yqcA 7122170 yqcA Escherichia fergusonii ATCC 35469 flavodoxin YP_002381482.1 285402 D 585054 CDS YP_002381483.1 218547692 7119721 complement(285945..286943) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 286943 7119721 EFER_0272 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381483.1 285945 R 585054 CDS YP_002381484.1 218547693 7120776 complement(286944..288446) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 288446 7120776 EFER_0273 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381484.1 286944 R 585054 CDS YP_002381485.1 218547694 7120777 complement(288471..288950) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 288950 7120777 EFER_0274 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381485.1 288471 R 585054 CDS YP_002381486.1 218547695 7123219 289716..291056 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 9772162; Product type e : enzyme; glucarate dehydratase 291056 gudX 7123219 gudX Escherichia fergusonii ATCC 35469 glucarate dehydratase YP_002381486.1 289716 D 585054 CDS YP_002381487.1 218547696 7120626 291077..292417 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20233700, 9772162, 10762278, 13971911; Product type e : enzyme; (D)-glucarate dehydratase 1 292417 gudD 7120626 gudD Escherichia fergusonii ATCC 35469 (D)-glucarate dehydratase 1 YP_002381487.1 291077 D 585054 CDS YP_002381488.1 218547697 7120625 292506..293660 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; glycerate kinase 293660 7120625 EFER_0277 Escherichia fergusonii ATCC 35469 glycerate kinase YP_002381488.1 292506 D 585054 CDS YP_002381489.1 218547698 7120778 complement(293775..296531) 1 NC_011740.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; hybrid sensory histidine kinase BarA 296531 barA 7120778 barA Escherichia fergusonii ATCC 35469 hybrid sensory histidine kinase BarA YP_002381489.1 293775 R 585054 CDS YP_002381490.1 218547699 7121644 296588..297886 1 NC_011740.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase 297886 rumA 7121644 rumA Escherichia fergusonii ATCC 35469 23S rRNA 5-methyluridine methyltransferase YP_002381490.1 296588 D 585054 CDS YP_002381491.1 218547700 7123277 297937..300171 1 NC_011740.1 (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP; GDP/GTP pyrophosphokinase 300171 relA 7123277 relA Escherichia fergusonii ATCC 35469 GDP/GTP pyrophosphokinase YP_002381491.1 297937 D 585054 CDS YP_002381492.1 218547701 7123859 300249..300497 1 NC_011740.1 part of the MazF-MazE toxin-antitoxin system; conteracts MazF; antitoxin MazE 300497 chpR 7123859 chpR Escherichia fergusonii ATCC 35469 antitoxin MazE YP_002381492.1 300249 D 585054 CDS YP_002381493.1 218547702 7123769 300497..300832 1 NC_011740.1 MazF; endoribonuclease; toxin of the ChpA-ChpR toxin-antitoxin system; toxin ChpA 300832 chpA 7123769 chpA Escherichia fergusonii ATCC 35469 toxin ChpA YP_002381493.1 300497 D 585054 CDS YP_002381494.1 218547703 7123236 300903..301694 1 NC_011740.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase 301694 mazG 7123236 mazG Escherichia fergusonii ATCC 35469 nucleoside triphosphate pyrophosphohydrolase YP_002381494.1 300903 D 585054 CDS YP_002381495.1 218547704 7121235 301922..303559 1 NC_011740.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 303559 pyrG 7121235 pyrG Escherichia fergusonii ATCC 35469 CTP synthetase YP_002381495.1 301922 D 585054 CDS YP_002381496.1 218547705 7122336 303647..304945 1 NC_011740.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 304945 eno 7122336 eno Escherichia fergusonii ATCC 35469 phosphopyruvate hydratase YP_002381496.1 303647 D 585054 CDS YP_002381497.1 218547706 7122949 complement(305000..306328) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; IS4 transposase; KpLE2 phage-like element 306328 insG 7122949 insG Escherichia fergusonii ATCC 35469 IS4 transposase; KpLE2 phage-like element YP_002381497.1 305000 R 585054 CDS YP_002381498.1 218547707 7123213 complement(306396..306635) 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 306635 7123213 EFER_0287 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381498.1 306396 R 585054 CDS YP_002381499.1 218547708 7120779 complement(306445..307329) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 307329 7120779 EFER_0288 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381499.1 306445 R 585054 CDS YP_002381500.1 218547709 7123751 complement(307323..308471) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 308471 7123751 EFER_0290 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381500.1 307323 R 585054 CDS YP_002381501.1 218547710 7120780 complement(308486..309418) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 309418 ygcG 7120780 ygcG Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381501.1 308486 R 585054 CDS YP_002381502.1 218547711 7121494 complement(309408..310010) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 310010 7121494 EFER_0292 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381502.1 309408 R 585054 CDS YP_002381503.1 218547712 7120781 310183..310854 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 310854 ygcF 7120781 ygcF Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381503.1 310183 D 585054 CDS YP_002381504.1 218547713 7121493 311404..311547 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 311547 7121493 EFER_0294 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381504.1 311404 D 585054 CDS YP_002381505.1 218547714 7123752 312262..312525 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 312525 7123752 EFER_0295 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381505.1 312262 D 585054 CDS YP_002381506.1 218547715 7120782 complement(312886..313251) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12123838; Product type e : enzyme; 6-pyruvoyl tetrahydrobiopterin synthase 313251 ygcM 7120782 ygcM Escherichia fergusonii ATCC 35469 6-pyruvoyl tetrahydrobiopterin synthase YP_002381506.1 312886 R 585054 CDS YP_002381507.1 218547716 7121499 313567..315366 1 NC_011740.1 catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity; sulfite reductase subunit alpha 315366 cysJ 7121499 cysJ Escherichia fergusonii ATCC 35469 sulfite reductase subunit alpha YP_002381507.1 313567 D 585054 CDS YP_002381508.1 218547717 7122852 315366..317078 1 NC_011740.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta 317078 cysI 7122852 cysI Escherichia fergusonii ATCC 35469 sulfite reductase subunit beta YP_002381508.1 315366 D 585054 CDS YP_002381509.1 218547718 7123543 317142..317876 1 NC_011740.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase 317876 cysH 7123543 cysH Escherichia fergusonii ATCC 35469 phosphoadenosine phosphosulfate reductase YP_002381509.1 317142 D 585054 CDS YP_002381510.1 218547719 7122851 318234..320900 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pe : enzyme; hypothetical protein 320900 ygcB 7122851 ygcB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381510.1 318234 D 585054 CDS YP_002381511.1 218547720 7121492 321315..322823 1 NC_011740.1 unknown function; in E. coli this protein is regulated by BaeR, a protein involved in resistance to novobiocin and deoxycholate; hypothetical protein 322823 ygcL 7121492 ygcL Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381511.1 321315 D 585054 CDS YP_002381512.1 218547721 7123329 322816..323298 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 323298 ygcK 7123329 ygcK Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381512.1 322816 D 585054 CDS YP_002381513.1 218547722 7121498 323311..324402 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 324402 ygcJ 7121498 ygcJ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381513.1 323311 D 585054 CDS YP_002381514.1 218547723 7121497 324405..325079 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 325079 ygcI 7121497 ygcI Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381514.1 324405 D 585054 CDS YP_002381515.1 218547724 7121496 325066..325665 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 325665 ygcH 7121496 ygcH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381515.1 325066 D 585054 CDS YP_002381516.1 218547725 7121495 325681..326598 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 326598 ygbT 7121495 ygbT Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381516.1 325681 D 585054 CDS YP_002381517.1 218547726 7121491 326600..326884 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 326884 ygbF 7121491 ygbF Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381517.1 326600 D 585054 CDS YP_002381518.1 218547727 7121490 complement(327389..327538) 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 327538 7121490 EFER_0310 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381518.1 327389 R 585054 CDS YP_002381519.1 218547728 7120783 complement(327519..327635) 1 NC_011740.1 hypothetical protein 327635 7120783 EFER_0311 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381519.1 327519 R 585054 CDS YP_002381521.1 218547730 7120784 complement(328260..329297) 1 NC_011740.1 catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3; alkaline phosphatase isozyme conversion aminopeptidase 329297 iap 7120784 iap Escherichia fergusonii ATCC 35469 alkaline phosphatase isozyme conversion aminopeptidase YP_002381521.1 328260 R 585054 CDS YP_002381522.1 218547731 7120717 329549..330457 1 NC_011740.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 330457 cysD 7120717 cysD Escherichia fergusonii ATCC 35469 sulfate adenylyltransferase subunit 2 YP_002381522.1 329549 D 585054 CDS YP_002381523.1 218547732 7122848 330459..331886 1 NC_011740.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ; sulfate adenylyltransferase subunit 1 331886 cysN 7122848 cysN Escherichia fergusonii ATCC 35469 sulfate adenylyltransferase subunit 1 YP_002381523.1 330459 D 585054 CDS YP_002381524.1 218547733 7122964 331886..332491 1 NC_011740.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis; adenylylsulfate kinase 332491 cysC 7122964 cysC Escherichia fergusonii ATCC 35469 adenylylsulfate kinase YP_002381524.1 331886 D 585054 CDS YP_002381525.1 218547734 7122847 332505..332864 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 332864 ygbE 7122847 ygbE Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381525.1 332505 D 585054 CDS YP_002381526.1 218547735 7123875 333039..333350 1 NC_011740.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB 333350 ftsB 7123875 ftsB Escherichia fergusonii ATCC 35469 cell division protein FtsB YP_002381526.1 333039 D 585054 CDS YP_002381527.1 218547736 7120147 333369..334079 1 NC_011740.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 334079 ispD 7120147 ispD Escherichia fergusonii ATCC 35469 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_002381527.1 333369 D 585054 CDS YP_002381528.1 218547737 7120792 334079..334558 1 NC_011740.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclo diphosphate synthase 334558 ispF 7120792 ispF Escherichia fergusonii ATCC 35469 2-C-methyl-D-erythritol 2,4-cyclo diphosphate synthase YP_002381528.1 334079 D 585054 CDS YP_002381529.1 218547738 7123754 334555..335604 1 NC_011740.1 catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 335604 truD 7123754 truD Escherichia fergusonii ATCC 35469 tRNA pseudouridine synthase D YP_002381529.1 334555 D 585054 CDS YP_002381530.1 218547739 7122171 335585..336346 1 NC_011740.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 336346 surE 7122171 surE Escherichia fergusonii ATCC 35469 stationary phase survival protein SurE YP_002381530.1 335585 D 585054 CDS YP_002381531.1 218547740 7121968 336340..336966 1 NC_011740.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase 336966 pcm 7121968 pcm Escherichia fergusonii ATCC 35469 protein-L-isoaspartate O-methyltransferase YP_002381531.1 336340 D 585054 CDS YP_002381532.1 218547741 7122565 complement(337084..337299) 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 337299 7122565 EFER_0326 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381532.1 337084 R 585054 CDS YP_002381533.1 218547742 7120785 337109..338251 1 NC_011740.1 outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus; lipoprotein NlpD 338251 nlpD 7120785 nlpD Escherichia fergusonii ATCC 35469 lipoprotein NlpD YP_002381533.1 337109 D 585054 CDS YP_002381534.1 218547743 7120760 338431..339306 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12052558, 14671322, 91294193, 94032222, 94179109, 1437569, 2690013, 8208244, 8475100 -!-9006056; Product type f : factor; RNA polymerase, sigma S (sigma 38) factor 339306 rpoS 7120760 rpoS Escherichia fergusonii ATCC 35469 RNA polymerase, sigma S (sigma 38) factor YP_002381534.1 338431 D 585054 CDS YP_002381535.1 218547744 7123812 complement(339427..339867) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15731069; Product type r : regulator; transcriptional regulator hosA 339867 7123812 EFER_0329 Escherichia fergusonii ATCC 35469 transcriptional regulator hosA YP_002381535.1 339427 R 585054 CDS YP_002381536.1 218547745 7123221 339981..340574 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15979273; Product type e : enzyme; hypothetical protein 340574 7123221 EFER_0330 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381536.1 339981 D 585054 CDS YP_002381537.1 218547746 7120786 340574..342001 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15979273; Product type e : enzyme; hypothetical protein 342001 7120786 EFER_0331 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381537.1 340574 D 585054 CDS YP_002381538.1 218547747 7120787 342012..342248 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15979273; Product type e : enzyme; hypothetical protein 342248 7120787 EFER_0332 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381538.1 342012 D 585054 CDS YP_002381539.1 218547748 7120788 complement(342290..342946) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9130712; Product type e : enzyme; serine/threonine-specific protein phosphatase 2 342946 pphB 7120788 pphB Escherichia fergusonii ATCC 35469 serine/threonine-specific protein phosphatase 2 YP_002381539.1 342290 R 585054 CDS YP_002381540.1 218547749 7120112 complement(343052..345613) 1 NC_011740.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 345613 mutS 7120112 mutS Escherichia fergusonii ATCC 35469 DNA mismatch repair protein MutS YP_002381540.1 343052 R 585054 CDS YP_002381541.1 218547750 7120654 complement(345852..346805) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10708387, 15805518; Product type r : regulator; Ery operon repressor 346805 eryD 7120654 eryD Escherichia fergusonii ATCC 35469 Ery operon repressor YP_002381541.1 345852 R 585054 CDS YP_002381542.1 218547751 7119963 complement(346832..347944) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10708387, 15805518; Product type e : enzyme; D-erythrulose-phosphate dehydrogenase 347944 eryC 7119963 eryC Escherichia fergusonii ATCC 35469 D-erythrulose-phosphate dehydrogenase YP_002381542.1 346832 R 585054 CDS YP_002381543.1 218547752 7119962 complement(347775..349310) 1 NC_011740.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 349310 eryB 7119962 eryB Escherichia fergusonii ATCC 35469 glycerol-3-phosphate dehydrogenase YP_002381543.1 347775 R 585054 CDS YP_002381544.1 218547753 7122965 complement(349319..350881) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10708387, 15805518; Product type e : enzyme; erythritol kinase 350881 eryA 7122965 eryA Escherichia fergusonii ATCC 35469 erythritol kinase YP_002381544.1 349319 R 585054 CDS YP_002381545.1 218547754 7122963 351135..351941 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; lipoprotein 351941 7122963 EFER_0339 Escherichia fergusonii ATCC 35469 lipoprotein YP_002381545.1 351135 D 585054 CDS YP_002381546.1 218547755 7120789 351938..353482 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; sugar ABC transporter ATP-binding protein 353482 7120789 EFER_0340 Escherichia fergusonii ATCC 35469 sugar ABC transporter ATP-binding protein YP_002381546.1 351938 D 585054 CDS YP_002381547.1 218547756 7123753 353479..354555 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; sugar ABC transporter membrane protein 354555 7123753 EFER_0341 Escherichia fergusonii ATCC 35469 sugar ABC transporter membrane protein YP_002381547.1 353479 D 585054 CDS YP_002381548.1 218547757 7123868 354642..355592 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; sugar ABC transporter substrate-binding protein 355592 7123868 EFER_0342 Escherichia fergusonii ATCC 35469 sugar ABC transporter substrate-binding protein YP_002381548.1 354642 D 585054 CDS YP_002381549.1 218547758 7121566 355597..356532 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator of sugar metabolism, DeoR family 356532 7121566 EFER_0343 Escherichia fergusonii ATCC 35469 transcriptional regulator of sugar metabolism, DeoR family YP_002381549.1 355597 D 585054 CDS YP_002381550.1 218547759 7121567 356678..357067 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 357067 ygbA 7121567 ygbA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381550.1 356678 D 585054 CDS YP_002381551.1 218547760 7123328 complement(357088..357516) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; molybdenum-pterin-binding-protein 357516 7123328 EFER_0345 Escherichia fergusonii ATCC 35469 molybdenum-pterin-binding-protein YP_002381551.1 357088 R 585054 CDS YP_002381552.1 218547761 7121568 complement(357548..359638) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20307603, 21557168, 90368529, 92140045, 94018617, 2118503, 2280686; Product type r : regulator; DNA-binding transcriptional activator 359638 fhlA 7121568 fhlA Escherichia fergusonii ATCC 35469 DNA-binding transcriptional activator YP_002381552.1 357548 R 585054 CDS YP_002381553.1 218547762 7120011 complement(359786..360754) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91194542, 9485446, 1849603; Product type e : enzyme; carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein 360754 hypE 7120011 hypE Escherichia fergusonii ATCC 35469 carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein YP_002381553.1 359786 R 585054 CDS YP_002381554.1 218547763 7120715 complement(360793..361914) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91194542, 92255260, 1849603; Product type f : factor; hydrogenase maturation protein 361914 hypD 7120715 hypD Escherichia fergusonii ATCC 35469 hydrogenase maturation protein YP_002381554.1 360793 R 585054 CDS YP_002381555.1 218547764 7120714 complement(361914..362186) 1 NC_011740.1 HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase; hydrogenase assembly chaperone 362186 hypC 7120714 hypC Escherichia fergusonii ATCC 35469 hydrogenase assembly chaperone YP_002381555.1 361914 R 585054 CDS YP_002381556.1 218547765 7123740 complement(362177..363049) 1 NC_011740.1 GTP hydrolase involved in nickel liganding into hydrogenases; hydrogenase nickel incorporation protein HypB 363049 hypB 7123740 hypB Escherichia fergusonii ATCC 35469 hydrogenase nickel incorporation protein HypB YP_002381556.1 362177 R 585054 CDS YP_002381557.1 218547766 7120713 complement(363053..363403) 1 NC_011740.1 plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein 363403 hypA 7120713 hypA Escherichia fergusonii ATCC 35469 hydrogenase nickel incorporation protein YP_002381557.1 363053 R 585054 CDS YP_002381558.1 218547767 7120712 363617..364078 1 NC_011740.1 regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon; formate hydrogenlyase regulatory protein HycA 364078 hycA 7120712 hycA Escherichia fergusonii ATCC 35469 formate hydrogenlyase regulatory protein HycA YP_002381558.1 363617 D 585054 CDS YP_002381559.1 218547768 7120702 364221..364832 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90251163, 92215587, 92326636, 2187144; Product type c : carrier; hydrogenase 3, Fe-S subunit 364832 hycB 7120702 hycB Escherichia fergusonii ATCC 35469 hydrogenase 3, Fe-S subunit YP_002381559.1 364221 D 585054 CDS YP_002381560.1 218547769 7120703 364829..366655 1 NC_011740.1 catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3); formate hydrogenlyase subunit 3 366655 hycC 7120703 hycC Escherichia fergusonii ATCC 35469 formate hydrogenlyase subunit 3 YP_002381560.1 364829 D 585054 CDS YP_002381561.1 218547770 7120704 366658..367581 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90251163, 92215587, 92326636; Product type m : membrane component; hydrogenase 3, membrane subunit 367581 hycD 7120704 hycD Escherichia fergusonii ATCC 35469 hydrogenase 3, membrane subunit YP_002381561.1 366658 D 585054 CDS YP_002381562.1 218547771 7123737 367599..369308 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92215587, 92326636, 94170785, 2187144, 8125094; Product type e : enzyme; hydrogenase 3, large subunit 369308 hycE 7123737 hycE Escherichia fergusonii ATCC 35469 hydrogenase 3, large subunit YP_002381562.1 367599 D 585054 CDS YP_002381563.1 218547772 7120705 369318..369860 1 NC_011740.1 electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate; formate hydrogenlyase complex iron-sulfur subunit 369860 hycF 7120705 hycF Escherichia fergusonii ATCC 35469 formate hydrogenlyase complex iron-sulfur subunit YP_002381563.1 369318 D 585054 CDS YP_002381564.1 218547773 7123206 369860..370627 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90251163, 92215587, 92326636, 2187144; Product type e : enzyme; hydrogenase 3 and formate hydrogenase complex, HycG subunit 370627 hycG 7123206 hycG Escherichia fergusonii ATCC 35469 hydrogenase 3 and formate hydrogenase complex, HycG subunit YP_002381564.1 369860 D 585054 CDS YP_002381565.1 218547774 7120706 370624..371034 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92215587, 92326636, 1625581, 2187144, 7851435; Product type f : factor; hydrogenase-3 maturation protein 371034 hycH 7120706 hycH Escherichia fergusonii ATCC 35469 hydrogenase-3 maturation protein YP_002381565.1 370624 D 585054 CDS YP_002381566.1 218547775 7120707 371027..371497 1 NC_011740.1 involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE; hydrogenase 3 maturation protease 371497 hycI 7120707 hycI Escherichia fergusonii ATCC 35469 hydrogenase 3 maturation protease YP_002381566.1 371027 D 585054 CDS YP_002381567.1 218547776 7123207 complement(371656..373080) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88297127, 92334140, 1630307; Product type e : enzyme; cryptic 6-phospho-beta-glucosidase 373080 ascB 7123207 ascB Escherichia fergusonii ATCC 35469 cryptic 6-phospho-beta-glucosidase YP_002381567.1 371656 R 585054 CDS YP_002381568.1 218547777 7120561 complement(373089..374546) 1 NC_011740.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system cellobiose/arbutin/salicin-specific transporter subunit IIBC 374546 ascF 7120561 ascF Escherichia fergusonii ATCC 35469 PTS system cellobiose/arbutin/salicin-specific transporter subunit IIBC YP_002381568.1 373089 R 585054 CDS YP_002381569.1 218547778 7123181 374803..375816 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88297127, 92334140, 1630307; Product type r : regulator; DNA-binding transcriptional repressor 375816 ascG 7123181 ascG Escherichia fergusonii ATCC 35469 DNA-binding transcriptional repressor YP_002381569.1 374803 D 585054 CDS YP_002381570.1 218547779 7120562 375965..376492 1 NC_011740.1 involved in electron transport from formate to hydrogen; electron transport protein HydN 376492 hydN 7120562 hydN Escherichia fergusonii ATCC 35469 electron transport protein HydN YP_002381570.1 375965 D 585054 CDS YP_002381571.1 218547780 7120708 376645..378897 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12377778, 92255260, 8661925; Product type e : enzyme; carbamoyl phosphate phosphatase 378897 hypF 7120708 hypF Escherichia fergusonii ATCC 35469 carbamoyl phosphate phosphatase YP_002381571.1 376645 D 585054 CDS YP_002381572.1 218547781 7121685 complement(379024..380157) 1 NC_011740.1 catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase; nitric oxide reductase 380157 norW 7121685 norW Escherichia fergusonii ATCC 35469 nitric oxide reductase YP_002381572.1 379024 R 585054 CDS YP_002381573.1 218547782 7119656 complement(380154..381593) 1 NC_011740.1 detoxifies nitric oxide using NADH; anaerobic nitric oxide reductase flavorubredoxin 381593 norV 7119656 norV Escherichia fergusonii ATCC 35469 anaerobic nitric oxide reductase flavorubredoxin YP_002381573.1 380154 R 585054 CDS YP_002381574.1 218547783 7119655 381780..383294 1 NC_011740.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon; anaerobic nitric oxide reductase transcriptional regulator 383294 norR 7119655 norR Escherichia fergusonii ATCC 35469 anaerobic nitric oxide reductase transcriptional regulator YP_002381574.1 381780 D 585054 CDS YP_002381575.1 218547784 7119654 complement(383291..384256) 1 NC_011740.1 catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate; D-arabinose 5-phosphate isomerase 384256 gutQ 7119654 gutQ Escherichia fergusonii ATCC 35469 D-arabinose 5-phosphate isomerase YP_002381575.1 383291 R 585054 CDS YP_002381576.1 218547785 7120627 384510..385595 1 NC_011740.1 membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan; murein hydrolase B 385595 mltB 7120627 mltB Escherichia fergusonii ATCC 35469 murein hydrolase B YP_002381576.1 384510 D 585054 CDS YP_002381577.1 218547786 7120939 complement(385634..386131) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 386131 7120939 EFER_0373 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381577.1 385634 R 585054 CDS YP_002381578.1 218547787 7123889 386056..386553 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; competence damage-inducible protein A 386553 ygaD 7123889 ygaD Escherichia fergusonii ATCC 35469 competence damage-inducible protein A YP_002381578.1 386056 D 585054 CDS YP_002381579.1 218547788 7121481 386633..387694 1 NC_011740.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 387694 recA 7121481 recA Escherichia fergusonii ATCC 35469 recombinase A YP_002381579.1 386633 D 585054 CDS YP_002381580.1 218547789 7122358 387762..388262 1 NC_011740.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 388262 recX 7122358 recX Escherichia fergusonii ATCC 35469 recombination regulator RecX YP_002381580.1 387762 D 585054 CDS YP_002381581.1 218547790 7121385 388390..391020 1 NC_011740.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 391020 alaS 7121385 alaS Escherichia fergusonii ATCC 35469 alanyl-tRNA synthetase YP_002381581.1 388390 D 585054 CDS YP_002381582.1 218547791 7122291 391255..391440 1 NC_011740.1 affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator 391440 csrA 7122291 csrA Escherichia fergusonii ATCC 35469 carbon storage regulator YP_002381582.1 391255 D 585054 CDS YP_002381583.1 218547792 7122243 392897..393463 1 NC_011740.1 YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent; fructose-1-phosphatase 393463 yqaB 7122243 yqaB Escherichia fergusonii ATCC 35469 fructose-1-phosphatase YP_002381583.1 392897 D 585054 CDS YP_002381584.1 218547793 7119719 393460..393888 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 393888 yqaA 7119719 yqaA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381584.1 393460 D 585054 CDS YP_002381585.1 218547794 7119718 393961..395517 1 NC_011740.1 involved in the first step of glutathione biosynthesis; glutamate--cysteine ligase 395517 gshA 7119718 gshA Escherichia fergusonii ATCC 35469 glutamate--cysteine ligase YP_002381585.1 393961 D 585054 CDS YP_002381586.1 218547795 7120930 395667..396182 1 NC_011740.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 396182 luxS 7120930 luxS Escherichia fergusonii ATCC 35469 S-ribosylhomocysteinase YP_002381586.1 395667 D 585054 CDS YP_002381587.1 218547796 7123284 complement(396233..397345) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; RNA related enzyme 397345 7123284 EFER_0383 Escherichia fergusonii ATCC 35469 RNA related enzyme YP_002381587.1 396233 R 585054 CDS YP_002381588.1 218547797 7121569 complement(397342..398049) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 398049 7121569 EFER_0384 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381588.1 397342 R 585054 CDS YP_002381589.1 218547798 7121570 complement(398307..399845) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21450803, 93285984, 94262163, 1409590; Product type t : transporter; multidrug efflux system protein 399845 emrB 7121570 emrB Escherichia fergusonii ATCC 35469 multidrug efflux system protein YP_002381589.1 398307 R 585054 CDS YP_002381590.1 218547799 7122946 complement(399862..401034) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21450803, 93285984, 94262163, 1409590, 8203018; Product type t : transporter; multidrug efflux system 401034 emrA 7122946 emrA Escherichia fergusonii ATCC 35469 multidrug efflux system YP_002381590.1 399862 R 585054 CDS YP_002381591.1 218547800 7123559 complement(401161..401691) 1 NC_011740.1 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB; transcriptional repressor MprA 401691 mprA 7123559 mprA Escherichia fergusonii ATCC 35469 transcriptional repressor MprA YP_002381591.1 401161 R 585054 CDS YP_002381592.1 218547801 7120961 complement(401782..402117) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 402117 ygaH 7120961 ygaH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381592.1 401782 R 585054 CDS YP_002381593.1 218547802 7121483 complement(402107..402844) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter 402844 ygaZ 7121483 ygaZ Escherichia fergusonii ATCC 35469 transporter YP_002381593.1 402107 R 585054 CDS YP_002381594.1 218547803 7121489 complement(402969..404153) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16000740; Product type pt : transporter; transporter 404153 7121489 EFER_0390 Escherichia fergusonii ATCC 35469 transporter YP_002381594.1 402969 R 585054 CDS YP_002381595.1 218547804 7123342 complement(404345..405337) 1 NC_011740.1 with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine; glycine betaine transporter periplasmic subunit 405337 proX 7123342 proX Escherichia fergusonii ATCC 35469 glycine betaine transporter periplasmic subunit YP_002381595.1 404345 R 585054 CDS YP_002381596.1 218547805 7120137 complement(405395..406459) 1 NC_011740.1 with ProVX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter membrane protein 406459 proW 7120137 proW Escherichia fergusonii ATCC 35469 glycine betaine transporter membrane protein YP_002381596.1 405395 R 585054 CDS YP_002381597.1 218547806 7120136 complement(406452..407654) 1 NC_011740.1 with ProWX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter ATP-binding subunit 407654 proV 7120136 proV Escherichia fergusonii ATCC 35469 glycine betaine transporter ATP-binding subunit YP_002381597.1 406452 R 585054 CDS YP_002381598.1 218547807 7120135 complement(408010..408969) 1 NC_011740.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 408969 nrdF 7120135 nrdF Escherichia fergusonii ATCC 35469 ribonucleotide-diphosphate reductase subunit beta YP_002381598.1 408010 R 585054 CDS YP_002381599.1 218547808 7119661 complement(408979..411123) 1 NC_011740.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 411123 nrdE 7119661 nrdE Escherichia fergusonii ATCC 35469 ribonucleotide-diphosphate reductase subunit alpha YP_002381599.1 408979 R 585054 CDS YP_002381600.1 218547809 7119660 complement(411096..411506) 1 NC_011740.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 411506 nrdI 7119660 nrdI Escherichia fergusonii ATCC 35469 ribonucleotide reductase stimulatory protein YP_002381600.1 411096 R 585054 CDS YP_002381601.1 218547810 7119664 complement(411503..411748) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9218434, 11441020, 8820648; Product type pc : carrier; glutaredoxin-like protein 411748 nrdH 7119664 nrdH Escherichia fergusonii ATCC 35469 glutaredoxin-like protein YP_002381601.1 411503 R 585054 CDS YP_002381602.1 218547811 7119663 complement(411957..412388) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 412388 7119663 EFER_0398 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381602.1 411957 R 585054 CDS YP_002381603.1 218547812 7121571 412476..413810 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; bifunctional protein aminotransaminase/transcriptional regulator, GntR family 413810 7121571 EFER_0399 Escherichia fergusonii ATCC 35469 bifunctional protein aminotransaminase/transcriptional regulator, GntR family YP_002381603.1 412476 D 585054 CDS YP_002381604.1 218547813 7121572 complement(413866..414207) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 414207 ygaM 7121572 ygaM Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381604.1 413866 R 585054 CDS YP_002381605.1 218547814 7121484 414347..414691 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 7961433; hypothetical protein 414691 ygaC 7121484 ygaC Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381605.1 414347 D 585054 CDS YP_002381606.1 218547815 7123873 complement(414728..415267) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; inner membrane protein 415267 ygaW 7123873 ygaW Escherichia fergusonii ATCC 35469 inner membrane protein YP_002381606.1 414728 R 585054 CDS YP_002381607.1 218547816 7121488 415825..416226 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20485613, 93126121, 9643551, 98132400, 99415935, 1480493, 7961433; Product type r : regulator; DNA binding protein 416226 stpA 7121488 stpA Escherichia fergusonii ATCC 35469 DNA binding protein YP_002381607.1 415825 D 585054 CDS YP_002381608.1 218547817 7121952 complement(416273..416797) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pe : enzyme; hypothetical protein 416797 ygaP 7121952 ygaP Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381608.1 416273 R 585054 CDS YP_002381609.1 218547818 7123874 complement(416807..417106) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator 417106 ygaV 7123874 ygaV Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YP_002381609.1 416807 R 585054 CDS YP_002381610.1 218547819 7121487 417289..417447 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 417447 yqaE 7121487 yqaE Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381610.1 417289 D 585054 CDS YP_002381611.1 218547820 7119720 417531..417980 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; LysM domain/BON superfamily protein 417980 ygaU 7119720 ygaU Escherichia fergusonii ATCC 35469 LysM domain/BON superfamily protein YP_002381611.1 417531 D 585054 CDS YP_002381612.1 218547821 7121486 complement(417981..418643) 1 NC_011740.1 regulator of gab gene expression; DNA-binding transcriptional regulator CsiR 418643 csiR 7121486 csiR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator CsiR YP_002381612.1 417981 R 585054 CDS YP_002381613.1 218547822 7122816 complement(418664..420064) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94127927, 9685361, 8297211; Product type t : transporter; gamma-aminobutyrate transporter 420064 gabP 7122816 gabP Escherichia fergusonii ATCC 35469 gamma-aminobutyrate transporter YP_002381613.1 418664 R 585054 CDS YP_002381614.1 218547823 7120159 complement(420301..421581) 1 NC_011740.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 421581 gabT 7120159 gabT Escherichia fergusonii ATCC 35469 4-aminobutyrate aminotransferase YP_002381614.1 420301 R 585054 CDS YP_002381615.1 218547824 7120160 complement(421595..423043) 1 NC_011740.1 catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; succinate-semialdehyde dehydrogenase I 423043 gabD 7120160 gabD Escherichia fergusonii ATCC 35469 succinate-semialdehyde dehydrogenase I YP_002381615.1 421595 R 585054 CDS YP_002381616.1 218547825 7120158 complement(423066..424334) 1 NC_011740.1 catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase 424334 ygaF 7120158 ygaF Escherichia fergusonii ATCC 35469 hydroxyglutarate oxidase YP_002381616.1 423066 R 585054 CDS YP_002381617.1 218547826 7121482 complement(424354..425331) 1 NC_011740.1 in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution; hypothetical protein 425331 ygaT 7121482 ygaT Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381617.1 424354 R 585054 CDS YP_002381618.1 218547827 7120025 complement(426370..427302) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator 427302 yahB 7120025 yahB Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YP_002381618.1 426370 R 585054 CDS YP_002381619.1 218547828 7123796 complement(427394..427891) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 427891 yahC 7123796 yahC Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381619.1 427394 R 585054 CDS YP_002381620.1 218547829 7121042 428149..428754 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; protein with ankyrin domain 428754 yahD 7121042 yahD Escherichia fergusonii ATCC 35469 protein with ankyrin domain YP_002381620.1 428149 D 585054 CDS YP_002381621.1 218547830 7121043 428794..429657 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 429657 yahE 7121043 yahE Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381621.1 428794 D 585054 CDS YP_002381622.1 218547831 7121044 429647..431194 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 431194 yahF 7121044 yahF Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381622.1 429647 D 585054 CDS YP_002381623.1 218547832 7121045 431194..432612 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 432612 yahG 7121045 yahG Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381623.1 431194 D 585054 CDS YP_002381624.1 218547833 7121046 432708..433658 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7711027, 11523892; Product type pe : enzyme; carbamate kinase 433658 yahI 7121046 yahI Escherichia fergusonii ATCC 35469 carbamate kinase YP_002381624.1 432708 D 585054 CDS YP_002381625.1 218547834 7121047 433668..435059 1 NC_011740.1 metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain; deaminase 435059 yahJ 7121047 yahJ Escherichia fergusonii ATCC 35469 deaminase YP_002381625.1 433668 D 585054 CDS YP_002381626.1 218547835 7121048 complement(435140..435886) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; methyltransferase from phage 435886 yjhP 7121048 yjhP Escherichia fergusonii ATCC 35469 methyltransferase from phage YP_002381626.1 435140 R 585054 CDS YP_002381627.1 218547836 7122027 complement(435896..436210) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 436210 yjhX 7122027 yjhX Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381627.1 435896 R 585054 CDS YP_002381628.1 218547837 7121049 complement(437733..438716) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transaldolase A 438716 7121049 EFER_0427 Escherichia fergusonii ATCC 35469 transaldolase A YP_002381628.1 437733 R 585054 CDS YP_002381629.1 218547838 7121573 complement(438744..439202) 1 NC_011740.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 439202 7121573 EFER_0428 Escherichia fergusonii ATCC 35469 ribose-5-phosphate isomerase B YP_002381629.1 438744 R 585054 CDS YP_002381630.1 218547839 7121574 439460..440950 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; tartrate transporter 440950 7121574 EFER_0429 Escherichia fergusonii ATCC 35469 tartrate transporter YP_002381630.1 439460 D 585054 CDS YP_002381631.1 218547840 7121575 440952..442706 1 NC_011740.1 in some organisms the DhaK and DhaL subunits are encoded by separate genes; in others they are fused; functions along with DhaM to phosphorylate dihydroxyacetone; dihydroxyacetone kinase 442706 7121575 EFER_0430 Escherichia fergusonii ATCC 35469 dihydroxyacetone kinase YP_002381631.1 440952 D 585054 CDS YP_002381632.1 218547841 7121576 442697..443488 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; triosephosphate isomerase 443488 7121576 EFER_0431 Escherichia fergusonii ATCC 35469 triosephosphate isomerase YP_002381632.1 442697 D 585054 CDS YP_002381633.1 218547842 7123890 443485..444333 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; sugar phosphate isomerase/epimerase-like protein 444333 7123890 EFER_0432 Escherichia fergusonii ATCC 35469 sugar phosphate isomerase/epimerase-like protein YP_002381633.1 443485 D 585054 CDS YP_002381634.1 218547843 7121577 444290..445180 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; hypothetical protein 445180 7121577 EFER_0433 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381634.1 444290 D 585054 CDS YP_002381635.1 218547844 7123891 445265..446266 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator 446266 7123891 EFER_0434 Escherichia fergusonii ATCC 35469 transcriptional regulator YP_002381635.1 445265 D 585054 CDS YP_002381636.1 218547845 7121578 446452..446595 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 446595 7121578 EFER_0435 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381636.1 446452 D 585054 CDS YP_002381637.1 218547846 7121579 446547..446879 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 446879 7121579 EFER_0436 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381637.1 446547 D 585054 CDS YP_002381638.1 218547847 7123343 complement(446952..447194) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7665482; Product type e : enzyme; Virulence protein msgA, DinI-like family 447194 7123343 EFER_0437 Escherichia fergusonii ATCC 35469 Virulence protein msgA, DinI-like family YP_002381638.1 446952 R 585054 CDS YP_002381639.1 218547848 7121580 complement(447701..447853) 1 NC_011740.1 Evidence 6 : Doubtful CDS; Product type h : extrachromosomal origin; hypothetical protein 447853 7121580 EFER_0438 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381639.1 447701 R 585054 CDS YP_002381640.1 218547849 7121581 complement(448078..448296) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 448296 7121581 EFER_0439 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381640.1 448078 R 585054 CDS YP_002381641.1 218547850 7123344 complement(448502..450835) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3309336; Product type e : enzyme; phage DNA primase 450835 7123344 EFER_0440 Escherichia fergusonii ATCC 35469 phage DNA primase YP_002381641.1 448502 R 585054 CDS YP_002381642.1 218547851 7121582 complement(450850..451170) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 451170 7121582 EFER_0441 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381642.1 450850 R 585054 CDS YP_002381643.1 218547852 7121583 complement(451306..451761) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 451761 7121583 EFER_0442 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381643.1 451306 R 585054 CDS YP_002381644.1 218547853 7123892 complement(451754..452041) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 6095206; Product type h : extrachromosomal origin; derepression protein 452041 7123892 EFER_0443 Escherichia fergusonii ATCC 35469 derepression protein YP_002381644.1 451754 R 585054 CDS YP_002381645.1 218547854 7121584 complement(452034..452447) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 6095206; Product type h : extrachromosomal origin; regulator protein cI 452447 cI 7121584 cI Escherichia fergusonii ATCC 35469 regulator protein cI YP_002381645.1 452034 R 585054 CDS YP_002381646.1 218547855 7120891 complement(452630..452896) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; hypothetical protein 452896 7120891 EFER_0445 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381646.1 452630 R 585054 CDS YP_002381647.1 218547856 7121585 453384..454184 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7643390, 3295254; Product type h : extrachromosomal origin; glycoprotein 3 454184 7121585 EFER_0446 Escherichia fergusonii ATCC 35469 glycoprotein 3 YP_002381647.1 453384 D 585054 CDS YP_002381648.1 218547857 7123893 454181..454681 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; transactivation protein 454681 7123893 EFER_0447 Escherichia fergusonii ATCC 35469 transactivation protein YP_002381648.1 454181 D 585054 CDS YP_002381649.1 218547858 7121586 454755..455327 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3295254, 2193910; Product type h : extrachromosomal origin; Polarity suppression protein 455327 7121586 EFER_0448 Escherichia fergusonii ATCC 35469 Polarity suppression protein YP_002381649.1 454755 D 585054 CDS YP_002381650.1 218547859 7121587 complement(455527..457977) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 457977 7121587 EFER_0449 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381650.1 455527 R 585054 CDS YP_002381651.1 218547860 7123894 complement(458001..459200) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; phage integrase 459200 int 7123894 int Escherichia fergusonii ATCC 35469 phage integrase YP_002381651.1 458001 R 585054 CDS YP_002381653.1 218547862 7121588 complement(459964..460446) 1 NC_011740.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 460446 smpB 7121588 smpB Escherichia fergusonii ATCC 35469 SsrA-binding protein YP_002381653.1 459964 R 585054 CDS YP_002381654.1 218547863 7123376 460578..461054 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 461054 yfjG 7123376 yfjG Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381654.1 460578 D 585054 CDS YP_002381655.1 218547864 7121480 461044..461334 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 461334 yfjF 7121480 yfjF Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381655.1 461044 D 585054 CDS YP_002381656.1 218547865 7123327 complement(461394..461735) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 2045357; Product type lp : lipoprotein; hypothetical protein 461735 smpA 7123327 smpA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381656.1 461394 R 585054 CDS YP_002381657.1 218547866 7121795 complement(461884..463545) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87259985, 91355307, 95058623, 3037486; Product type cp : cell process; recombination and repair protein 463545 recN 7121795 recN Escherichia fergusonii ATCC 35469 recombination and repair protein YP_002381657.1 461884 R 585054 CDS YP_002381658.1 218547867 7121382 complement(463631..465259) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16511117, 16233126; Product type e : enzyme; inorganic polyphosphate/ATP-NAD kinase 465259 ppnK 7121382 ppnK Escherichia fergusonii ATCC 35469 inorganic polyphosphate/ATP-NAD kinase YP_002381658.1 463631 R 585054 CDS YP_002381659.1 218547868 7120115 464174..465226 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12639955, 1826368, 3045760; Product type f : factor; heat shock protein HSP70 cofactor 465226 grpE 7120115 grpE Escherichia fergusonii ATCC 35469 heat shock protein HSP70 cofactor YP_002381659.1 464174 D 585054 CDS YP_002381660.1 218547869 7120617 complement(465281..466477) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 466477 yfjD 7120617 yfjD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381660.1 465281 R 585054 CDS YP_002381661.1 218547870 7123326 complement(466588..467454) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 467454 ypjD 7123326 ypjD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381661.1 466588 R 585054 CDS YP_002381662.1 218547871 7123582 467546..468907 1 NC_011740.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; signal recognition particle protein 468907 ffh 7123582 ffh Escherichia fergusonii ATCC 35469 signal recognition particle protein YP_002381662.1 467546 D 585054 CDS YP_002381663.1 218547872 7120009 469044..469292 1 NC_011740.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 469292 rpsP 7120009 rpsP Escherichia fergusonii ATCC 35469 30S ribosomal protein S16 YP_002381663.1 469044 D 585054 CDS YP_002381664.1 218547873 7121137 469311..469859 1 NC_011740.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 469859 rimM 7121137 rimM Escherichia fergusonii ATCC 35469 16S rRNA-processing protein RimM YP_002381664.1 469311 D 585054 CDS YP_002381665.1 218547874 7121414 469890..470657 1 NC_011740.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 470657 trmD 7121414 trmD Escherichia fergusonii ATCC 35469 tRNA (guanine-N(1)-)-methyltransferase YP_002381665.1 469890 D 585054 CDS YP_002381666.1 218547875 7122161 470699..471046 1 NC_011740.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 471046 rplS 7122161 rplS Escherichia fergusonii ATCC 35469 50S ribosomal protein L19 YP_002381666.1 470699 D 585054 CDS YP_002381667.1 218547876 7121106 complement(471249..471623) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 471623 7121106 EFER_0467 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381667.1 471249 R 585054 CDS YP_002381668.1 218547877 7123345 471839..472909 1 NC_011740.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 472909 aroF 7123345 aroF Escherichia fergusonii ATCC 35469 phospho-2-dehydro-3-deoxyheptonate aldolase YP_002381668.1 471839 D 585054 CDS YP_002381669.1 218547878 7120548 472920..474041 1 NC_011740.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase 474041 tyrA 7120548 tyrA Escherichia fergusonii ATCC 35469 bifunctional chorismate mutase/prephenate dehydrogenase YP_002381669.1 472920 D 585054 CDS YP_002381670.1 218547879 7122612 complement(474084..475244) 1 NC_011740.1 catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; bifunctional chorismate mutase/prephenate dehydratase 475244 pheA 7122612 pheA Escherichia fergusonii ATCC 35469 bifunctional chorismate mutase/prephenate dehydratase YP_002381670.1 474084 R 585054 CDS YP_002381672.1 218547881 7122592 complement(475495..475839) 1 NC_011740.1 associated with 30S ribosomal subunit; interferes with translation elongation; translation inhibitor protein RaiA 475839 yfiA 7122592 yfiA Escherichia fergusonii ATCC 35469 translation inhibitor protein RaiA YP_002381672.1 475495 R 585054 CDS YP_002381673.1 218547882 7123325 complement(476107..476844) 1 NC_011740.1 with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline; outer membrane protein assembly complex subunit YfiO 476844 yfiO 7123325 yfiO Escherichia fergusonii ATCC 35469 outer membrane protein assembly complex subunit YfiO YP_002381673.1 476107 R 585054 CDS YP_002381674.1 218547883 7121477 476979..477959 1 NC_011740.1 responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D 477959 rluD 7121477 rluD Escherichia fergusonii ATCC 35469 23S rRNA pseudouridine synthase D YP_002381674.1 476979 D 585054 CDS YP_002381675.1 218547884 7123317 477956..478687 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1906060, 2066329; hypothetical protein 478687 yfiH 7123317 yfiH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381675.1 477956 D 585054 CDS YP_002381676.1 218547885 7121179 478817..481390 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14550559, 14640692, 91294166, 93015925, 93388583, 99428468; Product type f : factor; protein disaggregation chaperone 481390 clpB 7121179 clpB Escherichia fergusonii ATCC 35469 protein disaggregation chaperone YP_002381676.1 478817 D 585054 CDS YP_002381677.1 218547886 7120510 487175..488473 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91219460, 1709493, 2053984, 2118499, 2190187, 8419306; Product type t : transporter; alpha-ketoglutarate transporter 488473 kgtP 7120510 kgtP Escherichia fergusonii ATCC 35469 alpha-ketoglutarate transporter YP_002381677.1 487175 D 585054 CDS YP_002381678.1 218547887 7120814 complement(488470..488742) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 488742 yfiM 7120814 yfiM Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381678.1 488470 R 585054 CDS YP_002381679.1 218547888 7121476 complement(488839..490194) 1 NC_011740.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase 490194 pssA 7121476 pssA Escherichia fergusonii ATCC 35469 phosphatidylserine synthase YP_002381679.1 488839 R 585054 CDS YP_002381680.1 218547889 7122307 complement(490308..492968) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; acyl-CoA synthetase NAD(P)-binding subunit/ATP-binding subunit 492968 yfiQ 7122307 yfiQ Escherichia fergusonii ATCC 35469 acyl-CoA synthetase NAD(P)-binding subunit/ATP-binding subunit YP_002381680.1 490308 R 585054 CDS YP_002381681.1 218547890 7121479 complement(493000..493698) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 493698 yfiP 7121479 yfiP Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381681.1 493000 R 585054 CDS YP_002381682.1 218547891 7121478 complement(493767..494186) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12952960, 9388228, 99175138, 10644706; Product type c : carrier; thioredoxin 2 494186 trxC 7121478 trxC Escherichia fergusonii ATCC 35469 thioredoxin 2 YP_002381682.1 493767 R 585054 CDS YP_002381683.1 218547892 7122173 494200..494403 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 494403 7122173 EFER_0492 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381683.1 494200 D 585054 CDS YP_002381684.1 218547893 7121589 494393..495430 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; methyltransferase 495430 yfiF 7121589 yfiF Escherichia fergusonii ATCC 35469 methyltransferase YP_002381684.1 494393 D 585054 CDS YP_002381685.1 218547894 7121474 complement(495478..496167) 1 NC_011740.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 496167 ung 7121474 ung Escherichia fergusonii ATCC 35469 uracil-DNA glycosylase YP_002381685.1 495478 R 585054 CDS YP_002381686.1 218547895 7122639 496472..496855 1 NC_011740.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA 496855 yfiD 7122639 yfiD Escherichia fergusonii ATCC 35469 autonomous glycyl radical cofactor GrcA YP_002381686.1 496472 D 585054 CDS YP_002381687.1 218547896 7121473 complement(497334..498668) 1 NC_011740.1 facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB 498668 srmB 7121473 srmB Escherichia fergusonii ATCC 35469 ATP-dependent RNA helicase SrmB YP_002381687.1 497334 R 585054 CDS YP_002381688.1 218547897 7121940 498800..499537 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; S-adenosyl-L-methionine-dependent methyltransferase 499537 yfiC 7121940 yfiC Escherichia fergusonii ATCC 35469 S-adenosyl-L-methionine-dependent methyltransferase YP_002381688.1 498800 D 585054 CDS YP_002381689.1 218547898 7123872 complement(499522..501144) 1 NC_011740.1 catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase 501144 nadB 7123872 nadB Escherichia fergusonii ATCC 35469 L-aspartate oxidase YP_002381689.1 499522 R 585054 CDS YP_002381690.1 218547899 7120658 501552..502127 1 NC_011740.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE 502127 rpoE 7120658 rpoE Escherichia fergusonii ATCC 35469 RNA polymerase sigma factor RpoE YP_002381690.1 501552 D 585054 CDS YP_002381691.1 218547900 7121122 502160..502810 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9159522, 97303092, 99431977, 7768826; Product type f : factor; anti-RNA polymerase sigma factor SigE 502810 rseA 7121122 rseA Escherichia fergusonii ATCC 35469 anti-RNA polymerase sigma factor SigE YP_002381691.1 502160 D 585054 CDS YP_002381692.1 218547901 7121145 502810..503766 1 NC_011740.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE 503766 rseB 7121145 rseB Escherichia fergusonii ATCC 35469 periplasmic negative regulator of sigmaE YP_002381692.1 502810 D 585054 CDS YP_002381693.1 218547902 7121146 503763..504242 1 NC_011740.1 involved in the reduction of the SoxR iron-sulfur cluster; SoxR reducing system protein RseC 504242 rseC 7121146 rseC Escherichia fergusonii ATCC 35469 SoxR reducing system protein RseC YP_002381693.1 503763 D 585054 CDS YP_002381694.1 218547903 7121147 504440..506239 1 NC_011740.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 506239 lepA 7121147 lepA Escherichia fergusonii ATCC 35469 GTP-binding protein LepA YP_002381694.1 504440 D 585054 CDS YP_002381695.1 218547904 7120822 506255..507229 1 NC_011740.1 catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; signal peptidase I 507229 lepB 7120822 lepB Escherichia fergusonii ATCC 35469 signal peptidase I YP_002381695.1 506255 D 585054 CDS YP_002381696.1 218547905 7120823 507502..508182 1 NC_011740.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 508182 rnc 7120823 rnc Escherichia fergusonii ATCC 35469 ribonuclease III YP_002381696.1 507502 D 585054 CDS YP_002381697.1 218547906 7121423 508179..509084 1 NC_011740.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 509084 era 7121423 era Escherichia fergusonii ATCC 35469 GTP-binding protein Era YP_002381697.1 508179 D 585054 CDS YP_002381698.1 218547907 7122960 509096..509824 1 NC_011740.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 509824 recO 7122960 recO Escherichia fergusonii ATCC 35469 DNA repair protein RecO YP_002381698.1 509096 D 585054 CDS YP_002381699.1 218547908 7121383 509836..510567 1 NC_011740.1 involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 510567 pdxJ 7121383 pdxJ Escherichia fergusonii ATCC 35469 pyridoxine 5'-phosphate synthase YP_002381699.1 509836 D 585054 CDS YP_002381700.1 218547909 7124064 510567..510947 1 NC_011740.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 510947 acpS 7124064 acpS Escherichia fergusonii ATCC 35469 4'-phosphopantetheinyl transferase YP_002381700.1 510567 D 585054 CDS YP_002381701.1 218547910 7123281 511206..511370 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 511370 7123281 EFER_0512 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381701.1 511206 D 585054 CDS YP_002381702.1 218547911 7121590 complement(511640..511900) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 8765743, 8880900; Product type c : carrier; ferredoxin 511900 yfhL 7121590 yfhL Escherichia fergusonii ATCC 35469 ferredoxin YP_002381702.1 511640 R 585054 CDS YP_002381703.1 218547912 7121468 complement(511956..512804) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator 512804 yfhH 7121468 yfhH Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YP_002381703.1 511956 R 585054 CDS YP_002381704.1 218547913 7121465 513013..513648 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 513648 yfhB 7121465 yfhB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381704.1 513013 D 585054 CDS YP_002381705.1 218547914 7123871 513673..514209 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12110595; Product type e : enzyme; tRNA-specific adenosine deaminase 514209 tadA 7123871 tadA Escherichia fergusonii ATCC 35469 tRNA-specific adenosine deaminase YP_002381705.1 513673 D 585054 CDS YP_002381706.1 218547915 7121970 complement(514206..515624) 1 NC_011740.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; transglycosylase 515624 yfhD 7121970 yfhD Escherichia fergusonii ATCC 35469 transglycosylase YP_002381706.1 514206 R 585054 CDS YP_002381707.1 218547916 7121463 516020..519907 1 NC_011740.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 519907 purL 7121463 purL Escherichia fergusonii ATCC 35469 phosphoribosylformylglycinamidine synthase YP_002381707.1 516020 D 585054 CDS YP_002381708.1 218547917 7122133 520482..521909 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; sensory kinase in two-component system 521909 yfhK 7122133 yfhK Escherichia fergusonii ATCC 35469 sensory kinase in two-component system YP_002381708.1 520482 D 585054 CDS YP_002381709.1 218547918 7121467 522074..522787 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 522787 yfhG 7121467 yfhG Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381709.1 522074 D 585054 CDS YP_002381710.1 218547919 7121464 522777..524111 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8226691, 8412694; Product type pr : regulator; two component system DNA-binding response regulator 524111 yfhA 7121464 yfhA Escherichia fergusonii ATCC 35469 two component system DNA-binding response regulator YP_002381710.1 522777 D 585054 CDS YP_002381711.1 218547920 7121462 524172..524510 1 NC_011740.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; nitrogen regulatory protein P-II 1 524510 glnB 7121462 glnB Escherichia fergusonii ATCC 35469 nitrogen regulatory protein P-II 1 YP_002381711.1 524172 D 585054 CDS YP_002381712.1 218547921 7120194 524761..525405 1 NC_011740.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 525405 adk 7120194 adk Escherichia fergusonii ATCC 35469 adenylate kinase YP_002381712.1 524761 D 585054 CDS YP_002381713.1 218547922 7122277 525537..526499 1 NC_011740.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 526499 hemH 7122277 hemH Escherichia fergusonii ATCC 35469 ferrochelatase YP_002381713.1 525537 D 585054 CDS YP_002381714.1 218547923 7122184 complement(526474..527490) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9401025, 98244813, 2051480, 7721718; Product type e : enzyme; acetyl esterase 527490 aes 7122184 aes Escherichia fergusonii ATCC 35469 acetyl esterase YP_002381714.1 526474 R 585054 CDS YP_002381715.1 218547924 7122280 527594..528898 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90155203, 95238302, 2051480; Product type e : enzyme; inosine/guanosine kinase 528898 gsk 7122280 gsk Escherichia fergusonii ATCC 35469 inosine/guanosine kinase YP_002381715.1 527594 D 585054 CDS YP_002381716.1 218547925 7120620 529054..529311 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 529311 7120620 EFER_0528 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381716.1 529054 D 585054 CDS YP_002381717.1 218547926 7121591 529382..529843 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 529843 7121591 EFER_0529 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381717.1 529382 D 585054 CDS YP_002381718.1 218547927 7121592 complement(529868..531544) 1 NC_011740.1 YbaL; member of the CPA-2 family of antiporters; uncharacterized protein; cation:proton antiport protein 531544 ybaL 7121592 ybaL Escherichia fergusonii ATCC 35469 cation:proton antiport protein YP_002381718.1 529868 R 585054 CDS YP_002381719.1 218547928 7121066 complement(531778..532986) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21450803, 97074653, 8917080; Product type t : transporter; fosmidomycin efflux systemprotein 532986 fsr 7121066 fsr Escherichia fergusonii ATCC 35469 fosmidomycin efflux systemprotein YP_002381719.1 531778 R 585054 CDS YP_002381720.1 218547929 7123025 533161..534813 1 NC_011740.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic 534813 ushA 7123025 ushA Escherichia fergusonii ATCC 35469 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic YP_002381720.1 533161 D 585054 CDS YP_002381721.1 218547930 7121172 complement(534851..535354) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 535354 7121172 EFER_0533 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381721.1 534851 R 585054 CDS YP_002381722.1 218547931 7121593 complement(535351..536151) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 536151 7121593 EFER_0534 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381722.1 535351 R 585054 CDS YP_002381723.1 218547932 7121594 complement(536175..536654) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 536654 ybaK 7121594 ybaK Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381723.1 536175 R 585054 CDS YP_002381724.1 218547933 7121941 complement(536858..537652) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 537652 ybaP 7121941 ybaP Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381724.1 536858 R 585054 CDS YP_002381725.1 218547934 7121069 537785..538087 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; RelE/ParE family protein, cytotoxic translational repressor of toxin-antitoxin stability system 538087 7121069 EFER_0537 Escherichia fergusonii ATCC 35469 RelE/ParE family protein, cytotoxic translational repressor of toxin-antitoxin stability system YP_002381725.1 537785 D 585054 CDS YP_002381726.1 218547935 7123895 538123..538464 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator 538464 ybaQ 7123895 ybaQ Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YP_002381726.1 538123 D 585054 CDS YP_002381727.1 218547936 7123262 complement(538578..541082) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12351646, 20105527, 11167016, 11500054, 9868784; Product type t : transporter; copper exporting ATPase 541082 copA 7123262 copA Escherichia fergusonii ATCC 35469 copper exporting ATPase YP_002381727.1 538578 R 585054 CDS YP_002381728.1 218547937 7122793 541389..542678 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; nitrogen-containing metabolite transporter 542678 ybaT 7122793 ybaT Escherichia fergusonii ATCC 35469 nitrogen-containing metabolite transporter YP_002381728.1 541389 D 585054 CDS YP_002381729.1 218547938 7121071 543025..544380 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17220313, 15522082, 2905265; Product type t : transporter; outer membrane transport protein, type I secretion 544380 siiCA 7121071 siiCA Escherichia fergusonii ATCC 35469 outer membrane transport protein, type I secretion YP_002381729.1 543025 D 585054 CDS YP_002381730.1 218547939 7121784 544489..566157 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17220313, 15522082, 2905265; Product type f : factor; adhesin for cattle intestine colonization 566157 siiEA 7121784 siiEA Escherichia fergusonii ATCC 35469 adhesin for cattle intestine colonization YP_002381730.1 544489 D 585054 CDS YP_002381731.1 218547940 7121786 566161..568323 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17220313, 15522082, 2905265, 2185213; Product type t : transporter; type I secretion membrane protein 568323 siiBA 7121786 siiBA Escherichia fergusonii ATCC 35469 type I secretion membrane protein YP_002381731.1 566161 D 585054 CDS YP_002381732.1 218547941 7123922 568320..569495 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17220313, 15522082, 2905265; Product type t : transporter; RtxD/HlyD/CyaD protein of type I secretion system 569495 siiDA 7123922 siiDA Escherichia fergusonii ATCC 35469 RtxD/HlyD/CyaD protein of type I secretion system YP_002381732.1 568320 D 585054 CDS YP_002381733.1 218547942 7121785 569492..569899 1 NC_011740.1 activator of copper-responsive regulon genes; DNA-binding transcriptional regulator CueR 569899 cueR 7121785 cueR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator CueR YP_002381733.1 569492 D 585054 CDS YP_002381734.1 218547943 7122827 complement(569900..570358) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 570358 ybbJ 7122827 ybbJ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381734.1 569900 R 585054 CDS YP_002381735.1 218547944 7121077 complement(570355..571272) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; protease, membrane anchored 571272 ybbK 7121077 ybbK Escherichia fergusonii ATCC 35469 protease, membrane anchored YP_002381735.1 570355 R 585054 CDS YP_002381736.1 218547945 7121078 571418..572095 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter ATP-binding protein 572095 ybbL 7121078 ybbL Escherichia fergusonii ATCC 35469 ABC transporter ATP-binding protein YP_002381736.1 571418 D 585054 CDS YP_002381737.1 218547946 7121079 572082..572861 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; ABC transporter permease 572861 ybbM 7121079 ybbM Escherichia fergusonii ATCC 35469 ABC transporter permease YP_002381737.1 572082 D 585054 CDS YP_002381738.1 218547947 7123264 complement(573041..573895) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; thioredoxin domain-containing protein 573895 ybbN 7123264 ybbN Escherichia fergusonii ATCC 35469 thioredoxin domain-containing protein YP_002381738.1 573041 R 585054 CDS YP_002381739.1 218547948 7121080 complement(573956..574765) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; short chain dehydrogenase 574765 ybbO 7121080 ybbO Escherichia fergusonii ATCC 35469 short chain dehydrogenase YP_002381739.1 573956 R 585054 CDS YP_002381740.1 218547949 7121081 complement(574755..575381) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91270121, 91324311, 93163029, 93252782, 94179121, 99353977, 1864840, 8432696, 8098033; Product type e : enzyme; multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 575381 tesA 7121081 tesA Escherichia fergusonii ATCC 35469 multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 YP_002381740.1 574755 R 585054 CDS YP_002381741.1 218547950 7121985 575349..576035 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter ATP-binding protein 576035 ybbA 7121985 ybbA Escherichia fergusonii ATCC 35469 ABC transporter ATP-binding protein YP_002381741.1 575349 D 585054 CDS YP_002381742.1 218547951 7121075 576032..578446 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type t : transporter; ABC transporter permease 578446 ybbP 7121075 ybbP Escherichia fergusonii ATCC 35469 ABC transporter permease YP_002381742.1 576032 D 585054 CDS YP_002381743.1 218547952 7123265 578683..578898 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 578898 7123265 EFER_0555 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381743.1 578683 D 585054 CDS YP_002381744.1 218547953 7121595 578996..579202 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 579202 7121595 EFER_0556 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381744.1 578996 D 585054 CDS YP_002381745.1 218547954 7121596 579671..579829 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 579829 7121596 EFER_0557 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381745.1 579671 D 585054 CDS YP_002381746.1 218547955 7123346 580256..580402 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 580402 7123346 EFER_0558 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381746.1 580256 D 585054 CDS YP_002381747.1 218547956 7121597 complement(580595..581689) 1 NC_011740.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA; tRNA 2-selenouridine synthase 581689 ybbB 7121597 ybbB Escherichia fergusonii ATCC 35469 tRNA 2-selenouridine synthase YP_002381747.1 580595 R 585054 CDS YP_002381748.1 218547957 7121076 581968..582621 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 582621 ylbF 7121076 ylbF Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381748.1 581968 D 585054 CDS YP_002381749.1 218547958 7122043 582618..583511 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2464576, 2644189, 7920643, 7940673, 7984428; Product type pe : enzyme; carbamate kinase 583511 ybcF 7122043 ybcF Escherichia fergusonii ATCC 35469 carbamate kinase YP_002381749.1 582618 D 585054 CDS YP_002381750.1 218547959 7122324 complement(584719..585228) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10074353, 8117684, 89123018, 89123019, 92287929, 10574791; Product type e : enzyme; N5-carboxyaminoimidazole ribonucleotide mutase 585228 purE 7122324 purE Escherichia fergusonii ATCC 35469 N5-carboxyaminoimidazole ribonucleotide mutase YP_002381750.1 584719 R 585054 CDS YP_002381751.1 218547960 7122321 complement(585324..585653) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 585653 7122321 EFER_0565 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381751.1 585324 R 585054 CDS YP_002381752.1 218547961 7121598 complement(585764..586486) 1 NC_011740.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase 586486 lpxH 7121598 lpxH Escherichia fergusonii ATCC 35469 UDP-2,3-diacylglucosamine hydrolase YP_002381752.1 585764 R 585054 CDS YP_002381753.1 218547962 7123282 complement(586489..586983) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90272647, 91175755, 1606970, 1864365, 8601841, 9298646, 9600841; Product type e : enzyme; peptidyl-prolyl cis-trans isomerase B 586983 ppiB 7123282 ppiB Escherichia fergusonii ATCC 35469 peptidyl-prolyl cis-trans isomerase B YP_002381753.1 586489 R 585054 CDS YP_002381754.1 218547963 7123106 587157..588542 1 NC_011740.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 588542 cysS 7123106 cysS Escherichia fergusonii ATCC 35469 cysteinyl-tRNA synthetase YP_002381754.1 587157 D 585054 CDS YP_002381755.1 218547964 7122856 complement(588578..589099) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 589099 ybcI 7122856 ybcI Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381755.1 588578 R 585054 CDS YP_002381756.1 218547965 7121084 complement(589207..589419) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12837795, 1748668, 7567469; Product type pr : regulator; hypothetical protein 589419 ybcJ 7121084 ybcJ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381756.1 589207 R 585054 CDS YP_002381757.1 218547966 7121085 complement(589421..590287) 1 NC_011740.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 590287 folD 7121085 folD Escherichia fergusonii ATCC 35469 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_002381757.1 589421 R 585054 CDS YP_002381758.1 218547967 7120027 complement(590641..591804) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 90036709, 2183007; Product type pe : enzyme; integrase; DLP12 prophage 591804 intD 7120027 intD Escherichia fergusonii ATCC 35469 integrase; DLP12 prophage YP_002381758.1 590641 R 585054 CDS YP_002381759.1 218547968 7120754 complement(592031..592336) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 592336 yfdT 7120754 yfdT Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381759.1 592031 R 585054 CDS YP_002381760.1 218547969 7119838 complement(592336..592698) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 592698 yfdS 7119838 yfdS Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381760.1 592336 R 585054 CDS YP_002381761.1 218547970 7119837 complement(592689..593225) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 593225 yfdR 7119837 yfdR Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381761.1 592689 R 585054 CDS YP_002381762.1 218547971 7119835 complement(593353..594177) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 594177 yfdQ 7119835 yfdQ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381762.1 593353 R 585054 CDS YP_002381763.1 218547972 7123058 complement(594243..594923) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 594923 7123058 EFER_0577 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381763.1 594243 R 585054 CDS YP_002381764.1 218547973 7123347 594417..594902 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 594902 7123347 EFER_0578 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381764.1 594417 D 585054 CDS YP_002381765.1 218547974 7121599 595074..595508 1 NC_011740.1 Evidence 6 : Doubtful CDS; Product type h : extrachromosomal origin; hypothetical protein 595508 7121599 EFER_0579 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381765.1 595074 D 585054 CDS YP_002381766.1 218547975 7121600 complement(595480..595701) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 595701 7121600 EFER_0580 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381766.1 595480 R 585054 CDS YP_002381767.1 218547976 7121601 595922..596842 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 596842 7121601 EFER_0581 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381767.1 595922 D 585054 CDS YP_002381768.1 218547977 7121602 complement(596825..597511) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; Cro/CI family transcriptional regulator 597511 7121602 EFER_0582 Escherichia fergusonii ATCC 35469 Cro/CI family transcriptional regulator YP_002381768.1 596825 R 585054 CDS YP_002381769.1 218547978 7121603 597647..597895 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 597895 7121603 EFER_0583 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381769.1 597647 D 585054 CDS YP_002381770.1 218547979 7121604 597813..598469 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; nucleic acid-binding protein; e14 prophage 598469 ymfL 7121604 ymfL Escherichia fergusonii ATCC 35469 nucleic acid-binding protein; e14 prophage YP_002381770.1 597813 D 585054 CDS YP_002381771.1 218547980 7122056 598466..598804 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 598804 ymfM 7122056 ymfM Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381771.1 598466 D 585054 CDS YP_002381772.1 218547981 7122058 598814..599755 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; phage replication protein O 599755 7122058 EFER_0587 Escherichia fergusonii ATCC 35469 phage replication protein O YP_002381772.1 598814 D 585054 CDS YP_002381773.1 218547982 7123896 599752..600246 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 600246 yfdN 7123896 yfdN Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381773.1 599752 D 585054 CDS YP_002381774.1 218547983 7119832 600213..600899 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; phage AdoMet-dependent methyltransferase 600899 7119832 EFER_0589 Escherichia fergusonii ATCC 35469 phage AdoMet-dependent methyltransferase YP_002381774.1 600213 D 585054 CDS YP_002381775.1 218547984 7121605 600896..601222 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; LexA repressor 601222 7121605 EFER_0590 Escherichia fergusonii ATCC 35469 LexA repressor YP_002381775.1 600896 D 585054 CDS YP_002381776.1 218547985 7121606 601219..601608 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Crossover junction endodeoxyribonuclease 601608 rusA 7121606 rusA Escherichia fergusonii ATCC 35469 Crossover junction endodeoxyribonuclease YP_002381776.1 601219 D 585054 CDS YP_002381777.1 218547986 7121165 601628..602425 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 602425 7121165 EFER_0592 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381777.1 601628 D 585054 CDS YP_002381778.1 218547987 7121607 602427..603422 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 603422 7121607 EFER_0593 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381778.1 602427 D 585054 CDS YP_002381779.1 218547988 7121608 603425..603802 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; antitermination protein Q from phage origin 603802 7121608 EFER_0594 Escherichia fergusonii ATCC 35469 antitermination protein Q from phage origin YP_002381779.1 603425 D 585054 CDS YP_002381780.1 218547989 7121609 complement(603853..604599) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 604599 7121609 EFER_0595 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381780.1 603853 R 585054 CDS YP_002381781.1 218547990 7121610 604866..605192 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2998005; Product type h : extrachromosomal origin; Holin 605192 S 7121610 S Escherichia fergusonii ATCC 35469 Holin YP_002381781.1 604866 D 585054 CDS YP_002381782.1 218547991 7123824 605196..605672 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; lysozyme 605672 r 7123824 r Escherichia fergusonii ATCC 35469 lysozyme YP_002381782.1 605196 D 585054 CDS YP_002381783.1 218547992 7122343 605656..606048 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; Rz lytic protein from phage origin, coiled-coil 606048 7122343 EFER_0598 Escherichia fergusonii ATCC 35469 Rz lytic protein from phage origin, coiled-coil YP_002381783.1 605656 D 585054 CDS YP_002381784.1 218547993 7121611 606562..607008 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 607008 7121611 EFER_0599 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381784.1 606562 D 585054 CDS YP_002381785.1 218547994 7121612 607136..607486 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; endonuclease 607486 7121612 EFER_0600 Escherichia fergusonii ATCC 35469 endonuclease YP_002381785.1 607136 D 585054 CDS YP_002381786.1 218547995 7121613 607603..608106 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; phage terminase small subunit 608106 7121613 EFER_0601 Escherichia fergusonii ATCC 35469 phage terminase small subunit YP_002381786.1 607603 D 585054 CDS YP_002381787.1 218547996 7123897 608103..609836 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; phage terminase 609836 7123897 EFER_0602 Escherichia fergusonii ATCC 35469 phage terminase YP_002381787.1 608103 D 585054 CDS YP_002381788.1 218547997 7121614 609848..610030 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 610030 ymfR 7121614 ymfR Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381788.1 609848 D 585054 CDS YP_002381789.1 218547998 7121688 610030..611271 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; phage portal protein 611271 7121688 EFER_0604 Escherichia fergusonii ATCC 35469 phage portal protein YP_002381789.1 610030 D 585054 CDS YP_002381790.1 218547999 7123348 611213..611899 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; phage pro-head protease 611899 7123348 EFER_0605 Escherichia fergusonii ATCC 35469 phage pro-head protease YP_002381790.1 611213 D 585054 CDS YP_002381791.1 218548000 7121615 611914..613119 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; major capsid protein 613119 7121615 EFER_0606 Escherichia fergusonii ATCC 35469 major capsid protein YP_002381791.1 611914 D 585054 CDS YP_002381792.1 218548001 7121616 613169..613369 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 613369 7121616 EFER_0607 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381792.1 613169 D 585054 CDS YP_002381793.1 218548002 7123349 613372..613695 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 613695 7123349 EFER_0608 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381793.1 613372 D 585054 CDS YP_002381794.1 218548003 7121617 613692..614102 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; phage head-tail adaptor 614102 7121617 EFER_0609 Escherichia fergusonii ATCC 35469 phage head-tail adaptor YP_002381794.1 613692 D 585054 CDS YP_002381795.1 218548004 7121618 614077..614583 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 614583 7121618 EFER_0610 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381795.1 614077 D 585054 CDS YP_002381796.1 218548005 7123350 614580..615140 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 615140 7123350 EFER_0611 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381796.1 614580 D 585054 CDS YP_002381797.1 218548006 7121619 615149..615319 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 615319 7121619 EFER_0612 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381797.1 615149 D 585054 CDS YP_002381798.1 218548007 7121620 615303..616799 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; tail sheath protein 616799 7121620 EFER_0613 Escherichia fergusonii ATCC 35469 tail sheath protein YP_002381798.1 615303 D 585054 CDS YP_002381799.1 218548008 7121621 616799..617155 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; phage tail protein 617155 7121621 EFER_0614 Escherichia fergusonii ATCC 35469 phage tail protein YP_002381799.1 616799 D 585054 CDS YP_002381800.1 218548009 7123898 617155..617424 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 617424 7123898 EFER_0615 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381800.1 617155 D 585054 CDS YP_002381801.1 218548010 7121622 617566..619398 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; phage tail tape measure protein 619398 7121622 EFER_0616 Escherichia fergusonii ATCC 35469 phage tail tape measure protein YP_002381801.1 617566 D 585054 CDS YP_002381802.1 218548011 7121623 619480..619992 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 619992 7121623 EFER_0617 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381802.1 619480 D 585054 CDS YP_002381803.1 218548012 7123899 620083..621411 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; tail/DNA circulation protein 621411 7123899 EFER_0618 Escherichia fergusonii ATCC 35469 tail/DNA circulation protein YP_002381803.1 620083 D 585054 CDS YP_002381804.1 218548013 7121624 621408..622487 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; tail protein 622487 7121624 EFER_0619 Escherichia fergusonii ATCC 35469 tail protein YP_002381804.1 621408 D 585054 CDS YP_002381805.1 218548014 7123351 622487..623035 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; baseplate assembly phage protein 623035 7123351 EFER_0620 Escherichia fergusonii ATCC 35469 baseplate assembly phage protein YP_002381805.1 622487 D 585054 CDS YP_002381806.1 218548015 7121625 623032..623460 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; tail protein 623460 7121625 EFER_0621 Escherichia fergusonii ATCC 35469 tail protein YP_002381806.1 623032 D 585054 CDS YP_002381807.1 218548016 7120144 623447..624505 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; baseplate J-like phage protein 624505 7120144 EFER_0622 Escherichia fergusonii ATCC 35469 baseplate J-like phage protein YP_002381807.1 623447 D 585054 CDS YP_002381808.1 218548017 7120206 624496..625080 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 625080 ymfQ 7120206 ymfQ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381808.1 624496 D 585054 CDS YP_002381809.1 218548018 7123928 625084..626013 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 626013 7123928 EFER_0624 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381809.1 625084 D 585054 CDS YP_002381810.1 218548019 7120207 625989..626549 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 626549 7120207 EFER_0625 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381810.1 625989 D 585054 CDS YP_002381811.1 218548020 7120208 complement(626947..628074) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 628074 7120208 EFER_0626 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381811.1 626947 R 585054 CDS YP_002381812.1 218548021 7120209 629487..629636 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 629636 7120209 EFER_0627 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381812.1 629487 D 585054 CDS YP_002381813.1 218548022 7120210 complement(629928..630860) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12878731, 13129938, 9689094; Product type h : extrachromosomal origin; bactoprenol glucosyl transferase; CPS-53 (KpLE1) prophage 630860 yfdH 7120210 yfdH Escherichia fergusonii ATCC 35469 bactoprenol glucosyl transferase; CPS-53 (KpLE1) prophage YP_002381813.1 629928 R 585054 CDS YP_002381814.1 218548023 7119831 complement(630857..631219) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12878731, 13129938, 9689094; Product type h : extrachromosomal origin; bactoprenol-linked glucose translocase (flippase) ; CPS-53 (KpLE1) prophage 631219 yfdG 7119831 yfdG Escherichia fergusonii ATCC 35469 bactoprenol-linked glucose translocase (flippase) ; CPS-53 (KpLE1) prophage YP_002381814.1 630857 R 585054 CDS YP_002381815.1 218548024 7119830 complement(631591..632781) 1 NC_011740.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase 632781 hmp 7119830 hmp Escherichia fergusonii ATCC 35469 nitric oxide dioxygenase YP_002381815.1 631591 R 585054 CDS YP_002381816.1 218548025 7123999 633109..634362 1 NC_011740.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 634362 glyA 7123999 glyA Escherichia fergusonii ATCC 35469 serine hydroxymethyltransferase YP_002381816.1 633109 D 585054 CDS YP_002381817.1 218548026 7120589 complement(634411..634905) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 634905 yphA 7120589 yphA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381817.1 634411 R 585054 CDS YP_002381818.1 218548027 7119717 635062..636201 1 NC_011740.1 transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; 3-phenylpropionic acid transporter 636201 hcaT 7119717 hcaT Escherichia fergusonii ATCC 35469 3-phenylpropionic acid transporter YP_002381818.1 635062 D 585054 CDS YP_002381819.1 218548028 7123192 complement(636193..637473) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type ph : phenotype; stationary phase inducible protein CsiE 637473 csiE 7123192 csiE Escherichia fergusonii ATCC 35469 stationary phase inducible protein CsiE YP_002381819.1 636193 R 585054 CDS YP_002381820.1 218548029 7122815 complement(637669..638520) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; peptidase 638520 yfhR 7122815 yfhR Escherichia fergusonii ATCC 35469 peptidase YP_002381820.1 637669 R 585054 CDS YP_002381821.1 218548030 7121471 complement(638654..639457) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6389495, 90202735, 95095968, 10747806, 2138605, 8002619; Product type e : enzyme; inositol monophosphatase 639457 suhB 7121471 suhB Escherichia fergusonii ATCC 35469 inositol monophosphatase YP_002381821.1 638654 R 585054 CDS YP_002381822.1 218548031 7121965 639576..640316 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10393315; Product type pe : enzyme; methyltransferase 640316 yfhQ 7121965 yfhQ Escherichia fergusonii ATCC 35469 methyltransferase YP_002381822.1 639576 D 585054 CDS YP_002381823.1 218548032 7121470 640586..641074 1 NC_011740.1 regulates the expression of the iscRSUA operon; DNA-binding transcriptional regulator IscR 641074 iscR 7121470 iscR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator IscR YP_002381823.1 640586 D 585054 CDS YP_002381824.1 218548033 7120756 641315..642529 1 NC_011740.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 642529 iscS 7120756 iscS Escherichia fergusonii ATCC 35469 cysteine desulfurase YP_002381824.1 641315 D 585054 CDS YP_002381825.1 218548034 7120757 642557..642943 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10393315, 11994302, 15153099; Product type f : factor; scaffold protein 642943 iscU 7120757 iscU Escherichia fergusonii ATCC 35469 scaffold protein YP_002381825.1 642557 D 585054 CDS YP_002381826.1 218548035 7120758 642960..643283 1 NC_011740.1 forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; iron-sulfur cluster assembly protein 643283 iscA 7120758 iscA Escherichia fergusonii ATCC 35469 iron-sulfur cluster assembly protein YP_002381826.1 642960 D 585054 CDS YP_002381827.1 218548036 7123216 643379..643894 1 NC_011740.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB 643894 hscB 7123216 hscB Escherichia fergusonii ATCC 35469 co-chaperone HscB YP_002381827.1 643379 D 585054 CDS YP_002381828.1 218548037 7123445 643911..645761 1 NC_011740.1 involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA 645761 hscA 7123445 hscA Escherichia fergusonii ATCC 35469 chaperone protein HscA YP_002381828.1 643911 D 585054 CDS YP_002381829.1 218548038 7122222 645763..646098 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10393315, 20013001, 92283811, 94181532, 11551196, 1317854, 4375562, 8300516; Product type c : carrier; [2Fe-2S] ferredoxin 646098 fdx 7122222 fdx Escherichia fergusonii ATCC 35469 [2Fe-2S] ferredoxin YP_002381829.1 645763 D 585054 CDS YP_002381830.1 218548039 7120002 646110..646310 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10393315; Product type pf : factor; hypothetical protein 646310 yfhJ 7120002 yfhJ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381830.1 646110 D 585054 CDS YP_002381831.1 218548040 7121466 646488..647771 1 NC_011740.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase B 647771 pepB 7121466 pepB Escherichia fergusonii ATCC 35469 aminopeptidase B YP_002381831.1 646488 D 585054 CDS YP_002381832.1 218548041 7122575 647890..648666 1 NC_011740.1 enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I; enhanced serine sensitivity protein SseB 648666 sseB 7122575 sseB Escherichia fergusonii ATCC 35469 enhanced serine sensitivity protein SseB YP_002381832.1 647890 D 585054 CDS YP_002381833.1 218548042 7120755 complement(649431..650276) 1 NC_011740.1 catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; 3-mercaptopyruvate sulfurtransferase 650276 sseA 7120755 sseA Escherichia fergusonii ATCC 35469 3-mercaptopyruvate sulfurtransferase YP_002381833.1 649431 R 585054 CDS YP_002381834.1 218548043 7123399 650482..655461 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 655461 yfhM 7123399 yfhM Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381834.1 650482 D 585054 CDS YP_002381835.1 218548044 7121469 655462..657774 1 NC_011740.1 penicillin-insensitive transglycosylase/transpeptidase; penicillin-binding protein 1C 657774 pbpC 7121469 pbpC Escherichia fergusonii ATCC 35469 penicillin-binding protein 1C YP_002381835.1 655462 D 585054 CDS YP_002381836.1 218548045 7122558 657922..658353 1 NC_011740.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 658353 ndk 7122558 ndk Escherichia fergusonii ATCC 35469 nucleoside diphosphate kinase YP_002381836.1 657922 D 585054 CDS YP_002381837.1 218548046 7120683 658503..659657 1 NC_011740.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 659657 yfgB 7120683 yfgB Escherichia fergusonii ATCC 35469 ribosomal RNA large subunit methyltransferase N YP_002381837.1 658503 D 585054 CDS YP_002381838.1 218548047 7121457 659948..660964 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; cytoskeletal protein RodZ 660964 yfgA 7121457 yfgA Escherichia fergusonii ATCC 35469 cytoskeletal protein RodZ YP_002381838.1 659948 D 585054 CDS YP_002381839.1 218548048 7121456 660991..662109 1 NC_011740.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 662109 ispG 7121456 ispG Escherichia fergusonii ATCC 35469 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_002381839.1 660991 D 585054 CDS YP_002381840.1 218548049 7120794 662220..663509 1 NC_011740.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 663509 hisS 7120794 hisS Escherichia fergusonii ATCC 35469 histidyl-tRNA synthetase YP_002381840.1 662220 D 585054 CDS YP_002381841.1 218548050 7122203 663527..664147 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 664147 yfgM 7122203 yfgM Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381841.1 663527 D 585054 CDS YP_002381842.1 218548051 7121461 664158..665336 1 NC_011740.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis; outer membrane protein assembly complex subunit YfgL 665336 yfgL 7121461 yfgL Escherichia fergusonii ATCC 35469 outer membrane protein assembly complex subunit YfgL YP_002381842.1 664158 D 585054 CDS YP_002381843.1 218548052 7121460 665455..666927 1 NC_011740.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 666927 engA 7121460 engA Escherichia fergusonii ATCC 35469 GTP-binding protein EngA YP_002381843.1 665455 D 585054 CDS YP_002381844.1 218548053 7122891 666990..667205 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 667205 7122891 EFER_0662 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381844.1 666990 D 585054 CDS YP_002381845.1 218548054 7123121 667397..669589 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8500884, 3304658, 12540539; Product type pf : factor; intimin 669589 7123121 EFER_0663 Escherichia fergusonii ATCC 35469 intimin YP_002381845.1 667397 D 585054 CDS YP_002381846.1 218548055 7120211 669639..670637 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 670637 7120211 EFER_0664 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381846.1 669639 D 585054 CDS YP_002381847.1 218548056 7123662 670747..678834 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 678834 7123662 EFER_0665 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381847.1 670747 D 585054 CDS YP_002381848.1 218548057 7120212 complement(678889..680256) 1 NC_011740.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 680256 xseA 7120212 xseA Escherichia fergusonii ATCC 35469 exodeoxyribonuclease VII large subunit YP_002381848.1 678889 R 585054 CDS YP_002381849.1 218548058 7122385 680418..681884 1 NC_011740.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 681884 guaB 7122385 guaB Escherichia fergusonii ATCC 35469 inosine 5'-monophosphate dehydrogenase YP_002381849.1 680418 D 585054 CDS YP_002381850.1 218548059 7123190 681953..683530 1 NC_011740.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 683530 guaA 7123190 guaA Escherichia fergusonii ATCC 35469 GMP synthase YP_002381850.1 681953 D 585054 CDS YP_002381851.1 218548060 7120623 complement(683618..684244) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 684244 7120623 EFER_0669 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381851.1 683618 R 585054 CDS YP_002381852.1 218548061 7120213 complement(684350..684898) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 684898 yfgI 7120213 yfgI Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381852.1 684350 R 585054 CDS YP_002381853.1 218548062 7121459 complement(684914..685477) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; outer membrane lipoprotein 685477 yfgH 7121459 yfgH Escherichia fergusonii ATCC 35469 outer membrane lipoprotein YP_002381853.1 684914 R 585054 CDS YP_002381854.1 218548063 7123324 685619..685912 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 685912 7123324 EFER_0672 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381854.1 685619 D 585054 CDS YP_002381855.1 218548064 7120214 686282..688531 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 688531 7120214 EFER_0673 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381855.1 686282 D 585054 CDS YP_002381856.1 218548065 7120215 complement(688602..690221) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93107072, 94025037, 94165003, 8212131, 8380170; Product type e : enzyme; exopolyphosphatase 690221 ppx 7120215 ppx Escherichia fergusonii ATCC 35469 exopolyphosphatase YP_002381856.1 688602 R 585054 CDS YP_002381857.1 218548066 7120118 complement(690139..692205) 1 NC_011740.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 692205 ppk 7120118 ppk Escherichia fergusonii ATCC 35469 polyphosphate kinase YP_002381857.1 690139 R 585054 CDS YP_002381858.1 218548067 7123646 complement(692406..693047) 1 NC_011740.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 693047 purN 7123646 purN Escherichia fergusonii ATCC 35469 phosphoribosylglycinamide formyltransferase YP_002381858.1 692406 R 585054 CDS YP_002381859.1 218548068 7122326 complement(693044..694081) 1 NC_011740.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 694081 purM 7122326 purM Escherichia fergusonii ATCC 35469 phosphoribosylaminoimidazole synthetase YP_002381859.1 693044 R 585054 CDS YP_002381860.1 218548069 7122325 694315..694941 1 NC_011740.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 694941 upp 7122325 upp Escherichia fergusonii ATCC 35469 uracil phosphoribosyltransferase YP_002381860.1 694315 D 585054 CDS YP_002381861.1 218548070 7122640 695027..696316 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8332529, 7721693; Product type t : transporter; uracil transporter 696316 uraA 7122640 uraA Escherichia fergusonii ATCC 35469 uracil transporter YP_002381861.1 695027 D 585054 CDS YP_002381862.1 218548071 7122641 696388..697113 1 NC_011740.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor 697113 hda 7122641 hda Escherichia fergusonii ATCC 35469 DNA replication initiation factor YP_002381862.1 696388 D 585054 CDS YP_002381863.1 218548072 7120632 complement(697147..697506) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; oxidoreductase 697506 yfgD 7120632 yfgD Escherichia fergusonii ATCC 35469 oxidoreductase YP_002381863.1 697147 R 585054 CDS YP_002381864.1 218548073 7123323 complement(697527..698990) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; peptidase 698990 yfgC 7123323 yfgC Escherichia fergusonii ATCC 35469 peptidase YP_002381864.1 697527 R 585054 CDS YP_002381865.1 218548074 7121458 699204..700265 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; permease 700265 perM 7121458 perM Escherichia fergusonii ATCC 35469 permease YP_002381865.1 699204 D 585054 CDS YP_002381866.1 218548075 7122580 complement(700303..702315) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type r : regulator; hydrogenase-4 transcriptional activator 702315 7122580 EFER_0684 Escherichia fergusonii ATCC 35469 hydrogenase-4 transcriptional activator YP_002381866.1 700303 R 585054 CDS YP_002381867.1 218548076 7123663 complement(702312..702740) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; processing element hydrogenase 4 702740 7123663 EFER_0685 Escherichia fergusonii ATCC 35469 processing element hydrogenase 4 YP_002381867.1 702312 R 585054 CDS YP_002381868.1 218548077 7123664 complement(702733..703539) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9387241; Product type c : carrier; hydrogenase 4, Fe-S subunit 703539 hyfI 7123664 hyfI Escherichia fergusonii ATCC 35469 hydrogenase 4, Fe-S subunit YP_002381868.1 702733 R 585054 CDS YP_002381869.1 218548078 7123739 complement(703497..704045) 1 NC_011740.1 probable electron transfer protein for hydrogenase 4; hydrogenase 4 is believed to be silent in E. coli under conditions tested so far; hydrogenase 4 subunit H 704045 7123739 EFER_0687 Escherichia fergusonii ATCC 35469 hydrogenase 4 subunit H YP_002381869.1 703497 R 585054 CDS YP_002381870.1 218548079 7120216 complement(704055..705770) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9387241; Product type c : carrier; hydrogenase 4 subunit 705770 hyfG 7120216 hyfG Escherichia fergusonii ATCC 35469 hydrogenase 4 subunit YP_002381870.1 704055 R 585054 CDS YP_002381871.1 218548080 7120711 complement(705760..707340) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9387241; Product type m : membrane component; hydrogenase 4 subunit F 707340 hyfF 7120711 hyfF Escherichia fergusonii ATCC 35469 hydrogenase 4 subunit F YP_002381871.1 705760 R 585054 CDS YP_002381872.1 218548081 7120710 complement(707345..707995) 1 NC_011740.1 interacts with formate dehydrogenase to produce an active formate hydrogenlyase complex which cleaves formate to dihydrogen and carbon dioxide; hydrogenase 4 membrane subunit 707995 hyfE 7120710 hyfE Escherichia fergusonii ATCC 35469 hydrogenase 4 membrane subunit YP_002381872.1 707345 R 585054 CDS YP_002381873.1 218548082 7123738 complement(708007..709455) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9387241; Product type m : membrane component; hydrogenase 4 subunit D 709455 hyfD 7123738 hyfD Escherichia fergusonii ATCC 35469 hydrogenase 4 subunit D YP_002381873.1 708007 R 585054 CDS YP_002381874.1 218548083 7123208 complement(709462..710409) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9387241; Product type m : membrane component; hydrogenase 4, membrane subunit 710409 hyfC 7123208 hyfC Escherichia fergusonii ATCC 35469 hydrogenase 4, membrane subunit YP_002381874.1 709462 R 585054 CDS YP_002381875.1 218548084 7120709 complement(710420..712495) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hydrogenase 4 subunit B 712495 7120709 EFER_0693 Escherichia fergusonii ATCC 35469 hydrogenase 4 subunit B YP_002381875.1 710420 R 585054 CDS YP_002381876.1 218548085 7120217 complement(712441..713058) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; hydrogenase 4, 4Fe-4S subunit 713058 7120217 EFER_0694 Escherichia fergusonii ATCC 35469 hydrogenase 4, 4Fe-4S subunit YP_002381876.1 712441 R 585054 CDS YP_002381877.1 218548086 7120218 complement(713304..713774) 1 NC_011740.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase 713774 bcp 7120218 bcp Escherichia fergusonii ATCC 35469 thioredoxin-dependent thiol peroxidase YP_002381877.1 713304 R 585054 CDS YP_002381878.1 218548087 7121647 complement(713774..714346) 1 NC_011740.1 negative transcriptional regulator of the gcvTHP operon; glycine cleavage system transcriptional repressor 714346 gcvR 7121647 gcvR Escherichia fergusonii ATCC 35469 glycine cleavage system transcriptional repressor YP_002381878.1 713774 R 585054 CDS YP_002381879.1 218548088 7120181 714493..715371 1 NC_011740.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 715371 dapA 7120181 dapA Escherichia fergusonii ATCC 35469 dihydrodipicolinate synthase YP_002381879.1 714493 D 585054 CDS YP_002381880.1 218548089 7122866 715388..716422 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91358331, 1885529, 2120198; Product type lp : lipoprotein; lipoprotein 716422 nlpB 7122866 nlpB Escherichia fergusonii ATCC 35469 lipoprotein YP_002381880.1 715388 D 585054 CDS YP_002381881.1 218548090 7120697 716634..717347 1 NC_011740.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazolesuccinocarboxamide synthase 717347 purC 7120697 purC Escherichia fergusonii ATCC 35469 phosphoribosylaminoimidazolesuccinocarboxamide synthase YP_002381881.1 716634 D 585054 CDS YP_002381882.1 218548091 7122319 717515..718378 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 718378 ypfJ 7122319 ypfJ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381882.1 717515 D 585054 CDS YP_002381883.1 218548092 7121748 718393..720408 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hydrolase 720408 ypfI 7121748 ypfI Escherichia fergusonii ATCC 35469 hydrolase YP_002381883.1 718393 D 585054 CDS YP_002381884.1 218548093 7123369 720482..721180 1 NC_011740.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YpfH 721180 ypfH 7123369 ypfH Escherichia fergusonii ATCC 35469 esterase YpfH YP_002381884.1 720482 D 585054 CDS YP_002381885.1 218548094 7121747 complement(721273..721473) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 721473 ypfN 7121747 ypfN Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381885.1 721273 R 585054 CDS YP_002381886.1 218548095 7121749 complement(721501..722628) 1 NC_011740.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 722628 dapE 7121749 dapE Escherichia fergusonii ATCC 35469 succinyl-diaminopimelate desuccinylase YP_002381886.1 721501 R 585054 CDS YP_002381887.1 218548096 7122867 complement(722632..722988) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 722988 yffB 7122867 yffB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381887.1 722632 R 585054 CDS YP_002381888.1 218548097 7121453 complement(723538..726651) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12426336, 20158894, 21450803, 79216220, 10692383, 1644752; Product type t : transporter; aminoglycoside/multidrug efflux system 726651 acrD 7121453 acrD Escherichia fergusonii ATCC 35469 aminoglycoside/multidrug efflux system YP_002381888.1 723538 R 585054 CDS YP_002381889.1 218548098 7122267 complement(726770..728482) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92374842, 1508040, 1528845; Product type r : regulator; nitrate/nitrite sensor protein NarQ 728482 narQ 7122267 narQ Escherichia fergusonii ATCC 35469 nitrate/nitrite sensor protein NarQ YP_002381889.1 726770 R 585054 CDS YP_002381890.1 218548099 7120680 728567..730675 1 NC_011740.1 unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit 730675 aegA 7120680 aegA Escherichia fergusonii ATCC 35469 oxidoreductase Fe-S binding subunit YP_002381890.1 728567 D 585054 CDS YP_002381891.1 218548100 7123456 730743..731318 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; NUDIX hydrolase 731318 yffH 7123456 yffH Escherichia fergusonii ATCC 35469 NUDIX hydrolase YP_002381891.1 730743 D 585054 CDS YP_002381892.1 218548101 7121454 731417..732484 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 732484 ypfG 7121454 ypfG Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381892.1 731417 D 585054 CDS YP_002381893.1 218548102 7121746 complement(732503..734506) 1 NC_011740.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 734506 tktB 7121746 tktB Escherichia fergusonii ATCC 35469 transketolase YP_002381893.1 732503 R 585054 CDS YP_002381894.1 218548103 7122135 complement(734529..735479) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90230300; Product type e : enzyme; transaldolase A 735479 talA 7122135 talA Escherichia fergusonii ATCC 35469 transaldolase A YP_002381894.1 734529 R 585054 CDS YP_002381895.1 218548104 7121972 735754..738033 1 NC_011740.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 738033 maeB 7121972 maeB Escherichia fergusonii ATCC 35469 malic enzyme YP_002381895.1 735754 D 585054 CDS YP_002381896.1 218548105 7121221 738328..738663 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type ps : structure; carboxysome-like ethanolaminosome structural protein 738663 ypfE 7121221 ypfE Escherichia fergusonii ATCC 35469 carboxysome-like ethanolaminosome structural protein YP_002381896.1 738328 D 585054 CDS YP_002381897.1 218548106 7121745 738676..739155 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type pe : enzyme; nucleoside triphosphate hydrolase domain-containing protein 739155 eutP 7121745 eutP Escherichia fergusonii ATCC 35469 nucleoside triphosphate hydrolase domain-containing protein YP_002381897.1 738676 D 585054 CDS YP_002381898.1 218548107 7119972 739130..739831 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10464203; hypothetical protein 739831 eutQ 7119972 eutQ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381898.1 739130 D 585054 CDS YP_002381899.1 218548108 7119973 739828..740631 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type pe : enzyme; cobalamin adenosyltransferase 740631 eutT 7119973 eutT Escherichia fergusonii ATCC 35469 cobalamin adenosyltransferase YP_002381899.1 739828 D 585054 CDS YP_002381900.1 218548109 7123623 740628..741644 1 NC_011740.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 741644 eutD 7123623 eutD Escherichia fergusonii ATCC 35469 phosphotransacetylase YP_002381900.1 740628 D 585054 CDS YP_002381901.1 218548110 7123622 741683..741976 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type ps : structure; carboxysome-like ethanolaminosome structural protein 741976 cchA 7123622 cchA Escherichia fergusonii ATCC 35469 carboxysome-like ethanolaminosome structural protein YP_002381901.1 741683 D 585054 CDS YP_002381902.1 218548111 7120865 742083..742370 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type ps : structure; carboxysome-like ethanolaminosome structural protein 742370 cchB 7120865 cchB Escherichia fergusonii ATCC 35469 carboxysome-like ethanolaminosome structural protein YP_002381902.1 742083 D 585054 CDS YP_002381903.1 218548112 7120866 742382..743785 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type pe : enzyme; aldehyde dehydrogenase 743785 eutE 7120866 eutE Escherichia fergusonii ATCC 35469 aldehyde dehydrogenase YP_002381903.1 742382 D 585054 CDS YP_002381904.1 218548113 7119968 743796..744632 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type pf : factor; chaperonin 744632 eutJ 7119968 eutJ Escherichia fergusonii ATCC 35469 chaperonin YP_002381904.1 743796 D 585054 CDS YP_002381905.1 218548114 7119970 744622..745809 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type pe : enzyme; alcohol dehydrogenase 745809 eutG 7119970 eutG Escherichia fergusonii ATCC 35469 alcohol dehydrogenase YP_002381905.1 744622 D 585054 CDS YP_002381906.1 218548115 7119969 745926..747152 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7868611, 10464203; Product type pt : transporter; ethanolamine transporter 747152 eutH 7119969 eutH Escherichia fergusonii ATCC 35469 ethanolamine transporter YP_002381906.1 745926 D 585054 CDS YP_002381907.1 218548116 7123621 747149..748552 1 NC_011740.1 ethanolamine utilization protein EutA; reactivating factor for ethanolamine ammonia lyase 748552 eutA 7123621 eutA Escherichia fergusonii ATCC 35469 reactivating factor for ethanolamine ammonia lyase YP_002381907.1 747149 D 585054 CDS YP_002381908.1 218548117 7119966 748564..749925 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3905806, 10464203; Product type e : enzyme; ethanolamine ammonia-lyase large subunit 749925 eutB 7119966 eutB Escherichia fergusonii ATCC 35469 ethanolamine ammonia-lyase large subunit YP_002381908.1 748564 D 585054 CDS YP_002381909.1 218548118 7119967 749946..750833 1 NC_011740.1 catalyzes the formation of acetaldehyde from ethanolamine; ethanolamine ammonia-lyase small subunit 750833 eutC 7119967 eutC Escherichia fergusonii ATCC 35469 ethanolamine ammonia-lyase small subunit YP_002381909.1 749946 D 585054 CDS YP_002381910.1 218548119 7123620 750843..751502 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type ps : structure; carboxysome-like ethanolaminosome structural protein 751502 eutL 7123620 eutL Escherichia fergusonii ATCC 35469 carboxysome-like ethanolaminosome structural protein YP_002381910.1 750843 D 585054 CDS YP_002381911.1 218548120 7119971 751515..752015 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10464203; Product type ps : structure; ethanolaminosome structural protein 752015 yffI 7119971 yffI Escherichia fergusonii ATCC 35469 ethanolaminosome structural protein YP_002381911.1 751515 D 585054 CDS YP_002381912.1 218548121 7121455 752061..753113 1 NC_011740.1 activates the transcription of the ethanolamine utilization operon; transcriptional regulator EutR 753113 yfeG 7121455 yfeG Escherichia fergusonii ATCC 35469 transcriptional regulator EutR YP_002381912.1 752061 D 585054 CDS YP_002381913.1 218548122 7121446 complement(753190..753582) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 753582 7121446 EFER_0734 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381913.1 753190 R 585054 CDS YP_002381914.1 218548123 7123122 complement(753546..754808) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 754808 7123122 EFER_0735 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381914.1 753546 R 585054 CDS YP_002381915.1 218548124 7120219 complement(754946..755845) 1 NC_011740.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 755845 hemF 7120219 hemF Escherichia fergusonii ATCC 35469 coproporphyrinogen III oxidase YP_002381915.1 754946 R 585054 CDS YP_002381916.1 218548125 7122182 complement(755849..756718) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21348478, 6137479, 87242501, 1903834, 8300522; Product type e : enzyme; N-acetylmuramoyl-l-alanine amidase I 756718 amiA 7122182 amiA Escherichia fergusonii ATCC 35469 N-acetylmuramoyl-l-alanine amidase I YP_002381916.1 755849 R 585054 CDS YP_002381917.1 218548126 7124015 756931..757356 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; acetyltransferase 757356 ypeA 7124015 ypeA Escherichia fergusonii ATCC 35469 acetyltransferase YP_002381917.1 756931 D 585054 CDS YP_002381918.1 218548127 7121744 757343..757792 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 757792 yfeZ 7121744 yfeZ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381918.1 757343 D 585054 CDS YP_002381919.1 218548128 7121452 757853..758428 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12900013, 7764507; hypothetical protein 758428 yfeY 7121452 yfeY Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381919.1 757853 D 585054 CDS YP_002381920.1 218548129 7121451 758524..759423 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 759423 yfeX 7121451 yfeX Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381920.1 758524 D 585054 CDS YP_002381921.1 218548130 7123870 complement(759520..760785) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15983044, 15060041; Product type e : enzyme; hypothetical protein 760785 murQ 7123870 murQ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381921.1 759520 R 585054 CDS YP_002381922.1 218548131 7120651 complement(760788..762212) 1 NC_011740.1 belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component; PTS system N-acetylmuramic acid transporter subunit IIBC 762212 murP 7120651 murP Escherichia fergusonii ATCC 35469 PTS system N-acetylmuramic acid transporter subunit IIBC YP_002381922.1 760788 R 585054 CDS YP_002381923.1 218548132 7120650 complement(762216..763112) 1 NC_011740.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase 763112 murQ 7120650 murQ Escherichia fergusonii ATCC 35469 N-acetylmuramic acid 6-phosphate etherase YP_002381923.1 762216 R 585054 CDS YP_002381924.1 218548133 7123869 763276..764133 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator 764133 yfeT 7123869 yfeT Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YP_002381924.1 763276 D 585054 CDS YP_002381925.1 218548134 7121450 764262..765053 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 97385354, 2188959, 7984428, 9241368; Product type pe : enzyme; short chain dehydrogenase 765053 ucpA 7121450 ucpA Escherichia fergusonii ATCC 35469 short chain dehydrogenase YP_002381925.1 764262 D 585054 CDS YP_002381926.1 218548135 7124074 765357..766373 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90264335, 2188959, 9298646; Product type t : transporter; thiosulfate transporter subunit 766373 cysP 7124074 cysP Escherichia fergusonii ATCC 35469 thiosulfate transporter subunit YP_002381926.1 765357 D 585054 CDS YP_002381927.1 218548136 7122854 766373..767206 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90264334, 2188958; Product type t : transporter; sulfate/thiosulfate transporter subunit 767206 cysU 7122854 cysU Escherichia fergusonii ATCC 35469 sulfate/thiosulfate transporter subunit YP_002381927.1 766373 D 585054 CDS YP_002381928.1 218548137 7122857 767206..768081 1 NC_011740.1 Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import; sulfate/thiosulfate transporter permease subunit 768081 cysW 7122857 cysW Escherichia fergusonii ATCC 35469 sulfate/thiosulfate transporter permease subunit YP_002381928.1 767206 D 585054 CDS YP_002381929.1 218548138 7122858 768071..769168 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90202710, 90264334, 2188958, 7665461; Product type t : transporter; sulfate/thiosulfate transporter subunit 769168 cysA 7122858 cysA Escherichia fergusonii ATCC 35469 sulfate/thiosulfate transporter subunit YP_002381929.1 768071 D 585054 CDS YP_002381930.1 218548139 7122845 769303..770214 1 NC_011740.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; cysteine synthase B 770214 cysM 7122845 cysM Escherichia fergusonii ATCC 35469 cysteine synthase B YP_002381930.1 769303 D 585054 CDS YP_002381931.1 218548140 7123544 complement(770217..770585) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 770585 yfeK 7123544 yfeK Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381931.1 770217 R 585054 CDS YP_002381932.1 218548141 7121448 770690..771541 1 NC_011740.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxal kinase 771541 pdxK 7121448 pdxK Escherichia fergusonii ATCC 35469 pyridoxal kinase YP_002381932.1 770690 D 585054 CDS YP_002381933.1 218548142 7122573 complement(771585..772094) 1 NC_011740.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter 772094 crr 7122573 crr Escherichia fergusonii ATCC 35469 PTS system glucose-specific transporter YP_002381933.1 771585 R 585054 CDS YP_002381934.1 218548143 7122809 complement(772135..773862) 1 NC_011740.1 Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase 773862 ptsI 7122809 ptsI Escherichia fergusonii ATCC 35469 phosphoenolpyruvate-protein phosphotransferase YP_002381934.1 772135 R 585054 CDS YP_002381935.1 218548144 7123462 complement(773909..774166) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type t : transporter; PTS system phosphohistidinoprotein-hexose phosphotransferase Hpr 774166 ptsH 7123462 ptsH Escherichia fergusonii ATCC 35469 PTS system phosphohistidinoprotein-hexose phosphotransferase Hpr YP_002381935.1 773909 R 585054 CDS YP_002381936.1 218548145 7122315 complement(774548..775519) 1 NC_011740.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A 775519 cysK 7122315 cysK Escherichia fergusonii ATCC 35469 cysteine synthase A YP_002381936.1 774548 R 585054 CDS YP_002381937.1 218548146 7122853 complement(775683..776444) 1 NC_011740.1 role in sulfur assimilation; sulfate transport protein CysZ 776444 cysZ 7122853 cysZ Escherichia fergusonii ATCC 35469 sulfate transport protein CysZ YP_002381937.1 775683 R 585054 CDS YP_002381938.1 218548147 7124114 776624..777679 1 NC_011740.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA 777679 zipA 7124114 zipA Escherichia fergusonii ATCC 35469 cell division protein ZipA YP_002381938.1 776624 D 585054 CDS YP_002381939.1 218548148 7119772 777750..779765 1 NC_011740.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 779765 ligA 7119772 ligA Escherichia fergusonii ATCC 35469 NAD-dependent DNA ligase LigA YP_002381939.1 777750 D 585054 CDS YP_002381940.1 218548149 7120832 779674..779985 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 779985 7120832 EFER_0764 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381940.1 779674 D 585054 CDS YP_002381941.1 218548150 7120220 complement(779982..780980) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; sodium/bile acid symporter familyprotein 780980 yfeH 7120220 yfeH Escherichia fergusonii ATCC 35469 sodium/bile acid symporter familyprotein YP_002381941.1 779982 R 585054 CDS YP_002381942.1 218548151 7121447 complement(781257..782036) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 782036 yfeN 7121447 yfeN Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381942.1 781257 R 585054 CDS YP_002381943.1 218548152 7121449 782292..783125 1 NC_011740.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 783125 xapA 7121449 xapA Escherichia fergusonii ATCC 35469 purine nucleoside phosphorylase YP_002381943.1 782292 D 585054 CDS YP_002381944.1 218548153 7122381 783183..784439 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96032385, 7559336; Product type t : transporter; xanthosine transporter 784439 xapB 7122381 xapB Escherichia fergusonii ATCC 35469 xanthosine transporter YP_002381944.1 783183 D 585054 CDS YP_002381945.1 218548154 7122382 784809..785693 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7559336; Product type r : regulator; DNA-binding transcriptional activator XapR 785693 xapR 7122382 xapR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional activator XapR YP_002381945.1 784809 D 585054 CDS YP_002381946.1 218548155 7120084 786402..787817 1 NC_011740.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 787817 gltX 7120084 gltX Escherichia fergusonii ATCC 35469 glutamyl-tRNA synthetase YP_002381946.1 786402 D 585054 CDS YP_002381947.1 218548156 7120588 complement(787865..788257) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; nucleic acid-binding transcriptional regulator 788257 yfeD 7120588 yfeD Escherichia fergusonii ATCC 35469 nucleic acid-binding transcriptional regulator YP_002381947.1 787865 R 585054 CDS YP_002381948.1 218548157 7123321 complement(788259..788618) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; nucleic acid-binding transcriptional regulator 788618 yfeC 7123321 yfeC Escherichia fergusonii ATCC 35469 nucleic acid-binding transcriptional regulator YP_002381948.1 788259 R 585054 CDS YP_002381949.1 218548158 7123091 789165..791423 1 NC_011740.1 hypothetical protein 791423 7123091 EFER_0775 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381949.1 789165 D 585054 CDS YP_002381950.1 218548159 7120221 complement(791516..792718) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 374403, 8022285, 7007808, 827549, 4563236, 1512211; Product type t : transporter; nucleoside (except guanosine) transporter 792718 nupC 7120221 nupC Escherichia fergusonii ATCC 35469 nucleoside (except guanosine) transporter YP_002381950.1 791516 R 585054 CDS YP_002381951.1 218548160 7123576 793054..794292 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20177822, 20305051, 10712688, 10844693; Product type t : transporter; manganese transport protein MntH 794292 mntH 7123576 mntH Escherichia fergusonii ATCC 35469 manganese transport protein MntH YP_002381951.1 793054 D 585054 CDS YP_002381952.1 218548161 7120944 complement(794360..794686) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 794686 ypeC 7120944 ypeC Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381952.1 794360 R 585054 CDS YP_002381953.1 218548162 7123918 complement(794801..796057) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; hypothetical protein 796057 yfeO 7123918 yfeO Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381953.1 794801 R 585054 CDS YP_002381954.1 218548163 7123322 796261..797226 1 NC_011740.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase 797226 glk 7123322 glk Escherichia fergusonii ATCC 35469 glucokinase YP_002381954.1 796261 D 585054 CDS YP_002381955.1 218548164 7120190 797445..797771 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; PTS system transporter subunit IIB 797771 ypdH 7120190 ypdH Escherichia fergusonii ATCC 35469 PTS system transporter subunit IIB YP_002381955.1 797445 D 585054 CDS YP_002381956.1 218548165 7121743 797793..799040 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; PTS system transporter subunit IIC 799040 ypdG 7121743 ypdG Escherichia fergusonii ATCC 35469 PTS system transporter subunit IIC YP_002381956.1 797793 D 585054 CDS YP_002381957.1 218548166 7123917 799055..800140 1 NC_011740.1 Xaa-Pro aminopeptidase; limited methionine aminopeptidase; aminopeptidase 800140 ypdF 7123917 ypdF Escherichia fergusonii ATCC 35469 aminopeptidase YP_002381957.1 799055 D 585054 CDS YP_002381958.1 218548167 7121742 800140..801177 1 NC_011740.1 metalloprotein; exoaminopeptidase 801177 ypdE 7121742 ypdE Escherichia fergusonii ATCC 35469 exoaminopeptidase YP_002381958.1 800140 D 585054 CDS YP_002381959.1 218548168 7121741 801202..803697 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; PTS system transporter protein Hpr /enzyme I /subunit IIA 803697 ypdD 7121741 ypdD Escherichia fergusonii ATCC 35469 PTS system transporter protein Hpr /enzyme I /subunit IIA YP_002381959.1 801202 D 585054 CDS YP_002381960.1 218548169 7121740 complement(803700..804557) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding protein 804557 ypdC 7121740 ypdC Escherichia fergusonii ATCC 35469 DNA-binding protein YP_002381960.1 803700 R 585054 CDS YP_002381961.1 218548170 7123916 complement(804569..805303) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15522865; Product type pr : regulator; response regulator in two-component system with YpdA 805303 ypdB 7123916 ypdB Escherichia fergusonii ATCC 35469 response regulator in two-component system with YpdA YP_002381961.1 804569 R 585054 CDS YP_002381962.1 218548171 7121739 complement(805318..807015) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15522865; Product type prc : receptor; sensory kinase in two-component system with YpdB 807015 ypdA 7121739 ypdA Escherichia fergusonii ATCC 35469 sensory kinase in two-component system with YpdB YP_002381962.1 805318 R 585054 CDS YP_002381963.1 218548172 7121738 807392..808630 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; aminotransferase 808630 yfdZ 7121738 yfdZ Escherichia fergusonii ATCC 35469 aminotransferase YP_002381963.1 807392 D 585054 CDS YP_002381964.1 218548173 7121444 complement(809118..810044) 1 NC_011740.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock; lipid A biosynthesis palmitoleoyl acyltransferase 810044 ddg 7121444 ddg Escherichia fergusonii ATCC 35469 lipid A biosynthesis palmitoleoyl acyltransferase YP_002381964.1 809118 R 585054 CDS YP_002381965.1 218548174 7122151 810411..810659 1 NC_011740.1 hypothetical protein 810659 7122151 EFER_0791 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381965.1 810411 D 585054 CDS YP_002381966.1 218548175 7120222 complement(810785..812170) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; tartrate transporter 812170 7120222 EFER_0792 Escherichia fergusonii ATCC 35469 tartrate transporter YP_002381966.1 810785 R 585054 CDS YP_002381967.1 218548176 7123123 812457..812930 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional repressor of for multidrug resistance pump (MarR family) 812930 7123123 EFER_0793 Escherichia fergusonii ATCC 35469 transcriptional repressor of for multidrug resistance pump (MarR family) YP_002381967.1 812457 D 585054 CDS YP_002381968.1 218548177 7120223 813253..814383 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; amidase 814383 7120223 EFER_0794 Escherichia fergusonii ATCC 35469 amidase YP_002381968.1 813253 D 585054 CDS YP_002381969.1 218548178 7120224 814456..815616 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 815616 7120224 EFER_0795 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381969.1 814456 D 585054 CDS YP_002381970.1 218548179 7120225 815637..815987 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 815987 7120225 EFER_0796 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381970.1 815637 D 585054 CDS YP_002381971.1 218548180 7120226 815998..816510 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 816510 7120226 EFER_0797 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381971.1 815998 D 585054 CDS YP_002381972.1 218548181 7120227 816522..817823 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; ring hydroxylating dioxygenase subunit alpha 817823 7120227 EFER_0798 Escherichia fergusonii ATCC 35469 ring hydroxylating dioxygenase subunit alpha YP_002381972.1 816522 D 585054 CDS YP_002381973.1 218548182 7120228 817793..818302 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; aromatic-ring-hydroxylating dioxygenase subunit beta 818302 7120228 EFER_0799 Escherichia fergusonii ATCC 35469 aromatic-ring-hydroxylating dioxygenase subunit beta YP_002381973.1 817793 D 585054 CDS YP_002381974.1 218548183 7120229 818271..819053 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; 3-oxoacyl-ACP reductase 819053 7120229 EFER_0800 Escherichia fergusonii ATCC 35469 3-oxoacyl-ACP reductase YP_002381974.1 818271 D 585054 CDS YP_002381975.1 218548184 7120230 819063..819995 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; vanillate O-demethylase oxidoreductase 819995 7120230 EFER_0801 Escherichia fergusonii ATCC 35469 vanillate O-demethylase oxidoreductase YP_002381975.1 819063 D 585054 CDS YP_002381976.1 218548185 7123124 820006..820506 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; flavin:NADH reductase ycdH 820506 7123124 EFER_0802 Escherichia fergusonii ATCC 35469 flavin:NADH reductase ycdH YP_002381976.1 820006 D 585054 CDS YP_002381977.1 218548186 7120231 820527..821855 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type t : transporter; General substrate transporter:Major facilitator superfamily 821855 7120231 EFER_0803 Escherichia fergusonii ATCC 35469 General substrate transporter:Major facilitator superfamily YP_002381977.1 820527 D 585054 CDS YP_002381978.1 218548187 7120232 822540..824006 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 824006 7120232 EFER_0804 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381978.1 822540 D 585054 CDS YP_002381979.1 218548188 7120233 complement(824270..824551) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; Ogr family transcription activator 824551 7120233 EFER_0805 Escherichia fergusonii ATCC 35469 Ogr family transcription activator YP_002381979.1 824270 R 585054 CDS YP_002381980.1 218548189 7120234 complement(824548..825099) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3295254; Product type h : extrachromosomal origin; polarity suppression protein from phage origin 825099 7120234 EFER_0806 Escherichia fergusonii ATCC 35469 polarity suppression protein from phage origin YP_002381980.1 824548 R 585054 CDS YP_002381981.1 218548190 7123665 complement(825096..825839) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3295254; Product type ps : structure; capsid morphogenesis protein from phage 825839 7123665 EFER_0807 Escherichia fergusonii ATCC 35469 capsid morphogenesis protein from phage YP_002381981.1 825096 R 585054 CDS YP_002381982.1 218548191 7123666 complement(826240..828912) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; inner membrane protein from phage origin 828912 7123666 EFER_0808 Escherichia fergusonii ATCC 35469 inner membrane protein from phage origin YP_002381982.1 826240 R 585054 CDS YP_002381983.1 218548192 7120235 complement(828909..829292) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 829292 7120235 EFER_0809 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381983.1 828909 R 585054 CDS YP_002381984.1 218548193 7120236 complement(829289..829573) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 829573 7120236 EFER_0810 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381984.1 829289 R 585054 CDS YP_002381985.1 218548194 7120237 complement(829605..829994) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 829994 7120237 EFER_0811 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381985.1 829605 R 585054 CDS YP_002381986.1 218548195 7123125 complement(829957..830187) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Phage immunity repressor protein (fragment) 830187 7123125 EFER_0812 Escherichia fergusonii ATCC 35469 Phage immunity repressor protein (fragment) YP_002381986.1 829957 R 585054 CDS YP_002381987.1 218548196 7120238 830250..830444 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 830444 7120238 EFER_0813 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381987.1 830250 D 585054 CDS YP_002381988.1 218548197 7120239 complement(830494..830709) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 830709 7120239 EFER_0814 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381988.1 830494 R 585054 CDS YP_002381989.1 218548198 7120240 complement(830812..831693) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 831693 7120240 EFER_0815 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381989.1 830812 R 585054 CDS YP_002381990.1 218548199 7120241 complement(831724..833058) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; phage integrase 833058 int 7120241 int Escherichia fergusonii ATCC 35469 phage integrase YP_002381990.1 831724 R 585054 CDS YP_002381991.1 218548200 7120083 complement(833333..834274) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 834274 yfdC 7120083 yfdC Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381991.1 833333 R 585054 CDS YP_002381992.1 218548201 7123057 834563..835318 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8145644, 15352239; Product type lp : lipoprotein; lipoprotein 835318 vacJ 7123057 vacJ Escherichia fergusonii ATCC 35469 lipoprotein YP_002381992.1 834563 D 585054 CDS YP_002381993.1 218548202 7122655 complement(835398..836771) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15178802, 2840553, 3286621, 91100327, 1987139, 9119048; Product type t : transporter; long-chain fatty acid outer membrane transporter 836771 fadL 7122655 fadL Escherichia fergusonii ATCC 35469 long-chain fatty acid outer membrane transporter YP_002381993.1 835398 R 585054 CDS YP_002381994.1 218548203 7123084 837087..837395 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 837395 yfcZ 7123084 yfcZ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002381994.1 837087 D 585054 CDS YP_002381995.1 218548204 7123056 837734..839044 1 NC_011740.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth; 3-ketoacyl-CoA thiolase 839044 fadI 7123056 fadI Escherichia fergusonii ATCC 35469 3-ketoacyl-CoA thiolase YP_002381995.1 837734 D 585054 CDS YP_002381996.1 218548205 7119829 839044..841188 1 NC_011740.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; multifunctional fatty acid oxidation complex subunit alpha 841188 fadJ 7119829 fadJ Escherichia fergusonii ATCC 35469 multifunctional fatty acid oxidation complex subunit alpha YP_002381996.1 839044 D 585054 CDS YP_002381997.1 218548206 7119828 841394..841879 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10089421, 20200300, 9489669; Product type e : enzyme; phosphohistidine phosphatase 841879 sixA 7119828 sixA Escherichia fergusonii ATCC 35469 phosphohistidine phosphatase YP_002381997.1 841394 D 585054 CDS YP_002381998.1 218548207 7121788 842448..843008 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; fimbrial-like adhesin protein 843008 yfcV 7121788 yfcV Escherichia fergusonii ATCC 35469 fimbrial-like adhesin protein YP_002381998.1 842448 D 585054 CDS YP_002381999.1 218548208 7119827 843083..845731 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; outer membrane usher protein yfcU 845731 7119827 EFER_0826 Escherichia fergusonii ATCC 35469 outer membrane usher protein yfcU YP_002381999.1 843083 D 585054 CDS YP_002382000.1 218548209 7123126 845751..846503 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; periplasmic pilus chaperone 846503 yfcS 7123126 yfcS Escherichia fergusonii ATCC 35469 periplasmic pilus chaperone YP_002382000.1 845751 D 585054 CDS YP_002382001.1 218548210 7119826 846519..847034 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; fimbrial-like adhesin protein 847034 yfcR 7119826 yfcR Escherichia fergusonii ATCC 35469 fimbrial-like adhesin protein YP_002382001.1 846519 D 585054 CDS YP_002382002.1 218548211 7119825 847031..847519 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; fimbrial-like adhesin protein 847519 yfcQ 7119825 yfcQ Escherichia fergusonii ATCC 35469 fimbrial-like adhesin protein YP_002382002.1 847031 D 585054 CDS YP_002382003.1 218548212 7119824 847516..848055 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; fimbrial-like adhesin protein 848055 yfcP 7119824 yfcP Escherichia fergusonii ATCC 35469 fimbrial-like adhesin protein YP_002382003.1 847516 D 585054 CDS YP_002382004.1 218548213 7119823 848042..848881 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 848881 yfcO 7119823 yfcO Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382004.1 848042 D 585054 CDS YP_002382005.1 218548214 7123599 complement(848936..849487) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 849487 yfcN 7123599 yfcN Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382005.1 848936 R 585054 CDS YP_002382006.1 218548215 7119822 849652..850584 1 NC_011740.1 involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 850584 prmB 7119822 prmB Escherichia fergusonii ATCC 35469 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_002382006.1 849652 D 585054 CDS YP_002382007.1 218548216 7123648 850619..851704 1 NC_011740.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 851704 aroC 7123648 aroC Escherichia fergusonii ATCC 35469 chorismate synthase YP_002382007.1 850619 D 585054 CDS YP_002382008.1 218548217 7123717 851707..852531 1 NC_011740.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase 852531 mepA 7123717 mepA Escherichia fergusonii ATCC 35469 penicillin-insensitive murein endopeptidase YP_002382008.1 851707 D 585054 CDS YP_002382009.1 218548218 7120914 852531..853340 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 853340 yfcA 7120914 yfcA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382009.1 852531 D 585054 CDS YP_002382010.1 218548219 7119816 853340..853888 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 853888 yfcM 7119816 yfcM Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382010.1 853340 D 585054 CDS YP_002382011.1 218548220 7119821 853922..854200 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 854200 yfcL 7119821 yfcL Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382011.1 853922 D 585054 CDS YP_002382012.1 218548221 7123598 complement(854256..856262) 1 NC_011740.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase 856262 mnmC 7123598 mnmC Escherichia fergusonii ATCC 35469 5-methylaminomethyl-2-thiouridine methyltransferase YP_002382012.1 854256 R 585054 CDS YP_002382013.1 218548222 7122160 856421..857641 1 NC_011740.1 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 857641 fabB 7122160 fabB Escherichia fergusonii ATCC 35469 3-oxoacyl-ACP synthase YP_002382013.1 856421 D 585054 CDS YP_002382014.1 218548223 7119979 857874..859052 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; hypothetical protein 859052 yfcJ 7119979 yfcJ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382014.1 857874 D 585054 CDS YP_002382015.1 218548224 7123597 complement(859049..860056) 1 NC_011740.1 in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein; flagella biosynthesis regulator 860056 flk 7123597 flk Escherichia fergusonii ATCC 35469 flagella biosynthesis regulator YP_002382015.1 859049 R 585054 CDS YP_002382016.1 218548225 7122997 860153..861289 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90036695, 91035267, 2681152, 2991861, 3029016; Product type e : enzyme; erythronate-4-phosphate dehydrogenase 861289 pdxB 7122997 pdxB Escherichia fergusonii ATCC 35469 erythronate-4-phosphate dehydrogenase YP_002382016.1 860153 D 585054 CDS YP_002382017.1 218548226 7122572 861355..862368 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 92380957, 92380982, 93123150, 2681152, 2991861, 3029016; Product type pe : enzyme; semialdehyde dehydrogenase 862368 usg 7122572 usg Escherichia fergusonii ATCC 35469 semialdehyde dehydrogenase YP_002382017.1 861355 D 585054 CDS YP_002382018.1 218548227 7122642 862368..863180 1 NC_011740.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 863180 truA 7122642 truA Escherichia fergusonii ATCC 35469 tRNA pseudouridine synthase A YP_002382018.1 862368 D 585054 CDS YP_002382019.1 218548228 7122169 863263..863922 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3029016, 3040734, 7678242; Product type pm : membrane component; hypothetical protein 863922 dedA 7122169 dedA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382019.1 863263 D 585054 CDS YP_002382020.1 218548229 7122882 864078..864992 1 NC_011740.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 864992 accD 7122882 accD Escherichia fergusonii ATCC 35469 acetyl-CoA carboxylase subunit beta YP_002382020.1 864078 D 585054 CDS YP_002382021.1 218548230 7122256 865062..866330 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3040739, 91112811, 92041808, 1989505, 3040734; Product type e : enzyme; bifunctional folylpolyglutamate synthase/dihydrofolate synthase 866330 folC 7122256 folC Escherichia fergusonii ATCC 35469 bifunctional folylpolyglutamate synthase/dihydrofolate synthase YP_002382021.1 865062 D 585054 CDS YP_002382022.1 218548231 7123570 866302..866970 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3040734; hypothetical protein 866970 dedD 7123570 dedD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382022.1 866302 D 585054 CDS YP_002382023.1 218548232 7122883 867229..867717 1 NC_011740.1 membrane protein required for colicin V production; colicin V production protein 867717 cvpA 7122883 cvpA Escherichia fergusonii ATCC 35469 colicin V production protein YP_002382023.1 867229 D 585054 CDS YP_002382024.1 218548233 7122834 867754..869271 1 NC_011740.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 869271 purF 7122834 purF Escherichia fergusonii ATCC 35469 amidophosphoribosyltransferase YP_002382024.1 867754 D 585054 CDS YP_002382025.1 218548234 7122322 869366..869935 1 NC_011740.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 869935 ubiX 7122322 ubiX Escherichia fergusonii ATCC 35469 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_002382025.1 869366 D 585054 CDS YP_002382026.1 218548235 7122621 870200..870982 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 4583243, 87308226, 3040734, 9298646; Product type t : transporter; lysine/arginine/ornithine ABC transporter periplasmic-binding protein 870982 argT 7122621 argT Escherichia fergusonii ATCC 35469 lysine/arginine/ornithine ABC transporter periplasmic-binding protein YP_002382026.1 870200 D 585054 CDS YP_002382027.1 218548236 7120544 871205..871987 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10373434, 6449635, 8161536, 9298646, 9600841, 9740056; Product type t : transporter; histidine/lysine/arginine/ornithine ABC transporter periplasmic-binding protein 871987 hisJ 7120544 hisJ Escherichia fergusonii ATCC 35469 histidine/lysine/arginine/ornithine ABC transporter periplasmic-binding protein YP_002382027.1 871205 D 585054 CDS YP_002382028.1 218548237 7122200 872077..872763 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10373434; Product type t : transporter; histidine/lysine/arginine/ornithine ABC transporter membrane protein 872763 hisQ 7122200 hisQ Escherichia fergusonii ATCC 35469 histidine/lysine/arginine/ornithine ABC transporter membrane protein YP_002382028.1 872077 D 585054 CDS YP_002382029.1 218548238 7123443 872760..873476 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10373434, 3313284; Product type t : transporter; histidine/lysine/arginine/ornithine ABC transporter membrane protein 873476 hisM 7123443 hisM Escherichia fergusonii ATCC 35469 histidine/lysine/arginine/ornithine ABC transporter membrane protein YP_002382029.1 872760 D 585054 CDS YP_002382030.1 218548239 7122201 873484..874257 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10373434, 3313284, 91060556; Product type t : transporter; histidine/lysine/arginine/ornithine transporter subunit 874257 hisP 7122201 hisP Escherichia fergusonii ATCC 35469 histidine/lysine/arginine/ornithine transporter subunit YP_002382030.1 873484 D 585054 CDS YP_002382031.1 218548240 7122202 874454..875356 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transposase 875356 yfcI 7122202 yfcI Escherichia fergusonii ATCC 35469 transposase YP_002382031.1 874454 D 585054 CDS YP_002382032.1 218548241 7119820 complement(875404..876297) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pe : enzyme; hypothetical protein 876297 yfcH 7119820 yfcH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382032.1 875404 R 585054 CDS YP_002382033.1 218548242 7119819 complement(876318..876680) 1 NC_011740.1 catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate; D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase 876680 folX 7119819 folX Escherichia fergusonii ATCC 35469 D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase YP_002382033.1 876318 R 585054 CDS YP_002382034.1 218548243 7123007 complement(876737..877384) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; glutathione S-transferase 877384 yfcG 7123007 yfcG Escherichia fergusonii ATCC 35469 glutathione S-transferase YP_002382034.1 876737 R 585054 CDS YP_002382035.1 218548244 7119818 877446..878165 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 878165 yfcF 7119818 yfcF Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382035.1 877446 D 585054 CDS YP_002382036.1 218548245 7119817 878218..878772 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; phosphodiesterase 878772 yfcE 7119817 yfcE Escherichia fergusonii ATCC 35469 phosphodiesterase YP_002382036.1 878218 D 585054 CDS YP_002382037.1 218548246 7123596 878732..879385 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16430214; Product type pe : enzyme; NUDIX hydrolase 879385 yfcD 7123596 yfcD Escherichia fergusonii ATCC 35469 NUDIX hydrolase YP_002382037.1 878732 D 585054 CDS YP_002382038.1 218548247 7123055 complement(879387..880406) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15223311, 99061204; Product type pr : regulator; transcriptional regulator with PLP domain 880406 7123055 EFER_0865 Escherichia fergusonii ATCC 35469 transcriptional regulator with PLP domain YP_002382038.1 879387 R 585054 CDS YP_002382039.1 218548248 7120242 880656..881099 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; phosphotransferase enzyme IIA component 881099 7120242 EFER_0866 Escherichia fergusonii ATCC 35469 phosphotransferase enzyme IIA component YP_002382039.1 880656 D 585054 CDS YP_002382040.1 218548249 7123667 881167..881451 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; phosphotransferase transport system, IIB component 881451 7123667 EFER_0867 Escherichia fergusonii ATCC 35469 phosphotransferase transport system, IIB component YP_002382040.1 881167 D 585054 CDS YP_002382041.1 218548250 7123668 881468..882862 1 NC_011740.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 882862 ulaA 7123668 ulaA Escherichia fergusonii ATCC 35469 PTS system ascorbate-specific transporter subunit IIC YP_002382041.1 881468 D 585054 CDS YP_002382042.1 218548251 7120243 882859..883689 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; carbohydrate degradation enzyme 883689 7120243 EFER_0869 Escherichia fergusonii ATCC 35469 carbohydrate degradation enzyme YP_002382042.1 882859 D 585054 CDS YP_002382043.1 218548252 7120244 883682..884635 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; carbohydrate degradation enzyme 884635 7120244 EFER_0870 Escherichia fergusonii ATCC 35469 carbohydrate degradation enzyme YP_002382043.1 883682 D 585054 CDS YP_002382044.1 218548253 7120245 complement(884715..886859) 1 NC_011740.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 886859 pta 7120245 pta Escherichia fergusonii ATCC 35469 phosphate acetyltransferase YP_002382044.1 884715 R 585054 CDS YP_002382045.1 218548254 7122311 complement(886936..888138) 1 NC_011740.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 888138 ackA 7122311 ackA Escherichia fergusonii ATCC 35469 acetate kinase YP_002382045.1 886936 R 585054 CDS YP_002382046.1 218548255 7123452 complement(888310..888486) 1 NC_011740.1 hypothetical protein 888486 7123452 EFER_0873 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382046.1 888310 R 585054 CDS YP_002382047.1 218548256 7120246 888477..888932 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 888932 yfbV 7120246 yfbV Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382047.1 888477 D 585054 CDS YP_002382048.1 218548257 7119814 888996..889511 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 889511 yfbU 7119814 yfbU Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382048.1 888996 D 585054 CDS YP_002382049.1 218548258 7119813 889522..890172 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; phosphatase 890172 yfbT 7119813 yfbT Escherichia fergusonii ATCC 35469 phosphatase YP_002382049.1 889522 D 585054 CDS YP_002382050.1 218548259 7123054 890259..892091 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter 892091 yfbS 7123054 yfbS Escherichia fergusonii ATCC 35469 transporter YP_002382050.1 890259 D 585054 CDS YP_002382051.1 218548260 7123053 complement(892131..892850) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15489502; Product type e : enzyme; deoxyribonucleoside 5'-monophosphatase 892850 yfbR 7123053 yfbR Escherichia fergusonii ATCC 35469 deoxyribonucleoside 5'-monophosphatase YP_002382051.1 892131 R 585054 CDS YP_002382052.1 218548261 7119812 complement(892816..894033) 1 NC_011740.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT 894033 yfbQ 7119812 yfbQ Escherichia fergusonii ATCC 35469 aminotransferase AlaT YP_002382052.1 892816 R 585054 CDS YP_002382053.1 218548262 7119811 894966..895904 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12123461, 9882671, 7565112; Product type r : regulator; flagellar, motility and chemotaxis genes DNA-binding transcriptional repressor 895904 lrhA 7119811 lrhA Escherichia fergusonii ATCC 35469 flagellar, motility and chemotaxis genes DNA-binding transcriptional repressor YP_002382053.1 894966 D 585054 CDS YP_002382054.1 218548263 7121205 896521..896964 1 NC_011740.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A 896964 nuoA 7121205 nuoA Escherichia fergusonii ATCC 35469 NADH dehydrogenase subunit A YP_002382054.1 896521 D 585054 CDS YP_002382055.1 218548264 7119674 896980..897642 1 NC_011740.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 897642 nuoB 7119674 nuoB Escherichia fergusonii ATCC 35469 NADH dehydrogenase subunit B YP_002382055.1 896980 D 585054 CDS YP_002382056.1 218548265 7119675 897736..899538 1 NC_011740.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms; NADH:ubiquinone oxidoreductase subunit C/D 899538 nuoC 7119675 nuoC Escherichia fergusonii ATCC 35469 NADH:ubiquinone oxidoreductase subunit C/D YP_002382056.1 897736 D 585054 CDS YP_002382057.1 218548266 7123574 899541..900041 1 NC_011740.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 900041 nuoE 7123574 nuoE Escherichia fergusonii ATCC 35469 NADH dehydrogenase subunit E YP_002382057.1 899541 D 585054 CDS YP_002382058.1 218548267 7123575 900038..901375 1 NC_011740.1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F 901375 nuoF 7123575 nuoF Escherichia fergusonii ATCC 35469 NADH dehydrogenase I subunit F YP_002382058.1 900038 D 585054 CDS YP_002382059.1 218548268 7119676 901422..904154 1 NC_011740.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 904154 nuoG 7119676 nuoG Escherichia fergusonii ATCC 35469 NADH dehydrogenase subunit G YP_002382059.1 901422 D 585054 CDS YP_002382060.1 218548269 7119677 904151..905128 1 NC_011740.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 905128 nuoH 7119677 nuoH Escherichia fergusonii ATCC 35469 NADH dehydrogenase subunit H YP_002382060.1 904151 D 585054 CDS YP_002382061.1 218548270 7119678 905143..905685 1 NC_011740.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 905685 nuoI 7119678 nuoI Escherichia fergusonii ATCC 35469 NADH dehydrogenase subunit I YP_002382061.1 905143 D 585054 CDS YP_002382062.1 218548271 7119679 905697..906251 1 NC_011740.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 906251 nuoJ 7119679 nuoJ Escherichia fergusonii ATCC 35469 NADH dehydrogenase subunit J YP_002382062.1 905697 D 585054 CDS YP_002382063.1 218548272 7123030 906248..906550 1 NC_011740.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 906550 nuoK 7123030 nuoK Escherichia fergusonii ATCC 35469 NADH dehydrogenase subunit K YP_002382063.1 906248 D 585054 CDS YP_002382064.1 218548273 7119680 906547..908388 1 NC_011740.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 908388 nuoL 7119680 nuoL Escherichia fergusonii ATCC 35469 NADH dehydrogenase subunit L YP_002382064.1 906547 D 585054 CDS YP_002382065.1 218548274 7119681 908552..910081 1 NC_011740.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 910081 nuoM 7119681 nuoM Escherichia fergusonii ATCC 35469 NADH dehydrogenase subunit M YP_002382065.1 908552 D 585054 CDS YP_002382066.1 218548275 7123031 910268..911545 1 NC_011740.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 911545 nuoN 7123031 nuoN Escherichia fergusonii ATCC 35469 NADH dehydrogenase subunit N YP_002382066.1 910268 D 585054 CDS YP_002382067.1 218548276 7119682 911688..912404 1 NC_011740.1 hypothetical protein 912404 7119682 EFER_0895 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382067.1 911688 D 585054 CDS YP_002382068.1 218548277 7120247 complement(912399..912974) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 912974 7120247 EFER_0896 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382068.1 912399 R 585054 CDS YP_002382069.1 218548278 7120248 complement(913126..913629) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 913629 yfbM 7120248 yfbM Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382069.1 913126 R 585054 CDS YP_002382070.1 218548279 7119810 913983..915614 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 915614 7119810 EFER_0898 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382070.1 913983 D 585054 CDS YP_002382071.1 218548280 7123127 complement(915671..916705) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; chemotaxis protein (cheV-like) 916705 7123127 EFER_0899 Escherichia fergusonii ATCC 35469 chemotaxis protein (cheV-like) YP_002382071.1 915671 R 585054 CDS YP_002382072.1 218548281 7123128 complement(916717..917679) 1 NC_011740.1 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 917679 elaC 7123128 elaC Escherichia fergusonii ATCC 35469 ribonuclease Z YP_002382072.1 916717 R 585054 CDS YP_002382073.1 218548282 7122944 917700..918161 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 918161 elaA 7122944 elaA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382073.1 917700 D 585054 CDS YP_002382074.1 218548283 7122942 918216..918521 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 918521 elaB 7122942 elaB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382074.1 918216 D 585054 CDS YP_002382075.1 218548284 7122943 918615..919910 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9150206, 96140724, 2666397, 7984428, 8549818, 8764478; Product type e : enzyme; isochorismate synthase 2 919910 menF 7122943 menF Escherichia fergusonii ATCC 35469 isochorismate synthase 2 YP_002382075.1 918615 D 585054 CDS YP_002382076.1 218548285 7123775 919999..921669 1 NC_011740.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 921669 menD 7123775 menD Escherichia fergusonii ATCC 35469 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase YP_002382076.1 919999 D 585054 CDS YP_002382077.1 218548286 7121259 921666..922424 1 NC_011740.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase YfbB 922424 yfbB 7121259 yfbB Escherichia fergusonii ATCC 35469 acyl-CoA thioester hydrolase YfbB YP_002382077.1 921666 D 585054 CDS YP_002382078.1 218548287 7119807 922439..923296 1 NC_011740.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 923296 menB 7119807 menB Escherichia fergusonii ATCC 35469 naphthoate synthase YP_002382078.1 922439 D 585054 CDS YP_002382079.1 218548288 7121257 923296..924258 1 NC_011740.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 924258 menC 7121257 menC Escherichia fergusonii ATCC 35469 O-succinylbenzoate synthase YP_002382079.1 923296 D 585054 CDS YP_002382080.1 218548289 7121258 924255..925610 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96186953, 8626063; Product type e : enzyme; O-succinylbenzoic acid--CoA ligase 925610 menE 7121258 menE Escherichia fergusonii ATCC 35469 O-succinylbenzoic acid--CoA ligase YP_002382080.1 924255 D 585054 CDS YP_002382081.1 218548290 7121260 925723..925989 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96015440, 15569938; Product type pt : transporter; polymyxin resistance protein B 925989 pmrD 7121260 pmrD Escherichia fergusonii ATCC 35469 polymyxin resistance protein B YP_002382081.1 925723 D 585054 CDS YP_002382082.1 218548291 7120091 complement(925983..926651) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 926651 7120091 EFER_0910 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382082.1 925983 R 585054 CDS YP_002382083.1 218548292 7120249 complement(926369..926704) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 926704 yfbW 7120249 yfbW Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382083.1 926369 R 585054 CDS YP_002382084.1 218548293 7119815 complement(926701..928383) 1 NC_011740.1 catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A; 4-amino-4-deoxy-L-arabinose transferase 928383 arnT 7119815 arnT Escherichia fergusonii ATCC 35469 4-amino-4-deoxy-L-arabinose transferase YP_002382084.1 926701 R 585054 CDS YP_002382085.1 218548294 7123715 complement(928353..929255) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 929255 yfbH 7123715 yfbH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382085.1 928353 R 585054 CDS YP_002382086.1 218548295 7119809 complement(929252..931234) 1 NC_011740.1 Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains; bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase 931234 yfbG 7119809 yfbG Escherichia fergusonii ATCC 35469 bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase YP_002382086.1 929252 R 585054 CDS YP_002382087.1 218548296 7123595 complement(931234..932214) 1 NC_011740.1 catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate; undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase 932214 yfbF 7123595 yfbF Escherichia fergusonii ATCC 35469 undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase YP_002382087.1 931234 R 585054 CDS YP_002382088.1 218548297 7123052 complement(932218..933357) 1 NC_011740.1 catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose; UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase 933357 yfbE 7123052 yfbE Escherichia fergusonii ATCC 35469 UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase YP_002382088.1 932218 R 585054 CDS YP_002382089.1 218548298 7119808 933688..934269 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 934269 ais 7119808 ais Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382089.1 933688 D 585054 CDS YP_002382090.1 218548299 7122290 complement(934309..934734) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16430214; Product type pe : enzyme; NUDIX hydrolase 934734 yfaO 7122290 yfaO Escherichia fergusonii ATCC 35469 NUDIX hydrolase YP_002382090.1 934309 R 585054 CDS YP_002382091.1 218548300 7123051 934964..935506 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; outer membrane porin protein 935506 yfaZ 7123051 yfaZ Escherichia fergusonii ATCC 35469 outer membrane porin protein YP_002382091.1 934964 D 585054 CDS YP_002382092.1 218548301 7119806 935606..936808 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; competence damage-inducible protein A 936808 yfaY 7119806 yfaY Escherichia fergusonii ATCC 35469 competence damage-inducible protein A YP_002382092.1 935606 D 585054 CDS YP_002382093.1 218548302 7119805 937027..937374 1 NC_011740.1 hypothetical protein 937374 7119805 EFER_0921 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382093.1 937027 D 585054 CDS YP_002382094.1 218548303 7120250 complement(937416..938342) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 938342 yfaD 7120250 yfaD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382094.1 937416 R 585054 CDS YP_002382095.1 218548304 7119802 complement(938536..939726) 1 NC_011740.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C 939726 glpC 7119802 glpC Escherichia fergusonii ATCC 35469 sn-glycerol-3-phosphate dehydrogenase subunit C YP_002382095.1 938536 R 585054 CDS YP_002382096.1 218548305 7120205 complement(939723..940982) 1 NC_011740.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B 940982 glpB 7120205 glpB Escherichia fergusonii ATCC 35469 anaerobic glycerol-3-phosphate dehydrogenase subunit B YP_002382096.1 939723 R 585054 CDS YP_002382097.1 218548306 7120204 complement(940972..942600) 1 NC_011740.1 anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A 942600 glpA 7120204 glpA Escherichia fergusonii ATCC 35469 sn-glycerol-3-phosphate dehydrogenase subunit A YP_002382097.1 940972 R 585054 CDS YP_002382098.1 218548307 7120203 942870..944228 1 NC_011740.1 catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell; sn-glycerol-3-phosphate transporter 944228 glpT 7120203 glpT Escherichia fergusonii ATCC 35469 sn-glycerol-3-phosphate transporter YP_002382098.1 942870 D 585054 CDS YP_002382099.1 218548308 7120580 944176..945312 1 NC_011740.1 hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase 945312 glpQ 7120580 glpQ Escherichia fergusonii ATCC 35469 glycerophosphodiester phosphodiesterase YP_002382099.1 944176 D 585054 CDS YP_002382100.1 218548309 7120579 945464..946114 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 92165728, 1537798, 6087316; hypothetical protein 946114 inaA 7120579 inaA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382100.1 945464 D 585054 CDS YP_002382101.1 218548310 7120737 complement(946167..946421) 1 NC_011740.1 plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases; 2Fe-2S ferredoxin 946421 yfaE 7120737 yfaE Escherichia fergusonii ATCC 35469 2Fe-2S ferredoxin YP_002382101.1 946167 R 585054 CDS YP_002382102.1 218548311 7119803 complement(946421..947551) 1 NC_011740.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 947551 nrdB 7119803 nrdB Escherichia fergusonii ATCC 35469 ribonucleotide-diphosphate reductase subunit beta YP_002382102.1 946421 R 585054 CDS YP_002382103.1 218548312 7119659 complement(947614..949899) 1 NC_011740.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 949899 nrdA 7119659 nrdA Escherichia fergusonii ATCC 35469 ribonucleotide-diphosphate reductase subunit alpha YP_002382103.1 947614 R 585054 CDS YP_002382104.1 218548313 7119658 950582..954346 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15659678; Product type f : factor; adhesin 954346 yfaL 7119658 yfaL Escherichia fergusonii ATCC 35469 adhesin YP_002382104.1 950582 D 585054 CDS YP_002382105.1 218548314 7119804 complement(954487..955209) 1 NC_011740.1 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 955209 ubiG 7119804 ubiG Escherichia fergusonii ATCC 35469 3-demethylubiquinone-9 3-methyltransferase YP_002382105.1 954487 R 585054 CDS YP_002382106.1 218548315 7124072 955356..957992 1 NC_011740.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 957992 gyrA 7124072 gyrA Escherichia fergusonii ATCC 35469 DNA gyrase subunit A YP_002382106.1 955356 D 585054 CDS YP_002382107.1 218548316 7123191 complement(958103..959287) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 73032600, 87083402; Product type c : carrier; acetyl-CoA acetyltransferase 959287 atoB 7123191 atoB Escherichia fergusonii ATCC 35469 acetyl-CoA acetyltransferase YP_002382107.1 958103 R 585054 CDS YP_002382108.1 218548317 7121628 complement(959313..960635) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 73032600, 87083402; Product type t : transporter; short chain fatty acid transporter 960635 atoE 7121628 atoE Escherichia fergusonii ATCC 35469 short chain fatty acid transporter YP_002382108.1 959313 R 585054 CDS YP_002382109.1 218548318 7121631 complement(960632..961282) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 73032600, 87083402; Product type c : carrier; acetyl-CoA:acetoacetyl-CoA transferase subunit beta 961282 atoA 7121631 atoA Escherichia fergusonii ATCC 35469 acetyl-CoA:acetoacetyl-CoA transferase subunit beta YP_002382109.1 960632 R 585054 CDS YP_002382110.1 218548319 7121627 complement(961282..961944) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 73032600, 87083402; Product type c : carrier; acetyl-CoA:acetoacetyl-CoA transferase subunit alpha 961944 atoD 7121627 atoD Escherichia fergusonii ATCC 35469 acetyl-CoA:acetoacetyl-CoA transferase subunit alpha YP_002382110.1 961282 R 585054 CDS YP_002382111.1 218548320 7121630 complement(963531..965357) 1 NC_011740.1 with AtoC is a member of a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; sensory histidine kinase AtoS 965357 atoS 7121630 atoS Escherichia fergusonii ATCC 35469 sensory histidine kinase AtoS YP_002382111.1 963531 R 585054 CDS YP_002382112.1 218548321 7121632 965524..968373 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11758943, 12864862, 14651646, 20032358, 21450811, 88227838, 90130299, 92048476, 9209051, 2404948, 8366025; Product type r : regulator; hybrid sensory kinase in two-component regulatory system with RcsB and YojN 968373 rcsC 7121632 rcsC Escherichia fergusonii ATCC 35469 hybrid sensory kinase in two-component regulatory system with RcsB and YojN YP_002382112.1 965524 D 585054 CDS YP_002382113.1 218548322 7122354 complement(968457..969107) 1 NC_011740.1 two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF; transcriptional regulator RcsB 969107 rcsB 7122354 rcsB Escherichia fergusonii ATCC 35469 transcriptional regulator RcsB YP_002382113.1 968457 R 585054 CDS YP_002382114.1 218548323 7122353 complement(969124..971997) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11758943, 12864862, 21206231, 2404948, 7984428; Product type r : regulator; phosphotransfer intermediate protein in two-component regulatory system with RcsBC 971997 rcsD 7122353 rcsD Escherichia fergusonii ATCC 35469 phosphotransfer intermediate protein in two-component regulatory system with RcsBC YP_002382114.1 969124 R 585054 CDS YP_002382115.1 218548324 7120932 972532..973653 1 NC_011740.1 allows for ions and hydrophilic solutes to cross the outer membrane; outer membrane porin protein C 973653 ompC 7120932 ompC Escherichia fergusonii ATCC 35469 outer membrane porin protein C YP_002382115.1 972532 D 585054 CDS YP_002382116.1 218548325 7119692 973776..974831 1 NC_011740.1 catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway; thiamine biosynthesis lipoprotein ApbE 974831 yojL 7119692 yojL Escherichia fergusonii ATCC 35469 thiamine biosynthesis lipoprotein ApbE YP_002382116.1 973776 D 585054 CDS YP_002382117.1 218548326 7123915 974905..975969 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91073391, 93272965, 94252990; Product type r : regulator; bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase 975969 ada 7123915 ada Escherichia fergusonii ATCC 35469 bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase YP_002382117.1 974905 D 585054 CDS YP_002382118.1 218548327 7122271 975969..976619 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12226668, 12517444, 12862460, 14527653, 87057220, 88151899, 92017669, 3536913, 3887409, 7928996; Product type e : enzyme; oxidative demethylase 976619 alkB 7122271 alkB Escherichia fergusonii ATCC 35469 oxidative demethylase YP_002382118.1 975969 D 585054 CDS YP_002382119.1 218548328 7123458 976695..978338 1 NC_011740.1 efflux pump for the antibacterial peptide microcin J25; multidrug transporter membrane protein/ATP-binding protein 978338 yojI 7123458 yojI Escherichia fergusonii ATCC 35469 multidrug transporter membrane protein/ATP-binding protein YP_002382119.1 976695 D 585054 CDS YP_002382120.1 218548329 7121737 978553..980199 1 NC_011740.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase 980199 mqo 7121737 mqo Escherichia fergusonii ATCC 35469 malate:quinone oxidoreductase YP_002382120.1 978553 D 585054 CDS YP_002382121.1 218548330 7120962 complement(980282..981004) 1 NC_011740.1 similar to ATP-binding component of ABC transporters; glutamine ABC transporter ATP-binding protein 981004 glnQ 7120962 glnQ Escherichia fergusonii ATCC 35469 glutamine ABC transporter ATP-binding protein YP_002382121.1 980282 R 585054 CDS YP_002382122.1 218548331 7120201 complement(981001..981660) 1 NC_011740.1 similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine; glutamine ABC transporter permease 981660 glnP 7120201 glnP Escherichia fergusonii ATCC 35469 glutamine ABC transporter permease YP_002382122.1 981001 R 585054 CDS YP_002382123.1 218548332 7120200 complement(981754..982500) 1 NC_011740.1 similar to periplasmic-binding component of ABC transporters; glutamine ABC transporter periplasmic protein 982500 glnH 7120200 glnH Escherichia fergusonii ATCC 35469 glutamine ABC transporter periplasmic protein YP_002382123.1 981754 R 585054 CDS YP_002382124.1 218548333 7123120 complement(982907..983410) 1 NC_011740.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps 983410 dps 7123120 dps Escherichia fergusonii ATCC 35469 DNA starvation/stationary phase protection protein Dps YP_002382124.1 982907 R 585054 CDS YP_002382125.1 218548334 7122920 complement(983699..984586) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12648727, 8021175; Product type t : transporter; threonine and homoserine efflux system 984586 rhtA 7122920 rhtA Escherichia fergusonii ATCC 35469 threonine and homoserine efflux system YP_002382125.1 983699 R 585054 CDS YP_002382126.1 218548335 7121402 984937..985452 1 NC_011740.1 OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; outer membrane protein X 985452 ompX 7121402 ompX Escherichia fergusonii ATCC 35469 outer membrane protein X YP_002382126.1 984937 D 585054 CDS YP_002382127.1 218548336 7119695 complement(985520..987127) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16514146; Product type pe : enzyme; hypothetical protein 987127 ybiP 7119695 ybiP Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382127.1 985520 R 585054 CDS YP_002382128.1 218548337 7123426 complement(987371..987499) 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 987499 7123426 EFER_0959 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382128.1 987371 R 585054 CDS YP_002382129.1 218548338 7123279 987685..988152 1 NC_011740.1 Transcriptional regulator that represses the manganese transporter MntH when manganese is present; manganese transport regulator MntR 988152 mntR 7123279 mntR Escherichia fergusonii ATCC 35469 manganese transport regulator MntR YP_002382129.1 987685 D 585054 CDS YP_002382130.1 218548339 7120945 988149..989264 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter 989264 ybiR 7120945 ybiR Escherichia fergusonii ATCC 35469 transporter YP_002382130.1 988149 D 585054 CDS YP_002382131.1 218548340 7123427 complement(989324..990244) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10493123, 9298646; hypothetical protein 990244 ybiS 7123427 ybiS Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382131.1 989324 R 585054 CDS YP_002382132.1 218548341 7122101 990463..992055 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11916677; Product type pt : transporter; ABC transporter ATP-binding protein 992055 ybiT 7122101 ybiT Escherichia fergusonii ATCC 35469 ABC transporter ATP-binding protein YP_002382132.1 990463 D 585054 CDS YP_002382133.1 218548342 7123979 complement(992254..993069) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15657928; Product type e : enzyme; type II HAD phosphatase 993069 ybiV 7123979 ybiV Escherichia fergusonii ATCC 35469 type II HAD phosphatase YP_002382133.1 992254 R 585054 CDS YP_002382134.1 218548343 7122102 complement(993215..995647) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16218870; Product type pe : enzyme; glycyl radical cofactor protein 995647 ybiW 7122102 ybiW Escherichia fergusonii ATCC 35469 glycyl radical cofactor protein YP_002382134.1 993215 R 585054 CDS YP_002382135.1 218548344 7122103 complement(995653..996579) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15581584; Product type pe : enzyme; AdoMet-dependent glycyl radical activating enzyme 996579 ybiY 7122103 ybiY Escherichia fergusonii ATCC 35469 AdoMet-dependent glycyl radical activating enzyme YP_002382135.1 995653 R 585054 CDS YP_002382136.1 218548345 7122105 996683..997345 1 NC_011740.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 997345 fsaA 7122105 fsaA Escherichia fergusonii ATCC 35469 fructose-6-phosphate aldolase YP_002382136.1 996683 D 585054 CDS YP_002382137.1 218548346 7124144 complement(997432..998181) 1 NC_011740.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB 998181 moeB 7124144 moeB Escherichia fergusonii ATCC 35469 molybdopterin biosynthesis protein MoeB YP_002382137.1 997432 R 585054 CDS YP_002382138.1 218548347 7123781 complement(998181..999416) 1 NC_011740.1 is involved in the formation of active molybdenum cofactor and the chelation of molybdenum; molybdopterin biosynthesis protein MoeA 999416 moeA 7123781 moeA Escherichia fergusonii ATCC 35469 molybdopterin biosynthesis protein MoeA YP_002382138.1 998181 R 585054 CDS YP_002382139.1 218548348 7120954 999629..1001521 1 NC_011740.1 with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains; glutathione transporter ATP-binding protein 1001521 yliA 7120954 yliA Escherichia fergusonii ATCC 35469 glutathione transporter ATP-binding protein YP_002382139.1 999629 D 585054 CDS YP_002382140.1 218548349 7122044 1001548..1003086 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 17366475; Product type pt : transporter; peptide ABC transporter substrate-binding protein 1003086 yliB 7122044 yliB Escherichia fergusonii ATCC 35469 peptide ABC transporter substrate-binding protein YP_002382140.1 1001548 D 585054 CDS YP_002382141.1 218548350 7122045 1003106..1004026 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; peptide ABC transporter permease 1004026 yliC 7122045 yliC Escherichia fergusonii ATCC 35469 peptide ABC transporter permease YP_002382141.1 1003106 D 585054 CDS YP_002382142.1 218548351 7122046 1004029..1004940 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; peptide ABC transporter permease 1004940 yliD 7122046 yliD Escherichia fergusonii ATCC 35469 peptide ABC transporter permease YP_002382142.1 1004029 D 585054 CDS YP_002382143.1 218548352 7122047 1005071..1007419 1 NC_011740.1 hypothetical protein 1007419 7122047 EFER_0974 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382143.1 1005071 D 585054 CDS YP_002382144.1 218548353 7120252 1007429..1008757 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; diguanylate cyclase 1008757 yliF 7120252 yliF Escherichia fergusonii ATCC 35469 diguanylate cyclase YP_002382144.1 1007429 D 585054 CDS YP_002382145.1 218548354 7122048 complement(1008798..1010123) 1 NC_011740.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; 30S ribosomal protein S12 methylthiotransferase 1010123 rimO 7122048 rimO Escherichia fergusonii ATCC 35469 30S ribosomal protein S12 methylthiotransferase YP_002382145.1 1008798 R 585054 CDS YP_002382146.1 218548355 7123416 1010351..1010734 1 NC_011740.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssR 1010734 bssR 7123416 bssR Escherichia fergusonii ATCC 35469 biofilm formation regulatory protein BssR YP_002382146.1 1010351 D 585054 CDS YP_002382147.1 218548356 7121678 1010836..1011948 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16522795, 16864586; Product type e : enzyme; PQQ-dependent aldose sugar dehydrogenase 1011948 yliI 7121678 yliI Escherichia fergusonii ATCC 35469 PQQ-dependent aldose sugar dehydrogenase YP_002382147.1 1010836 D 585054 CDS YP_002382148.1 218548357 7122050 complement(1011953..1012585) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; glutathione S-transferase 1012585 yliJ 7122050 yliJ Escherichia fergusonii ATCC 35469 glutathione S-transferase YP_002382148.1 1011953 R 585054 CDS YP_002382149.1 218548358 7122051 1012826..1014028 1 NC_011740.1 penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 1014028 dacC 7122051 dacC Escherichia fergusonii ATCC 35469 D-alanyl-D-alanine carboxypeptidase YP_002382149.1 1012826 D 585054 CDS YP_002382150.1 218548359 7122862 complement(1014076..1014873) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89231635, 89336786, 92231401, 2994018; Product type r : regulator; DNA-binding transcriptional repressor DeoR 1014873 deoR 7122862 deoR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional repressor DeoR YP_002382150.1 1014076 R 585054 CDS YP_002382151.1 218548360 7122890 complement(1014906..1015514) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15778224; Product type e : enzyme; undecaprenyl pyrophosphate phosphatase 1015514 ybjG 7122890 ybjG Escherichia fergusonii ATCC 35469 undecaprenyl pyrophosphate phosphatase YP_002382151.1 1014906 R 585054 CDS YP_002382152.1 218548361 7122107 1015799..1017031 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10022825, 12578981, 14688269, 21217867, 21450803, 9079913, 9644262, 99030337, 8655497; Product type t : transporter; multidrug efflux system protein 1017031 cmr 7122107 cmr Escherichia fergusonii ATCC 35469 multidrug efflux system protein YP_002382152.1 1015799 D 585054 CDS YP_002382153.1 218548362 7120907 complement(1017072..1017350) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1017350 ybjH 7120907 ybjH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382153.1 1017072 R 585054 CDS YP_002382154.1 218548363 7122108 complement(1017454..1018269) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15808744; Product type pe : enzyme; phosphatase 1018269 ybjI 7122108 ybjI Escherichia fergusonii ATCC 35469 phosphatase YP_002382154.1 1017454 R 585054 CDS YP_002382155.1 218548364 7122109 complement(1018269..1019477) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter 1019477 ybjJ 7122109 ybjJ Escherichia fergusonii ATCC 35469 transporter YP_002382155.1 1018269 R 585054 CDS YP_002382156.1 218548365 7122110 1019565..1020104 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator 1020104 ybjK 7122110 ybjK Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YP_002382156.1 1019565 D 585054 CDS YP_002382157.1 218548366 7122111 1020204..1020422 1 NC_011740.1 hypothetical protein 1020422 7122111 EFER_0988 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382157.1 1020204 D 585054 CDS YP_002382158.1 218548367 7123129 complement(1020585..1020824) 1 NC_011740.1 hypothetical protein 1020824 7123129 EFER_0989 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382158.1 1020585 R 585054 CDS YP_002382159.1 218548368 7121171 complement(1021037..1022722) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; hypothetical protein 1022722 ybjL 7121171 ybjL Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382159.1 1021037 R 585054 CDS YP_002382160.1 218548369 7122112 1022991..1023380 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type pm : membrane component; hypothetical protein 1023380 ybjM 7122112 ybjM Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382160.1 1022991 D 585054 CDS YP_002382161.1 218548370 7122113 1023545..1024267 1 NC_011740.1 NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; nitroreductase A 1024267 nfsA 7122113 nfsA Escherichia fergusonii ATCC 35469 nitroreductase A YP_002382161.1 1023545 D 585054 CDS YP_002382162.1 218548371 7120689 1024317..1025219 1 NC_011740.1 responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6; ribosomal protein S6 modification protein 1025219 rimK 7120689 rimK Escherichia fergusonii ATCC 35469 ribosomal protein S6 modification protein YP_002382162.1 1024317 D 585054 CDS YP_002382163.1 218548372 7121413 1025308..1025784 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1025784 ybjN 7121413 ybjN Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382163.1 1025308 D 585054 CDS YP_002382164.1 218548373 7122114 1026136..1027248 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93106992, 9651355, 9298646, 8416922; Product type t : transporter; putrescine ABC transporter periplasmic-binding protein 1027248 potF 7122114 potF Escherichia fergusonii ATCC 35469 putrescine ABC transporter periplasmic-binding protein YP_002382164.1 1026136 D 585054 CDS YP_002382165.1 218548374 7120103 1027343..1028476 1 NC_011740.1 part of the PotFGHI ATP-dependent putrescine transporter; putrescine ABC transporter ATP-binding protein 1028476 potG 7120103 potG Escherichia fergusonii ATCC 35469 putrescine ABC transporter ATP-binding protein YP_002382165.1 1027343 D 585054 CDS YP_002382166.1 218548375 7123103 1028486..1029439 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93106992; Product type t : transporter; putrescine ABC transporter membrane protein 1029439 potH 7123103 potH Escherichia fergusonii ATCC 35469 putrescine ABC transporter membrane protein YP_002382166.1 1028486 D 585054 CDS YP_002382167.1 218548376 7120104 1029436..1030281 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93106992; Product type t : transporter; putrescine ABC transporter membrane protein 1030281 potI 7120104 potI Escherichia fergusonii ATCC 35469 putrescine ABC transporter membrane protein YP_002382167.1 1029436 D 585054 CDS YP_002382168.1 218548377 7123104 1030341..1030829 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1030829 ybjO 7123104 ybjO Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382168.1 1030341 D 585054 CDS YP_002382169.1 218548378 7122115 1030870..1031997 1 NC_011740.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase 1031997 rumB 7122115 rumB Escherichia fergusonii ATCC 35469 23S rRNA methyluridine methyltransferase YP_002382169.1 1030870 D 585054 CDS YP_002382170.1 218548379 7121164 complement(1032026..1032757) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93273744, 9298646, 9600841, 8801422; Product type t : transporter; arginine ABC transporter substrate-binding protein 1032757 artJ 7121164 artJ Escherichia fergusonii ATCC 35469 arginine ABC transporter substrate-binding protein YP_002382170.1 1032026 R 585054 CDS YP_002382171.1 218548380 7120557 complement(1032984..1033652) 1 NC_011740.1 with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease subunit ArtM 1033652 artM 7120557 artM Escherichia fergusonii ATCC 35469 arginine transporter permease subunit ArtM YP_002382171.1 1032984 R 585054 CDS YP_002382172.1 218548381 7120559 complement(1033652..1034368) 1 NC_011740.1 with ArtPMJI transports arginine across the inner membrane; arginine transporter permease subunit ArtQ 1034368 artQ 7120559 artQ Escherichia fergusonii ATCC 35469 arginine transporter permease subunit ArtQ YP_002382172.1 1033652 R 585054 CDS YP_002382173.1 218548382 7120560 complement(1034375..1035106) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93273744, 9298646, 9600841, 8801422, 9740056; Product type t : transporter; arginine ABC transporter substrate-binding protein 1035106 artI 7120560 artI Escherichia fergusonii ATCC 35469 arginine ABC transporter substrate-binding protein YP_002382173.1 1034375 R 585054 CDS YP_002382174.1 218548383 7120556 complement(1035124..1035852) 1 NC_011740.1 With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit 1035852 artP 7120556 artP Escherichia fergusonii ATCC 35469 arginine transporter ATP-binding subunit YP_002382174.1 1035124 R 585054 CDS YP_002382175.1 218548384 7123180 complement(1036070..1036585) 1 NC_011740.1 induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS; lipoprotein 1036585 ybjP 7123180 ybjP Escherichia fergusonii ATCC 35469 lipoprotein YP_002382175.1 1036070 R 585054 CDS YP_002382176.1 218548385 7122116 1036711..1037034 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1037034 ybjQ 7122116 ybjQ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382176.1 1036711 D 585054 CDS YP_002382177.1 218548386 7123428 1037031..1037861 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; cell wall amidase and lipoprotein 1037861 ybjR 7123428 ybjR Escherichia fergusonii ATCC 35469 cell wall amidase and lipoprotein YP_002382177.1 1037031 D 585054 CDS YP_002382178.1 218548387 7123429 complement(1037858..1038871) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; NAD(P)H:quinone oxidoreductase 1038871 ybjS 7123429 ybjS Escherichia fergusonii ATCC 35469 NAD(P)H:quinone oxidoreductase YP_002382178.1 1037858 R 585054 CDS YP_002382179.1 218548388 7122117 complement(1038970..1040400) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1040400 ybjT 7122117 ybjT Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382179.1 1038970 R 585054 CDS YP_002382180.1 218548389 7122118 complement(1040411..1041412) 1 NC_011740.1 low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine; L-threonine aldolase 1041412 ltaE 7122118 ltaE Escherichia fergusonii ATCC 35469 L-threonine aldolase YP_002382180.1 1040411 R 585054 CDS YP_002382181.1 218548390 7123283 complement(1041449..1043167) 1 NC_011740.1 catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase 1043167 poxB 7123283 poxB Escherichia fergusonii ATCC 35469 pyruvate dehydrogenase YP_002382181.1 1041449 R 585054 CDS YP_002382182.1 218548391 7120105 1043319..1043753 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1043753 7120105 EFER_1016 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382182.1 1043319 D 585054 CDS YP_002382183.1 218548392 7123669 complement(1043811..1044779) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20117674; Product type e : enzyme; HCP oxidoreductase 1044779 hcr 7123669 hcr Escherichia fergusonii ATCC 35469 HCP oxidoreductase YP_002382183.1 1043811 R 585054 CDS YP_002382184.1 218548393 7120631 complement(1044791..1046443) 1 NC_011740.1 catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase 1046443 hcp 7120631 hcp Escherichia fergusonii ATCC 35469 hydroxylamine reductase YP_002382184.1 1044791 R 585054 CDS YP_002382185.1 218548394 7120630 complement(1046587..1047486) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter 1047486 ybjE 7120630 ybjE Escherichia fergusonii ATCC 35469 transporter YP_002382185.1 1046587 R 585054 CDS YP_002382186.1 218548395 7123980 1047825..1048850 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transposase, IS110 family 1048850 7123980 EFER_1020 Escherichia fergusonii ATCC 35469 transposase, IS110 family YP_002382186.1 1047825 D 585054 CDS YP_002382187.1 218548396 7120254 1049101..1049277 1 NC_011740.1 hypothetical protein 1049277 7120254 EFER_1021 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382187.1 1049101 D 585054 CDS YP_002382188.1 218548397 7120255 complement(1049368..1050063) 1 NC_011740.1 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; aquaporin Z 1050063 aqpZ 7120255 aqpZ Escherichia fergusonii ATCC 35469 aquaporin Z YP_002382188.1 1049368 R 585054 CDS YP_002382189.1 218548398 7120526 1050485..1052143 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1052143 ybjD 7120526 ybjD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382189.1 1050485 D 585054 CDS YP_002382190.1 218548399 7122106 complement(1052140..1053147) 1 NC_011740.1 hypothetical protein 1053147 7122106 EFER_1024 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382190.1 1052140 R 585054 CDS YP_002382191.1 218548400 7120256 complement(1053093..1053218) 1 NC_011740.1 hypothetical protein 1053218 7120256 EFER_1025 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382191.1 1053093 R 585054 CDS YP_002382192.1 218548401 7120257 1053252..1054367 1 NC_011740.1 confers macrolide resistance via active drug efflux; macrolide transporter subunit MacA 1054367 macA 7120257 macA Escherichia fergusonii ATCC 35469 macrolide transporter subunit MacA YP_002382192.1 1053252 D 585054 CDS YP_002382193.1 218548402 7121219 1054364..1056310 1 NC_011740.1 with MacA is involved in the export of macrolide; macrolide transporter ATP-binding /permease 1056310 macB 7121219 macB Escherichia fergusonii ATCC 35469 macrolide transporter ATP-binding /permease YP_002382193.1 1054364 D 585054 CDS YP_002382194.1 218548403 7121220 complement(1056531..1056752) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21160192, 94293754, 97405911, 1622933, 2186030, 9868784; Product type f : factor; cold shock protein-like protein 1056752 cspD 7121220 cspD Escherichia fergusonii ATCC 35469 cold shock protein-like protein YP_002382194.1 1056531 R 585054 CDS YP_002382195.1 218548404 7122820 1057075..1057395 1 NC_011740.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 1057395 clpS 7122820 clpS Escherichia fergusonii ATCC 35469 ATP-dependent Clp protease adaptor protein ClpS YP_002382195.1 1057075 D 585054 CDS YP_002382196.1 218548405 7123240 1057411..1059705 1 NC_011740.1 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; ATP-dependent Clp protease ATP-binding subunit 1059705 clpA 7123240 clpA Escherichia fergusonii ATCC 35469 ATP-dependent Clp protease ATP-binding subunit YP_002382196.1 1057411 D 585054 CDS YP_002382197.1 218548406 7120081 complement(1060450..1060668) 1 NC_011740.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 1060668 infA 7120081 infA Escherichia fergusonii ATCC 35469 translation initiation factor IF-1 YP_002382197.1 1060450 R 585054 CDS YP_002382198.1 218548407 7123212 complement(1060953..1061657) 1 NC_011740.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase 1061657 aat 7123212 aat Escherichia fergusonii ATCC 35469 leucyl/phenylalanyl-tRNA--protein transferase YP_002382198.1 1060953 R 585054 CDS YP_002382199.1 218548408 7122252 complement(1061699..1063420) 1 NC_011740.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 1063420 cydC 7122252 cydC Escherichia fergusonii ATCC 35469 cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_002382199.1 1061699 R 585054 CDS YP_002382200.1 218548409 7123542 complement(1063421..1065187) 1 NC_011740.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 1065187 cydD 7123542 cydD Escherichia fergusonii ATCC 35469 cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_002382200.1 1063421 R 585054 CDS YP_002382201.1 218548410 7122841 complement(1065310..1066275) 1 NC_011740.1 catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; thioredoxin reductase 1066275 trxB 7122841 trxB Escherichia fergusonii ATCC 35469 thioredoxin reductase YP_002382201.1 1065310 R 585054 CDS YP_002382202.1 218548411 7122172 1066808..1067302 1 NC_011740.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 1067302 lrp 7122172 lrp Escherichia fergusonii ATCC 35469 leucine-responsive transcriptional regulator YP_002382202.1 1066808 D 585054 CDS YP_002382203.1 218548412 7121206 1067437..1071282 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10027974, 11864592, 12034757, 99047597, 10922461, 11703663, 11832210, 11948172, 7592387; Product type cp : cell process; DNA-binding membrane protein 1071282 ftsK 7121206 ftsK Escherichia fergusonii ATCC 35469 DNA-binding membrane protein YP_002382203.1 1067437 D 585054 CDS YP_002382204.1 218548413 7123113 1071438..1072052 1 NC_011740.1 participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 1072052 lolA 7123113 lolA Escherichia fergusonii ATCC 35469 outer-membrane lipoprotein carrier protein YP_002382204.1 1071438 D 585054 CDS YP_002382205.1 218548414 7123763 1072063..1073406 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7567469, 7628437, 11459952, 11029431; Product type cp : cell process; recombination factor protein RarA 1073406 ycaJ 7123763 ycaJ Escherichia fergusonii ATCC 35469 recombination factor protein RarA YP_002382205.1 1072063 D 585054 CDS YP_002382206.1 218548415 7123981 1073497..1074789 1 NC_011740.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 1074789 serS 7123981 serS Escherichia fergusonii ATCC 35469 seryl-tRNA synthetase YP_002382206.1 1073497 D 585054 CDS YP_002382207.1 218548416 7121771 complement(1074847..1075473) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9782055, 3062312, 11714269; Product type pe : enzyme; hydrolase 1075473 ycaC 7121771 ycaC Escherichia fergusonii ATCC 35469 hydrolase YP_002382207.1 1074847 R 585054 CDS YP_002382208.1 218548417 7122119 1075786..1076934 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; MFS family transporter protein 1076934 ycaD 7122119 ycaD Escherichia fergusonii ATCC 35469 MFS family transporter protein YP_002382208.1 1075786 D 585054 CDS YP_002382209.1 218548418 7122120 1077142..1078572 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15380559; Product type pt : transporter; transporter 1078572 ycaM 7122120 ycaM Escherichia fergusonii ATCC 35469 transporter YP_002382209.1 1077142 D 585054 CDS YP_002382210.1 218548419 7122121 complement(1078782..1079522) 1 NC_011740.1 activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 1079522 pflA 7122121 pflA Escherichia fergusonii ATCC 35469 pyruvate formate lyase-activating enzyme 1 YP_002382210.1 1078782 R 585054 CDS YP_002382211.1 218548420 7123504 complement(1079715..1081997) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91064082, 92276323, 10504733, 1310545, 2651404, 3053170, 9629924; Product type e : enzyme; pyruvate formate lyase I 1081997 pflB 7123504 pflB Escherichia fergusonii ATCC 35469 pyruvate formate lyase I YP_002382211.1 1079715 R 585054 CDS YP_002382212.1 218548421 7122583 complement(1082053..1082910) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94293770, 2651404; Product type t : transporter; formate transporter 1082910 focA 7122583 focA Escherichia fergusonii ATCC 35469 formate transporter YP_002382212.1 1082053 R 585054 CDS YP_002382213.1 218548422 7123568 complement(1083315..1085075) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1085075 ycaO 7123568 ycaO Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382213.1 1083315 R 585054 CDS YP_002382214.1 218548423 7122122 1085205..1085897 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1085897 ycaP 7122122 ycaP Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382214.1 1085205 D 585054 CDS YP_002382215.1 218548424 7123982 1086087..1087175 1 NC_011740.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 1087175 serC 7123982 serC Escherichia fergusonii ATCC 35469 phosphoserine aminotransferase YP_002382215.1 1086087 D 585054 CDS YP_002382216.1 218548425 7121770 1087218..1088522 1 NC_011740.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1088522 aroA 7121770 aroA Escherichia fergusonii ATCC 35469 3-phosphoshikimate 1-carboxyvinyltransferase YP_002382216.1 1087218 D 585054 CDS YP_002382217.1 218548426 7123716 1088709..1089392 1 NC_011740.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 1089392 cmk 7123716 cmk Escherichia fergusonii ATCC 35469 cytidylate kinase YP_002382217.1 1088709 D 585054 CDS YP_002382218.1 218548427 7120906 1089503..1091176 1 NC_011740.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1091176 rpsA 7120906 rpsA Escherichia fergusonii ATCC 35469 30S ribosomal protein S1 YP_002382218.1 1089503 D 585054 CDS YP_002382219.1 218548428 7121126 1091336..1091620 1 NC_011740.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 1091620 ihfB 7121126 ihfB Escherichia fergusonii ATCC 35469 integration host factor subunit beta YP_002382219.1 1091336 D 585054 CDS YP_002382220.1 218548429 7120725 1091823..1094087 1 NC_011740.1 hypothetical protein 1094087 7120725 EFER_1057 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382220.1 1091823 D 585054 CDS YP_002382221.1 218548430 7120259 1094124..1095872 1 NC_011740.1 involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding protein/permease 1095872 msbA 7120259 msbA Escherichia fergusonii ATCC 35469 lipid transporter ATP-binding protein/permease YP_002382221.1 1094124 D 585054 CDS YP_002382222.1 218548431 7120970 1095869..1096855 1 NC_011740.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 1096855 lpxK 7120970 lpxK Escherichia fergusonii ATCC 35469 tetraacyldisaccharide 4'-kinase YP_002382222.1 1095869 D 585054 CDS YP_002382223.1 218548432 7123827 1096892..1098124 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1098124 ycaQ 7123827 ycaQ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382223.1 1096892 D 585054 CDS YP_002382224.1 218548433 7122123 1098177..1098359 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1098359 ycaR 7122123 ycaR Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382224.1 1098177 D 585054 CDS YP_002382225.1 218548434 7122124 1098356..1099102 1 NC_011740.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 1099102 kdsB 7122124 kdsB Escherichia fergusonii ATCC 35469 3-deoxy-manno-octulosonate cytidylyltransferase YP_002382225.1 1098356 D 585054 CDS YP_002382226.1 218548435 7120809 1099255..1100148 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1100148 ycbJ 7120809 ycbJ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382226.1 1099255 D 585054 CDS YP_002382227.1 218548436 7119899 complement(1100125..1100904) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1100904 ycbC 7119899 ycbC Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382227.1 1100125 R 585054 CDS YP_002382228.1 218548437 7123983 1101040..1101825 1 NC_011740.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA; metallothionein SmtA 1101825 smtA 7123983 smtA Escherichia fergusonii ATCC 35469 metallothionein SmtA YP_002382228.1 1101040 D 585054 CDS YP_002382229.1 218548438 7121796 1101822..1103144 1 NC_011740.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 1103144 mukF 7121796 mukF Escherichia fergusonii ATCC 35469 condesin subunit F YP_002382229.1 1101822 D 585054 CDS YP_002382230.1 218548439 7120644 1103152..1103829 1 NC_011740.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 1103829 mukE 7120644 mukE Escherichia fergusonii ATCC 35469 condesin subunit E YP_002382230.1 1103152 D 585054 CDS YP_002382231.1 218548440 7120643 1103829..1108289 1 NC_011740.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 1108289 mukB 7120643 mukB Escherichia fergusonii ATCC 35469 cell division protein MukB YP_002382231.1 1103829 D 585054 CDS YP_002382232.1 218548441 7120642 1108532..1110379 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 1110379 ycbB 7120642 ycbB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382232.1 1108532 D 585054 CDS YP_002382233.1 218548442 7122125 1110551..1111111 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1111111 ycbK 7122125 ycbK Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382233.1 1110551 D 585054 CDS YP_002382234.1 218548443 7119900 1111138..1111785 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14529289; Product type pe : enzyme; metal-binding hydrolase 1111785 ycbL 7119900 ycbL Escherichia fergusonii ATCC 35469 metal-binding hydrolase YP_002382234.1 1111138 D 585054 CDS YP_002382235.1 218548444 7119901 complement(1111834..1113024) 1 NC_011740.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 1113024 aspC 7119901 aspC Escherichia fergusonii ATCC 35469 aromatic amino acid aminotransferase YP_002382235.1 1111834 R 585054 CDS YP_002382236.1 218548445 7120571 complement(1113208..1114278) 1 NC_011740.1 outer membrane porin F; 1a; Ia; b; outer membrane protein F 1114278 ompF 7120571 ompF Escherichia fergusonii ATCC 35469 outer membrane protein F YP_002382236.1 1113208 R 585054 CDS YP_002382237.1 218548446 7119693 complement(1114888..1116288) 1 NC_011740.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 1116288 asnC 7119693 asnC Escherichia fergusonii ATCC 35469 asparaginyl-tRNA synthetase YP_002382237.1 1114888 R 585054 CDS YP_002382238.1 218548447 7123182 complement(1116454..1117656) 1 NC_011740.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 1117656 pncB 7123182 pncB Escherichia fergusonii ATCC 35469 nicotinate phosphoribosyltransferase YP_002382238.1 1116454 R 585054 CDS YP_002382239.1 218548448 7120092 1117922..1120534 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21101837, 86164315, 87163509, 2436977, 3018440; Product type e : enzyme; aminopeptidase N 1120534 pepN 7120092 pepN Escherichia fergusonii ATCC 35469 aminopeptidase N YP_002382239.1 1117922 D 585054 CDS YP_002382240.1 218548449 7123503 complement(1120577..1121344) 1 NC_011740.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease; aliphatic sulfonates transport ATP-binding subunit 1121344 ssuB 7123503 ssuB Escherichia fergusonii ATCC 35469 aliphatic sulfonates transport ATP-binding subunit YP_002382240.1 1120577 R 585054 CDS YP_002382241.1 218548450 7123952 complement(1121341..1122132) 1 NC_011740.1 part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter permease 1122132 ssuC 7123952 ssuC Escherichia fergusonii ATCC 35469 alkanesulfonate transporter permease YP_002382241.1 1121341 R 585054 CDS YP_002382242.1 218548451 7121948 complement(1122144..1123289) 1 NC_011740.1 catalyzes the release of sulfite from alkanesulfonates; alkanesulfonate monooxygenase 1123289 ssuD 7121948 ssuD Escherichia fergusonii ATCC 35469 alkanesulfonate monooxygenase YP_002382242.1 1122144 R 585054 CDS YP_002382243.1 218548452 7121949 complement(1123286..1124245) 1 NC_011740.1 part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter substrate-binding subunit 1124245 ssuA 7121949 ssuA Escherichia fergusonii ATCC 35469 alkanesulfonate transporter substrate-binding subunit YP_002382243.1 1123286 R 585054 CDS YP_002382244.1 218548453 7121947 complement(1124238..1124813) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20245523, 99410391, 99436146, 8774726; Product type e : enzyme; NAD(P)H-dependent FMN reductase 1124813 ssuE 7121947 ssuE Escherichia fergusonii ATCC 35469 NAD(P)H-dependent FMN reductase YP_002382244.1 1124238 R 585054 CDS YP_002382245.1 218548454 7121950 1125050..1126060 1 NC_011740.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 1126060 pyrD 7121950 pyrD Escherichia fergusonii ATCC 35469 dihydroorotate dehydrogenase 2 YP_002382245.1 1125050 D 585054 CDS YP_002382246.1 218548455 7122334 1126234..1126776 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1126776 ycbW 7122334 ycbW Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382246.1 1126234 D 585054 CDS YP_002382247.1 218548456 7119902 complement(1126773..1127882) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1327782; Product type pe : enzyme; 2Fe-2S cluster-containing protein 1127882 ycbX 7119902 ycbX Escherichia fergusonii ATCC 35469 2Fe-2S cluster-containing protein YP_002382247.1 1126773 R 585054 CDS YP_002382248.1 218548457 7119903 1127980..1130088 1 NC_011740.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 1130088 rlmL 7119903 rlmL Escherichia fergusonii ATCC 35469 23S rRNA m(2)G2445 methyltransferase YP_002382248.1 1127980 D 585054 CDS YP_002382249.1 218548458 7119904 1130100..1132007 1 NC_011740.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase 1132007 uup 7119904 uup Escherichia fergusonii ATCC 35469 ABC transporter ATPase YP_002382249.1 1130100 D 585054 CDS YP_002382250.1 218548459 7123512 1132137..1133384 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95270582; Product type cp : cell process; paraquat-inducible membrane protein A 1133384 pqiA 7123512 pqiA Escherichia fergusonii ATCC 35469 paraquat-inducible membrane protein A YP_002382250.1 1132137 D 585054 CDS YP_002382251.1 218548460 7120119 1133389..1135029 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95270582; Product type cp : cell process; paraquat-inducible protein B 1135029 pqiB 7120119 pqiB Escherichia fergusonii ATCC 35469 paraquat-inducible protein B YP_002382251.1 1133389 D 585054 CDS YP_002382252.1 218548461 7120120 1135041..1135589 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1135589 ymbA 7120120 ymbA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382252.1 1135041 D 585054 CDS YP_002382253.1 218548462 7122052 1135845..1136012 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1101029, 90207255, 2832401, 8440252; Product type f : factor; ribosome modulation factor 1136012 rmf 7122052 rmf Escherichia fergusonii ATCC 35469 ribosome modulation factor YP_002382253.1 1135845 D 585054 CDS YP_002382254.1 218548463 7121419 complement(1136079..1136597) 1 NC_011740.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase 1136597 fabA 7121419 fabA Escherichia fergusonii ATCC 35469 3-hydroxydecanoyl-ACP dehydratase YP_002382254.1 1136079 R 585054 CDS YP_002382255.1 218548464 7119978 complement(1136666..1138426) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; ATP-dependent protease 1138426 ycbZ 7119978 ycbZ Escherichia fergusonii ATCC 35469 ATP-dependent protease YP_002382255.1 1136666 R 585054 CDS YP_002382256.1 218548465 7119905 1138611..1139066 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1139066 ycbG 7119905 ycbG Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382256.1 1138611 D 585054 CDS YP_002382257.1 218548466 7121751 complement(1139121..1140248) 1 NC_011740.1 OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; outer membrane protein A 1140248 ompA 7121751 ompA Escherichia fergusonii ATCC 35469 outer membrane protein A YP_002382257.1 1139121 R 585054 CDS YP_002382258.1 218548467 7120759 complement(1140533..1141042) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10368140, 91072263, 93163041, 98348458, 3297925, 6253901, 6306396; Product type cp : cell process; SOS cell division inhibitor 1141042 sulA 7120759 sulA Escherichia fergusonii ATCC 35469 SOS cell division inhibitor YP_002382258.1 1140533 R 585054 CDS YP_002382259.1 218548468 7121966 1141259..1141888 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1141888 7121966 EFER_1096 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382259.1 1141259 D 585054 CDS YP_002382260.1 218548469 7120260 complement(1141851..1144064) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1144064 yccS 7120260 yccS Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382260.1 1141851 R 585054 CDS YP_002382261.1 218548470 7119908 complement(1144024..1144470) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1144470 yccF 7119908 yccF Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382261.1 1144024 R 585054 CDS YP_002382262.1 218548471 7123071 1144593..1146647 1 NC_011740.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand; DNA helicase IV 1146647 helD 7123071 helD Escherichia fergusonii ATCC 35469 DNA helicase IV YP_002382262.1 1144593 D 585054 CDS YP_002382263.1 218548472 7120636 complement(1146679..1147137) 1 NC_011740.1 catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase 1147137 mgsA 7120636 mgsA Escherichia fergusonii ATCC 35469 methylglyoxal synthase YP_002382263.1 1146679 R 585054 CDS YP_002382264.1 218548473 7123778 complement(1147233..1147895) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1147895 yccT 7123778 yccT Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382264.1 1147233 R 585054 CDS YP_002382265.1 218548474 7123072 1148068..1148481 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; CoA-binding protein 1148481 yccU 7123072 yccU Escherichia fergusonii ATCC 35469 CoA-binding protein YP_002382265.1 1148068 D 585054 CDS YP_002382266.1 218548475 7119909 complement(1148528..1148845) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12700277, 15569148; Product type f : factor; heat shock protein HspQ 1148845 yccV 7119909 yccV Escherichia fergusonii ATCC 35469 heat shock protein HspQ YP_002382266.1 1148528 R 585054 CDS YP_002382267.1 218548476 7119910 complement(1148903..1150006) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; AdoMet-dependent methyltransferase 1150006 yccW 7119910 yccW Escherichia fergusonii ATCC 35469 AdoMet-dependent methyltransferase YP_002382267.1 1148903 R 585054 CDS YP_002382268.1 218548477 7123611 1149975..1150466 1 NC_011740.1 catalyzes the hydrolysis of acylphosphate; acylphosphatase 1150466 yccX 7123611 yccX Escherichia fergusonii ATCC 35469 acylphosphatase YP_002382268.1 1149975 D 585054 CDS YP_002382269.1 218548478 7119911 complement(1150463..1150792) 1 NC_011740.1 transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein TusE 1150792 tusE 7119911 tusE Escherichia fergusonii ATCC 35469 sulfur transfer protein TusE YP_002382269.1 1150463 R 585054 CDS YP_002382270.1 218548479 7122610 complement(1150883..1151542) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 6376117; Product type m : membrane component; hypothetical protein 1151542 yccA 7122610 yccA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382270.1 1150883 R 585054 CDS YP_002382271.1 218548480 7120028 1152124..1152885 1 NC_011740.1 hypothetical protein 1152885 7120028 EFER_1108 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382271.1 1152124 D 585054 CDS YP_002382272.1 218548481 7120261 complement(1153042..1153176) 1 NC_011740.1 hypothetical protein 1153176 7120261 EFER_1109 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382272.1 1153042 R 585054 CDS YP_002382273.1 218548482 7120262 1153195..1154313 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86192450, 90202716, 92215587; Product type e : enzyme; hydrogenase 1 small subunit 1154313 hyaA 7120262 hyaA Escherichia fergusonii ATCC 35469 hydrogenase 1 small subunit YP_002382273.1 1153195 D 585054 CDS YP_002382274.1 218548483 7122235 1154310..1156103 1 NC_011740.1 involved in hydrogen cycling during fermentative growth; hydrogenase 1 large subunit 1156103 hyaB 7122235 hyaB Escherichia fergusonii ATCC 35469 hydrogenase 1 large subunit YP_002382274.1 1154310 D 585054 CDS YP_002382275.1 218548484 7122236 1156122..1156829 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90202716, 91310595, 92215587; Product type c : carrier; hydrogenase 1 b-type cytochrome subunit 1156829 hyaC 7122236 hyaC Escherichia fergusonii ATCC 35469 hydrogenase 1 b-type cytochrome subunit YP_002382275.1 1156122 D 585054 CDS YP_002382276.1 218548485 7124005 1156826..1157413 1 NC_011740.1 HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1); hydrogenase 1 maturation protease 1157413 hyaD 7124005 hyaD Escherichia fergusonii ATCC 35469 hydrogenase 1 maturation protease YP_002382276.1 1156826 D 585054 CDS YP_002382277.1 218548486 7122237 1157410..1157808 1 NC_011740.1 involved in processing hydrogenase proteins HyaA and HyaB; hydrogenase-1 operon protein HyaE 1157808 hyaE 7122237 hyaE Escherichia fergusonii ATCC 35469 hydrogenase-1 operon protein HyaE YP_002382277.1 1157410 D 585054 CDS YP_002382278.1 218548487 7122238 1157745..1158659 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90202716, 91310595, 92215587; Product type f : factor; hydrogenase-1 nickel incorporation protein 1158659 hyaF 7122238 hyaF Escherichia fergusonii ATCC 35469 hydrogenase-1 nickel incorporation protein YP_002382278.1 1157745 D 585054 CDS YP_002382279.1 218548488 7122239 1158753..1159418 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1159418 yecA 7122239 yecA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382279.1 1158753 D 585054 CDS YP_002382280.1 218548489 7123883 complement(1159458..1160696) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89008121, 2022620; Product type t : transporter; tyrosine transporter 1160696 tyrP 7123883 tyrP Escherichia fergusonii ATCC 35469 tyrosine transporter YP_002382280.1 1159458 R 585054 CDS YP_002382281.1 218548490 7122613 1160828..1161103 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1161103 yecH 7122613 yecH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382281.1 1160828 D 585054 CDS YP_002382282.1 218548491 7121531 complement(1161141..1161638) 1 NC_011740.1 cytoplasmic iron storage protein; ferritin 1161638 ftn 7121531 ftn Escherichia fergusonii ATCC 35469 ferritin YP_002382282.1 1161141 R 585054 CDS YP_002382283.1 218548492 7120143 complement(1161768..1162103) 1 NC_011740.1 hypothetical protein 1162103 7120143 EFER_1120 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382283.1 1161768 R 585054 CDS YP_002382284.1 218548493 7123130 complement(1162249..1162752) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; ferritin-like protein 1162752 yecI 7123130 yecI Escherichia fergusonii ATCC 35469 ferritin-like protein YP_002382284.1 1162249 R 585054 CDS YP_002382285.1 218548494 7121532 1163710..1164699 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89255061, 90375534, 2445996, 326784, 326785, 6885805, 7031057, 9298646; Product type t : transporter; L-arabinose ABC transporter periplasmic-binding protein 1164699 araF 7121532 araF Escherichia fergusonii ATCC 35469 L-arabinose ABC transporter periplasmic-binding protein YP_002382285.1 1163710 D 585054 CDS YP_002382286.1 218548495 7120530 1164794..1166308 1 NC_011740.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter ATP-binding protein 1166308 araG 7120530 araG Escherichia fergusonii ATCC 35469 L-arabinose transporter ATP-binding protein YP_002382286.1 1164794 D 585054 CDS YP_002382287.1 218548496 7120531 1166323..1167309 1 NC_011740.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter permease 1167309 araH 7120531 araH Escherichia fergusonii ATCC 35469 L-arabinose transporter permease YP_002382287.1 1166323 D 585054 CDS YP_002382288.1 218548497 7120532 1167463..1168266 1 NC_011740.1 biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature; trehalose-6-phosphate phosphatase 1168266 otsB 7120532 otsB Escherichia fergusonii ATCC 35469 trehalose-6-phosphate phosphatase YP_002382288.1 1167463 D 585054 CDS YP_002382289.1 218548498 7119705 1168241..1169665 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92078100, 92121128, 93302496, 8045430; Product type e : enzyme; trehalose-6-phosphate synthase 1169665 otsA 7119705 otsA Escherichia fergusonii ATCC 35469 trehalose-6-phosphate synthase YP_002382289.1 1168241 D 585054 CDS YP_002382290.1 218548499 7119704 complement(1169672..1170100) 1 NC_011740.1 ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspC 1170100 yecG 7119704 yecG Escherichia fergusonii ATCC 35469 universal stress protein UspC YP_002382290.1 1169672 R 585054 CDS YP_002382291.1 218548500 7121530 1170810..1171268 1 NC_011740.1 with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems; transcriptional activator FlhD 1171268 flhD 7121530 flhD Escherichia fergusonii ATCC 35469 transcriptional activator FlhD YP_002382291.1 1170810 D 585054 CDS YP_002382292.1 218548501 7122981 1171271..1171849 1 NC_011740.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems; transcriptional activator FlhC 1171849 flhC 7122981 flhC Escherichia fergusonii ATCC 35469 transcriptional activator FlhC YP_002382292.1 1171271 D 585054 CDS YP_002382293.1 218548502 7122980 1171973..1172860 1 NC_011740.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 1172860 motA 7122980 motA Escherichia fergusonii ATCC 35469 flagellar motor protein MotA YP_002382293.1 1171973 D 585054 CDS YP_002382294.1 218548503 7120957 1172857..1173771 1 NC_011740.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB 1173771 motB 7120957 motB Escherichia fergusonii ATCC 35469 flagellar motor protein MotB YP_002382294.1 1172857 D 585054 CDS YP_002382295.1 218548504 7123782 1173716..1175731 1 NC_011740.1 chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component; chemotaxis protein CheA 1175731 cheA 7123782 cheA Escherichia fergusonii ATCC 35469 chemotaxis protein CheA YP_002382295.1 1173716 D 585054 CDS YP_002382296.1 218548505 7120886 1175748..1176242 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91126073, 91296802, 91317710, 2002011, 3510184; Product type r : regulator; purine-binding chemotaxis protein 1176242 cheW 7120886 cheW Escherichia fergusonii ATCC 35469 purine-binding chemotaxis protein YP_002382296.1 1175748 D 585054 CDS YP_002382297.1 218548506 7120888 1176461..1177081 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; Type I pilus protein CsuA/B 1177081 7120888 EFER_1135 Escherichia fergusonii ATCC 35469 Type I pilus protein CsuA/B YP_002382297.1 1176461 D 585054 CDS YP_002382298.1 218548507 7123670 1177094..1177633 1 NC_011740.1 hypothetical protein 1177633 7123670 EFER_1136 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382298.1 1177094 D 585054 CDS YP_002382299.1 218548508 7120263 1177646..1178392 1 NC_011740.1 hypothetical protein 1178392 7120263 EFER_1137 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382299.1 1177646 D 585054 CDS YP_002382300.1 218548509 7120264 1178368..1180755 1 NC_011740.1 hypothetical protein 1180755 7120264 EFER_1138 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382300.1 1178368 D 585054 CDS YP_002382301.1 218548510 7120265 complement(1180652..1180954) 1 NC_011740.1 hypothetical protein 1180954 7120265 EFER_1139 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382301.1 1180652 R 585054 CDS YP_002382302.1 218548511 7120266 1180737..1181711 1 NC_011740.1 hypothetical protein 1181711 7120266 EFER_1140 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382302.1 1180737 D 585054 CDS YP_002382303.1 218548512 7120267 1181771..1183336 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90094243, 92165727, 6305515, 9315712; Product type r : regulator; methyl-accepting chemotaxis protein II 1183336 tar 7120267 tar Escherichia fergusonii ATCC 35469 methyl-accepting chemotaxis protein II YP_002382303.1 1181771 D 585054 CDS YP_002382304.1 218548513 7123956 1183356..1184222 1 NC_011740.1 methylates the MCP; chemotaxis methyltransferase CheR 1184222 cheR 7123956 cheR Escherichia fergusonii ATCC 35469 chemotaxis methyltransferase CheR YP_002382304.1 1183356 D 585054 CDS YP_002382305.1 218548514 7120887 1184219..1185268 1 NC_011740.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase 1185268 cheB 7120887 cheB Escherichia fergusonii ATCC 35469 chemotaxis-specific methylesterase YP_002382305.1 1184219 D 585054 CDS YP_002382306.1 218548515 7123235 1185283..1185672 1 NC_011740.1 chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble; chemotaxis regulatory protein CheY 1185672 cheY 7123235 cheY Escherichia fergusonii ATCC 35469 chemotaxis regulatory protein CheY YP_002382306.1 1185283 D 585054 CDS YP_002382307.1 218548516 7120889 1185680..1186324 1 NC_011740.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation; chemotaxis regulator CheZ 1186324 cheZ 7120889 cheZ Escherichia fergusonii ATCC 35469 chemotaxis regulator CheZ YP_002382307.1 1185680 D 585054 CDS YP_002382308.1 218548517 7120890 complement(1186370..1186690) 1 NC_011740.1 with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA; chaperone-modulator protein CbpM 1186690 cbpM 7120890 cbpM Escherichia fergusonii ATCC 35469 chaperone-modulator protein CbpM YP_002382308.1 1186370 R 585054 CDS YP_002382309.1 218548518 7123766 complement(1186675..1187595) 1 NC_011740.1 functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock; curved DNA-binding protein CbpA 1187595 cbpA 7123766 cbpA Escherichia fergusonii ATCC 35469 curved DNA-binding protein CbpA YP_002382309.1 1186675 R 585054 CDS YP_002382310.1 218548519 7120862 complement(1187798..1188169) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1188169 7120862 EFER_1148 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382310.1 1187798 R 585054 CDS YP_002382311.1 218548520 7120268 complement(1188151..1189404) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; D-amino acid dehydrogenase 1189404 dadA 7120268 dadA Escherichia fergusonii ATCC 35469 D-amino acid dehydrogenase YP_002382311.1 1188151 R 585054 CDS YP_002382312.1 218548521 7124115 complement(1189455..1190369) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; LysR family transcriptional regulator 1190369 7124115 EFER_1150 Escherichia fergusonii ATCC 35469 LysR family transcriptional regulator YP_002382312.1 1189455 R 585054 CDS YP_002382313.1 218548522 7123140 1190609..1192075 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 1192075 7123140 EFER_1151 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382313.1 1190609 D 585054 CDS YP_002382314.1 218548523 7120329 complement(1192067..1192396) 1 NC_011740.1 hypothetical protein 1192396 7120329 EFER_1152 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382314.1 1192067 R 585054 CDS YP_002382315.1 218548524 7120330 1192225..1193466 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12455612, 90368616, 91297199, 2153660, 9298646; Product type e : enzyme; glucose-1-phosphatase/inositol phosphatase 1193466 agp 7120330 agp Escherichia fergusonii ATCC 35469 glucose-1-phosphatase/inositol phosphatase YP_002382315.1 1192225 D 585054 CDS YP_002382316.1 218548525 7122288 complement(1193560..1193787) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1193787 yccJ 7122288 yccJ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382316.1 1193560 R 585054 CDS YP_002382317.1 218548526 7119907 complement(1193808..1194404) 1 NC_011740.1 stationary phase protein that binds TrpR repressor; TrpR binding protein WrbA 1194404 wrbA 7119907 wrbA Escherichia fergusonii ATCC 35469 TrpR binding protein WrbA YP_002382317.1 1193808 R 585054 CDS YP_002382318.1 218548527 7123683 1194797..1194949 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 1194949 7123683 EFER_1157 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382318.1 1194797 D 585054 CDS YP_002382319.1 218548528 7120331 1195157..1195795 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542; Product type r : regulator; alternative pyrimidine degradation pathway DNA-binding transcriptional regulator 1195795 rutR 7120331 rutR Escherichia fergusonii ATCC 35469 alternative pyrimidine degradation pathway DNA-binding transcriptional regulator YP_002382319.1 1195157 D 585054 CDS YP_002382320.1 218548529 7121168 1196881..1199229 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1199229 yliE 7121168 yliE Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382320.1 1196881 D 585054 CDS YP_002382321.1 218548530 7123415 1199063..1200574 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 17208514; Product type pe : enzyme; hypothetical protein 1200574 yliF 7123415 yliF Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382321.1 1199063 D 585054 CDS YP_002382322.1 218548531 7122049 1200643..1202748 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11260463, 11929533; Product type e : enzyme; cellulose synthase catalytic subunit 1202748 bcsA 7122049 bcsA Escherichia fergusonii ATCC 35469 cellulose synthase catalytic subunit YP_002382322.1 1200643 D 585054 CDS YP_002382323.1 218548532 7123357 1202813..1204960 1 NC_011740.1 binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); cellulose synthase regulator protein 1204960 bcsB 7123357 bcsB Escherichia fergusonii ATCC 35469 cellulose synthase regulator protein YP_002382323.1 1202813 D 585054 CDS YP_002382324.1 218548533 7121650 complement(1204998..1205231) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1205231 yedF 7121650 yedF Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382324.1 1204998 R 585054 CDS YP_002382325.1 218548534 7121539 complement(1205228..1206433) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; inner membrane protein 1206433 yedE 7121539 yedE Escherichia fergusonii ATCC 35469 inner membrane protein YP_002382325.1 1205228 R 585054 CDS YP_002382326.1 218548535 7121538 1206620..1207033 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1207033 yedD 7121538 yedD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382326.1 1206620 D 585054 CDS YP_002382327.1 218548536 7121537 complement(1207066..1208553) 1 NC_011740.1 converts 1,4-alpha-D-glucans to maltodextrin; alpha-amylase 1208553 amyA 7121537 amyA Escherichia fergusonii ATCC 35469 alpha-amylase YP_002382327.1 1207066 R 585054 CDS YP_002382328.1 218548537 7120516 complement(1208619..1208990) 1 NC_011740.1 binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family; flagellar biosynthesis protein FliT 1208990 fliT 7120516 fliT Escherichia fergusonii ATCC 35469 flagellar biosynthesis protein FliT YP_002382328.1 1208619 R 585054 CDS YP_002382329.1 218548538 7122996 complement(1208987..1209397) 1 NC_011740.1 flagellin specific chaperone; flagellar protein FliS 1209397 fliS 7122996 fliS Escherichia fergusonii ATCC 35469 flagellar protein FliS YP_002382329.1 1208987 R 585054 CDS YP_002382330.1 218548539 7122995 complement(1209416..1210822) 1 NC_011740.1 involved in flagellin assembly; flagellar capping protein 1210822 fliD 7122995 fliD Escherichia fergusonii ATCC 35469 flagellar capping protein YP_002382330.1 1209416 R 585054 CDS YP_002382331.1 218548540 7122983 1211032..1212564 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7690024; Product type s : structure; Flagellin 1212564 fliC 7122983 fliC Escherichia fergusonii ATCC 35469 Flagellin YP_002382331.1 1211032 D 585054 CDS YP_002382332.1 218548541 7122982 1212730..1213446 1 NC_011740.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor 1213446 fliA 7122982 fliA Escherichia fergusonii ATCC 35469 flagellar biosynthesis sigma factor YP_002382332.1 1212730 D 585054 CDS YP_002382333.1 218548542 7123564 1213505..1214044 1 NC_011740.1 expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence; flagella biosynthesis protein FliZ 1214044 fliZ 7123564 fliZ Escherichia fergusonii ATCC 35469 flagella biosynthesis protein FliZ YP_002382333.1 1213505 D 585054 CDS YP_002382334.1 218548543 7123567 1214132..1214932 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96125225, 8450713, 8774726, 9298646, 9740056; Product type t : transporter; cystine transporter subunit 1214932 fliY 7123567 fliY Escherichia fergusonii ATCC 35469 cystine transporter subunit YP_002382334.1 1214132 D 585054 CDS YP_002382335.1 218548544 7124140 1215039..1216025 1 NC_011740.1 catalyzes the formation of pyruvate from D-cysteine; D-cysteine desulfhydrase 1216025 yedO 7124140 yedO Escherichia fergusonii ATCC 35469 D-cysteine desulfhydrase YP_002382335.1 1215039 D 585054 CDS YP_002382336.1 218548545 7121542 1216041..1216709 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter permease 1216709 yecS 7121542 yecS Escherichia fergusonii ATCC 35469 ABC transporter permease YP_002382336.1 1216041 D 585054 CDS YP_002382337.1 218548546 7123884 1216706..1217458 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; amino-acid ABC transporter ATP-binding protein YecC 1217458 yecC 7123884 yecC Escherichia fergusonii ATCC 35469 amino-acid ABC transporter ATP-binding protein YecC YP_002382337.1 1216706 D 585054 CDS YP_002382338.1 218548547 7121527 1217653..1218408 1 NC_011740.1 regulates genes involved in cell division; DNA-binding transcriptional activator SdiA 1218408 sdiA 7121527 sdiA Escherichia fergusonii ATCC 35469 DNA-binding transcriptional activator SdiA YP_002382338.1 1217653 D 585054 CDS YP_002382339.1 218548548 7121759 complement(1218476..1218700) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3515318, 7567469; hypothetical protein 1218700 yecF 7121759 yecF Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382339.1 1218476 R 585054 CDS YP_002382340.1 218548549 7123336 1219146..1219802 1 NC_011740.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; response regulator 1219802 uvrY 7123336 uvrY Escherichia fergusonii ATCC 35469 response regulator YP_002382340.1 1219146 D 585054 CDS YP_002382341.1 218548550 7122649 1219799..1221631 1 NC_011740.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 1221631 uvrC 7122649 uvrC Escherichia fergusonii ATCC 35469 excinuclease ABC subunit C YP_002382341.1 1219799 D 585054 CDS YP_002382342.1 218548551 7122647 1221688..1222236 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 381294, 7007311, 94253011, 1323047, 3003065, 8917447; Product type e : enzyme; phosphatidylglycerophosphate synthetase 1222236 pgsA 7122647 pgsA Escherichia fergusonii ATCC 35469 phosphatidylglycerophosphate synthetase YP_002382342.1 1221688 D 585054 CDS YP_002382343.1 218548552 7123631 complement(1222838..1224100) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12912904; Product type t : transporter; voltage-gated potassium channel 1224100 kch 7123631 kch Escherichia fergusonii ATCC 35469 voltage-gated potassium channel YP_002382343.1 1222838 R 585054 CDS YP_002382344.1 218548553 7120802 1224433..1225977 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92049231, 96198179; Product type c : carrier; cytochrome bd-II oxidase subunit I 1225977 appC 7120802 appC Escherichia fergusonii ATCC 35469 cytochrome bd-II oxidase subunit I YP_002382344.1 1224433 D 585054 CDS YP_002382345.1 218548554 7120524 1225989..1227125 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92049231, 96198179; Product type c : carrier; cytochrome bd-II oxidase subunit II 1227125 appB 7120524 appB Escherichia fergusonii ATCC 35469 cytochrome bd-II oxidase subunit II YP_002382345.1 1225989 D 585054 CDS YP_002382346.1 218548555 7120523 complement(1227396..1227776) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; lipoprotein 1227776 7120523 EFER_1187 Escherichia fergusonii ATCC 35469 lipoprotein YP_002382346.1 1227396 R 585054 CDS YP_002382347.1 218548556 7120332 complement(1227894..1230638) 1 NC_011740.1 Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide; hybrid sensory histidine kinase TorS 1230638 torS 7120332 torS Escherichia fergusonii ATCC 35469 hybrid sensory histidine kinase TorS YP_002382347.1 1227894 R 585054 CDS YP_002382348.1 218548557 7122148 1230715..1231743 1 NC_011740.1 periplasmic sensory protein associated with the TorRS two-component regulatory system; TMAO reductase system periplasmic protein TorT 1231743 torT 7122148 torT Escherichia fergusonii ATCC 35469 TMAO reductase system periplasmic protein TorT YP_002382348.1 1230715 D 585054 CDS YP_002382349.1 218548558 7123987 complement(1231716..1232408) 1 NC_011740.1 response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes; DNA-binding transcriptional regulator TorR 1232408 torR 7123987 torR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator TorR YP_002382349.1 1231716 R 585054 CDS YP_002382350.1 218548559 7122147 1232538..1233710 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94293785, 94314186, 99340208, 11056172, 11562502; Product type c : carrier; trimethylamine N-oxide (TMAO) reductase I, cytochrome c-type subunit 1233710 torC 7122147 torC Escherichia fergusonii ATCC 35469 trimethylamine N-oxide (TMAO) reductase I, cytochrome c-type subunit YP_002382350.1 1232538 D 585054 CDS YP_002382351.1 218548560 7122145 1233710..1236256 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88193091, 90089471, 94293785, 8302830, 8022286; Product type e : enzyme; trimethylamine N-oxide (TMAO) reductase I, catalytic subunit 1236256 torA 7122145 torA Escherichia fergusonii ATCC 35469 trimethylamine N-oxide (TMAO) reductase I, catalytic subunit YP_002382351.1 1233710 D 585054 CDS YP_002382352.1 218548561 7122144 1236220..1236849 1 NC_011740.1 TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; chaperone protein TorD 1236849 torD 7122144 torD Escherichia fergusonii ATCC 35469 chaperone protein TorD YP_002382352.1 1236220 D 585054 CDS YP_002382353.1 218548562 7122146 1236998..1238146 1 NC_011740.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 1238146 flhB 7122146 flhB Escherichia fergusonii ATCC 35469 flagellar biosynthesis protein FlhB YP_002382353.1 1236998 D 585054 CDS YP_002382354.1 218548563 7122979 1238139..1240217 1 NC_011740.1 membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 1240217 flhA 7122979 flhA Escherichia fergusonii ATCC 35469 flagellar biosynthesis protein FlhA YP_002382354.1 1238139 D 585054 CDS YP_002382355.1 218548564 7122978 1240217..1240612 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8002587, 1482109, 89181349; hypothetical protein 1240612 flhE 7122978 flhE Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382355.1 1240217 D 585054 CDS YP_002382356.1 218548565 7124138 complement(1240810..1242543) 1 NC_011740.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 1242543 argS 7124138 argS Escherichia fergusonii ATCC 35469 arginyl-tRNA synthetase YP_002382356.1 1240810 R 585054 CDS YP_002382357.1 218548566 7123179 1242781..1243347 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12660999; Product type pe : enzyme; hypothetical protein 1243347 yecM 7123179 yecM Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382357.1 1242781 D 585054 CDS YP_002382358.1 218548567 7121533 1243353..1244105 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95362641, 7635807; Product type t : transporter; copper homeostasis protein CutC 1244105 cutC 7121533 cutC Escherichia fergusonii ATCC 35469 copper homeostasis protein CutC YP_002382358.1 1243353 D 585054 CDS YP_002382359.1 218548568 7122833 complement(1244186..1245157) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1245157 yecP 7122833 yecP Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382359.1 1244186 R 585054 CDS YP_002382360.1 218548569 7123337 complement(1245154..1245897) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11746687; Product type e : enzyme; AdoMet-dependent methyltransferase 1245897 yecO 7123337 yecO Escherichia fergusonii ATCC 35469 AdoMet-dependent methyltransferase YP_002382360.1 1245154 R 585054 CDS YP_002382361.1 218548570 7121535 complement(1245938..1246333) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1246333 yecN 7121535 yecN Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382361.1 1245938 R 585054 CDS YP_002382362.1 218548571 7121534 complement(1246386..1247204) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2129559, 7984428; hypothetical protein 1247204 yecE 7121534 yecE Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382362.1 1246386 R 585054 CDS YP_002382363.1 218548572 7121529 complement(1247201..1247767) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 1247767 yecD 7121529 yecD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382363.1 1247201 R 585054 CDS YP_002382364.1 218548573 7121528 1248077..1249849 1 NC_011740.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1249849 aspS 7121528 aspS Escherichia fergusonii ATCC 35469 aspartyl-tRNA synthetase YP_002382364.1 1248077 D 585054 CDS YP_002382365.1 218548574 7123183 1249851..1250294 1 NC_011740.1 converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase 1250294 ntpA 7123183 ntpA Escherichia fergusonii ATCC 35469 dATP pyrophosphohydrolase YP_002382365.1 1249851 D 585054 CDS YP_002382366.1 218548575 7119667 1250323..1251063 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1251063 yebC 7119667 yebC Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382366.1 1250323 D 585054 CDS YP_002382367.1 218548576 7121515 1251097..1251618 1 NC_011740.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 1251618 ruvC 7121515 ruvC Escherichia fergusonii ATCC 35469 Holliday junction resolvase YP_002382367.1 1251097 D 585054 CDS YP_002382368.1 218548577 7121170 complement(1251620..1252222) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1252222 yebB 7121170 yebB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382368.1 1251620 R 585054 CDS YP_002382369.1 218548578 7123333 1252497..1253108 1 NC_011740.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 1253108 ruvA 7123333 ruvA Escherichia fergusonii ATCC 35469 Holliday junction DNA helicase RuvA YP_002382369.1 1252497 D 585054 CDS YP_002382370.1 218548579 7123278 1253117..1254127 1 NC_011740.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1254127 ruvB 7123278 ruvB Escherichia fergusonii ATCC 35469 Holliday junction DNA helicase RuvB YP_002382370.1 1253117 D 585054 CDS YP_002382371.1 218548580 7121169 complement(1254273..1255058) 1 NC_011740.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter membrane protein 1255058 znuB 7121169 znuB Escherichia fergusonii ATCC 35469 high-affinity zinc transporter membrane protein YP_002382371.1 1254273 R 585054 CDS YP_002382372.1 218548581 7119776 complement(1255051..1255809) 1 NC_011740.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter ATPase 1255809 znuC 7119776 znuC Escherichia fergusonii ATCC 35469 high-affinity zinc transporter ATPase YP_002382372.1 1255051 R 585054 CDS YP_002382373.1 218548582 7122666 1255834..1256820 1 NC_011740.1 involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic protein 1256820 znuA 7122666 znuA Escherichia fergusonii ATCC 35469 high-affinity zinc transporter periplasmic protein YP_002382373.1 1255834 D 585054 CDS YP_002382374.1 218548583 7119775 1256836..1258158 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1732206; Product type pe : enzyme; hypothetical protein 1258158 yebA 7119775 yebA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382374.1 1256836 D 585054 CDS YP_002382375.1 218548584 7121514 1258279..1259250 1 NC_011740.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 1259250 lpxM 7121514 lpxM Escherichia fergusonii ATCC 35469 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase YP_002382375.1 1258279 D 585054 CDS YP_002382376.1 218548585 7121204 complement(1259402..1260844) 1 NC_011740.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1260844 pykA 7121204 pykA Escherichia fergusonii ATCC 35469 pyruvate kinase YP_002382376.1 1259402 R 585054 CDS YP_002382377.1 218548586 7122332 complement(1260966..1261835) 1 NC_011740.1 Represses the expression of the zwf, eda, glp and gap; DNA-binding transcriptional regulator HexR 1261835 yebK 7122332 yebK Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator HexR YP_002382377.1 1260966 R 585054 CDS YP_002382378.1 218548587 7121519 1262165..1263640 1 NC_011740.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1263640 zwf 7121519 zwf Escherichia fergusonii ATCC 35469 glucose-6-phosphate 1-dehydrogenase YP_002382378.1 1262165 D 585054 CDS YP_002382379.1 218548588 7122061 1263863..1265674 1 NC_011740.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase 1265674 edd 7122061 edd Escherichia fergusonii ATCC 35469 phosphogluconate dehydratase YP_002382379.1 1263863 D 585054 CDS YP_002382380.1 218548589 7124131 1265711..1266352 1 NC_011740.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 1266352 eda 7124131 eda Escherichia fergusonii ATCC 35469 keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase YP_002382380.1 1265711 D 585054 CDS YP_002382381.1 218548590 7122937 complement(1266517..1267695) 1 NC_011740.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 1267695 purT 7122937 purT Escherichia fergusonii ATCC 35469 phosphoribosylglycinamide formyltransferase 2 YP_002382381.1 1266517 R 585054 CDS YP_002382382.1 218548591 7122328 1267679..1268116 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type ph : phenotype; DNA damage-inducible protein 1268116 yebG 7122328 yebG Escherichia fergusonii ATCC 35469 DNA damage-inducible protein YP_002382382.1 1267679 D 585054 CDS YP_002382383.1 218548592 7121518 1268171..1268539 1 NC_011740.1 secreted protein; unknown function; hypothetical protein 1268539 yebF 7121518 yebF Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382383.1 1268171 D 585054 CDS YP_002382384.1 218548593 7121517 1268750..1269415 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1269415 yebE 7121517 yebE Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382384.1 1268750 D 585054 CDS YP_002382385.1 218548594 7121516 1269504..1271579 1 NC_011740.1 PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues; protease 2 1271579 ptrB 7121516 ptrB Escherichia fergusonii ATCC 35469 protease 2 YP_002382385.1 1269504 D 585054 CDS YP_002382386.1 218548595 7122313 complement(1271561..1272223) 1 NC_011740.1 3'-5' exonuclease activity on single or double-strand DNA; exodeoxyribonuclease X 1272223 exoX 7122313 exoX Escherichia fergusonii ATCC 35469 exodeoxyribonuclease X YP_002382386.1 1271561 R 585054 CDS YP_002382387.1 218548596 7119976 complement(1272247..1272936) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1272936 7119976 EFER_1230 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382387.1 1272247 R 585054 CDS YP_002382388.1 218548597 7120333 complement(1273011..1273328) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; DNA polymerase III subunit theta 1273328 7120333 EFER_1231 Escherichia fergusonii ATCC 35469 DNA polymerase III subunit theta YP_002382388.1 1273011 R 585054 CDS YP_002382389.1 218548598 7120334 1273380..1273754 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1273754 7120334 EFER_1232 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382389.1 1273380 D 585054 CDS YP_002382390.1 218548599 7120335 1273757..1274629 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; copper ion transport inner membrane protein YebZ 1274629 yebZ 7120335 yebZ Escherichia fergusonii ATCC 35469 copper ion transport inner membrane protein YebZ YP_002382390.1 1273757 D 585054 CDS YP_002382391.1 218548600 7121526 1274641..1274982 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1274982 yebY 7121526 yebY Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382391.1 1274641 D 585054 CDS YP_002382392.1 218548601 7123335 1275000..1275152 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 1275152 7123335 EFER_1235 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382392.1 1275000 D 585054 CDS YP_002382393.1 218548602 7123819 1275377..1276033 1 NC_011740.1 Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins; serine/threonine protein phosphatase 1 1276033 pphA 7123819 pphA Escherichia fergusonii ATCC 35469 serine/threonine protein phosphatase 1 YP_002382393.1 1275377 D 585054 CDS YP_002382394.1 218548603 7120111 complement(1276034..1276309) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1276309 yebW 7120111 yebW Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382394.1 1276034 R 585054 CDS YP_002382395.1 218548604 7123882 complement(1276330..1276566) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1276566 yebV 7123882 yebV Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382395.1 1276330 R 585054 CDS YP_002382396.1 218548605 7121525 complement(1276685..1278124) 1 NC_011740.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA; rRNA (cytosine-C(5)-)-methyltransferase RsmF 1278124 yebU 7121525 yebU Escherichia fergusonii ATCC 35469 rRNA (cytosine-C(5)-)-methyltransferase RsmF YP_002382396.1 1276685 R 585054 CDS YP_002382397.1 218548606 7121524 complement(1278204..1280837) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1280837 yebT 7121524 yebT Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382397.1 1278204 R 585054 CDS YP_002382398.1 218548607 7121523 complement(1280806..1282089) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1282089 yebS 7121523 yebS Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382398.1 1280806 R 585054 CDS YP_002382399.1 218548608 7121522 1282165..1282716 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1282716 yebR 7121522 yebR Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382399.1 1282165 D 585054 CDS YP_002382400.1 218548609 7123334 1282813..1283502 1 NC_011740.1 affects solute and DNA transport through an unknown mechanism; solute/DNA competence effector 1283502 proQ 7123334 proQ Escherichia fergusonii ATCC 35469 solute/DNA competence effector YP_002382400.1 1282813 D 585054 CDS YP_002382401.1 218548610 7123649 1283522..1285570 1 NC_011740.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease 1285570 prc 7123649 prc Escherichia fergusonii ATCC 35469 carboxy-terminal protease YP_002382401.1 1283522 D 585054 CDS YP_002382402.1 218548611 7120122 1285751..1286632 1 NC_011740.1 metalloprotease; heat shock protein HtpX 1286632 htpX 7120122 htpX Escherichia fergusonii ATCC 35469 heat shock protein HtpX YP_002382402.1 1285751 D 585054 CDS YP_002382403.1 218548612 7122232 complement(1286680..1288053) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; MFS superfamily transporter 1288053 yebQ 7122232 yebQ Escherichia fergusonii ATCC 35469 MFS superfamily transporter YP_002382403.1 1286680 R 585054 CDS YP_002382404.1 218548613 7121521 1288229..1289011 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15659677, 4359651; Product type r : regulator; DNA-binding transcriptional repressor KdgR 1289011 kdgR 7121521 kdgR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional repressor KdgR YP_002382404.1 1288229 D 585054 CDS YP_002382405.1 218548614 7120804 complement(1289345..1289464) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1289464 7120804 EFER_1248 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382405.1 1289345 R 585054 CDS YP_002382406.1 218548615 7120337 1289603..1289758 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1289758 yobG 7120337 yobG Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382406.1 1289603 D 585054 CDS YP_002382407.1 218548616 7121728 1289832..1290119 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1290119 7121728 EFER_1250 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382407.1 1289832 D 585054 CDS YP_002382408.1 218548617 7120338 1290945..1291088 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1291088 yobF 7120338 yobF Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382408.1 1290945 D 585054 CDS YP_002382409.1 218548618 7121727 1291101..1291310 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20345064, 21101802, 94293754, 12071744, 7984109, 8022261, 9298646, 9868784, 9921691; Product type f : factor; cold shock-like protein CspC 1291310 cspC 7121727 cspC Escherichia fergusonii ATCC 35469 cold shock-like protein CspC YP_002382409.1 1291101 D 585054 CDS YP_002382410.1 218548619 7122819 1291467..1292276 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9440525; Product type e : enzyme; Ribosomal RNA large subunit methyltransferase A (rRNA (guanine-N(1)-)-methyltransferase) (23S rRNA m1G745 methyltransferase) 1292276 rrmA 7122819 rrmA Escherichia fergusonii ATCC 35469 Ribosomal RNA large subunit methyltransferase A (rRNA (guanine-N(1)-)-methyltransferase) (23S rRNA m1G745 methyltransferase) YP_002382410.1 1291467 D 585054 CDS YP_002382411.1 218548620 7121142 complement(1292273..1292839) 1 NC_011740.1 membrane protein YebN; hypothetical protein 1292839 yebN 7121142 yebN Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382411.1 1292273 R 585054 CDS YP_002382412.1 218548621 7121520 complement(1292836..1293081) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1293081 7121520 EFER_1255 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382412.1 1292836 R 585054 CDS YP_002382413.1 218548622 7120339 complement(1293268..1293726) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1293726 yobD 7120339 yobD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382413.1 1293268 R 585054 CDS YP_002382414.1 218548623 7121726 complement(1293781..1294641) 1 NC_011740.1 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; PTS system mannose-specific transporter subunit IID 1294641 manZ 7121726 manZ Escherichia fergusonii ATCC 35469 PTS system mannose-specific transporter subunit IID YP_002382414.1 1293781 R 585054 CDS YP_002382415.1 218548624 7123832 complement(1294645..1295445) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10473571, 87165962, 90036983, 94086520, 97128775, 7811395, 8774730; Product type t : transporter; mannose-specific PTS system transporter subunit IIC 1295445 manY 7123832 manY Escherichia fergusonii ATCC 35469 mannose-specific PTS system transporter subunit IIC YP_002382415.1 1294645 R 585054 CDS YP_002382416.1 218548625 7123289 complement(1295507..1296478) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87165962, 90036983, 8131846, 8676384, 9074635, 9298646; Product type t : transporter; PTS system mannose-specific transporter subunit IIAB 1296478 manX 7123289 manX Escherichia fergusonii ATCC 35469 PTS system mannose-specific transporter subunit IIAB YP_002382416.1 1295507 R 585054 CDS YP_002382417.1 218548626 7121230 1296912..1298498 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; membrane protein 1298498 yoaE 7121230 yoaE Escherichia fergusonii ATCC 35469 membrane protein YP_002382417.1 1296912 D 585054 CDS YP_002382418.1 218548627 7121723 complement(1298501..1300108) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16513732; Product type pe : enzyme; cyclic di-GMP phosphodiesterase 1300108 adrB 7121723 adrB Escherichia fergusonii ATCC 35469 cyclic di-GMP phosphodiesterase YP_002382418.1 1298501 R 585054 CDS YP_002382419.1 218548628 7122278 complement(1300230..1301594) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15155761, 89359152, 91056090, 93170282; Product type e : enzyme; L-serine deaminase I 1301594 sdaA 7122278 sdaA Escherichia fergusonii ATCC 35469 L-serine deaminase I YP_002382419.1 1300230 R 585054 CDS YP_002382420.1 218548629 7123919 complement(1301778..1302356) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7567469; Product type pe : enzyme; hypothetical protein 1302356 yeaB 7123919 yeaB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382420.1 1301778 R 585054 CDS YP_002382421.1 218548630 7122728 complement(1302359..1303720) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88025006, 91067712, 91302313, 96011382, 6330050, 7896119; Product type e : enzyme; aminodeoxychorismate synthase subunit I 1303720 pabB 7122728 pabB Escherichia fergusonii ATCC 35469 aminodeoxychorismate synthase subunit I YP_002382421.1 1302359 R 585054 CDS YP_002382422.1 218548631 7122550 1303794..1303973 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1303973 yoaH 7122550 yoaH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382422.1 1303794 D 585054 CDS YP_002382423.1 218548632 7121725 1304144..1304389 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 1304389 7121725 EFER_1266 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382423.1 1304144 D 585054 CDS YP_002382424.1 218548633 7120340 1304471..1305370 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 1305370 7120340 EFER_1267 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382424.1 1304471 D 585054 CDS YP_002382425.1 218548634 7123141 complement(1305526..1305915) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1305915 yoaC 7123141 yoaC Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382425.1 1305526 R 585054 CDS YP_002382426.1 218548635 7123913 complement(1306087..1306431) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1306431 yoaB 7123913 yoaB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382426.1 1306087 R 585054 CDS YP_002382427.1 218548636 7121722 complement(1306684..1306896) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1306896 7121722 EFER_1270 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382427.1 1306684 R 585054 CDS YP_002382428.1 218548637 7120341 complement(1306893..1307105) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1307105 7120341 EFER_1271 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382428.1 1306893 R 585054 CDS YP_002382429.1 218548638 7123684 1307402..1309312 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; ATP-dependent helicase 1309312 yoaA 7123684 yoaA Escherichia fergusonii ATCC 35469 ATP-dependent helicase YP_002382429.1 1307402 D 585054 CDS YP_002382430.1 218548639 7123367 1309370..1310065 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; peptidase 1310065 yeaZ 7123367 yeaZ Escherichia fergusonii ATCC 35469 peptidase YP_002382430.1 1309370 D 585054 CDS YP_002382431.1 218548640 7121513 1310104..1310685 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16079137; Product type lp : lipoprotein; outer membrane-associated lipoprotein 1310685 yeaY 7121513 yeaY Escherichia fergusonii ATCC 35469 outer membrane-associated lipoprotein YP_002382431.1 1310104 D 585054 CDS YP_002382432.1 218548641 7123332 1310890..1312575 1 NC_011740.1 Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 1312575 fadD 7123332 fadD Escherichia fergusonii ATCC 35469 long-chain-fatty-acid--CoA ligase YP_002382432.1 1310890 D 585054 CDS YP_002382433.1 218548642 7119987 1312643..1313770 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88289400, 89053950, 93015723, 8107670; Product type e : enzyme; ribonuclease D 1313770 rnd 7119987 rnd Escherichia fergusonii ATCC 35469 ribonuclease D YP_002382433.1 1312643 D 585054 CDS YP_002382434.1 218548643 7121424 complement(1313809..1314789) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1314789 ycfS 7121424 ycfS Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382434.1 1313809 R 585054 CDS YP_002382435.1 218548644 7123614 complement(1314930..1318376) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14602898, 90158497, 92107993, 8465200; Product type f : factor; transcription-repair coupling factor 1318376 mfd 7123614 mfd Escherichia fergusonii ATCC 35469 transcription-repair coupling factor YP_002382435.1 1314930 R 585054 CDS YP_002382436.1 218548645 7120927 complement(1318504..1319577) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1319577 ycfT 7120927 ycfT Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382436.1 1318504 R 585054 CDS YP_002382437.1 218548646 7119928 1319839..1321038 1 NC_011740.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolC 1321038 lolC 7119928 lolC Escherichia fergusonii ATCC 35469 outer membrane-specific lipoprotein transporter subunit LolC YP_002382437.1 1319839 D 585054 CDS YP_002382438.1 218548647 7120845 1321031..1321732 1 NC_011740.1 outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone; lipoprotein transporter ATP-binding subunit 1321732 lolD 7120845 lolD Escherichia fergusonii ATCC 35469 lipoprotein transporter ATP-binding subunit YP_002382438.1 1321031 D 585054 CDS YP_002382439.1 218548648 7120846 1321732..1322976 1 NC_011740.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE 1322976 lolE 7120846 lolE Escherichia fergusonii ATCC 35469 outer membrane-specific lipoprotein transporter subunit LolE YP_002382439.1 1321732 D 585054 CDS YP_002382440.1 218548649 7120847 1323005..1323916 1 NC_011740.1 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 1323916 ycfX 7120847 ycfX Escherichia fergusonii ATCC 35469 N-acetyl-D-glucosamine kinase YP_002382440.1 1323005 D 585054 CDS YP_002382441.1 218548650 7119929 1323932..1324753 1 NC_011740.1 Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 1324753 cobB 7119929 cobB Escherichia fergusonii ATCC 35469 NAD-dependent deacetylase YP_002382441.1 1323932 D 585054 CDS YP_002382442.1 218548651 7120911 complement(1324890..1325675) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1325675 ycfZ 7120911 ycfZ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382442.1 1324890 R 585054 CDS YP_002382443.1 218548652 7123615 complement(1325672..1326133) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1326133 ymfA 7123615 ymfA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382443.1 1325672 R 585054 CDS YP_002382444.1 218548653 7123418 complement(1326191..1327237) 1 NC_011740.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate; spermidine/putrescine ABC transporter substrate-binding protein 1327237 potD 7123418 potD Escherichia fergusonii ATCC 35469 spermidine/putrescine ABC transporter substrate-binding protein YP_002382444.1 1326191 R 585054 CDS YP_002382445.1 218548654 7120101 complement(1327234..1328028) 1 NC_011740.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein 1328028 potC 7120101 potC Escherichia fergusonii ATCC 35469 spermidine/putrescine ABC transporter membrane protein YP_002382445.1 1327234 R 585054 CDS YP_002382446.1 218548655 7123644 complement(1328025..1328852) 1 NC_011740.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein 1328852 potB 7123644 potB Escherichia fergusonii ATCC 35469 spermidine/putrescine ABC transporter membrane protein YP_002382446.1 1328025 R 585054 CDS YP_002382447.1 218548656 7120100 complement(1328866..1330002) 1 NC_011740.1 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase 1330002 potA 7120100 potA Escherichia fergusonii ATCC 35469 putrescine/spermidine ABC transporter ATPase YP_002382447.1 1328866 R 585054 CDS YP_002382448.1 218548657 7120099 1330251..1331477 1 NC_011740.1 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1331477 pepT 7120099 pepT Escherichia fergusonii ATCC 35469 peptidase T YP_002382448.1 1330251 D 585054 CDS YP_002382449.1 218548658 7122579 complement(1331528..1332472) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1332472 yeaD 7122579 yeaD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382449.1 1331528 R 585054 CDS YP_002382450.1 218548659 7123525 complement(1332487..1333482) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 775311, 94131963, 98361923, 1862091, 2124629, 2990926, 7896119, 8636984, 9298646; Product type e : enzyme; glyceraldehyde-3-phosphate dehydrogenase 1333482 gapA 7123525 gapA Escherichia fergusonii ATCC 35469 glyceraldehyde-3-phosphate dehydrogenase YP_002382450.1 1332487 R 585054 CDS YP_002382451.1 218548660 7120173 1333825..1334238 1 NC_011740.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 1334238 msrB 7120173 msrB Escherichia fergusonii ATCC 35469 methionine sulfoxide reductase B YP_002382451.1 1333825 D 585054 CDS YP_002382452.1 218548661 7120974 1334235..1334558 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1334558 yeaC 7120974 yeaC Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382452.1 1334235 D 585054 CDS YP_002382453.1 218548662 7124094 complement(1334620..1335297) 1 NC_011740.1 catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide; nicotinamidase/pyrazinamidase 1335297 pncA 7124094 pncA Escherichia fergusonii ATCC 35469 nicotinamidase/pyrazinamidase YP_002382453.1 1334620 R 585054 CDS YP_002382454.1 218548663 7123102 complement(1335272..1336288) 1 NC_011740.1 converts asparagine to aspartate and ammonia; asparaginase 1336288 ansA 7123102 ansA Escherichia fergusonii ATCC 35469 asparaginase YP_002382454.1 1335272 R 585054 CDS YP_002382455.1 218548664 7120518 complement(1336404..1337114) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1337114 7120518 EFER_1298 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382455.1 1336404 R 585054 CDS YP_002382456.1 218548665 7123685 complement(1337250..1339385) 1 NC_011740.1 SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane; protease 4 1339385 sppA 7123685 sppA Escherichia fergusonii ATCC 35469 protease 4 YP_002382456.1 1337250 R 585054 CDS YP_002382457.1 218548666 7123380 1339267..1339818 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 1339818 ydjA 7123380 ydjA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382457.1 1339267 D 585054 CDS YP_002382458.1 218548667 7122722 1339935..1340978 1 NC_011740.1 catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase 1340978 selD 7122722 selD Escherichia fergusonii ATCC 35469 selenophosphate synthetase YP_002382458.1 1339935 D 585054 CDS YP_002382459.1 218548668 7123374 1340956..1342938 1 NC_011740.1 decatenates replicating daughter chromosomes; DNA topoisomerase III 1342938 topB 7123374 topB Escherichia fergusonii ATCC 35469 DNA topoisomerase III YP_002382459.1 1340956 D 585054 CDS YP_002382460.1 218548669 7122143 1343066..1344106 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1344106 ynjI 7122143 ynjI Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382460.1 1343066 D 585054 CDS YP_002382461.1 218548670 7121721 complement(1344223..1345566) 1 NC_011740.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1345566 gdhA 7121721 gdhA Escherichia fergusonii ATCC 35469 glutamate dehydrogenase YP_002382461.1 1344223 R 585054 CDS YP_002382462.1 218548671 7123657 1345917..1346192 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1346192 7123657 EFER_1305 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382462.1 1345917 D 585054 CDS YP_002382463.1 218548672 7120342 complement(1346152..1346565) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21101911; Product type e : enzyme; pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase 1346565 nudG 7120342 nudG Escherichia fergusonii ATCC 35469 pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase YP_002382463.1 1346152 R 585054 CDS YP_002382464.1 218548673 7119672 complement(1346677..1346829) 1 NC_011740.1 hypothetical protein 1346829 7119672 EFER_1307 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382464.1 1346677 R 585054 CDS YP_002382465.1 218548674 7120343 1346805..1347425 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type m : membrane component; phosphatidyl transferase, inner membrane protein 1347425 ynjF 7120343 ynjF Escherichia fergusonii ATCC 35469 phosphatidyl transferase, inner membrane protein YP_002382465.1 1346805 D 585054 CDS YP_002382466.1 218548675 7121720 complement(1347434..1348741) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; thiosulfate sulfur transferase / thiosulfate binding protein 1348741 ynjE 7121720 ynjE Escherichia fergusonii ATCC 35469 thiosulfate sulfur transferase / thiosulfate binding protein YP_002382466.1 1347434 R 585054 CDS YP_002382467.1 218548676 7123366 complement(1348808..1349461) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; sulfate/thiosulfate ABC transporter ATP-binding protein 1349461 ynjD 7123366 ynjD Escherichia fergusonii ATCC 35469 sulfate/thiosulfate ABC transporter ATP-binding protein YP_002382467.1 1348808 R 585054 CDS YP_002382468.1 218548677 7121719 complement(1349461..1350951) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter membrane protein 1350951 ynjC 7121719 ynjC Escherichia fergusonii ATCC 35469 ABC transporter membrane protein YP_002382468.1 1349461 R 585054 CDS YP_002382469.1 218548678 7121718 complement(1350969..1352135) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; ABC transporter substrate-binding protein 1352135 ynjB 7121718 ynjB Escherichia fergusonii ATCC 35469 ABC transporter substrate-binding protein YP_002382469.1 1350969 R 585054 CDS YP_002382470.1 218548679 7121717 complement(1352145..1352693) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1352693 ynjA 7121717 ynjA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382470.1 1352145 R 585054 CDS YP_002382471.1 218548680 7121716 complement(1352693..1353397) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1353397 ydjZ 7121716 ydjZ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382471.1 1352693 R 585054 CDS YP_002382472.1 218548681 7122727 complement(1353401..1354105) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1354105 ydjX 7122727 ydjX Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382472.1 1353401 R 585054 CDS YP_002382473.1 218548682 7122726 complement(1354262..1355068) 1 NC_011740.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III 1355068 xthA 7122726 xthA Escherichia fergusonii ATCC 35469 exonuclease III YP_002382473.1 1354262 R 585054 CDS YP_002382474.1 218548683 7122387 1355514..1356734 1 NC_011740.1 catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate; bifunctional succinylornithine transaminase/acetylornithine transaminase 1356734 astC 7122387 astC Escherichia fergusonii ATCC 35469 bifunctional succinylornithine transaminase/acetylornithine transaminase YP_002382474.1 1355514 D 585054 CDS YP_002382475.1 218548684 7123610 1356731..1357765 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14675764, 98361920; Product type e : enzyme; arginine succinyltransferase 1357765 astA 7123610 astA Escherichia fergusonii ATCC 35469 arginine succinyltransferase YP_002382475.1 1356731 D 585054 CDS YP_002382476.1 218548685 7120574 1357762..1359240 1 NC_011740.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH; succinylglutamic semialdehyde dehydrogenase 1359240 astD 7120574 astD Escherichia fergusonii ATCC 35469 succinylglutamic semialdehyde dehydrogenase YP_002382476.1 1357762 D 585054 CDS YP_002382477.1 218548686 7121626 1359237..1360580 1 NC_011740.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation; succinylarginine dihydrolase 1360580 astB 7121626 astB Escherichia fergusonii ATCC 35469 succinylarginine dihydrolase YP_002382477.1 1359237 D 585054 CDS YP_002382478.1 218548687 7120575 1360573..1361541 1 NC_011740.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism; succinylglutamate desuccinylase 1361541 astE 7120575 astE Escherichia fergusonii ATCC 35469 succinylglutamate desuccinylase YP_002382478.1 1360573 D 585054 CDS YP_002382479.1 218548688 7123352 1361871..1362356 1 NC_011740.1 periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP; hypothetical protein 1362356 spy 7123352 spy Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382479.1 1361871 D 585054 CDS YP_002382480.1 218548689 7121812 1362549..1363139 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 21862596; hypothetical protein 1363139 ydjR 7121812 ydjR Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382480.1 1362549 D 585054 CDS YP_002382481.1 218548690 7122725 complement(1363099..1363986) 1 NC_011740.1 3' incision activity; acts with UvrC; nucleotide excision repair endonuclease 1363986 ydjQ 7122725 ydjQ Escherichia fergusonii ATCC 35469 nucleotide excision repair endonuclease YP_002382481.1 1363099 R 585054 CDS YP_002382482.1 218548691 7123524 complement(1364253..1365080) 1 NC_011740.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 1365080 nadE 7123524 nadE Escherichia fergusonii ATCC 35469 NAD synthetase YP_002382482.1 1364253 R 585054 CDS YP_002382483.1 218548692 7120661 1365282..1365620 1 NC_011740.1 osmotically-inducible lipoprotein E; activator of ntr-like gene protein; DNA-binding transcriptional activator OsmE 1365620 osmE 7120661 osmE Escherichia fergusonii ATCC 35469 DNA-binding transcriptional activator OsmE YP_002382483.1 1365282 D 585054 CDS YP_002382484.1 218548693 7123035 1365917..1366237 1 NC_011740.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB 1366237 chbB 7123035 chbB Escherichia fergusonii ATCC 35469 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB YP_002382484.1 1365917 D 585054 CDS YP_002382485.1 218548694 7120881 1366322..1367680 1 NC_011740.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC 1367680 chbC 7120881 chbC Escherichia fergusonii ATCC 35469 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC YP_002382485.1 1366322 D 585054 CDS YP_002382486.1 218548695 7120882 1367733..1368083 1 NC_011740.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA 1368083 chbA 7120882 chbA Escherichia fergusonii ATCC 35469 PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA YP_002382486.1 1367733 D 585054 CDS YP_002382487.1 218548696 7120880 1368091..1368933 1 NC_011740.1 represses the celABCDF-ydjC operon involved in carbon uptake; DNA-binding transcriptional regulator ChbR 1368933 chbR 7120880 chbR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator ChbR YP_002382487.1 1368091 D 585054 CDS YP_002382488.1 218548697 7120885 1369054..1370406 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20042356, 90185127, 9405618; Product type e : enzyme; cryptic phospho-beta-glucosidase 1370406 chbF 7120885 chbF Escherichia fergusonii ATCC 35469 cryptic phospho-beta-glucosidase YP_002382488.1 1369054 D 585054 CDS YP_002382489.1 218548698 7120883 1370419..1371177 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 20042356, 1987146, 2179047, 8121401, 9405618; hypothetical protein 1371177 chbG 7120883 chbG Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382489.1 1370419 D 585054 CDS YP_002382490.1 218548699 7120884 complement(1371224..1373485) 1 NC_011740.1 Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; hydroperoxidase II 1373485 katE 7120884 katE Escherichia fergusonii ATCC 35469 hydroperoxidase II YP_002382490.1 1371224 R 585054 CDS YP_002382491.1 218548700 7120799 1373581..1373730 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1373730 7120799 EFER_1336 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382491.1 1373581 D 585054 CDS YP_002382492.1 218548701 7123686 1373669..1373932 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9427399; Product type cp : cell process; cell division modulator 1373932 cedA 7123686 cedA Escherichia fergusonii ATCC 35469 cell division modulator YP_002382492.1 1373669 D 585054 CDS YP_002382493.1 218548702 7120877 complement(1373979..1375370) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; cation-acid symporter 1375370 ydjN 7120877 ydjN Escherichia fergusonii ATCC 35469 cation-acid symporter YP_002382493.1 1373979 R 585054 CDS YP_002382494.1 218548703 7122724 complement(1375502..1376092) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10760155; Product type pm : membrane component; hypothetical protein 1376092 ydjM 7122724 ydjM Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382494.1 1375502 R 585054 CDS YP_002382495.1 218548704 7122723 complement(1376251..1376919) 1 NC_011740.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate; 2-deoxyglucose-6-phosphatase 1376919 yniC 7122723 yniC Escherichia fergusonii ATCC 35469 2-deoxyglucose-6-phosphatase YP_002382495.1 1376251 R 585054 CDS YP_002382496.1 218548705 7121715 1377068..1377604 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1377604 yniB 7121715 yniB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382496.1 1377068 D 585054 CDS YP_002382497.1 218548706 7121714 complement(1377653..1378513) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; phosphotransferase/kinase 1378513 yniA 7121714 yniA Escherichia fergusonii ATCC 35469 phosphotransferase/kinase YP_002382497.1 1377653 R 585054 CDS YP_002382498.1 218548707 7123365 complement(1378623..1378934) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1378934 7123365 EFER_1343 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382498.1 1378623 R 585054 CDS YP_002382499.1 218548708 7123142 complement(1379001..1379933) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 78194149, 88292964, 6235149, 6310120; Product type e : enzyme; 6-phosphofructokinase 1379933 pfkB 7123142 pfkB Escherichia fergusonii ATCC 35469 6-phosphofructokinase YP_002382499.1 1379001 R 585054 CDS YP_002382500.1 218548709 7122582 1380221..1380979 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1380979 ydiY 7122582 ydiY Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382500.1 1380221 D 585054 CDS YP_002382501.1 218548710 7122721 1381471..1383399 1 NC_011740.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 1383399 thrS 7122721 thrS Escherichia fergusonii ATCC 35469 threonyl-tRNA synthetase YP_002382501.1 1381471 D 585054 CDS YP_002382502.1 218548711 7120739 1384042..1384239 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93085722, 10094780, 3298224, 3542048, 6325158; Product type s : structure; 50S ribosomal protein L35 1384239 rpmI 7120739 rpmI Escherichia fergusonii ATCC 35469 50S ribosomal protein L35 YP_002382502.1 1384042 D 585054 CDS YP_002382503.1 218548712 7121118 1384292..1384648 1 NC_011740.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 1384648 rplT 7121118 rplT Escherichia fergusonii ATCC 35469 50S ribosomal protein L20 YP_002382503.1 1384292 D 585054 CDS YP_002382505.1 218548714 7122593 1385099..1386082 1 NC_011740.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1386082 pheS 7122593 pheS Escherichia fergusonii ATCC 35469 phenylalanyl-tRNA synthetase subunit alpha YP_002382505.1 1385099 D 585054 CDS YP_002382506.1 218548715 7122595 1386097..1388484 1 NC_011740.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 1388484 pheT 7122595 pheT Escherichia fergusonii ATCC 35469 phenylalanyl-tRNA synthetase subunit beta YP_002382506.1 1386097 D 585054 CDS YP_002382507.1 218548716 7123505 1388489..1388788 1 NC_011740.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 1388788 ihfA 7123505 ihfA Escherichia fergusonii ATCC 35469 integration host factor subunit alpha YP_002382507.1 1388489 D 585054 CDS YP_002382508.1 218548717 7120724 1388889..1389869 1 NC_011740.1 with BtuD and BtuF transports vitamin B12 into the cell; vtamin B12-transporter permease 1389869 btuC 7120724 btuC Escherichia fergusonii ATCC 35469 vtamin B12-transporter permease YP_002382508.1 1388889 D 585054 CDS YP_002382509.1 218548718 7123907 1389873..1390622 1 NC_011740.1 ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell; vitamin B12-transporter ATPase 1390622 btuD 7123907 btuD Escherichia fergusonii ATCC 35469 vitamin B12-transporter ATPase YP_002382509.1 1389873 D 585054 CDS YP_002382510.1 218548719 7121681 1390700..1391164 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12620121; Product type lp : lipoprotein; peptidase lipoprotein 1391164 nlpC 7121681 nlpC Escherichia fergusonii ATCC 35469 peptidase lipoprotein YP_002382510.1 1390700 D 585054 CDS YP_002382511.1 218548720 7120698 1391365..1392120 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1392120 7120698 EFER_1357 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382511.1 1391365 D 585054 CDS YP_002382512.1 218548721 7120344 1392186..1393628 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1393628 ydiU 7120344 ydiU Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382512.1 1392186 D 585054 CDS YP_002382513.1 218548722 7122720 complement(1393630..1393827) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1393827 7122720 EFER_1359 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382513.1 1393630 R 585054 CDS YP_002382514.1 218548723 7123687 complement(1393954..1395000) 1 NC_011740.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase 1395000 aroH 7123687 aroH Escherichia fergusonii ATCC 35469 phospho-2-dehydro-3-deoxyheptonate aldolase YP_002382514.1 1393954 R 585054 CDS YP_002382515.1 218548724 7120550 complement(1395283..1396116) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1396116 ydiA 7120550 ydiA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382515.1 1395283 R 585054 CDS YP_002382516.1 218548725 7122716 1396452..1398830 1 NC_011740.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase 1398830 pps 7122716 pps Escherichia fergusonii ATCC 35469 phosphoenolpyruvate synthase YP_002382516.1 1396452 D 585054 CDS YP_002382517.1 218548726 7120117 complement(1398901..1399404) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1399404 7120117 EFER_1363 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382517.1 1398901 R 585054 CDS YP_002382518.1 218548727 7121125 complement(1399647..1400759) 1 NC_011740.1 YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function; inner membrane protein 1400759 ydiK 7121125 ydiK Escherichia fergusonii ATCC 35469 inner membrane protein YP_002382518.1 1399647 R 585054 CDS YP_002382519.1 218548728 7122719 1401028..1404084 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11102686; Product type pe : enzyme; hypothetical protein 1404084 ydiJ 7122719 ydiJ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382519.1 1401028 D 585054 CDS YP_002382520.1 218548729 7122718 1404081..1404491 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15808744; Product type pe : enzyme; esterase 1404491 ydiI 7122718 ydiI Escherichia fergusonii ATCC 35469 esterase YP_002382520.1 1404081 D 585054 CDS YP_002382521.1 218548730 7124093 1405132..1405500 1 NC_011740.1 functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein; iron-sulfur cluster assembly scaffold protein 1405500 sufA 7124093 sufA Escherichia fergusonii ATCC 35469 iron-sulfur cluster assembly scaffold protein YP_002382521.1 1405132 D 585054 CDS YP_002382522.1 218548731 7121959 1405509..1406996 1 NC_011740.1 with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB 1406996 sufB 7121959 sufB Escherichia fergusonii ATCC 35469 cysteine desulfurase activator complex subunit SufB YP_002382522.1 1405509 D 585054 CDS YP_002382523.1 218548732 7121960 1407006..1407752 1 NC_011740.1 part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; cysteine desulfurase ATPase 1407752 sufC 7121960 sufC Escherichia fergusonii ATCC 35469 cysteine desulfurase ATPase YP_002382523.1 1407006 D 585054 CDS YP_002382524.1 218548733 7121961 1407727..1408998 1 NC_011740.1 with SufBC activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufD 1408998 sufD 7121961 sufD Escherichia fergusonii ATCC 35469 cysteine desulfurase activator complex subunit SufD YP_002382524.1 1407727 D 585054 CDS YP_002382525.1 218548734 7121962 1408995..1410215 1 NC_011740.1 catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine; bifunctional cysteine desulfurase/selenocysteine lyase 1410215 sufS 7121962 sufS Escherichia fergusonii ATCC 35469 bifunctional cysteine desulfurase/selenocysteine lyase YP_002382525.1 1408995 D 585054 CDS YP_002382526.1 218548735 7123954 1410228..1410644 1 NC_011740.1 Acts with SufS to catalyze the formation of L-alanine from L-cysteine; cysteine desufuration protein SufE 1410644 sufE 7123954 sufE Escherichia fergusonii ATCC 35469 cysteine desufuration protein SufE YP_002382526.1 1410228 D 585054 CDS YP_002382527.1 218548736 7121963 1410793..1411794 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1411794 ynhG 7121963 ynhG Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382527.1 1410793 D 585054 CDS YP_002382528.1 218548737 7121713 complement(1411848..1412084) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 334727, 338599, 322142, 353292, 391404, 4261992, 4575979, 6765942; Product type lp : lipoprotein; murein lipoprotein 1412084 lpp 7121713 lpp Escherichia fergusonii ATCC 35469 murein lipoprotein YP_002382528.1 1411848 R 585054 CDS YP_002382529.1 218548738 7120851 complement(1412393..1413805) 1 NC_011740.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1413805 pykF 7120851 pykF Escherichia fergusonii ATCC 35469 pyruvate kinase YP_002382529.1 1412393 R 585054 CDS YP_002382530.1 218548739 7124023 1414319..1414528 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1414528 ydhZ 7124023 ydhZ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382530.1 1414319 D 585054 CDS YP_002382531.1 218548740 7122715 complement(1414567..1416177) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 1416177 ydhS 7122715 ydhS Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382531.1 1414567 R 585054 CDS YP_002382532.1 218548741 7122714 complement(1416338..1416643) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1416643 ydhR 7122714 ydhR Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382532.1 1416338 R 585054 CDS YP_002382533.1 218548742 7120079 complement(1417061..1418434) 1 NC_011740.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein 1418434 mdtK 7120079 mdtK Escherichia fergusonii ATCC 35469 multidrug efflux protein YP_002382533.1 1417061 R 585054 CDS YP_002382534.1 218548743 7121254 1418652..1419299 1 NC_011740.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1419299 ribC 7121254 ribC Escherichia fergusonii ATCC 35469 riboflavin synthase subunit alpha YP_002382534.1 1418652 D 585054 CDS YP_002382535.1 218548744 7121406 complement(1419340..1420488) 1 NC_011740.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge; cyclopropane-fatty-acyl-phospholipid synthase 1420488 cfa 7121406 cfa Escherichia fergusonii ATCC 35469 cyclopropane-fatty-acyl-phospholipid synthase YP_002382535.1 1419340 R 585054 CDS YP_002382536.1 218548745 7120878 complement(1420778..1421983) 1 NC_011740.1 uncharacterized member of the major facilitator superfamily (MFS); inner membrane transport protein YdhC 1421983 ydhC 7120878 ydhC Escherichia fergusonii ATCC 35469 inner membrane transport protein YdhC YP_002382536.1 1420778 R 585054 CDS YP_002382537.1 218548746 7123521 1422097..1423029 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2404765; Product type pr : regulator; DNA-binding transcriptional regulator 1423029 ydhB 7123521 ydhB Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YP_002382537.1 1422097 D 585054 CDS YP_002382538.1 218548747 7122708 complement(1423026..1424051) 1 NC_011740.1 binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR 1424051 purR 7122708 purR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional repressor PurR YP_002382538.1 1423026 R 585054 CDS YP_002382539.1 218548748 7122327 1424605..1425771 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; efflux protein 1425771 ydhP 7122327 ydhP Escherichia fergusonii ATCC 35469 efflux protein YP_002382539.1 1424605 D 585054 CDS YP_002382540.1 218548749 7123523 complement(1425817..1426398) 1 NC_011740.1 SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals; superoxide dismutase 1426398 sodB 7123523 sodB Escherichia fergusonii ATCC 35469 superoxide dismutase YP_002382540.1 1425817 R 585054 CDS YP_002382541.1 218548750 7121797 complement(1426604..1427443) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1427443 7121797 EFER_1389 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382541.1 1426604 R 585054 CDS YP_002382542.1 218548751 7120346 1427770..1428114 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15833738, 15840565, 11950925, 12730244; Product type e : enzyme; hypothetical protein 1428114 ydhD 7120346 ydhD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382542.1 1427770 D 585054 CDS YP_002382543.1 218548752 7122709 complement(1428207..1432829) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; ATP-dependent helicase lhr 1432829 lhr 7122709 lhr Escherichia fergusonii ATCC 35469 ATP-dependent helicase lhr YP_002382543.1 1428207 R 585054 CDS YP_002382544.1 218548753 7120831 complement(1432917..1433564) 1 NC_011740.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 1433564 rnt 7120831 rnt Escherichia fergusonii ATCC 35469 ribonuclease T YP_002382544.1 1432917 R 585054 CDS YP_002382545.1 218548754 7123318 complement(1433667..1434074) 1 NC_011740.1 Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione; glyoxalase I 1434074 gloA 7123318 gloA Escherichia fergusonii ATCC 35469 glyoxalase I YP_002382545.1 1433667 R 585054 CDS YP_002382546.1 218548755 7123660 complement(1434155..1435252) 1 NC_011740.1 FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide; N-ethylmaleimide reductase 1435252 nemA 7123660 nemA Escherichia fergusonii ATCC 35469 N-ethylmaleimide reductase YP_002382546.1 1434155 R 585054 CDS YP_002382547.1 218548756 7120684 complement(1435289..1435804) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator 1435804 ydhM 7120684 ydhM Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YP_002382547.1 1435289 R 585054 CDS YP_002382548.1 218548757 7124092 1436279..1437175 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; oxidoreductase 1437175 ydhF 7124092 ydhF Escherichia fergusonii ATCC 35469 oxidoreductase YP_002382548.1 1436279 D 585054 CDS YP_002382549.1 218548758 7122710 1437256..1437777 1 NC_011740.1 SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water; superoxide dismutase 1437777 sodC 7122710 sodC Escherichia fergusonii ATCC 35469 superoxide dismutase YP_002382549.1 1437256 D 585054 CDS YP_002382550.1 218548759 7121798 complement(1437778..1439787) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1439787 ydhK 7121798 ydhK Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382550.1 1437778 R 585054 CDS YP_002382551.1 218548760 7122712 complement(1439788..1440654) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12900028; Product type e : enzyme; undecaprenyl pyrophosphate phosphatase 1440654 ydhJ 7122712 ydhJ Escherichia fergusonii ATCC 35469 undecaprenyl pyrophosphate phosphatase YP_002382551.1 1439788 R 585054 CDS YP_002382552.1 218548761 7123522 complement(1440648..1440884) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1440884 ydhI 7123522 ydhI Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382552.1 1440648 R 585054 CDS YP_002382553.1 218548762 7122711 1441082..1441522 1 NC_011740.1 Transcription regulator that can both activate or repress expression; transcriptional regulator SlyA 1441522 slyA 7122711 slyA Escherichia fergusonii ATCC 35469 transcriptional regulator SlyA YP_002382553.1 1441082 D 585054 CDS YP_002382554.1 218548763 7121790 complement(1441568..1442035) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8544813; Product type lp : lipoprotein; outer membrane lipoprotein 1442035 slyB 7121790 slyB Escherichia fergusonii ATCC 35469 outer membrane lipoprotein YP_002382554.1 1441568 R 585054 CDS YP_002382555.1 218548764 7121791 1442309..1443433 1 NC_011740.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 1443433 anmK 7121791 anmK Escherichia fergusonii ATCC 35469 anhydro-N-acetylmuramic acid kinase YP_002382555.1 1442309 D 585054 CDS YP_002382556.1 218548765 7120517 1443471..1443848 1 NC_011740.1 MliC; membrane-bound lysozyme inhibitor of c-type lysozyme; lysozyme inhibitor 1443848 ydhA 7120517 ydhA Escherichia fergusonii ATCC 35469 lysozyme inhibitor YP_002382556.1 1443471 D 585054 CDS YP_002382557.1 218548766 7122707 1443906..1444562 1 NC_011740.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase 1444562 pdxH 7122707 pdxH Escherichia fergusonii ATCC 35469 pyridoxamine 5'-phosphate oxidase YP_002382557.1 1443906 D 585054 CDS YP_002382558.1 218548767 7124063 1444689..1445963 1 NC_011740.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 1445963 tyrS 7124063 tyrS Escherichia fergusonii ATCC 35469 tyrosyl-tRNA synthetase YP_002382558.1 1444689 D 585054 CDS YP_002382559.1 218548768 7123507 1446020..1446880 1 NC_011740.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase 1446880 pdxY 7123507 pdxY Escherichia fergusonii ATCC 35469 pyridoxamine kinase YP_002382559.1 1446020 D 585054 CDS YP_002382560.1 218548769 7123502 complement(1446970..1447572) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95096109, 2185038, 9680481; Product type e : enzyme; glutathionine S-transferase 1447572 gst 7123502 gst Escherichia fergusonii ATCC 35469 glutathionine S-transferase YP_002382560.1 1446970 R 585054 CDS YP_002382561.1 218548770 7120622 complement(1447679..1449184) 1 NC_011740.1 mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation; tripeptide transporter permease 1449184 tppB 7120622 tppB Escherichia fergusonii ATCC 35469 tripeptide transporter permease YP_002382561.1 1447679 R 585054 CDS YP_002382562.1 218548771 7122705 complement(1449785..1450420) 1 NC_011740.1 DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines; endonuclease III 1450420 nth 7122705 nth Escherichia fergusonii ATCC 35469 endonuclease III YP_002382562.1 1449785 R 585054 CDS YP_002382563.1 218548772 7119666 complement(1450420..1451112) 1 NC_011740.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex protein RsxE 1451112 rsxE 7119666 rsxE Escherichia fergusonii ATCC 35469 electron transport complex protein RsxE YP_002382563.1 1450420 R 585054 CDS YP_002382564.1 218548773 7121158 complement(1451115..1451735) 1 NC_011740.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG 1451735 rsxG 7121158 rsxG Escherichia fergusonii ATCC 35469 electron transport complex protein RnfG YP_002382564.1 1451115 R 585054 CDS YP_002382565.1 218548774 7121159 complement(1451739..1452797) 1 NC_011740.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD 1452797 rnfD 7121159 rnfD Escherichia fergusonii ATCC 35469 electron transport complex protein RnfD YP_002382565.1 1451739 R 585054 CDS YP_002382566.1 218548775 7123818 complement(1452798..1454978) 1 NC_011740.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC 1454978 rsxC 7123818 rsxC Escherichia fergusonii ATCC 35469 electron transport complex protein RnfC YP_002382566.1 1452798 R 585054 CDS YP_002382567.1 218548776 7121156 complement(1454971..1455549) 1 NC_011740.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB 1455549 rsxB 7121156 rsxB Escherichia fergusonii ATCC 35469 electron transport complex protein RnfB YP_002382567.1 1454971 R 585054 CDS YP_002382568.1 218548777 7123817 complement(1455549..1456130) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10411911, 10637328, 12773378; Product type pm : membrane component; Na(+)-translocating NADH-quinone reductase subunit E 1456130 rsxA 7123817 rsxA Escherichia fergusonii ATCC 35469 Na(+)-translocating NADH-quinone reductase subunit E YP_002382568.1 1455549 R 585054 CDS YP_002382569.1 218548778 7121155 complement(1456207..1456647) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1456647 7121155 EFER_1417 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382569.1 1456207 R 585054 CDS YP_002382570.1 218548779 7120347 complement(1456739..1456954) 1 NC_011740.1 YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes; oriC-binding nucleoid-associated protein 1456954 ydgT 7120347 ydgT Escherichia fergusonii ATCC 35469 oriC-binding nucleoid-associated protein YP_002382570.1 1456739 R 585054 CDS YP_002382571.1 218548780 7122706 1457588..1458628 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; oxidoreductase 1458628 ydgJ 7122706 ydgJ Escherichia fergusonii ATCC 35469 oxidoreductase YP_002382571.1 1457588 D 585054 CDS YP_002382572.1 218548781 7122704 complement(1458674..1459780) 1 NC_011740.1 catalyzes the formation of inosine from adenosine; adenosine deaminase 1459780 add 7122704 add Escherichia fergusonii ATCC 35469 adenosine deaminase YP_002382572.1 1458674 R 585054 CDS YP_002382573.1 218548782 7122272 complement(1459784..1460956) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1856179, 7665481, 10698925; Product type e : enzyme; C-S lyase 1460956 malY 7122272 malY Escherichia fergusonii ATCC 35469 C-S lyase YP_002382573.1 1459784 R 585054 CDS YP_002382574.1 218548783 7121228 complement(1460966..1461121) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 1856179, 2670898; Product type e : enzyme; hypothetical protein 1461121 7121228 EFER_1422 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382574.1 1460966 R 585054 CDS YP_002382575.1 218548784 7123143 complement(1461222..1462799) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1462799 ydgA 7123143 ydgA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382575.1 1461222 R 585054 CDS YP_002382576.1 218548785 7122699 complement(1462826..1464061) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 82100097, 6397402; Product type e : enzyme; mannose-6-phosphate isomerase 1464061 manA 7122699 manA Escherichia fergusonii ATCC 35469 mannose-6-phosphate isomerase YP_002382576.1 1462826 R 585054 CDS YP_002382577.1 218548786 7123831 1464197..1465843 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88193096, 88268900, 92011457, 3005475, 6328431, 9298646; Product type e : enzyme; fumarate hydratase 1465843 fumA 7123831 fumA Escherichia fergusonii ATCC 35469 fumarate hydratase YP_002382577.1 1464197 D 585054 CDS YP_002382578.1 218548787 7120153 1465997..1467400 1 NC_011740.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1467400 fumC 7120153 fumC Escherichia fergusonii ATCC 35469 fumarate hydratase YP_002382578.1 1465997 D 585054 CDS YP_002382579.1 218548788 7120155 complement(1467397..1468326) 1 NC_011740.1 binds to DNA replication terminator sequences to prevent passage of replication forks; DNA replication terminus site-binding protein 1468326 tus 7120155 tus Escherichia fergusonii ATCC 35469 DNA replication terminus site-binding protein YP_002382579.1 1467397 R 585054 CDS YP_002382580.1 218548789 7122606 complement(1468478..1469764) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93086426, 1495392, 1925016, 2646639; Product type r : regulator; sensor protein RstB 1469764 rstB 7122606 rstB Escherichia fergusonii ATCC 35469 sensor protein RstB YP_002382580.1 1468478 R 585054 CDS YP_002382581.1 218548790 7121153 complement(1469777..1470538) 1 NC_011740.1 response regulator in two-component regulatory system with RstB; DNA-binding transcriptional regulator RstA 1470538 rstA 7121153 rstA Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator RstA YP_002382581.1 1469777 R 585054 CDS YP_002382582.1 218548791 7121152 1470621..1470962 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1470962 ydgC 7121152 ydgC Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382582.1 1470621 D 585054 CDS YP_002382583.1 218548792 7122700 complement(1470959..1471681) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14617668; Product type e : enzyme; short chain dehydrogenase 1471681 folM 7122700 folM Escherichia fergusonii ATCC 35469 short chain dehydrogenase YP_002382583.1 1470959 R 585054 CDS YP_002382584.1 218548793 7123005 complement(1471716..1473098) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1311296; Product type pt : transporter; arginine/ornithine antiporter transporter 1473098 ydgI 7123005 ydgI Escherichia fergusonii ATCC 35469 arginine/ornithine antiporter transporter YP_002382584.1 1471716 R 585054 CDS YP_002382585.1 218548794 7122703 complement(1473286..1474230) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1474230 ydgH 7122703 ydgH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382585.1 1473286 R 585054 CDS YP_002382586.1 218548795 7122702 1474735..1476279 1 NC_011740.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha 1476279 pntA 7122702 pntA Escherichia fergusonii ATCC 35469 NAD(P) transhydrogenase subunit alpha YP_002382586.1 1474735 D 585054 CDS YP_002382587.1 218548796 7120094 1476290..1477678 1 NC_011740.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase 1477678 pntB 7120094 pntB Escherichia fergusonii ATCC 35469 pyridine nucleotide transhydrogenase YP_002382587.1 1476290 D 585054 CDS YP_002382588.1 218548797 7123643 1477835..1480003 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1480003 7123643 EFER_1436 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382588.1 1477835 D 585054 CDS YP_002382589.1 218548798 7120348 complement(1479994..1480815) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; metallopeptidase 1480815 ydgD 7120348 ydgD Escherichia fergusonii ATCC 35469 metallopeptidase YP_002382589.1 1479994 R 585054 CDS YP_002382590.1 218548799 7122701 complement(1481085..1481396) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type ph : phenotype; Acid shock protein , protein 1481396 asr 7122701 asr Escherichia fergusonii ATCC 35469 Acid shock protein , protein YP_002382590.1 1481085 R 585054 CDS YP_002382591.1 218548800 7120572 complement(1481916..1483169) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; MFS superfamily transporter 1483169 ynfM 7120572 ynfM Escherichia fergusonii ATCC 35469 MFS superfamily transporter YP_002382591.1 1481916 R 585054 CDS YP_002382592.1 218548801 7121711 1483290..1484189 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator 1484189 ynfL 7121711 ynfL Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YP_002382592.1 1483290 D 585054 CDS YP_002382593.1 218548802 7121710 1484205..1484390 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1484390 7121710 EFER_1441 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382593.1 1484205 D 585054 CDS YP_002382594.1 218548803 7120349 1484318..1485538 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10318813, 20490366, 6989798, 99340206, 99395104, 99398866, 7766024; Product type r : regulator; DNA-binding transcriptional repressor 1485538 dgsA 7120349 dgsA Escherichia fergusonii ATCC 35469 DNA-binding transcriptional repressor YP_002382594.1 1484318 D 585054 CDS YP_002382595.1 218548804 7123550 1485663..1486358 1 NC_011740.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 1486358 ynfK 7123550 ynfK Escherichia fergusonii ATCC 35469 dithiobiotin synthetase YP_002382595.1 1485663 D 585054 CDS YP_002382596.1 218548805 7121709 complement(1486311..1487609) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; voltage-gated ClC-type chloride channel ClcB 1487609 clcB 7121709 clcB Escherichia fergusonii ATCC 35469 voltage-gated ClC-type chloride channel ClcB YP_002382596.1 1486311 R 585054 CDS YP_002382597.1 218548806 7120902 complement(1487708..1488928) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter ATP/GTP-binding protein 1488928 7120902 EFER_1445 Escherichia fergusonii ATCC 35469 ABC transporter ATP/GTP-binding protein YP_002382597.1 1487708 R 585054 CDS YP_002382598.1 218548807 7120350 complement(1488850..1489500) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter membrane protein 1489500 7120350 EFER_1446 Escherichia fergusonii ATCC 35469 ABC transporter membrane protein YP_002382598.1 1488850 R 585054 CDS YP_002382599.1 218548808 7120351 complement(1489510..1490412) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter substrate-binding protein 1490412 7120351 EFER_1447 Escherichia fergusonii ATCC 35469 ABC transporter substrate-binding protein YP_002382599.1 1489510 R 585054 CDS YP_002382600.1 218548809 7120352 complement(1490437..1491171) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter membrane protein 1491171 7120352 EFER_1448 Escherichia fergusonii ATCC 35469 ABC transporter membrane protein YP_002382600.1 1490437 R 585054 CDS YP_002382601.1 218548810 7120353 1491480..1491713 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1491713 ydcY 7120353 ydcY Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382601.1 1491480 D 585054 CDS YP_002382602.1 218548811 7122682 complement(1491714..1492163) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1492163 ydcZ 7122682 ydcZ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382602.1 1491714 R 585054 CDS YP_002382603.1 218548812 7122683 complement(1492163..1492912) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; acyl-CoA N-acyltransferase 1492912 yncA 7122683 yncA Escherichia fergusonii ATCC 35469 acyl-CoA N-acyltransferase YP_002382603.1 1492163 R 585054 CDS YP_002382604.1 218548813 7121698 1492859..1493896 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; oxidoreductase 1493896 yncB 7121698 yncB Escherichia fergusonii ATCC 35469 oxidoreductase YP_002382604.1 1492859 D 585054 CDS YP_002382605.1 218548814 7121699 1494095..1494760 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11004173; Product type pr : regulator; DNA-binding transcriptional regulator 1494760 yncC 7121699 yncC Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YP_002382605.1 1494095 D 585054 CDS YP_002382606.1 218548815 7123362 complement(1494796..1496898) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : receptor; iron outer membrane receptor 1496898 yncD 7123362 yncD Escherichia fergusonii ATCC 35469 iron outer membrane receptor YP_002382606.1 1494796 R 585054 CDS YP_002382607.1 218548816 7121700 1497140..1498201 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1498201 yncE 7121700 yncE Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382607.1 1497140 D 585054 CDS YP_002382608.1 218548817 7121701 complement(1498316..1499815) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 76005443; Product type t : transporter; L-asparagine transporter 1499815 ansP 7121701 ansP Escherichia fergusonii ATCC 35469 L-asparagine transporter YP_002382608.1 1498316 R 585054 CDS YP_002382609.1 218548818 7120520 1500097..1500714 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; glutathione S-transferase-like protein 1500714 yncG 7120520 yncG Escherichia fergusonii ATCC 35469 glutathione S-transferase-like protein YP_002382609.1 1500097 D 585054 CDS YP_002382610.1 218548819 7123910 1501052..1501252 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1501252 7123910 EFER_1458 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382610.1 1501052 D 585054 CDS YP_002382611.1 218548820 7123144 1501274..1501606 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1501606 7123144 EFER_1459 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382611.1 1501274 D 585054 CDS YP_002382612.1 218548821 7120354 1501651..1501971 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1501971 7120354 EFER_1460 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382612.1 1501651 D 585054 CDS YP_002382613.1 218548822 7120355 1502107..1502496 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1502496 7120355 EFER_1461 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382613.1 1502107 D 585054 CDS YP_002382614.1 218548823 7124050 1503949..1504305 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1504305 7124050 EFER_1463 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382614.1 1503949 D 585054 CDS YP_002382615.1 218548824 7123145 1504606..1505088 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1505088 7123145 EFER_1464 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382615.1 1504606 D 585054 CDS YP_002382616.1 218548825 7120357 1505194..1505535 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1505535 7120357 EFER_1465 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382616.1 1505194 D 585054 CDS YP_002382617.1 218548826 7122504 1506866..1507450 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1507450 7122504 EFER_1468 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382617.1 1506866 D 585054 CDS YP_002382618.1 218548827 7123146 complement(1507611..1508180) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1508180 yddH 7123146 yddH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382618.1 1507611 R 585054 CDS YP_002382619.1 218548828 7122687 1508484..1509200 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20267568; Product type e : enzyme; N-hydroxyarylamine O-acetyltransferase 1509200 nhoA 7122687 nhoA Escherichia fergusonii ATCC 35469 N-hydroxyarylamine O-acetyltransferase YP_002382619.1 1508484 D 585054 CDS YP_002382620.1 218548829 7123203 complement(1509296..1510189) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14611652, 15103639, 2233673; hypothetical protein 1510189 yddE 7123203 yddE Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382620.1 1509296 R 585054 CDS YP_002382621.1 218548830 7122685 complement(1510509..1511717) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; mandelate racemase 1511717 7122685 EFER_1473 Escherichia fergusonii ATCC 35469 mandelate racemase YP_002382621.1 1510509 R 585054 CDS YP_002382622.1 218548831 7120358 1511964..1513007 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; lacI family transcriptional regulator 1513007 7120358 EFER_1474 Escherichia fergusonii ATCC 35469 lacI family transcriptional regulator YP_002382622.1 1511964 D 585054 CDS YP_002382623.1 218548832 7120359 1513016..1513297 1 NC_011740.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase 1513297 ydcE 7120359 ydcE Escherichia fergusonii ATCC 35469 4-oxalocrotonate tautomerase YP_002382623.1 1513016 D 585054 CDS YP_002382624.1 218548833 7122672 complement(1513302..1513871) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1513871 yddH 7122672 yddH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382624.1 1513302 R 585054 CDS YP_002382625.1 218548834 7122688 1514046..1514891 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20267568; Product type e : enzyme; N-hydroxyarylamine O-acetyltransferase 1514891 nhoA 7122688 nhoA Escherichia fergusonii ATCC 35469 N-hydroxyarylamine O-acetyltransferase YP_002382625.1 1514046 D 585054 CDS YP_002382626.1 218548835 7120693 complement(1515028..1515831) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator 1515831 7120693 EFER_1478 Escherichia fergusonii ATCC 35469 transcriptional regulator YP_002382626.1 1515028 R 585054 CDS YP_002382627.1 218548836 7120360 1516005..1517207 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3609743, 2449420, 2215699, 3612800; Product type e : enzyme; Muconate cycloisomerase I 1517207 catB 7120360 catB Escherichia fergusonii ATCC 35469 Muconate cycloisomerase I YP_002382627.1 1516005 D 585054 CDS YP_002382628.1 218548837 7120859 1517197..1517487 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2449420, 2926818; Product type e : enzyme; Muconolactone delta-isomerase 1517487 catC 7120859 catC Escherichia fergusonii ATCC 35469 Muconolactone delta-isomerase YP_002382628.1 1517197 D 585054 CDS YP_002382629.1 218548838 7120860 1517552..1518478 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3170486, 10801478; Product type e : enzyme; Catechol 1,2-dioxygenase 1518478 catA 7120860 catA Escherichia fergusonii ATCC 35469 Catechol 1,2-dioxygenase YP_002382629.1 1517552 D 585054 CDS YP_002382630.1 218548839 7123765 1518558..1519940 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1885518, 15514110; Product type e : enzyme; Benzoate 1,2-dioxygenase subunit alpha 1519940 benA 7123765 benA Escherichia fergusonii ATCC 35469 Benzoate 1,2-dioxygenase subunit alpha YP_002382630.1 1518558 D 585054 CDS YP_002382631.1 218548840 7123903 1519940..1520425 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1885518, 15514110; Product type e : enzyme; benzoate 1,2-dioxygenase subunit beta 1520425 benB 7123903 benB Escherichia fergusonii ATCC 35469 benzoate 1,2-dioxygenase subunit beta YP_002382631.1 1519940 D 585054 CDS YP_002382632.1 218548841 7121657 1520432..1521451 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1885518, 15514110; Product type e : enzyme; benzoate 1,2-dioxygenase ferredoxin reductase subunit 1521451 benC 7121657 benC Escherichia fergusonii ATCC 35469 benzoate 1,2-dioxygenase ferredoxin reductase subunit YP_002382632.1 1520432 D 585054 CDS YP_002382633.1 218548842 7121658 1521461..1522234 1 NC_011740.1 catalyzes the degradation of 2-hydro-1,2-dihydroxy benzoate to catechol; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase 1522234 benD 7121658 benD Escherichia fergusonii ATCC 35469 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase YP_002382633.1 1521461 D 585054 CDS YP_002382634.1 218548843 7123904 1522487..1522630 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 1522630 7123904 EFER_1486 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382634.1 1522487 D 585054 CDS YP_002382635.1 218548844 7120361 complement(1522739..1523854) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; outer membrane porin protein 1523854 7120361 EFER_1487 Escherichia fergusonii ATCC 35469 outer membrane porin protein YP_002382635.1 1522739 R 585054 CDS YP_002382636.1 218548845 7120362 complement(1524193..1525017) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12410826; Product type t : transporter; hypothetical protein 1525017 yddG 7120362 yddG Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382636.1 1524193 R 585054 CDS YP_002382637.1 218548846 7122686 1525306..1528353 1 NC_011740.1 Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; formate dehydrogenase-N subunit alpha 1528353 fdnG 7122686 fdnG Escherichia fergusonii ATCC 35469 formate dehydrogenase-N subunit alpha YP_002382637.1 1525306 D 585054 CDS YP_002382638.1 218548847 7119996 1528366..1529250 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 76005553, 90375017, 92332427, 11884747, 1834669; Product type c : carrier; formate dehydrogenase-N, Fe-S subunit beta 1529250 fdnH 7119996 fdnH Escherichia fergusonii ATCC 35469 formate dehydrogenase-N, Fe-S subunit beta YP_002382638.1 1528366 D 585054 CDS YP_002382639.1 218548848 7119997 1529243..1529896 1 NC_011740.1 nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase; formate dehydrogenase-N subunit gamma 1529896 fdnI 7119997 fdnI Escherichia fergusonii ATCC 35469 formate dehydrogenase-N subunit gamma YP_002382639.1 1529243 D 585054 CDS YP_002382640.1 218548849 7122689 complement(1530231..1530509) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1530509 7122689 EFER_1494 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382640.1 1530231 R 585054 CDS YP_002382641.1 218548850 7123147 complement(1530695..1531705) 1 NC_011740.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase 1531705 adhP 7123147 adhP Escherichia fergusonii ATCC 35469 alcohol dehydrogenase YP_002382641.1 1530695 R 585054 CDS YP_002382642.1 218548851 7122275 complement(1531839..1533536) 1 NC_011740.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase 1533536 sfcA 7122275 sfcA Escherichia fergusonii ATCC 35469 malate dehydrogenase YP_002382642.1 1531839 R 585054 CDS YP_002382644.1 218548853 7120363 complement(1533932..1534147) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10498711, 13129944; Product type f : factor; biofilm-dependent modulation protein 1534147 bdm 7120363 bdm Escherichia fergusonii ATCC 35469 biofilm-dependent modulation protein YP_002382644.1 1533932 R 585054 CDS YP_002382645.1 218548854 7121656 1534490..1534921 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14512736, 91350191, 9298646; Product type m : membrane component; osmotically inducible, stress-inducible membrane protein 1534921 osmC 7121656 osmC Escherichia fergusonii ATCC 35469 osmotically inducible, stress-inducible membrane protein YP_002382645.1 1534490 D 585054 CDS YP_002382646.1 218548855 7119702 complement(1535156..1536079) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator 1536079 ydcI 7119702 ydcI Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YP_002382646.1 1535156 R 585054 CDS YP_002382647.1 218548856 7122674 complement(1536269..1536889) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7990141, 3194022, 8407791; Product type e : enzyme; protocatechuate 3,4-dioxygenase subunit alpha 1536889 pcaG 7122674 pcaG Escherichia fergusonii ATCC 35469 protocatechuate 3,4-dioxygenase subunit alpha YP_002382647.1 1536269 R 585054 CDS YP_002382648.1 218548857 7122562 complement(1536886..1537644) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7990141, 3194022, 8407791; Product type e : enzyme; protocatechuate 3,4-dioxygenase subunit beta 1537644 pcaH 7122562 pcaH Escherichia fergusonii ATCC 35469 protocatechuate 3,4-dioxygenase subunit beta YP_002382648.1 1536886 R 585054 CDS YP_002382649.1 218548858 7124061 1537855..1539198 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1539198 ydcJ 7124061 ydcJ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382649.1 1537855 D 585054 CDS YP_002382650.1 218548859 7122675 1539516..1541141 1 NC_011740.1 involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans; glucan biosynthesis protein D 1541141 mdoD 7122675 mdoD Escherichia fergusonii ATCC 35469 glucan biosynthesis protein D YP_002382650.1 1539516 D 585054 CDS YP_002382651.1 218548860 7123835 1541284..1541520 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1541520 ydcH 7123835 ydcH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382651.1 1541284 D 585054 CDS YP_002382652.1 218548861 7122673 1541574..1542122 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2671655; Product type e : enzyme; ribosomal-protein-L7/L12-serine acetyltransferase 1542122 rimL 7122673 rimL Escherichia fergusonii ATCC 35469 ribosomal-protein-L7/L12-serine acetyltransferase YP_002382652.1 1541574 D 585054 CDS YP_002382653.1 218548862 7123864 complement(1542114..1543094) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transferase 1543094 ydcK 7123864 ydcK Escherichia fergusonii ATCC 35469 transferase YP_002382653.1 1542114 R 585054 CDS YP_002382654.1 218548863 7122676 1543310..1543906 1 NC_011740.1 with TehA confers resistance to tellurite; tellurite resistance protein TehB 1543906 tehB 7122676 tehB Escherichia fergusonii ATCC 35469 tellurite resistance protein TehB YP_002382654.1 1543310 D 585054 CDS YP_002382655.1 218548864 7121984 1544049..1544717 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1544717 ydcL 7121984 ydcL Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382655.1 1544049 D 585054 CDS YP_002382656.1 218548865 7124085 1544844..1546805 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; peptidase 1546805 ydcP 7124085 ydcP Escherichia fergusonii ATCC 35469 peptidase YP_002382656.1 1544844 D 585054 CDS YP_002382657.1 218548866 7122678 1547421..1547942 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1547942 7122678 EFER_1511 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382657.1 1547421 D 585054 CDS YP_002382658.1 218548867 7120364 complement(1548036..1548266) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1548266 yncJ 7120364 yncJ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382658.1 1548036 R 585054 CDS YP_002382659.1 218548868 7121702 1548413..1549819 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15223311; Product type pr : regulator; DNA-binding transcriptional regulator 1549819 ydcR 7121702 ydcR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YP_002382659.1 1548413 D 585054 CDS YP_002382660.1 218548869 7124086 1550064..1551209 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11683869; Product type pt : transporter; spermidine/putrescine ABC transporter substrate-binding protein 1551209 ydcS 7124086 ydcS Escherichia fergusonii ATCC 35469 spermidine/putrescine ABC transporter substrate-binding protein YP_002382660.1 1550064 D 585054 CDS YP_002382661.1 218548870 7122679 1551227..1552240 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; spermidine/putrescine ABC transporter ATP-binding protein 1552240 ydcT 7122679 ydcT Escherichia fergusonii ATCC 35469 spermidine/putrescine ABC transporter ATP-binding protein YP_002382661.1 1551227 D 585054 CDS YP_002382662.1 218548871 7122680 1552241..1553182 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; spermidine/putrescine ABC transporter permease 1553182 ydcU 7122680 ydcU Escherichia fergusonii ATCC 35469 spermidine/putrescine ABC transporter permease YP_002382662.1 1552241 D 585054 CDS YP_002382663.1 218548872 7123516 1553172..1553966 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; spermidine/putrescine ABC transporter permease 1553966 ydcV 7123516 ydcV Escherichia fergusonii ATCC 35469 spermidine/putrescine ABC transporter permease YP_002382663.1 1553172 D 585054 CDS YP_002382664.1 218548873 7123517 1553988..1555412 1 NC_011740.1 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation; gamma-aminobutyraldehyde dehydrogenase 1555412 ydcW 7123517 ydcW Escherichia fergusonii ATCC 35469 gamma-aminobutyraldehyde dehydrogenase YP_002382664.1 1553988 D 585054 CDS YP_002382665.1 218548874 7122681 1555834..1556016 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1556016 ydcX 7122681 ydcX Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382665.1 1555834 D 585054 CDS YP_002382666.1 218548875 7124087 complement(1556064..1556369) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1556369 ynfD 7124087 ynfD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382666.1 1556064 R 585054 CDS YP_002382667.1 218548876 7121708 1556474..1557184 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1557184 ynfC 7121708 ynfC Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382667.1 1556474 D 585054 CDS YP_002382668.1 218548877 7123912 complement(1557189..1557749) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94357898; Product type e : enzyme; spermidine N1-acetyltransferase 1557749 speG 7123912 speG Escherichia fergusonii ATCC 35469 spermidine N1-acetyltransferase YP_002382668.1 1557189 R 585054 CDS YP_002382669.1 218548878 7121807 complement(1557780..1558121) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1558121 ynfB 7121807 ynfB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382669.1 1557780 R 585054 CDS YP_002382670.1 218548879 7121707 1558268..1558594 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1558594 ynfA 7121707 ynfA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382670.1 1558268 D 585054 CDS YP_002382671.1 218548880 7121706 1558703..1559917 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 93341455, 94310441; Product type pe : enzyme; enolase/dehydratase 1559917 rspA 7121706 rspA Escherichia fergusonii ATCC 35469 enolase/dehydratase YP_002382671.1 1558703 D 585054 CDS YP_002382672.1 218548881 7123274 1559905..1560948 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7545940; Product type pe : enzyme; dehydrogenase 1560948 rspB 7123274 rspB Escherichia fergusonii ATCC 35469 dehydrogenase YP_002382672.1 1559905 D 585054 CDS YP_002382673.1 218548882 7123275 1560992..1561966 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; TRAP dicarboxylate transporter subunit DctP 1561966 7123275 EFER_1527 Escherichia fergusonii ATCC 35469 TRAP dicarboxylate transporter subunit DctP YP_002382673.1 1560992 D 585054 CDS YP_002382674.1 218548883 7120365 1561997..1562494 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; TRAP dicarboxylate transporter subunit DctQ 1562494 7120365 EFER_1528 Escherichia fergusonii ATCC 35469 TRAP dicarboxylate transporter subunit DctQ YP_002382674.1 1561997 D 585054 CDS YP_002382675.1 218548884 7120366 1562519..1563802 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; TRAP dicarboxylate transporter subunit DctM 1563802 7120366 EFER_1529 Escherichia fergusonii ATCC 35469 TRAP dicarboxylate transporter subunit DctM YP_002382675.1 1562519 D 585054 CDS YP_002382676.1 218548885 7120367 1563862..1564839 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; TRAP dicarboxylate transporter subunit DctP 1564839 dctP 7120367 dctP Escherichia fergusonii ATCC 35469 TRAP dicarboxylate transporter subunit DctP YP_002382676.1 1563862 D 585054 CDS YP_002382677.1 218548886 7122875 1564888..1565364 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; TRAP dicarboxylate transporter subunit DctQ 1565364 7122875 EFER_1531 Escherichia fergusonii ATCC 35469 TRAP dicarboxylate transporter subunit DctQ YP_002382677.1 1564888 D 585054 CDS YP_002382678.1 218548887 7120368 1565277..1566635 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; TRAP dicarboxylate transporter subunit DctM 1566635 7120368 EFER_1532 Escherichia fergusonii ATCC 35469 TRAP dicarboxylate transporter subunit DctM YP_002382678.1 1565277 D 585054 CDS YP_002382679.1 218548888 7120369 1566699..1568186 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; mannonate dehydrogenase 1568186 ydfI 7120369 ydfI Escherichia fergusonii ATCC 35469 mannonate dehydrogenase YP_002382679.1 1566699 D 585054 CDS YP_002382680.1 218548889 7122696 complement(1568275..1568628) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1568628 ydfZ 7122696 ydfZ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382680.1 1568275 R 585054 CDS YP_002382681.1 218548890 7124091 complement(1568782..1569468) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator 1569468 ydfH 7124091 ydfH Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YP_002382681.1 1568782 R 585054 CDS YP_002382682.1 218548891 7123519 complement(1569555..1570301) 1 NC_011740.1 NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine; 3-hydroxy acid dehydrogenase 1570301 ydfG 7123519 ydfG Escherichia fergusonii ATCC 35469 3-hydroxy acid dehydrogenase YP_002382682.1 1569555 R 585054 CDS YP_002382683.1 218548892 7123518 1570398..1572479 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 216006, 8226676; Product type e : enzyme; dipeptidyl carboxypeptidase II 1572479 dcp 7123518 dcp Escherichia fergusonii ATCC 35469 dipeptidyl carboxypeptidase II YP_002382683.1 1570398 D 585054 CDS YP_002382684.1 218548893 7122871 complement(1572523..1573056) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1573056 ydeJ 7122871 ydeJ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382684.1 1572523 R 585054 CDS YP_002382685.1 218548894 7122695 1573211..1573603 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1573603 ydeI 7122695 ydeI Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382685.1 1573211 D 585054 CDS YP_002382686.1 218548895 7122694 1573742..1574707 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1574707 ydeH 7122694 ydeH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382686.1 1573742 D 585054 CDS YP_002382687.1 218548896 7122693 complement(1574919..1576106) 1 NC_011740.1 YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters; MFS-type transporter YdeE 1576106 ydeE 7122693 ydeE Escherichia fergusonii ATCC 35469 MFS-type transporter YdeE YP_002382687.1 1574919 R 585054 CDS YP_002382688.1 218548897 7122692 1576299..1577192 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20305052; Product type t : transporter; O-acetylserine/cysteine export protein 1577192 eamA 7122692 eamA Escherichia fergusonii ATCC 35469 O-acetylserine/cysteine export protein YP_002382688.1 1576299 D 585054 CDS YP_002382689.1 218548898 7122932 complement(1577329..1577547) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8383113; Product type t : transporter; hypothetical protein 1577547 marB 7122932 marB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382689.1 1577329 R 585054 CDS YP_002382690.1 218548899 7121234 complement(1577555..1577986) 1 NC_011740.1 transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF; DNA-binding transcriptional activator MarA 1577986 marA 7121234 marA Escherichia fergusonii ATCC 35469 DNA-binding transcriptional activator MarA YP_002382690.1 1577555 R 585054 CDS YP_002382691.1 218548900 7121233 complement(1577959..1578393) 1 NC_011740.1 Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes; DNA-binding transcriptional repressor MarR 1578393 marR 7121233 marR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional repressor MarR YP_002382691.1 1577959 R 585054 CDS YP_002382692.1 218548901 7123834 1578613..1579278 1 NC_011740.1 protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function; multiple drug resistance protein MarC 1579278 marC 7123834 marC Escherichia fergusonii ATCC 35469 multiple drug resistance protein MarC YP_002382692.1 1578613 D 585054 CDS YP_002382693.1 218548902 7123833 complement(1579313..1580506) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10094697, 99369894, 8383113, 10438792; Product type t : transporter; sugar efflux transporter 1580506 ydeA 7123833 ydeA Escherichia fergusonii ATCC 35469 sugar efflux transporter YP_002382693.1 1579313 R 585054 CDS YP_002382694.1 218548903 7122691 complement(1580598..1581464) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator 1581464 yneJ 7122691 yneJ Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YP_002382694.1 1580598 R 585054 CDS YP_002382695.1 218548904 7123364 1581562..1582938 1 NC_011740.1 in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; succinate semialdehyde dehydrogenase 1582938 yneI 7123364 yneI Escherichia fergusonii ATCC 35469 succinate semialdehyde dehydrogenase YP_002382695.1 1581562 D 585054 CDS YP_002382696.1 218548905 7121705 1583014..1583940 1 NC_011740.1 catalyzes the formation of glutamate from glutamine; glutaminase 1583940 yneH 7121705 yneH Escherichia fergusonii ATCC 35469 glutaminase YP_002382696.1 1583014 D 585054 CDS YP_002382697.1 218548906 7121704 1583940..1584296 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1584296 yneG 7121704 yneG Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382697.1 1583940 D 585054 CDS YP_002382698.1 218548907 7123363 1584406..1585839 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; membrane-associated diguanylate cyclase 1585839 yneF 7123363 yneF Escherichia fergusonii ATCC 35469 membrane-associated diguanylate cyclase YP_002382698.1 1584406 D 585054 CDS YP_002382699.1 218548908 7123911 1585988..1587439 1 NC_011740.1 catalyzes the formation of D-tagaturonate from D-altronate; altronate oxidoreductase 1587439 uxaB 7123911 uxaB Escherichia fergusonii ATCC 35469 altronate oxidoreductase YP_002382699.1 1585988 D 585054 CDS YP_002382700.1 218548909 7123513 1587635..1588549 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1588549 yneE 7123513 yneE Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382700.1 1587635 D 585054 CDS YP_002382701.1 218548910 7121703 complement(1588553..1589311) 1 NC_011740.1 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase 1589311 tam 7121703 tam Escherichia fergusonii ATCC 35469 trans-aconitate 2-methyltransferase YP_002382701.1 1588553 R 585054 CDS YP_002382702.1 218548911 7121973 complement(1589400..1590608) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transposase 1590608 ydcM 7121973 ydcM Escherichia fergusonii ATCC 35469 transposase YP_002382702.1 1589400 R 585054 CDS YP_002382703.1 218548912 7122677 complement(1590586..1590732) 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 1590732 7122677 EFER_1557 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382703.1 1590586 R 585054 CDS YP_002382704.1 218548913 7120370 1590616..1590984 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transposase, IS605 family, IS200 group 1590984 7120370 EFER_1558 Escherichia fergusonii ATCC 35469 transposase, IS605 family, IS200 group YP_002382704.1 1590616 D 585054 CDS YP_002382705.1 218548914 7120371 complement(1591117..1591407) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; autoinducer-2 (AI-2) modifying protein LsrG 1591407 lsrG 7120371 lsrG Escherichia fergusonii ATCC 35469 autoinducer-2 (AI-2) modifying protein LsrG YP_002382705.1 1591117 R 585054 CDS YP_002382706.1 218548915 7121211 complement(1591431..1592306) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; aldolase 1592306 lsrF 7121211 lsrF Escherichia fergusonii ATCC 35469 aldolase YP_002382706.1 1591431 R 585054 CDS YP_002382707.1 218548916 7121210 complement(1592333..1593355) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11722742; Product type t : transporter; AI2 ABC transporter periplasmic-binding protein 1593355 lsrB 7121210 lsrB Escherichia fergusonii ATCC 35469 AI2 ABC transporter periplasmic-binding protein YP_002382707.1 1592333 R 585054 CDS YP_002382708.1 218548917 7121207 complement(1593367..1594359) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11722742; Product type t : transporter; AI2 ABC transporter membrane protein 1594359 lsrD 7121207 lsrD Escherichia fergusonii ATCC 35469 AI2 ABC transporter membrane protein YP_002382708.1 1593367 R 585054 CDS YP_002382709.1 218548918 7121209 complement(1594359..1595387) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11722742; Product type t : transporter; AI2 ABC transporter membrane protein 1595387 lsrC 7121209 lsrC Escherichia fergusonii ATCC 35469 AI2 ABC transporter membrane protein YP_002382709.1 1594359 R 585054 CDS YP_002382710.1 218548919 7121208 complement(1595381..1596916) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12657059, 11722742; Product type t : transporter; AI2 ABC transporter ATP-binding protein 1596916 ego 7121208 ego Escherichia fergusonii ATCC 35469 AI2 ABC transporter ATP-binding protein YP_002382710.1 1595381 R 585054 CDS YP_002382711.1 218548920 7122941 1597165..1598118 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16321939, 15601708, 14622426; Product type r : regulator; DNA-binding transcriptional regulator 1598118 lsrR 7122941 lsrR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YP_002382711.1 1597165 D 585054 CDS YP_002382712.1 218548921 7121213 1598197..1599789 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15601708, 14622426; Product type e : enzyme; autoinducer-2 (AI-2) kinase 1599789 lsrK 7121213 lsrK Escherichia fergusonii ATCC 35469 autoinducer-2 (AI-2) kinase YP_002382712.1 1598197 D 585054 CDS YP_002382713.1 218548922 7121212 complement(1599987..1600583) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8253194; Product type pe : enzyme; glutathione S-transferase family protein 1600583 7121212 EFER_1568 Escherichia fergusonii ATCC 35469 glutathione S-transferase family protein YP_002382713.1 1599987 R 585054 CDS YP_002382714.1 218548923 7120372 1601925..1602725 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1602725 7120372 EFER_1569 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382714.1 1601925 D 585054 CDS YP_002382715.1 218548924 7123148 complement(1602900..1604918) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; invasin-like protein; protein 1604918 7123148 EFER_1570 Escherichia fergusonii ATCC 35469 invasin-like protein; protein YP_002382715.1 1602900 R 585054 CDS YP_002382716.1 218548925 7123689 complement(1605041..1605910) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; hypothetical protein 1605910 7123689 EFER_1571 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382716.1 1605041 R 585054 CDS YP_002382717.1 218548926 7120373 1606431..1608086 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; multidrug ABC transporter permease/ATP-binding protein 1608086 yddA 7120373 yddA Escherichia fergusonii ATCC 35469 multidrug ABC transporter permease/ATP-binding protein YP_002382717.1 1606431 D 585054 CDS YP_002382718.1 218548927 7122684 1608123..1610495 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; porin protein 1610495 yddB 7122684 yddB Escherichia fergusonii ATCC 35469 porin protein YP_002382718.1 1608123 D 585054 CDS YP_002382719.1 218548928 7124088 1610545..1613343 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9097039, 9278503, 16738553; Product type pe : enzyme; zinc protease 1613343 pqqL 7124088 pqqL Escherichia fergusonii ATCC 35469 zinc protease YP_002382719.1 1610545 D 585054 CDS YP_002382720.1 218548929 7120121 1613670..1615070 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12912902, 92155241, 92394884, 99406302, 8455549; Product type e : enzyme; glutamate decarboxylase 1615070 gadB 7120121 gadB Escherichia fergusonii ATCC 35469 glutamate decarboxylase YP_002382720.1 1613670 D 585054 CDS YP_002382721.1 218548930 7120162 1615255..1616790 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15795232, 15489450; Product type t : transporter; glutamate:gamma-aminobutyric acid antiporter 1616790 gadC 7120162 gadC Escherichia fergusonii ATCC 35469 glutamate:gamma-aminobutyric acid antiporter YP_002382721.1 1615255 D 585054 CDS YP_002382722.1 218548931 7123654 1616827..1618251 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10960106; Product type lp : lipoprotein; lipoprotein 1618251 yddW 7123654 yddW Escherichia fergusonii ATCC 35469 lipoprotein YP_002382722.1 1616827 D 585054 CDS YP_002382723.1 218548932 7124089 1618450..1619841 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16497924, 15142243; Product type pe : enzyme; diguanylate cyclase YddV 1619841 yddV 7124089 yddV Escherichia fergusonii ATCC 35469 diguanylate cyclase YddV YP_002382723.1 1618450 D 585054 CDS YP_002382724.1 218548933 7122690 1619866..1622271 1 NC_011740.1 heme-regulated phosphodiesterase with phosphodiesterase activity with cAMP but not with cGMP, bis(p-nitrophenyl) phosphate or p-nitrophenyl phosphate; cAMP phosphodiesterase 1622271 dos 7122690 dos Escherichia fergusonii ATCC 35469 cAMP phosphodiesterase YP_002382724.1 1619866 D 585054 CDS YP_002382725.1 218548934 7122915 complement(1622329..1623462) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15466022, 87172301, 1731906; Product type e : enzyme; alcohol dehydrogenase 1623462 frmA 7122915 frmA Escherichia fergusonii ATCC 35469 alcohol dehydrogenase YP_002382725.1 1622329 R 585054 CDS YP_002382726.1 218548935 7124142 complement(1623479..1623889) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1623889 yohL 7124142 yohL Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382726.1 1623479 R 585054 CDS YP_002382727.1 218548936 7121173 complement(1624023..1624589) 1 NC_011740.1 B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm; cytochrome b561 1624589 cybB 7121173 cybB Escherichia fergusonii ATCC 35469 cytochrome b561 YP_002382727.1 1624023 R 585054 CDS YP_002382728.1 218548937 7122837 1624659..1625741 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9622357, 9019141, 1917845, 3780374; Product type e : enzyme; glyceraldehyde-3-phosphate dehydrogenase 1625741 gapC 7122837 gapC Escherichia fergusonii ATCC 35469 glyceraldehyde-3-phosphate dehydrogenase YP_002382728.1 1624659 D 585054 CDS YP_002382729.1 218548938 7123656 complement(1625791..1626591) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1626591 ydcF 7123656 ydcF Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382729.1 1625791 R 585054 CDS YP_002382730.1 218548939 7124084 complement(1627006..1627863) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1627863 7124084 EFER_1587 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382730.1 1627006 R 585054 CDS YP_002382731.1 218548940 7120374 complement(1628076..1631921) 1 NC_011740.1 involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA 1631921 hrpA 7120374 hrpA Escherichia fergusonii ATCC 35469 ATP-dependent RNA helicase HrpA YP_002382731.1 1628076 R 585054 CDS YP_002382732.1 218548941 7123444 1632179..1632784 1 NC_011740.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds; azoreductase 1632784 azoR 7123444 azoR Escherichia fergusonii ATCC 35469 azoreductase YP_002382732.1 1632179 D 585054 CDS YP_002382733.1 218548942 7121641 complement(1632838..1634130) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; membrane associated phosphatase 1634130 ynbD 7121641 ynbD Escherichia fergusonii ATCC 35469 membrane associated phosphatase YP_002382733.1 1632838 R 585054 CDS YP_002382734.1 218548943 7121696 complement(1634144..1635901) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hydrolase 1635901 ynbC 7121696 ynbC Escherichia fergusonii ATCC 35469 hydrolase YP_002382734.1 1634144 R 585054 CDS YP_002382735.1 218548944 7121695 complement(1635917..1636813) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; membrane associated CTP-phosphosubstrate transferase 1636813 ynbB 7121695 ynbB Escherichia fergusonii ATCC 35469 membrane associated CTP-phosphosubstrate transferase YP_002382735.1 1635917 R 585054 CDS YP_002382736.1 218548945 7121694 complement(1636813..1637418) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1637418 ynbA 7121694 ynbA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382736.1 1636813 R 585054 CDS YP_002382737.1 218548946 7123909 complement(1637589..1639895) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1639895 ydbD 7123909 ydbD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382737.1 1637589 R 585054 CDS YP_002382738.1 218548947 7119959 complement(1639959..1640819) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; oxidoreductase 1640819 ydbC 7119959 ydbC Escherichia fergusonii ATCC 35469 oxidoreductase YP_002382738.1 1639959 R 585054 CDS YP_002382739.1 218548948 7119958 complement(1641062..1641652) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12846838, 9748275; Product type pe : enzyme; hexapeptide repeat acetyltransferase 1641652 paaY 7119958 paaY Escherichia fergusonii ATCC 35469 hexapeptide repeat acetyltransferase YP_002382739.1 1641062 R 585054 CDS YP_002382740.1 218548949 7123496 complement(1641634..1642584) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12846838, 20229831, 9748275; Product type r : regulator; phenylacetic acid degradation DNA-binding transcriptional repressor 1642584 paaX 7123496 paaX Escherichia fergusonii ATCC 35469 phenylacetic acid degradation DNA-binding transcriptional repressor YP_002382740.1 1641634 R 585054 CDS YP_002382741.1 218548950 7122549 complement(1642684..1643997) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12846838, 9748275, 10766858; Product type e : enzyme; phenylacetyl-CoA ligase 1643997 paaK 7122549 paaK Escherichia fergusonii ATCC 35469 phenylacetyl-CoA ligase YP_002382741.1 1642684 R 585054 CDS YP_002382742.1 218548951 7122548 complement(1644024..1645229) 1 NC_011740.1 catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; beta-ketoadipyl CoA thiolase 1645229 paaE 7122548 paaE Escherichia fergusonii ATCC 35469 beta-ketoadipyl CoA thiolase YP_002382742.1 1644024 R 585054 CDS YP_002382743.1 218548952 7119711 complement(1645229..1645651) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16464851, 12846838, 9748275; Product type e : enzyme; phenylacetate pathway hotdog-fold thioesterase 1645651 paaI 7119711 paaI Escherichia fergusonii ATCC 35469 phenylacetate pathway hotdog-fold thioesterase YP_002382743.1 1645229 R 585054 CDS YP_002382744.1 218548953 7122668 complement(1645641..1647068) 1 NC_011740.1 converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation; 3-hydroxyacyl-CoA dehydrogenase 1647068 paaH 7122668 paaH Escherichia fergusonii ATCC 35469 3-hydroxyacyl-CoA dehydrogenase YP_002382744.1 1645641 R 585054 CDS YP_002382745.1 218548954 7119714 complement(1647070..1647858) 1 NC_011740.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 1647858 paaG 7119714 paaG Escherichia fergusonii ATCC 35469 enoyl-CoA hydratase YP_002382745.1 1647070 R 585054 CDS YP_002382746.1 218548955 7119713 complement(1647858..1648625) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12846838, 9748275, 10766858; Product type e : enzyme; enoyl-CoA hydratase-isomerase 1648625 paaF 7119713 paaF Escherichia fergusonii ATCC 35469 enoyl-CoA hydratase-isomerase YP_002382746.1 1647858 R 585054 CDS YP_002382747.1 218548956 7119712 complement(1648622..1649692) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 17259607, 11260461, 12846838, 9748275; Product type e : enzyme; subunit of the phenylacetly-CoA oxygenase/reductase 1649692 paaJ 7119712 paaJ Escherichia fergusonii ATCC 35469 subunit of the phenylacetly-CoA oxygenase/reductase YP_002382747.1 1648622 R 585054 CDS YP_002382748.1 218548957 7124059 complement(1649700..1650197) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12846838, 9748275; Product type pe : enzyme; multicomponent oxygenase/reductase subunit for phenylacetic acid degradation 1650197 paaD 7124059 paaD Escherichia fergusonii ATCC 35469 multicomponent oxygenase/reductase subunit for phenylacetic acid degradation YP_002382748.1 1649700 R 585054 CDS YP_002382749.1 218548958 7123581 complement(1650212..1650958) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12846838, 9748275; Product type pe : enzyme; multicomponent oxygenase/reductase subunit for phenylacetic acid degradation 1650958 paaC 7123581 paaC Escherichia fergusonii ATCC 35469 multicomponent oxygenase/reductase subunit for phenylacetic acid degradation YP_002382749.1 1650212 R 585054 CDS YP_002382750.1 218548959 7119710 complement(1650967..1651254) 1 NC_011740.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation; phenylacetate-CoA oxygenase subunit PaaB 1651254 paaB 7119710 paaB Escherichia fergusonii ATCC 35469 phenylacetate-CoA oxygenase subunit PaaB YP_002382750.1 1650967 R 585054 CDS YP_002382751.1 218548960 7119709 complement(1651266..1652195) 1 NC_011740.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; phenylacetate-CoA oxygenase subunit PaaA 1652195 paaA 7119709 paaA Escherichia fergusonii ATCC 35469 phenylacetate-CoA oxygenase subunit PaaA YP_002382751.1 1651266 R 585054 CDS YP_002382752.1 218548961 7119708 1652480..1654525 1 NC_011740.1 catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase 1654525 maoC 7119708 maoC Escherichia fergusonii ATCC 35469 bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase YP_002382752.1 1652480 D 585054 CDS YP_002382753.1 218548962 7121231 1654579..1654743 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 1654743 7121231 EFER_1610 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382753.1 1654579 D 585054 CDS YP_002382754.1 218548963 7120375 1654773..1657046 1 NC_011740.1 catalyzes the formation of phenylacetaldehyde from 2-phenylethylamine; tyramine oxidase 1657046 tynA 7120375 tynA Escherichia fergusonii ATCC 35469 tyramine oxidase YP_002382754.1 1654773 D 585054 CDS YP_002382755.1 218548964 7122611 complement(1657105..1658604) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96213037, 97263463, 9043126; Product type e : enzyme; phenylacetaldehyde dehydrogenase 1658604 feaB 7122611 feaB Escherichia fergusonii ATCC 35469 phenylacetaldehyde dehydrogenase YP_002382755.1 1657105 R 585054 CDS YP_002382756.1 218548965 7123627 1658840..1659745 1 NC_011740.1 activator of genes involved in phenylacetic acid catabolism; DNA-binding transcriptional activator FeaR 1659745 feaR 7123627 feaR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional activator FeaR YP_002382756.1 1658840 D 585054 CDS YP_002382757.1 218548966 7123628 complement(1659857..1660177) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1660177 7123628 EFER_1614 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382757.1 1659857 R 585054 CDS YP_002382758.1 218548967 7120376 complement(1660234..1660560) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1660560 ydbL 7120376 ydbL Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382758.1 1660234 R 585054 CDS YP_002382759.1 218548968 7124083 complement(1660565..1660750) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; lipoprotein 1660750 ynbE 7124083 ynbE Escherichia fergusonii ATCC 35469 lipoprotein YP_002382759.1 1660565 R 585054 CDS YP_002382760.1 218548969 7121697 complement(1660747..1663386) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1663386 ydbH 7121697 ydbH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382760.1 1660747 R 585054 CDS YP_002382761.1 218548970 7123619 1663595..1664584 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 4297266, 89123040, 90198524, 8349564, 9025293; Product type e : enzyme; fermentative D-lactate dehydrogenase 1664584 ldhA 7123619 ldhA Escherichia fergusonii ATCC 35469 fermentative D-lactate dehydrogenase YP_002382761.1 1663595 D 585054 CDS YP_002382762.1 218548971 7120819 1664686..1665108 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8349564; Product type f : factor; heat-inducible protein 1665108 hslJ 7120819 hslJ Escherichia fergusonii ATCC 35469 heat-inducible protein YP_002382762.1 1664686 D 585054 CDS YP_002382763.1 218548972 7122226 complement(1665105..1665371) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1665371 ydbJ 7122226 ydbJ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382763.1 1665105 R 585054 CDS YP_002382764.1 218548973 7122669 1665481..1666635 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1666635 7122669 EFER_1621 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382764.1 1665481 D 585054 CDS YP_002382765.1 218548974 7120377 1666984..1670508 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9025293; Product type pe : enzyme; 2-oxoacid-flavodoxin 1670508 ydbK 7120377 ydbK Escherichia fergusonii ATCC 35469 2-oxoacid-flavodoxin YP_002382765.1 1666984 D 585054 CDS YP_002382766.1 218548975 7120931 1670850..1671983 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9642192; Product type t : transporter; outer membrane pore protein N, non-specific 1671983 ompN 7120931 ompN Escherichia fergusonii ATCC 35469 outer membrane pore protein N, non-specific YP_002382766.1 1670850 D 585054 CDS YP_002382767.1 218548976 7123577 1672123..1672557 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12732303, 12381839, 11849540, 9298646; Product type f : factor; stress-induced protein, ATP-binding protein 1672557 uspF 7123577 uspF Escherichia fergusonii ATCC 35469 stress-induced protein, ATP-binding protein YP_002382767.1 1672123 D 585054 CDS YP_002382768.1 218548977 7124078 1672827..1673762 1 NC_011740.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 1673762 ydaO 7124078 ydaO Escherichia fergusonii ATCC 35469 C32 tRNA thiolase YP_002382768.1 1672827 D 585054 CDS YP_002382769.1 218548978 7123618 complement(1673875..1675248) 1 NC_011740.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA; ATP-dependent RNA helicase DbpA 1675248 dbpA 7123618 dbpA Escherichia fergusonii ATCC 35469 ATP-dependent RNA helicase DbpA YP_002382769.1 1673875 R 585054 CDS YP_002382770.1 218548979 7122869 complement(1675277..1675450) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1675450 7122869 EFER_1627 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382770.1 1675277 R 585054 CDS YP_002382771.1 218548980 7121683 complement(1675623..1675769) 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 1675769 7121683 EFER_1628 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382771.1 1675623 R 585054 CDS YP_002382772.1 218548981 7123690 complement(1675726..1676709) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; zinc transporter 1676709 zntB 7123690 zntB Escherichia fergusonii ATCC 35469 zinc transporter YP_002382772.1 1675726 R 585054 CDS YP_002382773.1 218548982 7119957 1676942..1678180 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1678180 ydaM 7119957 ydaM Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382773.1 1676942 D 585054 CDS YP_002382774.1 218548983 7119956 complement(1678231..1678638) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2298704; Product type e : enzyme; 4-carboxymuconolactone decarboxylase 1678638 pcaC 7119956 pcaC Escherichia fergusonii ATCC 35469 4-carboxymuconolactone decarboxylase YP_002382774.1 1678231 R 585054 CDS YP_002382775.1 218548984 7122560 complement(1678607..1679422) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 8181753; Product type e : enzyme; 3-oxoadipate enol-lactonase 1679422 pcaD 7122560 pcaD Escherichia fergusonii ATCC 35469 3-oxoadipate enol-lactonase YP_002382775.1 1678607 R 585054 CDS YP_002382776.1 218548985 7122561 complement(1679361..1680716) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1390752; Product type e : enzyme; 3-carboxy-cis,cis-muconate cycloisomerase 1680716 pcaB 7122561 pcaB Escherichia fergusonii ATCC 35469 3-carboxy-cis,cis-muconate cycloisomerase YP_002382776.1 1679361 R 585054 CDS YP_002382777.1 218548986 7123499 complement(1680723..1681925) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9748275; Product type e : enzyme; Beta-ketoadipyl CoA thiolase 1681925 paaJ 7123499 paaJ Escherichia fergusonii ATCC 35469 Beta-ketoadipyl CoA thiolase YP_002382777.1 1680723 R 585054 CDS YP_002382778.1 218548987 7122547 complement(1681935..1682591) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8063101; Product type e : enzyme; 3-oxoadipate CoA-transferase subunit B 1682591 pcaJ 7122547 pcaJ Escherichia fergusonii ATCC 35469 3-oxoadipate CoA-transferase subunit B YP_002382778.1 1681935 R 585054 CDS YP_002382779.1 218548988 7123500 complement(1682602..1683324) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1624453, 6780551; Product type e : enzyme; 3-oxoadipate CoA-transferase subunit A 1683324 pcaI 7123500 pcaI Escherichia fergusonii ATCC 35469 3-oxoadipate CoA-transferase subunit A YP_002382779.1 1682602 R 585054 CDS YP_002382780.1 218548989 7122563 1683462..1684268 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8083169; Product type r : regulator; Pca regulon regulatory protein 1684268 PcaR 7122563 PcaR Escherichia fergusonii ATCC 35469 Pca regulon regulatory protein YP_002382780.1 1683462 D 585054 CDS YP_002382781.1 218548990 7124062 complement(1684269..1684832) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1684832 ydaL 7124062 ydaL Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382781.1 1684269 R 585054 CDS YP_002382782.1 218548991 7120797 1685027..1685542 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88067749, 91161525, 94252990, 98125595, 1520330; Product type e : enzyme; O-6-alkylguanine-DNA:cysteine-protein methyltransferase 1685542 ogt 7120797 ogt Escherichia fergusonii ATCC 35469 O-6-alkylguanine-DNA:cysteine-protein methyltransferase YP_002382782.1 1685027 D 585054 CDS YP_002382783.1 218548992 7119690 1685737..1686489 1 NC_011740.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator 1686489 fnr 7119690 fnr Escherichia fergusonii ATCC 35469 fumarate/nitrate reduction transcriptional regulator YP_002382783.1 1685737 D 585054 CDS YP_002382784.1 218548993 7123000 complement(1686610..1689774) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 391406; Product type pe : enzyme; transposase, transposon Tn3 1689774 7123000 EFER_1641 Escherichia fergusonii ATCC 35469 transposase, transposon Tn3 YP_002382784.1 1686610 R 585054 CDS YP_002382785.1 218548994 7120379 1689743..1690336 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type pe : enzyme; Resolvase transposon Tn3 1690336 7120379 EFER_1642 Escherichia fergusonii ATCC 35469 Resolvase transposon Tn3 YP_002382785.1 1689743 D 585054 CDS YP_002382786.1 218548995 7120380 1690519..1691379 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 358200, 3019092, 15769331; Product type e : enzyme; Beta-lactamase TEM 1691379 bla 7120380 bla Escherichia fergusonii ATCC 35469 Beta-lactamase TEM YP_002382786.1 1690519 D 585054 CDS YP_002382787.1 218548996 7121673 1691595..1692545 1 NC_011740.1 with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE 1692545 uspE 7121673 uspE Escherichia fergusonii ATCC 35469 universal stress protein UspE YP_002382787.1 1691595 D 585054 CDS YP_002382788.1 218548997 7124077 complement(1692597..1692944) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1692944 ynaJ 7124077 ynaJ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382788.1 1692597 R 585054 CDS YP_002382789.1 218548998 7121693 1693096..1694130 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1694130 ynaI 7121693 ynaI Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382789.1 1693096 D 585054 CDS YP_002382790.1 218548999 7121692 complement(1694232..1695845) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10438753, 9495761; Product type t : transporter; murein tripeptide ABC transporter periplasmic-binding protein 1695845 mppA 7121692 mppA Escherichia fergusonii ATCC 35469 murein tripeptide ABC transporter periplasmic-binding protein YP_002382790.1 1694232 R 585054 CDS YP_002382791.1 218549000 7120960 1696015..1696758 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12511517; Product type e : enzyme; murein peptide amidase A 1696758 mpaA 7120960 mpaA Escherichia fergusonii ATCC 35469 murein peptide amidase A YP_002382791.1 1696015 D 585054 CDS YP_002382792.1 218549001 7120958 complement(1696733..1697857) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11747447, 11747448, 7499381; Product type e : enzyme; L-Ala-D/L-Glu epimerase 1697857 ycjG 7120958 ycjG Escherichia fergusonii ATCC 35469 L-Ala-D/L-Glu epimerase YP_002382792.1 1696733 R 585054 CDS YP_002382793.1 218549002 7119954 1697812..1698318 1 NC_011740.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 1698318 tpx 7119954 tpx Escherichia fergusonii ATCC 35469 thiol peroxidase YP_002382793.1 1697812 D 585054 CDS YP_002382794.1 218549003 7122152 complement(1698371..1699912) 1 NC_011740.1 regulates genes involved in the biosynthesis and transport of aromatic amino acids; DNA-binding transcriptional regulator TyrR 1699912 tyrR 7122152 tyrR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator TyrR YP_002382794.1 1698371 R 585054 CDS YP_002382795.1 218549004 7122614 complement(1700060..1701121) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1701121 ycjF 7122614 ycjF Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382795.1 1700060 R 585054 CDS YP_002382796.1 218549005 7123080 complement(1701118..1702515) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1702515 ycjX 7123080 ycjX Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382796.1 1701118 R 585054 CDS YP_002382797.1 218549006 7119955 complement(1702640..1702990) 1 NC_011740.1 rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide; thiosulfate:cyanide sulfurtransferase 1702990 pspE 7119955 pspE Escherichia fergusonii ATCC 35469 thiosulfate:cyanide sulfurtransferase YP_002382797.1 1702640 R 585054 CDS YP_002382798.1 218549007 7124019 complement(1703033..1703254) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91295203, 97303082; Product type ph : phenotype; peripheral inner membrane phage-shock protein 1703254 pspD 7124019 pspD Escherichia fergusonii ATCC 35469 peripheral inner membrane phage-shock protein YP_002382798.1 1703033 R 585054 CDS YP_002382799.1 218549008 7122305 complement(1703263..1703625) 1 NC_011740.1 with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock; DNA-binding transcriptional activator PspC 1703625 pspC 7122305 pspC Escherichia fergusonii ATCC 35469 DNA-binding transcriptional activator PspC YP_002382799.1 1703263 R 585054 CDS YP_002382800.1 218549009 7122304 complement(1703625..1703849) 1 NC_011740.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding; phage shock protein B 1703849 pspB 7122304 pspB Escherichia fergusonii ATCC 35469 phage shock protein B YP_002382800.1 1703625 R 585054 CDS YP_002382801.1 218549010 7123459 complement(1703904..1704572) 1 NC_011740.1 involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF; phage shock protein PspA 1704572 pspA 7123459 pspA Escherichia fergusonii ATCC 35469 phage shock protein PspA YP_002382801.1 1703904 R 585054 CDS YP_002382802.1 218549011 7122303 1704723..1705712 1 NC_011740.1 transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; phage shock protein operon transcriptional activator 1705712 pspF 7122303 pspF Escherichia fergusonii ATCC 35469 phage shock protein operon transcriptional activator YP_002382802.1 1704723 D 585054 CDS YP_002382803.1 218549012 7122306 1705827..1707470 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2109018, 9634580; Product type t : transporter; antimicrobial peptide ABC transporter periplasmic-binding protein 1707470 sapA 7122306 sapA Escherichia fergusonii ATCC 35469 antimicrobial peptide ABC transporter periplasmic-binding protein YP_002382803.1 1705827 D 585054 CDS YP_002382804.1 218549013 7121190 1707467..1708432 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2109018, 9634580; Product type t : transporter; antimicrobial peptide ABC transporter permease 1708432 sapB 7121190 sapB Escherichia fergusonii ATCC 35469 antimicrobial peptide ABC transporter permease YP_002382804.1 1707467 D 585054 CDS YP_002382805.1 218549014 7123825 1708419..1709309 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2109018, 9634580; Product type t : transporter; antimicrobial peptide ABC transporter permease 1709309 sapC 7123825 sapC Escherichia fergusonii ATCC 35469 antimicrobial peptide ABC transporter permease YP_002382805.1 1708419 D 585054 CDS YP_002382806.1 218549015 7121191 1709309..1710301 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2109018, 10720487, 9634580, 1987159; Product type t : transporter; antimicrobial peptide ABC transporter ATP-binding protein 1710301 sapD 7121191 sapD Escherichia fergusonii ATCC 35469 antimicrobial peptide ABC transporter ATP-binding protein YP_002382806.1 1709309 D 585054 CDS YP_002382807.1 218549016 7121192 1710303..1711109 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2109018, 10720487, 9634580; Product type t : transporter; antimicrobial peptide ABC transporter ATP-binding protein 1711109 sapF 7121192 sapF Escherichia fergusonii ATCC 35469 antimicrobial peptide ABC transporter ATP-binding protein YP_002382807.1 1710303 D 585054 CDS YP_002382808.1 218549017 7123826 1711231..1712019 1 NC_011740.1 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase 1712019 fabI 7123826 fabI Escherichia fergusonii ATCC 35469 enoyl-ACP reductase YP_002382808.1 1711231 D 585054 CDS YP_002382809.1 218549018 7119984 1712241..1713395 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; amidase 1713395 yciW 7119984 yciW Escherichia fergusonii ATCC 35469 amidase YP_002382809.1 1712241 D 585054 CDS YP_002382810.1 218549019 7119952 1713463..1715397 1 NC_011740.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II 1715397 rnb 7119952 rnb Escherichia fergusonii ATCC 35469 exoribonuclease II YP_002382810.1 1713463 D 585054 CDS YP_002382811.1 218549020 7121422 1715621..1717612 1 NC_011740.1 c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP; RNase II stability modulator 1717612 gmr 7121422 gmr Escherichia fergusonii ATCC 35469 RNase II stability modulator YP_002382811.1 1715621 D 585054 CDS YP_002382812.1 218549021 7120595 1717767..1717943 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1717943 7120595 EFER_1669 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382812.1 1717767 D 585054 CDS YP_002382813.1 218549022 7120381 1717912..1718745 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16451192; Product type r : regulator; HTH-type transcriptional regulator 1718745 yciT 7120381 yciT Escherichia fergusonii ATCC 35469 HTH-type transcriptional regulator YP_002382813.1 1717912 D 585054 CDS YP_002382814.1 218549023 7119950 1719020..1719238 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92078100, 2644204; Product type lp : lipoprotein; lipoprotein 1719238 osmB 7119950 osmB Escherichia fergusonii ATCC 35469 lipoprotein YP_002382814.1 1719020 D 585054 CDS YP_002382815.1 218549024 7123580 complement(1719360..1719689) 1 NC_011740.1 involved in start site selection during the initiation of translation; translation initiation factor Sui1 1719689 yciH 7123580 yciH Escherichia fergusonii ATCC 35469 translation initiation factor Sui1 YP_002382815.1 1719360 R 585054 CDS YP_002382816.1 218549025 7119943 complement(1719686..1720423) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87280048, 3052852; Product type e : enzyme; orotidine-5'-phosphate decarboxylase 1720423 pyrF 7119943 pyrF Escherichia fergusonii ATCC 35469 orotidine-5'-phosphate decarboxylase YP_002382816.1 1719686 R 585054 CDS YP_002382817.1 218549026 7124024 complement(1720614..1721783) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1721783 yciM 7124024 yciM Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382817.1 1720614 R 585054 CDS YP_002382818.1 218549027 7119945 complement(1721790..1722098) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1722098 yciS 7119945 yciS Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382818.1 1721790 R 585054 CDS YP_002382819.1 218549028 7119949 complement(1722249..1723043) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89033893, 92104964; Product type e : enzyme; phosphatidylglycerophosphatase B 1723043 pgpB 7119949 pgpB Escherichia fergusonii ATCC 35469 phosphatidylglycerophosphatase B YP_002382819.1 1722249 R 585054 CDS YP_002382820.1 218549029 7122591 1723202..1723798 1 NC_011740.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 1723798 ribA 7122591 ribA Escherichia fergusonii ATCC 35469 GTP cyclohydrolase II YP_002382820.1 1723202 D 585054 CDS YP_002382821.1 218549030 7123316 complement(1723859..1726534) 1 NC_011740.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1726534 acnA 7123316 acnA Escherichia fergusonii ATCC 35469 aconitate hydratase YP_002382821.1 1723859 R 585054 CDS YP_002382822.1 218549031 7122260 1726907..1727074 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1727074 7122260 EFER_1679 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382822.1 1726907 D 585054 CDS YP_002382823.1 218549032 7123691 complement(1727095..1727265) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1727265 7123691 EFER_1680 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382823.1 1727095 R 585054 CDS YP_002382824.1 218549033 7120382 complement(1727266..1727451) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1727451 yciX 7120382 yciX Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382824.1 1727266 R 585054 CDS YP_002382825.1 218549034 7119953 complement(1727715..1728689) 1 NC_011740.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB 1728689 cysB 7119953 cysB Escherichia fergusonii ATCC 35469 transcriptional regulator CysB YP_002382825.1 1727715 R 585054 CDS YP_002382826.1 218549035 7122846 complement(1728898..1731495) 1 NC_011740.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1731495 topA 7122846 topA Escherichia fergusonii ATCC 35469 DNA topoisomerase I YP_002382826.1 1728898 R 585054 CDS YP_002382827.1 218549036 7123432 1731877..1732128 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3029379, 7567469, 9868784; hypothetical protein 1732128 yciN 7123432 yciN Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382827.1 1731877 D 585054 CDS YP_002382828.1 218549037 7119946 complement(1732163..1733212) 1 NC_011740.1 SohB; periplasmic protein; member of the peptidase S49 family; periplasmic protease 1733212 sohB 7119946 sohB Escherichia fergusonii ATCC 35469 periplasmic protease YP_002382828.1 1732163 R 585054 CDS YP_002382829.1 218549038 7123378 1733436..1734194 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; short chain dehydrogenase 1734194 yciK 7123378 yciK Escherichia fergusonii ATCC 35469 short chain dehydrogenase YP_002382829.1 1733436 D 585054 CDS YP_002382830.1 218549039 7123617 1734191..1734781 1 NC_011740.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase 1734781 btuR 7123617 btuR Escherichia fergusonii ATCC 35469 cob(I)yrinic acid a,c-diamide adenosyltransferase YP_002382830.1 1734191 D 585054 CDS YP_002382831.1 218549040 7121682 complement(1734889..1735764) 1 NC_011740.1 catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; 23S rRNA pseudouridylate synthase B 1735764 rluB 7121682 rluB Escherichia fergusonii ATCC 35469 23S rRNA pseudouridylate synthase B YP_002382831.1 1734889 R 585054 CDS YP_002382832.1 218549041 7121417 complement(1735977..1737872) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1737872 yciQ 7121417 yciQ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382832.1 1735977 R 585054 CDS YP_002382833.1 218549042 7119948 complement(1737900..1738520) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1738520 yciO 7119948 yciO Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382833.1 1737900 R 585054 CDS YP_002382834.1 218549043 7119947 complement(1738517..1739398) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1739398 yciV 7119947 yciV Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382834.1 1738517 R 585054 CDS YP_002382836.1 218549045 7122166 1739671..1741233 1 NC_011740.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1741233 trpE 7122166 trpE Escherichia fergusonii ATCC 35469 anthranilate synthase component I YP_002382836.1 1739671 D 585054 CDS YP_002382837.1 218549046 7122165 1741233..1742828 1 NC_011740.1 bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis; bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase 1742828 trpD 7122165 trpD Escherichia fergusonii ATCC 35469 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase YP_002382837.1 1741233 D 585054 CDS YP_002382838.1 218549047 7122164 1742832..1744190 1 NC_011740.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 1744190 trpC 7122164 trpC Escherichia fergusonii ATCC 35469 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase YP_002382838.1 1742832 D 585054 CDS YP_002382839.1 218549048 7123436 1744202..1745395 1 NC_011740.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1745395 trpB 7123436 trpB Escherichia fergusonii ATCC 35469 tryptophan synthase subunit beta YP_002382839.1 1744202 D 585054 CDS YP_002382840.1 218549049 7122163 1745395..1746201 1 NC_011740.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1746201 trpA 7122163 trpA Escherichia fergusonii ATCC 35469 tryptophan synthase subunit alpha YP_002382840.1 1745395 D 585054 CDS YP_002382841.1 218549050 7123991 complement(1746252..1746983) 1 NC_011740.1 receptor for colicin S4; outer membrane protein W 1746983 ompW 7123991 ompW Escherichia fergusonii ATCC 35469 outer membrane protein W YP_002382841.1 1746252 R 585054 CDS YP_002382842.1 218549051 7119694 1747157..1747591 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; ferredoxin 1747591 ykgJ 7119694 ykgJ Escherichia fergusonii ATCC 35469 ferredoxin YP_002382842.1 1747157 D 585054 CDS YP_002382843.1 218549052 7123414 1747618..1748361 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1748361 yciC 7123414 yciC Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382843.1 1747618 D 585054 CDS YP_002382844.1 218549053 7123616 1748392..1748931 1 NC_011740.1 Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 1748931 yciB 7123616 yciB Escherichia fergusonii ATCC 35469 intracellular septation protein A YP_002382844.1 1748392 D 585054 CDS YP_002382845.1 218549054 7119942 1749039..1749437 1 NC_011740.1 YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins; acyl-CoA thioester hydrolase 1749437 yciA 7119942 yciA Escherichia fergusonii ATCC 35469 acyl-CoA thioester hydrolase YP_002382845.1 1749039 D 585054 CDS YP_002382846.1 218549055 7119941 complement(1749482..1750309) 1 NC_011740.1 membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins; transporter 1750309 tonB 7119941 tonB Escherichia fergusonii ATCC 35469 transporter YP_002382846.1 1749482 R 585054 CDS YP_002382847.1 218549056 7123431 1750431..1750727 1 NC_011740.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; YciI-like protein 1750727 yciI 7123431 yciI Escherichia fergusonii ATCC 35469 YciI-like protein YP_002382847.1 1750431 D 585054 CDS YP_002382848.1 218549057 7123693 1751082..1752542 1 NC_011740.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthetase 1752542 cls 7123693 cls Escherichia fergusonii ATCC 35469 cardiolipin synthetase YP_002382848.1 1751082 D 585054 CDS YP_002382849.1 218549058 7120905 1752576..1752905 1 NC_011740.1 highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein 1752905 yciU 7120905 yciU Escherichia fergusonii ATCC 35469 dsDNA-mimic protein YP_002382849.1 1752576 D 585054 CDS YP_002382850.1 218549059 7119951 complement(1753088..1754083) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; voltage-gated potassium channel 1754083 cikL 7119951 cikL Escherichia fergusonii ATCC 35469 voltage-gated potassium channel YP_002382850.1 1753088 R 585054 CDS YP_002382851.1 218549060 7120894 complement(1753987..1754991) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86111606; Product type t : transporter; oligopeptide ABC transporter ATP-binding protein 1754991 oppF 7120894 oppF Escherichia fergusonii ATCC 35469 oligopeptide ABC transporter ATP-binding protein YP_002382851.1 1753987 R 585054 CDS YP_002382852.1 218549061 7119701 complement(1754988..1756001) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86111606; Product type t : transporter; oligopeptide transporter ATP-binding protein 1756001 oppD 7119701 oppD Escherichia fergusonii ATCC 35469 oligopeptide transporter ATP-binding protein YP_002382852.1 1754988 R 585054 CDS YP_002382853.1 218549062 7119700 complement(1756013..1756921) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86111606; Product type t : transporter; oligopeptide ABC transporter membrane protein 1756921 oppC 7119700 oppC Escherichia fergusonii ATCC 35469 oligopeptide ABC transporter membrane protein YP_002382853.1 1756013 R 585054 CDS YP_002382854.1 218549063 7123034 complement(1756936..1757856) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86111606, 93106975, 2187863; Product type t : transporter; oligopeptide transporter permease 1757856 oppB 7123034 oppB Escherichia fergusonii ATCC 35469 oligopeptide transporter permease YP_002382854.1 1756936 R 585054 CDS YP_002382855.1 218549064 7119699 complement(1757941..1759572) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20256410, 86111605, 90256748, 92325017, 2015910, 9298646, 9600841, 2187863, 8740179, 9740056, 10972807; Product type t : transporter; oligopeptide ABC transporter substrate-binding protein 1759572 oppA 7119699 oppA Escherichia fergusonii ATCC 35469 oligopeptide ABC transporter substrate-binding protein YP_002382855.1 1757941 R 585054 CDS YP_002382856.1 218549065 7119698 complement(1760432..1761079) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1761079 ychE 7119698 ychE Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382856.1 1760432 R 585054 CDS YP_002382857.1 218549066 7123076 1761556..1764231 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12783863, 4301680, 89291706, 91200315; Product type e : enzyme; bifunctional acetaldehyde-CoA/alcohol dehydrogenase 1764231 adhE 7123076 adhE Escherichia fergusonii ATCC 35469 bifunctional acetaldehyde-CoA/alcohol dehydrogenase YP_002382857.1 1761556 D 585054 CDS YP_002382858.1 218549067 7120388 complement(1765839..1766492) 1 NC_011740.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1766492 tdk 7120388 tdk Escherichia fergusonii ATCC 35469 thymidine kinase YP_002382858.1 1765839 R 585054 CDS YP_002382859.1 218549068 7123959 1767151..1767564 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89056689, 94335643, 95267838, 95286558, 99355427, 2404280, 11298273; Product type r : regulator; global DNA-binding transcriptional dual regulator H-NS 1767564 hns 7123959 hns Escherichia fergusonii ATCC 35469 global DNA-binding transcriptional dual regulator H-NS YP_002382859.1 1767151 D 585054 CDS YP_002382860.1 218549069 7122205 complement(1767697..1768605) 1 NC_011740.1 together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP--glucose-1-phosphate uridylyltransferase subunit GalU 1768605 galU 7122205 galU Escherichia fergusonii ATCC 35469 UTP--glucose-1-phosphate uridylyltransferase subunit GalU YP_002382860.1 1767697 R 585054 CDS YP_002382861.1 218549070 7120172 complement(1768808..1769869) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339606, 12912910, 9495753; Product type r : regulator; response regulator of RpoS 1769869 rssB 7120172 rssB Escherichia fergusonii ATCC 35469 response regulator of RpoS YP_002382861.1 1768808 R 585054 CDS YP_002382862.1 218549071 7123816 complement(1769913..1770851) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 1770851 rssA 7123816 rssA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382862.1 1769913 R 585054 CDS YP_002382863.1 218549072 7121151 1770932..1771390 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1771390 ychJ 7121151 ychJ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382863.1 1770932 D 585054 CDS YP_002382864.1 218549073 7123077 1771443..1772285 1 NC_011740.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase 1772285 purU 7123077 purU Escherichia fergusonii ATCC 35469 formyltetrahydrofolate deformylase YP_002382864.1 1771443 D 585054 CDS YP_002382865.1 218549074 7121162 complement(1772844..1773935) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8389613; Product type pe : enzyme; Linoleoyl-CoA desaturase 1773935 7121162 EFER_1726 Escherichia fergusonii ATCC 35469 Linoleoyl-CoA desaturase YP_002382865.1 1772844 R 585054 CDS YP_002382866.1 218549075 7120450 complement(1773922..1775046) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1775046 7120450 EFER_1727 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382866.1 1773922 R 585054 CDS YP_002382867.1 218549076 7124082 complement(1775039..1775653) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; acid phosphatase/vanadium-dependent haloperoxidase 1775653 7124082 EFER_1728 Escherichia fergusonii ATCC 35469 acid phosphatase/vanadium-dependent haloperoxidase YP_002382867.1 1775039 R 585054 CDS YP_002382868.1 218549077 7122729 complement(1775638..1776972) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1776972 7122729 EFER_1729 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382868.1 1775638 R 585054 CDS YP_002382869.1 218549078 7122730 complement(1776921..1777727) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1777727 7122730 EFER_1730 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382869.1 1776921 R 585054 CDS YP_002382870.1 218549079 7122731 complement(1777705..1778721) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1778721 7122731 EFER_1731 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382870.1 1777705 R 585054 CDS YP_002382871.1 218549080 7122732 complement(1778718..1779725) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; 3-oxoacyl-ACP synthase 1779725 7122732 EFER_1732 Escherichia fergusonii ATCC 35469 3-oxoacyl-ACP synthase YP_002382871.1 1778718 R 585054 CDS YP_002382872.1 218549081 7122733 complement(1779837..1780514) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 75114694, 89384449, 92121125, 2832376, 3053688; Product type c : carrier; nitrate reductase 1 subunit gamma (cytochrome b(NR)) 1780514 narI 7122733 narI Escherichia fergusonii ATCC 35469 nitrate reductase 1 subunit gamma (cytochrome b(NR)) YP_002382872.1 1779837 R 585054 CDS YP_002382873.1 218549082 7120677 complement(1780514..1781224) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89384449, 92121125, 9632249, 2832376; Product type f : factor; nitrate reductase molybdenum-cofactor-assembly chaperone subunit 1781224 narJ 7120677 narJ Escherichia fergusonii ATCC 35469 nitrate reductase molybdenum-cofactor-assembly chaperone subunit YP_002382873.1 1780514 R 585054 CDS YP_002382874.1 218549083 7123200 complement(1781221..1782759) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 74167294, 89384449, 92121125, 1321049, 2832376, 3053688, 8383531, 8388253, 8664273, 9516445; Product type c : carrier; nitrate reductase 1 subunit, beta (Fe-S) 1782759 narH 7123200 narH Escherichia fergusonii ATCC 35469 nitrate reductase 1 subunit, beta (Fe-S) YP_002382874.1 1781221 R 585054 CDS YP_002382875.1 218549084 7120676 complement(1782756..1786499) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 74167294, 89384449, 92121125, 2233673, 2668029, 2995309, 3053688, 3308846, 6094247; Product type e : enzyme; nitrate reductase 1 subunit alpha 1786499 narG 7120676 narG Escherichia fergusonii ATCC 35469 nitrate reductase 1 subunit alpha YP_002382875.1 1782756 R 585054 CDS YP_002382876.1 218549085 7120675 complement(1786892..1788283) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91258310, 2657652, 2668029; Product type t : transporter; nitrate/nitrite transporter 1788283 narK 7120675 narK Escherichia fergusonii ATCC 35469 nitrate/nitrite transporter YP_002382876.1 1786892 R 585054 CDS YP_002382877.1 218549086 7120678 1788622..1790418 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92276349, 92374842, 94083940, 2649492, 2657652, 2668029; Product type r : regulator; nitrate/nitrite sensor protein NarX 1790418 narX 7120678 narX Escherichia fergusonii ATCC 35469 nitrate/nitrite sensor protein NarX YP_002382877.1 1788622 D 585054 CDS YP_002382878.1 218549087 7120681 1790411..1791061 1 NC_011740.1 two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase; transcriptional regulator NarL 1791061 narL 7120681 narL Escherichia fergusonii ATCC 35469 transcriptional regulator NarL YP_002382878.1 1790411 D 585054 CDS YP_002382879.1 218549088 7120679 complement(1791062..1792315) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7567469; Product type pf : factor; hypothetical protein 1792315 ychP 7120679 ychP Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382879.1 1791062 R 585054 CDS YP_002382880.1 218549089 7123078 1792645..1792998 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1792998 ychN 7123078 ychN Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382880.1 1792645 D 585054 CDS YP_002382881.1 218549090 7119940 complement(1793051..1793746) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type r : regulator; regulatory protein for cation transport 1793746 chaC 7119940 chaC Escherichia fergusonii ATCC 35469 regulatory protein for cation transport YP_002382881.1 1793051 R 585054 CDS YP_002382882.1 218549091 7123234 complement(1793904..1794134) 1 NC_011740.1 in Escherichia coli this protein putatively regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions; cation transport regulator 1794134 chaB 7123234 chaB Escherichia fergusonii ATCC 35469 cation transport regulator YP_002382882.1 1793904 R 585054 CDS YP_002382883.1 218549092 7123233 1794405..1795505 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93266586, 94193576, 94292460; Product type t : transporter; calcium/sodium:proton antiporter 1795505 chaA 7123233 chaA Escherichia fergusonii ATCC 35469 calcium/sodium:proton antiporter YP_002382883.1 1794405 D 585054 CDS YP_002382884.1 218549093 7120879 complement(1795540..1795926) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1795926 7120879 EFER_1745 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382884.1 1795540 R 585054 CDS YP_002382885.1 218549094 7122734 complement(1796155..1797009) 1 NC_011740.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1797009 kdsA 7122734 kdsA Escherichia fergusonii ATCC 35469 2-dehydro-3-deoxyphosphooctonate aldolase YP_002382885.1 1796155 R 585054 CDS YP_002382886.1 218549095 7120808 complement(1797045..1797854) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10322010; Product type pr : regulator; transcriptional regulator 1797854 ychA 7120808 ychA Escherichia fergusonii ATCC 35469 transcriptional regulator YP_002382886.1 1797045 R 585054 CDS YP_002382887.1 218549096 7119936 complement(1797932..1798009) 1 NC_011740.1 hypothetical protein 1798009 7119936 EFER_1748 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382887.1 1797932 R 585054 CDS YP_002382888.1 218549097 7122735 complement(1798061..1798891) 1 NC_011740.1 HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 1798891 prmC 7122735 prmC Escherichia fergusonii ATCC 35469 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_002382888.1 1798061 R 585054 CDS YP_002382889.1 218549098 7120131 complement(1798891..1799973) 1 NC_011740.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1799973 prfA 7120131 prfA Escherichia fergusonii ATCC 35469 peptide chain release factor 1 YP_002382889.1 1798891 R 585054 CDS YP_002382890.1 218549099 7120123 complement(1800015..1801271) 1 NC_011740.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 1801271 hemA 7120123 hemA Escherichia fergusonii ATCC 35469 glutamyl-tRNA reductase YP_002382890.1 1800015 R 585054 CDS YP_002382891.1 218549100 7123727 1801485..1802108 1 NC_011740.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; outer membrane lipoprotein LolB 1802108 lolB 7123727 lolB Escherichia fergusonii ATCC 35469 outer membrane lipoprotein LolB YP_002382891.1 1801485 D 585054 CDS YP_002382892.1 218549101 7120844 1802108..1802959 1 NC_011740.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 1802959 ipk 7120844 ipk Escherichia fergusonii ATCC 35469 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_002382892.1 1802108 D 585054 CDS YP_002382893.1 218549102 7120793 1803110..1804057 1 NC_011740.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1804057 prsA 7120793 prsA Escherichia fergusonii ATCC 35469 ribose-phosphate pyrophosphokinase YP_002382893.1 1803110 D 585054 CDS YP_002382894.1 218549103 7119715 1804182..1805879 1 NC_011740.1 role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport; sulfate transporter YchM 1805879 ychM 7119715 ychM Escherichia fergusonii ATCC 35469 sulfate transporter YchM YP_002382894.1 1804182 D 585054 CDS YP_002382895.1 218549104 7119939 complement(1805936..1806214) 1 NC_011740.1 YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function; hypothetical protein 1806214 ychH 7119939 ychH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382895.1 1805936 R 585054 CDS YP_002382896.1 218549105 7119938 1806488..1807072 1 NC_011740.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1807072 pth 7119938 pth Escherichia fergusonii ATCC 35469 peptidyl-tRNA hydrolase YP_002382896.1 1806488 D 585054 CDS YP_002382897.1 218549106 7122312 1807189..1808280 1 NC_011740.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 1808280 ychF 7122312 ychF Escherichia fergusonii ATCC 35469 GTP-dependent nucleic acid-binding protein EngD YP_002382897.1 1807189 D 585054 CDS YP_002382898.1 218549107 7119937 1808434..1810179 1 NC_011740.1 periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell; trehalase 1810179 treA 7119937 treA Escherichia fergusonii ATCC 35469 trehalase YP_002382898.1 1808434 D 585054 CDS YP_002382899.1 218549108 7122153 complement(1810217..1810471) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; inner membrane protein with transglycosylase-associated domain 1810471 ymgE 7122153 ymgE Escherichia fergusonii ATCC 35469 inner membrane protein with transglycosylase-associated domain YP_002382899.1 1810217 R 585054 CDS YP_002382900.1 218549109 7121690 1810819..1811553 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; regulator 1811553 ycgR 7121690 ycgR Escherichia fergusonii ATCC 35469 regulator YP_002382900.1 1810819 D 585054 CDS YP_002382901.1 218549110 7119935 complement(1811565..1812176) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98317285; Product type e : enzyme; lytic murein endotransglycosylase E 1812176 emtA 7119935 emtA Escherichia fergusonii ATCC 35469 lytic murein endotransglycosylase E YP_002382901.1 1811565 R 585054 CDS YP_002382902.1 218549111 7123560 1812275..1813189 1 NC_011740.1 catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine; L,D-carboxypeptidase A 1813189 ldcA 7123560 ldcA Escherichia fergusonii ATCC 35469 L,D-carboxypeptidase A YP_002382902.1 1812275 D 585054 CDS YP_002382903.1 218549112 7123227 1813286..1815019 1 NC_011740.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter 1815019 cvrA 7123227 cvrA Escherichia fergusonii ATCC 35469 potassium/proton antiporter YP_002382903.1 1813286 D 585054 CDS YP_002382904.1 218549113 7122835 complement(1815068..1816138) 1 NC_011740.1 catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA; alanine racemase 1816138 dadX 7122835 dadX Escherichia fergusonii ATCC 35469 alanine racemase YP_002382904.1 1815068 R 585054 CDS YP_002382905.1 218549114 7122863 complement(1816150..1817448) 1 NC_011740.1 catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 1817448 dadA 7122863 dadA Escherichia fergusonii ATCC 35469 D-amino acid dehydrogenase small subunit YP_002382905.1 1816150 R 585054 CDS YP_002382906.1 218549115 7124116 1817770..1819302 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; SpoVR family protein 1819302 ycgB 7124116 ycgB Escherichia fergusonii ATCC 35469 SpoVR family protein YP_002382906.1 1817770 D 585054 CDS YP_002382907.1 218549116 7119930 complement(1819369..1820088) 1 NC_011740.1 Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator 1820088 fadR 7119930 fadR Escherichia fergusonii ATCC 35469 fatty acid metabolism regulator YP_002382907.1 1819369 R 585054 CDS YP_002382908.1 218549117 7119989 1820310..1821854 1 NC_011740.1 involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter 1821854 nhaB 7119989 nhaB Escherichia fergusonii ATCC 35469 sodium/proton antiporter YP_002382908.1 1820310 D 585054 CDS YP_002382909.1 218549118 7120691 1821996..1822526 1 NC_011740.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B 1822526 dsbB 7120691 dsbB Escherichia fergusonii ATCC 35469 disulfide bond formation protein B YP_002382909.1 1821996 D 585054 CDS YP_002382910.1 218549119 7124127 complement(1822591..1826148) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; attaching and effacing protein, pathogenesis factor 1826148 eaeH 7124127 eaeH Escherichia fergusonii ATCC 35469 attaching and effacing protein, pathogenesis factor YP_002382910.1 1822591 R 585054 CDS YP_002382911.1 218549120 7122931 complement(1826363..1826548) 1 NC_011740.1 hypothetical protein 1826548 7122931 EFER_1772 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382911.1 1826363 R 585054 CDS YP_002382912.1 218549121 7124095 complement(1826615..1827061) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1827061 ycgN 7124095 ycgN Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382912.1 1826615 R 585054 CDS YP_002382913.1 218549122 7119934 complement(1827164..1827823) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15551868; Product type pe : enzyme; hypothetical protein 1827823 ycgM 7119934 ycgM Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382913.1 1827164 R 585054 CDS YP_002382914.1 218549123 7119933 complement(1827874..1828167) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1828167 ycgL 7119933 ycgL Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382914.1 1827874 R 585054 CDS YP_002382915.1 218549124 7119932 1828277..1828999 1 NC_011740.1 blocks the formation of polar Z-ring septums; septum formation inhibitor 1828999 minC 7119932 minC Escherichia fergusonii ATCC 35469 septum formation inhibitor YP_002382915.1 1828277 D 585054 CDS YP_002382916.1 218549125 7123244 1829023..1829835 1 NC_011740.1 ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; cell division inhibitor MinD 1829835 minD 7123244 minD Escherichia fergusonii ATCC 35469 cell division inhibitor MinD YP_002382916.1 1829023 D 585054 CDS YP_002382917.1 218549126 7120933 1829839..1830105 1 NC_011740.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 1830105 minE 7120933 minE Escherichia fergusonii ATCC 35469 cell division topological specificity factor MinE YP_002382917.1 1829839 D 585054 CDS YP_002382918.1 218549127 7123640 complement(1830477..1831085) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ATPase of ABC-type transport system 1831085 7123640 EFER_1779 Escherichia fergusonii ATCC 35469 ATPase of ABC-type transport system YP_002382918.1 1830477 R 585054 CDS YP_002382919.1 218549128 7122736 complement(1831078..1831851) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ATPase of ABC-type transport system 1831851 7122736 EFER_1780 Escherichia fergusonii ATCC 35469 ATPase of ABC-type transport system YP_002382919.1 1831078 R 585054 CDS YP_002382920.1 218549129 7122737 complement(1831845..1832675) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; inner membrane transport protein 1832675 7122737 EFER_1781 Escherichia fergusonii ATCC 35469 inner membrane transport protein YP_002382920.1 1831845 R 585054 CDS YP_002382921.1 218549130 7124096 complement(1832647..1833636) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; inner membrane nickel transport protein 1833636 7124096 EFER_1782 Escherichia fergusonii ATCC 35469 inner membrane nickel transport protein YP_002382921.1 1832647 R 585054 CDS YP_002382922.1 218549131 7122738 complement(1833621..1835207) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; substrate-binding transport protein 1835207 7122738 EFER_1783 Escherichia fergusonii ATCC 35469 substrate-binding transport protein YP_002382922.1 1833621 R 585054 CDS YP_002382923.1 218549132 7122739 complement(1835341..1835601) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1835601 ymgF 7122739 ymgF Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382923.1 1835341 R 585054 CDS YP_002382924.1 218549133 7121691 complement(1835772..1838510) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1838510 7121691 EFER_1785 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382924.1 1835772 R 585054 CDS YP_002382925.1 218549134 7122740 complement(1838898..1840199) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7559343, 1597179; Product type pe : enzyme; Thermostable carboxypeptidase 1 1840199 7122740 EFER_1786 Escherichia fergusonii ATCC 35469 Thermostable carboxypeptidase 1 YP_002382925.1 1838898 R 585054 CDS YP_002382926.1 218549135 7122741 1840567..1840968 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1840968 ycgK 7122741 ycgK Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382926.1 1840567 D 585054 CDS YP_002382927.1 218549136 7119931 complement(1841064..1841780) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1841780 yeeN 7119931 yeeN Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382927.1 1841064 R 585054 CDS YP_002382928.1 218549137 7121547 1842244..1842534 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1842534 7121547 EFER_1789 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382928.1 1842244 D 585054 CDS YP_002382929.1 218549138 7122742 1842932..1846201 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15659678; Product type pf : factor; adhesin yeeJ (fragment) 1846201 7122742 EFER_1790 Escherichia fergusonii ATCC 35469 adhesin yeeJ (fragment) YP_002382929.1 1842932 D 585054 CDS YP_002382930.1 218549139 7122743 1846554..1847036 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; glutathione S-transferase 1847036 7122743 EFER_1791 Escherichia fergusonii ATCC 35469 glutathione S-transferase YP_002382930.1 1846554 D 585054 CDS YP_002382931.1 218549140 7122744 complement(1847374..1848201) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1848201 7122744 EFER_1792 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382931.1 1847374 R 585054 CDS YP_002382932.1 218549141 7120749 complement(1848968..1850218) 1 NC_011740.1 Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 1850218 icd 7120749 icd Escherichia fergusonii ATCC 35469 isocitrate dehydrogenase YP_002382932.1 1848968 R 585054 CDS YP_002382933.1 218549142 7123741 1850390..1851043 1 NC_011740.1 catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase E 1851043 ymfC 7123741 ymfC Escherichia fergusonii ATCC 35469 23S rRNA pseudouridine synthase E YP_002382933.1 1850390 D 585054 CDS YP_002382934.1 218549143 7122055 1851053..1851514 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15292217; Product type e : enzyme; bifunctional thiamin pyrimidine pyrophosphate hydrolase/thiamin pyrophosphate hydrolase 1851514 ymfB 7122055 ymfB Escherichia fergusonii ATCC 35469 bifunctional thiamin pyrimidine pyrophosphate hydrolase/thiamin pyrophosphate hydrolase YP_002382934.1 1851053 D 585054 CDS YP_002382935.1 218549144 7123419 1851568..1852674 1 NC_011740.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1852674 mnmA 7123419 mnmA Escherichia fergusonii ATCC 35469 tRNA-specific 2-thiouridylase MnmA YP_002382935.1 1851568 D 585054 CDS YP_002382936.1 218549145 7123990 1852710..1853351 1 NC_011740.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein 1853351 hflD 7123990 hflD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382936.1 1852710 D 585054 CDS YP_002382937.1 218549146 7122189 1853355..1854725 1 NC_011740.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 1854725 purB 7122189 purB Escherichia fergusonii ATCC 35469 adenylosuccinate lyase YP_002382937.1 1853355 D 585054 CDS YP_002382938.1 218549147 7124021 1854891..1855562 1 NC_011740.1 response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress; DNA-binding transcriptional regulator PhoP 1855562 phoP 7124021 phoP Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator PhoP YP_002382938.1 1854891 D 585054 CDS YP_002382939.1 218549148 7122601 1855562..1857022 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92105017; Product type r : regulator; sensor protein PhoQ 1857022 phoQ 7122601 phoQ Escherichia fergusonii ATCC 35469 sensor protein PhoQ YP_002382939.1 1855562 D 585054 CDS YP_002382940.1 218549149 7122602 1857112..1858233 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1858233 ycfD 7122602 ycfD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382940.1 1857112 D 585054 CDS YP_002382941.1 218549150 7123074 complement(1858282..1859181) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; oxidoreductase 1859181 yeaE 7123074 yeaE Escherichia fergusonii ATCC 35469 oxidoreductase YP_002382941.1 1858282 R 585054 CDS YP_002382942.1 218549151 7121443 complement(1859226..1859972) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10037771, 20267815; Product type f : factor; scaffolding protein for murein synthesizing machinery 1859972 mipA 7121443 mipA Escherichia fergusonii ATCC 35469 scaffolding protein for murein synthesizing machinery YP_002382942.1 1859226 R 585054 CDS YP_002382943.1 218549152 7120936 1860408..1862342 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1862342 yeaG 7120936 yeaG Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382943.1 1860408 D 585054 CDS YP_002382944.1 218549153 7123331 1862455..1863738 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1863738 yeaH 7123331 yeaH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382944.1 1862455 D 585054 CDS YP_002382945.1 218549154 7121506 1864017..1865363 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15919996; Product type m : membrane component; Inner membrane protein yeaI 1865363 yeaI 7121506 yeaI Escherichia fergusonii ATCC 35469 Inner membrane protein yeaI YP_002382945.1 1864017 D 585054 CDS YP_002382946.1 218549155 7121507 1865534..1867036 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 1867036 yeaJ 7121507 yeaJ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382946.1 1865534 D 585054 CDS YP_002382947.1 218549156 7121508 1867079..1867630 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1867630 yeaK 7121508 yeaK Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382947.1 1867079 D 585054 CDS YP_002382948.1 218549157 7122745 1867899..1868345 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1868345 yeaL 7122745 yeaL Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382948.1 1867899 D 585054 CDS YP_002382949.1 218549158 7123879 1868453..1869640 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; MFS superfamily transporter 1869640 yeaN 7123879 yeaN Escherichia fergusonii ATCC 35469 MFS superfamily transporter YP_002382949.1 1868453 D 585054 CDS YP_002382950.1 218549159 7121510 1869695..1870042 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1870042 yeaO 7121510 yeaO Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382950.1 1869695 D 585054 CDS YP_002382951.1 218549160 7123880 complement(1870061..1870318) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1870318 yoaF 7123880 yoaF Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382951.1 1870061 R 585054 CDS YP_002382952.1 218549161 7121724 1870514..1871554 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1871554 yeaP 7121724 yeaP Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382952.1 1870514 D 585054 CDS YP_002382953.1 218549162 7123881 complement(1871813..1872061) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1872061 yeaQ 7123881 yeaQ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382953.1 1871813 R 585054 CDS YP_002382954.1 218549163 7121511 complement(1872227..1872919) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; leucine export protein LeuE 1872919 yeaS 7121511 yeaS Escherichia fergusonii ATCC 35469 leucine export protein LeuE YP_002382954.1 1872227 R 585054 CDS YP_002382955.1 218549164 7121512 complement(1873068..1873607) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 6265208, 7984428; hypothetical protein 1873607 ycfJ 7121512 ycfJ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382955.1 1873068 R 585054 CDS YP_002382956.1 218549165 7119925 complement(1873777..1875081) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14766919, 20130027, 81256452, 92296775, 94042945, 99441207, 6265208; Product type e : enzyme; respiratory NADH dehydrogenase 2/cupric reductase 1875081 ndh 7119925 ndh Escherichia fergusonii ATCC 35469 respiratory NADH dehydrogenase 2/cupric reductase YP_002382956.1 1873777 R 585054 CDS YP_002382957.1 218549166 7120682 complement(1875322..1875864) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1875864 ycfP 7120682 ycfP Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382957.1 1875322 R 585054 CDS YP_002382958.1 218549167 7119927 complement(1875888..1876913) 1 NC_011740.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase 1876913 nagZ 7119927 nagZ Escherichia fergusonii ATCC 35469 beta-hexosaminidase YP_002382958.1 1875888 R 585054 CDS YP_002382959.1 218549168 7120664 complement(1876935..1877747) 1 NC_011740.1 catalyzes the phosphorylation of thiamine to thiamine phosphate; thiamine kinase 1877747 thiK 7120664 thiK Escherichia fergusonii ATCC 35469 thiamine kinase YP_002382959.1 1876935 R 585054 CDS YP_002382960.1 218549169 7121995 complement(1877728..1878369) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; outer membrane lipoprotein 1878369 ycfM 7121995 ycfM Escherichia fergusonii ATCC 35469 outer membrane lipoprotein YP_002382960.1 1877728 R 585054 CDS YP_002382961.1 218549170 7119926 complement(1878383..1878757) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1878757 ycfL 7119926 ycfL Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382961.1 1878383 R 585054 CDS YP_002382962.1 218549171 7123075 complement(1878760..1879119) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15703176, 10493123, 2162465; Product type e : enzyme; purine nucleoside phosphoramidase 1879119 hinT 7123075 hinT Escherichia fergusonii ATCC 35469 purine nucleoside phosphoramidase YP_002382962.1 1878760 R 585054 CDS YP_002382963.1 218549172 7122194 complement(1879455..1880888) 1 NC_011740.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucose-specific transporter subunit IIBC 1880888 ptsG 7122194 ptsG Escherichia fergusonii ATCC 35469 PTS system glucose-specific transporter subunit IIBC YP_002382963.1 1879455 R 585054 CDS YP_002382964.1 218549173 7124020 complement(1881182..1881979) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8505303, 8509334, 10747959; Product type pe : enzyme; metallodependent hydrolase 1881979 ycfH 7124020 ycfH Escherichia fergusonii ATCC 35469 metallodependent hydrolase YP_002382964.1 1881182 R 585054 CDS YP_002382965.1 218549174 7119924 complement(1881990..1882994) 1 NC_011740.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 1882994 holB 7119924 holB Escherichia fergusonii ATCC 35469 DNA polymerase III subunit delta' YP_002382965.1 1881990 R 585054 CDS YP_002382966.1 218549175 7122209 complement(1882991..1883632) 1 NC_011740.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1883632 tmk 7122209 tmk Escherichia fergusonii ATCC 35469 thymidylate kinase YP_002382966.1 1882991 R 585054 CDS YP_002382967.1 218549176 7122136 complement(1883622..1884644) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 1884644 yceG 7122136 yceG Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382967.1 1883622 R 585054 CDS YP_002382968.1 218549177 7119920 complement(1884641..1885456) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1644759, 2071583, 2251281, 10876155; Product type e : enzyme; Aminodeoxychorismate lyase 1885456 pabC 7119920 pabC Escherichia fergusonii ATCC 35469 Aminodeoxychorismate lyase YP_002382968.1 1884641 R 585054 CDS YP_002382969.1 218549178 7123497 complement(1885574..1886815) 1 NC_011740.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 1886815 fabF 7123497 fabF Escherichia fergusonii ATCC 35469 3-oxoacyl-(acyl carrier protein) synthase II YP_002382969.1 1885574 R 585054 CDS YP_002382970.1 218549179 7119981 complement(1886904..1887140) 1 NC_011740.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1887140 acpP 7119981 acpP Escherichia fergusonii ATCC 35469 acyl carrier protein YP_002382970.1 1886904 R 585054 CDS YP_002382971.1 218549180 7122263 complement(1887416..1888150) 1 NC_011740.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1888150 fabG 7122263 fabG Escherichia fergusonii ATCC 35469 3-ketoacyl-ACP reductase YP_002382971.1 1887416 R 585054 CDS YP_002382972.1 218549181 7119982 complement(1888162..1889091) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92052166, 92183950, 92210530, 92234941, 7700236, 7768883, 9298646; Product type e : enzyme; malonyl-CoA-[acyl-carrier-protein] transacylase 1889091 fabD 7119982 fabD Escherichia fergusonii ATCC 35469 malonyl-CoA-[acyl-carrier-protein] transacylase YP_002382972.1 1888162 R 585054 CDS YP_002382973.1 218549182 7119980 complement(1889107..1890060) 1 NC_011740.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 1890060 fabH 7119980 fabH Escherichia fergusonii ATCC 35469 3-oxoacyl-ACP synthase YP_002382973.1 1889107 R 585054 CDS YP_002382974.1 218549183 7119983 complement(1890136..1891212) 1 NC_011740.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 1891212 plsX 7119983 plsX Escherichia fergusonii ATCC 35469 glycerol-3-phosphate acyltransferase PlsX YP_002382974.1 1890136 R 585054 CDS YP_002382975.1 218549184 7120089 complement(1891293..1891466) 1 NC_011740.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1891466 rpmF 7120089 rpmF Escherichia fergusonii ATCC 35469 50S ribosomal protein L32 YP_002382975.1 1891293 R 585054 CDS YP_002382976.1 218549185 7121117 complement(1891518..1892039) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 90008815, 1447160; hypothetical protein 1892039 yceD 7121117 yceD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382976.1 1891518 R 585054 CDS YP_002382977.1 218549186 7123439 1892198..1892821 1 NC_011740.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 1892821 yceF 7123439 yceF Escherichia fergusonii ATCC 35469 Maf-like protein YP_002382977.1 1892198 D 585054 CDS YP_002382978.1 218549187 7119919 complement(1892930..1893925) 1 NC_011740.1 catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C 1893925 rluC 7119919 rluC Escherichia fergusonii ATCC 35469 23S rRNA pseudouridylate synthase C YP_002382978.1 1892930 R 585054 CDS YP_002382979.1 218549188 7121418 1894457..1897636 1 NC_011740.1 bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase; ribonuclease E 1897636 rne 7121418 rne Escherichia fergusonii ATCC 35469 ribonuclease E YP_002382979.1 1894457 D 585054 CDS YP_002382980.1 218549189 7121425 complement(1897784..1898737) 1 NC_011740.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes; flagellar hook-associated protein FlgL 1898737 flgL 7121425 flgL Escherichia fergusonii ATCC 35469 flagellar hook-associated protein FlgL YP_002382980.1 1897784 R 585054 CDS YP_002382981.1 218549190 7122977 complement(1898753..1900399) 1 NC_011740.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 1900399 flgK 7122977 flgK Escherichia fergusonii ATCC 35469 flagellar hook-associated protein FlgK YP_002382981.1 1898753 R 585054 CDS YP_002382982.1 218549191 7122976 complement(1900465..1901406) 1 NC_011740.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; flagellar rod assembly protein/muramidase FlgJ 1901406 flgJ 7122976 flgJ Escherichia fergusonii ATCC 35469 flagellar rod assembly protein/muramidase FlgJ YP_002382982.1 1900465 R 585054 CDS YP_002382983.1 218549192 7122975 complement(1901406..1902503) 1 NC_011740.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 1902503 flgI 7122975 flgI Escherichia fergusonii ATCC 35469 flagellar basal body P-ring protein YP_002382983.1 1901406 R 585054 CDS YP_002382984.1 218549193 7122974 complement(1902515..1903213) 1 NC_011740.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 1903213 flgH 7122974 flgH Escherichia fergusonii ATCC 35469 flagellar basal body L-ring protein YP_002382984.1 1902515 R 585054 CDS YP_002382985.1 218549194 7122973 complement(1903266..1904048) 1 NC_011740.1 makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 1904048 flgG 7122973 flgG Escherichia fergusonii ATCC 35469 flagellar basal body rod protein FlgG YP_002382985.1 1903266 R 585054 CDS YP_002382986.1 218549195 7122972 complement(1904200..1904955) 1 NC_011740.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF 1904955 flgF 7122972 flgF Escherichia fergusonii ATCC 35469 flagellar basal body rod protein FlgF YP_002382986.1 1904200 R 585054 CDS YP_002382987.1 218549196 7122971 complement(1904975..1906180) 1 NC_011740.1 the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 1906180 flgE 7122971 flgE Escherichia fergusonii ATCC 35469 flagellar hook protein FlgE YP_002382987.1 1904975 R 585054 CDS YP_002382988.1 218549197 7123563 complement(1906205..1906900) 1 NC_011740.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production; flagellar basal body rod modification protein 1906900 flgD 7123563 flgD Escherichia fergusonii ATCC 35469 flagellar basal body rod modification protein YP_002382988.1 1906205 R 585054 CDS YP_002382989.1 218549198 7122970 complement(1906912..1907316) 1 NC_011740.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 1907316 flgC 7122970 flgC Escherichia fergusonii ATCC 35469 flagellar basal body rod protein FlgC YP_002382989.1 1906912 R 585054 CDS YP_002382990.1 218549199 7122969 complement(1907320..1907811) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1482109, 89181349; Product type s : structure; flagellar basal-body rod cell-proximal protein 1907811 flgB 7122969 flgB Escherichia fergusonii ATCC 35469 flagellar basal-body rod cell-proximal protein YP_002382990.1 1907320 R 585054 CDS YP_002382991.1 218549200 7122968 1907842..1908552 1 NC_011740.1 required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA 1908552 flgA 7122968 flgA Escherichia fergusonii ATCC 35469 flagellar basal body P-ring biosynthesis protein FlgA YP_002382991.1 1907842 D 585054 CDS YP_002382992.1 218549201 7122967 1908643..1908936 1 NC_011740.1 regulates the flagellar specific sigma28 transcription factor; anti-sigma-28 factor FlgM 1908936 flgM 7122967 flgM Escherichia fergusonii ATCC 35469 anti-sigma-28 factor FlgM YP_002382992.1 1908643 D 585054 CDS YP_002382993.1 218549202 7124136 1908941..1909363 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1655712, 8200538; Product type f : factor; Flagella synthesis protein flgN 1909363 flgN 7124136 flgN Escherichia fergusonii ATCC 35469 Flagella synthesis protein flgN YP_002382993.1 1908941 D 585054 CDS YP_002382994.1 218549203 7124137 complement(1909401..1910978) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1910978 mviN 7124137 mviN Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382994.1 1909401 R 585054 CDS YP_002382995.1 218549204 7123730 complement(1911049..1911972) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; oxidoreductase 1911972 mviM 7123730 mviM Escherichia fergusonii ATCC 35469 oxidoreductase YP_002382995.1 1911049 R 585054 CDS YP_002382996.1 218549205 7120655 complement(1911974..1912648) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1356970, 2828880; hypothetical protein 1912648 yceH 7120655 yceH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382996.1 1911974 R 585054 CDS YP_002382997.1 218549206 7119921 complement(1912630..1913244) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88121676, 90136529, 1356970; Product type e : enzyme; ribosomal-protein-S5-alanine N-acetyltransferase 1913244 rimJ 7119921 rimJ Escherichia fergusonii ATCC 35469 ribosomal-protein-S5-alanine N-acetyltransferase YP_002382997.1 1912630 R 585054 CDS YP_002382998.1 218549207 7121412 1913380..1914666 1 NC_011740.1 Confers resistance to norfloxacin and enoxacin; multidrug resistance protein MdtH 1914666 mdtH 7121412 mdtH Escherichia fergusonii ATCC 35469 multidrug resistance protein MdtH YP_002382998.1 1913380 D 585054 CDS YP_002382999.1 218549208 7121253 1914811..1915371 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; hypothetical protein 1915371 yceB 7121253 yceB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002382999.1 1914811 D 585054 CDS YP_002383000.1 218549209 7119917 1915476..1916522 1 NC_011740.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 1916522 pyrC 7119917 pyrC Escherichia fergusonii ATCC 35469 dihydroorotase YP_002383000.1 1915476 D 585054 CDS YP_002383001.2 229598030 7123464 1916595..1916840 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9606202, 11152126, 11230150, 8682790; Product type f : factor; DNA damage-inducible protein I 1916840 dinI 7123464 dinI Escherichia fergusonii ATCC 35469 DNA damage-inducible protein I YP_002383001.2 1916595 D 585054 CDS YP_002383002.1 218549211 7122900 1917129..1917383 1 NC_011740.1 BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssS 1917383 bssS 7122900 bssS Escherichia fergusonii ATCC 35469 biofilm formation regulatory protein BssS YP_002383002.1 1917129 D 585054 CDS YP_002383003.1 218549212 7121679 1917500..1918615 1 NC_011740.1 catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids; N-methyltryptophan oxidase 1918615 solA 7121679 solA Escherichia fergusonii ATCC 35469 N-methyltryptophan oxidase YP_002383003.1 1917500 D 585054 CDS YP_002383004.1 218549213 7121800 1918989..1919567 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; cytochrome b561 1919567 yceJ 7121800 yceJ Escherichia fergusonii ATCC 35469 cytochrome b561 YP_002383004.1 1918989 D 585054 CDS YP_002383005.1 218549214 7119922 1919564..1920139 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15741337, 11298273, 1840644, 9298646; Product type c : carrier; hypothetical protein 1920139 yceI 7119922 yceI Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383005.1 1919564 D 585054 CDS YP_002383006.1 218549215 7123073 complement(1920189..1921241) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1840644; hypothetical protein 1921241 yceA 7123073 yceA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383006.1 1920189 R 585054 CDS YP_002383007.1 218549216 7119916 1921462..1922382 1 NC_011740.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 1922382 lpxL 7119916 lpxL Escherichia fergusonii ATCC 35469 lipid A biosynthesis lauroyl acyltransferase YP_002383007.1 1921462 D 585054 CDS YP_002383008.1 218549217 7121203 1922565..1923791 1 NC_011740.1 Confers resistance to fosfomycin and deoxycholate; drug efflux system protein MdtG 1923791 mdtG 7121203 mdtG Escherichia fergusonii ATCC 35469 drug efflux system protein MdtG YP_002383008.1 1922565 D 585054 CDS YP_002383009.1 218549218 7123290 1923874..1924248 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 92165719; hypothetical protein 1924248 msyB 7123290 msyB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383009.1 1923874 D 585054 CDS YP_002383010.1 218549219 7120975 complement(1924249..1924476) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; hypothetical protein 1924476 yceK 7120975 yceK Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383010.1 1924249 R 585054 CDS YP_002383011.1 218549220 7119923 complement(1924629..1927172) 1 NC_011740.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space; glucosyltransferase MdoH 1927172 mdoH 7119923 mdoH Escherichia fergusonii ATCC 35469 glucosyltransferase MdoH YP_002383011.1 1924629 R 585054 CDS YP_002383012.1 218549221 7121246 complement(1927165..1928700) 1 NC_011740.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G 1928700 mdoG 7121246 mdoG Escherichia fergusonii ATCC 35469 glucan biosynthesis protein G YP_002383012.1 1927165 R 585054 CDS YP_002383013.1 218549222 7121245 1928744..1928902 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1928902 7121245 EFER_1880 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383013.1 1928744 D 585054 CDS YP_002383014.1 218549223 7122746 1928974..1930134 1 NC_011740.1 required for the transfer of succinyl residues to the glucan backbone; glucans biosynthesis protein 1930134 mdoC 7122746 mdoC Escherichia fergusonii ATCC 35469 glucans biosynthesis protein YP_002383014.1 1928974 D 585054 CDS YP_002383015.1 218549224 7121244 complement(1930142..1931632) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hydrolase 1931632 ymdC 7121244 ymdC Escherichia fergusonii ATCC 35469 hydrolase YP_002383015.1 1930142 R 585054 CDS YP_002383016.1 218549225 7122054 complement(1931565..1932113) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1932113 ymdB 7122054 ymdB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383016.1 1931565 R 585054 CDS YP_002383017.1 218549226 7123417 complement(1932193..1932507) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1932507 ymdA 7123417 ymdA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383017.1 1932193 R 585054 CDS YP_002383018.1 218549227 7122053 complement(1932623..1932955) 1 NC_011740.1 involved in autoagglutination of curliated cells; not involved in production of curli fibers; autoagglutination protein 1932955 csgC 7122053 csgC Escherichia fergusonii ATCC 35469 autoagglutination protein YP_002383018.1 1932623 R 585054 CDS YP_002383019.1 218549228 7122812 complement(1933015..1933473) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89201357, 93023873, 1677357, 8459772, 8817489, 1357528; Product type s : structure; cryptic curlin major subunit 1933473 csgA 7122812 csgA Escherichia fergusonii ATCC 35469 cryptic curlin major subunit YP_002383019.1 1933015 R 585054 CDS YP_002383020.1 218549229 7124106 complement(1933514..1933990) 1 NC_011740.1 CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface; curlin minor subunit 1933990 csgB 7124106 csgB Escherichia fergusonii ATCC 35469 curlin minor subunit YP_002383020.1 1933514 R 585054 CDS YP_002383021.1 218549230 7122811 1934710..1935360 1 NC_011740.1 activates the csgBA and csgDEFG operons involved in biofilm formation; DNA-binding transcriptional regulator CsgD 1935360 csgD 7122811 csgD Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator CsgD YP_002383021.1 1934710 D 585054 CDS YP_002383022.1 218549231 7124107 1935230..1935754 1 NC_011740.1 chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgE 1935754 csgE 7124107 csgE Escherichia fergusonii ATCC 35469 curli assembly protein CsgE YP_002383022.1 1935230 D 585054 CDS YP_002383023.1 218549232 7122813 1935778..1936194 1 NC_011740.1 nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgF 1936194 csgF 7122813 csgF Escherichia fergusonii ATCC 35469 curli assembly protein CsgF YP_002383023.1 1935778 D 585054 CDS YP_002383024.1 218549233 7122814 1936221..1937054 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8817489; Product type lp : lipoprotein; outer membrane lipoprotein 1937054 csgG 7122814 csgG Escherichia fergusonii ATCC 35469 outer membrane lipoprotein YP_002383024.1 1936221 D 585054 CDS YP_002383025.1 218549234 7124108 complement(1937092..1937583) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1937583 ycdZ 7124108 ycdZ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383025.1 1937092 R 585054 CDS YP_002383026.1 218549235 7119915 complement(1937675..1938229) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1938229 ycdY 7119915 ycdY Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383026.1 1937675 R 585054 CDS YP_002383027.1 218549236 7123613 complement(1938253..1938990) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12661000; Product type pe : enzyme; hydrolase 1938990 ycdX 7123613 ycdX Escherichia fergusonii ATCC 35469 hydrolase YP_002383027.1 1938253 R 585054 CDS YP_002383028.1 218549237 7119914 complement(1939077..1940015) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11237876, 10493123; Product type e : enzyme; 2-ketoacid reductase 1940015 ycdW 7119914 ycdW Escherichia fergusonii ATCC 35469 2-ketoacid reductase YP_002383028.1 1939077 R 585054 CDS YP_002383029.1 218549238 7120034 complement(1940790..1942307) 1 NC_011740.1 class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 1942307 lysU 7120034 lysU Escherichia fergusonii ATCC 35469 lysyl-tRNA synthetase YP_002383029.1 1940790 R 585054 CDS YP_002383030.1 218549239 7123829 complement(1942576..1944033) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter 1944033 yjdL 7123829 yjdL Escherichia fergusonii ATCC 35469 transporter YP_002383030.1 1942576 R 585054 CDS YP_002383031.1 218549240 7122005 complement(1944092..1946239) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92105022, 92210511, 1370290, 1556085, 4204273; Product type e : enzyme; lysine decarboxylase 1 1946239 cadA 7122005 cadA Escherichia fergusonii ATCC 35469 lysine decarboxylase 1 YP_002383031.1 1944092 R 585054 CDS YP_002383032.1 218549241 7121686 complement(1946319..1947653) 1 NC_011740.1 antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein; lysine/cadaverine antiporter 1947653 cadB 7121686 cadB Escherichia fergusonii ATCC 35469 lysine/cadaverine antiporter YP_002383032.1 1946319 R 585054 CDS YP_002383033.1 218549242 7121687 complement(1948017..1949546) 1 NC_011740.1 regulates the cadBA operon; DNA-binding transcriptional activator CadC 1949546 cadC 7121687 cadC Escherichia fergusonii ATCC 35469 DNA-binding transcriptional activator CadC YP_002383033.1 1948017 R 585054 CDS YP_002383034.1 218549243 7123908 complement(1949886..1951277) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16530465, 17322315; Product type pe : enzyme; diguanylate cyclase, GGDEF protein 1951277 ycdT 7123908 ycdT Escherichia fergusonii ATCC 35469 diguanylate cyclase, GGDEF protein YP_002383034.1 1949886 R 585054 CDS YP_002383035.1 218549244 7123612 1951826..1954249 1 NC_011740.1 outer membrane protein essential for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PGA); adhesin required for biofilm formation; PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface; member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia; outer membrane protein PgaA 1954249 pgaA 7123612 pgaA Escherichia fergusonii ATCC 35469 outer membrane protein PgaA YP_002383035.1 1951826 D 585054 CDS YP_002383036.1 218549245 7122586 1954258..1956276 1 NC_011740.1 in Yersinia this protein is involved in biofilm formation and hemin adsorption; related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1,6-N-acetyl-D-glucosamine (PGA) export; outer membrane N-deacetylase 1956276 pgaB 7122586 pgaB Escherichia fergusonii ATCC 35469 outer membrane N-deacetylase YP_002383036.1 1954258 D 585054 CDS YP_002383037.1 218549246 7124066 1956269..1957594 1 NC_011740.1 predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein; N-glycosyltransferase 1957594 pgaC 7124066 pgaC Escherichia fergusonii ATCC 35469 N-glycosyltransferase YP_002383037.1 1956269 D 585054 CDS YP_002383038.1 218549247 7124067 1957596..1958009 1 NC_011740.1 in Yersinia this gene is involved in biofilm formation and hemin adsorption; in Escherichia coli it is involved in PGA biosynthesis and export; PGA biosynthesis protein 1958009 pgaD 7124067 pgaD Escherichia fergusonii ATCC 35469 PGA biosynthesis protein YP_002383038.1 1957596 D 585054 CDS YP_002383039.1 218549248 7119912 complement(1958050..1958973) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8444794, 2160940; Product type pe : enzyme; hypothetical protein 1958973 phoH 7119912 phoH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383039.1 1958050 R 585054 CDS YP_002383040.1 218549249 7122600 complement(1959446..1960717) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 17627767, 16551627, 15375152; Product type t : transporter; iron transport heme-binding periplasmic protein 1960717 efeB 7122600 efeB Escherichia fergusonii ATCC 35469 iron transport heme-binding periplasmic protein YP_002383040.1 1959446 R 585054 CDS YP_002383041.1 218549250 7124132 complement(1960723..1961850) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 17627767, 10493123; Product type t : transporter; hypothetical protein 1961850 efeO 7124132 efeO Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383041.1 1960723 R 585054 CDS YP_002383042.1 218549251 7122938 complement(1961908..1962747) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; ferrous iron permease 1962747 efeU 7122938 efeU Escherichia fergusonii ATCC 35469 ferrous iron permease YP_002383042.1 1961908 R 585054 CDS YP_002383043.1 218549252 7122939 complement(1962958..1964466) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12923181, 88213396, 91227628, 93132799, 98359785, 1400239, 1567896, 3053649, 3053687, 3302614, 3325781, 8119910; Product type t : transporter; proline:sodium symporter 1964466 putP 7122939 putP Escherichia fergusonii ATCC 35469 proline:sodium symporter YP_002383043.1 1962958 R 585054 CDS YP_002383044.1 218549253 7122331 1964889..1968851 1 NC_011740.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; multifunctional functional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 1968851 putA 7122331 putA Escherichia fergusonii ATCC 35469 multifunctional functional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase YP_002383044.1 1964889 D 585054 CDS YP_002383045.1 218549254 7122330 complement(1968944..1969885) 1 NC_011740.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 1969885 msbB 7122330 msbB Escherichia fergusonii ATCC 35469 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase YP_002383045.1 1968944 R 585054 CDS YP_002383046.1 218549255 7120971 complement(1969962..1970867) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1406277; Product type r : regulator; VirG localization protein VirK 1970867 virK 7120971 virK Escherichia fergusonii ATCC 35469 VirG localization protein VirK YP_002383046.1 1969962 R 585054 CDS YP_002383047.1 218549256 7122657 complement(1970913..1972001) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; glycosyl transferase family protein 1972001 7122657 EFER_1916 Escherichia fergusonii ATCC 35469 glycosyl transferase family protein YP_002383047.1 1970913 R 585054 CDS YP_002383048.1 218549257 7122747 complement(1972054..1972197) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1972197 7122747 EFER_1917 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383048.1 1972054 R 585054 CDS YP_002383049.1 218549258 7122748 complement(1972226..1973044) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; carbohydrate transport protein 1973044 shf 7122748 shf Escherichia fergusonii ATCC 35469 carbohydrate transport protein YP_002383049.1 1972226 R 585054 CDS YP_002383050.1 218549259 7121781 complement(1973225..1974493) 1 NC_011740.1 binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuC 1974493 umuC 7121781 umuC Escherichia fergusonii ATCC 35469 DNA polymerase V subunit UmuC YP_002383050.1 1973225 R 585054 CDS YP_002383051.1 218549260 7122637 complement(1974493..1974912) 1 NC_011740.1 binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuD 1974912 umuD 7122637 umuD Escherichia fergusonii ATCC 35469 DNA polymerase V subunit UmuD YP_002383051.1 1974493 R 585054 CDS YP_002383052.1 218549261 7122638 complement(1975170..1975484) 1 NC_011740.1 forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE 1975484 fliE 7122638 fliE Escherichia fergusonii ATCC 35469 flagellar hook-basal body protein FliE YP_002383052.1 1975170 R 585054 CDS YP_002383053.1 218549262 7122984 complement(1975529..1975678) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1975678 7122984 EFER_1922 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383053.1 1975529 R 585054 CDS YP_002383054.1 218549263 7122749 1975699..1977357 1 NC_011740.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 1977357 fliF 7122749 fliF Escherichia fergusonii ATCC 35469 flagellar MS-ring protein YP_002383054.1 1975699 D 585054 CDS YP_002383055.1 218549264 7122985 1977350..1978345 1 NC_011740.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 1978345 fliG 7122985 fliG Escherichia fergusonii ATCC 35469 flagellar motor switch protein G YP_002383055.1 1977350 D 585054 CDS YP_002383056.1 218549265 7123565 1978338..1979024 1 NC_011740.1 binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 1979024 fliH 7123565 fliH Escherichia fergusonii ATCC 35469 flagellar assembly protein H YP_002383056.1 1978338 D 585054 CDS YP_002383057.1 218549266 7123566 1979021..1980394 1 NC_011740.1 involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 1980394 fliI 7123566 fliI Escherichia fergusonii ATCC 35469 flagellum-specific ATP synthase YP_002383057.1 1979021 D 585054 CDS YP_002383058.1 218549267 7122986 1980416..1980859 1 NC_011740.1 rod/hook and filament chaperone; flagellar biosynthesis chaperone 1980859 fliJ 7122986 fliJ Escherichia fergusonii ATCC 35469 flagellar biosynthesis chaperone YP_002383058.1 1980416 D 585054 CDS YP_002383059.1 218549268 7122987 1980856..1982004 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8631687; Product type s : structure; flagellar hook-length control protein 1982004 fliK 7122987 fliK Escherichia fergusonii ATCC 35469 flagellar hook-length control protein YP_002383059.1 1980856 D 585054 CDS YP_002383060.1 218549269 7122988 1982109..1982567 1 NC_011740.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body-associated protein FliL 1982567 fliL 7122988 fliL Escherichia fergusonii ATCC 35469 flagellar basal body-associated protein FliL YP_002383060.1 1982109 D 585054 CDS YP_002383061.1 218549270 7122989 1982572..1983576 1 NC_011740.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 1983576 fliM 7122989 fliM Escherichia fergusonii ATCC 35469 flagellar motor switch protein FliM YP_002383061.1 1982572 D 585054 CDS YP_002383062.1 218549271 7122990 1983573..1983986 1 NC_011740.1 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliN 1983986 fliN 7122990 fliN Escherichia fergusonii ATCC 35469 flagellar motor switch protein FliN YP_002383062.1 1983573 D 585054 CDS YP_002383063.1 218549272 7122991 1983988..1984350 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8282695; Product type s : structure; Flagellar protein fliO 1984350 fliO 7122991 fliO Escherichia fergusonii ATCC 35469 Flagellar protein fliO YP_002383063.1 1983988 D 585054 CDS YP_002383064.1 218549273 7122992 1984350..1985087 1 NC_011740.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 1985087 fliP 7122992 fliP Escherichia fergusonii ATCC 35469 flagellar biosynthesis protein FliP YP_002383064.1 1984350 D 585054 CDS YP_002383065.1 218549274 7124139 1985096..1985365 1 NC_011740.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ 1985365 fliQ 7124139 fliQ Escherichia fergusonii ATCC 35469 flagellar biosynthesis protein FliQ YP_002383065.1 1985096 D 585054 CDS YP_002383066.1 218549275 7122993 1985358..1986161 1 NC_011740.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 1986161 fliR 7122993 fliR Escherichia fergusonii ATCC 35469 flagellar biosynthesis protein FliR YP_002383066.1 1985358 D 585054 CDS YP_002383067.1 218549276 7122994 1986438..1987061 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14514676, 14766922, 20167175, 90130299, 91154130, 92048476, 9882673, 7534408; Product type r : regulator; DNA-binding transcriptional activator 1987061 rcsA 7122994 rcsA Escherichia fergusonii ATCC 35469 DNA-binding transcriptional activator YP_002383067.1 1986438 D 585054 CDS YP_002383068.1 218549277 7124027 complement(1987109..1987297) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 96324407, 7534408; hypothetical protein 1987297 dsrB 7124027 dsrB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383068.1 1987109 R 585054 CDS YP_002383069.1 218549278 7122927 1987449..1987676 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1987676 yodD 7122927 yodD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383069.1 1987449 D 585054 CDS YP_002383070.1 218549279 7122925 1987844..1988791 1 NC_011740.1 catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate; mannosyl-3-phosphoglycerate phosphatase 1988791 7122925 EFER_1939 Escherichia fergusonii ATCC 35469 mannosyl-3-phosphoglycerate phosphatase YP_002383070.1 1987844 D 585054 CDS YP_002383071.1 218549280 7122750 complement(1988764..1990476) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; diguanylate cyclase; GGDEF domain; PLP-dependent transferase 1990476 7122750 EFER_1940 Escherichia fergusonii ATCC 35469 diguanylate cyclase; GGDEF domain; PLP-dependent transferase YP_002383071.1 1988764 R 585054 CDS YP_002383072.1 218549281 7122751 complement(1990596..1990835) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1990835 7122751 EFER_1941 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383072.1 1990596 R 585054 CDS YP_002383073.1 218549282 7122752 complement(1990853..1991764) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1991764 yedI 7122752 yedI Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383073.1 1990853 R 585054 CDS YP_002383074.1 218549283 7121540 1991941..1992861 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1992861 yedA 7121540 yedA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383074.1 1991941 D 585054 CDS YP_002383075.1 218549284 7121536 complement(1992853..1993326) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90330522, 92049708, 94049122, 10360178, 10612397, 10871403, 2527357; Product type e : enzyme; DNA mismatch endonuclease of very short patch repair 1993326 vsr 7121536 vsr Escherichia fergusonii ATCC 35469 DNA mismatch endonuclease of very short patch repair YP_002383075.1 1992853 R 585054 CDS YP_002383076.1 218549285 7124079 complement(1993345..1994034) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1994034 7124079 EFER_1945 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383076.1 1993345 R 585054 CDS YP_002383077.1 218549286 7123527 complement(1994087..1994374) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; permease 1994374 7123527 EFER_1947 Escherichia fergusonii ATCC 35469 permease YP_002383077.1 1994087 R 585054 CDS YP_002383078.1 218549287 7122753 1995018..1996073 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type m : membrane component; outer membrane protein N 1996073 7122753 EFER_1948 Escherichia fergusonii ATCC 35469 outer membrane protein N YP_002383078.1 1995018 D 585054 CDS YP_002383079.1 218549288 7122754 1996644..1997747 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 3017988, 8057841; Product type m : membrane component; outer membrane porin; DLP12 prophage 1997747 nmpC 7122754 nmpC Escherichia fergusonii ATCC 35469 outer membrane porin; DLP12 prophage YP_002383079.1 1996644 D 585054 CDS YP_002383080.1 218549289 7119653 1998187..1999662 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; Trk system potassium uptake protein 1999662 trkG 7119653 trkG Escherichia fergusonii ATCC 35469 Trk system potassium uptake protein YP_002383080.1 1998187 D 585054 CDS YP_002383081.1 218549290 7123435 1999771..2000622 1 NC_011740.1 Hsp31 stabilizes early unfolding protein intermediates under severe heat stress; chaperone protein HchA 2000622 hchA 7123435 hchA Escherichia fergusonii ATCC 35469 chaperone protein HchA YP_002383081.1 1999771 D 585054 CDS YP_002383082.1 218549291 7123098 2001152..2001949 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2001949 yeeI 7123098 yeeI Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383082.1 2001152 D 585054 CDS YP_002383083.1 218549292 7123632 complement(2002164..2003114) 1 NC_011740.1 LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB; transcriptional regulator Cbl 2003114 cbl 7123632 cbl Escherichia fergusonii ATCC 35469 transcriptional regulator Cbl YP_002383083.1 2002164 R 585054 CDS YP_002383084.1 218549293 7120861 complement(2003216..2004133) 1 NC_011740.1 Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation; nitrogen assimilation transcriptional regulator 2004133 nac 7120861 nac Escherichia fergusonii ATCC 35469 nitrogen assimilation transcriptional regulator YP_002383084.1 2003216 R 585054 CDS YP_002383085.1 218549294 7123633 2004648..2004971 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; phage integrase 2004971 7123633 EFER_1956 Escherichia fergusonii ATCC 35469 phage integrase YP_002383085.1 2004648 D 585054 CDS YP_002383086.1 218549295 7123528 complement(2005212..2005358) 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 2005358 7123528 EFER_1957 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383086.1 2005212 R 585054 CDS YP_002383087.1 218549296 7122755 complement(2005536..2005895) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2005895 7122755 EFER_1958 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383087.1 2005536 R 585054 CDS YP_002383088.1 218549297 7122756 complement(2005907..2006371) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; hypothetical protein 2006371 7122756 EFER_1959 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383088.1 2005907 R 585054 CDS YP_002383089.1 218549298 7123529 complement(2007155..2007604) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2007604 7123529 EFER_1960 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383089.1 2007155 R 585054 CDS YP_002383090.1 218549299 7122757 complement(2007604..2008275) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2008275 7122757 EFER_1961 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383090.1 2007604 R 585054 CDS YP_002383091.1 218549300 7122758 complement(2008475..2008954) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 16763151; hypothetical protein 2008954 7122758 EFER_1962 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383091.1 2008475 R 585054 CDS YP_002383092.1 218549301 7124097 complement(2008972..2010477) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2010477 7124097 EFER_1963 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383092.1 2008972 R 585054 CDS YP_002383093.1 218549302 7122759 complement(2010341..2013862) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type pe : enzyme; IcmF-like protein 2013862 7122759 EFER_1964 Escherichia fergusonii ATCC 35469 IcmF-like protein YP_002383093.1 2010341 R 585054 CDS YP_002383094.1 218549303 7123530 complement(2013881..2015314) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2015314 7123530 EFER_1965 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383094.1 2013881 R 585054 CDS YP_002383095.1 218549304 7122760 complement(2015317..2016060) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2016060 7122760 EFER_1966 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383095.1 2015317 R 585054 CDS YP_002383096.1 218549305 7122761 complement(2016057..2018783) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; ATP-dependent Clp proteinase ATP-binding subunit 2018783 7122761 EFER_1967 Escherichia fergusonii ATCC 35469 ATP-dependent Clp proteinase ATP-binding subunit YP_002383096.1 2016057 R 585054 CDS YP_002383097.1 218549306 7123531 complement(2018792..2019601) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; membrane protein Aec26 2019601 7123531 EFER_1968 Escherichia fergusonii ATCC 35469 membrane protein Aec26 YP_002383097.1 2018792 R 585054 CDS YP_002383098.1 218549307 7122762 complement(2019594..2021051) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2021051 7122762 EFER_1969 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383098.1 2019594 R 585054 CDS YP_002383099.1 218549308 7122763 complement(2020952..2021485) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2021485 7122763 EFER_1970 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383099.1 2020952 R 585054 CDS YP_002383100.1 218549309 7123532 complement(2021482..2022762) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2022762 7123532 EFER_1971 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383100.1 2021482 R 585054 CDS YP_002383101.1 218549310 7122764 complement(2022786..2023823) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2023823 7122764 EFER_1972 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383101.1 2022786 R 585054 CDS YP_002383102.1 218549311 7122765 complement(2023787..2025619) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2025619 7122765 EFER_1973 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383102.1 2023787 R 585054 CDS YP_002383103.1 218549312 7124098 complement(2025625..2026062) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2026062 7124098 EFER_1974 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383103.1 2025625 R 585054 CDS YP_002383104.1 218549313 7122766 complement(2026065..2027546) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2027546 7122766 EFER_1975 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383104.1 2026065 R 585054 CDS YP_002383105.1 218549314 7122767 complement(2027561..2028160) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2028160 7122767 EFER_1976 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383105.1 2027561 R 585054 CDS YP_002383106.1 218549315 7124099 2028690..2029271 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2029271 7124099 EFER_1977 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383106.1 2028690 D 585054 CDS YP_002383107.1 218549316 7122768 2029481..2031427 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2031427 7122768 EFER_1978 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383107.1 2029481 D 585054 CDS YP_002383108.1 218549317 7122769 2031449..2031868 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2031868 7122769 EFER_1979 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383108.1 2031449 D 585054 CDS YP_002383109.1 218549318 7123533 2031895..2036526 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2036526 7123533 EFER_1980 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383109.1 2031895 D 585054 CDS YP_002383110.1 218549319 7122770 2036533..2036805 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2036805 7122770 EFER_1981 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383110.1 2036533 D 585054 CDS YP_002383111.1 218549320 7122671 complement(2037984..2039438) 1 NC_011740.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase 2039438 amn 7122671 amn Escherichia fergusonii ATCC 35469 AMP nucleosidase YP_002383111.1 2037984 R 585054 CDS YP_002383112.1 218549321 7122302 complement(2039566..2040870) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 5332864, 9524262; Product type t : transporter; shikimate transporter 2040870 shiA 7122302 shiA Escherichia fergusonii ATCC 35469 shikimate transporter YP_002383112.1 2039566 R 585054 CDS YP_002383113.1 218549322 7120078 complement(2041421..2042857) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16042411; Product type pt : transporter; hypothetical protein 2042857 yeeO 7120078 yeeO Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383113.1 2041421 R 585054 CDS YP_002383114.1 218549323 7120035 2043439..2044017 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2044017 7120035 EFER_1986 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383114.1 2043439 D 585054 CDS YP_002383115.1 218549324 7124100 2044040..2044858 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2044858 7124100 EFER_1987 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383115.1 2044040 D 585054 CDS YP_002383116.1 218549325 7122772 2044858..2045376 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2045376 7122772 EFER_1988 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383116.1 2044858 D 585054 CDS YP_002383117.1 218549326 7122773 2045845..2046174 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10768928, 9370271, 9573168, 11964144, 4295288; Product type ps : structure; propanediol utilization protein PduJ/pduA 2046174 7122773 EFER_1989 Escherichia fergusonii ATCC 35469 propanediol utilization protein PduJ/pduA YP_002383117.1 2045845 D 585054 CDS YP_002383118.1 218549327 7124101 2046192..2046476 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12007656, 8071226, 9352910, 10498708; Product type ps : structure; propanediol utilization protein pduA/pduJ 2046476 7124101 EFER_1990 Escherichia fergusonii ATCC 35469 propanediol utilization protein pduA/pduJ YP_002383118.1 2046192 D 585054 CDS YP_002383119.1 218549328 7122774 2046491..2046769 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8071226, 9352910, 10498708; Product type ps : structure; propanediol utilization protein: polyhedral bodies pduJ or pduA 2046769 7122774 EFER_1991 Escherichia fergusonii ATCC 35469 propanediol utilization protein: polyhedral bodies pduJ or pduA YP_002383119.1 2046491 D 585054 CDS YP_002383120.1 218549329 7123454 2048436..2048693 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; ethanolamine utilization protein EutN/carboxysome structural protein Ccml 2048693 7123454 EFER_1993 Escherichia fergusonii ATCC 35469 ethanolamine utilization protein EutN/carboxysome structural protein Ccml YP_002383120.1 2048436 D 585054 CDS YP_002383121.1 218549330 7123455 2049854..2053276 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; Formate C-acetyltransferase 2053276 7123455 EFER_1995 Escherichia fergusonii ATCC 35469 Formate C-acetyltransferase YP_002383121.1 2049854 D 585054 CDS YP_002383122.1 218549331 7122776 2053328..2054275 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; pyruvate formate-lyase activating enzyme 2054275 7122776 EFER_1996 Escherichia fergusonii ATCC 35469 pyruvate formate-lyase activating enzyme YP_002383122.1 2053328 D 585054 CDS YP_002383123.1 218549332 7122777 2054287..2054769 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; microcompartments protein 2054769 7122777 EFER_1997 Escherichia fergusonii ATCC 35469 microcompartments protein YP_002383123.1 2054287 D 585054 CDS YP_002383124.1 218549333 7122778 2054766..2055386 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2055386 7122778 EFER_1998 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383124.1 2054766 D 585054 CDS YP_002383125.1 218549334 7122779 2055398..2056063 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2056063 7122779 EFER_1999 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383125.1 2055398 D 585054 CDS YP_002383126.1 218549335 7122780 2056096..2056497 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; membrane transport protein 2056497 7122780 EFER_2000 Escherichia fergusonii ATCC 35469 membrane transport protein YP_002383126.1 2056096 D 585054 CDS YP_002383127.1 218549336 7122781 2056507..2056842 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; multidrug resistance protein 2056842 7122781 EFER_2001 Escherichia fergusonii ATCC 35469 multidrug resistance protein YP_002383127.1 2056507 D 585054 CDS YP_002383128.1 218549337 7122782 complement(2056909..2057835) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9298646; hypothetical protein 2057835 erfK 7122782 erfK Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383128.1 2056909 R 585054 CDS YP_002383129.1 218549338 7122962 complement(2058050..2058535) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2058535 7122962 EFER_2003 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383129.1 2058050 R 585054 CDS YP_002383130.1 218549339 7122783 complement(2059035..2059952) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 8071226; Product type f : factor; propanediol utilization: transcriptional regulation 2059952 pocR 7122783 pocR Escherichia fergusonii ATCC 35469 propanediol utilization: transcriptional regulation YP_002383130.1 2059035 R 585054 CDS YP_002383131.1 218549340 7120096 complement(2060147..2060941) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 9352910; Product type m : membrane component; propanediol diffusion facilitator 2060941 pduF 7120096 pduF Escherichia fergusonii ATCC 35469 propanediol diffusion facilitator YP_002383131.1 2060147 R 585054 CDS YP_002383132.1 218549341 7122570 2061443..2061727 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10498708; Product type ps : structure; propanediol utilization protein, polyhedral bodies (pduA-like) 2061727 7122570 EFER_2008 Escherichia fergusonii ATCC 35469 propanediol utilization protein, polyhedral bodies (pduA-like) YP_002383132.1 2061443 D 585054 CDS YP_002383133.1 218549342 7122784 2061724..2062533 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; propanediol utilization protein: polyhedral bodies pduB 2062533 7122784 EFER_2009 Escherichia fergusonii ATCC 35469 propanediol utilization protein: polyhedral bodies pduB YP_002383133.1 2061724 D 585054 CDS YP_002383134.1 218549343 7122785 2062552..2064216 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9352910; Product type e : enzyme; glycerol dehydratase large subunit 2064216 pduC 7122785 pduC Escherichia fergusonii ATCC 35469 glycerol dehydratase large subunit YP_002383134.1 2062552 D 585054 CDS YP_002383135.1 218549344 7123501 2064227..2064889 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7706251, 12788698; Product type e : enzyme; propanediol utilization: diol dehydratase, medium subunit 2064889 PduD 7123501 PduD Escherichia fergusonii ATCC 35469 propanediol utilization: diol dehydratase, medium subunit YP_002383135.1 2064227 D 585054 CDS YP_002383136.1 218549345 7122568 2064904..2065428 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9352910; Product type e : enzyme; propanediol utilization diol dehydratase small subunit 2065428 pduE 7122568 pduE Escherichia fergusonii ATCC 35469 propanediol utilization diol dehydratase small subunit YP_002383136.1 2064904 D 585054 CDS YP_002383137.1 218549346 7122569 2065439..2067271 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10498708, 12788698; Product type pe : enzyme; propanediol utilization: diol dehydratase reactivation PduG 2067271 7122569 EFER_2013 Escherichia fergusonii ATCC 35469 propanediol utilization: diol dehydratase reactivation PduG YP_002383137.1 2065439 D 585054 CDS YP_002383138.1 218549347 7122786 2067033..2067611 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12788698, 10498708; Product type pe : enzyme; propanediol utilization: diol dehydratase reactivation PduH 2067611 7122786 EFER_2014 Escherichia fergusonii ATCC 35469 propanediol utilization: diol dehydratase reactivation PduH YP_002383138.1 2067033 D 585054 CDS YP_002383139.1 218549348 7122787 2067932..2068366 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; propanediol utilization protein: polyhedral bodies PduK 2068366 7122787 EFER_2016 Escherichia fergusonii ATCC 35469 propanediol utilization protein: polyhedral bodies PduK YP_002383139.1 2067932 D 585054 CDS YP_002383140.1 218549349 7122788 2068366..2068998 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10498708; hypothetical protein 2068998 7122788 EFER_2017 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383140.1 2068366 D 585054 CDS YP_002383141.1 218549350 7123535 2068971..2069486 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2069486 7123535 EFER_2018 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383141.1 2068971 D 585054 CDS YP_002383142.1 218549351 7122789 2069490..2069765 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10498708; Product type ps : structure; propanediol utilization: polyhedral bodies pduN 2069765 7122789 EFER_2019 Escherichia fergusonii ATCC 35469 propanediol utilization: polyhedral bodies pduN YP_002383142.1 2069490 D 585054 CDS YP_002383143.1 218549352 7122790 2069776..2070783 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; propanediol utilization protein: B12 related pduO, Bifunctional ATP:cob(I)alamin adenosyltransferase/GlcG domain 2070783 7122790 EFER_2020 Escherichia fergusonii ATCC 35469 propanediol utilization protein: B12 related pduO, Bifunctional ATP:cob(I)alamin adenosyltransferase/GlcG domain YP_002383143.1 2069776 D 585054 CDS YP_002383144.1 218549353 7124103 2070780..2072162 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10498708; Product type pe : enzyme; CoA-dependent proprionaldehyde dehydrogenase pduP 2072162 7124103 EFER_2021 Escherichia fergusonii ATCC 35469 CoA-dependent proprionaldehyde dehydrogenase pduP YP_002383144.1 2070780 D 585054 CDS YP_002383145.1 218549354 7121195 2072173..2073285 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10498708; Product type pe : enzyme; propanediol utilization propanol dehydrogenase pduQ 2073285 7121195 EFER_2022 Escherichia fergusonii ATCC 35469 propanediol utilization propanol dehydrogenase pduQ YP_002383145.1 2072173 D 585054 CDS YP_002383146.1 218549355 7121261 2073282..2074622 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; propanediol utilization protein: ferredoxin pduS 2074622 7121261 EFER_2023 Escherichia fergusonii ATCC 35469 propanediol utilization protein: ferredoxin pduS YP_002383146.1 2073282 D 585054 CDS YP_002383147.1 218549356 7121262 2074625..2075179 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; propanediol utilization: polyhedral bodies pduT 2075179 7121262 EFER_2024 Escherichia fergusonii ATCC 35469 propanediol utilization: polyhedral bodies pduT YP_002383147.1 2074625 D 585054 CDS YP_002383148.1 218549357 7123291 2075155..2075529 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10498708; Product type ps : structure; propanediol utilization protein: polyhedral bodies pduU 2075529 7123291 EFER_2025 Escherichia fergusonii ATCC 35469 propanediol utilization protein: polyhedral bodies pduU YP_002383148.1 2075155 D 585054 CDS YP_002383149.1 218549358 7123836 2075531..2075980 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10498708; hypothetical protein 2075980 7123836 EFER_2026 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383149.1 2075531 D 585054 CDS YP_002383150.1 218549359 7121263 2075970..2077184 1 NC_011740.1 involved in coenzyme B(12)-dependent 1, 2-propanediol degradation; important for the synthesis of propionyl coenzyme A during growth on 1,2-propanediol; propionate kinase 2077184 7121263 EFER_2027 Escherichia fergusonii ATCC 35469 propionate kinase YP_002383150.1 2075970 D 585054 CDS YP_002383151.1 218549360 7121264 complement(2077294..2077629) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2077629 yeeX 7121264 yeeX Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383151.1 2077294 R 585054 CDS YP_002383152.1 218549361 7121549 complement(2077797..2078864) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 15919996; Inner membrane protein yeeA 2078864 yeeA 7121549 yeeA Escherichia fergusonii ATCC 35469 Inner membrane protein yeeA YP_002383152.1 2077797 R 585054 CDS YP_002383153.1 218549362 7121545 complement(2078962..2079429) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8709849, 9442027; Product type pe : enzyme; DNA gyrase inhibitor 2079429 sbmC 7121545 sbmC Escherichia fergusonii ATCC 35469 DNA gyrase inhibitor YP_002383153.1 2078962 R 585054 CDS YP_002383154.1 218549363 7121752 2080141..2080344 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2080344 7121752 EFER_2031 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383154.1 2080141 D 585054 CDS YP_002383155.1 218549364 7123837 2080287..2082317 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; acyltransferase 2082317 7123837 EFER_2032 Escherichia fergusonii ATCC 35469 acyltransferase YP_002383155.1 2080287 D 585054 CDS YP_002383156.1 218549365 7121265 complement(2082356..2084794) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; head-binding domain of phage tailspike protein 2084794 7121265 EFER_2033 Escherichia fergusonii ATCC 35469 head-binding domain of phage tailspike protein YP_002383156.1 2082356 R 585054 CDS YP_002383157.1 218549366 7123292 complement(2084927..2086771) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; DNA transfer protein from phage 2086771 7123292 EFER_2034 Escherichia fergusonii ATCC 35469 DNA transfer protein from phage YP_002383157.1 2084927 R 585054 CDS YP_002383158.1 218549367 7121266 complement(2086768..2088180) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; DNA transfer protein gp20 2088180 7121266 EFER_2035 Escherichia fergusonii ATCC 35469 DNA transfer protein gp20 YP_002383158.1 2086768 R 585054 CDS YP_002383159.1 218549368 7121267 complement(2088193..2088846) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; DNA transfer protein gp7 from phage origin 2088846 7121267 EFER_2036 Escherichia fergusonii ATCC 35469 DNA transfer protein gp7 from phage origin YP_002383159.1 2088193 R 585054 CDS YP_002383160.1 218549369 7121268 complement(2088821..2089303) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2089303 7121268 EFER_2037 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383160.1 2088821 R 585054 CDS YP_002383161.1 218549370 7121269 complement(2089300..2090148) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Packaged DNA stabilization protein gp26 2090148 GP 7121269 GP Escherichia fergusonii ATCC 35469 Packaged DNA stabilization protein gp26 YP_002383161.1 2089300 R 585054 CDS YP_002383162.1 218549371 7120603 complement(2090148..2091566) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Packaged DNA stabilization protein from phage 2091566 7120603 EFER_2039 Escherichia fergusonii ATCC 35469 Packaged DNA stabilization protein from phage YP_002383162.1 2090148 R 585054 CDS YP_002383163.1 218549372 7123293 complement(2091567..2092178) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; DNA stabilization protein GP4 2092178 GP 7123293 GP Escherichia fergusonii ATCC 35469 DNA stabilization protein GP4 YP_002383163.1 2091567 R 585054 CDS YP_002383164.1 218549373 7123725 complement(2092045..2092365) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2092365 7123725 EFER_2041 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383164.1 2092045 R 585054 CDS YP_002383165.1 218549374 7121270 complement(2092362..2093657) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Coat protein 2093657 GP 7121270 GP Escherichia fergusonii ATCC 35469 Coat protein YP_002383165.1 2092362 R 585054 CDS YP_002383166.1 218549375 7120604 complement(2093657..2094568) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Scaffolding protein (protein gp8) 2094568 GP 7120604 GP Escherichia fergusonii ATCC 35469 Scaffolding protein (protein gp8) YP_002383166.1 2093657 R 585054 CDS YP_002383167.1 218549376 7120605 complement(2094582..2096747) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Portal protein (protein gp1) 2096747 GP 7120605 GP Escherichia fergusonii ATCC 35469 Portal protein (protein gp1) YP_002383167.1 2094582 R 585054 CDS YP_002383168.1 218549377 7123726 complement(2096748..2098247) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; DNA packaging protein gp2 (Terminase large subunit) 2098247 GP 7123726 GP Escherichia fergusonii ATCC 35469 DNA packaging protein gp2 (Terminase large subunit) YP_002383168.1 2096748 R 585054 CDS YP_002383169.1 218549378 7120606 complement(2098225..2098719) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; DNA packaging protein gp3 (Terminase small subunit) 2098719 GP 7120606 GP Escherichia fergusonii ATCC 35469 DNA packaging protein gp3 (Terminase small subunit) YP_002383169.1 2098225 R 585054 CDS YP_002383170.1 218549379 7120607 complement(2098737..2098916) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2098916 7120607 EFER_2047 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383170.1 2098737 R 585054 CDS YP_002383171.1 218549380 7123294 complement(2098918..2099160) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2099160 7123294 EFER_2048 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383171.1 2098918 R 585054 CDS YP_002383172.1 218549381 7121271 complement(2099513..2100274) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2100274 7121271 EFER_2049 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383172.1 2099513 R 585054 CDS YP_002383173.1 218549382 7121272 complement(2100234..2100386) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; bacteriophage protein (Gene 65) 2100386 7121272 EFER_2050 Escherichia fergusonii ATCC 35469 bacteriophage protein (Gene 65) YP_002383173.1 2100234 R 585054 CDS YP_002383174.1 218549383 7123295 complement(2100374..2100853) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; lysis protein Rz 2100853 Rz 7123295 Rz Escherichia fergusonii ATCC 35469 lysis protein Rz YP_002383174.1 2100374 R 585054 CDS YP_002383175.1 218549384 7121187 complement(2100838..2101335) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3017988; Product type pe : enzyme; lysozyme; DLP12 prophage 2101335 ybcS 7121187 ybcS Escherichia fergusonii ATCC 35469 lysozyme; DLP12 prophage YP_002383175.1 2100838 R 585054 CDS YP_002383176.1 218549385 7123804 complement(2101313..2101516) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2101516 7123804 EFER_2053 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383176.1 2101313 R 585054 CDS YP_002383177.1 218549386 7123838 complement(2102187..2102810) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Antitermination protein Q 2102810 7123838 EFER_2054 Escherichia fergusonii ATCC 35469 Antitermination protein Q YP_002383177.1 2102187 R 585054 CDS YP_002383178.1 218549387 7121273 complement(2102807..2103547) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Serine/threonine-protein phosphatase 2103547 pph 7121273 pph Escherichia fergusonii ATCC 35469 Serine/threonine-protein phosphatase YP_002383178.1 2102807 R 585054 CDS YP_002383179.1 218549388 7120110 complement(2103450..2103656) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2103656 7120110 EFER_2056 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383179.1 2103450 R 585054 CDS YP_002383180.1 218549389 7121274 complement(2103653..2104264) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; protein ninG from prophage 2104264 ninG 7121274 ninG Escherichia fergusonii ATCC 35469 protein ninG from prophage YP_002383180.1 2103653 R 585054 CDS YP_002383181.1 218549390 7120694 complement(2104257..2104649) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2104649 7120694 EFER_2059 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383181.1 2104257 R 585054 CDS YP_002383182.1 218549391 7123839 complement(2104639..2104818) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2104818 ninF 7123839 ninF Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383182.1 2104639 R 585054 CDS YP_002383183.1 218549392 7123204 complement(2104818..2105237) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2105237 7123204 EFER_2061 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383183.1 2104818 R 585054 CDS YP_002383184.1 218549393 7121275 complement(2105371..2105787) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; ninB protein 2105787 7121275 EFER_2062 Escherichia fergusonii ATCC 35469 ninB protein YP_002383184.1 2105371 R 585054 CDS YP_002383185.1 218549394 7123840 complement(2105784..2106080) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2106080 7123840 EFER_2063 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383185.1 2105784 R 585054 CDS YP_002383186.1 218549395 7121276 complement(2106058..2106279) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2106279 7121276 EFER_2064 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383186.1 2106058 R 585054 CDS YP_002383187.1 218549396 7121277 2106581..2106727 1 NC_011740.1 Evidence 6 : Doubtful CDS; Product type h : extrachromosomal origin; hypothetical protein 2106727 7121277 EFER_2066 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383187.1 2106581 D 585054 CDS YP_002383188.1 218549397 7121278 complement(2106745..2108121) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; replicative DNA helicase 2108121 7121278 EFER_2067 Escherichia fergusonii ATCC 35469 replicative DNA helicase YP_002383188.1 2106745 R 585054 CDS YP_002383189.1 218549398 7123841 complement(2108118..2109065) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2109065 7123841 EFER_2068 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383189.1 2108118 R 585054 CDS YP_002383190.1 218549399 7121279 complement(2109068..2109505) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2109505 7121279 EFER_2069 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383190.1 2109068 R 585054 CDS YP_002383191.1 218549400 7123033 complement(2109363..2109659) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 375198; Product type h : extrachromosomal origin; Regulatory protein CII from phage origin 2109659 7123033 EFER_2070 Escherichia fergusonii ATCC 35469 Regulatory protein CII from phage origin YP_002383191.1 2109363 R 585054 CDS YP_002383192.1 218549401 7121281 complement(2109766..2110026) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; regulatory protein from bacteriophage origin 2110026 cro 7121281 cro Escherichia fergusonii ATCC 35469 regulatory protein from bacteriophage origin YP_002383192.1 2109766 R 585054 CDS YP_002383193.1 218549402 7123536 2110072..2110779 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; repressor protein of bacteriophage origin 2110779 cI 7123536 cI Escherichia fergusonii ATCC 35469 repressor protein of bacteriophage origin YP_002383193.1 2110072 D 585054 CDS YP_002383194.1 218549403 7120892 2110886..2111263 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 2111263 7120892 EFER_2073 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383194.1 2110886 D 585054 CDS YP_002383195.1 218549404 7121282 2111238..2111723 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 2111723 7121282 EFER_2074 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383195.1 2111238 D 585054 CDS YP_002383196.1 218549405 7123296 2112100..2112525 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2112525 7123296 EFER_2075 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383196.1 2112100 D 585054 CDS YP_002383197.1 218549406 7121283 complement(2112547..2112864) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 2112864 7121283 EFER_2076 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383197.1 2112547 R 585054 CDS YP_002383198.1 218549407 7121284 2112796..2112996 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Restriction inhibitor protein ral 2112996 7121284 EFER_2077 Escherichia fergusonii ATCC 35469 Restriction inhibitor protein ral YP_002383198.1 2112796 D 585054 CDS YP_002383199.1 218549408 7121285 2113118..2114137 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2114137 7121285 EFER_2078 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383199.1 2113118 D 585054 CDS YP_002383200.1 218549409 7121286 2114277..2114429 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; protein kil 2114429 kil 7121286 kil Escherichia fergusonii ATCC 35469 protein kil YP_002383200.1 2114277 D 585054 CDS YP_002383201.1 218549410 7120815 2114411..2114596 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2114596 7120815 EFER_2080 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383201.1 2114411 D 585054 CDS YP_002383202.1 218549411 7121287 2114505..2114675 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2114675 7121287 EFER_2081 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383202.1 2114505 D 585054 CDS YP_002383203.1 218549412 7123842 2114656..2115291 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; DNA single-strand annealing protein 2115291 erf 7123842 erf Escherichia fergusonii ATCC 35469 DNA single-strand annealing protein YP_002383203.1 2114656 D 585054 CDS YP_002383204.1 218549413 7122961 2115201..2115674 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2115674 7122961 EFER_2083 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383204.1 2115201 D 585054 CDS YP_002383205.1 218549414 7121288 2115677..2115994 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Anti-RecBCD protein 2 2115994 abc 7121288 abc Escherichia fergusonii ATCC 35469 Anti-RecBCD protein 2 YP_002383205.1 2115677 D 585054 CDS YP_002383206.1 218549415 7124007 2115852..2116295 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2116295 7124007 EFER_2085 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383206.1 2115852 D 585054 CDS YP_002383207.1 218549416 7121289 2116435..2116725 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2116725 7121289 EFER_2086 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383207.1 2116435 D 585054 CDS YP_002383208.1 218549417 7121290 2116712..2117266 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2117266 7121290 EFER_2087 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383208.1 2116712 D 585054 CDS YP_002383209.1 218549418 7121291 2117220..2117927 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2117927 7121291 EFER_2088 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383209.1 2117220 D 585054 CDS YP_002383210.1 218549419 7121292 2117879..2118199 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 2118199 7121292 EFER_2089 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383210.1 2117879 D 585054 CDS YP_002383211.1 218549420 7121293 2118196..2118483 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2118483 7121293 EFER_2090 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383211.1 2118196 D 585054 CDS YP_002383212.1 218549421 7121294 2118476..2118757 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2118757 7121294 EFER_2091 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383212.1 2118476 D 585054 CDS YP_002383213.1 218549422 7123843 2118852..2119019 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2119019 7123843 EFER_2092 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383213.1 2118852 D 585054 CDS YP_002383214.1 218549423 7121295 complement(2119222..2120418) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; integrase 2120418 int 7121295 int Escherichia fergusonii ATCC 35469 integrase YP_002383214.1 2119222 R 585054 CDS YP_002383215.1 218549424 7120750 2120582..2122006 1 NC_011740.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 2122006 sbcB 7120750 sbcB Escherichia fergusonii ATCC 35469 exonuclease I YP_002383215.1 2120582 D 585054 CDS YP_002383216.1 218549425 7121193 complement(2122049..2122276) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2122276 yeeD 7121193 yeeD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383216.1 2122049 R 585054 CDS YP_002383217.1 218549426 7123338 complement(2122290..2123348) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2123348 yeeE 7123338 yeeE Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383217.1 2122290 R 585054 CDS YP_002383218.1 218549427 7121546 complement(2123526..2124884) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; amino-acid/amine transporter 2124884 yeeF 7121546 yeeF Escherichia fergusonii ATCC 35469 amino-acid/amine transporter YP_002383218.1 2123526 R 585054 CDS YP_002383219.1 218549428 7123885 complement(2125150..2126079) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator 2126079 yeeY 7123885 yeeY Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YP_002383219.1 2125150 R 585054 CDS YP_002383220.1 218549429 7121550 complement(2126125..2126949) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; epimerase 2126949 yeeZ 7121550 yeeZ Escherichia fergusonii ATCC 35469 epimerase YP_002383220.1 2126125 R 585054 CDS YP_002383221.1 218549430 7121551 complement(2127032..2127286) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type f : factor; toxin of the YoeB-YefM toxin-antitoxin system 2127286 yoeB 7121551 yoeB Escherichia fergusonii ATCC 35469 toxin of the YoeB-YefM toxin-antitoxin system YP_002383221.1 2127032 R 585054 CDS YP_002383222.1 218549431 7123914 complement(2127283..2127534) 1 NC_011740.1 Antitoxin that counteracts the effect of the YoeB toxin; antitoxin YefM 2127534 yefM 7123914 yefM Escherichia fergusonii ATCC 35469 antitoxin YefM YP_002383222.1 2127283 R 585054 CDS YP_002383224.1 218549433 7123442 2128014..2128913 1 NC_011740.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 2128913 hisG 7123442 hisG Escherichia fergusonii ATCC 35469 ATP phosphoribosyltransferase YP_002383224.1 2128014 D 585054 CDS YP_002383225.1 218549434 7123998 2128919..2130223 1 NC_011740.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 2130223 hisD 7123998 hisD Escherichia fergusonii ATCC 35469 histidinol dehydrogenase YP_002383225.1 2128919 D 585054 CDS YP_002383226.1 218549435 7122196 2130220..2131290 1 NC_011740.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 2131290 hisC 7122196 hisC Escherichia fergusonii ATCC 35469 histidinol-phosphate aminotransferase YP_002383226.1 2130220 D 585054 CDS YP_002383227.1 218549436 7123997 2131290..2132357 1 NC_011740.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 2132357 hisB 7123997 hisB Escherichia fergusonii ATCC 35469 imidazole glycerol-phosphate dehydratase/histidinol phosphatase YP_002383227.1 2131290 D 585054 CDS YP_002383228.1 218549437 7122195 2132357..2132947 1 NC_011740.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2132947 hisH 7122195 hisH Escherichia fergusonii ATCC 35469 imidazole glycerol phosphate synthase subunit HisH YP_002383228.1 2132357 D 585054 CDS YP_002383229.1 218549438 7122198 2132947..2133684 1 NC_011740.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2133684 hisA 7122198 hisA Escherichia fergusonii ATCC 35469 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase YP_002383229.1 2132947 D 585054 CDS YP_002383230.1 218549439 7123441 2133666..2134442 1 NC_011740.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2134442 hisF 7123441 hisF Escherichia fergusonii ATCC 35469 imidazole glycerol phosphate synthase subunit HisF YP_002383230.1 2133666 D 585054 CDS YP_002383231.1 218549440 7122197 2134436..2135047 1 NC_011740.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase 2135047 hisI 7122197 hisI Escherichia fergusonii ATCC 35469 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase YP_002383231.1 2134436 D 585054 CDS YP_002383232.1 218549441 7122199 complement(2135141..2136121) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type m : membrane component; polysaccharide antigen chain regulator 2136121 7122199 EFER_2110 Escherichia fergusonii ATCC 35469 polysaccharide antigen chain regulator YP_002383232.1 2135141 R 585054 CDS YP_002383233.1 218549442 7121296 complement(2136353..2137546) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9150218, 96326333; Product type e : enzyme; UDP-glucose 6-dehydrogenase 2137546 ugd 7121296 ugd Escherichia fergusonii ATCC 35469 UDP-glucose 6-dehydrogenase YP_002383233.1 2136353 R 585054 CDS YP_002383234.1 218549443 7122624 complement(2137769..2139175) 1 NC_011740.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 2139175 gnd 7122624 gnd Escherichia fergusonii ATCC 35469 6-phosphogluconate dehydrogenase YP_002383234.1 2137769 R 585054 CDS YP_002383235.1 218549444 7123724 complement(2140610..2141467) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; glycosyltransferase 2141467 7123724 EFER_2113 Escherichia fergusonii ATCC 35469 glycosyltransferase YP_002383235.1 2140610 R 585054 CDS YP_002383236.1 218549445 7123844 complement(2141496..2142863) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93106949, 96326333, 7815923, 8759852; Product type e : enzyme; phosphomannomutase 2142863 cpsG 7123844 cpsG Escherichia fergusonii ATCC 35469 phosphomannomutase YP_002383236.1 2141496 R 585054 CDS YP_002383237.1 218549446 7124105 complement(2142867..2144324) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type e : enzyme; mannose-1-phosphate guanylyltransferase 2144324 7124105 EFER_2115 Escherichia fergusonii ATCC 35469 mannose-1-phosphate guanylyltransferase YP_002383237.1 2142867 R 585054 CDS YP_002383238.1 218549447 7121297 complement(2144308..2144811) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96326333, 10913267, 7592609, 7815923, 8759852; Product type e : enzyme; GDP-mannose mannosyl hydrolase 2144811 nudD 7121297 nudD Escherichia fergusonii ATCC 35469 GDP-mannose mannosyl hydrolase YP_002383238.1 2144308 R 585054 CDS YP_002383239.1 218549448 7119669 complement(2144811..2145776) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96326333, 98132401, 9862812, 7815923, 8759852, 9473059; Product type e : enzyme; bifunctional GDP-fucose synthetase: GDP-4-dehydro-6-deoxy-D-mannose epimerase and GDP-4-dehydro-6-L-deoxygalactose reductase 2145776 fcl 7119669 fcl Escherichia fergusonii ATCC 35469 bifunctional GDP-fucose synthetase: GDP-4-dehydro-6-deoxy-D-mannose epimerase and GDP-4-dehydro-6-L-deoxygalactose reductase YP_002383239.1 2144811 R 585054 CDS YP_002383240.1 218549449 7119992 complement(2145779..2146897) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20139699, 97400210, 10673432, 7815923, 8759852, 9257704, 14299611; Product type e : enzyme; GDP-D-mannose dehydratase 2146897 gmd 7119992 gmd Escherichia fergusonii ATCC 35469 GDP-D-mannose dehydratase YP_002383240.1 2145779 R 585054 CDS YP_002383241.1 218549450 7123186 complement(2146919..2147743) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2147743 7123186 EFER_2119 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383241.1 2146919 R 585054 CDS YP_002383242.1 218549451 7121298 complement(2148530..2149204) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2149204 7121298 EFER_2120 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383242.1 2148530 R 585054 CDS YP_002383243.1 218549452 7123297 complement(2149194..2150384) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2150384 7123297 EFER_2121 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383243.1 2149194 R 585054 CDS YP_002383244.1 218549453 7121299 complement(2150311..2151474) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2151474 7121299 EFER_2122 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383244.1 2150311 R 585054 CDS YP_002383245.1 218549454 7121300 complement(2151474..2152154) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; chloramphenicol acetyltransferase (fragment) 2152154 7121300 EFER_2123 Escherichia fergusonii ATCC 35469 chloramphenicol acetyltransferase (fragment) YP_002383245.1 2151474 R 585054 CDS YP_002383246.1 218549455 7121301 complement(2152138..2153079) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2153079 7121301 EFER_2124 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383246.1 2152138 R 585054 CDS YP_002383247.1 218549456 7121302 complement(2153080..2154369) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 2154369 7121302 EFER_2125 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383247.1 2153080 R 585054 CDS YP_002383248.1 218549457 7123298 complement(2154751..2155644) 1 NC_011740.1 together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP--glucose-1-phosphate uridylyltransferase subunit GalF 2155644 galF 7123298 galF Escherichia fergusonii ATCC 35469 UTP--glucose-1-phosphate uridylyltransferase subunit GalF YP_002383248.1 2154751 R 585054 CDS YP_002383249.1 218549458 7120165 complement(2155812..2157206) 1 NC_011740.1 WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid; colanic acid biosynthesis protein 2157206 wcaM 7120165 wcaM Escherichia fergusonii ATCC 35469 colanic acid biosynthesis protein YP_002383249.1 2155812 R 585054 CDS YP_002383250.1 218549459 7122372 complement(2157217..2158437) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96326333; Product type pe : enzyme; glycosyl transferase family protein 2158437 wcaL 7122372 wcaL Escherichia fergusonii ATCC 35469 glycosyl transferase family protein YP_002383250.1 2157217 R 585054 CDS YP_002383251.1 218549460 7124028 complement(2158434..2159714) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96326333, 8759852, 11004393; Product type pe : enzyme; pyruvyl transferase 2159714 wcaK 7124028 wcaK Escherichia fergusonii ATCC 35469 pyruvyl transferase YP_002383251.1 2158434 R 585054 CDS YP_002383252.1 218549461 7122371 complement(2159787..2161265) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96326333, 8759852; Product type pt : transporter; colanic acid exporter 2161265 wzxC 7122371 wzxC Escherichia fergusonii ATCC 35469 colanic acid exporter YP_002383252.1 2159787 R 585054 CDS YP_002383253.1 218549462 7122376 complement(2161267..2162661) 1 NC_011740.1 WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid; UDP-glucose lipid carrier transferase 2162661 wcaJ 7122376 wcaJ Escherichia fergusonii ATCC 35469 UDP-glucose lipid carrier transferase YP_002383253.1 2161267 R 585054 CDS YP_002383254.1 218549463 7122370 complement(2162716..2164086) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93106949, 96326333, 7815923, 8759852; Product type e : enzyme; phosphomannomutase 2164086 cpsG 7122370 cpsG Escherichia fergusonii ATCC 35469 phosphomannomutase YP_002383254.1 2162716 R 585054 CDS YP_002383255.1 218549464 7122797 complement(2164367..2165803) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 82100097, 85006781, 92048476, 93122523, 96326333, 7815923, 8759852; Product type e : enzyme; mannose-1-phosphate guanyltransferase 2165803 cpsB 7122797 cpsB Escherichia fergusonii ATCC 35469 mannose-1-phosphate guanyltransferase YP_002383255.1 2164367 R 585054 CDS YP_002383256.1 218549465 7122796 complement(2165806..2167029) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15670885, 96326333; Product type pe : enzyme; glycosyl transferase family protein 2167029 wcaI 7122796 wcaI Escherichia fergusonii ATCC 35469 glycosyl transferase family protein YP_002383256.1 2165806 R 585054 CDS YP_002383257.1 218549466 7122369 complement(2167026..2167505) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96326333, 10913267, 7592609, 7815923, 8759852; Product type e : enzyme; GDP-mannose mannosyl hydrolase 2167505 nudD 7122369 nudD Escherichia fergusonii ATCC 35469 GDP-mannose mannosyl hydrolase YP_002383257.1 2167026 R 585054 CDS YP_002383258.1 218549467 7119670 complement(2167508..2168473) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96326333, 98132401, 9862812, 7815923, 8759852, 9473059; Product type e : enzyme; bifunctional GDP-fucose synthetase: GDP-4-dehydro-6-deoxy-D-mannose epimerase and GDP-4-dehydro-6-L-deoxygalactose reductase 2168473 fcl 7119670 fcl Escherichia fergusonii ATCC 35469 bifunctional GDP-fucose synthetase: GDP-4-dehydro-6-deoxy-D-mannose epimerase and GDP-4-dehydro-6-L-deoxygalactose reductase YP_002383258.1 2167508 R 585054 CDS YP_002383259.1 218549468 7119993 complement(2168476..2169597) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20139699, 97400210, 10673432, 7815923, 8759852, 9257704, 14299611; Product type e : enzyme; GDP-D-mannose dehydratase 2169597 gmd 7119993 gmd Escherichia fergusonii ATCC 35469 GDP-D-mannose dehydratase YP_002383259.1 2168476 R 585054 CDS YP_002383260.1 218549469 7120593 complement(2169624..2170172) 1 NC_011740.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); colanic acid biosynthesis acetyltransferase WcaF 2170172 wcaF 7120593 wcaF Escherichia fergusonii ATCC 35469 colanic acid biosynthesis acetyltransferase WcaF YP_002383260.1 2169624 R 585054 CDS YP_002383261.1 218549470 7122368 complement(2170188..2170934) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11371548, 96326333, 8759852; Product type pe : enzyme; glycosyl transferase family protein 2170934 wcaE 7122368 wcaE Escherichia fergusonii ATCC 35469 glycosyl transferase family protein YP_002383261.1 2170188 R 585054 CDS YP_002383262.1 218549471 7123470 complement(2171060..2172352) 1 NC_011740.1 essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance; colanic acid biosynthesis protein 2172352 wcaD 7123470 wcaD Escherichia fergusonii ATCC 35469 colanic acid biosynthesis protein YP_002383262.1 2171060 R 585054 CDS YP_002383263.1 218549472 7122367 complement(2172255..2173472) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96326333; Product type pe : enzyme; glycosyl transferase family protein 2173472 wcaC 7122367 wcaC Escherichia fergusonii ATCC 35469 glycosyl transferase family protein YP_002383263.1 2172255 R 585054 CDS YP_002383264.1 218549473 7122366 complement(2173469..2173957) 1 NC_011740.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium; colanic acid biosynthesis acetyltransferase WcaB 2173957 wcaB 7122366 wcaB Escherichia fergusonii ATCC 35469 colanic acid biosynthesis acetyltransferase WcaB YP_002383264.1 2173469 R 585054 CDS YP_002383265.1 218549474 7122365 complement(2173960..2174799) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96326333; Product type pe : enzyme; glycosyl transferase family protein 2174799 wcaA 7122365 wcaA Escherichia fergusonii ATCC 35469 glycosyl transferase family protein YP_002383265.1 2173960 R 585054 CDS YP_002383266.1 218549475 7122364 complement(2174928..2177090) 1 NC_011740.1 Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide); tyrosine kinase 2177090 wzc 7122364 wzc Escherichia fergusonii ATCC 35469 tyrosine kinase YP_002383266.1 2174928 R 585054 CDS YP_002383267.1 218549476 7123471 complement(2177093..2177536) 1 NC_011740.1 Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis; tyrosine phosphatase 2177536 wzb 7123471 wzb Escherichia fergusonii ATCC 35469 tyrosine phosphatase YP_002383267.1 2177093 R 585054 CDS YP_002383268.1 218549477 7122375 complement(2177542..2178681) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15090537, 96326333, 8759852, 8763957; Product type lp : lipoprotein; lipoprotein 2178681 wza 7122375 wza Escherichia fergusonii ATCC 35469 lipoprotein YP_002383268.1 2177542 R 585054 CDS YP_002383269.1 218549478 7122374 2179340..2180923 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; membrane protein 2180923 yegH 7122374 yegH Escherichia fergusonii ATCC 35469 membrane protein YP_002383269.1 2179340 D 585054 CDS YP_002383270.1 218549479 7121554 complement(2180880..2181005) 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 2181005 7121554 EFER_2148 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383270.1 2180880 R 585054 CDS YP_002383271.1 218549480 7121303 2181187..2182212 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transposase, IS110 family 2182212 7121303 EFER_2149 Escherichia fergusonii ATCC 35469 transposase, IS110 family YP_002383271.1 2181187 D 585054 CDS YP_002383272.1 218549481 7121304 complement(2182761..2184614) 1 NC_011740.1 YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs; assembly protein 2184614 asmA 7121304 asmA Escherichia fergusonii ATCC 35469 assembly protein YP_002383272.1 2182761 R 585054 CDS YP_002383273.1 218549482 7120566 complement(2184636..2185217) 1 NC_011740.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 2185217 dcd 7120566 dcd Escherichia fergusonii ATCC 35469 deoxycytidine triphosphate deaminase YP_002383273.1 2184636 R 585054 CDS YP_002383274.1 218549483 7122870 complement(2185309..2185950) 1 NC_011740.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 2185950 udk 7122870 udk Escherichia fergusonii ATCC 35469 uridine kinase YP_002383274.1 2185309 R 585054 CDS YP_002383275.1 218549484 7122622 2186287..2189604 1 NC_011740.1 contains a MASE1 (Membrane-Associated Sensor) domain; potentially involved in signal transduction; sensor protein 2189604 yegE 7122622 yegE Escherichia fergusonii ATCC 35469 sensor protein YP_002383275.1 2186287 D 585054 CDS YP_002383276.1 218549485 7121553 complement(2189642..2190499) 1 NC_011740.1 inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine; 3-methyladenine DNA glycosylase 2190499 alkA 7121553 alkA Escherichia fergusonii ATCC 35469 3-methyladenine DNA glycosylase YP_002383276.1 2189642 R 585054 CDS YP_002383277.1 218549486 7123457 2190633..2191985 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 6094528, 7940673, 7984428; Product type pf : factor; chaperone 2191985 yegD 7123457 yegD Escherichia fergusonii ATCC 35469 chaperone YP_002383277.1 2190633 D 585054 CDS YP_002383278.1 218549487 7121552 complement(2191998..2193944) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2193944 yegI 7121552 yegI Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383278.1 2191998 R 585054 CDS YP_002383279.1 218549488 7121555 2194145..2194606 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2194606 yegJ 7121555 yegJ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383279.1 2194145 D 585054 CDS YP_002383280.1 218549489 7123886 complement(2194671..2195432) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2195432 yegK 7123886 yegK Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383280.1 2194671 R 585054 CDS YP_002383281.1 218549490 7123887 complement(2195429..2196088) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2196088 yegL 7123887 yegL Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383281.1 2195429 R 585054 CDS YP_002383282.1 218549491 7121176 2197296..2198543 1 NC_011740.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtA 2198543 mdtA 7121176 mdtA Escherichia fergusonii ATCC 35469 multidrug efflux system subunit MdtA YP_002383282.1 2197296 D 585054 CDS YP_002383283.1 218549492 7121247 2198543..2201665 1 NC_011740.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtB 2201665 mdtB 7121247 mdtB Escherichia fergusonii ATCC 35469 multidrug efflux system subunit MdtB YP_002383283.1 2198543 D 585054 CDS YP_002383284.1 218549493 7121248 2201666..2204743 1 NC_011740.1 Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtC 2204743 mdtC 7121248 mdtC Escherichia fergusonii ATCC 35469 multidrug efflux system subunit MdtC YP_002383284.1 2201666 D 585054 CDS YP_002383285.1 218549494 7121249 2204744..2206159 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12107134, 21450803, 8282725; Product type t : transporter; multidrug efflux system protein MdtE 2206159 mdtD 7121249 mdtD Escherichia fergusonii ATCC 35469 multidrug efflux system protein MdtE YP_002383285.1 2204744 D 585054 CDS YP_002383286.1 218549495 7121250 2206156..2207559 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94110256, 8282725; Product type r : regulator; signal transduction histidine-protein kinase BaeS 2207559 baeS 7121250 baeS Escherichia fergusonii ATCC 35469 signal transduction histidine-protein kinase BaeS YP_002383286.1 2206156 D 585054 CDS YP_002383287.1 218549496 7121643 2207556..2208278 1 NC_011740.1 response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport; DNA-binding transcriptional regulator BaeR 2208278 baeR 7121643 baeR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator BaeR YP_002383287.1 2207556 D 585054 CDS YP_002383288.1 218549497 7121642 2208458..2208790 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2208790 yegP 7121642 yegP Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383288.1 2208458 D 585054 CDS YP_002383289.1 218549498 7123888 2209034..2209285 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2209285 7123888 EFER_2169 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383289.1 2209034 D 585054 CDS YP_002383290.1 218549499 7121305 2209287..2209583 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2209583 7121305 EFER_2170 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383290.1 2209287 D 585054 CDS YP_002383291.1 218549500 7123299 2209686..2211047 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; peptidase 2211047 yegQ 7123299 yegQ Escherichia fergusonii ATCC 35469 peptidase YP_002383291.1 2209686 D 585054 CDS YP_002383292.1 218549501 7123820 2211304..2212203 1 NC_011740.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role; lipid kinase 2212203 yegS 7123820 yegS Escherichia fergusonii ATCC 35469 lipid kinase YP_002383292.1 2211304 D 585054 CDS YP_002383293.1 218549502 7121558 complement(2212277..2212975) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; phosphoglycolate phosphatase 2212975 7121558 EFER_2173 Escherichia fergusonii ATCC 35469 phosphoglycolate phosphatase YP_002383293.1 2212277 R 585054 CDS YP_002383294.1 218549503 7121306 complement(2212975..2214294) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type t : transporter; Ribitol transporter 2214294 7121306 EFER_2174 Escherichia fergusonii ATCC 35469 Ribitol transporter YP_002383294.1 2212975 R 585054 CDS YP_002383295.1 218549504 7121307 complement(2214321..2215784) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type e : enzyme; Xylulose kinase 2215784 7121307 EFER_2175 Escherichia fergusonii ATCC 35469 Xylulose kinase YP_002383295.1 2214321 R 585054 CDS YP_002383296.1 218549505 7121308 complement(2215798..2217210) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type e : enzyme; D-arabinitol 4-dehydrogenase 2217210 7121308 EFER_2176 Escherichia fergusonii ATCC 35469 D-arabinitol 4-dehydrogenase YP_002383296.1 2215798 R 585054 CDS YP_002383297.1 218549506 7121309 2217378..2218319 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type r : regulator; D-arabitol repressor 2218319 7121309 EFER_2177 Escherichia fergusonii ATCC 35469 D-arabitol repressor YP_002383297.1 2217378 D 585054 CDS YP_002383298.1 218549507 7121310 complement(2218322..2219353) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; catabolite repressor protein 2219353 7121310 EFER_2178 Escherichia fergusonii ATCC 35469 catabolite repressor protein YP_002383298.1 2218322 R 585054 CDS YP_002383299.1 218549508 7123845 2219512..2220264 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type e : enzyme; Ribitol 2-dehydrogenase 2220264 7123845 EFER_2179 Escherichia fergusonii ATCC 35469 Ribitol 2-dehydrogenase YP_002383299.1 2219512 D 585054 CDS YP_002383300.1 218549509 7121311 2220251..2221879 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type e : enzyme; Ribitol kinase 2221879 7121311 EFER_2180 Escherichia fergusonii ATCC 35469 Ribitol kinase YP_002383300.1 2220251 D 585054 CDS YP_002383301.1 218549510 7121312 2221981..2223255 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type t : transporter; Ribitol transporter 2223255 7121312 EFER_2181 Escherichia fergusonii ATCC 35469 Ribitol transporter YP_002383301.1 2221981 D 585054 CDS YP_002383302.1 218549511 7121313 complement(2223312..2224364) 1 NC_011740.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase 2224364 fbaB 7121313 fbaB Escherichia fergusonii ATCC 35469 fructose-bisphosphate aldolase YP_002383302.1 2223312 R 585054 CDS YP_002383303.1 218549512 7119991 2224392..2224541 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2224541 7119991 EFER_2183 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383303.1 2224392 D 585054 CDS YP_002383304.1 218549513 7121314 complement(2224531..2225874) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2225874 7121314 EFER_2184 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383304.1 2224531 R 585054 CDS YP_002383305.1 218549514 7123300 complement(2225875..2228580) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2228580 7123300 EFER_2185 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383305.1 2225875 R 585054 CDS YP_002383306.1 218549515 7121315 complement(2228605..2231292) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2231292 7121315 EFER_2186 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383306.1 2228605 R 585054 CDS YP_002383307.1 218549516 7123301 complement(2231280..2233853) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2233853 7123301 EFER_2187 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383307.1 2231280 R 585054 CDS YP_002383308.1 218549517 7121316 complement(2233939..2234856) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; membrane-bound hydrolase 2234856 yegX 7121316 yegX Escherichia fergusonii ATCC 35469 membrane-bound hydrolase YP_002383308.1 2233939 R 585054 CDS YP_002383309.1 218549518 7121559 complement(2234822..2235622) 1 NC_011740.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase 2235622 thiD 7121559 thiD Escherichia fergusonii ATCC 35469 phosphomethylpyrimidine kinase YP_002383309.1 2234822 R 585054 CDS YP_002383310.1 218549519 7121991 complement(2235619..2236407) 1 NC_011740.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 2236407 7121991 EFER_2190 Escherichia fergusonii ATCC 35469 hydroxyethylthiazole kinase YP_002383310.1 2235619 R 585054 CDS YP_002383311.1 218549520 7121317 2236426..2236587 1 NC_011740.1 hypothetical protein 2236587 7121317 EFER_2191 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383311.1 2236426 D 585054 CDS YP_002383312.1 218549521 7123302 2236821..2237165 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2237165 yohN 7123302 yohN Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383312.1 2236821 D 585054 CDS YP_002383313.1 218549522 7123368 complement(2237217..2238257) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 2238257 7123368 EFER_2193 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383313.1 2237217 R 585054 CDS YP_002383314.1 218549523 7121318 complement(2238261..2240744) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; Paral outer membrane protein, protein 2240744 7121318 EFER_2194 Escherichia fergusonii ATCC 35469 Paral outer membrane protein, protein YP_002383314.1 2238261 R 585054 CDS YP_002383315.1 218549524 7121319 complement(2240757..2241485) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; periplasmic chaperone protein , protein 2241485 7121319 EFER_2195 Escherichia fergusonii ATCC 35469 periplasmic chaperone protein , protein YP_002383315.1 2240757 R 585054 CDS YP_002383316.1 218549525 7121815 complement(2241491..2242024) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; Paral fimbrial-like protein 2242024 7121815 EFER_2196 Escherichia fergusonii ATCC 35469 Paral fimbrial-like protein YP_002383316.1 2241491 R 585054 CDS YP_002383317.1 218549526 7121877 complement(2242307..2242588) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2242588 7121877 EFER_2197 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383317.1 2242307 R 585054 CDS YP_002383318.1 218549527 7121878 complement(2242805..2243914) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91080852, 15601724, 2259334; Product type t : transporter; ATPase 2243914 mrp 7121878 mrp Escherichia fergusonii ATCC 35469 ATPase YP_002383318.1 2242805 R 585054 CDS YP_002383319.1 218549528 7120969 2244082..2246115 1 NC_011740.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 2246115 metG 7120969 metG Escherichia fergusonii ATCC 35469 methionyl-tRNA synthetase YP_002383319.1 2244082 D 585054 CDS YP_002383320.1 218549529 7120919 2246257..2250054 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2156810; Product type ph : phenotype; hypothetical protein 2250054 7120919 EFER_2200 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383320.1 2246257 D 585054 CDS YP_002383321.1 218549530 7121879 2250067..2253861 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2156810; Product type pr : regulator; Molybdate metabolism regulator (molR) 2253861 7121879 EFER_2201 Escherichia fergusonii ATCC 35469 Molybdate metabolism regulator (molR) YP_002383321.1 2250067 D 585054 CDS YP_002383322.1 218549531 7121880 2253871..2257515 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2257515 yehI 7121880 yehI Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383322.1 2253871 D 585054 CDS YP_002383323.1 218549532 7123341 2257575..2257892 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2257892 yehK 7123341 yehK Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383323.1 2257575 D 585054 CDS YP_002383324.1 218549533 7121560 2259203..2260291 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16428726; Product type pf : factor; ABC transporter protein 2260291 yehL 7121560 yehL Escherichia fergusonii ATCC 35469 ABC transporter protein YP_002383324.1 2259203 D 585054 CDS YP_002383325.1 218549534 7121561 2260302..2262581 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2262581 yehM 7121561 yehM Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383325.1 2260302 D 585054 CDS YP_002383326.1 218549535 7121562 2262574..2263710 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2263710 yehP 7121562 yehP Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383326.1 2262574 D 585054 CDS YP_002383327.1 218549536 7121563 2263602..2265701 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2265701 yehQ 7121563 yehQ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383327.1 2263602 D 585054 CDS YP_002383328.1 218549537 7121564 2265837..2266307 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2266307 7121564 EFER_2209 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383328.1 2265837 D 585054 CDS YP_002383329.1 218549538 7121881 complement(2266350..2266820) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2266820 yehS 7121881 yehS Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383329.1 2266350 R 585054 CDS YP_002383330.1 218549539 7121565 complement(2266867..2267586) 1 NC_011740.1 unknown function; when overproduced it confers drug-resistance; two-component response-regulatory protein YehT 2267586 yehT 7121565 yehT Escherichia fergusonii ATCC 35469 two-component response-regulatory protein YehT YP_002383330.1 2266867 R 585054 CDS YP_002383331.1 218549540 7119716 complement(2267583..2269268) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15522865, 15322361; Product type rc : receptor; sensory kinase in two-component system with YehT 2269268 yehU 7119716 yehU Escherichia fergusonii ATCC 35469 sensory kinase in two-component system with YehT YP_002383331.1 2267583 R 585054 CDS YP_002383332.1 218549541 7123048 2269490..2270221 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11489123; Product type r : regulator; DNA-binding transcriptional regulator 2270221 mlrA 7123048 mlrA Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YP_002383332.1 2269490 D 585054 CDS YP_002383333.1 218549542 7120937 2270281..2270388 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2270388 yohO 7120937 yohO Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383333.1 2270281 D 585054 CDS YP_002383334.1 218549543 7121736 complement(2270369..2271100) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter permease 2271100 yehW 7121736 yehW Escherichia fergusonii ATCC 35469 ABC transporter permease YP_002383334.1 2270369 R 585054 CDS YP_002383335.1 218549544 7119777 complement(2271105..2272031) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter ATP-binding protein 2272031 yehX 7119777 yehX Escherichia fergusonii ATCC 35469 ABC transporter ATP-binding protein YP_002383335.1 2271105 R 585054 CDS YP_002383336.1 218549545 7119778 complement(2272024..2273181) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter permease 2273181 yehY 7119778 yehY Escherichia fergusonii ATCC 35469 ABC transporter permease YP_002383336.1 2272024 R 585054 CDS YP_002383337.1 218549546 7119779 complement(2273188..2274105) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15251200; Product type pt : transporter; ABC transporter substrate-binding protein 2274105 yehZ 7119779 yehZ Escherichia fergusonii ATCC 35469 ABC transporter substrate-binding protein YP_002383337.1 2273188 R 585054 CDS YP_002383338.1 218549547 7119780 complement(2274254..2276551) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96303506; Product type e : enzyme; beta-D-glucoside glucohydrolase, periplasmic 2276551 bglX 7119780 bglX Escherichia fergusonii ATCC 35469 beta-D-glucoside glucohydrolase, periplasmic YP_002383338.1 2274254 R 585054 CDS YP_002383339.1 218549548 7121664 2276694..2278463 1 NC_011740.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase 2278463 dld 7121664 dld Escherichia fergusonii ATCC 35469 D-lactate dehydrogenase YP_002383339.1 2276694 D 585054 CDS YP_002383340.1 218549549 7122907 complement(2278502..2279434) 1 NC_011740.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7; D-alanyl-D-alanine endopeptidase 2279434 pbpG 7122907 pbpG Escherichia fergusonii ATCC 35469 D-alanyl-D-alanine endopeptidase YP_002383340.1 2278502 R 585054 CDS YP_002383341.1 218549550 7122559 complement(2279608..2280195) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2280195 yohC 7122559 yohC Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383341.1 2279608 R 585054 CDS YP_002383342.1 218549551 7121730 2280365..2280943 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2280943 yohD 7121730 yohD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383342.1 2280365 D 585054 CDS YP_002383343.1 218549552 7121731 complement(2281073..2281834) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; acetoin dehydrogenase 2281834 yohF 7121731 yohF Escherichia fergusonii ATCC 35469 acetoin dehydrogenase YP_002383343.1 2281073 R 585054 CDS YP_002383344.1 218549553 7121732 complement(2282102..2283052) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 22095566; Product type e : enzyme; tRNA-dihydrouridine synthase C 2283052 dusC 7121732 dusC Escherichia fergusonii ATCC 35469 tRNA-dihydrouridine synthase C YP_002383344.1 2282102 R 585054 CDS YP_002383345.1 218549554 7122929 2283329..2283727 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2283727 yohJ 7122929 yohJ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383345.1 2283329 D 585054 CDS YP_002383346.1 218549555 7121733 2283724..2284419 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2284419 yohK 7121733 yohK Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383346.1 2283724 D 585054 CDS YP_002383347.1 218549556 7121734 2284549..2285433 1 NC_011740.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 2285433 cdd 7121734 cdd Escherichia fergusonii ATCC 35469 cytidine deaminase YP_002383347.1 2284549 D 585054 CDS YP_002383348.1 218549557 7120874 2285580..2286299 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 96125233, 1567863, 8550448; hypothetical protein 2286299 sanA 7120874 sanA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383348.1 2285580 D 585054 CDS YP_002383349.1 218549558 7121189 2286302..2286541 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2286541 yeiS 7121189 yeiS Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383349.1 2286302 D 585054 CDS YP_002383350.1 218549559 7119791 2286860..2288098 1 NC_011740.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; oxidoreductase 2288098 yeiT 7119791 yeiT Escherichia fergusonii ATCC 35469 oxidoreductase YP_002383350.1 2286860 D 585054 CDS YP_002383351.1 218549560 7119792 2288092..2289327 1 NC_011740.1 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase 2289327 yeiA 7119792 yeiA Escherichia fergusonii ATCC 35469 dihydropyrimidine dehydrogenase YP_002383351.1 2288092 D 585054 CDS YP_002383352.1 218549561 7123592 complement(2289398..2290408) 1 NC_011740.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane protein 2290408 mglC 7123592 mglC Escherichia fergusonii ATCC 35469 beta-methylgalactoside transporter inner membrane protein YP_002383352.1 2289398 R 585054 CDS YP_002383353.1 218549562 7123242 complement(2290424..2291944) 1 NC_011740.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein 2291944 mglA 7123242 mglA Escherichia fergusonii ATCC 35469 galactose/methyl galaxtoside transporter ATP-binding protein YP_002383353.1 2290424 R 585054 CDS YP_002383354.1 218549563 7123777 complement(2292005..2293003) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87286407, 92049246, 1719366, 3057628, 3302609, 3600760, 6340108, 6885805, 7012152, 9298646; Product type t : transporter; methyl-galactoside ABC transporter periplasmic-binding protein 2293003 mglB 7123777 mglB Escherichia fergusonii ATCC 35469 methyl-galactoside ABC transporter periplasmic-binding protein YP_002383354.1 2292005 R 585054 CDS YP_002383355.1 218549564 7120928 complement(2293302..2294360) 1 NC_011740.1 negative regulator of the mglBAC operon for galactose utilization; DNA-binding transcriptional regulator GalS 2294360 galS 7120928 galS Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator GalS YP_002383355.1 2293302 R 585054 CDS YP_002383356.1 218549565 7120170 complement(2294468..2295625) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2295625 yeiB 7120170 yeiB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383356.1 2294468 R 585054 CDS YP_002383357.1 218549566 7119781 complement(2295642..2296310) 1 NC_011740.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 2296310 folE 7119781 folE Escherichia fergusonii ATCC 35469 GTP cyclohydrolase I YP_002383357.1 2295642 R 585054 CDS YP_002383358.1 218549567 7123003 2296567..2297403 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16567800; Product type e : enzyme; S-formylglutathione hydrolase 2297403 frmC 7123003 frmC Escherichia fergusonii ATCC 35469 S-formylglutathione hydrolase YP_002383358.1 2296567 D 585054 CDS YP_002383359.1 218549568 7124143 complement(2297434..2299413) 1 NC_011740.1 Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein; colicin I receptor 2299413 cirA 7124143 cirA Escherichia fergusonii ATCC 35469 colicin I receptor YP_002383359.1 2297434 R 585054 CDS YP_002383360.1 218549569 7123237 complement(2299696..2301165) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92250419, 94252996, 1315732, 7551055; Product type t : transporter; lysine transporter 2301165 lysP 7123237 lysP Escherichia fergusonii ATCC 35469 lysine transporter YP_002383360.1 2299696 R 585054 CDS YP_002383361.1 218549570 7121216 complement(2301334..2302203) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12400704, 1315732; Product type pr : regulator; DNA-binding transcriptional regulator 2302203 yeiE 7121216 yeiE Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YP_002383361.1 2301334 R 585054 CDS YP_002383362.1 218549571 7119783 2302303..2303352 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2303352 yeiH 7119783 yeiH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383362.1 2302303 D 585054 CDS YP_002383363.1 218549572 7119784 2303426..2304283 1 NC_011740.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 2304283 nfo 7119784 nfo Escherichia fergusonii ATCC 35469 endonuclease IV YP_002383363.1 2303426 D 585054 CDS YP_002383364.1 218549573 7123202 2304287..2305375 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 2305375 yeiI 7123202 yeiI Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383364.1 2304287 D 585054 CDS YP_002383365.1 218549574 7119785 complement(2305430..2306680) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; sodium/proton nucleoside transporter 2306680 yeiJ 7119785 yeiJ Escherichia fergusonii ATCC 35469 sodium/proton nucleoside transporter YP_002383365.1 2305430 R 585054 CDS YP_002383366.1 218549575 7119786 complement(2306694..2306810) 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 2306810 7119786 EFER_2247 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383366.1 2306694 R 585054 CDS YP_002383367.1 218549576 7121882 complement(2306780..2307721) 1 NC_011740.1 Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively; ribonucleoside hydrolase 2 2307721 rihB 7121882 rihB Escherichia fergusonii ATCC 35469 ribonucleoside hydrolase 2 YP_002383367.1 2306780 R 585054 CDS YP_002383368.1 218549577 7121410 2307890..2308549 1 NC_011740.1 activator of nucleoside metabolism; DNA-binding transcriptional activator YeiL 2308549 yeiL 7121410 yeiL Escherichia fergusonii ATCC 35469 DNA-binding transcriptional activator YeiL YP_002383368.1 2307890 D 585054 CDS YP_002383369.1 218549578 7123593 complement(2308618..2309868) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; sodium/proton nucleoside transporter 2309868 yeiM 7123593 yeiM Escherichia fergusonii ATCC 35469 sodium/proton nucleoside transporter YP_002383369.1 2308618 R 585054 CDS YP_002383370.1 218549579 7119787 complement(2309962..2310900) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2310900 yeiN 7119787 yeiN Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383370.1 2309962 R 585054 CDS YP_002383371.1 218549580 7119788 complement(2310888..2311934) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 2311934 yeiC 7119788 yeiC Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383371.1 2310888 R 585054 CDS YP_002383372.1 218549581 7119782 complement(2312253..2313980) 1 NC_011740.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system fructose-specific transporter subunit IIBC 2313980 fruA 7119782 fruA Escherichia fergusonii ATCC 35469 PTS system fructose-specific transporter subunit IIBC YP_002383372.1 2312253 R 585054 CDS YP_002383373.1 218549582 7123015 complement(2313955..2314893) 1 NC_011740.1 converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; 1-phosphofructokinase 2314893 fruK 7123015 fruK Escherichia fergusonii ATCC 35469 1-phosphofructokinase YP_002383373.1 2313955 R 585054 CDS YP_002383374.1 218549583 7123571 complement(2314893..2316023) 1 NC_011740.1 phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr; PTS system fructose-specific transporter subunit IIA/HPr protein 2316023 fruB 7123571 fruB Escherichia fergusonii ATCC 35469 PTS system fructose-specific transporter subunit IIA/HPr protein YP_002383374.1 2314893 R 585054 CDS YP_002383375.1 218549584 7123016 2316288..2317547 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10438463, 10209755; Product type t : transporter; lactose/glucose efflux system 2317547 setB 7123016 setB Escherichia fergusonii ATCC 35469 lactose/glucose efflux system YP_002383375.1 2316288 D 585054 CDS YP_002383376.1 218549585 7121773 complement(2317544..2317798) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2317798 yeiW 7121773 yeiW Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383376.1 2317544 R 585054 CDS YP_002383377.1 218549586 7119794 2317955..2318527 1 NC_011740.1 Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; elongation factor P 2318527 yeiP 7119794 yeiP Escherichia fergusonii ATCC 35469 elongation factor P YP_002383377.1 2317955 D 585054 CDS YP_002383378.1 218549587 7119789 complement(2318576..2319904) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; IS4 transposase; KpLE2 phage-like element 2319904 insG 7119789 insG Escherichia fergusonii ATCC 35469 IS4 transposase; KpLE2 phage-like element YP_002383378.1 2318576 R 585054 CDS YP_002383379.1 218549588 7123214 2320154..2321629 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; sugar dehydrogenase 2321629 yeiQ 7123214 yeiQ Escherichia fergusonii ATCC 35469 sugar dehydrogenase YP_002383379.1 2320154 D 585054 CDS YP_002383380.1 218549589 7119790 2321741..2322733 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 2322733 yeiR 7119790 yeiR Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383380.1 2321741 D 585054 CDS YP_002383381.1 218549590 7123594 2322770..2323483 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; undecaprenyl pyrophosphate phosphatase 2323483 yeiU 7123594 yeiU Escherichia fergusonii ATCC 35469 undecaprenyl pyrophosphate phosphatase YP_002383381.1 2322770 D 585054 CDS YP_002383382.1 218549591 7119793 2323897..2324463 1 NC_011740.1 by similarity, Spr seems to have peptidase activity; involved in thermoresistance; outer membrane lipoprotein 2324463 spr 7119793 spr Escherichia fergusonii ATCC 35469 outer membrane lipoprotein YP_002383382.1 2323897 D 585054 CDS YP_002383383.1 218549592 7121810 2324646..2326202 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type pm : membrane component; hypothetical protein 2326202 7121810 EFER_2266 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383383.1 2324646 D 585054 CDS YP_002383384.1 218549593 7121883 2326239..2328095 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; oligopeptide ABC transporter substrate-binding protein 2328095 yejA 7121883 yejA Escherichia fergusonii ATCC 35469 oligopeptide ABC transporter substrate-binding protein YP_002383384.1 2326239 D 585054 CDS YP_002383385.1 218549594 7119795 2328096..2329190 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; oligopeptide ABC transporter permease 2329190 yejB 7119795 yejB Escherichia fergusonii ATCC 35469 oligopeptide ABC transporter permease YP_002383385.1 2328096 D 585054 CDS YP_002383386.1 218549595 7119796 2329190..2330215 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; oligopeptide ABC transporter permease 2330215 yejE 7119796 yejE Escherichia fergusonii ATCC 35469 oligopeptide ABC transporter permease YP_002383386.1 2329190 D 585054 CDS YP_002383387.1 218549596 7119797 2330169..2331806 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; oligopeptide ABC transporter ATP-binding protein 2331806 yejF 7119797 yejF Escherichia fergusonii ATCC 35469 oligopeptide ABC transporter ATP-binding protein YP_002383387.1 2330169 D 585054 CDS YP_002383388.1 218549597 7123049 complement(2331810..2332172) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2332172 yejG 7123049 yejG Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383388.1 2331810 R 585054 CDS YP_002383389.1 218549598 7123050 complement(2332483..2333673) 1 NC_011740.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system protein 2333673 bcr 7123050 bcr Escherichia fergusonii ATCC 35469 bicyclomycin/multidrug efflux system protein YP_002383389.1 2332483 R 585054 CDS YP_002383390.1 218549599 7121648 complement(2333701..2334396) 1 NC_011740.1 catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA; 16S rRNA pseudouridylate synthase A 2334396 rsuA 7121648 rsuA Escherichia fergusonii ATCC 35469 16S rRNA pseudouridylate synthase A YP_002383390.1 2333701 R 585054 CDS YP_002383391.1 218549600 7121154 2334545..2336305 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; nucleic acid ATP-dependent helicase 2336305 yejH 7121154 yejH Escherichia fergusonii ATCC 35469 nucleic acid ATP-dependent helicase YP_002383391.1 2334545 D 585054 CDS YP_002383392.1 218549601 7119798 2336430..2336714 1 NC_011740.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 2336714 rplY 7119798 rplY Escherichia fergusonii ATCC 35469 50S ribosomal protein L25 YP_002383392.1 2336430 D 585054 CDS YP_002383393.1 218549602 7121111 complement(2336912..2337796) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hydrolase 2337796 7121111 EFER_2276 Escherichia fergusonii ATCC 35469 hydrolase YP_002383393.1 2336912 R 585054 CDS YP_002383394.1 218549603 7123941 complement(2338117..2339121) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99296598, 10368163; Product type f : factor; nucleoid-associated protein NdpA 2339121 yejK 7123941 yejK Escherichia fergusonii ATCC 35469 nucleoid-associated protein NdpA YP_002383394.1 2338117 R 585054 CDS YP_002383395.1 218549604 7119799 2339303..2339530 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2339530 yejL 7119799 yejL Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383395.1 2339303 D 585054 CDS YP_002383396.1 218549605 7119800 2339561..2341321 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hydrolase 2341321 yejM 7119800 yejM Escherichia fergusonii ATCC 35469 hydrolase YP_002383396.1 2339561 D 585054 CDS YP_002383397.1 218549606 7120036 2341945..2342322 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2342322 7120036 EFER_2281 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383397.1 2341945 D 585054 CDS YP_002383398.1 218549607 7121884 2342326..2342658 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2342658 ymgD 7121884 ymgD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383398.1 2342326 D 585054 CDS YP_002383399.1 218549608 7121689 2342911..2343561 1 NC_011740.1 nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes; transcriptional regulator NarP 2343561 narP 7121689 narP Escherichia fergusonii ATCC 35469 transcriptional regulator NarP YP_002383399.1 2342911 D 585054 CDS YP_002383400.1 218549609 7123201 complement(2343601..2344653) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 11756453, 12196152, 87260957, 91194558, 95362656, 9914305, 7635817; Product type pe : enzyme; heme lyase, CcmH subunit 2344653 ccmH 7123201 ccmH Escherichia fergusonii ATCC 35469 heme lyase, CcmH subunit YP_002383400.1 2343601 R 585054 CDS YP_002383401.1 218549610 7123768 complement(2344650..2345207) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 12196152, 9716493, 9770295, 11256948, 11350062, 11843181, 7635817, 9537397; Product type e : enzyme; periplasmic thioredoxin of cytochrome c-type biogenesis 2345207 ccmG 7123768 ccmG Escherichia fergusonii ATCC 35469 periplasmic thioredoxin of cytochrome c-type biogenesis YP_002383401.1 2344650 R 585054 CDS YP_002383402.1 218549611 7120872 complement(2345204..2347147) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 11756453, 12196152, 87260957, 8842153, 91194558, 95362656, 9716493, 7635817; Product type e : enzyme; heme lyase, CcmF subunit 2347147 ccmF 7120872 ccmF Escherichia fergusonii ATCC 35469 heme lyase, CcmF subunit YP_002383402.1 2345204 R 585054 CDS YP_002383403.1 218549612 7120871 complement(2347144..2347623) 1 NC_011740.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 2347623 ccmE 7120871 ccmE Escherichia fergusonii ATCC 35469 cytochrome c-type biogenesis protein CcmE YP_002383403.1 2347144 R 585054 CDS YP_002383404.1 218549613 7120870 complement(2347620..2347829) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 12196152, 95362656, 9716493, 7635817; Product type f : factor; cytochrome c biogenesis protein 2347829 ccmD 7120870 ccmD Escherichia fergusonii ATCC 35469 cytochrome c biogenesis protein YP_002383404.1 2347620 R 585054 CDS YP_002383405.1 218549614 7120869 complement(2347826..2348563) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 12196152, 14532274, 21413853, 95362656, 7635817; Product type t : transporter; heme ABC transporter membrane protein 2348563 ccmC 7120869 ccmC Escherichia fergusonii ATCC 35469 heme ABC transporter membrane protein YP_002383405.1 2347826 R 585054 CDS YP_002383406.1 218549615 7123767 complement(2348605..2349267) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 12196152, 95362656, 9716493, 7635817; Product type t : transporter; heme ABC transporter membrane protein 2349267 ccmB 7123767 ccmB Escherichia fergusonii ATCC 35469 heme ABC transporter membrane protein YP_002383406.1 2348605 R 585054 CDS YP_002383407.1 218549616 7120868 complement(2349264..2349887) 1 NC_011740.1 ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 2349887 ccmA 7120868 ccmA Escherichia fergusonii ATCC 35469 cytochrome c biogenesis protein CcmA YP_002383407.1 2349264 R 585054 CDS YP_002383408.1 218549617 7120867 complement(2349902..2350504) 1 NC_011740.1 with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone; cytochrome c-type protein NapC 2350504 napC 7120867 napC Escherichia fergusonii ATCC 35469 cytochrome c-type protein NapC YP_002383408.1 2349902 R 585054 CDS YP_002383409.1 218549618 7123734 complement(2350514..2350963) 1 NC_011740.1 small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA; citrate reductase cytochrome c-type subunit 2350963 napB 7123734 napB Escherichia fergusonii ATCC 35469 citrate reductase cytochrome c-type subunit YP_002383409.1 2350514 R 585054 CDS YP_002383410.1 218549619 7120671 complement(2350960..2351823) 1 NC_011740.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane component 2351823 napH 7120671 napH Escherichia fergusonii ATCC 35469 quinol dehydrogenase membrane component YP_002383410.1 2350960 R 585054 CDS YP_002383411.1 218549620 7120674 complement(2351810..2352505) 1 NC_011740.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic component 2352505 napG 7120674 napG Escherichia fergusonii ATCC 35469 quinol dehydrogenase periplasmic component YP_002383411.1 2351810 R 585054 CDS YP_002383412.1 218549621 7120673 complement(2352512..2354998) 1 NC_011740.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit 2354998 napA 7120673 napA Escherichia fergusonii ATCC 35469 nitrate reductase catalytic subunit YP_002383412.1 2352512 R 585054 CDS YP_002383413.1 218549622 7120670 complement(2354995..2355258) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96228696, 99395037; Product type f : factor; assembly protein for periplasmic nitrate reductase 2355258 napD 7120670 napD Escherichia fergusonii ATCC 35469 assembly protein for periplasmic nitrate reductase YP_002383413.1 2354995 R 585054 CDS YP_002383414.1 218549623 7123735 complement(2355248..2355742) 1 NC_011740.1 Predicted role in electron transfer to the periplasmic nitrate reductase protein NapA.; ferredoxin-type protein 2355742 napF 7123735 napF Escherichia fergusonii ATCC 35469 ferredoxin-type protein YP_002383414.1 2355248 R 585054 CDS YP_002383415.1 218549624 7120672 2356147..2356635 1 NC_011740.1 serine protease inhibitor, inhibits trypsin and other proteases; ecotin 2356635 eco 7120672 eco Escherichia fergusonii ATCC 35469 ecotin YP_002383415.1 2356147 D 585054 CDS YP_002383416.1 218549625 7122935 2356816..2359041 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 2359041 ybiO 7122935 ybiO Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383416.1 2356816 D 585054 CDS YP_002383417.1 218549626 7122100 complement(2359038..2359964) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; SAM-dependent methyltransferase 2359964 ybiN 7122100 ybiN Escherichia fergusonii ATCC 35469 SAM-dependent methyltransferase YP_002383417.1 2359038 R 585054 CDS YP_002383418.1 218549627 7123425 2360095..2360499 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2360499 ybiM 7123425 ybiM Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383418.1 2360095 D 585054 CDS YP_002383419.1 218549628 7122099 2360764..2363046 1 NC_011740.1 Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; catecholate siderophore receptor Fiu 2363046 fiu 7122099 fiu Escherichia fergusonii ATCC 35469 catecholate siderophore receptor Fiu YP_002383419.1 2360764 D 585054 CDS YP_002383420.1 218549629 7123629 2363088..2363765 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hydroxylase 2363765 ybiX 7123629 ybiX Escherichia fergusonii ATCC 35469 hydroxylase YP_002383420.1 2363088 D 585054 CDS YP_002383421.1 218549630 7122104 2363839..2364105 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2364105 ybiI 7122104 ybiI Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383421.1 2363839 D 585054 CDS YP_002383422.1 218549631 7122097 2364370..2364630 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2364630 ybiJ 7122097 ybiJ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383422.1 2364370 D 585054 CDS YP_002383423.1 218549632 7122098 complement(2364772..2365857) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8405966; Product type pe : enzyme; hypothetical protein 2365857 ybiC 7122098 ybiC Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383423.1 2364772 R 585054 CDS YP_002383424.1 218549633 7122095 complement(2365998..2366960) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; glycosyl transferase family protein 2366960 ybiB 7122095 ybiB Escherichia fergusonii ATCC 35469 glycosyl transferase family protein YP_002383424.1 2365998 R 585054 CDS YP_002383425.1 218549634 7122094 complement(2366988..2369138) 1 NC_011740.1 helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG 2369138 dinG 7122094 dinG Escherichia fergusonii ATCC 35469 ATP-dependent DNA helicase DinG YP_002383425.1 2366988 R 585054 CDS YP_002383426.1 218549635 7122899 2369258..2369740 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2369740 ybiA 7122899 ybiA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383426.1 2369258 D 585054 CDS YP_002383427.1 218549636 7123424 complement(2369972..2371336) 1 NC_011740.1 this helicase is not essential cell growth; ATP-dependent RNA helicase RhlE 2371336 rhlE 7123424 rhlE Escherichia fergusonii ATCC 35469 ATP-dependent RNA helicase RhlE YP_002383427.1 2369972 R 585054 CDS YP_002383428.1 218549637 7123315 2371565..2372236 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator 2372236 ybiH 7123315 ybiH Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YP_002383428.1 2371565 D 585054 CDS YP_002383429.1 218549638 7122096 2372236..2373234 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16092522; Product type pt : transporter; hypothetical protein 2373234 ybhG 7122096 ybhG Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383429.1 2372236 D 585054 CDS YP_002383430.1 218549639 7123976 2373227..2374963 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter ATP-binding protein 2374963 ybhF 7123976 ybhF Escherichia fergusonii ATCC 35469 ABC transporter ATP-binding protein YP_002383430.1 2373227 D 585054 CDS YP_002383431.1 218549640 7123975 2374956..2376089 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter permease 2376089 ybhS 7123975 ybhS Escherichia fergusonii ATCC 35469 ABC transporter permease YP_002383431.1 2374956 D 585054 CDS YP_002383432.1 218549641 7122093 2376100..2377206 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter permease 2377206 ybhR 7122093 ybhR Escherichia fergusonii ATCC 35469 ABC transporter permease YP_002383432.1 2376100 D 585054 CDS YP_002383433.1 218549642 7122092 complement(2377168..2377578) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2377578 ybhQ 7122092 ybhQ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383433.1 2377168 R 585054 CDS YP_002383434.1 218549643 7122091 2377711..2378472 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; metal-dependent hydrolase 2378472 ybhP 7122091 ybhP Escherichia fergusonii ATCC 35469 metal-dependent hydrolase YP_002383434.1 2377711 D 585054 CDS YP_002383435.1 218549644 7122090 2378469..2379710 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20102623, 10634942; Product type e : enzyme; cardiolipin synthase 2 2379710 ybhO 7122090 ybhO Escherichia fergusonii ATCC 35469 cardiolipin synthase 2 YP_002383435.1 2378469 D 585054 CDS YP_002383436.1 218549645 7122089 2379710..2380666 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2380666 ybhN 7122089 ybhN Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383436.1 2379710 D 585054 CDS YP_002383437.1 218549646 7123978 complement(2380670..2380933) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2380933 7123978 EFER_2321 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383437.1 2380670 R 585054 CDS YP_002383438.1 218549647 7121885 complement(2380905..2381273) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2381273 7121885 EFER_2322 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383438.1 2380905 R 585054 CDS YP_002383439.1 218549648 7123942 complement(2381320..2382141) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2382141 ybhM 7123942 ybhM Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383439.1 2381320 R 585054 CDS YP_002383440.1 218549649 7123977 complement(2382232..2383893) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transmembrane protein (N-terminal); phosphatase (C-terminal) 2383893 7123977 EFER_2324 Escherichia fergusonii ATCC 35469 transmembrane protein (N-terminal); phosphatase (C-terminal) YP_002383440.1 2382232 R 585054 CDS YP_002383441.1 218549650 7121886 complement(2384256..2384960) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2384960 ybhL 7121886 ybhL Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383441.1 2384256 R 585054 CDS YP_002383442.1 218549651 7122088 complement(2385007..2385459) 1 NC_011740.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin guanine dinucleotide biosynthesis protein MoaE 2385459 moaE 7122088 moaE Escherichia fergusonii ATCC 35469 molybdopterin guanine dinucleotide biosynthesis protein MoaE YP_002383442.1 2385007 R 585054 CDS YP_002383443.1 218549652 7120947 complement(2385461..2385706) 1 NC_011740.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit 2385706 moaD 7120947 moaD Escherichia fergusonii ATCC 35469 molybdopterin synthase small subunit YP_002383443.1 2385461 R 585054 CDS YP_002383444.1 218549653 7123246 complement(2385699..2386184) 1 NC_011740.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 2386184 moaC 7123246 moaC Escherichia fergusonii ATCC 35469 molybdenum cofactor biosynthesis protein MoaC YP_002383444.1 2385699 R 585054 CDS YP_002383445.1 218549654 7123245 complement(2386187..2386699) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93368423; Product type pf : factor; molybdopterin biosynthesis protein B 2386699 moaB 7123245 moaB Escherichia fergusonii ATCC 35469 molybdopterin biosynthesis protein B YP_002383445.1 2386187 R 585054 CDS YP_002383446.1 218549655 7120946 complement(2386721..2387710) 1 NC_011740.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 2387710 moaA 7120946 moaA Escherichia fergusonii ATCC 35469 molybdenum cofactor biosynthesis protein A YP_002383446.1 2386721 R 585054 CDS YP_002383447.1 218549656 7123780 2388107..2389015 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16272399; Product type pe : enzyme; transferase 2389015 ybhK 7123780 ybhK Escherichia fergusonii ATCC 35469 transferase YP_002383447.1 2388107 D 585054 CDS YP_002383448.1 218549657 7122087 complement(2389053..2391074) 1 NC_011740.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 2391074 uvrB 7122087 uvrB Escherichia fergusonii ATCC 35469 excinuclease ABC subunit B YP_002383448.1 2389053 R 585054 CDS YP_002383449.1 218549658 7122646 complement(2391647..2392336) 1 NC_011740.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 2392336 bioD 7122646 bioD Escherichia fergusonii ATCC 35469 dithiobiotin synthetase YP_002383449.1 2391647 R 585054 CDS YP_002383450.1 218549659 7121668 complement(2392323..2393078) 1 NC_011740.1 methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth; biotin biosynthesis protein BioC 2393078 bioC 7121668 bioC Escherichia fergusonii ATCC 35469 biotin biosynthesis protein BioC YP_002383450.1 2392323 R 585054 CDS YP_002383451.1 218549660 7121667 2393053..2393130 1 NC_011740.1 hypothetical protein 2393130 7121667 EFER_2336 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383451.1 2393053 D 585054 CDS YP_002383452.1 218549661 7121887 complement(2393065..2394219) 1 NC_011740.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 2394219 bioF 7121887 bioF Escherichia fergusonii ATCC 35469 8-amino-7-oxononanoate synthase YP_002383452.1 2393065 R 585054 CDS YP_002383453.1 218549662 7121669 complement(2394216..2395256) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11834738, 12475249, 14704425, 14967041, 20250955, 89066784, 94170810, 94190882, 97382445, 11686925; Product type e : enzyme; biotin synthase 2395256 bioB 7121669 bioB Escherichia fergusonii ATCC 35469 biotin synthase YP_002383453.1 2394216 R 585054 CDS YP_002383454.1 218549663 7121666 2395343..2396632 1 NC_011740.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 2396632 bioA 7121666 bioA Escherichia fergusonii ATCC 35469 adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_002383454.1 2395343 D 585054 CDS YP_002383455.1 218549664 7121665 2396691..2397167 1 NC_011740.1 YbhB; similar to rat and human kinase inhibitory proteins; kinase inhibitor protein 2397167 ybhB 7121665 ybhB Escherichia fergusonii ATCC 35469 kinase inhibitor protein YP_002383455.1 2396691 D 585054 CDS YP_002383456.1 218549665 7123974 2397319..2398602 1 NC_011740.1 outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase family; pectinesterase 2398602 ybhC 7123974 ybhC Escherichia fergusonii ATCC 35469 pectinesterase YP_002383456.1 2397319 D 585054 CDS YP_002383457.1 218549666 7122086 complement(2398747..2399742) 1 NC_011740.1 catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; 6-phosphogluconolactonase 2399742 pgl 7122086 pgl Escherichia fergusonii ATCC 35469 6-phosphogluconolactonase YP_002383457.1 2398747 R 585054 CDS YP_002383458.1 218549667 7122589 2399909..2400727 1 NC_011740.1 YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily; phosphotransferase 2400727 ybhA 7122589 ybhA Escherichia fergusonii ATCC 35469 phosphotransferase YP_002383458.1 2399909 D 585054 CDS YP_002383459.1 218549668 7122085 complement(2400728..2401786) 1 NC_011740.1 Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein 2401786 modC 7122085 modC Escherichia fergusonii ATCC 35469 molybdate transporter ATP-binding protein YP_002383459.1 2400728 R 585054 CDS YP_002383460.1 218549669 7120951 complement(2401789..2402478) 1 NC_011740.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 2402478 modB 7120951 modB Escherichia fergusonii ATCC 35469 molybdate ABC transporter permease YP_002383460.1 2401789 R 585054 CDS YP_002383461.1 218549670 7120950 complement(2402478..2403254) 1 NC_011740.1 with ModCB is involved in the high-affinity transport of molybdate; molybdate transporter periplasmic protein 2403254 modA 7120950 modA Escherichia fergusonii ATCC 35469 molybdate transporter periplasmic protein YP_002383461.1 2402478 R 585054 CDS YP_002383462.1 218549671 7120949 complement(2403399..2403650) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; outer membrane or exported 2403650 7120949 EFER_2347 Escherichia fergusonii ATCC 35469 outer membrane or exported YP_002383462.1 2403399 R 585054 CDS YP_002383463.1 218549672 7121888 2403677..2404465 1 NC_011740.1 represses the modABCD operon and activates the moaABCD and napFDAGHBC operons; DNA-binding transcriptional regulator ModE 2404465 modE 7121888 modE Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator ModE YP_002383463.1 2403677 D 585054 CDS YP_002383464.1 218549673 7120952 2404533..2406005 1 NC_011740.1 contains 2 ATP-binding cassettes; involved in the transport of molybdenum; molybdenum transport ATP-binding protein ModF 2406005 modF 7120952 modF Escherichia fergusonii ATCC 35469 molybdenum transport ATP-binding protein ModF YP_002383464.1 2404533 D 585054 CDS YP_002383465.1 218549674 7120953 2406266..2407282 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89274199, 92253563, 92338916, 3022232, 6301942, 8564363, 8611559, 8931134, 9174344, 9271499, 9708982; Product type e : enzyme; UDP-galactose-4-epimerase 2407282 galE 7120953 galE Escherichia fergusonii ATCC 35469 UDP-galactose-4-epimerase YP_002383465.1 2406266 D 585054 CDS YP_002383466.1 218549675 7120164 2407292..2408338 1 NC_011740.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase 2408338 galT 7120164 galT Escherichia fergusonii ATCC 35469 galactose-1-phosphate uridylyltransferase YP_002383466.1 2407292 D 585054 CDS YP_002383467.1 218549676 7120171 2408342..2409490 1 NC_011740.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 2409490 galK 7120171 galK Escherichia fergusonii ATCC 35469 galactokinase YP_002383467.1 2408342 D 585054 CDS YP_002383468.1 218549677 7120166 2409484..2410524 1 NC_011740.1 catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase 2410524 galM 7120166 galM Escherichia fergusonii ATCC 35469 aldose 1-epimerase YP_002383468.1 2409484 D 585054 CDS YP_002383469.1 218549678 7120167 2410727..2411479 1 NC_011740.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 2411479 gpmA 7120167 gpmA Escherichia fergusonii ATCC 35469 phosphoglyceromutase YP_002383469.1 2410727 D 585054 CDS YP_002383470.1 218549679 7123187 complement(2411457..2411552) 1 NC_011740.1 hypothetical protein 2411552 7123187 EFER_2355 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383470.1 2411457 R 585054 CDS YP_002383471.1 218549680 7121889 complement(2411620..2412672) 1 NC_011740.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 2412672 aroG 7121889 aroG Escherichia fergusonii ATCC 35469 phospho-2-dehydro-3-deoxyheptonate aldolase YP_002383471.1 2411620 R 585054 CDS YP_002383472.1 218549681 7120549 2412988..2413368 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2413368 ybgS 7120549 ybgS Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383472.1 2412988 D 585054 CDS YP_002383473.1 218549682 7122084 2413482..2414417 1 NC_011740.1 involved in zinc efflux across the cytoplasmic membrane; zinc transporter ZitB 2414417 zitB 7122084 zitB Escherichia fergusonii ATCC 35469 zinc transporter ZitB YP_002383473.1 2413482 D 585054 CDS YP_002383474.1 218549683 7123047 complement(2414414..2415133) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 219824, 90330519; Product type t : transporter; nicotinamide mononucleotide transporter 2415133 pnuC 7123047 pnuC Escherichia fergusonii ATCC 35469 nicotinamide mononucleotide transporter YP_002383474.1 2414414 R 585054 CDS YP_002383475.1 218549684 7120095 complement(2415171..2416214) 1 NC_011740.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 2416214 nadA 7120095 nadA Escherichia fergusonii ATCC 35469 quinolinate synthetase YP_002383475.1 2415171 R 585054 CDS YP_002383476.1 218549685 7120071 complement(2417459..2418250) 1 NC_011740.1 periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity; tol-pal system protein YbgF 2418250 ybgF 7120071 ybgF Escherichia fergusonii ATCC 35469 tol-pal system protein YbgF YP_002383476.1 2417459 R 585054 CDS YP_002383477.1 218549686 7122077 complement(2418260..2418781) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11790745, 87133578, 92244043, 99403391, 11173492, 2687247; Product type lp : lipoprotein; peptidoglycan-associated outer membrane lipoprotein 2418781 pal 7122077 pal Escherichia fergusonii ATCC 35469 peptidoglycan-associated outer membrane lipoprotein YP_002383477.1 2418260 R 585054 CDS YP_002383478.1 218549687 7122551 complement(2418816..2420108) 1 NC_011740.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 2420108 tolB 7122551 tolB Escherichia fergusonii ATCC 35469 translocation protein TolB YP_002383478.1 2418816 R 585054 CDS YP_002383479.1 218549688 7122140 complement(2420241..2421452) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type m : membrane component; TolA protein 2421452 7122140 EFER_2365 Escherichia fergusonii ATCC 35469 TolA protein YP_002383479.1 2420241 R 585054 CDS YP_002383480.1 218549689 7121890 complement(2421515..2421943) 1 NC_011740.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR 2421943 tolR 7121890 tolR Escherichia fergusonii ATCC 35469 colicin uptake protein TolR YP_002383480.1 2421515 R 585054 CDS YP_002383481.1 218549690 7122142 complement(2421947..2422639) 1 NC_011740.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolQ 2422639 tolQ 7122142 tolQ Escherichia fergusonii ATCC 35469 colicin uptake protein TolQ YP_002383481.1 2421947 R 585054 CDS YP_002383482.1 218549691 7123430 complement(2422636..2423040) 1 NC_011740.1 catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components; acyl-CoA thioester hydrolase YbgC 2423040 ybgC 7123430 ybgC Escherichia fergusonii ATCC 35469 acyl-CoA thioester hydrolase YbgC YP_002383482.1 2422636 R 585054 CDS YP_002383483.1 218549692 7122075 complement(2423190..2423483) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2423483 ybgE 7122075 ybgE Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383483.1 2423190 R 585054 CDS YP_002383484.1 218549693 7122076 complement(2423611..2424750) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87299685, 89255232, 91035243, 2843510, 3138232; Product type c : carrier; cytochrome d terminal oxidase subunit II 2424750 cydB 7122076 cydB Escherichia fergusonii ATCC 35469 cytochrome d terminal oxidase subunit II YP_002383484.1 2423611 R 585054 CDS YP_002383485.1 218549694 7122840 complement(2424766..2426334) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87299685, 89255232, 91035243, 1689724, 1724280, 2843510, 3138232; Product type c : carrier; cytochrome d terminal oxidase subunit I 2426334 cydA 7122840 cydA Escherichia fergusonii ATCC 35469 cytochrome d terminal oxidase subunit I YP_002383485.1 2424766 R 585054 CDS YP_002383486.1 218549695 7122839 complement(2427185..2429818) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14645248, 9063979; Product type e : enzyme; alpha-mannosidase 2429818 mngB 7122839 mngB Escherichia fergusonii ATCC 35469 alpha-mannosidase YP_002383486.1 2427185 R 585054 CDS YP_002383487.1 218549696 7120942 complement(2429838..2431766) 1 NC_011740.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC 2431766 mngA 7120942 mngA Escherichia fergusonii ATCC 35469 PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC YP_002383487.1 2429838 R 585054 CDS YP_002383488.1 218549697 7120941 2431924..2432643 1 NC_011740.1 regulates the succiny-lCoA synthetase operon; DNA-binding transcriptional repressor MngR 2432643 mngR 7120941 mngR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional repressor MngR YP_002383488.1 2431924 D 585054 CDS YP_002383489.1 218549698 7120943 2433018..2433518 1 NC_011740.1 converts methylaspartate to L-glutamate; methylaspartate mutase subunit S 2433518 7120943 EFER_2375 Escherichia fergusonii ATCC 35469 methylaspartate mutase subunit S YP_002383489.1 2433018 D 585054 CDS YP_002383490.1 218549699 7123943 2433518..2434906 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; glutamate mutase L 2434906 7123943 EFER_2376 Escherichia fergusonii ATCC 35469 glutamate mutase L YP_002383490.1 2433518 D 585054 CDS YP_002383491.1 218549700 7121891 2434925..2436370 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; methylaspartate mutase subunit E 2436370 7121891 EFER_2377 Escherichia fergusonii ATCC 35469 methylaspartate mutase subunit E YP_002383491.1 2434925 D 585054 CDS YP_002383492.1 218549701 7121892 2436371..2437612 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; methylaspartate ammonia-lyase 2437612 7121892 EFER_2378 Escherichia fergusonii ATCC 35469 methylaspartate ammonia-lyase YP_002383492.1 2436371 D 585054 CDS YP_002383493.1 218549702 7123944 2437616..2438986 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11748244; Product type pe : enzyme; 3-methylaspartate ammonia-lyase, glutamate mutase 2438986 7123944 EFER_2379 Escherichia fergusonii ATCC 35469 3-methylaspartate ammonia-lyase, glutamate mutase YP_002383493.1 2437616 D 585054 CDS YP_002383494.1 218549703 7121893 2438983..2439300 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2439300 7121893 EFER_2380 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383494.1 2438983 D 585054 CDS YP_002383495.1 218549704 7121894 2439360..2440724 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; symport protein 2440724 7121894 EFER_2381 Escherichia fergusonii ATCC 35469 symport protein YP_002383495.1 2439360 D 585054 CDS YP_002383496.1 218549705 7123945 2440787..2442439 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; Fumarate hydratase class I subunit beta 2442439 7123945 EFER_2382 Escherichia fergusonii ATCC 35469 Fumarate hydratase class I subunit beta YP_002383496.1 2440787 D 585054 CDS YP_002383497.1 218549706 7121895 complement(2442447..2443370) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; LysR-like transcriptional regulator 2443370 7121895 EFER_2383 Escherichia fergusonii ATCC 35469 LysR-like transcriptional regulator YP_002383497.1 2442447 R 585054 CDS YP_002383498.1 218549707 7123280 complement(2443702..2444571) 1 NC_011740.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 2444571 sucD 7123280 sucD Escherichia fergusonii ATCC 35469 succinyl-CoA synthetase subunit alpha YP_002383498.1 2443702 R 585054 CDS YP_002383499.1 218549708 7121957 complement(2444571..2445737) 1 NC_011740.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 2445737 sucC 7121957 sucC Escherichia fergusonii ATCC 35469 succinyl-CoA synthetase subunit beta YP_002383499.1 2444571 R 585054 CDS YP_002383500.1 218549709 7121955 complement(2445831..2447048) 1 NC_011740.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 2447048 sucB 7121955 sucB Escherichia fergusonii ATCC 35469 dihydrolipoamide succinyltransferase YP_002383500.1 2445831 R 585054 CDS YP_002383501.1 218549710 7123953 complement(2447063..2449864) 1 NC_011740.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 2449864 sucA 7123953 sucA Escherichia fergusonii ATCC 35469 2-oxoglutarate dehydrogenase E1 component YP_002383501.1 2447063 R 585054 CDS YP_002383502.1 218549711 7123402 complement(2450120..2450836) 1 NC_011740.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 2450836 sdhB 7123402 sdhB Escherichia fergusonii ATCC 35469 succinate dehydrogenase iron-sulfur subunit YP_002383502.1 2450120 R 585054 CDS YP_002383503.1 218549712 7121756 complement(2450852..2452618) 1 NC_011740.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 2452618 sdhA 7121756 sdhA Escherichia fergusonii ATCC 35469 succinate dehydrogenase flavoprotein subunit YP_002383503.1 2450852 R 585054 CDS YP_002383504.1 218549713 7123371 complement(2452618..2452965) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 82124790, 89076355, 9521736, 99414342, 6383359; Product type m : membrane component; succinate dehydrogenase cytochrome b556 small membrane subunit 2452965 sdhD 7123371 sdhD Escherichia fergusonii ATCC 35469 succinate dehydrogenase cytochrome b556 small membrane subunit YP_002383504.1 2452618 R 585054 CDS YP_002383505.1 218549714 7121758 complement(2452959..2453348) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6237244, 89076355, 89123360, 9521736, 99414342, 11259408, 3309132, 6383359, 9822661; Product type m : membrane component; succinate dehydrogenase cytochrome b556 large membrane subunit 2453348 sdhC 7121758 sdhC Escherichia fergusonii ATCC 35469 succinate dehydrogenase cytochrome b556 large membrane subunit YP_002383505.1 2452959 R 585054 CDS YP_002383506.1 218549715 7121757 2453400..2453621 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2453621 7121757 EFER_2392 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383506.1 2453400 D 585054 CDS YP_002383507.1 218549716 7123390 2453688..2453855 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2453855 7123390 EFER_2393 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383507.1 2453688 D 585054 CDS YP_002383508.1 218549717 7121897 2454057..2455340 1 NC_011740.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 2455340 gltA 7121897 gltA Escherichia fergusonii ATCC 35469 type II citrate synthase YP_002383508.1 2454057 D 585054 CDS YP_002383509.1 218549718 7120582 complement(2455493..2455651) 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 2455651 7120582 EFER_2395 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383509.1 2455493 R 585054 CDS YP_002383510.1 218549719 7121898 2455897..2456460 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; fimbrial-like adhesin protein 2456460 7121898 EFER_2396 Escherichia fergusonii ATCC 35469 fimbrial-like adhesin protein YP_002383510.1 2455897 D 585054 CDS YP_002383511.1 218549720 7123391 2456432..2458969 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2458969 ybgQ 7123391 ybgQ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383511.1 2456432 D 585054 CDS YP_002383512.1 218549721 7122083 2458960..2459715 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; protein, chaperone 2459715 7122083 EFER_2398 Escherichia fergusonii ATCC 35469 protein, chaperone YP_002383512.1 2458960 D 585054 CDS YP_002383513.1 218549722 7121899 2459712..2460773 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2460773 ybgO 7121899 ybgO Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383513.1 2459712 D 585054 CDS YP_002383514.1 218549723 7122082 2460847..2461968 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8002588; Product type ph : phenotype; hypothetical protein 2461968 abrB 7122082 abrB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383514.1 2460847 D 585054 CDS YP_002383515.1 218549724 7124008 complement(2462026..2462670) 1 NC_011740.1 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline; pyrrolidone-carboxylate peptidase 2462670 7124008 EFER_2401 Escherichia fergusonii ATCC 35469 pyrrolidone-carboxylate peptidase YP_002383515.1 2462026 R 585054 CDS YP_002383516.1 218549725 7123392 complement(2462680..2463675) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 2463675 7123392 EFER_2402 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383516.1 2462680 R 585054 CDS YP_002383517.1 218549726 7121905 complement(2463672..2464460) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 2464460 7121905 EFER_2403 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383517.1 2463672 R 585054 CDS YP_002383518.1 218549727 7121906 complement(2464469..2465203) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1729609; Product type pe : enzyme; LamB/YcsF family protein 2465203 ybgL 7121906 ybgL Escherichia fergusonii ATCC 35469 LamB/YcsF family protein YP_002383518.1 2464469 R 585054 CDS YP_002383519.1 218549728 7122081 complement(2465193..2466125) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hydrolase subunit 2466125 ybgK 7122081 ybgK Escherichia fergusonii ATCC 35469 hydrolase subunit YP_002383519.1 2465193 R 585054 CDS YP_002383520.1 218549729 7123423 complement(2466119..2466775) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hydrolase subunit 2466775 ybgJ 7123423 ybgJ Escherichia fergusonii ATCC 35469 hydrolase subunit YP_002383520.1 2466119 R 585054 CDS YP_002383521.1 218549730 7122080 complement(2466798..2467541) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14519207; hydrolase-oxidase 2467541 ybgI 7122080 ybgI Escherichia fergusonii ATCC 35469 hydrolase-oxidase YP_002383521.1 2466798 R 585054 CDS YP_002383522.1 218549731 7122079 2467810..2469291 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15175316; Product type pt : transporter; transporter 2469291 ybgH 7122079 ybgH Escherichia fergusonii ATCC 35469 transporter YP_002383522.1 2467810 D 585054 CDS YP_002383523.1 218549732 7122078 complement(2469334..2470752) 1 NC_011740.1 UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent; deoxyribodipyrimidine photolyase 2470752 phr 7122078 phr Escherichia fergusonii ATCC 35469 deoxyribodipyrimidine photolyase YP_002383523.1 2469334 R 585054 CDS YP_002383524.1 218549733 7122064 complement(2470749..2471258) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 6325460, 8387990; hypothetical protein 2471258 ybgA 7122064 ybgA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383524.1 2470749 R 585054 CDS YP_002383525.1 218549734 7122074 complement(2471360..2471566) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2471566 ybfA 7122074 ybfA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383525.1 2471360 R 585054 CDS YP_002383526.1 218549735 7123972 2471968..2473641 1 NC_011740.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A 2473641 kdpA 7123972 kdpA Escherichia fergusonii ATCC 35469 potassium-transporting ATPase subunit A YP_002383526.1 2471968 D 585054 CDS YP_002383527.1 218549736 7120805 2473664..2475712 1 NC_011740.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B 2475712 kdpB 7120805 kdpB Escherichia fergusonii ATCC 35469 potassium-transporting ATPase subunit B YP_002383527.1 2473664 D 585054 CDS YP_002383528.1 218549737 7123758 2475721..2476293 1 NC_011740.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C 2476293 kdpC 7123758 kdpC Escherichia fergusonii ATCC 35469 potassium-transporting ATPase subunit C YP_002383528.1 2475721 D 585054 CDS YP_002383529.1 218549738 7123223 2476286..2478970 1 NC_011740.1 sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein; sensor protein KdpD 2478970 kdpD 7123223 kdpD Escherichia fergusonii ATCC 35469 sensor protein KdpD YP_002383529.1 2476286 D 585054 CDS YP_002383530.1 218549739 7120806 2478967..2479644 1 NC_011740.1 response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport; DNA-binding transcriptional activator KdpE 2479644 kdpE 7120806 kdpE Escherichia fergusonii ATCC 35469 DNA-binding transcriptional activator KdpE YP_002383530.1 2478967 D 585054 CDS YP_002383531.1 218549740 7120807 complement(2479856..2480074) 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 2480074 7120807 EFER_2417 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383531.1 2479856 R 585054 CDS YP_002383532.1 218549741 7123393 2480334..2482532 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92041955; Product type e : enzyme; ornithine decarboxylase 2482532 speF 7123393 speF Escherichia fergusonii ATCC 35469 ornithine decarboxylase YP_002383532.1 2480334 D 585054 CDS YP_002383533.1 218549742 7121806 2482529..2483848 1 NC_011740.1 catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system; putrescine transporter 2483848 potE 7121806 potE Escherichia fergusonii ATCC 35469 putrescine transporter YP_002383533.1 2482529 D 585054 CDS YP_002383534.1 218549743 7120102 complement(2484071..2485711) 1 NC_011740.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 2485711 pgm 7120102 pgm Escherichia fergusonii ATCC 35469 phosphoglucomutase YP_002383534.1 2484071 R 585054 CDS YP_002383535.1 218549744 7122590 complement(2485737..2486282) 1 NC_011740.1 negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA 2486282 seqA 7122590 seqA Escherichia fergusonii ATCC 35469 replication initiation regulator SeqA YP_002383535.1 2485737 R 585054 CDS YP_002383536.1 218549745 7121768 2486467..2487231 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15808744; Product type pe : enzyme; hypothetical protein 2487231 ybfF 7121768 ybfF Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383536.1 2486467 D 585054 CDS YP_002383537.1 218549746 7122071 2487371..2487664 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20223640, 12427949; Product type cp : cell process; LexA regulated protein 2487664 ybfE 7122071 ybfE Escherichia fergusonii ATCC 35469 LexA regulated protein YP_002383537.1 2487371 D 585054 CDS YP_002383538.1 218549747 7123973 2487804..2488334 1 NC_011740.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA 2488334 fldA 7123973 fldA Escherichia fergusonii ATCC 35469 flavodoxin FldA YP_002383538.1 2487804 D 585054 CDS YP_002383539.1 218549748 7124135 complement(2488324..2488578) 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 2488578 7124135 EFER_2425 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383539.1 2488324 R 585054 CDS YP_002383540.1 218549749 7121907 2488623..2489069 1 NC_011740.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; ferric uptake regulator 2489069 fur 7121907 fur Escherichia fergusonii ATCC 35469 ferric uptake regulator YP_002383540.1 2488623 D 585054 CDS YP_002383541.1 218549750 7120156 complement(2489153..2489479) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; lipoprotein 2489479 ybfN 7120156 ybfN Escherichia fergusonii ATCC 35469 lipoprotein YP_002383541.1 2489153 R 585054 CDS YP_002383542.1 218549751 7122073 complement(2489529..2490935) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2118530, 9636669; Product type pt : transporter; outer membrane porin 2490935 ybfM 7122073 ybfM Escherichia fergusonii ATCC 35469 outer membrane porin YP_002383542.1 2489529 R 585054 CDS YP_002383543.1 218549752 7122072 complement(2491385..2493049) 1 NC_011740.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 2493049 glnS 7122072 glnS Escherichia fergusonii ATCC 35469 glutaminyl-tRNA synthetase YP_002383543.1 2491385 R 585054 CDS YP_002383544.1 218549753 7120202 complement(2493252..2495198) 1 NC_011740.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system N-acetyl glucosamine specific transporter subunit IIABC 2495198 nagE 7120202 nagE Escherichia fergusonii ATCC 35469 PTS system N-acetyl glucosamine specific transporter subunit IIABC YP_002383544.1 2493252 R 585054 CDS YP_002383545.1 218549754 7123733 2495531..2496331 1 NC_011740.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase 2496331 nagB 7123733 nagB Escherichia fergusonii ATCC 35469 glucosamine-6-phosphate deaminase YP_002383545.1 2495531 D 585054 CDS YP_002383546.1 218549755 7123731 2496392..2497540 1 NC_011740.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase 2497540 nagA 7123731 nagA Escherichia fergusonii ATCC 35469 N-acetylglucosamine-6-phosphate deacetylase YP_002383546.1 2496392 D 585054 CDS YP_002383547.1 218549756 7120662 2497549..2498769 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15066032, 90136533, 91171292, 92114782, 92356048, 2190615, 2668691, 7545108; Product type r : regulator; DNA-binding transcriptional dual regulator 2498769 nagC 7120662 nagC Escherichia fergusonii ATCC 35469 DNA-binding transcriptional dual regulator YP_002383547.1 2497549 D 585054 CDS YP_002383548.1 218549757 7123732 2498817..2499569 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16430214, 89343637; Product type e : enzyme; UMP phosphatase 2499569 nagD 7123732 nagD Escherichia fergusonii ATCC 35469 UMP phosphatase YP_002383548.1 2498817 D 585054 CDS YP_002383549.1 218549758 7120663 2499826..2501490 1 NC_011740.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B 2501490 asnB 7120663 asnB Escherichia fergusonii ATCC 35469 asparagine synthetase B YP_002383549.1 2499826 D 585054 CDS YP_002383550.1 218549759 7120568 complement(2501532..2501969) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2501969 7120568 EFER_2436 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383550.1 2501532 R 585054 CDS YP_002383551.1 218549760 7120043 2503194..2503778 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 2503778 7120043 EFER_2439 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383551.1 2503194 D 585054 CDS YP_002383552.1 218549761 7121909 complement(2503785..2504960) 1 NC_011740.1 catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 2504960 ubiF 7121909 ubiF Escherichia fergusonii ATCC 35469 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase YP_002383552.1 2503785 R 585054 CDS YP_002383553.1 218549762 7122620 2505106..2506530 1 NC_011740.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 2506530 miaB 7122620 miaB Escherichia fergusonii ATCC 35469 (dimethylallyl)adenosine tRNA methylthiotransferase YP_002383553.1 2505106 D 585054 CDS YP_002383554.1 218549763 7123243 2506644..2507723 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12762842; Product type pe : enzyme; hypothetical protein 2507723 ybeZ 7123243 ybeZ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383554.1 2506644 D 585054 CDS YP_002383555.1 218549764 7122070 2507720..2508187 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16511207; Product type pe : enzyme; metalloprotease 2508187 ybeY 7122070 ybeY Escherichia fergusonii ATCC 35469 metalloprotease YP_002383555.1 2507720 D 585054 CDS YP_002383556.1 218549765 7122069 2508277..2509155 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1779764; Product type pt : transporter; divalent ion export protein 2509155 ybeX 7122069 ybeX Escherichia fergusonii ATCC 35469 divalent ion export protein YP_002383556.1 2508277 D 585054 CDS YP_002383557.1 218549766 7122068 2509180..2510718 1 NC_011740.1 Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 2510718 lnt 7122068 lnt Escherichia fergusonii ATCC 35469 apolipoprotein N-acyltransferase YP_002383557.1 2509180 D 585054 CDS YP_002383558.1 218549767 7123762 complement(2510750..2510914) 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 2510914 7123762 EFER_2446 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383558.1 2510750 R 585054 CDS YP_002383559.1 218549768 7121910 complement(2510850..2512787) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2512787 7121910 EFER_2447 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383559.1 2510850 R 585054 CDS YP_002383560.1 218549769 7121911 2513183..2514091 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1091636, 1091635, 10493123, 8740179, 10972807; Product type t : transporter; glutamate and aspartate transporter subunit 2514091 gltI 7121911 gltI Escherichia fergusonii ATCC 35469 glutamate and aspartate transporter subunit YP_002383560.1 2513183 D 585054 CDS YP_002383561.1 218549770 7120584 2514261..2515001 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11121068; Product type t : transporter; glutamate and aspartate ABC transporter membrane protein 2515001 gltJ 7120584 gltJ Escherichia fergusonii ATCC 35469 glutamate and aspartate ABC transporter membrane protein YP_002383561.1 2514261 D 585054 CDS YP_002383562.1 218549771 7123721 2515001..2515675 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11121068; Product type t : transporter; glutamate and aspartate ABC transporter membrane protein 2515675 gltK 7123721 gltK Escherichia fergusonii ATCC 35469 glutamate and aspartate ABC transporter membrane protein YP_002383562.1 2515001 D 585054 CDS YP_002383563.1 218549772 7120585 2515675..2516400 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11121068; Product type t : transporter; glutamate and aspartate ABC transporter ATP-binding protein 2516400 gltL 7120585 gltL Escherichia fergusonii ATCC 35469 glutamate and aspartate ABC transporter ATP-binding protein YP_002383563.1 2515675 D 585054 CDS YP_002383564.1 218549773 7120586 2516518..2517453 1 NC_011740.1 Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific; ribonucleoside hydrolase 1 2517453 rihA 7120586 rihA Escherichia fergusonii ATCC 35469 ribonucleoside hydrolase 1 YP_002383564.1 2516518 D 585054 CDS YP_002383565.1 218549774 7123862 2517537..2519207 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12183460, 14734171, 22055095, 9735342; Product type f : factor; Hsp70 family chaperone Hsc62, binds to RpoD and inhibits transcription 2519207 hscC 7123862 hscC Escherichia fergusonii ATCC 35469 Hsp70 family chaperone Hsc62, binds to RpoD and inhibits transcription YP_002383565.1 2517537 D 585054 CDS YP_002383566.1 218549775 7122223 complement(2519267..2520718) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12183460, 12054669; Product type f : factor; Hsc56 co-chaperone of HscC 2520718 djlC 7122223 djlC Escherichia fergusonii ATCC 35469 Hsc56 co-chaperone of HscC YP_002383566.1 2519267 R 585054 CDS YP_002383567.1 218549776 7124122 complement(2520715..2521422) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2521422 ybeU 7124122 ybeU Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383567.1 2520715 R 585054 CDS YP_002383568.1 218549777 7122067 2521524..2522078 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2522078 ybeT 7122067 ybeT Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383568.1 2521524 D 585054 CDS YP_002383569.1 218549778 7122902 complement(2523002..2523868) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type h : extrachromosomal origin; IS3 element protein InsF 2523868 insF 7122902 insF Escherichia fergusonii ATCC 35469 IS3 element protein InsF YP_002383569.1 2523002 R 585054 CDS YP_002383570.1 218549779 7120742 complement(2523865..2524173) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type h : extrachromosomal origin; IS3 element protein InsE 2524173 insE 7120742 insE Escherichia fergusonii ATCC 35469 IS3 element protein InsE YP_002383570.1 2523865 R 585054 CDS YP_002383571.1 218549780 7122903 complement(2524774..2525481) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2525481 ybeR 7122903 ybeR Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383571.1 2524774 R 585054 CDS YP_002383572.1 218549781 7122066 2525645..2526622 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2526622 ybeQ 7122066 ybeQ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383572.1 2525645 D 585054 CDS YP_002383573.1 218549782 7122065 complement(2526692..2527174) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11373298, 12105207, 3320963, 7567469; hypothetical protein 2527174 ybeL 7122065 ybeL Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383573.1 2526692 R 585054 CDS YP_002383574.1 218549783 7122063 2527409..2529991 1 NC_011740.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 2529991 leuS 7122063 leuS Escherichia fergusonii ATCC 35469 leucyl-tRNA synthetase YP_002383574.1 2527409 D 585054 CDS YP_002383575.1 218549784 7120828 2530006..2530587 1 NC_011740.1 rare lipoprotein B; involved in the assembly of LPS in the outer membrane; LPS-assembly lipoprotein RlpB 2530587 rlpB 7120828 rlpB Escherichia fergusonii ATCC 35469 LPS-assembly lipoprotein RlpB YP_002383575.1 2530006 D 585054 CDS YP_002383576.1 218549785 7121416 2530587..2531618 1 NC_011740.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 2531618 holA 7121416 holA Escherichia fergusonii ATCC 35469 DNA polymerase III subunit delta YP_002383576.1 2530587 D 585054 CDS YP_002383577.1 218549786 7122208 2531622..2532263 1 NC_011740.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 2532263 nadD 7122208 nadD Escherichia fergusonii ATCC 35469 nicotinic acid mononucleotide adenylyltransferase YP_002383577.1 2531622 D 585054 CDS YP_002383578.1 218549787 7120660 2532522..2532839 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2532839 ybeB 7120660 ybeB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383578.1 2532522 D 585054 CDS YP_002383579.1 218549788 7121099 2532843..2533310 1 NC_011740.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 2533310 ybeA 7121099 ybeA Escherichia fergusonii ATCC 35469 rRNA large subunit methyltransferase YP_002383579.1 2532843 D 585054 CDS YP_002383580.1 218549789 7121098 2533341..2535242 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86196149, 87030266, 89174517, 2644207; Product type e : enzyme; penicillin-binding protein 2 2535242 mrdA 7121098 mrdA Escherichia fergusonii ATCC 35469 penicillin-binding protein 2 YP_002383580.1 2533341 D 585054 CDS YP_002383581.1 218549790 7120965 2535245..2536357 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89123070, 90036736, 91072213, 3316191; Product type cp : cell process; cell wall shape-determining protein 2536357 mrdB 7120965 mrdB Escherichia fergusonii ATCC 35469 cell wall shape-determining protein YP_002383581.1 2535245 D 585054 CDS YP_002383582.1 218549791 7123250 2536308..2537456 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88058785, 2644207; Product type lp : lipoprotein; rare lipoprotein A 2537456 rlpA 7123250 rlpA Escherichia fergusonii ATCC 35469 rare lipoprotein A YP_002383582.1 2536308 D 585054 CDS YP_002383583.1 218549792 7121415 2537597..2538808 1 NC_011740.1 penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; D-alanyl-D-alanine carboxypeptidase 2538808 dacA 7121415 dacA Escherichia fergusonii ATCC 35469 D-alanyl-D-alanine carboxypeptidase YP_002383583.1 2537597 D 585054 CDS YP_002383584.1 218549793 7122860 2538914..2539177 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8444795; hypothetical protein 2539177 ybeD 7122860 ybeD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383584.1 2538914 D 585054 CDS YP_002383585.1 218549794 7123807 2539278..2539928 1 NC_011740.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 2539928 lipB 7123807 lipB Escherichia fergusonii ATCC 35469 lipoate-protein ligase B YP_002383585.1 2539278 D 585054 CDS YP_002383586.1 218549795 7120835 2540107..2541072 1 NC_011740.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 2541072 lipA 7120835 lipA Escherichia fergusonii ATCC 35469 lipoyl synthase YP_002383586.1 2540107 D 585054 CDS YP_002383587.1 218549796 7123761 complement(2541186..2541404) 1 NC_011740.1 TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein E 2541404 tatE 7123761 tatE Escherichia fergusonii ATCC 35469 twin arginine translocase protein E YP_002383587.1 2541186 R 585054 CDS YP_002383588.1 218549797 7123957 complement(2541518..2542381) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hydrolase 2542381 7123957 EFER_2478 Escherichia fergusonii ATCC 35469 hydrolase YP_002383588.1 2541518 R 585054 CDS YP_002383589.1 218549798 7123394 2542398..2542781 1 NC_011740.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 2542781 crcB 7123394 crcB Escherichia fergusonii ATCC 35469 camphor resistance protein CrcB YP_002383589.1 2542398 D 585054 CDS YP_002383590.1 218549799 7122801 complement(2542835..2543044) 1 NC_011740.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator; cold shock protein CspE 2543044 cspE 7122801 cspE Escherichia fergusonii ATCC 35469 cold shock protein CspE YP_002383590.1 2542835 R 585054 CDS YP_002383591.1 218549800 7122821 complement(2543230..2543814) 1 NC_011740.1 catalyzes the transfer of palmitate to lipid A; palmitoyl transferase 2543814 pagP 7122821 pagP Escherichia fergusonii ATCC 35469 palmitoyl transferase YP_002383591.1 2543230 R 585054 CDS YP_002383592.1 218549801 7121912 2544237..2545625 1 NC_011740.1 responsible for the transport of C4-dicarboxylates during anaerobic growth; C4-dicarboxylate transporter DcuC 2545625 dcuC 7121912 dcuC Escherichia fergusonii ATCC 35469 C4-dicarboxylate transporter DcuC YP_002383592.1 2544237 D 585054 CDS YP_002383593.1 218549802 7122877 2545854..2546666 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90151658, 90264307, 2253883, 8188249; Product type e : enzyme; ribonuclease I 2546666 rna 7122877 rna Escherichia fergusonii ATCC 35469 ribonuclease I YP_002383593.1 2545854 D 585054 CDS YP_002383594.1 218549803 7121421 2546865..2547275 1 NC_011740.1 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator 2547275 rnk 7121421 rnk Escherichia fergusonii ATCC 35469 nucleoside diphosphate kinase regulator YP_002383594.1 2546865 D 585054 CDS YP_002383595.1 218549804 7121429 2547634..2548062 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12732303, 12071968; Product type f : factor; universal stress protein UP12 2548062 uspG 7121429 uspG Escherichia fergusonii ATCC 35469 universal stress protein UP12 YP_002383595.1 2547634 D 585054 CDS YP_002383596.1 218549805 7122644 complement(2548184..2549749) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89197774, 1592833; Product type e : enzyme; alkyl hydroperoxide reductase F52a subunit 2549749 ahpF 7122644 ahpF Escherichia fergusonii ATCC 35469 alkyl hydroperoxide reductase F52a subunit YP_002383596.1 2548184 R 585054 CDS YP_002383597.1 218549806 7124014 complement(2549920..2550483) 1 NC_011740.1 with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate; alkyl hydroperoxide reductase subunit C 2550483 ahpC 7124014 ahpC Escherichia fergusonii ATCC 35469 alkyl hydroperoxide reductase subunit C YP_002383597.1 2549920 R 585054 CDS YP_002383598.1 218549807 7124013 2550796..2551602 1 NC_011740.1 Involved in disulfide bond formation; disulfide isomerase/thiol-disulfide oxidase 2551602 dsbG 7124013 dsbG Escherichia fergusonii ATCC 35469 disulfide isomerase/thiol-disulfide oxidase YP_002383598.1 2550796 D 585054 CDS YP_002383599.1 218549808 7122923 2551769..2552740 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; HTH-type transcriptional regulator ybdO 2552740 7122923 EFER_2490 Escherichia fergusonii ATCC 35469 HTH-type transcriptional regulator ybdO YP_002383599.1 2551769 D 585054 CDS YP_002383600.1 218549809 7121913 2552809..2554059 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 12057959; Product type r : regulator; immunoglobulin-binding regulator 2554059 ibrA 7121913 ibrA Escherichia fergusonii ATCC 35469 immunoglobulin-binding regulator YP_002383600.1 2552809 D 585054 CDS YP_002383601.1 218549810 7120720 2554056..2554673 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 12057959; Product type r : regulator; immunoglobulin-binding regulator 2554673 ibrB 7120720 ibrB Escherichia fergusonii ATCC 35469 immunoglobulin-binding regulator YP_002383601.1 2554056 D 585054 CDS YP_002383602.1 218549811 7120721 complement(2554674..2555834) 1 NC_011740.1 catalyzes the transfer of an amino moiety; aminotransferase 2555834 ybdL 7120721 ybdL Escherichia fergusonii ATCC 35469 aminotransferase YP_002383602.1 2554674 R 585054 CDS YP_002383603.1 218549812 7121097 2555943..2557031 1 NC_011740.1 member of the iron-containing alcohol dehydrogenase family; unknown function; hypothetical protein 2557031 ybdH 7121097 ybdH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383603.1 2555943 D 585054 CDS YP_002383604.1 218549813 7121095 complement(2557041..2557238) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2557238 ybdD 7121095 ybdD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383604.1 2557041 R 585054 CDS YP_002383605.1 218549814 7121092 complement(2557366..2559471) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91162636, 2521622; Product type pf : factor; carbon starvation protein 2559471 cstA 7121092 cstA Escherichia fergusonii ATCC 35469 carbon starvation protein YP_002383605.1 2557366 R 585054 CDS YP_002383606.1 218549815 7124109 complement(2559652..2560065) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2521621, 2521622, 15808744; Product type pe : enzyme; hypothetical protein 2560065 ybdB 7124109 ybdB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383606.1 2559652 R 585054 CDS YP_002383607.1 218549816 7121091 complement(2560068..2560814) 1 NC_011740.1 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase 2560814 entA 7121091 entA Escherichia fergusonii ATCC 35469 2,3-dihydroxybenzoate-2,3-dehydrogenase YP_002383607.1 2560068 R 585054 CDS YP_002383608.1 218549817 7122950 complement(2560814..2561671) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20183918, 90241937, 91035252, 9485415, 97361959, 2521621, 2521622; Product type e : enzyme; isochorismatase 2561671 entB 7122950 entB Escherichia fergusonii ATCC 35469 isochorismatase YP_002383608.1 2560814 R 585054 CDS YP_002383609.1 218549818 7122951 complement(2561685..2563295) 1 NC_011740.1 bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E 2563295 entE 7122951 entE Escherichia fergusonii ATCC 35469 enterobactin synthase subunit E YP_002383609.1 2561685 R 585054 CDS YP_002383610.1 218549819 7122952 complement(2563305..2564480) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89123153, 90165423, 90241936, 2110093, 2139473; Product type e : enzyme; isochorismate synthase 1 2564480 entC 7122952 entC Escherichia fergusonii ATCC 35469 isochorismate synthase 1 YP_002383610.1 2563305 R 585054 CDS YP_002383611.1 218549820 7123561 2564669..2565625 1 NC_011740.1 with FepCDG is involved in the transport of ferric enterobactin; iron-enterobactin transporter periplasmic binding protein 2565625 fepB 7123561 fepB Escherichia fergusonii ATCC 35469 iron-enterobactin transporter periplasmic binding protein YP_002383611.1 2564669 D 585054 CDS YP_002383612.1 218549821 7120006 complement(2565629..2566879) 1 NC_011740.1 protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters; enterobactin exporter EntS 2566879 ybdA 7120006 ybdA Escherichia fergusonii ATCC 35469 enterobactin exporter EntS YP_002383612.1 2565629 R 585054 CDS YP_002383613.1 218549822 7121090 2566990..2567994 1 NC_011740.1 with FepBCG is involved in the transport of ferric enterobactin; iron-enterobactin transporter membrane protein 2567994 fepD 7121090 fepD Escherichia fergusonii ATCC 35469 iron-enterobactin transporter membrane protein YP_002383613.1 2566990 D 585054 CDS YP_002383614.1 218549823 7123088 2567991..2568983 1 NC_011740.1 with FepBCD is involved in the transport of ferric enterobactin; iron-enterobactin transporter permease 2568983 fepG 7123088 fepG Escherichia fergusonii ATCC 35469 iron-enterobactin transporter permease YP_002383614.1 2567991 D 585054 CDS YP_002383615.1 218549824 7120007 2568662..2569780 1 NC_011740.1 with FepBDE is involved in the transport of ferric enterobactin; iron-enterobactin transporter ATP-binding protein 2569780 fepC 7120007 fepC Escherichia fergusonii ATCC 35469 iron-enterobactin transporter ATP-binding protein YP_002383615.1 2568662 D 585054 CDS YP_002383616.1 218549825 7123087 complement(2569815..2570990) 1 NC_011740.1 part of the ferric enterobactin transport system; necessary for enetrobactin uptake; ferric enterobactin transport protein FepE 2570990 7123087 EFER_2507 Escherichia fergusonii ATCC 35469 ferric enterobactin transport protein FepE YP_002383616.1 2569815 R 585054 CDS YP_002383617.1 218549826 7123395 complement(2571200..2575081) 1 NC_011740.1 with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin; enterobactin synthase subunit F 2575081 entF 7123395 entF Escherichia fergusonii ATCC 35469 enterobactin synthase subunit F YP_002383617.1 2571200 R 585054 CDS YP_002383618.1 218549827 7124133 complement(2575078..2575302) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2575302 ybdZ 7124133 ybdZ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383618.1 2575078 R 585054 CDS YP_002383619.1 218549828 7123806 complement(2575299..2576423) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92291125, 94198561, 2974033; Product type e : enzyme; enterobactin/ferric enterobactin esterase 2576423 fes 7123806 fes Escherichia fergusonii ATCC 35469 enterobactin/ferric enterobactin esterase YP_002383619.1 2575299 R 585054 CDS YP_002383620.1 218549829 7120008 2576744..2578984 1 NC_011740.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA 2578984 fepA 7120008 fepA Escherichia fergusonii ATCC 35469 outer membrane receptor FepA YP_002383620.1 2576744 D 585054 CDS YP_002383621.1 218549830 7123361 2579009..2579818 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 89313305, 90132534, 91035252, 8939709, 9214294; Product type e : enzyme; enterobactin synthase multienzyme complex phosphopantetheinyltransferase 2579818 7123361 EFER_2513 Escherichia fergusonii ATCC 35469 enterobactin synthase multienzyme complex phosphopantetheinyltransferase YP_002383621.1 2579009 D 585054 CDS YP_002383622.1 218549831 7121914 complement(2579820..2580866) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transketolase 2580866 7121914 EFER_2514 Escherichia fergusonii ATCC 35469 transketolase YP_002383622.1 2579820 R 585054 CDS YP_002383623.1 218549832 7121915 complement(2580748..2581578) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 93374831, 8396116; Product type e : enzyme; transketolase N-terminal section (TK) 2581578 7121915 EFER_2515 Escherichia fergusonii ATCC 35469 transketolase N-terminal section (TK) YP_002383623.1 2580748 R 585054 CDS YP_002383624.1 218549833 7123396 2581941..2582891 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator 2582891 7123396 EFER_2516 Escherichia fergusonii ATCC 35469 transcriptional regulator YP_002383624.1 2581941 D 585054 CDS YP_002383625.1 218549834 7121916 2583242..2584762 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; glycerol kinase 2 2584762 7121916 EFER_2517 Escherichia fergusonii ATCC 35469 glycerol kinase 2 YP_002383625.1 2583242 D 585054 CDS YP_002383626.1 218549835 7121917 2584866..2585801 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; sugar ABC transporter substrate-binding protein 2585801 7121917 EFER_2518 Escherichia fergusonii ATCC 35469 sugar ABC transporter substrate-binding protein YP_002383626.1 2584866 D 585054 CDS YP_002383627.1 218549836 7121918 2585812..2586468 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; lipoprotein 2586468 7121918 EFER_2519 Escherichia fergusonii ATCC 35469 lipoprotein YP_002383627.1 2585812 D 585054 CDS YP_002383628.1 218549837 7121919 2586470..2588014 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type t : transporter; transport system ATP-binding protein 2588014 7121919 EFER_2520 Escherichia fergusonii ATCC 35469 transport system ATP-binding protein YP_002383628.1 2586470 D 585054 CDS YP_002383629.1 218549838 7121920 2588032..2589099 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transport system permease 2589099 7121920 EFER_2521 Escherichia fergusonii ATCC 35469 transport system permease YP_002383629.1 2588032 D 585054 CDS YP_002383630.1 218549839 7121921 2589126..2589950 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; oxidoreductase 2589950 7121921 EFER_2522 Escherichia fergusonii ATCC 35469 oxidoreductase YP_002383630.1 2589126 D 585054 CDS YP_002383631.1 218549840 7121922 2589950..2590768 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; short chain dehydrogenase 2590768 7121922 EFER_2523 Escherichia fergusonii ATCC 35469 short chain dehydrogenase YP_002383631.1 2589950 D 585054 CDS YP_002383632.1 218549841 7123948 complement(2590942..2591175) 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 2591175 7123948 EFER_2524 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383632.1 2590942 R 585054 CDS YP_002383633.1 218549842 7123397 complement(2591381..2591632) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10361310; Product type pm : membrane component; small toxic membrane polypeptide, HokE-like protein (partial) 2591632 7123397 EFER_2525 Escherichia fergusonii ATCC 35469 small toxic membrane polypeptide, HokE-like protein (partial) YP_002383633.1 2591381 R 585054 CDS YP_002383634.1 218549843 7121923 complement(2591445..2591678) 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 2591678 7121923 EFER_2526 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383634.1 2591445 R 585054 CDS YP_002383635.1 218549844 7121924 2591985..2593103 1 NC_011740.1 ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity; carboxylate-amine ligase 2593103 ybdK 7121924 ybdK Escherichia fergusonii ATCC 35469 carboxylate-amine ligase YP_002383635.1 2591985 D 585054 CDS YP_002383636.1 218549845 7121096 2593169..2593417 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2593417 ybdJ 7121096 ybdJ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383636.1 2593169 D 585054 CDS YP_002383637.1 218549846 7123805 2593482..2593850 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2593850 ybdF 7123805 ybdF Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383637.1 2593482 D 585054 CDS YP_002383638.1 218549847 7121093 2593945..2594598 1 NC_011740.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase 2594598 nfnB 7121093 nfnB Escherichia fergusonii ATCC 35469 dihydropteridine reductase YP_002383638.1 2593945 D 585054 CDS YP_002383639.1 218549848 7120686 2594706..2595953 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; membrane protein 2595953 ybdG 7120686 ybdG Escherichia fergusonii ATCC 35469 membrane protein YP_002383639.1 2594706 D 585054 CDS YP_002383640.1 218549849 7121094 complement(2596033..2597409) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91267923, 94042931, 8626334; Product type t : transporter; phenylalanine transporter 2597409 pheP 7121094 pheP Escherichia fergusonii ATCC 35469 phenylalanine transporter YP_002383640.1 2596033 R 585054 CDS YP_002383641.1 218549850 7122594 complement(2597511..2600654) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20461235, 21125583, 21178899, 21450803, 11399769, 12813074, 1711024, 7984428; Product type t : transporter; copper/silver efflux system, membrane component 2600654 cusA 7122594 cusA Escherichia fergusonii ATCC 35469 copper/silver efflux system, membrane component YP_002383641.1 2597511 R 585054 CDS YP_002383642.1 218549851 7124110 complement(2600557..2600712) 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 2600712 7124110 EFER_2535 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383642.1 2600557 R 585054 CDS YP_002383643.1 218549852 7123398 complement(2600666..2601889) 1 NC_011740.1 with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB 2601889 cusB 7123398 cusB Escherichia fergusonii ATCC 35469 copper/silver efflux system membrane fusion protein CusB YP_002383643.1 2600666 R 585054 CDS YP_002383644.1 218549853 7122828 complement(2601905..2602237) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 21125583, 11283292, 11399769, 12813074; Product type f : factor; copper-binding protein 2602237 cusF 7122828 cusF Escherichia fergusonii ATCC 35469 copper-binding protein YP_002383644.1 2601905 R 585054 CDS YP_002383645.1 218549854 7124111 complement(2602260..2603648) 1 NC_011740.1 with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC 2603648 cusC 7124111 cusC Escherichia fergusonii ATCC 35469 copper/silver efflux system outer membrane protein CusC YP_002383645.1 2602260 R 585054 CDS YP_002383646.1 218549855 7122829 2603799..2604482 1 NC_011740.1 response regulator in two-component regulatory system with CusS; regulates the copper efflux system; DNA-binding transcriptional activator CusR 2604482 cusR 7122829 cusR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional activator CusR YP_002383646.1 2603799 D 585054 CDS YP_002383647.1 218549856 7122830 2604460..2605920 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20461235, 11283292, 11399769; Product type r : regulator; sensor kinase CusS 2605920 cusS 7122830 cusS Escherichia fergusonii ATCC 35469 sensor kinase CusS YP_002383647.1 2604460 D 585054 CDS YP_002383648.1 218549857 7122831 2606136..2606615 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2606615 7122831 EFER_2542 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383648.1 2606136 D 585054 CDS YP_002383649.1 218549858 7121925 2606809..2607099 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 2607099 7121925 EFER_2543 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383649.1 2606809 D 585054 CDS YP_002383650.1 218549859 7121926 complement(2607657..2609531) 1 NC_011740.1 molecular chaperone; heat shock protein 90 2609531 htpG 7121926 htpG Escherichia fergusonii ATCC 35469 heat shock protein 90 YP_002383650.1 2607657 R 585054 CDS YP_002383651.1 218549860 7122231 complement(2609641..2610246) 1 NC_011740.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 2610246 recR 7122231 recR Escherichia fergusonii ATCC 35469 recombination protein RecR YP_002383651.1 2609641 R 585054 CDS YP_002383652.1 218549861 7121384 complement(2610246..2610575) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 15322138, 1698765, 2674903; hypothetical protein 2610575 ybaB 7121384 ybaB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383652.1 2610246 R 585054 CDS YP_002383653.1 218549862 7121064 complement(2610628..2612559) 1 NC_011740.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 2612559 dnaX 7121064 dnaX Escherichia fergusonii ATCC 35469 DNA polymerase III subunits gamma and tau YP_002383653.1 2610628 R 585054 CDS YP_002383654.1 218549863 7124126 complement(2612688..2613239) 1 NC_011740.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 2613239 apt 7124126 apt Escherichia fergusonii ATCC 35469 adenine phosphoribosyltransferase YP_002383654.1 2612688 R 585054 CDS YP_002383655.1 218549864 7120525 complement(2613401..2613769) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2613769 ybaN 7120525 ybaN Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383655.1 2613401 R 585054 CDS YP_002383656.1 218549865 7123261 2613839..2614366 1 NC_011740.1 PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks; primosomal replication protein N'' 2614366 priC 7123261 priC Escherichia fergusonii ATCC 35469 primosomal replication protein N'' YP_002383656.1 2613839 D 585054 CDS YP_002383657.1 218549866 7120127 2614380..2614544 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2614544 ybaM 7120127 ybaM Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383657.1 2614380 D 585054 CDS YP_002383658.1 218549867 7121067 complement(2614583..2617942) 1 NC_011740.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA 2617942 kefA 7121067 kefA Escherichia fergusonii ATCC 35469 potassium efflux protein KefA YP_002383658.1 2614583 R 585054 CDS YP_002383659.1 218549868 7120811 complement(2618068..2618715) 1 NC_011740.1 regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine; DNA-binding transcriptional repressor AcrR 2618715 acrR 7120811 acrR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional repressor AcrR YP_002383659.1 2618068 R 585054 CDS YP_002383660.1 218549869 7122270 2618859..2620052 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15155734, 21450803, 383699, 390095, 94012493, 10920254, 7651136; Product type t : transporter; multidrug efflux system 2620052 acrA 7122270 acrA Escherichia fergusonii ATCC 35469 multidrug efflux system YP_002383660.1 2618859 D 585054 CDS YP_002383661.1 218549870 7122265 2620075..2623224 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12351840, 12654283, 15111118, 15155734, 21450803, 94012493, 10920254, 7651136; Product type t : transporter; multidrug efflux system protein 2623224 acrB 7122265 acrB Escherichia fergusonii ATCC 35469 multidrug efflux system protein YP_002383661.1 2620075 D 585054 CDS YP_002383662.1 218549871 7122266 2623727..2624101 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1956303, 7984428, 14645275; hypothetical protein 2624101 ybaJ 7122266 ybaJ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383662.1 2623727 D 585054 CDS YP_002383663.1 218549872 7121065 2624128..2624346 1 NC_011740.1 with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins; hemolysin expression-modulating protein 2624346 hha 7121065 hha Escherichia fergusonii ATCC 35469 hemolysin expression-modulating protein YP_002383663.1 2624128 D 585054 CDS YP_002383664.1 218549873 7122193 2624819..2625313 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2625313 ylaC 7122193 ylaC Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383664.1 2624819 D 585054 CDS YP_002383665.1 218549874 7122042 2625452..2627002 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2627002 7122042 EFER_2559 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383665.1 2625452 D 585054 CDS YP_002383666.1 218549875 7121927 complement(2627044..2627397) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2627397 ybaA 7121927 ybaA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383666.1 2627044 R 585054 CDS YP_002383667.1 218549876 7120010 complement(2627545..2627727) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2627727 7120010 EFER_2561 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383667.1 2627545 R 585054 CDS YP_002383668.1 218549877 7121928 2627698..2628087 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; methylated DNA-protein cysteine alkyltransferase 2628087 ybaZ 7121928 ybaZ Escherichia fergusonii ATCC 35469 methylated DNA-protein cysteine alkyltransferase YP_002383668.1 2627698 D 585054 CDS YP_002383669.1 218549878 7121074 2628188..2629516 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; IS4 transposase; KpLE2 phage-like element 2629516 insG 7121074 insG Escherichia fergusonii ATCC 35469 IS4 transposase; KpLE2 phage-like element YP_002383669.1 2628188 D 585054 CDS YP_002383670.1 218549879 7120745 complement(2629556..2630128) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; lipoprotein 2630128 ybaY 7120745 ybaY Escherichia fergusonii ATCC 35469 lipoprotein YP_002383670.1 2629556 R 585054 CDS YP_002383671.1 218549880 7121073 2630346..2631206 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86139906, 91250410, 10876240; Product type e : enzyme; acyl-CoA thioesterase II 2631206 tesB 7121073 tesB Escherichia fergusonii ATCC 35469 acyl-CoA thioesterase II YP_002383671.1 2630346 D 585054 CDS YP_002383672.1 218549881 7121986 complement(2631255..2632541) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 22020597, 9618533, 10931328, 1645722, 7984428; Product type t : transporter; ammonium transporter 2632541 amtB 7121986 amtB Escherichia fergusonii ATCC 35469 ammonium transporter YP_002383672.1 2631255 R 585054 CDS YP_002383673.1 218549882 7123712 complement(2632571..2632909) 1 NC_011740.1 indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia.; nitrogen regulatory protein P-II 2 2632909 glnK 7123712 glnK Escherichia fergusonii ATCC 35469 nitrogen regulatory protein P-II 2 YP_002383673.1 2632571 R 585054 CDS YP_002383674.1 218549883 7120198 complement(2633090..2634871) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 94124004; Product type pt : transporter; multidrug transporter membrane protein/ATP-binding protein 2634871 mdlB 7120198 mdlB Escherichia fergusonii ATCC 35469 multidrug transporter membrane protein/ATP-binding protein YP_002383674.1 2633090 R 585054 CDS YP_002383675.1 218549884 7121242 complement(2634864..2636636) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 94124004, 10850996; Product type pt : transporter; multidrug transporter membrane protein/ATP-binding protein 2636636 mdlA 7121242 mdlA Escherichia fergusonii ATCC 35469 multidrug transporter membrane protein/ATP-binding protein YP_002383675.1 2634864 R 585054 CDS YP_002383676.1 218549885 7121241 complement(2636666..2637124) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7904973, 10850996; Product type pr : regulator; DNA-binding transcriptional regulator 2637124 ybaO 7121241 ybaO Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YP_002383676.1 2636666 R 585054 CDS YP_002383677.1 218549886 7121068 complement(2637277..2638095) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15292217; Product type e : enzyme; thiamin pyrimidine pyrophosphate hydrolase 2638095 cof 7121068 cof Escherichia fergusonii ATCC 35469 thiamin pyrimidine pyrophosphate hydrolase YP_002383677.1 2637277 R 585054 CDS YP_002383678.1 218549887 7122792 2638195..2639895 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2639895 ybaE 7122792 ybaE Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383678.1 2638195 D 585054 CDS YP_002383679.1 218549888 7123260 2639960..2640655 1 NC_011740.1 YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His; queuosine biosynthesis protein QueC 2640655 queC 7123260 queC Escherichia fergusonii ATCC 35469 queuosine biosynthesis protein QueC YP_002383679.1 2639960 D 585054 CDS YP_002383680.1 218549889 7122342 complement(2640707..2641105) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2641105 ybaW 7122342 ybaW Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383680.1 2640707 R 585054 CDS YP_002383681.1 218549890 7121072 complement(2641211..2641654) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2641654 ybaV 7121072 ybaV Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383681.1 2641211 R 585054 CDS YP_002383682.1 218549891 7123263 complement(2641735..2643651) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9670013; Product type e : enzyme; peptidyl-prolyl cis-trans isomerase 2643651 ppiD 7123263 ppiD Escherichia fergusonii ATCC 35469 peptidyl-prolyl cis-trans isomerase YP_002383682.1 2641735 R 585054 CDS YP_002383683.1 218549892 7120114 complement(2643798..2644070) 1 NC_011740.1 histone-like DNA-binding protein; transcriptional regulator HU subunit beta 2644070 hupB 7120114 hupB Escherichia fergusonii ATCC 35469 transcriptional regulator HU subunit beta YP_002383683.1 2643798 R 585054 CDS YP_002383684.1 218549893 7124004 complement(2644280..2646634) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10094703, 14665623, 8939438, 91072263, 97137085, 2984174, 3042779, 3289547, 7988699, 8226758, 8294008; Product type e : enzyme; DNA-binding ATP-dependent protease La 2646634 lon 7124004 lon Escherichia fergusonii ATCC 35469 DNA-binding ATP-dependent protease La YP_002383684.1 2644280 R 585054 CDS YP_002383685.1 218549894 7123381 complement(2646821..2648095) 1 NC_011740.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 2648095 clpX 7123381 clpX Escherichia fergusonii ATCC 35469 ATP-dependent protease ATP-binding subunit ClpX YP_002383685.1 2646821 R 585054 CDS YP_002383686.1 218549895 7120904 complement(2648221..2648844) 1 NC_011740.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 2648844 clpP 7120904 clpP Escherichia fergusonii ATCC 35469 ATP-dependent Clp protease proteolytic subunit YP_002383686.1 2648221 R 585054 CDS YP_002383687.1 218549896 7120903 complement(2649089..2650387) 1 NC_011740.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 2650387 tig 7120903 tig Escherichia fergusonii ATCC 35469 trigger factor YP_002383687.1 2649089 R 585054 CDS YP_002383688.1 218549897 7122132 complement(2650728..2651045) 1 NC_011740.1 positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress; transcriptional regulator BolA 2651045 bolA 7122132 bolA Escherichia fergusonii ATCC 35469 transcriptional regulator BolA YP_002383688.1 2650728 R 585054 CDS YP_002383689.1 218549898 7121676 2651348..2651926 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; hypothetical protein 2651926 yajG 7121676 yajG Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383689.1 2651348 D 585054 CDS YP_002383690.1 218549899 7121059 2651970..2653445 1 NC_011740.1 in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; muropeptide transporter 2653445 ampG 7121059 ampG Escherichia fergusonii ATCC 35469 muropeptide transporter YP_002383690.1 2651970 D 585054 CDS YP_002383691.1 218549900 7120514 2654088..2655035 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92112945, 92371427, 9378722, 98021084, 11017202, 1322173, 2162835, 2162837, 2165491, 2168206, 8231804, 8618822; Product type c : carrier; cytochrome o ubiquinol oxidase subunit II 2655035 cyoA 7120514 cyoA Escherichia fergusonii ATCC 35469 cytochrome o ubiquinol oxidase subunit II YP_002383691.1 2654088 D 585054 CDS YP_002383692.1 218549901 7122842 2655057..2657048 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90330636, 92345252, 93349845, 9378722, 98021084, 11017202, 2162835, 2168206; Product type c : carrier; cytochrome o ubiquinol oxidase subunit I 2657048 cyoB 7122842 cyoB Escherichia fergusonii ATCC 35469 cytochrome o ubiquinol oxidase subunit I YP_002383692.1 2655057 D 585054 CDS YP_002383693.1 218549902 7124112 2657038..2657652 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90330636, 92345252, 93349845, 9378722, 98021084, 11017202, 2162835, 2168206; Product type c : carrier; cytochrome o ubiquinol oxidase subunit III 2657652 cyoC 7124112 cyoC Escherichia fergusonii ATCC 35469 cytochrome o ubiquinol oxidase subunit III YP_002383693.1 2657038 D 585054 CDS YP_002383694.1 218549903 7122843 2657652..2657981 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90330636, 90366572, 92345252, 9378722, 98021084, 11017202, 2162835; Product type c : carrier; cytochrome o ubiquinol oxidase subunit IV 2657981 cyoD 7122843 cyoD Escherichia fergusonii ATCC 35469 cytochrome o ubiquinol oxidase subunit IV YP_002383694.1 2657652 D 585054 CDS YP_002383695.1 218549904 7122844 2657993..2658883 1 NC_011740.1 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 2658883 cyoE 7122844 cyoE Escherichia fergusonii ATCC 35469 protoheme IX farnesyltransferase YP_002383695.1 2657993 D 585054 CDS YP_002383696.1 218549905 7124113 complement(2659258..2660796) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2660796 7124113 EFER_2590 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383696.1 2659258 R 585054 CDS YP_002383697.1 218549906 7121929 complement(2660855..2661613) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; Regulatory proteins, IclR family 2661613 7121929 EFER_2591 Escherichia fergusonii ATCC 35469 Regulatory proteins, IclR family YP_002383697.1 2660855 R 585054 CDS YP_002383698.1 218549907 7121930 2661723..2662586 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; shikimate dehydrogenase 2662586 7121930 EFER_2592 Escherichia fergusonii ATCC 35469 shikimate dehydrogenase YP_002383698.1 2661723 D 585054 CDS YP_002383699.1 218549908 7121931 2662487..2664259 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; 3-oxosteroid 1-dehydrogenase 2664259 7121931 EFER_2593 Escherichia fergusonii ATCC 35469 3-oxosteroid 1-dehydrogenase YP_002383699.1 2662487 D 585054 CDS YP_002383700.1 218549909 7123949 2664213..2664593 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2664593 7123949 EFER_2594 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383700.1 2664213 D 585054 CDS YP_002383701.1 218549910 7121932 2664604..2666307 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 2666307 7121932 EFER_2595 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383701.1 2664604 D 585054 CDS YP_002383702.1 218549911 7121933 2666375..2667193 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2667193 7121933 EFER_2596 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383702.1 2666375 D 585054 CDS YP_002383703.1 218549912 7123950 2667093..2668568 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; 4-hydroxybenzoate transporter 2668568 7123950 EFER_2597 Escherichia fergusonii ATCC 35469 4-hydroxybenzoate transporter YP_002383703.1 2667093 D 585054 CDS YP_002383704.1 218549913 7121934 2668721..2670085 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; MFS superfamily transporter 2670085 yajR 7121934 yajR Escherichia fergusonii ATCC 35469 MFS superfamily transporter YP_002383704.1 2668721 D 585054 CDS YP_002383705.1 218549914 7123259 complement(2670213..2670704) 1 NC_011740.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein 2670704 yajQ 7123259 yajQ Escherichia fergusonii ATCC 35469 nucleotide-binding protein YP_002383705.1 2670213 R 585054 CDS YP_002383706.1 218549915 7121062 2670872..2671783 1 NC_011740.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 2671783 panE 7121062 panE Escherichia fergusonii ATCC 35469 2-dehydropantoate 2-reductase YP_002383706.1 2670872 D 585054 CDS YP_002383707.1 218549916 7122554 2671746..2672336 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 97039868, 99173753, 99311269; DJ-1 family protein 2672336 yajL 7122554 yajL Escherichia fergusonii ATCC 35469 DJ-1 family protein YP_002383707.1 2671746 D 585054 CDS YP_002383708.1 218549917 7123802 complement(2672390..2673838) 1 NC_011740.1 Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 2673838 thiI 7123802 thiI Escherichia fergusonii ATCC 35469 thiamine biosynthesis protein ThiI YP_002383708.1 2672390 R 585054 CDS YP_002383709.1 218549918 7121994 2674044..2674286 1 NC_011740.1 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 2674286 xseB 7121994 xseB Escherichia fergusonii ATCC 35469 exodeoxyribonuclease VII small subunit YP_002383709.1 2674044 D 585054 CDS YP_002383710.1 218549919 7122386 2674286..2675185 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89291702, 91210228; Product type e : enzyme; geranyltranstransferase 2675185 ispA 7122386 ispA Escherichia fergusonii ATCC 35469 geranyltranstransferase YP_002383710.1 2674286 D 585054 CDS YP_002383711.1 218549920 7120790 2675210..2677072 1 NC_011740.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 2677072 dxs 7120790 dxs Escherichia fergusonii ATCC 35469 1-deoxy-D-xylulose-5-phosphate synthase YP_002383711.1 2675210 D 585054 CDS YP_002383712.1 218549921 7123557 2677252..2678226 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15292217, 16077126; Product type e : enzyme; aldoketo-oxidoreductase 2678226 yajO 7123557 yajO Escherichia fergusonii ATCC 35469 aldoketo-oxidoreductase YP_002383712.1 2677252 D 585054 CDS YP_002383713.1 218549922 7121061 complement(2678280..2678798) 1 NC_011740.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate; phosphatidylglycerophosphatase A 2678798 pgpA 7121061 pgpA Escherichia fergusonii ATCC 35469 phosphatidylglycerophosphatase A YP_002383713.1 2678280 R 585054 CDS YP_002383714.1 218549923 7124068 complement(2678776..2679753) 1 NC_011740.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase 2679753 thiL 7124068 thiL Escherichia fergusonii ATCC 35469 thiamine monophosphate kinase YP_002383714.1 2678776 R 585054 CDS YP_002383715.1 218549924 7121996 complement(2679831..2680250) 1 NC_011740.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 2680250 nusB 7121996 nusB Escherichia fergusonii ATCC 35469 transcription antitermination protein NusB YP_002383715.1 2679831 R 585054 CDS YP_002383716.1 218549925 7119685 complement(2680270..2680740) 1 NC_011740.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 2680740 ribH 7119685 ribH Escherichia fergusonii ATCC 35469 6,7-dimethyl-8-ribityllumazine synthase YP_002383716.1 2680270 R 585054 CDS YP_002383717.1 218549926 7121408 complement(2680828..2681931) 1 NC_011740.1 riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase 2681931 ribD 7121408 ribD Escherichia fergusonii ATCC 35469 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase YP_002383717.1 2680828 R 585054 CDS YP_002383718.1 218549927 7121407 complement(2681935..2682384) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator NrdR 2682384 nrdR 7121407 nrdR Escherichia fergusonii ATCC 35469 transcriptional regulator NrdR YP_002383718.1 2681935 R 585054 CDS YP_002383719.1 218549928 7123028 2682475..2683077 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; hypothetical protein 2683077 yajI 7123028 yajI Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383719.1 2682475 D 585054 CDS YP_002383720.1 218549929 7121060 2683375..2684259 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91092502, 91358319, 93352541; Product type m : membrane component; nucleoside channel phage T6/colicin K receptor 2684259 tsx 7121060 tsx Escherichia fergusonii ATCC 35469 nucleoside channel phage T6/colicin K receptor YP_002383720.1 2683375 D 585054 CDS YP_002383721.1 218549930 7122176 complement(2684297..2684644) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2684644 yajD 7122176 yajD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383721.1 2684297 R 585054 CDS YP_002383722.1 218549931 7123801 complement(2684773..2685744) 1 NC_011740.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 2685744 secF 7123801 secF Escherichia fergusonii ATCC 35469 preprotein translocase subunit SecF YP_002383722.1 2684773 R 585054 CDS YP_002383723.1 218549932 7121763 complement(2685755..2687602) 1 NC_011740.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 2687602 secD 7121763 secD Escherichia fergusonii ATCC 35469 preprotein translocase subunit SecD YP_002383723.1 2685755 R 585054 CDS YP_002383724.1 218549933 7121761 complement(2687630..2687962) 1 NC_011740.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 2687962 yajC 7121761 yajC Escherichia fergusonii ATCC 35469 preprotein translocase subunit YajC YP_002383724.1 2687630 R 585054 CDS YP_002383725.1 218549934 7121058 complement(2687985..2689112) 1 NC_011740.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 2689112 tgt 7121058 tgt Escherichia fergusonii ATCC 35469 queuine tRNA-ribosyltransferase YP_002383725.1 2687985 R 585054 CDS YP_002383726.1 218549935 7121989 complement(2689167..2690237) 1 NC_011740.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 2690237 queA 7121989 queA Escherichia fergusonii ATCC 35469 S-adenosylmethionine--tRNA ribosyltransferase-isomerase YP_002383726.1 2689167 R 585054 CDS YP_002383727.1 218549936 7122341 2690330..2690911 1 NC_011740.1 Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; acyl carrier protein phosphodiesterase 2690911 acpH 7122341 acpH Escherichia fergusonii ATCC 35469 acyl carrier protein phosphodiesterase YP_002383727.1 2690330 D 585054 CDS YP_002383728.1 218549937 7122262 complement(2690916..2692733) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92184757, 1706703, 1918057; Product type e : enzyme; maltodextrin glucosidase 2692733 malZ 7122262 malZ Escherichia fergusonii ATCC 35469 maltodextrin glucosidase YP_002383728.1 2690916 R 585054 CDS YP_002383729.1 218549938 7121229 complement(2692888..2694261) 1 NC_011740.1 cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation; proline-specific permease 2694261 proY 7121229 proY Escherichia fergusonii ATCC 35469 proline-specific permease YP_002383729.1 2692888 R 585054 CDS YP_002383730.1 218549939 7120138 complement(2694338..2695657) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3078876, 6998958, 3550103, 7984428; Product type t : transporter; branched chain amino acid transporter 2695657 brnQ 7120138 brnQ Escherichia fergusonii ATCC 35469 branched chain amino acid transporter YP_002383730.1 2694338 R 585054 CDS YP_002383731.1 218549940 7121677 2695649..2695849 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2695849 7121677 EFER_2625 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383731.1 2695649 D 585054 CDS YP_002383732.1 218549941 7121935 complement(2696062..2697357) 1 NC_011740.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; phosphate regulon sensor protein 2697357 phoR 7121935 phoR Escherichia fergusonii ATCC 35469 phosphate regulon sensor protein YP_002383732.1 2696062 R 585054 CDS YP_002383733.1 218549942 7122603 complement(2697416..2698105) 1 NC_011740.1 two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB; transcriptional regulator PhoB 2698105 phoB 7122603 phoB Escherichia fergusonii ATCC 35469 transcriptional regulator PhoB YP_002383733.1 2697416 R 585054 CDS YP_002383734.1 218549943 7122598 2698251..2699495 1 NC_011740.1 with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity; exonuclease subunit SbcD 2699495 sbcD 7122598 sbcD Escherichia fergusonii ATCC 35469 exonuclease subunit SbcD YP_002383734.1 2698251 D 585054 CDS YP_002383735.1 218549944 7121194 2699492..2702635 1 NC_011740.1 with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity; exonuclease subunit SbcC 2702635 7121194 EFER_2629 Escherichia fergusonii ATCC 35469 exonuclease subunit SbcC YP_002383735.1 2699492 D 585054 CDS YP_002383736.1 218549945 7121936 complement(2702752..2703804) 1 NC_011740.1 catalyzes phosphorylation of fructose; cytosolic enzyme; fructokinase 2703804 mak 7121936 mak Escherichia fergusonii ATCC 35469 fructokinase YP_002383736.1 2702752 R 585054 CDS YP_002383737.1 218549946 7123286 2703791..2704702 1 NC_011740.1 Required for efficient pilin antigenic variation; recombination associated protein 2704702 rdgC 7123286 rdgC Escherichia fergusonii ATCC 35469 recombination associated protein YP_002383737.1 2703791 D 585054 CDS YP_002383738.1 218549947 7122356 complement(2704741..2705025) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2705025 yaiE 7122356 yaiE Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383738.1 2704741 R 585054 CDS YP_002383739.1 218549948 7121053 complement(2705096..2705773) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2705773 7121053 EFER_2633 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383739.1 2705096 R 585054 CDS YP_002383740.1 218549949 7121937 complement(2706020..2706211) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2706211 yaiA 7121937 yaiA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383740.1 2706020 R 585054 CDS YP_002383741.1 218549950 7121051 complement(2706239..2706784) 1 NC_011740.1 type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 2706784 aroL 7121051 aroL Escherichia fergusonii ATCC 35469 shikimate kinase YP_002383741.1 2706239 R 585054 CDS YP_002383742.1 218549951 7120552 complement(2706960..2707424) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2707424 yaiI 7120552 yaiI Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383742.1 2706960 R 585054 CDS YP_002383743.1 218549952 7121054 2707566..2708375 1 NC_011740.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 2708375 proC 7121054 proC Escherichia fergusonii ATCC 35469 pyrroline-5-carboxylate reductase YP_002383743.1 2707566 D 585054 CDS YP_002383744.1 218549953 7123109 complement(2708391..2709590) 1 NC_011740.1 catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis; diguanylate cyclase AdrA 2709590 adrA 7123109 adrA Escherichia fergusonii ATCC 35469 diguanylate cyclase AdrA YP_002383744.1 2708391 R 585054 CDS YP_002383745.1 218549954 7123799 complement(2709611..2709931) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3533724, 2160940; Product type f : factor; hypothetical protein 2709931 psiF 7123799 psiF Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383745.1 2709611 R 585054 CDS YP_002383746.1 218549955 7124018 complement(2710071..2711489) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type e : enzyme; alkaline phosphatase 2711489 phoA 7124018 phoA Escherichia fergusonii ATCC 35469 alkaline phosphatase YP_002383746.1 2710071 R 585054 CDS YP_002383747.1 218549956 7122597 complement(2711588..2711848) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2711848 yaiB 7122597 yaiB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383747.1 2711588 R 585054 CDS YP_002383748.1 218549957 7121052 2712312..2713406 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91129242, 92207163; Product type e : enzyme; D-alanine--D-alanine ligase 2713406 ddlA 7121052 ddlA Escherichia fergusonii ATCC 35469 D-alanine--D-alanine ligase YP_002383748.1 2712312 D 585054 CDS YP_002383749.1 218549958 7124119 complement(2713430..2713642) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2713642 yaiZ 7124119 yaiZ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383749.1 2713430 R 585054 CDS YP_002383750.1 218549959 7121057 2713740..2714201 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 2714201 7121057 EFER_2644 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383750.1 2713740 D 585054 CDS YP_002383751.1 218549960 7121938 complement(2714206..2715297) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; lipoprotein 2715297 yaiW 7121938 yaiW Escherichia fergusonii ATCC 35469 lipoprotein YP_002383751.1 2714206 R 585054 CDS YP_002383752.1 218549961 7123800 complement(2715309..2716529) 1 NC_011740.1 in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; transporter 2716529 sbmA 7123800 sbmA Escherichia fergusonii ATCC 35469 transporter YP_002383752.1 2715309 R 585054 CDS YP_002383753.1 218549962 7121750 2717029..2718195 1 NC_011740.1 this protein has no known enzymatic function; beta-lactam binding protein AmpH 2718195 ampH 7121750 ampH Escherichia fergusonii ATCC 35469 beta-lactam binding protein AmpH YP_002383753.1 2717029 D 585054 CDS YP_002383754.1 218549963 7120515 complement(2718196..2718864) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; DNA-binding transcriptional regulator 2718864 yaiV 7120515 yaiV Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YP_002383754.1 2718196 R 585054 CDS YP_002383755.1 218549964 7121056 complement(2718907..2721915) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; flagellin structural protein 2721915 7121056 EFER_2649 Escherichia fergusonii ATCC 35469 flagellin structural protein YP_002383755.1 2718907 R 585054 CDS YP_002383756.1 218549965 7121197 2722423..2723397 1 NC_011740.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 2723397 hemB 7121197 hemB Escherichia fergusonii ATCC 35469 delta-aminolevulinic acid dehydratase YP_002383756.1 2722423 D 585054 CDS YP_002383757.1 218549966 7120637 complement(2723437..2724288) 1 NC_011740.1 catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers; taurine dioxygenase 2724288 tauD 7120637 tauD Escherichia fergusonii ATCC 35469 taurine dioxygenase YP_002383757.1 2723437 R 585054 CDS YP_002383758.1 218549967 7121981 complement(2724285..2725112) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9401024, 96404792; Product type t : transporter; taurine transporter subunit 2725112 tauC 7121981 tauC Escherichia fergusonii ATCC 35469 taurine transporter subunit YP_002383758.1 2724285 R 585054 CDS YP_002383759.1 218549968 7121980 complement(2725109..2725888) 1 NC_011740.1 Part of the ABC transporter complex tauABC involved in taurine import; taurine transporter ATP-binding subunit 2725888 tauB 7121980 tauB Escherichia fergusonii ATCC 35469 taurine transporter ATP-binding subunit YP_002383759.1 2725109 R 585054 CDS YP_002383760.1 218549969 7121979 complement(2725888..2726850) 1 NC_011740.1 with TauB and TauC is responsible for taurine uptake.; taurine transporter substrate binding subunit 2726850 tauA 7121979 tauA Escherichia fergusonii ATCC 35469 taurine transporter substrate binding subunit YP_002383760.1 2725888 R 585054 CDS YP_002383761.1 218549970 7121978 2727499..2728182 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2728182 yaiS 7121978 yaiS Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383761.1 2727499 D 585054 CDS YP_002383762.1 218549971 7121055 2728442..2731675 1 NC_011740.1 forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon; beta-D-galactosidase 2731675 lacZ 7121055 lacZ Escherichia fergusonii ATCC 35469 beta-D-galactosidase YP_002383762.1 2728442 D 585054 CDS YP_002383763.1 218549972 7123303 complement(2731713..2733599) 1 NC_011740.1 catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; propionyl-CoA synthetase 2733599 prpE 7123303 prpE Escherichia fergusonii ATCC 35469 propionyl-CoA synthetase YP_002383763.1 2731713 R 585054 CDS YP_002383764.1 218549973 7120141 complement(2733639..2735090) 1 NC_011740.1 functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C; 2-methylcitrate dehydratase 2735090 prpD 7120141 prpD Escherichia fergusonii ATCC 35469 2-methylcitrate dehydratase YP_002383764.1 2733639 R 585054 CDS YP_002383765.1 218549974 7120140 complement(2735124..2736293) 1 NC_011740.1 catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; methylcitrate synthase 2736293 prpC 7120140 prpC Escherichia fergusonii ATCC 35469 methylcitrate synthase YP_002383765.1 2735124 R 585054 CDS YP_002383766.1 218549975 7120139 complement(2736338..2737228) 1 NC_011740.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; 2-methylisocitrate lyase 2737228 prpB 7120139 prpB Escherichia fergusonii ATCC 35469 2-methylisocitrate lyase YP_002383766.1 2736338 R 585054 CDS YP_002383767.1 218549976 7123650 2737467..2739053 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9325432, 15805526; Product type r : regulator; DNA-binding transcriptional activator 2739053 prpR 7123650 prpR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional activator YP_002383767.1 2737467 D 585054 CDS YP_002383768.1 218549977 7120142 complement(2739151..2739426) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2739426 yahO 7120142 yahO Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383768.1 2739151 R 585054 CDS YP_002383769.1 218549978 7123798 2739612..2740244 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12879215; Product type t : transporter; neutral amino-acid efflux system 2740244 yahN 7123798 yahN Escherichia fergusonii ATCC 35469 neutral amino-acid efflux system YP_002383769.1 2739612 D 585054 CDS YP_002383770.1 218549979 7121050 2740351..2741769 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 2741769 7121050 EFER_2664 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383770.1 2740351 D 585054 CDS YP_002383771.1 218549980 7123304 2741864..2742535 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; gntR family regulatory protein 2742535 7123304 EFER_2665 Escherichia fergusonii ATCC 35469 gntR family regulatory protein YP_002383771.1 2741864 D 585054 CDS YP_002383772.1 218549981 7121320 complement(2742594..2743619) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; L-threonine 3-dehydrogenase 2743619 7121320 EFER_2666 Escherichia fergusonii ATCC 35469 L-threonine 3-dehydrogenase YP_002383772.1 2742594 R 585054 CDS YP_002383773.1 218549982 7121321 complement(2743591..2744880) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; Hexuronate transporter 2744880 7121321 EFER_2667 Escherichia fergusonii ATCC 35469 Hexuronate transporter YP_002383773.1 2743591 R 585054 CDS YP_002383774.1 218549983 7123305 complement(2745180..2746721) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2746721 7123305 EFER_2668 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383774.1 2745180 R 585054 CDS YP_002383775.1 218549984 7121322 complement(2747082..2747519) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2747519 7121322 EFER_2669 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383775.1 2747082 R 585054 CDS YP_002383776.1 218549985 7121323 complement(2747733..2748839) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15995192; Product type e : enzyme; cyclic di-GMP phosphodiesterase 2748839 yahA 7121323 yahA Escherichia fergusonii ATCC 35469 cyclic di-GMP phosphodiesterase YP_002383776.1 2747733 R 585054 CDS YP_002383777.1 218549986 7121041 2749968..2750447 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; acyltransferase 2750447 yedL 7121041 yedL Escherichia fergusonii ATCC 35469 acyltransferase YP_002383777.1 2749968 D 585054 CDS YP_002383778.1 218549987 7121541 2750728..2751579 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 17575004; Product type pe : enzyme; aldo-keto reductase 2751579 7121541 EFER_2672 Escherichia fergusonii ATCC 35469 aldo-keto reductase YP_002383778.1 2750728 D 585054 CDS YP_002383779.1 218549988 7121324 2751606..2752595 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; aldo-keto reductase 2752595 7121324 EFER_2673 Escherichia fergusonii ATCC 35469 aldo-keto reductase YP_002383779.1 2751606 D 585054 CDS YP_002383780.1 218549989 7121325 complement(2752630..2753523) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; LysR family transcriptional regulator 2753523 7121325 EFER_2674 Escherichia fergusonii ATCC 35469 LysR family transcriptional regulator YP_002383780.1 2752630 R 585054 CDS YP_002383781.1 218549990 7123846 2754232..2754492 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 2754492 7123846 EFER_2675 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383781.1 2754232 D 585054 CDS YP_002383782.1 218549991 7121326 complement(2755065..2755649) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; tail fiber chaperone; Qin prophage 2755649 tfaQ 7121326 tfaQ Escherichia fergusonii ATCC 35469 tail fiber chaperone; Qin prophage YP_002383782.1 2755065 R 585054 CDS YP_002383783.1 218549992 7121987 complement(2755649..2757430) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; tail fiber protein (fragment) 2757430 7121987 EFER_2677 Escherichia fergusonii ATCC 35469 tail fiber protein (fragment) YP_002383783.1 2755649 R 585054 CDS YP_002383784.1 218549993 7121327 complement(2757330..2757893) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; tail protein I 2757893 I 7121327 I Escherichia fergusonii ATCC 35469 tail protein I YP_002383784.1 2757330 R 585054 CDS YP_002383785.1 218549994 7120716 complement(2757883..2758803) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Baseplate assembly protein J (GpJ) 2758803 GpJ 7120716 GpJ Escherichia fergusonii ATCC 35469 Baseplate assembly protein J (GpJ) YP_002383785.1 2757883 R 585054 CDS YP_002383786.1 218549995 7120609 complement(2758787..2759140) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; baseplate assembly protein W 2759140 W 7120609 W Escherichia fergusonii ATCC 35469 baseplate assembly protein W YP_002383786.1 2758787 R 585054 CDS YP_002383787.1 218549996 7124080 complement(2759181..2760332) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; Phage late control gene D protein 2760332 7124080 EFER_2681 Escherichia fergusonii ATCC 35469 Phage late control gene D protein YP_002383787.1 2759181 R 585054 CDS YP_002383788.1 218549997 7121328 complement(2760301..2760516) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; tail protein X 2760516 X 7121328 X Escherichia fergusonii ATCC 35469 tail protein X YP_002383788.1 2760301 R 585054 CDS YP_002383789.1 218549998 7122380 complement(2760491..2760961) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; Phage-related tail protein 2760961 7122380 EFER_2683 Escherichia fergusonii ATCC 35469 Phage-related tail protein YP_002383789.1 2760491 R 585054 CDS YP_002383790.1 218549999 7121329 complement(2760958..2762868) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; hypothetical protein 2762868 7121329 EFER_2684 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383790.1 2760958 R 585054 CDS YP_002383791.1 218550000 7121330 complement(2762971..2763282) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 2763282 7121330 EFER_2685 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383791.1 2762971 R 585054 CDS YP_002383792.1 218550001 7121331 complement(2763329..2763835) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; major tail tube protein 2763835 7121331 EFER_2686 Escherichia fergusonii ATCC 35469 major tail tube protein YP_002383792.1 2763329 R 585054 CDS YP_002383793.1 218550002 7123306 complement(2763832..2765376) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; major tail sheath protein 2765376 7123306 EFER_2687 Escherichia fergusonii ATCC 35469 major tail sheath protein YP_002383793.1 2763832 R 585054 CDS YP_002383794.1 218550003 7121332 complement(2765339..2765995) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7483254; Product type h : extrachromosomal origin; Baseplate assembly protein V (GpV) 2765995 V 7121332 V Escherichia fergusonii ATCC 35469 Baseplate assembly protein V (GpV) YP_002383794.1 2765339 R 585054 CDS YP_002383795.1 218550004 7122654 complement(2765949..2766500) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2766500 7122654 EFER_2689 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383795.1 2765949 R 585054 CDS YP_002383796.1 218550005 7121333 complement(2766511..2767260) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2767260 7121333 EFER_2690 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383796.1 2766511 R 585054 CDS YP_002383797.1 218550006 7121334 complement(2767169..2767579) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2767579 7121334 EFER_2691 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383797.1 2767169 R 585054 CDS YP_002383798.1 218550007 7121335 complement(2767525..2767854) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2767854 7121335 EFER_2692 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383798.1 2767525 R 585054 CDS YP_002383799.1 218550008 7123847 complement(2767926..2770199) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; ATP-dependent Clp protease proteolytic subunit (Endopeptidase Clp) of prophage 2770199 7123847 EFER_2693 Escherichia fergusonii ATCC 35469 ATP-dependent Clp protease proteolytic subunit (Endopeptidase Clp) of prophage YP_002383799.1 2767926 R 585054 CDS YP_002383800.1 218550009 7121336 complement(2769961..2771472) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; head-tail preconnector protein from phage origin 2771472 7121336 EFER_2694 Escherichia fergusonii ATCC 35469 head-tail preconnector protein from phage origin YP_002383800.1 2769961 R 585054 CDS YP_002383801.1 218550010 7121337 complement(2771481..2771696) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2771696 7121337 EFER_2695 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383801.1 2771481 R 585054 CDS YP_002383802.1 218550011 7121338 complement(2771693..2773810) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; DNA packaging protein of prophage ( terminase large subunit) 2773810 7121338 EFER_2696 Escherichia fergusonii ATCC 35469 DNA packaging protein of prophage ( terminase large subunit) YP_002383802.1 2771693 R 585054 CDS YP_002383803.1 218550012 7121339 complement(2773814..2774332) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2774332 7121339 EFER_2697 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383803.1 2773814 R 585054 CDS YP_002383804.1 218550013 7123848 complement(2774460..2774696) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 2774696 7123848 EFER_2698 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383804.1 2774460 R 585054 CDS YP_002383805.1 218550014 7121340 2774865..2775206 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 95173101; Product type pm : membrane component; lipoprotein; DLP12 prophage 2775206 borD 7121340 borD Escherichia fergusonii ATCC 35469 lipoprotein; DLP12 prophage YP_002383805.1 2774865 D 585054 CDS YP_002383806.1 218550015 7123906 complement(2775238..2775711) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2019562; Product type pe : enzyme; murein endopeptidase; DLP12 prophage 2775711 rzpD 7123906 rzpD Escherichia fergusonii ATCC 35469 murein endopeptidase; DLP12 prophage YP_002383806.1 2775238 R 585054 CDS YP_002383807.1 218550016 7121188 complement(2775696..2776193) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3017988; Product type pe : enzyme; lysozyme; DLP12 prophage 2776193 ybcS 7121188 ybcS Escherichia fergusonii ATCC 35469 lysozyme; DLP12 prophage YP_002383807.1 2775696 R 585054 CDS YP_002383808.1 218550017 7121089 complement(2776193..2776408) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2019562; Product type pe : enzyme; phage lysis protein S; DLP12 prophage 2776408 essD 7121089 essD Escherichia fergusonii ATCC 35469 phage lysis protein S; DLP12 prophage YP_002383808.1 2776193 R 585054 CDS YP_002383809.1 218550018 7119964 complement(2776597..2777337) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; araC-type regulatory protein from bacteriophage origin 2777337 7119964 EFER_2703 Escherichia fergusonii ATCC 35469 araC-type regulatory protein from bacteriophage origin YP_002383809.1 2776597 R 585054 CDS YP_002383810.1 218550019 7121341 complement(2777678..2778637) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2778637 7121341 EFER_2704 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383810.1 2777678 R 585054 CDS YP_002383811.1 218550020 7121342 2778830..2779354 1 NC_011740.1 lipocalin; globomycin-sensitive outer membrane lipoprotein; outer membrane lipoprotein Blc 2779354 blc 7121342 blc Escherichia fergusonii ATCC 35469 outer membrane lipoprotein Blc YP_002383811.1 2778830 D 585054 CDS YP_002383812.1 218550021 7121674 complement(2779509..2779901) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8648624, 9278503; Product type pf : factor; antitermination protein Q-like protein; DLP12 prophage 2779901 ybcQ 7121674 ybcQ Escherichia fergusonii ATCC 35469 antitermination protein Q-like protein; DLP12 prophage YP_002383812.1 2779509 R 585054 CDS YP_002383813.1 218550022 7121088 complement(2780109..2780471) 1 NC_011740.1 DLP12 prophage; Holliday junction resolvase; endodeoxyribonuclease RUS 2780471 rusA 7121088 rusA Escherichia fergusonii ATCC 35469 endodeoxyribonuclease RUS YP_002383813.1 2780109 R 585054 CDS YP_002383814.1 218550023 7121166 complement(2780468..2780758) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2780758 ybcO 7121166 ybcO Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383814.1 2780468 R 585054 CDS YP_002383815.1 218550024 7121087 complement(2780751..2781002) 1 NC_011740.1 DLP12 prophage; conserved protein similar to phage 82 and lambda proteins; prophage protein NinE 2781002 7121087 EFER_2709 Escherichia fergusonii ATCC 35469 prophage protein NinE YP_002383815.1 2780751 R 585054 CDS YP_002383816.1 218550025 7121343 complement(2780921..2781376) 1 NC_011740.1 DLP12 prophage; hypothetical protein 2781376 ybcN 7121343 ybcN Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383816.1 2780921 R 585054 CDS YP_002383817.1 218550026 7121086 complement(2781564..2782073) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 2782073 7121086 EFER_2711 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383817.1 2781564 R 585054 CDS YP_002383818.1 218550027 7121344 complement(2782123..2782344) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 2782344 7121344 EFER_2712 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383818.1 2782123 R 585054 CDS YP_002383819.1 218550028 7121345 complement(2782465..2783175) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2783175 7121345 EFER_2713 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383819.1 2782465 R 585054 CDS YP_002383820.1 218550029 7123849 complement(2783172..2783585) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2783585 7123849 EFER_2714 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383820.1 2783172 R 585054 CDS YP_002383821.1 218550030 7121346 complement(2783582..2783812) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2783812 7121346 EFER_2715 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383821.1 2783582 R 585054 CDS YP_002383822.1 218550031 7121347 complement(2783809..2784066) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 2784066 7121347 EFER_2716 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383822.1 2783809 R 585054 CDS YP_002383823.1 218550032 7123850 complement(2784006..2784299) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Ren protein from phage origin 2784299 7123850 EFER_2717 Escherichia fergusonii ATCC 35469 Ren protein from phage origin YP_002383823.1 2784006 R 585054 CDS YP_002383824.1 218550033 7121348 complement(2784296..2784997) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; replication protein P of bacteriophage 2784997 7121348 EFER_2718 Escherichia fergusonii ATCC 35469 replication protein P of bacteriophage YP_002383824.1 2784296 R 585054 CDS YP_002383825.1 218550034 7123851 complement(2784994..2786013) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2995831; Product type h : extrachromosomal origin; Replication protein O frm phage origin 2786013 7123851 EFER_2719 Escherichia fergusonii ATCC 35469 Replication protein O frm phage origin YP_002383825.1 2784994 R 585054 CDS YP_002383826.1 218550035 7121349 complement(2786010..2786501) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 612476; Product type h : extrachromosomal origin; Regulatory protein CII from bacteriophage origin; coiled-coil 2786501 7121349 EFER_2720 Escherichia fergusonii ATCC 35469 Regulatory protein CII from bacteriophage origin; coiled-coil YP_002383826.1 2786010 R 585054 CDS YP_002383827.1 218550036 7121350 complement(2786580..2786813) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; represror Cro 2786813 cro 7121350 cro Escherichia fergusonii ATCC 35469 represror Cro YP_002383827.1 2786580 R 585054 CDS YP_002383828.1 218550037 7122807 2786882..2787610 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Regulatory protein CI from bacteriophage origin 2787610 7122807 EFER_2722 Escherichia fergusonii ATCC 35469 Regulatory protein CI from bacteriophage origin YP_002383828.1 2786882 D 585054 CDS YP_002383829.1 218550038 7121351 2787740..2788879 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; peptidase m, neutral zinc metallopeptidases, zinc-binding site; protein 2788879 7121351 EFER_2723 Escherichia fergusonii ATCC 35469 peptidase m, neutral zinc metallopeptidases, zinc-binding site; protein YP_002383829.1 2787740 D 585054 CDS YP_002383830.1 218550039 7121352 2788876..2789388 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2789388 7121352 EFER_2724 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383830.1 2788876 D 585054 CDS YP_002383831.1 218550040 7123307 2789663..2790073 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; prophage Kil protein 2790073 7123307 EFER_2725 Escherichia fergusonii ATCC 35469 prophage Kil protein YP_002383831.1 2789663 D 585054 CDS YP_002383832.1 218550041 7121353 2790149..2790445 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; host-nuclease inhibitor protein Gam of bacteriophage 2790445 7121353 EFER_2726 Escherichia fergusonii ATCC 35469 host-nuclease inhibitor protein Gam of bacteriophage YP_002383832.1 2790149 D 585054 CDS YP_002383833.1 218550042 7123852 2790451..2791236 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 6458018, 6221115; Product type h : extrachromosomal origin; Recombination protein bet from phage origin 2791236 7123852 EFER_2727 Escherichia fergusonii ATCC 35469 Recombination protein bet from phage origin YP_002383833.1 2790451 D 585054 CDS YP_002383834.1 218550043 7121354 2791233..2791913 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; exonuclease from phage origin 2791913 7121354 EFER_2728 Escherichia fergusonii ATCC 35469 exonuclease from phage origin YP_002383834.1 2791233 D 585054 CDS YP_002383835.1 218550044 7121355 2792064..2792621 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; DNA N-6-adenine-methyltransferase from phage origin 2792621 7121355 EFER_2729 Escherichia fergusonii ATCC 35469 DNA N-6-adenine-methyltransferase from phage origin YP_002383835.1 2792064 D 585054 CDS YP_002383836.1 218550045 7123853 2792599..2792913 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2792913 7123853 EFER_2730 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383836.1 2792599 D 585054 CDS YP_002383837.1 218550046 7121356 2793012..2793230 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2793230 7121356 EFER_2731 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383837.1 2793012 D 585054 CDS YP_002383838.1 218550047 7123854 2793278..2793556 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2793556 7123854 EFER_2732 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383838.1 2793278 D 585054 CDS YP_002383839.1 218550048 7121357 2793553..2793972 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 11401961, 12379716; Product type h : extrachromosomal origin; Excisionase from phage origin 2793972 xis 7121357 xis Escherichia fergusonii ATCC 35469 Excisionase from phage origin YP_002383839.1 2793553 D 585054 CDS YP_002383840.1 218550049 7123472 2793849..2795009 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 3491212, 12562822; Product type h : extrachromosomal origin; Integrase from phage origin 2795009 int 7123472 int Escherichia fergusonii ATCC 35469 Integrase from phage origin YP_002383840.1 2793849 D 585054 CDS YP_002383841.1 218550050 7120070 complement(2795214..2796467) 1 NC_011740.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 2796467 proA 7120070 proA Escherichia fergusonii ATCC 35469 gamma-glutamyl phosphate reductase YP_002383841.1 2795214 R 585054 CDS YP_002383842.1 218550051 7120132 complement(2796479..2797582) 1 NC_011740.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 2797582 proB 7120132 proB Escherichia fergusonii ATCC 35469 gamma-glutamyl kinase YP_002383842.1 2796479 R 585054 CDS YP_002383843.1 218550052 7120133 2797870..2798925 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89178658, 89380253, 92219258, 98090453, 1380671, 1848301, 1848682, 6089111, 6341601, 7679770; Product type t : transporter; outer membrane phosphoporin protein E 2798925 phoE 7120133 phoE Escherichia fergusonii ATCC 35469 outer membrane phosphoporin protein E YP_002383843.1 2797870 D 585054 CDS YP_002383844.1 218550053 7122599 complement(2798964..2799365) 1 NC_011740.1 involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS; DNA-binding transcriptional regulator Crl 2799365 crl 7122599 crl Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator Crl YP_002383844.1 2798964 R 585054 CDS YP_002383845.1 218550054 7122806 complement(2799423..2800667) 1 NC_011740.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; fermentation/respiration switch protein 2800667 frsA 7122806 frsA Escherichia fergusonii ATCC 35469 fermentation/respiration switch protein YP_002383845.1 2799423 R 585054 CDS YP_002383846.1 218550055 7123014 complement(2800760..2801218) 1 NC_011740.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 2801218 gpt 7123014 gpt Escherichia fergusonii ATCC 35469 xanthine-guanine phosphoribosyltransferase YP_002383846.1 2800760 R 585054 CDS YP_002383847.1 218550056 7120613 2801479..2802936 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1695895, 21101837, 88121730, 92204123, 2651887; Product type e : enzyme; aminoacyl-histidine dipeptidase ABC transporter periplasmic-binding protein 2802936 pepD 7120613 pepD Escherichia fergusonii ATCC 35469 aminoacyl-histidine dipeptidase ABC transporter periplasmic-binding protein YP_002383847.1 2801479 D 585054 CDS YP_002383848.1 218550057 7122576 2802963..2803226 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2803226 7122576 EFER_2742 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383848.1 2802963 D 585054 CDS YP_002383849.1 218550058 7121358 complement(2803235..2803813) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2803813 7121358 EFER_2743 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383849.1 2803235 R 585054 CDS YP_002383850.1 218550059 7121359 complement(2803821..2804321) 1 NC_011740.1 similar to release factor 1 and 2; peptide chain release factor-like protein 2804321 prfH 7121359 prfH Escherichia fergusonii ATCC 35469 peptide chain release factor-like protein YP_002383850.1 2803821 R 585054 CDS YP_002383851.1 218550060 7123647 complement(2804432..2805571) 1 NC_011740.1 mutations in this gene result in a compromised ability for drug-inducible mexXY expression; expression is inducible by the same ribosome-targeting agents that induce mexXY; hypothetical protein 2805571 7123647 EFER_2745 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383851.1 2804432 R 585054 CDS YP_002383852.1 218550061 7121360 complement(2805889..2806341) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12813093; Product type pe : enzyme; hypothetical protein 2806341 yafP 7121360 yafP Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383852.1 2805889 R 585054 CDS YP_002383853.1 218550062 7124035 complement(2806351..2806749) 1 NC_011740.1 YafO overproduction induces toxicity; it is believed to be the toxin of a toxin-antitoxin pair; unknown function; toxin YafO 2806749 yafO 7124035 yafO Escherichia fergusonii ATCC 35469 toxin YafO YP_002383853.1 2806351 R 585054 CDS YP_002383854.1 218550063 7122422 complement(2806752..2807045) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12813093, 14594833; Product type pf : factor; antitoxin of the YafO-YafN toxin-antitoxin system 2807045 yafN 7122422 yafN Escherichia fergusonii ATCC 35469 antitoxin of the YafO-YafN toxin-antitoxin system YP_002383854.1 2806752 R 585054 CDS YP_002383855.1 218550064 7122421 complement(2807097..2808152) 1 NC_011740.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 2808152 dinB 7122421 dinB Escherichia fergusonii ATCC 35469 DNA polymerase IV YP_002383855.1 2807097 R 585054 CDS YP_002383856.1 218550065 7122897 complement(2808223..2809113) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type s : structure; hypothetical protein 2809113 mbhA 7122897 mbhA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383856.1 2808223 R 585054 CDS YP_002383857.1 218550066 7121236 2808563..2810692 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 7783646, 15687208; Product type s : structure; flagellar system protein 2810692 fhiA 7121236 fhiA Escherichia fergusonii ATCC 35469 flagellar system protein YP_002383857.1 2808563 D 585054 CDS YP_002383858.1 218550067 7123089 complement(2810777..2812597) 1 NC_011740.1 helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit alpha 2812597 recD 7123089 recD Escherichia fergusonii ATCC 35469 exonuclease V subunit alpha YP_002383858.1 2810777 R 585054 CDS YP_002383859.1 218550068 7122361 complement(2812594..2816154) 1 NC_011740.1 helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit beta 2816154 recB 7122361 recB Escherichia fergusonii ATCC 35469 exonuclease V subunit beta YP_002383859.1 2812594 R 585054 CDS YP_002383860.1 218550069 7122359 complement(2816138..2819026) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91193232, 1570301, 3308636, 3534791, 3537960, 8099278; Product type e : enzyme; protease III 2819026 ptr 7122359 ptr Escherichia fergusonii ATCC 35469 protease III YP_002383860.1 2816138 R 585054 CDS YP_002383861.1 218550070 7123461 complement(2819203..2822571) 1 NC_011740.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination; exonuclease V subunit gamma 2822571 recC 7123461 recC Escherichia fergusonii ATCC 35469 exonuclease V subunit gamma YP_002383861.1 2819203 R 585054 CDS YP_002383862.1 218550071 7122360 complement(2822587..2822907) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2822907 7122360 EFER_2756 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383862.1 2822587 R 585054 CDS YP_002383863.1 218550072 7123308 complement(2822892..2823296) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2823296 7123308 EFER_2757 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383863.1 2822892 R 585054 CDS YP_002383864.1 218550073 7121361 complement(2823293..2824096) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type f : factor; prepilin peptidase-dependent protein B 2824096 ppdB 7121361 ppdB Escherichia fergusonii ATCC 35469 prepilin peptidase-dependent protein B YP_002383864.1 2823293 R 585054 CDS YP_002383865.1 218550074 7123645 complement(2823847..2824317) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; hypothetical protein 2824317 ppdA 7123645 ppdA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383865.1 2823847 R 585054 CDS YP_002383866.1 218550075 7120108 complement(2824492..2825286) 1 NC_011740.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 2825286 thyA 7120108 thyA Escherichia fergusonii ATCC 35469 thymidylate synthase YP_002383866.1 2824492 R 585054 CDS YP_002383867.1 218550076 7123984 complement(2825293..2826168) 1 NC_011740.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 2826168 lgt 7123984 lgt Escherichia fergusonii ATCC 35469 prolipoprotein diacylglyceryl transferase YP_002383867.1 2825293 R 585054 CDS YP_002383868.1 218550077 7120830 complement(2826332..2828578) 1 NC_011740.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; bifunctional phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain-containing protein 2828578 ptsP 7120830 ptsP Escherichia fergusonii ATCC 35469 bifunctional phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain-containing protein YP_002383868.1 2826332 R 585054 CDS YP_002383869.1 218550078 7122317 complement(2828591..2829121) 1 NC_011740.1 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 2829121 nudH 7122317 nudH Escherichia fergusonii ATCC 35469 dinucleoside polyphosphate hydrolase YP_002383869.1 2828591 R 585054 CDS YP_002383870.1 218550079 7119673 2829795..2830499 1 NC_011740.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 2830499 mutH 7119673 mutH Escherichia fergusonii ATCC 35469 DNA mismatch repair protein YP_002383870.1 2829795 D 585054 CDS YP_002383871.1 218550080 7120652 2830563..2831276 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2831276 ygdQ 7120652 ygdQ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383871.1 2830563 D 585054 CDS YP_002383872.1 218550081 7123878 2831409..2831627 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2831627 ygdR 7123878 ygdR Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383872.1 2831409 D 585054 CDS YP_002383873.1 218550082 7121504 2831735..2832775 1 NC_011740.1 complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; aldo-keto reductase 2832775 tas 7121504 tas Escherichia fergusonii ATCC 35469 aldo-keto reductase YP_002383873.1 2831735 D 585054 CDS YP_002383874.1 218550083 7123406 2832918..2834588 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2834588 7123406 EFER_2768 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383874.1 2832918 D 585054 CDS YP_002383875.1 218550084 7121362 complement(2834627..2835820) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8300626; Product type pm : membrane component; lysophospholipid transporter LplT 2835820 ygeD 7121362 ygeD Escherichia fergusonii ATCC 35469 lysophospholipid transporter LplT YP_002383875.1 2834627 R 585054 CDS YP_002383876.1 218550085 7121505 complement(2835813..2837972) 1 NC_011740.1 Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase 2837972 aas 7121505 aas Escherichia fergusonii ATCC 35469 bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase YP_002383876.1 2835813 R 585054 CDS YP_002383877.1 218550086 7119696 complement(2838255..2838554) 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 2838554 7119696 EFER_2771 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383877.1 2838255 R 585054 CDS YP_002383878.1 218550087 7119697 2838567..2839595 1 NC_011740.1 controls transcription of galETKM; DNA-binding transcriptional regulator GalR 2839595 galR 7119697 galR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator GalR YP_002383878.1 2838567 D 585054 CDS YP_002383879.1 218550088 7120169 complement(2839610..2840872) 1 NC_011740.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding; diaminopimelate decarboxylase 2840872 lysA 7120169 lysA Escherichia fergusonii ATCC 35469 diaminopimelate decarboxylase YP_002383879.1 2839610 R 585054 CDS YP_002383880.1 218550089 7121214 2840982..2841917 1 NC_011740.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase; DNA-binding transcriptional regulator LysR 2841917 lysR 7121214 lysR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator LysR YP_002383880.1 2840982 D 585054 CDS YP_002383881.1 218550090 7121217 complement(2841922..2843103) 1 NC_011740.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase 2843103 yqeF 7121217 yqeF Escherichia fergusonii ATCC 35469 acetyl-CoA acetyltransferase YP_002383881.1 2841922 R 585054 CDS YP_002383882.1 218550091 7119722 2843347..2844576 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter 2844576 yqeG 7119722 yqeG Escherichia fergusonii ATCC 35469 transporter YP_002383882.1 2843347 D 585054 CDS YP_002383883.1 218550092 7119723 2845019..2845747 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; hypothetical protein 2845747 yqeH 7119723 yqeH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383883.1 2845019 D 585054 CDS YP_002383884.1 218550093 7123583 2845989..2846912 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; regulatory protein 2846912 7123583 EFER_2778 Escherichia fergusonii ATCC 35469 regulatory protein YP_002383884.1 2845989 D 585054 CDS YP_002383885.1 218550094 7121364 2846905..2847387 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2847387 7121364 EFER_2779 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383885.1 2846905 D 585054 CDS YP_002383886.1 218550095 7123309 2847666..2849918 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89359086, 94042873, 94042874; Product type m : membrane component; bacteriophage N4 adsorption protein B 2849918 nfrB 7123309 nfrB Escherichia fergusonii ATCC 35469 bacteriophage N4 adsorption protein B YP_002383886.1 2847666 D 585054 CDS YP_002383887.1 218550096 7120688 2849887..2852877 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8226649; bacteriophage N4 receptor, outer membrane subunit 2852877 nfrA 7120688 nfrA Escherichia fergusonii ATCC 35469 bacteriophage N4 receptor, outer membrane subunit YP_002383887.1 2849887 D 585054 CDS YP_002383888.1 218550097 7120687 2852877..2853770 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2853770 ybcH 7120687 ybcH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383888.1 2852877 D 585054 CDS YP_002383889.1 218550098 7121083 2854043..2855302 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92349961; Product type t : transporter; cytosine permease 2855302 codB 7121083 codB Escherichia fergusonii ATCC 35469 cytosine permease YP_002383889.1 2854043 D 585054 CDS YP_002383890.1 218550099 7123994 2855292..2856575 1 NC_011740.1 Catalyzes the deamination of cytosine to uracil and ammonia; cytosine deaminase 2856575 codA 7123994 codA Escherichia fergusonii ATCC 35469 cytosine deaminase YP_002383890.1 2855292 D 585054 CDS YP_002383891.1 218550100 7120912 complement(2856796..2858532) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2858532 7120912 EFER_2786 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383891.1 2856796 R 585054 CDS YP_002383892.1 218550101 7121365 2858775..2859131 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2859131 7121365 EFER_2787 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383892.1 2858775 D 585054 CDS YP_002383893.1 218550102 7121366 complement(2858916..2859818) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2859818 7121366 EFER_2788 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383893.1 2858916 R 585054 CDS YP_002383894.1 218550103 7121367 complement(2859933..2860121) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; protein perC (protein bfpW) (fragment) 2860121 7121367 EFER_2789 Escherichia fergusonii ATCC 35469 protein perC (protein bfpW) (fragment) YP_002383894.1 2859933 R 585054 CDS YP_002383895.1 218550104 7121368 complement(2860236..2860460) 1 NC_011740.1 hypothetical protein 2860460 7121368 EFER_2790 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383895.1 2860236 R 585054 CDS YP_002383896.1 218550105 7123855 2860535..2860843 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type h : extrachromosomal origin; IS3 element protein InsE 2860843 insE 7123855 insE Escherichia fergusonii ATCC 35469 IS3 element protein InsE YP_002383896.1 2860535 D 585054 CDS YP_002383897.1 218550106 7123745 2860840..2861706 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type h : extrachromosomal origin; IS3 element protein InsF 2861706 insF 7123745 insF Escherichia fergusonii ATCC 35469 IS3 element protein InsF YP_002383897.1 2860840 D 585054 CDS YP_002383898.1 218550107 7120743 2861798..2862229 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2862229 7120743 EFER_2793 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383898.1 2861798 D 585054 CDS YP_002383899.1 218550108 7121369 2862316..2862525 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; regulatory protein 2862525 7121369 EFER_2794 Escherichia fergusonii ATCC 35469 regulatory protein YP_002383899.1 2862316 D 585054 CDS YP_002383900.1 218550109 7121370 2862607..2863674 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2863674 7121370 EFER_2795 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383900.1 2862607 D 585054 CDS YP_002383901.1 218550110 7121371 2863953..2864858 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2864858 7121371 EFER_2796 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383901.1 2863953 D 585054 CDS YP_002383902.1 218550111 7121372 2864855..2865043 1 NC_011740.1 hypothetical protein 2865043 7121372 EFER_2797 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383902.1 2864855 D 585054 CDS YP_002383903.1 218550112 7123856 complement(2865229..2865771) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2865771 7123856 EFER_2798 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383903.1 2865229 R 585054 CDS YP_002383904.1 218550113 7121373 complement(2865689..2866528) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type pe : enzyme; transposase ORF B, IS911 2866528 7121373 EFER_2799 Escherichia fergusonii ATCC 35469 transposase ORF B, IS911 YP_002383904.1 2865689 R 585054 CDS YP_002383905.1 218550114 7121375 2866973..2867443 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; marR-family regulatory protein 2867443 7121375 EFER_2801 Escherichia fergusonii ATCC 35469 marR-family regulatory protein YP_002383905.1 2866973 D 585054 CDS YP_002383906.1 218550115 7120554 complement(2867785..2868138) 1 NC_011740.1 regulates the expression of of the arsRBC involved in resistance to arsenic; DNA-binding transcriptional repressor ArsR 2868138 7120554 EFER_2803 Escherichia fergusonii ATCC 35469 DNA-binding transcriptional repressor ArsR YP_002383906.1 2867785 R 585054 CDS YP_002383907.1 218550116 7123857 2868232..2870280 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2870280 7123857 EFER_2804 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383907.1 2868232 D 585054 CDS YP_002383908.1 218550117 7121377 2870259..2872043 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; helicase 2872043 7121377 EFER_2805 Escherichia fergusonii ATCC 35469 helicase YP_002383908.1 2870259 D 585054 CDS YP_002383909.1 218550118 7123858 complement(2872100..2873269) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Integrase 2873269 int 7123858 int Escherichia fergusonii ATCC 35469 Integrase YP_002383909.1 2872100 R 585054 CDS YP_002383910.1 218550119 7120069 complement(2873586..2874344) 1 NC_011740.1 Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 15150243; Product type r : regulator; Tetratricopeptide repeat transcriptional regulator 2874344 ygeR 7120069 ygeR Escherichia fergusonii ATCC 35469 Tetratricopeptide repeat transcriptional regulator YP_002383910.1 2873586 R 585054 CDS YP_002383911.1 218550120 7123330 complement(2874428..2875159) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 2875159 7123330 EFER_2808 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383911.1 2874428 R 585054 CDS YP_002383912.1 218550121 7121378 complement(2875164..2875994) 1 NC_011740.1 extracellular solute-binding protein 2875994 7121378 EFER_2809 Escherichia fergusonii ATCC 35469 extracellular solute-binding protein YP_002383912.1 2875164 R 585054 CDS YP_002383913.1 218550122 7121379 complement(2876018..2876890) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; dioxygenase 2876890 7121379 EFER_2810 Escherichia fergusonii ATCC 35469 dioxygenase YP_002383913.1 2876018 R 585054 CDS YP_002383914.1 218550123 7121380 complement(2876914..2878434) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; amino acid ABC transporter permease 2878434 7121380 EFER_2811 Escherichia fergusonii ATCC 35469 amino acid ABC transporter permease YP_002383914.1 2876914 R 585054 CDS YP_002383915.1 218550124 7121157 2878811..2879731 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; regulatory protein, LysR:LysR substrate-binding domain (fragment) 2879731 7121157 EFER_2812 Escherichia fergusonii ATCC 35469 regulatory protein, LysR:LysR substrate-binding domain (fragment) YP_002383915.1 2878811 D 585054 CDS YP_002383916.1 218550125 7123694 2879786..2881114 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; pyridine nucleotide-disulfide oxidoreductase 2881114 7123694 EFER_2813 Escherichia fergusonii ATCC 35469 pyridine nucleotide-disulfide oxidoreductase YP_002383916.1 2879786 D 585054 CDS YP_002383917.1 218550126 7123150 2881129..2881563 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; endoribonuclease 2881563 7123150 EFER_2814 Escherichia fergusonii ATCC 35469 endoribonuclease YP_002383917.1 2881129 D 585054 CDS YP_002383918.1 218550127 7123151 2881560..2882234 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2882234 7123151 EFER_2815 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383918.1 2881560 D 585054 CDS YP_002383919.1 218550128 7120390 2882065..2883402 1 NC_011740.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine; acetylornithine deacetylase 2883402 7120390 EFER_2816 Escherichia fergusonii ATCC 35469 acetylornithine deacetylase YP_002383919.1 2882065 D 585054 CDS YP_002383920.1 218550129 7120391 2883597..2884997 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92155241, 92394884, 99406302, 1522060, 1740158, 7764225, 9298646; Product type e : enzyme; glutamate decarboxylase 2884997 gadA 7120391 gadA Escherichia fergusonii ATCC 35469 glutamate decarboxylase YP_002383920.1 2883597 D 585054 CDS YP_002383921.1 218550130 7120161 2885195..2886142 1 NC_011740.1 catalyzes the formation of glutamate from glutamine; glutaminase 2886142 ybaS 7120161 ybaS Escherichia fergusonii ATCC 35469 glutaminase YP_002383921.1 2885195 D 585054 CDS YP_002383922.1 218550131 7121070 2886267..2886881 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type pe : enzyme; xanthine dehydrogenase, iron-sulfur binding subunit 2886881 yagT 7121070 yagT Escherichia fergusonii ATCC 35469 xanthine dehydrogenase, iron-sulfur binding subunit YP_002383922.1 2886267 D 585054 CDS YP_002383923.1 218550132 7121040 2886878..2887834 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type pe : enzyme; xanthine dehydrogenase yagS, FAD binding subunit 2887834 yagS 7121040 yagS Escherichia fergusonii ATCC 35469 xanthine dehydrogenase yagS, FAD binding subunit YP_002383923.1 2886878 D 585054 CDS YP_002383924.1 218550133 7121039 2887831..2890029 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type pe : enzyme; xanthine dehydrogenase, molybdenum binding subunit 2890029 yagR 7121039 yagR Escherichia fergusonii ATCC 35469 xanthine dehydrogenase, molybdenum binding subunit YP_002383924.1 2887831 D 585054 CDS YP_002383925.1 218550134 7122180 2890039..2890974 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2890974 yagQ 7122180 yagQ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383925.1 2890039 D 585054 CDS YP_002383926.1 218550135 7122425 2890971..2891534 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; MobA-like protein 2891534 7122425 EFER_2823 Escherichia fergusonii ATCC 35469 MobA-like protein YP_002383926.1 2890971 D 585054 CDS YP_002383927.1 218550136 7120392 2891589..2892170 1 NC_011740.1 catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase 2892170 idi 7120392 idi Escherichia fergusonii ATCC 35469 isopentenyl-diphosphate delta-isomerase YP_002383927.1 2891589 D 585054 CDS YP_002383928.1 218550137 7120723 complement(2892213..2893730) 1 NC_011740.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 2893730 lysS 7120723 lysS Escherichia fergusonii ATCC 35469 lysyl-tRNA synthetase YP_002383928.1 2892213 R 585054 CDS YP_002383929.1 218550138 7123285 complement(join(2893740..2894762,2894764..2894838)) 1 NC_011740.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 2894838 prfB 7123285 prfB Escherichia fergusonii ATCC 35469 peptide chain release factor 2 YP_002383929.1 2893740 R 585054 CDS YP_002383930.1 218550139 7120124 complement(2894929..2896662) 1 NC_011740.1 5'-3' single-stranded-DNA-specific exonuclease; ssDNA exonuclease RecJ 2896662 recJ 7120124 recJ Escherichia fergusonii ATCC 35469 ssDNA exonuclease RecJ YP_002383930.1 2894929 R 585054 CDS YP_002383931.1 218550140 7121381 complement(2896668..2897378) 1 NC_011740.1 DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity; thiol:disulfide interchange protein DsbC 2897378 dsbC 7121381 dsbC Escherichia fergusonii ATCC 35469 thiol:disulfide interchange protein DsbC YP_002383931.1 2896668 R 585054 CDS YP_002383932.1 218550141 7122922 complement(2897403..2898299) 1 NC_011740.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 2898299 xerD 7122922 xerD Escherichia fergusonii ATCC 35469 site-specific tyrosine recombinase XerD YP_002383932.1 2897403 R 585054 CDS YP_002383933.1 218550142 7124029 2898411..2898932 1 NC_011740.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic; flavodoxin FldB 2898932 fldB 7124029 fldB Escherichia fergusonii ATCC 35469 flavodoxin FldB YP_002383933.1 2898411 D 585054 CDS YP_002383934.1 218550143 7123562 complement(2898972..2899379) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2899379 ygfX 7123562 ygfX Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383934.1 2898972 R 585054 CDS YP_002383935.1 218550144 7119840 complement(2899360..2899626) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2899626 ygfY 7119840 ygfY Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383935.1 2899360 R 585054 CDS YP_002383936.1 218550145 7119841 complement(2899616..2899774) 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 2899774 7119841 EFER_2833 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383936.1 2899616 R 585054 CDS YP_002383937.1 218550146 7120393 2899878..2900858 1 NC_011740.1 physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator; global regulator 2900858 ygfZ 7120393 ygfZ Escherichia fergusonii ATCC 35469 global regulator YP_002383937.1 2899878 D 585054 CDS YP_002383938.1 218550147 7123059 complement(2900935..2901594) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hemolysin, inner membrane subunit 2901594 yqfA 7123059 yqfA Escherichia fergusonii ATCC 35469 hemolysin, inner membrane subunit YP_002383938.1 2900935 R 585054 CDS YP_002383939.1 218550148 7119724 complement(2901758..2902069) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2902069 yqfB 7119724 yqfB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383939.1 2901758 R 585054 CDS YP_002383940.1 218550149 7123036 2902108..2903547 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87222180, 88297127, 92334140; Product type e : enzyme; 6-phospho-beta-glucosidase 2903547 bglA 7123036 bglA Escherichia fergusonii ATCC 35469 6-phospho-beta-glucosidase YP_002383940.1 2902108 D 585054 CDS YP_002383941.1 218550150 7121660 complement(2903595..2904533) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; outer membrane protein 2904533 7121660 EFER_2838 Escherichia fergusonii ATCC 35469 outer membrane protein YP_002383941.1 2903595 R 585054 CDS YP_002383942.1 218550151 7123152 complement(2904944..2907817) 1 NC_011740.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase 2907817 gcvP 7123152 gcvP Escherichia fergusonii ATCC 35469 glycine dehydrogenase YP_002383942.1 2904944 R 585054 CDS YP_002383943.1 218550152 7120180 complement(2907936..2908325) 1 NC_011740.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 2908325 gcvH 7120180 gcvH Escherichia fergusonii ATCC 35469 glycine cleavage system protein H YP_002383943.1 2907936 R 585054 CDS YP_002383944.1 218550153 7123117 complement(2908348..2909442) 1 NC_011740.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 2909442 gcvT 7123117 gcvT Escherichia fergusonii ATCC 35469 glycine cleavage system aminomethyltransferase T YP_002383944.1 2908348 R 585054 CDS YP_002383945.1 218550154 7120182 complement(2909890..2911092) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1339425; Product type pe : enzyme; hypothetical protein 2911092 visC 7120182 visC Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383945.1 2909890 R 585054 CDS YP_002383946.1 218550155 7122658 complement(2911115..2912293) 1 NC_011740.1 Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase 2912293 ubiH 7122658 ubiH Escherichia fergusonii ATCC 35469 2-octaprenyl-6-methoxyphenyl hydroxylase YP_002383946.1 2911115 R 585054 CDS YP_002383947.1 218550156 7124073 complement(2912290..2913615) 1 NC_011740.1 exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide; proline aminopeptidase P II 2913615 pepP 7124073 pepP Escherichia fergusonii ATCC 35469 proline aminopeptidase P II YP_002383947.1 2912290 R 585054 CDS YP_002383948.1 218550157 7122577 complement(2913641..2914219) 1 NC_011740.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein 2914219 ygfB 7122577 ygfB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383948.1 2913641 R 585054 CDS YP_002383949.1 218550158 7119839 2914387..2914716 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 412171; Product type cp : cell process; Z-ring-associated protein 2914716 zapA 7119839 zapA Escherichia fergusonii ATCC 35469 Z-ring-associated protein YP_002383949.1 2914387 D 585054 CDS YP_002383950.1 218550159 7119771 complement(2914666..2915043) 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 2915043 7119771 EFER_2848 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383950.1 2914666 R 585054 CDS YP_002383951.1 218550160 7121945 2915010..2915558 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14727089, 2579060; Product type pe : enzyme; ligase 2915558 ygfA 7121945 ygfA Escherichia fergusonii ATCC 35469 ligase YP_002383951.1 2915010 D 585054 CDS YP_002383952.1 218550161 7123822 complement(2915945..2917177) 1 NC_011740.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 2917177 serA 7123822 serA Escherichia fergusonii ATCC 35469 D-3-phosphoglycerate dehydrogenase YP_002383952.1 2915945 R 585054 CDS YP_002383953.1 218550162 7121769 complement(2917420..2918079) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12517338, 4598000, 93374859, 1917830, 8366047, 9298646, 9600841, 1104357; Product type e : enzyme; ribose 5-phosphate isomerase 2918079 rpiA 7121769 rpiA Escherichia fergusonii ATCC 35469 ribose 5-phosphate isomerase YP_002383953.1 2917420 R 585054 CDS YP_002383954.1 218550163 7123319 2918239..2919132 1 NC_011740.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 2919132 argP 7123319 argP Escherichia fergusonii ATCC 35469 chromosome replication initiation inhibitor protein YP_002383954.1 2918239 D 585054 CDS YP_002383955.1 218550164 7120542 complement(2919167..2919907) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2919907 yggE 7120542 yggE Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383955.1 2919167 R 585054 CDS YP_002383956.1 218550165 7119843 complement(2920188..2920823) 1 NC_011740.1 Involved in the export of arginine; arginine exporter protein 2920823 argO 7119843 argO Escherichia fergusonii ATCC 35469 arginine exporter protein YP_002383956.1 2920188 R 585054 CDS YP_002383957.1 218550166 7120541 complement(2920962..2921822) 1 NC_011740.1 participates in the regulation of osmotic pressure changes within the cel; mechanosensitive channel MscS 2921822 mscS 7120541 mscS Escherichia fergusonii ATCC 35469 mechanosensitive channel MscS YP_002383957.1 2920962 R 585054 CDS YP_002383958.1 218550167 7123784 complement(2922180..2923259) 1 NC_011740.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 2923259 fbaA 7123784 fbaA Escherichia fergusonii ATCC 35469 fructose-bisphosphate aldolase YP_002383958.1 2922180 R 585054 CDS YP_002383959.1 218550168 7119990 complement(2923349..2924512) 1 NC_011740.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 2924512 pgk 7119990 pgk Escherichia fergusonii ATCC 35469 phosphoglycerate kinase YP_002383959.1 2923349 R 585054 CDS YP_002383960.1 218550169 7122588 complement(2924562..2925581) 1 NC_011740.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate; erythrose 4-phosphate dehydrogenase 2925581 epd 7122588 epd Escherichia fergusonii ATCC 35469 erythrose 4-phosphate dehydrogenase YP_002383960.1 2924562 R 585054 CDS YP_002383961.1 218550170 7122955 complement(2925866..2926579) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; fructose transport system kinase 2926579 frcK 7122955 frcK Escherichia fergusonii ATCC 35469 fructose transport system kinase YP_002383961.1 2925866 R 585054 CDS YP_002383962.1 218550171 7119842 complement(2926576..2927085) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator 2927085 yggD 7119842 yggD Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YP_002383962.1 2926576 R 585054 CDS YP_002383963.1 218550172 7123600 complement(2927107..2928072) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; fructose-1,6-bisphosphatase II-like protein 2928072 yggF 7123600 yggF Escherichia fergusonii ATCC 35469 fructose-1,6-bisphosphatase II-like protein YP_002383963.1 2927107 R 585054 CDS YP_002383964.1 218550173 7119844 complement(2928069..2929346) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; dehydrogenase 2929346 yggP 7119844 yggP Escherichia fergusonii ATCC 35469 dehydrogenase YP_002383964.1 2928069 R 585054 CDS YP_002383965.1 218550174 7119849 complement(2929361..2930749) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 8353127; Product type t : transporter; PTS system mannitol-specific transporter subunit IIBC 2930749 cmtA 7119849 cmtA Escherichia fergusonii ATCC 35469 PTS system mannitol-specific transporter subunit IIBC YP_002383965.1 2929361 R 585054 CDS YP_002383966.1 218550175 7123773 complement(2930777..2931220) 1 NC_011740.1 TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein; mannitol phosphotransferase subunit EIIA 2931220 cmtB 7123773 cmtB Escherichia fergusonii ATCC 35469 mannitol phosphotransferase subunit EIIA YP_002383966.1 2930777 R 585054 CDS YP_002383967.1 218550176 7123774 2931588..2932505 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; membrane protease 2932505 7123774 EFER_2866 Escherichia fergusonii ATCC 35469 membrane protease YP_002383967.1 2931588 D 585054 CDS YP_002383968.1 218550177 7120395 complement(2932551..2934542) 1 NC_011740.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 2934542 tktA 7120395 tktA Escherichia fergusonii ATCC 35469 transketolase YP_002383968.1 2932551 R 585054 CDS YP_002383969.1 218550178 7122134 2934585..2934749 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2934749 7122134 EFER_2868 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383969.1 2934585 D 585054 CDS YP_002383970.1 218550179 7120396 2934820..2935578 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1310091; Product type pe : enzyme; peptidase 2935578 yggG 7120396 yggG Escherichia fergusonii ATCC 35469 peptidase YP_002383970.1 2934820 D 585054 CDS YP_002383971.1 218550180 7119845 complement(2935664..2937226) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2937226 7119845 EFER_2870 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383971.1 2935664 R 585054 CDS YP_002383972.1 218550181 7123695 complement(2937376..2938296) 1 NC_011740.1 catalyzes the formation of putrescine from agmatine; agmatinase 2938296 speB 7123695 speB Escherichia fergusonii ATCC 35469 agmatinase YP_002383972.1 2937376 R 585054 CDS YP_002383973.1 218550182 7121802 complement(2938487..2939644) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase 2939644 7121802 EFER_2872 Escherichia fergusonii ATCC 35469 2-dehydro-3-deoxy-6-phosphogalactonate aldolase YP_002383973.1 2938487 R 585054 CDS YP_002383974.1 218550183 7120740 complement(2940297..2940452) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2940452 7120740 EFER_2875 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383974.1 2940297 R 585054 CDS YP_002383975.1 218550184 7120397 2940961..2944998 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type pm : membrane component; AidA-I adhesin-like protein 2944998 7120397 EFER_2876 Escherichia fergusonii ATCC 35469 AidA-I adhesin-like protein YP_002383975.1 2940961 D 585054 CDS YP_002383976.1 218550185 7120398 2945230..2945493 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2945493 7120398 EFER_2877 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383976.1 2945230 D 585054 CDS YP_002383977.1 218550186 7120399 complement(2945537..2947513) 1 NC_011740.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase 2947513 speA 7120399 speA Escherichia fergusonii ATCC 35469 arginine decarboxylase YP_002383977.1 2945537 R 585054 CDS YP_002383978.1 218550187 7123927 2947615..2947980 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2947980 7123927 EFER_2879 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383978.1 2947615 D 585054 CDS YP_002383979.1 218550188 7120400 complement(2947997..2948266) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2948266 yqgD 7120400 yqgD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383979.1 2947997 R 585054 CDS YP_002383980.1 218550189 7119725 2948307..2949461 1 NC_011740.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 2949461 metK 7119725 metK Escherichia fergusonii ATCC 35469 S-adenosylmethionine synthetase YP_002383980.1 2948307 D 585054 CDS YP_002383981.1 218550190 7120922 2949897..2951291 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9182541; Product type t : transporter; D-galactose transporter 2951291 galP 7120922 galP Escherichia fergusonii ATCC 35469 D-galactose transporter YP_002383981.1 2949897 D 585054 CDS YP_002383982.1 218550191 7120168 2951368..2951865 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 7984428, 8113204; hypothetical protein 2951865 sprT 7120168 sprT Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383982.1 2951368 D 585054 CDS YP_002383983.1 218550192 7121811 2951960..2952667 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 72060411, 92335461, 4955462, 7867949, 8113204; Product type e : enzyme; DNA-specific endonuclease I 2952667 endA 7121811 endA Escherichia fergusonii ATCC 35469 DNA-specific endonuclease I YP_002383983.1 2951960 D 585054 CDS YP_002383984.1 218550193 7122948 2952747..2953478 1 NC_011740.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 2953478 yggJ 7122948 yggJ Escherichia fergusonii ATCC 35469 16S ribosomal RNA methyltransferase RsmE YP_002383984.1 2952747 D 585054 CDS YP_002383985.1 218550194 7123601 2953491..2954441 1 NC_011740.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 2954441 gshB 7123601 gshB Escherichia fergusonii ATCC 35469 glutathione synthetase YP_002383985.1 2953491 D 585054 CDS YP_002383986.1 218550195 7123189 2954550..2955113 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2955113 yqgE 7123189 yqgE Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383986.1 2954550 D 585054 CDS YP_002383987.1 218550196 7123585 2955113..2955529 1 NC_011740.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 2955529 yqgF 7123585 yqgF Escherichia fergusonii ATCC 35469 Holliday junction resolvase-like protein YP_002383987.1 2955113 D 585054 CDS YP_002383988.1 218550197 7119726 complement(2955536..2956516) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1676385; Product type t : transporter; transporter 2956516 yggR 7119726 yggR Escherichia fergusonii ATCC 35469 transporter YP_002383988.1 2955536 R 585054 CDS YP_002383989.1 218550198 7119850 2956534..2957238 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 2957238 yggS 7119850 yggS Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383989.1 2956534 D 585054 CDS YP_002383990.1 218550199 7123602 2957256..2957822 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2957822 yggT 7123602 yggT Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383990.1 2957256 D 585054 CDS YP_002383991.1 218550200 7119851 2957819..2958109 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12975589; hypothetical protein 2958109 yggU 7119851 yggU Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383991.1 2957819 D 585054 CDS YP_002383992.1 218550201 7119852 2958117..2958710 1 NC_011740.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 2958710 yggV 7119852 yggV Escherichia fergusonii ATCC 35469 deoxyribonucleotide triphosphate pyrophosphatase YP_002383992.1 2958117 D 585054 CDS YP_002383993.1 218550202 7119853 2958703..2959839 1 NC_011740.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 2959839 yggW 7119853 yggW Escherichia fergusonii ATCC 35469 coproporphyrinogen III oxidase YP_002383993.1 2958703 D 585054 CDS YP_002383994.1 218550203 7119854 2960153..2961139 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; c4-dicarboxylate transport system binding protein 2961139 7119854 EFER_2895 Escherichia fergusonii ATCC 35469 c4-dicarboxylate transport system binding protein YP_002383994.1 2960153 D 585054 CDS YP_002383995.1 218550204 7120401 2961175..2961687 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; TRAP-type C4-dicarboxylate transport system, small permease 2961687 7120401 EFER_2896 Escherichia fergusonii ATCC 35469 TRAP-type C4-dicarboxylate transport system, small permease YP_002383995.1 2961175 D 585054 CDS YP_002383996.1 218550205 7120402 2961687..2962988 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type t : transporter; c4-dicarboxylate permease 2962988 ygiK 7120402 ygiK Escherichia fergusonii ATCC 35469 c4-dicarboxylate permease YP_002383996.1 2961687 D 585054 CDS YP_002383997.1 218550206 7119866 complement(2963092..2964096) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2964096 7119866 EFER_2898 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383997.1 2963092 R 585054 CDS YP_002383998.1 218550207 7120403 complement(2964213..2965259) 1 NC_011740.1 catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis; L-asparaginase II 2965259 ansB 7120403 ansB Escherichia fergusonii ATCC 35469 L-asparaginase II YP_002383998.1 2964213 R 585054 CDS YP_002383999.1 218550208 7120519 complement(2965445..2966164) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11274153; hypothetical protein 2966164 yggN 7120519 yggN Escherichia fergusonii ATCC 35469 hypothetical protein YP_002383999.1 2965445 R 585054 CDS YP_002384000.1 218550209 7119848 complement(2966217..2966543) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2966543 yggL 7119848 yggL Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384000.1 2966217 R 585054 CDS YP_002384001.1 218550210 7119847 complement(2966543..2967262) 1 NC_011740.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 2967262 trmB 7119847 trmB Escherichia fergusonii ATCC 35469 tRNA (guanine-N(7)-)-methyltransferase YP_002384001.1 2966543 R 585054 CDS YP_002384002.1 218550211 7119846 2967423..2968475 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14730969, 20187555, 20316830, 20580749, 21438845, 90046892, 92409600, 9801309, 2001994, 2197596, 9846876; Product type e : enzyme; adenine DNA glycosylase 2968475 mutY 7119846 mutY Escherichia fergusonii ATCC 35469 adenine DNA glycosylase YP_002384002.1 2967423 D 585054 CDS YP_002384003.1 218550212 7123198 2968503..2968778 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14594836, 10493123, 9298646, 9868784; Product type f : factor; hypothetical protein 2968778 yggX 7123198 yggX Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384003.1 2968503 D 585054 CDS YP_002384004.1 218550213 7123060 2968843..2969922 1 NC_011740.1 Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 2969922 mltC 7123060 mltC Escherichia fergusonii ATCC 35469 murein transglycosylase C YP_002384004.1 2968843 D 585054 CDS YP_002384005.1 218550214 7123779 complement(2969945..2970088) 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 2970088 7123779 EFER_2906 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384005.1 2969945 R 585054 CDS YP_002384006.1 218550215 7123153 2970150..2971406 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88029453, 90323001, 3311747; Product type t : transporter; nucleoside transporter 2971406 nupG 7123153 nupG Escherichia fergusonii ATCC 35469 nucleoside transporter YP_002384006.1 2970150 D 585054 CDS YP_002384007.1 218550216 7119683 complement(2971457..2973598) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87222180, 87260820; Product type e : enzyme; ornithine decarboxylase 2973598 speC 7119683 speC Escherichia fergusonii ATCC 35469 ornithine decarboxylase YP_002384007.1 2971457 R 585054 CDS YP_002384008.1 218550217 7121803 2973966..2974706 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2974706 yqgA 7121803 yqgA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384008.1 2973966 D 585054 CDS YP_002384009.1 218550218 7123584 2974800..2974949 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2974949 7123584 EFER_2910 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384009.1 2974800 D 585054 CDS YP_002384010.1 218550219 7120044 2975950..2980521 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 1644747; Product type lp : lipoprotein; inner membrane lipoprotein 2980521 yghJ 7120044 yghJ Escherichia fergusonii ATCC 35469 inner membrane lipoprotein YP_002384010.1 2975950 D 585054 CDS YP_002384011.1 218550220 7119859 2980677..2981486 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98175453; Product type e : enzyme; bifunctional prepilin leader peptidase and methylase 2981486 pppA 7119859 pppA Escherichia fergusonii ATCC 35469 bifunctional prepilin leader peptidase and methylase YP_002384011.1 2980677 D 585054 CDS YP_002384012.1 218550221 7120116 2981552..2981962 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2981962 yghG 7120116 yghG Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384012.1 2981552 D 585054 CDS YP_002384013.1 218550222 7119858 2981978..2982931 1 NC_011740.1 part of the general (type II) secretion pathway (GSP), a signal sequence-dependent process responsible for protein export; involved in trans-location of exoproteins from the cytoplasm to the periplasm; type II secretion protein GspC 2982931 yghF 7119858 yghF Escherichia fergusonii ATCC 35469 type II secretion protein GspC YP_002384013.1 2981978 D 585054 CDS YP_002384014.1 218550223 7123603 2982961..2985021 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type t : transporter; general secretion pathway protein D 2985021 epsD 7123603 epsD Escherichia fergusonii ATCC 35469 general secretion pathway protein D YP_002384014.1 2982961 D 585054 CDS YP_002384015.1 218550224 7122956 2985021..2986514 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type t : transporter; general secretion pathway protein E 2986514 epsE 7122956 epsE Escherichia fergusonii ATCC 35469 general secretion pathway protein E YP_002384015.1 2985021 D 585054 CDS YP_002384016.1 218550225 7122957 2986514..2987737 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type t : transporter; General secretion pathway protein F 2987737 epsF 7122957 epsF Escherichia fergusonii ATCC 35469 General secretion pathway protein F YP_002384016.1 2986514 D 585054 CDS YP_002384017.1 218550226 7122958 2987727..2988209 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; general secretion pathway protein G 2988209 7122958 EFER_2918 Escherichia fergusonii ATCC 35469 general secretion pathway protein G YP_002384017.1 2987727 D 585054 CDS YP_002384018.1 218550227 7120405 2988213..2988776 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2988776 7120405 EFER_2919 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384018.1 2988213 D 585054 CDS YP_002384019.1 218550228 7120406 2988773..2989144 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; type II secretion protein 2989144 7120406 EFER_2920 Escherichia fergusonii ATCC 35469 type II secretion protein YP_002384019.1 2988773 D 585054 CDS YP_002384020.1 218550229 7120407 2989141..2989746 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2989746 7120407 EFER_2921 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384020.1 2989141 D 585054 CDS YP_002384021.1 218550230 7123154 2989743..2990720 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; type II secretion protein 2990720 7123154 EFER_2922 Escherichia fergusonii ATCC 35469 type II secretion protein YP_002384021.1 2989743 D 585054 CDS YP_002384022.1 218550231 7123155 2990717..2991895 1 NC_011740.1 similar to general secretory pathway protein L; GspL-like protein 2991895 yghE 7123155 yghE Escherichia fergusonii ATCC 35469 GspL-like protein YP_002384022.1 2990717 D 585054 CDS YP_002384023.1 218550232 7119857 2991897..2992433 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; general secretion pathway protein YghD 2992433 yghD 7119857 yghD Escherichia fergusonii ATCC 35469 general secretion pathway protein YghD YP_002384023.1 2991897 D 585054 CDS YP_002384024.1 218550233 7123061 2992824..2993612 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; hypothetical protein 2993612 yafT 7123061 yafT Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384024.1 2992824 D 585054 CDS YP_002384025.1 218550234 7122423 complement(2994435..2994788) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2994788 7122423 EFER_2926 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384025.1 2994435 R 585054 CDS YP_002384026.1 218550235 7120408 complement(2994993..2995280) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; global regulatory protein 2995280 7120408 EFER_2927 Escherichia fergusonii ATCC 35469 global regulatory protein YP_002384026.1 2994993 R 585054 CDS YP_002384027.1 218550236 7120409 complement(2995926..2996285) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2996285 7120409 EFER_2928 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384027.1 2995926 R 585054 CDS YP_002384028.1 218550237 7120410 complement(2996511..2996876) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2996876 7120410 EFER_2929 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384028.1 2996511 R 585054 CDS YP_002384029.1 218550238 7120411 complement(2997489..2999348) 1 NC_011740.1 catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction; bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase 2999348 gss 7120411 gss Escherichia fergusonii ATCC 35469 bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase YP_002384029.1 2997489 R 585054 CDS YP_002384030.1 218550239 7120621 2999699..3000526 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 6317653, 2536924; Product type r : regulator; envelope protein 3000526 envY 7120621 envY Escherichia fergusonii ATCC 35469 envelope protein YP_002384030.1 2999699 D 585054 CDS YP_002384031.1 218550240 7122953 3000596..3001462 1 NC_011740.1 YghU; B2989; one of eight glutathione transferase proteins from E. coli; glutathione S-transferase 3001462 yghU 7122953 yghU Escherichia fergusonii ATCC 35469 glutathione S-transferase YP_002384031.1 3000596 D 585054 CDS YP_002384032.1 218550241 7119860 complement(3001532..3001780) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92215587, 94292472, 8021226; Product type pf : factor; hydrogenase 2 accessory protein HypG 3001780 hybG 7119860 hybG Escherichia fergusonii ATCC 35469 hydrogenase 2 accessory protein HypG YP_002384032.1 3001532 R 585054 CDS YP_002384033.1 218550242 7120700 complement(3001793..3002134) 1 NC_011740.1 plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein HybF 3002134 hybF 7120700 hybF Escherichia fergusonii ATCC 35469 hydrogenase nickel incorporation protein HybF YP_002384033.1 3001793 R 585054 CDS YP_002384034.1 218550243 7120699 complement(3002127..3002615) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94292472, 8021226; Product type f : factor; hydrogenase 2-specific chaperone 3002615 hybE 7120699 hybE Escherichia fergusonii ATCC 35469 hydrogenase 2-specific chaperone YP_002384034.1 3002127 R 585054 CDS YP_002384035.1 218550244 7123747 complement(3002608..3003102) 1 NC_011740.1 protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC); hydrogenase 2 maturation endopeptidase 3003102 hybD 7123747 hybD Escherichia fergusonii ATCC 35469 hydrogenase 2 maturation endopeptidase YP_002384035.1 3002608 R 585054 CDS YP_002384036.1 218550245 7123448 complement(3003102..3004805) 1 NC_011740.1 involved in hydrogen uptake; hydrogenase 2 large subunit 3004805 hybC 7123448 hybC Escherichia fergusonii ATCC 35469 hydrogenase 2 large subunit YP_002384036.1 3003102 R 585054 CDS YP_002384037.1 218550246 7122241 complement(3004802..3005980) 1 NC_011740.1 HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits; hydrogenase 2 b cytochrome subunit 3005980 hybB 7122241 hybB Escherichia fergusonii ATCC 35469 hydrogenase 2 b cytochrome subunit YP_002384037.1 3004802 R 585054 CDS YP_002384038.1 218550247 7122240 complement(3005970..3006956) 1 NC_011740.1 Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; hydrogenase 2 protein HybA 3006956 hybA 7122240 hybA Escherichia fergusonii ATCC 35469 hydrogenase 2 protein HybA YP_002384038.1 3005970 R 585054 CDS YP_002384039.1 218550248 7123447 complement(3006959..3008077) 1 NC_011740.1 involved in hydrogen uptake; hydrogenase 2 small subunit 3008077 hybO 7123447 hybO Escherichia fergusonii ATCC 35469 hydrogenase 2 small subunit YP_002384039.1 3006959 R 585054 CDS YP_002384040.1 218550249 7120701 complement(3008266..3008670) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3008670 yghW 7120701 yghW Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384040.1 3008266 R 585054 CDS YP_002384041.1 218550250 7119861 complement(3008667..3009593) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3009593 7119861 EFER_2942 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384041.1 3008667 R 585054 CDS YP_002384042.1 218550251 7123697 3009711..3010751 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12583903; Product type e : enzyme; aldo-keto reductase 3010751 yghZ 7123697 yghZ Escherichia fergusonii ATCC 35469 aldo-keto reductase YP_002384042.1 3009711 D 585054 CDS YP_002384043.1 218550252 7123604 complement(3010791..3011285) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3011285 yqhA 7123604 yqhA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384043.1 3010791 R 585054 CDS YP_002384044.1 218550253 7119727 3011476..3012360 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; oxidoreductase 3012360 yghA 7119727 yghA Escherichia fergusonii ATCC 35469 oxidoreductase YP_002384044.1 3011476 D 585054 CDS YP_002384045.1 218550254 7119855 complement(3012399..3012824) 1 NC_011740.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbD 3012824 exbD 7119855 exbD Escherichia fergusonii ATCC 35469 biopolymer transport protein ExbD YP_002384045.1 3012399 R 585054 CDS YP_002384046.1 218550255 7119974 complement(3012831..3013565) 1 NC_011740.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbB 3013565 exbB 7119974 exbB Escherichia fergusonii ATCC 35469 biopolymer transport protein ExbB YP_002384046.1 3012831 R 585054 CDS YP_002384047.1 218550256 7123082 3013817..3015004 1 NC_011740.1 catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 3015004 metC 7123082 metC Escherichia fergusonii ATCC 35469 cystathionine beta-lyase YP_002384047.1 3013817 D 585054 CDS YP_002384048.1 218550257 7120916 3015144..3015803 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3015803 yghB 7120916 yghB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384048.1 3015144 D 585054 CDS YP_002384049.1 218550258 7119856 complement(3015841..3016761) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator 3016761 yqhC 7119856 yqhC Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YP_002384049.1 3015841 R 585054 CDS YP_002384050.1 218550259 7119728 3016933..3018096 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15327949; Product type e : enzyme; alcohol dehydrogenase 3018096 yqhD 7119728 yqhD Escherichia fergusonii ATCC 35469 alcohol dehydrogenase YP_002384050.1 3016933 D 585054 CDS YP_002384051.1 218550260 7119729 3018200..3019027 1 NC_011740.1 methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; 2,5-diketo-D-gluconate reductase A 3019027 dkgA 7119729 dkgA Escherichia fergusonii ATCC 35469 2,5-diketo-D-gluconate reductase A YP_002384051.1 3018200 D 585054 CDS YP_002384052.1 218550261 7122904 3019211..3020665 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; sodium:sulfate symporter 3020665 7122904 EFER_2953 Escherichia fergusonii ATCC 35469 sodium:sulfate symporter YP_002384052.1 3019211 D 585054 CDS YP_002384053.1 218550262 7123698 3020782..3021042 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; outer membrane lipoprotein 3021042 yqhH 7123698 yqhH Escherichia fergusonii ATCC 35469 outer membrane lipoprotein YP_002384053.1 3020782 D 585054 CDS YP_002384054.1 218550263 7119730 complement(3021093..3023312) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3023312 ygiQ 7119730 ygiQ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384054.1 3021093 R 585054 CDS YP_002384055.1 218550264 7123062 3023526..3024314 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; regulator 3024314 7123062 EFER_2956 Escherichia fergusonii ATCC 35469 regulator YP_002384055.1 3023526 D 585054 CDS YP_002384056.1 218550265 7120412 3024639..3026111 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; fructuronate reductase 3026111 7120412 EFER_2957 Escherichia fergusonii ATCC 35469 fructuronate reductase YP_002384056.1 3024639 D 585054 CDS YP_002384057.1 218550266 7120413 3026108..3027124 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; L-threonine 3-dehydrogenase 3027124 7120413 EFER_2958 Escherichia fergusonii ATCC 35469 L-threonine 3-dehydrogenase YP_002384057.1 3026108 D 585054 CDS YP_002384058.1 218550267 7120414 3027135..3028145 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Ureidoglycolate dehydrogenase 3028145 7120414 EFER_2959 Escherichia fergusonii ATCC 35469 Ureidoglycolate dehydrogenase YP_002384058.1 3027135 D 585054 CDS YP_002384059.1 218550268 7120415 3028218..3029201 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; c4-dicarboxylate transport system binding protein; secreted protein 3029201 7120415 EFER_2960 Escherichia fergusonii ATCC 35469 c4-dicarboxylate transport system binding protein; secreted protein YP_002384059.1 3028218 D 585054 CDS YP_002384060.1 218550269 7123699 3029243..3029725 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; TRAP-type C4-dicarboxylate transport system, small permease 3029725 7123699 EFER_2961 Escherichia fergusonii ATCC 35469 TRAP-type C4-dicarboxylate transport system, small permease YP_002384060.1 3029243 D 585054 CDS YP_002384061.1 218550270 7120416 3029694..3031040 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type t : transporter; c4-dicarboxylate permease 3031040 ygiK 7120416 ygiK Escherichia fergusonii ATCC 35469 c4-dicarboxylate permease YP_002384061.1 3029694 D 585054 CDS YP_002384062.1 218550271 7119867 complement(3031254..3032666) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88314889, 1557036, 9298646; Product type r : regulator; repressor protein for FtsI 3032666 sufI 7119867 sufI Escherichia fergusonii ATCC 35469 repressor protein for FtsI YP_002384062.1 3031254 R 585054 CDS YP_002384063.1 218550272 7123404 complement(3032735..3033472) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92212294, 1557036; Product type e : enzyme; 1-acyl-sn-glycerol-3-phosphate acyltransferase 3033472 plsC 7123404 plsC Escherichia fergusonii ATCC 35469 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_002384063.1 3032735 R 585054 CDS YP_002384064.1 218550273 7120088 complement(3033724..3035982) 1 NC_011740.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 3035982 parC 7120088 parC Escherichia fergusonii ATCC 35469 DNA topoisomerase IV subunit A YP_002384064.1 3033724 R 585054 CDS YP_002384065.1 218550274 7122556 complement(3036102..3036554) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9298646; hypothetical protein 3036554 ygiW 7122556 ygiW Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384065.1 3036102 R 585054 CDS YP_002384066.1 218550275 7119870 3036645..3037304 1 NC_011740.1 response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes; DNA-binding transcriptional regulator QseB 3037304 qseB 7119870 qseB Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator QseB YP_002384066.1 3036645 D 585054 CDS YP_002384067.1 218550276 7122340 3037301..3038656 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11929534, 15919996; Product type r : regulator; sensor protein QseC 3038656 qseC 7122340 qseC Escherichia fergusonii ATCC 35469 sensor protein QseC YP_002384067.1 3037301 D 585054 CDS YP_002384068.1 218550277 7124025 3038759..3039340 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96004656, 96217538; Product type c : carrier; NADPH quinone reductase 3039340 mdaB 7124025 mdaB Escherichia fergusonii ATCC 35469 NADPH quinone reductase YP_002384068.1 3038759 D 585054 CDS YP_002384069.1 218550278 7121239 3039371..3039685 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10493123, 9298646, 9600841, 9868784; Product type e : enzyme; quinol monooxygenase 3039685 ygiN 7121239 ygiN Escherichia fergusonii ATCC 35469 quinol monooxygenase YP_002384069.1 3039371 D 585054 CDS YP_002384070.1 218550279 7119869 complement(3039733..3041625) 1 NC_011740.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 3041625 parE 7119869 parE Escherichia fergusonii ATCC 35469 DNA topoisomerase IV subunit B YP_002384070.1 3039733 R 585054 CDS YP_002384071.1 218550280 7122557 complement(3041654..3042235) 1 NC_011740.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YqiA 3042235 yqiA 7122557 yqiA Escherichia fergusonii ATCC 35469 esterase YqiA YP_002384071.1 3041654 R 585054 CDS YP_002384072.1 218550281 7119731 complement(3042235..3043062) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96411758; Product type e : enzyme; cyclic 3',5'-adenosine monophosphate phosphodiesterase 3043062 cpdA 7119731 cpdA Escherichia fergusonii ATCC 35469 cyclic 3',5'-adenosine monophosphate phosphodiesterase YP_002384072.1 3042235 R 585054 CDS YP_002384073.1 218550282 7124104 complement(3043087..3043509) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 3043509 yqiB 7124104 yqiB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384073.1 3043087 R 585054 CDS YP_002384074.1 218550283 7123586 complement(3043509..3044138) 1 NC_011740.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose pyrophosphatase NudF 3044138 nudF 7123586 nudF Escherichia fergusonii ATCC 35469 ADP-ribose pyrophosphatase NudF YP_002384074.1 3043509 R 585054 CDS YP_002384075.1 218550284 7119671 3044338..3045819 1 NC_011740.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell; outer membrane channel protein 3045819 tolC 7119671 tolC Escherichia fergusonii ATCC 35469 outer membrane channel protein YP_002384075.1 3044338 D 585054 CDS YP_002384076.1 218550285 7122141 3045819..3046076 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3046076 ygiA 7122141 ygiA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384076.1 3045819 D 585054 CDS YP_002384077.1 218550286 7119862 3046060..3046635 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3046635 ygiB 7119862 ygiB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384077.1 3046060 D 585054 CDS YP_002384078.1 218550287 7119863 3046641..3047801 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 3047801 ygiC 7119863 ygiC Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384078.1 3046641 D 585054 CDS YP_002384079.1 218550288 7119864 3048324..3050120 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8887346, 11534764; Product type e : enzyme; arylsulfate sulfotransferase 3050120 assT 7119864 assT Escherichia fergusonii ATCC 35469 arylsulfate sulfotransferase YP_002384079.1 3048324 D 585054 CDS YP_002384080.1 218550289 7120573 3050136..3050804 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8887346, 10600454; Product type e : enzyme; Thiol:disulfide interchange protein dsbA 3050804 dsbA 7120573 dsbA Escherichia fergusonii ATCC 35469 Thiol:disulfide interchange protein dsbA YP_002384080.1 3050136 D 585054 CDS YP_002384081.1 218550290 7122921 3050819..3051490 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10600454; Product type pe : enzyme; disulfide oxidoreductase 3051490 7122921 EFER_2982 Escherichia fergusonii ATCC 35469 disulfide oxidoreductase YP_002384081.1 3050819 D 585054 CDS YP_002384082.1 218550291 7120417 complement(3051538..3052416) 1 NC_011740.1 seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine; hypothetical protein 3052416 zupT 7120417 zupT Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384082.1 3051538 R 585054 CDS YP_002384083.1 218550292 7123421 3052468..3053241 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11790762, 1314093; Product type t : transporter; zinc transporter ZupT 3053241 ygiE 7123421 ygiE Escherichia fergusonii ATCC 35469 zinc transporter ZupT YP_002384083.1 3052468 D 585054 CDS YP_002384084.1 218550293 7119865 complement(3053307..3053489) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3053489 7119865 EFER_2985 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384084.1 3053307 R 585054 CDS YP_002384085.1 218550294 7120418 3054045..3054608 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; fimbrial protein 3054608 ygiL 7120418 ygiL Escherichia fergusonii ATCC 35469 fimbrial protein YP_002384085.1 3054045 D 585054 CDS YP_002384086.1 218550295 7119868 3054695..3057217 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; outer membrane usher protein 3057217 yqiG 7119868 yqiG Escherichia fergusonii ATCC 35469 outer membrane usher protein YP_002384086.1 3054695 D 585054 CDS YP_002384087.1 218550296 7123037 3057224..3057973 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; periplasmic pilin chaperone 3057973 yqiH 7123037 yqiH Escherichia fergusonii ATCC 35469 periplasmic pilin chaperone YP_002384087.1 3057224 D 585054 CDS YP_002384088.1 218550297 7123587 3057970..3059013 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3059013 7123587 EFER_2989 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384088.1 3057970 D 585054 CDS YP_002384089.1 218550298 7120419 complement(3059067..3059720) 1 NC_011740.1 DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase 3059720 ribB 7120419 ribB Escherichia fergusonii ATCC 35469 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_002384089.1 3059067 R 585054 CDS YP_002384090.1 218550299 7121405 3060036..3060392 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3060392 yqiC 7121405 yqiC Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384090.1 3060036 D 585054 CDS YP_002384091.1 218550300 7119732 complement(3060562..3060768) 1 NC_011740.1 Involved in glycogen synthesis. May be involved in glycogen priming; glycogen synthesis protein GlgS 3060768 glgS 7119732 glgS Escherichia fergusonii ATCC 35469 glycogen synthesis protein GlgS YP_002384091.1 3060562 R 585054 CDS YP_002384092.1 218550301 7120188 3061019..3061648 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15919996; Product type pm : membrane component; Inner membrane protein yqiJ 3061648 yqiJ 7120188 yqiJ Escherichia fergusonii ATCC 35469 Inner membrane protein yqiJ YP_002384092.1 3061019 D 585054 CDS YP_002384093.1 218550302 7119733 3061679..3063340 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3063340 yqiK 7119733 yqiK Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384093.1 3061679 D 585054 CDS YP_002384094.1 218550303 7121182 3063675..3063944 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3063944 7121182 EFER_2995 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384094.1 3063675 D 585054 CDS YP_002384095.1 218550304 7121180 complement(3064510..3065943) 1 NC_011740.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase 3065943 rfaE 7121180 rfaE Escherichia fergusonii ATCC 35469 bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase YP_002384095.1 3064510 R 585054 CDS YP_002384096.1 218550305 7123311 complement(3065991..3068831) 1 NC_011740.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 3068831 glnE 7123311 glnE Escherichia fergusonii ATCC 35469 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase YP_002384096.1 3065991 R 585054 CDS YP_002384097.1 218550306 7120196 complement(3068854..3070155) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8412694; Product type pe : enzyme; adenylate cyclase 3070155 ygiF 7120196 ygiF Escherichia fergusonii ATCC 35469 adenylate cyclase YP_002384097.1 3068854 R 585054 CDS YP_002384098.1 218550307 7123605 complement(3070172..3070378) 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 3070378 7123605 EFER_2999 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384098.1 3070172 R 585054 CDS YP_002384099.1 218550308 7120421 3070397..3071017 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11274153; Product type pr : regulator; signal transduction protein 3071017 htrG 7120421 htrG Escherichia fergusonii ATCC 35469 signal transduction protein YP_002384099.1 3070397 D 585054 CDS YP_002384100.1 218550309 7122233 3071081..3072319 1 NC_011740.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 3072319 cca 7122233 cca Escherichia fergusonii ATCC 35469 multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase YP_002384100.1 3071081 D 585054 CDS YP_002384101.1 218550310 7120864 complement(3072400..3073221) 1 NC_011740.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 3073221 bacA 7120864 bacA Escherichia fergusonii ATCC 35469 undecaprenyl pyrophosphate phosphatase YP_002384101.1 3072400 R 585054 CDS YP_002384102.1 218550311 7123355 complement(3073312..3073680) 1 NC_011740.1 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin; bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase 3073680 folB 7123355 folB Escherichia fergusonii ATCC 35469 bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase YP_002384102.1 3073312 R 585054 CDS YP_002384103.1 218550312 7123569 3073786..3074403 1 NC_011740.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 3074403 plsY 7123569 plsY Escherichia fergusonii ATCC 35469 glycerol-3-phosphate acyltransferase PlsY YP_002384103.1 3073786 D 585054 CDS YP_002384104.1 218550313 7123101 complement(3074449..3075462) 1 NC_011740.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 3075462 gcp 7123101 gcp Escherichia fergusonii ATCC 35469 DNA-binding/iron metalloprotein/AP endonuclease YP_002384104.1 3074449 R 585054 CDS YP_002384105.1 218550314 7120177 3075700..3075915 1 NC_011740.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 3075915 rpsU 7120177 rpsU Escherichia fergusonii ATCC 35469 30S ribosomal protein S21 YP_002384105.1 3075700 D 585054 CDS YP_002384106.1 218550315 7121140 3076027..3077772 1 NC_011740.1 synthesizes RNA primers at the replication forks; DNA primase 3077772 dnaG 7121140 dnaG Escherichia fergusonii ATCC 35469 DNA primase YP_002384106.1 3076027 D 585054 CDS YP_002384107.1 218550316 7122911 3077967..3079808 1 NC_011740.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 3079808 rpoD 7122911 rpoD Escherichia fergusonii ATCC 35469 RNA polymerase sigma factor RpoD YP_002384107.1 3077967 D 585054 CDS YP_002384108.1 218550317 7123811 3079868..3080431 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3080431 7123811 EFER_3009 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384108.1 3079868 D 585054 CDS YP_002384109.1 218550318 7123156 complement(3080488..3080994) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20412902, 99453007, 6269063, 7567469, 8878487, 9489705; Product type e : enzyme; G/U mismatch-specific DNA glycosylase 3080994 ygjF 7123156 ygjF Escherichia fergusonii ATCC 35469 G/U mismatch-specific DNA glycosylase YP_002384109.1 3080488 R 585054 CDS YP_002384110.1 218550319 7120045 complement(3081311..3083278) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2531290, 8041620, 9278503, 2140572; Product type pf : factor; Selenocysteine-specific elongation factor 3083278 7120045 EFER_3011 Escherichia fergusonii ATCC 35469 Selenocysteine-specific elongation factor YP_002384110.1 3081311 R 585054 CDS YP_002384111.1 218550320 7120422 complement(3083232..3083627) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; GrdX protein 3083627 7120422 EFER_3012 Escherichia fergusonii ATCC 35469 GrdX protein YP_002384111.1 3083232 R 585054 CDS YP_002384112.1 218550321 7120423 complement(3083673..3083897) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10091582, 8529639; Product type e : enzyme; glycine reductase complex component B subunit gamma 3083897 7120423 EFER_3013 Escherichia fergusonii ATCC 35469 glycine reductase complex component B subunit gamma YP_002384112.1 3083673 R 585054 CDS YP_002384113.1 218550322 7120424 complement(3083925..3084971) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10091582, 8529639; Product type e : enzyme; glycine reductase complex component B subunit gamma 3084971 7120424 EFER_3014 Escherichia fergusonii ATCC 35469 glycine reductase complex component B subunit gamma YP_002384113.1 3083925 R 585054 CDS YP_002384114.1 218550323 7120425 complement(3084985..3086274) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10091582, 8529639; Product type e : enzyme; glycine reductase complex component B subunits alpha/beta 3086274 7120425 EFER_3015 Escherichia fergusonii ATCC 35469 glycine reductase complex component B subunits alpha/beta YP_002384114.1 3084985 R 585054 CDS YP_002384115.1 218550324 7123157 complement(3086285..3087547) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11737196, 1587286; Product type e : enzyme; glycine/sarcosine/betaine reductase complex component C subunit alpha 3087547 7123157 EFER_3016 Escherichia fergusonii ATCC 35469 glycine/sarcosine/betaine reductase complex component C subunit alpha YP_002384115.1 3086285 R 585054 CDS YP_002384116.1 218550325 7123158 complement(3087405..3088964) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8223622, 1587286; Product type e : enzyme; glycine/sarcosine/betaine reductase complex component C subunit beta 3088964 7123158 EFER_3017 Escherichia fergusonii ATCC 35469 glycine/sarcosine/betaine reductase complex component C subunit beta YP_002384116.1 3087405 R 585054 CDS YP_002384117.1 218550326 7120426 complement(3088985..3089314) 1 NC_011740.1 GrdA accepts a carboxymethylselenoether from protein B and transfers it to protein C forming a protein C-bound acetyl-thioester; oxidized GrdA is then reduced by thioredoxin; glycine/sarcosine/betaine reductase complex protein A 3089314 7120426 EFER_3018 Escherichia fergusonii ATCC 35469 glycine/sarcosine/betaine reductase complex protein A YP_002384117.1 3088985 R 585054 CDS YP_002384118.1 218550327 7120427 complement(3089330..3089458) 1 NC_011740.1 glycine/sarcosine/betaine reductase complex component A 3089458 7120427 EFER_3019 Escherichia fergusonii ATCC 35469 glycine/sarcosine/betaine reductase complex component A YP_002384118.1 3089330 R 585054 CDS YP_002384119.1 218550328 7120428 complement(3089485..3089808) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; thioredoxin (TRX) 3089808 7120428 EFER_3020 Escherichia fergusonii ATCC 35469 thioredoxin (TRX) YP_002384119.1 3089485 R 585054 CDS YP_002384120.1 218550329 7120429 complement(3089805..3091100) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; thioredoxin-disulfide reductase 3091100 7120429 EFER_3021 Escherichia fergusonii ATCC 35469 thioredoxin-disulfide reductase YP_002384120.1 3089805 R 585054 CDS YP_002384121.1 218550330 7123700 complement(3091927..3092706) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; siderophore interacting protein 3092706 yqjH 7123700 yqjH Escherichia fergusonii ATCC 35469 siderophore interacting protein YP_002384121.1 3091927 R 585054 CDS YP_002384122.1 218550331 7119739 3092961..3093587 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator 3093587 yqjI 7119739 yqjI Escherichia fergusonii ATCC 35469 transcriptional regulator YP_002384122.1 3092961 D 585054 CDS YP_002384123.1 218550332 7123588 complement(3093662..3095182) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20015410, 9380671, 9643537, 9190831; Product type r : regulator; bifunctional signal transducer for aerotaxis sensory component/methyl accepting chemotaxis component 3095182 aer 7123588 aer Escherichia fergusonii ATCC 35469 bifunctional signal transducer for aerotaxis sensory component/methyl accepting chemotaxis component YP_002384123.1 3093662 R 585054 CDS YP_002384124.1 218550333 7122279 3095512..3096918 1 NC_011740.1 catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate; putrescine--2-oxoglutarate aminotransferase 3096918 ygjG 7122279 ygjG Escherichia fergusonii ATCC 35469 putrescine--2-oxoglutarate aminotransferase YP_002384124.1 3095512 D 585054 CDS YP_002384125.1 218550334 7123063 3097083..3098267 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3098267 7123063 EFER_3026 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384125.1 3097083 D 585054 CDS YP_002384126.1 218550335 7123701 complement(3098261..3099301) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3099301 7123701 EFER_3027 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384126.1 3098261 R 585054 CDS YP_002384127.1 218550336 7120430 complement(3099562..3100335) 1 NC_011740.1 regulates the expression of uxuBA; DNA-binding transcriptional repressor UxuR 3100335 uxuR 7120430 uxuR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional repressor UxuR YP_002384127.1 3099562 R 585054 CDS YP_002384128.1 218550337 7122653 complement(3100580..3102046) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 73203083, 77222076, 14401695; Product type e : enzyme; D-mannonate oxidoreductase, NAD-binding 3102046 uxuB 7122653 uxuB Escherichia fergusonii ATCC 35469 D-mannonate oxidoreductase, NAD-binding YP_002384128.1 3100580 R 585054 CDS YP_002384129.1 218550338 7123514 complement(3102127..3103311) 1 NC_011740.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 3103311 uxuA 7123514 uxuA Escherichia fergusonii ATCC 35469 mannonate dehydratase YP_002384129.1 3102127 R 585054 CDS YP_002384130.1 218550339 7122652 3103820..3104386 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94293775, 8022277; Product type lp : lipoprotein; outer membrane lipoprotein 3104386 slp 7122652 slp Escherichia fergusonii ATCC 35469 outer membrane lipoprotein YP_002384130.1 3103820 D 585054 CDS YP_002384131.1 218550340 7123924 3104745..3105308 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8022277, 8041620, 9811641, 12399493, 12900028, 12694615; Product type pe : enzyme; HTH-type transcriptional regulator 3105308 dctR 7123924 dctR Escherichia fergusonii ATCC 35469 HTH-type transcriptional regulator YP_002384131.1 3104745 D 585054 CDS YP_002384132.1 218550341 7122876 complement(3105382..3106041) 1 NC_011740.1 inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli; Mg(2+) transport ATPase 3106041 yhiD 7122876 yhiD Escherichia fergusonii ATCC 35469 Mg(2+) transport ATPase YP_002384132.1 3105382 R 585054 CDS YP_002384133.1 218550342 7122514 complement(3106152..3106562) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8455549; acid-resistance protein 3106562 hdeB 7122514 hdeB Escherichia fergusonii ATCC 35469 acid-resistance protein YP_002384133.1 3106152 R 585054 CDS YP_002384134.1 218550343 7120633 complement(3106580..3106963) 1 NC_011740.1 inactive form; acid-resistance protein 3106963 hdeA 7120633 hdeA Escherichia fergusonii ATCC 35469 acid-resistance protein YP_002384134.1 3106580 R 585054 CDS YP_002384135.1 218550344 7123193 3107165..3107734 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8455549; Product type pm : membrane component; acid-resistance membrane protein 3107734 hdeD 7123193 hdeD Escherichia fergusonii ATCC 35469 acid-resistance membrane protein YP_002384135.1 3107165 D 585054 CDS YP_002384136.1 218550345 7120634 3108502..3109029 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8244952, 12399493, 12694615, 12940989, 14702398; Product type f : factor; transcriptional regulator gadE 3109029 gadE 7120634 gadE Escherichia fergusonii ATCC 35469 transcriptional regulator gadE YP_002384136.1 3108502 D 585054 CDS YP_002384137.1 218550346 7123655 3109149..3110438 1 NC_011740.1 with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds; multidrug efflux system protein MdtE 3110438 mdtE 7123655 mdtE Escherichia fergusonii ATCC 35469 multidrug efflux system protein MdtE YP_002384137.1 3109149 D 585054 CDS YP_002384138.1 218550347 7121251 3110464..3113577 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21450803; Product type t : transporter; multidrug transporter, RpoS-dependent 3113577 mdtF 7121251 mdtF Escherichia fergusonii ATCC 35469 multidrug transporter, RpoS-dependent YP_002384138.1 3110464 D 585054 CDS YP_002384139.1 218550348 7121252 complement(3113619..3113783) 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 3113783 7121252 EFER_3040 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384139.1 3113619 R 585054 CDS YP_002384140.1 218550349 7120431 complement(3113803..3114540) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8041620, 9278503, 12446650, 12730179, 14617649; Product type f : factor; AraC-type transcriptional regulator 3114540 gadW 7120431 gadW Escherichia fergusonii ATCC 35469 AraC-type transcriptional regulator YP_002384140.1 3113803 R 585054 CDS YP_002384141.1 218550350 7123115 3115205..3116074 1 NC_011740.1 regulates genes in response to acid and/or during stationary phase; DNA-binding transcriptional regulator GadX 3116074 7123115 EFER_3042 Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator GadX YP_002384141.1 3115205 D 585054 CDS YP_002384142.1 218550351 7120432 3116107..3117393 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8905232, 3038201, 1658595, 8387749, 10696472, 1429631, 10655611; Product type e : enzyme; phosphoanhydride phosphorylase 3117393 7120432 EFER_3043 Escherichia fergusonii ATCC 35469 phosphoanhydride phosphorylase YP_002384142.1 3116107 D 585054 CDS YP_002384143.1 218550352 7120433 3117514..3117807 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3117807 7120433 EFER_3044 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384143.1 3117514 D 585054 CDS YP_002384144.1 218550353 7120434 3118010..3118195 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 3118195 7120434 EFER_3045 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384144.1 3118010 D 585054 CDS YP_002384145.1 218550354 7120435 3118375..3118545 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3118545 7120435 EFER_3046 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384145.1 3118375 D 585054 CDS YP_002384146.1 218550355 7120436 3118932..3119369 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 3119369 7120436 EFER_3047 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384146.1 3118932 D 585054 CDS YP_002384147.1 218550356 7123159 complement(3119515..3120900) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3120900 yhaM 7123159 yhaM Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384147.1 3119515 R 585054 CDS YP_002384148.1 218550357 7119878 complement(3121115..3122446) 1 NC_011740.1 involved in the import of threonine and serine in combination with the import of a proton; threonine/serine transporter TdcC 3122446 tdcC 7119878 tdcC Escherichia fergusonii ATCC 35469 threonine/serine transporter TdcC YP_002384148.1 3121115 R 585054 CDS YP_002384149.1 218550358 7123407 complement(3122468..3123457) 1 NC_011740.1 catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic; threonine dehydratase 3123457 tdcB 7123407 tdcB Escherichia fergusonii ATCC 35469 threonine dehydratase YP_002384149.1 3122468 R 585054 CDS YP_002384150.1 218550359 7123958 3124175..3125326 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3691501, 11106419; Product type pe : enzyme; 2-hydroxyglutaryl-CoA dehydratase 3125326 yjiM 7123958 yjiM Escherichia fergusonii ATCC 35469 2-hydroxyglutaryl-CoA dehydratase YP_002384150.1 3124175 D 585054 CDS YP_002384151.1 218550360 7122030 3125330..3126103 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8365476, 7607244, 15654892; Product type e : enzyme; ATPase, activator of (R)-hydroxyglutaryl-CoA dehydratase 3126103 hgdC 7122030 hgdC Escherichia fergusonii ATCC 35469 ATPase, activator of (R)-hydroxyglutaryl-CoA dehydratase YP_002384151.1 3125330 D 585054 CDS YP_002384152.1 218550361 7123440 3125977..3126354 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3126354 7123440 EFER_3053 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384152.1 3125977 D 585054 CDS YP_002384153.1 218550362 7120437 3126502..3128520 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12840019, 89380266; Product type e : enzyme; 2,4-dienoyl-CoA reductase 3128520 fadH 7120437 fadH Escherichia fergusonii ATCC 35469 2,4-dienoyl-CoA reductase YP_002384153.1 3126502 D 585054 CDS YP_002384154.1 218550363 7123626 complement(3128702..3130513) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20015410, 89034150, 91317710, 10466731, 2033064, 6213619, 6402709, 8384293; Product type r : regulator; methyl-accepting chemotaxis protein I, serine sensor receptor 3130513 tsr 7123626 tsr Escherichia fergusonii ATCC 35469 methyl-accepting chemotaxis protein I, serine sensor receptor YP_002384154.1 3128702 R 585054 CDS YP_002384155.1 218550364 7122175 3130505..3131410 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 14656965; Product type f : factor; transcriptional regulator 3131410 7122175 EFER_3056 Escherichia fergusonii ATCC 35469 transcriptional regulator YP_002384155.1 3130505 D 585054 CDS YP_002384156.1 218550365 7120438 complement(3131420..3132889) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; Na+/proline symporter 3132889 7120438 EFER_3057 Escherichia fergusonii ATCC 35469 Na+/proline symporter YP_002384156.1 3131420 R 585054 CDS YP_002384157.1 218550366 7120439 complement(3132992..3133387) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3133387 7120439 EFER_3058 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384157.1 3132992 R 585054 CDS YP_002384158.1 218550367 7120440 complement(3133391..3134842) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 7763985; Product type e : enzyme; D-aminoacylase 3134842 7120440 EFER_3059 Escherichia fergusonii ATCC 35469 D-aminoacylase YP_002384158.1 3133391 R 585054 CDS YP_002384159.1 218550368 7123160 3135025..3136254 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; aldolase or racemase 3136254 7123160 EFER_3060 Escherichia fergusonii ATCC 35469 aldolase or racemase YP_002384159.1 3135025 D 585054 CDS YP_002384160.1 218550369 7123161 complement(3136344..3136784) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8384293, 8550403; Product type r : regulator; 4-hydroxyphenylacetate degradative operon repressor 3136784 hpaR 7123161 hpaR Escherichia fergusonii ATCC 35469 4-hydroxyphenylacetate degradative operon repressor YP_002384160.1 3136344 R 585054 CDS YP_002384161.1 218550370 7122219 3137055..3138350 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8223600, 8384293, 11863436; Product type e : enzyme; 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase 3138350 hpaG 7122219 hpaG Escherichia fergusonii ATCC 35469 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase YP_002384161.1 3137055 D 585054 CDS YP_002384162.1 218550371 7124002 3138347..3139813 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7737515, 2061311, 8550403; Product type e : enzyme; 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase 3139813 hpaE 7124002 hpaE Escherichia fergusonii ATCC 35469 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase YP_002384162.1 3138347 D 585054 CDS YP_002384163.1 218550372 7122215 3139815..3140666 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8550403; Product type e : enzyme; 3,4-dihydroxyphenylacetate 2,3-dioxygenase 3140666 hpaD 7122215 hpaD Escherichia fergusonii ATCC 35469 3,4-dihydroxyphenylacetate 2,3-dioxygenase YP_002384163.1 3139815 D 585054 CDS YP_002384164.1 218550373 7124001 3140676..3141056 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2194841; Product type e : enzyme; 5-carboxymethyl-2-hydroxymuconate delta-isomerase 3141056 hpaF 7124001 hpaF Escherichia fergusonii ATCC 35469 5-carboxymethyl-2-hydroxymuconate delta-isomerase YP_002384164.1 3140676 D 585054 CDS YP_002384165.1 218550374 7122216 3141106..3141927 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8550403, 9492273; Product type e : enzyme; 2-oxo-hepta-3-ene-1,7-dioic acid hydratase 3141927 hpaH 7122216 hpaH Escherichia fergusonii ATCC 35469 2-oxo-hepta-3-ene-1,7-dioic acid hydratase YP_002384165.1 3141106 D 585054 CDS YP_002384166.1 218550375 7122217 3141797..3142726 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8529896, 8550403; Product type e : enzyme; 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 3142726 hpaI 7122217 hpaI Escherichia fergusonii ATCC 35469 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase YP_002384166.1 3141797 D 585054 CDS YP_002384167.1 218550376 7122218 3142850..3144226 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8550403, 14744977; Product type pt : transporter; 4-hydroxyphenylacetate permease 3144226 7122218 EFER_3068 Escherichia fergusonii ATCC 35469 4-hydroxyphenylacetate permease YP_002384167.1 3142850 D 585054 CDS YP_002384168.1 218550377 7120441 3144236..3145126 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8077235, 8550403; Product type r : regulator; Regulator of the 4HPA-hydroxylase operon 3145126 hpaA 7120441 hpaA Escherichia fergusonii ATCC 35469 Regulator of the 4HPA-hydroxylase operon YP_002384168.1 3144236 D 585054 CDS YP_002384169.1 218550378 7122212 3145377..3146939 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8077235, 8550403, 10653707; Product type e : enzyme; 4-hydroxyphenylacetate 3-monooxygenase large component 3146939 hpaB 7122212 hpaB Escherichia fergusonii ATCC 35469 4-hydroxyphenylacetate 3-monooxygenase large component YP_002384169.1 3145377 D 585054 CDS YP_002384170.1 218550379 7122213 3146957..3147469 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8077235, 8550403, 10633095; Product type e : enzyme; 4-hydroxyphenylacetate 3-monooxygenase small component 3147469 hpaC 7122213 hpaC Escherichia fergusonii ATCC 35469 4-hydroxyphenylacetate 3-monooxygenase small component YP_002384170.1 3146957 D 585054 CDS YP_002384171.1 218550380 7122214 3147548..3147694 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3147694 7122214 EFER_3072 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384171.1 3147548 D 585054 CDS YP_002384172.1 218550381 7120442 3147739..3149889 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3149889 yjiY 7120442 yjiY Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384172.1 3147739 D 585054 CDS YP_002384173.1 218550382 7122034 3149939..3150142 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3150142 yjiX 7122034 yjiX Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384173.1 3149939 D 585054 CDS YP_002384174.1 218550383 7123969 3150153..3151109 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14696199; Product type pe : enzyme; GTP-binding protein YjiA 3151109 yjiA 7123969 yjiA Escherichia fergusonii ATCC 35469 GTP-binding protein YjiA YP_002384174.1 3150153 D 585054 CDS YP_002384175.1 218550384 7122029 complement(3151143..3151586) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3151586 7122029 EFER_3076 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384175.1 3151143 R 585054 CDS YP_002384176.1 218550385 7120443 complement(3151432..3151746) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3151746 7120443 EFER_3077 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384176.1 3151432 R 585054 CDS YP_002384177.1 218550386 7120444 complement(3151875..3152636) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3152636 7120444 EFER_3078 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384177.1 3151875 R 585054 CDS YP_002384178.1 218550387 7123702 3152872..3156384 1 NC_011740.1 restriction endonuclease; the EcoKI enzyme recognizes 5'-AACN(6)GTGC-3'; subunit R is required for both nuclease and ATPase activities; type I restriction enzyme EcoKI subunit R 3156384 hsdR 7123702 hsdR Escherichia fergusonii ATCC 35469 type I restriction enzyme EcoKI subunit R YP_002384178.1 3152872 D 585054 CDS YP_002384179.1 218550388 7122225 3156461..3158050 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88118919, 91216450, 3323532; Product type e : enzyme; DNA methylase M 3158050 hsdM 7122225 hsdM Escherichia fergusonii ATCC 35469 DNA methylase M YP_002384179.1 3156461 D 585054 CDS YP_002384180.1 218550389 7122224 3158047..3159555 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 6304321; Product type e : enzyme; Specificity determinant for hsdM and hsdR 3159555 7122224 EFER_3081 Escherichia fergusonii ATCC 35469 Specificity determinant for hsdM and hsdR YP_002384180.1 3158047 D 585054 CDS YP_002384181.1 218550390 7121186 3159726..3160124 1 NC_011740.1 involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response; endoribonuclease SymE 3160124 yjiW 7121186 yjiW Escherichia fergusonii ATCC 35469 endoribonuclease SymE YP_002384181.1 3159726 D 585054 CDS YP_002384182.1 218550391 7122033 3160286..3161665 1 NC_011740.1 McrB protein together with McrC forms the McrBC restriction system; recognizes N4- and C5-methylcytosine (and 5-hydroxy-methylcytosines); appears to act against 5-methylcytosine preceded by a purine residue; 5-methylcytosine-specific restriction enzyme subunit McrB 3161665 mcrB 7122033 mcrB Escherichia fergusonii ATCC 35469 5-methylcytosine-specific restriction enzyme subunit McrB YP_002384182.1 3160286 D 585054 CDS YP_002384183.1 218550392 7121237 3161665..3162711 1 NC_011740.1 McrC protein together with McrB forms the McrBC restriction system; recognizes N4- and C5-methylcytosine (and 5-hydroxy-methylcytosines); appears to act against 5-methylcytosine preceded by a purine residue; MrcC modulates the specificty of McrB and has DNA cleavage activity; 5-methylcytosine-specific restriction enzyme subunit McrC 3162711 mcrC 7121237 mcrC Escherichia fergusonii ATCC 35469 5-methylcytosine-specific restriction enzyme subunit McrC YP_002384183.1 3161665 D 585054 CDS YP_002384184.1 218550393 7121238 complement(3162768..3169109) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3169109 7121238 EFER_3085 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384184.1 3162768 R 585054 CDS YP_002384185.1 218550394 7120446 complement(3169122..3172460) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3172460 yjgt 7120446 yjgt Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384185.1 3169122 R 585054 CDS YP_002384186.1 218550395 7122026 complement(3172911..3173075) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3173075 yjiS 7122026 yjiS Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384186.1 3172911 R 585054 CDS YP_002384187.1 218550396 7123968 3173252..3174664 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; bifunctional DNA-binding transcriptional regulator/aminotransferase 3174664 yjiR 7123968 yjiR Escherichia fergusonii ATCC 35469 bifunctional DNA-binding transcriptional regulator/aminotransferase YP_002384187.1 3173252 D 585054 CDS YP_002384188.1 218550397 7123967 complement(3174908..3175828) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3175828 7123967 EFER_3089 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384188.1 3174908 R 585054 CDS YP_002384189.1 218550398 7120447 3176307..3177539 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21450803; Product type t : transporter; multidrug efflux system protein 3177539 yjiO 7120447 yjiO Escherichia fergusonii ATCC 35469 multidrug efflux system protein YP_002384189.1 3176307 D 585054 CDS YP_002384190.1 218550399 7122032 3177580..3178860 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3178860 yjiN 7122032 yjiN Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384190.1 3177580 D 585054 CDS YP_002384191.1 218550400 7122031 3179250..3179441 1 NC_011740.1 Evidence 7 : Gene remnant; Product type pe : enzyme; transposase (fragment) 3179441 7122031 EFER_3092 Escherichia fergusonii ATCC 35469 transposase (fragment) YP_002384191.1 3179250 D 585054 CDS YP_002384192.1 218550401 7120448 3179454..3179690 1 NC_011740.1 Evidence 7 : Gene remnant; Product type pe : enzyme; transposase (fragment) 3179690 7120448 EFER_3093 Escherichia fergusonii ATCC 35469 transposase (fragment) YP_002384192.1 3179454 D 585054 CDS YP_002384193.1 218550402 7120449 complement(3180144..3181613) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; protein kinase from phage origin 3181613 7120449 EFER_3094 Escherichia fergusonii ATCC 35469 protein kinase from phage origin YP_002384193.1 3180144 R 585054 CDS YP_002384194.1 218550403 7122546 complement(3181610..3182209) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3182209 7122546 EFER_3095 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384194.1 3181610 R 585054 CDS YP_002384195.1 218550404 7122426 complement(3182160..3183845) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; nucleoside triphosphate hydrolase 3183845 7122426 EFER_3096 Escherichia fergusonii ATCC 35469 nucleoside triphosphate hydrolase YP_002384195.1 3182160 R 585054 CDS YP_002384196.1 218550405 7122427 complement(3183835..3184992) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3184992 7122427 EFER_3097 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384196.1 3183835 R 585054 CDS YP_002384197.1 218550406 7122428 complement(3184995..3185870) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3185870 7122428 EFER_3098 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384197.1 3184995 R 585054 CDS YP_002384198.1 218550407 7122429 complement(3185854..3190140) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3190140 7122429 EFER_3099 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384198.1 3185854 R 585054 CDS YP_002384199.1 218550408 7123478 complement(3190137..3191438) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3191438 7123478 EFER_3100 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384199.1 3190137 R 585054 CDS YP_002384200.1 218550409 7122430 complement(3191441..3193015) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; restriction modification system DNA specificity domain 3193015 7122430 EFER_3101 Escherichia fergusonii ATCC 35469 restriction modification system DNA specificity domain YP_002384200.1 3191441 R 585054 CDS YP_002384201.1 218550410 7122431 complement(3193012..3195159) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; type I restriction-modification system methyltransferase subunit 3195159 7122431 EFER_3102 Escherichia fergusonii ATCC 35469 type I restriction-modification system methyltransferase subunit YP_002384201.1 3193012 R 585054 CDS YP_002384202.1 218550411 7122432 complement(3195210..3195596) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3195596 7122432 EFER_3103 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384202.1 3195210 R 585054 CDS YP_002384203.1 218550412 7122433 complement(3195593..3196936) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; 5-methylcytosine restriction system component 3196936 7122433 EFER_3104 Escherichia fergusonii ATCC 35469 5-methylcytosine restriction system component YP_002384203.1 3195593 R 585054 CDS YP_002384204.1 218550413 7122434 complement(3196929..3199004) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7781618; Product type pe : enzyme; 5-methylcytosine-specific restriction enzyme with GTPase activity 3199004 7122434 EFER_3105 Escherichia fergusonii ATCC 35469 5-methylcytosine-specific restriction enzyme with GTPase activity YP_002384204.1 3196929 R 585054 CDS YP_002384205.1 218550414 7122435 complement(3199174..3200187) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3200187 7122435 EFER_3106 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384205.1 3199174 R 585054 CDS YP_002384206.1 218550415 7122436 3199991..3200266 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3200266 7122436 EFER_3107 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384206.1 3199991 D 585054 CDS YP_002384207.1 218550416 7123215 3201630..3202034 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3202034 7123215 EFER_3110 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384207.1 3201630 D 585054 CDS YP_002384208.1 218550417 7120068 3202109..3203128 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12147722; Product type pe : enzyme; alcohol dehydrogenase 3203128 yjgB 7120068 yjgB Escherichia fergusonii ATCC 35469 alcohol dehydrogenase YP_002384208.1 3202109 D 585054 CDS YP_002384209.1 218550418 7123966 3203134..3203325 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 3203325 7123966 EFER_3112 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384209.1 3203134 D 585054 CDS YP_002384210.1 218550419 7122437 3203258..3204760 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; ATPase 3204760 yjgR 7122437 yjgR Escherichia fergusonii ATCC 35469 ATPase YP_002384210.1 3203258 D 585054 CDS YP_002384211.1 218550420 7122025 complement(3204867..3205907) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; permease 3205907 yraQ 7122025 yraQ Escherichia fergusonii ATCC 35469 permease YP_002384211.1 3204867 R 585054 CDS YP_002384212.1 218550421 7119742 complement(3205980..3206615) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; nucleoside-diphosphate-sugar epimerase 3206615 yraR 7119742 yraR Escherichia fergusonii ATCC 35469 nucleoside-diphosphate-sugar epimerase YP_002384212.1 3205980 R 585054 CDS YP_002384213.1 218550422 7119743 3206743..3207261 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; intracellular protease 3207261 yhbO 7119743 yhbO Escherichia fergusonii ATCC 35469 intracellular protease YP_002384213.1 3206743 D 585054 CDS YP_002384214.1 218550423 7119882 complement(3207241..3207684) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3207684 yhbP 7119882 yhbP Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384214.1 3207241 R 585054 CDS YP_002384215.1 218550424 7123607 3207735..3208037 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; GIY-YIG nuclease superfamily protein 3208037 yhbQ 7123607 yhbQ Escherichia fergusonii ATCC 35469 GIY-YIG nuclease superfamily protein YP_002384215.1 3207735 D 585054 CDS YP_002384216.1 218550425 7119883 complement(3208024..3208527) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; acyltransferase 3208527 yhbS 7119883 yhbS Escherichia fergusonii ATCC 35469 acyltransferase YP_002384216.1 3208024 R 585054 CDS YP_002384217.1 218550426 7119884 complement(3208521..3209045) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; lipid carrier protein 3209045 yhbT 7119884 yhbT Escherichia fergusonii ATCC 35469 lipid carrier protein YP_002384217.1 3208521 R 585054 CDS YP_002384218.1 218550427 7119885 3209254..3210249 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 10206698; Product type e : enzyme; peptidase 3210249 yhbU 7119885 yhbU Escherichia fergusonii ATCC 35469 peptidase YP_002384218.1 3209254 D 585054 CDS YP_002384219.1 218550428 7119886 3210258..3211136 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 10206698; Product type e : enzyme; protease 3211136 yhbV 7119886 yhbV Escherichia fergusonii ATCC 35469 protease YP_002384219.1 3210258 D 585054 CDS YP_002384220.1 218550429 7123067 3211217..3212224 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 3212224 yhbW 7123067 yhbW Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384220.1 3211217 D 585054 CDS YP_002384221.1 218550430 7119887 complement(3212202..3212942) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3212942 7119887 EFER_3124 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384221.1 3212202 R 585054 CDS YP_002384222.1 218550431 7122438 3212874..3213107 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3213107 7122438 EFER_3125 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384222.1 3212874 D 585054 CDS YP_002384223.1 218550432 7122439 3213257..3214144 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9128730; Product type pe : enzyme; triphosphoribosyl-dephospho-CoA transferase 3214144 7122439 EFER_3126 Escherichia fergusonii ATCC 35469 triphosphoribosyl-dephospho-CoA transferase YP_002384223.1 3213257 D 585054 CDS YP_002384224.1 218550433 7122440 3214304..3215512 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9128730; Product type pt : transporter; carboxybiotin decarboxylase subunit of malonate decarboxylase 3215512 7122440 EFER_3127 Escherichia fergusonii ATCC 35469 carboxybiotin decarboxylase subunit of malonate decarboxylase YP_002384224.1 3214304 D 585054 CDS YP_002384225.1 218550434 7124039 3215525..3217192 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 9128730; Product type e : enzyme; Acetyl-S-acyl carrier protein: malonate acyl carrier protein-SH transferase 3217192 7124039 EFER_3128 Escherichia fergusonii ATCC 35469 Acetyl-S-acyl carrier protein: malonate acyl carrier protein-SH transferase YP_002384225.1 3215525 D 585054 CDS YP_002384226.1 218550435 7123479 3217204..3217536 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 9128730; Product type e : enzyme; Malonate decarboxylase acyl carrier protein 3217536 7123479 EFER_3129 Escherichia fergusonii ATCC 35469 Malonate decarboxylase acyl carrier protein YP_002384226.1 3217204 D 585054 CDS YP_002384227.1 218550436 7122441 3217391..3218458 1 NC_011740.1 The beta subunit catalyzes the decarboxylation of the malonyl moiety on coenzyme A; malonate decarboxylase subunit beta 3218458 7122441 EFER_3130 Escherichia fergusonii ATCC 35469 malonate decarboxylase subunit beta YP_002384227.1 3217391 D 585054 CDS YP_002384228.1 218550437 7122442 3218458..3219339 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9128730; Product type pe : enzyme; subunit of malonyl-S-acyl carrier protein: biotin carboxyltransferase 3219339 7122442 EFER_3131 Escherichia fergusonii ATCC 35469 subunit of malonyl-S-acyl carrier protein: biotin carboxyltransferase YP_002384228.1 3218458 D 585054 CDS YP_002384229.1 218550438 7123480 3219355..3220455 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9128730; Product type pc : carrier; acyl carrier protein-SH: acetate 3220455 7123480 EFER_3132 Escherichia fergusonii ATCC 35469 acyl carrier protein-SH: acetate YP_002384229.1 3219355 D 585054 CDS YP_002384230.1 218550439 7123481 3220452..3221138 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9128730; hypothetical protein 3221138 7123481 EFER_3133 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384230.1 3220452 D 585054 CDS YP_002384231.1 218550440 7122443 3221159..3221377 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 9128730; Product type e : enzyme; Biotin protein MadF 3221377 7122443 EFER_3134 Escherichia fergusonii ATCC 35469 Biotin protein MadF YP_002384231.1 3221159 D 585054 CDS YP_002384232.1 218550441 7122444 3221682..3222062 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 9128730; Product type t : transporter; malonate transporter subunit MadL 3222062 7122444 EFER_3135 Escherichia fergusonii ATCC 35469 malonate transporter subunit MadL YP_002384232.1 3221682 D 585054 CDS YP_002384233.1 218550442 7122445 3222079..3222849 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 9128730; Product type t : transporter; malonate transporter subunit MadM 3222849 7122445 EFER_3136 Escherichia fergusonii ATCC 35469 malonate transporter subunit MadM YP_002384233.1 3222079 D 585054 CDS YP_002384234.1 218550443 7122446 3222893..3223324 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3223324 7122446 EFER_3137 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384234.1 3222893 D 585054 CDS YP_002384235.1 218550444 7122447 complement(3223287..3224228) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9208947; Product type f : factor; Malonate utilization transacting regulator MdcR 3224228 7122447 EFER_3138 Escherichia fergusonii ATCC 35469 Malonate utilization transacting regulator MdcR YP_002384235.1 3223287 R 585054 CDS YP_002384236.1 218550445 7122448 complement(3224328..3225572) 1 NC_011740.1 tryptophan transporter of high affinity; tryptophan permease 3225572 mtr 7122448 mtr Escherichia fergusonii ATCC 35469 tryptophan permease YP_002384236.1 3224328 R 585054 CDS YP_002384237.1 218550446 7120641 3225573..3225725 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 3225725 7120641 EFER_3140 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384237.1 3225573 D 585054 CDS YP_002384238.1 218550447 7122449 complement(3225726..3227615) 1 NC_011740.1 participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division; ATP-dependent RNA helicase DeaD 3227615 deaD 7122449 deaD Escherichia fergusonii ATCC 35469 ATP-dependent RNA helicase DeaD YP_002384238.1 3225726 R 585054 CDS YP_002384239.1 218550448 7122881 complement(3227795..3228679) 1 NC_011740.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI 3228679 nlpI 7122881 nlpI Escherichia fergusonii ATCC 35469 lipoprotein NlpI YP_002384239.1 3227795 R 585054 CDS YP_002384240.1 218550449 7123026 complement(3228788..3230992) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87083499, 91198209, 99234021, 99340204, 2432069, 3005122, 6382163, 9008164, 9298646; Product type e : enzyme; polynucleotide phosphorylase/polyadenylase 3230992 pnp 7123026 pnp Escherichia fergusonii ATCC 35469 polynucleotide phosphorylase/polyadenylase YP_002384240.1 3228788 R 585054 CDS YP_002384241.1 218550450 7123951 complement(3231169..3231438) 1 NC_011740.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 3231438 rpsO 7123951 rpsO Escherichia fergusonii ATCC 35469 30S ribosomal protein S15 YP_002384241.1 3231169 R 585054 CDS YP_002384242.1 218550451 7121136 complement(3231587..3232531) 1 NC_011740.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 3232531 truB 7121136 truB Escherichia fergusonii ATCC 35469 tRNA pseudouridine synthase B YP_002384242.1 3231587 R 585054 CDS YP_002384243.1 218550452 7123437 complement(3232531..3232932) 1 NC_011740.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 3232932 rbfA 7123437 rbfA Escherichia fergusonii ATCC 35469 ribosome-binding factor A YP_002384243.1 3232531 R 585054 CDS YP_002384244.1 218550453 7122346 complement(3233095..3235767) 1 NC_011740.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 3235767 infB 7122346 infB Escherichia fergusonii ATCC 35469 translation initiation factor IF-2 YP_002384244.1 3233095 R 585054 CDS YP_002384245.1 218550454 7120738 complement(3235792..3237279) 1 NC_011740.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 3237279 nusA 7120738 nusA Escherichia fergusonii ATCC 35469 transcription elongation factor NusA YP_002384245.1 3235792 R 585054 CDS YP_002384246.1 218550455 7119684 complement(3237307..3237759) 1 NC_011740.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 3237759 yhbC 7119684 yhbC Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384246.1 3237307 R 585054 CDS YP_002384247.1 218550456 7123639 3238390..3239733 1 NC_011740.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 3239733 argG 7123639 argG Escherichia fergusonii ATCC 35469 argininosuccinate synthase YP_002384247.1 3238390 D 585054 CDS YP_002384248.1 218550457 7123714 complement(3239777..3241378) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; inner membrane sulfatase YhbX 3241378 yhbX 7123714 yhbX Escherichia fergusonii ATCC 35469 inner membrane sulfatase YhbX YP_002384248.1 3239777 R 585054 CDS YP_002384249.1 218550458 7123638 complement(3241747..3242079) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20194819, 21125563, 9020118, 94074540, 9564033, 9644254, 9829959, 99298179, 7556084, 8034620, 8045257, 8244950, 8253068; Product type t : transporter; preprotein translocase subunit SecG 3242079 secG 7123638 secG Escherichia fergusonii ATCC 35469 preprotein translocase subunit SecG YP_002384249.1 3241747 R 585054 CDS YP_002384250.1 218550459 7123373 complement(3242307..3243644) 1 NC_011740.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 3243644 glmM 7123373 glmM Escherichia fergusonii ATCC 35469 phosphoglucosamine mutase YP_002384250.1 3242307 R 585054 CDS YP_002384251.1 218550460 7120191 complement(3243637..3244485) 1 NC_011740.1 catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate; dihydropteroate synthase 3244485 folP 7120191 folP Escherichia fergusonii ATCC 35469 dihydropteroate synthase YP_002384251.1 3243637 R 585054 CDS YP_002384252.1 218550461 7123006 complement(3244575..3246509) 1 NC_011740.1 inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; ATP-dependent metalloprotease 3246509 hflB 7123006 hflB Escherichia fergusonii ATCC 35469 ATP-dependent metalloprotease YP_002384252.1 3244575 R 585054 CDS YP_002384253.1 218550462 7120148 complement(3246609..3247238) 1 NC_011740.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase J 3247238 rrmJ 7120148 rrmJ Escherichia fergusonii ATCC 35469 23S rRNA methyltransferase J YP_002384253.1 3246609 R 585054 CDS YP_002384254.1 218550463 7121143 3247364..3247657 1 NC_011740.1 RNA binding protein found associated to pre-50S subunit of the ribosome; role in ribosome assembly; necessary for optimal growth but not cell viability; RNA-binding protein YhbY 3247657 yhbY 7121143 yhbY Escherichia fergusonii ATCC 35469 RNA-binding protein YhbY YP_002384254.1 3247364 D 585054 CDS YP_002384255.1 218550464 7119889 complement(3247813..3248289) 1 NC_011740.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 3248289 greA 7119889 greA Escherichia fergusonii ATCC 35469 transcription elongation factor GreA YP_002384255.1 3247813 R 585054 CDS YP_002384256.1 218550465 7123188 3248537..3249970 1 NC_011740.1 penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 3249970 dacB 7123188 dacB Escherichia fergusonii ATCC 35469 D-alanyl-D-alanine carboxypeptidase YP_002384256.1 3248537 D 585054 CDS YP_002384257.1 218550466 7122861 complement(3250011..3251183) 1 NC_011740.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 3251183 obgE 7122861 obgE Escherichia fergusonii ATCC 35469 GTPase ObgE YP_002384257.1 3250011 R 585054 CDS YP_002384258.1 218550467 7119689 complement(3251199..3252164) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3252164 yhbE 7119689 yhbE Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384258.1 3251199 R 585054 CDS YP_002384259.1 218550468 7119880 complement(3252291..3252548) 1 NC_011740.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 3252548 rpmA 7119880 rpmA Escherichia fergusonii ATCC 35469 50S ribosomal protein L27 YP_002384259.1 3252291 R 585054 CDS YP_002384260.1 218550469 7121112 complement(3252569..3252880) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91088242, 94146411, 10094780, 387076, 8312607; Product type s : structure; 50S ribosomal protein L21 3252880 rplU 7121112 rplU Escherichia fergusonii ATCC 35469 50S ribosomal protein L21 YP_002384260.1 3252569 R 585054 CDS YP_002384261.1 218550470 7121108 3253140..3254111 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94311902, 97284515, 2670911, 8037730, 8312607; Product type e : enzyme; octaprenyl diphosphate synthase 3254111 ispB 7121108 ispB Escherichia fergusonii ATCC 35469 octaprenyl diphosphate synthase YP_002384261.1 3253140 D 585054 CDS YP_002384262.1 218550471 7120791 3254312..3254635 1 NC_011740.1 activator of maltose metabolism genes; DNA-binding transcriptional regulator Nlp 3254635 sfsB 7120791 sfsB Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator Nlp YP_002384262.1 3254312 D 585054 CDS YP_002384263.1 218550472 7121776 complement(3254689..3255948) 1 NC_011740.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 3255948 murA 7121776 murA Escherichia fergusonii ATCC 35469 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_002384263.1 3254689 R 585054 CDS YP_002384264.1 218550473 7123194 complement(3256002..3256256) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator 3256256 yrbA 7123194 yrbA Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YP_002384264.1 3256002 R 585054 CDS YP_002384265.1 218550474 7119744 complement(3256382..3256675) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3256675 yrbB 7119744 yrbB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384265.1 3256382 R 585054 CDS YP_002384266.1 218550475 7119745 complement(3256675..3257310) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 9658016; Product type t : transporter; toluene ABC transporter membrane protein 3257310 yrbC 7119745 yrbC Escherichia fergusonii ATCC 35469 toluene ABC transporter membrane protein YP_002384266.1 3256675 R 585054 CDS YP_002384267.1 218550476 7119746 complement(3257329..3257895) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 9658016; Product type t : transporter; toluene ABC transporter membrane protein 3257895 yrbD 7119746 yrbD Escherichia fergusonii ATCC 35469 toluene ABC transporter membrane protein YP_002384267.1 3257329 R 585054 CDS YP_002384268.1 218550477 7119747 complement(3257885..3258667) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 9658016; Product type t : transporter; toluene ABC transporter membrane protein 3258667 yrbE 7119747 yrbE Escherichia fergusonii ATCC 35469 toluene ABC transporter membrane protein YP_002384268.1 3257885 R 585054 CDS YP_002384269.1 218550478 7119748 complement(3258675..3259490) 1 NC_011740.1 ATP-binding subunit of a ABC toluene efflux transporter; ABC transporter ATP-binding protein 3259490 yrbF 7119748 yrbF Escherichia fergusonii ATCC 35469 ABC transporter ATP-binding protein YP_002384269.1 3258675 R 585054 CDS YP_002384270.1 218550479 7119749 3259666..3260679 1 NC_011740.1 YrbG; inner membrane protein involved in cell envelope integrity; sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers; calcium/sodium:proton antiporter 3260679 yrbG 7119749 yrbG Escherichia fergusonii ATCC 35469 calcium/sodium:proton antiporter YP_002384270.1 3259666 D 585054 CDS YP_002384271.1 218550480 7123042 3260693..3261679 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12805358; Product type e : enzyme; D-arabinose 5-phosphate isomerase 3261679 kdsD 7123042 kdsD Escherichia fergusonii ATCC 35469 D-arabinose 5-phosphate isomerase YP_002384271.1 3260693 D 585054 CDS YP_002384272.1 218550481 7123225 3261697..3262263 1 NC_011740.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 3262263 kdsC 7123225 kdsC Escherichia fergusonii ATCC 35469 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase YP_002384272.1 3261697 D 585054 CDS YP_002384273.1 218550482 7123224 3262260..3262835 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3262835 yrbK 7123224 yrbK Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384273.1 3262260 D 585054 CDS YP_002384274.1 218550483 7123043 3262804..3263361 1 NC_011740.1 LptA; periplasmic binding protein part of a ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system; lipopolysaccharide transport periplasmic protein LptA 3263361 lptA 7123043 lptA Escherichia fergusonii ATCC 35469 lipopolysaccharide transport periplasmic protein LptA YP_002384274.1 3262804 D 585054 CDS YP_002384275.1 218550484 7121196 3263368..3264093 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7876255, 9298646, 17056748; Product type pt : transporter; ABC transporter ATP-binding protein 3264093 lptB 7121196 lptB Escherichia fergusonii ATCC 35469 ABC transporter ATP-binding protein YP_002384275.1 3263368 D 585054 CDS YP_002384276.1 218550485 7121198 3264141..3265574 1 NC_011740.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 3265574 rpoN 7121198 rpoN Escherichia fergusonii ATCC 35469 RNA polymerase factor sigma-54 YP_002384276.1 3264141 D 585054 CDS YP_002384277.1 218550486 7121124 3265597..3265884 1 NC_011740.1 YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing; sigma(54) modulation protein 3265884 yhbH 7121124 yhbH Escherichia fergusonii ATCC 35469 sigma(54) modulation protein YP_002384277.1 3265597 D 585054 CDS YP_002384278.1 218550487 7123606 3266004..3266495 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88212176, 90136533, 90274974, 95020584, 95181483, 7876255, 8025669, 8444818, 9636714; Product type t : transporter; PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN 3266495 ptsN 7123606 ptsN Escherichia fergusonii ATCC 35469 PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN YP_002384278.1 3266004 D 585054 CDS YP_002384279.1 218550488 7122316 3266541..3267395 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3267395 yhbJ 7122316 yhbJ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384279.1 3266541 D 585054 CDS YP_002384280.1 218550489 7119881 3267392..3267664 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10473571, 95181483, 7876255, 8025669; Product type t : transporter; PTS system phosphohistidinoprotein-hexose phosphotransferase Npr 3267664 npr 7119881 npr Escherichia fergusonii ATCC 35469 PTS system phosphohistidinoprotein-hexose phosphotransferase Npr YP_002384280.1 3267392 D 585054 CDS YP_002384281.1 218550490 7119657 3267861..3268493 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 89083480; hypothetical protein 3268493 yrbL 7119657 yrbL Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384281.1 3267861 D 585054 CDS YP_002384282.1 218550491 7119750 complement(3268490..3269215) 1 NC_011740.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase 3269215 mtgA 7119750 mtgA Escherichia fergusonii ATCC 35469 monofunctional biosynthetic peptidoglycan transglycosylase YP_002384282.1 3268490 R 585054 CDS YP_002384283.1 218550492 7120389 complement(3269212..3269865) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92246944, 98269038, 1575737, 9603997; Product type pe : enzyme; isoprenoid biosynthesis protein 3269865 elbB 7120389 elbB Escherichia fergusonii ATCC 35469 isoprenoid biosynthesis protein YP_002384283.1 3269212 R 585054 CDS YP_002384284.1 218550493 7121183 complement(3270094..3272430) 1 NC_011740.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; aerobic respiration control sensor protein ArcB 3272430 arcB 7121183 arcB Escherichia fergusonii ATCC 35469 aerobic respiration control sensor protein ArcB YP_002384284.1 3270094 R 585054 CDS YP_002384285.1 218550494 7120533 complement(3272525..3273454) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; Fe-S oxidoreductase 3273454 yhcC 7120533 yhcC Escherichia fergusonii ATCC 35469 Fe-S oxidoreductase YP_002384285.1 3272525 R 585054 CDS YP_002384286.1 218550495 7123068 3274027..3278580 1 NC_011740.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; glutamate synthase subunit alpha 3278580 gltB 7123068 gltB Escherichia fergusonii ATCC 35469 glutamate synthase subunit alpha YP_002384286.1 3274027 D 585054 CDS YP_002384287.1 218550496 7120583 3278593..3280011 1 NC_011740.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 3280011 gltD 7120583 gltD Escherichia fergusonii ATCC 35469 glutamate synthase subunit beta YP_002384287.1 3278593 D 585054 CDS YP_002384288.1 218550497 7123185 3280195..3281322 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3281322 yhcG 7123185 yhcG Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384288.1 3280195 D 585054 CDS YP_002384289.1 218550498 7119891 complement(3281382..3281846) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3281846 yhcH 7119891 yhcH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384289.1 3281382 R 585054 CDS YP_002384290.1 218550499 7119892 complement(3281843..3282718) 1 NC_011740.1 catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase 3282718 nanK 7119892 nanK Escherichia fergusonii ATCC 35469 N-acetylmannosamine kinase YP_002384290.1 3281843 R 585054 CDS YP_002384291.1 218550500 7120667 complement(3282715..3283404) 1 NC_011740.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 3283404 nanE 7120667 nanE Escherichia fergusonii ATCC 35469 N-acetylmannosamine-6-phosphate 2-epimerase YP_002384291.1 3282715 R 585054 CDS YP_002384292.1 218550501 7120666 complement(3283451..3284941) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96011396, 9864311, 7592358; Product type t : transporter; sialic acid transporter 3284941 nanT 7120666 nanT Escherichia fergusonii ATCC 35469 sialic acid transporter YP_002384292.1 3283451 R 585054 CDS YP_002384293.1 218550502 7120669 complement(3285050..3285943) 1 NC_011740.1 catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase 3285943 nanA 7120669 nanA Escherichia fergusonii ATCC 35469 N-acetylneuraminate lyase YP_002384293.1 3285050 R 585054 CDS YP_002384294.1 218550503 7120665 complement(3286065..3286847) 1 NC_011740.1 Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization; transcriptional regulator NanR 3286847 nanR 7120665 nanR Escherichia fergusonii ATCC 35469 transcriptional regulator NanR YP_002384294.1 3286065 R 585054 CDS YP_002384295.1 218550504 7120668 complement(3286965..3287468) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12445774, 94293773, 1721886, 3029697, 8022275; Product type f : factor; ClpXP protease specificity-enhancing factor 3287468 sspB 7120668 sspB Escherichia fergusonii ATCC 35469 ClpXP protease specificity-enhancing factor YP_002384295.1 3286965 R 585054 CDS YP_002384296.1 218550505 7123401 complement(3287474..3288112) 1 NC_011740.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; stringent starvation protein A 3288112 sspA 7123401 sspA Escherichia fergusonii ATCC 35469 stringent starvation protein A YP_002384296.1 3287474 R 585054 CDS YP_002384297.1 218550506 7123400 3288194..3288370 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3288370 7123400 EFER_3200 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384297.1 3288194 D 585054 CDS YP_002384298.1 218550507 7124040 complement(3288428..3288820) 1 NC_011740.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 3288820 rpsI 7124040 rpsI Escherichia fergusonii ATCC 35469 30S ribosomal protein S9 YP_002384298.1 3288428 R 585054 CDS YP_002384299.1 218550508 7123271 complement(3288836..3289264) 1 NC_011740.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 3289264 rplM 7123271 rplM Escherichia fergusonii ATCC 35469 50S ribosomal protein L13 YP_002384299.1 3288836 R 585054 CDS YP_002384300.1 218550509 7121103 complement(3289483..3290610) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3290610 yhcM 7121103 yhcM Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384300.1 3289483 R 585054 CDS YP_002384301.1 218550510 7119893 3290804..3291202 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16079137; Product type pe : enzyme; cytochrome d ubiquinol oxidase subunit III 3291202 yhcB 7119893 yhcB Escherichia fergusonii ATCC 35469 cytochrome d ubiquinol oxidase subunit III YP_002384301.1 3290804 D 585054 CDS YP_002384302.1 218550511 7119890 3291357..3292724 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8830688, 96165272, 8576051, 8576052, 9740056; Product type e : enzyme; serine endoprotease 3292724 degQ 7119890 degQ Escherichia fergusonii ATCC 35469 serine endoprotease YP_002384302.1 3291357 D 585054 CDS YP_002384303.1 218550512 7123549 3292814..3293881 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15137941, 15225661, 21352996, 96165272, 99431977, 3322223, 8576051; Product type e : enzyme; serine endoprotease 3293881 degS 7123549 degS Escherichia fergusonii ATCC 35469 serine endoprotease YP_002384303.1 3292814 D 585054 CDS YP_002384304.1 218550513 7122885 complement(3293909..3294085) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; oxaloacetate decarboxylase beta chain 1 (fragment) 3294085 7122885 EFER_3207 Escherichia fergusonii ATCC 35469 oxaloacetate decarboxylase beta chain 1 (fragment) YP_002384304.1 3293909 R 585054 CDS YP_002384305.1 218550514 7122450 complement(3294331..3294948) 1 NC_011740.1 Involved in the tartrate degradation pathway; L(+)-tartrate dehydratase subunit beta 3294948 7122450 EFER_3208 Escherichia fergusonii ATCC 35469 L(+)-tartrate dehydratase subunit beta YP_002384305.1 3294331 R 585054 CDS YP_002384306.1 218550515 7122451 complement(3294948..3295847) 1 NC_011740.1 Involved in the tartrate degradation pathway; tartrate dehydratase subunit alpha 3295847 ttdA 7122451 ttdA Escherichia fergusonii ATCC 35469 tartrate dehydratase subunit alpha YP_002384306.1 3294948 R 585054 CDS YP_002384307.1 218550516 7122177 complement(3295879..3297189) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; charged metabolite transporter 3297189 7122177 EFER_3210 Escherichia fergusonii ATCC 35469 charged metabolite transporter YP_002384307.1 3295879 R 585054 CDS YP_002384308.1 218550517 7122452 complement(3297359..3298024) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; regulatory protein, gntR family 3298024 7122452 EFER_3211 Escherichia fergusonii ATCC 35469 regulatory protein, gntR family YP_002384308.1 3297359 R 585054 CDS YP_002384309.1 218550518 7122453 complement(3298011..3298802) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; GntR family transcriptional regulator 3298802 7122453 EFER_3212 Escherichia fergusonii ATCC 35469 GntR family transcriptional regulator YP_002384309.1 3298011 R 585054 CDS YP_002384310.1 218550519 7124041 complement(3298780..3299718) 1 NC_011740.1 oxidizes malate to oxaloacetate; malate dehydrogenase 3299718 mdh 7124041 mdh Escherichia fergusonii ATCC 35469 malate dehydrogenase YP_002384310.1 3298780 R 585054 CDS YP_002384311.1 218550520 7121240 complement(3299825..3299995) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3299995 7121240 EFER_3214 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384311.1 3299825 R 585054 CDS YP_002384312.1 218550521 7124042 3300133..3300603 1 NC_011740.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor 3300603 argR 7124042 argR Escherichia fergusonii ATCC 35469 arginine repressor YP_002384312.1 3300133 D 585054 CDS YP_002384313.1 218550522 7120543 3300957..3301220 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3301220 yhcN 7120543 yhcN Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384313.1 3300957 D 585054 CDS YP_002384314.1 218550523 7119894 complement(3301278..3301661) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; barnase inhibitor 3301661 7119894 EFER_3217 Escherichia fergusonii ATCC 35469 barnase inhibitor YP_002384314.1 3301278 R 585054 CDS YP_002384315.1 218550524 7122454 complement(3301664..3303631) 1 NC_011740.1 with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeB 3303631 aaeB 7122454 aaeB Escherichia fergusonii ATCC 35469 p-hydroxybenzoic acid efflux subunit AaeB YP_002384315.1 3301664 R 585054 CDS YP_002384316.1 218550525 7122245 complement(3303637..3304569) 1 NC_011740.1 with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeA 3304569 aaeA 7122245 aaeA Escherichia fergusonii ATCC 35469 p-hydroxybenzoic acid efflux subunit AaeA YP_002384316.1 3303637 R 585054 CDS YP_002384317.1 218550526 7122244 complement(3304577..3304780) 1 NC_011740.1 membrane protein AaeX; the gene is a member of the aaeXAB operon; hypothetical protein 3304780 aaeX 7122244 aaeX Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384317.1 3304577 R 585054 CDS YP_002384318.1 218550527 7122246 3304964..3305893 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15489430; Product type r : regulator; DNA-binding transcriptional regulator 3305893 aaeR 7122246 aaeR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YP_002384318.1 3304964 D 585054 CDS YP_002384319.1 218550528 7123450 complement(3305973..3307418) 1 NC_011740.1 responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; protease TldD 3307418 tldD 7123450 tldD Escherichia fergusonii ATCC 35469 protease TldD YP_002384319.1 3305973 R 585054 CDS YP_002384320.1 218550529 7123986 complement(3307573..3311364) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10960106; Product type pm : membrane component; hypothetical protein 3311364 yhdP 7123986 yhdP Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384320.1 3307573 R 585054 CDS YP_002384321.1 218550530 7123609 complement(3311420..3312889) 1 NC_011740.1 involved in the processing of the 5'end of 16S rRNA; ribonuclease G 3312889 rng 7123609 rng Escherichia fergusonii ATCC 35469 ribonuclease G YP_002384321.1 3311420 R 585054 CDS YP_002384322.1 218550531 7121426 complement(3312879..3313472) 1 NC_011740.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 3313472 yhdE 7121426 yhdE Escherichia fergusonii ATCC 35469 Maf-like protein YP_002384322.1 3312879 R 585054 CDS YP_002384323.1 218550532 7123069 complement(3313490..3313978) 1 NC_011740.1 part of cell wall structural complex MreBCD; transmembrane component; rod shape-determining protein MreD 3313978 mreD 7123069 mreD Escherichia fergusonii ATCC 35469 rod shape-determining protein MreD YP_002384323.1 3313490 R 585054 CDS YP_002384324.1 218550533 7120968 complement(3313978..3315042) 1 NC_011740.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 3315042 mreC 7120968 mreC Escherichia fergusonii ATCC 35469 rod shape-determining protein MreC YP_002384324.1 3313978 R 585054 CDS YP_002384325.1 218550534 7120967 complement(3315108..3316151) 1 NC_011740.1 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 3316151 mreB 7120967 mreB Escherichia fergusonii ATCC 35469 rod shape-determining protein MreB YP_002384325.1 3315108 R 585054 CDS YP_002384326.1 218550535 7120966 complement(3316458..3318398) 1 NC_011740.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules; regulatory protein CsrD 3318398 csrD 7120966 csrD Escherichia fergusonii ATCC 35469 regulatory protein CsrD YP_002384326.1 3316458 R 585054 CDS YP_002384327.1 218550536 7122825 3318550..3319524 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; oxidoreductase 3319524 yhdH 7122825 yhdH Escherichia fergusonii ATCC 35469 oxidoreductase YP_002384327.1 3318550 D 585054 CDS YP_002384328.1 218550537 7119895 3319622..3320626 1 NC_011740.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; sulfite oxidase subunit YedY 3320626 yedY 7119895 yedY Escherichia fergusonii ATCC 35469 sulfite oxidase subunit YedY YP_002384328.1 3319622 D 585054 CDS YP_002384329.1 218550538 7121543 3320627..3321226 1 NC_011740.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; sulfite oxidase subunit YedZ 3321226 yedZ 7121543 yedZ Escherichia fergusonii ATCC 35469 sulfite oxidase subunit YedZ YP_002384329.1 3320627 D 585054 CDS YP_002384330.1 218550539 7121544 3321614..3322084 1 NC_011740.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 3322084 accB 7121544 accB Escherichia fergusonii ATCC 35469 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit YP_002384330.1 3321614 D 585054 CDS YP_002384331.1 218550540 7122254 3322095..3323444 1 NC_011740.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 3323444 accC 7122254 accC Escherichia fergusonii ATCC 35469 acetyl-CoA carboxylase biotin carboxylase subunit YP_002384331.1 3322095 D 585054 CDS YP_002384332.1 218550541 7122255 3323553..3323795 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3323795 yhdT 7122255 yhdT Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384332.1 3323553 D 585054 CDS YP_002384333.1 218550542 7119898 3323785..3325236 1 NC_011740.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 3325236 panF 7119898 panF Escherichia fergusonii ATCC 35469 sodium/panthothenate symporter YP_002384333.1 3323785 D 585054 CDS YP_002384334.1 218550543 7122555 3325248..3326129 1 NC_011740.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 3326129 prmA 7122555 prmA Escherichia fergusonii ATCC 35469 50S ribosomal protein L11 methyltransferase YP_002384334.1 3325248 D 585054 CDS YP_002384335.1 218550544 7120130 3326458..3327423 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 22095566, 1459953, 1547773, 2835774, 2837762, 8226664; Product type e : enzyme; tRNA-dihydrouridine synthase B 3327423 dusB 7120130 dusB Escherichia fergusonii ATCC 35469 tRNA-dihydrouridine synthase B YP_002384335.1 3326458 D 585054 CDS YP_002384336.1 218550545 7122928 3327449..3327745 1 NC_011740.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis 3327745 fis 7122928 fis Escherichia fergusonii ATCC 35469 DNA-binding protein Fis YP_002384336.1 3327449 D 585054 CDS YP_002384337.1 218550546 7120019 3327810..3328709 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15028690, 9073062; Product type e : enzyme; methyltransferase 3328709 yhdJ 7120019 yhdJ Escherichia fergusonii ATCC 35469 methyltransferase YP_002384337.1 3327810 D 585054 CDS YP_002384338.1 218550547 7123608 3328797..3328961 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3328961 7123608 EFER_3242 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384338.1 3328797 D 585054 CDS YP_002384339.1 218550548 7122455 complement(3328979..3329638) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator EnvR 3329638 7122455 EFER_3243 Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator EnvR YP_002384339.1 3328979 R 585054 CDS YP_002384340.1 218550549 7122456 3330045..3331202 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94012493, 1720861; Product type lp : lipoprotein; hypothetical protein 3331202 acrE 7122456 acrE Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384340.1 3330045 D 585054 CDS YP_002384341.1 218550550 7122268 3331214..3334327 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94262163, 99449638, 1720861, 8407802; Product type t : transporter; multidrug efflux system protein 3334327 acrF 7122268 acrF Escherichia fergusonii ATCC 35469 multidrug efflux system protein YP_002384341.1 3331214 D 585054 CDS YP_002384342.1 218550551 7122269 3334558..3334779 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3334779 yhdV 7122269 yhdV Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384342.1 3334558 D 585054 CDS YP_002384343.1 218550552 7123746 3335230..3336147 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 8898392; Product type t : transporter; amino-acid ABC transporter periplasmic-binding protein 3336147 aapJ 7123746 aapJ Escherichia fergusonii ATCC 35469 amino-acid ABC transporter periplasmic-binding protein YP_002384343.1 3335230 D 585054 CDS YP_002384344.1 218550553 7122247 3336215..3337396 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 8898392; Product type t : transporter; amino-acid ABC transporter membrane protein 3337396 aapQ 7122247 aapQ Escherichia fergusonii ATCC 35469 amino-acid ABC transporter membrane protein YP_002384344.1 3336215 D 585054 CDS YP_002384345.1 218550554 7122250 3337406..3338509 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 8898392; Product type t : transporter; amino-acid ABC transporter membrane protein 3338509 aapM 7122250 aapM Escherichia fergusonii ATCC 35469 amino-acid ABC transporter membrane protein YP_002384345.1 3337406 D 585054 CDS YP_002384346.1 218550555 7122248 3338517..3339275 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 8809753, 8898392; Product type t : transporter; amino-acid ABC transporter ATP-binding protein 3339275 aapP 7122248 aapP Escherichia fergusonii ATCC 35469 amino-acid ABC transporter ATP-binding protein YP_002384346.1 3338517 D 585054 CDS YP_002384347.1 218550556 7120386 3345001..3345882 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3345882 yrdA 7120386 yrdA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384347.1 3345001 D 585054 CDS YP_002384348.1 218550557 7123044 complement(3346112..3346930) 1 NC_011740.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 3346930 aroE 7123044 aroE Escherichia fergusonii ATCC 35469 shikimate 5-dehydrogenase YP_002384348.1 3346112 R 585054 CDS YP_002384349.1 218550558 7120547 complement(3346935..3347507) 1 NC_011740.1 RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA; ribosome maturation factor 3347507 yrdC 7120547 yrdC Escherichia fergusonii ATCC 35469 ribosome maturation factor YP_002384349.1 3346935 R 585054 CDS YP_002384350.1 218550559 7119751 complement(3347512..3348054) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; DNA topoisomerase 3348054 yrdD 7119751 yrdD Escherichia fergusonii ATCC 35469 DNA topoisomerase YP_002384350.1 3347512 R 585054 CDS YP_002384351.1 218550560 7119752 complement(3348083..3348556) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8432722; hypothetical protein 3348556 smg 7119752 smg Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384351.1 3348083 R 585054 CDS YP_002384352.1 218550561 7121794 complement(3348528..3349652) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8112305, 8432722; DNA protecting protein DprA 3349652 smf 7121794 smf Escherichia fergusonii ATCC 35469 DNA protecting protein DprA YP_002384352.1 3348528 R 585054 CDS YP_002384353.1 218550562 7121793 3349782..3350291 1 NC_011740.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 3350291 def 7121793 def Escherichia fergusonii ATCC 35469 peptide deformylase YP_002384353.1 3349782 D 585054 CDS YP_002384354.1 218550563 7122884 3350306..3351253 1 NC_011740.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 3351253 fmt 7122884 fmt Escherichia fergusonii ATCC 35469 methionyl-tRNA formyltransferase YP_002384354.1 3350306 D 585054 CDS YP_002384355.1 218550564 7122999 3351299..3352588 1 NC_011740.1 catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase; 16S rRNA methyltransferase B 3352588 rsmB 7122999 rsmB Escherichia fergusonii ATCC 35469 16S rRNA methyltransferase B YP_002384355.1 3351299 D 585054 CDS YP_002384356.1 218550565 7121149 3352610..3353986 1 NC_011740.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein 3353986 trkA 7121149 trkA Escherichia fergusonii ATCC 35469 potassium transporter peripheral membrane protein YP_002384356.1 3352610 D 585054 CDS YP_002384357.1 218550566 7122157 3354116..3354526 1 NC_011740.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 3354526 mscL 7122157 mscL Escherichia fergusonii ATCC 35469 large-conductance mechanosensitive channel YP_002384357.1 3354116 D 585054 CDS YP_002384358.1 218550567 7120972 complement(3354523..3354741) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3354741 yhdL 7120972 yhdL Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384358.1 3354523 R 585054 CDS YP_002384359.1 218550568 7119896 complement(3354797..3355222) 1 NC_011740.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators; zinc-responsive transcriptional regulator 3355222 zntR 7119896 zntR Escherichia fergusonii ATCC 35469 zinc-responsive transcriptional regulator YP_002384359.1 3354797 R 585054 CDS YP_002384360.1 218550569 7119774 complement(3355233..3355601) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3355601 yhdN 7119774 yhdN Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384360.1 3355233 R 585054 CDS YP_002384361.1 218550570 7119897 complement(3355708..3356091) 1 NC_011740.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 3356091 rplQ 7119897 rplQ Escherichia fergusonii ATCC 35469 50S ribosomal protein L17 YP_002384361.1 3355708 R 585054 CDS YP_002384362.1 218550571 7123809 complement(3356132..3357121) 1 NC_011740.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 3357121 rpoA 7123809 rpoA Escherichia fergusonii ATCC 35469 DNA-directed RNA polymerase subunit alpha YP_002384362.1 3356132 R 585054 CDS YP_002384363.1 218550572 7121119 complement(3357147..3357767) 1 NC_011740.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 3357767 rpsD 7121119 rpsD Escherichia fergusonii ATCC 35469 30S ribosomal protein S4 YP_002384363.1 3357147 R 585054 CDS YP_002384364.1 218550573 7121129 complement(3357801..3358190) 1 NC_011740.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 3358190 rpsK 7121129 rpsK Escherichia fergusonii ATCC 35469 30S ribosomal protein S11 YP_002384364.1 3357801 R 585054 CDS YP_002384365.1 218550574 7121134 complement(3358207..3358563) 1 NC_011740.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 3358563 rpsM 7121134 rpsM Escherichia fergusonii ATCC 35469 30S ribosomal protein S13 YP_002384365.1 3358207 R 585054 CDS YP_002384366.1 218550575 7123273 complement(3358858..3360189) 1 NC_011740.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 3360189 secY 7123273 secY Escherichia fergusonii ATCC 35469 preprotein translocase subunit SecY YP_002384366.1 3358858 R 585054 CDS YP_002384367.1 218550576 7121765 complement(3360197..3360631) 1 NC_011740.1 late assembly protein; 50S ribosomal protein L15 3360631 rplO 7121765 rplO Escherichia fergusonii ATCC 35469 50S ribosomal protein L15 YP_002384367.1 3360197 R 585054 CDS YP_002384368.1 218550577 7121104 complement(3360635..3360814) 1 NC_011740.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 3360814 rpmD 7121104 rpmD Escherichia fergusonii ATCC 35469 50S ribosomal protein L30 YP_002384368.1 3360635 R 585054 CDS YP_002384369.1 218550578 7121115 complement(3360818..3361321) 1 NC_011740.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 3361321 rpsE 7121115 rpsE Escherichia fergusonii ATCC 35469 30S ribosomal protein S5 YP_002384369.1 3360818 R 585054 CDS YP_002384370.1 218550579 7121130 complement(3361336..3361689) 1 NC_011740.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 3361689 rplR 7121130 rplR Escherichia fergusonii ATCC 35469 50S ribosomal protein L18 YP_002384370.1 3361336 R 585054 CDS YP_002384371.1 218550580 7121105 complement(3361699..3362232) 1 NC_011740.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 3362232 rplF 7121105 rplF Escherichia fergusonii ATCC 35469 50S ribosomal protein L6 YP_002384371.1 3361699 R 585054 CDS YP_002384372.1 218550581 7123370 complement(3362245..3362637) 1 NC_011740.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 3362637 rpsH 7123370 rpsH Escherichia fergusonii ATCC 35469 30S ribosomal protein S8 YP_002384372.1 3362245 R 585054 CDS YP_002384373.1 218550582 7123270 complement(3362671..3362976) 1 NC_011740.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 3362976 rpsN 7123270 rpsN Escherichia fergusonii ATCC 35469 30S ribosomal protein S14 YP_002384373.1 3362671 R 585054 CDS YP_002384374.1 218550583 7121135 complement(3362991..3363530) 1 NC_011740.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 3363530 rplE 7121135 rplE Escherichia fergusonii ATCC 35469 50S ribosomal protein L5 YP_002384374.1 3362991 R 585054 CDS YP_002384375.1 218550584 7121441 complement(3363545..3363859) 1 NC_011740.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 3363859 rplX 7121441 rplX Escherichia fergusonii ATCC 35469 50S ribosomal protein L24 YP_002384375.1 3363545 R 585054 CDS YP_002384376.1 218550585 7121110 complement(3363870..3364241) 1 NC_011740.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 3364241 rplN 7121110 rplN Escherichia fergusonii ATCC 35469 50S ribosomal protein L14 YP_002384376.1 3363870 R 585054 CDS YP_002384377.1 218550586 7123267 complement(3364406..3364660) 1 NC_011740.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 3364660 rpsQ 7123267 rpsQ Escherichia fergusonii ATCC 35469 30S ribosomal protein S17 YP_002384377.1 3364406 R 585054 CDS YP_002384378.1 218550587 7121138 complement(3364660..3364851) 1 NC_011740.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 3364851 rpmC 7121138 rpmC Escherichia fergusonii ATCC 35469 50S ribosomal protein L29 YP_002384378.1 3364660 R 585054 CDS YP_002384379.1 218550588 7121114 complement(3364851..3365261) 1 NC_011740.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 3365261 rplP 7121114 rplP Escherichia fergusonii ATCC 35469 50S ribosomal protein L16 YP_002384379.1 3364851 R 585054 CDS YP_002384380.1 218550589 7123808 complement(3365274..3365975) 1 NC_011740.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 3365975 rpsC 7123808 rpsC Escherichia fergusonii ATCC 35469 30S ribosomal protein S3 YP_002384380.1 3365274 R 585054 CDS YP_002384381.1 218550590 7121128 complement(3365993..3366325) 1 NC_011740.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 3366325 rplV 7121128 rplV Escherichia fergusonii ATCC 35469 50S ribosomal protein L22 YP_002384381.1 3365993 R 585054 CDS YP_002384382.1 218550591 7121109 complement(3366340..3366618) 1 NC_011740.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 3366618 rpsS 7121109 rpsS Escherichia fergusonii ATCC 35469 30S ribosomal protein S19 YP_002384382.1 3366340 R 585054 CDS YP_002384383.1 218550592 7121139 complement(3366635..3367456) 1 NC_011740.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 3367456 rplB 7121139 rplB Escherichia fergusonii ATCC 35469 50S ribosomal protein L2 YP_002384383.1 3366635 R 585054 CDS YP_002384384.1 218550593 7121439 complement(3367474..3367776) 1 NC_011740.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 3367776 rplW 7121439 rplW Escherichia fergusonii ATCC 35469 50S ribosomal protein L23 YP_002384384.1 3367474 R 585054 CDS YP_002384385.1 218550594 7123810 complement(3367773..3368378) 1 NC_011740.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 3368378 rplD 7123810 rplD Escherichia fergusonii ATCC 35469 50S ribosomal protein L4 YP_002384385.1 3367773 R 585054 CDS YP_002384386.1 218550595 7121440 complement(3368389..3369018) 1 NC_011740.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 3369018 rplC 7121440 rplC Escherichia fergusonii ATCC 35469 50S ribosomal protein L3 YP_002384386.1 3368389 R 585054 CDS YP_002384387.1 218550596 7123320 complement(3369051..3369362) 1 NC_011740.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 3369362 rpsJ 7123320 rpsJ Escherichia fergusonii ATCC 35469 30S ribosomal protein S10 YP_002384387.1 3369051 R 585054 CDS YP_002384388.1 218550597 7121133 3369741..3370214 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; bifunctional prepilin peptidase HopD: leader peptidase; methyl transferase 3370214 7121133 EFER_3306 Escherichia fergusonii ATCC 35469 bifunctional prepilin peptidase HopD: leader peptidase; methyl transferase YP_002384388.1 3369741 D 585054 CDS YP_002384389.1 218550598 7122457 complement(3370204..3370680) 1 NC_011740.1 iron storage protein; bacterioferritin 3370680 bfr 7122457 bfr Escherichia fergusonii ATCC 35469 bacterioferritin YP_002384389.1 3370204 R 585054 CDS YP_002384390.1 218550599 7123358 complement(3370753..3370947) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8954950, 9889981, 2661540, 8639572; Product type c : carrier; bacterioferritin-associated ferredoxin 3370947 bfd 7123358 bfd Escherichia fergusonii ATCC 35469 bacterioferritin-associated ferredoxin YP_002384390.1 3370753 R 585054 CDS YP_002384391.1 218550600 7121659 complement(3371130..3372314) 1 NC_011740.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 3372314 tufA 7121659 tufA Escherichia fergusonii ATCC 35469 elongation factor Tu YP_002384391.1 3371130 R 585054 CDS YP_002384392.1 218550601 7123993 complement(3372385..3374499) 1 NC_011740.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 3374499 fusA 7123993 fusA Escherichia fergusonii ATCC 35469 elongation factor G YP_002384392.1 3372385 R 585054 CDS YP_002384393.1 218550602 7123114 complement(3374596..3375066) 1 NC_011740.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 3375066 rpsG 7123114 rpsG Escherichia fergusonii ATCC 35469 30S ribosomal protein S7 YP_002384393.1 3374596 R 585054 CDS YP_002384394.1 218550603 7121132 complement(3375163..3375537) 1 NC_011740.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 3375537 rpsL 7121132 rpsL Escherichia fergusonii ATCC 35469 30S ribosomal protein S12 YP_002384394.1 3375163 R 585054 CDS YP_002384395.1 218550604 7123272 complement(3375663..3375950) 1 NC_011740.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusB 3375950 tusB 7123272 tusB Escherichia fergusonii ATCC 35469 sulfur transfer complex subunit TusB YP_002384395.1 3375663 R 585054 CDS YP_002384396.1 218550605 7122607 complement(3375958..3376317) 1 NC_011740.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC 3376317 tusC 7122607 tusC Escherichia fergusonii ATCC 35469 sulfur relay protein TusC YP_002384396.1 3375958 R 585054 CDS YP_002384397.1 218550606 7122608 complement(3376317..3376703) 1 NC_011740.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD 3376703 tusD 7122608 tusD Escherichia fergusonii ATCC 35469 sulfur transfer complex subunit TusD YP_002384397.1 3376317 R 585054 CDS YP_002384398.1 218550607 7122609 complement(3376703..3377425) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator 3377425 yheO 7122609 yheO Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YP_002384398.1 3376703 R 585054 CDS YP_002384399.1 218550608 7122486 complement(3377592..3378404) 1 NC_011740.1 rotamase; FKBP-type peptidyl-prolyl cis-trans isomerase 3378404 fkpA 7122486 fkpA Escherichia fergusonii ATCC 35469 FKBP-type peptidyl-prolyl cis-trans isomerase YP_002384399.1 3377592 R 585054 CDS YP_002384400.1 218550609 7120024 3378624..3378842 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3378842 slyX 7120024 slyX Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384400.1 3378624 D 585054 CDS YP_002384401.1 218550610 7123925 complement(3378891..3379481) 1 NC_011740.1 rotamase; FKBP-type peptidyl-prolyl cis-trans isomerase 3379481 slyD 7123925 slyD Escherichia fergusonii ATCC 35469 FKBP-type peptidyl-prolyl cis-trans isomerase YP_002384401.1 3378891 R 585054 CDS YP_002384402.1 218550611 7121792 complement(3379576..3379776) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3379776 yheV 7121792 yheV Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384402.1 3379576 R 585054 CDS YP_002384403.1 218550612 7122490 complement(3379786..3381591) 1 NC_011740.1 involved in potassium efflux; glutathione-regulated potassium-efflux system protein KefB 3381591 kefB 7122490 kefB Escherichia fergusonii ATCC 35469 glutathione-regulated potassium-efflux system protein KefB YP_002384403.1 3379786 R 585054 CDS YP_002384404.1 218550613 7120812 complement(3381591..3382145) 1 NC_011740.1 required for KefB activity; glutathione-regulated potassium-efflux system ancillary protein KefG 3382145 kefG 7120812 kefG Escherichia fergusonii ATCC 35469 glutathione-regulated potassium-efflux system ancillary protein KefG YP_002384404.1 3381591 R 585054 CDS YP_002384405.1 218550614 7123226 3382273..3384186 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter ATP-binding protein 3384186 yheS 7123226 yheS Escherichia fergusonii ATCC 35469 ABC transporter ATP-binding protein YP_002384405.1 3382273 D 585054 CDS YP_002384406.1 218550615 7122487 3384186..3385208 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9889164; Product type pe : enzyme; hydrolase 3385208 yheT 7122487 yheT Escherichia fergusonii ATCC 35469 hydrolase YP_002384406.1 3384186 D 585054 CDS YP_002384407.1 218550616 7122488 3385202..3385420 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3385420 yheU 7122488 yheU Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384407.1 3385202 D 585054 CDS YP_002384408.1 218550617 7122489 complement(3385461..3385535) 1 NC_011740.1 hypothetical protein 3385535 7122489 EFER_3327 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384408.1 3385461 R 585054 CDS YP_002384409.1 218550618 7123482 3385474..3386343 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 2559876; Product type e : enzyme; phosphoribulokinase 3386343 prkB 7123482 prkB Escherichia fergusonii ATCC 35469 phosphoribulokinase YP_002384409.1 3385474 D 585054 CDS YP_002384410.1 218550619 7120128 complement(3386398..3386802) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3386802 yhfA 7120128 yhfA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384410.1 3386398 R 585054 CDS YP_002384411.1 218550620 7123537 3387107..3387739 1 NC_011740.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 3387739 crp 7123537 crp Escherichia fergusonii ATCC 35469 cAMP-regulatory protein YP_002384411.1 3387107 D 585054 CDS YP_002384412.1 218550621 7122808 3387778..3389880 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3389880 yhfK 7122808 yhfK Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384412.1 3387778 D 585054 CDS YP_002384413.1 218550622 7122491 complement(3389958..3391178) 1 NC_011740.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase 3391178 argD 7122491 argD Escherichia fergusonii ATCC 35469 bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase YP_002384413.1 3389958 R 585054 CDS YP_002384414.1 218550623 7123177 complement(3391264..3391827) 1 NC_011740.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II 3391827 pabA 7123177 pabA Escherichia fergusonii ATCC 35469 para-aminobenzoate synthase component II YP_002384414.1 3391264 R 585054 CDS YP_002384415.1 218550624 7124060 complement(3391859..3392461) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92021789, 94095125, 2007139, 2403545, 2546924, 7549107; Product type cp : cell process; cell filamentation protein Fic 3392461 fic 7124060 fic Escherichia fergusonii ATCC 35469 cell filamentation protein Fic YP_002384415.1 3391859 R 585054 CDS YP_002384416.1 218550625 7120017 complement(3392451..3392618) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3392618 yhfG 7120017 yhfG Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384416.1 3392451 R 585054 CDS YP_002384417.1 218550626 7124048 complement(3392723..3393295) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90272647, 91175755, 1606970, 2001362, 2007139, 2190212, 2403545, 2546924, 8130188, 8180197; Product type e : enzyme; peptidyl-prolyl cis-trans isomerase A 3393295 ppiA 7124048 ppiA Escherichia fergusonii ATCC 35469 peptidyl-prolyl cis-trans isomerase A YP_002384417.1 3392723 R 585054 CDS YP_002384418.1 218550627 7120113 3393684..3396227 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93062014, 2200672, 2445993, 2543955; Product type e : enzyme; nitrite reductase, large subunit 3396227 nirB 7120113 nirB Escherichia fergusonii ATCC 35469 nitrite reductase, large subunit YP_002384418.1 3393684 D 585054 CDS YP_002384419.1 218550628 7123205 3396224..3396550 1 NC_011740.1 involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations; nitrite reductase small subunit 3396550 nirD 7123205 nirD Escherichia fergusonii ATCC 35469 nitrite reductase small subunit YP_002384419.1 3396224 D 585054 CDS YP_002384420.1 218550629 7120696 3396677..3397483 1 NC_011740.1 member of the FNT family of formate and nitrite transporters; nitrite transporter NirC 3397483 nirC 7120696 nirC Escherichia fergusonii ATCC 35469 nitrite transporter NirC YP_002384420.1 3396677 D 585054 CDS YP_002384421.1 218550630 7120695 3397502..3398875 1 NC_011740.1 multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin; siroheme synthase 3398875 cysG 7120695 cysG Escherichia fergusonii ATCC 35469 siroheme synthase YP_002384421.1 3397502 D 585054 CDS YP_002384422.1 218550631 7122850 3399125..3399292 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3399292 yhfL 7122850 yhfL Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384422.1 3399125 D 585054 CDS YP_002384423.1 218550632 7122492 complement(3399399..3400484) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3400484 yhfS 7122492 yhfS Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384423.1 3399399 R 585054 CDS YP_002384424.1 218550633 7124049 complement(3400496..3401800) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3401800 yhfT 7124049 yhfT Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384424.1 3400496 R 585054 CDS YP_002384425.1 218550634 7122493 complement(3401812..3402165) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3402165 yhfU 7122493 yhfU Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384425.1 3401812 R 585054 CDS YP_002384426.1 218550635 7122494 complement(3402176..3403054) 1 NC_011740.1 phosphotriesterase homology protein; PhP; YhfV; member of a family of proteins related to phosphotriesterase (PTE); hydrolase 3403054 php 7122494 php Escherichia fergusonii ATCC 35469 hydrolase YP_002384426.1 3402176 R 585054 CDS YP_002384427.1 218550636 7122605 complement(3403051..3404277) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; mutase 3404277 yhfW 7122605 yhfW Escherichia fergusonii ATCC 35469 mutase YP_002384427.1 3403051 R 585054 CDS YP_002384428.1 218550637 7122495 complement(3404277..3405440) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; amino acid racemase 3405440 yhfX 7122495 yhfX Escherichia fergusonii ATCC 35469 amino acid racemase YP_002384428.1 3404277 R 585054 CDS YP_002384429.1 218550638 7122496 complement(3405524..3405886) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3405886 yhfY 7122496 yhfY Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384429.1 3405524 R 585054 CDS YP_002384430.1 218550639 7122497 complement(3405903..3406808) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3406808 yhfZ 7122497 yhfZ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384430.1 3405903 R 585054 CDS YP_002384431.1 218550640 7122498 complement(3406969..3407973) 1 NC_011740.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 3407973 trpS 7122498 trpS Escherichia fergusonii ATCC 35469 tryptophanyl-tRNA synthetase YP_002384431.1 3406969 R 585054 CDS YP_002384432.1 218550641 7122168 complement(3407966..3408724) 1 NC_011740.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase 3408724 gph 7122168 gph Escherichia fergusonii ATCC 35469 phosphoglycolate phosphatase YP_002384432.1 3407966 R 585054 CDS YP_002384433.1 218550642 7120608 complement(3408717..3409394) 1 NC_011740.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 3409394 rpe 7120608 rpe Escherichia fergusonii ATCC 35469 ribulose-phosphate 3-epimerase YP_002384433.1 3408717 R 585054 CDS YP_002384434.1 218550643 7121434 complement(3409412..3410248) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90136529, 92262475, 92272672, 2549371, 6300769, 7603433, 8341592; Product type e : enzyme; DNA adenine methylase 3410248 dam 7121434 dam Escherichia fergusonii ATCC 35469 DNA adenine methylase YP_002384434.1 3409412 R 585054 CDS YP_002384435.1 218550644 7122864 complement(3410365..3411645) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3411645 damX 7122864 damX Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384435.1 3410365 R 585054 CDS YP_002384436.1 218550645 7122865 complement(3411737..3412825) 1 NC_011740.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 3412825 aroB 7122865 aroB Escherichia fergusonii ATCC 35469 3-dehydroquinate synthase YP_002384436.1 3411737 R 585054 CDS YP_002384437.1 218550646 7120545 complement(3412883..3413404) 1 NC_011740.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I 3413404 aroK 7120545 aroK Escherichia fergusonii ATCC 35469 shikimate kinase I YP_002384437.1 3412883 R 585054 CDS YP_002384438.1 218550647 7120551 complement(3413872..3415152) 1 NC_011740.1 outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa; outer membrane porin HofQ 3415152 hofQ 7120551 hofQ Escherichia fergusonii ATCC 35469 outer membrane porin HofQ YP_002384438.1 3413872 R 585054 CDS YP_002384439.1 218550648 7122207 complement(3415022..3415426) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3415426 7122207 EFER_3358 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384439.1 3415022 R 585054 CDS YP_002384440.1 218550649 7123483 complement(3415416..3416024) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3416024 7123483 EFER_3359 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384440.1 3415416 R 585054 CDS YP_002384441.1 218550650 7122458 complement(3415858..3416397) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3416397 7122458 EFER_3360 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384441.1 3415858 R 585054 CDS YP_002384442.1 218550651 7122459 complement(3416397..3417221) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; pilus assembly protein 3417221 yrfD 7122459 yrfD Escherichia fergusonii ATCC 35469 pilus assembly protein YP_002384442.1 3416397 R 585054 CDS YP_002384443.1 218550652 7119753 3417297..3419849 1 NC_011740.1 bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits; peptidoglycan synthetase 3419849 mrcA 7119753 mrcA Escherichia fergusonii ATCC 35469 peptidoglycan synthetase YP_002384443.1 3417297 D 585054 CDS YP_002384444.1 218550653 7123248 complement(3419982..3420542) 1 NC_011740.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE 3420542 nudE 7123248 nudE Escherichia fergusonii ATCC 35469 ADP-ribose diphosphatase NudE YP_002384444.1 3419982 R 585054 CDS YP_002384445.1 218550654 7123029 3420865..3423000 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11553591; Product type r : regulator; intracellular growth attenuator protein 3423000 igaA 7123029 igaA Escherichia fergusonii ATCC 35469 intracellular growth attenuator protein YP_002384445.1 3420865 D 585054 CDS YP_002384446.1 218550655 7123742 3423065..3423733 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hydrolase 3423733 yrfG 7123742 yrfG Escherichia fergusonii ATCC 35469 hydrolase YP_002384446.1 3423065 D 585054 CDS YP_002384447.1 218550656 7119754 3423744..3424145 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9867837, 10675343, 10675344; Product type f : factor; ribosome-associated heat shock protein Hsp15 3424145 hslR 7119754 hslR Escherichia fergusonii ATCC 35469 ribosome-associated heat shock protein Hsp15 YP_002384447.1 3423744 D 585054 CDS YP_002384448.1 218550657 7122228 3424170..3425048 1 NC_011740.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 3425048 hslO 7122228 hslO Escherichia fergusonii ATCC 35469 Hsp33-like chaperonin YP_002384448.1 3424170 D 585054 CDS YP_002384449.1 218550658 7122227 complement(3425088..3426821) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3426821 yhgE 7122227 yhgE Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384449.1 3425088 R 585054 CDS YP_002384450.1 218550659 7123487 3427186..3428808 1 NC_011740.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 3428808 pck 7123487 pck Escherichia fergusonii ATCC 35469 phosphoenolpyruvate carboxykinase YP_002384450.1 3427186 D 585054 CDS YP_002384451.1 218550660 7122564 3428924..3429241 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3429241 7122564 EFER_3370 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384451.1 3428924 D 585054 CDS YP_002384452.1 218550661 7122460 3429299..3429595 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2404279; Product type pr : regulator; HTH-type transcriptional regulator yiaG 3429595 7122460 EFER_3371 Escherichia fergusonii ATCC 35469 HTH-type transcriptional regulator yiaG YP_002384452.1 3429299 D 585054 CDS YP_002384453.1 218550662 7122461 complement(3429627..3430979) 1 NC_011740.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; osmolarity sensor protein 3430979 envZ 7122461 envZ Escherichia fergusonii ATCC 35469 osmolarity sensor protein YP_002384453.1 3429627 R 585054 CDS YP_002384454.1 218550663 7122954 complement(3430976..3431695) 1 NC_011740.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; osmolarity response regulator 3431695 ompR 7122954 ompR Escherichia fergusonii ATCC 35469 osmolarity response regulator YP_002384454.1 3430976 R 585054 CDS YP_002384455.1 218550664 7123578 3431923..3432399 1 NC_011740.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 3432399 greB 7123578 greB Escherichia fergusonii ATCC 35469 transcription elongation factor GreB YP_002384455.1 3431923 D 585054 CDS YP_002384456.1 218550665 7120614 3432496..3434817 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 8755871; Product type f : factor; transcriptional accessory protein 3434817 yhgF 7120614 yhgF Escherichia fergusonii ATCC 35469 transcriptional accessory protein YP_002384456.1 3432496 D 585054 CDS YP_002384457.1 218550666 7123488 3435254..3435481 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94012482, 8407793; Product type t : transporter; ferrous iron transport protein A 3435481 feoA 7123488 feoA Escherichia fergusonii ATCC 35469 ferrous iron transport protein A YP_002384457.1 3435254 D 585054 CDS YP_002384458.1 218550667 7120003 3435498..3437819 1 NC_011740.1 cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake; ferrous iron transport protein B 3437819 feoB 7120003 feoB Escherichia fergusonii ATCC 35469 ferrous iron transport protein B YP_002384458.1 3435498 D 585054 CDS YP_002384459.1 218550668 7120004 3437819..3438055 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator 3438055 yhgG 7120004 yhgG Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YP_002384459.1 3437819 D 585054 CDS YP_002384460.1 218550669 7122500 3438257..3439150 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2678009; Product type ph : phenotype; hypothetical protein 3439150 yhgA 7122500 yhgA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384460.1 3438257 D 585054 CDS YP_002384461.1 218550670 7122499 complement(3439370..3440140) 1 NC_011740.1 Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis; carboxylesterase BioH 3440140 bioH 7122499 bioH Escherichia fergusonii ATCC 35469 carboxylesterase BioH YP_002384461.1 3439370 R 585054 CDS YP_002384462.1 218550671 7121670 3440178..3440861 1 NC_011740.1 involved in high-affinity gluconate transport; gluconate periplasmic binding protein 3440861 gntX 7121670 gntX Escherichia fergusonii ATCC 35469 gluconate periplasmic binding protein YP_002384462.1 3440178 D 585054 CDS YP_002384463.1 218550672 7120600 3440921..3441496 1 NC_011740.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; DNA uptake protein 3441496 gntY 7120600 gntY Escherichia fergusonii ATCC 35469 DNA uptake protein YP_002384463.1 3440921 D 585054 CDS YP_002384464.1 218550673 7120601 3441813..3443129 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 172599, 4574689, 4582156, 93139975, 97141270, 98019089, 2845225, 3040894, 7984428, 9045817; Product type t : transporter; gluconate transporter, high-affinity GNT I system 3443129 gntT 7120601 gntT Escherichia fergusonii ATCC 35469 gluconate transporter, high-affinity GNT I system YP_002384464.1 3441813 D 585054 CDS YP_002384465.1 218550674 7120598 complement(3443174..3445258) 1 NC_011740.1 amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 3445258 malQ 7120598 malQ Escherichia fergusonii ATCC 35469 4-alpha-glucanotransferase YP_002384465.1 3443174 R 585054 CDS YP_002384466.1 218550675 7123830 complement(3445268..3447661) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89033892, 10220320, 10469642, 2845225, 3037809, 3155826, 6283313, 6339728, 6986282, 9009262; Product type e : enzyme; maltodextrin phosphorylase 3447661 malP 7123830 malP Escherichia fergusonii ATCC 35469 maltodextrin phosphorylase YP_002384466.1 3445268 R 585054 CDS YP_002384467.1 218550676 7123288 3448272..3450977 1 NC_011740.1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides; transcriptional regulator MalT 3450977 malT 7123288 malT Escherichia fergusonii ATCC 35469 transcriptional regulator MalT YP_002384467.1 3448272 D 585054 CDS YP_002384468.1 218550677 7121227 complement(3451020..3452036) 1 NC_011740.1 catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester; RNA 3'-terminal-phosphate cyclase 3452036 rtcA 7121227 rtcA Escherichia fergusonii ATCC 35469 RNA 3'-terminal-phosphate cyclase YP_002384468.1 3451020 R 585054 CDS YP_002384469.1 218550678 7121160 complement(3452040..3453266) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9738023; hypothetical protein 3453266 rtcB 7121160 rtcB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384469.1 3452040 R 585054 CDS YP_002384470.1 218550679 7121161 3453455..3455053 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9738023, 3045764, 7920643, 7984428; Product type r : regulator; sigma 54-dependent transcriptional regulator of rtcBA expression 3455053 rtcR 7121161 rtcR Escherichia fergusonii ATCC 35469 sigma 54-dependent transcriptional regulator of rtcBA expression YP_002384470.1 3453455 D 585054 CDS YP_002384471.1 218550680 7123276 complement(3455035..3455793) 1 NC_011740.1 represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; DNA-binding transcriptional repressor GlpR 3455793 glpR 7123276 glpR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional repressor GlpR YP_002384471.1 3455035 R 585054 CDS YP_002384472.1 218550681 7123184 complement(3455810..3456640) 1 NC_011740.1 protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity; intramembrane serine protease GlpG 3456640 glpG 7123184 glpG Escherichia fergusonii ATCC 35469 intramembrane serine protease GlpG YP_002384472.1 3455810 R 585054 CDS YP_002384473.1 218550682 7120578 complement(3456685..3457011) 1 NC_011740.1 belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine; thiosulfate sulfurtransferase 3457011 glpE 7120578 glpE Escherichia fergusonii ATCC 35469 thiosulfate sulfurtransferase YP_002384473.1 3456685 R 585054 CDS YP_002384474.1 218550683 7120576 3457201..3458706 1 NC_011740.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 3458706 glpD 7120576 glpD Escherichia fergusonii ATCC 35469 glycerol-3-phosphate dehydrogenase YP_002384474.1 3457201 D 585054 CDS YP_002384475.1 218550684 7120452 complement(3458738..3459190) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3459190 7120452 EFER_3395 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384475.1 3458738 R 585054 CDS YP_002384476.1 218550685 7123484 complement(3459203..3460255) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; ankyrin repeat-containing protein 3460255 7123484 EFER_3396 Escherichia fergusonii ATCC 35469 ankyrin repeat-containing protein YP_002384476.1 3459203 R 585054 CDS YP_002384477.1 218550686 7122462 complement(3460335..3461900) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter component 3461900 7122462 EFER_3397 Escherichia fergusonii ATCC 35469 transporter component YP_002384477.1 3460335 R 585054 CDS YP_002384478.1 218550687 7122463 complement(3462034..3463185) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; fimbrial adhesin 3463185 7122463 EFER_3398 Escherichia fergusonii ATCC 35469 fimbrial adhesin YP_002384478.1 3462034 R 585054 CDS YP_002384479.1 218550688 7122464 complement(3463178..3463978) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; periplasmic pilin chaperone 3463978 7122464 EFER_3399 Escherichia fergusonii ATCC 35469 periplasmic pilin chaperone YP_002384479.1 3463178 R 585054 CDS YP_002384480.1 218550689 7122465 complement(3463920..3464444) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; fimbrial-like adhesin protein 3464444 7122465 EFER_3400 Escherichia fergusonii ATCC 35469 fimbrial-like adhesin protein YP_002384480.1 3463920 R 585054 CDS YP_002384481.1 218550690 7122466 complement(3464452..3465024) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; fimbrial minor structural subunit 3465024 7122466 EFER_3401 Escherichia fergusonii ATCC 35469 fimbrial minor structural subunit YP_002384481.1 3464452 R 585054 CDS YP_002384482.1 218550691 7122467 complement(3465015..3467606) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15213132; Product type pf : factor; outer membrane export usher protein aufC 3467606 7122467 EFER_3402 Escherichia fergusonii ATCC 35469 outer membrane export usher protein aufC YP_002384482.1 3465015 R 585054 CDS YP_002384483.1 218550692 7124043 complement(3467647..3468399) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; fimbria chaperone protein 3468399 7124043 EFER_3403 Escherichia fergusonii ATCC 35469 fimbria chaperone protein YP_002384483.1 3467647 R 585054 CDS YP_002384484.1 218550693 7122468 complement(3468519..3469223) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15213132; Product type s : structure; Auf fimbriae major fimbrial subunit AufA 3469223 aufA 7122468 aufA Escherichia fergusonii ATCC 35469 Auf fimbriae major fimbrial subunit AufA YP_002384484.1 3468519 R 585054 CDS YP_002384485.1 218550694 7121640 complement(3469713..3472160) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88330897, 91104907, 91236706, 2645169, 2975249, 3047129, 3097003; Product type e : enzyme; glycogen phosphorylase 3472160 glgP 7121640 glgP Escherichia fergusonii ATCC 35469 glycogen phosphorylase YP_002384485.1 3469713 R 585054 CDS YP_002384486.1 218550695 7120187 complement(3472180..3473613) 1 NC_011740.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 3473613 glgA 7120187 glgA Escherichia fergusonii ATCC 35469 glycogen synthase YP_002384486.1 3472180 R 585054 CDS YP_002384487.1 218550696 7120185 complement(3473613..3474908) 1 NC_011740.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 3474908 glgC 7120185 glgC Escherichia fergusonii ATCC 35469 glucose-1-phosphate adenylyltransferase YP_002384487.1 3473613 R 585054 CDS YP_002384488.1 218550697 7123118 complement(3474924..3476900) 1 NC_011740.1 catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen; glycogen debranching protein 3476900 glgX 7123118 glgX Escherichia fergusonii ATCC 35469 glycogen debranching protein YP_002384488.1 3474924 R 585054 CDS YP_002384489.1 218550698 7120189 complement(3476897..3479083) 1 NC_011740.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein 3479083 glgB 7120189 glgB Escherichia fergusonii ATCC 35469 glycogen branching protein YP_002384489.1 3476897 R 585054 CDS YP_002384490.1 218550699 7120186 complement(3479354..3480565) 1 NC_011740.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 3480565 asd 7120186 asd Escherichia fergusonii ATCC 35469 aspartate-semialdehyde dehydrogenase YP_002384490.1 3479354 R 585054 CDS YP_002384491.1 218550700 7120563 3480650..3481243 1 NC_011740.1 YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP); dITP- and XTP- hydrolase 3481243 yhgN 7120563 yhgN Escherichia fergusonii ATCC 35469 dITP- and XTP- hydrolase YP_002384491.1 3480650 D 585054 CDS YP_002384492.1 218550701 7122501 complement(3481300..3482640) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8655507, 9119199, 9135111, 97141270; Product type t : transporter; low affinity gluconate transporter 3482640 gntU 7122501 gntU Escherichia fergusonii ATCC 35469 low affinity gluconate transporter YP_002384492.1 3481300 R 585054 CDS YP_002384493.1 218550702 7120599 complement(3482644..3483171) 1 NC_011740.1 thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate; gluconate kinase 3483171 gntK 7120599 gntK Escherichia fergusonii ATCC 35469 gluconate kinase YP_002384493.1 3482644 R 585054 CDS YP_002384494.1 218550703 7120596 complement(3483310..3484305) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 172599, 9135111, 93139975, 9537375, 8655507; Product type r : regulator; DNA-binding transcriptional repressor 3484305 gntR 7120596 gntR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional repressor YP_002384494.1 3483310 R 585054 CDS YP_002384495.1 218550704 7120597 complement(3484398..3485093) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3485093 yhhW 7120597 yhhW Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384495.1 3484398 R 585054 CDS YP_002384496.1 218550705 7122511 complement(3485216..3486253) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10493123; Product type pe : enzyme; dehydrogenase 3486253 yhhX 7122511 yhhX Escherichia fergusonii ATCC 35469 dehydrogenase YP_002384496.1 3485216 R 585054 CDS YP_002384497.1 218550706 7123823 3486587..3487075 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; acetyltransferase 3487075 yhhY 7123823 yhhY Escherichia fergusonii ATCC 35469 acetyltransferase YP_002384497.1 3486587 D 585054 CDS YP_002384498.1 218550707 7122513 3487185..3487469 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3487469 yrhB 7122513 yrhB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384498.1 3487185 D 585054 CDS YP_002384499.1 218550708 7119755 complement(3487507..3489318) 1 NC_011740.1 periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides; gamma-glutamyltranspeptidase 3489318 ggt 7119755 ggt Escherichia fergusonii ATCC 35469 gamma-glutamyltranspeptidase YP_002384499.1 3487507 R 585054 CDS YP_002384500.1 218550709 7120183 3489373..3489813 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3489813 yhhA 7120183 yhhA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384500.1 3489373 D 585054 CDS YP_002384501.1 218550710 7122502 complement(3489800..3490543) 1 NC_011740.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate; glycerophosphodiester phosphodiesterase 3490543 ugpQ 7122502 ugpQ Escherichia fergusonii ATCC 35469 glycerophosphodiester phosphodiesterase YP_002384501.1 3489800 R 585054 CDS YP_002384502.1 218550711 7122628 complement(3490540..3491610) 1 NC_011740.1 part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit 3491610 ugpC 7122628 ugpC Escherichia fergusonii ATCC 35469 glycerol-3-phosphate transporter ATP-binding subunit YP_002384502.1 3490540 R 585054 CDS YP_002384503.1 218550712 7122627 complement(3491612..3492457) 1 NC_011740.1 with UgpABC is involved in uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter membrane protein 3492457 ugpE 7122627 ugpE Escherichia fergusonii ATCC 35469 glycerol-3-phosphate transporter membrane protein YP_002384503.1 3491612 R 585054 CDS YP_002384504.1 218550713 7123508 complement(3492454..3493341) 1 NC_011740.1 with UgpEC is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter permease 3493341 ugpA 7123508 ugpA Escherichia fergusonii ATCC 35469 glycerol-3-phosphate transporter permease YP_002384504.1 3492454 R 585054 CDS YP_002384505.1 218550714 7122625 complement(3493439..3494755) 1 NC_011740.1 with UgpACE is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter periplasmic binding protein 3494755 ugpB 7122625 ugpB Escherichia fergusonii ATCC 35469 glycerol-3-phosphate transporter periplasmic binding protein YP_002384505.1 3493439 R 585054 CDS YP_002384506.1 218550715 7122626 complement(3494988..3495734) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3495734 7122626 EFER_3426 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384506.1 3494988 R 585054 CDS YP_002384507.1 218550716 7122469 complement(3495853..3496566) 1 NC_011740.1 with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit 3496566 livF 7122469 livF Escherichia fergusonii ATCC 35469 leucine/isoleucine/valine transporter ATP-binding subunit YP_002384507.1 3495853 R 585054 CDS YP_002384508.1 218550717 7120836 complement(3496568..3497335) 1 NC_011740.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit 3497335 livG 7120836 livG Escherichia fergusonii ATCC 35469 leucine/isoleucine/valine transporter ATP-binding subunit YP_002384508.1 3496568 R 585054 CDS YP_002384509.1 218550718 7123230 complement(3497332..3498609) 1 NC_011740.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter permease subunit 3498609 livM 7123230 livM Escherichia fergusonii ATCC 35469 leucine/isoleucine/valine transporter permease subunit YP_002384509.1 3497332 R 585054 CDS YP_002384510.1 218550719 7120840 complement(3498606..3499532) 1 NC_011740.1 LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter; branched-chain amino acid transporter permease subunit LivH 3499532 livH 7120840 livH Escherichia fergusonii ATCC 35469 branched-chain amino acid transporter permease subunit LivH YP_002384510.1 3498606 R 585054 CDS YP_002384511.1 218550720 7120837 complement(3499580..3500689) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14702302, 90307651, 2195019, 2649683, 3891753, 4077929, 9298646, 9298646; Product type t : transporter; leucine ABC transporter periplasmic-binding protein 3500689 livK 7120837 livK Escherichia fergusonii ATCC 35469 leucine ABC transporter periplasmic-binding protein YP_002384511.1 3499580 R 585054 CDS YP_002384512.1 218550721 7120839 3501113..3501496 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3501496 yhhK 7120839 yhhK Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384512.1 3501113 D 585054 CDS YP_002384513.1 218550722 7122506 complement(3501697..3502800) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14702302, 90307651, 2195019, 2649682, 328304, 3891753, 4077929, 9298646, 10972807; Product type t : transporter; leucine/isoleucine/valine ABC transporter periplasmic-binding protein 3502800 livJ 7122506 livJ Escherichia fergusonii ATCC 35469 leucine/isoleucine/valine ABC transporter periplasmic-binding protein YP_002384513.1 3501697 R 585054 CDS YP_002384514.1 218550723 7120838 complement(3503072..3503926) 1 NC_011740.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 3503926 rpoH 7120838 rpoH Escherichia fergusonii ATCC 35469 RNA polymerase factor sigma-32 YP_002384514.1 3503072 R 585054 CDS YP_002384515.1 218550724 7121123 complement(3504171..3505229) 1 NC_011740.1 ABC transporter, membrane protein; cell division protein FtsX 3505229 ftsX 7121123 ftsX Escherichia fergusonii ATCC 35469 cell division protein FtsX YP_002384515.1 3504171 R 585054 CDS YP_002384516.1 218550725 7120151 complement(3505222..3505890) 1 NC_011740.1 ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions; cell division protein FtsE 3505890 ftsE 7120151 ftsE Escherichia fergusonii ATCC 35469 cell division protein FtsE YP_002384516.1 3505222 R 585054 CDS YP_002384517.1 218550726 7123111 complement(3505893..3507431) 1 NC_011740.1 signal recognition protein receptor; functions in the targeting and insertion of membrane proteins; cell division protein FtsY 3507431 ftsY 7123111 ftsY Escherichia fergusonii ATCC 35469 cell division protein FtsY YP_002384517.1 3505893 R 585054 CDS YP_002384518.1 218550727 7123653 3507581..3508177 1 NC_011740.1 catalyzes the methylation of 16S rRNA at position G966; 16S rRNA m(2)G966-methyltransferase 3508177 rsmD 7123653 rsmD Escherichia fergusonii ATCC 35469 16S rRNA m(2)G966-methyltransferase YP_002384518.1 3507581 D 585054 CDS YP_002384519.1 218550728 7122503 3508044..3508436 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3508436 7122503 EFER_3439 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384519.1 3508044 D 585054 CDS YP_002384520.1 218550729 7122470 complement(3508439..3508798) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3508798 yhhM 7122470 yhhM Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384520.1 3508439 R 585054 CDS YP_002384521.1 218550730 7122507 3508939..3509565 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3509565 yhhN 7122507 yhhN Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384521.1 3508939 D 585054 CDS YP_002384522.1 218550731 7124052 3509639..3511840 1 NC_011740.1 P-type ATPase involved in the export of lead, cadmium, zinc and mercury; zinc/cadmium/mercury/lead-transporting ATPase 3511840 zntA 7124052 zntA Escherichia fergusonii ATCC 35469 zinc/cadmium/mercury/lead-transporting ATPase YP_002384522.1 3509639 D 585054 CDS YP_002384523.1 218550732 7119773 3511877..3512443 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3512443 7119773 EFER_3443 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384523.1 3511877 D 585054 CDS YP_002384524.1 218550733 7122471 complement(3512556..3512801) 1 NC_011740.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA 3512801 tusA 7122471 tusA Escherichia fergusonii ATCC 35469 sulfur transfer protein SirA YP_002384524.1 3512556 R 585054 CDS YP_002384525.1 218550734 7124071 3513005..3513670 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3513670 yhhQ 7124071 yhhQ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384525.1 3513005 D 585054 CDS YP_002384526.1 218550735 7122508 3513689..3514300 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12558182, 8752353; Product type t : transporter; hypothetical protein 3514300 dcrB 7122508 dcrB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384526.1 3513689 D 585054 CDS YP_002384527.1 218550736 7122872 complement(3514304..3515551) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter 3515551 yhhS 7122872 yhhS Escherichia fergusonii ATCC 35469 transporter YP_002384527.1 3514304 R 585054 CDS YP_002384528.1 218550737 7122509 3515641..3516690 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3516690 yhhT 7122509 yhhT Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384528.1 3515641 D 585054 CDS YP_002384529.1 218550738 7122510 3517082..3517474 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; lipoprotein 3517474 7122510 EFER_3449 Escherichia fergusonii ATCC 35469 lipoprotein YP_002384529.1 3517082 D 585054 CDS YP_002384530.1 218550739 7124044 3517535..3518602 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; methyltransferase 3518602 7124044 EFER_3450 Escherichia fergusonii ATCC 35469 methyltransferase YP_002384530.1 3517535 D 585054 CDS YP_002384531.1 218550740 7124045 3518642..3519367 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3519367 7124045 EFER_3451 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384531.1 3518642 D 585054 CDS YP_002384532.1 218550741 7122472 3519346..3520179 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; 1-acylglycerol-3-phosphate O-acyltransferase 3520179 7122472 EFER_3452 Escherichia fergusonii ATCC 35469 1-acylglycerol-3-phosphate O-acyltransferase YP_002384532.1 3519346 D 585054 CDS YP_002384533.1 218550742 7122473 3519968..3520417 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; acyl carrier protein component 3520417 7122473 EFER_3453 Escherichia fergusonii ATCC 35469 acyl carrier protein component YP_002384533.1 3519968 D 585054 CDS YP_002384534.1 218550743 7122474 3520429..3520680 1 NC_011740.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 3520680 7122474 EFER_3454 Escherichia fergusonii ATCC 35469 acyl carrier protein YP_002384534.1 3520429 D 585054 CDS YP_002384535.1 218550744 7122475 3520685..3521266 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 3521266 7122475 EFER_3455 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384535.1 3520685 D 585054 CDS YP_002384536.1 218550745 7123485 3521224..3522624 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; fatty acid degradation enzyme 3522624 7123485 EFER_3456 Escherichia fergusonii ATCC 35469 fatty acid degradation enzyme YP_002384536.1 3521224 D 585054 CDS YP_002384537.1 218550746 7123486 3522581..3522964 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; fatty acid degradation enzyme 3522964 7123486 EFER_3457 Escherichia fergusonii ATCC 35469 fatty acid degradation enzyme YP_002384537.1 3522581 D 585054 CDS YP_002384538.1 218550747 7122476 3522955..3524631 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; acyltransferase 3524631 7122476 EFER_3458 Escherichia fergusonii ATCC 35469 acyltransferase YP_002384538.1 3522955 D 585054 CDS YP_002384539.1 218550748 7122477 3524635..3525057 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; thioesterase 3525057 7122477 EFER_3459 Escherichia fergusonii ATCC 35469 thioesterase YP_002384539.1 3524635 D 585054 CDS YP_002384540.1 218550749 7122478 3525054..3525659 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; outer membrane lipoprotein carrier protein 3525659 7122478 EFER_3460 Escherichia fergusonii ATCC 35469 outer membrane lipoprotein carrier protein YP_002384540.1 3525054 D 585054 CDS YP_002384541.1 218550750 7122479 3525628..3527946 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter 3527946 7122479 EFER_3461 Escherichia fergusonii ATCC 35469 transporter YP_002384541.1 3525628 D 585054 CDS YP_002384542.1 218550751 7122480 3527943..3528527 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; lipoprotein 3528527 7122480 EFER_3462 Escherichia fergusonii ATCC 35469 lipoprotein YP_002384542.1 3527943 D 585054 CDS YP_002384543.1 218550752 7122481 3528520..3529698 1 NC_011740.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 3529698 7122481 EFER_3463 Escherichia fergusonii ATCC 35469 3-oxoacyl-ACP synthase YP_002384543.1 3528520 D 585054 CDS YP_002384544.1 218550753 7122482 3529695..3530144 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; 3-hydroxy-fatty acyl-(acyl carrier protein) dehydratase 3530144 7122482 EFER_3464 Escherichia fergusonii ATCC 35469 3-hydroxy-fatty acyl-(acyl carrier protein) dehydratase YP_002384544.1 3529695 D 585054 CDS YP_002384545.1 218550754 7124046 3530159..3530890 1 NC_011740.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 3530890 fabG 7124046 fabG Escherichia fergusonii ATCC 35469 3-ketoacyl-ACP reductase YP_002384545.1 3530159 D 585054 CDS YP_002384546.1 218550755 7122483 3530887..3532116 1 NC_011740.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 3532116 7122483 EFER_3466 Escherichia fergusonii ATCC 35469 3-oxoacyl-(acyl carrier protein) synthase II YP_002384546.1 3530887 D 585054 CDS YP_002384547.1 218550756 7122484 3532118..3532702 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; holo-(acyl carrier protein) synthase 2 3532702 acpT 7122484 acpT Escherichia fergusonii ATCC 35469 holo-(acyl carrier protein) synthase 2 YP_002384547.1 3532118 D 585054 CDS YP_002384548.1 218550757 7122264 3532742..3533143 1 NC_011740.1 Inhibits transcription at high concentrations of nickel; nickel responsive regulator 3533143 nikR 7122264 nikR Escherichia fergusonii ATCC 35469 nickel responsive regulator YP_002384548.1 3532742 D 585054 CDS YP_002384549.1 218550758 7123736 3533247..3534113 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 3534113 7123736 EFER_3469 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384549.1 3533247 D 585054 CDS YP_002384550.1 218550759 7121442 3534453..3535208 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator 3535208 7121442 EFER_3470 Escherichia fergusonii ATCC 35469 transcriptional regulator YP_002384550.1 3534453 D 585054 CDS YP_002384551.1 218550760 7120145 3535233..3535706 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; phosphotransferase system enzyme subunit IIA 3535706 7120145 EFER_3471 Escherichia fergusonii ATCC 35469 phosphotransferase system enzyme subunit IIA YP_002384551.1 3535233 D 585054 CDS YP_002384552.1 218550761 7120269 3535703..3535984 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; phosphotransferase system enzyme IIB 3535984 7120269 EFER_3472 Escherichia fergusonii ATCC 35469 phosphotransferase system enzyme IIB YP_002384552.1 3535703 D 585054 CDS YP_002384553.1 218550762 7120270 3536031..3537419 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; phosphotransferase system permease IIC 3537419 7120270 EFER_3473 Escherichia fergusonii ATCC 35469 phosphotransferase system permease IIC YP_002384553.1 3536031 D 585054 CDS YP_002384554.1 218550763 7120271 3537412..3538920 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; carbohydrate kinase 3538920 7120271 EFER_3474 Escherichia fergusonii ATCC 35469 carbohydrate kinase YP_002384554.1 3537412 D 585054 CDS YP_002384555.1 218550764 7120272 3538910..3539179 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; phosphocarrier HPr protein of a carbohydrate phosphotransferase system 3539179 7120272 EFER_3475 Escherichia fergusonii ATCC 35469 phosphocarrier HPr protein of a carbohydrate phosphotransferase system YP_002384555.1 3538910 D 585054 CDS YP_002384556.1 218550765 7123131 3539210..3540061 1 NC_011740.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis; fructose-1,6-bisphosphate aldolase 3540061 gatY 7123131 gatY Escherichia fergusonii ATCC 35469 fructose-1,6-bisphosphate aldolase YP_002384556.1 3539210 D 585054 CDS YP_002384557.1 218550766 7120273 complement(3540152..3541276) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter membrane protein 3541276 yhhJ 7120273 yhhJ Escherichia fergusonii ATCC 35469 ABC transporter membrane protein YP_002384557.1 3540152 R 585054 CDS YP_002384558.1 218550767 7122505 complement(3541276..3544011) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20074572; Product type e : enzyme; ribosome-associated ATPase/membrane protein 3544011 rbbA 7122505 rbbA Escherichia fergusonii ATCC 35469 ribosome-associated ATPase/membrane protein YP_002384558.1 3541276 R 585054 CDS YP_002384559.1 218550768 7123467 complement(3544008..3545075) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; HlyD family secretion protein 3545075 yhiI 7123467 yhiI Escherichia fergusonii ATCC 35469 HlyD family secretion protein YP_002384559.1 3544008 R 585054 CDS YP_002384560.1 218550769 7123489 3545808..3546860 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3546860 yhiM 7123489 yhiM Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384560.1 3545808 D 585054 CDS YP_002384561.1 218550770 7123490 3547731..3556922 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17220313, 15522082; Product type f : factor; adhesin for cattle intestine colonization 3556922 siiEB 7123490 siiEB Escherichia fergusonii ATCC 35469 adhesin for cattle intestine colonization YP_002384561.1 3547731 D 585054 CDS YP_002384562.1 218550771 7121787 3556999..3558402 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17220313, 15522082, 2905265; Product type t : transporter; outer membrane export protein 3558402 siiCB 7121787 siiCB Escherichia fergusonii ATCC 35469 outer membrane export protein YP_002384562.1 3556999 D 585054 CDS YP_002384563.1 218550772 7123375 3558399..3560576 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17220313, 15522082, 2905265, 2185213; Product type t : transporter; type I secretion membrane protein, ATP-binding protein, protein export 3560576 siiBB 7123375 siiBB Escherichia fergusonii ATCC 35469 type I secretion membrane protein, ATP-binding protein, protein export YP_002384563.1 3558399 D 585054 CDS YP_002384564.1 218550773 7121783 3560557..3561747 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 17220313, 15522082, 2905265; Product type t : transporter; HlyD family secretion type I protein 3561747 siiDB 7121783 siiDB Escherichia fergusonii ATCC 35469 HlyD family secretion type I protein YP_002384564.1 3560557 D 585054 CDS YP_002384565.1 218550774 7123923 complement(3561870..3563063) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; oxidoreductase 3563063 yhiN 7123923 yhiN Escherichia fergusonii ATCC 35469 oxidoreductase YP_002384565.1 3561870 R 585054 CDS YP_002384566.1 218550775 7122515 3563293..3564792 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87014120; Product type t : transporter; phosphate transporter, low-affinity 3564792 pitA 7122515 pitA Escherichia fergusonii ATCC 35469 phosphate transporter, low-affinity YP_002384566.1 3563293 D 585054 CDS YP_002384567.1 218550776 7123100 complement(3564844..3565179) 1 NC_011740.1 ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspB 3565179 yhiO 7123100 yhiO Escherichia fergusonii ATCC 35469 universal stress protein UspB YP_002384567.1 3564844 R 585054 CDS YP_002384568.1 218550777 7122516 3565572..3566006 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12732303, 93086426, 93308072, 94203056, 10499297, 10652104, 10931298, 11157932, 1453957, 8506346, 8932299, 9298646, 9405142; Product type f : factor; universal stress global response regulator 3566006 uspA 7122516 uspA Escherichia fergusonii ATCC 35469 universal stress global response regulator YP_002384568.1 3565572 D 585054 CDS YP_002384569.1 218550778 7122643 3566250..3567719 1 NC_011740.1 member of the POT family of peptide transporters; probable proton-dependent peptide transporter function; inner membrane transporter YhiP 3567719 yhiP 7122643 yhiP Escherichia fergusonii ATCC 35469 inner membrane transporter YhiP YP_002384569.1 3566250 D 585054 CDS YP_002384570.1 218550779 7123491 complement(3567768..3568520) 1 NC_011740.1 predicted SAM-dependent methyltransferase; methyltransferase 3568520 yhiQ 7123491 yhiQ Escherichia fergusonii ATCC 35469 methyltransferase YP_002384570.1 3567768 R 585054 CDS YP_002384571.1 218550780 7123492 complement(3568528..3570570) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92394891, 1325967, 8366062; Product type e : enzyme; oligopeptidase A 3570570 prlC 7123492 prlC Escherichia fergusonii ATCC 35469 oligopeptidase A YP_002384571.1 3568528 R 585054 CDS YP_002384572.1 218550781 7120129 3570773..3571615 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11591672; Product type pe : enzyme; DNA (exogenous) processing protein 3571615 yhiR 7120129 yhiR Escherichia fergusonii ATCC 35469 DNA (exogenous) processing protein YP_002384572.1 3570773 D 585054 CDS YP_002384573.1 218550782 7122517 3571687..3573039 1 NC_011740.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 3573039 gor 7122517 gor Escherichia fergusonii ATCC 35469 glutathione reductase YP_002384573.1 3571687 D 585054 CDS YP_002384574.1 218550783 7120602 3573198..3573377 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 3573377 7120602 EFER_3494 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384574.1 3573198 D 585054 CDS YP_002384575.1 218550784 7120274 3573256..3573423 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3573423 7120274 EFER_3495 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384575.1 3573256 D 585054 CDS YP_002384576.1 218550785 7120275 3573448..3573672 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3573672 7120275 EFER_3496 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384576.1 3573448 D 585054 CDS YP_002384577.1 218550786 7120276 3573918..3574271 1 NC_011740.1 regulates the expression of of the arsRBC involved in resistance to arsenic; DNA-binding transcriptional repressor ArsR 3574271 arsR 7120276 arsR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional repressor ArsR YP_002384577.1 3573918 D 585054 CDS YP_002384578.1 218550787 7120555 3574326..3575615 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15004242, 95355341, 1535622, 7721697; Product type t : transporter; arsenite/antimonite transporter 3575615 arsB 7120555 arsB Escherichia fergusonii ATCC 35469 arsenite/antimonite transporter YP_002384578.1 3574326 D 585054 CDS YP_002384579.1 218550788 7123718 3575628..3576053 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95355341, 7721697; Product type e : enzyme; arsenate reductase 3576053 arsC 7123718 arsC Escherichia fergusonii ATCC 35469 arsenate reductase YP_002384579.1 3575628 D 585054 CDS YP_002384580.1 218550789 7123719 complement(3576074..3576394) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3576394 7123719 EFER_3500 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384580.1 3576074 R 585054 CDS YP_002384581.1 218550790 7123671 3576490..3577503 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 3577503 7123671 EFER_3501 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384581.1 3576490 D 585054 CDS YP_002384582.1 218550791 7120277 3577746..3579395 1 NC_011740.1 cytoplasmic; catalyzes the hydrolysis of trehalose to glucose; trehalase 3579395 treF 7120277 treF Escherichia fergusonii ATCC 35469 trehalase YP_002384582.1 3577746 D 585054 CDS YP_002384583.1 218550792 7122156 complement(3579428..3580111) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; HTH-type transcriptional regulator YhjB 3580111 yhjB 7122156 yhjB Escherichia fergusonii ATCC 35469 HTH-type transcriptional regulator YhjB YP_002384583.1 3579428 R 585054 CDS YP_002384584.1 218550793 7122518 3580434..3580607 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3580607 7122518 EFER_3504 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384584.1 3580434 D 585054 CDS YP_002384585.1 218550794 7120278 3580564..3581619 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3581619 yhjD 7120278 yhjD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384585.1 3580564 D 585054 CDS YP_002384586.1 218550795 7122519 3581893..3583215 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter 3583215 yhjE 7122519 yhjE Escherichia fergusonii ATCC 35469 transporter YP_002384586.1 3581893 D 585054 CDS YP_002384587.1 218550796 7122520 complement(3583256..3585316) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; outer membrane biogenesis protein 3585316 yhjG 7122520 yhjG Escherichia fergusonii ATCC 35469 outer membrane biogenesis protein YP_002384587.1 3583256 R 585054 CDS YP_002384588.1 218550797 7124053 complement(3585383..3586150) 1 NC_011740.1 in Escherichia coli this protein is involved in flagellar function; EAL domain-containing protein 3586150 yhjH 7124053 yhjH Escherichia fergusonii ATCC 35469 EAL domain-containing protein YP_002384588.1 3585383 R 585054 CDS YP_002384589.1 218550798 7124054 3586356..3587285 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 4359651, 13813474; Product type e : enzyme; ketodeoxygluconokinase 3587285 kdgK 7124054 kdgK Escherichia fergusonii ATCC 35469 ketodeoxygluconokinase YP_002384589.1 3586356 D 585054 CDS YP_002384590.1 218550799 7120803 3587375..3588595 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3588595 7120803 EFER_3510 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384590.1 3587375 D 585054 CDS YP_002384591.1 218550800 7123672 3588357..3590576 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3590576 7123672 EFER_3511 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384591.1 3588357 D 585054 CDS YP_002384592.1 218550801 7120279 complement(3591448..3592944) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9298646; Product type pe : enzyme; zinc-dependent peptidase 3592944 yhjJ 7120279 yhjJ Escherichia fergusonii ATCC 35469 zinc-dependent peptidase YP_002384592.1 3591448 R 585054 CDS YP_002384593.1 218550802 7122521 complement(3593166..3594452) 1 NC_011740.1 involved in the transport of C4-dicarboxylates across the membrane; C4-dicarboxylate transporter DctA 3594452 dctA 7122521 dctA Escherichia fergusonii ATCC 35469 C4-dicarboxylate transporter DctA YP_002384593.1 3593166 R 585054 CDS YP_002384594.1 218550803 7122873 complement(3594621..3596570) 1 NC_011740.1 HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a phosphodiesterase protein from E. coli; phosphodiesterase 3596570 yhjK 7122873 yhjK Escherichia fergusonii ATCC 35469 phosphodiesterase YP_002384594.1 3594621 R 585054 CDS YP_002384595.1 218550804 7122522 complement(3596685..3600158) 1 NC_011740.1 cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA; cellulose synthase subunit BcsC 3600158 bcsC 7122522 bcsC Escherichia fergusonii ATCC 35469 cellulose synthase subunit BcsC YP_002384595.1 3596685 R 585054 CDS YP_002384596.1 218550805 7121652 complement(3600140..3601246) 1 NC_011740.1 catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; endo-1,4-D-glucanase 3601246 bcsZ 7121652 bcsZ Escherichia fergusonii ATCC 35469 endo-1,4-D-glucanase YP_002384596.1 3600140 R 585054 CDS YP_002384597.1 218550806 7123902 complement(3601253..3603592) 1 NC_011740.1 binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); cellulose synthase regulator protein 3603592 bcsB 7123902 bcsB Escherichia fergusonii ATCC 35469 cellulose synthase regulator protein YP_002384597.1 3601253 R 585054 CDS YP_002384598.1 218550807 7121651 complement(3603603..3606221) 1 NC_011740.1 polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis; cellulose synthase catalytic subunit 3606221 bcsA 7121651 bcsA Escherichia fergusonii ATCC 35469 cellulose synthase catalytic subunit YP_002384598.1 3603603 R 585054 CDS YP_002384599.1 218550808 7121649 complement(3606218..3606985) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9054507; Product type pe : enzyme; chromosome partitioning ATPase 3606985 yhjQ 7121649 yhjQ Escherichia fergusonii ATCC 35469 chromosome partitioning ATPase YP_002384599.1 3606218 R 585054 CDS YP_002384600.1 218550809 7122523 complement(3606997..3607185) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3607185 yhjR 7122523 yhjR Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384600.1 3606997 R 585054 CDS YP_002384601.1 218550810 7122524 3607472..3609031 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11929533, 11260463; Product type pe : enzyme; cellulose biosynthesis protease 3609031 bcsE 7122524 bcsE Escherichia fergusonii ATCC 35469 cellulose biosynthesis protease YP_002384601.1 3607472 D 585054 CDS YP_002384602.1 218550811 7121653 3609028..3609219 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3609219 bcsF 7121653 bcsF Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384602.1 3609028 D 585054 CDS YP_002384603.1 218550812 7121654 3609216..3610895 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11929533, 11260463; Product type pe : enzyme; cellulose biosynthesis endoglucanase 3610895 bcsG 7121654 bcsG Escherichia fergusonii ATCC 35469 cellulose biosynthesis endoglucanase YP_002384603.1 3609216 D 585054 CDS YP_002384604.1 218550813 7121655 complement(3611464..3611715) 1 NC_011740.1 Small toxic polypeptide ldrD 3611715 7121655 EFER_3527 Escherichia fergusonii ATCC 35469 Small toxic polypeptide ldrD YP_002384604.1 3611464 R 585054 CDS YP_002384605.1 218550814 7123673 3611815..3612057 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3612057 7123673 EFER_3528 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384605.1 3611815 D 585054 CDS YP_002384606.1 218550815 7120280 complement(3611946..3612188) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12123448; Product type f : factor; toxic polypeptide, small 3612188 ldrD 7120280 ldrD Escherichia fergusonii ATCC 35469 toxic polypeptide, small YP_002384606.1 3611946 R 585054 CDS YP_002384607.1 218550816 7120820 3612298..3612540 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3612540 7120820 EFER_3530 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384607.1 3612298 D 585054 CDS YP_002384608.1 218550817 7120281 complement(3612429..3612536) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12123448; Product type f : factor; toxic polypeptide, small 3612536 ldrD 7120281 ldrD Escherichia fergusonii ATCC 35469 toxic polypeptide, small YP_002384608.1 3612429 R 585054 CDS YP_002384609.1 218550818 7122357 3612957..3614168 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15901718; Product type e : enzyme; methionine gamma-lyase 3614168 7122357 EFER_3533 Escherichia fergusonii ATCC 35469 methionine gamma-lyase YP_002384609.1 3612957 D 585054 CDS YP_002384610.1 218550819 7120282 complement(3614172..3614396) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3614396 7120282 EFER_3534 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384610.1 3614172 R 585054 CDS YP_002384611.1 218550820 7120283 3614418..3615716 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15901718; Product type t : transporter; transporter 3615716 yhjV 7120283 yhjV Escherichia fergusonii ATCC 35469 transporter YP_002384611.1 3614418 D 585054 CDS YP_002384612.1 218550821 7124055 complement(3615732..3617063) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1779763; Product type pr : regulator; transcriptional regulator 3617063 7124055 EFER_3536 Escherichia fergusonii ATCC 35469 transcriptional regulator YP_002384612.1 3615732 R 585054 CDS YP_002384613.1 218550822 7123132 complement(3617106..3618110) 1 NC_011740.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding subunit 3618110 dppF 7123132 dppF Escherichia fergusonii ATCC 35469 dipeptide transporter ATP-binding subunit YP_002384613.1 3617106 R 585054 CDS YP_002384614.1 218550823 7122919 complement(3618107..3619090) 1 NC_011740.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding subunit 3619090 dppD 7122919 dppD Escherichia fergusonii ATCC 35469 dipeptide transporter ATP-binding subunit YP_002384614.1 3618107 R 585054 CDS YP_002384615.1 218550824 7122918 complement(3619101..3620003) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7536291; Product type t : transporter; dipeptide transporter 3620003 dppC 7122918 dppC Escherichia fergusonii ATCC 35469 dipeptide transporter YP_002384615.1 3619101 R 585054 CDS YP_002384616.1 218550825 7123554 complement(3620013..3621032) 1 NC_011740.1 transports peptides consisting of two or three amino acids; dipeptide transporter permease DppB 3621032 dppB 7123554 dppB Escherichia fergusonii ATCC 35469 dipeptide transporter permease DppB YP_002384616.1 3620013 R 585054 CDS YP_002384617.1 218550826 7122917 complement(3621183..3622790) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91100289, 92065799, 1702779, 1956284, 7536291, 8527431, 8563629, 9298646, 9600841, 9740056, 10972807; Product type t : transporter; dipeptide ABC transporter substrate-binding protein 3622790 dppA 7122917 dppA Escherichia fergusonii ATCC 35469 dipeptide ABC transporter substrate-binding protein YP_002384617.1 3621183 R 585054 CDS YP_002384618.1 218550827 7123637 complement(3623827..3625683) 1 NC_011740.1 catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide; phosphoethanolamine transferase 3625683 yhjW 7123637 yhjW Escherichia fergusonii ATCC 35469 phosphoethanolamine transferase YP_002384618.1 3623827 R 585054 CDS YP_002384619.1 218550828 7122525 complement(3625867..3627222) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter 3627222 yhjX 7122525 yhjX Escherichia fergusonii ATCC 35469 transporter YP_002384619.1 3625867 R 585054 CDS YP_002384620.1 218550829 7122526 complement(3627296..3628039) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8449874; Product type pe : enzyme; lipase 3628039 yhjY 7122526 yhjY Escherichia fergusonii ATCC 35469 lipase YP_002384620.1 3627296 R 585054 CDS YP_002384621.1 218550830 7122527 3628033..3628719 1 NC_011740.1 constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine; 3-methyladenine DNA glycosylase 3628719 tag 7122527 tag Escherichia fergusonii ATCC 35469 3-methyladenine DNA glycosylase YP_002384621.1 3628033 D 585054 CDS YP_002384622.1 218550831 7121971 3628604..3629149 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2180922; Product type pe : enzyme; hypothetical protein 3629149 yiaC 7121971 yiaC Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384622.1 3628604 D 585054 CDS YP_002384623.1 218550832 7122529 complement(3629118..3631397) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 82119950, 90202748, 2180922, 374979; Product type e : enzyme; biotin sulfoxide reductase 3631397 bisC 7122529 bisC Escherichia fergusonii ATCC 35469 biotin sulfoxide reductase YP_002384623.1 3629118 R 585054 CDS YP_002384624.1 218550833 7123905 3631604..3632263 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; outer membrane lipoprotein 3632263 yiaD 7123905 yiaD Escherichia fergusonii ATCC 35469 outer membrane lipoprotein YP_002384624.1 3631604 D 585054 CDS YP_002384625.1 218550834 7122530 3632309..3633385 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1639817; Product type pr : regulator; LacI family transcriptional regulator 3633385 7122530 EFER_3550 Escherichia fergusonii ATCC 35469 LacI family transcriptional regulator YP_002384625.1 3632309 D 585054 CDS YP_002384626.1 218550835 7120284 3633485..3634234 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10931350; Product type pe : enzyme; sugar or sugar phosphate isomerase 3634234 7120284 EFER_3551 Escherichia fergusonii ATCC 35469 sugar or sugar phosphate isomerase YP_002384626.1 3633485 D 585054 CDS YP_002384627.1 218550836 7120285 3634209..3635177 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; 2-dehydro-3-deoxygluconokinase 3635177 7120285 EFER_3552 Escherichia fergusonii ATCC 35469 2-dehydro-3-deoxygluconokinase YP_002384627.1 3634209 D 585054 CDS YP_002384628.1 218550837 7120286 3635272..3636552 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7592429; Product type pt : transporter; carboxylate-containing product, possibly ketogluconate transporter 3636552 7120286 EFER_3553 Escherichia fergusonii ATCC 35469 carboxylate-containing product, possibly ketogluconate transporter YP_002384628.1 3635272 D 585054 CDS YP_002384629.1 218550838 7120287 3636574..3637548 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15801772, 11237876, 99030322, 99357626, 9298646, 9811658; Product type e : enzyme; 2-oxo-carboxylic acid reductase 3637548 tiaE 7120287 tiaE Escherichia fergusonii ATCC 35469 2-oxo-carboxylic acid reductase YP_002384629.1 3636574 D 585054 CDS YP_002384630.1 218550839 7122131 complement(3637641..3638411) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3638411 yiaF 7122131 yiaF Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384630.1 3637641 R 585054 CDS YP_002384631.1 218550840 7122531 3638759..3640159 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 7961399; Product type t : transporter; aromatic acid transporter 3640159 7122531 EFER_3556 Escherichia fergusonii ATCC 35469 aromatic acid transporter YP_002384631.1 3638759 D 585054 CDS YP_002384632.1 218550841 7123133 3640409..3640699 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator 3640699 yiaG 7123133 yiaG Escherichia fergusonii ATCC 35469 transcriptional regulator YP_002384632.1 3640409 D 585054 CDS YP_002384633.1 218550842 7123493 3640981..3641193 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20345064, 90115858, 94293754, 94293756, 99177178, 10696873, 1597410, 1961761, 2404279, 7515185, 8197194, 9405743, 9439003, 9692981; Product type f : factor; major cold shock protein 3641193 cspA 7123493 cspA Escherichia fergusonii ATCC 35469 major cold shock protein YP_002384633.1 3640981 D 585054 CDS YP_002384634.1 218550843 7122817 complement(3641247..3641618) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3641618 7122817 EFER_3559 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384634.1 3641247 R 585054 CDS YP_002384635.1 218550844 7120288 complement(3642252..3644321) 1 NC_011740.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 3644321 glyS 7120288 glyS Escherichia fergusonii ATCC 35469 glycyl-tRNA synthetase subunit beta YP_002384635.1 3642252 R 585054 CDS YP_002384636.1 218550845 7120592 complement(3644331..3645242) 1 NC_011740.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 3645242 glyQ 7120592 glyQ Escherichia fergusonii ATCC 35469 glycyl-tRNA synthetase subunit alpha YP_002384636.1 3644331 R 585054 CDS YP_002384637.1 218550846 7120591 complement(3645338..3645640) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3645640 ysaB 7120591 ysaB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384637.1 3645338 R 585054 CDS YP_002384638.1 218550847 7119756 3645809..3646804 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3646804 yiaH 7119756 yiaH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384638.1 3645809 D 585054 CDS YP_002384639.1 218550848 7123494 complement(3646869..3647252) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 15919996; Product type m : membrane component; hypothetical protein 3647252 yiaB 7123494 yiaB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384639.1 3646869 R 585054 CDS YP_002384640.1 218550849 7122528 complement(3647383..3648846) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6330500, 92366447, 95050816, 6320721; Product type e : enzyme; xylulokinase 3648846 xylB 7122528 xylB Escherichia fergusonii ATCC 35469 xylulokinase YP_002384640.1 3647383 R 585054 CDS YP_002384641.1 218550850 7122389 complement(3648910..3650232) 1 NC_011740.1 catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 3650232 xylA 7122389 xylA Escherichia fergusonii ATCC 35469 xylose isomerase YP_002384641.1 3648910 R 585054 CDS YP_002384642.1 218550851 7122388 3650444..3651718 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6330500, 94316500; Product type r : regulator; DNA-binding transcriptional activator 3651718 xylR 7122388 xylR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional activator YP_002384642.1 3650444 D 585054 CDS YP_002384643.1 218550852 7122391 complement(3651772..3652596) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1544897; hypothetical protein 3652596 bax 7122391 bax Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384643.1 3651772 R 585054 CDS YP_002384644.1 218550853 7121646 3652839..3654947 1 NC_011740.1 periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds; periplasmic alpha-amylase 3654947 malS 7121646 malS Escherichia fergusonii ATCC 35469 periplasmic alpha-amylase YP_002384644.1 3652839 D 585054 CDS YP_002384645.1 218550854 7121226 3655123..3656376 1 NC_011740.1 transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase 3656376 avtA 7121226 avtA Escherichia fergusonii ATCC 35469 valine--pyruvate transaminase YP_002384645.1 3655123 D 585054 CDS YP_002384646.1 218550855 7123901 complement(3656413..3657006) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; hydrogenase, 4Fe-4S ferredoxin-type component 3657006 yiaI 7123901 yiaI Escherichia fergusonii ATCC 35469 hydrogenase, 4Fe-4S ferredoxin-type component YP_002384646.1 3656413 R 585054 CDS YP_002384647.1 218550856 7122532 complement(3657003..3657875) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 20372646, 9826648; Product type r : regulator; DNA-binding transcriptional repressor 3657875 yiaJ 7122532 yiaJ Escherichia fergusonii ATCC 35469 DNA-binding transcriptional repressor YP_002384647.1 3657003 R 585054 CDS YP_002384648.1 218550857 7122533 3658035..3659033 1 NC_011740.1 NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate; 2,3-diketo-L-gulonate reductase 3659033 yiaK 7122533 yiaK Escherichia fergusonii ATCC 35469 2,3-diketo-L-gulonate reductase YP_002384648.1 3658035 D 585054 CDS YP_002384649.1 218550858 7122534 3659045..3659512 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 21617392; hypothetical protein 3659512 yiaL 7122534 yiaL Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384649.1 3659045 D 585054 CDS YP_002384650.1 218550859 7122535 3659630..3660103 1 NC_011740.1 membrane-spanning protein involved in uptake of 2,3-diketo-L-gulonate; part of the tri-partite ATP-independent periplasmic transport system (TRAP) YiaMNO; 2,3-diketo-L-gulonate TRAP transporter small permease YiaM 3660103 yiaM 7122535 yiaM Escherichia fergusonii ATCC 35469 2,3-diketo-L-gulonate TRAP transporter small permease YiaM YP_002384650.1 3659630 D 585054 CDS YP_002384651.1 218550860 7124056 3660106..3661383 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14668138, 21617392; Product type t : transporter; transporter 3661383 yiaN 7124056 yiaN Escherichia fergusonii ATCC 35469 transporter YP_002384651.1 3660106 D 585054 CDS YP_002384652.1 218550861 7124057 3661396..3662382 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14668138, 21617392; Product type t : transporter; transporter 3662382 yiaO 7124057 yiaO Escherichia fergusonii ATCC 35469 transporter YP_002384652.1 3661396 D 585054 CDS YP_002384653.1 218550862 7122536 3662386..3663882 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21617392, 95050816, 7961955; Product type e : enzyme; L-xylulose kinase 3663882 lyxK 7122536 lyxK Escherichia fergusonii ATCC 35469 L-xylulose kinase YP_002384653.1 3662386 D 585054 CDS YP_002384654.1 218550863 7121218 3663879..3664541 1 NC_011740.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate; 3-keto-L-gulonate-6-phosphate decarboxylase 3664541 sgbH 7121218 sgbH Escherichia fergusonii ATCC 35469 3-keto-L-gulonate-6-phosphate decarboxylase YP_002384654.1 3663879 D 585054 CDS YP_002384655.1 218550864 7123921 3664534..3665394 1 NC_011740.1 L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; L-xylulose 5-phosphate 3-epimerase 3665394 sgbU 7123921 sgbU Escherichia fergusonii ATCC 35469 L-xylulose 5-phosphate 3-epimerase YP_002384655.1 3664534 D 585054 CDS YP_002384656.1 218550865 7121778 3665388..3666083 1 NC_011740.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 3666083 sgbE 7121778 sgbE Escherichia fergusonii ATCC 35469 L-ribulose-5-phosphate 4-epimerase YP_002384656.1 3665388 D 585054 CDS YP_002384657.1 218550866 7121777 complement(3666130..3667668) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95286498, 7768815; Product type e : enzyme; aldehyde dehydrogenase B 3667668 aldB 7121777 aldB Escherichia fergusonii ATCC 35469 aldehyde dehydrogenase B YP_002384657.1 3666130 R 585054 CDS YP_002384658.1 218550867 7122292 complement(3667869..3669020) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2935393; Product type e : enzyme; alcohol dehydrogenase 3669020 yiaY 7122292 yiaY Escherichia fergusonii ATCC 35469 alcohol dehydrogenase YP_002384658.1 3667869 R 585054 CDS YP_002384659.1 218550868 7122537 complement(3669210..3671057) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90264431, 91317715, 9315303, 94148228, 2140572, 2531290; Product type f : factor; selenocysteinyl-tRNA-specific translation factor 3671057 selB 7122537 selB Escherichia fergusonii ATCC 35469 selenocysteinyl-tRNA-specific translation factor YP_002384659.1 3669210 R 585054 CDS YP_002384660.1 218550869 7121767 complement(3671054..3672445) 1 NC_011740.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase 3672445 selA 7121767 selA Escherichia fergusonii ATCC 35469 selenocysteine synthase YP_002384660.1 3671054 R 585054 CDS YP_002384661.1 218550870 7121766 complement(3672543..3673151) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8624414; Product type pe : enzyme; glutathione S-transferase 3673151 yibF 7121766 yibF Escherichia fergusonii ATCC 35469 glutathione S-transferase YP_002384661.1 3672543 R 585054 CDS YP_002384662.1 218550871 7124058 complement(3673220..3674356) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3674356 yibH 7124058 yibH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384662.1 3673220 R 585054 CDS YP_002384663.1 218550872 7122539 complement(3674359..3674721) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3674721 yibI 7122539 yibI Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384663.1 3674359 R 585054 CDS YP_002384664.1 218550873 7122540 3674919..3675200 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 3675200 7122540 EFER_3589 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384664.1 3674919 D 585054 CDS YP_002384665.1 218550874 7120289 3675257..3677173 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92052139, 92283796, 94131964, 1946374, 3135464, 3142516, 6309813, 9551558; Product type t : transporter; PTS system mannitol-specific transporter subunit IIABC 3677173 mtlA 7120289 mtlA Escherichia fergusonii ATCC 35469 PTS system mannitol-specific transporter subunit IIABC YP_002384665.1 3675257 D 585054 CDS YP_002384666.1 218550875 7120638 3677268..3678416 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90254197, 1964486, 3135464, 6384188, 8300537, 13295236; Product type e : enzyme; mannitol-1-phosphate 5-dehydrogenase 3678416 mtlD 7120638 mtlD Escherichia fergusonii ATCC 35469 mannitol-1-phosphate 5-dehydrogenase YP_002384666.1 3677268 D 585054 CDS YP_002384667.1 218550876 7120639 3678459..3679004 1 NC_011740.1 Acts as a repressor of the mtlAD operon; mannitol repressor protein 3679004 mtlR 7120639 mtlR Escherichia fergusonii ATCC 35469 mannitol repressor protein YP_002384667.1 3678459 D 585054 CDS YP_002384668.1 218550877 7120640 complement(3679017..3679301) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3679301 7120640 EFER_3593 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384668.1 3679017 R 585054 CDS YP_002384669.1 218550878 7120290 3679512..3679874 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3679874 yibL 7120290 yibL Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384669.1 3679512 D 585054 CDS YP_002384670.1 218550879 7122542 3680406..3681080 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; lipoprotein 3681080 7122542 EFER_3595 Escherichia fergusonii ATCC 35469 lipoprotein YP_002384670.1 3680406 D 585054 CDS YP_002384671.1 218550880 7123134 3681110..3686497 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2117568; Product type pm : membrane component; protein; outer membrane protein 3686497 7123134 EFER_3596 Escherichia fergusonii ATCC 35469 protein; outer membrane protein YP_002384671.1 3681110 D 585054 CDS YP_002384672.1 218550881 7120291 3686925..3688580 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94012541, 11283302, 11785976, 8407843; Product type t : transporter; L-lactate permease 3688580 lldP 7120291 lldP Escherichia fergusonii ATCC 35469 L-lactate permease YP_002384672.1 3686925 D 585054 CDS YP_002384673.1 218550882 7120842 3688580..3689356 1 NC_011740.1 represses the lctPRD operon; DNA-binding transcriptional repressor LldR 3689356 lldR 7120842 lldR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional repressor LldR YP_002384673.1 3688580 D 585054 CDS YP_002384674.1 218550883 7120843 3689353..3690543 1 NC_011740.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 3690543 lldD 7120843 lldD Escherichia fergusonii ATCC 35469 L-lactate dehydrogenase YP_002384674.1 3689353 D 585054 CDS YP_002384675.1 218550884 7120841 3690591..3691064 1 NC_011740.1 member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates; tRNA/rRNA methyltransferase YibK 3691064 yibK 7120841 yibK Escherichia fergusonii ATCC 35469 tRNA/rRNA methyltransferase YibK YP_002384675.1 3690591 D 585054 CDS YP_002384676.1 218550885 7122541 complement(3691117..3691938) 1 NC_011740.1 catalyzes the O-acetylation of serine; serine acetyltransferase 3691938 cysE 7122541 cysE Escherichia fergusonii ATCC 35469 serine acetyltransferase YP_002384676.1 3691117 R 585054 CDS YP_002384677.1 218550886 7122849 complement(3692018..3693037) 1 NC_011740.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 3693037 gpsA 7122849 gpsA Escherichia fergusonii ATCC 35469 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_002384677.1 3692018 R 585054 CDS YP_002384678.1 218550887 7120612 complement(3693037..3693504) 1 NC_011740.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be to SecA; preprotein translocase subunit SecB 3693504 secB 7120612 secB Escherichia fergusonii ATCC 35469 preprotein translocase subunit SecB YP_002384678.1 3693037 R 585054 CDS YP_002384679.1 218550888 7123372 complement(3693566..3693817) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94316500, 95024051, 99175138, 11031118, 7937896, 8636094, 9973569; Product type c : carrier; glutaredoxin 3 3693817 grxC 7123372 grxC Escherichia fergusonii ATCC 35469 glutaredoxin 3 YP_002384679.1 3693566 R 585054 CDS YP_002384680.1 218550889 7120618 complement(3693846..3694277) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; rhodanese-related sulfurtransferase 3694277 yibN 7120618 yibN Escherichia fergusonii ATCC 35469 rhodanese-related sulfurtransferase YP_002384680.1 3693846 R 585054 CDS YP_002384681.1 218550890 7122543 3694523..3696067 1 NC_011740.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 3696067 gpmI 7122543 gpmI Escherichia fergusonii ATCC 35469 phosphoglyceromutase YP_002384681.1 3694523 D 585054 CDS YP_002384682.1 218550891 7120610 3696101..3697360 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12113939, 21972773; Product type cp : cell process; hypothetical protein 3697360 envC 7120610 envC Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384682.1 3696101 D 585054 CDS YP_002384683.1 218550892 7124134 3697364..3698320 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; polysaccharide deacetylase 3698320 yibQ 7124134 yibQ Escherichia fergusonii ATCC 35469 polysaccharide deacetylase YP_002384683.1 3697364 D 585054 CDS YP_002384684.1 218550893 7122544 complement(3698307..3699341) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15659689, 2647748; Product type pe : enzyme; glycosyl transferase family protein 3699341 yibD 7122544 yibD Escherichia fergusonii ATCC 35469 glycosyl transferase family protein YP_002384684.1 3698307 R 585054 CDS YP_002384685.1 218550894 7122538 complement(3699666..3701039) 1 NC_011740.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3701039 hemN 7122538 hemN Escherichia fergusonii ATCC 35469 coproporphyrinogen III oxidase YP_002384685.1 3699666 R 585054 CDS YP_002384686.1 218550895 7122185 complement(3701228..3701797) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3701797 yihI 7122185 yihI Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384686.1 3701228 R 585054 CDS YP_002384687.1 218550896 7122824 3702355..3702951 1 NC_011740.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 3702951 engB 7122824 engB Escherichia fergusonii ATCC 35469 ribosome biogenesis GTP-binding protein YsxC YP_002384687.1 3702355 D 585054 CDS YP_002384688.1 218550897 7121808 complement(3703302..3706088) 1 NC_011740.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 3706088 polA 7121808 polA Escherichia fergusonii ATCC 35469 DNA polymerase I YP_002384688.1 3703302 R 585054 CDS YP_002384689.1 218550898 7120097 3706427..3707380 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; acyltransferase 3707380 yihG 7120097 yihG Escherichia fergusonii ATCC 35469 acyltransferase YP_002384689.1 3706427 D 585054 CDS YP_002384690.1 218550899 7123386 complement(3707425..3708843) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3708843 7123386 EFER_3615 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384690.1 3707425 R 585054 CDS YP_002384691.1 218550900 7120292 complement(3709008..3709634) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12498799, 93264419, 94016574, 94206930, 99298180, 10210188, 1429594, 1740115, 1934062, 8413591, 8494885, 8521518, 9194175, 9298646, 9300489, 9572841, 9600841, 9655827; Product type e : enzyme; protein disulfide isomerase I 3709634 dsbA 7120292 dsbA Escherichia fergusonii ATCC 35469 protein disulfide isomerase I YP_002384691.1 3709008 R 585054 CDS YP_002384692.1 218550901 7123555 complement(3709651..3710637) 1 NC_011740.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase 3710637 yihE 7123555 yihE Escherichia fergusonii ATCC 35469 serine/threonine protein kinase YP_002384692.1 3709651 R 585054 CDS YP_002384693.1 218550902 7123934 complement(3710714..3710983) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3710983 yihD 7123934 yihD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384693.1 3710714 R 585054 CDS YP_002384694.1 218550903 7121848 3711062..3711637 1 NC_011740.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA 3711637 mobA 7121848 mobA Escherichia fergusonii ATCC 35469 molybdopterin-guanine dinucleotide biosynthesis protein MobA YP_002384694.1 3711062 D 585054 CDS YP_002384695.1 218550904 7123247 3711634..3712146 1 NC_011740.1 in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway; molybdopterin-guanine dinucleotide biosynthesis protein MobB 3712146 mobB 7123247 mobB Escherichia fergusonii ATCC 35469 molybdopterin-guanine dinucleotide biosynthesis protein MobB YP_002384695.1 3711634 D 585054 CDS YP_002384696.1 218550905 7120385 complement(3717735..3718280) 1 NC_011740.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX; protoporphyrinogen oxidase 3718280 hemG 7120385 hemG Escherichia fergusonii ATCC 35469 protoporphyrinogen oxidase YP_002384696.1 3717735 R 585054 CDS YP_002384697.1 218550906 7122183 complement(3718292..3719743) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91100357, 2243799, 7896723; Product type t : transporter; potassium transporter 3719743 trkH 7122183 trkH Escherichia fergusonii ATCC 35469 potassium transporter YP_002384697.1 3718292 R 585054 CDS YP_002384698.1 218550907 7122158 complement(3719782..3720396) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15103642; Product type pf : factor; hypothetical protein 3720396 yigZ 7122158 yigZ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384698.1 3719782 R 585054 CDS YP_002384699.1 218550908 7121846 complement(3720396..3721727) 1 NC_011740.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters; proline dipeptidase 3721727 pepQ 7121846 pepQ Escherichia fergusonii ATCC 35469 proline dipeptidase YP_002384699.1 3720396 R 585054 CDS YP_002384700.1 218550909 7122578 3721917..3724106 1 NC_011740.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; multifunctional fatty acid oxidation complex subunit alpha 3724106 fadB 7122578 fadB Escherichia fergusonii ATCC 35469 multifunctional fatty acid oxidation complex subunit alpha YP_002384700.1 3721917 D 585054 CDS YP_002384701.1 218550910 7119986 3724116..3725279 1 NC_011740.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; 3-ketoacyl-CoA thiolase 3725279 fadA 7119986 fadA Escherichia fergusonii ATCC 35469 3-ketoacyl-CoA thiolase YP_002384701.1 3724116 D 585054 CDS YP_002384702.1 218550911 7119985 complement(3725463..3727298) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; arylsulfatase 3727298 7119985 EFER_3637 Escherichia fergusonii ATCC 35469 arylsulfatase YP_002384702.1 3725463 R 585054 CDS YP_002384703.1 218550912 7120293 complement(3727568..3728269) 1 NC_011740.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin; FMN reductase 3728269 fre 7120293 fre Escherichia fergusonii ATCC 35469 FMN reductase YP_002384703.1 3727568 R 585054 CDS YP_002384704.1 218550913 7123012 complement(3728315..3729808) 1 NC_011740.1 catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 3729808 ubiD 7123012 ubiD Escherichia fergusonii ATCC 35469 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_002384704.1 3728315 R 585054 CDS YP_002384705.1 218550914 7122618 3729975..3730463 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92011415, 92250420, 92261317, 1584020, 12007406; Product type r : regulator; transcriptional activator RfaH 3730463 rfaH 7122618 rfaH Escherichia fergusonii ATCC 35469 transcriptional activator RfaH YP_002384705.1 3729975 D 585054 CDS YP_002384706.1 218550915 7121387 complement(3730460..3731242) 1 NC_011740.1 magnesium dependent; not involved in the Sec-independent protein export system; DNase TatD 3731242 tatD 7121387 tatD Escherichia fergusonii ATCC 35469 DNase TatD YP_002384706.1 3730460 R 585054 CDS YP_002384707.1 218550916 7121977 complement(3731284..3732057) 1 NC_011740.1 with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane; twin-arginine protein translocation system subunit TatC 3732057 tatC 7121977 tatC Escherichia fergusonii ATCC 35469 twin-arginine protein translocation system subunit TatC YP_002384707.1 3731284 R 585054 CDS YP_002384708.1 218550917 7121976 complement(3732060..3732584) 1 NC_011740.1 mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 3732584 tatB 7121976 tatB Escherichia fergusonii ATCC 35469 sec-independent translocase YP_002384708.1 3732060 R 585054 CDS YP_002384709.1 218550918 7121975 complement(3732588..3732857) 1 NC_011740.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A 3732857 tatA 7121975 tatA Escherichia fergusonii ATCC 35469 twin arginine translocase protein A YP_002384709.1 3732588 R 585054 CDS YP_002384710.1 218550919 7121974 complement(3732936..3734576) 1 NC_011740.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; ubiquinone biosynthesis protein UbiB 3734576 ubiB 7121974 ubiB Escherichia fergusonii ATCC 35469 ubiquinone biosynthesis protein UbiB YP_002384710.1 3732936 R 585054 CDS YP_002384711.1 218550920 7122616 complement(3734573..3735178) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3735178 yigP 7122616 yigP Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384711.1 3734573 R 585054 CDS YP_002384712.1 218550921 7121845 complement(3735192..3735947) 1 NC_011740.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 3735947 ubiE 7121845 ubiE Escherichia fergusonii ATCC 35469 ubiquinone/menaquinone biosynthesis methyltransferase YP_002384712.1 3735192 R 585054 CDS YP_002384713.1 218550922 7122619 complement(3736042..3737469) 1 NC_011740.1 YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner; DNA recombination protein RmuC 3737469 rmuC 7122619 rmuC Escherichia fergusonii ATCC 35469 DNA recombination protein RmuC YP_002384713.1 3736042 R 585054 CDS YP_002384714.1 218550923 7121420 3737685..3738452 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator 3738452 7121420 EFER_3649 Escherichia fergusonii ATCC 35469 transcriptional regulator YP_002384714.1 3737685 D 585054 CDS YP_002384715.1 218550924 7120294 3738476..3739480 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; acidic carbohydrate kinase 3739480 7120294 EFER_3650 Escherichia fergusonii ATCC 35469 acidic carbohydrate kinase YP_002384715.1 3738476 D 585054 CDS YP_002384716.1 218550925 7123674 3739395..3740099 1 NC_011740.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase 3740099 7123674 EFER_3651 Escherichia fergusonii ATCC 35469 2-dehydro-3-deoxy-6-phosphogalactonate aldolase YP_002384716.1 3739395 D 585054 CDS YP_002384717.1 218550926 7120295 3740124..3741098 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; periplasmic binding protein 3741098 7120295 EFER_3652 Escherichia fergusonii ATCC 35469 periplasmic binding protein YP_002384717.1 3740124 D 585054 CDS YP_002384718.1 218550927 7120296 3741115..3741621 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; permease subunit 3741621 7120296 EFER_3653 Escherichia fergusonii ATCC 35469 permease subunit YP_002384718.1 3741115 D 585054 CDS YP_002384719.1 218550928 7123675 3741634..3743124 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3743124 7123675 EFER_3654 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384719.1 3741634 D 585054 CDS YP_002384720.1 218550929 7120297 complement(3743159..3743929) 1 NC_011740.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase 3743929 udp 7120297 udp Escherichia fergusonii ATCC 35469 uridine phosphorylase YP_002384720.1 3743159 R 585054 CDS YP_002384721.1 218550930 7122623 3744119..3744997 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12676709; Product type pe : enzyme; hydrolase 3744997 ysgA 7122623 ysgA Escherichia fergusonii ATCC 35469 hydrolase YP_002384721.1 3744119 D 585054 CDS YP_002384722.1 218550931 7119757 complement(3745084..3745848) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7805834; Product type pr : regulator; GntR family transcriptional regulator 3745848 7119757 EFER_3657 Escherichia fergusonii ATCC 35469 GntR family transcriptional regulator YP_002384722.1 3745084 R 585054 CDS YP_002384723.1 218550932 7123135 3745939..3746757 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hydrolase 3746757 7123135 EFER_3658 Escherichia fergusonii ATCC 35469 hydrolase YP_002384723.1 3745939 D 585054 CDS YP_002384724.1 218550933 7120298 3746930..3747805 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3747805 7120298 EFER_3659 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384724.1 3746930 D 585054 CDS YP_002384725.1 218550934 7120299 3747778..3748230 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3748230 7120299 EFER_3660 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384725.1 3747778 D 585054 CDS YP_002384726.1 218550935 7120300 complement(3748290..3748967) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; extracellular solute-binding protein 3748967 7120300 EFER_3661 Escherichia fergusonii ATCC 35469 extracellular solute-binding protein YP_002384726.1 3748290 R 585054 CDS YP_002384727.1 218550936 7120301 complement(3748970..3749938) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; HTH-type transcriptional regulator 3749938 7120301 EFER_3662 Escherichia fergusonii ATCC 35469 HTH-type transcriptional regulator YP_002384727.1 3748970 R 585054 CDS YP_002384728.1 218550937 7123136 3750409..3751467 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; lactonase 3751467 7123136 EFER_3663 Escherichia fergusonii ATCC 35469 lactonase YP_002384728.1 3750409 D 585054 CDS YP_002384729.1 218550938 7120302 3751479..3752744 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3752744 7120302 EFER_3664 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384729.1 3751479 D 585054 CDS YP_002384730.1 218550939 7120303 3752769..3754715 1 NC_011740.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 3754715 7120303 EFER_3665 Escherichia fergusonii ATCC 35469 aconitate hydratase YP_002384730.1 3752769 D 585054 CDS YP_002384731.1 218550940 7120304 3754760..3755929 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3755929 7120304 EFER_3666 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384731.1 3754760 D 585054 CDS YP_002384732.1 218550941 7120305 3755968..3758232 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3758232 7120305 EFER_3667 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384732.1 3755968 D 585054 CDS YP_002384733.1 218550942 7123137 3758247..3759410 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; Isocitrate dehydrogenase 3759410 7123137 EFER_3668 Escherichia fergusonii ATCC 35469 Isocitrate dehydrogenase YP_002384733.1 3758247 D 585054 CDS YP_002384734.1 218550943 7120306 3759467..3761989 1 NC_011740.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 3761989 7120306 EFER_3669 Escherichia fergusonii ATCC 35469 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase YP_002384734.1 3759467 D 585054 CDS YP_002384735.1 218550944 7120307 3762227..3763081 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; fumarylacetoacetate (FAA) hydrolase 3763081 7120307 EFER_3670 Escherichia fergusonii ATCC 35469 fumarylacetoacetate (FAA) hydrolase YP_002384735.1 3762227 D 585054 CDS YP_002384736.1 218550945 7120308 complement(3763116..3765377) 1 NC_011740.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase 3765377 metE 7120308 metE Escherichia fergusonii ATCC 35469 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase YP_002384736.1 3763116 R 585054 CDS YP_002384737.1 218550946 7120917 3765495..3766448 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90384950, 96303520, 2205852, 2643109; Product type r : regulator; DNA-binding transcriptional activator 3766448 metR 7120917 metR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional activator YP_002384737.1 3765495 D 585054 CDS YP_002384738.1 218550947 7120926 complement(3766336..3767235) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3767235 yigM 7120926 yigM Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384738.1 3766336 R 585054 CDS YP_002384739.1 218550948 7121844 complement(3767311..3768111) 1 NC_011740.1 purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium; sugar phosphatase 3768111 yigL 7121844 yigL Escherichia fergusonii ATCC 35469 sugar phosphatase YP_002384739.1 3767311 R 585054 CDS YP_002384740.1 218550949 7123385 complement(3768119..3769141) 1 NC_011740.1 lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates; lysophospholipase L2 3769141 pldB 7123385 pldB Escherichia fergusonii ATCC 35469 lysophospholipase L2 YP_002384740.1 3768119 R 585054 CDS YP_002384741.1 218550950 7123641 3769252..3769872 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99313167, 10386596; Product type t : transporter; homoserine/homoserine lactone efflux protein 3769872 rhtB 7123641 rhtB Escherichia fergusonii ATCC 35469 homoserine/homoserine lactone efflux protein YP_002384741.1 3769252 D 585054 CDS YP_002384742.1 218550951 7121403 3770031..3770891 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3770891 7121403 EFER_3677 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384742.1 3770031 D 585054 CDS YP_002384743.1 218550952 7120309 complement(3770928..3771548) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99313167, 10386596, 3027506; Product type t : transporter; threonine efflux system 3771548 rhtC 7120309 rhtC Escherichia fergusonii ATCC 35469 threonine efflux system YP_002384743.1 3770928 R 585054 CDS YP_002384744.1 218550953 7121404 complement(3771612..3773441) 1 NC_011740.1 functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; ATP-dependent DNA helicase RecQ 3773441 recQ 7121404 recQ Escherichia fergusonii ATCC 35469 ATP-dependent DNA helicase RecQ YP_002384744.1 3771612 R 585054 CDS YP_002384745.1 218550954 7123310 complement(3773511..3773993) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3773993 7123310 EFER_3680 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384745.1 3773511 R 585054 CDS YP_002384746.1 218550955 7123676 complement(3774042..3774911) 1 NC_011740.1 catalyzes the hydrolysis of phosphatidylcholine; phospholipase A 3774911 pldA 7123676 pldA Escherichia fergusonii ATCC 35469 phospholipase A YP_002384746.1 3774042 R 585054 CDS YP_002384747.1 218550956 7120087 3775075..3775542 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3775542 yigI 7120087 yigI Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384747.1 3775075 D 585054 CDS YP_002384748.1 218550957 7121843 3775594..3776484 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; chloramphenicol resistance permease 3776484 rarD 7121843 rarD Escherichia fergusonii ATCC 35469 chloramphenicol resistance permease YP_002384748.1 3775594 D 585054 CDS YP_002384749.1 218550958 7123466 complement(3776649..3776765) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3776765 7123466 EFER_3684 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384749.1 3776649 R 585054 CDS YP_002384750.1 218550959 7120310 3776974..3777354 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9868784; Product type pm : membrane component; hypothetical protein 3777354 yigF 7120310 yigF Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384750.1 3776974 D 585054 CDS YP_002384751.1 218550960 7121842 complement(3777397..3778347) 1 NC_011740.1 responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA 3778347 corA 7121842 corA Escherichia fergusonii ATCC 35469 magnesium/nickel/cobalt transporter CorA YP_002384751.1 3777397 R 585054 CDS YP_002384752.1 218550961 7122794 3778717..3779481 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3779481 yigE 7122794 yigE Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384752.1 3778717 D 585054 CDS YP_002384753.1 218550962 7121841 3779564..3780466 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3780466 7121841 EFER_3688 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384753.1 3779564 D 585054 CDS YP_002384754.1 218550963 7120311 complement(3780521..3782683) 1 NC_011740.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II 3782683 uvrD 7120311 uvrD Escherichia fergusonii ATCC 35469 DNA-dependent helicase II YP_002384754.1 3780521 R 585054 CDS YP_002384755.1 218550964 7122648 complement(3782767..3783483) 1 NC_011740.1 YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function; flavin mononucleotide phosphatase 3783483 yigB 7122648 yigB Escherichia fergusonii ATCC 35469 flavin mononucleotide phosphatase YP_002384755.1 3782767 R 585054 CDS YP_002384756.1 218550965 7121840 complement(3783483..3784379) 1 NC_011740.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 3784379 xerC 7121840 xerC Escherichia fergusonii ATCC 35469 site-specific tyrosine recombinase XerC YP_002384756.1 3783483 R 585054 CDS YP_002384757.1 218550966 7122384 complement(3784376..3785083) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3785083 yigA 7122384 yigA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384757.1 3784376 R 585054 CDS YP_002384758.1 218550967 7123384 complement(3785080..3785904) 1 NC_011740.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 3785904 dapF 7123384 dapF Escherichia fergusonii ATCC 35469 diaminopimelate epimerase YP_002384758.1 3785080 R 585054 CDS YP_002384759.1 218550968 7122868 complement(3785941..3786144) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; lipoprotein 3786144 yifL 7122868 yifL Escherichia fergusonii ATCC 35469 lipoprotein YP_002384759.1 3785941 R 585054 CDS YP_002384760.1 218550969 7121839 3786303..3787811 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3787811 7121839 EFER_3695 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384760.1 3786303 D 585054 CDS YP_002384761.1 218550970 7123677 3787808..3789121 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3789121 7123677 EFER_3696 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384761.1 3787808 D 585054 CDS YP_002384762.1 218550971 7123678 3789184..3789504 1 NC_011740.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein 3789504 cyaY 7123678 cyaY Escherichia fergusonii ATCC 35469 frataxin-like protein YP_002384762.1 3789184 D 585054 CDS YP_002384763.1 218550972 7123540 complement(3789544..3792090) 1 NC_011740.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase 3792090 cyaA 7123540 cyaA Escherichia fergusonii ATCC 35469 adenylate cyclase YP_002384763.1 3789544 R 585054 CDS YP_002384764.1 218550973 7122836 3792455..3793396 1 NC_011740.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 3793396 hemC 7122836 hemC Escherichia fergusonii ATCC 35469 porphobilinogen deaminase YP_002384764.1 3792455 D 585054 CDS YP_002384765.1 218550974 7123728 3793393..3794133 1 NC_011740.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase 3794133 hemD 7123728 hemD Escherichia fergusonii ATCC 35469 uroporphyrinogen-III synthase YP_002384765.1 3793393 D 585054 CDS YP_002384766.1 218550975 7123573 3794155..3795330 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 89098348, 92358234, 3054815, 3062586, 9298646; Product type pe : enzyme; uroporphyrinogen III C-methyltransferase 3795330 hemX 7123573 hemX Escherichia fergusonii ATCC 35469 uroporphyrinogen III C-methyltransferase YP_002384766.1 3794155 D 585054 CDS YP_002384767.1 218550976 7122186 3795333..3796529 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 89041586; Product type pe : enzyme; protoheme IX biogenesis protein 3796529 hemY 7122186 hemY Escherichia fergusonii ATCC 35469 protoheme IX biogenesis protein YP_002384767.1 3795333 D 585054 CDS YP_002384768.1 218550977 7123996 3796322..3797167 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3797167 7123996 EFER_3704 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384768.1 3796322 D 585054 CDS YP_002384769.1 218550978 7121184 3797815..3799470 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16766528, 92358234, 15477040; Product type e : enzyme; arylsulfatase-like protein 3799470 aslA 7121184 aslA Escherichia fergusonii ATCC 35469 arylsulfatase-like protein YP_002384769.1 3797815 D 585054 CDS YP_002384770.1 218550979 7120564 complement(3799561..3800796) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11222759, 2180918, 12419807, 14749327; Product type pr : regulator; regulator of arylsulfatase activity 3800796 aslB 7120564 aslB Escherichia fergusonii ATCC 35469 regulator of arylsulfatase activity YP_002384770.1 3799561 R 585054 CDS YP_002384771.1 218550980 7123095 complement(3801483..3802868) 1 NC_011740.1 uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function; transporter 3802868 yifK 7123095 yifK Escherichia fergusonii ATCC 35469 transporter YP_002384771.1 3801483 R 585054 CDS YP_002384772.1 218550981 7123933 complement(3803059..3803799) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88086874, 90337949, 92112804; Product type e : enzyme; UDP-N-acetyl-D-mannosaminuronic acid transferase 3803799 rffM 7123933 rffM Escherichia fergusonii ATCC 35469 UDP-N-acetyl-D-mannosaminuronic acid transferase YP_002384772.1 3803059 R 585054 CDS YP_002384773.1 218550982 7123860 complement(3803802..3805154) 1 NC_011740.1 enterobacterial common antigen polymerase; common antigen polymerase 3805154 wzyE 7123860 wzyE Escherichia fergusonii ATCC 35469 common antigen polymerase YP_002384773.1 3803802 R 585054 CDS YP_002384774.1 218550983 7122378 complement(3805151..3806230) 1 NC_011740.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis; 4-alpha-L-fucosyltransferase 3806230 rffT 7122378 rffT Escherichia fergusonii ATCC 35469 4-alpha-L-fucosyltransferase YP_002384774.1 3805151 R 585054 CDS YP_002384775.1 218550984 7121395 complement(3806227..3807477) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12621029, 20044778; Product type t : transporter; O-antigen translocase 3807477 wzxE 7121395 wzxE Escherichia fergusonii ATCC 35469 O-antigen translocase YP_002384775.1 3806227 R 585054 CDS YP_002384776.1 218550985 7122377 complement(3807479..3808609) 1 NC_011740.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase 3808609 rffA 7122377 rffA Escherichia fergusonii ATCC 35469 TDP-4-oxo-6-deoxy-D-glucose transaminase YP_002384776.1 3807479 R 585054 CDS YP_002384777.1 218550986 7123312 complement(3808614..3809288) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90212314, 90337949, 92112804, 8366065; Product type e : enzyme; TDP-fucosamine acetyltransferase 3809288 rffC 7123312 rffC Escherichia fergusonii ATCC 35469 TDP-fucosamine acetyltransferase YP_002384777.1 3808614 R 585054 CDS YP_002384778.1 218550987 7121391 complement(3809266..3810147) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94292435, 96032389; Product type e : enzyme; glucose-1-phosphate thymidylyltransferase 3810147 rffH 7121391 rffH Escherichia fergusonii ATCC 35469 glucose-1-phosphate thymidylyltransferase YP_002384778.1 3809266 R 585054 CDS YP_002384779.1 218550988 7123313 complement(3810166..3811233) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88086930, 90212314, 90337949, 92112804, 92174908, 94018634, 94042873, 7559340; Product type e : enzyme; dTDP-glucose 4,6-dehydratase 3811233 rffG 7123313 rffG Escherichia fergusonii ATCC 35469 dTDP-glucose 4,6-dehydratase YP_002384779.1 3810166 R 585054 CDS YP_002384780.1 218550989 7121394 complement(3811233..3812495) 1 NC_011740.1 catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; UDP-N-acetyl-D-mannosamine dehydrogenase 3812495 wecC 7121394 wecC Escherichia fergusonii ATCC 35469 UDP-N-acetyl-D-mannosamine dehydrogenase YP_002384780.1 3811233 R 585054 CDS YP_002384781.1 218550990 7121392 complement(3812492..3813622) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90212314, 90337949, 92112804, 94042873, 11106477, 7559340, 8170390, 8226648; Product type e : enzyme; UDP-N-acetyl glucosamine-2-epimerase 3813622 rffE 7121392 rffE Escherichia fergusonii ATCC 35469 UDP-N-acetyl glucosamine-2-epimerase YP_002384781.1 3812492 R 585054 CDS YP_002384782.1 218550991 7121393 complement(3813678..3814724) 1 NC_011740.1 Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein; lipopolysaccharide biosynthesis protein WzzE 3814724 wzzE 7121393 wzzE Escherichia fergusonii ATCC 35469 lipopolysaccharide biosynthesis protein WzzE YP_002384782.1 3813678 R 585054 CDS YP_002384783.1 218550992 7122379 complement(3814736..3815839) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92114763, 94245613, 94292435, 10629198, 11024259, 11700352, 11832520, 1722555, 1730666; Product type e : enzyme; UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase 3815839 rfe 7122379 rfe Escherichia fergusonii ATCC 35469 UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase YP_002384783.1 3814736 R 585054 CDS YP_002384784.1 218550993 7121390 complement(3816067..3817326) 1 NC_011740.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 3817326 rho 7121390 rho Escherichia fergusonii ATCC 35469 transcription termination factor Rho YP_002384784.1 3816067 R 585054 CDS YP_002384785.1 218550994 7121401 complement(3817651..3817980) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90202710, 91154193, 92250497, 99175138, 10489448, 1094461, 10947986, 1561103, 2181145, 2193685, 3891733, 4616096, 4883076, 6098320, 6099324, 7812718, 8098620, 8253691; Product type c : carrier; thioredoxin 3817980 trxA 7121401 trxA Escherichia fergusonii ATCC 35469 thioredoxin YP_002384785.1 3817651 R 585054 CDS YP_002384786.1 218550995 7123438 3818111..3819376 1 NC_011740.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB 3819376 rhlB 7123438 rhlB Escherichia fergusonii ATCC 35469 ATP-dependent RNA helicase RhlB YP_002384786.1 3818111 D 585054 CDS YP_002384787.1 218550996 7121400 3819512..3820996 1 NC_011740.1 catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation; guanosine pentaphosphate phosphohydrolase 3820996 gpp 7121400 gpp Escherichia fergusonii ATCC 35469 guanosine pentaphosphate phosphohydrolase YP_002384787.1 3819512 D 585054 CDS YP_002384788.1 218550997 7120611 complement(3821044..3823065) 1 NC_011740.1 single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication; ATP-dependent DNA helicase Rep 3823065 rep 7120611 rep Escherichia fergusonii ATCC 35469 ATP-dependent DNA helicase Rep YP_002384788.1 3821044 R 585054 CDS YP_002384789.1 218550998 7121386 3823152..3823433 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94215709, 7878732, 7925971, 8163020; Product type e : enzyme; peptidyl-prolyl cis-trans isomerase C 3823433 ppiC 7121386 ppiC Escherichia fergusonii ATCC 35469 peptidyl-prolyl cis-trans isomerase C YP_002384789.1 3823152 D 585054 CDS YP_002384790.1 218550999 7123107 complement(3823479..3824954) 1 NC_011740.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 3824954 ilvC 7123107 ilvC Escherichia fergusonii ATCC 35469 ketol-acid reductoisomerase YP_002384790.1 3823479 R 585054 CDS YP_002384791.1 218551000 7120728 3825020..3825994 1 NC_011740.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY 3825994 ilvY 7120728 ilvY Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator IlvY YP_002384791.1 3825020 D 585054 CDS YP_002384792.1 218551001 7123211 complement(3825991..3827535) 1 NC_011740.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase 3827535 ilvA 7123211 ilvA Escherichia fergusonii ATCC 35469 threonine dehydratase YP_002384792.1 3825991 R 585054 CDS YP_002384793.1 218551002 7120726 complement(3827538..3829388) 1 NC_011740.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 3829388 ilvD 7120726 ilvD Escherichia fergusonii ATCC 35469 dihydroxy-acid dehydratase YP_002384793.1 3827538 R 585054 CDS YP_002384794.1 218551003 7120729 complement(3829453..3830382) 1 NC_011740.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 3830382 ilvE 7120729 ilvE Escherichia fergusonii ATCC 35469 branched-chain amino acid aminotransferase YP_002384794.1 3829453 R 585054 CDS YP_002384795.1 218551004 7120730 complement(3830402..3830665) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92332418, 92380929, 1569580, 3550695, 3897211; Product type e : enzyme; acetolactate synthase 2 regulatory subunit 3830665 ilvM 7120730 ilvM Escherichia fergusonii ATCC 35469 acetolactate synthase 2 regulatory subunit YP_002384795.1 3830402 R 585054 CDS YP_002384796.1 218551005 7120734 complement(3830662..3832308) 1 NC_011740.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase 2 catalytic subunit 3832308 ilvG 7120734 ilvG Escherichia fergusonii ATCC 35469 acetolactate synthase 2 catalytic subunit YP_002384796.1 3830662 R 585054 CDS YP_002384797.1 218551006 7120731 complement(3832449..3832547) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87174741; Product type l : leader peptide; ilvG operon leader peptide 3832547 ilvL 7120731 ilvL Escherichia fergusonii ATCC 35469 ilvG operon leader peptide YP_002384797.1 3832449 R 585054 CDS YP_002384798.1 218551007 7120733 3832870..3834420 1 NC_011740.1 among the AAA+ ATPases, the YifB protease family belongs to the Helix 2 insert clade; unknown function; ATP-dependent protease 3834420 yifB 7120733 yifB Escherichia fergusonii ATCC 35469 ATP-dependent protease YP_002384798.1 3832870 D 585054 CDS YP_002384799.1 218551008 7121838 complement(3834445..3834783) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3834783 yifE 7121838 yifE Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384799.1 3834445 R 585054 CDS YP_002384800.1 218551009 7123932 3834902..3835741 1 NC_011740.1 Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon; transcriptional regulator HdfR 3835741 hdfR 7123932 hdfR Escherichia fergusonii ATCC 35469 transcriptional regulator HdfR YP_002384800.1 3834902 D 585054 CDS YP_002384801.1 218551010 7120384 3841685..3843274 1 NC_011740.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 3843274 purH 7120384 purH Escherichia fergusonii ATCC 35469 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_002384801.1 3841685 D 585054 CDS YP_002384802.1 218551011 7124022 3843286..3844575 1 NC_011740.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 3844575 purD 7124022 purD Escherichia fergusonii ATCC 35469 phosphoribosylamine--glycine ligase YP_002384802.1 3843286 D 585054 CDS YP_002384803.1 218551012 7122320 complement(3844572..3845897) 1 NC_011740.1 DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein; transcriptional regulatory protein ZraR 3845897 zraR 7122320 zraR Escherichia fergusonii ATCC 35469 transcriptional regulatory protein ZraR YP_002384803.1 3844572 R 585054 CDS YP_002384804.1 218551013 7121814 complement(3845894..3847270) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21140164, 89327164, 92255260, 11243806, 2666400; Product type r : regulator; sensor protein ZraS 3847270 zraS 7121814 zraS Escherichia fergusonii ATCC 35469 sensor protein ZraS YP_002384804.1 3845894 R 585054 CDS YP_002384805.1 218551014 7123420 3847508..3847933 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98362023, 9694902; Product type pf : factor; zinc resistance protein 3847933 zraP 7123420 zraP Escherichia fergusonii ATCC 35469 zinc resistance protein YP_002384805.1 3847508 D 585054 CDS YP_002384806.1 218551015 7122667 complement(3847935..3848630) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3848630 yjaH 7122667 yjaH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384806.1 3847935 R 585054 CDS YP_002384807.1 218551016 7123937 complement(3848643..3848915) 1 NC_011740.1 histone-like DNA-binding protein; transcriptional regulator HU subunit alpha 3848915 hupA 7123937 hupA Escherichia fergusonii ATCC 35469 transcriptional regulator HU subunit alpha YP_002384807.1 3848643 R 585054 CDS YP_002384808.1 218551017 7122234 complement(3849102..3849692) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3849692 yjaG 7122234 yjaG Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384808.1 3849102 R 585054 CDS YP_002384809.1 218551018 7121864 complement(3849735..3850406) 1 NC_011740.1 Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures; endonuclease V 3850406 nfi 7121864 nfi Escherichia fergusonii ATCC 35469 endonuclease V YP_002384809.1 3849735 R 585054 CDS YP_002384810.1 218551019 7120685 complement(3850416..3851480) 1 NC_011740.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 3851480 hemE 7120685 hemE Escherichia fergusonii ATCC 35469 uroporphyrinogen decarboxylase YP_002384810.1 3850416 R 585054 CDS YP_002384811.1 218551020 7122181 complement(3851520..3852293) 1 NC_011740.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase 3852293 nudC 7122181 nudC Escherichia fergusonii ATCC 35469 NADH pyrophosphatase YP_002384811.1 3851520 R 585054 CDS YP_002384812.1 218551021 7119668 3852388..3852864 1 NC_011740.1 binds specifically to the major sigma factor sigma 70; active in stationary phase; anti-RNA polymerase sigma 70 factor 3852864 rsd 7119668 rsd Escherichia fergusonii ATCC 35469 anti-RNA polymerase sigma 70 factor YP_002384812.1 3852388 D 585054 CDS YP_002384813.1 218551022 7121144 3853097..3854992 1 NC_011740.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 3854992 thiC 7121144 thiC Escherichia fergusonii ATCC 35469 thiamine biosynthesis protein ThiC YP_002384813.1 3853097 D 585054 CDS YP_002384814.1 218551023 7121990 3854992..3855627 1 NC_011740.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate; thiamine-phosphate pyrophosphorylase 3855627 thiE 7121990 thiE Escherichia fergusonii ATCC 35469 thiamine-phosphate pyrophosphorylase YP_002384814.1 3854992 D 585054 CDS YP_002384815.1 218551024 7121992 3855620..3856375 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8432721, 94089392, 98298179, 10082377, 9632726; Product type e : enzyme; thiamin (thiazole moiety) biosynthesis protein 3856375 thiF 7121992 thiF Escherichia fergusonii ATCC 35469 thiamin (thiazole moiety) biosynthesis protein YP_002384815.1 3855620 D 585054 CDS YP_002384816.1 218551025 7121993 3856359..3856559 1 NC_011740.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; sulfur carrier protein ThiS 3856559 thiS 7121993 thiS Escherichia fergusonii ATCC 35469 sulfur carrier protein ThiS YP_002384816.1 3856359 D 585054 CDS YP_002384817.1 218551026 7121999 3856561..3857331 1 NC_011740.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 3857331 thiG 7121999 thiG Escherichia fergusonii ATCC 35469 thiazole synthase YP_002384817.1 3856561 D 585054 CDS YP_002384818.1 218551027 7123408 3857328..3858461 1 NC_011740.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; thiamine biosynthesis protein ThiH 3858461 thiH 7123408 thiH Escherichia fergusonii ATCC 35469 thiamine biosynthesis protein ThiH YP_002384818.1 3857328 D 585054 CDS YP_002384819.1 218551028 7123960 complement(3858703..3862926) 1 NC_011740.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 3862926 rpoC 7123960 rpoC Escherichia fergusonii ATCC 35469 DNA-directed RNA polymerase subunit beta' YP_002384819.1 3858703 R 585054 CDS YP_002384820.1 218551029 7121121 complement(3863003..3867031) 1 NC_011740.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 3867031 rpoB 7121121 rpoB Escherichia fergusonii ATCC 35469 DNA-directed RNA polymerase subunit beta YP_002384820.1 3863003 R 585054 CDS YP_002384821.1 218551030 7121120 complement(3867351..3867716) 1 NC_011740.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 3867716 rplL 7121120 rplL Escherichia fergusonii ATCC 35469 50S ribosomal protein L7/L12 YP_002384821.1 3867351 R 585054 CDS YP_002384822.1 218551031 7121102 complement(3867783..3868280) 1 NC_011740.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 3868280 rplJ 7121102 rplJ Escherichia fergusonii ATCC 35469 50S ribosomal protein L10 YP_002384822.1 3867783 R 585054 CDS YP_002384823.1 218551032 7121100 complement(3868693..3869397) 1 NC_011740.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 3869397 rplA 7121100 rplA Escherichia fergusonii ATCC 35469 50S ribosomal protein L1 YP_002384823.1 3868693 R 585054 CDS YP_002384824.1 218551033 7121438 complement(3869401..3869829) 1 NC_011740.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 3869829 rplK 7121438 rplK Escherichia fergusonii ATCC 35469 50S ribosomal protein L11 YP_002384824.1 3869401 R 585054 CDS YP_002384825.1 218551034 7121101 complement(3869988..3870533) 1 NC_011740.1 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 3870533 nusG 7121101 nusG Escherichia fergusonii ATCC 35469 transcription antitermination protein NusG YP_002384825.1 3869988 R 585054 CDS YP_002384826.1 218551035 7119686 complement(3870535..3870918) 1 NC_011740.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 3870918 secE 7119686 secE Escherichia fergusonii ATCC 35469 preprotein translocase subunit SecE YP_002384826.1 3870535 R 585054 CDS YP_002384827.1 218551036 7121762 complement(3871148..3872332) 1 NC_011740.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 3872332 tufB 7121762 tufB Escherichia fergusonii ATCC 35469 elongation factor Tu YP_002384827.1 3871148 R 585054 CDS YP_002384828.1 218551037 7120053 3873250..3874200 1 NC_011740.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 3874200 coaA 7120053 coaA Escherichia fergusonii ATCC 35469 pantothenate kinase YP_002384828.1 3873250 D 585054 CDS YP_002384829.1 218551038 7120908 complement(3874229..3875194) 1 NC_011740.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 3875194 birA 7120908 birA Escherichia fergusonii ATCC 35469 biotin--protein ligase YP_002384829.1 3874229 R 585054 CDS YP_002384830.1 218551039 7121672 complement(3875191..3876219) 1 NC_011740.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 3876219 murB 7121672 murB Escherichia fergusonii ATCC 35469 UDP-N-acetylenolpyruvoylglucosamine reductase YP_002384830.1 3875191 R 585054 CDS YP_002384831.1 218551040 7120383 complement(3881746..3882603) 1 NC_011740.1 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 3882603 murI 7120383 murI Escherichia fergusonii ATCC 35469 glutamate racemase YP_002384831.1 3881746 R 585054 CDS YP_002384832.2 229598031 7120649 complement(3882548..3884392) 1 NC_011740.1 involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space; vitamin B12/cobalamin outer membrane transporter 3884392 btuB 7120649 btuB Escherichia fergusonii ATCC 35469 vitamin B12/cobalamin outer membrane transporter YP_002384832.2 3882548 R 585054 CDS YP_002384833.1 218551042 7121680 3884761..3885861 1 NC_011740.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase 3885861 trmA 7121680 trmA Escherichia fergusonii ATCC 35469 tRNA (uracil-5-)-methyltransferase YP_002384833.1 3884761 D 585054 CDS YP_002384834.1 218551043 7122159 complement(3885901..3886260) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3886260 yijD 7122159 yijD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384834.1 3885901 R 585054 CDS YP_002384835.1 218551044 7121859 complement(3886260..3886910) 1 NC_011740.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR 3886910 fabR 7121859 fabR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional repressor FabR YP_002384835.1 3886260 R 585054 CDS YP_002384836.1 218551045 7123624 complement(3887014..3888330) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; proton/ carboxylic acid permease 3888330 7123624 EFER_3798 Escherichia fergusonii ATCC 35469 proton/ carboxylic acid permease YP_002384836.1 3887014 R 585054 CDS YP_002384837.1 218551046 7120313 complement(3888374..3889540) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7730270; Product type e : enzyme; Hippurate hydrolase 3889540 7120313 EFER_3799 Escherichia fergusonii ATCC 35469 Hippurate hydrolase YP_002384837.1 3888374 R 585054 CDS YP_002384838.1 218551047 7123679 3889870..3891270 1 NC_011740.1 catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase 3891270 sthA 7123679 sthA Escherichia fergusonii ATCC 35469 soluble pyridine nucleotide transhydrogenase YP_002384838.1 3889870 D 585054 CDS YP_002384839.1 218551048 7121951 complement(3891253..3892170) 1 NC_011740.1 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR 3892170 oxyR 7121951 oxyR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator OxyR YP_002384839.1 3891253 R 585054 CDS YP_002384840.1 218551049 7119707 complement(3892437..3893810) 1 NC_011740.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 3893810 argH 7119707 argH Escherichia fergusonii ATCC 35469 argininosuccinate lyase YP_002384840.1 3892437 R 585054 CDS YP_002384841.1 218551050 7123178 complement(3893871..3894644) 1 NC_011740.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 3894644 argB 7123178 argB Escherichia fergusonii ATCC 35469 acetylglutamate kinase YP_002384841.1 3893871 R 585054 CDS YP_002384842.1 218551051 7120537 complement(3894655..3895659) 1 NC_011740.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 3895659 argC 7120537 argC Escherichia fergusonii ATCC 35469 N-acetyl-gamma-glutamyl-phosphate reductase YP_002384842.1 3894655 R 585054 CDS YP_002384843.1 218551052 7120538 3895813..3896964 1 NC_011740.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase 3896964 argE 7120538 argE Escherichia fergusonii ATCC 35469 acetylornithine deacetylase YP_002384843.1 3895813 D 585054 CDS YP_002384844.1 218551053 7120539 3897310..3899961 1 NC_011740.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 3899961 ppc 7120539 ppc Escherichia fergusonii ATCC 35469 phosphoenolpyruvate carboxylase YP_002384844.1 3897310 D 585054 CDS YP_002384845.1 218551054 7120107 3900158..3901891 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10456927; Product type pm : membrane component; hypothetical protein 3901891 yijP 7120107 yijP Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384845.1 3900158 D 585054 CDS YP_002384846.1 218551055 7121862 3902121..3902972 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator 3902972 yijO 7121862 yijO Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YP_002384846.1 3902121 D 585054 CDS YP_002384847.1 218551056 7123388 complement(3902959..3903300) 1 NC_011740.1 FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog; fructose-like phosphotransferase EIIB subunit 3 3903300 frwD 7123388 frwD Escherichia fergusonii ATCC 35469 fructose-like phosphotransferase EIIB subunit 3 YP_002384847.1 3902959 R 585054 CDS YP_002384848.1 218551057 7123023 complement(3903302..3904180) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95291446, 14673546, 7773398; Product type e : enzyme; pyruvate formate lyase II activase 3904180 pflC 7123023 pflC Escherichia fergusonii ATCC 35469 pyruvate formate lyase II activase YP_002384848.1 3903302 R 585054 CDS YP_002384849.1 218551058 7122584 complement(3904146..3906443) 1 NC_011740.1 involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein; formate acetyltransferase 2 3906443 pflD 7122584 pflD Escherichia fergusonii ATCC 35469 formate acetyltransferase 2 YP_002384849.1 3904146 R 585054 CDS YP_002384850.1 218551059 7122585 complement(3906494..3906814) 1 NC_011740.1 FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS; PTS system fructose-like transporter subunit IIB 3906814 frwB 7122585 frwB Escherichia fergusonii ATCC 35469 PTS system fructose-like transporter subunit IIB YP_002384850.1 3906494 R 585054 CDS YP_002384851.1 218551060 7123021 complement(3906825..3907904) 1 NC_011740.1 FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site; fructose-like permease EIIC subunit 2 3907904 frwC 7123021 frwC Escherichia fergusonii ATCC 35469 fructose-like permease EIIC subunit 2 YP_002384851.1 3906825 R 585054 CDS YP_002384852.1 218551061 7123022 3908213..3910714 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 95291446, 7773398; Product type t : transporter; PTS system transporter protein Hpr /enzyme I /subunit IIA 3910714 ptsA 7123022 ptsA Escherichia fergusonii ATCC 35469 PTS system transporter protein Hpr /enzyme I /subunit IIA YP_002384852.1 3908213 D 585054 CDS YP_002384853.1 218551062 7122314 3910726..3911388 1 NC_011740.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 3911388 fsaB 7122314 fsaB Escherichia fergusonii ATCC 35469 fructose-6-phosphate aldolase YP_002384853.1 3910726 D 585054 CDS YP_002384854.1 218551063 7123024 3911399..3912502 1 NC_011740.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 3912502 gldA 7123024 gldA Escherichia fergusonii ATCC 35469 glycerol dehydrogenase YP_002384854.1 3911399 D 585054 CDS YP_002384855.1 218551064 7120184 3912621..3913238 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3913238 yijF 7120184 yijF Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384855.1 3912621 D 585054 CDS YP_002384856.1 218551065 7121861 complement(3913263..3914168) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; permease 3914168 yijE 7121861 yijE Escherichia fergusonii ATCC 35469 permease YP_002384856.1 3913263 R 585054 CDS YP_002384857.1 218551066 7121860 complement(3914262..3916442) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90292022, 94209230, 3045098; Product type e : enzyme; catalase/hydroperoxidase HPI(I) 3916442 katG 7121860 katG Escherichia fergusonii ATCC 35469 catalase/hydroperoxidase HPI(I) YP_002384857.1 3914262 R 585054 CDS YP_002384858.1 218551067 7120800 complement(3916770..3917660) 1 NC_011740.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 3917660 metF 7120800 metF Escherichia fergusonii ATCC 35469 5,10-methylenetetrahydrofolate reductase YP_002384858.1 3916770 R 585054 CDS YP_002384859.1 218551068 7120918 3918010..3918984 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3918984 7120918 EFER_3822 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384859.1 3918010 D 585054 CDS YP_002384860.1 218551069 7120314 3919036..3920547 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; GntR family transcriptional regulator 3920547 7120314 EFER_3823 Escherichia fergusonii ATCC 35469 GntR family transcriptional regulator YP_002384860.1 3919036 D 585054 CDS YP_002384861.1 218551070 7123138 complement(3920492..3921658) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; Alanine racemase 3 3921658 7123138 EFER_3824 Escherichia fergusonii ATCC 35469 Alanine racemase 3 YP_002384861.1 3920492 R 585054 CDS YP_002384862.1 218551071 7120315 complement(3921598..3922899) 1 NC_011740.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 3922899 glyAB 7120315 glyAB Escherichia fergusonii ATCC 35469 serine hydroxymethyltransferase YP_002384862.1 3921598 R 585054 CDS YP_002384863.1 218551072 7120317 3923910..3924284 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; decarboxylase 3924284 7120317 EFER_3828 Escherichia fergusonii ATCC 35469 decarboxylase YP_002384863.1 3923910 D 585054 CDS YP_002384864.1 218551073 7120318 complement(3924364..3925917) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; phosphoesterase 3925917 7120318 EFER_3829 Escherichia fergusonii ATCC 35469 phosphoesterase YP_002384864.1 3924364 R 585054 CDS YP_002384865.1 218551074 7123139 3926050..3927180 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3927180 7123139 EFER_3830 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384865.1 3926050 D 585054 CDS YP_002384866.1 218551075 7120319 complement(3927144..3929576) 1 NC_011740.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartate kinase II/homoserine dehydrogenase II 3929576 metL 7120319 metL Escherichia fergusonii ATCC 35469 bifunctional aspartate kinase II/homoserine dehydrogenase II YP_002384866.1 3927144 R 585054 CDS YP_002384867.1 218551076 7120923 complement(3929579..3930739) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87326410, 90148970, 3307782, 6361020, 9843488; Product type e : enzyme; cystathionine gamma-synthase, PLP-dependent 3930739 metB 7120923 metB Escherichia fergusonii ATCC 35469 cystathionine gamma-synthase, PLP-dependent YP_002384867.1 3929579 R 585054 CDS YP_002384868.1 218551077 7120915 3931016..3931333 1 NC_011740.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ 3931333 metJ 7120915 metJ Escherichia fergusonii ATCC 35469 transcriptional repressor protein MetJ YP_002384868.1 3931016 D 585054 CDS YP_002384869.1 218551078 7123776 3931393..3932001 1 NC_011740.1 member of the NlpC/P60 superfamily of peptidases; peptidoglycan peptidase 3932001 yiiX 7123776 yiiX Escherichia fergusonii ATCC 35469 peptidoglycan peptidase YP_002384869.1 3931393 D 585054 CDS YP_002384870.1 218551079 7121858 3932005..3932631 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3932631 7121858 EFER_3835 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384870.1 3932005 D 585054 CDS YP_002384871.1 218551080 7120320 complement(3932686..3932898) 1 NC_011740.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 3932898 rpmE 7120320 rpmE Escherichia fergusonii ATCC 35469 50S ribosomal protein L31 YP_002384871.1 3932686 R 585054 CDS YP_002384872.1 218551081 7121116 3933101..3935299 1 NC_011740.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 3935299 priA 7121116 priA Escherichia fergusonii ATCC 35469 primosome assembly protein PriA YP_002384872.1 3933101 D 585054 CDS YP_002384873.1 218551082 7120125 3935455..3936480 1 NC_011740.1 negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins; DNA-binding transcriptional regulator CytR 3936480 cytR 7120125 cytR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator CytR YP_002384873.1 3935455 D 585054 CDS YP_002384874.1 218551083 7122859 3936574..3937518 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9282742, 93285993, 8509333; Product type cp : cell process; cell division protein FtsN 3937518 ftsN 7122859 ftsN Escherichia fergusonii ATCC 35469 cell division protein FtsN YP_002384874.1 3936574 D 585054 CDS YP_002384875.1 218551084 7120150 3937611..3938141 1 NC_011740.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 3938141 hslV 7120150 hslV Escherichia fergusonii ATCC 35469 ATP-dependent protease peptidase subunit YP_002384875.1 3937611 D 585054 CDS YP_002384876.1 218551085 7122230 3938151..3939482 1 NC_011740.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 3939482 hslU 7122230 hslU Escherichia fergusonii ATCC 35469 ATP-dependent protease ATP-binding subunit HslU YP_002384876.1 3938151 D 585054 CDS YP_002384877.1 218551086 7122229 3939549..3940475 1 NC_011740.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 3940475 menA 7122229 menA Escherichia fergusonii ATCC 35469 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_002384877.1 3939549 D 585054 CDS YP_002384878.1 218551087 7121256 3940568..3941053 1 NC_011740.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA 3941053 rraA 7121256 rraA Escherichia fergusonii ATCC 35469 ribonuclease activity regulator protein RraA YP_002384878.1 3940568 D 585054 CDS YP_002384879.1 218551088 7121141 complement(3941115..3941360) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3941360 yiiU 7121141 yiiU Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384879.1 3941115 R 585054 CDS YP_002384880.1 218551089 7123387 complement(3941450..3941608) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3941608 7123387 EFER_3845 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384880.1 3941450 R 585054 CDS YP_002384881.1 218551090 7120321 3941788..3942633 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12629974, 12948772, 14646142, 15004242, 90094250, 92210584, 11039922, 11101882, 11226336, 11964478, 1372899, 2544860, 6998951; Product type t : transporter; glycerol facilitator 3942633 glpF 7120321 glpF Escherichia fergusonii ATCC 35469 glycerol facilitator YP_002384881.1 3941788 D 585054 CDS YP_002384882.1 218551091 7120577 3942656..3944164 1 NC_011740.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 3944164 glpK 7120577 glpK Escherichia fergusonii ATCC 35469 glycerol kinase YP_002384882.1 3942656 D 585054 CDS YP_002384883.1 218551092 7123720 3944277..3945287 1 NC_011740.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 3945287 glpX 7123720 glpX Escherichia fergusonii ATCC 35469 fructose 1,6-bisphosphatase II YP_002384883.1 3944277 D 585054 CDS YP_002384884.1 218551093 7120581 3945384..3946130 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93194782, 94092163, 95050480, 95362685, 1400248, 2834327, 7961651, 8449868, 9149148; Product type e : enzyme; ferredoxin-NADP reductase 3946130 fpr 7120581 fpr Escherichia fergusonii ATCC 35469 ferredoxin-NADP reductase YP_002384884.1 3945384 D 585054 CDS YP_002384885.1 218551094 7123008 complement(3946135..3946563) 1 NC_011740.1 with UspC and Usp E is involved in resistance to UV radiation; universal stress protein UspD 3946563 yiiT 7123008 yiiT Escherichia fergusonii ATCC 35469 universal stress protein UspD YP_002384885.1 3946135 R 585054 CDS YP_002384886.1 218551095 7121857 complement(3946591..3946965) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3946965 7121857 EFER_3851 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384886.1 3946591 R 585054 CDS YP_002384887.1 218551096 7120322 complement(3947099..3947539) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3947539 yiiR 7120322 yiiR Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384887.1 3947099 R 585054 CDS YP_002384888.1 218551097 7123936 3947640..3948239 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3948239 yiiQ 7123936 yiiQ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384888.1 3947640 D 585054 CDS YP_002384889.1 218551098 7123935 3948347..3949114 1 NC_011740.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 3949114 tpiA 7123935 tpiA Escherichia fergusonii ATCC 35469 triosephosphate isomerase YP_002384889.1 3948347 D 585054 CDS YP_002384890.1 218551099 7122150 complement(3949170..3949961) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86008270, 2995360, 3158524; Product type e : enzyme; CDP-diacylglycerol pyrophosphatase 3949961 cdh 7122150 cdh Escherichia fergusonii ATCC 35469 CDP-diacylglycerol pyrophosphatase YP_002384890.1 3949170 R 585054 CDS YP_002384891.1 218551100 7120875 complement(3950023..3951012) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91161616, 2002055, 3158524, 8774726, 9298646; Product type t : transporter; sulfate transporter subunit 3951012 sbp 7120875 sbp Escherichia fergusonii ATCC 35469 sulfate transporter subunit YP_002384891.1 3950023 R 585054 CDS YP_002384892.1 218551101 7121753 complement(3951169..3952131) 1 NC_011740.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 3952131 pfkA 7121753 pfkA Escherichia fergusonii ATCC 35469 6-phosphofructokinase YP_002384892.1 3951169 R 585054 CDS YP_002384893.1 218551102 7122581 complement(3952312..3953214) 1 NC_011740.1 member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers; ferrous iron efflux protein F 3953214 fieF 7122581 fieF Escherichia fergusonii ATCC 35469 ferrous iron efflux protein F YP_002384893.1 3952312 R 585054 CDS YP_002384894.1 218551103 7120018 complement(3953364..3953864) 1 NC_011740.1 repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; repressor CpxP 3953864 cpxP 7120018 cpxP Escherichia fergusonii ATCC 35469 repressor CpxP YP_002384894.1 3953364 R 585054 CDS YP_002384895.1 218551104 7122799 3954015..3954713 1 NC_011740.1 response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; DNA-binding transcriptional regulator CpxR 3954713 cpxR 7122799 cpxR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator CpxR YP_002384895.1 3954015 D 585054 CDS YP_002384896.1 218551105 7122800 3954710..3956083 1 NC_011740.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein 3956083 cpxA 7122800 cpxA Escherichia fergusonii ATCC 35469 two-component sensor protein YP_002384896.1 3954710 D 585054 CDS YP_002384897.1 218551106 7122798 complement(3956143..3956817) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3956817 yiiM 7122798 yiiM Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384897.1 3956143 R 585054 CDS YP_002384898.1 218551107 7121856 complement(3956887..3957507) 1 NC_011740.1 SodA; manganese binding; only present under aerobic conditions; destroys free radicals; superoxide dismutase 3957507 sodA 7121856 sodA Escherichia fergusonii ATCC 35469 superoxide dismutase YP_002384898.1 3956887 R 585054 CDS YP_002384899.1 218551108 7123926 3957794..3958828 1 NC_011740.1 transports L-rhamnose and L-lyxose into the cell; rhamnose-proton symporter 3958828 rhaT 7123926 rhaT Escherichia fergusonii ATCC 35469 rhamnose-proton symporter YP_002384899.1 3957794 D 585054 CDS YP_002384900.1 218551109 7121399 complement(3958825..3959712) 1 NC_011740.1 activates the expression of rhaRS in response to L-rhamnose; transcriptional activator RhaR 3959712 rhaR 7121399 rhaR Escherichia fergusonii ATCC 35469 transcriptional activator RhaR YP_002384900.1 3958825 R 585054 CDS YP_002384901.1 218551110 7123314 complement(3959745..3960581) 1 NC_011740.1 activates the expression of the rhaBAD operon and rhaT gene; transcriptional activator RhaS 3960581 rhaS 7123314 rhaS Escherichia fergusonii ATCC 35469 transcriptional activator RhaS YP_002384901.1 3959745 R 585054 CDS YP_002384902.1 218551111 7121398 3960870..3962339 1 NC_011740.1 catalyzes the ATP-dependent phosphorylation of rhamnulose; rhamnulokinase 3962339 rhaB 7121398 rhaB Escherichia fergusonii ATCC 35469 rhamnulokinase YP_002384902.1 3960870 D 585054 CDS YP_002384903.1 218551112 7123861 3962336..3963595 1 NC_011740.1 catalyzes the formation of L-rhamnulose from L-rhamnose; L-rhamnose isomerase 3963595 rhaA 7123861 rhaA Escherichia fergusonii ATCC 35469 L-rhamnose isomerase YP_002384903.1 3962336 D 585054 CDS YP_002384904.1 218551113 7121396 3963678..3964502 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90128204, 93374854, 8396120; Product type e : enzyme; rhamnulose-1-phosphate aldolase 3964502 rhaD 7121396 rhaD Escherichia fergusonii ATCC 35469 rhamnulose-1-phosphate aldolase YP_002384904.1 3963678 D 585054 CDS YP_002384905.1 218551114 7121397 3964526..3965722 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; alcohol dehydrogenase 3965722 7121397 EFER_3870 Escherichia fergusonii ATCC 35469 alcohol dehydrogenase YP_002384905.1 3964526 D 585054 CDS YP_002384906.1 218551115 7120323 3965719..3966033 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15060078; Product type e : enzyme; L-rhamnose mutarotase 3966033 yiiL 7120323 yiiL Escherichia fergusonii ATCC 35469 L-rhamnose mutarotase YP_002384906.1 3965719 D 585054 CDS YP_002384907.1 218551116 7121855 3966335..3966781 1 NC_011740.1 with FrvBRX is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system involved in the transport and phosphorylation of sugars; possibly responsible for the sugar specificity of the system; fructose-like phosphotransferase system subunit EIIA 3966781 frvA 7121855 frvA Escherichia fergusonii ATCC 35469 fructose-like phosphotransferase system subunit EIIA YP_002384907.1 3966335 D 585054 CDS YP_002384908.1 218551117 7123017 3966792..3968243 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 94290319; Product type t : transporter; PTS system transporter subunits IIBC 3968243 frvB 7123017 frvB Escherichia fergusonii ATCC 35469 PTS system transporter subunits IIBC YP_002384908.1 3966792 D 585054 CDS YP_002384909.1 218551118 7123018 3968233..3969303 1 NC_011740.1 with FrvABR is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system which may be involved in the transport and phosphorylation of sugars; fructose-specific phosphotransferase system protein FrvX 3969303 frvX 7123018 frvX Escherichia fergusonii ATCC 35469 fructose-specific phosphotransferase system protein FrvX YP_002384909.1 3968233 D 585054 CDS YP_002384910.1 218551119 7123020 3969303..3971051 1 NC_011740.1 repressor of the frv operon, involved in phosphoenolpyruvate:sugar phosphotransferase system; frv operon regulatory protein 3971051 frvR 7123020 frvR Escherichia fergusonii ATCC 35469 frv operon regulatory protein YP_002384910.1 3969303 D 585054 CDS YP_002384911.1 218551120 7123019 3971167..3977481 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3304658, 1693333; Product type f : factor; intimin 3977481 7123019 EFER_3876 Escherichia fergusonii ATCC 35469 intimin YP_002384911.1 3971167 D 585054 CDS YP_002384912.1 218551121 7121854 complement(3978838..3981144) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3981144 7121854 EFER_3879 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384912.1 3978838 R 585054 CDS YP_002384913.1 218551122 7120325 complement(3981146..3982981) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2124707; Product type f : factor; Hsp90xo molecular chaperone 3982981 htpG 7120325 htpG Escherichia fergusonii ATCC 35469 Hsp90xo molecular chaperone YP_002384913.1 3981146 R 585054 CDS YP_002384914.1 218551123 7123446 complement(3983292..3984128) 1 NC_011740.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein 3984128 fdhD 7123446 fdhD Escherichia fergusonii ATCC 35469 formate dehydrogenase accessory protein YP_002384914.1 3983292 R 585054 CDS YP_002384915.1 218551124 7119994 3984322..3987372 1 NC_011740.1 Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; formate dehydrogenase-O, large subunit 3987372 fdoG 7119994 fdoG Escherichia fergusonii ATCC 35469 formate dehydrogenase-O, large subunit YP_002384915.1 3984322 D 585054 CDS YP_002384916.1 218551125 7119999 3987385..3988287 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91317715, 8522521, 9852007; Product type c : carrier; formate dehydrogenase-O, Fe-S subunit 3988287 fdoH 7119999 fdoH Escherichia fergusonii ATCC 35469 formate dehydrogenase-O, Fe-S subunit YP_002384916.1 3987385 D 585054 CDS YP_002384917.1 218551126 7120000 3988284..3988919 1 NC_011740.1 cytochrome b556(FDO) component; heme containing; formate dehydrogenase-O subunit gamma 3988919 fdoI 7120000 fdoI Escherichia fergusonii ATCC 35469 formate dehydrogenase-O subunit gamma YP_002384917.1 3988284 D 585054 CDS YP_002384918.1 218551127 7120001 3988916..3989845 1 NC_011740.1 required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE 3989845 fdhE 7120001 fdhE Escherichia fergusonii ATCC 35469 formate dehydrogenase accessory protein FdhE YP_002384918.1 3988916 D 585054 CDS YP_002384919.1 218551128 7119995 complement(3990190..3990438) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator 3990438 yiiE 7119995 yiiE Escherichia fergusonii ATCC 35469 transcriptional regulator YP_002384919.1 3990190 R 585054 CDS YP_002384920.1 218551129 7121852 complement(3990826..3991104) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3991104 7121852 EFER_3888 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384920.1 3990826 R 585054 CDS YP_002384921.1 218551130 7120326 complement(3991547..3992536) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; acetyltransferase 3992536 yiiD 7120326 yiiD Escherichia fergusonii ATCC 35469 acetyltransferase YP_002384921.1 3991547 R 585054 CDS YP_002384922.1 218551131 7121851 complement(3992533..3992970) 1 NC_011740.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 3992970 dtd 7121851 dtd Escherichia fergusonii ATCC 35469 D-tyrosyl-tRNA(Tyr) deacylase YP_002384922.1 3992533 R 585054 CDS YP_002384923.1 218551132 7124130 complement(3992967..3993839) 1 NC_011740.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN 3993839 rbn 7124130 rbn Escherichia fergusonii ATCC 35469 ribonuclease BN YP_002384923.1 3992967 R 585054 CDS YP_002384924.1 218551133 7122347 complement(3993833..3994432) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; phosphatase 3994432 yihX 7122347 yihX Escherichia fergusonii ATCC 35469 phosphatase YP_002384924.1 3993833 R 585054 CDS YP_002384925.1 218551134 7121850 3994785..3995630 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3995630 7121850 EFER_3895 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384925.1 3994785 D 585054 CDS YP_002384926.1 218551135 7123681 3995631..3996677 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3996677 7123681 EFER_3896 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384926.1 3995631 D 585054 CDS YP_002384927.1 218551136 7120327 3996670..3997542 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; metal-dependent hydrolase 3997542 7120327 EFER_3897 Escherichia fergusonii ATCC 35469 metal-dependent hydrolase YP_002384927.1 3996670 D 585054 CDS YP_002384928.1 218551137 7120328 3997523..3998773 1 NC_011740.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3998773 7120328 EFER_3898 Escherichia fergusonii ATCC 35469 coproporphyrinogen III oxidase YP_002384928.1 3997523 D 585054 CDS YP_002384929.1 218551138 7123682 3998770..3999627 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3999627 7123682 EFER_3899 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384929.1 3998770 D 585054 CDS YP_002384930.1 218551139 7120913 3999624..4000319 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15808744; Product type pe : enzyme; phosphatase 4000319 7120913 EFER_3900 Escherichia fergusonii ATCC 35469 phosphatase YP_002384930.1 3999624 D 585054 CDS YP_002384931.1 218551140 7120976 complement(4000410..4002233) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9642082, 7783627, 9298646, 9622352; Product type f : factor; GTP-binding protein 4002233 bipA 7120976 bipA Escherichia fergusonii ATCC 35469 GTP-binding protein YP_002384931.1 4000410 R 585054 CDS YP_002384932.1 218551141 7121671 4002326..4002478 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4002478 7121671 EFER_3902 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384932.1 4002326 D 585054 CDS YP_002384933.1 218551142 7123785 4002606..4004015 1 NC_011740.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; glutamine synthetase 4004015 glnA 7123785 glnA Escherichia fergusonii ATCC 35469 glutamine synthetase YP_002384933.1 4002606 D 585054 CDS YP_002384934.1 218551143 7120193 4004189..4005238 1 NC_011740.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation; nitrogen regulation protein NR(II) 4005238 glnL 7120193 glnL Escherichia fergusonii ATCC 35469 nitrogen regulation protein NR(II) YP_002384934.1 4004189 D 585054 CDS YP_002384935.1 218551144 7120199 4005250..4006659 1 NC_011740.1 response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54; nitrogen regulation protein NR(I) 4006659 glnG 7120199 glnG Escherichia fergusonii ATCC 35469 nitrogen regulation protein NR(I) YP_002384935.1 4005250 D 585054 CDS YP_002384936.1 218551145 7120197 complement(4007011..4008036) 1 NC_011740.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase 4008036 tdh 7120197 tdh Escherichia fergusonii ATCC 35469 L-threonine 3-dehydrogenase YP_002384936.1 4007011 R 585054 CDS YP_002384937.1 218551146 7121983 complement(4008046..4009914) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8157607; Product type e : enzyme; 2-amino-3-ketobutyrate coenzyme A ligase 4009914 kbl 7121983 kbl Escherichia fergusonii ATCC 35469 2-amino-3-ketobutyrate coenzyme A ligase YP_002384937.1 4008046 R 585054 CDS YP_002384938.1 218551147 7123757 4009456..4010388 1 NC_011740.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase 4010388 rfaD 7123757 rfaD Escherichia fergusonii ATCC 35469 ADP-L-glycero-D-manno-heptose-6-epimerase YP_002384938.1 4009456 D 585054 CDS YP_002384939.1 218551148 7122661 4010398..4011444 1 NC_011740.1 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core; ADP-heptose--LPS heptosyltransferase 4011444 waaF 7122661 waaF Escherichia fergusonii ATCC 35469 ADP-heptose--LPS heptosyltransferase YP_002384939.1 4010398 D 585054 CDS YP_002384940.1 218551149 7122662 4011448..4012404 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20507564, 92250420, 93239678, 9446588, 1624462, 8478319; Product type e : enzyme; ADP-heptose--LPS heptosyltransferase 4012404 waaC 7122662 waaC Escherichia fergusonii ATCC 35469 ADP-heptose--LPS heptosyltransferase YP_002384940.1 4011448 D 585054 CDS YP_002384941.1 218551150 7122660 4012443..4013660 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1657881; Product type e : enzyme; O-antigen ligase 4013660 rfaL 7122660 rfaL Escherichia fergusonii ATCC 35469 O-antigen ligase YP_002384941.1 4012443 D 585054 CDS YP_002384942.1 218551151 7121389 complement(4013713..4014855) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1657881; Product type e : enzyme; Lipopolysaccharide 1, 2-N-acetylglucosaminetransferase 4014855 rfaK 7121389 rfaK Escherichia fergusonii ATCC 35469 Lipopolysaccharide 1, 2-N-acetylglucosaminetransferase YP_002384942.1 4013713 R 585054 CDS YP_002384943.1 218551152 7121388 complement(4014908..4015717) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12591884, 92250420, 92325067, 93054344; Product type pe : enzyme; lipopolysaccharide core biosynthesis protein 4015717 waaZ 7121388 waaZ Escherichia fergusonii ATCC 35469 lipopolysaccharide core biosynthesis protein YP_002384943.1 4014908 R 585054 CDS YP_002384944.1 218551153 7123469 complement(4015789..4016487) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92250420, 92325067, 9756860; Product type e : enzyme; lipopolysaccharide core biosynthesis protein 4016487 waaY 7123469 waaY Escherichia fergusonii ATCC 35469 lipopolysaccharide core biosynthesis protein YP_002384944.1 4015789 R 585054 CDS YP_002384945.1 218551154 7122363 complement(4016505..4017521) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92210496, 92250420, 92325066, 99251135, 1624461; Product type e : enzyme; UDP-D-glucose:(galactosyl)lipopolysaccharide glucosyltransferase 4017521 waaJ 7122363 waaJ Escherichia fergusonii ATCC 35469 UDP-D-glucose:(galactosyl)lipopolysaccharide glucosyltransferase YP_002384945.1 4016505 R 585054 CDS YP_002384946.1 218551155 7122665 complement(4017561..4018580) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92210496, 92250420, 92325066, 9765561, 1624461; Product type e : enzyme; UDP-D-galactose:(glucosyl)lipopolysaccharide- alpha-1,3-D-galactosyltransferase 4018580 waaI 7122665 waaI Escherichia fergusonii ATCC 35469 UDP-D-galactose:(glucosyl)lipopolysaccharide- alpha-1,3-D-galactosyltransferase YP_002384946.1 4017561 R 585054 CDS YP_002384947.1 218551156 7122659 4019365..4020333 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 2993802; Product type pe : enzyme; transposase, IS903.B 4020333 7122659 EFER_3918 Escherichia fergusonii ATCC 35469 transposase, IS903.B YP_002384947.1 4019365 D 585054 CDS YP_002384948.1 218551157 7124081 complement(4020907..4021851) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8910446; Product type e : enzyme; UDP-glucose:glucosyl LPS a 1, 2-glucosyltransferase 4021851 7124081 EFER_3920 Escherichia fergusonii ATCC 35469 UDP-glucose:glucosyl LPS a 1, 2-glucosyltransferase YP_002384948.1 4020907 R 585054 CDS YP_002384949.1 218551158 7120978 complement(4021864..4022661) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21101922, 92121133, 92210496, 9756860, 1732225; Product type e : enzyme; kinase that phosphorylates core heptose of lipopolysaccharide 4022661 waaP 7120978 waaP Escherichia fergusonii ATCC 35469 kinase that phosphorylates core heptose of lipopolysaccharide YP_002384949.1 4021864 R 585054 CDS YP_002384950.1 218551159 7123515 complement(4022654..4023778) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92121133, 92210496, 92250420, 1447141, 1732225, 7988890; Product type e : enzyme; glucosyltransferase I 4023778 waaG 7123515 waaG Escherichia fergusonii ATCC 35469 glucosyltransferase I YP_002384950.1 4022654 R 585054 CDS YP_002384951.1 218551160 7122663 complement(4023775..4024809) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92121133, 92250420, 93054344, 9756860, 1447141, 1732225; Product type e : enzyme; lipopolysaccharide core biosynthesis protein 4024809 waaQ 7122663 waaQ Escherichia fergusonii ATCC 35469 lipopolysaccharide core biosynthesis protein YP_002384951.1 4023775 R 585054 CDS YP_002384952.1 218551161 7124016 4025251..4026528 1 NC_011740.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 4026528 kdtA 7124016 kdtA Escherichia fergusonii ATCC 35469 3-deoxy-D-manno-octulosonic-acid transferase YP_002384952.1 4025251 D 585054 CDS YP_002384953.1 218551162 7120810 4026536..4027015 1 NC_011740.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 4027015 coaD 7120810 coaD Escherichia fergusonii ATCC 35469 phosphopantetheine adenylyltransferase YP_002384953.1 4026536 D 585054 CDS YP_002384954.1 218551163 7120909 complement(4027054..4027863) 1 NC_011740.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 4027863 mutM 7120909 mutM Escherichia fergusonii ATCC 35469 formamidopyrimidine-DNA glycosylase YP_002384954.1 4027054 R 585054 CDS YP_002384955.1 218551164 7123197 complement(4027961..4028128) 1 NC_011740.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 4028128 rpmG 7123197 rpmG Escherichia fergusonii ATCC 35469 50S ribosomal protein L33 YP_002384955.1 4027961 R 585054 CDS YP_002384956.1 218551165 7123268 complement(4028149..4028385) 1 NC_011740.1 required for 70S ribosome assembly; 50S ribosomal protein L28 4028385 rpmB 7123268 rpmB Escherichia fergusonii ATCC 35469 50S ribosomal protein L28 YP_002384956.1 4028149 R 585054 CDS YP_002384957.1 218551166 7121113 complement(4028602..4029270) 1 NC_011740.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 4029270 radC 7121113 radC Escherichia fergusonii ATCC 35469 DNA repair protein RadC YP_002384957.1 4028602 R 585054 CDS YP_002384958.1 218551167 7123930 4029442..4030662 1 NC_011740.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 4030662 dfp 7123930 dfp Escherichia fergusonii ATCC 35469 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase YP_002384958.1 4029442 D 585054 CDS YP_002384959.1 218551168 7124120 4030643..4031098 1 NC_011740.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 4031098 dut 7124120 dut Escherichia fergusonii ATCC 35469 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_002384959.1 4030643 D 585054 CDS YP_002384960.1 218551169 7122930 4031205..4031801 1 NC_011740.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 4031801 slmA 7122930 slmA Escherichia fergusonii ATCC 35469 nucleoid occlusion protein YP_002384960.1 4031205 D 585054 CDS YP_002384961.1 218551170 7123992 complement(4031845..4032816) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2466573; Product type pe : enzyme; retron-type reverse transcriptase 4032816 7123992 EFER_3933 Escherichia fergusonii ATCC 35469 retron-type reverse transcriptase YP_002384961.1 4031845 R 585054 CDS YP_002384962.1 218551171 7123786 complement(4033102..4033743) 1 NC_011740.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 4033743 pyrE 7123786 pyrE Escherichia fergusonii ATCC 35469 orotate phosphoribosyltransferase YP_002384962.1 4033102 R 585054 CDS YP_002384963.1 218551172 7122335 complement(4033809..4034549) 1 NC_011740.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 4034549 rph 7122335 rph Escherichia fergusonii ATCC 35469 ribonuclease PH YP_002384963.1 4033809 R 585054 CDS YP_002384964.1 218551173 7121435 4034652..4035515 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4035515 yicC 7121435 yicC Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384964.1 4034652 D 585054 CDS YP_002384965.1 218551174 7122545 4035766..4036383 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 4036383 yicG 7122545 yicG Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384965.1 4035766 D 585054 CDS YP_002384966.1 218551175 7120834 4038321..4038944 1 NC_011740.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 4038944 gmk 7120834 gmk Escherichia fergusonii ATCC 35469 guanylate kinase YP_002384966.1 4038321 D 585054 CDS YP_002384967.1 218551176 7120594 4038999..4039274 1 NC_011740.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 4039274 rpoZ 7120594 rpoZ Escherichia fergusonii ATCC 35469 DNA-directed RNA polymerase subunit omega YP_002384967.1 4038999 D 585054 CDS YP_002384968.1 218551177 7123813 4039293..4041401 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12224635, 89255395, 93266525, 94068533, 2005134, 2549050; Product type e : enzyme; bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase 4041401 spoT 7123813 spoT Escherichia fergusonii ATCC 35469 bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase YP_002384968.1 4039293 D 585054 CDS YP_002384969.1 218551178 7121809 4041408..4042097 1 NC_011740.1 specifically modifies tRNA at position G18; tRNA guanosine-2'-O-methyltransferase 4042097 trmH 7121809 trmH Escherichia fergusonii ATCC 35469 tRNA guanosine-2'-O-methyltransferase YP_002384969.1 4041408 D 585054 CDS YP_002384970.1 218551179 7122162 4042103..4044184 1 NC_011740.1 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 4044184 recG 7122162 recG Escherichia fergusonii ATCC 35469 ATP-dependent DNA helicase RecG YP_002384970.1 4042103 D 585054 CDS YP_002384971.1 218551180 7119960 complement(4044169..4045035) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4045035 7119960 EFER_3945 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384971.1 4044169 R 585054 CDS YP_002384972.1 218551181 7120979 complement(4045038..4046243) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91203811, 93106943, 1544582, 2017136, 2254324; Product type t : transporter; glutamate transporter 4046243 gltS 7120979 gltS Escherichia fergusonii ATCC 35469 glutamate transporter YP_002384972.1 4045038 R 585054 CDS YP_002384973.1 218551182 7120587 4046474..4047865 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter 4047865 yicE 7120587 yicE Escherichia fergusonii ATCC 35469 transporter YP_002384973.1 4046474 D 585054 CDS YP_002384974.1 218551183 7123495 4047987..4049696 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4049696 yicH 7123495 yicH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384974.1 4047987 D 585054 CDS YP_002384975.1 218551184 7121816 complement(4049748..4052066) 1 NC_011740.1 catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides; alpha-xylosidase 4052066 yicI 7121816 yicI Escherichia fergusonii ATCC 35469 alpha-xylosidase YP_002384975.1 4049748 R 585054 CDS YP_002384976.1 218551185 7121817 complement(4052076..4053458) 1 NC_011740.1 may be involved in the transport of galactosides-pentoses-hexuronides; transporter 4053458 yicJ 7121817 yicJ Escherichia fergusonii ATCC 35469 transporter YP_002384976.1 4052076 R 585054 CDS YP_002384977.1 218551186 7123093 4053769..4054935 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4054935 7123093 EFER_3951 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384977.1 4053769 D 585054 CDS YP_002384978.1 218551187 7120980 4055128..4055625 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4055625 7120980 EFER_3952 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384978.1 4055128 D 585054 CDS YP_002384979.1 218551188 7120981 4055749..4056705 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 4056705 yicL 7120981 yicL Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384979.1 4055749 D 585054 CDS YP_002384980.1 218551189 7121819 4056819..4057112 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4057112 yicS 7121819 yicS Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384980.1 4056819 D 585054 CDS YP_002384981.1 218551190 7121820 complement(4057149..4058141) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15223311; Product type pr : regulator; LacI family transcriptional regulator 4058141 7121820 EFER_3955 Escherichia fergusonii ATCC 35469 LacI family transcriptional regulator YP_002384981.1 4057149 R 585054 CDS YP_002384982.1 218551191 7120982 4058388..4058711 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; PTS system cellobiose/chitosan transporter subunit IIB 4058711 7120982 EFER_3956 Escherichia fergusonii ATCC 35469 PTS system cellobiose/chitosan transporter subunit IIB YP_002384982.1 4058388 D 585054 CDS YP_002384983.1 218551192 7120983 4058724..4060055 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; PTS system cellobiose/chitosan transporter subunit IIC 4060055 7120983 EFER_3957 Escherichia fergusonii ATCC 35469 PTS system cellobiose/chitosan transporter subunit IIC YP_002384983.1 4058724 D 585054 CDS YP_002384984.1 218551193 7120984 4060055..4061473 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; glycosyl phosphatase 4061473 7120984 EFER_3958 Escherichia fergusonii ATCC 35469 glycosyl phosphatase YP_002384984.1 4060055 D 585054 CDS YP_002384985.1 218551194 7120985 4061455..4061772 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; chitobiose/cellobiose phosphotransferase enzyme IIA component 4061772 7120985 EFER_3959 Escherichia fergusonii ATCC 35469 chitobiose/cellobiose phosphotransferase enzyme IIA component YP_002384985.1 4061455 D 585054 CDS YP_002384986.1 218551195 7120986 4061959..4063353 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; outer membrane porin 4063353 7120986 EFER_3960 Escherichia fergusonii ATCC 35469 outer membrane porin YP_002384986.1 4061959 D 585054 CDS YP_002384987.1 218551196 7120987 complement(4063372..4063824) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4063824 yicN 7120987 yicN Escherichia fergusonii ATCC 35469 hypothetical protein YP_002384987.1 4063372 R 585054 CDS YP_002384988.1 218551197 7123929 4064110..4065876 1 NC_011740.1 catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type; cryptic adenine deaminase 4065876 ade 7123929 ade Escherichia fergusonii ATCC 35469 cryptic adenine deaminase YP_002384988.1 4064110 D 585054 CDS YP_002384989.1 218551198 7122273 complement(4065923..4067314) 1 NC_011740.1 cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate; sugar phosphate antiporter 4067314 uhpT 7122273 uhpT Escherichia fergusonii ATCC 35469 sugar phosphate antiporter YP_002384989.1 4065923 R 585054 CDS YP_002384990.1 218551199 7122630 complement(4067452..4068771) 1 NC_011740.1 membrane protein regulates uhpT expression; regulatory protein UhpC 4068771 uhpC 7122630 uhpC Escherichia fergusonii ATCC 35469 regulatory protein UhpC YP_002384990.1 4067452 R 585054 CDS YP_002384991.1 218551200 7122629 complement(4068781..4070283) 1 NC_011740.1 Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph; sensory histidine kinase UhpB 4070283 uhpB 7122629 uhpB Escherichia fergusonii ATCC 35469 sensory histidine kinase UhpB YP_002384991.1 4068781 R 585054 CDS YP_002384992.1 218551201 7123510 complement(4070283..4070873) 1 NC_011740.1 response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter; DNA-binding transcriptional activator UhpA 4070873 uhpA 7123510 uhpA Escherichia fergusonii ATCC 35469 DNA-binding transcriptional activator UhpA YP_002384992.1 4070283 R 585054 CDS YP_002384993.1 218551202 7123509 complement(4070946..4071236) 1 NC_011740.1 with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit; acetolactate synthase 1 regulatory subunit 4071236 ilvN 7123509 ilvN Escherichia fergusonii ATCC 35469 acetolactate synthase 1 regulatory subunit YP_002384993.1 4070946 R 585054 CDS YP_002384994.1 218551203 7120735 complement(4071240..4072928) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2989782, 85242083, 92380929, 2989781; Product type e : enzyme; acetolactate synthase catalytic subunit 4072928 ilvB 7120735 ilvB Escherichia fergusonii ATCC 35469 acetolactate synthase catalytic subunit YP_002384994.1 4071240 R 585054 CDS YP_002384996.1 218551204 7120727 complement(4073034..4073132) 1 NC_011740.1 Evidence 1c : Function experimentally demonstrated in the studied genus; Product type l : leader peptide; ilvB operon leader peptide 4073132 ivbL 7120727 ivbL Escherichia fergusonii ATCC 35469 ilvB operon leader peptide YP_002384996.1 4073034 R 585054 CDS YP_002384997.1 218551205 7123755 4074065..4075249 1 NC_011740.1 multidrug efflux protein involved in adaptation to low energy shock; multidrug resistance protein D 4075249 emrD 7123755 emrD Escherichia fergusonii ATCC 35469 multidrug resistance protein D YP_002384997.1 4074065 D 585054 CDS YP_002384998.1 218551206 7122947 complement(4075273..4076205) 1 NC_011740.1 regulates the synthesis and expression of the dsdXA operon and dadA gene; DNA-binding transcriptional regulator DsdC 4076205 dsdC 7122947 dsdC Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator DsdC YP_002384998.1 4075273 R 585054 CDS YP_002384999.1 218551207 7124129 4076418..4077755 1 NC_011740.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; permease DsdX 4077755 dsdX 7124129 dsdX Escherichia fergusonii ATCC 35469 permease DsdX YP_002384999.1 4076418 D 585054 CDS YP_002385000.1 218551208 7122924 4077773..4079101 1 NC_011740.1 catalyzes the formation of pyruvate from serine; D-serine dehydratase 4079101 dsdA 7122924 dsdA Escherichia fergusonii ATCC 35469 D-serine dehydratase YP_002385000.1 4077773 D 585054 CDS YP_002385001.1 218551209 7124128 complement(4079109..4079618) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11222759; Product type pr : regulator; sulfur metabolism regulator 4079618 7124128 EFER_3974 Escherichia fergusonii ATCC 35469 sulfur metabolism regulator YP_002385001.1 4079109 R 585054 CDS YP_002385002.1 218551210 7123787 complement(4079631..4080017) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 4080017 yidG 7123787 yidG Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385002.1 4079631 R 585054 CDS YP_002385003.1 218551211 7121825 complement(4079983..4080330) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 4080330 yidH 7121825 yidH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385003.1 4079983 R 585054 CDS YP_002385004.1 218551212 7121826 complement(4080650..4081972) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; 6-phospho-glucosidase 4081972 7121826 EFER_3977 Escherichia fergusonii ATCC 35469 6-phospho-glucosidase YP_002385004.1 4080650 R 585054 CDS YP_002385005.1 218551213 7120988 complement(4081972..4083582) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; PTS system alpha-glucoside-specific transporter subunit IICB 4083582 7120988 EFER_3978 Escherichia fergusonii ATCC 35469 PTS system alpha-glucoside-specific transporter subunit IICB YP_002385005.1 4081972 R 585054 CDS YP_002385006.1 218551214 7120989 4083877..4084593 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator 4084593 yidP 7120989 yidP Escherichia fergusonii ATCC 35469 transcriptional regulator YP_002385006.1 4083877 D 585054 CDS YP_002385007.1 218551215 7121827 complement(4084590..4086359) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1356969; Product type pt : transporter; hypothetical protein 4086359 yidE 7121827 yidE Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385007.1 4084590 R 585054 CDS YP_002385008.1 218551216 7121824 complement(4086373..4086840) 1 NC_011740.1 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent; heat shock chaperone IbpB 4086840 ibpB 7121824 ibpB Escherichia fergusonii ATCC 35469 heat shock chaperone IbpB YP_002385008.1 4086373 R 585054 CDS YP_002385009.1 218551217 7120719 complement(4086913..4087326) 1 NC_011740.1 with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; heat shock protein IbpA 4087326 ibpA 7120719 ibpA Escherichia fergusonii ATCC 35469 heat shock protein IbpA YP_002385009.1 4086913 R 585054 CDS YP_002385010.1 218551218 7120718 4087632..4087964 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 4087964 yidQ 7120718 yidQ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385010.1 4087632 D 585054 CDS YP_002385011.1 218551219 7121828 complement(4087966..4089180) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4089180 yidR 7121828 yidR Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385011.1 4087966 R 585054 CDS YP_002385012.1 218551220 7121829 4089260..4090381 1 NC_011740.1 FAD/NAD(P)-binding domain; oxidoreductase 4090381 cbrA 7121829 cbrA Escherichia fergusonii ATCC 35469 oxidoreductase YP_002385012.1 4089260 D 585054 CDS YP_002385013.1 218551221 7120863 complement(4090342..4091634) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 79020349; Product type t : transporter; D-galactonate transporter 4091634 dgoT 7120863 dgoT Escherichia fergusonii ATCC 35469 D-galactonate transporter YP_002385013.1 4090342 R 585054 CDS YP_002385014.1 218551222 7122896 complement(4091754..4092902) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 79020349; Product type e : enzyme; galactonate dehydratase 4092902 dgoD 7122896 dgoD Escherichia fergusonii ATCC 35469 galactonate dehydratase YP_002385014.1 4091754 R 585054 CDS YP_002385015.1 218551223 7122894 complement(4092899..4093516) 1 NC_011740.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase 4093516 dgoA 7122894 dgoA Escherichia fergusonii ATCC 35469 2-dehydro-3-deoxy-6-phosphogalactonate aldolase YP_002385015.1 4092899 R 585054 CDS YP_002385016.1 218551224 7122893 complement(4093500..4094378) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 79020349; Product type e : enzyme; 2-oxo-3-deoxygalactonate kinase 4094378 dgoK 7122893 dgoK Escherichia fergusonii ATCC 35469 2-oxo-3-deoxygalactonate kinase YP_002385016.1 4093500 R 585054 CDS YP_002385017.1 218551225 7122895 complement(4094375..4095064) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 79020349; Product type pr : regulator; DNA-binding transcriptional regulator 4095064 dgoR 7122895 dgoR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YP_002385017.1 4094375 R 585054 CDS YP_002385018.1 218551226 7124121 4095342..4095998 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; hypothetical protein 4095998 yidX 7124121 yidX Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385018.1 4095342 D 585054 CDS YP_002385019.1 218551227 7121830 complement(4096044..4096856) 1 NC_011740.1 YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins; sugar phosphatase 4096856 yidA 7121830 yidA Escherichia fergusonii ATCC 35469 sugar phosphatase YP_002385019.1 4096044 R 585054 CDS YP_002385020.1 218551228 7121821 complement(4096971..4097369) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4097369 yidB 7121821 yidB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385020.1 4096971 R 585054 CDS YP_002385021.1 218551229 7123382 complement(4097535..4099949) 1 NC_011740.1 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 4099949 gyrB 7123382 gyrB Escherichia fergusonii ATCC 35469 DNA gyrase subunit B YP_002385021.1 4097535 R 585054 CDS YP_002385022.1 218551230 7120628 complement(4099978..4101051) 1 NC_011740.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 4101051 recF 7120628 recF Escherichia fergusonii ATCC 35469 recombination protein F YP_002385022.1 4099978 R 585054 CDS YP_002385023.1 218551231 7122362 complement(4101051..4102151) 1 NC_011740.1 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 4102151 dnaN 7122362 dnaN Escherichia fergusonii ATCC 35469 DNA polymerase III subunit beta YP_002385023.1 4101051 R 585054 CDS YP_002385024.1 218551232 7122913 complement(4102156..4103568) 1 NC_011740.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 4103568 dnaA 7122913 dnaA Escherichia fergusonii ATCC 35469 chromosomal replication initiation protein YP_002385024.1 4102156 R 585054 CDS YP_002385025.1 218551233 7124123 4104163..4104303 1 NC_011740.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 4104303 rpmH 7124123 rpmH Escherichia fergusonii ATCC 35469 50S ribosomal protein L34 YP_002385025.1 4104163 D 585054 CDS YP_002385026.1 218551234 7123269 4104320..4104679 1 NC_011740.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 4104679 rnpA 7123269 rnpA Escherichia fergusonii ATCC 35469 ribonuclease P YP_002385026.1 4104320 D 585054 CDS YP_002385027.1 218551235 7123867 4104643..4104900 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4104900 yidD 7123867 yidD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385027.1 4104643 D 585054 CDS YP_002385028.1 218551236 7121823 4104903..4106549 1 NC_011740.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 4106549 yidC 7121823 yidC Escherichia fergusonii ATCC 35469 inner membrane protein translocase component YidC YP_002385028.1 4104903 D 585054 CDS YP_002385029.1 218551237 7121822 4106655..4108019 1 NC_011740.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 4108019 trmE 7121822 trmE Escherichia fergusonii ATCC 35469 tRNA modification GTPase TrmE YP_002385029.1 4106655 D 585054 CDS YP_002385030.1 218551238 7123989 4108262..4108336 1 NC_011740.1 Evidence 1c : Function experimentally demonstrated in the studied genus; Product type l : leader peptide; tryptophanase leader peptide 4108336 tnaC 7123989 tnaC Escherichia fergusonii ATCC 35469 tryptophanase leader peptide YP_002385030.1 4108262 D 585054 CDS YP_002385031.1 218551239 7122139 4108557..4109972 1 NC_011740.1 tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan; tryptophanase 4109972 tnaA 7122139 tnaA Escherichia fergusonii ATCC 35469 tryptophanase YP_002385031.1 4108557 D 585054 CDS YP_002385032.1 218551240 7122137 4110064..4111311 1 NC_011740.1 tryptophan transporter of low affinity; tryptophan permease TnaB 4111311 tnaB 7122137 tnaB Escherichia fergusonii ATCC 35469 tryptophan permease TnaB YP_002385032.1 4110064 D 585054 CDS YP_002385033.1 218551241 7122138 4111444..4112619 1 NC_011740.1 Confers resistance to chloramphenicol; multidrug efflux system protein MdtL 4112619 mdtL 7122138 mdtL Escherichia fergusonii ATCC 35469 multidrug efflux system protein MdtL YP_002385033.1 4111444 D 585054 CDS YP_002385034.1 218551242 7121255 4112585..4113553 1 NC_011740.1 Involved in anaerobic NO protection; DNA-binding transcriptional regulator YidZ 4113553 yidZ 7121255 yidZ Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YidZ YP_002385034.1 4112585 D 585054 CDS YP_002385035.1 218551243 7123931 4113701..4114450 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; phosphopantetheinyl transferase 4114450 7123931 EFER_4008 Escherichia fergusonii ATCC 35469 phosphopantetheinyl transferase YP_002385035.1 4113701 D 585054 CDS YP_002385036.1 218551244 7123788 4114461..4115027 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14766567; Product type e : enzyme; chromate reductase, Class I, flavoprotein 4115027 yieF 7123788 yieF Escherichia fergusonii ATCC 35469 chromate reductase, Class I, flavoprotein YP_002385036.1 4114461 D 585054 CDS YP_002385037.1 218551245 7123383 complement(4115109..4115264) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4115264 7123383 EFER_4010 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385037.1 4115109 R 585054 CDS YP_002385038.1 218551246 7120990 complement(4115268..4115459) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4115459 7120990 EFER_4011 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385038.1 4115268 R 585054 CDS YP_002385039.1 218551247 7120991 complement(4115505..4116842) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 4116842 yieG 7120991 yieG Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385039.1 4115505 R 585054 CDS YP_002385040.1 218551248 7121831 4117008..4117673 1 NC_011740.1 YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily; 6-phosphogluconate phosphatase 4117673 yieH 7121831 yieH Escherichia fergusonii ATCC 35469 6-phosphogluconate phosphatase YP_002385040.1 4117008 D 585054 CDS YP_002385041.1 218551249 7121832 4117740..4118213 1 NC_011740.1 might be involved in hypersensitivity to nitrofurzone; inner membrane protein 4118213 yieI 7121832 yieI Escherichia fergusonii ATCC 35469 inner membrane protein YP_002385041.1 4117740 D 585054 CDS YP_002385042.1 218551250 7121833 4118262..4118843 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4118843 7121833 EFER_4015 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385042.1 4118262 D 585054 CDS YP_002385043.1 218551251 7120992 complement(4118899..4119615) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; 6-phosphogluconolactonase 4119615 yieK 7120992 yieK Escherichia fergusonii ATCC 35469 6-phosphogluconolactonase YP_002385043.1 4118899 R 585054 CDS YP_002385044.1 218551252 7121834 complement(4119630..4120826) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; xylanase 4120826 yieL 7121834 yieL Escherichia fergusonii ATCC 35469 xylanase YP_002385044.1 4119630 R 585054 CDS YP_002385045.1 218551253 7121835 complement(4120826..4122442) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10027967; Product type t : transporter; carbohydrate-specific outer membrane porin, cryptic 4122442 bglH 7121835 bglH Escherichia fergusonii ATCC 35469 carbohydrate-specific outer membrane porin, cryptic YP_002385045.1 4120826 R 585054 CDS YP_002385046.1 218551254 7123359 complement(4122527..4123921) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87222180, 88297127, 92334140, 3034860, 3309161; Product type e : enzyme; cryptic phospho-beta-glucosidase B 4123921 bglB 7123359 bglB Escherichia fergusonii ATCC 35469 cryptic phospho-beta-glucosidase B YP_002385046.1 4122527 R 585054 CDS YP_002385047.1 218551255 7121661 complement(4123940..4125889) 1 NC_011740.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system beta-glucoside-specific transporter subunit IIABC 4125889 bglF 7121661 bglF Escherichia fergusonii ATCC 35469 PTS system beta-glucoside-specific transporter subunit IIABC YP_002385047.1 4123940 R 585054 CDS YP_002385048.1 218551256 7121662 complement(4125948..4126784) 1 NC_011740.1 positive regulator of the beta-glucoside operon; transcriptional antiterminator; transcriptional antiterminator BglG 4126784 bglG 7121662 bglG Escherichia fergusonii ATCC 35469 transcriptional antiterminator BglG YP_002385048.1 4125948 R 585054 CDS YP_002385049.1 218551257 7121663 complement(4127070..4127795) 1 NC_011740.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon; transcriptional regulator PhoU 4127795 phoU 7121663 phoU Escherichia fergusonii ATCC 35469 transcriptional regulator PhoU YP_002385049.1 4127070 R 585054 CDS YP_002385050.1 218551258 7122604 complement(4127810..4128583) 1 NC_011740.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 4128583 pstB 7122604 pstB Escherichia fergusonii ATCC 35469 phosphate transporter ATP-binding protein YP_002385050.1 4127810 R 585054 CDS YP_002385051.1 218551259 7122308 complement(4128675..4129565) 1 NC_011740.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PtsA 4129565 pstA 7122308 pstA Escherichia fergusonii ATCC 35469 phosphate transporter permease subunit PtsA YP_002385051.1 4128675 R 585054 CDS YP_002385052.1 218551260 7123460 complement(4129565..4130524) 1 NC_011740.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PstC 4130524 pstC 7123460 pstC Escherichia fergusonii ATCC 35469 phosphate transporter permease subunit PstC YP_002385052.1 4129565 R 585054 CDS YP_002385053.1 218551261 7122309 complement(4130610..4131650) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90133909, 2215649, 6321434, 6365894, 9228942, 9298646, 9671506; Product type t : transporter; phosphate ABC transporter substrate-binding protein 4131650 pstS 7122309 pstS Escherichia fergusonii ATCC 35469 phosphate ABC transporter substrate-binding protein YP_002385053.1 4130610 R 585054 CDS YP_002385054.1 218551262 7122310 complement(4131921..4133750) 1 NC_011740.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 4133750 glmS 7122310 glmS Escherichia fergusonii ATCC 35469 glucosamine--fructose-6-phosphate aminotransferase YP_002385054.1 4131921 R 585054 CDS YP_002385055.1 218551263 7123119 complement(4133912..4135282) 1 NC_011740.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 4135282 glmU 7123119 glmU Escherichia fergusonii ATCC 35469 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase YP_002385055.1 4133912 R 585054 CDS YP_002385056.1 218551264 7120192 complement(4135558..4136256) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 4136256 7120192 EFER_4029 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385056.1 4135558 R 585054 CDS YP_002385057.1 218551265 7120993 complement(4136453..4136872) 1 NC_011740.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon 4136872 atpC 7120993 atpC Escherichia fergusonii ATCC 35469 F0F1 ATP synthase subunit epsilon YP_002385057.1 4136453 R 585054 CDS YP_002385058.1 218551266 7123354 complement(4136893..4138275) 1 NC_011740.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 4138275 atpD 7123354 atpD Escherichia fergusonii ATCC 35469 F0F1 ATP synthase subunit beta YP_002385058.1 4136893 R 585054 CDS YP_002385059.1 218551267 7121635 complement(4138302..4139165) 1 NC_011740.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 4139165 atpG 7121635 atpG Escherichia fergusonii ATCC 35469 F0F1 ATP synthase subunit gamma YP_002385059.1 4138302 R 585054 CDS YP_002385060.1 218551268 7121638 complement(4139216..4140757) 1 NC_011740.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 4140757 atpA 7121638 atpA Escherichia fergusonii ATCC 35469 F0F1 ATP synthase subunit alpha YP_002385060.1 4139216 R 585054 CDS YP_002385061.1 218551269 7121633 complement(4140770..4141303) 1 NC_011740.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 4141303 atpH 7121633 atpH Escherichia fergusonii ATCC 35469 F0F1 ATP synthase subunit delta YP_002385061.1 4140770 R 585054 CDS YP_002385062.1 218551270 7123900 complement(4141318..4141788) 1 NC_011740.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 4141788 atpF 7123900 atpF Escherichia fergusonii ATCC 35469 F0F1 ATP synthase subunit B YP_002385062.1 4141318 R 585054 CDS YP_002385063.1 218551271 7121637 complement(4141850..4142089) 1 NC_011740.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 4142089 atpE 7121637 atpE Escherichia fergusonii ATCC 35469 F0F1 ATP synthase subunit C YP_002385063.1 4141850 R 585054 CDS YP_002385064.1 218551272 7121636 complement(4142136..4142951) 1 NC_011740.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 4142951 atpB 7121636 atpB Escherichia fergusonii ATCC 35469 F0F1 ATP synthase subunit A YP_002385064.1 4142136 R 585054 CDS YP_002385065.1 218551273 7121634 complement(4142960..4143340) 1 NC_011740.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I 4143340 atpI 7121634 atpI Escherichia fergusonii ATCC 35469 F0F1 ATP synthase subunit I YP_002385065.1 4142960 R 585054 CDS YP_002385066.1 218551274 7121639 complement(4143955..4144578) 1 NC_011740.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 4144578 gidB 7121639 gidB Escherichia fergusonii ATCC 35469 16S rRNA methyltransferase GidB YP_002385066.1 4143955 R 585054 CDS YP_002385067.1 218551275 7123659 complement(4144642..4146531) 1 NC_011740.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 4146531 gidA 7123659 gidA Escherichia fergusonii ATCC 35469 tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_002385067.1 4144642 R 585054 CDS YP_002385068.1 218551276 7123658 complement(4146910..4147353) 1 NC_011740.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 4147353 mioC 7123658 mioC Escherichia fergusonii ATCC 35469 flavodoxin YP_002385068.1 4146910 R 585054 CDS YP_002385069.1 218551277 7120935 complement(4147443..4147901) 1 NC_011740.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC 4147901 asnC 7120935 asnC Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator AsnC YP_002385069.1 4147443 R 585054 CDS YP_002385070.1 218551278 7120569 4148053..4149045 1 NC_011740.1 catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 4149045 asnA 7120569 asnA Escherichia fergusonii ATCC 35469 asparagine synthetase AsnA YP_002385070.1 4148053 D 585054 CDS YP_002385071.1 218551279 7120567 complement(4149050..4150501) 1 NC_011740.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; hypothetical protein 4150501 yieM 7120567 yieM Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385071.1 4149050 R 585054 CDS YP_002385072.1 218551280 7121836 complement(4150495..4152015) 1 NC_011740.1 interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase; regulatory ATPase RavA 4152015 ravA 7121836 ravA Escherichia fergusonii ATCC 35469 regulatory ATPase RavA YP_002385072.1 4150495 R 585054 CDS YP_002385073.1 218551281 7122345 4152213..4154081 1 NC_011740.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH; potassium transport protein Kup 4154081 trkD 7122345 trkD Escherichia fergusonii ATCC 35469 potassium transport protein Kup YP_002385073.1 4152213 D 585054 CDS YP_002385074.1 218551282 7123434 4154248..4154667 1 NC_011740.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 4154667 rbsD 7123434 rbsD Escherichia fergusonii ATCC 35469 D-ribose pyranase YP_002385074.1 4154248 D 585054 CDS YP_002385075.1 218551283 7122350 4154675..4156180 1 NC_011740.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP-binding protein 4156180 rbsA 7122350 rbsA Escherichia fergusonii ATCC 35469 D-ribose transporter ATP-binding protein YP_002385075.1 4154675 D 585054 CDS YP_002385076.1 218551284 7122348 4156185..4157150 1 NC_011740.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease 4157150 rbsC 7122348 rbsC Escherichia fergusonii ATCC 35469 ribose ABC transporter permease YP_002385076.1 4156185 D 585054 CDS YP_002385077.1 218551285 7122349 4157175..4158065 1 NC_011740.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 4158065 rbsB 7122349 rbsB Escherichia fergusonii ATCC 35469 D-ribose transporter subunit RbsB YP_002385077.1 4157175 D 585054 CDS YP_002385078.1 218551286 7124026 4158191..4159120 1 NC_011740.1 catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 4159120 rbsK 7124026 rbsK Escherichia fergusonii ATCC 35469 ribokinase YP_002385078.1 4158191 D 585054 CDS YP_002385079.1 218551287 7122351 4159124..4160116 1 NC_011740.1 DNA-binding transcriptional repressor of ribose metabolism; transcriptional repressor RbsR 4160116 rbsR 7122351 rbsR Escherichia fergusonii ATCC 35469 transcriptional repressor RbsR YP_002385079.1 4159124 D 585054 CDS YP_002385080.1 218551288 7122352 complement(4160157..4160861) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator 4160861 yieP 7122352 yieP Escherichia fergusonii ATCC 35469 transcriptional regulator YP_002385080.1 4160157 R 585054 CDS YP_002385081.1 218551289 7120511 complement(4166477..4166920) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type pe : enzyme; hypothetical protein 4166920 yjaB 7120511 yjaB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385081.1 4166477 R 585054 CDS YP_002385082.1 218551290 7121863 4167077..4168006 1 NC_011740.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 4168006 metA 7121863 metA Escherichia fergusonii ATCC 35469 homoserine O-succinyltransferase YP_002385082.1 4167077 D 585054 CDS YP_002385083.1 218551291 7123241 4168275..4169876 1 NC_011740.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase 4169876 aceB 7123241 aceB Escherichia fergusonii ATCC 35469 malate synthase YP_002385083.1 4168275 D 585054 CDS YP_002385084.1 218551292 7123451 4169906..4171210 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91295197, 92112731, 92353108, 2836370, 3049537, 3060852, 3276689, 3290857, 3291954, 7826335; Product type e : enzyme; isocitrate lyase 4171210 aceA 7123451 aceA Escherichia fergusonii ATCC 35469 isocitrate lyase YP_002385084.1 4169906 D 585054 CDS YP_002385085.1 218551293 7124009 4171259..4172992 1 NC_011740.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol; bifunctional isocitrate dehydrogenase kinase/phosphatase 4172992 aceK 7124009 aceK Escherichia fergusonii ATCC 35469 bifunctional isocitrate dehydrogenase kinase/phosphatase YP_002385085.1 4171259 D 585054 CDS YP_002385086.1 218551294 7122259 4173017..4174474 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3029675; Product type e : enzyme; DNA cytosine methylase 4174474 7122259 EFER_4070 Escherichia fergusonii ATCC 35469 DNA cytosine methylase YP_002385086.1 4173017 D 585054 CDS YP_002385087.1 218551295 7120994 complement(4174522..4175346) 1 NC_011740.1 regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase; IclR family transcriptional regulator 4175346 iclR 7120994 iclR Escherichia fergusonii ATCC 35469 IclR family transcriptional regulator YP_002385087.1 4174522 R 585054 CDS YP_002385088.1 218551296 7120722 4175546..4179229 1 NC_011740.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 4179229 metH 7120722 metH Escherichia fergusonii ATCC 35469 B12-dependent methionine synthase YP_002385088.1 4175546 D 585054 CDS YP_002385089.1 218551297 7120920 4179283..4179609 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4179609 7120920 EFER_4073 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385089.1 4179283 D 585054 CDS YP_002385090.1 218551298 7120995 4179652..4180101 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4180101 7120995 EFER_4074 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385090.1 4179652 D 585054 CDS YP_002385091.1 218551299 7120996 4180272..4181903 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter 4181903 yjbB 7120996 yjbB Escherichia fergusonii ATCC 35469 transporter YP_002385091.1 4180272 D 585054 CDS YP_002385092.1 218551300 7121865 4181951..4182544 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15115803, 12878731, 13129938; Product type e : enzyme; nucleoprotein/polynucleotide-associated enzyme 4182544 yaiL 7121865 yaiL Escherichia fergusonii ATCC 35469 nucleoprotein/polynucleotide-associated enzyme YP_002385092.1 4181951 D 585054 CDS YP_002385093.1 218551301 7123258 complement(4182697..4183917) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968, 7652212; Product type e : enzyme; L-sorbose 1-phosphate reductase 4183917 7123258 EFER_4077 Escherichia fergusonii ATCC 35469 L-sorbose 1-phosphate reductase YP_002385093.1 4182697 R 585054 CDS YP_002385094.1 218551302 7123251 complement(4183971..4184825) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968, 7700234; Product type t : transporter; sorbose permease IID component 4184825 7123251 EFER_4078 Escherichia fergusonii ATCC 35469 sorbose permease IID component YP_002385094.1 4183971 R 585054 CDS YP_002385095.1 218551303 7120997 complement(4184806..4185603) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968, 7700234; Product type t : transporter; PTS system sorbose-specific transporter subunit IIC 4185603 7120997 EFER_4079 Escherichia fergusonii ATCC 35469 PTS system sorbose-specific transporter subunit IIC YP_002385095.1 4184806 R 585054 CDS YP_002385096.1 218551304 7120998 complement(4185671..4186162) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968, 7700234, 12662934; Product type t : transporter; PTS system sorbose-specific transporter subunit IIB 4186162 7120998 EFER_4080 Escherichia fergusonii ATCC 35469 PTS system sorbose-specific transporter subunit IIB YP_002385096.1 4185671 R 585054 CDS YP_002385097.1 218551305 7120999 complement(4186162..4186569) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968; Product type t : transporter; PTS system sorbose-specific transporter subunit IIA 4186569 7120999 EFER_4081 Escherichia fergusonii ATCC 35469 PTS system sorbose-specific transporter subunit IIA YP_002385097.1 4186162 R 585054 CDS YP_002385098.1 218551306 7121000 complement(4186579..4187430) 1 NC_011740.1 Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; sorbitol-6-phosphate 2-dehydrogenase 4187430 7121000 EFER_4082 Escherichia fergusonii ATCC 35469 sorbitol-6-phosphate 2-dehydrogenase YP_002385098.1 4186579 R 585054 CDS YP_002385099.1 218551307 7121001 complement(4187443..4188480) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968; Product type r : regulator; sorbitol/sorbose operon regulator 4188480 7121001 EFER_4083 Escherichia fergusonii ATCC 35469 sorbitol/sorbose operon regulator YP_002385099.1 4187443 R 585054 CDS YP_002385100.1 218551308 7121002 4188745..4189617 1 NC_011740.1 catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA; 23S rRNA pseudouridine synthase F 4189617 yjbC 7121002 yjbC Escherichia fergusonii ATCC 35469 23S rRNA pseudouridine synthase F YP_002385100.1 4188745 D 585054 CDS YP_002385101.1 218551309 7121868 complement(4189893..4191035) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1657881; Product type e : enzyme; lipopolysaccharide 1, 2-N-acetylglucosaminetransferase 4191035 7121868 EFER_4086 Escherichia fergusonii ATCC 35469 lipopolysaccharide 1, 2-N-acetylglucosaminetransferase YP_002385101.1 4189893 R 585054 CDS YP_002385102.1 218551310 7121867 complement(4192210..4192482) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4192482 yjbD 7121867 yjbD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385102.1 4192210 R 585054 CDS YP_002385103.1 218551311 7123939 4192796..4193008 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4193008 7123939 EFER_4089 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385103.1 4192796 D 585054 CDS YP_002385104.1 218551312 7121004 4193012..4194139 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4194139 7121004 EFER_4090 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385104.1 4193012 D 585054 CDS YP_002385105.1 218551313 7123252 4194136..4194936 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4194936 7123252 EFER_4091 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385105.1 4194136 D 585054 CDS YP_002385106.1 218551314 7121005 complement(4194966..4195694) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4195694 7121005 EFER_4092 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385106.1 4194966 R 585054 CDS YP_002385107.1 218551315 7121006 complement(4195908..4196363) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4196363 7121006 EFER_4093 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385107.1 4195908 R 585054 CDS YP_002385108.1 218551316 7123253 complement(4196360..4197067) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; phage tail fiber assembly protein 4197067 7123253 EFER_4094 Escherichia fergusonii ATCC 35469 phage tail fiber assembly protein YP_002385108.1 4196360 R 585054 CDS YP_002385109.1 218551317 7121007 complement(4197064..4198767) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; side tail phage protein 4198767 7121007 EFER_4095 Escherichia fergusonii ATCC 35469 side tail phage protein YP_002385109.1 4197064 R 585054 CDS YP_002385110.1 218551318 7121008 complement(4198644..4199378) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; phage tail protein 4199378 7121008 EFER_4096 Escherichia fergusonii ATCC 35469 phage tail protein YP_002385110.1 4198644 R 585054 CDS YP_002385111.1 218551319 7123254 complement(4199356..4200471) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; phage baseplate protein 4200471 7123254 EFER_4097 Escherichia fergusonii ATCC 35469 phage baseplate protein YP_002385111.1 4199356 R 585054 CDS YP_002385112.1 218551320 7121009 complement(4200462..4200821) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; phage baseplate protein 4200821 7121009 EFER_4098 Escherichia fergusonii ATCC 35469 phage baseplate protein YP_002385112.1 4200462 R 585054 CDS YP_002385113.1 218551321 7121010 complement(4200920..4201621) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7483254; Product type ps : structure; phage baseplate component 4201621 7121010 EFER_4099 Escherichia fergusonii ATCC 35469 phage baseplate component YP_002385113.1 4200920 R 585054 CDS YP_002385114.1 218551322 7123789 complement(4201631..4202671) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; control protein for phage late genes expression 4202671 7123789 EFER_4100 Escherichia fergusonii ATCC 35469 control protein for phage late genes expression YP_002385114.1 4201631 R 585054 CDS YP_002385115.1 218551323 7121011 complement(4202659..4202871) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; phage tail protein 4202871 7121011 EFER_4101 Escherichia fergusonii ATCC 35469 phage tail protein YP_002385115.1 4202659 R 585054 CDS YP_002385116.1 218551324 7123255 complement(4202868..4203821) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; hypothetical protein 4203821 7123255 EFER_4102 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385116.1 4202868 R 585054 CDS YP_002385117.1 218551325 7121012 complement(4203821..4206196) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; phage tail protein 4206196 7121012 EFER_4103 Escherichia fergusonii ATCC 35469 phage tail protein YP_002385117.1 4203821 R 585054 CDS YP_002385118.1 218551326 7121013 complement(4206297..4206425) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4206425 7121013 EFER_4104 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385118.1 4206297 R 585054 CDS YP_002385119.1 218551327 7123256 complement(4206385..4206702) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4206702 7123256 EFER_4105 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385119.1 4206385 R 585054 CDS YP_002385120.1 218551328 7121014 complement(4206753..4207277) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; phage tail core protein 4207277 7121014 EFER_4106 Escherichia fergusonii ATCC 35469 phage tail core protein YP_002385120.1 4206753 R 585054 CDS YP_002385121.1 218551329 7121015 complement(4207277..4208707) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1825255; Product type ps : structure; phage tail sheath protein 4208707 7121015 EFER_4107 Escherichia fergusonii ATCC 35469 phage tail sheath protein YP_002385121.1 4207277 R 585054 CDS YP_002385122.1 218551330 7123790 complement(4208691..4208888) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4208888 7123790 EFER_4108 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385122.1 4208691 R 585054 CDS YP_002385123.1 218551331 7121016 complement(4208885..4209340) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4209340 7121016 EFER_4109 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385123.1 4208885 R 585054 CDS YP_002385124.1 218551332 7121017 complement(4209458..4209772) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; inner membrane protein 4209772 7121017 EFER_4110 Escherichia fergusonii ATCC 35469 inner membrane protein YP_002385124.1 4209458 R 585054 CDS YP_002385125.1 218551333 7123791 complement(4209785..4210489) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; soluble lytic murein transglycosylase 4210489 7123791 EFER_4111 Escherichia fergusonii ATCC 35469 soluble lytic murein transglycosylase YP_002385125.1 4209785 R 585054 CDS YP_002385126.1 218551334 7121018 complement(4210393..4210680) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; inner membrane protein 4210680 7121018 EFER_4112 Escherichia fergusonii ATCC 35469 inner membrane protein YP_002385126.1 4210393 R 585054 CDS YP_002385127.1 218551335 7121019 4211218..4211562 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7715460; Product type pr : regulator; transcriptional regulator 4211562 7121019 EFER_4113 Escherichia fergusonii ATCC 35469 transcriptional regulator YP_002385127.1 4211218 D 585054 CDS YP_002385128.1 218551336 7123792 complement(4211734..4212669) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; zeta toxin; poison-antidote element 4212669 7123792 EFER_4114 Escherichia fergusonii ATCC 35469 zeta toxin; poison-antidote element YP_002385128.1 4211734 R 585054 CDS YP_002385129.1 218551337 7121020 complement(4212808..4214157) 1 NC_011740.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; aspartate kinase III 4214157 lysC 7121020 lysC Escherichia fergusonii ATCC 35469 aspartate kinase III YP_002385129.1 4212808 R 585054 CDS YP_002385130.1 218551338 7121215 4214450..4216099 1 NC_011740.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 4216099 pgi 7121215 pgi Escherichia fergusonii ATCC 35469 glucose-6-phosphate isomerase YP_002385130.1 4214450 D 585054 CDS YP_002385131.1 218551339 7122587 complement(4216435..4216683) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4216683 7122587 EFER_4118 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385131.1 4216435 R 585054 CDS YP_002385132.1 218551340 7121021 4216811..4217449 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; lipoprotein 4217449 yjbF 7121021 yjbF Escherichia fergusonii ATCC 35469 lipoprotein YP_002385132.1 4216811 D 585054 CDS YP_002385133.1 218551341 7121869 4217446..4218183 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4218183 yjbG 7121869 yjbG Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385133.1 4217446 D 585054 CDS YP_002385134.1 218551342 7121870 4218183..4220279 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; porin 4220279 yjbH 7121870 yjbH Escherichia fergusonii ATCC 35469 porin YP_002385134.1 4218183 D 585054 CDS YP_002385135.1 218551343 7121871 4220400..4220810 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10986267; Product type pm : membrane component; phosphate-starvation-inducible protein PsiE 4220810 yjbA 7121871 yjbA Escherichia fergusonii ATCC 35469 phosphate-starvation-inducible protein PsiE YP_002385135.1 4220400 D 585054 CDS YP_002385136.1 218551344 7123938 complement(4220854..4222329) 1 NC_011740.1 xylose/proton symporter; member of the major facilitator superfamily (MFS) of transporter; D-xylose transporter XylE 4222329 xylE 7123938 xylE Escherichia fergusonii ATCC 35469 D-xylose transporter XylE YP_002385136.1 4220854 R 585054 CDS YP_002385137.1 218551345 7122390 complement(4222718..4223608) 1 NC_011740.1 with MalKFE is involved in the transport of maltose into the cell; maltose transporter permease 4223608 malG 7122390 malG Escherichia fergusonii ATCC 35469 maltose transporter permease YP_002385137.1 4222718 R 585054 CDS YP_002385138.1 218551346 7121223 complement(4223621..4225165) 1 NC_011740.1 with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein 4225165 malF 7121223 malF Escherichia fergusonii ATCC 35469 maltose transporter membrane protein YP_002385138.1 4223621 R 585054 CDS YP_002385139.1 218551347 7121222 complement(4225319..4226509) 1 NC_011740.1 functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter periplasmic protein 4226509 malE 7121222 malE Escherichia fergusonii ATCC 35469 maltose ABC transporter periplasmic protein YP_002385139.1 4225319 R 585054 CDS YP_002385140.1 218551348 7123287 4226887..4228002 1 NC_011740.1 with malEFG is involved in import of maltose/maltodextrin; maltose/maltodextrin transporter ATP-binding protein 4228002 malK 7123287 malK Escherichia fergusonii ATCC 35469 maltose/maltodextrin transporter ATP-binding protein YP_002385140.1 4226887 D 585054 CDS YP_002385141.1 218551349 7121224 4228077..4229417 1 NC_011740.1 porin involved in the transport of maltose and maltodextrins; maltoporin 4229417 lamB 7121224 lamB Escherichia fergusonii ATCC 35469 maltoporin YP_002385141.1 4228077 D 585054 CDS YP_002385142.1 218551350 7120817 4229515..4230456 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87141162, 2434655, 6086106; Product type pt : transporter; maltose regulon periplasmic protein 4230456 malM 7120817 malM Escherichia fergusonii ATCC 35469 maltose regulon periplasmic protein YP_002385142.1 4229515 D 585054 CDS YP_002385143.1 218551351 7121225 4230469..4231131 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; chorismate pyruvate lyase 4231131 ubiC 7121225 ubiC Escherichia fergusonii ATCC 35469 chorismate pyruvate lyase YP_002385143.1 4230469 D 585054 CDS YP_002385144.1 218551352 7122617 4231144..4232016 1 NC_011740.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 4232016 ubiA 7122617 ubiA Escherichia fergusonii ATCC 35469 4-hydroxybenzoate octaprenyltransferase YP_002385144.1 4231144 D 585054 CDS YP_002385145.1 218551353 7122615 complement(4232073..4234493) 1 NC_011740.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase 4234493 plsB 7122615 plsB Escherichia fergusonii ATCC 35469 glycerol-3-phosphate acyltransferase YP_002385145.1 4232073 R 585054 CDS YP_002385146.1 218551354 7123642 4234664..4235032 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10220339, 6257698, 86278195, 88111690, 2984194, 6309817, 8071224; Product type e : enzyme; diacylglycerol kinase 4235032 dgkA 7123642 dgkA Escherichia fergusonii ATCC 35469 diacylglycerol kinase YP_002385146.1 4234664 D 585054 CDS YP_002385147.1 218551355 7122892 4235142..4235750 1 NC_011740.1 Represses a number of genes involved in the response to DNA damage; LexA repressor 4235750 lexA 7122892 lexA Escherichia fergusonii ATCC 35469 LexA repressor YP_002385147.1 4235142 D 585054 CDS YP_002385148.1 218551356 7120829 4235823..4237148 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87165788; Product type cp : cell process; DNA-damage-inducible SOS response protein 4237148 dinF 7120829 dinF Escherichia fergusonii ATCC 35469 DNA-damage-inducible SOS response protein YP_002385148.1 4235823 D 585054 CDS YP_002385149.1 218551357 7122898 4237280..4237489 1 NC_011740.1 unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential; stress-response protein 4237489 yjbJ 7122898 yjbJ Escherichia fergusonii ATCC 35469 stress-response protein YP_002385149.1 4237280 D 585054 CDS YP_002385150.1 218551358 7121872 complement(4237540..4238055) 1 NC_011740.1 Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB; zinc uptake transcriptional repressor 4238055 zur 7121872 zur Escherichia fergusonii ATCC 35469 zinc uptake transcriptional repressor YP_002385150.1 4237540 R 585054 CDS YP_002385151.1 218551359 7122060 4238220..4239215 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 22095566; Product type e : enzyme; tRNA-dihydrouridine synthase A 4239215 yjbN 7122060 yjbN Escherichia fergusonii ATCC 35469 tRNA-dihydrouridine synthase A YP_002385151.1 4238220 D 585054 CDS YP_002385152.1 218551360 7121873 4239350..4239592 1 NC_011740.1 coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia; phage shock protein G 4239592 pspG 7121873 pspG Escherichia fergusonii ATCC 35469 phage shock protein G YP_002385152.1 4239350 D 585054 CDS YP_002385153.1 218551361 7121874 complement(4239767..4240750) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94089392, 7602590; Product type e : enzyme; quinone oxidoreductase 4240750 qor 7121874 qor Escherichia fergusonii ATCC 35469 quinone oxidoreductase YP_002385153.1 4239767 R 585054 CDS YP_002385154.1 218551362 7122339 4241253..4242668 1 NC_011740.1 unwinds double stranded DNA; replicative DNA helicase 4242668 dnaB 7122339 dnaB Escherichia fergusonii ATCC 35469 replicative DNA helicase YP_002385154.1 4241253 D 585054 CDS YP_002385155.1 218551363 7122908 complement(4242701..4243321) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4243321 7122908 EFER_4142 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385155.1 4242701 R 585054 CDS YP_002385156.1 218551364 7123257 4243388..4244467 1 NC_011740.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 4244467 alr 7123257 alr Escherichia fergusonii ATCC 35469 alanine racemase YP_002385156.1 4243388 D 585054 CDS YP_002385157.1 218551365 7122293 4244490..4245044 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter 4245044 7122293 EFER_4144 Escherichia fergusonii ATCC 35469 transporter YP_002385157.1 4244490 D 585054 CDS YP_002385158.1 218551366 7121022 4245020..4246054 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator 4246054 7121022 EFER_4145 Escherichia fergusonii ATCC 35469 transcriptional regulator YP_002385158.1 4245020 D 585054 CDS YP_002385159.1 218551367 7121023 4246130..4247323 1 NC_011740.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 4247323 tyrB 7121023 tyrB Escherichia fergusonii ATCC 35469 aromatic amino acid aminotransferase YP_002385159.1 4246130 D 585054 CDS YP_002385160.1 218551368 7121953 4250268..4251422 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 10739245, 6376124; Product type e : enzyme; dihydrolipoamide succinyltransferase (E2 component) 4251422 sucB 7121953 sucB Escherichia fergusonii ATCC 35469 dihydrolipoamide succinyltransferase (E2 component) YP_002385160.1 4250268 D 585054 CDS YP_002385161.1 218551369 7121954 4251434..4252852 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; dihydrolipoyl dehydrogenase, E3 component (lpd-like) 4252852 7121954 EFER_4150 Escherichia fergusonii ATCC 35469 dihydrolipoyl dehydrogenase, E3 component (lpd-like) YP_002385161.1 4251434 D 585054 CDS YP_002385162.1 218551370 7123793 4252874..4254043 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type e : enzyme; succinyl-CoA synthetase subunit beta 4254043 sucC 7123793 sucC Escherichia fergusonii ATCC 35469 succinyl-CoA synthetase subunit beta YP_002385162.1 4252874 D 585054 CDS YP_002385163.1 218551371 7121956 4254056..4254928 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; Product type e : enzyme; succinyl-CoA synthetase subunit alpha 4254928 sucD 7121956 sucD Escherichia fergusonii ATCC 35469 succinyl-CoA synthetase subunit alpha YP_002385163.1 4254056 D 585054 CDS YP_002385164.1 218551372 7121958 4255134..4256639 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter membrane protein 4256639 7121958 EFER_4153 Escherichia fergusonii ATCC 35469 transporter membrane protein YP_002385164.1 4255134 D 585054 CDS YP_002385165.1 218551373 7121024 4256513..4257724 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; malate/L-lactate dehydrogenases 4257724 7121024 EFER_4154 Escherichia fergusonii ATCC 35469 malate/L-lactate dehydrogenases YP_002385165.1 4256513 D 585054 CDS YP_002385166.1 218551374 7121025 complement(4257713..4259071) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 3671068; Product type r : regulator; C4-dicarboxylate transport transcriptional regulator 4259071 dctD 7121025 dctD Escherichia fergusonii ATCC 35469 C4-dicarboxylate transport transcriptional regulator YP_002385166.1 4257713 R 585054 CDS YP_002385167.1 218551375 7122874 complement(4259061..4260884) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2134335; Product type prc : receptor; C4-dicarboxylate transport sensor protein 4260884 7122874 EFER_4156 Escherichia fergusonii ATCC 35469 C4-dicarboxylate transport sensor protein YP_002385167.1 4259061 R 585054 CDS YP_002385168.1 218551376 7123794 4261161..4261874 1 NC_011740.1 Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase 4261874 aphA 7123794 aphA Escherichia fergusonii ATCC 35469 acid phosphatase/phosphotransferase YP_002385168.1 4261161 D 585054 CDS YP_002385169.1 218551377 7120522 4261985..4262401 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11972052; hypothetical protein 4262401 yjbQ 7120522 yjbQ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385169.1 4261985 D 585054 CDS YP_002385170.1 218551378 7123940 4262405..4262761 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4262761 yjbR 7123940 yjbR Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385170.1 4262405 D 585054 CDS YP_002385171.1 218551379 7121875 complement(4262796..4265618) 1 NC_011740.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 4265618 uvrA 7121875 uvrA Escherichia fergusonii ATCC 35469 excinuclease ABC subunit A YP_002385171.1 4262796 R 585054 CDS YP_002385172.1 218551380 7122645 4265872..4266408 1 NC_011740.1 binds to single stranded DNA and PriA helcase facilitate replication restart; single-stranded DNA-binding protein 4266408 ssb 7122645 ssb Escherichia fergusonii ATCC 35469 single-stranded DNA-binding protein YP_002385172.1 4265872 D 585054 CDS YP_002385173.1 218551381 7121942 complement(4266507..4266839) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 4266839 yjcB 7121942 yjcB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385173.1 4266507 R 585054 CDS YP_002385174.1 218551382 7123389 complement(4267032..4267355) 1 NC_011740.1 regulates genes involved in response to oxidative stress; DNA-binding transcriptional regulator SoxS 4267355 soxS 7123389 soxS Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator SoxS YP_002385174.1 4267032 R 585054 CDS YP_002385175.1 218551383 7121801 4267442..4267906 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91210176, 91360349, 94139656, 9564045, 10207625, 12670967, 1653416, 1708380, 7673113, 8065907, 8306957, 8631739, 8969171, 9019397, 9092651, 9204707; Product type r : regulator; DNA-binding transcriptional dual regulator 4267906 soxR 7121801 soxR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional dual regulator YP_002385175.1 4267442 D 585054 CDS YP_002385176.1 218551384 7121185 4268485..4269834 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; permease 4269834 yjcD 7121185 yjcD Escherichia fergusonii ATCC 35469 permease YP_002385176.1 4268485 D 585054 CDS YP_002385177.1 218551385 7121876 4269991..4271637 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 21557160, 11479290; Product type pt : transporter; cation/proton antiporter 4271637 yjcE 7121876 yjcE Escherichia fergusonii ATCC 35469 cation/proton antiporter YP_002385177.1 4269991 D 585054 CDS YP_002385178.1 218551386 7122000 complement(4271701..4272036) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 93328121, 9650256, 2155230; hypothetical protein 4272036 phnA 7122000 phnA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385178.1 4271701 R 585054 CDS YP_002385179.1 218551387 7122596 4272450..4274750 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4274750 7122596 EFER_4168 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385179.1 4272450 D 585054 CDS YP_002385180.1 218551388 7121026 4274740..4275582 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4275582 7121026 EFER_4169 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385180.1 4274740 D 585054 CDS YP_002385181.1 218551389 7121027 4275863..4277365 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10049386, 12525168, 92165733, 93132799, 9871325, 99376621, 8421314; Product type t : transporter; proline/glycine betaine transporter 4277365 proP 7121027 proP Escherichia fergusonii ATCC 35469 proline/glycine betaine transporter YP_002385181.1 4275863 D 585054 CDS YP_002385182.1 218551390 7120134 complement(4277470..4278612) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94110256, 8282725; Product type r : regulator; sensor protein BasS/PmrB 4278612 basS 7120134 basS Escherichia fergusonii ATCC 35469 sensor protein BasS/PmrB YP_002385182.1 4277470 R 585054 CDS YP_002385183.1 218551391 7121645 complement(4278609..4279298) 1 NC_011740.1 response regulator in two-component regulatory system with BasS; DNA-binding transcriptional regulator BasR 4279298 basR 7121645 basR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator BasR YP_002385183.1 4278609 R 585054 CDS YP_002385184.1 218551392 7123356 complement(4279277..4280920) 1 NC_011740.1 with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division; cell division protein 4280920 eptA 7123356 eptA Escherichia fergusonii ATCC 35469 cell division protein YP_002385184.1 4279277 R 585054 CDS YP_002385185.1 218551393 7122959 complement(4281025..4281915) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : c; Product type r : regulator; DNA-binding transcriptional activator 4281915 adiY 7122959 adiY Escherichia fergusonii ATCC 35469 DNA-binding transcriptional activator YP_002385185.1 4281025 R 585054 CDS YP_002385186.1 218551394 7122276 complement(4282321..4282947) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 4282947 yjdF 7122276 yjdF Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385186.1 4282321 R 585054 CDS YP_002385187.1 218551395 7123962 complement(4283070..4284716) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86142617, 88193096, 89255123, 2656658; Product type e : enzyme; anaerobic class I fumarate hydratase 4284716 fumB 7123962 fumB Escherichia fergusonii ATCC 35469 anaerobic class I fumarate hydratase YP_002385187.1 4283070 R 585054 CDS YP_002385188.1 218551396 7120154 complement(4284794..4286134) 1 NC_011740.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter 4286134 dcuB 7120154 dcuB Escherichia fergusonii ATCC 35469 anaerobic C4-dicarboxylate transporter YP_002385188.1 4284794 R 585054 CDS YP_002385189.1 218551397 7124118 complement(4286696..4287418) 1 NC_011740.1 response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration; DNA-binding transcriptional activator DcuR 4287418 dcuR 7124118 dcuR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional activator DcuR YP_002385189.1 4286696 R 585054 CDS YP_002385190.1 218551398 7122878 complement(4287415..4289046) 1 NC_011740.1 C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; sensory histidine kinase DcuS 4289046 dcuS 7122878 dcuS Escherichia fergusonii ATCC 35469 sensory histidine kinase DcuS YP_002385190.1 4287415 R 585054 CDS YP_002385191.1 218551399 7122879 complement(4289081..4289230) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4289230 7122879 EFER_4180 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385191.1 4289081 R 585054 CDS YP_002385192.1 218551400 7123795 4289538..4291964 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; anaerobic dimethyl sulfoxide reductase subunit A 4291964 dmsA 7123795 dmsA Escherichia fergusonii ATCC 35469 anaerobic dimethyl sulfoxide reductase subunit A YP_002385192.1 4289538 D 585054 CDS YP_002385193.1 218551401 7123553 4291978..4292604 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14522592; Product type pc : carrier; anaerobic reductase subunit B 4292604 7123553 EFER_4182 Escherichia fergusonii ATCC 35469 anaerobic reductase subunit B YP_002385193.1 4291978 D 585054 CDS YP_002385194.1 218551402 7121028 4292597..4293373 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14522592; Product type pe : enzyme; anaerobic reductase subunit C 4293373 7121028 EFER_4183 Escherichia fergusonii ATCC 35469 anaerobic reductase subunit C YP_002385194.1 4292597 D 585054 CDS YP_002385195.1 218551403 7121029 4293377..4294024 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14522592, 11309116; Product type pf : factor; twin-argninine leader-binding protein for anaerobic dehydrogenase 4294024 7121029 EFER_4184 Escherichia fergusonii ATCC 35469 twin-argninine leader-binding protein for anaerobic dehydrogenase YP_002385195.1 4293377 D 585054 CDS YP_002385196.1 218551404 7121030 4293877..4294551 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; ferredoxin 4294551 7121030 EFER_4185 Escherichia fergusonii ATCC 35469 ferredoxin YP_002385196.1 4293877 D 585054 CDS YP_002385197.1 218551405 7120051 complement(4295656..4296231) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1370290; Product type pr : regulator; transcriptional regulator 4296231 yjdC 7120051 yjdC Escherichia fergusonii ATCC 35469 transcriptional regulator YP_002385197.1 4295656 R 585054 CDS YP_002385198.1 218551406 7123961 complement(4296268..4297962) 1 NC_011740.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein 4297962 dipZ 7123961 dipZ Escherichia fergusonii ATCC 35469 thiol:disulfide interchange protein YP_002385198.1 4296268 R 585054 CDS YP_002385199.1 218551407 7123552 complement(4297938..4298282) 1 NC_011740.1 copper binding protein required for copper tolerance; involved in resistance toward heavy metals; divalent-cation tolerance protein CutA 4298282 cutA 7123552 cutA Escherichia fergusonii ATCC 35469 divalent-cation tolerance protein CutA YP_002385199.1 4297938 R 585054 CDS YP_002385200.1 218551408 7122832 complement(4298392..4299693) 1 NC_011740.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter 4299693 dcuA 7122832 dcuA Escherichia fergusonii ATCC 35469 anaerobic C4-dicarboxylate transporter YP_002385200.1 4298392 R 585054 CDS YP_002385201.1 218551409 7124117 complement(4299807..4301243) 1 NC_011740.1 catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 4301243 aspA 7124117 aspA Escherichia fergusonii ATCC 35469 aspartate ammonia-lyase YP_002385201.1 4299807 R 585054 CDS YP_002385202.1 218551410 7120570 4301580..4302056 1 NC_011740.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA protein 4302056 fxsA 7120570 fxsA Escherichia fergusonii ATCC 35469 FxsA protein YP_002385202.1 4301580 D 585054 CDS YP_002385203.1 218551411 7120157 complement(4302072..4303328) 1 NC_011740.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function; inner membrane protein YjeH 4303328 yjeH 7120157 yjeH Escherichia fergusonii ATCC 35469 inner membrane protein YjeH YP_002385203.1 4302072 R 585054 CDS YP_002385204.1 218551412 7122008 4303604..4303897 1 NC_011740.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 4303897 groES 7122008 groES Escherichia fergusonii ATCC 35469 co-chaperonin GroES YP_002385204.1 4303604 D 585054 CDS YP_002385205.1 218551413 7120616 4303941..4305587 1 NC_011740.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 4305587 groEL 7120616 groEL Escherichia fergusonii ATCC 35469 chaperonin GroEL YP_002385205.1 4303941 D 585054 CDS YP_002385206.1 218551414 7120615 4305722..4306075 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4306075 yjeI 7120615 yjeI Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385206.1 4305722 D 585054 CDS YP_002385207.1 218551415 7122009 complement(4306129..4306995) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4306995 7122009 EFER_4197 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385207.1 4306129 R 585054 CDS YP_002385208.1 218551416 7121032 complement(4307370..4308398) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2019591, 10629195; Product type pe : enzyme; lysine aminomutase 4308398 yjeK 7121032 yjeK Escherichia fergusonii ATCC 35469 lysine aminomutase YP_002385208.1 4307370 R 585054 CDS YP_002385209.1 218551417 7122010 4308440..4309006 1 NC_011740.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 4309006 efp 7122010 efp Escherichia fergusonii ATCC 35469 elongation factor P YP_002385209.1 4308440 D 585054 CDS YP_002385210.1 218551418 7122940 4309058..4309183 1 NC_011740.1 acts as and antidote to the bacteriolytic entericidin B in the EcnAB toxin-antitoxin complex; entericidin A 4309183 ecnA 7122940 ecnA Escherichia fergusonii ATCC 35469 entericidin A YP_002385210.1 4309058 D 585054 CDS YP_002385211.1 218551419 7123558 4309294..4309440 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98344100, 9677290; Product type lp : lipoprotein; entericidin B membrane lipoprotein 4309440 ecnB 7123558 ecnB Escherichia fergusonii ATCC 35469 entericidin B membrane lipoprotein YP_002385211.1 4309294 D 585054 CDS YP_002385212.1 218551420 7122934 4309466..4309933 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 11948170; Product type t : transporter; large cation (quaternary ammonium) efflux transporter 4309933 sugE 7122934 sugE Escherichia fergusonii ATCC 35469 large cation (quaternary ammonium) efflux transporter YP_002385212.1 4309466 D 585054 CDS YP_002385213.1 218551421 7121964 complement(4309930..4310463) 1 NC_011740.1 lipocalin; globomycin-sensitive outer membrane lipoprotein; outer membrane lipoprotein Blc 4310463 blc 7121964 blc Escherichia fergusonii ATCC 35469 outer membrane lipoprotein Blc YP_002385213.1 4309930 R 585054 CDS YP_002385214.1 218551422 7121675 complement(4310552..4311685) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92212899, 97464439, 99421326, 10595535, 6795623, 7041115, 9819201; Product type e : enzyme; beta-lactamase 4311685 ampC 7121675 ampC Escherichia fergusonii ATCC 35469 beta-lactamase YP_002385214.1 4310552 R 585054 CDS YP_002385215.1 218551423 7122791 complement(4311748..4312107) 1 NC_011740.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D 4312107 frdD 7122791 frdD Escherichia fergusonii ATCC 35469 fumarate reductase subunit D YP_002385215.1 4311748 R 585054 CDS YP_002385216.1 218551424 7123011 complement(4312118..4312513) 1 NC_011740.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C 4312513 frdC 7123011 frdC Escherichia fergusonii ATCC 35469 fumarate reductase subunit C YP_002385216.1 4312118 R 585054 CDS YP_002385217.1 218551425 7123010 complement(4312524..4313258) 1 NC_011740.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit 4313258 frdB 7123010 frdB Escherichia fergusonii ATCC 35469 fumarate reductase iron-sulfur subunit YP_002385217.1 4312524 R 585054 CDS YP_002385218.1 218551426 7123009 complement(4313251..4315059) 1 NC_011740.1 part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit 4315059 frdA 7123009 frdA Escherichia fergusonii ATCC 35469 fumarate reductase flavoprotein subunit YP_002385218.1 4313251 R 585054 CDS YP_002385219.1 218551427 7124141 4315385..4316362 1 NC_011740.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 4316362 poxA 7124141 poxA Escherichia fergusonii ATCC 35469 lysyl-tRNA synthetase YP_002385219.1 4315385 D 585054 CDS YP_002385220.1 218551428 7123105 4316580..4318082 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter 4318082 yjeM 7123105 yjeM Escherichia fergusonii ATCC 35469 transporter YP_002385220.1 4316580 D 585054 CDS YP_002385221.1 218551429 7123963 4317980..4318183 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4318183 7123963 EFER_4211 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385221.1 4317980 D 585054 CDS YP_002385222.1 218551430 7121033 4318180..4318494 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 4318494 yjeO 7121033 yjeO Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385222.1 4318180 D 585054 CDS YP_002385223.1 218551431 7122011 complement(4318525..4321848) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; hypothetical protein 4321848 yjeP 7122011 yjeP Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385223.1 4318525 R 585054 CDS YP_002385224.1 218551432 7123409 complement(4321870..4322838) 1 NC_011740.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase 4322838 psd 7123409 psd Escherichia fergusonii ATCC 35469 phosphatidylserine decarboxylase YP_002385224.1 4321870 R 585054 CDS YP_002385225.1 218551433 7124017 complement(4322935..4323987) 1 NC_011740.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase 4323987 rsgA 7124017 rsgA Escherichia fergusonii ATCC 35469 ribosome-associated GTPase YP_002385225.1 4322935 R 585054 CDS YP_002385226.1 218551434 7121148 4324082..4324627 1 NC_011740.1 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 4324627 orn 7121148 orn Escherichia fergusonii ATCC 35469 oligoribonuclease YP_002385226.1 4324082 D 585054 CDS YP_002385227.1 218551435 7123579 complement(4324667..4325482) 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type f : factor; arginine-binding periplasmic protein 2 4325482 artJ 7123579 artJ Escherichia fergusonii ATCC 35469 arginine-binding periplasmic protein 2 YP_002385227.1 4324667 R 585054 CDS YP_002385228.1 218551436 7120048 complement(4326260..4327399) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; Fe-S electron transport protein 4327399 yjeS 7120048 yjeS Escherichia fergusonii ATCC 35469 Fe-S electron transport protein YP_002385228.1 4326260 R 585054 CDS YP_002385229.1 218551437 7123964 4327398..4328945 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 4328945 yjeF 7123964 yjeF Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385229.1 4327398 D 585054 CDS YP_002385230.1 218551438 7122007 4328917..4329378 1 NC_011740.1 possibly involved in cell wall synthesis; ATPase 4329378 yjeE 7122007 yjeE Escherichia fergusonii ATCC 35469 ATPase YP_002385230.1 4328917 D 585054 CDS YP_002385231.1 218551439 7122006 4329397..4330734 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21348478, 87242501, 1594459, 7511774; Product type e : enzyme; N-acetylmuramoyl-l-alanine amidase II 4330734 amiB 7122006 amiB Escherichia fergusonii ATCC 35469 N-acetylmuramoyl-l-alanine amidase II YP_002385231.1 4329397 D 585054 CDS YP_002385232.1 218551440 7122300 4330744..4332591 1 NC_011740.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 4332591 mutL 7122300 mutL Escherichia fergusonii ATCC 35469 DNA mismatch repair protein YP_002385232.1 4330744 D 585054 CDS YP_002385233.1 218551441 7120653 4332584..4333534 1 NC_011740.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 4333534 miaA 7120653 miaA Escherichia fergusonii ATCC 35469 tRNA delta(2)-isopentenylpyrophosphate transferase YP_002385233.1 4332584 D 585054 CDS YP_002385234.1 218551442 7120929 4333620..4333928 1 NC_011740.1 Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 4333928 hfq 7120929 hfq Escherichia fergusonii ATCC 35469 RNA-binding protein Hfq YP_002385234.1 4333620 D 585054 CDS YP_002385235.1 218551443 7122192 4334004..4335284 1 NC_011740.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein; GTPase HflX 4335284 hflX 7122192 hflX Escherichia fergusonii ATCC 35469 GTPase HflX YP_002385235.1 4334004 D 585054 CDS YP_002385236.1 218551444 7122191 4335370..4336629 1 NC_011740.1 with HflC inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflK 4336629 hflK 7122191 hflK Escherichia fergusonii ATCC 35469 FtsH protease regulator HflK YP_002385236.1 4335370 D 585054 CDS YP_002385237.1 218551445 7122190 4336632..4337636 1 NC_011740.1 with HflK inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflC 4337636 hflC 7122190 hflC Escherichia fergusonii ATCC 35469 FtsH protease regulator HflC YP_002385237.1 4336632 D 585054 CDS YP_002385238.1 218551446 7122188 4337718..4337915 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 4337915 yjeT 7122188 yjeT Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385238.1 4337718 D 585054 CDS YP_002385239.1 218551447 7122012 4338019..4339317 1 NC_011740.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 4339317 purA 7122012 purA Escherichia fergusonii ATCC 35469 adenylosuccinate synthetase YP_002385239.1 4338019 D 585054 CDS YP_002385240.1 218551448 7122318 4339522..4339947 1 NC_011740.1 negatively regulates the transcription of genes upregulated by nitrosative stress; transcriptional repressor NsrR 4339947 nsrR 7122318 nsrR Escherichia fergusonii ATCC 35469 transcriptional repressor NsrR YP_002385240.1 4339522 D 585054 CDS YP_002385241.1 218551449 7119665 4339986..4342427 1 NC_011740.1 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs; exoribonuclease R 4342427 rnr 7119665 rnr Escherichia fergusonii ATCC 35469 exoribonuclease R YP_002385241.1 4339986 D 585054 CDS YP_002385242.1 218551450 7121431 4342518..4343249 1 NC_011740.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 4343249 rlmB 7121431 rlmB Escherichia fergusonii ATCC 35469 23S rRNA (guanosine-2'-O-)-methyltransferase YP_002385242.1 4342518 D 585054 CDS YP_002385243.1 218551451 7123865 4343376..4343771 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4343771 yjfI 7123865 yjfI Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385243.1 4343376 D 585054 CDS YP_002385244.1 218551452 7122014 4343790..4344488 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator effector protein 4344488 yjfJ 7122014 yjfJ Escherichia fergusonii ATCC 35469 transcriptional regulator effector protein YP_002385244.1 4343790 D 585054 CDS YP_002385245.1 218551453 7122015 4344654..4345313 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4345313 yjfK 7122015 yjfK Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385245.1 4344654 D 585054 CDS YP_002385246.1 218551454 7122016 4345331..4345729 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 4345729 yjfL 7122016 yjfL Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385246.1 4345331 D 585054 CDS YP_002385247.1 218551455 7122017 4345733..4346386 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4346386 7122017 EFER_4238 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385247.1 4345733 D 585054 CDS YP_002385248.1 218551456 7121034 4346389..4347552 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; synthetase/amidase 4347552 yjfC 7121034 yjfC Escherichia fergusonii ATCC 35469 synthetase/amidase YP_002385248.1 4346389 D 585054 CDS YP_002385249.1 218551457 7123410 4347618..4349261 1 NC_011740.1 catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA; isovaleryl CoA dehydrogenase 4349261 aidB 7123410 aidB Escherichia fergusonii ATCC 35469 isovaleryl CoA dehydrogenase YP_002385249.1 4347618 D 585054 CDS YP_002385250.1 218551458 7122289 complement(4349404..4349724) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4349724 yjfN 7122289 yjfN Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385250.1 4349404 R 585054 CDS YP_002385251.1 218551459 7122018 complement(4349908..4350279) 1 NC_011740.1 in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility; biofilm stress and motility protein A 4350279 yjfO 7122018 yjfO Escherichia fergusonii ATCC 35469 biofilm stress and motility protein A YP_002385251.1 4349908 R 585054 CDS YP_002385252.1 218551460 7123965 4350463..4351212 1 NC_011740.1 YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo; esterase 4351212 7123965 EFER_4243 Escherichia fergusonii ATCC 35469 esterase YP_002385252.1 4350463 D 585054 CDS YP_002385253.1 218551461 7121035 complement(4351209..4351964) 1 NC_011740.1 negative regulator of ulaG and ulaABCDEF; transcriptional repressor UlaR 4351964 ulaR 7121035 ulaR Escherichia fergusonii ATCC 35469 transcriptional repressor UlaR YP_002385253.1 4351209 R 585054 CDS YP_002385254.1 218551462 7124076 complement(4352072..4353136) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12644495, 15808744; Product type pe : enzyme; L-ascorbate 6-phosphate lactonase 4353136 ulaG 7124076 ulaG Escherichia fergusonii ATCC 35469 L-ascorbate 6-phosphate lactonase YP_002385254.1 4352072 R 585054 CDS YP_002385255.1 218551463 7122636 4353488..4354885 1 NC_011740.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 4354885 ulaA 7122636 ulaA Escherichia fergusonii ATCC 35469 PTS system ascorbate-specific transporter subunit IIC YP_002385255.1 4353488 D 585054 CDS YP_002385256.1 218551464 7122631 4354901..4355206 1 NC_011740.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIB 4355206 ulaB 7122631 ulaB Escherichia fergusonii ATCC 35469 PTS system L-ascorbate-specific transporter subunit IIB YP_002385256.1 4354901 D 585054 CDS YP_002385257.1 218551465 7122632 4355216..4355680 1 NC_011740.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIA 4355680 ulaC 7122632 ulaC Escherichia fergusonii ATCC 35469 PTS system L-ascorbate-specific transporter subunit IIA YP_002385257.1 4355216 D 585054 CDS YP_002385258.1 218551466 7122633 4355694..4356344 1 NC_011740.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 4356344 ulaD 7122633 ulaD Escherichia fergusonii ATCC 35469 3-keto-L-gulonate-6-phosphate decarboxylase YP_002385258.1 4355694 D 585054 CDS YP_002385259.1 218551467 7122634 4356354..4357208 1 NC_011740.1 UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway; L-xylulose 5-phosphate 3-epimerase 4357208 ulaE 7122634 ulaE Escherichia fergusonii ATCC 35469 L-xylulose 5-phosphate 3-epimerase YP_002385259.1 4356354 D 585054 CDS YP_002385260.1 218551468 7124075 4357208..4357894 1 NC_011740.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 4357894 sgaE 7124075 sgaE Escherichia fergusonii ATCC 35469 L-ribulose-5-phosphate 4-epimerase YP_002385260.1 4357208 D 585054 CDS YP_002385261.1 218551469 7122635 complement(4358023..4358298) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4358298 yjfY 7122635 yjfY Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385261.1 4358023 R 585054 CDS YP_002385262.1 218551470 7122019 4358626..4359021 1 NC_011740.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 4359021 rpsF 7122019 rpsF Escherichia fergusonii ATCC 35469 30S ribosomal protein S6 YP_002385262.1 4358626 D 585054 CDS YP_002385263.1 218551471 7121131 4359028..4359342 1 NC_011740.1 binds single-stranded DNA at the primosome assembly site; primosomal replication protein N 4359342 priB 7121131 priB Escherichia fergusonii ATCC 35469 primosomal replication protein N YP_002385263.1 4359028 D 585054 CDS YP_002385264.1 218551472 7120126 4359347..4359574 1 NC_011740.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 4359574 rpsR 7120126 rpsR Escherichia fergusonii ATCC 35469 30S ribosomal protein S18 YP_002385264.1 4359347 D 585054 CDS YP_002385265.1 218551473 7123814 4359616..4360065 1 NC_011740.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 4360065 rplI 7123814 rplI Escherichia fergusonii ATCC 35469 50S ribosomal protein L9 YP_002385265.1 4359616 D 585054 CDS YP_002385266.1 218551474 7123266 complement(4360177..4361148) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; dicarboxylate-binding periplasmic protein 4361148 7123266 EFER_4257 Escherichia fergusonii ATCC 35469 dicarboxylate-binding periplasmic protein YP_002385266.1 4360177 R 585054 CDS YP_002385267.1 218551475 7121036 complement(4361201..4362502) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ATP-independent transporter subunit 4362502 7121036 EFER_4258 Escherichia fergusonii ATCC 35469 ATP-independent transporter subunit YP_002385267.1 4361201 R 585054 CDS YP_002385268.1 218551476 7121037 complement(4362545..4363045) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ATP-independent transporter subunit 4363045 7121037 EFER_4259 Escherichia fergusonii ATCC 35469 ATP-independent transporter subunit YP_002385268.1 4362545 R 585054 CDS YP_002385269.1 218551477 7121038 complement(4363042..4365123) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; oxidoreductase 4365123 7121038 EFER_4260 Escherichia fergusonii ATCC 35469 oxidoreductase YP_002385269.1 4363042 R 585054 CDS YP_002385270.1 218551478 7120451 complement(4365120..4366661) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; CoA transferase 4366661 7120451 EFER_4261 Escherichia fergusonii ATCC 35469 CoA transferase YP_002385270.1 4365120 R 585054 CDS YP_002385271.1 218551479 7120453 complement(4366671..4367447) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; acyl-CoA hydratase 4367447 7120453 EFER_4262 Escherichia fergusonii ATCC 35469 acyl-CoA hydratase YP_002385271.1 4366671 R 585054 CDS YP_002385272.1 218551480 7123162 complement(4367457..4368299) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 4368299 7123162 EFER_4263 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385272.1 4367457 R 585054 CDS YP_002385273.1 218551481 7123703 complement(4368309..4369100) 1 NC_011740.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 4369100 7123703 EFER_4264 Escherichia fergusonii ATCC 35469 3-ketoacyl-ACP reductase YP_002385273.1 4368309 R 585054 CDS YP_002385274.1 218551482 7120454 4369223..4369948 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator 4369948 ytfA 7120454 ytfA Escherichia fergusonii ATCC 35469 transcriptional regulator YP_002385274.1 4369223 D 585054 CDS YP_002385275.1 218551483 7123589 complement(4369949..4370611) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8559074; Product type ps : structure; cell envelope opacity-associated protein 4370611 ytfB 7123589 ytfB Escherichia fergusonii ATCC 35469 cell envelope opacity-associated protein YP_002385275.1 4369949 R 585054 CDS YP_002385276.1 218551484 7119758 4370797..4371417 1 NC_011740.1 FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; peptidyl-prolyl cis-trans isomerase 4371417 fklB 7119758 fklB Escherichia fergusonii ATCC 35469 peptidyl-prolyl cis-trans isomerase YP_002385276.1 4370797 D 585054 CDS YP_002385277.1 218551485 7120023 4371725..4373137 1 NC_011740.1 involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine; D-alanine/D-serine/glycine permease 4373137 cycA 7120023 cycA Escherichia fergusonii ATCC 35469 D-alanine/D-serine/glycine permease YP_002385277.1 4371725 D 585054 CDS YP_002385278.1 218551486 7123541 complement(4373182..4373844) 1 NC_011740.1 Involved in anaerobic NO protection and iron metabolism; iron-sulfur cluster repair di-iron protein 4373844 ytfE 7123541 ytfE Escherichia fergusonii ATCC 35469 iron-sulfur cluster repair di-iron protein YP_002385278.1 4373182 R 585054 CDS YP_002385279.1 218551487 7119759 complement(4373952..4374926) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 4374926 ytfF 7119759 ytfF Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385279.1 4373952 R 585054 CDS YP_002385280.1 218551488 7119760 complement(4375026..4375886) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14747727; Product type e : enzyme; NAD(P)H:quinone oxidoreductase 4375886 ytfG 7119760 ytfG Escherichia fergusonii ATCC 35469 NAD(P)H:quinone oxidoreductase YP_002385280.1 4375026 R 585054 CDS YP_002385281.1 218551489 7119761 4375975..4376355 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 20088838; Product type pr : regulator; transcriptional regulator 4376355 ytfH 7119761 ytfH Escherichia fergusonii ATCC 35469 transcriptional regulator YP_002385281.1 4375975 D 585054 CDS YP_002385282.1 218551490 7123045 complement(4376484..4378427) 1 NC_011740.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein 4378427 cpdB 7123045 cpdB Escherichia fergusonii ATCC 35469 bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein YP_002385282.1 4376484 R 585054 CDS YP_002385283.1 218551491 7122795 4378616..4379356 1 NC_011740.1 catalyzes the formation of AMP from adenosine-3',5'-bisphosphate; adenosine-3'(2'),5'-bisphosphate nucleotidase 4379356 cysQ 7122795 cysQ Escherichia fergusonii ATCC 35469 adenosine-3'(2'),5'-bisphosphate nucleotidase YP_002385283.1 4378616 D 585054 CDS YP_002385284.1 218551492 7122855 complement(4379346..4379903) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9298646; Product type pr : regulator; transcriptional regulator 4379903 ytfJ 7122855 ytfJ Escherichia fergusonii ATCC 35469 transcriptional regulator YP_002385284.1 4379346 R 585054 CDS YP_002385285.1 218551493 7123590 4380228..4380434 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4380434 ytfK 7123590 ytfK Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385285.1 4380228 D 585054 CDS YP_002385286.1 218551494 7119762 complement(4380495..4381838) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 4381838 ytfL 7119762 ytfL Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385286.1 4380495 R 585054 CDS YP_002385287.1 218551495 7123046 4382091..4382501 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 4382501 7123046 EFER_4278 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385287.1 4382091 D 585054 CDS YP_002385288.1 218551496 7120455 complement(4382581..4382910) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4382910 7120455 EFER_4279 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385288.1 4382581 R 585054 CDS YP_002385289.1 218551497 7120456 complement(4382978..4383427) 1 NC_011740.1 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 4383427 rpiB 7120456 rpiB Escherichia fergusonii ATCC 35469 ribose-5-phosphate isomerase B YP_002385289.1 4382978 R 585054 CDS YP_002385290.1 218551498 7121436 4383788..4384678 1 NC_011740.1 involved in rpiB and als operon repression; DNA-binding transcriptional repressor RpiR 4384678 rpiR 7121436 rpiR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional repressor RpiR YP_002385290.1 4383788 D 585054 CDS YP_002385291.1 218551499 7121437 4384735..4385670 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20026827, 9401019, 10064713, 8576032; Product type t : transporter; D-allose transporter subunit 4385670 alsB 7121437 alsB Escherichia fergusonii ATCC 35469 D-allose transporter subunit YP_002385291.1 4384735 D 585054 CDS YP_002385292.1 218551500 7122295 4385731..4387263 1 NC_011740.1 with AlsBC acts to import allose into the cell; AlsA contain 2 ATP-binding domains; D-allose transporter ATP-binding protein 4387263 alsA 7122295 alsA Escherichia fergusonii ATCC 35469 D-allose transporter ATP-binding protein YP_002385292.1 4385731 D 585054 CDS YP_002385293.1 218551501 7122294 4387242..4388222 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20026827, 9401019; Product type t : transporter; D-allose transporter subunit 4388222 alsC 7122294 alsC Escherichia fergusonii ATCC 35469 D-allose transporter subunit YP_002385293.1 4387242 D 585054 CDS YP_002385294.1 218551502 7122296 4388233..4388919 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20026827, 9401019; Product type e : enzyme; allulose-6-phosphate 3-epimerase 4388919 alsE 7122296 alsE Escherichia fergusonii ATCC 35469 allulose-6-phosphate 3-epimerase YP_002385294.1 4388233 D 585054 CDS YP_002385295.1 218551503 7122297 4388888..4389826 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9401019; Product type e : enzyme; D-allose kinase 4389826 alsK 7122297 alsK Escherichia fergusonii ATCC 35469 D-allose kinase YP_002385295.1 4388888 D 585054 CDS YP_002385296.1 218551504 7122298 4390054..4392057 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1587481; Product type pe : enzyme; alkyl sulfatase 4392057 yjcS 7122298 yjcS Escherichia fergusonii ATCC 35469 alkyl sulfatase YP_002385296.1 4390054 D 585054 CDS YP_002385297.1 218551505 7122004 4392222..4392539 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4392539 7122004 EFER_4288 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385297.1 4392222 D 585054 CDS YP_002385298.1 218551506 7120457 4392560..4393591 1 NC_011740.1 with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance protein MdtN 4393591 yjcR 7120457 yjcR Escherichia fergusonii ATCC 35469 multidrug resistance protein MdtN YP_002385298.1 4392560 D 585054 CDS YP_002385299.1 218551507 7122003 4393591..4395597 1 NC_011740.1 possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug efflux system protein MdtO 4395597 7122003 EFER_4290 Escherichia fergusonii ATCC 35469 multidrug efflux system protein MdtO YP_002385299.1 4393591 D 585054 CDS YP_002385300.1 218551508 7123704 4395594..4397051 1 NC_011740.1 part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family; outer membrane efflux protein MdtP 4397051 yjcP 7123704 yjcP Escherichia fergusonii ATCC 35469 outer membrane efflux protein MdtP YP_002385300.1 4395594 D 585054 CDS YP_002385301.1 218551509 7122002 4397249..4399396 1 NC_011740.1 Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; formate dehydrogenase-H, selenopolypeptide subunit 4399396 fdhF 7122002 fdhF Escherichia fergusonii ATCC 35469 formate dehydrogenase-H, selenopolypeptide subunit YP_002385301.1 4397249 D 585054 CDS YP_002385302.1 218551510 7123086 4399487..4400176 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4400176 yjcO 7123086 yjcO Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385302.1 4399487 D 585054 CDS YP_002385303.1 218551511 7122001 complement(4400250..4401746) 1 NC_011740.1 carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system; glutamate/aspartate:proton symporter 4401746 gltP 7122001 gltP Escherichia fergusonii ATCC 35469 glutamate/aspartate:proton symporter YP_002385303.1 4400250 R 585054 CDS YP_002385304.1 218551512 7123722 4402212..4404170 1 NC_011740.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 4404170 acs 7123722 acs Escherichia fergusonii ATCC 35469 acetyl-CoA synthetase YP_002385304.1 4402212 D 585054 CDS YP_002385305.1 218551513 7124010 4404231..4404710 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4404710 7124010 EFER_4297 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385305.1 4404231 D 585054 CDS YP_002385306.1 218551514 7120458 4404707..4406356 1 NC_011740.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake; acetate permease 4406356 actP 7120458 actP Escherichia fergusonii ATCC 35469 acetate permease YP_002385306.1 4404707 D 585054 CDS YP_002385307.1 218551515 7124011 complement(4406397..4407035) 1 NC_011740.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 4407035 msrA 7124011 msrA Escherichia fergusonii ATCC 35469 methionine sulfoxide reductase A YP_002385307.1 4406397 R 585054 CDS YP_002385308.1 218551516 7120973 4407241..4408974 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 4408974 ytfM 7120973 ytfM Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385308.1 4407241 D 585054 CDS YP_002385309.1 218551517 7119763 4408971..4412747 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4412747 ytfN 7119763 ytfN Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385309.1 4408971 D 585054 CDS YP_002385310.1 218551518 7119764 4412750..4413091 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4413091 ytfP 7119764 ytfP Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385310.1 4412750 D 585054 CDS YP_002385311.1 218551519 7119765 4413241..4414713 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4414713 7119765 EFER_4303 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385311.1 4413241 D 585054 CDS YP_002385312.1 218551520 7120459 complement(4414786..4416114) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; IS4 transposase; KpLE2 phage-like element 4416114 insG 7120459 insG Escherichia fergusonii ATCC 35469 IS4 transposase; KpLE2 phage-like element YP_002385312.1 4414786 R 585054 CDS YP_002385313.1 218551521 7120746 complement(4416564..4417094) 1 NC_011740.1 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 4417094 ppa 7120746 ppa Escherichia fergusonii ATCC 35469 inorganic pyrophosphatase YP_002385313.1 4416564 R 585054 CDS YP_002385314.1 218551522 7120106 4417404..4418360 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9298646; Product type pt : transporter; sugar ABC transporter periplasmic-binding protein 4418360 ytfQ 7120106 ytfQ Escherichia fergusonii ATCC 35469 sugar ABC transporter periplasmic-binding protein YP_002385314.1 4417404 D 585054 CDS YP_002385315.1 218551523 7119766 4418493..4419995 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; sugar ABC transporter ATP-binding protein 4419995 ytfR 7119766 ytfR Escherichia fergusonii ATCC 35469 sugar ABC transporter ATP-binding protein YP_002385315.1 4418493 D 585054 CDS YP_002385316.1 218551524 7119767 4420009..4421031 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; sugar ABC transporter membrane protein 4421031 ytfT 7119767 ytfT Escherichia fergusonii ATCC 35469 sugar ABC transporter membrane protein YP_002385316.1 4420009 D 585054 CDS YP_002385317.1 218551525 7119768 4421018..4422013 1 NC_011740.1 membrane component of a sugar ABC transporter system; inner membrane ABC transporter permease YjfF 4422013 yjfF 7119768 yjfF Escherichia fergusonii ATCC 35469 inner membrane ABC transporter permease YjfF YP_002385317.1 4421018 D 585054 CDS YP_002385318.1 218551526 7122013 complement(4422046..4423044) 1 NC_011740.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 4423044 fbp 7122013 fbp Escherichia fergusonii ATCC 35469 fructose-1,6-bisphosphatase YP_002385318.1 4422046 R 585054 CDS YP_002385319.1 218551527 7123085 4423220..4424593 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96404780, 2843822, 7984428, 8808921; Product type e : enzyme; UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 4424593 mpl 7123085 mpl Escherichia fergusonii ATCC 35469 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase YP_002385319.1 4423220 D 585054 CDS YP_002385320.1 218551528 7120959 complement(4424676..4425227) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4425227 yjgA 7120959 yjgA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385320.1 4424676 R 585054 CDS YP_002385321.1 218551529 7123411 4425321..4426673 1 NC_011740.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; peptidase PmbA 4426673 pmbA 7123411 pmbA Escherichia fergusonii ATCC 35469 peptidase PmbA YP_002385321.1 4425321 D 585054 CDS YP_002385322.1 218551530 7120090 4426726..4427112 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1761034, 8499452, 10393541; Product type c : carrier; soluble cytochrome b562 4427112 cybC 7120090 cybC Escherichia fergusonii ATCC 35469 soluble cytochrome b562 YP_002385322.1 4426726 D 585054 CDS YP_002385323.1 218551531 7122838 complement(4427109..4427255) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4427255 7122838 EFER_4315 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385323.1 4427109 R 585054 CDS YP_002385324.1 218551532 7123163 4427303..4427545 1 NC_011740.1 Qin prophage; bifunctional antitoxin of the RelE-RelB toxin-antitoxin system/transcriptional repressor; bifunctional antitoxin/transcriptional repressor RelB 4427545 7123163 EFER_4316 Escherichia fergusonii ATCC 35469 bifunctional antitoxin/transcriptional repressor RelB YP_002385324.1 4427303 D 585054 CDS YP_002385325.1 218551533 7120460 4427457..4427831 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9767574, 11274135, 11717402, 12526800, 15576765; Product type f : factor; RelE protein; cytotoxic translational repressor of toxin-antitoxin stability system 4427831 7120460 EFER_4317 Escherichia fergusonii ATCC 35469 RelE protein; cytotoxic translational repressor of toxin-antitoxin stability system YP_002385325.1 4427457 D 585054 CDS YP_002385326.1 218551534 7120461 complement(4427828..4428292) 1 NC_011740.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein 4428292 nrdG 7120461 nrdG Escherichia fergusonii ATCC 35469 anaerobic ribonucleotide reductase-activating protein YP_002385326.1 4427828 R 585054 CDS YP_002385327.1 218551535 7119662 4427945..4428436 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 4428436 7119662 EFER_4319 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385327.1 4427945 D 585054 CDS YP_002385328.1 218551536 7123164 complement(4428450..4430588) 1 NC_011740.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 4430588 nrdD 7123164 nrdD Escherichia fergusonii ATCC 35469 anaerobic ribonucleoside triphosphate reductase YP_002385328.1 4428450 R 585054 CDS YP_002385329.1 218551537 7123027 complement(4430982..4432637) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90264345, 93302496, 8083158, 8421692; Product type e : enzyme; trehalose-6-phosphate hydrolase 4432637 treC 7123027 treC Escherichia fergusonii ATCC 35469 trehalose-6-phosphate hydrolase YP_002385329.1 4430982 R 585054 CDS YP_002385330.1 218551538 7122155 complement(4432688..4434109) 1 NC_011740.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system trehalose(maltose)-specific transporter subunit IIBC 4434109 treB 7122155 treB Escherichia fergusonii ATCC 35469 PTS system trehalose(maltose)-specific transporter subunit IIBC YP_002385330.1 4432688 R 585054 CDS YP_002385331.1 218551539 7122154 complement(4434228..4435175) 1 NC_011740.1 regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon; trehalose repressor 4435175 treR 7122154 treR Escherichia fergusonii ATCC 35469 trehalose repressor YP_002385331.1 4434228 R 585054 CDS YP_002385332.1 218551540 7123433 complement(4435298..4435759) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4435759 7123433 EFER_4324 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385332.1 4435298 R 585054 CDS YP_002385333.1 218551541 7120462 complement(4435819..4436205) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12515541, 10493123, 10595546, 9298646; Product type pe : enzyme; ketoacid-binding protein 4436205 yjgF 7120462 yjgF Escherichia fergusonii ATCC 35469 ketoacid-binding protein YP_002385333.1 4435819 R 585054 CDS YP_002385334.1 218551542 7123412 complement(4436277..4436738) 1 NC_011740.1 involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase regulatory subunit 4436738 pyrI 7123412 pyrI Escherichia fergusonii ATCC 35469 aspartate carbamoyltransferase regulatory subunit YP_002385334.1 4436277 R 585054 CDS YP_002385335.1 218551543 7122338 complement(4436751..4437686) 1 NC_011740.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 4437686 pyrB 7122338 pyrB Escherichia fergusonii ATCC 35469 aspartate carbamoyltransferase catalytic subunit YP_002385335.1 4436751 R 585054 CDS YP_002385336.1 218551544 7122333 complement(4437913..4438452) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; arginine repressor 4438452 7122333 EFER_4328 Escherichia fergusonii ATCC 35469 arginine repressor YP_002385336.1 4437913 R 585054 CDS YP_002385337.1 218551545 7120463 complement(4438527..4439963) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4439963 7120463 EFER_4329 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385337.1 4438527 R 585054 CDS YP_002385338.1 218551546 7120464 complement(4439987..4441018) 1 NC_011740.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 4441018 arcB 7120464 arcB Escherichia fergusonii ATCC 35469 ornithine carbamoyltransferase YP_002385338.1 4439987 R 585054 CDS YP_002385339.1 218551547 7120534 complement(4441015..4441971) 1 NC_011740.1 reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 4441971 arcC 7120534 arcC Escherichia fergusonii ATCC 35469 carbamate kinase YP_002385339.1 4441015 R 585054 CDS YP_002385340.1 218551548 7120535 complement(4441958..4443181) 1 NC_011740.1 catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase 4443181 7120535 EFER_4332 Escherichia fergusonii ATCC 35469 arginine deiminase YP_002385340.1 4441958 R 585054 CDS YP_002385341.1 218551549 7120465 4443855..4444307 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11115104; hypothetical protein 4444307 yjgK 7120465 yjgK Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385341.1 4443855 D 585054 CDS YP_002385342.1 218551550 7122021 complement(4444352..4445374) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90133956, 90153882, 90368679, 3072022, 6369246, 9253409, 9275160, 9298646, 6577418; Product type e : enzyme; ornithine carbamoyltransferase 1 4445374 argI 7122021 argI Escherichia fergusonii ATCC 35469 ornithine carbamoyltransferase 1 YP_002385342.1 4444352 R 585054 CDS YP_002385343.1 218551551 7120540 4445519..4445935 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4445935 yjgD 7120540 yjgD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385343.1 4445519 D 585054 CDS YP_002385344.1 218551552 7122020 complement(4445982..4446497) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; acetyltransferase 4446497 yjgM 7122020 yjgM Escherichia fergusonii ATCC 35469 acetyltransferase YP_002385344.1 4445982 R 585054 CDS YP_002385345.1 218551553 7122022 4446562..4447833 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4447833 7122022 EFER_4338 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385345.1 4446562 D 585054 CDS YP_002385346.1 218551554 7120466 complement(4447892..4450747) 1 NC_011740.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 4450747 valS 7120466 valS Escherichia fergusonii ATCC 35469 valyl-tRNA synthetase YP_002385346.1 4447892 R 585054 CDS YP_002385347.1 218551555 7122656 complement(4450747..4451190) 1 NC_011740.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 4451190 holC 7122656 holC Escherichia fergusonii ATCC 35469 DNA polymerase III subunit chi YP_002385347.1 4450747 R 585054 CDS YP_002385348.1 218551556 7122210 complement(4451256..4451672) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4451672 7122210 EFER_4341 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385348.1 4451256 R 585054 CDS YP_002385349.1 218551557 7123705 complement(4451693..4453204) 1 NC_011740.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 4453204 pepA 7123705 pepA Escherichia fergusonii ATCC 35469 leucyl aminopeptidase YP_002385349.1 4451693 R 585054 CDS YP_002385350.1 218551558 7122574 4453471..4454571 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 4454571 yjgP 7122574 yjgP Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385350.1 4453471 D 585054 CDS YP_002385351.1 218551559 7122023 4454571..4455653 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 4455653 yjgQ 7122023 yjgQ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385351.1 4454571 D 585054 CDS YP_002385352.1 218551560 7122024 complement(4455797..4456372) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11274153; hypothetical protein 4456372 ecfH 7122024 ecfH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385352.1 4455797 R 585054 CDS YP_002385353.1 218551561 7122933 complement(4456382..4456972) 1 NC_011740.1 Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; DnaA initiator-associating protein DiaA 4456972 yraO 7122933 yraO Escherichia fergusonii ATCC 35469 DnaA initiator-associating protein DiaA YP_002385353.1 4456382 R 585054 CDS YP_002385354.1 218551562 7123041 complement(4456992..4457387) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4457387 yraN 7123041 yraN Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385354.1 4456992 R 585054 CDS YP_002385355.1 218551563 7119741 complement(4457345..4459381) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4459381 yraM 7119741 yraM Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385355.1 4457345 R 585054 CDS YP_002385356.1 218551564 7123040 4459446..4460309 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; methyltransferase 4460309 yraL 7123040 yraL Escherichia fergusonii ATCC 35469 methyltransferase YP_002385356.1 4459446 D 585054 CDS YP_002385357.1 218551565 7123039 complement(4460359..4461126) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10931310; Product type e : enzyme; galactosamine-6-phosphate isomerase 4461126 agaI 7123039 agaI Escherichia fergusonii ATCC 35469 galactosamine-6-phosphate isomerase YP_002385357.1 4460359 R 585054 CDS YP_002385358.1 218551566 7124012 complement(4461127..4461918) 1 NC_011740.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IID 4461918 agaD 7124012 agaD Escherichia fergusonii ATCC 35469 PTS system N-acetylgalactosamine-specific transporter subunit IID YP_002385358.1 4461127 R 585054 CDS YP_002385359.1 218551567 7122284 complement(4461908..4462711) 1 NC_011740.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane;protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIC 4462711 agaC 7122284 agaC Escherichia fergusonii ATCC 35469 PTS system N-acetylgalactosamine-specific transporter subunit IIC YP_002385359.1 4461908 R 585054 CDS YP_002385360.1 218551568 7122283 complement(4462750..4463226) 1 NC_011740.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 4463226 agaB 7122283 agaB Escherichia fergusonii ATCC 35469 PTS system N-acetylgalactosamine-specific transporter subunit IIB YP_002385360.1 4462750 R 585054 CDS YP_002385361.1 218551569 7122282 complement(4463392..4464252) 1 NC_011740.1 catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase 4464252 kbaY 7122282 kbaY Escherichia fergusonii ATCC 35469 tagatose-bisphosphate aldolase YP_002385361.1 4463392 R 585054 CDS YP_002385362.1 218551570 7120801 complement(4464265..4465419) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689210, 9697096, 14731281, 8932697; Product type e : enzyme; tagatose-6-phosphate ketose/aldose isomerase 4465419 agaS 7120801 agaS Escherichia fergusonii ATCC 35469 tagatose-6-phosphate ketose/aldose isomerase YP_002385362.1 4464265 R 585054 CDS YP_002385363.1 218551571 7122286 complement(4465770..4466924) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; N-acetylglucosamine-6-phosphate deacetylase 4466924 agaA 7122286 agaA Escherichia fergusonii ATCC 35469 N-acetylglucosamine-6-phosphate deacetylase YP_002385363.1 4465770 R 585054 CDS YP_002385364.1 218551572 7122281 complement(4466900..4467334) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; PTS system N-acetyl-galactosamine / galactosamine transporter subunit IIA 4467334 7122281 EFER_4357 Escherichia fergusonii ATCC 35469 PTS system N-acetyl-galactosamine / galactosamine transporter subunit IIA YP_002385364.1 4466900 R 585054 CDS YP_002385365.1 218551573 7120467 complement(4467352..4468236) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; PTS system hexose/hexosamine family transporter permease IID 4468236 7120467 EFER_4358 Escherichia fergusonii ATCC 35469 PTS system hexose/hexosamine family transporter permease IID YP_002385365.1 4467352 R 585054 CDS YP_002385366.1 218551574 7120468 complement(4468220..4468999) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; PTS system transporter subunit IIC 4468999 7120468 EFER_4359 Escherichia fergusonii ATCC 35469 PTS system transporter subunit IIC YP_002385366.1 4468220 R 585054 CDS YP_002385367.1 218551575 7120469 complement(4469010..4469483) 1 NC_011740.1 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB 4469483 agaV 7120469 agaV Escherichia fergusonii ATCC 35469 PTS system N-acetylgalactosamine-specific transporter subunit IIB YP_002385367.1 4469010 R 585054 CDS YP_002385368.1 218551576 7122287 complement(4469506..4470786) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11976750, 20392444, 10931310, 8932697; Product type e : enzyme; tagatose 6-phosphate aldolase 1, kbaZ subunit 4470786 kbaZ 7122287 kbaZ Escherichia fergusonii ATCC 35469 tagatose 6-phosphate aldolase 1, kbaZ subunit YP_002385368.1 4469506 R 585054 CDS YP_002385369.1 218551577 7123756 4471034..4471843 1 NC_011740.1 transcriptional repressor for the agaZVWA and agaSYBCDI operons; DNA-binding transcriptional regulator AgaR 4471843 agaR 7123756 agaR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator AgaR YP_002385369.1 4471034 D 585054 CDS YP_002385370.1 218551578 7122285 complement(4471898..4472362) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4472362 yhaV 7122285 yhaV Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385370.1 4471898 R 585054 CDS YP_002385371.1 218551579 7119879 complement(4472362..4472697) 1 NC_011740.1 SohA; PrlF; involved in protein secretion; when overproduced or mutated, it induces growth defect and increased export of a reporter protein; a PrlF mutation induces the activity of the Lon protease, and a Lon-deficient strain suppresses the phenotype conferred by the PrlF mutation; regulator PrlF 4472697 sohA 7119879 sohA Escherichia fergusonii ATCC 35469 regulator PrlF YP_002385371.1 4472362 R 585054 CDS YP_002385372.1 218551580 7123377 complement(4472846..4474417) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20225875, 66096392, 81027430, 9772162, 10762278, 2407727; Product type e : enzyme; (D)-galactarate dehydrogenase 4474417 garD 7123377 garD Escherichia fergusonii ATCC 35469 (D)-galactarate dehydrogenase YP_002385372.1 4472846 R 585054 CDS YP_002385373.1 218551581 7123116 4474888..4475658 1 NC_011740.1 cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate; alpha-dehydro-beta-deoxy-D-glucarate aldolase 4475658 garL 7123116 garL Escherichia fergusonii ATCC 35469 alpha-dehydro-beta-deoxy-D-glucarate aldolase YP_002385373.1 4474888 D 585054 CDS YP_002385374.1 218551582 7120174 4475683..4476573 1 NC_011740.1 catalyzes the reduction of tartronate semialdehyde to glycerate; tartronate semialdehyde reductase 4476573 garR 7120174 garR Escherichia fergusonii ATCC 35469 tartronate semialdehyde reductase YP_002385374.1 4475683 D 585054 CDS YP_002385375.1 218551583 7120175 complement(4476668..4476874) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4476874 7120175 EFER_4368 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385375.1 4476668 R 585054 CDS YP_002385376.1 218551584 7121430 complement(4477289..4477990) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15951572, 16411777, 15102328; Product type pe : enzyme; pirin-related protein YhaK 4477990 7121430 EFER_4369 Escherichia fergusonii ATCC 35469 pirin-related protein YhaK YP_002385376.1 4477289 R 585054 CDS YP_002385377.1 218551585 7123165 4478095..4478991 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator 4478991 yhaJ 7123165 yhaJ Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YP_002385377.1 4478095 D 585054 CDS YP_002385378.1 218551586 7119877 complement(4479025..4479414) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 4479414 yhaH 7119877 yhaH Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385378.1 4479025 R 585054 CDS YP_002385379.1 218551587 7119876 complement(4479517..4480503) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 8478329; Product type e : enzyme; S-transferase 4480503 yqjG 7119876 yqjG Escherichia fergusonii ATCC 35469 S-transferase YP_002385379.1 4479517 R 585054 CDS YP_002385380.1 218551588 7119738 complement(4480573..4480965) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; quinol oxidase subunit 4480965 yqjF 7119738 yqjF Escherichia fergusonii ATCC 35469 quinol oxidase subunit YP_002385380.1 4480573 R 585054 CDS YP_002385381.1 218551589 7119737 complement(4481152..4481451) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4481451 yqjK 7119737 yqjK Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385381.1 4481152 R 585054 CDS YP_002385382.1 218551590 7119740 complement(4481441..4481845) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 4481845 yqjE 7119740 yqjE Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385382.1 4481441 R 585054 CDS YP_002385383.1 218551591 7119736 complement(4481848..4482153) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4482153 yqjD 7119736 yqjD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385383.1 4481848 R 585054 CDS YP_002385384.1 218551592 7119735 complement(4482191..4482676) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4482676 7119735 EFER_4377 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385384.1 4482191 R 585054 CDS YP_002385385.1 218551593 7120471 complement(4482707..4483090) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4483090 7120471 EFER_4378 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385385.1 4482707 R 585054 CDS YP_002385386.1 218551594 7120472 complement(4483094..4483756) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 4483756 yqjA 7120472 yqjA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385386.1 4483094 R 585054 CDS YP_002385387.1 218551595 7119734 complement(4483707..4483853) 1 NC_011740.1 Evidence 6 : Doubtful CDS; hypothetical protein 4483853 7119734 EFER_4380 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385387.1 4483707 R 585054 CDS YP_002385388.1 218551596 7120473 complement(4484102..4484878) 1 NC_011740.1 regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization.; DNA-binding transcriptional repressor ExuR 4484878 exuR 7120473 exuR Escherichia fergusonii ATCC 35469 DNA-binding transcriptional repressor ExuR YP_002385388.1 4484102 R 585054 CDS YP_002385389.1 218551597 7119977 complement(4485003..4486313) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 83218546, 98190790; Product type t : transporter; hexuronate transporter 4486313 exuT 7119977 exuT Escherichia fergusonii ATCC 35469 hexuronate transporter YP_002385389.1 4485003 R 585054 CDS YP_002385390.1 218551598 7123083 4486773..4488185 1 NC_011740.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase 4488185 uxaC 7123083 uxaC Escherichia fergusonii ATCC 35469 glucuronate isomerase YP_002385390.1 4486773 D 585054 CDS YP_002385391.1 218551599 7122651 4488200..4489687 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 4570160, 83114543, 3038546; Product type e : enzyme; altronate hydrolase 4489687 uxaA 7122651 uxaA Escherichia fergusonii ATCC 35469 altronate hydrolase YP_002385391.1 4488200 D 585054 CDS YP_002385392.1 218551600 7122650 4489764..4490330 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 4490330 ygjV 7122650 ygjV Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385392.1 4489764 D 585054 CDS YP_002385393.1 218551601 7123065 complement(4490334..4491578) 1 NC_011740.1 involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 4491578 sstT 7123065 sstT Escherichia fergusonii ATCC 35469 serine/threonine transporter SstT YP_002385393.1 4490334 R 585054 CDS YP_002385394.1 218551602 7121946 complement(4491786..4492754) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12107143, 2108134; Product type pm : membrane component; hypothetical protein 4492754 alx 7121946 alx Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385394.1 4491786 R 585054 CDS YP_002385395.1 218551603 7121939 complement(4493037..4494041) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; NAD(P)-binding dehydrogenase 4494041 ygjR 7121939 ygjR Escherichia fergusonii ATCC 35469 NAD(P)-binding dehydrogenase YP_002385395.1 4493037 R 585054 CDS YP_002385396.1 218551604 7119874 complement(4494878..4495381) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; metal dependent hydrolase 4495381 ygjP 7119874 ygjP Escherichia fergusonii ATCC 35469 metal dependent hydrolase YP_002385396.1 4494878 R 585054 CDS YP_002385397.1 218551605 7123064 4495466..4496602 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; methyltransferase small domain 4496602 ygjO 7123064 ygjO Escherichia fergusonii ATCC 35469 methyltransferase small domain YP_002385397.1 4495466 D 585054 CDS YP_002385398.1 218551606 7119872 4496735..4497553 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4497553 7119872 EFER_4395 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385398.1 4496735 D 585054 CDS YP_002385399.1 218551607 7120474 complement(4497637..4499928) 1 NC_011740.1 catalyzes the transfer of phosphoglycerol to the glucan backbone; phosphoglycerol transferase I 4499928 mdoB 7120474 mdoB Escherichia fergusonii ATCC 35469 phosphoglycerol transferase I YP_002385399.1 4497637 R 585054 CDS YP_002385400.1 218551608 7121243 complement(4500182..4500676) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4500676 yjjA 7121243 yjjA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385400.1 4500182 R 585054 CDS YP_002385401.1 218551609 7122035 complement(4500727..4501464) 1 NC_011740.1 acts to load the DnaB helicase onto the initiation site during DNA replication; DNA replication protein DnaC 4501464 dnaC 7122035 dnaC Escherichia fergusonii ATCC 35469 DNA replication protein DnaC YP_002385401.1 4500727 R 585054 CDS YP_002385402.1 218551610 7122909 complement(4501467..4502018) 1 NC_011740.1 This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'; primosomal protein DnaI 4502018 dnaT 7122909 dnaT Escherichia fergusonii ATCC 35469 primosomal protein DnaI YP_002385402.1 4501467 R 585054 CDS YP_002385403.2 229598032 7124125 complement(4502114..4502587) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4502587 7124125 EFER_4400 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385403.2 4502114 R 585054 CDS YP_002385404.1 218551612 7120475 complement(4502578..4503354) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 4503354 yjjP 7120475 yjjP Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385404.1 4502578 R 585054 CDS YP_002385405.1 218551613 7122039 4503641..4504828 1 NC_011740.1 catalyzes the formation of protocatechuate from 4-hydroxybenzoate; 4-hydroxybenzoate 3-monooxygenase 4504828 7122039 EFER_4403 Escherichia fergusonii ATCC 35469 4-hydroxybenzoate 3-monooxygenase YP_002385405.1 4503641 D 585054 CDS YP_002385406.1 218551614 7123706 4504785..4505738 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator 4505738 7123706 EFER_4404 Escherichia fergusonii ATCC 35469 transcriptional regulator YP_002385406.1 4504785 D 585054 CDS YP_002385407.1 218551615 7120476 4505956..4506681 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator YjjQ12 4506681 7120476 EFER_4405 Escherichia fergusonii ATCC 35469 DNA-binding transcriptional regulator YjjQ12 YP_002385407.1 4505956 D 585054 CDS YP_002385408.1 218551616 7120477 4506639..4507310 1 NC_011740.1 regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin; DNA-binding transcriptional activator BglJ 4507310 7120477 EFER_4406 Escherichia fergusonii ATCC 35469 DNA-binding transcriptional activator BglJ YP_002385408.1 4506639 D 585054 CDS YP_002385409.1 218551617 7120478 complement(4507370..4508158) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11931550, 14756576, 3323834, 9990318; Product type c : carrier; ferric hydroximate transport ferric iron reductase 4508158 fhuF 7120478 fhuF Escherichia fergusonii ATCC 35469 ferric hydroximate transport ferric iron reductase YP_002385409.1 4507370 R 585054 CDS YP_002385410.1 218551618 7120016 4508299..4508535 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4508535 yjjZ 7120016 yjjZ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385410.1 4508299 D 585054 CDS YP_002385411.1 218551619 7123635 complement(4509330..4509749) 1 NC_011740.1 Evidence 5 : No homology to any previously reported sequences; PubMedId : 15849754; hypothetical protein 4509749 7123635 EFER_4411 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385411.1 4509330 R 585054 CDS YP_002385412.1 218551620 7120479 complement(4510163..4511194) 1 NC_011740.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase 4511194 rsmC 7120479 rsmC Escherichia fergusonii ATCC 35469 16S ribosomal RNA m2G1207 methyltransferase YP_002385412.1 4510163 R 585054 CDS YP_002385413.1 218551621 7121150 4511297..4511710 1 NC_011740.1 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi 4511710 holD 7121150 holD Escherichia fergusonii ATCC 35469 DNA polymerase III subunit psi YP_002385413.1 4511297 D 585054 CDS YP_002385414.1 218551622 7122211 4511679..4512125 1 NC_011740.1 alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase 4512125 rimI 7122211 rimI Escherichia fergusonii ATCC 35469 ribosomal-protein-alanine N-acetyltransferase YP_002385414.1 4511679 D 585054 CDS YP_002385415.1 218551623 7123863 4512140..4512817 1 NC_011740.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase 4512817 yjjG 7123863 yjjG Escherichia fergusonii ATCC 35469 nucleotidase YP_002385415.1 4512140 D 585054 CDS YP_002385416.1 218551624 7122036 4513203..4514426 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; integrase 4514426 7122036 EFER_4416 Escherichia fergusonii ATCC 35469 integrase YP_002385416.1 4513203 D 585054 CDS YP_002385417.1 218551625 7120480 complement(4514687..4515019) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9358034; Product type h : extrachromosomal origin; hypothetical protein 4515019 flxA 7120480 flxA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385417.1 4514687 R 585054 CDS YP_002385418.1 218551626 7122998 complement(4515732..4516268) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 4516268 yfdR 7122998 yfdR Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385418.1 4515732 R 585054 CDS YP_002385419.1 218551627 7119836 complement(4516397..4517221) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 4517221 yfdQ 7119836 yfdQ Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385419.1 4516397 R 585054 CDS YP_002385420.1 218551628 7119834 complement(4517287..4517967) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4517967 7119834 EFER_4420 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385420.1 4517287 R 585054 CDS YP_002385421.1 218551629 7123166 complement(4517747..4518034) 1 NC_011740.1 Evidence 6 : Doubtful CDS; Product type h : extrachromosomal origin; hypothetical protein 4518034 7123166 EFER_4421 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385421.1 4517747 R 585054 CDS YP_002385422.1 218551630 7120481 4517855..4518634 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 4518634 7120481 EFER_4422 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385422.1 4517855 D 585054 CDS YP_002385423.1 218551631 7123167 complement(4518862..4519488) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Repressor protein C2 4519488 cII 7123167 cII Escherichia fergusonii ATCC 35469 Repressor protein C2 YP_002385423.1 4518862 R 585054 CDS YP_002385424.1 218551632 7120893 4519587..4519787 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; repressor protein dicC 4519787 7120893 EFER_4424 Escherichia fergusonii ATCC 35469 repressor protein dicC YP_002385424.1 4519587 D 585054 CDS YP_002385425.1 218551633 7120482 4519711..4520376 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; nucleic acid-binding protein; e14 prophage 4520376 ymfL 7120482 ymfL Escherichia fergusonii ATCC 35469 nucleic acid-binding protein; e14 prophage YP_002385425.1 4519711 D 585054 CDS YP_002385426.1 218551634 7122057 4520373..4520711 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 4520711 ymfM 7122057 ymfM Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385426.1 4520373 D 585054 CDS YP_002385427.1 218551635 7122059 4520721..4521662 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; phage replication protein O 4521662 7122059 EFER_4428 Escherichia fergusonii ATCC 35469 phage replication protein O YP_002385427.1 4520721 D 585054 CDS YP_002385428.1 218551636 7120483 4521659..4522153 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 4522153 yfdN 7120483 yfdN Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385428.1 4521659 D 585054 CDS YP_002385429.1 218551637 7119833 4522120..4522479 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 4522479 7119833 EFER_4430 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385429.1 4522120 D 585054 CDS YP_002385430.1 218551638 7123168 4522476..4522865 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Crossover junction endodeoxyribonuclease 4522865 rusA 7123168 rusA Escherichia fergusonii ATCC 35469 Crossover junction endodeoxyribonuclease YP_002385430.1 4522476 D 585054 CDS YP_002385431.1 218551639 7121167 4522885..4523682 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 4523682 7121167 EFER_4432 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385431.1 4522885 D 585054 CDS YP_002385432.1 218551640 7123707 4523684..4524679 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4524679 7123707 EFER_4433 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385432.1 4523684 D 585054 CDS YP_002385433.1 218551641 7120484 4524693..4525445 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; antitermination protein Q; Qin prophage 4525445 ydfT 7120484 ydfT Escherichia fergusonii ATCC 35469 antitermination protein Q; Qin prophage YP_002385433.1 4524693 D 585054 CDS YP_002385434.1 218551642 7122698 complement(4525861..4526073) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9484881, 8022261, 9439003; Product type h : extrachromosomal origin; cold shock protein; Qin prophage 4526073 cspF 7122698 cspF Escherichia fergusonii ATCC 35469 cold shock protein; Qin prophage YP_002385434.1 4525861 R 585054 CDS YP_002385435.1 218551643 7123538 4526376..4526591 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94293754, 94293756, 9439003; Product type h : extrachromosomal origin; cold shock protein; Qin prophage 4526591 cspB 7123538 cspB Escherichia fergusonii ATCC 35469 cold shock protein; Qin prophage YP_002385435.1 4526376 D 585054 CDS YP_002385436.1 218551644 7122818 4527344..4527559 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; S lysis protein; Qin prophage 4527559 essQ 7122818 essQ Escherichia fergusonii ATCC 35469 S lysis protein; Qin prophage YP_002385436.1 4527344 D 585054 CDS YP_002385437.1 218551645 7119965 4527543..4528115 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 4528115 7119965 EFER_4438 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385437.1 4527543 D 585054 CDS YP_002385438.1 218551646 7120486 4528437..4528970 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; membrane-associated lysozyme; Qin prophage 4528970 ydfQ 7120486 ydfQ Escherichia fergusonii ATCC 35469 membrane-associated lysozyme; Qin prophage YP_002385438.1 4528437 D 585054 CDS YP_002385439.1 218551647 7123520 4528967..4529464 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 4529464 ydfP 7123520 ydfP Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385439.1 4528967 D 585054 CDS YP_002385440.1 218551648 7124090 4529828..4530040 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9484881; Product type h : extrachromosomal origin; cold shock protein; Qin prophage 4530040 cspI 7124090 cspI Escherichia fergusonii ATCC 35469 cold shock protein; Qin prophage YP_002385440.1 4529828 D 585054 CDS YP_002385441.1 218551649 7122822 4530386..4530541 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 4530541 ynfN 7122822 ynfN Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385441.1 4530386 D 585054 CDS YP_002385442.1 218551650 7121712 4530621..4530887 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4530887 7121712 EFER_4444 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385442.1 4530621 D 585054 CDS YP_002385443.1 218551651 7120487 4531183..4531389 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 4531389 7120487 EFER_4445 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385443.1 4531183 D 585054 CDS YP_002385444.1 218551652 7123708 4531942..4532433 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 4532433 7123708 EFER_4446 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385444.1 4531942 D 585054 CDS YP_002385445.1 218551653 7120488 4532433..4534535 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; DNA packaging protein of prophage ( terminase large subunit) 4534535 7120488 EFER_4447 Escherichia fergusonii ATCC 35469 DNA packaging protein of prophage ( terminase large subunit) YP_002385445.1 4532433 D 585054 CDS YP_002385446.1 218551654 7120489 4534526..4534744 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 4534744 7120489 EFER_4448 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385446.1 4534526 D 585054 CDS YP_002385447.1 218551655 7123169 4534672..4536252 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; portal protein (head-tail preconnector protein) from prophage 4536252 7123169 EFER_4449 Escherichia fergusonii ATCC 35469 portal protein (head-tail preconnector protein) from prophage YP_002385447.1 4534672 D 585054 CDS YP_002385448.1 218551656 7120490 4536005..4538224 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; ATP-dependent Clp protease proteolytic subunit 4538224 7120490 EFER_4450 Escherichia fergusonii ATCC 35469 ATP-dependent Clp protease proteolytic subunit YP_002385448.1 4536005 D 585054 CDS YP_002385449.1 218551657 7120491 4538266..4538634 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 4538634 7120491 EFER_4451 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385449.1 4538266 D 585054 CDS YP_002385450.1 218551658 7123170 4538627..4538902 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 4538902 7123170 EFER_4452 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385450.1 4538627 D 585054 CDS YP_002385451.1 218551659 7120492 4538914..4539492 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein Z (GPZ) of prophage 4539492 7120492 EFER_4453 Escherichia fergusonii ATCC 35469 Minor tail protein Z (GPZ) of prophage YP_002385451.1 4538914 D 585054 CDS YP_002385452.1 218551660 7120493 4539477..4539890 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein U 4539890 7120493 EFER_4454 Escherichia fergusonii ATCC 35469 Minor tail protein U YP_002385452.1 4539477 D 585054 CDS YP_002385453.1 218551661 7120494 4539896..4540645 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Major tail protein V 4540645 7120494 EFER_4455 Escherichia fergusonii ATCC 35469 Major tail protein V YP_002385453.1 4539896 D 585054 CDS YP_002385454.1 218551662 7120495 4540664..4541092 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; minor tail protein 4541092 7120495 EFER_4456 Escherichia fergusonii ATCC 35469 minor tail protein YP_002385454.1 4540664 D 585054 CDS YP_002385455.1 218551663 7120496 4541101..4541430 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; minor tail protein T of prophage 4541430 7120496 EFER_4457 Escherichia fergusonii ATCC 35469 minor tail protein T of prophage YP_002385455.1 4541101 D 585054 CDS YP_002385456.1 218551664 7120497 4541372..4544467 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; tail length tape measure protein from prophage 4544467 7120497 EFER_4458 Escherichia fergusonii ATCC 35469 tail length tape measure protein from prophage YP_002385456.1 4541372 D 585054 CDS YP_002385457.1 218551665 7123709 4544467..4544796 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein M 4544796 7123709 EFER_4459 Escherichia fergusonii ATCC 35469 Minor tail protein M YP_002385457.1 4544467 D 585054 CDS YP_002385458.1 218551666 7120498 4544806..4545504 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein L 4545504 7120498 EFER_4460 Escherichia fergusonii ATCC 35469 Minor tail protein L YP_002385458.1 4544806 D 585054 CDS YP_002385459.1 218551667 7123171 4545510..4546253 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; tail fiber component K of prophage 4546253 7123171 EFER_4461 Escherichia fergusonii ATCC 35469 tail fiber component K of prophage YP_002385459.1 4545510 D 585054 CDS YP_002385460.1 218551668 7120499 4546151..4546798 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; tail assembly protein I from prophage 4546798 7120499 EFER_4462 Escherichia fergusonii ATCC 35469 tail assembly protein I from prophage YP_002385460.1 4546151 D 585054 CDS YP_002385461.1 218551669 7120500 4546859..4550347 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Host specificity protein J of prophage 4550347 7120500 EFER_4463 Escherichia fergusonii ATCC 35469 Host specificity protein J of prophage YP_002385461.1 4546859 D 585054 CDS YP_002385462.1 218551670 7123172 4550415..4551014 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; Lom-like outer membrane protein of prophage 4551014 7123172 EFER_4464 Escherichia fergusonii ATCC 35469 Lom-like outer membrane protein of prophage YP_002385462.1 4550415 D 585054 CDS YP_002385463.1 218551671 7123710 4551073..4554453 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; side tail fiber protein of prophage 4554453 7123710 EFER_4465 Escherichia fergusonii ATCC 35469 side tail fiber protein of prophage YP_002385463.1 4551073 D 585054 CDS YP_002385464.1 218551672 7120502 4554453..4555028 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; tail fiber chaperone; Qin prophage 4555028 tfaQ 7120502 tfaQ Escherichia fergusonii ATCC 35469 tail fiber chaperone; Qin prophage YP_002385464.1 4554453 D 585054 CDS YP_002385465.1 218551673 7121988 complement(4555126..4555716) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14687564; Product type pe : enzyme; site-specific recombinase; DNA invertase; Rac prophage 4555716 pinR 7121988 pinR Escherichia fergusonii ATCC 35469 site-specific recombinase; DNA invertase; Rac prophage YP_002385465.1 4555126 R 585054 CDS YP_002385466.1 218551674 7120086 complement(4556096..4556362) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4556362 ydfK 7120086 ydfK Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385466.1 4556096 R 585054 CDS YP_002385467.1 218551675 7122697 complement(4556938..4557186) 1 NC_011740.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 11230150; Product type f : factor; DNA damage-inducible protein in prophage (dinI-like) 4557186 7122697 EFER_4470 Escherichia fergusonii ATCC 35469 DNA damage-inducible protein in prophage (dinI-like) YP_002385467.1 4556938 R 585054 CDS YP_002385468.1 218551676 7120503 4557379..4558992 1 NC_011740.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 4558992 prfC 7120503 prfC Escherichia fergusonii ATCC 35469 peptide chain release factor 3 YP_002385468.1 4557379 D 585054 CDS YP_002385469.1 218551677 7123108 4559385..4559990 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1317380, 8253679, 9298646, 9600841; Product type cp : cell process; hypothetical protein 4559990 osmY 7123108 osmY Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385469.1 4559385 D 585054 CDS YP_002385470.1 218551678 7119703 4560099..4560278 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4560278 ytjA 7119703 ytjA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385470.1 4560099 D 585054 CDS YP_002385471.1 218551679 7119769 4560400..4561473 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; esterase 4561473 yjjU 7119769 yjjU Escherichia fergusonii ATCC 35469 esterase YP_002385471.1 4560400 D 585054 CDS YP_002385472.1 218551680 7123413 4561470..4562252 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; deoxyribonuclease YjjV 4562252 yjjV 7123413 yjjV Escherichia fergusonii ATCC 35469 deoxyribonuclease YjjV YP_002385472.1 4561470 D 585054 CDS YP_002385473.1 218551681 7122040 complement(4562382..4563245) 1 NC_011740.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; pyruvate formate lyase activating enzyme 4563245 yjjW 7122040 yjjW Escherichia fergusonii ATCC 35469 pyruvate formate lyase activating enzyme YP_002385473.1 4562382 R 585054 CDS YP_002385474.1 218551682 7123970 complement(4563217..4564767) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4564767 yjjI 7123970 yjjI Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385474.1 4563217 R 585054 CDS YP_002385475.1 218551683 7122037 4565025..4565804 1 NC_011740.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 4565804 deoC 7122037 deoC Escherichia fergusonii ATCC 35469 deoxyribose-phosphate aldolase YP_002385475.1 4565025 D 585054 CDS YP_002385476.1 218551684 7122888 4565882..4567204 1 NC_011740.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 4567204 deoA 7122888 deoA Escherichia fergusonii ATCC 35469 thymidine phosphorylase YP_002385476.1 4565882 D 585054 CDS YP_002385477.1 218551685 7122886 4567256..4568479 1 NC_011740.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 4568479 deoB 7122886 deoB Escherichia fergusonii ATCC 35469 phosphopentomutase YP_002385477.1 4567256 D 585054 CDS YP_002385478.1 218551686 7122887 4568536..4569255 1 NC_011740.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 4569255 deoD 7122887 deoD Escherichia fergusonii ATCC 35469 purine nucleoside phosphorylase YP_002385478.1 4568536 D 585054 CDS YP_002385479.1 218551687 7122889 complement(4569416..4569679) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4569679 7122889 EFER_4482 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385479.1 4569416 R 585054 CDS YP_002385480.1 218551688 7120504 complement(4569711..4570727) 1 NC_011740.1 Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins; lipoate-protein ligase A 4570727 lplA 7120504 lplA Escherichia fergusonii ATCC 35469 lipoate-protein ligase A YP_002385480.1 4569711 R 585054 CDS YP_002385481.1 218551689 7120850 complement(4570755..4571399) 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2684780; hypothetical protein 4571399 ytjB 7120850 ytjB Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385481.1 4570755 R 585054 CDS YP_002385482.1 218551690 7123591 4571505..4572473 1 NC_011740.1 catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase 4572473 serB 7123591 serB Escherichia fergusonii ATCC 35469 phosphoserine phosphatase YP_002385482.1 4571505 D 585054 CDS YP_002385483.1 218551691 7123920 4572522..4573904 1 NC_011740.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 4573904 radA 7123920 radA Escherichia fergusonii ATCC 35469 DNA repair protein RadA YP_002385483.1 4572522 D 585054 CDS YP_002385484.1 218551692 7122344 4573925..4575157 1 NC_011740.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase 4575157 nadR 7122344 nadR Escherichia fergusonii ATCC 35469 nicotinamide-nucleotide adenylyltransferase YP_002385484.1 4573925 D 585054 CDS YP_002385485.1 218551693 7123199 4575171..4575581 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4575581 7123199 EFER_4488 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385485.1 4575171 D 585054 CDS YP_002385486.1 218551694 7123711 4575571..4575867 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4575867 7123711 EFER_4489 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385486.1 4575571 D 585054 CDS YP_002385487.1 218551695 7120505 complement(4575923..4577590) 1 NC_011740.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein 4577590 yjjK 7120505 yjjK Escherichia fergusonii ATCC 35469 ABC transporter ATP-binding protein YP_002385487.1 4575923 R 585054 CDS YP_002385488.1 218551696 7122038 4577801..4579738 1 NC_011740.1 catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan; lytic murein transglycosylase 4579738 slt 7122038 slt Escherichia fergusonii ATCC 35469 lytic murein transglycosylase YP_002385488.1 4577801 D 585054 CDS YP_002385489.1 218551697 7121789 4579828..4580154 1 NC_011740.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 4580154 trpR 7121789 trpR Escherichia fergusonii ATCC 35469 Trp operon repressor YP_002385489.1 4579828 D 585054 CDS YP_002385490.1 218551698 7122167 complement(4580148..4580672) 1 NC_011740.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog; NTPase 4580672 yjjX 7122167 yjjX Escherichia fergusonii ATCC 35469 NTPase YP_002385490.1 4580148 R 585054 CDS YP_002385491.1 218551699 7123971 4580715..4581362 1 NC_011740.1 catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate; phosphoglycerate mutase 4581362 ytjC 7123971 ytjC Escherichia fergusonii ATCC 35469 phosphoglycerate mutase YP_002385491.1 4580715 D 585054 CDS YP_002385492.1 218551700 7119770 complement(4581359..4582228) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20264525, 20309711, 93194823, 96405618, 8449900; Product type r : regulator; DNA-binding transcriptional activator 4582228 rob 7119770 rob Escherichia fergusonii ATCC 35469 DNA-binding transcriptional activator YP_002385492.1 4581359 R 585054 CDS YP_002385493.1 218551701 7121432 4582439..4582912 1 NC_011740.1 Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3531171, 8449900; hypothetical protein 4582912 creA 7121432 creA Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385493.1 4582439 D 585054 CDS YP_002385494.1 218551702 7122802 4582925..4583614 1 NC_011740.1 response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; DNA-binding response regulator CreB 4583614 creB 7122802 creB Escherichia fergusonii ATCC 35469 DNA-binding response regulator CreB YP_002385494.1 4582925 D 585054 CDS YP_002385495.1 218551703 7122803 4583614..4585038 1 NC_011740.1 part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; sensory histidine kinase CreC 4585038 creC 7122803 creC Escherichia fergusonii ATCC 35469 sensory histidine kinase CreC YP_002385495.1 4583614 D 585054 CDS YP_002385496.1 218551704 7122804 4585096..4586454 1 NC_011740.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type m : membrane component; hypothetical protein 4586454 creD 7122804 creD Escherichia fergusonii ATCC 35469 hypothetical protein YP_002385496.1 4585096 D 585054 CDS YP_002385497.1 218551705 7122805 complement(4586519..4587235) 1 NC_011740.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15028693, 21167794, 21317451, 91008980, 91358353, 92380937, 9514749, 9632255, 2984198, 7565118, 9298646; Product type r : regulator; two-component response regulator 4587235 arcA 7122805 arcA Escherichia fergusonii ATCC 35469 two-component response regulator YP_002385497.1 4586519 R 585054 CDS YP_002385498.1 218551706 7123176 4587869..4588555 1 NC_011740.1 member of the SPOUT superfamily of methyltransferases; RNA methyltransferase 4588555 yjtD 7123176 yjtD Escherichia fergusonii ATCC 35469 RNA methyltransferase YP_002385498.1 4587869 D 585054 CDS YP_002394549.1 218561637 7133892 450..1316 1 NC_011743.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 8469120; Product type r : regulator; Replication protein 1316 repB 7133892 repB Escherichia fergusonii ATCC 35469 Replication protein YP_002394549.1 450 D 585054 CDS YP_002394550.1 218561638 7133884 complement(1637..1855) 1 NC_011743.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1855 7133884 pEFER_0002 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002394550.1 1637 R 585054 CDS YP_002394551.1 218561639 7133834 1840..2007 1 NC_011743.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2007 7133834 pEFER_0003 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002394551.1 1840 D 585054 CDS YP_002394552.1 218561640 7133835 2249..3454 1 NC_011743.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7961987; Product type e : enzyme; Plasmid partition protein A 3454 parA 7133835 parA Escherichia fergusonii ATCC 35469 Plasmid partition protein A YP_002394552.1 2249 D 585054 CDS YP_002394553.1 218561641 7133882 3451..4428 1 NC_011743.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 16677298; Product type e : enzyme; Plasmid Partition par B protein 4428 parB 7133882 parB Escherichia fergusonii ATCC 35469 Plasmid Partition par B protein YP_002394553.1 3451 D 585054 CDS YP_002394554.1 218561642 7133883 complement(4510..5781) 1 NC_011743.1 binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuC 5781 umuC 7133883 umuC Escherichia fergusonii ATCC 35469 DNA polymerase V subunit UmuC YP_002394554.1 4510 R 585054 CDS YP_002394555.1 218561643 7133887 complement(5781..6488) 1 NC_011743.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 2129552, 10024589; Product type e : enzyme; Protein impA [Contains: Protein impA'] (modular protein) 6488 7133887 pEFER_0007 Escherichia fergusonii ATCC 35469 Protein impA [Contains: Protein impA'] (modular protein) YP_002394555.1 5781 R 585054 CDS YP_002394556.1 218561644 7133836 6370..6537 1 NC_011743.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 6537 7133836 pEFER_0008 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002394556.1 6370 D 585054 CDS YP_002394557.1 218561645 7133837 6557..7309 1 NC_011743.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; reverse transcriptase/maturase, RetA (fragment) 7309 7133837 pEFER_0009 Escherichia fergusonii ATCC 35469 reverse transcriptase/maturase, RetA (fragment) YP_002394557.1 6557 D 585054 CDS YP_002394560.1 218561648 7133840 7461..7736 1 NC_011743.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase, ORF A, insertion element IS1 7736 7133840 pEFER_0012 Escherichia fergusonii ATCC 35469 transposase, ORF A, insertion element IS1 YP_002394560.1 7461 D 585054 CDS YP_002394561.1 218561649 7133841 7655..8158 1 NC_011743.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; tranposase, ORF B, insertion element IS1 8158 7133841 pEFER_0013 Escherichia fergusonii ATCC 35469 tranposase, ORF B, insertion element IS1 YP_002394561.1 7655 D 585054 CDS YP_002394562.1 218561650 7133842 9008..9307 1 NC_011743.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 9307 7133842 pEFER_0014 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002394562.1 9008 D 585054 CDS YP_002394563.1 218561651 7133843 9620..10588 1 NC_011743.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 2993802; Product type pe : putative enzyme; transposase, IS903.B 10588 7133843 pEFER_0015 Escherichia fergusonii ATCC 35469 transposase, IS903.B YP_002394563.1 9620 D 585054 CDS YP_002394564.1 218561652 7133844 10781..10999 1 NC_011743.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 10999 7133844 pEFER_0016 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002394564.1 10781 D 585054 CDS YP_002394565.1 218561653 7133845 11390..12061 1 NC_011743.1 Evidence 7 : Gene remnant; Product type pe : putative enzyme; hypothetical protein 12061 7133845 pEFER_0017 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002394565.1 11390 D 585054 CDS YP_002394566.1 218561654 7133846 complement(12093..12272) 1 NC_011743.1 Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; phage protein 12272 7133846 pEFER_0018 Escherichia fergusonii ATCC 35469 phage protein YP_002394566.1 12093 R 585054 CDS YP_002394567.1 218561655 7133847 12109..12813 1 NC_011743.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 12813 7133847 pEFER_0019 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002394567.1 12109 D 585054 CDS YP_002394568.1 218561656 7133848 12882..13808 1 NC_011743.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 13808 7133848 pEFER_0020 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002394568.1 12882 D 585054 CDS YP_002394569.1 218561657 7133849 13818..14417 1 NC_011743.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 14417 7133849 pEFER_0021 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002394569.1 13818 D 585054 CDS YP_002394570.1 218561658 7133850 14405..14998 1 NC_011743.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 14998 7133850 pEFER_0022 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002394570.1 14405 D 585054 CDS YP_002394571.1 218561659 7133851 15017..18694 1 NC_011743.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; ATPase (modular protein) 18694 7133851 pEFER_0023 Escherichia fergusonii ATCC 35469 ATPase (modular protein) YP_002394571.1 15017 D 585054 CDS YP_002394572.1 218561660 7133852 18711..20474 1 NC_011743.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 20474 7133852 pEFER_0024 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002394572.1 18711 D 585054 CDS YP_002394573.1 218561661 7133853 20490..24143 1 NC_011743.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 24143 7133853 pEFER_0025 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002394573.1 20490 D 585054 CDS YP_002394574.1 218561662 7133854 24143..26800 1 NC_011743.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 26800 7133854 pEFER_0026 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002394574.1 24143 D 585054 CDS YP_002394575.1 218561663 7133855 26817..28892 1 NC_011743.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; ATP-dependent Lon protease 28892 7133855 pEFER_0027 Escherichia fergusonii ATCC 35469 ATP-dependent Lon protease YP_002394575.1 26817 D 585054 CDS YP_002394576.1 218561664 7133856 complement(28885..29631) 1 NC_011743.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 29631 7133856 pEFER_0028 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002394576.1 28885 R 585054 CDS YP_002394577.1 218561665 7133857 complement(29000..29179) 1 NC_011743.1 Evidence 7 : Gene remnant; Product type pe : putative enzyme; hypothetical protein 29179 7133857 pEFER_0029 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002394577.1 29000 R 585054 CDS YP_002394578.1 218561666 7133858 complement(29749..32634) 1 NC_011743.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 3029727; Product type e : enzyme; Similar to TnpA transposase 32634 tnpA 7133858 tnpA Escherichia fergusonii ATCC 35469 Similar to TnpA transposase YP_002394578.1 29749 R 585054 CDS YP_002394579.1 218561667 7133891 32760..33383 1 NC_011743.1 resolvase 33383 7133891 pEFER_0031 Escherichia fergusonii ATCC 35469 resolvase YP_002394579.1 32760 D 585054 CDS YP_002394580.1 218561668 7133859 33393..33689 1 NC_011743.1 YahA protein 33689 7133859 pEFER_0032 Escherichia fergusonii ATCC 35469 YahA protein YP_002394580.1 33393 D 585054 CDS YP_002394581.1 218561669 7133880 complement(34376..37540) 1 NC_011743.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 391406; Product type pe : putative enzyme; transposase 37540 7133880 pEFER_0034 Escherichia fergusonii ATCC 35469 transposase YP_002394581.1 34376 R 585054 CDS YP_002394582.1 218561670 7133861 37509..38102 1 NC_011743.1 Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; Resolvase transposon Tn3 38102 7133861 pEFER_0035 Escherichia fergusonii ATCC 35469 Resolvase transposon Tn3 YP_002394582.1 37509 D 585054 CDS YP_002394583.1 218561671 7133862 38285..39145 1 NC_011743.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 358200, 3019092, 15769331; Product type e : enzyme; Beta-lactamase TEM precursor (Penicillinase) 39145 bla 7133862 bla Escherichia fergusonii ATCC 35469 Beta-lactamase TEM precursor (Penicillinase) YP_002394583.1 38285 D 585054 CDS YP_002394584.1 218561672 7133879 39261..39854 1 NC_011743.1 transposase (fragment) 39854 7133879 pEFER_0037 Escherichia fergusonii ATCC 35469 transposase (fragment) YP_002394584.1 39261 D 585054 CDS YP_002394585.1 218561673 7133863 complement(39864..40280) 1 NC_011743.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10781570, 6094472, 6094471; Product type pr : putative regulator; TetD, putative operon control protein 40280 tetD 7133863 tetD Escherichia fergusonii ATCC 35469 TetD, putative operon control protein YP_002394585.1 39864 R 585054 CDS YP_002394586.1 218561674 7133890 40293..40961 1 NC_011743.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10781570, 6094472, 6094471; Product type pr : putative regulator; transcriptional regulator TetC 40961 tetC 7133890 tetC Escherichia fergusonii ATCC 35469 transcriptional regulator TetC YP_002394586.1 40293 D 585054 CDS YP_002394587.1 218561675 7133889 complement(41074..42327) 1 NC_011743.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 10783303; Product type t : transporter; Tetracycline resistance protein, class B (TETA(B) ) (Metal-tetracycline/H(+) antiporter) 42327 tetA 7133889 tetA Escherichia fergusonii ATCC 35469 Tetracycline resistance protein, class B (TETA(B) ) (Metal-tetracycline/H(+) antiporter) YP_002394587.1 41074 R 585054 CDS YP_002394588.1 218561676 7133888 42358..42984 1 NC_011743.1 Evidence 2b : Function of strongly homologous gene; Product type r : regulator; tetracycline repressor protein TetR 42984 7133888 pEFER_0041 Escherichia fergusonii ATCC 35469 tetracycline repressor protein TetR YP_002394588.1 42358 D 585054 CDS YP_002394589.1 218561677 7133864 complement(42962..43648) 1 NC_011743.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; ArsR family regulatory protein 43648 7133864 pEFER_0042 Escherichia fergusonii ATCC 35469 ArsR family regulatory protein YP_002394589.1 42962 R 585054 CDS YP_002394590.1 218561678 7133865 complement(43656..44153) 1 NC_011743.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 44153 7133865 pEFER_0043 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002394590.1 43656 R 585054 CDS YP_002394591.1 218561679 7133866 complement(44035..44355) 1 NC_011743.1 Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; monooxygenase 44355 7133866 pEFER_0044 Escherichia fergusonii ATCC 35469 monooxygenase YP_002394591.1 44035 R 585054 CDS YP_002394592.1 218561680 7133867 44799..46004 1 NC_011743.1 Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10781570; Product type c : carrier; glutamate permease 46004 jemA 7133867 jemA Escherichia fergusonii ATCC 35469 glutamate permease YP_002394592.1 44799 D 585054 CDS YP_002394593.1 218561681 7133881 complement(46370..47578) 1 NC_011743.1 Evidence 2b : Function of strongly homologous gene; PubMedId : 10781570; Product type pe : putative enzyme; transposase, IS10 47578 7133881 pEFER_0046 Escherichia fergusonii ATCC 35469 transposase, IS10 YP_002394593.1 46370 R 585054 CDS YP_002394594.1 218561682 7133886 47864..48667 1 NC_011743.1 Streptomycin 3''-kinase (Streptomycin 3''-phosphotransferase) (Streptomycin 6-phosphotransferase) (Streptomycin 6-kinase) 48667 7133886 pEFER_0048 Escherichia fergusonii ATCC 35469 Streptomycin 3''-kinase (Streptomycin 3''-phosphotransferase) (Streptomycin 6-phosphotransferase) (Streptomycin 6-kinase) YP_002394594.1 47864 D 585054 CDS YP_002394595.1 218561683 7133870 47886..48068 1 NC_011743.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 48068 7133870 pEFER_0047 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002394595.1 47886 D 585054 CDS YP_002394596.1 218561684 7133869 48658..49503 1 NC_011743.1 Streptomycin 3''-kinase 49503 7133869 pEFER_0049 Escherichia fergusonii ATCC 35469 Streptomycin 3''-kinase YP_002394596.1 48658 D 585054 CDS YP_002394597.1 218561685 7133871 complement(49475..50041) 1 NC_011743.1 Evidence 7 : Gene remnant; Product type pe : putative enzyme; hypothetical protein 50041 7133871 pEFER_0050 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002394597.1 49475 R 585054 CDS YP_002394598.1 218561686 7133872 complement(49963..50205) 1 NC_011743.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 50205 7133872 pEFER_0051 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002394598.1 49963 R 585054 CDS YP_002394599.1 218561687 7133873 complement(50260..50847) 1 NC_011743.1 Evidence 7 : Gene remnant; Product type pe : putative enzyme; hypothetical protein 50847 7133873 pEFER_0052 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002394599.1 50260 R 585054 CDS YP_002394600.1 218561688 7133874 complement(51383..51799) 1 NC_011743.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 51799 7133874 pEFER_0053 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002394600.1 51383 R 585054 CDS YP_002394601.1 218561689 7133875 complement(51796..52026) 1 NC_011743.1 Virulence-associated protein vagC 52026 7133875 pEFER_0054 Escherichia fergusonii ATCC 35469 Virulence-associated protein vagC YP_002394601.1 51796 R 585054 CDS YP_002394602.1 218561690 7133876 52600..52950 1 NC_011743.1 Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 52950 7133876 pEFER_0055 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002394602.1 52600 D 585054 CDS YP_002394603.1 218561691 7133877 53001..53744 1 NC_011743.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein, putative membrane transporter 53744 7133877 pEFER_0056 Escherichia fergusonii ATCC 35469 hypothetical protein, putative membrane transporter YP_002394603.1 53001 D 585054 CDS YP_002394604.1 218561692 7133878 53741..54517 1 NC_011743.1 Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3027661; Product type e : enzyme; Resolvase (Protein D) 54517 resD 7133878 resD Escherichia fergusonii ATCC 35469 Resolvase (Protein D) YP_002394604.1 53741 D 585054 CDS YP_002394605.1 218561693 7133885 complement(54575..54865) 1 NC_011743.1 Evidence 5 : No homology to any previously reported sequences; hypothetical protein 54865 7133885 pEFER_0058 Escherichia fergusonii ATCC 35469 hypothetical protein YP_002394605.1 54575 R 585054 CDS