-- dump date 20140619_091602 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 585054000001 SEQ_END SEQ_END NC_011740.1 4588711 4588711 DR NC_011740.1; contig end 4588711..4588711 Escherichia fergusonii ATCC 35469 585054000002 SEQ_END SEQ_END NC_011743.1 55150 55150 DR NC_011743.1; contig end 55150..55150 Escherichia fergusonii ATCC 35469 YP_002381232.1 CDS thrL NC_011740.1 58 123 D involved in threonine biosynthesis; controls the expression of the thrLABC operon; thr operon leader peptide 58..123 Escherichia fergusonii ATCC 35469 7122062 YP_002381233.1 CDS thrA NC_011740.1 205 2667 D multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 205..2667 Escherichia fergusonii ATCC 35469 7122129 YP_002381234.1 CDS thrB NC_011740.1 2669 3598 D catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 2669..3598 Escherichia fergusonii ATCC 35469 7122126 YP_002381235.1 CDS thrC NC_011740.1 3602 4888 D catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 3602..4888 Escherichia fergusonii ATCC 35469 7122127 YP_002381236.1 CDS yaaX NC_011740.1 5101 5400 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 5101..5400 Escherichia fergusonii ATCC 35469 7122128 YP_002381237.1 CDS yaaA NC_011740.1 5437 6210 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(5437..6210) Escherichia fergusonii ATCC 35469 7123473 YP_002381238.1 CDS yaaJ NC_011740.1 6280 7827 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; amino acid sodium/proton transporter complement(6280..7827) Escherichia fergusonii ATCC 35469 7122392 YP_002381239.1 CDS talB NC_011740.1 7987 8940 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8332529, 92334977, 11298760, 7592346, 8805555, 9007983, 9298646; Product type e : enzyme; transaldolase B 7987..8940 Escherichia fergusonii ATCC 35469 7124031 YP_002381240.1 CDS mogA NC_011740.1 9055 9642 D forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 9055..9642 Escherichia fergusonii ATCC 35469 7123405 YP_002381241.1 CDS yaaH NC_011740.1 9676 10242 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(9676..10242) Escherichia fergusonii ATCC 35469 7120955 YP_002381242.1 CDS dnaK NC_011740.1 10750 12666 D heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 10750..12666 Escherichia fergusonii ATCC 35469 7124030 YP_002381243.1 CDS dnaJ NC_011740.1 12755 13885 D chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 12755..13885 Escherichia fergusonii ATCC 35469 7123988 YP_002381244.1 CDS mokC NC_011740.1 13989 14198 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90136075, 92048480, 92048481, 99291074; Product type r : regulator; regulatory protein for HokC, overlaps CDS of hokC complement(13989..14198) Escherichia fergusonii ATCC 35469 7124124 YP_002381245.1 CDS nhaA NC_011740.1 14682 15848 D exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 14682..15848 Escherichia fergusonii ATCC 35469 7121799 YP_002381246.1 CDS nhaR NC_011740.1 15886 16815 D Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC; transcriptional activator NhaR 15886..16815 Escherichia fergusonii ATCC 35469 7120690 YP_002381247.1 CDS rpsT NC_011740.1 16911 17174 R binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 complement(16911..17174) Escherichia fergusonii ATCC 35469 7120692 YP_002381248.1 CDS yaaY NC_011740.1 17277 17495 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 17277..17495 Escherichia fergusonii ATCC 35469 7123815 YP_002381249.1 CDS ribF NC_011740.1 17503 18444 D catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 17503..18444 Escherichia fergusonii ATCC 35469 7122394 YP_002381250.1 CDS ileS NC_011740.1 18487 21303 D IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 18487..21303 Escherichia fergusonii ATCC 35469 7121409 YP_002381251.1 CDS lspA NC_011740.1 21303 21797 D lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 21303..21797 Escherichia fergusonii ATCC 35469 7123210 YP_002381252.1 CDS fkpB NC_011740.1 21905 22354 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 97332650, 2011499; Product type e : enzyme; FKBP-type peptidyl-prolyl cis-trans isomerase 21905..22354 Escherichia fergusonii ATCC 35469 7123828 YP_002381253.1 CDS ispH NC_011740.1 22356 23306 D catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 22356..23306 Escherichia fergusonii ATCC 35469 7122966 YP_002381254.1 CDS rihC NC_011740.1 23372 24286 D catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides; ribonucleoside hydrolase RihC 23372..24286 Escherichia fergusonii ATCC 35469 7120795 YP_002381255.1 CDS EFER_0024 NC_011740.1 24304 24669 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 24304..24669 Escherichia fergusonii ATCC 35469 7121411 YP_002381256.1 CDS citB NC_011740.1 24715 25398 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type r : regulator; DNA-binding response regulator in two-component regulatory system with citA complement(24715..25398) Escherichia fergusonii ATCC 35469 7123748 YP_002381257.1 CDS citA NC_011740.1 25391 27019 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type r : regulator; sensory histidine kinase in two-component regulatory system with citB complement(25391..27019) Escherichia fergusonii ATCC 35469 7120895 YP_002381258.1 CDS oadB NC_011740.1 27162 28463 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; Oxalacetate decarboxylase subunit beta complement(27162..28463) Escherichia fergusonii ATCC 35469 7123238 YP_002381259.1 CDS oadA NC_011740.1 28476 30257 R catalyzes the formation of pyruvate from oxaloacetate; oxaloacetate decarboxylase complement(28476..30257) Escherichia fergusonii ATCC 35469 7119688 YP_002381260.1 CDS oadG NC_011740.1 30273 30521 R catalyzes the decarboxylation of oxaloacetate to form pyruvate and carbon dioxide; oxaloacetate decarboxylase subunit gamma complement(30273..30521) Escherichia fergusonii ATCC 35469 7119687 YP_002381261.1 CDS citP NC_011740.1 30672 32012 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1374406, 1577734, 8810332; Product type t : transporter; Citrate-sodium symporter complement(30672..32012) Escherichia fergusonii ATCC 35469 7123032 YP_002381262.1 CDS citC NC_011740.1 32272 33282 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; citrate lyase synthetase 32272..33282 Escherichia fergusonii ATCC 35469 7120899 YP_002381263.1 CDS citD NC_011740.1 33312 33605 D acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate; citrate lyase subunit gamma 33312..33605 Escherichia fergusonii ATCC 35469 7120896 YP_002381264.1 CDS citE NC_011740.1 33527 34471 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; citrate lyase, citryl-ACP lyase subunit beta 33527..34471 Escherichia fergusonii ATCC 35469 7120897 YP_002381265.1 CDS citF NC_011740.1 34484 36004 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; citrate lyase, citrate-ACP transferase subunit alpha 34484..36004 Escherichia fergusonii ATCC 35469 7120898 YP_002381266.1 CDS citX NC_011740.1 36004 36555 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; apo-citrate lyase phosphoribosyl-dephospho-CoA transferase 36004..36555 Escherichia fergusonii ATCC 35469 7123239 YP_002381267.1 CDS citG NC_011740.1 36533 37444 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; triphosphoribosyl-dephospho-CoA transferase 36533..37444 Escherichia fergusonii ATCC 35469 7120900 YP_002381268.1 CDS dapB NC_011740.1 37603 38424 D catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 37603..38424 Escherichia fergusonii ATCC 35469 7123770 YP_002381269.1 CDS EFER_0039 NC_011740.1 38450 38761 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(38450..38761) Escherichia fergusonii ATCC 35469 7123545 YP_002381270.1 CDS carA NC_011740.1 38879 40027 D catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 38879..40027 Escherichia fergusonii ATCC 35469 7120761 YP_002381271.1 CDS carB NC_011740.1 40045 43266 D four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 40045..43266 Escherichia fergusonii ATCC 35469 7120858 YP_002381272.1 CDS caiF NC_011740.1 43527 43922 D regulator of carnitine metabolism; induces the caiTABCDE and fixABCX operons; DNA-binding transcriptional activator CaiF 43527..43922 Escherichia fergusonii ATCC 35469 7123232 YP_002381273.1 CDS caiE NC_011740.1 44008 44598 R involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities; carnitine operon protein CaiE complement(44008..44598) Escherichia fergusonii ATCC 35469 7120855 YP_002381274.1 CDS caiD NC_011740.1 44604 45446 R catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA; carnitinyl-CoA dehydratase complement(44604..45446) Escherichia fergusonii ATCC 35469 7120854 YP_002381275.1 CDS caiC NC_011740.1 45499 47067 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15731894, 97189569, 7815937; Product type e : enzyme; crotonobetaine/carnitine-CoA ligase complement(45499..47067) Escherichia fergusonii ATCC 35469 7120853 YP_002381276.1 CDS caiB NC_011740.1 47125 48342 R catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine; crotonobetainyl-CoA:carnitine CoA-transferase complement(47125..48342) Escherichia fergusonii ATCC 35469 7123764 YP_002381277.1 CDS caiA NC_011740.1 48413 49555 R catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA; crotonobetainyl-CoA dehydrogenase complement(48413..49555) Escherichia fergusonii ATCC 35469 7120852 YP_002381278.1 CDS caiT NC_011740.1 49586 51100 R catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism; L-carnitine/gamma-butyrobetaine antiporter complement(49586..51100) Escherichia fergusonii ATCC 35469 7122178 YP_002381279.1 CDS fixA NC_011740.1 51573 52343 D required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase; electron transfer flavoprotein FixA 51573..52343 Escherichia fergusonii ATCC 35469 7120856 YP_002381280.1 CDS fixB NC_011740.1 52358 53299 D involved in electron transfer during carnitine metabolism; electron transfer flavoprotein FixB 52358..53299 Escherichia fergusonii ATCC 35469 7123630 YP_002381281.1 CDS fixC NC_011740.1 53350 54636 D FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction; oxidoreductase FixC 53350..54636 Escherichia fergusonii ATCC 35469 7120020 YP_002381282.1 CDS fixX NC_011740.1 54633 54920 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96066354, 12081978; Product type pc : carrier; 4Fe-4S ferredoxin 54633..54920 Escherichia fergusonii ATCC 35469 7120021 YP_002381283.1 CDS yaaU NC_011740.1 54979 56310 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter 54979..56310 Escherichia fergusonii ATCC 35469 7120022 YP_002381284.1 CDS kefF NC_011740.1 56418 56948 D Required for full activity of KefC, a potassium-proton antiporter; glutathione-regulated potassium-efflux system ancillary protein KefF 56418..56948 Escherichia fergusonii ATCC 35469 7122393 YP_002381285.1 CDS kefC NC_011740.1 56941 58803 D transport system that facilitates potassium-efflux; glutathione-regulated potassium-efflux system protein KefC 56941..58803 Escherichia fergusonii ATCC 35469 7123759 YP_002381286.1 CDS folA NC_011740.1 58996 59475 D catalyzes the reduction of dihydrofolate to tetrahydrofolate; dihydrofolate reductase 58996..59475 Escherichia fergusonii ATCC 35469 7120813 YP_002381287.1 CDS EFER_0057 NC_011740.1 59496 59675 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; antitoxin of gyrase inhibiting toxin-antitoxin system 59496..59675 Escherichia fergusonii ATCC 35469 7123001 YP_002381288.1 CDS EFER_0058 NC_011740.1 59792 60241 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(59792..60241) Escherichia fergusonii ATCC 35469 7120762 YP_002381289.1 CDS EFER_0059 NC_011740.1 60277 60876 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(60277..60876) Escherichia fergusonii ATCC 35469 7123749 YP_002381290.1 CDS apaH NC_011740.1 60901 61749 R hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase complement(60901..61749) Escherichia fergusonii ATCC 35469 7120763 YP_002381291.1 CDS apaG NC_011740.1 61756 62133 R protein associated with Co2+ and Mg2+ efflux; ApaG protein complement(61756..62133) Escherichia fergusonii ATCC 35469 7123713 YP_002381292.1 CDS ksgA NC_011740.1 62136 62957 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(62136..62957) Escherichia fergusonii ATCC 35469 7120521 YP_002381293.1 CDS pdxA NC_011740.1 62954 63943 R catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase complement(62954..63943) Escherichia fergusonii ATCC 35469 7120816 YP_002381294.1 CDS surA NC_011740.1 63943 65229 R Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB; peptidyl-prolyl cis-trans isomerase SurA complement(63943..65229) Escherichia fergusonii ATCC 35469 7122571 YP_002381295.1 CDS imp NC_011740.1 65283 67634 R determines N-hexane tolerance and is involved in outer membrane permeability; organic solvent tolerance protein complement(65283..67634) Escherichia fergusonii ATCC 35469 7121967 YP_002381296.1 CDS djlA NC_011740.1 67889 68704 D functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system; Dna-J like membrane chaperone protein 67889..68704 Escherichia fergusonii ATCC 35469 7120736 YP_002381297.1 CDS rluA NC_011740.1 68775 69434 R catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs; 23S rRNA/tRNA pseudouridine synthase A complement(68775..69434) Escherichia fergusonii ATCC 35469 7122901 YP_002381298.1 CDS hepA NC_011740.1 69446 72352 R transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA; ATP-dependent helicase HepA complement(69446..72352) Escherichia fergusonii ATCC 35469 7123866 YP_002381299.1 CDS polB NC_011740.1 72516 74867 R Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; DNA polymerase II complement(72516..74867) Escherichia fergusonii ATCC 35469 7122187 YP_002381300.1 CDS araD NC_011740.1 74942 75637 R catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase complement(74942..75637) Escherichia fergusonii ATCC 35469 7120098 YP_002381301.1 CDS araA NC_011740.1 75740 77242 R catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase complement(75740..77242) Escherichia fergusonii ATCC 35469 7120529 YP_002381302.1 CDS araB NC_011740.1 77253 78953 R catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase complement(77253..78953) Escherichia fergusonii ATCC 35469 7120527 YP_002381303.1 CDS araC NC_011740.1 79291 80136 D positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose; DNA-binding transcriptional regulator AraC 79291..80136 Escherichia fergusonii ATCC 35469 7120528 YP_002381304.1 CDS EFER_0074 NC_011740.1 80358 81590 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; sugar metabolism transcriptional regulator 80358..81590 Escherichia fergusonii ATCC 35469 7123175 YP_002381305.1 CDS EFER_0075 NC_011740.1 81616 82539 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; dihydrodipicolinate synthetase 81616..82539 Escherichia fergusonii ATCC 35469 7120764 YP_002381306.1 CDS EFER_0076 NC_011740.1 82594 83547 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; periplasmic binding protein 82594..83547 Escherichia fergusonii ATCC 35469 7120765 YP_002381307.1 CDS EFER_0077 NC_011740.1 83560 84033 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 83560..84033 Escherichia fergusonii ATCC 35469 7123217 YP_002381308.1 CDS EFER_0078 NC_011740.1 84043 85530 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 84043..85530 Escherichia fergusonii ATCC 35469 7120766 YP_002381309.1 CDS yabI NC_011740.1 85714 86478 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 85714..86478 Escherichia fergusonii ATCC 35469 7120767 YP_002381310.1 CDS thiQ NC_011740.1 86559 87257 R with TbpA and ThiP is part of the thiamine and TPP transport system; thiamine transporter ATP-binding subunit complement(86559..87257) Escherichia fergusonii ATCC 35469 7122395 YP_002381311.1 CDS thiP NC_011740.1 87241 88851 R permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein complement(87241..88851) Escherichia fergusonii ATCC 35469 7121998 YP_002381312.1 CDS tbpA NC_011740.1 88827 89810 R part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit complement(88827..89810) Escherichia fergusonii ATCC 35469 7121997 YP_002381313.1 CDS sgrR NC_011740.1 89974 91629 R activates sgrS under glucose-phosphate stress conditions; transcriptional regulator SgrR complement(89974..91629) Escherichia fergusonii ATCC 35469 7121982 YP_002381314.1 CDS setA NC_011740.1 91949 93127 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10438463, 10209755; Product type t : transporter; broad specificity sugar efflux system 91949..93127 Escherichia fergusonii ATCC 35469 7121780 YP_002381315.1 CDS EFER_0088 NC_011740.1 94730 95626 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; LysR family transcriptional regulator 94730..95626 Escherichia fergusonii ATCC 35469 7120768 YP_002381316.1 CDS aroD NC_011740.1 95663 96430 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; 3-dehydroquinate dehydratase complement(95663..96430) Escherichia fergusonii ATCC 35469 7120769 YP_002381317.1 CDS EFER_0090 NC_011740.1 96448 97740 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; MFS superfamily transporter complement(96448..97740) Escherichia fergusonii ATCC 35469 7120546 YP_002381318.1 CDS aroE NC_011740.1 97670 98533 R AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase complement(97670..98533) Escherichia fergusonii ATCC 35469 7120770 YP_002381319.1 CDS EFER_0092 NC_011740.1 98552 100564 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; NADH:flavin oxidoreductase complement(98552..100564) Escherichia fergusonii ATCC 35469 7120771 YP_002381320.1 CDS leuD NC_011740.1 100830 101435 R catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit complement(100830..101435) Escherichia fergusonii ATCC 35469 7123750 YP_002381321.1 CDS leuC NC_011740.1 101446 102846 R dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit complement(101446..102846) Escherichia fergusonii ATCC 35469 7120826 YP_002381322.1 CDS leuB NC_011740.1 102849 103940 R catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase complement(102849..103940) Escherichia fergusonii ATCC 35469 7120825 YP_002381323.1 CDS leuA NC_011740.1 103940 105511 R catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase complement(103940..105511) Escherichia fergusonii ATCC 35469 7120824 YP_002381324.1 CDS leuL NC_011740.1 105601 105687 R involved in attenuation control of the leuABCD operon in leucine biosynthesis; leu operon leader peptide complement(105601..105687) Escherichia fergusonii ATCC 35469 7123228 YP_002381325.1 CDS leuO NC_011740.1 106327 107289 D activator for leuABCD operon; member of LysR family of transcriptional activators; leucine transcriptional activator 106327..107289 Escherichia fergusonii ATCC 35469 7120827 YP_002381326.1 CDS ilvI NC_011740.1 107606 109330 D catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; acetolactate synthase 3 catalytic subunit 107606..109330 Escherichia fergusonii ATCC 35469 7123229 YP_002381327.1 CDS ilvH NC_011740.1 109333 109824 D with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 109333..109824 Escherichia fergusonii ATCC 35469 7120732 YP_002381328.1 CDS fruR NC_011740.1 110005 111009 D binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism; DNA-binding transcriptional regulator FruR 110005..111009 Escherichia fergusonii ATCC 35469 7123743 YP_002381329.1 CDS mraZ NC_011740.1 111603 112061 D MraZ; UPF0040; crystal structure shows similarity to AbrB; cell division protein MraZ 111603..112061 Escherichia fergusonii ATCC 35469 7123572 YP_002381330.1 CDS mraW NC_011740.1 112063 113004 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20042184, 10493123, 2187182, 6350821; Product type e : enzyme; S-adenosyl-methyltransferase MraW 112063..113004 Escherichia fergusonii ATCC 35469 7120964 YP_002381331.1 CDS ftsL NC_011740.1 113001 113366 D membrane bound cell division protein at septum containing leucine zipper motif; cell division protein FtsL 113001..113366 Escherichia fergusonii ATCC 35469 7120963 YP_002381332.1 CDS ftsI NC_011740.1 113382 115148 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91072213, 92202178, 94095121, 9603865, 9614966, 1332942, 1447153, 2198024, 2677607, 2681146, 3049550, 3911028, 6350821; Product type e : enzyme; septal peptidoglycan synthesis transpeptidase 113382..115148 Escherichia fergusonii ATCC 35469 7120149 YP_002381333.1 CDS murE NC_011740.1 115135 116622 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 115135..116622 Escherichia fergusonii ATCC 35469 7123112 YP_002381334.1 CDS murF NC_011740.1 116619 117977 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88273095, 90248455, 91310568, 97128642, 11090285, 2668880, 9166795; Product type e : enzyme; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 116619..117977 Escherichia fergusonii ATCC 35469 7120646 YP_002381335.1 CDS mraY NC_011740.1 117971 119053 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 117971..119053 Escherichia fergusonii ATCC 35469 7120647 YP_002381336.1 CDS murD NC_011740.1 119056 120372 D UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 119056..120372 Escherichia fergusonii ATCC 35469 7123783 YP_002381337.1 CDS ftsW NC_011740.1 120372 121616 D integral membrane protein involved in stabilizing FstZ ring during cell division; cell division protein FtsW 120372..121616 Escherichia fergusonii ATCC 35469 7123196 YP_002381338.1 CDS murG NC_011740.1 121613 122680 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 121613..122680 Escherichia fergusonii ATCC 35469 7123652 YP_002381339.1 CDS murC NC_011740.1 122734 124209 D Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 122734..124209 Escherichia fergusonii ATCC 35469 7120648 YP_002381340.1 CDS ddl NC_011740.1 124202 125122 D D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 124202..125122 Escherichia fergusonii ATCC 35469 7123195 YP_002381341.1 CDS ftsQ NC_011740.1 125124 125954 D involved in septum formation; cell division protein FtsQ 125124..125954 Escherichia fergusonii ATCC 35469 7123547 YP_002381342.1 CDS ftsA NC_011740.1 125951 127213 D ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane; cell division protein FtsA 125951..127213 Escherichia fergusonii ATCC 35469 7123651 YP_002381343.1 CDS ftsZ NC_011740.1 127275 128426 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 127275..128426 Escherichia fergusonii ATCC 35469 7120146 YP_002381344.1 CDS lpxC NC_011740.1 128527 129444 D zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 128527..129444 Escherichia fergusonii ATCC 35469 7120152 YP_002381345.1 CDS secM NC_011740.1 129625 130182 D secM translational pause allows for the initiation of secA translation; SecA regulator SecM 129625..130182 Escherichia fergusonii ATCC 35469 7121201 YP_002381346.1 CDS secA NC_011740.1 130244 132949 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 130244..132949 Escherichia fergusonii ATCC 35469 7121764 YP_002381347.1 CDS mutT NC_011740.1 133012 133410 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10218109, 89264540, 90136514, 91225007, 97444511, 1309939, 2841285, 3033442, 3288626, 7578113, 9063868; Product type e : enzyme; nucleoside triphosphate pyrophosphohydrolase 133012..133410 Escherichia fergusonii ATCC 35469 7121760 YP_002381348.1 CDS yacG NC_011740.1 133506 133700 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12211008, 3033442; zinc-binding protein complement(133506..133700) Escherichia fergusonii ATCC 35469 7123729 YP_002381349.1 CDS yacF NC_011740.1 133710 134453 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(133710..134453) Escherichia fergusonii ATCC 35469 7123474 YP_002381350.1 CDS coaE NC_011740.1 134453 135073 R catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase complement(134453..135073) Escherichia fergusonii ATCC 35469 7122397 YP_002381351.1 CDS guaC NC_011740.1 135299 136342 D catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; guanosine 5'-monophosphate oxidoreductase 135299..136342 Escherichia fergusonii ATCC 35469 7120910 YP_002381352.1 CDS hofC NC_011740.1 136377 137612 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 96099298, 2904262, 7959070; Product type s : structure; type IV pilin biogenesis protein complement(136377..137612) Escherichia fergusonii ATCC 35469 7120624 YP_002381353.1 CDS hofB NC_011740.1 137569 138954 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(137569..138954) Escherichia fergusonii ATCC 35469 7122206 YP_002381354.1 CDS ppdD NC_011740.1 138964 139401 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 20100782, 20271862, 96099298, 7959070; Product type ps : structure; major pilin subunit complement(138964..139401) Escherichia fergusonii ATCC 35469 7124000 YP_002381355.1 CDS nadC NC_011740.1 139615 140508 R catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; quinolinate phosphoribosyltransferase complement(139615..140508) Escherichia fergusonii ATCC 35469 7120109 YP_002381356.1 CDS ampD NC_011740.1 140596 141147 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90113890, 95047240, 2607970, 7959070; Product type e : enzyme; N-acetyl-anhydromuranmyl-L-alanine amidase 140596..141147 Escherichia fergusonii ATCC 35469 7120659 YP_002381357.1 CDS ampE NC_011740.1 141144 141998 D involved in regulation of beta-lactamase; signaling protein; regulatory protein AmpE 141144..141998 Escherichia fergusonii ATCC 35469 7120512 YP_002381358.1 CDS aroP NC_011740.1 142038 143411 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1104763, 90174991, 9150230; Product type t : transporter; aromatic amino acid transporter complement(142038..143411) Escherichia fergusonii ATCC 35469 7120513 YP_002381359.1 CDS pdhR NC_011740.1 144001 144765 D activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; transcriptional regulator PdhR 144001..144765 Escherichia fergusonii ATCC 35469 7120553 YP_002381360.1 CDS EFER_0134 NC_011740.1 144762 144944 R Evidence 6 : Doubtful CDS; hypothetical protein complement(144762..144944) Escherichia fergusonii ATCC 35469 7122149 YP_002381361.1 CDS aceE NC_011740.1 144926 147589 D E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 144926..147589 Escherichia fergusonii ATCC 35469 7120772 YP_002381362.1 CDS aceF NC_011740.1 147604 149496 D E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase 147604..149496 Escherichia fergusonii ATCC 35469 7122257 YP_002381363.1 CDS lpd NC_011740.1 149704 151128 D E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 149704..151128 Escherichia fergusonii ATCC 35469 7122258 YP_002381364.1 CDS yacH NC_011740.1 151199 153055 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(151199..153055) Escherichia fergusonii ATCC 35469 7120849 YP_002381365.1 CDS acnB NC_011740.1 153410 156007 D catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 153410..156007 Escherichia fergusonii ATCC 35469 7122398 YP_002381366.1 CDS yacL NC_011740.1 156204 156566 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2666401, 7567469; hypothetical protein 156204..156566 Escherichia fergusonii ATCC 35469 7122261 YP_002381367.1 CDS speD NC_011740.1 156604 157398 R S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase complement(156604..157398) Escherichia fergusonii ATCC 35469 7122399 YP_002381368.1 CDS speE NC_011740.1 157414 158280 R catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase complement(157414..158280) Escherichia fergusonii ATCC 35469 7121804 YP_002381369.1 CDS yacC NC_011740.1 158386 158904 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2666401; hypothetical protein complement(158386..158904) Escherichia fergusonii ATCC 35469 7121805 YP_002381370.1 CDS cueO NC_011740.1 158899 160449 D laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase 158899..160449 Escherichia fergusonii ATCC 35469 7122396 YP_002381371.1 CDS gcd NC_011740.1 160496 162886 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10359647, 11604400, 14612441, 91035240, 93123180, 93286127; Product type e : enzyme; glucose dehydrogenase complement(160496..162886) Escherichia fergusonii ATCC 35469 7122826 YP_002381372.1 CDS hpt NC_011740.1 163092 163628 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 13808016, 339828, 6787390, 6801015, 12070315; Product type e : enzyme; hypoxanthine phosphoribosyltransferase 163092..163628 Escherichia fergusonii ATCC 35469 7120176 YP_002381373.1 CDS can NC_011740.1 163669 164331 R catalyzes the interconversion of bicarbonate and carbon dioxide; carbonic anhydrase complement(163669..164331) Escherichia fergusonii ATCC 35469 7122220 YP_002381374.1 CDS yadG NC_011740.1 164440 165366 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter ATP-binding protein 164440..165366 Escherichia fergusonii ATCC 35469 7120857 YP_002381375.1 CDS yadH NC_011740.1 165363 166133 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10474187; Product type pt : transporter; ABC transporter membrane protein 165363..166133 Escherichia fergusonii ATCC 35469 7122402 YP_002381376.1 CDS yadI NC_011740.1 166238 166678 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; PTS system transporter subunit IIA 166238..166678 Escherichia fergusonii ATCC 35469 7122403 YP_002381377.1 CDS yadE NC_011740.1 166735 167961 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; polysaccharide deacetylase 166735..167961 Escherichia fergusonii ATCC 35469 7122404 YP_002381378.1 CDS panD NC_011740.1 167965 168345 R Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase complement(167965..168345) Escherichia fergusonii ATCC 35469 7122401 YP_002381379.1 CDS yadD NC_011740.1 168619 169551 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11319082; Product type pe : enzyme; transposase 168619..169551 Escherichia fergusonii ATCC 35469 7123498 YP_002381380.1 CDS panC NC_011740.1 169917 170768 R catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase complement(169917..170768) Escherichia fergusonii ATCC 35469 7124033 YP_002381381.1 CDS panB NC_011740.1 170780 171574 R catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase complement(170780..171574) Escherichia fergusonii ATCC 35469 7122553 YP_002381382.1 CDS yadC NC_011740.1 171686 172972 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; fimbrial-like adhesin protein complement(171686..172972) Escherichia fergusonii ATCC 35469 7122552 YP_002381383.1 CDS EFER_0158 NC_011740.1 172997 173593 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; fimbrial-like adhesin protein complement(172997..173593) Escherichia fergusonii ATCC 35469 7124032 YP_002381384.1 CDS yadL NC_011740.1 173619 174233 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; fimbrial-like adhesin protein complement(173619..174233) Escherichia fergusonii ATCC 35469 7120773 YP_002381385.1 CDS yadM NC_011740.1 174239 174814 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; fimbrial-like adhesin protein complement(174239..174814) Escherichia fergusonii ATCC 35469 7124034 YP_002381386.1 CDS htrE NC_011740.1 174830 177427 R similar to the fimbrial usher protein PapC; outer membrane usher protein complement(174830..177427) Escherichia fergusonii ATCC 35469 7122405 YP_002381387.1 CDS ecpD NC_011740.1 177463 178203 R Evidence 2b : Function of strongly homologous gene; PubMedId : 93352405, 8102362, 15561151; Product type f : factor; chaperone protein EcpD complement(177463..178203) Escherichia fergusonii ATCC 35469 7124003 YP_002381388.1 CDS yadN NC_011740.1 178300 178884 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; fimbrial-like adhesin protein complement(178300..178884) Escherichia fergusonii ATCC 35469 7122936 YP_002381389.1 CDS folK NC_011740.1 179239 179718 R catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase complement(179239..179718) Escherichia fergusonii ATCC 35469 7123475 YP_002381390.1 CDS pcnB NC_011740.1 179715 181133 R Polymerase that creates the 3' poly(A) tail found in some mRNA's; poly(A) polymerase I complement(179715..181133) Escherichia fergusonii ATCC 35469 7123004 YP_002381391.1 CDS yadB NC_011740.1 181172 182080 R this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase complement(181172..182080) Escherichia fergusonii ATCC 35469 7122566 YP_002381392.1 CDS dksA NC_011740.1 182134 182589 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15294157, 90202727, 2013578, 9298646, 9600841; Product type r : regulator; RNA polymerase-binding transcription factor complement(182134..182589) Escherichia fergusonii ATCC 35469 7122400 YP_002381393.1 CDS sfsA NC_011740.1 182768 183472 R Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A complement(182768..183472) Escherichia fergusonii ATCC 35469 7122906 YP_002381394.1 CDS ligT NC_011740.1 183487 184242 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; 2'-5' RNA ligase complement(183487..184242) Escherichia fergusonii ATCC 35469 7121775 YP_002381395.1 CDS hrpB NC_011740.1 184091 186520 D similar in sequence to the ATP-dependent RNA helicase HrpA; ATP-dependent RNA helicase HrpB 184091..186520 Escherichia fergusonii ATCC 35469 7123760 YP_002381396.1 CDS mrcB NC_011740.1 186614 189148 D bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell; penicillin-binding protein 1b 186614..189148 Escherichia fergusonii ATCC 35469 7122221 YP_002381397.1 CDS fhuA NC_011740.1 189368 191557 D involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein; ferrichrome outer membrane transporter 189368..191557 Escherichia fergusonii ATCC 35469 7123249 YP_002381398.1 CDS fhuC NC_011740.1 191608 192405 D part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; iron-hydroxamate transporter ATP-binding subunit 191608..192405 Escherichia fergusonii ATCC 35469 7120012 YP_002381399.1 CDS fhuD NC_011740.1 192405 193295 D Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores; iron-hydroxamate transporter substrate-binding subunit 192405..193295 Escherichia fergusonii ATCC 35469 7120014 YP_002381400.1 CDS fhuB NC_011740.1 193292 195274 D part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome; iron-hydroxamate transporter permease subunit 193292..195274 Escherichia fergusonii ATCC 35469 7120015 YP_002381401.1 CDS hemL NC_011740.1 195309 196589 R Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase complement(195309..196589) Escherichia fergusonii ATCC 35469 7120013 YP_002381402.1 CDS clcA NC_011740.1 196814 198235 D Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein 196814..198235 Escherichia fergusonii ATCC 35469 7123995 YP_002381403.1 CDS yadR NC_011740.1 198317 198661 D essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 198317..198661 Escherichia fergusonii ATCC 35469 7120901 YP_002381404.1 CDS EFER_0180 NC_011740.1 198722 199351 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein complement(198722..199351) Escherichia fergusonii ATCC 35469 7122406 YP_002381405.1 CDS btuF NC_011740.1 199387 200214 R solute binding component of the vitamin B12 transport system BtuCDF; vitamin B12-transporter protein BtuF complement(199387..200214) Escherichia fergusonii ATCC 35469 7120774 YP_002381406.1 CDS pfs NC_011740.1 200180 200878 R enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase complement(200180..200878) Escherichia fergusonii ATCC 35469 7123360 YP_002381407.1 CDS dgt NC_011740.1 200961 202478 D forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase 200961..202478 Escherichia fergusonii ATCC 35469 7124065 YP_002381408.1 CDS degP NC_011740.1 202608 204032 D protease Do; required at high temperature; degrades damaged proteins; serine endoprotease 202608..204032 Escherichia fergusonii ATCC 35469 7123551 YP_002381409.1 CDS cdaR NC_011740.1 204190 205347 D regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization; carbohydrate diacid transcriptional activator CdaR 204190..205347 Escherichia fergusonii ATCC 35469 7123548 YP_002381410.1 CDS yaeH NC_011740.1 205462 205848 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(205462..205848) Escherichia fergusonii ATCC 35469 7120873 YP_002381411.1 CDS yaeI NC_011740.1 206006 206821 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; phosphodiesterase YaeI complement(206006..206821) Escherichia fergusonii ATCC 35469 7122409 YP_002381412.1 CDS dapD NC_011740.1 206872 207696 R catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase complement(206872..207696) Escherichia fergusonii ATCC 35469 7122410 YP_002381413.1 CDS glnD NC_011740.1 207727 210399 R catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase complement(207727..210399) Escherichia fergusonii ATCC 35469 7123546 YP_002381414.1 CDS map NC_011740.1 210461 211255 R catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase complement(210461..211255) Escherichia fergusonii ATCC 35469 7120195 YP_002381415.1 CDS rpsB NC_011740.1 211623 212348 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 211623..212348 Escherichia fergusonii ATCC 35469 7123955 YP_002381416.1 CDS tsf NC_011740.1 212483 213334 D EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 212483..213334 Escherichia fergusonii ATCC 35469 7121127 YP_002381417.1 CDS pyrH NC_011740.1 213481 214206 D Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 213481..214206 Escherichia fergusonii ATCC 35469 7122174 YP_002381418.1 CDS frr NC_011740.1 214356 214913 D Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 214356..214913 Escherichia fergusonii ATCC 35469 7122337 YP_002381419.1 CDS dxr NC_011740.1 215006 216202 D catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 215006..216202 Escherichia fergusonii ATCC 35469 7123013 YP_002381420.1 CDS ispU NC_011740.1 216388 217149 D catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 216388..217149 Escherichia fergusonii ATCC 35469 7123556 YP_002381421.1 CDS cdsA NC_011740.1 217162 218019 D catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate; CDP-diglyceride synthase 217162..218019 Escherichia fergusonii ATCC 35469 7120796 YP_002381422.1 CDS yaeL NC_011740.1 218031 219383 D catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; zinc metallopeptidase RseP 218031..219383 Escherichia fergusonii ATCC 35469 7120876 YP_002381423.1 CDS yaeT NC_011740.1 219415 221823 D part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; outer membrane protein assembly factor YaeT 219415..221823 Escherichia fergusonii ATCC 35469 7122412 YP_002381424.1 CDS hlpA NC_011740.1 221947 222432 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15101556, 90201355, 97032152, 99386928, 1987124, 2843433, 9298646, 2167239; Product type f : factor; periplasmic chaperone 221947..222432 Escherichia fergusonii ATCC 35469 7123477 YP_002381425.1 CDS lpxD NC_011740.1 222436 223461 D adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 222436..223461 Escherichia fergusonii ATCC 35469 7122204 YP_002381426.1 CDS fabZ NC_011740.1 223566 224021 D in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 223566..224021 Escherichia fergusonii ATCC 35469 7121202 YP_002381427.1 CDS lpxA NC_011740.1 224025 224813 D catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 224025..224813 Escherichia fergusonii ATCC 35469 7123625 YP_002381428.1 CDS lpxB NC_011740.1 224813 225961 D catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 224813..225961 Escherichia fergusonii ATCC 35469 7121199 YP_002381429.1 CDS rnhB NC_011740.1 225958 226554 D RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 225958..226554 Escherichia fergusonii ATCC 35469 7121200 YP_002381430.1 CDS dnaE NC_011740.1 226591 230073 D catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 226591..230073 Escherichia fergusonii ATCC 35469 7121428 YP_002381431.1 CDS accA NC_011740.1 230086 231045 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 230086..231045 Escherichia fergusonii ATCC 35469 7122910 YP_002381432.1 CDS ldcC NC_011740.1 231143 233284 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 97480927, 98195734, 98357244, 9226257, 9723924; Product type e : enzyme; lysine decarboxylase 2 231143..233284 Escherichia fergusonii ATCC 35469 7122253 YP_002381433.1 CDS yaeR NC_011740.1 233341 233730 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 233341..233730 Escherichia fergusonii ATCC 35469 7120818 YP_002381434.1 CDS tilS NC_011740.1 233795 235093 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase; tRNA(Ile)-lysidine synthetase 233795..235093 Escherichia fergusonii ATCC 35469 7123476 YP_002381435.1 CDS rof NC_011740.1 235142 235396 R Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination; Rho-binding antiterminator complement(235142..235396) Escherichia fergusonii ATCC 35469 7123985 YP_002381436.1 CDS yaeP NC_011740.1 235389 235589 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(235389..235589) Escherichia fergusonii ATCC 35469 7121433 YP_002381437.1 CDS yaeQ NC_011740.1 235755 236300 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 235755..236300 Escherichia fergusonii ATCC 35469 7122413 YP_002381438.1 CDS yaeJ NC_011740.1 236297 236719 D Evidence 4 : Homologs of previously reported genes of unknown function; peptidyl-tRNA hydrolase domain-containing protein 236297..236719 Escherichia fergusonii ATCC 35469 7122414 YP_002381439.1 CDS nlpE NC_011740.1 236733 237443 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11830644, 95362641, 95362642; Product type lp : lipoprotein; lipoprotein 236733..237443 Escherichia fergusonii ATCC 35469 7122411 YP_002381440.1 CDS yaeF NC_011740.1 237599 238423 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; hypothetical protein complement(237599..238423) Escherichia fergusonii ATCC 35469 7119652 YP_002381441.1 CDS proS NC_011740.1 238476 240194 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(238476..240194) Escherichia fergusonii ATCC 35469 7122408 YP_002381442.1 CDS yaeB NC_011740.1 240305 241012 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(240305..241012) Escherichia fergusonii ATCC 35469 7123110 YP_002381443.1 CDS rcsF NC_011740.1 241009 241413 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 93094132; Product type pr : regulator; outer membrane lipoprotein complement(241009..241413) Escherichia fergusonii ATCC 35469 7122407 YP_002381444.1 CDS metQ NC_011740.1 241531 242346 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12169620, 12218041, 12819857, 1459951; Product type t : transporter; DL-methionine transporter substrate-binding subunit complement(241531..242346) Escherichia fergusonii ATCC 35469 7122355 YP_002381445.1 CDS metI NC_011740.1 242386 243039 R part of the MetNIQ methionine uptake system; DL-methionine transporter permease complement(242386..243039) Escherichia fergusonii ATCC 35469 7120925 YP_002381446.1 CDS metN NC_011740.1 243032 244063 R part of the metNIQ transport system for methionine; DL-methionine transporter ATP-binding subunit complement(243032..244063) Escherichia fergusonii ATCC 35469 7120921 YP_002381447.1 CDS gmhB NC_011740.1 244251 244823 D Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate; D,D-heptose 1,7-bisphosphate phosphatase 244251..244823 Escherichia fergusonii ATCC 35469 7120924 YP_002381448.1 CDS dkgB NC_011740.1 250591 251394 D catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; 2,5-diketo-D-gluconate reductase B 250591..251394 Escherichia fergusonii ATCC 35469 7120041 YP_002381449.1 CDS yafC NC_011740.1 251391 252305 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator complement(251391..252305) Escherichia fergusonii ATCC 35469 7122905 YP_002381450.1 CDS yafD NC_011740.1 252546 253346 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1663890; hypothetical protein 252546..253346 Escherichia fergusonii ATCC 35469 7122415 YP_002381451.1 CDS yafE NC_011740.1 253424 254194 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; S-adenosyl-L-methionine-dependent methyltransferase 253424..254194 Escherichia fergusonii ATCC 35469 7122416 YP_002381452.1 CDS mltD NC_011740.1 254242 255600 R catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall; membrane-bound lytic murein transglycosylase D complement(254242..255600) Escherichia fergusonii ATCC 35469 7122417 YP_002381453.1 CDS gloB NC_011740.1 255672 256427 R catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione; hydroxyacylglutathione hydrolase complement(255672..256427) Escherichia fergusonii ATCC 35469 7120940 YP_002381454.1 CDS yafS NC_011740.1 256461 257183 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; S-adenosyl-L-methionine-dependent methyltransferase 256461..257183 Escherichia fergusonii ATCC 35469 7123661 YP_002381455.1 CDS rnhA NC_011740.1 257180 257647 R An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H complement(257180..257647) Escherichia fergusonii ATCC 35469 7124036 YP_002381456.1 CDS dnaQ NC_011740.1 257712 258443 D 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 257712..258443 Escherichia fergusonii ATCC 35469 7121427 YP_002381457.1 CDS yafV NC_011740.1 258751 259521 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8526497; Product type pe : enzyme; hypothetical protein complement(258751..259521) Escherichia fergusonii ATCC 35469 7120049 YP_002381458.1 CDS ivy NC_011740.1 259675 260148 D inactivates vertebrate C-type lysozyme; C-lysozyme inhibitor 259675..260148 Escherichia fergusonii ATCC 35469 7122424 YP_002381459.1 CDS fadE NC_011740.1 260191 262635 R functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase complement(260191..262635) Escherichia fergusonii ATCC 35469 7120798 YP_002381460.1 CDS gmhA NC_011740.1 262875 263453 D catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 262875..263453 Escherichia fergusonii ATCC 35469 7119988 YP_002381461.1 CDS yafJ NC_011740.1 263658 264425 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; class-II glutamine amidotransferase 263658..264425 Escherichia fergusonii ATCC 35469 7120848 YP_002381462.1 CDS yafK NC_011740.1 264396 265136 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(264396..265136) Escherichia fergusonii ATCC 35469 7122418 YP_002381463.1 CDS yafL NC_011740.1 265428 266186 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hydrolase 265428..266186 Escherichia fergusonii ATCC 35469 7122419 YP_002381464.1 CDS argA NC_011740.1 266249 267580 R catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase complement(266249..267580) Escherichia fergusonii ATCC 35469 7122420 YP_002381465.1 CDS amiC NC_011740.1 267812 269065 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12787347, 21348478; Product type e : enzyme; N-acetylmuramoyl-L-alanine amidase 267812..269065 Escherichia fergusonii ATCC 35469 7120536 YP_002381466.1 CDS mltA NC_011740.1 269645 270742 D membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A 269645..270742 Escherichia fergusonii ATCC 35469 7124006 YP_002381467.1 CDS ygdL NC_011740.1 270819 271625 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 270819..271625 Escherichia fergusonii ATCC 35469 7120938 YP_002381468.1 CDS ygdK NC_011740.1 271676 272119 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; Fe-S metabolism protein complement(271676..272119) Escherichia fergusonii ATCC 35469 7123877 YP_002381469.1 CDS csdA NC_011740.1 272119 273324 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15148362, 9278392, 10739946, 10829016; Product type e : enzyme; cysteine sulfinate desulfinase complement(272119..273324) Escherichia fergusonii ATCC 35469 7121503 YP_002381470.1 CDS ygdI NC_011740.1 273513 273740 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 273513..273740 Escherichia fergusonii ATCC 35469 7122810 YP_002381471.1 CDS gcvA NC_011740.1 274091 275008 D Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence; DNA-binding transcriptional activator GcvA 274091..275008 Escherichia fergusonii ATCC 35469 7120179 YP_002381472.1 CDS ygdD NC_011740.1 275027 275422 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 7704273; Product type pm : membrane component; hypothetical protein 275027..275422 Escherichia fergusonii ATCC 35469 7120178 YP_002381473.1 CDS ygdE NC_011740.1 275415 276515 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 21188420, 7704273; Product type pe : enzyme; RNA 2'-O-ribose methyltransferase 275415..276515 Escherichia fergusonii ATCC 35469 7123876 YP_002381474.1 CDS xni NC_011740.1 276569 277414 R has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups; exonuclease IX complement(276569..277414) Escherichia fergusonii ATCC 35469 7121500 YP_002381475.1 CDS sdaB NC_011740.1 277436 278803 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91193203, 93215657, 8385012; Product type e : enzyme; L-serine deaminase II complement(277436..278803) Escherichia fergusonii ATCC 35469 7119975 YP_002381476.1 CDS sdaC NC_011740.1 278861 280150 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8752353, 8026499; Product type pt : transporter; serine transporter complement(278861..280150) Escherichia fergusonii ATCC 35469 7121754 YP_002381477.1 CDS ygdH NC_011740.1 280702 282066 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(280702..282066) Escherichia fergusonii ATCC 35469 7121755 YP_002381478.1 CDS queF NC_011740.1 282182 283030 R catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase complement(282182..283030) Escherichia fergusonii ATCC 35469 7121501 YP_002381479.1 CDS syd NC_011740.1 283099 283644 D SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function; SecY interacting protein Syd 283099..283644 Escherichia fergusonii ATCC 35469 7123465 YP_002381480.1 CDS EFER_0269 NC_011740.1 284069 284602 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 284069..284602 Escherichia fergusonii ATCC 35469 7123539 YP_002381481.1 CDS truC NC_011740.1 284602 285384 D catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp; tRNA pseudouridine synthase C 284602..285384 Escherichia fergusonii ATCC 35469 7120775 YP_002381482.1 CDS yqcA NC_011740.1 285402 285848 D An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 285402..285848 Escherichia fergusonii ATCC 35469 7122170 YP_002381483.1 CDS EFER_0272 NC_011740.1 285945 286943 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(285945..286943) Escherichia fergusonii ATCC 35469 7119721 YP_002381484.1 CDS EFER_0273 NC_011740.1 286944 288446 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(286944..288446) Escherichia fergusonii ATCC 35469 7120776 YP_002381485.1 CDS EFER_0274 NC_011740.1 288471 288950 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(288471..288950) Escherichia fergusonii ATCC 35469 7120777 YP_002381486.1 CDS gudX NC_011740.1 289716 291056 D Evidence 2b : Function of strongly homologous gene; PubMedId : 9772162; Product type e : enzyme; glucarate dehydratase 289716..291056 Escherichia fergusonii ATCC 35469 7123219 YP_002381487.1 CDS gudD NC_011740.1 291077 292417 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20233700, 9772162, 10762278, 13971911; Product type e : enzyme; (D)-glucarate dehydratase 1 291077..292417 Escherichia fergusonii ATCC 35469 7120626 YP_002381488.1 CDS EFER_0277 NC_011740.1 292506 293660 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; glycerate kinase 292506..293660 Escherichia fergusonii ATCC 35469 7120625 YP_002381489.1 CDS barA NC_011740.1 293775 296531 R part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system; hybrid sensory histidine kinase BarA complement(293775..296531) Escherichia fergusonii ATCC 35469 7120778 YP_002381490.1 CDS rumA NC_011740.1 296588 297886 D in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase 296588..297886 Escherichia fergusonii ATCC 35469 7121644 YP_002381491.1 CDS relA NC_011740.1 297937 300171 D (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP; GDP/GTP pyrophosphokinase 297937..300171 Escherichia fergusonii ATCC 35469 7123277 YP_002381492.1 CDS chpR NC_011740.1 300249 300497 D part of the MazF-MazE toxin-antitoxin system; conteracts MazF; antitoxin MazE 300249..300497 Escherichia fergusonii ATCC 35469 7123859 YP_002381493.1 CDS chpA NC_011740.1 300497 300832 D MazF; endoribonuclease; toxin of the ChpA-ChpR toxin-antitoxin system; toxin ChpA 300497..300832 Escherichia fergusonii ATCC 35469 7123769 YP_002381494.1 CDS mazG NC_011740.1 300903 301694 D functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era; nucleoside triphosphate pyrophosphohydrolase 300903..301694 Escherichia fergusonii ATCC 35469 7123236 YP_002381495.1 CDS pyrG NC_011740.1 301922 303559 D CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 301922..303559 Escherichia fergusonii ATCC 35469 7121235 YP_002381496.1 CDS eno NC_011740.1 303647 304945 D enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 303647..304945 Escherichia fergusonii ATCC 35469 7122336 YP_002381497.1 CDS insG NC_011740.1 305000 306328 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; IS4 transposase; KpLE2 phage-like element complement(305000..306328) Escherichia fergusonii ATCC 35469 7122949 YP_002381498.1 CDS EFER_0287 NC_011740.1 306396 306635 R Evidence 6 : Doubtful CDS; hypothetical protein complement(306396..306635) Escherichia fergusonii ATCC 35469 7123213 YP_002381499.1 CDS EFER_0288 NC_011740.1 306445 307329 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(306445..307329) Escherichia fergusonii ATCC 35469 7120779 YP_002381500.1 CDS EFER_0290 NC_011740.1 307323 308471 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(307323..308471) Escherichia fergusonii ATCC 35469 7123751 YP_002381501.1 CDS ygcG NC_011740.1 308486 309418 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(308486..309418) Escherichia fergusonii ATCC 35469 7120780 YP_002381502.1 CDS EFER_0292 NC_011740.1 309408 310010 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(309408..310010) Escherichia fergusonii ATCC 35469 7121494 YP_002381503.1 CDS ygcF NC_011740.1 310183 310854 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 310183..310854 Escherichia fergusonii ATCC 35469 7120781 YP_002381504.1 CDS EFER_0294 NC_011740.1 311404 311547 D Evidence 6 : Doubtful CDS; hypothetical protein 311404..311547 Escherichia fergusonii ATCC 35469 7121493 YP_002381505.1 CDS EFER_0295 NC_011740.1 312262 312525 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 312262..312525 Escherichia fergusonii ATCC 35469 7123752 YP_002381506.1 CDS ygcM NC_011740.1 312886 313251 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12123838; Product type e : enzyme; 6-pyruvoyl tetrahydrobiopterin synthase complement(312886..313251) Escherichia fergusonii ATCC 35469 7120782 YP_002381507.1 CDS cysJ NC_011740.1 313567 315366 D catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity; sulfite reductase subunit alpha 313567..315366 Escherichia fergusonii ATCC 35469 7121499 YP_002381508.1 CDS cysI NC_011740.1 315366 317078 D hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta 315366..317078 Escherichia fergusonii ATCC 35469 7122852 YP_002381509.1 CDS cysH NC_011740.1 317142 317876 D catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase 317142..317876 Escherichia fergusonii ATCC 35469 7123543 YP_002381510.1 CDS ygcB NC_011740.1 318234 320900 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pe : enzyme; hypothetical protein 318234..320900 Escherichia fergusonii ATCC 35469 7122851 YP_002381511.1 CDS ygcL NC_011740.1 321315 322823 D unknown function; in E. coli this protein is regulated by BaeR, a protein involved in resistance to novobiocin and deoxycholate; hypothetical protein 321315..322823 Escherichia fergusonii ATCC 35469 7121492 YP_002381512.1 CDS ygcK NC_011740.1 322816 323298 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 322816..323298 Escherichia fergusonii ATCC 35469 7123329 YP_002381513.1 CDS ygcJ NC_011740.1 323311 324402 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 323311..324402 Escherichia fergusonii ATCC 35469 7121498 YP_002381514.1 CDS ygcI NC_011740.1 324405 325079 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 324405..325079 Escherichia fergusonii ATCC 35469 7121497 YP_002381515.1 CDS ygcH NC_011740.1 325066 325665 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 325066..325665 Escherichia fergusonii ATCC 35469 7121496 YP_002381516.1 CDS ygbT NC_011740.1 325681 326598 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 325681..326598 Escherichia fergusonii ATCC 35469 7121495 YP_002381517.1 CDS ygbF NC_011740.1 326600 326884 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 326600..326884 Escherichia fergusonii ATCC 35469 7121491 YP_002381518.1 CDS EFER_0310 NC_011740.1 327389 327538 R Evidence 6 : Doubtful CDS; hypothetical protein complement(327389..327538) Escherichia fergusonii ATCC 35469 7121490 YP_002381519.1 CDS EFER_0311 NC_011740.1 327519 327635 R hypothetical protein complement(327519..327635) Escherichia fergusonii ATCC 35469 7120783 YP_002381521.1 CDS iap NC_011740.1 328260 329297 R catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3; alkaline phosphatase isozyme conversion aminopeptidase complement(328260..329297) Escherichia fergusonii ATCC 35469 7120784 YP_002381522.1 CDS cysD NC_011740.1 329549 330457 D with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 329549..330457 Escherichia fergusonii ATCC 35469 7120717 YP_002381523.1 CDS cysN NC_011740.1 330459 331886 D may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ; sulfate adenylyltransferase subunit 1 330459..331886 Escherichia fergusonii ATCC 35469 7122848 YP_002381524.1 CDS cysC NC_011740.1 331886 332491 D converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis; adenylylsulfate kinase 331886..332491 Escherichia fergusonii ATCC 35469 7122964 YP_002381525.1 CDS ygbE NC_011740.1 332505 332864 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 332505..332864 Escherichia fergusonii ATCC 35469 7122847 YP_002381526.1 CDS ftsB NC_011740.1 333039 333350 D forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein; cell division protein FtsB 333039..333350 Escherichia fergusonii ATCC 35469 7123875 YP_002381527.1 CDS ispD NC_011740.1 333369 334079 D 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 333369..334079 Escherichia fergusonii ATCC 35469 7120147 YP_002381528.1 CDS ispF NC_011740.1 334079 334558 D catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclo diphosphate synthase 334079..334558 Escherichia fergusonii ATCC 35469 7120792 YP_002381529.1 CDS truD NC_011740.1 334555 335604 D catalyzes the modification of U13 in tRNA(Glu); tRNA pseudouridine synthase D 334555..335604 Escherichia fergusonii ATCC 35469 7123754 YP_002381530.1 CDS surE NC_011740.1 335585 336346 D catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 335585..336346 Escherichia fergusonii ATCC 35469 7122171 YP_002381531.1 CDS pcm NC_011740.1 336340 336966 D catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase 336340..336966 Escherichia fergusonii ATCC 35469 7121968 YP_002381532.1 CDS EFER_0326 NC_011740.1 337084 337299 R Evidence 6 : Doubtful CDS; hypothetical protein complement(337084..337299) Escherichia fergusonii ATCC 35469 7122565 YP_002381533.1 CDS nlpD NC_011740.1 337109 338251 D outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus; lipoprotein NlpD 337109..338251 Escherichia fergusonii ATCC 35469 7120785 YP_002381534.1 CDS rpoS NC_011740.1 338431 339306 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12052558, 14671322, 91294193, 94032222, 94179109, 1437569, 2690013, 8208244, 8475100 -!-9006056; Product type f : factor; RNA polymerase, sigma S (sigma 38) factor 338431..339306 Escherichia fergusonii ATCC 35469 7120760 YP_002381535.1 CDS EFER_0329 NC_011740.1 339427 339867 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15731069; Product type r : regulator; transcriptional regulator hosA complement(339427..339867) Escherichia fergusonii ATCC 35469 7123812 YP_002381536.1 CDS EFER_0330 NC_011740.1 339981 340574 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15979273; Product type e : enzyme; hypothetical protein 339981..340574 Escherichia fergusonii ATCC 35469 7123221 YP_002381537.1 CDS EFER_0331 NC_011740.1 340574 342001 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15979273; Product type e : enzyme; hypothetical protein 340574..342001 Escherichia fergusonii ATCC 35469 7120786 YP_002381538.1 CDS EFER_0332 NC_011740.1 342012 342248 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15979273; Product type e : enzyme; hypothetical protein 342012..342248 Escherichia fergusonii ATCC 35469 7120787 YP_002381539.1 CDS pphB NC_011740.1 342290 342946 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9130712; Product type e : enzyme; serine/threonine-specific protein phosphatase 2 complement(342290..342946) Escherichia fergusonii ATCC 35469 7120788 YP_002381540.1 CDS mutS NC_011740.1 343052 345613 R This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS complement(343052..345613) Escherichia fergusonii ATCC 35469 7120112 YP_002381541.1 CDS eryD NC_011740.1 345852 346805 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10708387, 15805518; Product type r : regulator; Ery operon repressor complement(345852..346805) Escherichia fergusonii ATCC 35469 7120654 YP_002381542.1 CDS eryC NC_011740.1 346832 347944 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10708387, 15805518; Product type e : enzyme; D-erythrulose-phosphate dehydrogenase complement(346832..347944) Escherichia fergusonii ATCC 35469 7119963 YP_002381543.1 CDS eryB NC_011740.1 347775 349310 R in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase complement(347775..349310) Escherichia fergusonii ATCC 35469 7119962 YP_002381544.1 CDS eryA NC_011740.1 349319 350881 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10708387, 15805518; Product type e : enzyme; erythritol kinase complement(349319..350881) Escherichia fergusonii ATCC 35469 7122965 YP_002381545.1 CDS EFER_0339 NC_011740.1 351135 351941 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; lipoprotein 351135..351941 Escherichia fergusonii ATCC 35469 7122963 YP_002381546.1 CDS EFER_0340 NC_011740.1 351938 353482 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; sugar ABC transporter ATP-binding protein 351938..353482 Escherichia fergusonii ATCC 35469 7120789 YP_002381547.1 CDS EFER_0341 NC_011740.1 353479 354555 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; sugar ABC transporter membrane protein 353479..354555 Escherichia fergusonii ATCC 35469 7123753 YP_002381548.1 CDS EFER_0342 NC_011740.1 354642 355592 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; sugar ABC transporter substrate-binding protein 354642..355592 Escherichia fergusonii ATCC 35469 7123868 YP_002381549.1 CDS EFER_0343 NC_011740.1 355597 356532 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator of sugar metabolism, DeoR family 355597..356532 Escherichia fergusonii ATCC 35469 7121566 YP_002381550.1 CDS ygbA NC_011740.1 356678 357067 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 356678..357067 Escherichia fergusonii ATCC 35469 7121567 YP_002381551.1 CDS EFER_0345 NC_011740.1 357088 357516 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; molybdenum-pterin-binding-protein complement(357088..357516) Escherichia fergusonii ATCC 35469 7123328 YP_002381552.1 CDS fhlA NC_011740.1 357548 359638 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20307603, 21557168, 90368529, 92140045, 94018617, 2118503, 2280686; Product type r : regulator; DNA-binding transcriptional activator complement(357548..359638) Escherichia fergusonii ATCC 35469 7121568 YP_002381553.1 CDS hypE NC_011740.1 359786 360754 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91194542, 9485446, 1849603; Product type e : enzyme; carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein complement(359786..360754) Escherichia fergusonii ATCC 35469 7120011 YP_002381554.1 CDS hypD NC_011740.1 360793 361914 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91194542, 92255260, 1849603; Product type f : factor; hydrogenase maturation protein complement(360793..361914) Escherichia fergusonii ATCC 35469 7120715 YP_002381555.1 CDS hypC NC_011740.1 361914 362186 R HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase; hydrogenase assembly chaperone complement(361914..362186) Escherichia fergusonii ATCC 35469 7120714 YP_002381556.1 CDS hypB NC_011740.1 362177 363049 R GTP hydrolase involved in nickel liganding into hydrogenases; hydrogenase nickel incorporation protein HypB complement(362177..363049) Escherichia fergusonii ATCC 35469 7123740 YP_002381557.1 CDS hypA NC_011740.1 363053 363403 R plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein complement(363053..363403) Escherichia fergusonii ATCC 35469 7120713 YP_002381558.1 CDS hycA NC_011740.1 363617 364078 D regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon; formate hydrogenlyase regulatory protein HycA 363617..364078 Escherichia fergusonii ATCC 35469 7120712 YP_002381559.1 CDS hycB NC_011740.1 364221 364832 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90251163, 92215587, 92326636, 2187144; Product type c : carrier; hydrogenase 3, Fe-S subunit 364221..364832 Escherichia fergusonii ATCC 35469 7120702 YP_002381560.1 CDS hycC NC_011740.1 364829 366655 D catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3); formate hydrogenlyase subunit 3 364829..366655 Escherichia fergusonii ATCC 35469 7120703 YP_002381561.1 CDS hycD NC_011740.1 366658 367581 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90251163, 92215587, 92326636; Product type m : membrane component; hydrogenase 3, membrane subunit 366658..367581 Escherichia fergusonii ATCC 35469 7120704 YP_002381562.1 CDS hycE NC_011740.1 367599 369308 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92215587, 92326636, 94170785, 2187144, 8125094; Product type e : enzyme; hydrogenase 3, large subunit 367599..369308 Escherichia fergusonii ATCC 35469 7123737 YP_002381563.1 CDS hycF NC_011740.1 369318 369860 D electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate; formate hydrogenlyase complex iron-sulfur subunit 369318..369860 Escherichia fergusonii ATCC 35469 7120705 YP_002381564.1 CDS hycG NC_011740.1 369860 370627 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90251163, 92215587, 92326636, 2187144; Product type e : enzyme; hydrogenase 3 and formate hydrogenase complex, HycG subunit 369860..370627 Escherichia fergusonii ATCC 35469 7123206 YP_002381565.1 CDS hycH NC_011740.1 370624 371034 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92215587, 92326636, 1625581, 2187144, 7851435; Product type f : factor; hydrogenase-3 maturation protein 370624..371034 Escherichia fergusonii ATCC 35469 7120706 YP_002381566.1 CDS hycI NC_011740.1 371027 371497 D involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE; hydrogenase 3 maturation protease 371027..371497 Escherichia fergusonii ATCC 35469 7120707 YP_002381567.1 CDS ascB NC_011740.1 371656 373080 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88297127, 92334140, 1630307; Product type e : enzyme; cryptic 6-phospho-beta-glucosidase complement(371656..373080) Escherichia fergusonii ATCC 35469 7123207 YP_002381568.1 CDS ascF NC_011740.1 373089 374546 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system cellobiose/arbutin/salicin-specific transporter subunit IIBC complement(373089..374546) Escherichia fergusonii ATCC 35469 7120561 YP_002381569.1 CDS ascG NC_011740.1 374803 375816 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88297127, 92334140, 1630307; Product type r : regulator; DNA-binding transcriptional repressor 374803..375816 Escherichia fergusonii ATCC 35469 7123181 YP_002381570.1 CDS hydN NC_011740.1 375965 376492 D involved in electron transport from formate to hydrogen; electron transport protein HydN 375965..376492 Escherichia fergusonii ATCC 35469 7120562 YP_002381571.1 CDS hypF NC_011740.1 376645 378897 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12377778, 92255260, 8661925; Product type e : enzyme; carbamoyl phosphate phosphatase 376645..378897 Escherichia fergusonii ATCC 35469 7120708 YP_002381572.1 CDS norW NC_011740.1 379024 380157 R catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase; nitric oxide reductase complement(379024..380157) Escherichia fergusonii ATCC 35469 7121685 YP_002381573.1 CDS norV NC_011740.1 380154 381593 R detoxifies nitric oxide using NADH; anaerobic nitric oxide reductase flavorubredoxin complement(380154..381593) Escherichia fergusonii ATCC 35469 7119656 YP_002381574.1 CDS norR NC_011740.1 381780 383294 D Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon; anaerobic nitric oxide reductase transcriptional regulator 381780..383294 Escherichia fergusonii ATCC 35469 7119655 YP_002381575.1 CDS gutQ NC_011740.1 383291 384256 R catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate; D-arabinose 5-phosphate isomerase complement(383291..384256) Escherichia fergusonii ATCC 35469 7119654 YP_002381576.1 CDS mltB NC_011740.1 384510 385595 D membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan; murein hydrolase B 384510..385595 Escherichia fergusonii ATCC 35469 7120627 YP_002381577.1 CDS EFER_0373 NC_011740.1 385634 386131 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(385634..386131) Escherichia fergusonii ATCC 35469 7120939 YP_002381578.1 CDS ygaD NC_011740.1 386056 386553 D Evidence 4 : Homologs of previously reported genes of unknown function; competence damage-inducible protein A 386056..386553 Escherichia fergusonii ATCC 35469 7123889 YP_002381579.1 CDS recA NC_011740.1 386633 387694 D catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 386633..387694 Escherichia fergusonii ATCC 35469 7121481 YP_002381580.1 CDS recX NC_011740.1 387762 388262 D binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 387762..388262 Escherichia fergusonii ATCC 35469 7122358 YP_002381581.1 CDS alaS NC_011740.1 388390 391020 D Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 388390..391020 Escherichia fergusonii ATCC 35469 7121385 YP_002381582.1 CDS csrA NC_011740.1 391255 391440 D affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator 391255..391440 Escherichia fergusonii ATCC 35469 7122291 YP_002381583.1 CDS yqaB NC_011740.1 392897 393463 D YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent; fructose-1-phosphatase 392897..393463 Escherichia fergusonii ATCC 35469 7122243 YP_002381584.1 CDS yqaA NC_011740.1 393460 393888 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 393460..393888 Escherichia fergusonii ATCC 35469 7119719 YP_002381585.1 CDS gshA NC_011740.1 393961 395517 D involved in the first step of glutathione biosynthesis; glutamate--cysteine ligase 393961..395517 Escherichia fergusonii ATCC 35469 7119718 YP_002381586.1 CDS luxS NC_011740.1 395667 396182 D catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase 395667..396182 Escherichia fergusonii ATCC 35469 7120930 YP_002381587.1 CDS EFER_0383 NC_011740.1 396233 397345 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; RNA related enzyme complement(396233..397345) Escherichia fergusonii ATCC 35469 7123284 YP_002381588.1 CDS EFER_0384 NC_011740.1 397342 398049 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(397342..398049) Escherichia fergusonii ATCC 35469 7121569 YP_002381589.1 CDS emrB NC_011740.1 398307 399845 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21450803, 93285984, 94262163, 1409590; Product type t : transporter; multidrug efflux system protein complement(398307..399845) Escherichia fergusonii ATCC 35469 7121570 YP_002381590.1 CDS emrA NC_011740.1 399862 401034 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21450803, 93285984, 94262163, 1409590, 8203018; Product type t : transporter; multidrug efflux system complement(399862..401034) Escherichia fergusonii ATCC 35469 7122946 YP_002381591.1 CDS mprA NC_011740.1 401161 401691 R DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB; transcriptional repressor MprA complement(401161..401691) Escherichia fergusonii ATCC 35469 7123559 YP_002381592.1 CDS ygaH NC_011740.1 401782 402117 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(401782..402117) Escherichia fergusonii ATCC 35469 7120961 YP_002381593.1 CDS ygaZ NC_011740.1 402107 402844 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter complement(402107..402844) Escherichia fergusonii ATCC 35469 7121483 YP_002381594.1 CDS EFER_0390 NC_011740.1 402969 404153 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16000740; Product type pt : transporter; transporter complement(402969..404153) Escherichia fergusonii ATCC 35469 7121489 YP_002381595.1 CDS proX NC_011740.1 404345 405337 R with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine; glycine betaine transporter periplasmic subunit complement(404345..405337) Escherichia fergusonii ATCC 35469 7123342 YP_002381596.1 CDS proW NC_011740.1 405395 406459 R with ProVX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter membrane protein complement(405395..406459) Escherichia fergusonii ATCC 35469 7120137 YP_002381597.1 CDS proV NC_011740.1 406452 407654 R with ProWX is involved in the high-affinity uptake of glycine betaine; glycine betaine transporter ATP-binding subunit complement(406452..407654) Escherichia fergusonii ATCC 35469 7120136 YP_002381598.1 CDS nrdF NC_011740.1 408010 408969 R B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta complement(408010..408969) Escherichia fergusonii ATCC 35469 7120135 YP_002381599.1 CDS nrdE NC_011740.1 408979 411123 R Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha complement(408979..411123) Escherichia fergusonii ATCC 35469 7119661 YP_002381600.1 CDS nrdI NC_011740.1 411096 411506 R in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein complement(411096..411506) Escherichia fergusonii ATCC 35469 7119660 YP_002381601.1 CDS nrdH NC_011740.1 411503 411748 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9218434, 11441020, 8820648; Product type pc : carrier; glutaredoxin-like protein complement(411503..411748) Escherichia fergusonii ATCC 35469 7119664 YP_002381602.1 CDS EFER_0398 NC_011740.1 411957 412388 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(411957..412388) Escherichia fergusonii ATCC 35469 7119663 YP_002381603.1 CDS EFER_0399 NC_011740.1 412476 413810 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; bifunctional protein aminotransaminase/transcriptional regulator, GntR family 412476..413810 Escherichia fergusonii ATCC 35469 7121571 YP_002381604.1 CDS ygaM NC_011740.1 413866 414207 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(413866..414207) Escherichia fergusonii ATCC 35469 7121572 YP_002381605.1 CDS ygaC NC_011740.1 414347 414691 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 7961433; hypothetical protein 414347..414691 Escherichia fergusonii ATCC 35469 7121484 YP_002381606.1 CDS ygaW NC_011740.1 414728 415267 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; inner membrane protein complement(414728..415267) Escherichia fergusonii ATCC 35469 7123873 YP_002381607.1 CDS stpA NC_011740.1 415825 416226 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20485613, 93126121, 9643551, 98132400, 99415935, 1480493, 7961433; Product type r : regulator; DNA binding protein 415825..416226 Escherichia fergusonii ATCC 35469 7121488 YP_002381608.1 CDS ygaP NC_011740.1 416273 416797 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pe : enzyme; hypothetical protein complement(416273..416797) Escherichia fergusonii ATCC 35469 7121952 YP_002381609.1 CDS ygaV NC_011740.1 416807 417106 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator complement(416807..417106) Escherichia fergusonii ATCC 35469 7123874 YP_002381610.1 CDS yqaE NC_011740.1 417289 417447 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 417289..417447 Escherichia fergusonii ATCC 35469 7121487 YP_002381611.1 CDS ygaU NC_011740.1 417531 417980 D Evidence 4 : Homologs of previously reported genes of unknown function; LysM domain/BON superfamily protein 417531..417980 Escherichia fergusonii ATCC 35469 7119720 YP_002381612.1 CDS csiR NC_011740.1 417981 418643 R regulator of gab gene expression; DNA-binding transcriptional regulator CsiR complement(417981..418643) Escherichia fergusonii ATCC 35469 7121486 YP_002381613.1 CDS gabP NC_011740.1 418664 420064 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94127927, 9685361, 8297211; Product type t : transporter; gamma-aminobutyrate transporter complement(418664..420064) Escherichia fergusonii ATCC 35469 7122816 YP_002381614.1 CDS gabT NC_011740.1 420301 421581 R catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase complement(420301..421581) Escherichia fergusonii ATCC 35469 7120159 YP_002381615.1 CDS gabD NC_011740.1 421595 423043 R catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; succinate-semialdehyde dehydrogenase I complement(421595..423043) Escherichia fergusonii ATCC 35469 7120160 YP_002381616.1 CDS ygaF NC_011740.1 423066 424334 R catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase complement(423066..424334) Escherichia fergusonii ATCC 35469 7120158 YP_002381617.1 CDS ygaT NC_011740.1 424354 425331 R in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution; hypothetical protein complement(424354..425331) Escherichia fergusonii ATCC 35469 7121482 YP_002381618.1 CDS yahB NC_011740.1 426370 427302 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator complement(426370..427302) Escherichia fergusonii ATCC 35469 7120025 YP_002381619.1 CDS yahC NC_011740.1 427394 427891 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(427394..427891) Escherichia fergusonii ATCC 35469 7123796 YP_002381620.1 CDS yahD NC_011740.1 428149 428754 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; protein with ankyrin domain 428149..428754 Escherichia fergusonii ATCC 35469 7121042 YP_002381621.1 CDS yahE NC_011740.1 428794 429657 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 428794..429657 Escherichia fergusonii ATCC 35469 7121043 YP_002381622.1 CDS yahF NC_011740.1 429647 431194 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 429647..431194 Escherichia fergusonii ATCC 35469 7121044 YP_002381623.1 CDS yahG NC_011740.1 431194 432612 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 431194..432612 Escherichia fergusonii ATCC 35469 7121045 YP_002381624.1 CDS yahI NC_011740.1 432708 433658 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7711027, 11523892; Product type pe : enzyme; carbamate kinase 432708..433658 Escherichia fergusonii ATCC 35469 7121046 YP_002381625.1 CDS yahJ NC_011740.1 433668 435059 D metallo-dependent hydrolase superfamily; deaminase with metallo-dependent hydrolase domain; deaminase 433668..435059 Escherichia fergusonii ATCC 35469 7121047 YP_002381626.1 CDS yjhP NC_011740.1 435140 435886 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; methyltransferase from phage complement(435140..435886) Escherichia fergusonii ATCC 35469 7121048 YP_002381627.1 CDS yjhX NC_011740.1 435896 436210 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(435896..436210) Escherichia fergusonii ATCC 35469 7122027 YP_002381628.1 CDS EFER_0427 NC_011740.1 437733 438716 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; transaldolase A complement(437733..438716) Escherichia fergusonii ATCC 35469 7121049 YP_002381629.1 CDS EFER_0428 NC_011740.1 438744 439202 R catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B complement(438744..439202) Escherichia fergusonii ATCC 35469 7121573 YP_002381630.1 CDS EFER_0429 NC_011740.1 439460 440950 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; tartrate transporter 439460..440950 Escherichia fergusonii ATCC 35469 7121574 YP_002381631.1 CDS EFER_0430 NC_011740.1 440952 442706 D in some organisms the DhaK and DhaL subunits are encoded by separate genes; in others they are fused; functions along with DhaM to phosphorylate dihydroxyacetone; dihydroxyacetone kinase 440952..442706 Escherichia fergusonii ATCC 35469 7121575 YP_002381632.1 CDS EFER_0431 NC_011740.1 442697 443488 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; triosephosphate isomerase 442697..443488 Escherichia fergusonii ATCC 35469 7121576 YP_002381633.1 CDS EFER_0432 NC_011740.1 443485 444333 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; sugar phosphate isomerase/epimerase-like protein 443485..444333 Escherichia fergusonii ATCC 35469 7123890 YP_002381634.1 CDS EFER_0433 NC_011740.1 444290 445180 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; hypothetical protein 444290..445180 Escherichia fergusonii ATCC 35469 7121577 YP_002381635.1 CDS EFER_0434 NC_011740.1 445265 446266 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator 445265..446266 Escherichia fergusonii ATCC 35469 7123891 YP_002381636.1 CDS EFER_0435 NC_011740.1 446452 446595 D Evidence 6 : Doubtful CDS; hypothetical protein 446452..446595 Escherichia fergusonii ATCC 35469 7121578 YP_002381637.1 CDS EFER_0436 NC_011740.1 446547 446879 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 446547..446879 Escherichia fergusonii ATCC 35469 7121579 YP_002381638.1 CDS EFER_0437 NC_011740.1 446952 447194 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7665482; Product type e : enzyme; Virulence protein msgA, DinI-like family complement(446952..447194) Escherichia fergusonii ATCC 35469 7123343 YP_002381639.1 CDS EFER_0438 NC_011740.1 447701 447853 R Evidence 6 : Doubtful CDS; Product type h : extrachromosomal origin; hypothetical protein complement(447701..447853) Escherichia fergusonii ATCC 35469 7121580 YP_002381640.1 CDS EFER_0439 NC_011740.1 448078 448296 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(448078..448296) Escherichia fergusonii ATCC 35469 7121581 YP_002381641.1 CDS EFER_0440 NC_011740.1 448502 450835 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3309336; Product type e : enzyme; phage DNA primase complement(448502..450835) Escherichia fergusonii ATCC 35469 7123344 YP_002381642.1 CDS EFER_0441 NC_011740.1 450850 451170 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(450850..451170) Escherichia fergusonii ATCC 35469 7121582 YP_002381643.1 CDS EFER_0442 NC_011740.1 451306 451761 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(451306..451761) Escherichia fergusonii ATCC 35469 7121583 YP_002381644.1 CDS EFER_0443 NC_011740.1 451754 452041 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 6095206; Product type h : extrachromosomal origin; derepression protein complement(451754..452041) Escherichia fergusonii ATCC 35469 7123892 YP_002381645.1 CDS cI NC_011740.1 452034 452447 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 6095206; Product type h : extrachromosomal origin; regulator protein cI complement(452034..452447) Escherichia fergusonii ATCC 35469 7121584 YP_002381646.1 CDS EFER_0445 NC_011740.1 452630 452896 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; hypothetical protein complement(452630..452896) Escherichia fergusonii ATCC 35469 7120891 YP_002381647.1 CDS EFER_0446 NC_011740.1 453384 454184 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7643390, 3295254; Product type h : extrachromosomal origin; glycoprotein 3 453384..454184 Escherichia fergusonii ATCC 35469 7121585 YP_002381648.1 CDS EFER_0447 NC_011740.1 454181 454681 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; transactivation protein 454181..454681 Escherichia fergusonii ATCC 35469 7123893 YP_002381649.1 CDS EFER_0448 NC_011740.1 454755 455327 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3295254, 2193910; Product type h : extrachromosomal origin; Polarity suppression protein 454755..455327 Escherichia fergusonii ATCC 35469 7121586 YP_002381650.1 CDS EFER_0449 NC_011740.1 455527 457977 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(455527..457977) Escherichia fergusonii ATCC 35469 7121587 YP_002381651.1 CDS int NC_011740.1 458001 459200 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; phage integrase complement(458001..459200) Escherichia fergusonii ATCC 35469 7123894 YP_002381653.1 CDS smpB NC_011740.1 459964 460446 R binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein complement(459964..460446) Escherichia fergusonii ATCC 35469 7121588 YP_002381654.1 CDS yfjG NC_011740.1 460578 461054 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 460578..461054 Escherichia fergusonii ATCC 35469 7123376 YP_002381655.1 CDS yfjF NC_011740.1 461044 461334 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 461044..461334 Escherichia fergusonii ATCC 35469 7121480 YP_002381656.1 CDS smpA NC_011740.1 461394 461735 R Evidence 2b : Function of strongly homologous gene; PubMedId : 2045357; Product type lp : lipoprotein; hypothetical protein complement(461394..461735) Escherichia fergusonii ATCC 35469 7123327 YP_002381657.1 CDS recN NC_011740.1 461884 463545 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87259985, 91355307, 95058623, 3037486; Product type cp : cell process; recombination and repair protein complement(461884..463545) Escherichia fergusonii ATCC 35469 7121795 YP_002381658.1 CDS ppnK NC_011740.1 463631 465259 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16511117, 16233126; Product type e : enzyme; inorganic polyphosphate/ATP-NAD kinase complement(463631..465259) Escherichia fergusonii ATCC 35469 7121382 YP_002381659.1 CDS grpE NC_011740.1 464174 465226 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12639955, 1826368, 3045760; Product type f : factor; heat shock protein HSP70 cofactor 464174..465226 Escherichia fergusonii ATCC 35469 7120115 YP_002381660.1 CDS yfjD NC_011740.1 465281 466477 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(465281..466477) Escherichia fergusonii ATCC 35469 7120617 YP_002381661.1 CDS ypjD NC_011740.1 466588 467454 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(466588..467454) Escherichia fergusonii ATCC 35469 7123326 YP_002381662.1 CDS ffh NC_011740.1 467546 468907 D with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins; signal recognition particle protein 467546..468907 Escherichia fergusonii ATCC 35469 7123582 YP_002381663.1 CDS rpsP NC_011740.1 469044 469292 D binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 469044..469292 Escherichia fergusonii ATCC 35469 7120009 YP_002381664.1 CDS rimM NC_011740.1 469311 469859 D Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 469311..469859 Escherichia fergusonii ATCC 35469 7121137 YP_002381665.1 CDS trmD NC_011740.1 469890 470657 D methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 469890..470657 Escherichia fergusonii ATCC 35469 7121414 YP_002381666.1 CDS rplS NC_011740.1 470699 471046 D this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 470699..471046 Escherichia fergusonii ATCC 35469 7122161 YP_002381667.1 CDS EFER_0467 NC_011740.1 471249 471623 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(471249..471623) Escherichia fergusonii ATCC 35469 7121106 YP_002381668.1 CDS aroF NC_011740.1 471839 472909 D catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 471839..472909 Escherichia fergusonii ATCC 35469 7123345 YP_002381669.1 CDS tyrA NC_011740.1 472920 474041 D catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis; bifunctional chorismate mutase/prephenate dehydrogenase 472920..474041 Escherichia fergusonii ATCC 35469 7120548 YP_002381670.1 CDS pheA NC_011740.1 474084 475244 R catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; bifunctional chorismate mutase/prephenate dehydratase complement(474084..475244) Escherichia fergusonii ATCC 35469 7122612 YP_002381672.1 CDS yfiA NC_011740.1 475495 475839 R associated with 30S ribosomal subunit; interferes with translation elongation; translation inhibitor protein RaiA complement(475495..475839) Escherichia fergusonii ATCC 35469 7122592 YP_002381673.1 CDS yfiO NC_011740.1 476107 476844 R with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline; outer membrane protein assembly complex subunit YfiO complement(476107..476844) Escherichia fergusonii ATCC 35469 7123325 YP_002381674.1 CDS rluD NC_011740.1 476979 477959 D responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase D 476979..477959 Escherichia fergusonii ATCC 35469 7121477 YP_002381675.1 CDS yfiH NC_011740.1 477956 478687 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1906060, 2066329; hypothetical protein 477956..478687 Escherichia fergusonii ATCC 35469 7123317 YP_002381676.1 CDS clpB NC_011740.1 478817 481390 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14550559, 14640692, 91294166, 93015925, 93388583, 99428468; Product type f : factor; protein disaggregation chaperone 478817..481390 Escherichia fergusonii ATCC 35469 7121179 YP_002381677.1 CDS kgtP NC_011740.1 487175 488473 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91219460, 1709493, 2053984, 2118499, 2190187, 8419306; Product type t : transporter; alpha-ketoglutarate transporter 487175..488473 Escherichia fergusonii ATCC 35469 7120510 YP_002381678.1 CDS yfiM NC_011740.1 488470 488742 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(488470..488742) Escherichia fergusonii ATCC 35469 7120814 YP_002381679.1 CDS pssA NC_011740.1 488839 490194 R catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome; phosphatidylserine synthase complement(488839..490194) Escherichia fergusonii ATCC 35469 7121476 YP_002381680.1 CDS yfiQ NC_011740.1 490308 492968 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; acyl-CoA synthetase NAD(P)-binding subunit/ATP-binding subunit complement(490308..492968) Escherichia fergusonii ATCC 35469 7122307 YP_002381681.1 CDS yfiP NC_011740.1 493000 493698 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(493000..493698) Escherichia fergusonii ATCC 35469 7121479 YP_002381682.1 CDS trxC NC_011740.1 493767 494186 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12952960, 9388228, 99175138, 10644706; Product type c : carrier; thioredoxin 2 complement(493767..494186) Escherichia fergusonii ATCC 35469 7121478 YP_002381683.1 CDS EFER_0492 NC_011740.1 494200 494403 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 494200..494403 Escherichia fergusonii ATCC 35469 7122173 YP_002381684.1 CDS yfiF NC_011740.1 494393 495430 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; methyltransferase 494393..495430 Escherichia fergusonii ATCC 35469 7121589 YP_002381685.1 CDS ung NC_011740.1 495478 496167 R Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase complement(495478..496167) Escherichia fergusonii ATCC 35469 7121474 YP_002381686.1 CDS yfiD NC_011740.1 496472 496855 D stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit; autonomous glycyl radical cofactor GrcA 496472..496855 Escherichia fergusonii ATCC 35469 7122639 YP_002381687.1 CDS srmB NC_011740.1 497334 498668 R facilitates an early step in the assembly of the 50S subunit of the ribosome; ATP-dependent RNA helicase SrmB complement(497334..498668) Escherichia fergusonii ATCC 35469 7121473 YP_002381688.1 CDS yfiC NC_011740.1 498800 499537 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; S-adenosyl-L-methionine-dependent methyltransferase 498800..499537 Escherichia fergusonii ATCC 35469 7121940 YP_002381689.1 CDS nadB NC_011740.1 499522 501144 R catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase complement(499522..501144) Escherichia fergusonii ATCC 35469 7123872 YP_002381690.1 CDS rpoE NC_011740.1 501552 502127 D Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response; RNA polymerase sigma factor RpoE 501552..502127 Escherichia fergusonii ATCC 35469 7120658 YP_002381691.1 CDS rseA NC_011740.1 502160 502810 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9159522, 97303092, 99431977, 7768826; Product type f : factor; anti-RNA polymerase sigma factor SigE 502160..502810 Escherichia fergusonii ATCC 35469 7121122 YP_002381692.1 CDS rseB NC_011740.1 502810 503766 D periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP; periplasmic negative regulator of sigmaE 502810..503766 Escherichia fergusonii ATCC 35469 7121145 YP_002381693.1 CDS rseC NC_011740.1 503763 504242 D involved in the reduction of the SoxR iron-sulfur cluster; SoxR reducing system protein RseC 503763..504242 Escherichia fergusonii ATCC 35469 7121146 YP_002381694.1 CDS lepA NC_011740.1 504440 506239 D binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 504440..506239 Escherichia fergusonii ATCC 35469 7121147 YP_002381695.1 CDS lepB NC_011740.1 506255 507229 D catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins; signal peptidase I 506255..507229 Escherichia fergusonii ATCC 35469 7120822 YP_002381696.1 CDS rnc NC_011740.1 507502 508182 D cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 507502..508182 Escherichia fergusonii ATCC 35469 7120823 YP_002381697.1 CDS era NC_011740.1 508179 509084 D Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 508179..509084 Escherichia fergusonii ATCC 35469 7121423 YP_002381698.1 CDS recO NC_011740.1 509096 509824 D involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 509096..509824 Escherichia fergusonii ATCC 35469 7122960 YP_002381699.1 CDS pdxJ NC_011740.1 509836 510567 D involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 509836..510567 Escherichia fergusonii ATCC 35469 7121383 YP_002381700.1 CDS acpS NC_011740.1 510567 510947 D Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 510567..510947 Escherichia fergusonii ATCC 35469 7124064 YP_002381701.1 CDS EFER_0512 NC_011740.1 511206 511370 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 511206..511370 Escherichia fergusonii ATCC 35469 7123281 YP_002381702.1 CDS yfhL NC_011740.1 511640 511900 R Evidence 2b : Function of strongly homologous gene; PubMedId : 8765743, 8880900; Product type c : carrier; ferredoxin complement(511640..511900) Escherichia fergusonii ATCC 35469 7121590 YP_002381703.1 CDS yfhH NC_011740.1 511956 512804 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator complement(511956..512804) Escherichia fergusonii ATCC 35469 7121468 YP_002381704.1 CDS yfhB NC_011740.1 513013 513648 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 513013..513648 Escherichia fergusonii ATCC 35469 7121465 YP_002381705.1 CDS tadA NC_011740.1 513673 514209 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12110595; Product type e : enzyme; tRNA-specific adenosine deaminase 513673..514209 Escherichia fergusonii ATCC 35469 7123871 YP_002381706.1 CDS yfhD NC_011740.1 514206 515624 R YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function; transglycosylase complement(514206..515624) Escherichia fergusonii ATCC 35469 7121970 YP_002381707.1 CDS purL NC_011740.1 516020 519907 D catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 516020..519907 Escherichia fergusonii ATCC 35469 7121463 YP_002381708.1 CDS yfhK NC_011740.1 520482 521909 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; sensory kinase in two-component system 520482..521909 Escherichia fergusonii ATCC 35469 7122133 YP_002381709.1 CDS yfhG NC_011740.1 522074 522787 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 522074..522787 Escherichia fergusonii ATCC 35469 7121467 YP_002381710.1 CDS yfhA NC_011740.1 522777 524111 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8226691, 8412694; Product type pr : regulator; two component system DNA-binding response regulator 522777..524111 Escherichia fergusonii ATCC 35469 7121464 YP_002381711.1 CDS glnB NC_011740.1 524172 524510 D indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; nitrogen regulatory protein P-II 1 524172..524510 Escherichia fergusonii ATCC 35469 7121462 YP_002381712.1 CDS adk NC_011740.1 524761 525405 D essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 524761..525405 Escherichia fergusonii ATCC 35469 7120194 YP_002381713.1 CDS hemH NC_011740.1 525537 526499 D protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 525537..526499 Escherichia fergusonii ATCC 35469 7122277 YP_002381714.1 CDS aes NC_011740.1 526474 527490 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9401025, 98244813, 2051480, 7721718; Product type e : enzyme; acetyl esterase complement(526474..527490) Escherichia fergusonii ATCC 35469 7122184 YP_002381715.1 CDS gsk NC_011740.1 527594 528898 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90155203, 95238302, 2051480; Product type e : enzyme; inosine/guanosine kinase 527594..528898 Escherichia fergusonii ATCC 35469 7122280 YP_002381716.1 CDS EFER_0528 NC_011740.1 529054 529311 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 529054..529311 Escherichia fergusonii ATCC 35469 7120620 YP_002381717.1 CDS EFER_0529 NC_011740.1 529382 529843 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 529382..529843 Escherichia fergusonii ATCC 35469 7121591 YP_002381718.1 CDS ybaL NC_011740.1 529868 531544 R YbaL; member of the CPA-2 family of antiporters; uncharacterized protein; cation:proton antiport protein complement(529868..531544) Escherichia fergusonii ATCC 35469 7121592 YP_002381719.1 CDS fsr NC_011740.1 531778 532986 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21450803, 97074653, 8917080; Product type t : transporter; fosmidomycin efflux systemprotein complement(531778..532986) Escherichia fergusonii ATCC 35469 7121066 YP_002381720.1 CDS ushA NC_011740.1 533161 534813 D catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic 533161..534813 Escherichia fergusonii ATCC 35469 7123025 YP_002381721.1 CDS EFER_0533 NC_011740.1 534851 535354 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(534851..535354) Escherichia fergusonii ATCC 35469 7121172 YP_002381722.1 CDS EFER_0534 NC_011740.1 535351 536151 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(535351..536151) Escherichia fergusonii ATCC 35469 7121593 YP_002381723.1 CDS ybaK NC_011740.1 536175 536654 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(536175..536654) Escherichia fergusonii ATCC 35469 7121594 YP_002381724.1 CDS ybaP NC_011740.1 536858 537652 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(536858..537652) Escherichia fergusonii ATCC 35469 7121941 YP_002381725.1 CDS EFER_0537 NC_011740.1 537785 538087 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; RelE/ParE family protein, cytotoxic translational repressor of toxin-antitoxin stability system 537785..538087 Escherichia fergusonii ATCC 35469 7121069 YP_002381726.1 CDS ybaQ NC_011740.1 538123 538464 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator 538123..538464 Escherichia fergusonii ATCC 35469 7123895 YP_002381727.1 CDS copA NC_011740.1 538578 541082 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12351646, 20105527, 11167016, 11500054, 9868784; Product type t : transporter; copper exporting ATPase complement(538578..541082) Escherichia fergusonii ATCC 35469 7123262 YP_002381728.1 CDS ybaT NC_011740.1 541389 542678 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; nitrogen-containing metabolite transporter 541389..542678 Escherichia fergusonii ATCC 35469 7122793 YP_002381729.1 CDS siiCA NC_011740.1 543025 544380 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17220313, 15522082, 2905265; Product type t : transporter; outer membrane transport protein, type I secretion 543025..544380 Escherichia fergusonii ATCC 35469 7121071 YP_002381730.1 CDS siiEA NC_011740.1 544489 566157 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17220313, 15522082, 2905265; Product type f : factor; adhesin for cattle intestine colonization 544489..566157 Escherichia fergusonii ATCC 35469 7121784 YP_002381731.1 CDS siiBA NC_011740.1 566161 568323 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17220313, 15522082, 2905265, 2185213; Product type t : transporter; type I secretion membrane protein 566161..568323 Escherichia fergusonii ATCC 35469 7121786 YP_002381732.1 CDS siiDA NC_011740.1 568320 569495 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17220313, 15522082, 2905265; Product type t : transporter; RtxD/HlyD/CyaD protein of type I secretion system 568320..569495 Escherichia fergusonii ATCC 35469 7123922 YP_002381733.1 CDS cueR NC_011740.1 569492 569899 D activator of copper-responsive regulon genes; DNA-binding transcriptional regulator CueR 569492..569899 Escherichia fergusonii ATCC 35469 7121785 YP_002381734.1 CDS ybbJ NC_011740.1 569900 570358 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(569900..570358) Escherichia fergusonii ATCC 35469 7122827 YP_002381735.1 CDS ybbK NC_011740.1 570355 571272 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; protease, membrane anchored complement(570355..571272) Escherichia fergusonii ATCC 35469 7121077 YP_002381736.1 CDS ybbL NC_011740.1 571418 572095 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter ATP-binding protein 571418..572095 Escherichia fergusonii ATCC 35469 7121078 YP_002381737.1 CDS ybbM NC_011740.1 572082 572861 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; ABC transporter permease 572082..572861 Escherichia fergusonii ATCC 35469 7121079 YP_002381738.1 CDS ybbN NC_011740.1 573041 573895 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; thioredoxin domain-containing protein complement(573041..573895) Escherichia fergusonii ATCC 35469 7123264 YP_002381739.1 CDS ybbO NC_011740.1 573956 574765 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; short chain dehydrogenase complement(573956..574765) Escherichia fergusonii ATCC 35469 7121080 YP_002381740.1 CDS tesA NC_011740.1 574755 575381 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91270121, 91324311, 93163029, 93252782, 94179121, 99353977, 1864840, 8432696, 8098033; Product type e : enzyme; multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 complement(574755..575381) Escherichia fergusonii ATCC 35469 7121081 YP_002381741.1 CDS ybbA NC_011740.1 575349 576035 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter ATP-binding protein 575349..576035 Escherichia fergusonii ATCC 35469 7121985 YP_002381742.1 CDS ybbP NC_011740.1 576032 578446 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type t : transporter; ABC transporter permease 576032..578446 Escherichia fergusonii ATCC 35469 7121075 YP_002381743.1 CDS EFER_0555 NC_011740.1 578683 578898 D Evidence 6 : Doubtful CDS; hypothetical protein 578683..578898 Escherichia fergusonii ATCC 35469 7123265 YP_002381744.1 CDS EFER_0556 NC_011740.1 578996 579202 D Evidence 6 : Doubtful CDS; hypothetical protein 578996..579202 Escherichia fergusonii ATCC 35469 7121595 YP_002381745.1 CDS EFER_0557 NC_011740.1 579671 579829 D Evidence 6 : Doubtful CDS; hypothetical protein 579671..579829 Escherichia fergusonii ATCC 35469 7121596 YP_002381746.1 CDS EFER_0558 NC_011740.1 580256 580402 D Evidence 6 : Doubtful CDS; hypothetical protein 580256..580402 Escherichia fergusonii ATCC 35469 7123346 YP_002381747.1 CDS ybbB NC_011740.1 580595 581689 R catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA; tRNA 2-selenouridine synthase complement(580595..581689) Escherichia fergusonii ATCC 35469 7121597 YP_002381748.1 CDS ylbF NC_011740.1 581968 582621 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 581968..582621 Escherichia fergusonii ATCC 35469 7121076 YP_002381749.1 CDS ybcF NC_011740.1 582618 583511 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2464576, 2644189, 7920643, 7940673, 7984428; Product type pe : enzyme; carbamate kinase 582618..583511 Escherichia fergusonii ATCC 35469 7122043 YP_002381750.1 CDS purE NC_011740.1 584719 585228 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10074353, 8117684, 89123018, 89123019, 92287929, 10574791; Product type e : enzyme; N5-carboxyaminoimidazole ribonucleotide mutase complement(584719..585228) Escherichia fergusonii ATCC 35469 7122324 YP_002381751.1 CDS EFER_0565 NC_011740.1 585324 585653 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein complement(585324..585653) Escherichia fergusonii ATCC 35469 7122321 YP_002381752.1 CDS lpxH NC_011740.1 585764 586486 R catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase complement(585764..586486) Escherichia fergusonii ATCC 35469 7121598 YP_002381753.1 CDS ppiB NC_011740.1 586489 586983 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90272647, 91175755, 1606970, 1864365, 8601841, 9298646, 9600841; Product type e : enzyme; peptidyl-prolyl cis-trans isomerase B complement(586489..586983) Escherichia fergusonii ATCC 35469 7123282 YP_002381754.1 CDS cysS NC_011740.1 587157 588542 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 587157..588542 Escherichia fergusonii ATCC 35469 7123106 YP_002381755.1 CDS ybcI NC_011740.1 588578 589099 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(588578..589099) Escherichia fergusonii ATCC 35469 7122856 YP_002381756.1 CDS ybcJ NC_011740.1 589207 589419 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12837795, 1748668, 7567469; Product type pr : regulator; hypothetical protein complement(589207..589419) Escherichia fergusonii ATCC 35469 7121084 YP_002381757.1 CDS folD NC_011740.1 589421 590287 R catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase complement(589421..590287) Escherichia fergusonii ATCC 35469 7121085 YP_002381758.1 CDS intD NC_011740.1 590641 591804 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 90036709, 2183007; Product type pe : enzyme; integrase; DLP12 prophage complement(590641..591804) Escherichia fergusonii ATCC 35469 7120027 YP_002381759.1 CDS yfdT NC_011740.1 592031 592336 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(592031..592336) Escherichia fergusonii ATCC 35469 7120754 YP_002381760.1 CDS yfdS NC_011740.1 592336 592698 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(592336..592698) Escherichia fergusonii ATCC 35469 7119838 YP_002381761.1 CDS yfdR NC_011740.1 592689 593225 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(592689..593225) Escherichia fergusonii ATCC 35469 7119837 YP_002381762.1 CDS yfdQ NC_011740.1 593353 594177 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(593353..594177) Escherichia fergusonii ATCC 35469 7119835 YP_002381763.1 CDS EFER_0577 NC_011740.1 594243 594923 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(594243..594923) Escherichia fergusonii ATCC 35469 7123058 YP_002381764.1 CDS EFER_0578 NC_011740.1 594417 594902 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 594417..594902 Escherichia fergusonii ATCC 35469 7123347 YP_002381765.1 CDS EFER_0579 NC_011740.1 595074 595508 D Evidence 6 : Doubtful CDS; Product type h : extrachromosomal origin; hypothetical protein 595074..595508 Escherichia fergusonii ATCC 35469 7121599 YP_002381766.1 CDS EFER_0580 NC_011740.1 595480 595701 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(595480..595701) Escherichia fergusonii ATCC 35469 7121600 YP_002381767.1 CDS EFER_0581 NC_011740.1 595922 596842 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 595922..596842 Escherichia fergusonii ATCC 35469 7121601 YP_002381768.1 CDS EFER_0582 NC_011740.1 596825 597511 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; Cro/CI family transcriptional regulator complement(596825..597511) Escherichia fergusonii ATCC 35469 7121602 YP_002381769.1 CDS EFER_0583 NC_011740.1 597647 597895 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 597647..597895 Escherichia fergusonii ATCC 35469 7121603 YP_002381770.1 CDS ymfL NC_011740.1 597813 598469 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; nucleic acid-binding protein; e14 prophage 597813..598469 Escherichia fergusonii ATCC 35469 7121604 YP_002381771.1 CDS ymfM NC_011740.1 598466 598804 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 598466..598804 Escherichia fergusonii ATCC 35469 7122056 YP_002381772.1 CDS EFER_0587 NC_011740.1 598814 599755 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; phage replication protein O 598814..599755 Escherichia fergusonii ATCC 35469 7122058 YP_002381773.1 CDS yfdN NC_011740.1 599752 600246 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 599752..600246 Escherichia fergusonii ATCC 35469 7123896 YP_002381774.1 CDS EFER_0589 NC_011740.1 600213 600899 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; phage AdoMet-dependent methyltransferase 600213..600899 Escherichia fergusonii ATCC 35469 7119832 YP_002381775.1 CDS EFER_0590 NC_011740.1 600896 601222 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; LexA repressor 600896..601222 Escherichia fergusonii ATCC 35469 7121605 YP_002381776.1 CDS rusA NC_011740.1 601219 601608 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Crossover junction endodeoxyribonuclease 601219..601608 Escherichia fergusonii ATCC 35469 7121606 YP_002381777.1 CDS EFER_0592 NC_011740.1 601628 602425 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 601628..602425 Escherichia fergusonii ATCC 35469 7121165 YP_002381778.1 CDS EFER_0593 NC_011740.1 602427 603422 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 602427..603422 Escherichia fergusonii ATCC 35469 7121607 YP_002381779.1 CDS EFER_0594 NC_011740.1 603425 603802 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; antitermination protein Q from phage origin 603425..603802 Escherichia fergusonii ATCC 35469 7121608 YP_002381780.1 CDS EFER_0595 NC_011740.1 603853 604599 R Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein complement(603853..604599) Escherichia fergusonii ATCC 35469 7121609 YP_002381781.1 CDS S NC_011740.1 604866 605192 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2998005; Product type h : extrachromosomal origin; Holin 604866..605192 Escherichia fergusonii ATCC 35469 7121610 YP_002381782.1 CDS r NC_011740.1 605196 605672 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; lysozyme 605196..605672 Escherichia fergusonii ATCC 35469 7123824 YP_002381783.1 CDS EFER_0598 NC_011740.1 605656 606048 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; Rz lytic protein from phage origin, coiled-coil 605656..606048 Escherichia fergusonii ATCC 35469 7122343 YP_002381784.1 CDS EFER_0599 NC_011740.1 606562 607008 D Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 606562..607008 Escherichia fergusonii ATCC 35469 7121611 YP_002381785.1 CDS EFER_0600 NC_011740.1 607136 607486 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; endonuclease 607136..607486 Escherichia fergusonii ATCC 35469 7121612 YP_002381786.1 CDS EFER_0601 NC_011740.1 607603 608106 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; phage terminase small subunit 607603..608106 Escherichia fergusonii ATCC 35469 7121613 YP_002381787.1 CDS EFER_0602 NC_011740.1 608103 609836 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; phage terminase 608103..609836 Escherichia fergusonii ATCC 35469 7123897 YP_002381788.1 CDS ymfR NC_011740.1 609848 610030 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 609848..610030 Escherichia fergusonii ATCC 35469 7121614 YP_002381789.1 CDS EFER_0604 NC_011740.1 610030 611271 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; phage portal protein 610030..611271 Escherichia fergusonii ATCC 35469 7121688 YP_002381790.1 CDS EFER_0605 NC_011740.1 611213 611899 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; phage pro-head protease 611213..611899 Escherichia fergusonii ATCC 35469 7123348 YP_002381791.1 CDS EFER_0606 NC_011740.1 611914 613119 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; major capsid protein 611914..613119 Escherichia fergusonii ATCC 35469 7121615 YP_002381792.1 CDS EFER_0607 NC_011740.1 613169 613369 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 613169..613369 Escherichia fergusonii ATCC 35469 7121616 YP_002381793.1 CDS EFER_0608 NC_011740.1 613372 613695 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 613372..613695 Escherichia fergusonii ATCC 35469 7123349 YP_002381794.1 CDS EFER_0609 NC_011740.1 613692 614102 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; phage head-tail adaptor 613692..614102 Escherichia fergusonii ATCC 35469 7121617 YP_002381795.1 CDS EFER_0610 NC_011740.1 614077 614583 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 614077..614583 Escherichia fergusonii ATCC 35469 7121618 YP_002381796.1 CDS EFER_0611 NC_011740.1 614580 615140 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 614580..615140 Escherichia fergusonii ATCC 35469 7123350 YP_002381797.1 CDS EFER_0612 NC_011740.1 615149 615319 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 615149..615319 Escherichia fergusonii ATCC 35469 7121619 YP_002381798.1 CDS EFER_0613 NC_011740.1 615303 616799 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; tail sheath protein 615303..616799 Escherichia fergusonii ATCC 35469 7121620 YP_002381799.1 CDS EFER_0614 NC_011740.1 616799 617155 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; phage tail protein 616799..617155 Escherichia fergusonii ATCC 35469 7121621 YP_002381800.1 CDS EFER_0615 NC_011740.1 617155 617424 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 617155..617424 Escherichia fergusonii ATCC 35469 7123898 YP_002381801.1 CDS EFER_0616 NC_011740.1 617566 619398 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; phage tail tape measure protein 617566..619398 Escherichia fergusonii ATCC 35469 7121622 YP_002381802.1 CDS EFER_0617 NC_011740.1 619480 619992 D Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 619480..619992 Escherichia fergusonii ATCC 35469 7121623 YP_002381803.1 CDS EFER_0618 NC_011740.1 620083 621411 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; tail/DNA circulation protein 620083..621411 Escherichia fergusonii ATCC 35469 7123899 YP_002381804.1 CDS EFER_0619 NC_011740.1 621408 622487 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; tail protein 621408..622487 Escherichia fergusonii ATCC 35469 7121624 YP_002381805.1 CDS EFER_0620 NC_011740.1 622487 623035 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; baseplate assembly phage protein 622487..623035 Escherichia fergusonii ATCC 35469 7123351 YP_002381806.1 CDS EFER_0621 NC_011740.1 623032 623460 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; tail protein 623032..623460 Escherichia fergusonii ATCC 35469 7121625 YP_002381807.1 CDS EFER_0622 NC_011740.1 623447 624505 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; baseplate J-like phage protein 623447..624505 Escherichia fergusonii ATCC 35469 7120144 YP_002381808.1 CDS ymfQ NC_011740.1 624496 625080 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 624496..625080 Escherichia fergusonii ATCC 35469 7120206 YP_002381809.1 CDS EFER_0624 NC_011740.1 625084 626013 D Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 625084..626013 Escherichia fergusonii ATCC 35469 7123928 YP_002381810.1 CDS EFER_0625 NC_011740.1 625989 626549 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 625989..626549 Escherichia fergusonii ATCC 35469 7120207 YP_002381811.1 CDS EFER_0626 NC_011740.1 626947 628074 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein complement(626947..628074) Escherichia fergusonii ATCC 35469 7120208 YP_002381812.1 CDS EFER_0627 NC_011740.1 629487 629636 D Evidence 6 : Doubtful CDS; hypothetical protein 629487..629636 Escherichia fergusonii ATCC 35469 7120209 YP_002381813.1 CDS yfdH NC_011740.1 629928 630860 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12878731, 13129938, 9689094; Product type h : extrachromosomal origin; bactoprenol glucosyl transferase; CPS-53 (KpLE1) prophage complement(629928..630860) Escherichia fergusonii ATCC 35469 7120210 YP_002381814.1 CDS yfdG NC_011740.1 630857 631219 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12878731, 13129938, 9689094; Product type h : extrachromosomal origin; bactoprenol-linked glucose translocase (flippase) ; CPS-53 (KpLE1) prophage complement(630857..631219) Escherichia fergusonii ATCC 35469 7119831 YP_002381815.1 CDS hmp NC_011740.1 631591 632781 R flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; nitric oxide dioxygenase complement(631591..632781) Escherichia fergusonii ATCC 35469 7119830 YP_002381816.1 CDS glyA NC_011740.1 633109 634362 D catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 633109..634362 Escherichia fergusonii ATCC 35469 7123999 YP_002381817.1 CDS yphA NC_011740.1 634411 634905 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(634411..634905) Escherichia fergusonii ATCC 35469 7120589 YP_002381818.1 CDS hcaT NC_011740.1 635062 636201 D transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters; 3-phenylpropionic acid transporter 635062..636201 Escherichia fergusonii ATCC 35469 7119717 YP_002381819.1 CDS csiE NC_011740.1 636193 637473 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type ph : phenotype; stationary phase inducible protein CsiE complement(636193..637473) Escherichia fergusonii ATCC 35469 7123192 YP_002381820.1 CDS yfhR NC_011740.1 637669 638520 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; peptidase complement(637669..638520) Escherichia fergusonii ATCC 35469 7122815 YP_002381821.1 CDS suhB NC_011740.1 638654 639457 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6389495, 90202735, 95095968, 10747806, 2138605, 8002619; Product type e : enzyme; inositol monophosphatase complement(638654..639457) Escherichia fergusonii ATCC 35469 7121471 YP_002381822.1 CDS yfhQ NC_011740.1 639576 640316 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10393315; Product type pe : enzyme; methyltransferase 639576..640316 Escherichia fergusonii ATCC 35469 7121965 YP_002381823.1 CDS iscR NC_011740.1 640586 641074 D regulates the expression of the iscRSUA operon; DNA-binding transcriptional regulator IscR 640586..641074 Escherichia fergusonii ATCC 35469 7121470 YP_002381824.1 CDS iscS NC_011740.1 641315 642529 D catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 641315..642529 Escherichia fergusonii ATCC 35469 7120756 YP_002381825.1 CDS iscU NC_011740.1 642557 642943 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10393315, 11994302, 15153099; Product type f : factor; scaffold protein 642557..642943 Escherichia fergusonii ATCC 35469 7120757 YP_002381826.1 CDS iscA NC_011740.1 642960 643283 D forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein; iron-sulfur cluster assembly protein 642960..643283 Escherichia fergusonii ATCC 35469 7120758 YP_002381827.1 CDS hscB NC_011740.1 643379 643894 D J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins; co-chaperone HscB 643379..643894 Escherichia fergusonii ATCC 35469 7123216 YP_002381828.1 CDS hscA NC_011740.1 643911 645761 D involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA 643911..645761 Escherichia fergusonii ATCC 35469 7123445 YP_002381829.1 CDS fdx NC_011740.1 645763 646098 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10393315, 20013001, 92283811, 94181532, 11551196, 1317854, 4375562, 8300516; Product type c : carrier; [2Fe-2S] ferredoxin 645763..646098 Escherichia fergusonii ATCC 35469 7122222 YP_002381830.1 CDS yfhJ NC_011740.1 646110 646310 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10393315; Product type pf : factor; hypothetical protein 646110..646310 Escherichia fergusonii ATCC 35469 7120002 YP_002381831.1 CDS pepB NC_011740.1 646488 647771 D catalyzes the removal of an N-terminal amino acid from a peptide or arylamide; aminopeptidase B 646488..647771 Escherichia fergusonii ATCC 35469 7121466 YP_002381832.1 CDS sseB NC_011740.1 647890 648666 D enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I; enhanced serine sensitivity protein SseB 647890..648666 Escherichia fergusonii ATCC 35469 7122575 YP_002381833.1 CDS sseA NC_011740.1 649431 650276 R catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds; 3-mercaptopyruvate sulfurtransferase complement(649431..650276) Escherichia fergusonii ATCC 35469 7120755 YP_002381834.1 CDS yfhM NC_011740.1 650482 655461 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 650482..655461 Escherichia fergusonii ATCC 35469 7123399 YP_002381835.1 CDS pbpC NC_011740.1 655462 657774 D penicillin-insensitive transglycosylase/transpeptidase; penicillin-binding protein 1C 655462..657774 Escherichia fergusonii ATCC 35469 7121469 YP_002381836.1 CDS ndk NC_011740.1 657922 658353 D catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 657922..658353 Escherichia fergusonii ATCC 35469 7122558 YP_002381837.1 CDS yfgB NC_011740.1 658503 659657 D 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 658503..659657 Escherichia fergusonii ATCC 35469 7120683 YP_002381838.1 CDS yfgA NC_011740.1 659948 660964 D Evidence 4 : Homologs of previously reported genes of unknown function; cytoskeletal protein RodZ 659948..660964 Escherichia fergusonii ATCC 35469 7121457 YP_002381839.1 CDS ispG NC_011740.1 660991 662109 D catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 660991..662109 Escherichia fergusonii ATCC 35469 7121456 YP_002381840.1 CDS hisS NC_011740.1 662220 663509 D catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 662220..663509 Escherichia fergusonii ATCC 35469 7120794 YP_002381841.1 CDS yfgM NC_011740.1 663527 664147 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 663527..664147 Escherichia fergusonii ATCC 35469 7122203 YP_002381842.1 CDS yfgL NC_011740.1 664158 665336 D with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis; outer membrane protein assembly complex subunit YfgL 664158..665336 Escherichia fergusonii ATCC 35469 7121461 YP_002381843.1 CDS engA NC_011740.1 665455 666927 D EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 665455..666927 Escherichia fergusonii ATCC 35469 7121460 YP_002381844.1 CDS EFER_0662 NC_011740.1 666990 667205 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 666990..667205 Escherichia fergusonii ATCC 35469 7122891 YP_002381845.1 CDS EFER_0663 NC_011740.1 667397 669589 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8500884, 3304658, 12540539; Product type pf : factor; intimin 667397..669589 Escherichia fergusonii ATCC 35469 7123121 YP_002381846.1 CDS EFER_0664 NC_011740.1 669639 670637 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 669639..670637 Escherichia fergusonii ATCC 35469 7120211 YP_002381847.1 CDS EFER_0665 NC_011740.1 670747 678834 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 670747..678834 Escherichia fergusonii ATCC 35469 7123662 YP_002381848.1 CDS xseA NC_011740.1 678889 680256 R bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit complement(678889..680256) Escherichia fergusonii ATCC 35469 7120212 YP_002381849.1 CDS guaB NC_011740.1 680418 681884 D catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 680418..681884 Escherichia fergusonii ATCC 35469 7122385 YP_002381850.1 CDS guaA NC_011740.1 681953 683530 D contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 681953..683530 Escherichia fergusonii ATCC 35469 7123190 YP_002381851.1 CDS EFER_0669 NC_011740.1 683618 684244 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(683618..684244) Escherichia fergusonii ATCC 35469 7120623 YP_002381852.1 CDS yfgI NC_011740.1 684350 684898 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(684350..684898) Escherichia fergusonii ATCC 35469 7120213 YP_002381853.1 CDS yfgH NC_011740.1 684914 685477 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; outer membrane lipoprotein complement(684914..685477) Escherichia fergusonii ATCC 35469 7121459 YP_002381854.1 CDS EFER_0672 NC_011740.1 685619 685912 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 685619..685912 Escherichia fergusonii ATCC 35469 7123324 YP_002381855.1 CDS EFER_0673 NC_011740.1 686282 688531 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 686282..688531 Escherichia fergusonii ATCC 35469 7120214 YP_002381856.1 CDS ppx NC_011740.1 688602 690221 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93107072, 94025037, 94165003, 8212131, 8380170; Product type e : enzyme; exopolyphosphatase complement(688602..690221) Escherichia fergusonii ATCC 35469 7120215 YP_002381857.1 CDS ppk NC_011740.1 690139 692205 R catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase complement(690139..692205) Escherichia fergusonii ATCC 35469 7120118 YP_002381858.1 CDS purN NC_011740.1 692406 693047 R glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase complement(692406..693047) Escherichia fergusonii ATCC 35469 7123646 YP_002381859.1 CDS purM NC_011740.1 693044 694081 R catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase complement(693044..694081) Escherichia fergusonii ATCC 35469 7122326 YP_002381860.1 CDS upp NC_011740.1 694315 694941 D Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 694315..694941 Escherichia fergusonii ATCC 35469 7122325 YP_002381861.1 CDS uraA NC_011740.1 695027 696316 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8332529, 7721693; Product type t : transporter; uracil transporter 695027..696316 Escherichia fergusonii ATCC 35469 7122640 YP_002381862.1 CDS hda NC_011740.1 696388 697113 D controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP; DNA replication initiation factor 696388..697113 Escherichia fergusonii ATCC 35469 7122641 YP_002381863.1 CDS yfgD NC_011740.1 697147 697506 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; oxidoreductase complement(697147..697506) Escherichia fergusonii ATCC 35469 7120632 YP_002381864.1 CDS yfgC NC_011740.1 697527 698990 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; peptidase complement(697527..698990) Escherichia fergusonii ATCC 35469 7123323 YP_002381865.1 CDS perM NC_011740.1 699204 700265 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; permease 699204..700265 Escherichia fergusonii ATCC 35469 7121458 YP_002381866.1 CDS EFER_0684 NC_011740.1 700303 702315 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type r : regulator; hydrogenase-4 transcriptional activator complement(700303..702315) Escherichia fergusonii ATCC 35469 7122580 YP_002381867.1 CDS EFER_0685 NC_011740.1 702312 702740 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; processing element hydrogenase 4 complement(702312..702740) Escherichia fergusonii ATCC 35469 7123663 YP_002381868.1 CDS hyfI NC_011740.1 702733 703539 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9387241; Product type c : carrier; hydrogenase 4, Fe-S subunit complement(702733..703539) Escherichia fergusonii ATCC 35469 7123664 YP_002381869.1 CDS EFER_0687 NC_011740.1 703497 704045 R probable electron transfer protein for hydrogenase 4; hydrogenase 4 is believed to be silent in E. coli under conditions tested so far; hydrogenase 4 subunit H complement(703497..704045) Escherichia fergusonii ATCC 35469 7123739 YP_002381870.1 CDS hyfG NC_011740.1 704055 705770 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9387241; Product type c : carrier; hydrogenase 4 subunit complement(704055..705770) Escherichia fergusonii ATCC 35469 7120216 YP_002381871.1 CDS hyfF NC_011740.1 705760 707340 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9387241; Product type m : membrane component; hydrogenase 4 subunit F complement(705760..707340) Escherichia fergusonii ATCC 35469 7120711 YP_002381872.1 CDS hyfE NC_011740.1 707345 707995 R interacts with formate dehydrogenase to produce an active formate hydrogenlyase complex which cleaves formate to dihydrogen and carbon dioxide; hydrogenase 4 membrane subunit complement(707345..707995) Escherichia fergusonii ATCC 35469 7120710 YP_002381873.1 CDS hyfD NC_011740.1 708007 709455 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9387241; Product type m : membrane component; hydrogenase 4 subunit D complement(708007..709455) Escherichia fergusonii ATCC 35469 7123738 YP_002381874.1 CDS hyfC NC_011740.1 709462 710409 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9387241; Product type m : membrane component; hydrogenase 4, membrane subunit complement(709462..710409) Escherichia fergusonii ATCC 35469 7123208 YP_002381875.1 CDS EFER_0693 NC_011740.1 710420 712495 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hydrogenase 4 subunit B complement(710420..712495) Escherichia fergusonii ATCC 35469 7120709 YP_002381876.1 CDS EFER_0694 NC_011740.1 712441 713058 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; hydrogenase 4, 4Fe-4S subunit complement(712441..713058) Escherichia fergusonii ATCC 35469 7120217 YP_002381877.1 CDS bcp NC_011740.1 713304 713774 R bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine; thioredoxin-dependent thiol peroxidase complement(713304..713774) Escherichia fergusonii ATCC 35469 7120218 YP_002381878.1 CDS gcvR NC_011740.1 713774 714346 R negative transcriptional regulator of the gcvTHP operon; glycine cleavage system transcriptional repressor complement(713774..714346) Escherichia fergusonii ATCC 35469 7121647 YP_002381879.1 CDS dapA NC_011740.1 714493 715371 D catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 714493..715371 Escherichia fergusonii ATCC 35469 7120181 YP_002381880.1 CDS nlpB NC_011740.1 715388 716422 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91358331, 1885529, 2120198; Product type lp : lipoprotein; lipoprotein 715388..716422 Escherichia fergusonii ATCC 35469 7122866 YP_002381881.1 CDS purC NC_011740.1 716634 717347 D catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazolesuccinocarboxamide synthase 716634..717347 Escherichia fergusonii ATCC 35469 7120697 YP_002381882.1 CDS ypfJ NC_011740.1 717515 718378 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 717515..718378 Escherichia fergusonii ATCC 35469 7122319 YP_002381883.1 CDS ypfI NC_011740.1 718393 720408 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hydrolase 718393..720408 Escherichia fergusonii ATCC 35469 7121748 YP_002381884.1 CDS ypfH NC_011740.1 720482 721180 D Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YpfH 720482..721180 Escherichia fergusonii ATCC 35469 7123369 YP_002381885.1 CDS ypfN NC_011740.1 721273 721473 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(721273..721473) Escherichia fergusonii ATCC 35469 7121747 YP_002381886.1 CDS dapE NC_011740.1 721501 722628 R dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase complement(721501..722628) Escherichia fergusonii ATCC 35469 7121749 YP_002381887.1 CDS yffB NC_011740.1 722632 722988 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(722632..722988) Escherichia fergusonii ATCC 35469 7122867 YP_002381888.1 CDS acrD NC_011740.1 723538 726651 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12426336, 20158894, 21450803, 79216220, 10692383, 1644752; Product type t : transporter; aminoglycoside/multidrug efflux system complement(723538..726651) Escherichia fergusonii ATCC 35469 7121453 YP_002381889.1 CDS narQ NC_011740.1 726770 728482 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92374842, 1508040, 1528845; Product type r : regulator; nitrate/nitrite sensor protein NarQ complement(726770..728482) Escherichia fergusonii ATCC 35469 7122267 YP_002381890.1 CDS aegA NC_011740.1 728567 730675 D unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic); oxidoreductase Fe-S binding subunit 728567..730675 Escherichia fergusonii ATCC 35469 7120680 YP_002381891.1 CDS yffH NC_011740.1 730743 731318 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; NUDIX hydrolase 730743..731318 Escherichia fergusonii ATCC 35469 7123456 YP_002381892.1 CDS ypfG NC_011740.1 731417 732484 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 731417..732484 Escherichia fergusonii ATCC 35469 7121454 YP_002381893.1 CDS tktB NC_011740.1 732503 734506 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(732503..734506) Escherichia fergusonii ATCC 35469 7121746 YP_002381894.1 CDS talA NC_011740.1 734529 735479 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90230300; Product type e : enzyme; transaldolase A complement(734529..735479) Escherichia fergusonii ATCC 35469 7122135 YP_002381895.1 CDS maeB NC_011740.1 735754 738033 D NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 735754..738033 Escherichia fergusonii ATCC 35469 7121972 YP_002381896.1 CDS ypfE NC_011740.1 738328 738663 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type ps : structure; carboxysome-like ethanolaminosome structural protein 738328..738663 Escherichia fergusonii ATCC 35469 7121221 YP_002381897.1 CDS eutP NC_011740.1 738676 739155 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type pe : enzyme; nucleoside triphosphate hydrolase domain-containing protein 738676..739155 Escherichia fergusonii ATCC 35469 7121745 YP_002381898.1 CDS eutQ NC_011740.1 739130 739831 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10464203; hypothetical protein 739130..739831 Escherichia fergusonii ATCC 35469 7119972 YP_002381899.1 CDS eutT NC_011740.1 739828 740631 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type pe : enzyme; cobalamin adenosyltransferase 739828..740631 Escherichia fergusonii ATCC 35469 7119973 YP_002381900.1 CDS eutD NC_011740.1 740628 741644 D in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase 740628..741644 Escherichia fergusonii ATCC 35469 7123623 YP_002381901.1 CDS cchA NC_011740.1 741683 741976 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type ps : structure; carboxysome-like ethanolaminosome structural protein 741683..741976 Escherichia fergusonii ATCC 35469 7123622 YP_002381902.1 CDS cchB NC_011740.1 742083 742370 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type ps : structure; carboxysome-like ethanolaminosome structural protein 742083..742370 Escherichia fergusonii ATCC 35469 7120865 YP_002381903.1 CDS eutE NC_011740.1 742382 743785 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type pe : enzyme; aldehyde dehydrogenase 742382..743785 Escherichia fergusonii ATCC 35469 7120866 YP_002381904.1 CDS eutJ NC_011740.1 743796 744632 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type pf : factor; chaperonin 743796..744632 Escherichia fergusonii ATCC 35469 7119968 YP_002381905.1 CDS eutG NC_011740.1 744622 745809 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type pe : enzyme; alcohol dehydrogenase 744622..745809 Escherichia fergusonii ATCC 35469 7119970 YP_002381906.1 CDS eutH NC_011740.1 745926 747152 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7868611, 10464203; Product type pt : transporter; ethanolamine transporter 745926..747152 Escherichia fergusonii ATCC 35469 7119969 YP_002381907.1 CDS eutA NC_011740.1 747149 748552 D ethanolamine utilization protein EutA; reactivating factor for ethanolamine ammonia lyase 747149..748552 Escherichia fergusonii ATCC 35469 7123621 YP_002381908.1 CDS eutB NC_011740.1 748564 749925 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3905806, 10464203; Product type e : enzyme; ethanolamine ammonia-lyase large subunit 748564..749925 Escherichia fergusonii ATCC 35469 7119966 YP_002381909.1 CDS eutC NC_011740.1 749946 750833 D catalyzes the formation of acetaldehyde from ethanolamine; ethanolamine ammonia-lyase small subunit 749946..750833 Escherichia fergusonii ATCC 35469 7119967 YP_002381910.1 CDS eutL NC_011740.1 750843 751502 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16291677, 10464203; Product type ps : structure; carboxysome-like ethanolaminosome structural protein 750843..751502 Escherichia fergusonii ATCC 35469 7123620 YP_002381911.1 CDS yffI NC_011740.1 751515 752015 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10464203; Product type ps : structure; ethanolaminosome structural protein 751515..752015 Escherichia fergusonii ATCC 35469 7119971 YP_002381912.1 CDS yfeG NC_011740.1 752061 753113 D activates the transcription of the ethanolamine utilization operon; transcriptional regulator EutR 752061..753113 Escherichia fergusonii ATCC 35469 7121455 YP_002381913.1 CDS EFER_0734 NC_011740.1 753190 753582 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(753190..753582) Escherichia fergusonii ATCC 35469 7121446 YP_002381914.1 CDS EFER_0735 NC_011740.1 753546 754808 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(753546..754808) Escherichia fergusonii ATCC 35469 7123122 YP_002381915.1 CDS hemF NC_011740.1 754946 755845 R catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase complement(754946..755845) Escherichia fergusonii ATCC 35469 7120219 YP_002381916.1 CDS amiA NC_011740.1 755849 756718 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21348478, 6137479, 87242501, 1903834, 8300522; Product type e : enzyme; N-acetylmuramoyl-l-alanine amidase I complement(755849..756718) Escherichia fergusonii ATCC 35469 7122182 YP_002381917.1 CDS ypeA NC_011740.1 756931 757356 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; acetyltransferase 756931..757356 Escherichia fergusonii ATCC 35469 7124015 YP_002381918.1 CDS yfeZ NC_011740.1 757343 757792 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 757343..757792 Escherichia fergusonii ATCC 35469 7121744 YP_002381919.1 CDS yfeY NC_011740.1 757853 758428 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12900013, 7764507; hypothetical protein 757853..758428 Escherichia fergusonii ATCC 35469 7121452 YP_002381920.1 CDS yfeX NC_011740.1 758524 759423 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 758524..759423 Escherichia fergusonii ATCC 35469 7121451 YP_002381921.1 CDS murQ NC_011740.1 759520 760785 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15983044, 15060041; Product type e : enzyme; hypothetical protein complement(759520..760785) Escherichia fergusonii ATCC 35469 7123870 YP_002381922.1 CDS murP NC_011740.1 760788 762212 R belongs to PEP-dependent PTS system; contains the PTS EIIBC domains; involved in uptake of exogenous N-acetylmuramic acid (MurNAc); requires crr-encoded enzyme IIA-glucose component; PTS system N-acetylmuramic acid transporter subunit IIBC complement(760788..762212) Escherichia fergusonii ATCC 35469 7120651 YP_002381923.1 CDS murQ NC_011740.1 762216 763112 R catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase complement(762216..763112) Escherichia fergusonii ATCC 35469 7120650 YP_002381924.1 CDS yfeT NC_011740.1 763276 764133 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator 763276..764133 Escherichia fergusonii ATCC 35469 7123869 YP_002381925.1 CDS ucpA NC_011740.1 764262 765053 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 97385354, 2188959, 7984428, 9241368; Product type pe : enzyme; short chain dehydrogenase 764262..765053 Escherichia fergusonii ATCC 35469 7121450 YP_002381926.1 CDS cysP NC_011740.1 765357 766373 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90264335, 2188959, 9298646; Product type t : transporter; thiosulfate transporter subunit 765357..766373 Escherichia fergusonii ATCC 35469 7124074 YP_002381927.1 CDS cysU NC_011740.1 766373 767206 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90264334, 2188958; Product type t : transporter; sulfate/thiosulfate transporter subunit 766373..767206 Escherichia fergusonii ATCC 35469 7122854 YP_002381928.1 CDS cysW NC_011740.1 767206 768081 D Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import; sulfate/thiosulfate transporter permease subunit 767206..768081 Escherichia fergusonii ATCC 35469 7122857 YP_002381929.1 CDS cysA NC_011740.1 768071 769168 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90202710, 90264334, 2188958, 7665461; Product type t : transporter; sulfate/thiosulfate transporter subunit 768071..769168 Escherichia fergusonii ATCC 35469 7122858 YP_002381930.1 CDS cysM NC_011740.1 769303 770214 D catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; cysteine synthase B 769303..770214 Escherichia fergusonii ATCC 35469 7122845 YP_002381931.1 CDS yfeK NC_011740.1 770217 770585 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(770217..770585) Escherichia fergusonii ATCC 35469 7123544 YP_002381932.1 CDS pdxK NC_011740.1 770690 771541 D catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxal kinase 770690..771541 Escherichia fergusonii ATCC 35469 7121448 YP_002381933.1 CDS crr NC_011740.1 771585 772094 R functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter complement(771585..772094) Escherichia fergusonii ATCC 35469 7122573 YP_002381934.1 CDS ptsI NC_011740.1 772135 773862 R Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase complement(772135..773862) Escherichia fergusonii ATCC 35469 7122809 YP_002381935.1 CDS ptsH NC_011740.1 773909 774166 R Evidence 1b : Function experimentally demonstrated in the studied species; Product type t : transporter; PTS system phosphohistidinoprotein-hexose phosphotransferase Hpr complement(773909..774166) Escherichia fergusonii ATCC 35469 7123462 YP_002381936.1 CDS cysK NC_011740.1 774548 775519 R CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A complement(774548..775519) Escherichia fergusonii ATCC 35469 7122315 YP_002381937.1 CDS cysZ NC_011740.1 775683 776444 R role in sulfur assimilation; sulfate transport protein CysZ complement(775683..776444) Escherichia fergusonii ATCC 35469 7122853 YP_002381938.1 CDS zipA NC_011740.1 776624 777679 D interacts with cell division protein FitsZ and may be required to anchor septal ring structure; cell division protein ZipA 776624..777679 Escherichia fergusonii ATCC 35469 7124114 YP_002381939.1 CDS ligA NC_011740.1 777750 779765 D this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 777750..779765 Escherichia fergusonii ATCC 35469 7119772 YP_002381940.1 CDS EFER_0764 NC_011740.1 779674 779985 D Evidence 6 : Doubtful CDS; hypothetical protein 779674..779985 Escherichia fergusonii ATCC 35469 7120832 YP_002381941.1 CDS yfeH NC_011740.1 779982 780980 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; sodium/bile acid symporter familyprotein complement(779982..780980) Escherichia fergusonii ATCC 35469 7120220 YP_002381942.1 CDS yfeN NC_011740.1 781257 782036 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein complement(781257..782036) Escherichia fergusonii ATCC 35469 7121447 YP_002381943.1 CDS xapA NC_011740.1 782292 783125 D catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 782292..783125 Escherichia fergusonii ATCC 35469 7121449 YP_002381944.1 CDS xapB NC_011740.1 783183 784439 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96032385, 7559336; Product type t : transporter; xanthosine transporter 783183..784439 Escherichia fergusonii ATCC 35469 7122381 YP_002381945.1 CDS xapR NC_011740.1 784809 785693 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7559336; Product type r : regulator; DNA-binding transcriptional activator XapR 784809..785693 Escherichia fergusonii ATCC 35469 7122382 YP_002381946.1 CDS gltX NC_011740.1 786402 787817 D Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 786402..787817 Escherichia fergusonii ATCC 35469 7120084 YP_002381947.1 CDS yfeD NC_011740.1 787865 788257 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; nucleic acid-binding transcriptional regulator complement(787865..788257) Escherichia fergusonii ATCC 35469 7120588 YP_002381948.1 CDS yfeC NC_011740.1 788259 788618 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; nucleic acid-binding transcriptional regulator complement(788259..788618) Escherichia fergusonii ATCC 35469 7123321 YP_002381949.1 CDS EFER_0775 NC_011740.1 789165 791423 D hypothetical protein 789165..791423 Escherichia fergusonii ATCC 35469 7123091 YP_002381950.1 CDS nupC NC_011740.1 791516 792718 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 374403, 8022285, 7007808, 827549, 4563236, 1512211; Product type t : transporter; nucleoside (except guanosine) transporter complement(791516..792718) Escherichia fergusonii ATCC 35469 7120221 YP_002381951.1 CDS mntH NC_011740.1 793054 794292 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20177822, 20305051, 10712688, 10844693; Product type t : transporter; manganese transport protein MntH 793054..794292 Escherichia fergusonii ATCC 35469 7123576 YP_002381952.1 CDS ypeC NC_011740.1 794360 794686 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(794360..794686) Escherichia fergusonii ATCC 35469 7120944 YP_002381953.1 CDS yfeO NC_011740.1 794801 796057 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; hypothetical protein complement(794801..796057) Escherichia fergusonii ATCC 35469 7123918 YP_002381954.1 CDS glk NC_011740.1 796261 797226 D catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase 796261..797226 Escherichia fergusonii ATCC 35469 7123322 YP_002381955.1 CDS ypdH NC_011740.1 797445 797771 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; PTS system transporter subunit IIB 797445..797771 Escherichia fergusonii ATCC 35469 7120190 YP_002381956.1 CDS ypdG NC_011740.1 797793 799040 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; PTS system transporter subunit IIC 797793..799040 Escherichia fergusonii ATCC 35469 7121743 YP_002381957.1 CDS ypdF NC_011740.1 799055 800140 D Xaa-Pro aminopeptidase; limited methionine aminopeptidase; aminopeptidase 799055..800140 Escherichia fergusonii ATCC 35469 7123917 YP_002381958.1 CDS ypdE NC_011740.1 800140 801177 D metalloprotein; exoaminopeptidase 800140..801177 Escherichia fergusonii ATCC 35469 7121742 YP_002381959.1 CDS ypdD NC_011740.1 801202 803697 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; PTS system transporter protein Hpr /enzyme I /subunit IIA 801202..803697 Escherichia fergusonii ATCC 35469 7121741 YP_002381960.1 CDS ypdC NC_011740.1 803700 804557 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding protein complement(803700..804557) Escherichia fergusonii ATCC 35469 7121740 YP_002381961.1 CDS ypdB NC_011740.1 804569 805303 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15522865; Product type pr : regulator; response regulator in two-component system with YpdA complement(804569..805303) Escherichia fergusonii ATCC 35469 7123916 YP_002381962.1 CDS ypdA NC_011740.1 805318 807015 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15522865; Product type prc : receptor; sensory kinase in two-component system with YpdB complement(805318..807015) Escherichia fergusonii ATCC 35469 7121739 YP_002381963.1 CDS yfdZ NC_011740.1 807392 808630 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; aminotransferase 807392..808630 Escherichia fergusonii ATCC 35469 7121738 YP_002381964.1 CDS ddg NC_011740.1 809118 810044 R Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(palmitoleoyl)-lipid IVA in cells subjected to cold shock; lipid A biosynthesis palmitoleoyl acyltransferase complement(809118..810044) Escherichia fergusonii ATCC 35469 7121444 YP_002381965.1 CDS EFER_0791 NC_011740.1 810411 810659 D hypothetical protein 810411..810659 Escherichia fergusonii ATCC 35469 7122151 YP_002381966.1 CDS EFER_0792 NC_011740.1 810785 812170 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; tartrate transporter complement(810785..812170) Escherichia fergusonii ATCC 35469 7120222 YP_002381967.1 CDS EFER_0793 NC_011740.1 812457 812930 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional repressor of for multidrug resistance pump (MarR family) 812457..812930 Escherichia fergusonii ATCC 35469 7123123 YP_002381968.1 CDS EFER_0794 NC_011740.1 813253 814383 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; amidase 813253..814383 Escherichia fergusonii ATCC 35469 7120223 YP_002381969.1 CDS EFER_0795 NC_011740.1 814456 815616 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 814456..815616 Escherichia fergusonii ATCC 35469 7120224 YP_002381970.1 CDS EFER_0796 NC_011740.1 815637 815987 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 815637..815987 Escherichia fergusonii ATCC 35469 7120225 YP_002381971.1 CDS EFER_0797 NC_011740.1 815998 816510 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 815998..816510 Escherichia fergusonii ATCC 35469 7120226 YP_002381972.1 CDS EFER_0798 NC_011740.1 816522 817823 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; ring hydroxylating dioxygenase subunit alpha 816522..817823 Escherichia fergusonii ATCC 35469 7120227 YP_002381973.1 CDS EFER_0799 NC_011740.1 817793 818302 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; aromatic-ring-hydroxylating dioxygenase subunit beta 817793..818302 Escherichia fergusonii ATCC 35469 7120228 YP_002381974.1 CDS EFER_0800 NC_011740.1 818271 819053 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; 3-oxoacyl-ACP reductase 818271..819053 Escherichia fergusonii ATCC 35469 7120229 YP_002381975.1 CDS EFER_0801 NC_011740.1 819063 819995 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; vanillate O-demethylase oxidoreductase 819063..819995 Escherichia fergusonii ATCC 35469 7120230 YP_002381976.1 CDS EFER_0802 NC_011740.1 820006 820506 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; flavin:NADH reductase ycdH 820006..820506 Escherichia fergusonii ATCC 35469 7123124 YP_002381977.1 CDS EFER_0803 NC_011740.1 820527 821855 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; General substrate transporter:Major facilitator superfamily 820527..821855 Escherichia fergusonii ATCC 35469 7120231 YP_002381978.1 CDS EFER_0804 NC_011740.1 822540 824006 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 822540..824006 Escherichia fergusonii ATCC 35469 7120232 YP_002381979.1 CDS EFER_0805 NC_011740.1 824270 824551 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; Ogr family transcription activator complement(824270..824551) Escherichia fergusonii ATCC 35469 7120233 YP_002381980.1 CDS EFER_0806 NC_011740.1 824548 825099 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3295254; Product type h : extrachromosomal origin; polarity suppression protein from phage origin complement(824548..825099) Escherichia fergusonii ATCC 35469 7120234 YP_002381981.1 CDS EFER_0807 NC_011740.1 825096 825839 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3295254; Product type ps : structure; capsid morphogenesis protein from phage complement(825096..825839) Escherichia fergusonii ATCC 35469 7123665 YP_002381982.1 CDS EFER_0808 NC_011740.1 826240 828912 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; inner membrane protein from phage origin complement(826240..828912) Escherichia fergusonii ATCC 35469 7123666 YP_002381983.1 CDS EFER_0809 NC_011740.1 828909 829292 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(828909..829292) Escherichia fergusonii ATCC 35469 7120235 YP_002381984.1 CDS EFER_0810 NC_011740.1 829289 829573 R Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein complement(829289..829573) Escherichia fergusonii ATCC 35469 7120236 YP_002381985.1 CDS EFER_0811 NC_011740.1 829605 829994 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(829605..829994) Escherichia fergusonii ATCC 35469 7120237 YP_002381986.1 CDS EFER_0812 NC_011740.1 829957 830187 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Phage immunity repressor protein (fragment) complement(829957..830187) Escherichia fergusonii ATCC 35469 7123125 YP_002381987.1 CDS EFER_0813 NC_011740.1 830250 830444 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 830250..830444 Escherichia fergusonii ATCC 35469 7120238 YP_002381988.1 CDS EFER_0814 NC_011740.1 830494 830709 R Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein complement(830494..830709) Escherichia fergusonii ATCC 35469 7120239 YP_002381989.1 CDS EFER_0815 NC_011740.1 830812 831693 R Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein complement(830812..831693) Escherichia fergusonii ATCC 35469 7120240 YP_002381990.1 CDS int NC_011740.1 831724 833058 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; phage integrase complement(831724..833058) Escherichia fergusonii ATCC 35469 7120241 YP_002381991.1 CDS yfdC NC_011740.1 833333 834274 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(833333..834274) Escherichia fergusonii ATCC 35469 7120083 YP_002381992.1 CDS vacJ NC_011740.1 834563 835318 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8145644, 15352239; Product type lp : lipoprotein; lipoprotein 834563..835318 Escherichia fergusonii ATCC 35469 7123057 YP_002381993.1 CDS fadL NC_011740.1 835398 836771 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15178802, 2840553, 3286621, 91100327, 1987139, 9119048; Product type t : transporter; long-chain fatty acid outer membrane transporter complement(835398..836771) Escherichia fergusonii ATCC 35469 7122655 YP_002381994.1 CDS yfcZ NC_011740.1 837087 837395 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 837087..837395 Escherichia fergusonii ATCC 35469 7123084 YP_002381995.1 CDS fadI NC_011740.1 837734 839044 D FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth; 3-ketoacyl-CoA thiolase 837734..839044 Escherichia fergusonii ATCC 35469 7123056 YP_002381996.1 CDS fadJ NC_011740.1 839044 841188 D multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate; multifunctional fatty acid oxidation complex subunit alpha 839044..841188 Escherichia fergusonii ATCC 35469 7119829 YP_002381997.1 CDS sixA NC_011740.1 841394 841879 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10089421, 20200300, 9489669; Product type e : enzyme; phosphohistidine phosphatase 841394..841879 Escherichia fergusonii ATCC 35469 7119828 YP_002381998.1 CDS yfcV NC_011740.1 842448 843008 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; fimbrial-like adhesin protein 842448..843008 Escherichia fergusonii ATCC 35469 7121788 YP_002381999.1 CDS EFER_0826 NC_011740.1 843083 845731 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; outer membrane usher protein yfcU 843083..845731 Escherichia fergusonii ATCC 35469 7119827 YP_002382000.1 CDS yfcS NC_011740.1 845751 846503 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; periplasmic pilus chaperone 845751..846503 Escherichia fergusonii ATCC 35469 7123126 YP_002382001.1 CDS yfcR NC_011740.1 846519 847034 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; fimbrial-like adhesin protein 846519..847034 Escherichia fergusonii ATCC 35469 7119826 YP_002382002.1 CDS yfcQ NC_011740.1 847031 847519 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; fimbrial-like adhesin protein 847031..847519 Escherichia fergusonii ATCC 35469 7119825 YP_002382003.1 CDS yfcP NC_011740.1 847516 848055 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; fimbrial-like adhesin protein 847516..848055 Escherichia fergusonii ATCC 35469 7119824 YP_002382004.1 CDS yfcO NC_011740.1 848042 848881 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 848042..848881 Escherichia fergusonii ATCC 35469 7119823 YP_002382005.1 CDS yfcN NC_011740.1 848936 849487 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(848936..849487) Escherichia fergusonii ATCC 35469 7123599 YP_002382006.1 CDS prmB NC_011740.1 849652 850584 D involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 849652..850584 Escherichia fergusonii ATCC 35469 7119822 YP_002382007.1 CDS aroC NC_011740.1 850619 851704 D catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 850619..851704 Escherichia fergusonii ATCC 35469 7123648 YP_002382008.1 CDS mepA NC_011740.1 851707 852531 D D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase 851707..852531 Escherichia fergusonii ATCC 35469 7123717 YP_002382009.1 CDS yfcA NC_011740.1 852531 853340 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 852531..853340 Escherichia fergusonii ATCC 35469 7120914 YP_002382010.1 CDS yfcM NC_011740.1 853340 853888 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 853340..853888 Escherichia fergusonii ATCC 35469 7119816 YP_002382011.1 CDS yfcL NC_011740.1 853922 854200 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 853922..854200 Escherichia fergusonii ATCC 35469 7119821 YP_002382012.1 CDS mnmC NC_011740.1 854256 856262 R catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules; 5-methylaminomethyl-2-thiouridine methyltransferase complement(854256..856262) Escherichia fergusonii ATCC 35469 7123598 YP_002382013.1 CDS fabB NC_011740.1 856421 857641 D FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 856421..857641 Escherichia fergusonii ATCC 35469 7122160 YP_002382014.1 CDS yfcJ NC_011740.1 857874 859052 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; hypothetical protein 857874..859052 Escherichia fergusonii ATCC 35469 7119979 YP_002382015.1 CDS flk NC_011740.1 859049 860056 R in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein; flagella biosynthesis regulator complement(859049..860056) Escherichia fergusonii ATCC 35469 7123597 YP_002382016.1 CDS pdxB NC_011740.1 860153 861289 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90036695, 91035267, 2681152, 2991861, 3029016; Product type e : enzyme; erythronate-4-phosphate dehydrogenase 860153..861289 Escherichia fergusonii ATCC 35469 7122997 YP_002382017.1 CDS usg NC_011740.1 861355 862368 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 92380957, 92380982, 93123150, 2681152, 2991861, 3029016; Product type pe : enzyme; semialdehyde dehydrogenase 861355..862368 Escherichia fergusonii ATCC 35469 7122572 YP_002382018.1 CDS truA NC_011740.1 862368 863180 D mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 862368..863180 Escherichia fergusonii ATCC 35469 7122642 YP_002382019.1 CDS dedA NC_011740.1 863263 863922 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3029016, 3040734, 7678242; Product type pm : membrane component; hypothetical protein 863263..863922 Escherichia fergusonii ATCC 35469 7122169 YP_002382020.1 CDS accD NC_011740.1 864078 864992 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 864078..864992 Escherichia fergusonii ATCC 35469 7122882 YP_002382021.1 CDS folC NC_011740.1 865062 866330 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3040739, 91112811, 92041808, 1989505, 3040734; Product type e : enzyme; bifunctional folylpolyglutamate synthase/dihydrofolate synthase 865062..866330 Escherichia fergusonii ATCC 35469 7122256 YP_002382022.1 CDS dedD NC_011740.1 866302 866970 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3040734; hypothetical protein 866302..866970 Escherichia fergusonii ATCC 35469 7123570 YP_002382023.1 CDS cvpA NC_011740.1 867229 867717 D membrane protein required for colicin V production; colicin V production protein 867229..867717 Escherichia fergusonii ATCC 35469 7122883 YP_002382024.1 CDS purF NC_011740.1 867754 869271 D Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 867754..869271 Escherichia fergusonii ATCC 35469 7122834 YP_002382025.1 CDS ubiX NC_011740.1 869366 869935 D catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 869366..869935 Escherichia fergusonii ATCC 35469 7122322 YP_002382026.1 CDS argT NC_011740.1 870200 870982 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 4583243, 87308226, 3040734, 9298646; Product type t : transporter; lysine/arginine/ornithine ABC transporter periplasmic-binding protein 870200..870982 Escherichia fergusonii ATCC 35469 7122621 YP_002382027.1 CDS hisJ NC_011740.1 871205 871987 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10373434, 6449635, 8161536, 9298646, 9600841, 9740056; Product type t : transporter; histidine/lysine/arginine/ornithine ABC transporter periplasmic-binding protein 871205..871987 Escherichia fergusonii ATCC 35469 7120544 YP_002382028.1 CDS hisQ NC_011740.1 872077 872763 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10373434; Product type t : transporter; histidine/lysine/arginine/ornithine ABC transporter membrane protein 872077..872763 Escherichia fergusonii ATCC 35469 7122200 YP_002382029.1 CDS hisM NC_011740.1 872760 873476 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10373434, 3313284; Product type t : transporter; histidine/lysine/arginine/ornithine ABC transporter membrane protein 872760..873476 Escherichia fergusonii ATCC 35469 7123443 YP_002382030.1 CDS hisP NC_011740.1 873484 874257 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10373434, 3313284, 91060556; Product type t : transporter; histidine/lysine/arginine/ornithine transporter subunit 873484..874257 Escherichia fergusonii ATCC 35469 7122201 YP_002382031.1 CDS yfcI NC_011740.1 874454 875356 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transposase 874454..875356 Escherichia fergusonii ATCC 35469 7122202 YP_002382032.1 CDS yfcH NC_011740.1 875404 876297 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pe : enzyme; hypothetical protein complement(875404..876297) Escherichia fergusonii ATCC 35469 7119820 YP_002382033.1 CDS folX NC_011740.1 876318 876680 R catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate; D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase complement(876318..876680) Escherichia fergusonii ATCC 35469 7119819 YP_002382034.1 CDS yfcG NC_011740.1 876737 877384 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; glutathione S-transferase complement(876737..877384) Escherichia fergusonii ATCC 35469 7123007 YP_002382035.1 CDS yfcF NC_011740.1 877446 878165 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 877446..878165 Escherichia fergusonii ATCC 35469 7119818 YP_002382036.1 CDS yfcE NC_011740.1 878218 878772 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; phosphodiesterase 878218..878772 Escherichia fergusonii ATCC 35469 7119817 YP_002382037.1 CDS yfcD NC_011740.1 878732 879385 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16430214; Product type pe : enzyme; NUDIX hydrolase 878732..879385 Escherichia fergusonii ATCC 35469 7123596 YP_002382038.1 CDS EFER_0865 NC_011740.1 879387 880406 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15223311, 99061204; Product type pr : regulator; transcriptional regulator with PLP domain complement(879387..880406) Escherichia fergusonii ATCC 35469 7123055 YP_002382039.1 CDS EFER_0866 NC_011740.1 880656 881099 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; phosphotransferase enzyme IIA component 880656..881099 Escherichia fergusonii ATCC 35469 7120242 YP_002382040.1 CDS EFER_0867 NC_011740.1 881167 881451 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; phosphotransferase transport system, IIB component 881167..881451 Escherichia fergusonii ATCC 35469 7123667 YP_002382041.1 CDS ulaA NC_011740.1 881468 882862 D membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 881468..882862 Escherichia fergusonii ATCC 35469 7123668 YP_002382042.1 CDS EFER_0869 NC_011740.1 882859 883689 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; carbohydrate degradation enzyme 882859..883689 Escherichia fergusonii ATCC 35469 7120243 YP_002382043.1 CDS EFER_0870 NC_011740.1 883682 884635 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; carbohydrate degradation enzyme 883682..884635 Escherichia fergusonii ATCC 35469 7120244 YP_002382044.1 CDS pta NC_011740.1 884715 886859 R catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase complement(884715..886859) Escherichia fergusonii ATCC 35469 7120245 YP_002382045.1 CDS ackA NC_011740.1 886936 888138 R AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase complement(886936..888138) Escherichia fergusonii ATCC 35469 7122311 YP_002382046.1 CDS EFER_0873 NC_011740.1 888310 888486 R hypothetical protein complement(888310..888486) Escherichia fergusonii ATCC 35469 7123452 YP_002382047.1 CDS yfbV NC_011740.1 888477 888932 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 888477..888932 Escherichia fergusonii ATCC 35469 7120246 YP_002382048.1 CDS yfbU NC_011740.1 888996 889511 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 888996..889511 Escherichia fergusonii ATCC 35469 7119814 YP_002382049.1 CDS yfbT NC_011740.1 889522 890172 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; phosphatase 889522..890172 Escherichia fergusonii ATCC 35469 7119813 YP_002382050.1 CDS yfbS NC_011740.1 890259 892091 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter 890259..892091 Escherichia fergusonii ATCC 35469 7123054 YP_002382051.1 CDS yfbR NC_011740.1 892131 892850 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15489502; Product type e : enzyme; deoxyribonucleoside 5'-monophosphatase complement(892131..892850) Escherichia fergusonii ATCC 35469 7123053 YP_002382052.1 CDS yfbQ NC_011740.1 892816 894033 R broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT complement(892816..894033) Escherichia fergusonii ATCC 35469 7119812 YP_002382053.1 CDS lrhA NC_011740.1 894966 895904 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12123461, 9882671, 7565112; Product type r : regulator; flagellar, motility and chemotaxis genes DNA-binding transcriptional repressor 894966..895904 Escherichia fergusonii ATCC 35469 7119811 YP_002382054.1 CDS nuoA NC_011740.1 896521 896964 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A 896521..896964 Escherichia fergusonii ATCC 35469 7121205 YP_002382055.1 CDS nuoB NC_011740.1 896980 897642 D The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 896980..897642 Escherichia fergusonii ATCC 35469 7119674 YP_002382056.1 CDS nuoC NC_011740.1 897736 899538 D NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms; NADH:ubiquinone oxidoreductase subunit C/D 897736..899538 Escherichia fergusonii ATCC 35469 7119675 YP_002382057.1 CDS nuoE NC_011740.1 899541 900041 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 899541..900041 Escherichia fergusonii ATCC 35469 7123574 YP_002382058.1 CDS nuoF NC_011740.1 900038 901375 D shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F 900038..901375 Escherichia fergusonii ATCC 35469 7123575 YP_002382059.1 CDS nuoG NC_011740.1 901422 904154 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 901422..904154 Escherichia fergusonii ATCC 35469 7119676 YP_002382060.1 CDS nuoH NC_011740.1 904151 905128 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 904151..905128 Escherichia fergusonii ATCC 35469 7119677 YP_002382061.1 CDS nuoI NC_011740.1 905143 905685 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 905143..905685 Escherichia fergusonii ATCC 35469 7119678 YP_002382062.1 CDS nuoJ NC_011740.1 905697 906251 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 905697..906251 Escherichia fergusonii ATCC 35469 7119679 YP_002382063.1 CDS nuoK NC_011740.1 906248 906550 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 906248..906550 Escherichia fergusonii ATCC 35469 7123030 YP_002382064.1 CDS nuoL NC_011740.1 906547 908388 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 906547..908388 Escherichia fergusonii ATCC 35469 7119680 YP_002382065.1 CDS nuoM NC_011740.1 908552 910081 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 908552..910081 Escherichia fergusonii ATCC 35469 7119681 YP_002382066.1 CDS nuoN NC_011740.1 910268 911545 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 910268..911545 Escherichia fergusonii ATCC 35469 7123031 YP_002382067.1 CDS EFER_0895 NC_011740.1 911688 912404 D hypothetical protein 911688..912404 Escherichia fergusonii ATCC 35469 7119682 YP_002382068.1 CDS EFER_0896 NC_011740.1 912399 912974 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(912399..912974) Escherichia fergusonii ATCC 35469 7120247 YP_002382069.1 CDS yfbM NC_011740.1 913126 913629 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(913126..913629) Escherichia fergusonii ATCC 35469 7120248 YP_002382070.1 CDS EFER_0898 NC_011740.1 913983 915614 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 913983..915614 Escherichia fergusonii ATCC 35469 7119810 YP_002382071.1 CDS EFER_0899 NC_011740.1 915671 916705 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; chemotaxis protein (cheV-like) complement(915671..916705) Escherichia fergusonii ATCC 35469 7123127 YP_002382072.1 CDS elaC NC_011740.1 916717 917679 R member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z complement(916717..917679) Escherichia fergusonii ATCC 35469 7123128 YP_002382073.1 CDS elaA NC_011740.1 917700 918161 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 917700..918161 Escherichia fergusonii ATCC 35469 7122944 YP_002382074.1 CDS elaB NC_011740.1 918216 918521 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 918216..918521 Escherichia fergusonii ATCC 35469 7122942 YP_002382075.1 CDS menF NC_011740.1 918615 919910 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9150206, 96140724, 2666397, 7984428, 8549818, 8764478; Product type e : enzyme; isochorismate synthase 2 918615..919910 Escherichia fergusonii ATCC 35469 7122943 YP_002382076.1 CDS menD NC_011740.1 919999 921669 D SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 919999..921669 Escherichia fergusonii ATCC 35469 7123775 YP_002382077.1 CDS yfbB NC_011740.1 921666 922424 D catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; acyl-CoA thioester hydrolase YfbB 921666..922424 Escherichia fergusonii ATCC 35469 7121259 YP_002382078.1 CDS menB NC_011740.1 922439 923296 D catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; naphthoate synthase 922439..923296 Escherichia fergusonii ATCC 35469 7119807 YP_002382079.1 CDS menC NC_011740.1 923296 924258 D catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate; O-succinylbenzoate synthase 923296..924258 Escherichia fergusonii ATCC 35469 7121257 YP_002382080.1 CDS menE NC_011740.1 924255 925610 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96186953, 8626063; Product type e : enzyme; O-succinylbenzoic acid--CoA ligase 924255..925610 Escherichia fergusonii ATCC 35469 7121258 YP_002382081.1 CDS pmrD NC_011740.1 925723 925989 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96015440, 15569938; Product type pt : transporter; polymyxin resistance protein B 925723..925989 Escherichia fergusonii ATCC 35469 7121260 YP_002382082.1 CDS EFER_0910 NC_011740.1 925983 926651 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(925983..926651) Escherichia fergusonii ATCC 35469 7120091 YP_002382083.1 CDS yfbW NC_011740.1 926369 926704 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(926369..926704) Escherichia fergusonii ATCC 35469 7120249 YP_002382084.1 CDS arnT NC_011740.1 926701 928383 R catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A; 4-amino-4-deoxy-L-arabinose transferase complement(926701..928383) Escherichia fergusonii ATCC 35469 7119815 YP_002382085.1 CDS yfbH NC_011740.1 928353 929255 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(928353..929255) Escherichia fergusonii ATCC 35469 7123715 YP_002382086.1 CDS yfbG NC_011740.1 929252 931234 R Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains; bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase complement(929252..931234) Escherichia fergusonii ATCC 35469 7119809 YP_002382087.1 CDS yfbF NC_011740.1 931234 932214 R catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate; undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase complement(931234..932214) Escherichia fergusonii ATCC 35469 7123595 YP_002382088.1 CDS yfbE NC_011740.1 932218 933357 R catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose; UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase complement(932218..933357) Escherichia fergusonii ATCC 35469 7123052 YP_002382089.1 CDS ais NC_011740.1 933688 934269 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 933688..934269 Escherichia fergusonii ATCC 35469 7119808 YP_002382090.1 CDS yfaO NC_011740.1 934309 934734 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16430214; Product type pe : enzyme; NUDIX hydrolase complement(934309..934734) Escherichia fergusonii ATCC 35469 7122290 YP_002382091.1 CDS yfaZ NC_011740.1 934964 935506 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; outer membrane porin protein 934964..935506 Escherichia fergusonii ATCC 35469 7123051 YP_002382092.1 CDS yfaY NC_011740.1 935606 936808 D Evidence 4 : Homologs of previously reported genes of unknown function; competence damage-inducible protein A 935606..936808 Escherichia fergusonii ATCC 35469 7119806 YP_002382093.1 CDS EFER_0921 NC_011740.1 937027 937374 D hypothetical protein 937027..937374 Escherichia fergusonii ATCC 35469 7119805 YP_002382094.1 CDS yfaD NC_011740.1 937416 938342 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(937416..938342) Escherichia fergusonii ATCC 35469 7120250 YP_002382095.1 CDS glpC NC_011740.1 938536 939726 R anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate; sn-glycerol-3-phosphate dehydrogenase subunit C complement(938536..939726) Escherichia fergusonii ATCC 35469 7119802 YP_002382096.1 CDS glpB NC_011740.1 939723 940982 R sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters; anaerobic glycerol-3-phosphate dehydrogenase subunit B complement(939723..940982) Escherichia fergusonii ATCC 35469 7120205 YP_002382097.1 CDS glpA NC_011740.1 940972 942600 R anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor; sn-glycerol-3-phosphate dehydrogenase subunit A complement(940972..942600) Escherichia fergusonii ATCC 35469 7120204 YP_002382098.1 CDS glpT NC_011740.1 942870 944228 D catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell; sn-glycerol-3-phosphate transporter 942870..944228 Escherichia fergusonii ATCC 35469 7120203 YP_002382099.1 CDS glpQ NC_011740.1 944176 945312 D hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic; glycerophosphodiester phosphodiesterase 944176..945312 Escherichia fergusonii ATCC 35469 7120580 YP_002382100.1 CDS inaA NC_011740.1 945464 946114 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 92165728, 1537798, 6087316; hypothetical protein 945464..946114 Escherichia fergusonii ATCC 35469 7120579 YP_002382101.1 CDS yfaE NC_011740.1 946167 946421 R plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases; 2Fe-2S ferredoxin complement(946167..946421) Escherichia fergusonii ATCC 35469 7120737 YP_002382102.1 CDS nrdB NC_011740.1 946421 947551 R B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta complement(946421..947551) Escherichia fergusonii ATCC 35469 7119803 YP_002382103.1 CDS nrdA NC_011740.1 947614 949899 R Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha complement(947614..949899) Escherichia fergusonii ATCC 35469 7119659 YP_002382104.1 CDS yfaL NC_011740.1 950582 954346 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15659678; Product type f : factor; adhesin 950582..954346 Escherichia fergusonii ATCC 35469 7119658 YP_002382105.1 CDS ubiG NC_011740.1 954487 955209 R Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase complement(954487..955209) Escherichia fergusonii ATCC 35469 7119804 YP_002382106.1 CDS gyrA NC_011740.1 955356 957992 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 955356..957992 Escherichia fergusonii ATCC 35469 7124072 YP_002382107.1 CDS atoB NC_011740.1 958103 959287 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 73032600, 87083402; Product type c : carrier; acetyl-CoA acetyltransferase complement(958103..959287) Escherichia fergusonii ATCC 35469 7123191 YP_002382108.1 CDS atoE NC_011740.1 959313 960635 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 73032600, 87083402; Product type t : transporter; short chain fatty acid transporter complement(959313..960635) Escherichia fergusonii ATCC 35469 7121628 YP_002382109.1 CDS atoA NC_011740.1 960632 961282 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 73032600, 87083402; Product type c : carrier; acetyl-CoA:acetoacetyl-CoA transferase subunit beta complement(960632..961282) Escherichia fergusonii ATCC 35469 7121631 YP_002382110.1 CDS atoD NC_011740.1 961282 961944 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 73032600, 87083402; Product type c : carrier; acetyl-CoA:acetoacetyl-CoA transferase subunit alpha complement(961282..961944) Escherichia fergusonii ATCC 35469 7121627 YP_002382111.1 CDS atoS NC_011740.1 963531 965357 R with AtoC is a member of a two-component regulatory system involved in the transcriptional regulation of the ato genes for acetoacetate metabolism; sensory histidine kinase AtoS complement(963531..965357) Escherichia fergusonii ATCC 35469 7121630 YP_002382112.1 CDS rcsC NC_011740.1 965524 968373 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11758943, 12864862, 14651646, 20032358, 21450811, 88227838, 90130299, 92048476, 9209051, 2404948, 8366025; Product type r : regulator; hybrid sensory kinase in two-component regulatory system with RcsB and YojN 965524..968373 Escherichia fergusonii ATCC 35469 7121632 YP_002382113.1 CDS rcsB NC_011740.1 968457 969107 R two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF; transcriptional regulator RcsB complement(968457..969107) Escherichia fergusonii ATCC 35469 7122354 YP_002382114.1 CDS rcsD NC_011740.1 969124 971997 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11758943, 12864862, 21206231, 2404948, 7984428; Product type r : regulator; phosphotransfer intermediate protein in two-component regulatory system with RcsBC complement(969124..971997) Escherichia fergusonii ATCC 35469 7122353 YP_002382115.1 CDS ompC NC_011740.1 972532 973653 D allows for ions and hydrophilic solutes to cross the outer membrane; outer membrane porin protein C 972532..973653 Escherichia fergusonii ATCC 35469 7120932 YP_002382116.1 CDS yojL NC_011740.1 973776 974831 D catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway; thiamine biosynthesis lipoprotein ApbE 973776..974831 Escherichia fergusonii ATCC 35469 7119692 YP_002382117.1 CDS ada NC_011740.1 974905 975969 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91073391, 93272965, 94252990; Product type r : regulator; bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase 974905..975969 Escherichia fergusonii ATCC 35469 7123915 YP_002382118.1 CDS alkB NC_011740.1 975969 976619 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12226668, 12517444, 12862460, 14527653, 87057220, 88151899, 92017669, 3536913, 3887409, 7928996; Product type e : enzyme; oxidative demethylase 975969..976619 Escherichia fergusonii ATCC 35469 7122271 YP_002382119.1 CDS yojI NC_011740.1 976695 978338 D efflux pump for the antibacterial peptide microcin J25; multidrug transporter membrane protein/ATP-binding protein 976695..978338 Escherichia fergusonii ATCC 35469 7123458 YP_002382120.1 CDS mqo NC_011740.1 978553 980199 D malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; malate:quinone oxidoreductase 978553..980199 Escherichia fergusonii ATCC 35469 7121737 YP_002382121.1 CDS glnQ NC_011740.1 980282 981004 R similar to ATP-binding component of ABC transporters; glutamine ABC transporter ATP-binding protein complement(980282..981004) Escherichia fergusonii ATCC 35469 7120962 YP_002382122.1 CDS glnP NC_011740.1 981001 981660 R similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine; glutamine ABC transporter permease complement(981001..981660) Escherichia fergusonii ATCC 35469 7120201 YP_002382123.1 CDS glnH NC_011740.1 981754 982500 R similar to periplasmic-binding component of ABC transporters; glutamine ABC transporter periplasmic protein complement(981754..982500) Escherichia fergusonii ATCC 35469 7120200 YP_002382124.1 CDS dps NC_011740.1 982907 983410 R binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps complement(982907..983410) Escherichia fergusonii ATCC 35469 7123120 YP_002382125.1 CDS rhtA NC_011740.1 983699 984586 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12648727, 8021175; Product type t : transporter; threonine and homoserine efflux system complement(983699..984586) Escherichia fergusonii ATCC 35469 7122920 YP_002382126.1 CDS ompX NC_011740.1 984937 985452 D OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains; outer membrane protein X 984937..985452 Escherichia fergusonii ATCC 35469 7121402 YP_002382127.1 CDS ybiP NC_011740.1 985520 987127 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16514146; Product type pe : enzyme; hypothetical protein complement(985520..987127) Escherichia fergusonii ATCC 35469 7119695 YP_002382128.1 CDS EFER_0959 NC_011740.1 987371 987499 R Evidence 6 : Doubtful CDS; hypothetical protein complement(987371..987499) Escherichia fergusonii ATCC 35469 7123426 YP_002382129.1 CDS mntR NC_011740.1 987685 988152 D Transcriptional regulator that represses the manganese transporter MntH when manganese is present; manganese transport regulator MntR 987685..988152 Escherichia fergusonii ATCC 35469 7123279 YP_002382130.1 CDS ybiR NC_011740.1 988149 989264 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter 988149..989264 Escherichia fergusonii ATCC 35469 7120945 YP_002382131.1 CDS ybiS NC_011740.1 989324 990244 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10493123, 9298646; hypothetical protein complement(989324..990244) Escherichia fergusonii ATCC 35469 7123427 YP_002382132.1 CDS ybiT NC_011740.1 990463 992055 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11916677; Product type pt : transporter; ABC transporter ATP-binding protein 990463..992055 Escherichia fergusonii ATCC 35469 7122101 YP_002382133.1 CDS ybiV NC_011740.1 992254 993069 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15657928; Product type e : enzyme; type II HAD phosphatase complement(992254..993069) Escherichia fergusonii ATCC 35469 7123979 YP_002382134.1 CDS ybiW NC_011740.1 993215 995647 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16218870; Product type pe : enzyme; glycyl radical cofactor protein complement(993215..995647) Escherichia fergusonii ATCC 35469 7122102 YP_002382135.1 CDS ybiY NC_011740.1 995653 996579 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15581584; Product type pe : enzyme; AdoMet-dependent glycyl radical activating enzyme complement(995653..996579) Escherichia fergusonii ATCC 35469 7122103 YP_002382136.1 CDS fsaA NC_011740.1 996683 997345 D similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 996683..997345 Escherichia fergusonii ATCC 35469 7122105 YP_002382137.1 CDS moeB NC_011740.1 997432 998181 R ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB complement(997432..998181) Escherichia fergusonii ATCC 35469 7124144 YP_002382138.1 CDS moeA NC_011740.1 998181 999416 R is involved in the formation of active molybdenum cofactor and the chelation of molybdenum; molybdopterin biosynthesis protein MoeA complement(998181..999416) Escherichia fergusonii ATCC 35469 7123781 YP_002382139.1 CDS yliA NC_011740.1 999629 1001521 D with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains; glutathione transporter ATP-binding protein 999629..1001521 Escherichia fergusonii ATCC 35469 7120954 YP_002382140.1 CDS yliB NC_011740.1 1001548 1003086 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 17366475; Product type pt : transporter; peptide ABC transporter substrate-binding protein 1001548..1003086 Escherichia fergusonii ATCC 35469 7122044 YP_002382141.1 CDS yliC NC_011740.1 1003106 1004026 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; peptide ABC transporter permease 1003106..1004026 Escherichia fergusonii ATCC 35469 7122045 YP_002382142.1 CDS yliD NC_011740.1 1004029 1004940 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; peptide ABC transporter permease 1004029..1004940 Escherichia fergusonii ATCC 35469 7122046 YP_002382143.1 CDS EFER_0974 NC_011740.1 1005071 1007419 D hypothetical protein 1005071..1007419 Escherichia fergusonii ATCC 35469 7122047 YP_002382144.1 CDS yliF NC_011740.1 1007429 1008757 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; diguanylate cyclase 1007429..1008757 Escherichia fergusonii ATCC 35469 7120252 YP_002382145.1 CDS rimO NC_011740.1 1008798 1010123 R catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; 30S ribosomal protein S12 methylthiotransferase complement(1008798..1010123) Escherichia fergusonii ATCC 35469 7122048 YP_002382146.1 CDS bssR NC_011740.1 1010351 1010734 D BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssR 1010351..1010734 Escherichia fergusonii ATCC 35469 7123416 YP_002382147.1 CDS yliI NC_011740.1 1010836 1011948 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16522795, 16864586; Product type e : enzyme; PQQ-dependent aldose sugar dehydrogenase 1010836..1011948 Escherichia fergusonii ATCC 35469 7121678 YP_002382148.1 CDS yliJ NC_011740.1 1011953 1012585 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; glutathione S-transferase complement(1011953..1012585) Escherichia fergusonii ATCC 35469 7122050 YP_002382149.1 CDS dacC NC_011740.1 1012826 1014028 D penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 1012826..1014028 Escherichia fergusonii ATCC 35469 7122051 YP_002382150.1 CDS deoR NC_011740.1 1014076 1014873 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89231635, 89336786, 92231401, 2994018; Product type r : regulator; DNA-binding transcriptional repressor DeoR complement(1014076..1014873) Escherichia fergusonii ATCC 35469 7122862 YP_002382151.1 CDS ybjG NC_011740.1 1014906 1015514 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15778224; Product type e : enzyme; undecaprenyl pyrophosphate phosphatase complement(1014906..1015514) Escherichia fergusonii ATCC 35469 7122890 YP_002382152.1 CDS cmr NC_011740.1 1015799 1017031 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10022825, 12578981, 14688269, 21217867, 21450803, 9079913, 9644262, 99030337, 8655497; Product type t : transporter; multidrug efflux system protein 1015799..1017031 Escherichia fergusonii ATCC 35469 7122107 YP_002382153.1 CDS ybjH NC_011740.1 1017072 1017350 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1017072..1017350) Escherichia fergusonii ATCC 35469 7120907 YP_002382154.1 CDS ybjI NC_011740.1 1017454 1018269 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15808744; Product type pe : enzyme; phosphatase complement(1017454..1018269) Escherichia fergusonii ATCC 35469 7122108 YP_002382155.1 CDS ybjJ NC_011740.1 1018269 1019477 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter complement(1018269..1019477) Escherichia fergusonii ATCC 35469 7122109 YP_002382156.1 CDS ybjK NC_011740.1 1019565 1020104 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator 1019565..1020104 Escherichia fergusonii ATCC 35469 7122110 YP_002382157.1 CDS EFER_0988 NC_011740.1 1020204 1020422 D hypothetical protein 1020204..1020422 Escherichia fergusonii ATCC 35469 7122111 YP_002382158.1 CDS EFER_0989 NC_011740.1 1020585 1020824 R hypothetical protein complement(1020585..1020824) Escherichia fergusonii ATCC 35469 7123129 YP_002382159.1 CDS ybjL NC_011740.1 1021037 1022722 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; hypothetical protein complement(1021037..1022722) Escherichia fergusonii ATCC 35469 7121171 YP_002382160.1 CDS ybjM NC_011740.1 1022991 1023380 D Evidence 2b : Function of strongly homologous gene; Product type pm : membrane component; hypothetical protein 1022991..1023380 Escherichia fergusonii ATCC 35469 7122112 YP_002382161.1 CDS nfsA NC_011740.1 1023545 1024267 D NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds; nitroreductase A 1023545..1024267 Escherichia fergusonii ATCC 35469 7122113 YP_002382162.1 CDS rimK NC_011740.1 1024317 1025219 D responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6; ribosomal protein S6 modification protein 1024317..1025219 Escherichia fergusonii ATCC 35469 7120689 YP_002382163.1 CDS ybjN NC_011740.1 1025308 1025784 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1025308..1025784 Escherichia fergusonii ATCC 35469 7121413 YP_002382164.1 CDS potF NC_011740.1 1026136 1027248 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93106992, 9651355, 9298646, 8416922; Product type t : transporter; putrescine ABC transporter periplasmic-binding protein 1026136..1027248 Escherichia fergusonii ATCC 35469 7122114 YP_002382165.1 CDS potG NC_011740.1 1027343 1028476 D part of the PotFGHI ATP-dependent putrescine transporter; putrescine ABC transporter ATP-binding protein 1027343..1028476 Escherichia fergusonii ATCC 35469 7120103 YP_002382166.1 CDS potH NC_011740.1 1028486 1029439 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93106992; Product type t : transporter; putrescine ABC transporter membrane protein 1028486..1029439 Escherichia fergusonii ATCC 35469 7123103 YP_002382167.1 CDS potI NC_011740.1 1029436 1030281 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93106992; Product type t : transporter; putrescine ABC transporter membrane protein 1029436..1030281 Escherichia fergusonii ATCC 35469 7120104 YP_002382168.1 CDS ybjO NC_011740.1 1030341 1030829 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1030341..1030829 Escherichia fergusonii ATCC 35469 7123104 YP_002382169.1 CDS rumB NC_011740.1 1030870 1031997 D RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA; 23S rRNA methyluridine methyltransferase 1030870..1031997 Escherichia fergusonii ATCC 35469 7122115 YP_002382170.1 CDS artJ NC_011740.1 1032026 1032757 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93273744, 9298646, 9600841, 8801422; Product type t : transporter; arginine ABC transporter substrate-binding protein complement(1032026..1032757) Escherichia fergusonii ATCC 35469 7121164 YP_002382171.1 CDS artM NC_011740.1 1032984 1033652 R with ArtPQJI acts to transport arginine across the inner membrane; arginine transporter permease subunit ArtM complement(1032984..1033652) Escherichia fergusonii ATCC 35469 7120557 YP_002382172.1 CDS artQ NC_011740.1 1033652 1034368 R with ArtPMJI transports arginine across the inner membrane; arginine transporter permease subunit ArtQ complement(1033652..1034368) Escherichia fergusonii ATCC 35469 7120559 YP_002382173.1 CDS artI NC_011740.1 1034375 1035106 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93273744, 9298646, 9600841, 8801422, 9740056; Product type t : transporter; arginine ABC transporter substrate-binding protein complement(1034375..1035106) Escherichia fergusonii ATCC 35469 7120560 YP_002382174.1 CDS artP NC_011740.1 1035124 1035852 R With ArtMQJI transports arginine across the inner membrane; arginine transporter ATP-binding subunit complement(1035124..1035852) Escherichia fergusonii ATCC 35469 7120556 YP_002382175.1 CDS ybjP NC_011740.1 1036070 1036585 R induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS; lipoprotein complement(1036070..1036585) Escherichia fergusonii ATCC 35469 7123180 YP_002382176.1 CDS ybjQ NC_011740.1 1036711 1037034 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1036711..1037034 Escherichia fergusonii ATCC 35469 7122116 YP_002382177.1 CDS ybjR NC_011740.1 1037031 1037861 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; cell wall amidase and lipoprotein 1037031..1037861 Escherichia fergusonii ATCC 35469 7123428 YP_002382178.1 CDS ybjS NC_011740.1 1037858 1038871 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; NAD(P)H:quinone oxidoreductase complement(1037858..1038871) Escherichia fergusonii ATCC 35469 7123429 YP_002382179.1 CDS ybjT NC_011740.1 1038970 1040400 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1038970..1040400) Escherichia fergusonii ATCC 35469 7122117 YP_002382180.1 CDS ltaE NC_011740.1 1040411 1041412 R low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine; L-threonine aldolase complement(1040411..1041412) Escherichia fergusonii ATCC 35469 7122118 YP_002382181.1 CDS poxB NC_011740.1 1041449 1043167 R catalyzes the formation of acetate from pyruvate; pyruvate dehydrogenase complement(1041449..1043167) Escherichia fergusonii ATCC 35469 7123283 YP_002382182.1 CDS EFER_1016 NC_011740.1 1043319 1043753 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1043319..1043753 Escherichia fergusonii ATCC 35469 7120105 YP_002382183.1 CDS hcr NC_011740.1 1043811 1044779 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20117674; Product type e : enzyme; HCP oxidoreductase complement(1043811..1044779) Escherichia fergusonii ATCC 35469 7123669 YP_002382184.1 CDS hcp NC_011740.1 1044791 1046443 R catalyzes the reduction of hydroxylamine to ammonia and water; hydroxylamine reductase complement(1044791..1046443) Escherichia fergusonii ATCC 35469 7120631 YP_002382185.1 CDS ybjE NC_011740.1 1046587 1047486 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter complement(1046587..1047486) Escherichia fergusonii ATCC 35469 7120630 YP_002382186.1 CDS EFER_1020 NC_011740.1 1047825 1048850 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transposase, IS110 family 1047825..1048850 Escherichia fergusonii ATCC 35469 7123980 YP_002382187.1 CDS EFER_1021 NC_011740.1 1049101 1049277 D hypothetical protein 1049101..1049277 Escherichia fergusonii ATCC 35469 7120254 YP_002382188.1 CDS aqpZ NC_011740.1 1049368 1050063 R porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; aquaporin Z complement(1049368..1050063) Escherichia fergusonii ATCC 35469 7120255 YP_002382189.1 CDS ybjD NC_011740.1 1050485 1052143 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1050485..1052143 Escherichia fergusonii ATCC 35469 7120526 YP_002382190.1 CDS EFER_1024 NC_011740.1 1052140 1053147 R hypothetical protein complement(1052140..1053147) Escherichia fergusonii ATCC 35469 7122106 YP_002382191.1 CDS EFER_1025 NC_011740.1 1053093 1053218 R hypothetical protein complement(1053093..1053218) Escherichia fergusonii ATCC 35469 7120256 YP_002382192.1 CDS macA NC_011740.1 1053252 1054367 D confers macrolide resistance via active drug efflux; macrolide transporter subunit MacA 1053252..1054367 Escherichia fergusonii ATCC 35469 7120257 YP_002382193.1 CDS macB NC_011740.1 1054364 1056310 D with MacA is involved in the export of macrolide; macrolide transporter ATP-binding /permease 1054364..1056310 Escherichia fergusonii ATCC 35469 7121219 YP_002382194.1 CDS cspD NC_011740.1 1056531 1056752 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21160192, 94293754, 97405911, 1622933, 2186030, 9868784; Product type f : factor; cold shock protein-like protein complement(1056531..1056752) Escherichia fergusonii ATCC 35469 7121220 YP_002382195.1 CDS clpS NC_011740.1 1057075 1057395 D involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 1057075..1057395 Escherichia fergusonii ATCC 35469 7122820 YP_002382196.1 CDS clpA NC_011740.1 1057411 1059705 D ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; ATP-dependent Clp protease ATP-binding subunit 1057411..1059705 Escherichia fergusonii ATCC 35469 7123240 YP_002382197.1 CDS infA NC_011740.1 1060450 1060668 R stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 complement(1060450..1060668) Escherichia fergusonii ATCC 35469 7120081 YP_002382198.1 CDS aat NC_011740.1 1060953 1061657 R leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase complement(1060953..1061657) Escherichia fergusonii ATCC 35469 7123212 YP_002382199.1 CDS cydC NC_011740.1 1061699 1063420 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein complement(1061699..1063420) Escherichia fergusonii ATCC 35469 7122252 YP_002382200.1 CDS cydD NC_011740.1 1063421 1065187 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein complement(1063421..1065187) Escherichia fergusonii ATCC 35469 7123542 YP_002382201.1 CDS trxB NC_011740.1 1065310 1066275 R catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; thioredoxin reductase complement(1065310..1066275) Escherichia fergusonii ATCC 35469 7122841 YP_002382202.1 CDS lrp NC_011740.1 1066808 1067302 D mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system; leucine-responsive transcriptional regulator 1066808..1067302 Escherichia fergusonii ATCC 35469 7122172 YP_002382203.1 CDS ftsK NC_011740.1 1067437 1071282 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10027974, 11864592, 12034757, 99047597, 10922461, 11703663, 11832210, 11948172, 7592387; Product type cp : cell process; DNA-binding membrane protein 1067437..1071282 Escherichia fergusonii ATCC 35469 7121206 YP_002382204.1 CDS lolA NC_011740.1 1071438 1072052 D participates with LolB in the incorporation of lipoprotein into the outer membrane; outer-membrane lipoprotein carrier protein 1071438..1072052 Escherichia fergusonii ATCC 35469 7123113 YP_002382205.1 CDS ycaJ NC_011740.1 1072063 1073406 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7567469, 7628437, 11459952, 11029431; Product type cp : cell process; recombination factor protein RarA 1072063..1073406 Escherichia fergusonii ATCC 35469 7123763 YP_002382206.1 CDS serS NC_011740.1 1073497 1074789 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 1073497..1074789 Escherichia fergusonii ATCC 35469 7123981 YP_002382207.1 CDS ycaC NC_011740.1 1074847 1075473 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9782055, 3062312, 11714269; Product type pe : enzyme; hydrolase complement(1074847..1075473) Escherichia fergusonii ATCC 35469 7121771 YP_002382208.1 CDS ycaD NC_011740.1 1075786 1076934 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; MFS family transporter protein 1075786..1076934 Escherichia fergusonii ATCC 35469 7122119 YP_002382209.1 CDS ycaM NC_011740.1 1077142 1078572 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15380559; Product type pt : transporter; transporter 1077142..1078572 Escherichia fergusonii ATCC 35469 7122120 YP_002382210.1 CDS pflA NC_011740.1 1078782 1079522 R activates pyruvate formate-lyase 1 under anaerobic conditions; pyruvate formate lyase-activating enzyme 1 complement(1078782..1079522) Escherichia fergusonii ATCC 35469 7122121 YP_002382211.1 CDS pflB NC_011740.1 1079715 1081997 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91064082, 92276323, 10504733, 1310545, 2651404, 3053170, 9629924; Product type e : enzyme; pyruvate formate lyase I complement(1079715..1081997) Escherichia fergusonii ATCC 35469 7123504 YP_002382212.1 CDS focA NC_011740.1 1082053 1082910 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94293770, 2651404; Product type t : transporter; formate transporter complement(1082053..1082910) Escherichia fergusonii ATCC 35469 7122583 YP_002382213.1 CDS ycaO NC_011740.1 1083315 1085075 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1083315..1085075) Escherichia fergusonii ATCC 35469 7123568 YP_002382214.1 CDS ycaP NC_011740.1 1085205 1085897 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1085205..1085897 Escherichia fergusonii ATCC 35469 7122122 YP_002382215.1 CDS serC NC_011740.1 1086087 1087175 D catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 1086087..1087175 Escherichia fergusonii ATCC 35469 7123982 YP_002382216.1 CDS aroA NC_011740.1 1087218 1088522 D catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 1087218..1088522 Escherichia fergusonii ATCC 35469 7121770 YP_002382217.1 CDS cmk NC_011740.1 1088709 1089392 D Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 1088709..1089392 Escherichia fergusonii ATCC 35469 7123716 YP_002382218.1 CDS rpsA NC_011740.1 1089503 1091176 D in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 1089503..1091176 Escherichia fergusonii ATCC 35469 7120906 YP_002382219.1 CDS ihfB NC_011740.1 1091336 1091620 D This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 1091336..1091620 Escherichia fergusonii ATCC 35469 7121126 YP_002382220.1 CDS EFER_1057 NC_011740.1 1091823 1094087 D hypothetical protein 1091823..1094087 Escherichia fergusonii ATCC 35469 7120725 YP_002382221.1 CDS msbA NC_011740.1 1094124 1095872 D involved in the transport of lipid A across the inner membrane; lipid transporter ATP-binding protein/permease 1094124..1095872 Escherichia fergusonii ATCC 35469 7120259 YP_002382222.1 CDS lpxK NC_011740.1 1095869 1096855 D transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 1095869..1096855 Escherichia fergusonii ATCC 35469 7120970 YP_002382223.1 CDS ycaQ NC_011740.1 1096892 1098124 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1096892..1098124 Escherichia fergusonii ATCC 35469 7123827 YP_002382224.1 CDS ycaR NC_011740.1 1098177 1098359 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1098177..1098359 Escherichia fergusonii ATCC 35469 7122123 YP_002382225.1 CDS kdsB NC_011740.1 1098356 1099102 D CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 1098356..1099102 Escherichia fergusonii ATCC 35469 7122124 YP_002382226.1 CDS ycbJ NC_011740.1 1099255 1100148 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1099255..1100148 Escherichia fergusonii ATCC 35469 7120809 YP_002382227.1 CDS ycbC NC_011740.1 1100125 1100904 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(1100125..1100904) Escherichia fergusonii ATCC 35469 7119899 YP_002382228.1 CDS smtA NC_011740.1 1101040 1101825 D involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA; metallothionein SmtA 1101040..1101825 Escherichia fergusonii ATCC 35469 7123983 YP_002382229.1 CDS mukF NC_011740.1 1101822 1103144 D acts with MukB and MukE to condense the chromosome and allow for segregation during cell division; condesin subunit F 1101822..1103144 Escherichia fergusonii ATCC 35469 7121796 YP_002382230.1 CDS mukE NC_011740.1 1103152 1103829 D acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; condesin subunit E 1103152..1103829 Escherichia fergusonii ATCC 35469 7120644 YP_002382231.1 CDS mukB NC_011740.1 1103829 1108289 D SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; cell division protein MukB 1103829..1108289 Escherichia fergusonii ATCC 35469 7120643 YP_002382232.1 CDS ycbB NC_011740.1 1108532 1110379 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 1108532..1110379 Escherichia fergusonii ATCC 35469 7120642 YP_002382233.1 CDS ycbK NC_011740.1 1110551 1111111 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1110551..1111111 Escherichia fergusonii ATCC 35469 7122125 YP_002382234.1 CDS ycbL NC_011740.1 1111138 1111785 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14529289; Product type pe : enzyme; metal-binding hydrolase 1111138..1111785 Escherichia fergusonii ATCC 35469 7119900 YP_002382235.1 CDS aspC NC_011740.1 1111834 1113024 R catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase complement(1111834..1113024) Escherichia fergusonii ATCC 35469 7119901 YP_002382236.1 CDS ompF NC_011740.1 1113208 1114278 R outer membrane porin F; 1a; Ia; b; outer membrane protein F complement(1113208..1114278) Escherichia fergusonii ATCC 35469 7120571 YP_002382237.1 CDS asnC NC_011740.1 1114888 1116288 R catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase complement(1114888..1116288) Escherichia fergusonii ATCC 35469 7119693 YP_002382238.1 CDS pncB NC_011740.1 1116454 1117656 R catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase complement(1116454..1117656) Escherichia fergusonii ATCC 35469 7123182 YP_002382239.1 CDS pepN NC_011740.1 1117922 1120534 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21101837, 86164315, 87163509, 2436977, 3018440; Product type e : enzyme; aminopeptidase N 1117922..1120534 Escherichia fergusonii ATCC 35469 7120092 YP_002382240.1 CDS ssuB NC_011740.1 1120577 1121344 R part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic substrate-binding subunit, SsuB the ATP-binding subunit and SsuC the permease; aliphatic sulfonates transport ATP-binding subunit complement(1120577..1121344) Escherichia fergusonii ATCC 35469 7123503 YP_002382241.1 CDS ssuC NC_011740.1 1121341 1122132 R part of the ABC type transport system for alkanesulfonate SsuABC; SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter permease complement(1121341..1122132) Escherichia fergusonii ATCC 35469 7123952 YP_002382242.1 CDS ssuD NC_011740.1 1122144 1123289 R catalyzes the release of sulfite from alkanesulfonates; alkanesulfonate monooxygenase complement(1122144..1123289) Escherichia fergusonii ATCC 35469 7121948 YP_002382243.1 CDS ssuA NC_011740.1 1123286 1124245 R part of the ABC type transport system SsuABC for aliphatic sulfonates; with SsuA being the periplasmic subunit SsuB the ATP-binding subunit and SsuC the permease; alkanesulfonate transporter substrate-binding subunit complement(1123286..1124245) Escherichia fergusonii ATCC 35469 7121949 YP_002382244.1 CDS ssuE NC_011740.1 1124238 1124813 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20245523, 99410391, 99436146, 8774726; Product type e : enzyme; NAD(P)H-dependent FMN reductase complement(1124238..1124813) Escherichia fergusonii ATCC 35469 7121947 YP_002382245.1 CDS pyrD NC_011740.1 1125050 1126060 D catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 1125050..1126060 Escherichia fergusonii ATCC 35469 7121950 YP_002382246.1 CDS ycbW NC_011740.1 1126234 1126776 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1126234..1126776 Escherichia fergusonii ATCC 35469 7122334 YP_002382247.1 CDS ycbX NC_011740.1 1126773 1127882 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1327782; Product type pe : enzyme; 2Fe-2S cluster-containing protein complement(1126773..1127882) Escherichia fergusonii ATCC 35469 7119902 YP_002382248.1 CDS rlmL NC_011740.1 1127980 1130088 D catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 1127980..1130088 Escherichia fergusonii ATCC 35469 7119903 YP_002382249.1 CDS uup NC_011740.1 1130100 1132007 D Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth; ABC transporter ATPase 1130100..1132007 Escherichia fergusonii ATCC 35469 7119904 YP_002382250.1 CDS pqiA NC_011740.1 1132137 1133384 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95270582; Product type cp : cell process; paraquat-inducible membrane protein A 1132137..1133384 Escherichia fergusonii ATCC 35469 7123512 YP_002382251.1 CDS pqiB NC_011740.1 1133389 1135029 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95270582; Product type cp : cell process; paraquat-inducible protein B 1133389..1135029 Escherichia fergusonii ATCC 35469 7120119 YP_002382252.1 CDS ymbA NC_011740.1 1135041 1135589 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1135041..1135589 Escherichia fergusonii ATCC 35469 7120120 YP_002382253.1 CDS rmf NC_011740.1 1135845 1136012 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1101029, 90207255, 2832401, 8440252; Product type f : factor; ribosome modulation factor 1135845..1136012 Escherichia fergusonii ATCC 35469 7122052 YP_002382254.1 CDS fabA NC_011740.1 1136079 1136597 R catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase complement(1136079..1136597) Escherichia fergusonii ATCC 35469 7121419 YP_002382255.1 CDS ycbZ NC_011740.1 1136666 1138426 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; ATP-dependent protease complement(1136666..1138426) Escherichia fergusonii ATCC 35469 7119978 YP_002382256.1 CDS ycbG NC_011740.1 1138611 1139066 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1138611..1139066 Escherichia fergusonii ATCC 35469 7119905 YP_002382257.1 CDS ompA NC_011740.1 1139121 1140248 R OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; outer membrane protein A complement(1139121..1140248) Escherichia fergusonii ATCC 35469 7121751 YP_002382258.1 CDS sulA NC_011740.1 1140533 1141042 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10368140, 91072263, 93163041, 98348458, 3297925, 6253901, 6306396; Product type cp : cell process; SOS cell division inhibitor complement(1140533..1141042) Escherichia fergusonii ATCC 35469 7120759 YP_002382259.1 CDS EFER_1096 NC_011740.1 1141259 1141888 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1141259..1141888 Escherichia fergusonii ATCC 35469 7121966 YP_002382260.1 CDS yccS NC_011740.1 1141851 1144064 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(1141851..1144064) Escherichia fergusonii ATCC 35469 7120260 YP_002382261.1 CDS yccF NC_011740.1 1144024 1144470 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(1144024..1144470) Escherichia fergusonii ATCC 35469 7119908 YP_002382262.1 CDS helD NC_011740.1 1144593 1146647 D catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand; DNA helicase IV 1144593..1146647 Escherichia fergusonii ATCC 35469 7123071 YP_002382263.1 CDS mgsA NC_011740.1 1146679 1147137 R catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase complement(1146679..1147137) Escherichia fergusonii ATCC 35469 7120636 YP_002382264.1 CDS yccT NC_011740.1 1147233 1147895 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1147233..1147895) Escherichia fergusonii ATCC 35469 7123778 YP_002382265.1 CDS yccU NC_011740.1 1148068 1148481 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; CoA-binding protein 1148068..1148481 Escherichia fergusonii ATCC 35469 7123072 YP_002382266.1 CDS yccV NC_011740.1 1148528 1148845 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12700277, 15569148; Product type f : factor; heat shock protein HspQ complement(1148528..1148845) Escherichia fergusonii ATCC 35469 7119909 YP_002382267.1 CDS yccW NC_011740.1 1148903 1150006 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; AdoMet-dependent methyltransferase complement(1148903..1150006) Escherichia fergusonii ATCC 35469 7119910 YP_002382268.1 CDS yccX NC_011740.1 1149975 1150466 D catalyzes the hydrolysis of acylphosphate; acylphosphatase 1149975..1150466 Escherichia fergusonii ATCC 35469 7123611 YP_002382269.1 CDS tusE NC_011740.1 1150463 1150792 R transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein TusE complement(1150463..1150792) Escherichia fergusonii ATCC 35469 7119911 YP_002382270.1 CDS yccA NC_011740.1 1150883 1151542 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 6376117; Product type m : membrane component; hypothetical protein complement(1150883..1151542) Escherichia fergusonii ATCC 35469 7122610 YP_002382271.1 CDS EFER_1108 NC_011740.1 1152124 1152885 D hypothetical protein 1152124..1152885 Escherichia fergusonii ATCC 35469 7120028 YP_002382272.1 CDS EFER_1109 NC_011740.1 1153042 1153176 R hypothetical protein complement(1153042..1153176) Escherichia fergusonii ATCC 35469 7120261 YP_002382273.1 CDS hyaA NC_011740.1 1153195 1154313 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86192450, 90202716, 92215587; Product type e : enzyme; hydrogenase 1 small subunit 1153195..1154313 Escherichia fergusonii ATCC 35469 7120262 YP_002382274.1 CDS hyaB NC_011740.1 1154310 1156103 D involved in hydrogen cycling during fermentative growth; hydrogenase 1 large subunit 1154310..1156103 Escherichia fergusonii ATCC 35469 7122235 YP_002382275.1 CDS hyaC NC_011740.1 1156122 1156829 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90202716, 91310595, 92215587; Product type c : carrier; hydrogenase 1 b-type cytochrome subunit 1156122..1156829 Escherichia fergusonii ATCC 35469 7122236 YP_002382276.1 CDS hyaD NC_011740.1 1156826 1157413 D HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1); hydrogenase 1 maturation protease 1156826..1157413 Escherichia fergusonii ATCC 35469 7124005 YP_002382277.1 CDS hyaE NC_011740.1 1157410 1157808 D involved in processing hydrogenase proteins HyaA and HyaB; hydrogenase-1 operon protein HyaE 1157410..1157808 Escherichia fergusonii ATCC 35469 7122237 YP_002382278.1 CDS hyaF NC_011740.1 1157745 1158659 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90202716, 91310595, 92215587; Product type f : factor; hydrogenase-1 nickel incorporation protein 1157745..1158659 Escherichia fergusonii ATCC 35469 7122238 YP_002382279.1 CDS yecA NC_011740.1 1158753 1159418 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1158753..1159418 Escherichia fergusonii ATCC 35469 7122239 YP_002382280.1 CDS tyrP NC_011740.1 1159458 1160696 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89008121, 2022620; Product type t : transporter; tyrosine transporter complement(1159458..1160696) Escherichia fergusonii ATCC 35469 7123883 YP_002382281.1 CDS yecH NC_011740.1 1160828 1161103 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1160828..1161103 Escherichia fergusonii ATCC 35469 7122613 YP_002382282.1 CDS ftn NC_011740.1 1161141 1161638 R cytoplasmic iron storage protein; ferritin complement(1161141..1161638) Escherichia fergusonii ATCC 35469 7121531 YP_002382283.1 CDS EFER_1120 NC_011740.1 1161768 1162103 R hypothetical protein complement(1161768..1162103) Escherichia fergusonii ATCC 35469 7120143 YP_002382284.1 CDS yecI NC_011740.1 1162249 1162752 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; ferritin-like protein complement(1162249..1162752) Escherichia fergusonii ATCC 35469 7123130 YP_002382285.1 CDS araF NC_011740.1 1163710 1164699 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89255061, 90375534, 2445996, 326784, 326785, 6885805, 7031057, 9298646; Product type t : transporter; L-arabinose ABC transporter periplasmic-binding protein 1163710..1164699 Escherichia fergusonii ATCC 35469 7121532 YP_002382286.1 CDS araG NC_011740.1 1164794 1166308 D Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter ATP-binding protein 1164794..1166308 Escherichia fergusonii ATCC 35469 7120530 YP_002382287.1 CDS araH NC_011740.1 1166323 1167309 D Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose; L-arabinose transporter permease 1166323..1167309 Escherichia fergusonii ATCC 35469 7120531 YP_002382288.1 CDS otsB NC_011740.1 1167463 1168266 D biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature; trehalose-6-phosphate phosphatase 1167463..1168266 Escherichia fergusonii ATCC 35469 7120532 YP_002382289.1 CDS otsA NC_011740.1 1168241 1169665 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92078100, 92121128, 93302496, 8045430; Product type e : enzyme; trehalose-6-phosphate synthase 1168241..1169665 Escherichia fergusonii ATCC 35469 7119705 YP_002382290.1 CDS yecG NC_011740.1 1169672 1170100 R ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspC complement(1169672..1170100) Escherichia fergusonii ATCC 35469 7119704 YP_002382291.1 CDS flhD NC_011740.1 1170810 1171268 D with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems; transcriptional activator FlhD 1170810..1171268 Escherichia fergusonii ATCC 35469 7121530 YP_002382292.1 CDS flhC NC_011740.1 1171271 1171849 D With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems; transcriptional activator FlhC 1171271..1171849 Escherichia fergusonii ATCC 35469 7122981 YP_002382293.1 CDS motA NC_011740.1 1171973 1172860 D With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 1171973..1172860 Escherichia fergusonii ATCC 35469 7122980 YP_002382294.1 CDS motB NC_011740.1 1172857 1173771 D with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB 1172857..1173771 Escherichia fergusonii ATCC 35469 7120957 YP_002382295.1 CDS cheA NC_011740.1 1173716 1175731 D chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component; chemotaxis protein CheA 1173716..1175731 Escherichia fergusonii ATCC 35469 7123782 YP_002382296.1 CDS cheW NC_011740.1 1175748 1176242 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91126073, 91296802, 91317710, 2002011, 3510184; Product type r : regulator; purine-binding chemotaxis protein 1175748..1176242 Escherichia fergusonii ATCC 35469 7120886 YP_002382297.1 CDS EFER_1135 NC_011740.1 1176461 1177081 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; Type I pilus protein CsuA/B 1176461..1177081 Escherichia fergusonii ATCC 35469 7120888 YP_002382298.1 CDS EFER_1136 NC_011740.1 1177094 1177633 D hypothetical protein 1177094..1177633 Escherichia fergusonii ATCC 35469 7123670 YP_002382299.1 CDS EFER_1137 NC_011740.1 1177646 1178392 D hypothetical protein 1177646..1178392 Escherichia fergusonii ATCC 35469 7120263 YP_002382300.1 CDS EFER_1138 NC_011740.1 1178368 1180755 D hypothetical protein 1178368..1180755 Escherichia fergusonii ATCC 35469 7120264 YP_002382301.1 CDS EFER_1139 NC_011740.1 1180652 1180954 R hypothetical protein complement(1180652..1180954) Escherichia fergusonii ATCC 35469 7120265 YP_002382302.1 CDS EFER_1140 NC_011740.1 1180737 1181711 D hypothetical protein 1180737..1181711 Escherichia fergusonii ATCC 35469 7120266 YP_002382303.1 CDS tar NC_011740.1 1181771 1183336 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90094243, 92165727, 6305515, 9315712; Product type r : regulator; methyl-accepting chemotaxis protein II 1181771..1183336 Escherichia fergusonii ATCC 35469 7120267 YP_002382304.1 CDS cheR NC_011740.1 1183356 1184222 D methylates the MCP; chemotaxis methyltransferase CheR 1183356..1184222 Escherichia fergusonii ATCC 35469 7123956 YP_002382305.1 CDS cheB NC_011740.1 1184219 1185268 D regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis-specific methylesterase 1184219..1185268 Escherichia fergusonii ATCC 35469 7120887 YP_002382306.1 CDS cheY NC_011740.1 1185283 1185672 D chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble; chemotaxis regulatory protein CheY 1185283..1185672 Escherichia fergusonii ATCC 35469 7123235 YP_002382307.1 CDS cheZ NC_011740.1 1185680 1186324 D cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation; chemotaxis regulator CheZ 1185680..1186324 Escherichia fergusonii ATCC 35469 7120889 YP_002382308.1 CDS cbpM NC_011740.1 1186370 1186690 R with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA; chaperone-modulator protein CbpM complement(1186370..1186690) Escherichia fergusonii ATCC 35469 7120890 YP_002382309.1 CDS cbpA NC_011740.1 1186675 1187595 R functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock; curved DNA-binding protein CbpA complement(1186675..1187595) Escherichia fergusonii ATCC 35469 7123766 YP_002382310.1 CDS EFER_1148 NC_011740.1 1187798 1188169 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1187798..1188169) Escherichia fergusonii ATCC 35469 7120862 YP_002382311.1 CDS dadA NC_011740.1 1188151 1189404 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; D-amino acid dehydrogenase complement(1188151..1189404) Escherichia fergusonii ATCC 35469 7120268 YP_002382312.1 CDS EFER_1150 NC_011740.1 1189455 1190369 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; LysR family transcriptional regulator complement(1189455..1190369) Escherichia fergusonii ATCC 35469 7124115 YP_002382313.1 CDS EFER_1151 NC_011740.1 1190609 1192075 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 1190609..1192075 Escherichia fergusonii ATCC 35469 7123140 YP_002382314.1 CDS EFER_1152 NC_011740.1 1192067 1192396 R hypothetical protein complement(1192067..1192396) Escherichia fergusonii ATCC 35469 7120329 YP_002382315.1 CDS agp NC_011740.1 1192225 1193466 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12455612, 90368616, 91297199, 2153660, 9298646; Product type e : enzyme; glucose-1-phosphatase/inositol phosphatase 1192225..1193466 Escherichia fergusonii ATCC 35469 7120330 YP_002382316.1 CDS yccJ NC_011740.1 1193560 1193787 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1193560..1193787) Escherichia fergusonii ATCC 35469 7122288 YP_002382317.1 CDS wrbA NC_011740.1 1193808 1194404 R stationary phase protein that binds TrpR repressor; TrpR binding protein WrbA complement(1193808..1194404) Escherichia fergusonii ATCC 35469 7119907 YP_002382318.1 CDS EFER_1157 NC_011740.1 1194797 1194949 D Evidence 6 : Doubtful CDS; hypothetical protein 1194797..1194949 Escherichia fergusonii ATCC 35469 7123683 YP_002382319.1 CDS rutR NC_011740.1 1195157 1195795 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16540542; Product type r : regulator; alternative pyrimidine degradation pathway DNA-binding transcriptional regulator 1195157..1195795 Escherichia fergusonii ATCC 35469 7120331 YP_002382320.1 CDS yliE NC_011740.1 1196881 1199229 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1196881..1199229 Escherichia fergusonii ATCC 35469 7121168 YP_002382321.1 CDS yliF NC_011740.1 1199063 1200574 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 17208514; Product type pe : enzyme; hypothetical protein 1199063..1200574 Escherichia fergusonii ATCC 35469 7123415 YP_002382322.1 CDS bcsA NC_011740.1 1200643 1202748 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11260463, 11929533; Product type e : enzyme; cellulose synthase catalytic subunit 1200643..1202748 Escherichia fergusonii ATCC 35469 7122049 YP_002382323.1 CDS bcsB NC_011740.1 1202813 1204960 D binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); cellulose synthase regulator protein 1202813..1204960 Escherichia fergusonii ATCC 35469 7123357 YP_002382324.1 CDS yedF NC_011740.1 1204998 1205231 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1204998..1205231) Escherichia fergusonii ATCC 35469 7121650 YP_002382325.1 CDS yedE NC_011740.1 1205228 1206433 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; inner membrane protein complement(1205228..1206433) Escherichia fergusonii ATCC 35469 7121539 YP_002382326.1 CDS yedD NC_011740.1 1206620 1207033 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1206620..1207033 Escherichia fergusonii ATCC 35469 7121538 YP_002382327.1 CDS amyA NC_011740.1 1207066 1208553 R converts 1,4-alpha-D-glucans to maltodextrin; alpha-amylase complement(1207066..1208553) Escherichia fergusonii ATCC 35469 7121537 YP_002382328.1 CDS fliT NC_011740.1 1208619 1208990 R binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family; flagellar biosynthesis protein FliT complement(1208619..1208990) Escherichia fergusonii ATCC 35469 7120516 YP_002382329.1 CDS fliS NC_011740.1 1208987 1209397 R flagellin specific chaperone; flagellar protein FliS complement(1208987..1209397) Escherichia fergusonii ATCC 35469 7122996 YP_002382330.1 CDS fliD NC_011740.1 1209416 1210822 R involved in flagellin assembly; flagellar capping protein complement(1209416..1210822) Escherichia fergusonii ATCC 35469 7122995 YP_002382331.1 CDS fliC NC_011740.1 1211032 1212564 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7690024; Product type s : structure; Flagellin 1211032..1212564 Escherichia fergusonii ATCC 35469 7122983 YP_002382332.1 CDS fliA NC_011740.1 1212730 1213446 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes; flagellar biosynthesis sigma factor 1212730..1213446 Escherichia fergusonii ATCC 35469 7122982 YP_002382333.1 CDS fliZ NC_011740.1 1213505 1214044 D expression activator of the class 2 type of flagellar operons, essential to achieve maximal cell motility; activator of type 1 fimbrial gene expression; cell density-responsive regulator; FliZ in Salmonella typhimurium induces HilA, an activator of invasion genes necessary to achieve full virulence; flagella biosynthesis protein FliZ 1213505..1214044 Escherichia fergusonii ATCC 35469 7123564 YP_002382334.1 CDS fliY NC_011740.1 1214132 1214932 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96125225, 8450713, 8774726, 9298646, 9740056; Product type t : transporter; cystine transporter subunit 1214132..1214932 Escherichia fergusonii ATCC 35469 7123567 YP_002382335.1 CDS yedO NC_011740.1 1215039 1216025 D catalyzes the formation of pyruvate from D-cysteine; D-cysteine desulfhydrase 1215039..1216025 Escherichia fergusonii ATCC 35469 7124140 YP_002382336.1 CDS yecS NC_011740.1 1216041 1216709 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter permease 1216041..1216709 Escherichia fergusonii ATCC 35469 7121542 YP_002382337.1 CDS yecC NC_011740.1 1216706 1217458 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; amino-acid ABC transporter ATP-binding protein YecC 1216706..1217458 Escherichia fergusonii ATCC 35469 7123884 YP_002382338.1 CDS sdiA NC_011740.1 1217653 1218408 D regulates genes involved in cell division; DNA-binding transcriptional activator SdiA 1217653..1218408 Escherichia fergusonii ATCC 35469 7121527 YP_002382339.1 CDS yecF NC_011740.1 1218476 1218700 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3515318, 7567469; hypothetical protein complement(1218476..1218700) Escherichia fergusonii ATCC 35469 7121759 YP_002382340.1 CDS uvrY NC_011740.1 1219146 1219802 D in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system; response regulator 1219146..1219802 Escherichia fergusonii ATCC 35469 7123336 YP_002382341.1 CDS uvrC NC_011740.1 1219799 1221631 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 1219799..1221631 Escherichia fergusonii ATCC 35469 7122649 YP_002382342.1 CDS pgsA NC_011740.1 1221688 1222236 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 381294, 7007311, 94253011, 1323047, 3003065, 8917447; Product type e : enzyme; phosphatidylglycerophosphate synthetase 1221688..1222236 Escherichia fergusonii ATCC 35469 7122647 YP_002382343.1 CDS kch NC_011740.1 1222838 1224100 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12912904; Product type t : transporter; voltage-gated potassium channel complement(1222838..1224100) Escherichia fergusonii ATCC 35469 7123631 YP_002382344.1 CDS appC NC_011740.1 1224433 1225977 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92049231, 96198179; Product type c : carrier; cytochrome bd-II oxidase subunit I 1224433..1225977 Escherichia fergusonii ATCC 35469 7120802 YP_002382345.1 CDS appB NC_011740.1 1225989 1227125 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92049231, 96198179; Product type c : carrier; cytochrome bd-II oxidase subunit II 1225989..1227125 Escherichia fergusonii ATCC 35469 7120524 YP_002382346.1 CDS EFER_1187 NC_011740.1 1227396 1227776 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; lipoprotein complement(1227396..1227776) Escherichia fergusonii ATCC 35469 7120523 YP_002382347.1 CDS torS NC_011740.1 1227894 1230638 R Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide; hybrid sensory histidine kinase TorS complement(1227894..1230638) Escherichia fergusonii ATCC 35469 7120332 YP_002382348.1 CDS torT NC_011740.1 1230715 1231743 D periplasmic sensory protein associated with the TorRS two-component regulatory system; TMAO reductase system periplasmic protein TorT 1230715..1231743 Escherichia fergusonii ATCC 35469 7122148 YP_002382349.1 CDS torR NC_011740.1 1231716 1232408 R response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes; DNA-binding transcriptional regulator TorR complement(1231716..1232408) Escherichia fergusonii ATCC 35469 7123987 YP_002382350.1 CDS torC NC_011740.1 1232538 1233710 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94293785, 94314186, 99340208, 11056172, 11562502; Product type c : carrier; trimethylamine N-oxide (TMAO) reductase I, cytochrome c-type subunit 1232538..1233710 Escherichia fergusonii ATCC 35469 7122147 YP_002382351.1 CDS torA NC_011740.1 1233710 1236256 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88193091, 90089471, 94293785, 8302830, 8022286; Product type e : enzyme; trimethylamine N-oxide (TMAO) reductase I, catalytic subunit 1233710..1236256 Escherichia fergusonii ATCC 35469 7122145 YP_002382352.1 CDS torD NC_011740.1 1236220 1236849 D TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; chaperone protein TorD 1236220..1236849 Escherichia fergusonii ATCC 35469 7122144 YP_002382353.1 CDS flhB NC_011740.1 1236998 1238146 D membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 1236998..1238146 Escherichia fergusonii ATCC 35469 7122146 YP_002382354.1 CDS flhA NC_011740.1 1238139 1240217 D membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 1238139..1240217 Escherichia fergusonii ATCC 35469 7122979 YP_002382355.1 CDS flhE NC_011740.1 1240217 1240612 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8002587, 1482109, 89181349; hypothetical protein 1240217..1240612 Escherichia fergusonii ATCC 35469 7122978 YP_002382356.1 CDS argS NC_011740.1 1240810 1242543 R catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase complement(1240810..1242543) Escherichia fergusonii ATCC 35469 7124138 YP_002382357.1 CDS yecM NC_011740.1 1242781 1243347 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12660999; Product type pe : enzyme; hypothetical protein 1242781..1243347 Escherichia fergusonii ATCC 35469 7123179 YP_002382358.1 CDS cutC NC_011740.1 1243353 1244105 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95362641, 7635807; Product type t : transporter; copper homeostasis protein CutC 1243353..1244105 Escherichia fergusonii ATCC 35469 7121533 YP_002382359.1 CDS yecP NC_011740.1 1244186 1245157 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1244186..1245157) Escherichia fergusonii ATCC 35469 7122833 YP_002382360.1 CDS yecO NC_011740.1 1245154 1245897 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11746687; Product type e : enzyme; AdoMet-dependent methyltransferase complement(1245154..1245897) Escherichia fergusonii ATCC 35469 7123337 YP_002382361.1 CDS yecN NC_011740.1 1245938 1246333 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(1245938..1246333) Escherichia fergusonii ATCC 35469 7121535 YP_002382362.1 CDS yecE NC_011740.1 1246386 1247204 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2129559, 7984428; hypothetical protein complement(1246386..1247204) Escherichia fergusonii ATCC 35469 7121534 YP_002382363.1 CDS yecD NC_011740.1 1247201 1247767 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein complement(1247201..1247767) Escherichia fergusonii ATCC 35469 7121529 YP_002382364.1 CDS aspS NC_011740.1 1248077 1249849 D catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 1248077..1249849 Escherichia fergusonii ATCC 35469 7121528 YP_002382365.1 CDS ntpA NC_011740.1 1249851 1250294 D converts dATP to dAMP and pyrophosphate; dATP pyrophosphohydrolase 1249851..1250294 Escherichia fergusonii ATCC 35469 7123183 YP_002382366.1 CDS yebC NC_011740.1 1250323 1251063 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1250323..1251063 Escherichia fergusonii ATCC 35469 7119667 YP_002382367.1 CDS ruvC NC_011740.1 1251097 1251618 D endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 1251097..1251618 Escherichia fergusonii ATCC 35469 7121515 YP_002382368.1 CDS yebB NC_011740.1 1251620 1252222 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1251620..1252222) Escherichia fergusonii ATCC 35469 7121170 YP_002382369.1 CDS ruvA NC_011740.1 1252497 1253108 D plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 1252497..1253108 Escherichia fergusonii ATCC 35469 7123333 YP_002382370.1 CDS ruvB NC_011740.1 1253117 1254127 D promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1253117..1254127 Escherichia fergusonii ATCC 35469 7123278 YP_002382371.1 CDS znuB NC_011740.1 1254273 1255058 R involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter membrane protein complement(1254273..1255058) Escherichia fergusonii ATCC 35469 7121169 YP_002382372.1 CDS znuC NC_011740.1 1255051 1255809 R involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter ATPase complement(1255051..1255809) Escherichia fergusonii ATCC 35469 7119776 YP_002382373.1 CDS znuA NC_011740.1 1255834 1256820 D involved in transport of zinc(II) with ZnuA and C; high-affinity zinc transporter periplasmic protein 1255834..1256820 Escherichia fergusonii ATCC 35469 7122666 YP_002382374.1 CDS yebA NC_011740.1 1256836 1258158 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1732206; Product type pe : enzyme; hypothetical protein 1256836..1258158 Escherichia fergusonii ATCC 35469 7119775 YP_002382375.1 CDS lpxM NC_011740.1 1258279 1259250 D Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase 1258279..1259250 Escherichia fergusonii ATCC 35469 7121514 YP_002382376.1 CDS pykA NC_011740.1 1259402 1260844 R catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase complement(1259402..1260844) Escherichia fergusonii ATCC 35469 7121204 YP_002382377.1 CDS yebK NC_011740.1 1260966 1261835 R Represses the expression of the zwf, eda, glp and gap; DNA-binding transcriptional regulator HexR complement(1260966..1261835) Escherichia fergusonii ATCC 35469 7122332 YP_002382378.1 CDS zwf NC_011740.1 1262165 1263640 D catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 1262165..1263640 Escherichia fergusonii ATCC 35469 7121519 YP_002382379.1 CDS edd NC_011740.1 1263863 1265674 D catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate; phosphogluconate dehydratase 1263863..1265674 Escherichia fergusonii ATCC 35469 7122061 YP_002382380.1 CDS eda NC_011740.1 1265711 1266352 D catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase 1265711..1266352 Escherichia fergusonii ATCC 35469 7124131 YP_002382381.1 CDS purT NC_011740.1 1266517 1267695 R non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 complement(1266517..1267695) Escherichia fergusonii ATCC 35469 7122937 YP_002382382.1 CDS yebG NC_011740.1 1267679 1268116 D Evidence 2b : Function of strongly homologous gene; Product type ph : phenotype; DNA damage-inducible protein 1267679..1268116 Escherichia fergusonii ATCC 35469 7122328 YP_002382383.1 CDS yebF NC_011740.1 1268171 1268539 D secreted protein; unknown function; hypothetical protein 1268171..1268539 Escherichia fergusonii ATCC 35469 7121518 YP_002382384.1 CDS yebE NC_011740.1 1268750 1269415 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1268750..1269415 Escherichia fergusonii ATCC 35469 7121517 YP_002382385.1 CDS ptrB NC_011740.1 1269504 1271579 D PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues; protease 2 1269504..1271579 Escherichia fergusonii ATCC 35469 7121516 YP_002382386.1 CDS exoX NC_011740.1 1271561 1272223 R 3'-5' exonuclease activity on single or double-strand DNA; exodeoxyribonuclease X complement(1271561..1272223) Escherichia fergusonii ATCC 35469 7122313 YP_002382387.1 CDS EFER_1230 NC_011740.1 1272247 1272936 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1272247..1272936) Escherichia fergusonii ATCC 35469 7119976 YP_002382388.1 CDS EFER_1231 NC_011740.1 1273011 1273328 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; DNA polymerase III subunit theta complement(1273011..1273328) Escherichia fergusonii ATCC 35469 7120333 YP_002382389.1 CDS EFER_1232 NC_011740.1 1273380 1273754 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1273380..1273754 Escherichia fergusonii ATCC 35469 7120334 YP_002382390.1 CDS yebZ NC_011740.1 1273757 1274629 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; copper ion transport inner membrane protein YebZ 1273757..1274629 Escherichia fergusonii ATCC 35469 7120335 YP_002382391.1 CDS yebY NC_011740.1 1274641 1274982 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1274641..1274982 Escherichia fergusonii ATCC 35469 7121526 YP_002382392.1 CDS EFER_1235 NC_011740.1 1275000 1275152 D Evidence 6 : Doubtful CDS; hypothetical protein 1275000..1275152 Escherichia fergusonii ATCC 35469 7123335 YP_002382393.1 CDS pphA NC_011740.1 1275377 1276033 D Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins; serine/threonine protein phosphatase 1 1275377..1276033 Escherichia fergusonii ATCC 35469 7123819 YP_002382394.1 CDS yebW NC_011740.1 1276034 1276309 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1276034..1276309) Escherichia fergusonii ATCC 35469 7120111 YP_002382395.1 CDS yebV NC_011740.1 1276330 1276566 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1276330..1276566) Escherichia fergusonii ATCC 35469 7123882 YP_002382396.1 CDS yebU NC_011740.1 1276685 1278124 R in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA; rRNA (cytosine-C(5)-)-methyltransferase RsmF complement(1276685..1278124) Escherichia fergusonii ATCC 35469 7121525 YP_002382397.1 CDS yebT NC_011740.1 1278204 1280837 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1278204..1280837) Escherichia fergusonii ATCC 35469 7121524 YP_002382398.1 CDS yebS NC_011740.1 1280806 1282089 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(1280806..1282089) Escherichia fergusonii ATCC 35469 7121523 YP_002382399.1 CDS yebR NC_011740.1 1282165 1282716 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1282165..1282716 Escherichia fergusonii ATCC 35469 7121522 YP_002382400.1 CDS proQ NC_011740.1 1282813 1283502 D affects solute and DNA transport through an unknown mechanism; solute/DNA competence effector 1282813..1283502 Escherichia fergusonii ATCC 35469 7123334 YP_002382401.1 CDS prc NC_011740.1 1283522 1285570 D Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3; carboxy-terminal protease 1283522..1285570 Escherichia fergusonii ATCC 35469 7123649 YP_002382402.1 CDS htpX NC_011740.1 1285751 1286632 D metalloprotease; heat shock protein HtpX 1285751..1286632 Escherichia fergusonii ATCC 35469 7120122 YP_002382403.1 CDS yebQ NC_011740.1 1286680 1288053 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; MFS superfamily transporter complement(1286680..1288053) Escherichia fergusonii ATCC 35469 7122232 YP_002382404.1 CDS kdgR NC_011740.1 1288229 1289011 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15659677, 4359651; Product type r : regulator; DNA-binding transcriptional repressor KdgR 1288229..1289011 Escherichia fergusonii ATCC 35469 7121521 YP_002382405.1 CDS EFER_1248 NC_011740.1 1289345 1289464 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1289345..1289464) Escherichia fergusonii ATCC 35469 7120804 YP_002382406.1 CDS yobG NC_011740.1 1289603 1289758 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1289603..1289758 Escherichia fergusonii ATCC 35469 7120337 YP_002382407.1 CDS EFER_1250 NC_011740.1 1289832 1290119 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1289832..1290119 Escherichia fergusonii ATCC 35469 7121728 YP_002382408.1 CDS yobF NC_011740.1 1290945 1291088 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1290945..1291088 Escherichia fergusonii ATCC 35469 7120338 YP_002382409.1 CDS cspC NC_011740.1 1291101 1291310 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20345064, 21101802, 94293754, 12071744, 7984109, 8022261, 9298646, 9868784, 9921691; Product type f : factor; cold shock-like protein CspC 1291101..1291310 Escherichia fergusonii ATCC 35469 7121727 YP_002382410.1 CDS rrmA NC_011740.1 1291467 1292276 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9440525; Product type e : enzyme; Ribosomal RNA large subunit methyltransferase A (rRNA (guanine-N(1)-)-methyltransferase) (23S rRNA m1G745 methyltransferase) 1291467..1292276 Escherichia fergusonii ATCC 35469 7122819 YP_002382411.1 CDS yebN NC_011740.1 1292273 1292839 R membrane protein YebN; hypothetical protein complement(1292273..1292839) Escherichia fergusonii ATCC 35469 7121142 YP_002382412.1 CDS EFER_1255 NC_011740.1 1292836 1293081 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1292836..1293081) Escherichia fergusonii ATCC 35469 7121520 YP_002382413.1 CDS yobD NC_011740.1 1293268 1293726 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(1293268..1293726) Escherichia fergusonii ATCC 35469 7120339 YP_002382414.1 CDS manZ NC_011740.1 1293781 1294641 R hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; PTS system mannose-specific transporter subunit IID complement(1293781..1294641) Escherichia fergusonii ATCC 35469 7121726 YP_002382415.1 CDS manY NC_011740.1 1294645 1295445 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10473571, 87165962, 90036983, 94086520, 97128775, 7811395, 8774730; Product type t : transporter; mannose-specific PTS system transporter subunit IIC complement(1294645..1295445) Escherichia fergusonii ATCC 35469 7123832 YP_002382416.1 CDS manX NC_011740.1 1295507 1296478 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87165962, 90036983, 8131846, 8676384, 9074635, 9298646; Product type t : transporter; PTS system mannose-specific transporter subunit IIAB complement(1295507..1296478) Escherichia fergusonii ATCC 35469 7123289 YP_002382417.1 CDS yoaE NC_011740.1 1296912 1298498 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; membrane protein 1296912..1298498 Escherichia fergusonii ATCC 35469 7121230 YP_002382418.1 CDS adrB NC_011740.1 1298501 1300108 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16513732; Product type pe : enzyme; cyclic di-GMP phosphodiesterase complement(1298501..1300108) Escherichia fergusonii ATCC 35469 7121723 YP_002382419.1 CDS sdaA NC_011740.1 1300230 1301594 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15155761, 89359152, 91056090, 93170282; Product type e : enzyme; L-serine deaminase I complement(1300230..1301594) Escherichia fergusonii ATCC 35469 7122278 YP_002382420.1 CDS yeaB NC_011740.1 1301778 1302356 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7567469; Product type pe : enzyme; hypothetical protein complement(1301778..1302356) Escherichia fergusonii ATCC 35469 7123919 YP_002382421.1 CDS pabB NC_011740.1 1302359 1303720 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88025006, 91067712, 91302313, 96011382, 6330050, 7896119; Product type e : enzyme; aminodeoxychorismate synthase subunit I complement(1302359..1303720) Escherichia fergusonii ATCC 35469 7122728 YP_002382422.1 CDS yoaH NC_011740.1 1303794 1303973 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1303794..1303973 Escherichia fergusonii ATCC 35469 7122550 YP_002382423.1 CDS EFER_1266 NC_011740.1 1304144 1304389 D Evidence 6 : Doubtful CDS; hypothetical protein 1304144..1304389 Escherichia fergusonii ATCC 35469 7121725 YP_002382424.1 CDS EFER_1267 NC_011740.1 1304471 1305370 D Evidence 6 : Doubtful CDS; hypothetical protein 1304471..1305370 Escherichia fergusonii ATCC 35469 7120340 YP_002382425.1 CDS yoaC NC_011740.1 1305526 1305915 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1305526..1305915) Escherichia fergusonii ATCC 35469 7123141 YP_002382426.1 CDS yoaB NC_011740.1 1306087 1306431 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1306087..1306431) Escherichia fergusonii ATCC 35469 7123913 YP_002382427.1 CDS EFER_1270 NC_011740.1 1306684 1306896 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1306684..1306896) Escherichia fergusonii ATCC 35469 7121722 YP_002382428.1 CDS EFER_1271 NC_011740.1 1306893 1307105 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1306893..1307105) Escherichia fergusonii ATCC 35469 7120341 YP_002382429.1 CDS yoaA NC_011740.1 1307402 1309312 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; ATP-dependent helicase 1307402..1309312 Escherichia fergusonii ATCC 35469 7123684 YP_002382430.1 CDS yeaZ NC_011740.1 1309370 1310065 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; peptidase 1309370..1310065 Escherichia fergusonii ATCC 35469 7123367 YP_002382431.1 CDS yeaY NC_011740.1 1310104 1310685 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16079137; Product type lp : lipoprotein; outer membrane-associated lipoprotein 1310104..1310685 Escherichia fergusonii ATCC 35469 7121513 YP_002382432.1 CDS fadD NC_011740.1 1310890 1312575 D Activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 1310890..1312575 Escherichia fergusonii ATCC 35469 7123332 YP_002382433.1 CDS rnd NC_011740.1 1312643 1313770 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88289400, 89053950, 93015723, 8107670; Product type e : enzyme; ribonuclease D 1312643..1313770 Escherichia fergusonii ATCC 35469 7119987 YP_002382434.1 CDS ycfS NC_011740.1 1313809 1314789 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1313809..1314789) Escherichia fergusonii ATCC 35469 7121424 YP_002382435.1 CDS mfd NC_011740.1 1314930 1318376 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14602898, 90158497, 92107993, 8465200; Product type f : factor; transcription-repair coupling factor complement(1314930..1318376) Escherichia fergusonii ATCC 35469 7123614 YP_002382436.1 CDS ycfT NC_011740.1 1318504 1319577 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(1318504..1319577) Escherichia fergusonii ATCC 35469 7120927 YP_002382437.1 CDS lolC NC_011740.1 1319839 1321038 D part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolC 1319839..1321038 Escherichia fergusonii ATCC 35469 7119928 YP_002382438.1 CDS lolD NC_011740.1 1321031 1321732 D outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone; lipoprotein transporter ATP-binding subunit 1321031..1321732 Escherichia fergusonii ATCC 35469 7120845 YP_002382439.1 CDS lolE NC_011740.1 1321732 1322976 D part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; outer membrane-specific lipoprotein transporter subunit LolE 1321732..1322976 Escherichia fergusonii ATCC 35469 7120846 YP_002382440.1 CDS ycfX NC_011740.1 1323005 1323916 D catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine; N-acetyl-D-glucosamine kinase 1323005..1323916 Escherichia fergusonii ATCC 35469 7120847 YP_002382441.1 CDS cobB NC_011740.1 1323932 1324753 D Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent deacetylase 1323932..1324753 Escherichia fergusonii ATCC 35469 7119929 YP_002382442.1 CDS ycfZ NC_011740.1 1324890 1325675 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(1324890..1325675) Escherichia fergusonii ATCC 35469 7120911 YP_002382443.1 CDS ymfA NC_011740.1 1325672 1326133 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(1325672..1326133) Escherichia fergusonii ATCC 35469 7123615 YP_002382444.1 CDS potD NC_011740.1 1326191 1327237 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate; spermidine/putrescine ABC transporter substrate-binding protein complement(1326191..1327237) Escherichia fergusonii ATCC 35469 7123418 YP_002382445.1 CDS potC NC_011740.1 1327234 1328028 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component; spermidine/putrescine ABC transporter membrane protein complement(1327234..1328028) Escherichia fergusonii ATCC 35469 7120101 YP_002382446.1 CDS potB NC_011740.1 1328025 1328852 R can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component; spermidine/putrescine ABC transporter membrane protein complement(1328025..1328852) Escherichia fergusonii ATCC 35469 7123644 YP_002382447.1 CDS potA NC_011740.1 1328866 1330002 R functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase; putrescine/spermidine ABC transporter ATPase complement(1328866..1330002) Escherichia fergusonii ATCC 35469 7120100 YP_002382448.1 CDS pepT NC_011740.1 1330251 1331477 D catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 1330251..1331477 Escherichia fergusonii ATCC 35469 7120099 YP_002382449.1 CDS yeaD NC_011740.1 1331528 1332472 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1331528..1332472) Escherichia fergusonii ATCC 35469 7122579 YP_002382450.1 CDS gapA NC_011740.1 1332487 1333482 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 775311, 94131963, 98361923, 1862091, 2124629, 2990926, 7896119, 8636984, 9298646; Product type e : enzyme; glyceraldehyde-3-phosphate dehydrogenase complement(1332487..1333482) Escherichia fergusonii ATCC 35469 7123525 YP_002382451.1 CDS msrB NC_011740.1 1333825 1334238 D this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 1333825..1334238 Escherichia fergusonii ATCC 35469 7120173 YP_002382452.1 CDS yeaC NC_011740.1 1334235 1334558 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1334235..1334558 Escherichia fergusonii ATCC 35469 7120974 YP_002382453.1 CDS pncA NC_011740.1 1334620 1335297 R catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide; nicotinamidase/pyrazinamidase complement(1334620..1335297) Escherichia fergusonii ATCC 35469 7124094 YP_002382454.1 CDS ansA NC_011740.1 1335272 1336288 R converts asparagine to aspartate and ammonia; asparaginase complement(1335272..1336288) Escherichia fergusonii ATCC 35469 7123102 YP_002382455.1 CDS EFER_1298 NC_011740.1 1336404 1337114 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1336404..1337114) Escherichia fergusonii ATCC 35469 7120518 YP_002382456.1 CDS sppA NC_011740.1 1337250 1339385 R SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane; protease 4 complement(1337250..1339385) Escherichia fergusonii ATCC 35469 7123685 YP_002382457.1 CDS ydjA NC_011740.1 1339267 1339818 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 1339267..1339818 Escherichia fergusonii ATCC 35469 7123380 YP_002382458.1 CDS selD NC_011740.1 1339935 1340978 D catalyzes the formation of selenophosphate from selenide and ATP; selenophosphate synthetase 1339935..1340978 Escherichia fergusonii ATCC 35469 7122722 YP_002382459.1 CDS topB NC_011740.1 1340956 1342938 D decatenates replicating daughter chromosomes; DNA topoisomerase III 1340956..1342938 Escherichia fergusonii ATCC 35469 7123374 YP_002382460.1 CDS ynjI NC_011740.1 1343066 1344106 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1343066..1344106 Escherichia fergusonii ATCC 35469 7122143 YP_002382461.1 CDS gdhA NC_011740.1 1344223 1345566 R converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase complement(1344223..1345566) Escherichia fergusonii ATCC 35469 7121721 YP_002382462.1 CDS EFER_1305 NC_011740.1 1345917 1346192 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1345917..1346192 Escherichia fergusonii ATCC 35469 7123657 YP_002382463.1 CDS nudG NC_011740.1 1346152 1346565 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21101911; Product type e : enzyme; pyrimidine (deoxy)nucleoside triphosphate pyrophosphohydrolase complement(1346152..1346565) Escherichia fergusonii ATCC 35469 7120342 YP_002382464.1 CDS EFER_1307 NC_011740.1 1346677 1346829 R hypothetical protein complement(1346677..1346829) Escherichia fergusonii ATCC 35469 7119672 YP_002382465.1 CDS ynjF NC_011740.1 1346805 1347425 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type m : membrane component; phosphatidyl transferase, inner membrane protein 1346805..1347425 Escherichia fergusonii ATCC 35469 7120343 YP_002382466.1 CDS ynjE NC_011740.1 1347434 1348741 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; thiosulfate sulfur transferase / thiosulfate binding protein complement(1347434..1348741) Escherichia fergusonii ATCC 35469 7121720 YP_002382467.1 CDS ynjD NC_011740.1 1348808 1349461 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; sulfate/thiosulfate ABC transporter ATP-binding protein complement(1348808..1349461) Escherichia fergusonii ATCC 35469 7123366 YP_002382468.1 CDS ynjC NC_011740.1 1349461 1350951 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter membrane protein complement(1349461..1350951) Escherichia fergusonii ATCC 35469 7121719 YP_002382469.1 CDS ynjB NC_011740.1 1350969 1352135 R Evidence 4 : Homologs of previously reported genes of unknown function; ABC transporter substrate-binding protein complement(1350969..1352135) Escherichia fergusonii ATCC 35469 7121718 YP_002382470.1 CDS ynjA NC_011740.1 1352145 1352693 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1352145..1352693) Escherichia fergusonii ATCC 35469 7121717 YP_002382471.1 CDS ydjZ NC_011740.1 1352693 1353397 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(1352693..1353397) Escherichia fergusonii ATCC 35469 7121716 YP_002382472.1 CDS ydjX NC_011740.1 1353401 1354105 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1353401..1354105) Escherichia fergusonii ATCC 35469 7122727 YP_002382473.1 CDS xthA NC_011740.1 1354262 1355068 R removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction; exonuclease III complement(1354262..1355068) Escherichia fergusonii ATCC 35469 7122726 YP_002382474.1 CDS astC NC_011740.1 1355514 1356734 D catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate; bifunctional succinylornithine transaminase/acetylornithine transaminase 1355514..1356734 Escherichia fergusonii ATCC 35469 7122387 YP_002382475.1 CDS astA NC_011740.1 1356731 1357765 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14675764, 98361920; Product type e : enzyme; arginine succinyltransferase 1356731..1357765 Escherichia fergusonii ATCC 35469 7123610 YP_002382476.1 CDS astD NC_011740.1 1357762 1359240 D a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH; succinylglutamic semialdehyde dehydrogenase 1357762..1359240 Escherichia fergusonii ATCC 35469 7120574 YP_002382477.1 CDS astB NC_011740.1 1359237 1360580 D catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation; succinylarginine dihydrolase 1359237..1360580 Escherichia fergusonii ATCC 35469 7121626 YP_002382478.1 CDS astE NC_011740.1 1360573 1361541 D catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism; succinylglutamate desuccinylase 1360573..1361541 Escherichia fergusonii ATCC 35469 7120575 YP_002382479.1 CDS spy NC_011740.1 1361871 1362356 D periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP; hypothetical protein 1361871..1362356 Escherichia fergusonii ATCC 35469 7123352 YP_002382480.1 CDS ydjR NC_011740.1 1362549 1363139 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 21862596; hypothetical protein 1362549..1363139 Escherichia fergusonii ATCC 35469 7121812 YP_002382481.1 CDS ydjQ NC_011740.1 1363099 1363986 R 3' incision activity; acts with UvrC; nucleotide excision repair endonuclease complement(1363099..1363986) Escherichia fergusonii ATCC 35469 7122725 YP_002382482.1 CDS nadE NC_011740.1 1364253 1365080 R catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase complement(1364253..1365080) Escherichia fergusonii ATCC 35469 7123524 YP_002382483.1 CDS osmE NC_011740.1 1365282 1365620 D osmotically-inducible lipoprotein E; activator of ntr-like gene protein; DNA-binding transcriptional activator OsmE 1365282..1365620 Escherichia fergusonii ATCC 35469 7120661 YP_002382484.1 CDS chbB NC_011740.1 1365917 1366237 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIB 1365917..1366237 Escherichia fergusonii ATCC 35469 7123035 YP_002382485.1 CDS chbC NC_011740.1 1366322 1367680 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC 1366322..1367680 Escherichia fergusonii ATCC 35469 7120881 YP_002382486.1 CDS chbA NC_011740.1 1367733 1368083 D catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system N,N'-diacetylchitobiose-specific transporter subunit IIA 1367733..1368083 Escherichia fergusonii ATCC 35469 7120882 YP_002382487.1 CDS chbR NC_011740.1 1368091 1368933 D represses the celABCDF-ydjC operon involved in carbon uptake; DNA-binding transcriptional regulator ChbR 1368091..1368933 Escherichia fergusonii ATCC 35469 7120880 YP_002382488.1 CDS chbF NC_011740.1 1369054 1370406 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20042356, 90185127, 9405618; Product type e : enzyme; cryptic phospho-beta-glucosidase 1369054..1370406 Escherichia fergusonii ATCC 35469 7120885 YP_002382489.1 CDS chbG NC_011740.1 1370419 1371177 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 20042356, 1987146, 2179047, 8121401, 9405618; hypothetical protein 1370419..1371177 Escherichia fergusonii ATCC 35469 7120883 YP_002382490.1 CDS katE NC_011740.1 1371224 1373485 R Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; hydroperoxidase II complement(1371224..1373485) Escherichia fergusonii ATCC 35469 7120884 YP_002382491.1 CDS EFER_1336 NC_011740.1 1373581 1373730 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1373581..1373730 Escherichia fergusonii ATCC 35469 7120799 YP_002382492.1 CDS cedA NC_011740.1 1373669 1373932 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9427399; Product type cp : cell process; cell division modulator 1373669..1373932 Escherichia fergusonii ATCC 35469 7123686 YP_002382493.1 CDS ydjN NC_011740.1 1373979 1375370 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; cation-acid symporter complement(1373979..1375370) Escherichia fergusonii ATCC 35469 7120877 YP_002382494.1 CDS ydjM NC_011740.1 1375502 1376092 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10760155; Product type pm : membrane component; hypothetical protein complement(1375502..1376092) Escherichia fergusonii ATCC 35469 7122724 YP_002382495.1 CDS yniC NC_011740.1 1376251 1376919 R YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate; 2-deoxyglucose-6-phosphatase complement(1376251..1376919) Escherichia fergusonii ATCC 35469 7122723 YP_002382496.1 CDS yniB NC_011740.1 1377068 1377604 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1377068..1377604 Escherichia fergusonii ATCC 35469 7121715 YP_002382497.1 CDS yniA NC_011740.1 1377653 1378513 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; phosphotransferase/kinase complement(1377653..1378513) Escherichia fergusonii ATCC 35469 7121714 YP_002382498.1 CDS EFER_1343 NC_011740.1 1378623 1378934 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1378623..1378934) Escherichia fergusonii ATCC 35469 7123365 YP_002382499.1 CDS pfkB NC_011740.1 1379001 1379933 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 78194149, 88292964, 6235149, 6310120; Product type e : enzyme; 6-phosphofructokinase complement(1379001..1379933) Escherichia fergusonii ATCC 35469 7123142 YP_002382500.1 CDS ydiY NC_011740.1 1380221 1380979 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1380221..1380979 Escherichia fergusonii ATCC 35469 7122582 YP_002382501.1 CDS thrS NC_011740.1 1381471 1383399 D catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; threonyl-tRNA synthetase 1381471..1383399 Escherichia fergusonii ATCC 35469 7122721 YP_002382502.1 CDS rpmI NC_011740.1 1384042 1384239 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93085722, 10094780, 3298224, 3542048, 6325158; Product type s : structure; 50S ribosomal protein L35 1384042..1384239 Escherichia fergusonii ATCC 35469 7120739 YP_002382503.1 CDS rplT NC_011740.1 1384292 1384648 D binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 1384292..1384648 Escherichia fergusonii ATCC 35469 7121118 YP_002382505.1 CDS pheS NC_011740.1 1385099 1386082 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 1385099..1386082 Escherichia fergusonii ATCC 35469 7122593 YP_002382506.1 CDS pheT NC_011740.1 1386097 1388484 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 1386097..1388484 Escherichia fergusonii ATCC 35469 7122595 YP_002382507.1 CDS ihfA NC_011740.1 1388489 1388788 D This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 1388489..1388788 Escherichia fergusonii ATCC 35469 7123505 YP_002382508.1 CDS btuC NC_011740.1 1388889 1389869 D with BtuD and BtuF transports vitamin B12 into the cell; vtamin B12-transporter permease 1388889..1389869 Escherichia fergusonii ATCC 35469 7120724 YP_002382509.1 CDS btuD NC_011740.1 1389873 1390622 D ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell; vitamin B12-transporter ATPase 1389873..1390622 Escherichia fergusonii ATCC 35469 7123907 YP_002382510.1 CDS nlpC NC_011740.1 1390700 1391164 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12620121; Product type lp : lipoprotein; peptidase lipoprotein 1390700..1391164 Escherichia fergusonii ATCC 35469 7121681 YP_002382511.1 CDS EFER_1357 NC_011740.1 1391365 1392120 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1391365..1392120 Escherichia fergusonii ATCC 35469 7120698 YP_002382512.1 CDS ydiU NC_011740.1 1392186 1393628 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1392186..1393628 Escherichia fergusonii ATCC 35469 7120344 YP_002382513.1 CDS EFER_1359 NC_011740.1 1393630 1393827 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1393630..1393827) Escherichia fergusonii ATCC 35469 7122720 YP_002382514.1 CDS aroH NC_011740.1 1393954 1395000 R tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate; phospho-2-dehydro-3-deoxyheptonate aldolase complement(1393954..1395000) Escherichia fergusonii ATCC 35469 7123687 YP_002382515.1 CDS ydiA NC_011740.1 1395283 1396116 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1395283..1396116) Escherichia fergusonii ATCC 35469 7120550 YP_002382516.1 CDS pps NC_011740.1 1396452 1398830 D catalyzes the formation of phosphoenolpyruvate from pyruvate; phosphoenolpyruvate synthase 1396452..1398830 Escherichia fergusonii ATCC 35469 7122716 YP_002382517.1 CDS EFER_1363 NC_011740.1 1398901 1399404 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1398901..1399404) Escherichia fergusonii ATCC 35469 7120117 YP_002382518.1 CDS ydiK NC_011740.1 1399647 1400759 R YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function; inner membrane protein complement(1399647..1400759) Escherichia fergusonii ATCC 35469 7121125 YP_002382519.1 CDS ydiJ NC_011740.1 1401028 1404084 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11102686; Product type pe : enzyme; hypothetical protein 1401028..1404084 Escherichia fergusonii ATCC 35469 7122719 YP_002382520.1 CDS ydiI NC_011740.1 1404081 1404491 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15808744; Product type pe : enzyme; esterase 1404081..1404491 Escherichia fergusonii ATCC 35469 7122718 YP_002382521.1 CDS sufA NC_011740.1 1405132 1405500 D functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein; iron-sulfur cluster assembly scaffold protein 1405132..1405500 Escherichia fergusonii ATCC 35469 7124093 YP_002382522.1 CDS sufB NC_011740.1 1405509 1406996 D with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB 1405509..1406996 Escherichia fergusonii ATCC 35469 7121959 YP_002382523.1 CDS sufC NC_011740.1 1407006 1407752 D part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; cysteine desulfurase ATPase 1407006..1407752 Escherichia fergusonii ATCC 35469 7121960 YP_002382524.1 CDS sufD NC_011740.1 1407727 1408998 D with SufBC activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufD 1407727..1408998 Escherichia fergusonii ATCC 35469 7121961 YP_002382525.1 CDS sufS NC_011740.1 1408995 1410215 D catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine; bifunctional cysteine desulfurase/selenocysteine lyase 1408995..1410215 Escherichia fergusonii ATCC 35469 7121962 YP_002382526.1 CDS sufE NC_011740.1 1410228 1410644 D Acts with SufS to catalyze the formation of L-alanine from L-cysteine; cysteine desufuration protein SufE 1410228..1410644 Escherichia fergusonii ATCC 35469 7123954 YP_002382527.1 CDS ynhG NC_011740.1 1410793 1411794 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1410793..1411794 Escherichia fergusonii ATCC 35469 7121963 YP_002382528.1 CDS lpp NC_011740.1 1411848 1412084 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 334727, 338599, 322142, 353292, 391404, 4261992, 4575979, 6765942; Product type lp : lipoprotein; murein lipoprotein complement(1411848..1412084) Escherichia fergusonii ATCC 35469 7121713 YP_002382529.1 CDS pykF NC_011740.1 1412393 1413805 R catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase complement(1412393..1413805) Escherichia fergusonii ATCC 35469 7120851 YP_002382530.1 CDS ydhZ NC_011740.1 1414319 1414528 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1414319..1414528 Escherichia fergusonii ATCC 35469 7124023 YP_002382531.1 CDS ydhS NC_011740.1 1414567 1416177 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein complement(1414567..1416177) Escherichia fergusonii ATCC 35469 7122715 YP_002382532.1 CDS ydhR NC_011740.1 1416338 1416643 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1416338..1416643) Escherichia fergusonii ATCC 35469 7122714 YP_002382533.1 CDS mdtK NC_011740.1 1417061 1418434 R NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug efflux protein complement(1417061..1418434) Escherichia fergusonii ATCC 35469 7120079 YP_002382534.1 CDS ribC NC_011740.1 1418652 1419299 D catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 1418652..1419299 Escherichia fergusonii ATCC 35469 7121254 YP_002382535.1 CDS cfa NC_011740.1 1419340 1420488 R catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge; cyclopropane-fatty-acyl-phospholipid synthase complement(1419340..1420488) Escherichia fergusonii ATCC 35469 7121406 YP_002382536.1 CDS ydhC NC_011740.1 1420778 1421983 R uncharacterized member of the major facilitator superfamily (MFS); inner membrane transport protein YdhC complement(1420778..1421983) Escherichia fergusonii ATCC 35469 7120878 YP_002382537.1 CDS ydhB NC_011740.1 1422097 1423029 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2404765; Product type pr : regulator; DNA-binding transcriptional regulator 1422097..1423029 Escherichia fergusonii ATCC 35469 7123521 YP_002382538.1 CDS purR NC_011740.1 1423026 1424051 R binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers; DNA-binding transcriptional repressor PurR complement(1423026..1424051) Escherichia fergusonii ATCC 35469 7122708 YP_002382539.1 CDS ydhP NC_011740.1 1424605 1425771 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; efflux protein 1424605..1425771 Escherichia fergusonii ATCC 35469 7122327 YP_002382540.1 CDS sodB NC_011740.1 1425817 1426398 R SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals; superoxide dismutase complement(1425817..1426398) Escherichia fergusonii ATCC 35469 7123523 YP_002382541.1 CDS EFER_1389 NC_011740.1 1426604 1427443 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1426604..1427443) Escherichia fergusonii ATCC 35469 7121797 YP_002382542.1 CDS ydhD NC_011740.1 1427770 1428114 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15833738, 15840565, 11950925, 12730244; Product type e : enzyme; hypothetical protein 1427770..1428114 Escherichia fergusonii ATCC 35469 7120346 YP_002382543.1 CDS lhr NC_011740.1 1428207 1432829 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; ATP-dependent helicase lhr complement(1428207..1432829) Escherichia fergusonii ATCC 35469 7122709 YP_002382544.1 CDS rnt NC_011740.1 1432917 1433564 R Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T complement(1432917..1433564) Escherichia fergusonii ATCC 35469 7120831 YP_002382545.1 CDS gloA NC_011740.1 1433667 1434074 R Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione; glyoxalase I complement(1433667..1434074) Escherichia fergusonii ATCC 35469 7123318 YP_002382546.1 CDS nemA NC_011740.1 1434155 1435252 R FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide; N-ethylmaleimide reductase complement(1434155..1435252) Escherichia fergusonii ATCC 35469 7123660 YP_002382547.1 CDS ydhM NC_011740.1 1435289 1435804 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator complement(1435289..1435804) Escherichia fergusonii ATCC 35469 7120684 YP_002382548.1 CDS ydhF NC_011740.1 1436279 1437175 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; oxidoreductase 1436279..1437175 Escherichia fergusonii ATCC 35469 7124092 YP_002382549.1 CDS sodC NC_011740.1 1437256 1437777 D SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water; superoxide dismutase 1437256..1437777 Escherichia fergusonii ATCC 35469 7122710 YP_002382550.1 CDS ydhK NC_011740.1 1437778 1439787 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(1437778..1439787) Escherichia fergusonii ATCC 35469 7121798 YP_002382551.1 CDS ydhJ NC_011740.1 1439788 1440654 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12900028; Product type e : enzyme; undecaprenyl pyrophosphate phosphatase complement(1439788..1440654) Escherichia fergusonii ATCC 35469 7122712 YP_002382552.1 CDS ydhI NC_011740.1 1440648 1440884 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1440648..1440884) Escherichia fergusonii ATCC 35469 7123522 YP_002382553.1 CDS slyA NC_011740.1 1441082 1441522 D Transcription regulator that can both activate or repress expression; transcriptional regulator SlyA 1441082..1441522 Escherichia fergusonii ATCC 35469 7122711 YP_002382554.1 CDS slyB NC_011740.1 1441568 1442035 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8544813; Product type lp : lipoprotein; outer membrane lipoprotein complement(1441568..1442035) Escherichia fergusonii ATCC 35469 7121790 YP_002382555.1 CDS anmK NC_011740.1 1442309 1443433 D catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 1442309..1443433 Escherichia fergusonii ATCC 35469 7121791 YP_002382556.1 CDS ydhA NC_011740.1 1443471 1443848 D MliC; membrane-bound lysozyme inhibitor of c-type lysozyme; lysozyme inhibitor 1443471..1443848 Escherichia fergusonii ATCC 35469 7120517 YP_002382557.1 CDS pdxH NC_011740.1 1443906 1444562 D catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase 1443906..1444562 Escherichia fergusonii ATCC 35469 7122707 YP_002382558.1 CDS tyrS NC_011740.1 1444689 1445963 D catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 1444689..1445963 Escherichia fergusonii ATCC 35469 7124063 YP_002382559.1 CDS pdxY NC_011740.1 1446020 1446880 D catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase 1446020..1446880 Escherichia fergusonii ATCC 35469 7123507 YP_002382560.1 CDS gst NC_011740.1 1446970 1447572 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95096109, 2185038, 9680481; Product type e : enzyme; glutathionine S-transferase complement(1446970..1447572) Escherichia fergusonii ATCC 35469 7123502 YP_002382561.1 CDS tppB NC_011740.1 1447679 1449184 R mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation; tripeptide transporter permease complement(1447679..1449184) Escherichia fergusonii ATCC 35469 7120622 YP_002382562.1 CDS nth NC_011740.1 1449785 1450420 R DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines; endonuclease III complement(1449785..1450420) Escherichia fergusonii ATCC 35469 7122705 YP_002382563.1 CDS rsxE NC_011740.1 1450420 1451112 R in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex protein RsxE complement(1450420..1451112) Escherichia fergusonii ATCC 35469 7119666 YP_002382564.1 CDS rsxG NC_011740.1 1451115 1451735 R part of membrane-bound complex hought to be involved in electron transport to nitrogen; electron transport complex protein RnfG complement(1451115..1451735) Escherichia fergusonii ATCC 35469 7121158 YP_002382565.1 CDS rnfD NC_011740.1 1451739 1452797 R RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents; electron transport complex protein RnfD complement(1451739..1452797) Escherichia fergusonii ATCC 35469 7121159 YP_002382566.1 CDS rsxC NC_011740.1 1452798 1454978 R part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfC complement(1452798..1454978) Escherichia fergusonii ATCC 35469 7123818 YP_002382567.1 CDS rsxB NC_011740.1 1454971 1455549 R part of membrane-bound complex thought to be involved in electron transport to nitrogen; electron transport complex protein RnfB complement(1454971..1455549) Escherichia fergusonii ATCC 35469 7121156 YP_002382568.1 CDS rsxA NC_011740.1 1455549 1456130 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10411911, 10637328, 12773378; Product type pm : membrane component; Na(+)-translocating NADH-quinone reductase subunit E complement(1455549..1456130) Escherichia fergusonii ATCC 35469 7123817 YP_002382569.1 CDS EFER_1417 NC_011740.1 1456207 1456647 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1456207..1456647) Escherichia fergusonii ATCC 35469 7121155 YP_002382570.1 CDS ydgT NC_011740.1 1456739 1456954 R YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes; oriC-binding nucleoid-associated protein complement(1456739..1456954) Escherichia fergusonii ATCC 35469 7120347 YP_002382571.1 CDS ydgJ NC_011740.1 1457588 1458628 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; oxidoreductase 1457588..1458628 Escherichia fergusonii ATCC 35469 7122706 YP_002382572.1 CDS add NC_011740.1 1458674 1459780 R catalyzes the formation of inosine from adenosine; adenosine deaminase complement(1458674..1459780) Escherichia fergusonii ATCC 35469 7122704 YP_002382573.1 CDS malY NC_011740.1 1459784 1460956 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1856179, 7665481, 10698925; Product type e : enzyme; C-S lyase complement(1459784..1460956) Escherichia fergusonii ATCC 35469 7122272 YP_002382574.1 CDS EFER_1422 NC_011740.1 1460966 1461121 R Evidence 2b : Function of strongly homologous gene; PubMedId : 1856179, 2670898; Product type e : enzyme; hypothetical protein complement(1460966..1461121) Escherichia fergusonii ATCC 35469 7121228 YP_002382575.1 CDS ydgA NC_011740.1 1461222 1462799 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1461222..1462799) Escherichia fergusonii ATCC 35469 7123143 YP_002382576.1 CDS manA NC_011740.1 1462826 1464061 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 82100097, 6397402; Product type e : enzyme; mannose-6-phosphate isomerase complement(1462826..1464061) Escherichia fergusonii ATCC 35469 7122699 YP_002382577.1 CDS fumA NC_011740.1 1464197 1465843 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88193096, 88268900, 92011457, 3005475, 6328431, 9298646; Product type e : enzyme; fumarate hydratase 1464197..1465843 Escherichia fergusonii ATCC 35469 7123831 YP_002382578.1 CDS fumC NC_011740.1 1465997 1467400 D class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 1465997..1467400 Escherichia fergusonii ATCC 35469 7120153 YP_002382579.1 CDS tus NC_011740.1 1467397 1468326 R binds to DNA replication terminator sequences to prevent passage of replication forks; DNA replication terminus site-binding protein complement(1467397..1468326) Escherichia fergusonii ATCC 35469 7120155 YP_002382580.1 CDS rstB NC_011740.1 1468478 1469764 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93086426, 1495392, 1925016, 2646639; Product type r : regulator; sensor protein RstB complement(1468478..1469764) Escherichia fergusonii ATCC 35469 7122606 YP_002382581.1 CDS rstA NC_011740.1 1469777 1470538 R response regulator in two-component regulatory system with RstB; DNA-binding transcriptional regulator RstA complement(1469777..1470538) Escherichia fergusonii ATCC 35469 7121153 YP_002382582.1 CDS ydgC NC_011740.1 1470621 1470962 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1470621..1470962 Escherichia fergusonii ATCC 35469 7121152 YP_002382583.1 CDS folM NC_011740.1 1470959 1471681 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14617668; Product type e : enzyme; short chain dehydrogenase complement(1470959..1471681) Escherichia fergusonii ATCC 35469 7122700 YP_002382584.1 CDS ydgI NC_011740.1 1471716 1473098 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1311296; Product type pt : transporter; arginine/ornithine antiporter transporter complement(1471716..1473098) Escherichia fergusonii ATCC 35469 7123005 YP_002382585.1 CDS ydgH NC_011740.1 1473286 1474230 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1473286..1474230) Escherichia fergusonii ATCC 35469 7122703 YP_002382586.1 CDS pntA NC_011740.1 1474735 1476279 D forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm; NAD(P) transhydrogenase subunit alpha 1474735..1476279 Escherichia fergusonii ATCC 35469 7122702 YP_002382587.1 CDS pntB NC_011740.1 1476290 1477678 D catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme; pyridine nucleotide transhydrogenase 1476290..1477678 Escherichia fergusonii ATCC 35469 7120094 YP_002382588.1 CDS EFER_1436 NC_011740.1 1477835 1480003 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1477835..1480003 Escherichia fergusonii ATCC 35469 7123643 YP_002382589.1 CDS ydgD NC_011740.1 1479994 1480815 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; metallopeptidase complement(1479994..1480815) Escherichia fergusonii ATCC 35469 7120348 YP_002382590.1 CDS asr NC_011740.1 1481085 1481396 R Evidence 2b : Function of strongly homologous gene; Product type ph : phenotype; Acid shock protein , protein complement(1481085..1481396) Escherichia fergusonii ATCC 35469 7122701 YP_002382591.1 CDS ynfM NC_011740.1 1481916 1483169 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; MFS superfamily transporter complement(1481916..1483169) Escherichia fergusonii ATCC 35469 7120572 YP_002382592.1 CDS ynfL NC_011740.1 1483290 1484189 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator 1483290..1484189 Escherichia fergusonii ATCC 35469 7121711 YP_002382593.1 CDS EFER_1441 NC_011740.1 1484205 1484390 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1484205..1484390 Escherichia fergusonii ATCC 35469 7121710 YP_002382594.1 CDS dgsA NC_011740.1 1484318 1485538 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10318813, 20490366, 6989798, 99340206, 99395104, 99398866, 7766024; Product type r : regulator; DNA-binding transcriptional repressor 1484318..1485538 Escherichia fergusonii ATCC 35469 7120349 YP_002382595.1 CDS ynfK NC_011740.1 1485663 1486358 D DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 1485663..1486358 Escherichia fergusonii ATCC 35469 7123550 YP_002382596.1 CDS clcB NC_011740.1 1486311 1487609 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; voltage-gated ClC-type chloride channel ClcB complement(1486311..1487609) Escherichia fergusonii ATCC 35469 7121709 YP_002382597.1 CDS EFER_1445 NC_011740.1 1487708 1488928 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter ATP/GTP-binding protein complement(1487708..1488928) Escherichia fergusonii ATCC 35469 7120902 YP_002382598.1 CDS EFER_1446 NC_011740.1 1488850 1489500 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter membrane protein complement(1488850..1489500) Escherichia fergusonii ATCC 35469 7120350 YP_002382599.1 CDS EFER_1447 NC_011740.1 1489510 1490412 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter substrate-binding protein complement(1489510..1490412) Escherichia fergusonii ATCC 35469 7120351 YP_002382600.1 CDS EFER_1448 NC_011740.1 1490437 1491171 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter membrane protein complement(1490437..1491171) Escherichia fergusonii ATCC 35469 7120352 YP_002382601.1 CDS ydcY NC_011740.1 1491480 1491713 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1491480..1491713 Escherichia fergusonii ATCC 35469 7120353 YP_002382602.1 CDS ydcZ NC_011740.1 1491714 1492163 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(1491714..1492163) Escherichia fergusonii ATCC 35469 7122682 YP_002382603.1 CDS yncA NC_011740.1 1492163 1492912 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; acyl-CoA N-acyltransferase complement(1492163..1492912) Escherichia fergusonii ATCC 35469 7122683 YP_002382604.1 CDS yncB NC_011740.1 1492859 1493896 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; oxidoreductase 1492859..1493896 Escherichia fergusonii ATCC 35469 7121698 YP_002382605.1 CDS yncC NC_011740.1 1494095 1494760 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11004173; Product type pr : regulator; DNA-binding transcriptional regulator 1494095..1494760 Escherichia fergusonii ATCC 35469 7121699 YP_002382606.1 CDS yncD NC_011740.1 1494796 1496898 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type prc : receptor; iron outer membrane receptor complement(1494796..1496898) Escherichia fergusonii ATCC 35469 7123362 YP_002382607.1 CDS yncE NC_011740.1 1497140 1498201 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1497140..1498201 Escherichia fergusonii ATCC 35469 7121700 YP_002382608.1 CDS ansP NC_011740.1 1498316 1499815 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 76005443; Product type t : transporter; L-asparagine transporter complement(1498316..1499815) Escherichia fergusonii ATCC 35469 7121701 YP_002382609.1 CDS yncG NC_011740.1 1500097 1500714 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; glutathione S-transferase-like protein 1500097..1500714 Escherichia fergusonii ATCC 35469 7120520 YP_002382610.1 CDS EFER_1458 NC_011740.1 1501052 1501252 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1501052..1501252 Escherichia fergusonii ATCC 35469 7123910 YP_002382611.1 CDS EFER_1459 NC_011740.1 1501274 1501606 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1501274..1501606 Escherichia fergusonii ATCC 35469 7123144 YP_002382612.1 CDS EFER_1460 NC_011740.1 1501651 1501971 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1501651..1501971 Escherichia fergusonii ATCC 35469 7120354 YP_002382613.1 CDS EFER_1461 NC_011740.1 1502107 1502496 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1502107..1502496 Escherichia fergusonii ATCC 35469 7120355 YP_002382614.1 CDS EFER_1463 NC_011740.1 1503949 1504305 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1503949..1504305 Escherichia fergusonii ATCC 35469 7124050 YP_002382615.1 CDS EFER_1464 NC_011740.1 1504606 1505088 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1504606..1505088 Escherichia fergusonii ATCC 35469 7123145 YP_002382616.1 CDS EFER_1465 NC_011740.1 1505194 1505535 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1505194..1505535 Escherichia fergusonii ATCC 35469 7120357 YP_002382617.1 CDS EFER_1468 NC_011740.1 1506866 1507450 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1506866..1507450 Escherichia fergusonii ATCC 35469 7122504 YP_002382618.1 CDS yddH NC_011740.1 1507611 1508180 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1507611..1508180) Escherichia fergusonii ATCC 35469 7123146 YP_002382619.1 CDS nhoA NC_011740.1 1508484 1509200 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20267568; Product type e : enzyme; N-hydroxyarylamine O-acetyltransferase 1508484..1509200 Escherichia fergusonii ATCC 35469 7122687 YP_002382620.1 CDS yddE NC_011740.1 1509296 1510189 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14611652, 15103639, 2233673; hypothetical protein complement(1509296..1510189) Escherichia fergusonii ATCC 35469 7123203 YP_002382621.1 CDS EFER_1473 NC_011740.1 1510509 1511717 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; mandelate racemase complement(1510509..1511717) Escherichia fergusonii ATCC 35469 7122685 YP_002382622.1 CDS EFER_1474 NC_011740.1 1511964 1513007 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; lacI family transcriptional regulator 1511964..1513007 Escherichia fergusonii ATCC 35469 7120358 YP_002382623.1 CDS ydcE NC_011740.1 1513016 1513297 D 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase 1513016..1513297 Escherichia fergusonii ATCC 35469 7120359 YP_002382624.1 CDS yddH NC_011740.1 1513302 1513871 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1513302..1513871) Escherichia fergusonii ATCC 35469 7122672 YP_002382625.1 CDS nhoA NC_011740.1 1514046 1514891 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20267568; Product type e : enzyme; N-hydroxyarylamine O-acetyltransferase 1514046..1514891 Escherichia fergusonii ATCC 35469 7122688 YP_002382626.1 CDS EFER_1478 NC_011740.1 1515028 1515831 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator complement(1515028..1515831) Escherichia fergusonii ATCC 35469 7120693 YP_002382627.1 CDS catB NC_011740.1 1516005 1517207 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3609743, 2449420, 2215699, 3612800; Product type e : enzyme; Muconate cycloisomerase I 1516005..1517207 Escherichia fergusonii ATCC 35469 7120360 YP_002382628.1 CDS catC NC_011740.1 1517197 1517487 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2449420, 2926818; Product type e : enzyme; Muconolactone delta-isomerase 1517197..1517487 Escherichia fergusonii ATCC 35469 7120859 YP_002382629.1 CDS catA NC_011740.1 1517552 1518478 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3170486, 10801478; Product type e : enzyme; Catechol 1,2-dioxygenase 1517552..1518478 Escherichia fergusonii ATCC 35469 7120860 YP_002382630.1 CDS benA NC_011740.1 1518558 1519940 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1885518, 15514110; Product type e : enzyme; Benzoate 1,2-dioxygenase subunit alpha 1518558..1519940 Escherichia fergusonii ATCC 35469 7123765 YP_002382631.1 CDS benB NC_011740.1 1519940 1520425 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1885518, 15514110; Product type e : enzyme; benzoate 1,2-dioxygenase subunit beta 1519940..1520425 Escherichia fergusonii ATCC 35469 7123903 YP_002382632.1 CDS benC NC_011740.1 1520432 1521451 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1885518, 15514110; Product type e : enzyme; benzoate 1,2-dioxygenase ferredoxin reductase subunit 1520432..1521451 Escherichia fergusonii ATCC 35469 7121657 YP_002382633.1 CDS benD NC_011740.1 1521461 1522234 D catalyzes the degradation of 2-hydro-1,2-dihydroxy benzoate to catechol; 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase 1521461..1522234 Escherichia fergusonii ATCC 35469 7121658 YP_002382634.1 CDS EFER_1486 NC_011740.1 1522487 1522630 D Evidence 6 : Doubtful CDS; hypothetical protein 1522487..1522630 Escherichia fergusonii ATCC 35469 7123904 YP_002382635.1 CDS EFER_1487 NC_011740.1 1522739 1523854 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; outer membrane porin protein complement(1522739..1523854) Escherichia fergusonii ATCC 35469 7120361 YP_002382636.1 CDS yddG NC_011740.1 1524193 1525017 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12410826; Product type t : transporter; hypothetical protein complement(1524193..1525017) Escherichia fergusonii ATCC 35469 7120362 YP_002382637.1 CDS fdnG NC_011740.1 1525306 1528353 D Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; formate dehydrogenase-N subunit alpha 1525306..1528353 Escherichia fergusonii ATCC 35469 7122686 YP_002382638.1 CDS fdnH NC_011740.1 1528366 1529250 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 76005553, 90375017, 92332427, 11884747, 1834669; Product type c : carrier; formate dehydrogenase-N, Fe-S subunit beta 1528366..1529250 Escherichia fergusonii ATCC 35469 7119996 YP_002382639.1 CDS fdnI NC_011740.1 1529243 1529896 D nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase; formate dehydrogenase-N subunit gamma 1529243..1529896 Escherichia fergusonii ATCC 35469 7119997 YP_002382640.1 CDS EFER_1494 NC_011740.1 1530231 1530509 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1530231..1530509) Escherichia fergusonii ATCC 35469 7122689 YP_002382641.1 CDS adhP NC_011740.1 1530695 1531705 R similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase complement(1530695..1531705) Escherichia fergusonii ATCC 35469 7123147 YP_002382642.1 CDS sfcA NC_011740.1 1531839 1533536 R malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase complement(1531839..1533536) Escherichia fergusonii ATCC 35469 7122275 YP_002382644.1 CDS bdm NC_011740.1 1533932 1534147 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10498711, 13129944; Product type f : factor; biofilm-dependent modulation protein complement(1533932..1534147) Escherichia fergusonii ATCC 35469 7120363 YP_002382645.1 CDS osmC NC_011740.1 1534490 1534921 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14512736, 91350191, 9298646; Product type m : membrane component; osmotically inducible, stress-inducible membrane protein 1534490..1534921 Escherichia fergusonii ATCC 35469 7121656 YP_002382646.1 CDS ydcI NC_011740.1 1535156 1536079 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator complement(1535156..1536079) Escherichia fergusonii ATCC 35469 7119702 YP_002382647.1 CDS pcaG NC_011740.1 1536269 1536889 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7990141, 3194022, 8407791; Product type e : enzyme; protocatechuate 3,4-dioxygenase subunit alpha complement(1536269..1536889) Escherichia fergusonii ATCC 35469 7122674 YP_002382648.1 CDS pcaH NC_011740.1 1536886 1537644 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7990141, 3194022, 8407791; Product type e : enzyme; protocatechuate 3,4-dioxygenase subunit beta complement(1536886..1537644) Escherichia fergusonii ATCC 35469 7122562 YP_002382649.1 CDS ydcJ NC_011740.1 1537855 1539198 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1537855..1539198 Escherichia fergusonii ATCC 35469 7124061 YP_002382650.1 CDS mdoD NC_011740.1 1539516 1541141 D involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans; glucan biosynthesis protein D 1539516..1541141 Escherichia fergusonii ATCC 35469 7122675 YP_002382651.1 CDS ydcH NC_011740.1 1541284 1541520 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1541284..1541520 Escherichia fergusonii ATCC 35469 7123835 YP_002382652.1 CDS rimL NC_011740.1 1541574 1542122 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2671655; Product type e : enzyme; ribosomal-protein-L7/L12-serine acetyltransferase 1541574..1542122 Escherichia fergusonii ATCC 35469 7122673 YP_002382653.1 CDS ydcK NC_011740.1 1542114 1543094 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transferase complement(1542114..1543094) Escherichia fergusonii ATCC 35469 7123864 YP_002382654.1 CDS tehB NC_011740.1 1543310 1543906 D with TehA confers resistance to tellurite; tellurite resistance protein TehB 1543310..1543906 Escherichia fergusonii ATCC 35469 7122676 YP_002382655.1 CDS ydcL NC_011740.1 1544049 1544717 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1544049..1544717 Escherichia fergusonii ATCC 35469 7121984 YP_002382656.1 CDS ydcP NC_011740.1 1544844 1546805 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; peptidase 1544844..1546805 Escherichia fergusonii ATCC 35469 7124085 YP_002382657.1 CDS EFER_1511 NC_011740.1 1547421 1547942 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1547421..1547942 Escherichia fergusonii ATCC 35469 7122678 YP_002382658.1 CDS yncJ NC_011740.1 1548036 1548266 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1548036..1548266) Escherichia fergusonii ATCC 35469 7120364 YP_002382659.1 CDS ydcR NC_011740.1 1548413 1549819 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15223311; Product type pr : regulator; DNA-binding transcriptional regulator 1548413..1549819 Escherichia fergusonii ATCC 35469 7121702 YP_002382660.1 CDS ydcS NC_011740.1 1550064 1551209 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11683869; Product type pt : transporter; spermidine/putrescine ABC transporter substrate-binding protein 1550064..1551209 Escherichia fergusonii ATCC 35469 7124086 YP_002382661.1 CDS ydcT NC_011740.1 1551227 1552240 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; spermidine/putrescine ABC transporter ATP-binding protein 1551227..1552240 Escherichia fergusonii ATCC 35469 7122679 YP_002382662.1 CDS ydcU NC_011740.1 1552241 1553182 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; spermidine/putrescine ABC transporter permease 1552241..1553182 Escherichia fergusonii ATCC 35469 7122680 YP_002382663.1 CDS ydcV NC_011740.1 1553172 1553966 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; spermidine/putrescine ABC transporter permease 1553172..1553966 Escherichia fergusonii ATCC 35469 7123516 YP_002382664.1 CDS ydcW NC_011740.1 1553988 1555412 D catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation; gamma-aminobutyraldehyde dehydrogenase 1553988..1555412 Escherichia fergusonii ATCC 35469 7123517 YP_002382665.1 CDS ydcX NC_011740.1 1555834 1556016 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1555834..1556016 Escherichia fergusonii ATCC 35469 7122681 YP_002382666.1 CDS ynfD NC_011740.1 1556064 1556369 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1556064..1556369) Escherichia fergusonii ATCC 35469 7124087 YP_002382667.1 CDS ynfC NC_011740.1 1556474 1557184 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1556474..1557184 Escherichia fergusonii ATCC 35469 7121708 YP_002382668.1 CDS speG NC_011740.1 1557189 1557749 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94357898; Product type e : enzyme; spermidine N1-acetyltransferase complement(1557189..1557749) Escherichia fergusonii ATCC 35469 7123912 YP_002382669.1 CDS ynfB NC_011740.1 1557780 1558121 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1557780..1558121) Escherichia fergusonii ATCC 35469 7121807 YP_002382670.1 CDS ynfA NC_011740.1 1558268 1558594 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1558268..1558594 Escherichia fergusonii ATCC 35469 7121707 YP_002382671.1 CDS rspA NC_011740.1 1558703 1559917 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 93341455, 94310441; Product type pe : enzyme; enolase/dehydratase 1558703..1559917 Escherichia fergusonii ATCC 35469 7121706 YP_002382672.1 CDS rspB NC_011740.1 1559905 1560948 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7545940; Product type pe : enzyme; dehydrogenase 1559905..1560948 Escherichia fergusonii ATCC 35469 7123274 YP_002382673.1 CDS EFER_1527 NC_011740.1 1560992 1561966 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; TRAP dicarboxylate transporter subunit DctP 1560992..1561966 Escherichia fergusonii ATCC 35469 7123275 YP_002382674.1 CDS EFER_1528 NC_011740.1 1561997 1562494 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; TRAP dicarboxylate transporter subunit DctQ 1561997..1562494 Escherichia fergusonii ATCC 35469 7120365 YP_002382675.1 CDS EFER_1529 NC_011740.1 1562519 1563802 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; TRAP dicarboxylate transporter subunit DctM 1562519..1563802 Escherichia fergusonii ATCC 35469 7120366 YP_002382676.1 CDS dctP NC_011740.1 1563862 1564839 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; TRAP dicarboxylate transporter subunit DctP 1563862..1564839 Escherichia fergusonii ATCC 35469 7120367 YP_002382677.1 CDS EFER_1531 NC_011740.1 1564888 1565364 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; TRAP dicarboxylate transporter subunit DctQ 1564888..1565364 Escherichia fergusonii ATCC 35469 7122875 YP_002382678.1 CDS EFER_1532 NC_011740.1 1565277 1566635 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; TRAP dicarboxylate transporter subunit DctM 1565277..1566635 Escherichia fergusonii ATCC 35469 7120368 YP_002382679.1 CDS ydfI NC_011740.1 1566699 1568186 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; mannonate dehydrogenase 1566699..1568186 Escherichia fergusonii ATCC 35469 7120369 YP_002382680.1 CDS ydfZ NC_011740.1 1568275 1568628 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1568275..1568628) Escherichia fergusonii ATCC 35469 7122696 YP_002382681.1 CDS ydfH NC_011740.1 1568782 1569468 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator complement(1568782..1569468) Escherichia fergusonii ATCC 35469 7124091 YP_002382682.1 CDS ydfG NC_011740.1 1569555 1570301 R NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine; 3-hydroxy acid dehydrogenase complement(1569555..1570301) Escherichia fergusonii ATCC 35469 7123519 YP_002382683.1 CDS dcp NC_011740.1 1570398 1572479 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 216006, 8226676; Product type e : enzyme; dipeptidyl carboxypeptidase II 1570398..1572479 Escherichia fergusonii ATCC 35469 7123518 YP_002382684.1 CDS ydeJ NC_011740.1 1572523 1573056 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1572523..1573056) Escherichia fergusonii ATCC 35469 7122871 YP_002382685.1 CDS ydeI NC_011740.1 1573211 1573603 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1573211..1573603 Escherichia fergusonii ATCC 35469 7122695 YP_002382686.1 CDS ydeH NC_011740.1 1573742 1574707 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1573742..1574707 Escherichia fergusonii ATCC 35469 7122694 YP_002382687.1 CDS ydeE NC_011740.1 1574919 1576106 R YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters; MFS-type transporter YdeE complement(1574919..1576106) Escherichia fergusonii ATCC 35469 7122693 YP_002382688.1 CDS eamA NC_011740.1 1576299 1577192 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20305052; Product type t : transporter; O-acetylserine/cysteine export protein 1576299..1577192 Escherichia fergusonii ATCC 35469 7122692 YP_002382689.1 CDS marB NC_011740.1 1577329 1577547 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8383113; Product type t : transporter; hypothetical protein complement(1577329..1577547) Escherichia fergusonii ATCC 35469 7122932 YP_002382690.1 CDS marA NC_011740.1 1577555 1577986 R transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF; DNA-binding transcriptional activator MarA complement(1577555..1577986) Escherichia fergusonii ATCC 35469 7121234 YP_002382691.1 CDS marR NC_011740.1 1577959 1578393 R Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes; DNA-binding transcriptional repressor MarR complement(1577959..1578393) Escherichia fergusonii ATCC 35469 7121233 YP_002382692.1 CDS marC NC_011740.1 1578613 1579278 D protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function; multiple drug resistance protein MarC 1578613..1579278 Escherichia fergusonii ATCC 35469 7123834 YP_002382693.1 CDS ydeA NC_011740.1 1579313 1580506 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10094697, 99369894, 8383113, 10438792; Product type t : transporter; sugar efflux transporter complement(1579313..1580506) Escherichia fergusonii ATCC 35469 7123833 YP_002382694.1 CDS yneJ NC_011740.1 1580598 1581464 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator complement(1580598..1581464) Escherichia fergusonii ATCC 35469 7122691 YP_002382695.1 CDS yneI NC_011740.1 1581562 1582938 D in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; succinate semialdehyde dehydrogenase 1581562..1582938 Escherichia fergusonii ATCC 35469 7123364 YP_002382696.1 CDS yneH NC_011740.1 1583014 1583940 D catalyzes the formation of glutamate from glutamine; glutaminase 1583014..1583940 Escherichia fergusonii ATCC 35469 7121705 YP_002382697.1 CDS yneG NC_011740.1 1583940 1584296 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1583940..1584296 Escherichia fergusonii ATCC 35469 7121704 YP_002382698.1 CDS yneF NC_011740.1 1584406 1585839 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; membrane-associated diguanylate cyclase 1584406..1585839 Escherichia fergusonii ATCC 35469 7123363 YP_002382699.1 CDS uxaB NC_011740.1 1585988 1587439 D catalyzes the formation of D-tagaturonate from D-altronate; altronate oxidoreductase 1585988..1587439 Escherichia fergusonii ATCC 35469 7123911 YP_002382700.1 CDS yneE NC_011740.1 1587635 1588549 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1587635..1588549 Escherichia fergusonii ATCC 35469 7123513 YP_002382701.1 CDS tam NC_011740.1 1588553 1589311 R catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase complement(1588553..1589311) Escherichia fergusonii ATCC 35469 7121703 YP_002382702.1 CDS ydcM NC_011740.1 1589400 1590608 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transposase complement(1589400..1590608) Escherichia fergusonii ATCC 35469 7121973 YP_002382703.1 CDS EFER_1557 NC_011740.1 1590586 1590732 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1590586..1590732) Escherichia fergusonii ATCC 35469 7122677 YP_002382704.1 CDS EFER_1558 NC_011740.1 1590616 1590984 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transposase, IS605 family, IS200 group 1590616..1590984 Escherichia fergusonii ATCC 35469 7120370 YP_002382705.1 CDS lsrG NC_011740.1 1591117 1591407 R Evidence 4 : Homologs of previously reported genes of unknown function; autoinducer-2 (AI-2) modifying protein LsrG complement(1591117..1591407) Escherichia fergusonii ATCC 35469 7120371 YP_002382706.1 CDS lsrF NC_011740.1 1591431 1592306 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; aldolase complement(1591431..1592306) Escherichia fergusonii ATCC 35469 7121211 YP_002382707.1 CDS lsrB NC_011740.1 1592333 1593355 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11722742; Product type t : transporter; AI2 ABC transporter periplasmic-binding protein complement(1592333..1593355) Escherichia fergusonii ATCC 35469 7121210 YP_002382708.1 CDS lsrD NC_011740.1 1593367 1594359 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11722742; Product type t : transporter; AI2 ABC transporter membrane protein complement(1593367..1594359) Escherichia fergusonii ATCC 35469 7121207 YP_002382709.1 CDS lsrC NC_011740.1 1594359 1595387 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11722742; Product type t : transporter; AI2 ABC transporter membrane protein complement(1594359..1595387) Escherichia fergusonii ATCC 35469 7121209 YP_002382710.1 CDS ego NC_011740.1 1595381 1596916 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12657059, 11722742; Product type t : transporter; AI2 ABC transporter ATP-binding protein complement(1595381..1596916) Escherichia fergusonii ATCC 35469 7121208 YP_002382711.1 CDS lsrR NC_011740.1 1597165 1598118 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16321939, 15601708, 14622426; Product type r : regulator; DNA-binding transcriptional regulator 1597165..1598118 Escherichia fergusonii ATCC 35469 7122941 YP_002382712.1 CDS lsrK NC_011740.1 1598197 1599789 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15601708, 14622426; Product type e : enzyme; autoinducer-2 (AI-2) kinase 1598197..1599789 Escherichia fergusonii ATCC 35469 7121213 YP_002382713.1 CDS EFER_1568 NC_011740.1 1599987 1600583 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8253194; Product type pe : enzyme; glutathione S-transferase family protein complement(1599987..1600583) Escherichia fergusonii ATCC 35469 7121212 YP_002382714.1 CDS EFER_1569 NC_011740.1 1601925 1602725 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1601925..1602725 Escherichia fergusonii ATCC 35469 7120372 YP_002382715.1 CDS EFER_1570 NC_011740.1 1602900 1604918 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; invasin-like protein; protein complement(1602900..1604918) Escherichia fergusonii ATCC 35469 7123148 YP_002382716.1 CDS EFER_1571 NC_011740.1 1605041 1605910 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; hypothetical protein complement(1605041..1605910) Escherichia fergusonii ATCC 35469 7123689 YP_002382717.1 CDS yddA NC_011740.1 1606431 1608086 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; multidrug ABC transporter permease/ATP-binding protein 1606431..1608086 Escherichia fergusonii ATCC 35469 7120373 YP_002382718.1 CDS yddB NC_011740.1 1608123 1610495 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; porin protein 1608123..1610495 Escherichia fergusonii ATCC 35469 7122684 YP_002382719.1 CDS pqqL NC_011740.1 1610545 1613343 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9097039, 9278503, 16738553; Product type pe : enzyme; zinc protease 1610545..1613343 Escherichia fergusonii ATCC 35469 7124088 YP_002382720.1 CDS gadB NC_011740.1 1613670 1615070 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12912902, 92155241, 92394884, 99406302, 8455549; Product type e : enzyme; glutamate decarboxylase 1613670..1615070 Escherichia fergusonii ATCC 35469 7120121 YP_002382721.1 CDS gadC NC_011740.1 1615255 1616790 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15795232, 15489450; Product type t : transporter; glutamate:gamma-aminobutyric acid antiporter 1615255..1616790 Escherichia fergusonii ATCC 35469 7120162 YP_002382722.1 CDS yddW NC_011740.1 1616827 1618251 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10960106; Product type lp : lipoprotein; lipoprotein 1616827..1618251 Escherichia fergusonii ATCC 35469 7123654 YP_002382723.1 CDS yddV NC_011740.1 1618450 1619841 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16497924, 15142243; Product type pe : enzyme; diguanylate cyclase YddV 1618450..1619841 Escherichia fergusonii ATCC 35469 7124089 YP_002382724.1 CDS dos NC_011740.1 1619866 1622271 D heme-regulated phosphodiesterase with phosphodiesterase activity with cAMP but not with cGMP, bis(p-nitrophenyl) phosphate or p-nitrophenyl phosphate; cAMP phosphodiesterase 1619866..1622271 Escherichia fergusonii ATCC 35469 7122690 YP_002382725.1 CDS frmA NC_011740.1 1622329 1623462 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15466022, 87172301, 1731906; Product type e : enzyme; alcohol dehydrogenase complement(1622329..1623462) Escherichia fergusonii ATCC 35469 7122915 YP_002382726.1 CDS yohL NC_011740.1 1623479 1623889 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1623479..1623889) Escherichia fergusonii ATCC 35469 7124142 YP_002382727.1 CDS cybB NC_011740.1 1624023 1624589 R B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm; cytochrome b561 complement(1624023..1624589) Escherichia fergusonii ATCC 35469 7121173 YP_002382728.1 CDS gapC NC_011740.1 1624659 1625741 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9622357, 9019141, 1917845, 3780374; Product type e : enzyme; glyceraldehyde-3-phosphate dehydrogenase 1624659..1625741 Escherichia fergusonii ATCC 35469 7122837 YP_002382729.1 CDS ydcF NC_011740.1 1625791 1626591 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1625791..1626591) Escherichia fergusonii ATCC 35469 7123656 YP_002382730.1 CDS EFER_1587 NC_011740.1 1627006 1627863 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1627006..1627863) Escherichia fergusonii ATCC 35469 7124084 YP_002382731.1 CDS hrpA NC_011740.1 1628076 1631921 R involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain; ATP-dependent RNA helicase HrpA complement(1628076..1631921) Escherichia fergusonii ATCC 35469 7120374 YP_002382732.1 CDS azoR NC_011740.1 1632179 1632784 D FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds; azoreductase 1632179..1632784 Escherichia fergusonii ATCC 35469 7123444 YP_002382733.1 CDS ynbD NC_011740.1 1632838 1634130 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; membrane associated phosphatase complement(1632838..1634130) Escherichia fergusonii ATCC 35469 7121641 YP_002382734.1 CDS ynbC NC_011740.1 1634144 1635901 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hydrolase complement(1634144..1635901) Escherichia fergusonii ATCC 35469 7121696 YP_002382735.1 CDS ynbB NC_011740.1 1635917 1636813 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; membrane associated CTP-phosphosubstrate transferase complement(1635917..1636813) Escherichia fergusonii ATCC 35469 7121695 YP_002382736.1 CDS ynbA NC_011740.1 1636813 1637418 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(1636813..1637418) Escherichia fergusonii ATCC 35469 7121694 YP_002382737.1 CDS ydbD NC_011740.1 1637589 1639895 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1637589..1639895) Escherichia fergusonii ATCC 35469 7123909 YP_002382738.1 CDS ydbC NC_011740.1 1639959 1640819 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; oxidoreductase complement(1639959..1640819) Escherichia fergusonii ATCC 35469 7119959 YP_002382739.1 CDS paaY NC_011740.1 1641062 1641652 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12846838, 9748275; Product type pe : enzyme; hexapeptide repeat acetyltransferase complement(1641062..1641652) Escherichia fergusonii ATCC 35469 7119958 YP_002382740.1 CDS paaX NC_011740.1 1641634 1642584 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12846838, 20229831, 9748275; Product type r : regulator; phenylacetic acid degradation DNA-binding transcriptional repressor complement(1641634..1642584) Escherichia fergusonii ATCC 35469 7123496 YP_002382741.1 CDS paaK NC_011740.1 1642684 1643997 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12846838, 9748275, 10766858; Product type e : enzyme; phenylacetyl-CoA ligase complement(1642684..1643997) Escherichia fergusonii ATCC 35469 7122549 YP_002382742.1 CDS paaE NC_011740.1 1644024 1645229 R catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; beta-ketoadipyl CoA thiolase complement(1644024..1645229) Escherichia fergusonii ATCC 35469 7122548 YP_002382743.1 CDS paaI NC_011740.1 1645229 1645651 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16464851, 12846838, 9748275; Product type e : enzyme; phenylacetate pathway hotdog-fold thioesterase complement(1645229..1645651) Escherichia fergusonii ATCC 35469 7119711 YP_002382744.1 CDS paaH NC_011740.1 1645641 1647068 R converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation; 3-hydroxyacyl-CoA dehydrogenase complement(1645641..1647068) Escherichia fergusonii ATCC 35469 7122668 YP_002382745.1 CDS paaG NC_011740.1 1647070 1647858 R Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase complement(1647070..1647858) Escherichia fergusonii ATCC 35469 7119714 YP_002382746.1 CDS paaF NC_011740.1 1647858 1648625 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12846838, 9748275, 10766858; Product type e : enzyme; enoyl-CoA hydratase-isomerase complement(1647858..1648625) Escherichia fergusonii ATCC 35469 7119713 YP_002382747.1 CDS paaJ NC_011740.1 1648622 1649692 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 17259607, 11260461, 12846838, 9748275; Product type e : enzyme; subunit of the phenylacetly-CoA oxygenase/reductase complement(1648622..1649692) Escherichia fergusonii ATCC 35469 7119712 YP_002382748.1 CDS paaD NC_011740.1 1649700 1650197 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12846838, 9748275; Product type pe : enzyme; multicomponent oxygenase/reductase subunit for phenylacetic acid degradation complement(1649700..1650197) Escherichia fergusonii ATCC 35469 7124059 YP_002382749.1 CDS paaC NC_011740.1 1650212 1650958 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12846838, 9748275; Product type pe : enzyme; multicomponent oxygenase/reductase subunit for phenylacetic acid degradation complement(1650212..1650958) Escherichia fergusonii ATCC 35469 7123581 YP_002382750.1 CDS paaB NC_011740.1 1650967 1651254 R with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation; phenylacetate-CoA oxygenase subunit PaaB complement(1650967..1651254) Escherichia fergusonii ATCC 35469 7119710 YP_002382751.1 CDS paaA NC_011740.1 1651266 1652195 R with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; phenylacetate-CoA oxygenase subunit PaaA complement(1651266..1652195) Escherichia fergusonii ATCC 35469 7119709 YP_002382752.1 CDS maoC NC_011740.1 1652480 1654525 D catalyzes the ring cleavage reaction in phenylacetate degradation and the formation of 3-hydroxyacyl-CoA from crotonyl-CoA; bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase 1652480..1654525 Escherichia fergusonii ATCC 35469 7119708 YP_002382753.1 CDS EFER_1610 NC_011740.1 1654579 1654743 D Evidence 6 : Doubtful CDS; hypothetical protein 1654579..1654743 Escherichia fergusonii ATCC 35469 7121231 YP_002382754.1 CDS tynA NC_011740.1 1654773 1657046 D catalyzes the formation of phenylacetaldehyde from 2-phenylethylamine; tyramine oxidase 1654773..1657046 Escherichia fergusonii ATCC 35469 7120375 YP_002382755.1 CDS feaB NC_011740.1 1657105 1658604 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96213037, 97263463, 9043126; Product type e : enzyme; phenylacetaldehyde dehydrogenase complement(1657105..1658604) Escherichia fergusonii ATCC 35469 7122611 YP_002382756.1 CDS feaR NC_011740.1 1658840 1659745 D activator of genes involved in phenylacetic acid catabolism; DNA-binding transcriptional activator FeaR 1658840..1659745 Escherichia fergusonii ATCC 35469 7123627 YP_002382757.1 CDS EFER_1614 NC_011740.1 1659857 1660177 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1659857..1660177) Escherichia fergusonii ATCC 35469 7123628 YP_002382758.1 CDS ydbL NC_011740.1 1660234 1660560 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1660234..1660560) Escherichia fergusonii ATCC 35469 7120376 YP_002382759.1 CDS ynbE NC_011740.1 1660565 1660750 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; lipoprotein complement(1660565..1660750) Escherichia fergusonii ATCC 35469 7124083 YP_002382760.1 CDS ydbH NC_011740.1 1660747 1663386 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1660747..1663386) Escherichia fergusonii ATCC 35469 7121697 YP_002382761.1 CDS ldhA NC_011740.1 1663595 1664584 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 4297266, 89123040, 90198524, 8349564, 9025293; Product type e : enzyme; fermentative D-lactate dehydrogenase 1663595..1664584 Escherichia fergusonii ATCC 35469 7123619 YP_002382762.1 CDS hslJ NC_011740.1 1664686 1665108 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8349564; Product type f : factor; heat-inducible protein 1664686..1665108 Escherichia fergusonii ATCC 35469 7120819 YP_002382763.1 CDS ydbJ NC_011740.1 1665105 1665371 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1665105..1665371) Escherichia fergusonii ATCC 35469 7122226 YP_002382764.1 CDS EFER_1621 NC_011740.1 1665481 1666635 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1665481..1666635 Escherichia fergusonii ATCC 35469 7122669 YP_002382765.1 CDS ydbK NC_011740.1 1666984 1670508 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9025293; Product type pe : enzyme; 2-oxoacid-flavodoxin 1666984..1670508 Escherichia fergusonii ATCC 35469 7120377 YP_002382766.1 CDS ompN NC_011740.1 1670850 1671983 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9642192; Product type t : transporter; outer membrane pore protein N, non-specific 1670850..1671983 Escherichia fergusonii ATCC 35469 7120931 YP_002382767.1 CDS uspF NC_011740.1 1672123 1672557 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12732303, 12381839, 11849540, 9298646; Product type f : factor; stress-induced protein, ATP-binding protein 1672123..1672557 Escherichia fergusonii ATCC 35469 7123577 YP_002382768.1 CDS ydaO NC_011740.1 1672827 1673762 D TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 1672827..1673762 Escherichia fergusonii ATCC 35469 7124078 YP_002382769.1 CDS dbpA NC_011740.1 1673875 1675248 R exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA; ATP-dependent RNA helicase DbpA complement(1673875..1675248) Escherichia fergusonii ATCC 35469 7123618 YP_002382770.1 CDS EFER_1627 NC_011740.1 1675277 1675450 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1675277..1675450) Escherichia fergusonii ATCC 35469 7122869 YP_002382771.1 CDS EFER_1628 NC_011740.1 1675623 1675769 R Evidence 6 : Doubtful CDS; hypothetical protein complement(1675623..1675769) Escherichia fergusonii ATCC 35469 7121683 YP_002382772.1 CDS zntB NC_011740.1 1675726 1676709 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; zinc transporter complement(1675726..1676709) Escherichia fergusonii ATCC 35469 7123690 YP_002382773.1 CDS ydaM NC_011740.1 1676942 1678180 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1676942..1678180 Escherichia fergusonii ATCC 35469 7119957 YP_002382774.1 CDS pcaC NC_011740.1 1678231 1678638 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2298704; Product type e : enzyme; 4-carboxymuconolactone decarboxylase complement(1678231..1678638) Escherichia fergusonii ATCC 35469 7119956 YP_002382775.1 CDS pcaD NC_011740.1 1678607 1679422 R Evidence 2b : Function of strongly homologous gene; PubMedId : 8181753; Product type e : enzyme; 3-oxoadipate enol-lactonase complement(1678607..1679422) Escherichia fergusonii ATCC 35469 7122560 YP_002382776.1 CDS pcaB NC_011740.1 1679361 1680716 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1390752; Product type e : enzyme; 3-carboxy-cis,cis-muconate cycloisomerase complement(1679361..1680716) Escherichia fergusonii ATCC 35469 7122561 YP_002382777.1 CDS paaJ NC_011740.1 1680723 1681925 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9748275; Product type e : enzyme; Beta-ketoadipyl CoA thiolase complement(1680723..1681925) Escherichia fergusonii ATCC 35469 7123499 YP_002382778.1 CDS pcaJ NC_011740.1 1681935 1682591 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8063101; Product type e : enzyme; 3-oxoadipate CoA-transferase subunit B complement(1681935..1682591) Escherichia fergusonii ATCC 35469 7122547 YP_002382779.1 CDS pcaI NC_011740.1 1682602 1683324 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1624453, 6780551; Product type e : enzyme; 3-oxoadipate CoA-transferase subunit A complement(1682602..1683324) Escherichia fergusonii ATCC 35469 7123500 YP_002382780.1 CDS PcaR NC_011740.1 1683462 1684268 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8083169; Product type r : regulator; Pca regulon regulatory protein 1683462..1684268 Escherichia fergusonii ATCC 35469 7122563 YP_002382781.1 CDS ydaL NC_011740.1 1684269 1684832 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1684269..1684832) Escherichia fergusonii ATCC 35469 7124062 YP_002382782.1 CDS ogt NC_011740.1 1685027 1685542 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88067749, 91161525, 94252990, 98125595, 1520330; Product type e : enzyme; O-6-alkylguanine-DNA:cysteine-protein methyltransferase 1685027..1685542 Escherichia fergusonii ATCC 35469 7120797 YP_002382783.1 CDS fnr NC_011740.1 1685737 1686489 D Global transcription factor that controls the expression of over 100 target genes in response to anoxia; fumarate/nitrate reduction transcriptional regulator 1685737..1686489 Escherichia fergusonii ATCC 35469 7119690 YP_002382784.1 CDS EFER_1641 NC_011740.1 1686610 1689774 R Evidence 2b : Function of strongly homologous gene; PubMedId : 391406; Product type pe : enzyme; transposase, transposon Tn3 complement(1686610..1689774) Escherichia fergusonii ATCC 35469 7123000 YP_002382785.1 CDS EFER_1642 NC_011740.1 1689743 1690336 D Evidence 2b : Function of strongly homologous gene; Product type pe : enzyme; Resolvase transposon Tn3 1689743..1690336 Escherichia fergusonii ATCC 35469 7120379 YP_002382786.1 CDS bla NC_011740.1 1690519 1691379 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 358200, 3019092, 15769331; Product type e : enzyme; Beta-lactamase TEM 1690519..1691379 Escherichia fergusonii ATCC 35469 7120380 YP_002382787.1 CDS uspE NC_011740.1 1691595 1692545 D with UspC and UspD is involved in resistance to UV irradiation; universal stress protein UspE 1691595..1692545 Escherichia fergusonii ATCC 35469 7121673 YP_002382788.1 CDS ynaJ NC_011740.1 1692597 1692944 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(1692597..1692944) Escherichia fergusonii ATCC 35469 7124077 YP_002382789.1 CDS ynaI NC_011740.1 1693096 1694130 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1693096..1694130 Escherichia fergusonii ATCC 35469 7121693 YP_002382790.1 CDS mppA NC_011740.1 1694232 1695845 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10438753, 9495761; Product type t : transporter; murein tripeptide ABC transporter periplasmic-binding protein complement(1694232..1695845) Escherichia fergusonii ATCC 35469 7121692 YP_002382791.1 CDS mpaA NC_011740.1 1696015 1696758 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12511517; Product type e : enzyme; murein peptide amidase A 1696015..1696758 Escherichia fergusonii ATCC 35469 7120960 YP_002382792.1 CDS ycjG NC_011740.1 1696733 1697857 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11747447, 11747448, 7499381; Product type e : enzyme; L-Ala-D/L-Glu epimerase complement(1696733..1697857) Escherichia fergusonii ATCC 35469 7120958 YP_002382793.1 CDS tpx NC_011740.1 1697812 1698318 D antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 1697812..1698318 Escherichia fergusonii ATCC 35469 7119954 YP_002382794.1 CDS tyrR NC_011740.1 1698371 1699912 R regulates genes involved in the biosynthesis and transport of aromatic amino acids; DNA-binding transcriptional regulator TyrR complement(1698371..1699912) Escherichia fergusonii ATCC 35469 7122152 YP_002382795.1 CDS ycjF NC_011740.1 1700060 1701121 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(1700060..1701121) Escherichia fergusonii ATCC 35469 7122614 YP_002382796.1 CDS ycjX NC_011740.1 1701118 1702515 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1701118..1702515) Escherichia fergusonii ATCC 35469 7123080 YP_002382797.1 CDS pspE NC_011740.1 1702640 1702990 R rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide; thiosulfate:cyanide sulfurtransferase complement(1702640..1702990) Escherichia fergusonii ATCC 35469 7119955 YP_002382798.1 CDS pspD NC_011740.1 1703033 1703254 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91295203, 97303082; Product type ph : phenotype; peripheral inner membrane phage-shock protein complement(1703033..1703254) Escherichia fergusonii ATCC 35469 7124019 YP_002382799.1 CDS pspC NC_011740.1 1703263 1703625 R with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock; DNA-binding transcriptional activator PspC complement(1703263..1703625) Escherichia fergusonii ATCC 35469 7122305 YP_002382800.1 CDS pspB NC_011740.1 1703625 1703849 R acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding; phage shock protein B complement(1703625..1703849) Escherichia fergusonii ATCC 35469 7122304 YP_002382801.1 CDS pspA NC_011740.1 1703904 1704572 R involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF; phage shock protein PspA complement(1703904..1704572) Escherichia fergusonii ATCC 35469 7123459 YP_002382802.1 CDS pspF NC_011740.1 1704723 1705712 D transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor; phage shock protein operon transcriptional activator 1704723..1705712 Escherichia fergusonii ATCC 35469 7122303 YP_002382803.1 CDS sapA NC_011740.1 1705827 1707470 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2109018, 9634580; Product type t : transporter; antimicrobial peptide ABC transporter periplasmic-binding protein 1705827..1707470 Escherichia fergusonii ATCC 35469 7122306 YP_002382804.1 CDS sapB NC_011740.1 1707467 1708432 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2109018, 9634580; Product type t : transporter; antimicrobial peptide ABC transporter permease 1707467..1708432 Escherichia fergusonii ATCC 35469 7121190 YP_002382805.1 CDS sapC NC_011740.1 1708419 1709309 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2109018, 9634580; Product type t : transporter; antimicrobial peptide ABC transporter permease 1708419..1709309 Escherichia fergusonii ATCC 35469 7123825 YP_002382806.1 CDS sapD NC_011740.1 1709309 1710301 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2109018, 10720487, 9634580, 1987159; Product type t : transporter; antimicrobial peptide ABC transporter ATP-binding protein 1709309..1710301 Escherichia fergusonii ATCC 35469 7121191 YP_002382807.1 CDS sapF NC_011740.1 1710303 1711109 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2109018, 10720487, 9634580; Product type t : transporter; antimicrobial peptide ABC transporter ATP-binding protein 1710303..1711109 Escherichia fergusonii ATCC 35469 7121192 YP_002382808.1 CDS fabI NC_011740.1 1711231 1712019 D Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase 1711231..1712019 Escherichia fergusonii ATCC 35469 7123826 YP_002382809.1 CDS yciW NC_011740.1 1712241 1713395 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; amidase 1712241..1713395 Escherichia fergusonii ATCC 35469 7119984 YP_002382810.1 CDS rnb NC_011740.1 1713463 1715397 D Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II 1713463..1715397 Escherichia fergusonii ATCC 35469 7119952 YP_002382811.1 CDS gmr NC_011740.1 1715621 1717612 D c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP; RNase II stability modulator 1715621..1717612 Escherichia fergusonii ATCC 35469 7121422 YP_002382812.1 CDS EFER_1669 NC_011740.1 1717767 1717943 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1717767..1717943 Escherichia fergusonii ATCC 35469 7120595 YP_002382813.1 CDS yciT NC_011740.1 1717912 1718745 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16451192; Product type r : regulator; HTH-type transcriptional regulator 1717912..1718745 Escherichia fergusonii ATCC 35469 7120381 YP_002382814.1 CDS osmB NC_011740.1 1719020 1719238 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92078100, 2644204; Product type lp : lipoprotein; lipoprotein 1719020..1719238 Escherichia fergusonii ATCC 35469 7119950 YP_002382815.1 CDS yciH NC_011740.1 1719360 1719689 R involved in start site selection during the initiation of translation; translation initiation factor Sui1 complement(1719360..1719689) Escherichia fergusonii ATCC 35469 7123580 YP_002382816.1 CDS pyrF NC_011740.1 1719686 1720423 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87280048, 3052852; Product type e : enzyme; orotidine-5'-phosphate decarboxylase complement(1719686..1720423) Escherichia fergusonii ATCC 35469 7119943 YP_002382817.1 CDS yciM NC_011740.1 1720614 1721783 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1720614..1721783) Escherichia fergusonii ATCC 35469 7124024 YP_002382818.1 CDS yciS NC_011740.1 1721790 1722098 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(1721790..1722098) Escherichia fergusonii ATCC 35469 7119945 YP_002382819.1 CDS pgpB NC_011740.1 1722249 1723043 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89033893, 92104964; Product type e : enzyme; phosphatidylglycerophosphatase B complement(1722249..1723043) Escherichia fergusonii ATCC 35469 7119949 YP_002382820.1 CDS ribA NC_011740.1 1723202 1723798 D catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 1723202..1723798 Escherichia fergusonii ATCC 35469 7122591 YP_002382821.1 CDS acnA NC_011740.1 1723859 1726534 R Catalyzes the conversion of citrate to isocitrate; aconitate hydratase complement(1723859..1726534) Escherichia fergusonii ATCC 35469 7123316 YP_002382822.1 CDS EFER_1679 NC_011740.1 1726907 1727074 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1726907..1727074 Escherichia fergusonii ATCC 35469 7122260 YP_002382823.1 CDS EFER_1680 NC_011740.1 1727095 1727265 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1727095..1727265) Escherichia fergusonii ATCC 35469 7123691 YP_002382824.1 CDS yciX NC_011740.1 1727266 1727451 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1727266..1727451) Escherichia fergusonii ATCC 35469 7120382 YP_002382825.1 CDS cysB NC_011740.1 1727715 1728689 R LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation; transcriptional regulator CysB complement(1727715..1728689) Escherichia fergusonii ATCC 35469 7119953 YP_002382826.1 CDS topA NC_011740.1 1728898 1731495 R catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I complement(1728898..1731495) Escherichia fergusonii ATCC 35469 7122846 YP_002382827.1 CDS yciN NC_011740.1 1731877 1732128 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3029379, 7567469, 9868784; hypothetical protein 1731877..1732128 Escherichia fergusonii ATCC 35469 7123432 YP_002382828.1 CDS sohB NC_011740.1 1732163 1733212 R SohB; periplasmic protein; member of the peptidase S49 family; periplasmic protease complement(1732163..1733212) Escherichia fergusonii ATCC 35469 7119946 YP_002382829.1 CDS yciK NC_011740.1 1733436 1734194 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; short chain dehydrogenase 1733436..1734194 Escherichia fergusonii ATCC 35469 7123378 YP_002382830.1 CDS btuR NC_011740.1 1734191 1734781 D catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase 1734191..1734781 Escherichia fergusonii ATCC 35469 7123617 YP_002382831.1 CDS rluB NC_011740.1 1734889 1735764 R catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA; 23S rRNA pseudouridylate synthase B complement(1734889..1735764) Escherichia fergusonii ATCC 35469 7121682 YP_002382832.1 CDS yciQ NC_011740.1 1735977 1737872 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(1735977..1737872) Escherichia fergusonii ATCC 35469 7121417 YP_002382833.1 CDS yciO NC_011740.1 1737900 1738520 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1737900..1738520) Escherichia fergusonii ATCC 35469 7119948 YP_002382834.1 CDS yciV NC_011740.1 1738517 1739398 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1738517..1739398) Escherichia fergusonii ATCC 35469 7119947 YP_002382836.1 CDS trpE NC_011740.1 1739671 1741233 D with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1739671..1741233 Escherichia fergusonii ATCC 35469 7122166 YP_002382837.1 CDS trpD NC_011740.1 1741233 1742828 D bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis; bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase 1741233..1742828 Escherichia fergusonii ATCC 35469 7122165 YP_002382838.1 CDS trpC NC_011740.1 1742832 1744190 D monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 1742832..1744190 Escherichia fergusonii ATCC 35469 7122164 YP_002382839.1 CDS trpB NC_011740.1 1744202 1745395 D catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1744202..1745395 Escherichia fergusonii ATCC 35469 7123436 YP_002382840.1 CDS trpA NC_011740.1 1745395 1746201 D catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1745395..1746201 Escherichia fergusonii ATCC 35469 7122163 YP_002382841.1 CDS ompW NC_011740.1 1746252 1746983 R receptor for colicin S4; outer membrane protein W complement(1746252..1746983) Escherichia fergusonii ATCC 35469 7123991 YP_002382842.1 CDS ykgJ NC_011740.1 1747157 1747591 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; ferredoxin 1747157..1747591 Escherichia fergusonii ATCC 35469 7119694 YP_002382843.1 CDS yciC NC_011740.1 1747618 1748361 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1747618..1748361 Escherichia fergusonii ATCC 35469 7123414 YP_002382844.1 CDS yciB NC_011740.1 1748392 1748931 D Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 1748392..1748931 Escherichia fergusonii ATCC 35469 7123616 YP_002382845.1 CDS yciA NC_011740.1 1749039 1749437 D YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins; acyl-CoA thioester hydrolase 1749039..1749437 Escherichia fergusonii ATCC 35469 7119942 YP_002382846.1 CDS tonB NC_011740.1 1749482 1750309 R membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins; transporter complement(1749482..1750309) Escherichia fergusonii ATCC 35469 7119941 YP_002382847.1 CDS yciI NC_011740.1 1750431 1750727 D unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; YciI-like protein 1750431..1750727 Escherichia fergusonii ATCC 35469 7123431 YP_002382848.1 CDS cls NC_011740.1 1751082 1752542 D catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthetase 1751082..1752542 Escherichia fergusonii ATCC 35469 7123693 YP_002382849.1 CDS yciU NC_011740.1 1752576 1752905 D highly acidic protein; the structure of the Haemophilus influenzae protein shows similarity to uracil DNA glycosylase inhibitor (Ugi); binds heat-unstable protein (HU-alpha) which is a histone-like protein; dsDNA-mimic protein 1752576..1752905 Escherichia fergusonii ATCC 35469 7120905 YP_002382850.1 CDS cikL NC_011740.1 1753088 1754083 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; voltage-gated potassium channel complement(1753088..1754083) Escherichia fergusonii ATCC 35469 7119951 YP_002382851.1 CDS oppF NC_011740.1 1753987 1754991 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86111606; Product type t : transporter; oligopeptide ABC transporter ATP-binding protein complement(1753987..1754991) Escherichia fergusonii ATCC 35469 7120894 YP_002382852.1 CDS oppD NC_011740.1 1754988 1756001 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86111606; Product type t : transporter; oligopeptide transporter ATP-binding protein complement(1754988..1756001) Escherichia fergusonii ATCC 35469 7119701 YP_002382853.1 CDS oppC NC_011740.1 1756013 1756921 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86111606; Product type t : transporter; oligopeptide ABC transporter membrane protein complement(1756013..1756921) Escherichia fergusonii ATCC 35469 7119700 YP_002382854.1 CDS oppB NC_011740.1 1756936 1757856 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86111606, 93106975, 2187863; Product type t : transporter; oligopeptide transporter permease complement(1756936..1757856) Escherichia fergusonii ATCC 35469 7123034 YP_002382855.1 CDS oppA NC_011740.1 1757941 1759572 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20256410, 86111605, 90256748, 92325017, 2015910, 9298646, 9600841, 2187863, 8740179, 9740056, 10972807; Product type t : transporter; oligopeptide ABC transporter substrate-binding protein complement(1757941..1759572) Escherichia fergusonii ATCC 35469 7119699 YP_002382856.1 CDS ychE NC_011740.1 1760432 1761079 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(1760432..1761079) Escherichia fergusonii ATCC 35469 7119698 YP_002382857.1 CDS adhE NC_011740.1 1761556 1764231 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12783863, 4301680, 89291706, 91200315; Product type e : enzyme; bifunctional acetaldehyde-CoA/alcohol dehydrogenase 1761556..1764231 Escherichia fergusonii ATCC 35469 7123076 YP_002382858.1 CDS tdk NC_011740.1 1765839 1766492 R catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase complement(1765839..1766492) Escherichia fergusonii ATCC 35469 7120388 YP_002382859.1 CDS hns NC_011740.1 1767151 1767564 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89056689, 94335643, 95267838, 95286558, 99355427, 2404280, 11298273; Product type r : regulator; global DNA-binding transcriptional dual regulator H-NS 1767151..1767564 Escherichia fergusonii ATCC 35469 7123959 YP_002382860.1 CDS galU NC_011740.1 1767697 1768605 R together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP--glucose-1-phosphate uridylyltransferase subunit GalU complement(1767697..1768605) Escherichia fergusonii ATCC 35469 7122205 YP_002382861.1 CDS rssB NC_011740.1 1768808 1769869 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339606, 12912910, 9495753; Product type r : regulator; response regulator of RpoS complement(1768808..1769869) Escherichia fergusonii ATCC 35469 7120172 YP_002382862.1 CDS rssA NC_011740.1 1769913 1770851 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein complement(1769913..1770851) Escherichia fergusonii ATCC 35469 7123816 YP_002382863.1 CDS ychJ NC_011740.1 1770932 1771390 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1770932..1771390 Escherichia fergusonii ATCC 35469 7121151 YP_002382864.1 CDS purU NC_011740.1 1771443 1772285 D produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase 1771443..1772285 Escherichia fergusonii ATCC 35469 7123077 YP_002382865.1 CDS EFER_1726 NC_011740.1 1772844 1773935 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8389613; Product type pe : enzyme; Linoleoyl-CoA desaturase complement(1772844..1773935) Escherichia fergusonii ATCC 35469 7121162 YP_002382866.1 CDS EFER_1727 NC_011740.1 1773922 1775046 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1773922..1775046) Escherichia fergusonii ATCC 35469 7120450 YP_002382867.1 CDS EFER_1728 NC_011740.1 1775039 1775653 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; acid phosphatase/vanadium-dependent haloperoxidase complement(1775039..1775653) Escherichia fergusonii ATCC 35469 7124082 YP_002382868.1 CDS EFER_1729 NC_011740.1 1775638 1776972 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1775638..1776972) Escherichia fergusonii ATCC 35469 7122729 YP_002382869.1 CDS EFER_1730 NC_011740.1 1776921 1777727 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1776921..1777727) Escherichia fergusonii ATCC 35469 7122730 YP_002382870.1 CDS EFER_1731 NC_011740.1 1777705 1778721 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1777705..1778721) Escherichia fergusonii ATCC 35469 7122731 YP_002382871.1 CDS EFER_1732 NC_011740.1 1778718 1779725 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; 3-oxoacyl-ACP synthase complement(1778718..1779725) Escherichia fergusonii ATCC 35469 7122732 YP_002382872.1 CDS narI NC_011740.1 1779837 1780514 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 75114694, 89384449, 92121125, 2832376, 3053688; Product type c : carrier; nitrate reductase 1 subunit gamma (cytochrome b(NR)) complement(1779837..1780514) Escherichia fergusonii ATCC 35469 7122733 YP_002382873.1 CDS narJ NC_011740.1 1780514 1781224 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89384449, 92121125, 9632249, 2832376; Product type f : factor; nitrate reductase molybdenum-cofactor-assembly chaperone subunit complement(1780514..1781224) Escherichia fergusonii ATCC 35469 7120677 YP_002382874.1 CDS narH NC_011740.1 1781221 1782759 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 74167294, 89384449, 92121125, 1321049, 2832376, 3053688, 8383531, 8388253, 8664273, 9516445; Product type c : carrier; nitrate reductase 1 subunit, beta (Fe-S) complement(1781221..1782759) Escherichia fergusonii ATCC 35469 7123200 YP_002382875.1 CDS narG NC_011740.1 1782756 1786499 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 74167294, 89384449, 92121125, 2233673, 2668029, 2995309, 3053688, 3308846, 6094247; Product type e : enzyme; nitrate reductase 1 subunit alpha complement(1782756..1786499) Escherichia fergusonii ATCC 35469 7120676 YP_002382876.1 CDS narK NC_011740.1 1786892 1788283 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91258310, 2657652, 2668029; Product type t : transporter; nitrate/nitrite transporter complement(1786892..1788283) Escherichia fergusonii ATCC 35469 7120675 YP_002382877.1 CDS narX NC_011740.1 1788622 1790418 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92276349, 92374842, 94083940, 2649492, 2657652, 2668029; Product type r : regulator; nitrate/nitrite sensor protein NarX 1788622..1790418 Escherichia fergusonii ATCC 35469 7120678 YP_002382878.1 CDS narL NC_011740.1 1790411 1791061 D two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase; transcriptional regulator NarL 1790411..1791061 Escherichia fergusonii ATCC 35469 7120681 YP_002382879.1 CDS ychP NC_011740.1 1791062 1792315 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7567469; Product type pf : factor; hypothetical protein complement(1791062..1792315) Escherichia fergusonii ATCC 35469 7120679 YP_002382880.1 CDS ychN NC_011740.1 1792645 1792998 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1792645..1792998 Escherichia fergusonii ATCC 35469 7123078 YP_002382881.1 CDS chaC NC_011740.1 1793051 1793746 R Evidence 1b : Function experimentally demonstrated in the studied species; Product type r : regulator; regulatory protein for cation transport complement(1793051..1793746) Escherichia fergusonii ATCC 35469 7119940 YP_002382882.1 CDS chaB NC_011740.1 1793904 1794134 R in Escherichia coli this protein putatively regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions; cation transport regulator complement(1793904..1794134) Escherichia fergusonii ATCC 35469 7123234 YP_002382883.1 CDS chaA NC_011740.1 1794405 1795505 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93266586, 94193576, 94292460; Product type t : transporter; calcium/sodium:proton antiporter 1794405..1795505 Escherichia fergusonii ATCC 35469 7123233 YP_002382884.1 CDS EFER_1745 NC_011740.1 1795540 1795926 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1795540..1795926) Escherichia fergusonii ATCC 35469 7120879 YP_002382885.1 CDS kdsA NC_011740.1 1796155 1797009 R catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase complement(1796155..1797009) Escherichia fergusonii ATCC 35469 7122734 YP_002382886.1 CDS ychA NC_011740.1 1797045 1797854 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10322010; Product type pr : regulator; transcriptional regulator complement(1797045..1797854) Escherichia fergusonii ATCC 35469 7120808 YP_002382887.1 CDS EFER_1748 NC_011740.1 1797932 1798009 R hypothetical protein complement(1797932..1798009) Escherichia fergusonii ATCC 35469 7119936 YP_002382888.1 CDS prmC NC_011740.1 1798061 1798891 R HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase complement(1798061..1798891) Escherichia fergusonii ATCC 35469 7122735 YP_002382889.1 CDS prfA NC_011740.1 1798891 1799973 R recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 complement(1798891..1799973) Escherichia fergusonii ATCC 35469 7120131 YP_002382890.1 CDS hemA NC_011740.1 1800015 1801271 R catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase complement(1800015..1801271) Escherichia fergusonii ATCC 35469 7120123 YP_002382891.1 CDS lolB NC_011740.1 1801485 1802108 D Incorporates lipoproteins in the outer membrane after they are released by the LolA protein; outer membrane lipoprotein LolB 1801485..1802108 Escherichia fergusonii ATCC 35469 7123727 YP_002382892.1 CDS ipk NC_011740.1 1802108 1802959 D An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 1802108..1802959 Escherichia fergusonii ATCC 35469 7120844 YP_002382893.1 CDS prsA NC_011740.1 1803110 1804057 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1803110..1804057 Escherichia fergusonii ATCC 35469 7120793 YP_002382894.1 CDS ychM NC_011740.1 1804182 1805879 D role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport; sulfate transporter YchM 1804182..1805879 Escherichia fergusonii ATCC 35469 7119715 YP_002382895.1 CDS ychH NC_011740.1 1805936 1806214 R YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function; hypothetical protein complement(1805936..1806214) Escherichia fergusonii ATCC 35469 7119939 YP_002382896.1 CDS pth NC_011740.1 1806488 1807072 D Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1806488..1807072 Escherichia fergusonii ATCC 35469 7119938 YP_002382897.1 CDS ychF NC_011740.1 1807189 1808280 D translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 1807189..1808280 Escherichia fergusonii ATCC 35469 7122312 YP_002382898.1 CDS treA NC_011740.1 1808434 1810179 D periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell; trehalase 1808434..1810179 Escherichia fergusonii ATCC 35469 7119937 YP_002382899.1 CDS ymgE NC_011740.1 1810217 1810471 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; inner membrane protein with transglycosylase-associated domain complement(1810217..1810471) Escherichia fergusonii ATCC 35469 7122153 YP_002382900.1 CDS ycgR NC_011740.1 1810819 1811553 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; regulator 1810819..1811553 Escherichia fergusonii ATCC 35469 7121690 YP_002382901.1 CDS emtA NC_011740.1 1811565 1812176 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98317285; Product type e : enzyme; lytic murein endotransglycosylase E complement(1811565..1812176) Escherichia fergusonii ATCC 35469 7119935 YP_002382902.1 CDS ldcA NC_011740.1 1812275 1813189 D catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine; L,D-carboxypeptidase A 1812275..1813189 Escherichia fergusonii ATCC 35469 7123560 YP_002382903.1 CDS cvrA NC_011740.1 1813286 1815019 D the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli; potassium/proton antiporter 1813286..1815019 Escherichia fergusonii ATCC 35469 7123227 YP_002382904.1 CDS dadX NC_011740.1 1815068 1816138 R catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA; alanine racemase complement(1815068..1816138) Escherichia fergusonii ATCC 35469 7122835 YP_002382905.1 CDS dadA NC_011740.1 1816150 1817448 R catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit complement(1816150..1817448) Escherichia fergusonii ATCC 35469 7122863 YP_002382906.1 CDS ycgB NC_011740.1 1817770 1819302 D Evidence 4 : Homologs of previously reported genes of unknown function; SpoVR family protein 1817770..1819302 Escherichia fergusonii ATCC 35469 7124116 YP_002382907.1 CDS fadR NC_011740.1 1819369 1820088 R Multifunctional regulator of fatty acid metabolism; fatty acid metabolism regulator complement(1819369..1820088) Escherichia fergusonii ATCC 35469 7119930 YP_002382908.1 CDS nhaB NC_011740.1 1820310 1821854 D involved in regulation of intracellular pH under alkaline conditions; sodium/proton antiporter 1820310..1821854 Escherichia fergusonii ATCC 35469 7119989 YP_002382909.1 CDS dsbB NC_011740.1 1821996 1822526 D disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein; disulfide bond formation protein B 1821996..1822526 Escherichia fergusonii ATCC 35469 7120691 YP_002382910.1 CDS eaeH NC_011740.1 1822591 1826148 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; attaching and effacing protein, pathogenesis factor complement(1822591..1826148) Escherichia fergusonii ATCC 35469 7124127 YP_002382911.1 CDS EFER_1772 NC_011740.1 1826363 1826548 R hypothetical protein complement(1826363..1826548) Escherichia fergusonii ATCC 35469 7122931 YP_002382912.1 CDS ycgN NC_011740.1 1826615 1827061 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1826615..1827061) Escherichia fergusonii ATCC 35469 7124095 YP_002382913.1 CDS ycgM NC_011740.1 1827164 1827823 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15551868; Product type pe : enzyme; hypothetical protein complement(1827164..1827823) Escherichia fergusonii ATCC 35469 7119934 YP_002382914.1 CDS ycgL NC_011740.1 1827874 1828167 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1827874..1828167) Escherichia fergusonii ATCC 35469 7119933 YP_002382915.1 CDS minC NC_011740.1 1828277 1828999 D blocks the formation of polar Z-ring septums; septum formation inhibitor 1828277..1828999 Escherichia fergusonii ATCC 35469 7119932 YP_002382916.1 CDS minD NC_011740.1 1829023 1829835 D ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; cell division inhibitor MinD 1829023..1829835 Escherichia fergusonii ATCC 35469 7123244 YP_002382917.1 CDS minE NC_011740.1 1829839 1830105 D works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 1829839..1830105 Escherichia fergusonii ATCC 35469 7120933 YP_002382918.1 CDS EFER_1779 NC_011740.1 1830477 1831085 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ATPase of ABC-type transport system complement(1830477..1831085) Escherichia fergusonii ATCC 35469 7123640 YP_002382919.1 CDS EFER_1780 NC_011740.1 1831078 1831851 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ATPase of ABC-type transport system complement(1831078..1831851) Escherichia fergusonii ATCC 35469 7122736 YP_002382920.1 CDS EFER_1781 NC_011740.1 1831845 1832675 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; inner membrane transport protein complement(1831845..1832675) Escherichia fergusonii ATCC 35469 7122737 YP_002382921.1 CDS EFER_1782 NC_011740.1 1832647 1833636 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; inner membrane nickel transport protein complement(1832647..1833636) Escherichia fergusonii ATCC 35469 7124096 YP_002382922.1 CDS EFER_1783 NC_011740.1 1833621 1835207 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; substrate-binding transport protein complement(1833621..1835207) Escherichia fergusonii ATCC 35469 7122738 YP_002382923.1 CDS ymgF NC_011740.1 1835341 1835601 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1835341..1835601) Escherichia fergusonii ATCC 35469 7122739 YP_002382924.1 CDS EFER_1785 NC_011740.1 1835772 1838510 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1835772..1838510) Escherichia fergusonii ATCC 35469 7121691 YP_002382925.1 CDS EFER_1786 NC_011740.1 1838898 1840199 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7559343, 1597179; Product type pe : enzyme; Thermostable carboxypeptidase 1 complement(1838898..1840199) Escherichia fergusonii ATCC 35469 7122740 YP_002382926.1 CDS ycgK NC_011740.1 1840567 1840968 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1840567..1840968 Escherichia fergusonii ATCC 35469 7122741 YP_002382927.1 CDS yeeN NC_011740.1 1841064 1841780 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1841064..1841780) Escherichia fergusonii ATCC 35469 7119931 YP_002382928.1 CDS EFER_1789 NC_011740.1 1842244 1842534 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1842244..1842534 Escherichia fergusonii ATCC 35469 7121547 YP_002382929.1 CDS EFER_1790 NC_011740.1 1842932 1846201 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15659678; Product type pf : factor; adhesin yeeJ (fragment) 1842932..1846201 Escherichia fergusonii ATCC 35469 7122742 YP_002382930.1 CDS EFER_1791 NC_011740.1 1846554 1847036 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; glutathione S-transferase 1846554..1847036 Escherichia fergusonii ATCC 35469 7122743 YP_002382931.1 CDS EFER_1792 NC_011740.1 1847374 1848201 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1847374..1848201) Escherichia fergusonii ATCC 35469 7122744 YP_002382932.1 CDS icd NC_011740.1 1848968 1850218 R Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase complement(1848968..1850218) Escherichia fergusonii ATCC 35469 7120749 YP_002382933.1 CDS ymfC NC_011740.1 1850390 1851043 D catalyzes the formation of pseudouridine from uracil-2457 in 23S ribosomal RNA; 23S rRNA pseudouridine synthase E 1850390..1851043 Escherichia fergusonii ATCC 35469 7123741 YP_002382934.1 CDS ymfB NC_011740.1 1851053 1851514 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15292217; Product type e : enzyme; bifunctional thiamin pyrimidine pyrophosphate hydrolase/thiamin pyrophosphate hydrolase 1851053..1851514 Escherichia fergusonii ATCC 35469 7122055 YP_002382935.1 CDS mnmA NC_011740.1 1851568 1852674 D catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1851568..1852674 Escherichia fergusonii ATCC 35469 7123419 YP_002382936.1 CDS hflD NC_011740.1 1852710 1853351 D HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein 1852710..1853351 Escherichia fergusonii ATCC 35469 7123990 YP_002382937.1 CDS purB NC_011740.1 1853355 1854725 D Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 1853355..1854725 Escherichia fergusonii ATCC 35469 7122189 YP_002382938.1 CDS phoP NC_011740.1 1854891 1855562 D response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress; DNA-binding transcriptional regulator PhoP 1854891..1855562 Escherichia fergusonii ATCC 35469 7124021 YP_002382939.1 CDS phoQ NC_011740.1 1855562 1857022 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92105017; Product type r : regulator; sensor protein PhoQ 1855562..1857022 Escherichia fergusonii ATCC 35469 7122601 YP_002382940.1 CDS ycfD NC_011740.1 1857112 1858233 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1857112..1858233 Escherichia fergusonii ATCC 35469 7122602 YP_002382941.1 CDS yeaE NC_011740.1 1858282 1859181 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; oxidoreductase complement(1858282..1859181) Escherichia fergusonii ATCC 35469 7123074 YP_002382942.1 CDS mipA NC_011740.1 1859226 1859972 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10037771, 20267815; Product type f : factor; scaffolding protein for murein synthesizing machinery complement(1859226..1859972) Escherichia fergusonii ATCC 35469 7121443 YP_002382943.1 CDS yeaG NC_011740.1 1860408 1862342 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1860408..1862342 Escherichia fergusonii ATCC 35469 7120936 YP_002382944.1 CDS yeaH NC_011740.1 1862455 1863738 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1862455..1863738 Escherichia fergusonii ATCC 35469 7123331 YP_002382945.1 CDS yeaI NC_011740.1 1864017 1865363 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15919996; Product type m : membrane component; Inner membrane protein yeaI 1864017..1865363 Escherichia fergusonii ATCC 35469 7121506 YP_002382946.1 CDS yeaJ NC_011740.1 1865534 1867036 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 1865534..1867036 Escherichia fergusonii ATCC 35469 7121507 YP_002382947.1 CDS yeaK NC_011740.1 1867079 1867630 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1867079..1867630 Escherichia fergusonii ATCC 35469 7121508 YP_002382948.1 CDS yeaL NC_011740.1 1867899 1868345 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1867899..1868345 Escherichia fergusonii ATCC 35469 7122745 YP_002382949.1 CDS yeaN NC_011740.1 1868453 1869640 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; MFS superfamily transporter 1868453..1869640 Escherichia fergusonii ATCC 35469 7123879 YP_002382950.1 CDS yeaO NC_011740.1 1869695 1870042 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1869695..1870042 Escherichia fergusonii ATCC 35469 7121510 YP_002382951.1 CDS yoaF NC_011740.1 1870061 1870318 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1870061..1870318) Escherichia fergusonii ATCC 35469 7123880 YP_002382952.1 CDS yeaP NC_011740.1 1870514 1871554 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1870514..1871554 Escherichia fergusonii ATCC 35469 7121724 YP_002382953.1 CDS yeaQ NC_011740.1 1871813 1872061 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(1871813..1872061) Escherichia fergusonii ATCC 35469 7123881 YP_002382954.1 CDS yeaS NC_011740.1 1872227 1872919 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; leucine export protein LeuE complement(1872227..1872919) Escherichia fergusonii ATCC 35469 7121511 YP_002382955.1 CDS ycfJ NC_011740.1 1873068 1873607 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 6265208, 7984428; hypothetical protein complement(1873068..1873607) Escherichia fergusonii ATCC 35469 7121512 YP_002382956.1 CDS ndh NC_011740.1 1873777 1875081 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14766919, 20130027, 81256452, 92296775, 94042945, 99441207, 6265208; Product type e : enzyme; respiratory NADH dehydrogenase 2/cupric reductase complement(1873777..1875081) Escherichia fergusonii ATCC 35469 7119925 YP_002382957.1 CDS ycfP NC_011740.1 1875322 1875864 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1875322..1875864) Escherichia fergusonii ATCC 35469 7120682 YP_002382958.1 CDS nagZ NC_011740.1 1875888 1876913 R hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides; beta-hexosaminidase complement(1875888..1876913) Escherichia fergusonii ATCC 35469 7119927 YP_002382959.1 CDS thiK NC_011740.1 1876935 1877747 R catalyzes the phosphorylation of thiamine to thiamine phosphate; thiamine kinase complement(1876935..1877747) Escherichia fergusonii ATCC 35469 7120664 YP_002382960.1 CDS ycfM NC_011740.1 1877728 1878369 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; outer membrane lipoprotein complement(1877728..1878369) Escherichia fergusonii ATCC 35469 7121995 YP_002382961.1 CDS ycfL NC_011740.1 1878383 1878757 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1878383..1878757) Escherichia fergusonii ATCC 35469 7119926 YP_002382962.1 CDS hinT NC_011740.1 1878760 1879119 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15703176, 10493123, 2162465; Product type e : enzyme; purine nucleoside phosphoramidase complement(1878760..1879119) Escherichia fergusonii ATCC 35469 7123075 YP_002382963.1 CDS ptsG NC_011740.1 1879455 1880888 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucose-specific transporter subunit IIBC complement(1879455..1880888) Escherichia fergusonii ATCC 35469 7122194 YP_002382964.1 CDS ycfH NC_011740.1 1881182 1881979 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8505303, 8509334, 10747959; Product type pe : enzyme; metallodependent hydrolase complement(1881182..1881979) Escherichia fergusonii ATCC 35469 7124020 YP_002382965.1 CDS holB NC_011740.1 1881990 1882994 R catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' complement(1881990..1882994) Escherichia fergusonii ATCC 35469 7119924 YP_002382966.1 CDS tmk NC_011740.1 1882991 1883632 R catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase complement(1882991..1883632) Escherichia fergusonii ATCC 35469 7122209 YP_002382967.1 CDS yceG NC_011740.1 1883622 1884644 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein complement(1883622..1884644) Escherichia fergusonii ATCC 35469 7122136 YP_002382968.1 CDS pabC NC_011740.1 1884641 1885456 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1644759, 2071583, 2251281, 10876155; Product type e : enzyme; Aminodeoxychorismate lyase complement(1884641..1885456) Escherichia fergusonii ATCC 35469 7119920 YP_002382969.1 CDS fabF NC_011740.1 1885574 1886815 R FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II complement(1885574..1886815) Escherichia fergusonii ATCC 35469 7123497 YP_002382970.1 CDS acpP NC_011740.1 1886904 1887140 R carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein complement(1886904..1887140) Escherichia fergusonii ATCC 35469 7119981 YP_002382971.1 CDS fabG NC_011740.1 1887416 1888150 R catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(1887416..1888150) Escherichia fergusonii ATCC 35469 7122263 YP_002382972.1 CDS fabD NC_011740.1 1888162 1889091 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92052166, 92183950, 92210530, 92234941, 7700236, 7768883, 9298646; Product type e : enzyme; malonyl-CoA-[acyl-carrier-protein] transacylase complement(1888162..1889091) Escherichia fergusonii ATCC 35469 7119982 YP_002382973.1 CDS fabH NC_011740.1 1889107 1890060 R FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase complement(1889107..1890060) Escherichia fergusonii ATCC 35469 7119980 YP_002382974.1 CDS plsX NC_011740.1 1890136 1891212 R involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX complement(1890136..1891212) Escherichia fergusonii ATCC 35469 7119983 YP_002382975.1 CDS rpmF NC_011740.1 1891293 1891466 R some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 complement(1891293..1891466) Escherichia fergusonii ATCC 35469 7120089 YP_002382976.1 CDS yceD NC_011740.1 1891518 1892039 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 90008815, 1447160; hypothetical protein complement(1891518..1892039) Escherichia fergusonii ATCC 35469 7121117 YP_002382977.1 CDS yceF NC_011740.1 1892198 1892821 D Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 1892198..1892821 Escherichia fergusonii ATCC 35469 7123439 YP_002382978.1 CDS rluC NC_011740.1 1892930 1893925 R catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA; 23S rRNA pseudouridylate synthase C complement(1892930..1893925) Escherichia fergusonii ATCC 35469 7119919 YP_002382979.1 CDS rne NC_011740.1 1894457 1897636 D bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase; ribonuclease E 1894457..1897636 Escherichia fergusonii ATCC 35469 7121418 YP_002382980.1 CDS flgL NC_011740.1 1897784 1898737 R with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes; flagellar hook-associated protein FlgL complement(1897784..1898737) Escherichia fergusonii ATCC 35469 7121425 YP_002382981.1 CDS flgK NC_011740.1 1898753 1900399 R with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK complement(1898753..1900399) Escherichia fergusonii ATCC 35469 7122977 YP_002382982.1 CDS flgJ NC_011740.1 1900465 1901406 R Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space; flagellar rod assembly protein/muramidase FlgJ complement(1900465..1901406) Escherichia fergusonii ATCC 35469 7122976 YP_002382983.1 CDS flgI NC_011740.1 1901406 1902503 R part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein complement(1901406..1902503) Escherichia fergusonii ATCC 35469 7122975 YP_002382984.1 CDS flgH NC_011740.1 1902515 1903213 R part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein complement(1902515..1903213) Escherichia fergusonii ATCC 35469 7122974 YP_002382985.1 CDS flgG NC_011740.1 1903266 1904048 R makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG complement(1903266..1904048) Escherichia fergusonii ATCC 35469 7122973 YP_002382986.1 CDS flgF NC_011740.1 1904200 1904955 R FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF complement(1904200..1904955) Escherichia fergusonii ATCC 35469 7122972 YP_002382987.1 CDS flgE NC_011740.1 1904975 1906180 R the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE complement(1904975..1906180) Escherichia fergusonii ATCC 35469 7122971 YP_002382988.1 CDS flgD NC_011740.1 1906205 1906900 R acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production; flagellar basal body rod modification protein complement(1906205..1906900) Escherichia fergusonii ATCC 35469 7123563 YP_002382989.1 CDS flgC NC_011740.1 1906912 1907316 R with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC complement(1906912..1907316) Escherichia fergusonii ATCC 35469 7122970 YP_002382990.1 CDS flgB NC_011740.1 1907320 1907811 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1482109, 89181349; Product type s : structure; flagellar basal-body rod cell-proximal protein complement(1907320..1907811) Escherichia fergusonii ATCC 35469 7122969 YP_002382991.1 CDS flgA NC_011740.1 1907842 1908552 D required for the assembly of the flagellar basal body P-ring; flagellar basal body P-ring biosynthesis protein FlgA 1907842..1908552 Escherichia fergusonii ATCC 35469 7122968 YP_002382992.1 CDS flgM NC_011740.1 1908643 1908936 D regulates the flagellar specific sigma28 transcription factor; anti-sigma-28 factor FlgM 1908643..1908936 Escherichia fergusonii ATCC 35469 7122967 YP_002382993.1 CDS flgN NC_011740.1 1908941 1909363 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1655712, 8200538; Product type f : factor; Flagella synthesis protein flgN 1908941..1909363 Escherichia fergusonii ATCC 35469 7124136 YP_002382994.1 CDS mviN NC_011740.1 1909401 1910978 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(1909401..1910978) Escherichia fergusonii ATCC 35469 7124137 YP_002382995.1 CDS mviM NC_011740.1 1911049 1911972 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; oxidoreductase complement(1911049..1911972) Escherichia fergusonii ATCC 35469 7123730 YP_002382996.1 CDS yceH NC_011740.1 1911974 1912648 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1356970, 2828880; hypothetical protein complement(1911974..1912648) Escherichia fergusonii ATCC 35469 7120655 YP_002382997.1 CDS rimJ NC_011740.1 1912630 1913244 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88121676, 90136529, 1356970; Product type e : enzyme; ribosomal-protein-S5-alanine N-acetyltransferase complement(1912630..1913244) Escherichia fergusonii ATCC 35469 7119921 YP_002382998.1 CDS mdtH NC_011740.1 1913380 1914666 D Confers resistance to norfloxacin and enoxacin; multidrug resistance protein MdtH 1913380..1914666 Escherichia fergusonii ATCC 35469 7121412 YP_002382999.1 CDS yceB NC_011740.1 1914811 1915371 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; hypothetical protein 1914811..1915371 Escherichia fergusonii ATCC 35469 7121253 YP_002383000.1 CDS pyrC NC_011740.1 1915476 1916522 D catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 1915476..1916522 Escherichia fergusonii ATCC 35469 7119917 YP_002383001.2 CDS dinI NC_011740.1 1916595 1916840 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9606202, 11152126, 11230150, 8682790; Product type f : factor; DNA damage-inducible protein I 1916595..1916840 Escherichia fergusonii ATCC 35469 7123464 YP_002383002.1 CDS bssS NC_011740.1 1917129 1917383 D BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing; biofilm formation regulatory protein BssS 1917129..1917383 Escherichia fergusonii ATCC 35469 7122900 YP_002383003.1 CDS solA NC_011740.1 1917500 1918615 D catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids; N-methyltryptophan oxidase 1917500..1918615 Escherichia fergusonii ATCC 35469 7121679 YP_002383004.1 CDS yceJ NC_011740.1 1918989 1919567 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; cytochrome b561 1918989..1919567 Escherichia fergusonii ATCC 35469 7121800 YP_002383005.1 CDS yceI NC_011740.1 1919564 1920139 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15741337, 11298273, 1840644, 9298646; Product type c : carrier; hypothetical protein 1919564..1920139 Escherichia fergusonii ATCC 35469 7119922 YP_002383006.1 CDS yceA NC_011740.1 1920189 1921241 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1840644; hypothetical protein complement(1920189..1921241) Escherichia fergusonii ATCC 35469 7123073 YP_002383007.1 CDS lpxL NC_011740.1 1921462 1922382 D Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 1921462..1922382 Escherichia fergusonii ATCC 35469 7119916 YP_002383008.1 CDS mdtG NC_011740.1 1922565 1923791 D Confers resistance to fosfomycin and deoxycholate; drug efflux system protein MdtG 1922565..1923791 Escherichia fergusonii ATCC 35469 7121203 YP_002383009.1 CDS msyB NC_011740.1 1923874 1924248 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 92165719; hypothetical protein 1923874..1924248 Escherichia fergusonii ATCC 35469 7123290 YP_002383010.1 CDS yceK NC_011740.1 1924249 1924476 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; hypothetical protein complement(1924249..1924476) Escherichia fergusonii ATCC 35469 7120975 YP_002383011.1 CDS mdoH NC_011740.1 1924629 1927172 R necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space; glucosyltransferase MdoH complement(1924629..1927172) Escherichia fergusonii ATCC 35469 7119923 YP_002383012.1 CDS mdoG NC_011740.1 1927165 1928700 R involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan; glucan biosynthesis protein G complement(1927165..1928700) Escherichia fergusonii ATCC 35469 7121246 YP_002383013.1 CDS EFER_1880 NC_011740.1 1928744 1928902 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1928744..1928902 Escherichia fergusonii ATCC 35469 7121245 YP_002383014.1 CDS mdoC NC_011740.1 1928974 1930134 D required for the transfer of succinyl residues to the glucan backbone; glucans biosynthesis protein 1928974..1930134 Escherichia fergusonii ATCC 35469 7122746 YP_002383015.1 CDS ymdC NC_011740.1 1930142 1931632 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hydrolase complement(1930142..1931632) Escherichia fergusonii ATCC 35469 7121244 YP_002383016.1 CDS ymdB NC_011740.1 1931565 1932113 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1931565..1932113) Escherichia fergusonii ATCC 35469 7122054 YP_002383017.1 CDS ymdA NC_011740.1 1932193 1932507 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1932193..1932507) Escherichia fergusonii ATCC 35469 7123417 YP_002383018.1 CDS csgC NC_011740.1 1932623 1932955 R involved in autoagglutination of curliated cells; not involved in production of curli fibers; autoagglutination protein complement(1932623..1932955) Escherichia fergusonii ATCC 35469 7122053 YP_002383019.1 CDS csgA NC_011740.1 1933015 1933473 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89201357, 93023873, 1677357, 8459772, 8817489, 1357528; Product type s : structure; cryptic curlin major subunit complement(1933015..1933473) Escherichia fergusonii ATCC 35469 7122812 YP_002383020.1 CDS csgB NC_011740.1 1933514 1933990 R CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface; curlin minor subunit complement(1933514..1933990) Escherichia fergusonii ATCC 35469 7124106 YP_002383021.1 CDS csgD NC_011740.1 1934710 1935360 D activates the csgBA and csgDEFG operons involved in biofilm formation; DNA-binding transcriptional regulator CsgD 1934710..1935360 Escherichia fergusonii ATCC 35469 7122811 YP_002383022.1 CDS csgE NC_011740.1 1935230 1935754 D chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgE 1935230..1935754 Escherichia fergusonii ATCC 35469 7124107 YP_002383023.1 CDS csgF NC_011740.1 1935778 1936194 D nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex; curli assembly protein CsgF 1935778..1936194 Escherichia fergusonii ATCC 35469 7122813 YP_002383024.1 CDS csgG NC_011740.1 1936221 1937054 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8817489; Product type lp : lipoprotein; outer membrane lipoprotein 1936221..1937054 Escherichia fergusonii ATCC 35469 7122814 YP_002383025.1 CDS ycdZ NC_011740.1 1937092 1937583 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(1937092..1937583) Escherichia fergusonii ATCC 35469 7124108 YP_002383026.1 CDS ycdY NC_011740.1 1937675 1938229 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1937675..1938229) Escherichia fergusonii ATCC 35469 7119915 YP_002383027.1 CDS ycdX NC_011740.1 1938253 1938990 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12661000; Product type pe : enzyme; hydrolase complement(1938253..1938990) Escherichia fergusonii ATCC 35469 7123613 YP_002383028.1 CDS ycdW NC_011740.1 1939077 1940015 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11237876, 10493123; Product type e : enzyme; 2-ketoacid reductase complement(1939077..1940015) Escherichia fergusonii ATCC 35469 7119914 YP_002383029.1 CDS lysU NC_011740.1 1940790 1942307 R class II; inducible; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; induced by high temperature, anaerobiosis, and low pH; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(1940790..1942307) Escherichia fergusonii ATCC 35469 7120034 YP_002383030.1 CDS yjdL NC_011740.1 1942576 1944033 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter complement(1942576..1944033) Escherichia fergusonii ATCC 35469 7123829 YP_002383031.1 CDS cadA NC_011740.1 1944092 1946239 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92105022, 92210511, 1370290, 1556085, 4204273; Product type e : enzyme; lysine decarboxylase 1 complement(1944092..1946239) Escherichia fergusonii ATCC 35469 7122005 YP_002383032.1 CDS cadB NC_011740.1 1946319 1947653 R antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein; lysine/cadaverine antiporter complement(1946319..1947653) Escherichia fergusonii ATCC 35469 7121686 YP_002383033.1 CDS cadC NC_011740.1 1948017 1949546 R regulates the cadBA operon; DNA-binding transcriptional activator CadC complement(1948017..1949546) Escherichia fergusonii ATCC 35469 7121687 YP_002383034.1 CDS ycdT NC_011740.1 1949886 1951277 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16530465, 17322315; Product type pe : enzyme; diguanylate cyclase, GGDEF protein complement(1949886..1951277) Escherichia fergusonii ATCC 35469 7123908 YP_002383035.1 CDS pgaA NC_011740.1 1951826 1954249 D outer membrane protein essential for the synthesis of poly-beta-1,6-N-acetyl-D-glucosamine (PGA); adhesin required for biofilm formation; PgaA (HmsH) seems to translocate and/or dock PGA to the cell surface; member of the hmsHFRS (ycdSRQP or pgaABCD in Escherichia coli) operon in Yersinia; outer membrane protein PgaA 1951826..1954249 Escherichia fergusonii ATCC 35469 7123612 YP_002383036.1 CDS pgaB NC_011740.1 1954258 1956276 D in Yersinia this protein is involved in biofilm formation and hemin adsorption; related protein PgaB in Escherichia coli is an outer membrane N-deacetylase involved in poly-beta-1,6-N-acetyl-D-glucosamine (PGA) export; outer membrane N-deacetylase 1954258..1956276 Escherichia fergusonii ATCC 35469 7122586 YP_002383037.1 CDS pgaC NC_011740.1 1956269 1957594 D predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein; N-glycosyltransferase 1956269..1957594 Escherichia fergusonii ATCC 35469 7124066 YP_002383038.1 CDS pgaD NC_011740.1 1957596 1958009 D in Yersinia this gene is involved in biofilm formation and hemin adsorption; in Escherichia coli it is involved in PGA biosynthesis and export; PGA biosynthesis protein 1957596..1958009 Escherichia fergusonii ATCC 35469 7124067 YP_002383039.1 CDS phoH NC_011740.1 1958050 1958973 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8444794, 2160940; Product type pe : enzyme; hypothetical protein complement(1958050..1958973) Escherichia fergusonii ATCC 35469 7119912 YP_002383040.1 CDS efeB NC_011740.1 1959446 1960717 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 17627767, 16551627, 15375152; Product type t : transporter; iron transport heme-binding periplasmic protein complement(1959446..1960717) Escherichia fergusonii ATCC 35469 7122600 YP_002383041.1 CDS efeO NC_011740.1 1960723 1961850 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 17627767, 10493123; Product type t : transporter; hypothetical protein complement(1960723..1961850) Escherichia fergusonii ATCC 35469 7124132 YP_002383042.1 CDS efeU NC_011740.1 1961908 1962747 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; ferrous iron permease complement(1961908..1962747) Escherichia fergusonii ATCC 35469 7122938 YP_002383043.1 CDS putP NC_011740.1 1962958 1964466 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12923181, 88213396, 91227628, 93132799, 98359785, 1400239, 1567896, 3053649, 3053687, 3302614, 3325781, 8119910; Product type t : transporter; proline:sodium symporter complement(1962958..1964466) Escherichia fergusonii ATCC 35469 7122939 YP_002383044.1 CDS putA NC_011740.1 1964889 1968851 D proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein; multifunctional functional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 1964889..1968851 Escherichia fergusonii ATCC 35469 7122331 YP_002383045.1 CDS msbB NC_011740.1 1968944 1969885 R Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase complement(1968944..1969885) Escherichia fergusonii ATCC 35469 7122330 YP_002383046.1 CDS virK NC_011740.1 1969962 1970867 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1406277; Product type r : regulator; VirG localization protein VirK complement(1969962..1970867) Escherichia fergusonii ATCC 35469 7120971 YP_002383047.1 CDS EFER_1916 NC_011740.1 1970913 1972001 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; glycosyl transferase family protein complement(1970913..1972001) Escherichia fergusonii ATCC 35469 7122657 YP_002383048.1 CDS EFER_1917 NC_011740.1 1972054 1972197 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1972054..1972197) Escherichia fergusonii ATCC 35469 7122747 YP_002383049.1 CDS shf NC_011740.1 1972226 1973044 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; carbohydrate transport protein complement(1972226..1973044) Escherichia fergusonii ATCC 35469 7122748 YP_002383050.1 CDS umuC NC_011740.1 1973225 1974493 R binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuC complement(1973225..1974493) Escherichia fergusonii ATCC 35469 7121781 YP_002383051.1 CDS umuD NC_011740.1 1974493 1974912 R binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuD complement(1974493..1974912) Escherichia fergusonii ATCC 35469 7122637 YP_002383052.1 CDS fliE NC_011740.1 1975170 1975484 R forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body protein FliE complement(1975170..1975484) Escherichia fergusonii ATCC 35469 7122638 YP_002383053.1 CDS EFER_1922 NC_011740.1 1975529 1975678 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1975529..1975678) Escherichia fergusonii ATCC 35469 7122984 YP_002383054.1 CDS fliF NC_011740.1 1975699 1977357 D the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 1975699..1977357 Escherichia fergusonii ATCC 35469 7122749 YP_002383055.1 CDS fliG NC_011740.1 1977350 1978345 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein G 1977350..1978345 Escherichia fergusonii ATCC 35469 7122985 YP_002383056.1 CDS fliH NC_011740.1 1978338 1979024 D binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein H 1978338..1979024 Escherichia fergusonii ATCC 35469 7123565 YP_002383057.1 CDS fliI NC_011740.1 1979021 1980394 D involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 1979021..1980394 Escherichia fergusonii ATCC 35469 7123566 YP_002383058.1 CDS fliJ NC_011740.1 1980416 1980859 D rod/hook and filament chaperone; flagellar biosynthesis chaperone 1980416..1980859 Escherichia fergusonii ATCC 35469 7122986 YP_002383059.1 CDS fliK NC_011740.1 1980856 1982004 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8631687; Product type s : structure; flagellar hook-length control protein 1980856..1982004 Escherichia fergusonii ATCC 35469 7122987 YP_002383060.1 CDS fliL NC_011740.1 1982109 1982567 D interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar basal body-associated protein FliL 1982109..1982567 Escherichia fergusonii ATCC 35469 7122988 YP_002383061.1 CDS fliM NC_011740.1 1982572 1983576 D with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 1982572..1983576 Escherichia fergusonii ATCC 35469 7122989 YP_002383062.1 CDS fliN NC_011740.1 1983573 1983986 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliN 1983573..1983986 Escherichia fergusonii ATCC 35469 7122990 YP_002383063.1 CDS fliO NC_011740.1 1983988 1984350 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8282695; Product type s : structure; Flagellar protein fliO 1983988..1984350 Escherichia fergusonii ATCC 35469 7122991 YP_002383064.1 CDS fliP NC_011740.1 1984350 1985087 D FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 1984350..1985087 Escherichia fergusonii ATCC 35469 7122992 YP_002383065.1 CDS fliQ NC_011740.1 1985096 1985365 D with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliQ 1985096..1985365 Escherichia fergusonii ATCC 35469 7124139 YP_002383066.1 CDS fliR NC_011740.1 1985358 1986161 D FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 1985358..1986161 Escherichia fergusonii ATCC 35469 7122993 YP_002383067.1 CDS rcsA NC_011740.1 1986438 1987061 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14514676, 14766922, 20167175, 90130299, 91154130, 92048476, 9882673, 7534408; Product type r : regulator; DNA-binding transcriptional activator 1986438..1987061 Escherichia fergusonii ATCC 35469 7122994 YP_002383068.1 CDS dsrB NC_011740.1 1987109 1987297 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 96324407, 7534408; hypothetical protein complement(1987109..1987297) Escherichia fergusonii ATCC 35469 7124027 YP_002383069.1 CDS yodD NC_011740.1 1987449 1987676 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 1987449..1987676 Escherichia fergusonii ATCC 35469 7122927 YP_002383070.1 CDS EFER_1939 NC_011740.1 1987844 1988791 D catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate; mannosyl-3-phosphoglycerate phosphatase 1987844..1988791 Escherichia fergusonii ATCC 35469 7122925 YP_002383071.1 CDS EFER_1940 NC_011740.1 1988764 1990476 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; diguanylate cyclase; GGDEF domain; PLP-dependent transferase complement(1988764..1990476) Escherichia fergusonii ATCC 35469 7122750 YP_002383072.1 CDS EFER_1941 NC_011740.1 1990596 1990835 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1990596..1990835) Escherichia fergusonii ATCC 35469 7122751 YP_002383073.1 CDS yedI NC_011740.1 1990853 1991764 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(1990853..1991764) Escherichia fergusonii ATCC 35469 7122752 YP_002383074.1 CDS yedA NC_011740.1 1991941 1992861 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 1991941..1992861 Escherichia fergusonii ATCC 35469 7121540 YP_002383075.1 CDS vsr NC_011740.1 1992853 1993326 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90330522, 92049708, 94049122, 10360178, 10612397, 10871403, 2527357; Product type e : enzyme; DNA mismatch endonuclease of very short patch repair complement(1992853..1993326) Escherichia fergusonii ATCC 35469 7121536 YP_002383076.1 CDS EFER_1945 NC_011740.1 1993345 1994034 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(1993345..1994034) Escherichia fergusonii ATCC 35469 7124079 YP_002383077.1 CDS EFER_1947 NC_011740.1 1994087 1994374 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; permease complement(1994087..1994374) Escherichia fergusonii ATCC 35469 7123527 YP_002383078.1 CDS EFER_1948 NC_011740.1 1995018 1996073 D Evidence 2b : Function of strongly homologous gene; Product type m : membrane component; outer membrane protein N 1995018..1996073 Escherichia fergusonii ATCC 35469 7122753 YP_002383079.1 CDS nmpC NC_011740.1 1996644 1997747 D Evidence 2b : Function of strongly homologous gene; PubMedId : 3017988, 8057841; Product type m : membrane component; outer membrane porin; DLP12 prophage 1996644..1997747 Escherichia fergusonii ATCC 35469 7122754 YP_002383080.1 CDS trkG NC_011740.1 1998187 1999662 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type t : transporter; Trk system potassium uptake protein 1998187..1999662 Escherichia fergusonii ATCC 35469 7119653 YP_002383081.1 CDS hchA NC_011740.1 1999771 2000622 D Hsp31 stabilizes early unfolding protein intermediates under severe heat stress; chaperone protein HchA 1999771..2000622 Escherichia fergusonii ATCC 35469 7123435 YP_002383082.1 CDS yeeI NC_011740.1 2001152 2001949 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2001152..2001949 Escherichia fergusonii ATCC 35469 7123098 YP_002383083.1 CDS cbl NC_011740.1 2002164 2003114 R LysR-type transcriptional regulator similar to CysB; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates two operons consisting of ABC transporters that are part of the cys regulon; regulated by CysB; transcriptional regulator Cbl complement(2002164..2003114) Escherichia fergusonii ATCC 35469 7123632 YP_002383084.1 CDS nac NC_011740.1 2003216 2004133 R Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation; nitrogen assimilation transcriptional regulator complement(2003216..2004133) Escherichia fergusonii ATCC 35469 7120861 YP_002383085.1 CDS EFER_1956 NC_011740.1 2004648 2004971 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; phage integrase 2004648..2004971 Escherichia fergusonii ATCC 35469 7123633 YP_002383086.1 CDS EFER_1957 NC_011740.1 2005212 2005358 R Evidence 6 : Doubtful CDS; hypothetical protein complement(2005212..2005358) Escherichia fergusonii ATCC 35469 7123528 YP_002383087.1 CDS EFER_1958 NC_011740.1 2005536 2005895 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2005536..2005895) Escherichia fergusonii ATCC 35469 7122755 YP_002383088.1 CDS EFER_1959 NC_011740.1 2005907 2006371 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; hypothetical protein complement(2005907..2006371) Escherichia fergusonii ATCC 35469 7122756 YP_002383089.1 CDS EFER_1960 NC_011740.1 2007155 2007604 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2007155..2007604) Escherichia fergusonii ATCC 35469 7123529 YP_002383090.1 CDS EFER_1961 NC_011740.1 2007604 2008275 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2007604..2008275) Escherichia fergusonii ATCC 35469 7122757 YP_002383091.1 CDS EFER_1962 NC_011740.1 2008475 2008954 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 16763151; hypothetical protein complement(2008475..2008954) Escherichia fergusonii ATCC 35469 7122758 YP_002383092.1 CDS EFER_1963 NC_011740.1 2008972 2010477 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2008972..2010477) Escherichia fergusonii ATCC 35469 7124097 YP_002383093.1 CDS EFER_1964 NC_011740.1 2010341 2013862 R Evidence 2b : Function of strongly homologous gene; Product type pe : enzyme; IcmF-like protein complement(2010341..2013862) Escherichia fergusonii ATCC 35469 7122759 YP_002383094.1 CDS EFER_1965 NC_011740.1 2013881 2015314 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2013881..2015314) Escherichia fergusonii ATCC 35469 7123530 YP_002383095.1 CDS EFER_1966 NC_011740.1 2015317 2016060 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2015317..2016060) Escherichia fergusonii ATCC 35469 7122760 YP_002383096.1 CDS EFER_1967 NC_011740.1 2016057 2018783 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; ATP-dependent Clp proteinase ATP-binding subunit complement(2016057..2018783) Escherichia fergusonii ATCC 35469 7122761 YP_002383097.1 CDS EFER_1968 NC_011740.1 2018792 2019601 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; membrane protein Aec26 complement(2018792..2019601) Escherichia fergusonii ATCC 35469 7123531 YP_002383098.1 CDS EFER_1969 NC_011740.1 2019594 2021051 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2019594..2021051) Escherichia fergusonii ATCC 35469 7122762 YP_002383099.1 CDS EFER_1970 NC_011740.1 2020952 2021485 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2020952..2021485) Escherichia fergusonii ATCC 35469 7122763 YP_002383100.1 CDS EFER_1971 NC_011740.1 2021482 2022762 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2021482..2022762) Escherichia fergusonii ATCC 35469 7123532 YP_002383101.1 CDS EFER_1972 NC_011740.1 2022786 2023823 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2022786..2023823) Escherichia fergusonii ATCC 35469 7122764 YP_002383102.1 CDS EFER_1973 NC_011740.1 2023787 2025619 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2023787..2025619) Escherichia fergusonii ATCC 35469 7122765 YP_002383103.1 CDS EFER_1974 NC_011740.1 2025625 2026062 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2025625..2026062) Escherichia fergusonii ATCC 35469 7124098 YP_002383104.1 CDS EFER_1975 NC_011740.1 2026065 2027546 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2026065..2027546) Escherichia fergusonii ATCC 35469 7122766 YP_002383105.1 CDS EFER_1976 NC_011740.1 2027561 2028160 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2027561..2028160) Escherichia fergusonii ATCC 35469 7122767 YP_002383106.1 CDS EFER_1977 NC_011740.1 2028690 2029271 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2028690..2029271 Escherichia fergusonii ATCC 35469 7124099 YP_002383107.1 CDS EFER_1978 NC_011740.1 2029481 2031427 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2029481..2031427 Escherichia fergusonii ATCC 35469 7122768 YP_002383108.1 CDS EFER_1979 NC_011740.1 2031449 2031868 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2031449..2031868 Escherichia fergusonii ATCC 35469 7122769 YP_002383109.1 CDS EFER_1980 NC_011740.1 2031895 2036526 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2031895..2036526 Escherichia fergusonii ATCC 35469 7123533 YP_002383110.1 CDS EFER_1981 NC_011740.1 2036533 2036805 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2036533..2036805 Escherichia fergusonii ATCC 35469 7122770 YP_002383111.1 CDS amn NC_011740.1 2037984 2039438 R Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase complement(2037984..2039438) Escherichia fergusonii ATCC 35469 7122671 YP_002383112.1 CDS shiA NC_011740.1 2039566 2040870 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 5332864, 9524262; Product type t : transporter; shikimate transporter complement(2039566..2040870) Escherichia fergusonii ATCC 35469 7122302 YP_002383113.1 CDS yeeO NC_011740.1 2041421 2042857 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16042411; Product type pt : transporter; hypothetical protein complement(2041421..2042857) Escherichia fergusonii ATCC 35469 7120078 YP_002383114.1 CDS EFER_1986 NC_011740.1 2043439 2044017 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2043439..2044017 Escherichia fergusonii ATCC 35469 7120035 YP_002383115.1 CDS EFER_1987 NC_011740.1 2044040 2044858 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2044040..2044858 Escherichia fergusonii ATCC 35469 7124100 YP_002383116.1 CDS EFER_1988 NC_011740.1 2044858 2045376 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2044858..2045376 Escherichia fergusonii ATCC 35469 7122772 YP_002383117.1 CDS EFER_1989 NC_011740.1 2045845 2046174 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10768928, 9370271, 9573168, 11964144, 4295288; Product type ps : structure; propanediol utilization protein PduJ/pduA 2045845..2046174 Escherichia fergusonii ATCC 35469 7122773 YP_002383118.1 CDS EFER_1990 NC_011740.1 2046192 2046476 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12007656, 8071226, 9352910, 10498708; Product type ps : structure; propanediol utilization protein pduA/pduJ 2046192..2046476 Escherichia fergusonii ATCC 35469 7124101 YP_002383119.1 CDS EFER_1991 NC_011740.1 2046491 2046769 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8071226, 9352910, 10498708; Product type ps : structure; propanediol utilization protein: polyhedral bodies pduJ or pduA 2046491..2046769 Escherichia fergusonii ATCC 35469 7122774 YP_002383120.1 CDS EFER_1993 NC_011740.1 2048436 2048693 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; ethanolamine utilization protein EutN/carboxysome structural protein Ccml 2048436..2048693 Escherichia fergusonii ATCC 35469 7123454 YP_002383121.1 CDS EFER_1995 NC_011740.1 2049854 2053276 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; Formate C-acetyltransferase 2049854..2053276 Escherichia fergusonii ATCC 35469 7123455 YP_002383122.1 CDS EFER_1996 NC_011740.1 2053328 2054275 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; pyruvate formate-lyase activating enzyme 2053328..2054275 Escherichia fergusonii ATCC 35469 7122776 YP_002383123.1 CDS EFER_1997 NC_011740.1 2054287 2054769 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; microcompartments protein 2054287..2054769 Escherichia fergusonii ATCC 35469 7122777 YP_002383124.1 CDS EFER_1998 NC_011740.1 2054766 2055386 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2054766..2055386 Escherichia fergusonii ATCC 35469 7122778 YP_002383125.1 CDS EFER_1999 NC_011740.1 2055398 2056063 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2055398..2056063 Escherichia fergusonii ATCC 35469 7122779 YP_002383126.1 CDS EFER_2000 NC_011740.1 2056096 2056497 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; membrane transport protein 2056096..2056497 Escherichia fergusonii ATCC 35469 7122780 YP_002383127.1 CDS EFER_2001 NC_011740.1 2056507 2056842 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; multidrug resistance protein 2056507..2056842 Escherichia fergusonii ATCC 35469 7122781 YP_002383128.1 CDS erfK NC_011740.1 2056909 2057835 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9298646; hypothetical protein complement(2056909..2057835) Escherichia fergusonii ATCC 35469 7122782 YP_002383129.1 CDS EFER_2003 NC_011740.1 2058050 2058535 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2058050..2058535) Escherichia fergusonii ATCC 35469 7122962 YP_002383130.1 CDS pocR NC_011740.1 2059035 2059952 R Evidence 2b : Function of strongly homologous gene; PubMedId : 8071226; Product type f : factor; propanediol utilization: transcriptional regulation complement(2059035..2059952) Escherichia fergusonii ATCC 35469 7122783 YP_002383131.1 CDS pduF NC_011740.1 2060147 2060941 R Evidence 2b : Function of strongly homologous gene; PubMedId : 9352910; Product type m : membrane component; propanediol diffusion facilitator complement(2060147..2060941) Escherichia fergusonii ATCC 35469 7120096 YP_002383132.1 CDS EFER_2008 NC_011740.1 2061443 2061727 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10498708; Product type ps : structure; propanediol utilization protein, polyhedral bodies (pduA-like) 2061443..2061727 Escherichia fergusonii ATCC 35469 7122570 YP_002383133.1 CDS EFER_2009 NC_011740.1 2061724 2062533 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; propanediol utilization protein: polyhedral bodies pduB 2061724..2062533 Escherichia fergusonii ATCC 35469 7122784 YP_002383134.1 CDS pduC NC_011740.1 2062552 2064216 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9352910; Product type e : enzyme; glycerol dehydratase large subunit 2062552..2064216 Escherichia fergusonii ATCC 35469 7122785 YP_002383135.1 CDS PduD NC_011740.1 2064227 2064889 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7706251, 12788698; Product type e : enzyme; propanediol utilization: diol dehydratase, medium subunit 2064227..2064889 Escherichia fergusonii ATCC 35469 7123501 YP_002383136.1 CDS pduE NC_011740.1 2064904 2065428 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9352910; Product type e : enzyme; propanediol utilization diol dehydratase small subunit 2064904..2065428 Escherichia fergusonii ATCC 35469 7122568 YP_002383137.1 CDS EFER_2013 NC_011740.1 2065439 2067271 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10498708, 12788698; Product type pe : enzyme; propanediol utilization: diol dehydratase reactivation PduG 2065439..2067271 Escherichia fergusonii ATCC 35469 7122569 YP_002383138.1 CDS EFER_2014 NC_011740.1 2067033 2067611 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12788698, 10498708; Product type pe : enzyme; propanediol utilization: diol dehydratase reactivation PduH 2067033..2067611 Escherichia fergusonii ATCC 35469 7122786 YP_002383139.1 CDS EFER_2016 NC_011740.1 2067932 2068366 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; propanediol utilization protein: polyhedral bodies PduK 2067932..2068366 Escherichia fergusonii ATCC 35469 7122787 YP_002383140.1 CDS EFER_2017 NC_011740.1 2068366 2068998 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10498708; hypothetical protein 2068366..2068998 Escherichia fergusonii ATCC 35469 7122788 YP_002383141.1 CDS EFER_2018 NC_011740.1 2068971 2069486 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2068971..2069486 Escherichia fergusonii ATCC 35469 7123535 YP_002383142.1 CDS EFER_2019 NC_011740.1 2069490 2069765 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10498708; Product type ps : structure; propanediol utilization: polyhedral bodies pduN 2069490..2069765 Escherichia fergusonii ATCC 35469 7122789 YP_002383143.1 CDS EFER_2020 NC_011740.1 2069776 2070783 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; propanediol utilization protein: B12 related pduO, Bifunctional ATP:cob(I)alamin adenosyltransferase/GlcG domain 2069776..2070783 Escherichia fergusonii ATCC 35469 7122790 YP_002383144.1 CDS EFER_2021 NC_011740.1 2070780 2072162 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10498708; Product type pe : enzyme; CoA-dependent proprionaldehyde dehydrogenase pduP 2070780..2072162 Escherichia fergusonii ATCC 35469 7124103 YP_002383145.1 CDS EFER_2022 NC_011740.1 2072173 2073285 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10498708; Product type pe : enzyme; propanediol utilization propanol dehydrogenase pduQ 2072173..2073285 Escherichia fergusonii ATCC 35469 7121195 YP_002383146.1 CDS EFER_2023 NC_011740.1 2073282 2074622 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; propanediol utilization protein: ferredoxin pduS 2073282..2074622 Escherichia fergusonii ATCC 35469 7121261 YP_002383147.1 CDS EFER_2024 NC_011740.1 2074625 2075179 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; propanediol utilization: polyhedral bodies pduT 2074625..2075179 Escherichia fergusonii ATCC 35469 7121262 YP_002383148.1 CDS EFER_2025 NC_011740.1 2075155 2075529 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10498708; Product type ps : structure; propanediol utilization protein: polyhedral bodies pduU 2075155..2075529 Escherichia fergusonii ATCC 35469 7123291 YP_002383149.1 CDS EFER_2026 NC_011740.1 2075531 2075980 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10498708; hypothetical protein 2075531..2075980 Escherichia fergusonii ATCC 35469 7123836 YP_002383150.1 CDS EFER_2027 NC_011740.1 2075970 2077184 D involved in coenzyme B(12)-dependent 1, 2-propanediol degradation; important for the synthesis of propionyl coenzyme A during growth on 1,2-propanediol; propionate kinase 2075970..2077184 Escherichia fergusonii ATCC 35469 7121263 YP_002383151.1 CDS yeeX NC_011740.1 2077294 2077629 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2077294..2077629) Escherichia fergusonii ATCC 35469 7121264 YP_002383152.1 CDS yeeA NC_011740.1 2077797 2078864 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 15919996; Inner membrane protein yeeA complement(2077797..2078864) Escherichia fergusonii ATCC 35469 7121549 YP_002383153.1 CDS sbmC NC_011740.1 2078962 2079429 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8709849, 9442027; Product type pe : enzyme; DNA gyrase inhibitor complement(2078962..2079429) Escherichia fergusonii ATCC 35469 7121545 YP_002383154.1 CDS EFER_2031 NC_011740.1 2080141 2080344 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2080141..2080344 Escherichia fergusonii ATCC 35469 7121752 YP_002383155.1 CDS EFER_2032 NC_011740.1 2080287 2082317 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; acyltransferase 2080287..2082317 Escherichia fergusonii ATCC 35469 7123837 YP_002383156.1 CDS EFER_2033 NC_011740.1 2082356 2084794 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; head-binding domain of phage tailspike protein complement(2082356..2084794) Escherichia fergusonii ATCC 35469 7121265 YP_002383157.1 CDS EFER_2034 NC_011740.1 2084927 2086771 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; DNA transfer protein from phage complement(2084927..2086771) Escherichia fergusonii ATCC 35469 7123292 YP_002383158.1 CDS EFER_2035 NC_011740.1 2086768 2088180 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; DNA transfer protein gp20 complement(2086768..2088180) Escherichia fergusonii ATCC 35469 7121266 YP_002383159.1 CDS EFER_2036 NC_011740.1 2088193 2088846 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; DNA transfer protein gp7 from phage origin complement(2088193..2088846) Escherichia fergusonii ATCC 35469 7121267 YP_002383160.1 CDS EFER_2037 NC_011740.1 2088821 2089303 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(2088821..2089303) Escherichia fergusonii ATCC 35469 7121268 YP_002383161.1 CDS GP NC_011740.1 2089300 2090148 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Packaged DNA stabilization protein gp26 complement(2089300..2090148) Escherichia fergusonii ATCC 35469 7121269 YP_002383162.1 CDS EFER_2039 NC_011740.1 2090148 2091566 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Packaged DNA stabilization protein from phage complement(2090148..2091566) Escherichia fergusonii ATCC 35469 7120603 YP_002383163.1 CDS GP NC_011740.1 2091567 2092178 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; DNA stabilization protein GP4 complement(2091567..2092178) Escherichia fergusonii ATCC 35469 7123293 YP_002383164.1 CDS EFER_2041 NC_011740.1 2092045 2092365 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(2092045..2092365) Escherichia fergusonii ATCC 35469 7123725 YP_002383165.1 CDS GP NC_011740.1 2092362 2093657 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Coat protein complement(2092362..2093657) Escherichia fergusonii ATCC 35469 7121270 YP_002383166.1 CDS GP NC_011740.1 2093657 2094568 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Scaffolding protein (protein gp8) complement(2093657..2094568) Escherichia fergusonii ATCC 35469 7120604 YP_002383167.1 CDS GP NC_011740.1 2094582 2096747 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Portal protein (protein gp1) complement(2094582..2096747) Escherichia fergusonii ATCC 35469 7120605 YP_002383168.1 CDS GP NC_011740.1 2096748 2098247 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; DNA packaging protein gp2 (Terminase large subunit) complement(2096748..2098247) Escherichia fergusonii ATCC 35469 7123726 YP_002383169.1 CDS GP NC_011740.1 2098225 2098719 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; DNA packaging protein gp3 (Terminase small subunit) complement(2098225..2098719) Escherichia fergusonii ATCC 35469 7120606 YP_002383170.1 CDS EFER_2047 NC_011740.1 2098737 2098916 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(2098737..2098916) Escherichia fergusonii ATCC 35469 7120607 YP_002383171.1 CDS EFER_2048 NC_011740.1 2098918 2099160 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(2098918..2099160) Escherichia fergusonii ATCC 35469 7123294 YP_002383172.1 CDS EFER_2049 NC_011740.1 2099513 2100274 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(2099513..2100274) Escherichia fergusonii ATCC 35469 7121271 YP_002383173.1 CDS EFER_2050 NC_011740.1 2100234 2100386 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; bacteriophage protein (Gene 65) complement(2100234..2100386) Escherichia fergusonii ATCC 35469 7121272 YP_002383174.1 CDS Rz NC_011740.1 2100374 2100853 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; lysis protein Rz complement(2100374..2100853) Escherichia fergusonii ATCC 35469 7123295 YP_002383175.1 CDS ybcS NC_011740.1 2100838 2101335 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3017988; Product type pe : enzyme; lysozyme; DLP12 prophage complement(2100838..2101335) Escherichia fergusonii ATCC 35469 7121187 YP_002383176.1 CDS EFER_2053 NC_011740.1 2101313 2101516 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(2101313..2101516) Escherichia fergusonii ATCC 35469 7123804 YP_002383177.1 CDS EFER_2054 NC_011740.1 2102187 2102810 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Antitermination protein Q complement(2102187..2102810) Escherichia fergusonii ATCC 35469 7123838 YP_002383178.1 CDS pph NC_011740.1 2102807 2103547 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Serine/threonine-protein phosphatase complement(2102807..2103547) Escherichia fergusonii ATCC 35469 7121273 YP_002383179.1 CDS EFER_2056 NC_011740.1 2103450 2103656 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(2103450..2103656) Escherichia fergusonii ATCC 35469 7120110 YP_002383180.1 CDS ninG NC_011740.1 2103653 2104264 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; protein ninG from prophage complement(2103653..2104264) Escherichia fergusonii ATCC 35469 7121274 YP_002383181.1 CDS EFER_2059 NC_011740.1 2104257 2104649 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(2104257..2104649) Escherichia fergusonii ATCC 35469 7120694 YP_002383182.1 CDS ninF NC_011740.1 2104639 2104818 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2104639..2104818) Escherichia fergusonii ATCC 35469 7123839 YP_002383183.1 CDS EFER_2061 NC_011740.1 2104818 2105237 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(2104818..2105237) Escherichia fergusonii ATCC 35469 7123204 YP_002383184.1 CDS EFER_2062 NC_011740.1 2105371 2105787 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; ninB protein complement(2105371..2105787) Escherichia fergusonii ATCC 35469 7121275 YP_002383185.1 CDS EFER_2063 NC_011740.1 2105784 2106080 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(2105784..2106080) Escherichia fergusonii ATCC 35469 7123840 YP_002383186.1 CDS EFER_2064 NC_011740.1 2106058 2106279 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(2106058..2106279) Escherichia fergusonii ATCC 35469 7121276 YP_002383187.1 CDS EFER_2066 NC_011740.1 2106581 2106727 D Evidence 6 : Doubtful CDS; Product type h : extrachromosomal origin; hypothetical protein 2106581..2106727 Escherichia fergusonii ATCC 35469 7121277 YP_002383188.1 CDS EFER_2067 NC_011740.1 2106745 2108121 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; replicative DNA helicase complement(2106745..2108121) Escherichia fergusonii ATCC 35469 7121278 YP_002383189.1 CDS EFER_2068 NC_011740.1 2108118 2109065 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2108118..2109065) Escherichia fergusonii ATCC 35469 7123841 YP_002383190.1 CDS EFER_2069 NC_011740.1 2109068 2109505 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2109068..2109505) Escherichia fergusonii ATCC 35469 7121279 YP_002383191.1 CDS EFER_2070 NC_011740.1 2109363 2109659 R Evidence 2b : Function of strongly homologous gene; PubMedId : 375198; Product type h : extrachromosomal origin; Regulatory protein CII from phage origin complement(2109363..2109659) Escherichia fergusonii ATCC 35469 7123033 YP_002383192.1 CDS cro NC_011740.1 2109766 2110026 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type h : extrachromosomal origin; regulatory protein from bacteriophage origin complement(2109766..2110026) Escherichia fergusonii ATCC 35469 7121281 YP_002383193.1 CDS cI NC_011740.1 2110072 2110779 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; repressor protein of bacteriophage origin 2110072..2110779 Escherichia fergusonii ATCC 35469 7123536 YP_002383194.1 CDS EFER_2073 NC_011740.1 2110886 2111263 D Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 2110886..2111263 Escherichia fergusonii ATCC 35469 7120892 YP_002383195.1 CDS EFER_2074 NC_011740.1 2111238 2111723 D Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 2111238..2111723 Escherichia fergusonii ATCC 35469 7121282 YP_002383196.1 CDS EFER_2075 NC_011740.1 2112100 2112525 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2112100..2112525 Escherichia fergusonii ATCC 35469 7123296 YP_002383197.1 CDS EFER_2076 NC_011740.1 2112547 2112864 R Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein complement(2112547..2112864) Escherichia fergusonii ATCC 35469 7121283 YP_002383198.1 CDS EFER_2077 NC_011740.1 2112796 2112996 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Restriction inhibitor protein ral 2112796..2112996 Escherichia fergusonii ATCC 35469 7121284 YP_002383199.1 CDS EFER_2078 NC_011740.1 2113118 2114137 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2113118..2114137 Escherichia fergusonii ATCC 35469 7121285 YP_002383200.1 CDS kil NC_011740.1 2114277 2114429 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; protein kil 2114277..2114429 Escherichia fergusonii ATCC 35469 7121286 YP_002383201.1 CDS EFER_2080 NC_011740.1 2114411 2114596 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2114411..2114596 Escherichia fergusonii ATCC 35469 7120815 YP_002383202.1 CDS EFER_2081 NC_011740.1 2114505 2114675 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2114505..2114675 Escherichia fergusonii ATCC 35469 7121287 YP_002383203.1 CDS erf NC_011740.1 2114656 2115291 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; DNA single-strand annealing protein 2114656..2115291 Escherichia fergusonii ATCC 35469 7123842 YP_002383204.1 CDS EFER_2083 NC_011740.1 2115201 2115674 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2115201..2115674 Escherichia fergusonii ATCC 35469 7122961 YP_002383205.1 CDS abc NC_011740.1 2115677 2115994 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Anti-RecBCD protein 2 2115677..2115994 Escherichia fergusonii ATCC 35469 7121288 YP_002383206.1 CDS EFER_2085 NC_011740.1 2115852 2116295 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2115852..2116295 Escherichia fergusonii ATCC 35469 7124007 YP_002383207.1 CDS EFER_2086 NC_011740.1 2116435 2116725 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2116435..2116725 Escherichia fergusonii ATCC 35469 7121289 YP_002383208.1 CDS EFER_2087 NC_011740.1 2116712 2117266 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2116712..2117266 Escherichia fergusonii ATCC 35469 7121290 YP_002383209.1 CDS EFER_2088 NC_011740.1 2117220 2117927 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2117220..2117927 Escherichia fergusonii ATCC 35469 7121291 YP_002383210.1 CDS EFER_2089 NC_011740.1 2117879 2118199 D Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein 2117879..2118199 Escherichia fergusonii ATCC 35469 7121292 YP_002383211.1 CDS EFER_2090 NC_011740.1 2118196 2118483 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2118196..2118483 Escherichia fergusonii ATCC 35469 7121293 YP_002383212.1 CDS EFER_2091 NC_011740.1 2118476 2118757 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2118476..2118757 Escherichia fergusonii ATCC 35469 7121294 YP_002383213.1 CDS EFER_2092 NC_011740.1 2118852 2119019 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2118852..2119019 Escherichia fergusonii ATCC 35469 7123843 YP_002383214.1 CDS int NC_011740.1 2119222 2120418 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; integrase complement(2119222..2120418) Escherichia fergusonii ATCC 35469 7121295 YP_002383215.1 CDS sbcB NC_011740.1 2120582 2122006 D Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 2120582..2122006 Escherichia fergusonii ATCC 35469 7120750 YP_002383216.1 CDS yeeD NC_011740.1 2122049 2122276 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2122049..2122276) Escherichia fergusonii ATCC 35469 7121193 YP_002383217.1 CDS yeeE NC_011740.1 2122290 2123348 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(2122290..2123348) Escherichia fergusonii ATCC 35469 7123338 YP_002383218.1 CDS yeeF NC_011740.1 2123526 2124884 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; amino-acid/amine transporter complement(2123526..2124884) Escherichia fergusonii ATCC 35469 7121546 YP_002383219.1 CDS yeeY NC_011740.1 2125150 2126079 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator complement(2125150..2126079) Escherichia fergusonii ATCC 35469 7123885 YP_002383220.1 CDS yeeZ NC_011740.1 2126125 2126949 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; epimerase complement(2126125..2126949) Escherichia fergusonii ATCC 35469 7121550 YP_002383221.1 CDS yoeB NC_011740.1 2127032 2127286 R Evidence 1b : Function experimentally demonstrated in the studied species; Product type f : factor; toxin of the YoeB-YefM toxin-antitoxin system complement(2127032..2127286) Escherichia fergusonii ATCC 35469 7121551 YP_002383222.1 CDS yefM NC_011740.1 2127283 2127534 R Antitoxin that counteracts the effect of the YoeB toxin; antitoxin YefM complement(2127283..2127534) Escherichia fergusonii ATCC 35469 7123914 YP_002383224.1 CDS hisG NC_011740.1 2128014 2128913 D long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 2128014..2128913 Escherichia fergusonii ATCC 35469 7123442 YP_002383225.1 CDS hisD NC_011740.1 2128919 2130223 D catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 2128919..2130223 Escherichia fergusonii ATCC 35469 7123998 YP_002383226.1 CDS hisC NC_011740.1 2130220 2131290 D catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 2130220..2131290 Escherichia fergusonii ATCC 35469 7122196 YP_002383227.1 CDS hisB NC_011740.1 2131290 2132357 D catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 2131290..2132357 Escherichia fergusonii ATCC 35469 7123997 YP_002383228.1 CDS hisH NC_011740.1 2132357 2132947 D with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2132357..2132947 Escherichia fergusonii ATCC 35469 7122195 YP_002383229.1 CDS hisA NC_011740.1 2132947 2133684 D catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2132947..2133684 Escherichia fergusonii ATCC 35469 7122198 YP_002383230.1 CDS hisF NC_011740.1 2133666 2134442 D catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2133666..2134442 Escherichia fergusonii ATCC 35469 7123441 YP_002383231.1 CDS hisI NC_011740.1 2134436 2135047 D catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase 2134436..2135047 Escherichia fergusonii ATCC 35469 7122197 YP_002383232.1 CDS EFER_2110 NC_011740.1 2135141 2136121 R Evidence 1b : Function experimentally demonstrated in the studied species; Product type m : membrane component; polysaccharide antigen chain regulator complement(2135141..2136121) Escherichia fergusonii ATCC 35469 7122199 YP_002383233.1 CDS ugd NC_011740.1 2136353 2137546 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9150218, 96326333; Product type e : enzyme; UDP-glucose 6-dehydrogenase complement(2136353..2137546) Escherichia fergusonii ATCC 35469 7121296 YP_002383234.1 CDS gnd NC_011740.1 2137769 2139175 R catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase complement(2137769..2139175) Escherichia fergusonii ATCC 35469 7122624 YP_002383235.1 CDS EFER_2113 NC_011740.1 2140610 2141467 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; glycosyltransferase complement(2140610..2141467) Escherichia fergusonii ATCC 35469 7123724 YP_002383236.1 CDS cpsG NC_011740.1 2141496 2142863 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93106949, 96326333, 7815923, 8759852; Product type e : enzyme; phosphomannomutase complement(2141496..2142863) Escherichia fergusonii ATCC 35469 7123844 YP_002383237.1 CDS EFER_2115 NC_011740.1 2142867 2144324 R Evidence 1b : Function experimentally demonstrated in the studied species; Product type e : enzyme; mannose-1-phosphate guanylyltransferase complement(2142867..2144324) Escherichia fergusonii ATCC 35469 7124105 YP_002383238.1 CDS nudD NC_011740.1 2144308 2144811 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96326333, 10913267, 7592609, 7815923, 8759852; Product type e : enzyme; GDP-mannose mannosyl hydrolase complement(2144308..2144811) Escherichia fergusonii ATCC 35469 7121297 YP_002383239.1 CDS fcl NC_011740.1 2144811 2145776 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96326333, 98132401, 9862812, 7815923, 8759852, 9473059; Product type e : enzyme; bifunctional GDP-fucose synthetase: GDP-4-dehydro-6-deoxy-D-mannose epimerase and GDP-4-dehydro-6-L-deoxygalactose reductase complement(2144811..2145776) Escherichia fergusonii ATCC 35469 7119669 YP_002383240.1 CDS gmd NC_011740.1 2145779 2146897 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20139699, 97400210, 10673432, 7815923, 8759852, 9257704, 14299611; Product type e : enzyme; GDP-D-mannose dehydratase complement(2145779..2146897) Escherichia fergusonii ATCC 35469 7119992 YP_002383241.1 CDS EFER_2119 NC_011740.1 2146919 2147743 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2146919..2147743) Escherichia fergusonii ATCC 35469 7123186 YP_002383242.1 CDS EFER_2120 NC_011740.1 2148530 2149204 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2148530..2149204) Escherichia fergusonii ATCC 35469 7121298 YP_002383243.1 CDS EFER_2121 NC_011740.1 2149194 2150384 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2149194..2150384) Escherichia fergusonii ATCC 35469 7123297 YP_002383244.1 CDS EFER_2122 NC_011740.1 2150311 2151474 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2150311..2151474) Escherichia fergusonii ATCC 35469 7121299 YP_002383245.1 CDS EFER_2123 NC_011740.1 2151474 2152154 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; chloramphenicol acetyltransferase (fragment) complement(2151474..2152154) Escherichia fergusonii ATCC 35469 7121300 YP_002383246.1 CDS EFER_2124 NC_011740.1 2152138 2153079 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2152138..2153079) Escherichia fergusonii ATCC 35469 7121301 YP_002383247.1 CDS EFER_2125 NC_011740.1 2153080 2154369 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein complement(2153080..2154369) Escherichia fergusonii ATCC 35469 7121302 YP_002383248.1 CDS galF NC_011740.1 2154751 2155644 R together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose; UTP--glucose-1-phosphate uridylyltransferase subunit GalF complement(2154751..2155644) Escherichia fergusonii ATCC 35469 7123298 YP_002383249.1 CDS wcaM NC_011740.1 2155812 2157206 R WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid; colanic acid biosynthesis protein complement(2155812..2157206) Escherichia fergusonii ATCC 35469 7120165 YP_002383250.1 CDS wcaL NC_011740.1 2157217 2158437 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96326333; Product type pe : enzyme; glycosyl transferase family protein complement(2157217..2158437) Escherichia fergusonii ATCC 35469 7122372 YP_002383251.1 CDS wcaK NC_011740.1 2158434 2159714 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96326333, 8759852, 11004393; Product type pe : enzyme; pyruvyl transferase complement(2158434..2159714) Escherichia fergusonii ATCC 35469 7124028 YP_002383252.1 CDS wzxC NC_011740.1 2159787 2161265 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96326333, 8759852; Product type pt : transporter; colanic acid exporter complement(2159787..2161265) Escherichia fergusonii ATCC 35469 7122371 YP_002383253.1 CDS wcaJ NC_011740.1 2161267 2162661 R WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid; UDP-glucose lipid carrier transferase complement(2161267..2162661) Escherichia fergusonii ATCC 35469 7122376 YP_002383254.1 CDS cpsG NC_011740.1 2162716 2164086 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93106949, 96326333, 7815923, 8759852; Product type e : enzyme; phosphomannomutase complement(2162716..2164086) Escherichia fergusonii ATCC 35469 7122370 YP_002383255.1 CDS cpsB NC_011740.1 2164367 2165803 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 82100097, 85006781, 92048476, 93122523, 96326333, 7815923, 8759852; Product type e : enzyme; mannose-1-phosphate guanyltransferase complement(2164367..2165803) Escherichia fergusonii ATCC 35469 7122797 YP_002383256.1 CDS wcaI NC_011740.1 2165806 2167029 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15670885, 96326333; Product type pe : enzyme; glycosyl transferase family protein complement(2165806..2167029) Escherichia fergusonii ATCC 35469 7122796 YP_002383257.1 CDS nudD NC_011740.1 2167026 2167505 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96326333, 10913267, 7592609, 7815923, 8759852; Product type e : enzyme; GDP-mannose mannosyl hydrolase complement(2167026..2167505) Escherichia fergusonii ATCC 35469 7122369 YP_002383258.1 CDS fcl NC_011740.1 2167508 2168473 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96326333, 98132401, 9862812, 7815923, 8759852, 9473059; Product type e : enzyme; bifunctional GDP-fucose synthetase: GDP-4-dehydro-6-deoxy-D-mannose epimerase and GDP-4-dehydro-6-L-deoxygalactose reductase complement(2167508..2168473) Escherichia fergusonii ATCC 35469 7119670 YP_002383259.1 CDS gmd NC_011740.1 2168476 2169597 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20139699, 97400210, 10673432, 7815923, 8759852, 9257704, 14299611; Product type e : enzyme; GDP-D-mannose dehydratase complement(2168476..2169597) Escherichia fergusonii ATCC 35469 7119993 YP_002383260.1 CDS wcaF NC_011740.1 2169624 2170172 R acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); colanic acid biosynthesis acetyltransferase WcaF complement(2169624..2170172) Escherichia fergusonii ATCC 35469 7120593 YP_002383261.1 CDS wcaE NC_011740.1 2170188 2170934 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11371548, 96326333, 8759852; Product type pe : enzyme; glycosyl transferase family protein complement(2170188..2170934) Escherichia fergusonii ATCC 35469 7122368 YP_002383262.1 CDS wcaD NC_011740.1 2171060 2172352 R essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance; colanic acid biosynthesis protein complement(2171060..2172352) Escherichia fergusonii ATCC 35469 7123470 YP_002383263.1 CDS wcaC NC_011740.1 2172255 2173472 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96326333; Product type pe : enzyme; glycosyl transferase family protein complement(2172255..2173472) Escherichia fergusonii ATCC 35469 7122367 YP_002383264.1 CDS wcaB NC_011740.1 2173469 2173957 R acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium; colanic acid biosynthesis acetyltransferase WcaB complement(2173469..2173957) Escherichia fergusonii ATCC 35469 7122366 YP_002383265.1 CDS wcaA NC_011740.1 2173960 2174799 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 96326333; Product type pe : enzyme; glycosyl transferase family protein complement(2173960..2174799) Escherichia fergusonii ATCC 35469 7122365 YP_002383266.1 CDS wzc NC_011740.1 2174928 2177090 R Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide); tyrosine kinase complement(2174928..2177090) Escherichia fergusonii ATCC 35469 7122364 YP_002383267.1 CDS wzb NC_011740.1 2177093 2177536 R Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis; tyrosine phosphatase complement(2177093..2177536) Escherichia fergusonii ATCC 35469 7123471 YP_002383268.1 CDS wza NC_011740.1 2177542 2178681 R Evidence 2b : Function of strongly homologous gene; PubMedId : 15090537, 96326333, 8759852, 8763957; Product type lp : lipoprotein; lipoprotein complement(2177542..2178681) Escherichia fergusonii ATCC 35469 7122375 YP_002383269.1 CDS yegH NC_011740.1 2179340 2180923 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; membrane protein 2179340..2180923 Escherichia fergusonii ATCC 35469 7122374 YP_002383270.1 CDS EFER_2148 NC_011740.1 2180880 2181005 R Evidence 6 : Doubtful CDS; hypothetical protein complement(2180880..2181005) Escherichia fergusonii ATCC 35469 7121554 YP_002383271.1 CDS EFER_2149 NC_011740.1 2181187 2182212 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transposase, IS110 family 2181187..2182212 Escherichia fergusonii ATCC 35469 7121303 YP_002383272.1 CDS asmA NC_011740.1 2182761 2184614 R YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs; assembly protein complement(2182761..2184614) Escherichia fergusonii ATCC 35469 7121304 YP_002383273.1 CDS dcd NC_011740.1 2184636 2185217 R Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase complement(2184636..2185217) Escherichia fergusonii ATCC 35469 7120566 YP_002383274.1 CDS udk NC_011740.1 2185309 2185950 R functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase complement(2185309..2185950) Escherichia fergusonii ATCC 35469 7122870 YP_002383275.1 CDS yegE NC_011740.1 2186287 2189604 D contains a MASE1 (Membrane-Associated Sensor) domain; potentially involved in signal transduction; sensor protein 2186287..2189604 Escherichia fergusonii ATCC 35469 7122622 YP_002383276.1 CDS alkA NC_011740.1 2189642 2190499 R inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine; 3-methyladenine DNA glycosylase complement(2189642..2190499) Escherichia fergusonii ATCC 35469 7121553 YP_002383277.1 CDS yegD NC_011740.1 2190633 2191985 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 6094528, 7940673, 7984428; Product type pf : factor; chaperone 2190633..2191985 Escherichia fergusonii ATCC 35469 7123457 YP_002383278.1 CDS yegI NC_011740.1 2191998 2193944 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2191998..2193944) Escherichia fergusonii ATCC 35469 7121552 YP_002383279.1 CDS yegJ NC_011740.1 2194145 2194606 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2194145..2194606 Escherichia fergusonii ATCC 35469 7121555 YP_002383280.1 CDS yegK NC_011740.1 2194671 2195432 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2194671..2195432) Escherichia fergusonii ATCC 35469 7123886 YP_002383281.1 CDS yegL NC_011740.1 2195429 2196088 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2195429..2196088) Escherichia fergusonii ATCC 35469 7123887 YP_002383282.1 CDS mdtA NC_011740.1 2197296 2198543 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtA 2197296..2198543 Escherichia fergusonii ATCC 35469 7121176 YP_002383283.1 CDS mdtB NC_011740.1 2198543 2201665 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtB 2198543..2201665 Escherichia fergusonii ATCC 35469 7121247 YP_002383284.1 CDS mdtC NC_011740.1 2201666 2204743 D Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate; multidrug efflux system subunit MdtC 2201666..2204743 Escherichia fergusonii ATCC 35469 7121248 YP_002383285.1 CDS mdtD NC_011740.1 2204744 2206159 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12107134, 21450803, 8282725; Product type t : transporter; multidrug efflux system protein MdtE 2204744..2206159 Escherichia fergusonii ATCC 35469 7121249 YP_002383286.1 CDS baeS NC_011740.1 2206156 2207559 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94110256, 8282725; Product type r : regulator; signal transduction histidine-protein kinase BaeS 2206156..2207559 Escherichia fergusonii ATCC 35469 7121250 YP_002383287.1 CDS baeR NC_011740.1 2207556 2208278 D response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport; DNA-binding transcriptional regulator BaeR 2207556..2208278 Escherichia fergusonii ATCC 35469 7121643 YP_002383288.1 CDS yegP NC_011740.1 2208458 2208790 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2208458..2208790 Escherichia fergusonii ATCC 35469 7121642 YP_002383289.1 CDS EFER_2169 NC_011740.1 2209034 2209285 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2209034..2209285 Escherichia fergusonii ATCC 35469 7123888 YP_002383290.1 CDS EFER_2170 NC_011740.1 2209287 2209583 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2209287..2209583 Escherichia fergusonii ATCC 35469 7121305 YP_002383291.1 CDS yegQ NC_011740.1 2209686 2211047 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; peptidase 2209686..2211047 Escherichia fergusonii ATCC 35469 7123299 YP_002383292.1 CDS yegS NC_011740.1 2211304 2212203 D cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role; lipid kinase 2211304..2212203 Escherichia fergusonii ATCC 35469 7123820 YP_002383293.1 CDS EFER_2173 NC_011740.1 2212277 2212975 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; phosphoglycolate phosphatase complement(2212277..2212975) Escherichia fergusonii ATCC 35469 7121558 YP_002383294.1 CDS EFER_2174 NC_011740.1 2212975 2214294 R Evidence 1b : Function experimentally demonstrated in the studied species; Product type t : transporter; Ribitol transporter complement(2212975..2214294) Escherichia fergusonii ATCC 35469 7121306 YP_002383295.1 CDS EFER_2175 NC_011740.1 2214321 2215784 R Evidence 1b : Function experimentally demonstrated in the studied species; Product type e : enzyme; Xylulose kinase complement(2214321..2215784) Escherichia fergusonii ATCC 35469 7121307 YP_002383296.1 CDS EFER_2176 NC_011740.1 2215798 2217210 R Evidence 1b : Function experimentally demonstrated in the studied species; Product type e : enzyme; D-arabinitol 4-dehydrogenase complement(2215798..2217210) Escherichia fergusonii ATCC 35469 7121308 YP_002383297.1 CDS EFER_2177 NC_011740.1 2217378 2218319 D Evidence 1b : Function experimentally demonstrated in the studied species; Product type r : regulator; D-arabitol repressor 2217378..2218319 Escherichia fergusonii ATCC 35469 7121309 YP_002383298.1 CDS EFER_2178 NC_011740.1 2218322 2219353 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; catabolite repressor protein complement(2218322..2219353) Escherichia fergusonii ATCC 35469 7121310 YP_002383299.1 CDS EFER_2179 NC_011740.1 2219512 2220264 D Evidence 1b : Function experimentally demonstrated in the studied species; Product type e : enzyme; Ribitol 2-dehydrogenase 2219512..2220264 Escherichia fergusonii ATCC 35469 7123845 YP_002383300.1 CDS EFER_2180 NC_011740.1 2220251 2221879 D Evidence 1b : Function experimentally demonstrated in the studied species; Product type e : enzyme; Ribitol kinase 2220251..2221879 Escherichia fergusonii ATCC 35469 7121311 YP_002383301.1 CDS EFER_2181 NC_011740.1 2221981 2223255 D Evidence 1b : Function experimentally demonstrated in the studied species; Product type t : transporter; Ribitol transporter 2221981..2223255 Escherichia fergusonii ATCC 35469 7121312 YP_002383302.1 CDS fbaB NC_011740.1 2223312 2224364 R catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase complement(2223312..2224364) Escherichia fergusonii ATCC 35469 7121313 YP_002383303.1 CDS EFER_2183 NC_011740.1 2224392 2224541 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2224392..2224541 Escherichia fergusonii ATCC 35469 7119991 YP_002383304.1 CDS EFER_2184 NC_011740.1 2224531 2225874 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2224531..2225874) Escherichia fergusonii ATCC 35469 7121314 YP_002383305.1 CDS EFER_2185 NC_011740.1 2225875 2228580 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2225875..2228580) Escherichia fergusonii ATCC 35469 7123300 YP_002383306.1 CDS EFER_2186 NC_011740.1 2228605 2231292 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2228605..2231292) Escherichia fergusonii ATCC 35469 7121315 YP_002383307.1 CDS EFER_2187 NC_011740.1 2231280 2233853 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2231280..2233853) Escherichia fergusonii ATCC 35469 7123301 YP_002383308.1 CDS yegX NC_011740.1 2233939 2234856 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; membrane-bound hydrolase complement(2233939..2234856) Escherichia fergusonii ATCC 35469 7121316 YP_002383309.1 CDS thiD NC_011740.1 2234822 2235622 R catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase complement(2234822..2235622) Escherichia fergusonii ATCC 35469 7121559 YP_002383310.1 CDS EFER_2190 NC_011740.1 2235619 2236407 R catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase complement(2235619..2236407) Escherichia fergusonii ATCC 35469 7121991 YP_002383311.1 CDS EFER_2191 NC_011740.1 2236426 2236587 D hypothetical protein 2236426..2236587 Escherichia fergusonii ATCC 35469 7121317 YP_002383312.1 CDS yohN NC_011740.1 2236821 2237165 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2236821..2237165 Escherichia fergusonii ATCC 35469 7123302 YP_002383313.1 CDS EFER_2193 NC_011740.1 2237217 2238257 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein complement(2237217..2238257) Escherichia fergusonii ATCC 35469 7123368 YP_002383314.1 CDS EFER_2194 NC_011740.1 2238261 2240744 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; Paral outer membrane protein, protein complement(2238261..2240744) Escherichia fergusonii ATCC 35469 7121318 YP_002383315.1 CDS EFER_2195 NC_011740.1 2240757 2241485 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; periplasmic chaperone protein , protein complement(2240757..2241485) Escherichia fergusonii ATCC 35469 7121319 YP_002383316.1 CDS EFER_2196 NC_011740.1 2241491 2242024 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; Paral fimbrial-like protein complement(2241491..2242024) Escherichia fergusonii ATCC 35469 7121815 YP_002383317.1 CDS EFER_2197 NC_011740.1 2242307 2242588 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2242307..2242588) Escherichia fergusonii ATCC 35469 7121877 YP_002383318.1 CDS mrp NC_011740.1 2242805 2243914 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91080852, 15601724, 2259334; Product type t : transporter; ATPase complement(2242805..2243914) Escherichia fergusonii ATCC 35469 7121878 YP_002383319.1 CDS metG NC_011740.1 2244082 2246115 D methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 2244082..2246115 Escherichia fergusonii ATCC 35469 7120969 YP_002383320.1 CDS EFER_2200 NC_011740.1 2246257 2250054 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2156810; Product type ph : phenotype; hypothetical protein 2246257..2250054 Escherichia fergusonii ATCC 35469 7120919 YP_002383321.1 CDS EFER_2201 NC_011740.1 2250067 2253861 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2156810; Product type pr : regulator; Molybdate metabolism regulator (molR) 2250067..2253861 Escherichia fergusonii ATCC 35469 7121879 YP_002383322.1 CDS yehI NC_011740.1 2253871 2257515 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2253871..2257515 Escherichia fergusonii ATCC 35469 7121880 YP_002383323.1 CDS yehK NC_011740.1 2257575 2257892 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2257575..2257892 Escherichia fergusonii ATCC 35469 7123341 YP_002383324.1 CDS yehL NC_011740.1 2259203 2260291 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16428726; Product type pf : factor; ABC transporter protein 2259203..2260291 Escherichia fergusonii ATCC 35469 7121560 YP_002383325.1 CDS yehM NC_011740.1 2260302 2262581 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2260302..2262581 Escherichia fergusonii ATCC 35469 7121561 YP_002383326.1 CDS yehP NC_011740.1 2262574 2263710 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2262574..2263710 Escherichia fergusonii ATCC 35469 7121562 YP_002383327.1 CDS yehQ NC_011740.1 2263602 2265701 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2263602..2265701 Escherichia fergusonii ATCC 35469 7121563 YP_002383328.1 CDS EFER_2209 NC_011740.1 2265837 2266307 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2265837..2266307 Escherichia fergusonii ATCC 35469 7121564 YP_002383329.1 CDS yehS NC_011740.1 2266350 2266820 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2266350..2266820) Escherichia fergusonii ATCC 35469 7121881 YP_002383330.1 CDS yehT NC_011740.1 2266867 2267586 R unknown function; when overproduced it confers drug-resistance; two-component response-regulatory protein YehT complement(2266867..2267586) Escherichia fergusonii ATCC 35469 7121565 YP_002383331.1 CDS yehU NC_011740.1 2267583 2269268 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15522865, 15322361; Product type rc : receptor; sensory kinase in two-component system with YehT complement(2267583..2269268) Escherichia fergusonii ATCC 35469 7119716 YP_002383332.1 CDS mlrA NC_011740.1 2269490 2270221 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11489123; Product type r : regulator; DNA-binding transcriptional regulator 2269490..2270221 Escherichia fergusonii ATCC 35469 7123048 YP_002383333.1 CDS yohO NC_011740.1 2270281 2270388 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2270281..2270388 Escherichia fergusonii ATCC 35469 7120937 YP_002383334.1 CDS yehW NC_011740.1 2270369 2271100 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter permease complement(2270369..2271100) Escherichia fergusonii ATCC 35469 7121736 YP_002383335.1 CDS yehX NC_011740.1 2271105 2272031 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter ATP-binding protein complement(2271105..2272031) Escherichia fergusonii ATCC 35469 7119777 YP_002383336.1 CDS yehY NC_011740.1 2272024 2273181 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter permease complement(2272024..2273181) Escherichia fergusonii ATCC 35469 7119778 YP_002383337.1 CDS yehZ NC_011740.1 2273188 2274105 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15251200; Product type pt : transporter; ABC transporter substrate-binding protein complement(2273188..2274105) Escherichia fergusonii ATCC 35469 7119779 YP_002383338.1 CDS bglX NC_011740.1 2274254 2276551 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96303506; Product type e : enzyme; beta-D-glucoside glucohydrolase, periplasmic complement(2274254..2276551) Escherichia fergusonii ATCC 35469 7119780 YP_002383339.1 CDS dld NC_011740.1 2276694 2278463 D component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; D-lactate dehydrogenase 2276694..2278463 Escherichia fergusonii ATCC 35469 7121664 YP_002383340.1 CDS pbpG NC_011740.1 2278502 2279434 R specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7; D-alanyl-D-alanine endopeptidase complement(2278502..2279434) Escherichia fergusonii ATCC 35469 7122907 YP_002383341.1 CDS yohC NC_011740.1 2279608 2280195 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(2279608..2280195) Escherichia fergusonii ATCC 35469 7122559 YP_002383342.1 CDS yohD NC_011740.1 2280365 2280943 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2280365..2280943 Escherichia fergusonii ATCC 35469 7121730 YP_002383343.1 CDS yohF NC_011740.1 2281073 2281834 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; acetoin dehydrogenase complement(2281073..2281834) Escherichia fergusonii ATCC 35469 7121731 YP_002383344.1 CDS dusC NC_011740.1 2282102 2283052 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 22095566; Product type e : enzyme; tRNA-dihydrouridine synthase C complement(2282102..2283052) Escherichia fergusonii ATCC 35469 7121732 YP_002383345.1 CDS yohJ NC_011740.1 2283329 2283727 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2283329..2283727 Escherichia fergusonii ATCC 35469 7122929 YP_002383346.1 CDS yohK NC_011740.1 2283724 2284419 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2283724..2284419 Escherichia fergusonii ATCC 35469 7121733 YP_002383347.1 CDS cdd NC_011740.1 2284549 2285433 D Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 2284549..2285433 Escherichia fergusonii ATCC 35469 7121734 YP_002383348.1 CDS sanA NC_011740.1 2285580 2286299 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 96125233, 1567863, 8550448; hypothetical protein 2285580..2286299 Escherichia fergusonii ATCC 35469 7120874 YP_002383349.1 CDS yeiS NC_011740.1 2286302 2286541 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2286302..2286541 Escherichia fergusonii ATCC 35469 7121189 YP_002383350.1 CDS yeiT NC_011740.1 2286860 2288098 D function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; oxidoreductase 2286860..2288098 Escherichia fergusonii ATCC 35469 7119791 YP_002383351.1 CDS yeiA NC_011740.1 2288092 2289327 D catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase 2288092..2289327 Escherichia fergusonii ATCC 35469 7119792 YP_002383352.1 CDS mglC NC_011740.1 2289398 2290408 R ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex; beta-methylgalactoside transporter inner membrane protein complement(2289398..2290408) Escherichia fergusonii ATCC 35469 7123592 YP_002383353.1 CDS mglA NC_011740.1 2290424 2291944 R with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains; galactose/methyl galaxtoside transporter ATP-binding protein complement(2290424..2291944) Escherichia fergusonii ATCC 35469 7123242 YP_002383354.1 CDS mglB NC_011740.1 2292005 2293003 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87286407, 92049246, 1719366, 3057628, 3302609, 3600760, 6340108, 6885805, 7012152, 9298646; Product type t : transporter; methyl-galactoside ABC transporter periplasmic-binding protein complement(2292005..2293003) Escherichia fergusonii ATCC 35469 7123777 YP_002383355.1 CDS galS NC_011740.1 2293302 2294360 R negative regulator of the mglBAC operon for galactose utilization; DNA-binding transcriptional regulator GalS complement(2293302..2294360) Escherichia fergusonii ATCC 35469 7120928 YP_002383356.1 CDS yeiB NC_011740.1 2294468 2295625 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(2294468..2295625) Escherichia fergusonii ATCC 35469 7120170 YP_002383357.1 CDS folE NC_011740.1 2295642 2296310 R involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I complement(2295642..2296310) Escherichia fergusonii ATCC 35469 7119781 YP_002383358.1 CDS frmC NC_011740.1 2296567 2297403 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16567800; Product type e : enzyme; S-formylglutathione hydrolase 2296567..2297403 Escherichia fergusonii ATCC 35469 7123003 YP_002383359.1 CDS cirA NC_011740.1 2297434 2299413 R Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein; colicin I receptor complement(2297434..2299413) Escherichia fergusonii ATCC 35469 7124143 YP_002383360.1 CDS lysP NC_011740.1 2299696 2301165 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92250419, 94252996, 1315732, 7551055; Product type t : transporter; lysine transporter complement(2299696..2301165) Escherichia fergusonii ATCC 35469 7123237 YP_002383361.1 CDS yeiE NC_011740.1 2301334 2302203 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12400704, 1315732; Product type pr : regulator; DNA-binding transcriptional regulator complement(2301334..2302203) Escherichia fergusonii ATCC 35469 7121216 YP_002383362.1 CDS yeiH NC_011740.1 2302303 2303352 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2302303..2303352 Escherichia fergusonii ATCC 35469 7119783 YP_002383363.1 CDS nfo NC_011740.1 2303426 2304283 D Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 2303426..2304283 Escherichia fergusonii ATCC 35469 7119784 YP_002383364.1 CDS yeiI NC_011740.1 2304287 2305375 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 2304287..2305375 Escherichia fergusonii ATCC 35469 7123202 YP_002383365.1 CDS yeiJ NC_011740.1 2305430 2306680 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; sodium/proton nucleoside transporter complement(2305430..2306680) Escherichia fergusonii ATCC 35469 7119785 YP_002383366.1 CDS EFER_2247 NC_011740.1 2306694 2306810 R Evidence 6 : Doubtful CDS; hypothetical protein complement(2306694..2306810) Escherichia fergusonii ATCC 35469 7119786 YP_002383367.1 CDS rihB NC_011740.1 2306780 2307721 R Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively; ribonucleoside hydrolase 2 complement(2306780..2307721) Escherichia fergusonii ATCC 35469 7121882 YP_002383368.1 CDS yeiL NC_011740.1 2307890 2308549 D activator of nucleoside metabolism; DNA-binding transcriptional activator YeiL 2307890..2308549 Escherichia fergusonii ATCC 35469 7121410 YP_002383369.1 CDS yeiM NC_011740.1 2308618 2309868 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; sodium/proton nucleoside transporter complement(2308618..2309868) Escherichia fergusonii ATCC 35469 7123593 YP_002383370.1 CDS yeiN NC_011740.1 2309962 2310900 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2309962..2310900) Escherichia fergusonii ATCC 35469 7119787 YP_002383371.1 CDS yeiC NC_011740.1 2310888 2311934 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein complement(2310888..2311934) Escherichia fergusonii ATCC 35469 7119788 YP_002383372.1 CDS fruA NC_011740.1 2312253 2313980 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system fructose-specific transporter subunit IIBC complement(2312253..2313980) Escherichia fergusonii ATCC 35469 7119782 YP_002383373.1 CDS fruK NC_011740.1 2313955 2314893 R converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers; 1-phosphofructokinase complement(2313955..2314893) Escherichia fergusonii ATCC 35469 7123015 YP_002383374.1 CDS fruB NC_011740.1 2314893 2316023 R phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr; PTS system fructose-specific transporter subunit IIA/HPr protein complement(2314893..2316023) Escherichia fergusonii ATCC 35469 7123571 YP_002383375.1 CDS setB NC_011740.1 2316288 2317547 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10438463, 10209755; Product type t : transporter; lactose/glucose efflux system 2316288..2317547 Escherichia fergusonii ATCC 35469 7123016 YP_002383376.1 CDS yeiW NC_011740.1 2317544 2317798 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2317544..2317798) Escherichia fergusonii ATCC 35469 7121773 YP_002383377.1 CDS yeiP NC_011740.1 2317955 2318527 D Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein; elongation factor P 2317955..2318527 Escherichia fergusonii ATCC 35469 7119794 YP_002383378.1 CDS insG NC_011740.1 2318576 2319904 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; IS4 transposase; KpLE2 phage-like element complement(2318576..2319904) Escherichia fergusonii ATCC 35469 7119789 YP_002383379.1 CDS yeiQ NC_011740.1 2320154 2321629 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; sugar dehydrogenase 2320154..2321629 Escherichia fergusonii ATCC 35469 7123214 YP_002383380.1 CDS yeiR NC_011740.1 2321741 2322733 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 2321741..2322733 Escherichia fergusonii ATCC 35469 7119790 YP_002383381.1 CDS yeiU NC_011740.1 2322770 2323483 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; undecaprenyl pyrophosphate phosphatase 2322770..2323483 Escherichia fergusonii ATCC 35469 7123594 YP_002383382.1 CDS spr NC_011740.1 2323897 2324463 D by similarity, Spr seems to have peptidase activity; involved in thermoresistance; outer membrane lipoprotein 2323897..2324463 Escherichia fergusonii ATCC 35469 7119793 YP_002383383.1 CDS EFER_2266 NC_011740.1 2324646 2326202 D Evidence 1b : Function experimentally demonstrated in the studied species; Product type pm : membrane component; hypothetical protein 2324646..2326202 Escherichia fergusonii ATCC 35469 7121810 YP_002383384.1 CDS yejA NC_011740.1 2326239 2328095 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; oligopeptide ABC transporter substrate-binding protein 2326239..2328095 Escherichia fergusonii ATCC 35469 7121883 YP_002383385.1 CDS yejB NC_011740.1 2328096 2329190 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; oligopeptide ABC transporter permease 2328096..2329190 Escherichia fergusonii ATCC 35469 7119795 YP_002383386.1 CDS yejE NC_011740.1 2329190 2330215 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; oligopeptide ABC transporter permease 2329190..2330215 Escherichia fergusonii ATCC 35469 7119796 YP_002383387.1 CDS yejF NC_011740.1 2330169 2331806 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; oligopeptide ABC transporter ATP-binding protein 2330169..2331806 Escherichia fergusonii ATCC 35469 7119797 YP_002383388.1 CDS yejG NC_011740.1 2331810 2332172 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2331810..2332172) Escherichia fergusonii ATCC 35469 7123049 YP_002383389.1 CDS bcr NC_011740.1 2332483 2333673 R Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance; bicyclomycin/multidrug efflux system protein complement(2332483..2333673) Escherichia fergusonii ATCC 35469 7123050 YP_002383390.1 CDS rsuA NC_011740.1 2333701 2334396 R catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA; 16S rRNA pseudouridylate synthase A complement(2333701..2334396) Escherichia fergusonii ATCC 35469 7121648 YP_002383391.1 CDS yejH NC_011740.1 2334545 2336305 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; nucleic acid ATP-dependent helicase 2334545..2336305 Escherichia fergusonii ATCC 35469 7121154 YP_002383392.1 CDS rplY NC_011740.1 2336430 2336714 D the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 2336430..2336714 Escherichia fergusonii ATCC 35469 7119798 YP_002383393.1 CDS EFER_2276 NC_011740.1 2336912 2337796 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hydrolase complement(2336912..2337796) Escherichia fergusonii ATCC 35469 7121111 YP_002383394.1 CDS yejK NC_011740.1 2338117 2339121 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99296598, 10368163; Product type f : factor; nucleoid-associated protein NdpA complement(2338117..2339121) Escherichia fergusonii ATCC 35469 7123941 YP_002383395.1 CDS yejL NC_011740.1 2339303 2339530 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2339303..2339530 Escherichia fergusonii ATCC 35469 7119799 YP_002383396.1 CDS yejM NC_011740.1 2339561 2341321 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hydrolase 2339561..2341321 Escherichia fergusonii ATCC 35469 7119800 YP_002383397.1 CDS EFER_2281 NC_011740.1 2341945 2342322 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2341945..2342322 Escherichia fergusonii ATCC 35469 7120036 YP_002383398.1 CDS ymgD NC_011740.1 2342326 2342658 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2342326..2342658 Escherichia fergusonii ATCC 35469 7121884 YP_002383399.1 CDS narP NC_011740.1 2342911 2343561 D nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes; transcriptional regulator NarP 2342911..2343561 Escherichia fergusonii ATCC 35469 7121689 YP_002383400.1 CDS ccmH NC_011740.1 2343601 2344653 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 11756453, 12196152, 87260957, 91194558, 95362656, 9914305, 7635817; Product type pe : enzyme; heme lyase, CcmH subunit complement(2343601..2344653) Escherichia fergusonii ATCC 35469 7123201 YP_002383401.1 CDS ccmG NC_011740.1 2344650 2345207 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 12196152, 9716493, 9770295, 11256948, 11350062, 11843181, 7635817, 9537397; Product type e : enzyme; periplasmic thioredoxin of cytochrome c-type biogenesis complement(2344650..2345207) Escherichia fergusonii ATCC 35469 7123768 YP_002383402.1 CDS ccmF NC_011740.1 2345204 2347147 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 11756453, 12196152, 87260957, 8842153, 91194558, 95362656, 9716493, 7635817; Product type e : enzyme; heme lyase, CcmF subunit complement(2345204..2347147) Escherichia fergusonii ATCC 35469 7120872 YP_002383403.1 CDS ccmE NC_011740.1 2347144 2347623 R CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE complement(2347144..2347623) Escherichia fergusonii ATCC 35469 7120871 YP_002383404.1 CDS ccmD NC_011740.1 2347620 2347829 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 12196152, 95362656, 9716493, 7635817; Product type f : factor; cytochrome c biogenesis protein complement(2347620..2347829) Escherichia fergusonii ATCC 35469 7120870 YP_002383405.1 CDS ccmC NC_011740.1 2347826 2348563 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 12196152, 14532274, 21413853, 95362656, 7635817; Product type t : transporter; heme ABC transporter membrane protein complement(2347826..2348563) Escherichia fergusonii ATCC 35469 7120869 YP_002383406.1 CDS ccmB NC_011740.1 2348605 2349267 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10339610, 12196152, 95362656, 9716493, 7635817; Product type t : transporter; heme ABC transporter membrane protein complement(2348605..2349267) Escherichia fergusonii ATCC 35469 7123767 YP_002383407.1 CDS ccmA NC_011740.1 2349264 2349887 R ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA complement(2349264..2349887) Escherichia fergusonii ATCC 35469 7120868 YP_002383408.1 CDS napC NC_011740.1 2349902 2350504 R with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone; cytochrome c-type protein NapC complement(2349902..2350504) Escherichia fergusonii ATCC 35469 7120867 YP_002383409.1 CDS napB NC_011740.1 2350514 2350963 R small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA; citrate reductase cytochrome c-type subunit complement(2350514..2350963) Escherichia fergusonii ATCC 35469 7123734 YP_002383410.1 CDS napH NC_011740.1 2350960 2351823 R part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; quinol dehydrogenase membrane component complement(2350960..2351823) Escherichia fergusonii ATCC 35469 7120671 YP_002383411.1 CDS napG NC_011740.1 2351810 2352505 R part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway; quinol dehydrogenase periplasmic component complement(2351810..2352505) Escherichia fergusonii ATCC 35469 7120674 YP_002383412.1 CDS napA NC_011740.1 2352512 2354998 R periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC; nitrate reductase catalytic subunit complement(2352512..2354998) Escherichia fergusonii ATCC 35469 7120673 YP_002383413.1 CDS napD NC_011740.1 2354995 2355258 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96228696, 99395037; Product type f : factor; assembly protein for periplasmic nitrate reductase complement(2354995..2355258) Escherichia fergusonii ATCC 35469 7120670 YP_002383414.1 CDS napF NC_011740.1 2355248 2355742 R Predicted role in electron transfer to the periplasmic nitrate reductase protein NapA.; ferredoxin-type protein complement(2355248..2355742) Escherichia fergusonii ATCC 35469 7123735 YP_002383415.1 CDS eco NC_011740.1 2356147 2356635 D serine protease inhibitor, inhibits trypsin and other proteases; ecotin 2356147..2356635 Escherichia fergusonii ATCC 35469 7120672 YP_002383416.1 CDS ybiO NC_011740.1 2356816 2359041 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 2356816..2359041 Escherichia fergusonii ATCC 35469 7122935 YP_002383417.1 CDS ybiN NC_011740.1 2359038 2359964 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; SAM-dependent methyltransferase complement(2359038..2359964) Escherichia fergusonii ATCC 35469 7122100 YP_002383418.1 CDS ybiM NC_011740.1 2360095 2360499 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2360095..2360499 Escherichia fergusonii ATCC 35469 7123425 YP_002383419.1 CDS fiu NC_011740.1 2360764 2363046 D Fiu; YbiL; porin involved in the uptake of iron complexed with catecholate siderophores (e.g. dihydroxybenzoylserine, dihydroxybenzoate) and beta lactam agents; Fiu interacts with TonB which provides the energy required for transport across the outer membrane; acts as a receptor for iron-siderophores and microcins E492, M, and H47; outer membrane protein; catecholate siderophore receptor Fiu 2360764..2363046 Escherichia fergusonii ATCC 35469 7122099 YP_002383420.1 CDS ybiX NC_011740.1 2363088 2363765 D Evidence 4 : Homologs of previously reported genes of unknown function; hydroxylase 2363088..2363765 Escherichia fergusonii ATCC 35469 7123629 YP_002383421.1 CDS ybiI NC_011740.1 2363839 2364105 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2363839..2364105 Escherichia fergusonii ATCC 35469 7122104 YP_002383422.1 CDS ybiJ NC_011740.1 2364370 2364630 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2364370..2364630 Escherichia fergusonii ATCC 35469 7122097 YP_002383423.1 CDS ybiC NC_011740.1 2364772 2365857 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8405966; Product type pe : enzyme; hypothetical protein complement(2364772..2365857) Escherichia fergusonii ATCC 35469 7122098 YP_002383424.1 CDS ybiB NC_011740.1 2365998 2366960 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; glycosyl transferase family protein complement(2365998..2366960) Escherichia fergusonii ATCC 35469 7122095 YP_002383425.1 CDS dinG NC_011740.1 2366988 2369138 R helicase involved in DNA repair and perhaps also replication; ATP-dependent DNA helicase DinG complement(2366988..2369138) Escherichia fergusonii ATCC 35469 7122094 YP_002383426.1 CDS ybiA NC_011740.1 2369258 2369740 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2369258..2369740 Escherichia fergusonii ATCC 35469 7122899 YP_002383427.1 CDS rhlE NC_011740.1 2369972 2371336 R this helicase is not essential cell growth; ATP-dependent RNA helicase RhlE complement(2369972..2371336) Escherichia fergusonii ATCC 35469 7123424 YP_002383428.1 CDS ybiH NC_011740.1 2371565 2372236 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator 2371565..2372236 Escherichia fergusonii ATCC 35469 7123315 YP_002383429.1 CDS ybhG NC_011740.1 2372236 2373234 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16092522; Product type pt : transporter; hypothetical protein 2372236..2373234 Escherichia fergusonii ATCC 35469 7122096 YP_002383430.1 CDS ybhF NC_011740.1 2373227 2374963 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter ATP-binding protein 2373227..2374963 Escherichia fergusonii ATCC 35469 7123976 YP_002383431.1 CDS ybhS NC_011740.1 2374956 2376089 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter permease 2374956..2376089 Escherichia fergusonii ATCC 35469 7123975 YP_002383432.1 CDS ybhR NC_011740.1 2376100 2377206 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter permease 2376100..2377206 Escherichia fergusonii ATCC 35469 7122093 YP_002383433.1 CDS ybhQ NC_011740.1 2377168 2377578 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(2377168..2377578) Escherichia fergusonii ATCC 35469 7122092 YP_002383434.1 CDS ybhP NC_011740.1 2377711 2378472 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; metal-dependent hydrolase 2377711..2378472 Escherichia fergusonii ATCC 35469 7122091 YP_002383435.1 CDS ybhO NC_011740.1 2378469 2379710 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20102623, 10634942; Product type e : enzyme; cardiolipin synthase 2 2378469..2379710 Escherichia fergusonii ATCC 35469 7122090 YP_002383436.1 CDS ybhN NC_011740.1 2379710 2380666 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2379710..2380666 Escherichia fergusonii ATCC 35469 7122089 YP_002383437.1 CDS EFER_2321 NC_011740.1 2380670 2380933 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2380670..2380933) Escherichia fergusonii ATCC 35469 7123978 YP_002383438.1 CDS EFER_2322 NC_011740.1 2380905 2381273 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2380905..2381273) Escherichia fergusonii ATCC 35469 7121885 YP_002383439.1 CDS ybhM NC_011740.1 2381320 2382141 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(2381320..2382141) Escherichia fergusonii ATCC 35469 7123942 YP_002383440.1 CDS EFER_2324 NC_011740.1 2382232 2383893 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transmembrane protein (N-terminal); phosphatase (C-terminal) complement(2382232..2383893) Escherichia fergusonii ATCC 35469 7123977 YP_002383441.1 CDS ybhL NC_011740.1 2384256 2384960 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(2384256..2384960) Escherichia fergusonii ATCC 35469 7121886 YP_002383442.1 CDS moaE NC_011740.1 2385007 2385459 R catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin guanine dinucleotide biosynthesis protein MoaE complement(2385007..2385459) Escherichia fergusonii ATCC 35469 7122088 YP_002383443.1 CDS moaD NC_011740.1 2385461 2385706 R catalyzes the conversion of molybdopterin precursor Z into molybdopterin; molybdopterin synthase small subunit complement(2385461..2385706) Escherichia fergusonii ATCC 35469 7120947 YP_002383444.1 CDS moaC NC_011740.1 2385699 2386184 R MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC complement(2385699..2386184) Escherichia fergusonii ATCC 35469 7123246 YP_002383445.1 CDS moaB NC_011740.1 2386187 2386699 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93368423; Product type pf : factor; molybdopterin biosynthesis protein B complement(2386187..2386699) Escherichia fergusonii ATCC 35469 7123245 YP_002383446.1 CDS moaA NC_011740.1 2386721 2387710 R together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A complement(2386721..2387710) Escherichia fergusonii ATCC 35469 7120946 YP_002383447.1 CDS ybhK NC_011740.1 2388107 2389015 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16272399; Product type pe : enzyme; transferase 2388107..2389015 Escherichia fergusonii ATCC 35469 7123780 YP_002383448.1 CDS uvrB NC_011740.1 2389053 2391074 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B complement(2389053..2391074) Escherichia fergusonii ATCC 35469 7122087 YP_002383449.1 CDS bioD NC_011740.1 2391647 2392336 R DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase complement(2391647..2392336) Escherichia fergusonii ATCC 35469 7122646 YP_002383450.1 CDS bioC NC_011740.1 2392323 2393078 R methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth; biotin biosynthesis protein BioC complement(2392323..2393078) Escherichia fergusonii ATCC 35469 7121668 YP_002383451.1 CDS EFER_2336 NC_011740.1 2393053 2393130 D hypothetical protein 2393053..2393130 Escherichia fergusonii ATCC 35469 7121667 YP_002383452.1 CDS bioF NC_011740.1 2393065 2394219 R catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase complement(2393065..2394219) Escherichia fergusonii ATCC 35469 7121887 YP_002383453.1 CDS bioB NC_011740.1 2394216 2395256 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11834738, 12475249, 14704425, 14967041, 20250955, 89066784, 94170810, 94190882, 97382445, 11686925; Product type e : enzyme; biotin synthase complement(2394216..2395256) Escherichia fergusonii ATCC 35469 7121669 YP_002383454.1 CDS bioA NC_011740.1 2395343 2396632 D catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 2395343..2396632 Escherichia fergusonii ATCC 35469 7121666 YP_002383455.1 CDS ybhB NC_011740.1 2396691 2397167 D YbhB; similar to rat and human kinase inhibitory proteins; kinase inhibitor protein 2396691..2397167 Escherichia fergusonii ATCC 35469 7121665 YP_002383456.1 CDS ybhC NC_011740.1 2397319 2398602 D outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase family; pectinesterase 2397319..2398602 Escherichia fergusonii ATCC 35469 7123974 YP_002383457.1 CDS pgl NC_011740.1 2398747 2399742 R catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; 6-phosphogluconolactonase complement(2398747..2399742) Escherichia fergusonii ATCC 35469 7122086 YP_002383458.1 CDS ybhA NC_011740.1 2399909 2400727 D YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily; phosphotransferase 2399909..2400727 Escherichia fergusonii ATCC 35469 7122589 YP_002383459.1 CDS modC NC_011740.1 2400728 2401786 R Part of the ABC transporter complex modABC involved in molybdenum import; molybdate transporter ATP-binding protein complement(2400728..2401786) Escherichia fergusonii ATCC 35469 7122085 YP_002383460.1 CDS modB NC_011740.1 2401789 2402478 R part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease complement(2401789..2402478) Escherichia fergusonii ATCC 35469 7120951 YP_002383461.1 CDS modA NC_011740.1 2402478 2403254 R with ModCB is involved in the high-affinity transport of molybdate; molybdate transporter periplasmic protein complement(2402478..2403254) Escherichia fergusonii ATCC 35469 7120950 YP_002383462.1 CDS EFER_2347 NC_011740.1 2403399 2403650 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; outer membrane or exported complement(2403399..2403650) Escherichia fergusonii ATCC 35469 7120949 YP_002383463.1 CDS modE NC_011740.1 2403677 2404465 D represses the modABCD operon and activates the moaABCD and napFDAGHBC operons; DNA-binding transcriptional regulator ModE 2403677..2404465 Escherichia fergusonii ATCC 35469 7121888 YP_002383464.1 CDS modF NC_011740.1 2404533 2406005 D contains 2 ATP-binding cassettes; involved in the transport of molybdenum; molybdenum transport ATP-binding protein ModF 2404533..2406005 Escherichia fergusonii ATCC 35469 7120952 YP_002383465.1 CDS galE NC_011740.1 2406266 2407282 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89274199, 92253563, 92338916, 3022232, 6301942, 8564363, 8611559, 8931134, 9174344, 9271499, 9708982; Product type e : enzyme; UDP-galactose-4-epimerase 2406266..2407282 Escherichia fergusonii ATCC 35469 7120953 YP_002383466.1 CDS galT NC_011740.1 2407292 2408338 D catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase 2407292..2408338 Escherichia fergusonii ATCC 35469 7120164 YP_002383467.1 CDS galK NC_011740.1 2408342 2409490 D catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 2408342..2409490 Escherichia fergusonii ATCC 35469 7120171 YP_002383468.1 CDS galM NC_011740.1 2409484 2410524 D catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose; aldose 1-epimerase 2409484..2410524 Escherichia fergusonii ATCC 35469 7120166 YP_002383469.1 CDS gpmA NC_011740.1 2410727 2411479 D 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 2410727..2411479 Escherichia fergusonii ATCC 35469 7120167 YP_002383470.1 CDS EFER_2355 NC_011740.1 2411457 2411552 R hypothetical protein complement(2411457..2411552) Escherichia fergusonii ATCC 35469 7123187 YP_002383471.1 CDS aroG NC_011740.1 2411620 2412672 R catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase complement(2411620..2412672) Escherichia fergusonii ATCC 35469 7121889 YP_002383472.1 CDS ybgS NC_011740.1 2412988 2413368 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2412988..2413368 Escherichia fergusonii ATCC 35469 7120549 YP_002383473.1 CDS zitB NC_011740.1 2413482 2414417 D involved in zinc efflux across the cytoplasmic membrane; zinc transporter ZitB 2413482..2414417 Escherichia fergusonii ATCC 35469 7122084 YP_002383474.1 CDS pnuC NC_011740.1 2414414 2415133 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 219824, 90330519; Product type t : transporter; nicotinamide mononucleotide transporter complement(2414414..2415133) Escherichia fergusonii ATCC 35469 7123047 YP_002383475.1 CDS nadA NC_011740.1 2415171 2416214 R 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase complement(2415171..2416214) Escherichia fergusonii ATCC 35469 7120095 YP_002383476.1 CDS ybgF NC_011740.1 2417459 2418250 R periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity; tol-pal system protein YbgF complement(2417459..2418250) Escherichia fergusonii ATCC 35469 7120071 YP_002383477.1 CDS pal NC_011740.1 2418260 2418781 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11790745, 87133578, 92244043, 99403391, 11173492, 2687247; Product type lp : lipoprotein; peptidoglycan-associated outer membrane lipoprotein complement(2418260..2418781) Escherichia fergusonii ATCC 35469 7122077 YP_002383478.1 CDS tolB NC_011740.1 2418816 2420108 R forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB complement(2418816..2420108) Escherichia fergusonii ATCC 35469 7122551 YP_002383479.1 CDS EFER_2365 NC_011740.1 2420241 2421452 R Evidence 1b : Function experimentally demonstrated in the studied species; Product type m : membrane component; TolA protein complement(2420241..2421452) Escherichia fergusonii ATCC 35469 7122140 YP_002383480.1 CDS tolR NC_011740.1 2421515 2421943 R membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolR complement(2421515..2421943) Escherichia fergusonii ATCC 35469 7121890 YP_002383481.1 CDS tolQ NC_011740.1 2421947 2422639 R membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins; colicin uptake protein TolQ complement(2421947..2422639) Escherichia fergusonii ATCC 35469 7122142 YP_002383482.1 CDS ybgC NC_011740.1 2422636 2423040 R catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components; acyl-CoA thioester hydrolase YbgC complement(2422636..2423040) Escherichia fergusonii ATCC 35469 7123430 YP_002383483.1 CDS ybgE NC_011740.1 2423190 2423483 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(2423190..2423483) Escherichia fergusonii ATCC 35469 7122075 YP_002383484.1 CDS cydB NC_011740.1 2423611 2424750 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87299685, 89255232, 91035243, 2843510, 3138232; Product type c : carrier; cytochrome d terminal oxidase subunit II complement(2423611..2424750) Escherichia fergusonii ATCC 35469 7122076 YP_002383485.1 CDS cydA NC_011740.1 2424766 2426334 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87299685, 89255232, 91035243, 1689724, 1724280, 2843510, 3138232; Product type c : carrier; cytochrome d terminal oxidase subunit I complement(2424766..2426334) Escherichia fergusonii ATCC 35469 7122840 YP_002383486.1 CDS mngB NC_011740.1 2427185 2429818 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14645248, 9063979; Product type e : enzyme; alpha-mannosidase complement(2427185..2429818) Escherichia fergusonii ATCC 35469 7122839 YP_002383487.1 CDS mngA NC_011740.1 2429838 2431766 R involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC complement(2429838..2431766) Escherichia fergusonii ATCC 35469 7120942 YP_002383488.1 CDS mngR NC_011740.1 2431924 2432643 D regulates the succiny-lCoA synthetase operon; DNA-binding transcriptional repressor MngR 2431924..2432643 Escherichia fergusonii ATCC 35469 7120941 YP_002383489.1 CDS EFER_2375 NC_011740.1 2433018 2433518 D converts methylaspartate to L-glutamate; methylaspartate mutase subunit S 2433018..2433518 Escherichia fergusonii ATCC 35469 7120943 YP_002383490.1 CDS EFER_2376 NC_011740.1 2433518 2434906 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; glutamate mutase L 2433518..2434906 Escherichia fergusonii ATCC 35469 7123943 YP_002383491.1 CDS EFER_2377 NC_011740.1 2434925 2436370 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; methylaspartate mutase subunit E 2434925..2436370 Escherichia fergusonii ATCC 35469 7121891 YP_002383492.1 CDS EFER_2378 NC_011740.1 2436371 2437612 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; methylaspartate ammonia-lyase 2436371..2437612 Escherichia fergusonii ATCC 35469 7121892 YP_002383493.1 CDS EFER_2379 NC_011740.1 2437616 2438986 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11748244; Product type pe : enzyme; 3-methylaspartate ammonia-lyase, glutamate mutase 2437616..2438986 Escherichia fergusonii ATCC 35469 7123944 YP_002383494.1 CDS EFER_2380 NC_011740.1 2438983 2439300 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2438983..2439300 Escherichia fergusonii ATCC 35469 7121893 YP_002383495.1 CDS EFER_2381 NC_011740.1 2439360 2440724 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; symport protein 2439360..2440724 Escherichia fergusonii ATCC 35469 7121894 YP_002383496.1 CDS EFER_2382 NC_011740.1 2440787 2442439 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; Fumarate hydratase class I subunit beta 2440787..2442439 Escherichia fergusonii ATCC 35469 7123945 YP_002383497.1 CDS EFER_2383 NC_011740.1 2442447 2443370 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; LysR-like transcriptional regulator complement(2442447..2443370) Escherichia fergusonii ATCC 35469 7121895 YP_002383498.1 CDS sucD NC_011740.1 2443702 2444571 R Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha complement(2443702..2444571) Escherichia fergusonii ATCC 35469 7123280 YP_002383499.1 CDS sucC NC_011740.1 2444571 2445737 R catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta complement(2444571..2445737) Escherichia fergusonii ATCC 35469 7121957 YP_002383500.1 CDS sucB NC_011740.1 2445831 2447048 R component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase complement(2445831..2447048) Escherichia fergusonii ATCC 35469 7121955 YP_002383501.1 CDS sucA NC_011740.1 2447063 2449864 R SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component complement(2447063..2449864) Escherichia fergusonii ATCC 35469 7123953 YP_002383502.1 CDS sdhB NC_011740.1 2450120 2450836 R part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit complement(2450120..2450836) Escherichia fergusonii ATCC 35469 7123402 YP_002383503.1 CDS sdhA NC_011740.1 2450852 2452618 R part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit complement(2450852..2452618) Escherichia fergusonii ATCC 35469 7121756 YP_002383504.1 CDS sdhD NC_011740.1 2452618 2452965 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 82124790, 89076355, 9521736, 99414342, 6383359; Product type m : membrane component; succinate dehydrogenase cytochrome b556 small membrane subunit complement(2452618..2452965) Escherichia fergusonii ATCC 35469 7123371 YP_002383505.1 CDS sdhC NC_011740.1 2452959 2453348 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6237244, 89076355, 89123360, 9521736, 99414342, 11259408, 3309132, 6383359, 9822661; Product type m : membrane component; succinate dehydrogenase cytochrome b556 large membrane subunit complement(2452959..2453348) Escherichia fergusonii ATCC 35469 7121758 YP_002383506.1 CDS EFER_2392 NC_011740.1 2453400 2453621 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2453400..2453621 Escherichia fergusonii ATCC 35469 7121757 YP_002383507.1 CDS EFER_2393 NC_011740.1 2453688 2453855 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2453688..2453855 Escherichia fergusonii ATCC 35469 7123390 YP_002383508.1 CDS gltA NC_011740.1 2454057 2455340 D type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 2454057..2455340 Escherichia fergusonii ATCC 35469 7121897 YP_002383509.1 CDS EFER_2395 NC_011740.1 2455493 2455651 R Evidence 6 : Doubtful CDS; hypothetical protein complement(2455493..2455651) Escherichia fergusonii ATCC 35469 7120582 YP_002383510.1 CDS EFER_2396 NC_011740.1 2455897 2456460 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; fimbrial-like adhesin protein 2455897..2456460 Escherichia fergusonii ATCC 35469 7121898 YP_002383511.1 CDS ybgQ NC_011740.1 2456432 2458969 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2456432..2458969 Escherichia fergusonii ATCC 35469 7123391 YP_002383512.1 CDS EFER_2398 NC_011740.1 2458960 2459715 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; protein, chaperone 2458960..2459715 Escherichia fergusonii ATCC 35469 7122083 YP_002383513.1 CDS ybgO NC_011740.1 2459712 2460773 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2459712..2460773 Escherichia fergusonii ATCC 35469 7121899 YP_002383514.1 CDS abrB NC_011740.1 2460847 2461968 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8002588; Product type ph : phenotype; hypothetical protein 2460847..2461968 Escherichia fergusonii ATCC 35469 7122082 YP_002383515.1 CDS EFER_2401 NC_011740.1 2462026 2462670 R catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline; pyrrolidone-carboxylate peptidase complement(2462026..2462670) Escherichia fergusonii ATCC 35469 7124008 YP_002383516.1 CDS EFER_2402 NC_011740.1 2462680 2463675 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein complement(2462680..2463675) Escherichia fergusonii ATCC 35469 7123392 YP_002383517.1 CDS EFER_2403 NC_011740.1 2463672 2464460 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein complement(2463672..2464460) Escherichia fergusonii ATCC 35469 7121905 YP_002383518.1 CDS ybgL NC_011740.1 2464469 2465203 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1729609; Product type pe : enzyme; LamB/YcsF family protein complement(2464469..2465203) Escherichia fergusonii ATCC 35469 7121906 YP_002383519.1 CDS ybgK NC_011740.1 2465193 2466125 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hydrolase subunit complement(2465193..2466125) Escherichia fergusonii ATCC 35469 7122081 YP_002383520.1 CDS ybgJ NC_011740.1 2466119 2466775 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hydrolase subunit complement(2466119..2466775) Escherichia fergusonii ATCC 35469 7123423 YP_002383521.1 CDS ybgI NC_011740.1 2466798 2467541 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 14519207; hydrolase-oxidase complement(2466798..2467541) Escherichia fergusonii ATCC 35469 7122080 YP_002383522.1 CDS ybgH NC_011740.1 2467810 2469291 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15175316; Product type pt : transporter; transporter 2467810..2469291 Escherichia fergusonii ATCC 35469 7122079 YP_002383523.1 CDS phr NC_011740.1 2469334 2470752 R UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent; deoxyribodipyrimidine photolyase complement(2469334..2470752) Escherichia fergusonii ATCC 35469 7122078 YP_002383524.1 CDS ybgA NC_011740.1 2470749 2471258 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 6325460, 8387990; hypothetical protein complement(2470749..2471258) Escherichia fergusonii ATCC 35469 7122064 YP_002383525.1 CDS ybfA NC_011740.1 2471360 2471566 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2471360..2471566) Escherichia fergusonii ATCC 35469 7122074 YP_002383526.1 CDS kdpA NC_011740.1 2471968 2473641 D catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A 2471968..2473641 Escherichia fergusonii ATCC 35469 7123972 YP_002383527.1 CDS kdpB NC_011740.1 2473664 2475712 D One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit B 2473664..2475712 Escherichia fergusonii ATCC 35469 7120805 YP_002383528.1 CDS kdpC NC_011740.1 2475721 2476293 D One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex; potassium-transporting ATPase subunit C 2475721..2476293 Escherichia fergusonii ATCC 35469 7123758 YP_002383529.1 CDS kdpD NC_011740.1 2476286 2478970 D sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein; sensor protein KdpD 2476286..2478970 Escherichia fergusonii ATCC 35469 7123223 YP_002383530.1 CDS kdpE NC_011740.1 2478967 2479644 D response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport; DNA-binding transcriptional activator KdpE 2478967..2479644 Escherichia fergusonii ATCC 35469 7120806 YP_002383531.1 CDS EFER_2417 NC_011740.1 2479856 2480074 R Evidence 6 : Doubtful CDS; hypothetical protein complement(2479856..2480074) Escherichia fergusonii ATCC 35469 7120807 YP_002383532.1 CDS speF NC_011740.1 2480334 2482532 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92041955; Product type e : enzyme; ornithine decarboxylase 2480334..2482532 Escherichia fergusonii ATCC 35469 7123393 YP_002383533.1 CDS potE NC_011740.1 2482529 2483848 D catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system; putrescine transporter 2482529..2483848 Escherichia fergusonii ATCC 35469 7121806 YP_002383534.1 CDS pgm NC_011740.1 2484071 2485711 R catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase complement(2484071..2485711) Escherichia fergusonii ATCC 35469 7120102 YP_002383535.1 CDS seqA NC_011740.1 2485737 2486282 R negative modulator of the initiation of chromosome replication; replication initiation regulator SeqA complement(2485737..2486282) Escherichia fergusonii ATCC 35469 7122590 YP_002383536.1 CDS ybfF NC_011740.1 2486467 2487231 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15808744; Product type pe : enzyme; hypothetical protein 2486467..2487231 Escherichia fergusonii ATCC 35469 7121768 YP_002383537.1 CDS ybfE NC_011740.1 2487371 2487664 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20223640, 12427949; Product type cp : cell process; LexA regulated protein 2487371..2487664 Escherichia fergusonii ATCC 35469 7122071 YP_002383538.1 CDS fldA NC_011740.1 2487804 2488334 D An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA 2487804..2488334 Escherichia fergusonii ATCC 35469 7123973 YP_002383539.1 CDS EFER_2425 NC_011740.1 2488324 2488578 R Evidence 6 : Doubtful CDS; hypothetical protein complement(2488324..2488578) Escherichia fergusonii ATCC 35469 7124135 YP_002383540.1 CDS fur NC_011740.1 2488623 2489069 D negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; ferric uptake regulator 2488623..2489069 Escherichia fergusonii ATCC 35469 7121907 YP_002383541.1 CDS ybfN NC_011740.1 2489153 2489479 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; lipoprotein complement(2489153..2489479) Escherichia fergusonii ATCC 35469 7120156 YP_002383542.1 CDS ybfM NC_011740.1 2489529 2490935 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2118530, 9636669; Product type pt : transporter; outer membrane porin complement(2489529..2490935) Escherichia fergusonii ATCC 35469 7122073 YP_002383543.1 CDS glnS NC_011740.1 2491385 2493049 R catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase complement(2491385..2493049) Escherichia fergusonii ATCC 35469 7122072 YP_002383544.1 CDS nagE NC_011740.1 2493252 2495198 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system N-acetyl glucosamine specific transporter subunit IIABC complement(2493252..2495198) Escherichia fergusonii ATCC 35469 7120202 YP_002383545.1 CDS nagB NC_011740.1 2495531 2496331 D catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate; glucosamine-6-phosphate deaminase 2495531..2496331 Escherichia fergusonii ATCC 35469 7123733 YP_002383546.1 CDS nagA NC_011740.1 2496392 2497540 D catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate; N-acetylglucosamine-6-phosphate deacetylase 2496392..2497540 Escherichia fergusonii ATCC 35469 7123731 YP_002383547.1 CDS nagC NC_011740.1 2497549 2498769 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15066032, 90136533, 91171292, 92114782, 92356048, 2190615, 2668691, 7545108; Product type r : regulator; DNA-binding transcriptional dual regulator 2497549..2498769 Escherichia fergusonii ATCC 35469 7120662 YP_002383548.1 CDS nagD NC_011740.1 2498817 2499569 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16430214, 89343637; Product type e : enzyme; UMP phosphatase 2498817..2499569 Escherichia fergusonii ATCC 35469 7123732 YP_002383549.1 CDS asnB NC_011740.1 2499826 2501490 D functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP; asparagine synthetase B 2499826..2501490 Escherichia fergusonii ATCC 35469 7120663 YP_002383550.1 CDS EFER_2436 NC_011740.1 2501532 2501969 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2501532..2501969) Escherichia fergusonii ATCC 35469 7120568 YP_002383551.1 CDS EFER_2439 NC_011740.1 2503194 2503778 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 2503194..2503778 Escherichia fergusonii ATCC 35469 7120043 YP_002383552.1 CDS ubiF NC_011740.1 2503785 2504960 R catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase complement(2503785..2504960) Escherichia fergusonii ATCC 35469 7121909 YP_002383553.1 CDS miaB NC_011740.1 2505106 2506530 D catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 2505106..2506530 Escherichia fergusonii ATCC 35469 7122620 YP_002383554.1 CDS ybeZ NC_011740.1 2506644 2507723 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12762842; Product type pe : enzyme; hypothetical protein 2506644..2507723 Escherichia fergusonii ATCC 35469 7123243 YP_002383555.1 CDS ybeY NC_011740.1 2507720 2508187 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16511207; Product type pe : enzyme; metalloprotease 2507720..2508187 Escherichia fergusonii ATCC 35469 7122070 YP_002383556.1 CDS ybeX NC_011740.1 2508277 2509155 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1779764; Product type pt : transporter; divalent ion export protein 2508277..2509155 Escherichia fergusonii ATCC 35469 7122069 YP_002383557.1 CDS lnt NC_011740.1 2509180 2510718 D Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 2509180..2510718 Escherichia fergusonii ATCC 35469 7122068 YP_002383558.1 CDS EFER_2446 NC_011740.1 2510750 2510914 R Evidence 6 : Doubtful CDS; hypothetical protein complement(2510750..2510914) Escherichia fergusonii ATCC 35469 7123762 YP_002383559.1 CDS EFER_2447 NC_011740.1 2510850 2512787 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2510850..2512787) Escherichia fergusonii ATCC 35469 7121910 YP_002383560.1 CDS gltI NC_011740.1 2513183 2514091 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1091636, 1091635, 10493123, 8740179, 10972807; Product type t : transporter; glutamate and aspartate transporter subunit 2513183..2514091 Escherichia fergusonii ATCC 35469 7121911 YP_002383561.1 CDS gltJ NC_011740.1 2514261 2515001 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11121068; Product type t : transporter; glutamate and aspartate ABC transporter membrane protein 2514261..2515001 Escherichia fergusonii ATCC 35469 7120584 YP_002383562.1 CDS gltK NC_011740.1 2515001 2515675 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11121068; Product type t : transporter; glutamate and aspartate ABC transporter membrane protein 2515001..2515675 Escherichia fergusonii ATCC 35469 7123721 YP_002383563.1 CDS gltL NC_011740.1 2515675 2516400 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11121068; Product type t : transporter; glutamate and aspartate ABC transporter ATP-binding protein 2515675..2516400 Escherichia fergusonii ATCC 35469 7120585 YP_002383564.1 CDS rihA NC_011740.1 2516518 2517453 D Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific; ribonucleoside hydrolase 1 2516518..2517453 Escherichia fergusonii ATCC 35469 7120586 YP_002383565.1 CDS hscC NC_011740.1 2517537 2519207 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12183460, 14734171, 22055095, 9735342; Product type f : factor; Hsp70 family chaperone Hsc62, binds to RpoD and inhibits transcription 2517537..2519207 Escherichia fergusonii ATCC 35469 7123862 YP_002383566.1 CDS djlC NC_011740.1 2519267 2520718 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12183460, 12054669; Product type f : factor; Hsc56 co-chaperone of HscC complement(2519267..2520718) Escherichia fergusonii ATCC 35469 7122223 YP_002383567.1 CDS ybeU NC_011740.1 2520715 2521422 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2520715..2521422) Escherichia fergusonii ATCC 35469 7124122 YP_002383568.1 CDS ybeT NC_011740.1 2521524 2522078 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2521524..2522078 Escherichia fergusonii ATCC 35469 7122067 YP_002383569.1 CDS insF NC_011740.1 2523002 2523868 R Evidence 1b : Function experimentally demonstrated in the studied species; Product type h : extrachromosomal origin; IS3 element protein InsF complement(2523002..2523868) Escherichia fergusonii ATCC 35469 7122902 YP_002383570.1 CDS insE NC_011740.1 2523865 2524173 R Evidence 1b : Function experimentally demonstrated in the studied species; Product type h : extrachromosomal origin; IS3 element protein InsE complement(2523865..2524173) Escherichia fergusonii ATCC 35469 7120742 YP_002383571.1 CDS ybeR NC_011740.1 2524774 2525481 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2524774..2525481) Escherichia fergusonii ATCC 35469 7122903 YP_002383572.1 CDS ybeQ NC_011740.1 2525645 2526622 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2525645..2526622 Escherichia fergusonii ATCC 35469 7122066 YP_002383573.1 CDS ybeL NC_011740.1 2526692 2527174 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11373298, 12105207, 3320963, 7567469; hypothetical protein complement(2526692..2527174) Escherichia fergusonii ATCC 35469 7122065 YP_002383574.1 CDS leuS NC_011740.1 2527409 2529991 D leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 2527409..2529991 Escherichia fergusonii ATCC 35469 7122063 YP_002383575.1 CDS rlpB NC_011740.1 2530006 2530587 D rare lipoprotein B; involved in the assembly of LPS in the outer membrane; LPS-assembly lipoprotein RlpB 2530006..2530587 Escherichia fergusonii ATCC 35469 7120828 YP_002383576.1 CDS holA NC_011740.1 2530587 2531618 D required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 2530587..2531618 Escherichia fergusonii ATCC 35469 7121416 YP_002383577.1 CDS nadD NC_011740.1 2531622 2532263 D transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 2531622..2532263 Escherichia fergusonii ATCC 35469 7122208 YP_002383578.1 CDS ybeB NC_011740.1 2532522 2532839 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2532522..2532839 Escherichia fergusonii ATCC 35469 7120660 YP_002383579.1 CDS ybeA NC_011740.1 2532843 2533310 D SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 2532843..2533310 Escherichia fergusonii ATCC 35469 7121099 YP_002383580.1 CDS mrdA NC_011740.1 2533341 2535242 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86196149, 87030266, 89174517, 2644207; Product type e : enzyme; penicillin-binding protein 2 2533341..2535242 Escherichia fergusonii ATCC 35469 7121098 YP_002383581.1 CDS mrdB NC_011740.1 2535245 2536357 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89123070, 90036736, 91072213, 3316191; Product type cp : cell process; cell wall shape-determining protein 2535245..2536357 Escherichia fergusonii ATCC 35469 7120965 YP_002383582.1 CDS rlpA NC_011740.1 2536308 2537456 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88058785, 2644207; Product type lp : lipoprotein; rare lipoprotein A 2536308..2537456 Escherichia fergusonii ATCC 35469 7123250 YP_002383583.1 CDS dacA NC_011740.1 2537597 2538808 D penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; D-alanyl-D-alanine carboxypeptidase 2537597..2538808 Escherichia fergusonii ATCC 35469 7121415 YP_002383584.1 CDS ybeD NC_011740.1 2538914 2539177 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8444795; hypothetical protein 2538914..2539177 Escherichia fergusonii ATCC 35469 7122860 YP_002383585.1 CDS lipB NC_011740.1 2539278 2539928 D lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 2539278..2539928 Escherichia fergusonii ATCC 35469 7123807 YP_002383586.1 CDS lipA NC_011740.1 2540107 2541072 D catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 2540107..2541072 Escherichia fergusonii ATCC 35469 7120835 YP_002383587.1 CDS tatE NC_011740.1 2541186 2541404 R TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein E complement(2541186..2541404) Escherichia fergusonii ATCC 35469 7123761 YP_002383588.1 CDS EFER_2478 NC_011740.1 2541518 2542381 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hydrolase complement(2541518..2542381) Escherichia fergusonii ATCC 35469 7123957 YP_002383589.1 CDS crcB NC_011740.1 2542398 2542781 D may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 2542398..2542781 Escherichia fergusonii ATCC 35469 7123394 YP_002383590.1 CDS cspE NC_011740.1 2542835 2543044 R member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator; cold shock protein CspE complement(2542835..2543044) Escherichia fergusonii ATCC 35469 7122801 YP_002383591.1 CDS pagP NC_011740.1 2543230 2543814 R catalyzes the transfer of palmitate to lipid A; palmitoyl transferase complement(2543230..2543814) Escherichia fergusonii ATCC 35469 7122821 YP_002383592.1 CDS dcuC NC_011740.1 2544237 2545625 D responsible for the transport of C4-dicarboxylates during anaerobic growth; C4-dicarboxylate transporter DcuC 2544237..2545625 Escherichia fergusonii ATCC 35469 7121912 YP_002383593.1 CDS rna NC_011740.1 2545854 2546666 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90151658, 90264307, 2253883, 8188249; Product type e : enzyme; ribonuclease I 2545854..2546666 Escherichia fergusonii ATCC 35469 7122877 YP_002383594.1 CDS rnk NC_011740.1 2546865 2547275 D Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator 2546865..2547275 Escherichia fergusonii ATCC 35469 7121421 YP_002383595.1 CDS uspG NC_011740.1 2547634 2548062 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12732303, 12071968; Product type f : factor; universal stress protein UP12 2547634..2548062 Escherichia fergusonii ATCC 35469 7121429 YP_002383596.1 CDS ahpF NC_011740.1 2548184 2549749 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89197774, 1592833; Product type e : enzyme; alkyl hydroperoxide reductase F52a subunit complement(2548184..2549749) Escherichia fergusonii ATCC 35469 7122644 YP_002383597.1 CDS ahpC NC_011740.1 2549920 2550483 R with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate; alkyl hydroperoxide reductase subunit C complement(2549920..2550483) Escherichia fergusonii ATCC 35469 7124014 YP_002383598.1 CDS dsbG NC_011740.1 2550796 2551602 D Involved in disulfide bond formation; disulfide isomerase/thiol-disulfide oxidase 2550796..2551602 Escherichia fergusonii ATCC 35469 7124013 YP_002383599.1 CDS EFER_2490 NC_011740.1 2551769 2552740 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; HTH-type transcriptional regulator ybdO 2551769..2552740 Escherichia fergusonii ATCC 35469 7122923 YP_002383600.1 CDS ibrA NC_011740.1 2552809 2554059 D Evidence 2b : Function of strongly homologous gene; PubMedId : 12057959; Product type r : regulator; immunoglobulin-binding regulator 2552809..2554059 Escherichia fergusonii ATCC 35469 7121913 YP_002383601.1 CDS ibrB NC_011740.1 2554056 2554673 D Evidence 2b : Function of strongly homologous gene; PubMedId : 12057959; Product type r : regulator; immunoglobulin-binding regulator 2554056..2554673 Escherichia fergusonii ATCC 35469 7120720 YP_002383602.1 CDS ybdL NC_011740.1 2554674 2555834 R catalyzes the transfer of an amino moiety; aminotransferase complement(2554674..2555834) Escherichia fergusonii ATCC 35469 7120721 YP_002383603.1 CDS ybdH NC_011740.1 2555943 2557031 D member of the iron-containing alcohol dehydrogenase family; unknown function; hypothetical protein 2555943..2557031 Escherichia fergusonii ATCC 35469 7121097 YP_002383604.1 CDS ybdD NC_011740.1 2557041 2557238 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2557041..2557238) Escherichia fergusonii ATCC 35469 7121095 YP_002383605.1 CDS cstA NC_011740.1 2557366 2559471 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91162636, 2521622; Product type pf : factor; carbon starvation protein complement(2557366..2559471) Escherichia fergusonii ATCC 35469 7121092 YP_002383606.1 CDS ybdB NC_011740.1 2559652 2560065 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2521621, 2521622, 15808744; Product type pe : enzyme; hypothetical protein complement(2559652..2560065) Escherichia fergusonii ATCC 35469 7124109 YP_002383607.1 CDS entA NC_011740.1 2560068 2560814 R catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase complement(2560068..2560814) Escherichia fergusonii ATCC 35469 7121091 YP_002383608.1 CDS entB NC_011740.1 2560814 2561671 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20183918, 90241937, 91035252, 9485415, 97361959, 2521621, 2521622; Product type e : enzyme; isochorismatase complement(2560814..2561671) Escherichia fergusonii ATCC 35469 7122950 YP_002383609.1 CDS entE NC_011740.1 2561685 2563295 R bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E complement(2561685..2563295) Escherichia fergusonii ATCC 35469 7122951 YP_002383610.1 CDS entC NC_011740.1 2563305 2564480 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89123153, 90165423, 90241936, 2110093, 2139473; Product type e : enzyme; isochorismate synthase 1 complement(2563305..2564480) Escherichia fergusonii ATCC 35469 7122952 YP_002383611.1 CDS fepB NC_011740.1 2564669 2565625 D with FepCDG is involved in the transport of ferric enterobactin; iron-enterobactin transporter periplasmic binding protein 2564669..2565625 Escherichia fergusonii ATCC 35469 7123561 YP_002383612.1 CDS ybdA NC_011740.1 2565629 2566879 R protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters; enterobactin exporter EntS complement(2565629..2566879) Escherichia fergusonii ATCC 35469 7120006 YP_002383613.1 CDS fepD NC_011740.1 2566990 2567994 D with FepBCG is involved in the transport of ferric enterobactin; iron-enterobactin transporter membrane protein 2566990..2567994 Escherichia fergusonii ATCC 35469 7121090 YP_002383614.1 CDS fepG NC_011740.1 2567991 2568983 D with FepBCD is involved in the transport of ferric enterobactin; iron-enterobactin transporter permease 2567991..2568983 Escherichia fergusonii ATCC 35469 7123088 YP_002383615.1 CDS fepC NC_011740.1 2568662 2569780 D with FepBDE is involved in the transport of ferric enterobactin; iron-enterobactin transporter ATP-binding protein 2568662..2569780 Escherichia fergusonii ATCC 35469 7120007 YP_002383616.1 CDS EFER_2507 NC_011740.1 2569815 2570990 R part of the ferric enterobactin transport system; necessary for enetrobactin uptake; ferric enterobactin transport protein FepE complement(2569815..2570990) Escherichia fergusonii ATCC 35469 7123087 YP_002383617.1 CDS entF NC_011740.1 2571200 2575081 R with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin; enterobactin synthase subunit F complement(2571200..2575081) Escherichia fergusonii ATCC 35469 7123395 YP_002383618.1 CDS ybdZ NC_011740.1 2575078 2575302 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2575078..2575302) Escherichia fergusonii ATCC 35469 7124133 YP_002383619.1 CDS fes NC_011740.1 2575299 2576423 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92291125, 94198561, 2974033; Product type e : enzyme; enterobactin/ferric enterobactin esterase complement(2575299..2576423) Escherichia fergusonii ATCC 35469 7123806 YP_002383620.1 CDS fepA NC_011740.1 2576744 2578984 D Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space; outer membrane receptor FepA 2576744..2578984 Escherichia fergusonii ATCC 35469 7120008 YP_002383621.1 CDS EFER_2513 NC_011740.1 2579009 2579818 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 89313305, 90132534, 91035252, 8939709, 9214294; Product type e : enzyme; enterobactin synthase multienzyme complex phosphopantetheinyltransferase 2579009..2579818 Escherichia fergusonii ATCC 35469 7123361 YP_002383622.1 CDS EFER_2514 NC_011740.1 2579820 2580866 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; transketolase complement(2579820..2580866) Escherichia fergusonii ATCC 35469 7121914 YP_002383623.1 CDS EFER_2515 NC_011740.1 2580748 2581578 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 93374831, 8396116; Product type e : enzyme; transketolase N-terminal section (TK) complement(2580748..2581578) Escherichia fergusonii ATCC 35469 7121915 YP_002383624.1 CDS EFER_2516 NC_011740.1 2581941 2582891 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator 2581941..2582891 Escherichia fergusonii ATCC 35469 7123396 YP_002383625.1 CDS EFER_2517 NC_011740.1 2583242 2584762 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; glycerol kinase 2 2583242..2584762 Escherichia fergusonii ATCC 35469 7121916 YP_002383626.1 CDS EFER_2518 NC_011740.1 2584866 2585801 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; sugar ABC transporter substrate-binding protein 2584866..2585801 Escherichia fergusonii ATCC 35469 7121917 YP_002383627.1 CDS EFER_2519 NC_011740.1 2585812 2586468 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; lipoprotein 2585812..2586468 Escherichia fergusonii ATCC 35469 7121918 YP_002383628.1 CDS EFER_2520 NC_011740.1 2586470 2588014 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type t : transporter; transport system ATP-binding protein 2586470..2588014 Escherichia fergusonii ATCC 35469 7121919 YP_002383629.1 CDS EFER_2521 NC_011740.1 2588032 2589099 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transport system permease 2588032..2589099 Escherichia fergusonii ATCC 35469 7121920 YP_002383630.1 CDS EFER_2522 NC_011740.1 2589126 2589950 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; oxidoreductase 2589126..2589950 Escherichia fergusonii ATCC 35469 7121921 YP_002383631.1 CDS EFER_2523 NC_011740.1 2589950 2590768 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; short chain dehydrogenase 2589950..2590768 Escherichia fergusonii ATCC 35469 7121922 YP_002383632.1 CDS EFER_2524 NC_011740.1 2590942 2591175 R Evidence 6 : Doubtful CDS; hypothetical protein complement(2590942..2591175) Escherichia fergusonii ATCC 35469 7123948 YP_002383633.1 CDS EFER_2525 NC_011740.1 2591381 2591632 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10361310; Product type pm : membrane component; small toxic membrane polypeptide, HokE-like protein (partial) complement(2591381..2591632) Escherichia fergusonii ATCC 35469 7123397 YP_002383634.1 CDS EFER_2526 NC_011740.1 2591445 2591678 R Evidence 6 : Doubtful CDS; hypothetical protein complement(2591445..2591678) Escherichia fergusonii ATCC 35469 7121923 YP_002383635.1 CDS ybdK NC_011740.1 2591985 2593103 D ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity; carboxylate-amine ligase 2591985..2593103 Escherichia fergusonii ATCC 35469 7121924 YP_002383636.1 CDS ybdJ NC_011740.1 2593169 2593417 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2593169..2593417 Escherichia fergusonii ATCC 35469 7121096 YP_002383637.1 CDS ybdF NC_011740.1 2593482 2593850 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2593482..2593850 Escherichia fergusonii ATCC 35469 7123805 YP_002383638.1 CDS nfnB NC_011740.1 2593945 2594598 D catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase 2593945..2594598 Escherichia fergusonii ATCC 35469 7121093 YP_002383639.1 CDS ybdG NC_011740.1 2594706 2595953 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; membrane protein 2594706..2595953 Escherichia fergusonii ATCC 35469 7120686 YP_002383640.1 CDS pheP NC_011740.1 2596033 2597409 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91267923, 94042931, 8626334; Product type t : transporter; phenylalanine transporter complement(2596033..2597409) Escherichia fergusonii ATCC 35469 7121094 YP_002383641.1 CDS cusA NC_011740.1 2597511 2600654 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20461235, 21125583, 21178899, 21450803, 11399769, 12813074, 1711024, 7984428; Product type t : transporter; copper/silver efflux system, membrane component complement(2597511..2600654) Escherichia fergusonii ATCC 35469 7122594 YP_002383642.1 CDS EFER_2535 NC_011740.1 2600557 2600712 R Evidence 6 : Doubtful CDS; hypothetical protein complement(2600557..2600712) Escherichia fergusonii ATCC 35469 7124110 YP_002383643.1 CDS cusB NC_011740.1 2600666 2601889 R with CusA, CusC and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system membrane fusion protein CusB complement(2600666..2601889) Escherichia fergusonii ATCC 35469 7123398 YP_002383644.1 CDS cusF NC_011740.1 2601905 2602237 R Evidence 2b : Function of strongly homologous gene; PubMedId : 21125583, 11283292, 11399769, 12813074; Product type f : factor; copper-binding protein complement(2601905..2602237) Escherichia fergusonii ATCC 35469 7122828 YP_002383645.1 CDS cusC NC_011740.1 2602260 2603648 R with CusA, CusB and CusF is part of a cation efflux system that mediates resistance to copper and silver; copper/silver efflux system outer membrane protein CusC complement(2602260..2603648) Escherichia fergusonii ATCC 35469 7124111 YP_002383646.1 CDS cusR NC_011740.1 2603799 2604482 D response regulator in two-component regulatory system with CusS; regulates the copper efflux system; DNA-binding transcriptional activator CusR 2603799..2604482 Escherichia fergusonii ATCC 35469 7122829 YP_002383647.1 CDS cusS NC_011740.1 2604460 2605920 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20461235, 11283292, 11399769; Product type r : regulator; sensor kinase CusS 2604460..2605920 Escherichia fergusonii ATCC 35469 7122830 YP_002383648.1 CDS EFER_2542 NC_011740.1 2606136 2606615 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2606136..2606615 Escherichia fergusonii ATCC 35469 7122831 YP_002383649.1 CDS EFER_2543 NC_011740.1 2606809 2607099 D Evidence 6 : Doubtful CDS; hypothetical protein 2606809..2607099 Escherichia fergusonii ATCC 35469 7121925 YP_002383650.1 CDS htpG NC_011740.1 2607657 2609531 R molecular chaperone; heat shock protein 90 complement(2607657..2609531) Escherichia fergusonii ATCC 35469 7121926 YP_002383651.1 CDS recR NC_011740.1 2609641 2610246 R involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR complement(2609641..2610246) Escherichia fergusonii ATCC 35469 7122231 YP_002383652.1 CDS ybaB NC_011740.1 2610246 2610575 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 15322138, 1698765, 2674903; hypothetical protein complement(2610246..2610575) Escherichia fergusonii ATCC 35469 7121384 YP_002383653.1 CDS dnaX NC_011740.1 2610628 2612559 R catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau complement(2610628..2612559) Escherichia fergusonii ATCC 35469 7121064 YP_002383654.1 CDS apt NC_011740.1 2612688 2613239 R catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase complement(2612688..2613239) Escherichia fergusonii ATCC 35469 7124126 YP_002383655.1 CDS ybaN NC_011740.1 2613401 2613769 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(2613401..2613769) Escherichia fergusonii ATCC 35469 7120525 YP_002383656.1 CDS priC NC_011740.1 2613839 2614366 D PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks; primosomal replication protein N'' 2613839..2614366 Escherichia fergusonii ATCC 35469 7123261 YP_002383657.1 CDS ybaM NC_011740.1 2614380 2614544 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2614380..2614544 Escherichia fergusonii ATCC 35469 7120127 YP_002383658.1 CDS kefA NC_011740.1 2614583 2617942 R small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS; potassium efflux protein KefA complement(2614583..2617942) Escherichia fergusonii ATCC 35469 7121067 YP_002383659.1 CDS acrR NC_011740.1 2618068 2618715 R regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine; DNA-binding transcriptional repressor AcrR complement(2618068..2618715) Escherichia fergusonii ATCC 35469 7120811 YP_002383660.1 CDS acrA NC_011740.1 2618859 2620052 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15155734, 21450803, 383699, 390095, 94012493, 10920254, 7651136; Product type t : transporter; multidrug efflux system 2618859..2620052 Escherichia fergusonii ATCC 35469 7122270 YP_002383661.1 CDS acrB NC_011740.1 2620075 2623224 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12351840, 12654283, 15111118, 15155734, 21450803, 94012493, 10920254, 7651136; Product type t : transporter; multidrug efflux system protein 2620075..2623224 Escherichia fergusonii ATCC 35469 7122265 YP_002383662.1 CDS ybaJ NC_011740.1 2623727 2624101 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1956303, 7984428, 14645275; hypothetical protein 2623727..2624101 Escherichia fergusonii ATCC 35469 7122266 YP_002383663.1 CDS hha NC_011740.1 2624128 2624346 D with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins; hemolysin expression-modulating protein 2624128..2624346 Escherichia fergusonii ATCC 35469 7121065 YP_002383664.1 CDS ylaC NC_011740.1 2624819 2625313 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2624819..2625313 Escherichia fergusonii ATCC 35469 7122193 YP_002383665.1 CDS EFER_2559 NC_011740.1 2625452 2627002 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2625452..2627002 Escherichia fergusonii ATCC 35469 7122042 YP_002383666.1 CDS ybaA NC_011740.1 2627044 2627397 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2627044..2627397) Escherichia fergusonii ATCC 35469 7121927 YP_002383667.1 CDS EFER_2561 NC_011740.1 2627545 2627727 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2627545..2627727) Escherichia fergusonii ATCC 35469 7120010 YP_002383668.1 CDS ybaZ NC_011740.1 2627698 2628087 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; methylated DNA-protein cysteine alkyltransferase 2627698..2628087 Escherichia fergusonii ATCC 35469 7121928 YP_002383669.1 CDS insG NC_011740.1 2628188 2629516 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; IS4 transposase; KpLE2 phage-like element 2628188..2629516 Escherichia fergusonii ATCC 35469 7121074 YP_002383670.1 CDS ybaY NC_011740.1 2629556 2630128 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; lipoprotein complement(2629556..2630128) Escherichia fergusonii ATCC 35469 7120745 YP_002383671.1 CDS tesB NC_011740.1 2630346 2631206 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86139906, 91250410, 10876240; Product type e : enzyme; acyl-CoA thioesterase II 2630346..2631206 Escherichia fergusonii ATCC 35469 7121073 YP_002383672.1 CDS amtB NC_011740.1 2631255 2632541 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 22020597, 9618533, 10931328, 1645722, 7984428; Product type t : transporter; ammonium transporter complement(2631255..2632541) Escherichia fergusonii ATCC 35469 7121986 YP_002383673.1 CDS glnK NC_011740.1 2632571 2632909 R indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia.; nitrogen regulatory protein P-II 2 complement(2632571..2632909) Escherichia fergusonii ATCC 35469 7123712 YP_002383674.1 CDS mdlB NC_011740.1 2633090 2634871 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 94124004; Product type pt : transporter; multidrug transporter membrane protein/ATP-binding protein complement(2633090..2634871) Escherichia fergusonii ATCC 35469 7120198 YP_002383675.1 CDS mdlA NC_011740.1 2634864 2636636 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 94124004, 10850996; Product type pt : transporter; multidrug transporter membrane protein/ATP-binding protein complement(2634864..2636636) Escherichia fergusonii ATCC 35469 7121242 YP_002383676.1 CDS ybaO NC_011740.1 2636666 2637124 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7904973, 10850996; Product type pr : regulator; DNA-binding transcriptional regulator complement(2636666..2637124) Escherichia fergusonii ATCC 35469 7121241 YP_002383677.1 CDS cof NC_011740.1 2637277 2638095 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15292217; Product type e : enzyme; thiamin pyrimidine pyrophosphate hydrolase complement(2637277..2638095) Escherichia fergusonii ATCC 35469 7121068 YP_002383678.1 CDS ybaE NC_011740.1 2638195 2639895 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2638195..2639895 Escherichia fergusonii ATCC 35469 7122792 YP_002383679.1 CDS queC NC_011740.1 2639960 2640655 D YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His; queuosine biosynthesis protein QueC 2639960..2640655 Escherichia fergusonii ATCC 35469 7123260 YP_002383680.1 CDS ybaW NC_011740.1 2640707 2641105 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2640707..2641105) Escherichia fergusonii ATCC 35469 7122342 YP_002383681.1 CDS ybaV NC_011740.1 2641211 2641654 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2641211..2641654) Escherichia fergusonii ATCC 35469 7121072 YP_002383682.1 CDS ppiD NC_011740.1 2641735 2643651 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9670013; Product type e : enzyme; peptidyl-prolyl cis-trans isomerase complement(2641735..2643651) Escherichia fergusonii ATCC 35469 7123263 YP_002383683.1 CDS hupB NC_011740.1 2643798 2644070 R histone-like DNA-binding protein; transcriptional regulator HU subunit beta complement(2643798..2644070) Escherichia fergusonii ATCC 35469 7120114 YP_002383684.1 CDS lon NC_011740.1 2644280 2646634 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10094703, 14665623, 8939438, 91072263, 97137085, 2984174, 3042779, 3289547, 7988699, 8226758, 8294008; Product type e : enzyme; DNA-binding ATP-dependent protease La complement(2644280..2646634) Escherichia fergusonii ATCC 35469 7124004 YP_002383685.1 CDS clpX NC_011740.1 2646821 2648095 R binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX complement(2646821..2648095) Escherichia fergusonii ATCC 35469 7123381 YP_002383686.1 CDS clpP NC_011740.1 2648221 2648844 R hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit complement(2648221..2648844) Escherichia fergusonii ATCC 35469 7120904 YP_002383687.1 CDS tig NC_011740.1 2649089 2650387 R Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor complement(2649089..2650387) Escherichia fergusonii ATCC 35469 7120903 YP_002383688.1 CDS bolA NC_011740.1 2650728 2651045 R positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress; transcriptional regulator BolA complement(2650728..2651045) Escherichia fergusonii ATCC 35469 7122132 YP_002383689.1 CDS yajG NC_011740.1 2651348 2651926 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; hypothetical protein 2651348..2651926 Escherichia fergusonii ATCC 35469 7121676 YP_002383690.1 CDS ampG NC_011740.1 2651970 2653445 D in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein; muropeptide transporter 2651970..2653445 Escherichia fergusonii ATCC 35469 7121059 YP_002383691.1 CDS cyoA NC_011740.1 2654088 2655035 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92112945, 92371427, 9378722, 98021084, 11017202, 1322173, 2162835, 2162837, 2165491, 2168206, 8231804, 8618822; Product type c : carrier; cytochrome o ubiquinol oxidase subunit II 2654088..2655035 Escherichia fergusonii ATCC 35469 7120514 YP_002383692.1 CDS cyoB NC_011740.1 2655057 2657048 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90330636, 92345252, 93349845, 9378722, 98021084, 11017202, 2162835, 2168206; Product type c : carrier; cytochrome o ubiquinol oxidase subunit I 2655057..2657048 Escherichia fergusonii ATCC 35469 7122842 YP_002383693.1 CDS cyoC NC_011740.1 2657038 2657652 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90330636, 92345252, 93349845, 9378722, 98021084, 11017202, 2162835, 2168206; Product type c : carrier; cytochrome o ubiquinol oxidase subunit III 2657038..2657652 Escherichia fergusonii ATCC 35469 7124112 YP_002383694.1 CDS cyoD NC_011740.1 2657652 2657981 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90330636, 90366572, 92345252, 9378722, 98021084, 11017202, 2162835; Product type c : carrier; cytochrome o ubiquinol oxidase subunit IV 2657652..2657981 Escherichia fergusonii ATCC 35469 7122843 YP_002383695.1 CDS cyoE NC_011740.1 2657993 2658883 D converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 2657993..2658883 Escherichia fergusonii ATCC 35469 7122844 YP_002383696.1 CDS EFER_2590 NC_011740.1 2659258 2660796 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2659258..2660796) Escherichia fergusonii ATCC 35469 7124113 YP_002383697.1 CDS EFER_2591 NC_011740.1 2660855 2661613 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; Regulatory proteins, IclR family complement(2660855..2661613) Escherichia fergusonii ATCC 35469 7121929 YP_002383698.1 CDS EFER_2592 NC_011740.1 2661723 2662586 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; shikimate dehydrogenase 2661723..2662586 Escherichia fergusonii ATCC 35469 7121930 YP_002383699.1 CDS EFER_2593 NC_011740.1 2662487 2664259 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; 3-oxosteroid 1-dehydrogenase 2662487..2664259 Escherichia fergusonii ATCC 35469 7121931 YP_002383700.1 CDS EFER_2594 NC_011740.1 2664213 2664593 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2664213..2664593 Escherichia fergusonii ATCC 35469 7123949 YP_002383701.1 CDS EFER_2595 NC_011740.1 2664604 2666307 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 2664604..2666307 Escherichia fergusonii ATCC 35469 7121932 YP_002383702.1 CDS EFER_2596 NC_011740.1 2666375 2667193 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2666375..2667193 Escherichia fergusonii ATCC 35469 7121933 YP_002383703.1 CDS EFER_2597 NC_011740.1 2667093 2668568 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; 4-hydroxybenzoate transporter 2667093..2668568 Escherichia fergusonii ATCC 35469 7123950 YP_002383704.1 CDS yajR NC_011740.1 2668721 2670085 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; MFS superfamily transporter 2668721..2670085 Escherichia fergusonii ATCC 35469 7121934 YP_002383705.1 CDS yajQ NC_011740.1 2670213 2670704 R nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; nucleotide-binding protein complement(2670213..2670704) Escherichia fergusonii ATCC 35469 7123259 YP_002383706.1 CDS panE NC_011740.1 2670872 2671783 D ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 2670872..2671783 Escherichia fergusonii ATCC 35469 7121062 YP_002383707.1 CDS yajL NC_011740.1 2671746 2672336 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 97039868, 99173753, 99311269; DJ-1 family protein 2671746..2672336 Escherichia fergusonii ATCC 35469 7122554 YP_002383708.1 CDS thiI NC_011740.1 2672390 2673838 R Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI complement(2672390..2673838) Escherichia fergusonii ATCC 35469 7123802 YP_002383709.1 CDS xseB NC_011740.1 2674044 2674286 D catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 2674044..2674286 Escherichia fergusonii ATCC 35469 7121994 YP_002383710.1 CDS ispA NC_011740.1 2674286 2675185 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89291702, 91210228; Product type e : enzyme; geranyltranstransferase 2674286..2675185 Escherichia fergusonii ATCC 35469 7122386 YP_002383711.1 CDS dxs NC_011740.1 2675210 2677072 D catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 2675210..2677072 Escherichia fergusonii ATCC 35469 7120790 YP_002383712.1 CDS yajO NC_011740.1 2677252 2678226 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15292217, 16077126; Product type e : enzyme; aldoketo-oxidoreductase 2677252..2678226 Escherichia fergusonii ATCC 35469 7123557 YP_002383713.1 CDS pgpA NC_011740.1 2678280 2678798 R hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate; phosphatidylglycerophosphatase A complement(2678280..2678798) Escherichia fergusonii ATCC 35469 7121061 YP_002383714.1 CDS thiL NC_011740.1 2678776 2679753 R catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine monophosphate kinase complement(2678776..2679753) Escherichia fergusonii ATCC 35469 7124068 YP_002383715.1 CDS nusB NC_011740.1 2679831 2680250 R Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB complement(2679831..2680250) Escherichia fergusonii ATCC 35469 7121996 YP_002383716.1 CDS ribH NC_011740.1 2680270 2680740 R RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase complement(2680270..2680740) Escherichia fergusonii ATCC 35469 7119685 YP_002383717.1 CDS ribD NC_011740.1 2680828 2681931 R riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase complement(2680828..2681931) Escherichia fergusonii ATCC 35469 7121408 YP_002383718.1 CDS nrdR NC_011740.1 2681935 2682384 R Evidence 2b : Function of strongly homologous gene; Product type r : regulator; transcriptional regulator NrdR complement(2681935..2682384) Escherichia fergusonii ATCC 35469 7121407 YP_002383719.1 CDS yajI NC_011740.1 2682475 2683077 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; hypothetical protein 2682475..2683077 Escherichia fergusonii ATCC 35469 7123028 YP_002383720.1 CDS tsx NC_011740.1 2683375 2684259 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91092502, 91358319, 93352541; Product type m : membrane component; nucleoside channel phage T6/colicin K receptor 2683375..2684259 Escherichia fergusonii ATCC 35469 7121060 YP_002383721.1 CDS yajD NC_011740.1 2684297 2684644 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2684297..2684644) Escherichia fergusonii ATCC 35469 7122176 YP_002383722.1 CDS secF NC_011740.1 2684773 2685744 R forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF complement(2684773..2685744) Escherichia fergusonii ATCC 35469 7123801 YP_002383723.1 CDS secD NC_011740.1 2685755 2687602 R part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD complement(2685755..2687602) Escherichia fergusonii ATCC 35469 7121763 YP_002383724.1 CDS yajC NC_011740.1 2687630 2687962 R member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC complement(2687630..2687962) Escherichia fergusonii ATCC 35469 7121761 YP_002383725.1 CDS tgt NC_011740.1 2687985 2689112 R Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase complement(2687985..2689112) Escherichia fergusonii ATCC 35469 7121058 YP_002383726.1 CDS queA NC_011740.1 2689167 2690237 R Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase complement(2689167..2690237) Escherichia fergusonii ATCC 35469 7121989 YP_002383727.1 CDS acpH NC_011740.1 2690330 2690911 D Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; acyl carrier protein phosphodiesterase 2690330..2690911 Escherichia fergusonii ATCC 35469 7122341 YP_002383728.1 CDS malZ NC_011740.1 2690916 2692733 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92184757, 1706703, 1918057; Product type e : enzyme; maltodextrin glucosidase complement(2690916..2692733) Escherichia fergusonii ATCC 35469 7122262 YP_002383729.1 CDS proY NC_011740.1 2692888 2694261 R cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation; proline-specific permease complement(2692888..2694261) Escherichia fergusonii ATCC 35469 7121229 YP_002383730.1 CDS brnQ NC_011740.1 2694338 2695657 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3078876, 6998958, 3550103, 7984428; Product type t : transporter; branched chain amino acid transporter complement(2694338..2695657) Escherichia fergusonii ATCC 35469 7120138 YP_002383731.1 CDS EFER_2625 NC_011740.1 2695649 2695849 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2695649..2695849 Escherichia fergusonii ATCC 35469 7121677 YP_002383732.1 CDS phoR NC_011740.1 2696062 2697357 R membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB; phosphate regulon sensor protein complement(2696062..2697357) Escherichia fergusonii ATCC 35469 7121935 YP_002383733.1 CDS phoB NC_011740.1 2697416 2698105 R two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB; transcriptional regulator PhoB complement(2697416..2698105) Escherichia fergusonii ATCC 35469 7122603 YP_002383734.1 CDS sbcD NC_011740.1 2698251 2699495 D with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity; exonuclease subunit SbcD 2698251..2699495 Escherichia fergusonii ATCC 35469 7122598 YP_002383735.1 CDS EFER_2629 NC_011740.1 2699492 2702635 D with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity; exonuclease subunit SbcC 2699492..2702635 Escherichia fergusonii ATCC 35469 7121194 YP_002383736.1 CDS mak NC_011740.1 2702752 2703804 R catalyzes phosphorylation of fructose; cytosolic enzyme; fructokinase complement(2702752..2703804) Escherichia fergusonii ATCC 35469 7121936 YP_002383737.1 CDS rdgC NC_011740.1 2703791 2704702 D Required for efficient pilin antigenic variation; recombination associated protein 2703791..2704702 Escherichia fergusonii ATCC 35469 7123286 YP_002383738.1 CDS yaiE NC_011740.1 2704741 2705025 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2704741..2705025) Escherichia fergusonii ATCC 35469 7122356 YP_002383739.1 CDS EFER_2633 NC_011740.1 2705096 2705773 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2705096..2705773) Escherichia fergusonii ATCC 35469 7121053 YP_002383740.1 CDS yaiA NC_011740.1 2706020 2706211 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2706020..2706211) Escherichia fergusonii ATCC 35469 7121937 YP_002383741.1 CDS aroL NC_011740.1 2706239 2706784 R type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase complement(2706239..2706784) Escherichia fergusonii ATCC 35469 7121051 YP_002383742.1 CDS yaiI NC_011740.1 2706960 2707424 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2706960..2707424) Escherichia fergusonii ATCC 35469 7120552 YP_002383743.1 CDS proC NC_011740.1 2707566 2708375 D catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 2707566..2708375 Escherichia fergusonii ATCC 35469 7121054 YP_002383744.1 CDS adrA NC_011740.1 2708391 2709590 R catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis; diguanylate cyclase AdrA complement(2708391..2709590) Escherichia fergusonii ATCC 35469 7123109 YP_002383745.1 CDS psiF NC_011740.1 2709611 2709931 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3533724, 2160940; Product type f : factor; hypothetical protein complement(2709611..2709931) Escherichia fergusonii ATCC 35469 7123799 YP_002383746.1 CDS phoA NC_011740.1 2710071 2711489 R Evidence 1b : Function experimentally demonstrated in the studied species; Product type e : enzyme; alkaline phosphatase complement(2710071..2711489) Escherichia fergusonii ATCC 35469 7124018 YP_002383747.1 CDS yaiB NC_011740.1 2711588 2711848 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2711588..2711848) Escherichia fergusonii ATCC 35469 7122597 YP_002383748.1 CDS ddlA NC_011740.1 2712312 2713406 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91129242, 92207163; Product type e : enzyme; D-alanine--D-alanine ligase 2712312..2713406 Escherichia fergusonii ATCC 35469 7121052 YP_002383749.1 CDS yaiZ NC_011740.1 2713430 2713642 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(2713430..2713642) Escherichia fergusonii ATCC 35469 7124119 YP_002383750.1 CDS EFER_2644 NC_011740.1 2713740 2714201 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 2713740..2714201 Escherichia fergusonii ATCC 35469 7121057 YP_002383751.1 CDS yaiW NC_011740.1 2714206 2715297 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; lipoprotein complement(2714206..2715297) Escherichia fergusonii ATCC 35469 7121938 YP_002383752.1 CDS sbmA NC_011740.1 2715309 2716529 R in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; transporter complement(2715309..2716529) Escherichia fergusonii ATCC 35469 7123800 YP_002383753.1 CDS ampH NC_011740.1 2717029 2718195 D this protein has no known enzymatic function; beta-lactam binding protein AmpH 2717029..2718195 Escherichia fergusonii ATCC 35469 7121750 YP_002383754.1 CDS yaiV NC_011740.1 2718196 2718864 R Evidence 4 : Homologs of previously reported genes of unknown function; DNA-binding transcriptional regulator complement(2718196..2718864) Escherichia fergusonii ATCC 35469 7120515 YP_002383755.1 CDS EFER_2649 NC_011740.1 2718907 2721915 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; flagellin structural protein complement(2718907..2721915) Escherichia fergusonii ATCC 35469 7121056 YP_002383756.1 CDS hemB NC_011740.1 2722423 2723397 D catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 2722423..2723397 Escherichia fergusonii ATCC 35469 7121197 YP_002383757.1 CDS tauD NC_011740.1 2723437 2724288 R catalyzes the conversion of taurine (2-aminoethanesulfonate) to sulfite and aminoacetaldehyde concurrently with the conversion of alpha-ketoglutarate to succinate and carbon dioxide; non-heme iron oxidase; allows the use of taurine as an alternative sulfur source; forms homodimers; taurine dioxygenase complement(2723437..2724288) Escherichia fergusonii ATCC 35469 7120637 YP_002383758.1 CDS tauC NC_011740.1 2724285 2725112 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9401024, 96404792; Product type t : transporter; taurine transporter subunit complement(2724285..2725112) Escherichia fergusonii ATCC 35469 7121981 YP_002383759.1 CDS tauB NC_011740.1 2725109 2725888 R Part of the ABC transporter complex tauABC involved in taurine import; taurine transporter ATP-binding subunit complement(2725109..2725888) Escherichia fergusonii ATCC 35469 7121980 YP_002383760.1 CDS tauA NC_011740.1 2725888 2726850 R with TauB and TauC is responsible for taurine uptake.; taurine transporter substrate binding subunit complement(2725888..2726850) Escherichia fergusonii ATCC 35469 7121979 YP_002383761.1 CDS yaiS NC_011740.1 2727499 2728182 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2727499..2728182 Escherichia fergusonii ATCC 35469 7121978 YP_002383762.1 CDS lacZ NC_011740.1 2728442 2731675 D forms a homotetramer; hydrolyzes lactose disaccharide to galactose and glucose; converts lactose to allolactose which is the natural inducer of the lac operon; beta-D-galactosidase 2728442..2731675 Escherichia fergusonii ATCC 35469 7121055 YP_002383763.1 CDS prpE NC_011740.1 2731713 2733599 R catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; propionyl-CoA synthetase complement(2731713..2733599) Escherichia fergusonii ATCC 35469 7123303 YP_002383764.1 CDS prpD NC_011740.1 2733639 2735090 R functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C; 2-methylcitrate dehydratase complement(2733639..2735090) Escherichia fergusonii ATCC 35469 7120141 YP_002383765.1 CDS prpC NC_011740.1 2735124 2736293 R catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity; methylcitrate synthase complement(2735124..2736293) Escherichia fergusonii ATCC 35469 7120140 YP_002383766.1 CDS prpB NC_011740.1 2736338 2737228 R catalyzes the formation of pyruvate and succinate from 2-methylisocitrate; 2-methylisocitrate lyase complement(2736338..2737228) Escherichia fergusonii ATCC 35469 7120139 YP_002383767.1 CDS prpR NC_011740.1 2737467 2739053 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9325432, 15805526; Product type r : regulator; DNA-binding transcriptional activator 2737467..2739053 Escherichia fergusonii ATCC 35469 7123650 YP_002383768.1 CDS yahO NC_011740.1 2739151 2739426 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2739151..2739426) Escherichia fergusonii ATCC 35469 7120142 YP_002383769.1 CDS yahN NC_011740.1 2739612 2740244 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12879215; Product type t : transporter; neutral amino-acid efflux system 2739612..2740244 Escherichia fergusonii ATCC 35469 7123798 YP_002383770.1 CDS EFER_2664 NC_011740.1 2740351 2741769 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 2740351..2741769 Escherichia fergusonii ATCC 35469 7121050 YP_002383771.1 CDS EFER_2665 NC_011740.1 2741864 2742535 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; gntR family regulatory protein 2741864..2742535 Escherichia fergusonii ATCC 35469 7123304 YP_002383772.1 CDS EFER_2666 NC_011740.1 2742594 2743619 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; L-threonine 3-dehydrogenase complement(2742594..2743619) Escherichia fergusonii ATCC 35469 7121320 YP_002383773.1 CDS EFER_2667 NC_011740.1 2743591 2744880 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; Hexuronate transporter complement(2743591..2744880) Escherichia fergusonii ATCC 35469 7121321 YP_002383774.1 CDS EFER_2668 NC_011740.1 2745180 2746721 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2745180..2746721) Escherichia fergusonii ATCC 35469 7123305 YP_002383775.1 CDS EFER_2669 NC_011740.1 2747082 2747519 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2747082..2747519) Escherichia fergusonii ATCC 35469 7121322 YP_002383776.1 CDS yahA NC_011740.1 2747733 2748839 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15995192; Product type e : enzyme; cyclic di-GMP phosphodiesterase complement(2747733..2748839) Escherichia fergusonii ATCC 35469 7121323 YP_002383777.1 CDS yedL NC_011740.1 2749968 2750447 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; acyltransferase 2749968..2750447 Escherichia fergusonii ATCC 35469 7121041 YP_002383778.1 CDS EFER_2672 NC_011740.1 2750728 2751579 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 17575004; Product type pe : enzyme; aldo-keto reductase 2750728..2751579 Escherichia fergusonii ATCC 35469 7121541 YP_002383779.1 CDS EFER_2673 NC_011740.1 2751606 2752595 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; aldo-keto reductase 2751606..2752595 Escherichia fergusonii ATCC 35469 7121324 YP_002383780.1 CDS EFER_2674 NC_011740.1 2752630 2753523 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; LysR family transcriptional regulator complement(2752630..2753523) Escherichia fergusonii ATCC 35469 7121325 YP_002383781.1 CDS EFER_2675 NC_011740.1 2754232 2754492 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 2754232..2754492 Escherichia fergusonii ATCC 35469 7123846 YP_002383782.1 CDS tfaQ NC_011740.1 2755065 2755649 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; tail fiber chaperone; Qin prophage complement(2755065..2755649) Escherichia fergusonii ATCC 35469 7121326 YP_002383783.1 CDS EFER_2677 NC_011740.1 2755649 2757430 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; tail fiber protein (fragment) complement(2755649..2757430) Escherichia fergusonii ATCC 35469 7121987 YP_002383784.1 CDS I NC_011740.1 2757330 2757893 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; tail protein I complement(2757330..2757893) Escherichia fergusonii ATCC 35469 7121327 YP_002383785.1 CDS GpJ NC_011740.1 2757883 2758803 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Baseplate assembly protein J (GpJ) complement(2757883..2758803) Escherichia fergusonii ATCC 35469 7120716 YP_002383786.1 CDS W NC_011740.1 2758787 2759140 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; baseplate assembly protein W complement(2758787..2759140) Escherichia fergusonii ATCC 35469 7120609 YP_002383787.1 CDS EFER_2681 NC_011740.1 2759181 2760332 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; Phage late control gene D protein complement(2759181..2760332) Escherichia fergusonii ATCC 35469 7124080 YP_002383788.1 CDS X NC_011740.1 2760301 2760516 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; tail protein X complement(2760301..2760516) Escherichia fergusonii ATCC 35469 7121328 YP_002383789.1 CDS EFER_2683 NC_011740.1 2760491 2760961 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; Phage-related tail protein complement(2760491..2760961) Escherichia fergusonii ATCC 35469 7122380 YP_002383790.1 CDS EFER_2684 NC_011740.1 2760958 2762868 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; hypothetical protein complement(2760958..2762868) Escherichia fergusonii ATCC 35469 7121329 YP_002383791.1 CDS EFER_2685 NC_011740.1 2762971 2763282 R Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein complement(2762971..2763282) Escherichia fergusonii ATCC 35469 7121330 YP_002383792.1 CDS EFER_2686 NC_011740.1 2763329 2763835 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; major tail tube protein complement(2763329..2763835) Escherichia fergusonii ATCC 35469 7121331 YP_002383793.1 CDS EFER_2687 NC_011740.1 2763832 2765376 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; major tail sheath protein complement(2763832..2765376) Escherichia fergusonii ATCC 35469 7123306 YP_002383794.1 CDS V NC_011740.1 2765339 2765995 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7483254; Product type h : extrachromosomal origin; Baseplate assembly protein V (GpV) complement(2765339..2765995) Escherichia fergusonii ATCC 35469 7121332 YP_002383795.1 CDS EFER_2689 NC_011740.1 2765949 2766500 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(2765949..2766500) Escherichia fergusonii ATCC 35469 7122654 YP_002383796.1 CDS EFER_2690 NC_011740.1 2766511 2767260 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(2766511..2767260) Escherichia fergusonii ATCC 35469 7121333 YP_002383797.1 CDS EFER_2691 NC_011740.1 2767169 2767579 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(2767169..2767579) Escherichia fergusonii ATCC 35469 7121334 YP_002383798.1 CDS EFER_2692 NC_011740.1 2767525 2767854 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(2767525..2767854) Escherichia fergusonii ATCC 35469 7121335 YP_002383799.1 CDS EFER_2693 NC_011740.1 2767926 2770199 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; ATP-dependent Clp protease proteolytic subunit (Endopeptidase Clp) of prophage complement(2767926..2770199) Escherichia fergusonii ATCC 35469 7123847 YP_002383800.1 CDS EFER_2694 NC_011740.1 2769961 2771472 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; head-tail preconnector protein from phage origin complement(2769961..2771472) Escherichia fergusonii ATCC 35469 7121336 YP_002383801.1 CDS EFER_2695 NC_011740.1 2771481 2771696 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(2771481..2771696) Escherichia fergusonii ATCC 35469 7121337 YP_002383802.1 CDS EFER_2696 NC_011740.1 2771693 2773810 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; DNA packaging protein of prophage ( terminase large subunit) complement(2771693..2773810) Escherichia fergusonii ATCC 35469 7121338 YP_002383803.1 CDS EFER_2697 NC_011740.1 2773814 2774332 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(2773814..2774332) Escherichia fergusonii ATCC 35469 7121339 YP_002383804.1 CDS EFER_2698 NC_011740.1 2774460 2774696 R Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein complement(2774460..2774696) Escherichia fergusonii ATCC 35469 7123848 YP_002383805.1 CDS borD NC_011740.1 2774865 2775206 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 95173101; Product type pm : membrane component; lipoprotein; DLP12 prophage 2774865..2775206 Escherichia fergusonii ATCC 35469 7121340 YP_002383806.1 CDS rzpD NC_011740.1 2775238 2775711 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2019562; Product type pe : enzyme; murein endopeptidase; DLP12 prophage complement(2775238..2775711) Escherichia fergusonii ATCC 35469 7123906 YP_002383807.1 CDS ybcS NC_011740.1 2775696 2776193 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3017988; Product type pe : enzyme; lysozyme; DLP12 prophage complement(2775696..2776193) Escherichia fergusonii ATCC 35469 7121188 YP_002383808.1 CDS essD NC_011740.1 2776193 2776408 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2019562; Product type pe : enzyme; phage lysis protein S; DLP12 prophage complement(2776193..2776408) Escherichia fergusonii ATCC 35469 7121089 YP_002383809.1 CDS EFER_2703 NC_011740.1 2776597 2777337 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; araC-type regulatory protein from bacteriophage origin complement(2776597..2777337) Escherichia fergusonii ATCC 35469 7119964 YP_002383810.1 CDS EFER_2704 NC_011740.1 2777678 2778637 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(2777678..2778637) Escherichia fergusonii ATCC 35469 7121341 YP_002383811.1 CDS blc NC_011740.1 2778830 2779354 D lipocalin; globomycin-sensitive outer membrane lipoprotein; outer membrane lipoprotein Blc 2778830..2779354 Escherichia fergusonii ATCC 35469 7121342 YP_002383812.1 CDS ybcQ NC_011740.1 2779509 2779901 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8648624, 9278503; Product type pf : factor; antitermination protein Q-like protein; DLP12 prophage complement(2779509..2779901) Escherichia fergusonii ATCC 35469 7121674 YP_002383813.1 CDS rusA NC_011740.1 2780109 2780471 R DLP12 prophage; Holliday junction resolvase; endodeoxyribonuclease RUS complement(2780109..2780471) Escherichia fergusonii ATCC 35469 7121088 YP_002383814.1 CDS ybcO NC_011740.1 2780468 2780758 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(2780468..2780758) Escherichia fergusonii ATCC 35469 7121166 YP_002383815.1 CDS EFER_2709 NC_011740.1 2780751 2781002 R DLP12 prophage; conserved protein similar to phage 82 and lambda proteins; prophage protein NinE complement(2780751..2781002) Escherichia fergusonii ATCC 35469 7121087 YP_002383816.1 CDS ybcN NC_011740.1 2780921 2781376 R DLP12 prophage; hypothetical protein complement(2780921..2781376) Escherichia fergusonii ATCC 35469 7121343 YP_002383817.1 CDS EFER_2711 NC_011740.1 2781564 2782073 R Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein complement(2781564..2782073) Escherichia fergusonii ATCC 35469 7121086 YP_002383818.1 CDS EFER_2712 NC_011740.1 2782123 2782344 R Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein complement(2782123..2782344) Escherichia fergusonii ATCC 35469 7121344 YP_002383819.1 CDS EFER_2713 NC_011740.1 2782465 2783175 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2782465..2783175) Escherichia fergusonii ATCC 35469 7121345 YP_002383820.1 CDS EFER_2714 NC_011740.1 2783172 2783585 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(2783172..2783585) Escherichia fergusonii ATCC 35469 7123849 YP_002383821.1 CDS EFER_2715 NC_011740.1 2783582 2783812 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2783582..2783812) Escherichia fergusonii ATCC 35469 7121346 YP_002383822.1 CDS EFER_2716 NC_011740.1 2783809 2784066 R Evidence 5 : No homology to any previously reported sequences; Product type h : extrachromosomal origin; hypothetical protein complement(2783809..2784066) Escherichia fergusonii ATCC 35469 7121347 YP_002383823.1 CDS EFER_2717 NC_011740.1 2784006 2784299 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Ren protein from phage origin complement(2784006..2784299) Escherichia fergusonii ATCC 35469 7123850 YP_002383824.1 CDS EFER_2718 NC_011740.1 2784296 2784997 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; replication protein P of bacteriophage complement(2784296..2784997) Escherichia fergusonii ATCC 35469 7121348 YP_002383825.1 CDS EFER_2719 NC_011740.1 2784994 2786013 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2995831; Product type h : extrachromosomal origin; Replication protein O frm phage origin complement(2784994..2786013) Escherichia fergusonii ATCC 35469 7123851 YP_002383826.1 CDS EFER_2720 NC_011740.1 2786010 2786501 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 612476; Product type h : extrachromosomal origin; Regulatory protein CII from bacteriophage origin; coiled-coil complement(2786010..2786501) Escherichia fergusonii ATCC 35469 7121349 YP_002383827.1 CDS cro NC_011740.1 2786580 2786813 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; represror Cro complement(2786580..2786813) Escherichia fergusonii ATCC 35469 7121350 YP_002383828.1 CDS EFER_2722 NC_011740.1 2786882 2787610 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Regulatory protein CI from bacteriophage origin 2786882..2787610 Escherichia fergusonii ATCC 35469 7122807 YP_002383829.1 CDS EFER_2723 NC_011740.1 2787740 2788879 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; peptidase m, neutral zinc metallopeptidases, zinc-binding site; protein 2787740..2788879 Escherichia fergusonii ATCC 35469 7121351 YP_002383830.1 CDS EFER_2724 NC_011740.1 2788876 2789388 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2788876..2789388 Escherichia fergusonii ATCC 35469 7121352 YP_002383831.1 CDS EFER_2725 NC_011740.1 2789663 2790073 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; prophage Kil protein 2789663..2790073 Escherichia fergusonii ATCC 35469 7123307 YP_002383832.1 CDS EFER_2726 NC_011740.1 2790149 2790445 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; host-nuclease inhibitor protein Gam of bacteriophage 2790149..2790445 Escherichia fergusonii ATCC 35469 7121353 YP_002383833.1 CDS EFER_2727 NC_011740.1 2790451 2791236 D Evidence 2b : Function of strongly homologous gene; PubMedId : 6458018, 6221115; Product type h : extrachromosomal origin; Recombination protein bet from phage origin 2790451..2791236 Escherichia fergusonii ATCC 35469 7123852 YP_002383834.1 CDS EFER_2728 NC_011740.1 2791233 2791913 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; exonuclease from phage origin 2791233..2791913 Escherichia fergusonii ATCC 35469 7121354 YP_002383835.1 CDS EFER_2729 NC_011740.1 2792064 2792621 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; DNA N-6-adenine-methyltransferase from phage origin 2792064..2792621 Escherichia fergusonii ATCC 35469 7121355 YP_002383836.1 CDS EFER_2730 NC_011740.1 2792599 2792913 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2792599..2792913 Escherichia fergusonii ATCC 35469 7123853 YP_002383837.1 CDS EFER_2731 NC_011740.1 2793012 2793230 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2793012..2793230 Escherichia fergusonii ATCC 35469 7121356 YP_002383838.1 CDS EFER_2732 NC_011740.1 2793278 2793556 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 2793278..2793556 Escherichia fergusonii ATCC 35469 7123854 YP_002383839.1 CDS xis NC_011740.1 2793553 2793972 D Evidence 2b : Function of strongly homologous gene; PubMedId : 11401961, 12379716; Product type h : extrachromosomal origin; Excisionase from phage origin 2793553..2793972 Escherichia fergusonii ATCC 35469 7121357 YP_002383840.1 CDS int NC_011740.1 2793849 2795009 D Evidence 2b : Function of strongly homologous gene; PubMedId : 3491212, 12562822; Product type h : extrachromosomal origin; Integrase from phage origin 2793849..2795009 Escherichia fergusonii ATCC 35469 7123472 YP_002383841.1 CDS proA NC_011740.1 2795214 2796467 R Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase complement(2795214..2796467) Escherichia fergusonii ATCC 35469 7120070 YP_002383842.1 CDS proB NC_011740.1 2796479 2797582 R catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase complement(2796479..2797582) Escherichia fergusonii ATCC 35469 7120132 YP_002383843.1 CDS phoE NC_011740.1 2797870 2798925 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89178658, 89380253, 92219258, 98090453, 1380671, 1848301, 1848682, 6089111, 6341601, 7679770; Product type t : transporter; outer membrane phosphoporin protein E 2797870..2798925 Escherichia fergusonii ATCC 35469 7120133 YP_002383844.1 CDS crl NC_011740.1 2798964 2799365 R involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS; DNA-binding transcriptional regulator Crl complement(2798964..2799365) Escherichia fergusonii ATCC 35469 7122599 YP_002383845.1 CDS frsA NC_011740.1 2799423 2800667 R forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation; fermentation/respiration switch protein complement(2799423..2800667) Escherichia fergusonii ATCC 35469 7122806 YP_002383846.1 CDS gpt NC_011740.1 2800760 2801218 R catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase complement(2800760..2801218) Escherichia fergusonii ATCC 35469 7123014 YP_002383847.1 CDS pepD NC_011740.1 2801479 2802936 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1695895, 21101837, 88121730, 92204123, 2651887; Product type e : enzyme; aminoacyl-histidine dipeptidase ABC transporter periplasmic-binding protein 2801479..2802936 Escherichia fergusonii ATCC 35469 7120613 YP_002383848.1 CDS EFER_2742 NC_011740.1 2802963 2803226 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2802963..2803226 Escherichia fergusonii ATCC 35469 7122576 YP_002383849.1 CDS EFER_2743 NC_011740.1 2803235 2803813 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2803235..2803813) Escherichia fergusonii ATCC 35469 7121358 YP_002383850.1 CDS prfH NC_011740.1 2803821 2804321 R similar to release factor 1 and 2; peptide chain release factor-like protein complement(2803821..2804321) Escherichia fergusonii ATCC 35469 7121359 YP_002383851.1 CDS EFER_2745 NC_011740.1 2804432 2805571 R mutations in this gene result in a compromised ability for drug-inducible mexXY expression; expression is inducible by the same ribosome-targeting agents that induce mexXY; hypothetical protein complement(2804432..2805571) Escherichia fergusonii ATCC 35469 7123647 YP_002383852.1 CDS yafP NC_011740.1 2805889 2806341 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12813093; Product type pe : enzyme; hypothetical protein complement(2805889..2806341) Escherichia fergusonii ATCC 35469 7121360 YP_002383853.1 CDS yafO NC_011740.1 2806351 2806749 R YafO overproduction induces toxicity; it is believed to be the toxin of a toxin-antitoxin pair; unknown function; toxin YafO complement(2806351..2806749) Escherichia fergusonii ATCC 35469 7124035 YP_002383854.1 CDS yafN NC_011740.1 2806752 2807045 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12813093, 14594833; Product type pf : factor; antitoxin of the YafO-YafN toxin-antitoxin system complement(2806752..2807045) Escherichia fergusonii ATCC 35469 7122422 YP_002383855.1 CDS dinB NC_011740.1 2807097 2808152 R involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV complement(2807097..2808152) Escherichia fergusonii ATCC 35469 7122421 YP_002383856.1 CDS mbhA NC_011740.1 2808223 2809113 R Evidence 2b : Function of strongly homologous gene; PubMedId : 15687208; Product type s : structure; hypothetical protein complement(2808223..2809113) Escherichia fergusonii ATCC 35469 7122897 YP_002383857.1 CDS fhiA NC_011740.1 2808563 2810692 D Evidence 2b : Function of strongly homologous gene; PubMedId : 7783646, 15687208; Product type s : structure; flagellar system protein 2808563..2810692 Escherichia fergusonii ATCC 35469 7121236 YP_002383858.1 CDS recD NC_011740.1 2810777 2812597 R helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit alpha complement(2810777..2812597) Escherichia fergusonii ATCC 35469 7123089 YP_002383859.1 CDS recB NC_011740.1 2812594 2816154 R helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity; exonuclease V subunit beta complement(2812594..2816154) Escherichia fergusonii ATCC 35469 7122361 YP_002383860.1 CDS ptr NC_011740.1 2816138 2819026 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91193232, 1570301, 3308636, 3534791, 3537960, 8099278; Product type e : enzyme; protease III complement(2816138..2819026) Escherichia fergusonii ATCC 35469 7122359 YP_002383861.1 CDS recC NC_011740.1 2819203 2822571 R catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination; exonuclease V subunit gamma complement(2819203..2822571) Escherichia fergusonii ATCC 35469 7123461 YP_002383862.1 CDS EFER_2756 NC_011740.1 2822587 2822907 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2822587..2822907) Escherichia fergusonii ATCC 35469 7122360 YP_002383863.1 CDS EFER_2757 NC_011740.1 2822892 2823296 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2822892..2823296) Escherichia fergusonii ATCC 35469 7123308 YP_002383864.1 CDS ppdB NC_011740.1 2823293 2824096 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type f : factor; prepilin peptidase-dependent protein B complement(2823293..2824096) Escherichia fergusonii ATCC 35469 7121361 YP_002383865.1 CDS ppdA NC_011740.1 2823847 2824317 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; hypothetical protein complement(2823847..2824317) Escherichia fergusonii ATCC 35469 7123645 YP_002383866.1 CDS thyA NC_011740.1 2824492 2825286 R ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase complement(2824492..2825286) Escherichia fergusonii ATCC 35469 7120108 YP_002383867.1 CDS lgt NC_011740.1 2825293 2826168 R transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase complement(2825293..2826168) Escherichia fergusonii ATCC 35469 7123984 YP_002383868.1 CDS ptsP NC_011740.1 2826332 2828578 R member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr; bifunctional phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain-containing protein complement(2826332..2828578) Escherichia fergusonii ATCC 35469 7120830 YP_002383869.1 CDS nudH NC_011740.1 2828591 2829121 R hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase complement(2828591..2829121) Escherichia fergusonii ATCC 35469 7122317 YP_002383870.1 CDS mutH NC_011740.1 2829795 2830499 D MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair; DNA mismatch repair protein 2829795..2830499 Escherichia fergusonii ATCC 35469 7119673 YP_002383871.1 CDS ygdQ NC_011740.1 2830563 2831276 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2830563..2831276 Escherichia fergusonii ATCC 35469 7120652 YP_002383872.1 CDS ygdR NC_011740.1 2831409 2831627 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2831409..2831627 Escherichia fergusonii ATCC 35469 7123878 YP_002383873.1 CDS tas NC_011740.1 2831735 2832775 D complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH; aldo-keto reductase 2831735..2832775 Escherichia fergusonii ATCC 35469 7121504 YP_002383874.1 CDS EFER_2768 NC_011740.1 2832918 2834588 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2832918..2834588 Escherichia fergusonii ATCC 35469 7123406 YP_002383875.1 CDS ygeD NC_011740.1 2834627 2835820 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8300626; Product type pm : membrane component; lysophospholipid transporter LplT complement(2834627..2835820) Escherichia fergusonii ATCC 35469 7121362 YP_002383876.1 CDS aas NC_011740.1 2835813 2837972 R Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1; bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase complement(2835813..2837972) Escherichia fergusonii ATCC 35469 7121505 YP_002383877.1 CDS EFER_2771 NC_011740.1 2838255 2838554 R Evidence 6 : Doubtful CDS; hypothetical protein complement(2838255..2838554) Escherichia fergusonii ATCC 35469 7119696 YP_002383878.1 CDS galR NC_011740.1 2838567 2839595 D controls transcription of galETKM; DNA-binding transcriptional regulator GalR 2838567..2839595 Escherichia fergusonii ATCC 35469 7119697 YP_002383879.1 CDS lysA NC_011740.1 2839610 2840872 R catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding; diaminopimelate decarboxylase complement(2839610..2840872) Escherichia fergusonii ATCC 35469 7120169 YP_002383880.1 CDS lysR NC_011740.1 2840982 2841917 D activates the transcription of the lysA gene encoding diaminopimelate decarboxylase; DNA-binding transcriptional regulator LysR 2840982..2841917 Escherichia fergusonii ATCC 35469 7121214 YP_002383881.1 CDS yqeF NC_011740.1 2841922 2843103 R Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase complement(2841922..2843103) Escherichia fergusonii ATCC 35469 7121217 YP_002383882.1 CDS yqeG NC_011740.1 2843347 2844576 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter 2843347..2844576 Escherichia fergusonii ATCC 35469 7119722 YP_002383883.1 CDS yqeH NC_011740.1 2845019 2845747 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; hypothetical protein 2845019..2845747 Escherichia fergusonii ATCC 35469 7119723 YP_002383884.1 CDS EFER_2778 NC_011740.1 2845989 2846912 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; regulatory protein 2845989..2846912 Escherichia fergusonii ATCC 35469 7123583 YP_002383885.1 CDS EFER_2779 NC_011740.1 2846905 2847387 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2846905..2847387 Escherichia fergusonii ATCC 35469 7121364 YP_002383886.1 CDS nfrB NC_011740.1 2847666 2849918 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89359086, 94042873, 94042874; Product type m : membrane component; bacteriophage N4 adsorption protein B 2847666..2849918 Escherichia fergusonii ATCC 35469 7123309 YP_002383887.1 CDS nfrA NC_011740.1 2849887 2852877 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8226649; bacteriophage N4 receptor, outer membrane subunit 2849887..2852877 Escherichia fergusonii ATCC 35469 7120688 YP_002383888.1 CDS ybcH NC_011740.1 2852877 2853770 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2852877..2853770 Escherichia fergusonii ATCC 35469 7120687 YP_002383889.1 CDS codB NC_011740.1 2854043 2855302 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92349961; Product type t : transporter; cytosine permease 2854043..2855302 Escherichia fergusonii ATCC 35469 7121083 YP_002383890.1 CDS codA NC_011740.1 2855292 2856575 D Catalyzes the deamination of cytosine to uracil and ammonia; cytosine deaminase 2855292..2856575 Escherichia fergusonii ATCC 35469 7123994 YP_002383891.1 CDS EFER_2786 NC_011740.1 2856796 2858532 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2856796..2858532) Escherichia fergusonii ATCC 35469 7120912 YP_002383892.1 CDS EFER_2787 NC_011740.1 2858775 2859131 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2858775..2859131 Escherichia fergusonii ATCC 35469 7121365 YP_002383893.1 CDS EFER_2788 NC_011740.1 2858916 2859818 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2858916..2859818) Escherichia fergusonii ATCC 35469 7121366 YP_002383894.1 CDS EFER_2789 NC_011740.1 2859933 2860121 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; protein perC (protein bfpW) (fragment) complement(2859933..2860121) Escherichia fergusonii ATCC 35469 7121367 YP_002383895.1 CDS EFER_2790 NC_011740.1 2860236 2860460 R hypothetical protein complement(2860236..2860460) Escherichia fergusonii ATCC 35469 7121368 YP_002383896.1 CDS insE NC_011740.1 2860535 2860843 D Evidence 1b : Function experimentally demonstrated in the studied species; Product type h : extrachromosomal origin; IS3 element protein InsE 2860535..2860843 Escherichia fergusonii ATCC 35469 7123855 YP_002383897.1 CDS insF NC_011740.1 2860840 2861706 D Evidence 1b : Function experimentally demonstrated in the studied species; Product type h : extrachromosomal origin; IS3 element protein InsF 2860840..2861706 Escherichia fergusonii ATCC 35469 7123745 YP_002383898.1 CDS EFER_2793 NC_011740.1 2861798 2862229 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2861798..2862229 Escherichia fergusonii ATCC 35469 7120743 YP_002383899.1 CDS EFER_2794 NC_011740.1 2862316 2862525 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; regulatory protein 2862316..2862525 Escherichia fergusonii ATCC 35469 7121369 YP_002383900.1 CDS EFER_2795 NC_011740.1 2862607 2863674 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2862607..2863674 Escherichia fergusonii ATCC 35469 7121370 YP_002383901.1 CDS EFER_2796 NC_011740.1 2863953 2864858 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2863953..2864858 Escherichia fergusonii ATCC 35469 7121371 YP_002383902.1 CDS EFER_2797 NC_011740.1 2864855 2865043 D hypothetical protein 2864855..2865043 Escherichia fergusonii ATCC 35469 7121372 YP_002383903.1 CDS EFER_2798 NC_011740.1 2865229 2865771 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2865229..2865771) Escherichia fergusonii ATCC 35469 7123856 YP_002383904.1 CDS EFER_2799 NC_011740.1 2865689 2866528 R Evidence 2b : Function of strongly homologous gene; Product type pe : enzyme; transposase ORF B, IS911 complement(2865689..2866528) Escherichia fergusonii ATCC 35469 7121373 YP_002383905.1 CDS EFER_2801 NC_011740.1 2866973 2867443 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; marR-family regulatory protein 2866973..2867443 Escherichia fergusonii ATCC 35469 7121375 YP_002383906.1 CDS EFER_2803 NC_011740.1 2867785 2868138 R regulates the expression of of the arsRBC involved in resistance to arsenic; DNA-binding transcriptional repressor ArsR complement(2867785..2868138) Escherichia fergusonii ATCC 35469 7120554 YP_002383907.1 CDS EFER_2804 NC_011740.1 2868232 2870280 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2868232..2870280 Escherichia fergusonii ATCC 35469 7123857 YP_002383908.1 CDS EFER_2805 NC_011740.1 2870259 2872043 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; helicase 2870259..2872043 Escherichia fergusonii ATCC 35469 7121377 YP_002383909.1 CDS int NC_011740.1 2872100 2873269 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Integrase complement(2872100..2873269) Escherichia fergusonii ATCC 35469 7123858 YP_002383910.1 CDS ygeR NC_011740.1 2873586 2874344 R Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 15150243; Product type r : regulator; Tetratricopeptide repeat transcriptional regulator complement(2873586..2874344) Escherichia fergusonii ATCC 35469 7120069 YP_002383911.1 CDS EFER_2808 NC_011740.1 2874428 2875159 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein complement(2874428..2875159) Escherichia fergusonii ATCC 35469 7123330 YP_002383912.1 CDS EFER_2809 NC_011740.1 2875164 2875994 R extracellular solute-binding protein complement(2875164..2875994) Escherichia fergusonii ATCC 35469 7121378 YP_002383913.1 CDS EFER_2810 NC_011740.1 2876018 2876890 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; dioxygenase complement(2876018..2876890) Escherichia fergusonii ATCC 35469 7121379 YP_002383914.1 CDS EFER_2811 NC_011740.1 2876914 2878434 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; amino acid ABC transporter permease complement(2876914..2878434) Escherichia fergusonii ATCC 35469 7121380 YP_002383915.1 CDS EFER_2812 NC_011740.1 2878811 2879731 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; regulatory protein, LysR:LysR substrate-binding domain (fragment) 2878811..2879731 Escherichia fergusonii ATCC 35469 7121157 YP_002383916.1 CDS EFER_2813 NC_011740.1 2879786 2881114 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; pyridine nucleotide-disulfide oxidoreductase 2879786..2881114 Escherichia fergusonii ATCC 35469 7123694 YP_002383917.1 CDS EFER_2814 NC_011740.1 2881129 2881563 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type e : enzyme; endoribonuclease 2881129..2881563 Escherichia fergusonii ATCC 35469 7123150 YP_002383918.1 CDS EFER_2815 NC_011740.1 2881560 2882234 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2881560..2882234 Escherichia fergusonii ATCC 35469 7123151 YP_002383919.1 CDS EFER_2816 NC_011740.1 2882065 2883402 D catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine; acetylornithine deacetylase 2882065..2883402 Escherichia fergusonii ATCC 35469 7120390 YP_002383920.1 CDS gadA NC_011740.1 2883597 2884997 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92155241, 92394884, 99406302, 1522060, 1740158, 7764225, 9298646; Product type e : enzyme; glutamate decarboxylase 2883597..2884997 Escherichia fergusonii ATCC 35469 7120391 YP_002383921.1 CDS ybaS NC_011740.1 2885195 2886142 D catalyzes the formation of glutamate from glutamine; glutaminase 2885195..2886142 Escherichia fergusonii ATCC 35469 7120161 YP_002383922.1 CDS yagT NC_011740.1 2886267 2886881 D Evidence 2b : Function of strongly homologous gene; Product type pe : enzyme; xanthine dehydrogenase, iron-sulfur binding subunit 2886267..2886881 Escherichia fergusonii ATCC 35469 7121070 YP_002383923.1 CDS yagS NC_011740.1 2886878 2887834 D Evidence 2b : Function of strongly homologous gene; Product type pe : enzyme; xanthine dehydrogenase yagS, FAD binding subunit 2886878..2887834 Escherichia fergusonii ATCC 35469 7121040 YP_002383924.1 CDS yagR NC_011740.1 2887831 2890029 D Evidence 2b : Function of strongly homologous gene; Product type pe : enzyme; xanthine dehydrogenase, molybdenum binding subunit 2887831..2890029 Escherichia fergusonii ATCC 35469 7121039 YP_002383925.1 CDS yagQ NC_011740.1 2890039 2890974 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2890039..2890974 Escherichia fergusonii ATCC 35469 7122180 YP_002383926.1 CDS EFER_2823 NC_011740.1 2890971 2891534 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; MobA-like protein 2890971..2891534 Escherichia fergusonii ATCC 35469 7122425 YP_002383927.1 CDS idi NC_011740.1 2891589 2892170 D catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate; isopentenyl-diphosphate delta-isomerase 2891589..2892170 Escherichia fergusonii ATCC 35469 7120392 YP_002383928.1 CDS lysS NC_011740.1 2892213 2893730 R class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase complement(2892213..2893730) Escherichia fergusonii ATCC 35469 7120723 YP_002383929.1 CDS prfB NC_011740.1 2893740 2894838 R recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 complement(join(2893740..2894762,2894764..2894838)) Escherichia fergusonii ATCC 35469 7123285 YP_002383930.1 CDS recJ NC_011740.1 2894929 2896662 R 5'-3' single-stranded-DNA-specific exonuclease; ssDNA exonuclease RecJ complement(2894929..2896662) Escherichia fergusonii ATCC 35469 7120124 YP_002383931.1 CDS dsbC NC_011740.1 2896668 2897378 R DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity; thiol:disulfide interchange protein DsbC complement(2896668..2897378) Escherichia fergusonii ATCC 35469 7121381 YP_002383932.1 CDS xerD NC_011740.1 2897403 2898299 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD complement(2897403..2898299) Escherichia fergusonii ATCC 35469 7122922 YP_002383933.1 CDS fldB NC_011740.1 2898411 2898932 D An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic; flavodoxin FldB 2898411..2898932 Escherichia fergusonii ATCC 35469 7124029 YP_002383934.1 CDS ygfX NC_011740.1 2898972 2899379 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2898972..2899379) Escherichia fergusonii ATCC 35469 7123562 YP_002383935.1 CDS ygfY NC_011740.1 2899360 2899626 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2899360..2899626) Escherichia fergusonii ATCC 35469 7119840 YP_002383936.1 CDS EFER_2833 NC_011740.1 2899616 2899774 R Evidence 6 : Doubtful CDS; hypothetical protein complement(2899616..2899774) Escherichia fergusonii ATCC 35469 7119841 YP_002383937.1 CDS ygfZ NC_011740.1 2899878 2900858 D physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator; global regulator 2899878..2900858 Escherichia fergusonii ATCC 35469 7120393 YP_002383938.1 CDS yqfA NC_011740.1 2900935 2901594 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hemolysin, inner membrane subunit complement(2900935..2901594) Escherichia fergusonii ATCC 35469 7123059 YP_002383939.1 CDS yqfB NC_011740.1 2901758 2902069 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2901758..2902069) Escherichia fergusonii ATCC 35469 7119724 YP_002383940.1 CDS bglA NC_011740.1 2902108 2903547 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87222180, 88297127, 92334140; Product type e : enzyme; 6-phospho-beta-glucosidase 2902108..2903547 Escherichia fergusonii ATCC 35469 7123036 YP_002383941.1 CDS EFER_2838 NC_011740.1 2903595 2904533 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; outer membrane protein complement(2903595..2904533) Escherichia fergusonii ATCC 35469 7121660 YP_002383942.1 CDS gcvP NC_011740.1 2904944 2907817 R acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase complement(2904944..2907817) Escherichia fergusonii ATCC 35469 7123152 YP_002383943.1 CDS gcvH NC_011740.1 2907936 2908325 R part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H complement(2907936..2908325) Escherichia fergusonii ATCC 35469 7120180 YP_002383944.1 CDS gcvT NC_011740.1 2908348 2909442 R catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T complement(2908348..2909442) Escherichia fergusonii ATCC 35469 7123117 YP_002383945.1 CDS visC NC_011740.1 2909890 2911092 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1339425; Product type pe : enzyme; hypothetical protein complement(2909890..2911092) Escherichia fergusonii ATCC 35469 7120182 YP_002383946.1 CDS ubiH NC_011740.1 2911115 2912293 R Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; 2-octaprenyl-6-methoxyphenyl hydroxylase complement(2911115..2912293) Escherichia fergusonii ATCC 35469 7122658 YP_002383947.1 CDS pepP NC_011740.1 2912290 2913615 R exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide; proline aminopeptidase P II complement(2912290..2913615) Escherichia fergusonii ATCC 35469 7124073 YP_002383948.1 CDS ygfB NC_011740.1 2913641 2914219 R the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; hypothetical protein complement(2913641..2914219) Escherichia fergusonii ATCC 35469 7122577 YP_002383949.1 CDS zapA NC_011740.1 2914387 2914716 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 412171; Product type cp : cell process; Z-ring-associated protein 2914387..2914716 Escherichia fergusonii ATCC 35469 7119839 YP_002383950.1 CDS EFER_2848 NC_011740.1 2914666 2915043 R Evidence 6 : Doubtful CDS; hypothetical protein complement(2914666..2915043) Escherichia fergusonii ATCC 35469 7119771 YP_002383951.1 CDS ygfA NC_011740.1 2915010 2915558 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14727089, 2579060; Product type pe : enzyme; ligase 2915010..2915558 Escherichia fergusonii ATCC 35469 7121945 YP_002383952.1 CDS serA NC_011740.1 2915945 2917177 R catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase complement(2915945..2917177) Escherichia fergusonii ATCC 35469 7123822 YP_002383953.1 CDS rpiA NC_011740.1 2917420 2918079 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12517338, 4598000, 93374859, 1917830, 8366047, 9298646, 9600841, 1104357; Product type e : enzyme; ribose 5-phosphate isomerase complement(2917420..2918079) Escherichia fergusonii ATCC 35469 7121769 YP_002383954.1 CDS argP NC_011740.1 2918239 2919132 D specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport; chromosome replication initiation inhibitor protein 2918239..2919132 Escherichia fergusonii ATCC 35469 7123319 YP_002383955.1 CDS yggE NC_011740.1 2919167 2919907 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2919167..2919907) Escherichia fergusonii ATCC 35469 7120542 YP_002383956.1 CDS argO NC_011740.1 2920188 2920823 R Involved in the export of arginine; arginine exporter protein complement(2920188..2920823) Escherichia fergusonii ATCC 35469 7119843 YP_002383957.1 CDS mscS NC_011740.1 2920962 2921822 R participates in the regulation of osmotic pressure changes within the cel; mechanosensitive channel MscS complement(2920962..2921822) Escherichia fergusonii ATCC 35469 7120541 YP_002383958.1 CDS fbaA NC_011740.1 2922180 2923259 R catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase complement(2922180..2923259) Escherichia fergusonii ATCC 35469 7123784 YP_002383959.1 CDS pgk NC_011740.1 2923349 2924512 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(2923349..2924512) Escherichia fergusonii ATCC 35469 7119990 YP_002383960.1 CDS epd NC_011740.1 2924562 2925581 R NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate; erythrose 4-phosphate dehydrogenase complement(2924562..2925581) Escherichia fergusonii ATCC 35469 7122588 YP_002383961.1 CDS frcK NC_011740.1 2925866 2926579 R Evidence 4 : Homologs of previously reported genes of unknown function; fructose transport system kinase complement(2925866..2926579) Escherichia fergusonii ATCC 35469 7122955 YP_002383962.1 CDS yggD NC_011740.1 2926576 2927085 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator complement(2926576..2927085) Escherichia fergusonii ATCC 35469 7119842 YP_002383963.1 CDS yggF NC_011740.1 2927107 2928072 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; fructose-1,6-bisphosphatase II-like protein complement(2927107..2928072) Escherichia fergusonii ATCC 35469 7123600 YP_002383964.1 CDS yggP NC_011740.1 2928069 2929346 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; dehydrogenase complement(2928069..2929346) Escherichia fergusonii ATCC 35469 7119844 YP_002383965.1 CDS cmtA NC_011740.1 2929361 2930749 R Evidence 2b : Function of strongly homologous gene; PubMedId : 8353127; Product type t : transporter; PTS system mannitol-specific transporter subunit IIBC complement(2929361..2930749) Escherichia fergusonii ATCC 35469 7119849 YP_002383966.1 CDS cmtB NC_011740.1 2930777 2931220 R TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein; mannitol phosphotransferase subunit EIIA complement(2930777..2931220) Escherichia fergusonii ATCC 35469 7123773 YP_002383967.1 CDS EFER_2866 NC_011740.1 2931588 2932505 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; membrane protease 2931588..2932505 Escherichia fergusonii ATCC 35469 7123774 YP_002383968.1 CDS tktA NC_011740.1 2932551 2934542 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(2932551..2934542) Escherichia fergusonii ATCC 35469 7120395 YP_002383969.1 CDS EFER_2868 NC_011740.1 2934585 2934749 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 2934585..2934749 Escherichia fergusonii ATCC 35469 7122134 YP_002383970.1 CDS yggG NC_011740.1 2934820 2935578 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1310091; Product type pe : enzyme; peptidase 2934820..2935578 Escherichia fergusonii ATCC 35469 7120396 YP_002383971.1 CDS EFER_2870 NC_011740.1 2935664 2937226 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2935664..2937226) Escherichia fergusonii ATCC 35469 7119845 YP_002383972.1 CDS speB NC_011740.1 2937376 2938296 R catalyzes the formation of putrescine from agmatine; agmatinase complement(2937376..2938296) Escherichia fergusonii ATCC 35469 7123695 YP_002383973.1 CDS EFER_2872 NC_011740.1 2938487 2939644 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase complement(2938487..2939644) Escherichia fergusonii ATCC 35469 7121802 YP_002383974.1 CDS EFER_2875 NC_011740.1 2940297 2940452 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2940297..2940452) Escherichia fergusonii ATCC 35469 7120740 YP_002383975.1 CDS EFER_2876 NC_011740.1 2940961 2944998 D Evidence 2b : Function of strongly homologous gene; Product type pm : membrane component; AidA-I adhesin-like protein 2940961..2944998 Escherichia fergusonii ATCC 35469 7120397 YP_002383976.1 CDS EFER_2877 NC_011740.1 2945230 2945493 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2945230..2945493 Escherichia fergusonii ATCC 35469 7120398 YP_002383977.1 CDS speA NC_011740.1 2945537 2947513 R catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis; arginine decarboxylase complement(2945537..2947513) Escherichia fergusonii ATCC 35469 7120399 YP_002383978.1 CDS EFER_2879 NC_011740.1 2947615 2947980 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2947615..2947980 Escherichia fergusonii ATCC 35469 7123927 YP_002383979.1 CDS yqgD NC_011740.1 2947997 2948266 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2947997..2948266) Escherichia fergusonii ATCC 35469 7120400 YP_002383980.1 CDS metK NC_011740.1 2948307 2949461 D catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 2948307..2949461 Escherichia fergusonii ATCC 35469 7119725 YP_002383981.1 CDS galP NC_011740.1 2949897 2951291 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9182541; Product type t : transporter; D-galactose transporter 2949897..2951291 Escherichia fergusonii ATCC 35469 7120922 YP_002383982.1 CDS sprT NC_011740.1 2951368 2951865 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 7984428, 8113204; hypothetical protein 2951368..2951865 Escherichia fergusonii ATCC 35469 7120168 YP_002383983.1 CDS endA NC_011740.1 2951960 2952667 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 72060411, 92335461, 4955462, 7867949, 8113204; Product type e : enzyme; DNA-specific endonuclease I 2951960..2952667 Escherichia fergusonii ATCC 35469 7121811 YP_002383984.1 CDS yggJ NC_011740.1 2952747 2953478 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 2952747..2953478 Escherichia fergusonii ATCC 35469 7122948 YP_002383985.1 CDS gshB NC_011740.1 2953491 2954441 D catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 2953491..2954441 Escherichia fergusonii ATCC 35469 7123601 YP_002383986.1 CDS yqgE NC_011740.1 2954550 2955113 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2954550..2955113 Escherichia fergusonii ATCC 35469 7123189 YP_002383987.1 CDS yqgF NC_011740.1 2955113 2955529 D similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 2955113..2955529 Escherichia fergusonii ATCC 35469 7123585 YP_002383988.1 CDS yggR NC_011740.1 2955536 2956516 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1676385; Product type t : transporter; transporter complement(2955536..2956516) Escherichia fergusonii ATCC 35469 7119726 YP_002383989.1 CDS yggS NC_011740.1 2956534 2957238 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 2956534..2957238 Escherichia fergusonii ATCC 35469 7119850 YP_002383990.1 CDS yggT NC_011740.1 2957256 2957822 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2957256..2957822 Escherichia fergusonii ATCC 35469 7123602 YP_002383991.1 CDS yggU NC_011740.1 2957819 2958109 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12975589; hypothetical protein 2957819..2958109 Escherichia fergusonii ATCC 35469 7119851 YP_002383992.1 CDS yggV NC_011740.1 2958117 2958710 D HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 2958117..2958710 Escherichia fergusonii ATCC 35469 7119852 YP_002383993.1 CDS yggW NC_011740.1 2958703 2959839 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 2958703..2959839 Escherichia fergusonii ATCC 35469 7119853 YP_002383994.1 CDS EFER_2895 NC_011740.1 2960153 2961139 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; c4-dicarboxylate transport system binding protein 2960153..2961139 Escherichia fergusonii ATCC 35469 7119854 YP_002383995.1 CDS EFER_2896 NC_011740.1 2961175 2961687 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; TRAP-type C4-dicarboxylate transport system, small permease 2961175..2961687 Escherichia fergusonii ATCC 35469 7120401 YP_002383996.1 CDS ygiK NC_011740.1 2961687 2962988 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; c4-dicarboxylate permease 2961687..2962988 Escherichia fergusonii ATCC 35469 7120402 YP_002383997.1 CDS EFER_2898 NC_011740.1 2963092 2964096 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2963092..2964096) Escherichia fergusonii ATCC 35469 7119866 YP_002383998.1 CDS ansB NC_011740.1 2964213 2965259 R catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis; L-asparaginase II complement(2964213..2965259) Escherichia fergusonii ATCC 35469 7120403 YP_002383999.1 CDS yggN NC_011740.1 2965445 2966164 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11274153; hypothetical protein complement(2965445..2966164) Escherichia fergusonii ATCC 35469 7120519 YP_002384000.1 CDS yggL NC_011740.1 2966217 2966543 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2966217..2966543) Escherichia fergusonii ATCC 35469 7119848 YP_002384001.1 CDS trmB NC_011740.1 2966543 2967262 R tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase complement(2966543..2967262) Escherichia fergusonii ATCC 35469 7119847 YP_002384002.1 CDS mutY NC_011740.1 2967423 2968475 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14730969, 20187555, 20316830, 20580749, 21438845, 90046892, 92409600, 9801309, 2001994, 2197596, 9846876; Product type e : enzyme; adenine DNA glycosylase 2967423..2968475 Escherichia fergusonii ATCC 35469 7119846 YP_002384003.1 CDS yggX NC_011740.1 2968503 2968778 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14594836, 10493123, 9298646, 9868784; Product type f : factor; hypothetical protein 2968503..2968778 Escherichia fergusonii ATCC 35469 7123198 YP_002384004.1 CDS mltC NC_011740.1 2968843 2969922 D Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase C 2968843..2969922 Escherichia fergusonii ATCC 35469 7123060 YP_002384005.1 CDS EFER_2906 NC_011740.1 2969945 2970088 R Evidence 6 : Doubtful CDS; hypothetical protein complement(2969945..2970088) Escherichia fergusonii ATCC 35469 7123779 YP_002384006.1 CDS nupG NC_011740.1 2970150 2971406 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88029453, 90323001, 3311747; Product type t : transporter; nucleoside transporter 2970150..2971406 Escherichia fergusonii ATCC 35469 7123153 YP_002384007.1 CDS speC NC_011740.1 2971457 2973598 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87222180, 87260820; Product type e : enzyme; ornithine decarboxylase complement(2971457..2973598) Escherichia fergusonii ATCC 35469 7119683 YP_002384008.1 CDS yqgA NC_011740.1 2973966 2974706 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 2973966..2974706 Escherichia fergusonii ATCC 35469 7121803 YP_002384009.1 CDS EFER_2910 NC_011740.1 2974800 2974949 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2974800..2974949 Escherichia fergusonii ATCC 35469 7123584 YP_002384010.1 CDS yghJ NC_011740.1 2975950 2980521 D Evidence 2b : Function of strongly homologous gene; PubMedId : 1644747; Product type lp : lipoprotein; inner membrane lipoprotein 2975950..2980521 Escherichia fergusonii ATCC 35469 7120044 YP_002384011.1 CDS pppA NC_011740.1 2980677 2981486 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98175453; Product type e : enzyme; bifunctional prepilin leader peptidase and methylase 2980677..2981486 Escherichia fergusonii ATCC 35469 7119859 YP_002384012.1 CDS yghG NC_011740.1 2981552 2981962 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2981552..2981962 Escherichia fergusonii ATCC 35469 7120116 YP_002384013.1 CDS yghF NC_011740.1 2981978 2982931 D part of the general (type II) secretion pathway (GSP), a signal sequence-dependent process responsible for protein export; involved in trans-location of exoproteins from the cytoplasm to the periplasm; type II secretion protein GspC 2981978..2982931 Escherichia fergusonii ATCC 35469 7119858 YP_002384014.1 CDS epsD NC_011740.1 2982961 2985021 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; general secretion pathway protein D 2982961..2985021 Escherichia fergusonii ATCC 35469 7123603 YP_002384015.1 CDS epsE NC_011740.1 2985021 2986514 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; general secretion pathway protein E 2985021..2986514 Escherichia fergusonii ATCC 35469 7122956 YP_002384016.1 CDS epsF NC_011740.1 2986514 2987737 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; General secretion pathway protein F 2986514..2987737 Escherichia fergusonii ATCC 35469 7122957 YP_002384017.1 CDS EFER_2918 NC_011740.1 2987727 2988209 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; general secretion pathway protein G 2987727..2988209 Escherichia fergusonii ATCC 35469 7122958 YP_002384018.1 CDS EFER_2919 NC_011740.1 2988213 2988776 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2988213..2988776 Escherichia fergusonii ATCC 35469 7120405 YP_002384019.1 CDS EFER_2920 NC_011740.1 2988773 2989144 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; type II secretion protein 2988773..2989144 Escherichia fergusonii ATCC 35469 7120406 YP_002384020.1 CDS EFER_2921 NC_011740.1 2989141 2989746 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 2989141..2989746 Escherichia fergusonii ATCC 35469 7120407 YP_002384021.1 CDS EFER_2922 NC_011740.1 2989743 2990720 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; type II secretion protein 2989743..2990720 Escherichia fergusonii ATCC 35469 7123154 YP_002384022.1 CDS yghE NC_011740.1 2990717 2991895 D similar to general secretory pathway protein L; GspL-like protein 2990717..2991895 Escherichia fergusonii ATCC 35469 7123155 YP_002384023.1 CDS yghD NC_011740.1 2991897 2992433 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; general secretion pathway protein YghD 2991897..2992433 Escherichia fergusonii ATCC 35469 7119857 YP_002384024.1 CDS yafT NC_011740.1 2992824 2993612 D Evidence 2b : Function of strongly homologous gene; hypothetical protein 2992824..2993612 Escherichia fergusonii ATCC 35469 7123061 YP_002384025.1 CDS EFER_2926 NC_011740.1 2994435 2994788 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(2994435..2994788) Escherichia fergusonii ATCC 35469 7122423 YP_002384026.1 CDS EFER_2927 NC_011740.1 2994993 2995280 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; global regulatory protein complement(2994993..2995280) Escherichia fergusonii ATCC 35469 7120408 YP_002384027.1 CDS EFER_2928 NC_011740.1 2995926 2996285 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2995926..2996285) Escherichia fergusonii ATCC 35469 7120409 YP_002384028.1 CDS EFER_2929 NC_011740.1 2996511 2996876 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(2996511..2996876) Escherichia fergusonii ATCC 35469 7120410 YP_002384029.1 CDS gss NC_011740.1 2997489 2999348 R catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction; bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase complement(2997489..2999348) Escherichia fergusonii ATCC 35469 7120411 YP_002384030.1 CDS envY NC_011740.1 2999699 3000526 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 6317653, 2536924; Product type r : regulator; envelope protein 2999699..3000526 Escherichia fergusonii ATCC 35469 7120621 YP_002384031.1 CDS yghU NC_011740.1 3000596 3001462 D YghU; B2989; one of eight glutathione transferase proteins from E. coli; glutathione S-transferase 3000596..3001462 Escherichia fergusonii ATCC 35469 7122953 YP_002384032.1 CDS hybG NC_011740.1 3001532 3001780 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92215587, 94292472, 8021226; Product type pf : factor; hydrogenase 2 accessory protein HypG complement(3001532..3001780) Escherichia fergusonii ATCC 35469 7119860 YP_002384033.1 CDS hybF NC_011740.1 3001793 3002134 R plays a role in hydrogenase nickel cofactor insertion; hydrogenase nickel incorporation protein HybF complement(3001793..3002134) Escherichia fergusonii ATCC 35469 7120700 YP_002384034.1 CDS hybE NC_011740.1 3002127 3002615 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94292472, 8021226; Product type f : factor; hydrogenase 2-specific chaperone complement(3002127..3002615) Escherichia fergusonii ATCC 35469 7120699 YP_002384035.1 CDS hybD NC_011740.1 3002608 3003102 R protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC); hydrogenase 2 maturation endopeptidase complement(3002608..3003102) Escherichia fergusonii ATCC 35469 7123747 YP_002384036.1 CDS hybC NC_011740.1 3003102 3004805 R involved in hydrogen uptake; hydrogenase 2 large subunit complement(3003102..3004805) Escherichia fergusonii ATCC 35469 7123448 YP_002384037.1 CDS hybB NC_011740.1 3004802 3005980 R HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits; hydrogenase 2 b cytochrome subunit complement(3004802..3005980) Escherichia fergusonii ATCC 35469 7122241 YP_002384038.1 CDS hybA NC_011740.1 3005970 3006956 R Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; hydrogenase 2 protein HybA complement(3005970..3006956) Escherichia fergusonii ATCC 35469 7122240 YP_002384039.1 CDS hybO NC_011740.1 3006959 3008077 R involved in hydrogen uptake; hydrogenase 2 small subunit complement(3006959..3008077) Escherichia fergusonii ATCC 35469 7123447 YP_002384040.1 CDS yghW NC_011740.1 3008266 3008670 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3008266..3008670) Escherichia fergusonii ATCC 35469 7120701 YP_002384041.1 CDS EFER_2942 NC_011740.1 3008667 3009593 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3008667..3009593) Escherichia fergusonii ATCC 35469 7119861 YP_002384042.1 CDS yghZ NC_011740.1 3009711 3010751 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12583903; Product type e : enzyme; aldo-keto reductase 3009711..3010751 Escherichia fergusonii ATCC 35469 7123697 YP_002384043.1 CDS yqhA NC_011740.1 3010791 3011285 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(3010791..3011285) Escherichia fergusonii ATCC 35469 7123604 YP_002384044.1 CDS yghA NC_011740.1 3011476 3012360 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; oxidoreductase 3011476..3012360 Escherichia fergusonii ATCC 35469 7119727 YP_002384045.1 CDS exbD NC_011740.1 3012399 3012824 R membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbD complement(3012399..3012824) Escherichia fergusonii ATCC 35469 7119855 YP_002384046.1 CDS exbB NC_011740.1 3012831 3013565 R membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell; biopolymer transport protein ExbB complement(3012831..3013565) Escherichia fergusonii ATCC 35469 7119974 YP_002384047.1 CDS metC NC_011740.1 3013817 3015004 D catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 3013817..3015004 Escherichia fergusonii ATCC 35469 7123082 YP_002384048.1 CDS yghB NC_011740.1 3015144 3015803 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3015144..3015803 Escherichia fergusonii ATCC 35469 7120916 YP_002384049.1 CDS yqhC NC_011740.1 3015841 3016761 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator complement(3015841..3016761) Escherichia fergusonii ATCC 35469 7119856 YP_002384050.1 CDS yqhD NC_011740.1 3016933 3018096 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15327949; Product type e : enzyme; alcohol dehydrogenase 3016933..3018096 Escherichia fergusonii ATCC 35469 7119728 YP_002384051.1 CDS dkgA NC_011740.1 3018200 3019027 D methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate; 2,5-diketo-D-gluconate reductase A 3018200..3019027 Escherichia fergusonii ATCC 35469 7119729 YP_002384052.1 CDS EFER_2953 NC_011740.1 3019211 3020665 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; sodium:sulfate symporter 3019211..3020665 Escherichia fergusonii ATCC 35469 7122904 YP_002384053.1 CDS yqhH NC_011740.1 3020782 3021042 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; outer membrane lipoprotein 3020782..3021042 Escherichia fergusonii ATCC 35469 7123698 YP_002384054.1 CDS ygiQ NC_011740.1 3021093 3023312 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3021093..3023312) Escherichia fergusonii ATCC 35469 7119730 YP_002384055.1 CDS EFER_2956 NC_011740.1 3023526 3024314 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; regulator 3023526..3024314 Escherichia fergusonii ATCC 35469 7123062 YP_002384056.1 CDS EFER_2957 NC_011740.1 3024639 3026111 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; fructuronate reductase 3024639..3026111 Escherichia fergusonii ATCC 35469 7120412 YP_002384057.1 CDS EFER_2958 NC_011740.1 3026108 3027124 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; L-threonine 3-dehydrogenase 3026108..3027124 Escherichia fergusonii ATCC 35469 7120413 YP_002384058.1 CDS EFER_2959 NC_011740.1 3027135 3028145 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; Ureidoglycolate dehydrogenase 3027135..3028145 Escherichia fergusonii ATCC 35469 7120414 YP_002384059.1 CDS EFER_2960 NC_011740.1 3028218 3029201 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; c4-dicarboxylate transport system binding protein; secreted protein 3028218..3029201 Escherichia fergusonii ATCC 35469 7120415 YP_002384060.1 CDS EFER_2961 NC_011740.1 3029243 3029725 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; TRAP-type C4-dicarboxylate transport system, small permease 3029243..3029725 Escherichia fergusonii ATCC 35469 7123699 YP_002384061.1 CDS ygiK NC_011740.1 3029694 3031040 D Evidence 2b : Function of strongly homologous gene; Product type t : transporter; c4-dicarboxylate permease 3029694..3031040 Escherichia fergusonii ATCC 35469 7120416 YP_002384062.1 CDS sufI NC_011740.1 3031254 3032666 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88314889, 1557036, 9298646; Product type r : regulator; repressor protein for FtsI complement(3031254..3032666) Escherichia fergusonii ATCC 35469 7119867 YP_002384063.1 CDS plsC NC_011740.1 3032735 3033472 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92212294, 1557036; Product type e : enzyme; 1-acyl-sn-glycerol-3-phosphate acyltransferase complement(3032735..3033472) Escherichia fergusonii ATCC 35469 7123404 YP_002384064.1 CDS parC NC_011740.1 3033724 3035982 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A complement(3033724..3035982) Escherichia fergusonii ATCC 35469 7120088 YP_002384065.1 CDS ygiW NC_011740.1 3036102 3036554 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9298646; hypothetical protein complement(3036102..3036554) Escherichia fergusonii ATCC 35469 7122556 YP_002384066.1 CDS qseB NC_011740.1 3036645 3037304 D response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes; DNA-binding transcriptional regulator QseB 3036645..3037304 Escherichia fergusonii ATCC 35469 7119870 YP_002384067.1 CDS qseC NC_011740.1 3037301 3038656 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11929534, 15919996; Product type r : regulator; sensor protein QseC 3037301..3038656 Escherichia fergusonii ATCC 35469 7122340 YP_002384068.1 CDS mdaB NC_011740.1 3038759 3039340 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96004656, 96217538; Product type c : carrier; NADPH quinone reductase 3038759..3039340 Escherichia fergusonii ATCC 35469 7124025 YP_002384069.1 CDS ygiN NC_011740.1 3039371 3039685 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10493123, 9298646, 9600841, 9868784; Product type e : enzyme; quinol monooxygenase 3039371..3039685 Escherichia fergusonii ATCC 35469 7121239 YP_002384070.1 CDS parE NC_011740.1 3039733 3041625 R decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B complement(3039733..3041625) Escherichia fergusonii ATCC 35469 7119869 YP_002384071.1 CDS yqiA NC_011740.1 3041654 3042235 R Displays esterase activity toward palmitoyl-CoA and pNP-butyrate; esterase YqiA complement(3041654..3042235) Escherichia fergusonii ATCC 35469 7122557 YP_002384072.1 CDS cpdA NC_011740.1 3042235 3043062 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96411758; Product type e : enzyme; cyclic 3',5'-adenosine monophosphate phosphodiesterase complement(3042235..3043062) Escherichia fergusonii ATCC 35469 7119731 YP_002384073.1 CDS yqiB NC_011740.1 3043087 3043509 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein complement(3043087..3043509) Escherichia fergusonii ATCC 35469 7124104 YP_002384074.1 CDS nudF NC_011740.1 3043509 3044138 R ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose pyrophosphatase NudF complement(3043509..3044138) Escherichia fergusonii ATCC 35469 7123586 YP_002384075.1 CDS tolC NC_011740.1 3044338 3045819 D trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell; outer membrane channel protein 3044338..3045819 Escherichia fergusonii ATCC 35469 7119671 YP_002384076.1 CDS ygiA NC_011740.1 3045819 3046076 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3045819..3046076 Escherichia fergusonii ATCC 35469 7122141 YP_002384077.1 CDS ygiB NC_011740.1 3046060 3046635 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3046060..3046635 Escherichia fergusonii ATCC 35469 7119862 YP_002384078.1 CDS ygiC NC_011740.1 3046641 3047801 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 3046641..3047801 Escherichia fergusonii ATCC 35469 7119863 YP_002384079.1 CDS assT NC_011740.1 3048324 3050120 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8887346, 11534764; Product type e : enzyme; arylsulfate sulfotransferase 3048324..3050120 Escherichia fergusonii ATCC 35469 7119864 YP_002384080.1 CDS dsbA NC_011740.1 3050136 3050804 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8887346, 10600454; Product type e : enzyme; Thiol:disulfide interchange protein dsbA 3050136..3050804 Escherichia fergusonii ATCC 35469 7120573 YP_002384081.1 CDS EFER_2982 NC_011740.1 3050819 3051490 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10600454; Product type pe : enzyme; disulfide oxidoreductase 3050819..3051490 Escherichia fergusonii ATCC 35469 7122921 YP_002384082.1 CDS zupT NC_011740.1 3051538 3052416 R seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine; hypothetical protein complement(3051538..3052416) Escherichia fergusonii ATCC 35469 7120417 YP_002384083.1 CDS ygiE NC_011740.1 3052468 3053241 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11790762, 1314093; Product type t : transporter; zinc transporter ZupT 3052468..3053241 Escherichia fergusonii ATCC 35469 7123421 YP_002384084.1 CDS EFER_2985 NC_011740.1 3053307 3053489 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3053307..3053489) Escherichia fergusonii ATCC 35469 7119865 YP_002384085.1 CDS ygiL NC_011740.1 3054045 3054608 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; fimbrial protein 3054045..3054608 Escherichia fergusonii ATCC 35469 7120418 YP_002384086.1 CDS yqiG NC_011740.1 3054695 3057217 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; outer membrane usher protein 3054695..3057217 Escherichia fergusonii ATCC 35469 7119868 YP_002384087.1 CDS yqiH NC_011740.1 3057224 3057973 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; periplasmic pilin chaperone 3057224..3057973 Escherichia fergusonii ATCC 35469 7123037 YP_002384088.1 CDS EFER_2989 NC_011740.1 3057970 3059013 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3057970..3059013 Escherichia fergusonii ATCC 35469 7123587 YP_002384089.1 CDS ribB NC_011740.1 3059067 3059720 R DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase complement(3059067..3059720) Escherichia fergusonii ATCC 35469 7120419 YP_002384090.1 CDS yqiC NC_011740.1 3060036 3060392 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3060036..3060392 Escherichia fergusonii ATCC 35469 7121405 YP_002384091.1 CDS glgS NC_011740.1 3060562 3060768 R Involved in glycogen synthesis. May be involved in glycogen priming; glycogen synthesis protein GlgS complement(3060562..3060768) Escherichia fergusonii ATCC 35469 7119732 YP_002384092.1 CDS yqiJ NC_011740.1 3061019 3061648 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15919996; Product type pm : membrane component; Inner membrane protein yqiJ 3061019..3061648 Escherichia fergusonii ATCC 35469 7120188 YP_002384093.1 CDS yqiK NC_011740.1 3061679 3063340 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3061679..3063340 Escherichia fergusonii ATCC 35469 7119733 YP_002384094.1 CDS EFER_2995 NC_011740.1 3063675 3063944 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3063675..3063944 Escherichia fergusonii ATCC 35469 7121182 YP_002384095.1 CDS rfaE NC_011740.1 3064510 3065943 R catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose; bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase complement(3064510..3065943) Escherichia fergusonii ATCC 35469 7121180 YP_002384096.1 CDS glnE NC_011740.1 3065991 3068831 R catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase complement(3065991..3068831) Escherichia fergusonii ATCC 35469 7123311 YP_002384097.1 CDS ygiF NC_011740.1 3068854 3070155 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8412694; Product type pe : enzyme; adenylate cyclase complement(3068854..3070155) Escherichia fergusonii ATCC 35469 7120196 YP_002384098.1 CDS EFER_2999 NC_011740.1 3070172 3070378 R Evidence 6 : Doubtful CDS; hypothetical protein complement(3070172..3070378) Escherichia fergusonii ATCC 35469 7123605 YP_002384099.1 CDS htrG NC_011740.1 3070397 3071017 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11274153; Product type pr : regulator; signal transduction protein 3070397..3071017 Escherichia fergusonii ATCC 35469 7120421 YP_002384100.1 CDS cca NC_011740.1 3071081 3072319 D catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases; multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase 3071081..3072319 Escherichia fergusonii ATCC 35469 7122233 YP_002384101.1 CDS bacA NC_011740.1 3072400 3073221 R BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase complement(3072400..3073221) Escherichia fergusonii ATCC 35469 7120864 YP_002384102.1 CDS folB NC_011740.1 3073312 3073680 R catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin; bifunctional dihydroneopterin aldolase/dihydroneopterin triphosphate 2'-epimerase complement(3073312..3073680) Escherichia fergusonii ATCC 35469 7123355 YP_002384103.1 CDS plsY NC_011740.1 3073786 3074403 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 3073786..3074403 Escherichia fergusonii ATCC 35469 7123569 YP_002384104.1 CDS gcp NC_011740.1 3074449 3075462 R in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease complement(3074449..3075462) Escherichia fergusonii ATCC 35469 7123101 YP_002384105.1 CDS rpsU NC_011740.1 3075700 3075915 D a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 3075700..3075915 Escherichia fergusonii ATCC 35469 7120177 YP_002384106.1 CDS dnaG NC_011740.1 3076027 3077772 D synthesizes RNA primers at the replication forks; DNA primase 3076027..3077772 Escherichia fergusonii ATCC 35469 7121140 YP_002384107.1 CDS rpoD NC_011740.1 3077967 3079808 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 3077967..3079808 Escherichia fergusonii ATCC 35469 7122911 YP_002384108.1 CDS EFER_3009 NC_011740.1 3079868 3080431 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3079868..3080431 Escherichia fergusonii ATCC 35469 7123811 YP_002384109.1 CDS ygjF NC_011740.1 3080488 3080994 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20412902, 99453007, 6269063, 7567469, 8878487, 9489705; Product type e : enzyme; G/U mismatch-specific DNA glycosylase complement(3080488..3080994) Escherichia fergusonii ATCC 35469 7123156 YP_002384110.1 CDS EFER_3011 NC_011740.1 3081311 3083278 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2531290, 8041620, 9278503, 2140572; Product type pf : factor; Selenocysteine-specific elongation factor complement(3081311..3083278) Escherichia fergusonii ATCC 35469 7120045 YP_002384111.1 CDS EFER_3012 NC_011740.1 3083232 3083627 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; GrdX protein complement(3083232..3083627) Escherichia fergusonii ATCC 35469 7120422 YP_002384112.1 CDS EFER_3013 NC_011740.1 3083673 3083897 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10091582, 8529639; Product type e : enzyme; glycine reductase complex component B subunit gamma complement(3083673..3083897) Escherichia fergusonii ATCC 35469 7120423 YP_002384113.1 CDS EFER_3014 NC_011740.1 3083925 3084971 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10091582, 8529639; Product type e : enzyme; glycine reductase complex component B subunit gamma complement(3083925..3084971) Escherichia fergusonii ATCC 35469 7120424 YP_002384114.1 CDS EFER_3015 NC_011740.1 3084985 3086274 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10091582, 8529639; Product type e : enzyme; glycine reductase complex component B subunits alpha/beta complement(3084985..3086274) Escherichia fergusonii ATCC 35469 7120425 YP_002384115.1 CDS EFER_3016 NC_011740.1 3086285 3087547 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11737196, 1587286; Product type e : enzyme; glycine/sarcosine/betaine reductase complex component C subunit alpha complement(3086285..3087547) Escherichia fergusonii ATCC 35469 7123157 YP_002384116.1 CDS EFER_3017 NC_011740.1 3087405 3088964 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8223622, 1587286; Product type e : enzyme; glycine/sarcosine/betaine reductase complex component C subunit beta complement(3087405..3088964) Escherichia fergusonii ATCC 35469 7123158 YP_002384117.1 CDS EFER_3018 NC_011740.1 3088985 3089314 R GrdA accepts a carboxymethylselenoether from protein B and transfers it to protein C forming a protein C-bound acetyl-thioester; oxidized GrdA is then reduced by thioredoxin; glycine/sarcosine/betaine reductase complex protein A complement(3088985..3089314) Escherichia fergusonii ATCC 35469 7120426 YP_002384118.1 CDS EFER_3019 NC_011740.1 3089330 3089458 R glycine/sarcosine/betaine reductase complex component A complement(3089330..3089458) Escherichia fergusonii ATCC 35469 7120427 YP_002384119.1 CDS EFER_3020 NC_011740.1 3089485 3089808 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; thioredoxin (TRX) complement(3089485..3089808) Escherichia fergusonii ATCC 35469 7120428 YP_002384120.1 CDS EFER_3021 NC_011740.1 3089805 3091100 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; thioredoxin-disulfide reductase complement(3089805..3091100) Escherichia fergusonii ATCC 35469 7120429 YP_002384121.1 CDS yqjH NC_011740.1 3091927 3092706 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; siderophore interacting protein complement(3091927..3092706) Escherichia fergusonii ATCC 35469 7123700 YP_002384122.1 CDS yqjI NC_011740.1 3092961 3093587 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator 3092961..3093587 Escherichia fergusonii ATCC 35469 7119739 YP_002384123.1 CDS aer NC_011740.1 3093662 3095182 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20015410, 9380671, 9643537, 9190831; Product type r : regulator; bifunctional signal transducer for aerotaxis sensory component/methyl accepting chemotaxis component complement(3093662..3095182) Escherichia fergusonii ATCC 35469 7123588 YP_002384124.1 CDS ygjG NC_011740.1 3095512 3096918 D catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate; putrescine--2-oxoglutarate aminotransferase 3095512..3096918 Escherichia fergusonii ATCC 35469 7122279 YP_002384125.1 CDS EFER_3026 NC_011740.1 3097083 3098267 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3097083..3098267 Escherichia fergusonii ATCC 35469 7123063 YP_002384126.1 CDS EFER_3027 NC_011740.1 3098261 3099301 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3098261..3099301) Escherichia fergusonii ATCC 35469 7123701 YP_002384127.1 CDS uxuR NC_011740.1 3099562 3100335 R regulates the expression of uxuBA; DNA-binding transcriptional repressor UxuR complement(3099562..3100335) Escherichia fergusonii ATCC 35469 7120430 YP_002384128.1 CDS uxuB NC_011740.1 3100580 3102046 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 73203083, 77222076, 14401695; Product type e : enzyme; D-mannonate oxidoreductase, NAD-binding complement(3100580..3102046) Escherichia fergusonii ATCC 35469 7122653 YP_002384129.1 CDS uxuA NC_011740.1 3102127 3103311 R catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase complement(3102127..3103311) Escherichia fergusonii ATCC 35469 7123514 YP_002384130.1 CDS slp NC_011740.1 3103820 3104386 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94293775, 8022277; Product type lp : lipoprotein; outer membrane lipoprotein 3103820..3104386 Escherichia fergusonii ATCC 35469 7122652 YP_002384131.1 CDS dctR NC_011740.1 3104745 3105308 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8022277, 8041620, 9811641, 12399493, 12900028, 12694615; Product type pe : enzyme; HTH-type transcriptional regulator 3104745..3105308 Escherichia fergusonii ATCC 35469 7123924 YP_002384132.1 CDS yhiD NC_011740.1 3105382 3106041 R inner membrane protein involved in cell density-dependent acid resistance; part of the acid fitness island (AFI) of E. coli; Mg(2+) transport ATPase complement(3105382..3106041) Escherichia fergusonii ATCC 35469 7122876 YP_002384133.1 CDS hdeB NC_011740.1 3106152 3106562 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8455549; acid-resistance protein complement(3106152..3106562) Escherichia fergusonii ATCC 35469 7122514 YP_002384134.1 CDS hdeA NC_011740.1 3106580 3106963 R inactive form; acid-resistance protein complement(3106580..3106963) Escherichia fergusonii ATCC 35469 7120633 YP_002384135.1 CDS hdeD NC_011740.1 3107165 3107734 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8455549; Product type pm : membrane component; acid-resistance membrane protein 3107165..3107734 Escherichia fergusonii ATCC 35469 7123193 YP_002384136.1 CDS gadE NC_011740.1 3108502 3109029 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8244952, 12399493, 12694615, 12940989, 14702398; Product type f : factor; transcriptional regulator gadE 3108502..3109029 Escherichia fergusonii ATCC 35469 7120634 YP_002384137.1 CDS mdtE NC_011740.1 3109149 3110438 D with MdtF and tolC is involved in resistance to rhodamine 6G, erythromycin, doxorubicin and other compounds; multidrug efflux system protein MdtE 3109149..3110438 Escherichia fergusonii ATCC 35469 7123655 YP_002384138.1 CDS mdtF NC_011740.1 3110464 3113577 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21450803; Product type t : transporter; multidrug transporter, RpoS-dependent 3110464..3113577 Escherichia fergusonii ATCC 35469 7121251 YP_002384139.1 CDS EFER_3040 NC_011740.1 3113619 3113783 R Evidence 6 : Doubtful CDS; hypothetical protein complement(3113619..3113783) Escherichia fergusonii ATCC 35469 7121252 YP_002384140.1 CDS gadW NC_011740.1 3113803 3114540 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8041620, 9278503, 12446650, 12730179, 14617649; Product type f : factor; AraC-type transcriptional regulator complement(3113803..3114540) Escherichia fergusonii ATCC 35469 7120431 YP_002384141.1 CDS EFER_3042 NC_011740.1 3115205 3116074 D regulates genes in response to acid and/or during stationary phase; DNA-binding transcriptional regulator GadX 3115205..3116074 Escherichia fergusonii ATCC 35469 7123115 YP_002384142.1 CDS EFER_3043 NC_011740.1 3116107 3117393 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8905232, 3038201, 1658595, 8387749, 10696472, 1429631, 10655611; Product type e : enzyme; phosphoanhydride phosphorylase 3116107..3117393 Escherichia fergusonii ATCC 35469 7120432 YP_002384143.1 CDS EFER_3044 NC_011740.1 3117514 3117807 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3117514..3117807 Escherichia fergusonii ATCC 35469 7120433 YP_002384144.1 CDS EFER_3045 NC_011740.1 3118010 3118195 D Evidence 6 : Doubtful CDS; hypothetical protein 3118010..3118195 Escherichia fergusonii ATCC 35469 7120434 YP_002384145.1 CDS EFER_3046 NC_011740.1 3118375 3118545 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3118375..3118545 Escherichia fergusonii ATCC 35469 7120435 YP_002384146.1 CDS EFER_3047 NC_011740.1 3118932 3119369 D Evidence 6 : Doubtful CDS; hypothetical protein 3118932..3119369 Escherichia fergusonii ATCC 35469 7120436 YP_002384147.1 CDS yhaM NC_011740.1 3119515 3120900 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3119515..3120900) Escherichia fergusonii ATCC 35469 7123159 YP_002384148.1 CDS tdcC NC_011740.1 3121115 3122446 R involved in the import of threonine and serine in combination with the import of a proton; threonine/serine transporter TdcC complement(3121115..3122446) Escherichia fergusonii ATCC 35469 7119878 YP_002384149.1 CDS tdcB NC_011740.1 3122468 3123457 R catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic; threonine dehydratase complement(3122468..3123457) Escherichia fergusonii ATCC 35469 7123407 YP_002384150.1 CDS yjiM NC_011740.1 3124175 3125326 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 3691501, 11106419; Product type pe : enzyme; 2-hydroxyglutaryl-CoA dehydratase 3124175..3125326 Escherichia fergusonii ATCC 35469 7123958 YP_002384151.1 CDS hgdC NC_011740.1 3125330 3126103 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8365476, 7607244, 15654892; Product type e : enzyme; ATPase, activator of (R)-hydroxyglutaryl-CoA dehydratase 3125330..3126103 Escherichia fergusonii ATCC 35469 7122030 YP_002384152.1 CDS EFER_3053 NC_011740.1 3125977 3126354 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3125977..3126354 Escherichia fergusonii ATCC 35469 7123440 YP_002384153.1 CDS fadH NC_011740.1 3126502 3128520 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12840019, 89380266; Product type e : enzyme; 2,4-dienoyl-CoA reductase 3126502..3128520 Escherichia fergusonii ATCC 35469 7120437 YP_002384154.1 CDS tsr NC_011740.1 3128702 3130513 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20015410, 89034150, 91317710, 10466731, 2033064, 6213619, 6402709, 8384293; Product type r : regulator; methyl-accepting chemotaxis protein I, serine sensor receptor complement(3128702..3130513) Escherichia fergusonii ATCC 35469 7123626 YP_002384155.1 CDS EFER_3056 NC_011740.1 3130505 3131410 D Evidence 2b : Function of strongly homologous gene; PubMedId : 14656965; Product type f : factor; transcriptional regulator 3130505..3131410 Escherichia fergusonii ATCC 35469 7122175 YP_002384156.1 CDS EFER_3057 NC_011740.1 3131420 3132889 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; Na+/proline symporter complement(3131420..3132889) Escherichia fergusonii ATCC 35469 7120438 YP_002384157.1 CDS EFER_3058 NC_011740.1 3132992 3133387 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3132992..3133387) Escherichia fergusonii ATCC 35469 7120439 YP_002384158.1 CDS EFER_3059 NC_011740.1 3133391 3134842 R Evidence 2b : Function of strongly homologous gene; PubMedId : 7763985; Product type e : enzyme; D-aminoacylase complement(3133391..3134842) Escherichia fergusonii ATCC 35469 7120440 YP_002384159.1 CDS EFER_3060 NC_011740.1 3135025 3136254 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; aldolase or racemase 3135025..3136254 Escherichia fergusonii ATCC 35469 7123160 YP_002384160.1 CDS hpaR NC_011740.1 3136344 3136784 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8384293, 8550403; Product type r : regulator; 4-hydroxyphenylacetate degradative operon repressor complement(3136344..3136784) Escherichia fergusonii ATCC 35469 7123161 YP_002384161.1 CDS hpaG NC_011740.1 3137055 3138350 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8223600, 8384293, 11863436; Product type e : enzyme; 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase 3137055..3138350 Escherichia fergusonii ATCC 35469 7122219 YP_002384162.1 CDS hpaE NC_011740.1 3138347 3139813 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7737515, 2061311, 8550403; Product type e : enzyme; 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase 3138347..3139813 Escherichia fergusonii ATCC 35469 7124002 YP_002384163.1 CDS hpaD NC_011740.1 3139815 3140666 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8550403; Product type e : enzyme; 3,4-dihydroxyphenylacetate 2,3-dioxygenase 3139815..3140666 Escherichia fergusonii ATCC 35469 7122215 YP_002384164.1 CDS hpaF NC_011740.1 3140676 3141056 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2194841; Product type e : enzyme; 5-carboxymethyl-2-hydroxymuconate delta-isomerase 3140676..3141056 Escherichia fergusonii ATCC 35469 7124001 YP_002384165.1 CDS hpaH NC_011740.1 3141106 3141927 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8550403, 9492273; Product type e : enzyme; 2-oxo-hepta-3-ene-1,7-dioic acid hydratase 3141106..3141927 Escherichia fergusonii ATCC 35469 7122216 YP_002384166.1 CDS hpaI NC_011740.1 3141797 3142726 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8529896, 8550403; Product type e : enzyme; 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 3141797..3142726 Escherichia fergusonii ATCC 35469 7122217 YP_002384167.1 CDS EFER_3068 NC_011740.1 3142850 3144226 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8550403, 14744977; Product type pt : transporter; 4-hydroxyphenylacetate permease 3142850..3144226 Escherichia fergusonii ATCC 35469 7122218 YP_002384168.1 CDS hpaA NC_011740.1 3144236 3145126 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8077235, 8550403; Product type r : regulator; Regulator of the 4HPA-hydroxylase operon 3144236..3145126 Escherichia fergusonii ATCC 35469 7120441 YP_002384169.1 CDS hpaB NC_011740.1 3145377 3146939 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8077235, 8550403, 10653707; Product type e : enzyme; 4-hydroxyphenylacetate 3-monooxygenase large component 3145377..3146939 Escherichia fergusonii ATCC 35469 7122212 YP_002384170.1 CDS hpaC NC_011740.1 3146957 3147469 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8077235, 8550403, 10633095; Product type e : enzyme; 4-hydroxyphenylacetate 3-monooxygenase small component 3146957..3147469 Escherichia fergusonii ATCC 35469 7122213 YP_002384171.1 CDS EFER_3072 NC_011740.1 3147548 3147694 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3147548..3147694 Escherichia fergusonii ATCC 35469 7122214 YP_002384172.1 CDS yjiY NC_011740.1 3147739 3149889 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3147739..3149889 Escherichia fergusonii ATCC 35469 7120442 YP_002384173.1 CDS yjiX NC_011740.1 3149939 3150142 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3149939..3150142 Escherichia fergusonii ATCC 35469 7122034 YP_002384174.1 CDS yjiA NC_011740.1 3150153 3151109 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14696199; Product type pe : enzyme; GTP-binding protein YjiA 3150153..3151109 Escherichia fergusonii ATCC 35469 7123969 YP_002384175.1 CDS EFER_3076 NC_011740.1 3151143 3151586 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3151143..3151586) Escherichia fergusonii ATCC 35469 7122029 YP_002384176.1 CDS EFER_3077 NC_011740.1 3151432 3151746 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3151432..3151746) Escherichia fergusonii ATCC 35469 7120443 YP_002384177.1 CDS EFER_3078 NC_011740.1 3151875 3152636 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3151875..3152636) Escherichia fergusonii ATCC 35469 7120444 YP_002384178.1 CDS hsdR NC_011740.1 3152872 3156384 D restriction endonuclease; the EcoKI enzyme recognizes 5'-AACN(6)GTGC-3'; subunit R is required for both nuclease and ATPase activities; type I restriction enzyme EcoKI subunit R 3152872..3156384 Escherichia fergusonii ATCC 35469 7123702 YP_002384179.1 CDS hsdM NC_011740.1 3156461 3158050 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88118919, 91216450, 3323532; Product type e : enzyme; DNA methylase M 3156461..3158050 Escherichia fergusonii ATCC 35469 7122225 YP_002384180.1 CDS EFER_3081 NC_011740.1 3158047 3159555 D Evidence 2b : Function of strongly homologous gene; PubMedId : 6304321; Product type e : enzyme; Specificity determinant for hsdM and hsdR 3158047..3159555 Escherichia fergusonii ATCC 35469 7122224 YP_002384181.1 CDS yjiW NC_011740.1 3159726 3160124 D involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response; endoribonuclease SymE 3159726..3160124 Escherichia fergusonii ATCC 35469 7121186 YP_002384182.1 CDS mcrB NC_011740.1 3160286 3161665 D McrB protein together with McrC forms the McrBC restriction system; recognizes N4- and C5-methylcytosine (and 5-hydroxy-methylcytosines); appears to act against 5-methylcytosine preceded by a purine residue; 5-methylcytosine-specific restriction enzyme subunit McrB 3160286..3161665 Escherichia fergusonii ATCC 35469 7122033 YP_002384183.1 CDS mcrC NC_011740.1 3161665 3162711 D McrC protein together with McrB forms the McrBC restriction system; recognizes N4- and C5-methylcytosine (and 5-hydroxy-methylcytosines); appears to act against 5-methylcytosine preceded by a purine residue; MrcC modulates the specificty of McrB and has DNA cleavage activity; 5-methylcytosine-specific restriction enzyme subunit McrC 3161665..3162711 Escherichia fergusonii ATCC 35469 7121237 YP_002384184.1 CDS EFER_3085 NC_011740.1 3162768 3169109 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3162768..3169109) Escherichia fergusonii ATCC 35469 7121238 YP_002384185.1 CDS yjgt NC_011740.1 3169122 3172460 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3169122..3172460) Escherichia fergusonii ATCC 35469 7120446 YP_002384186.1 CDS yjiS NC_011740.1 3172911 3173075 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3172911..3173075) Escherichia fergusonii ATCC 35469 7122026 YP_002384187.1 CDS yjiR NC_011740.1 3173252 3174664 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; bifunctional DNA-binding transcriptional regulator/aminotransferase 3173252..3174664 Escherichia fergusonii ATCC 35469 7123968 YP_002384188.1 CDS EFER_3089 NC_011740.1 3174908 3175828 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3174908..3175828) Escherichia fergusonii ATCC 35469 7123967 YP_002384189.1 CDS yjiO NC_011740.1 3176307 3177539 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21450803; Product type t : transporter; multidrug efflux system protein 3176307..3177539 Escherichia fergusonii ATCC 35469 7120447 YP_002384190.1 CDS yjiN NC_011740.1 3177580 3178860 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3177580..3178860 Escherichia fergusonii ATCC 35469 7122032 YP_002384191.1 CDS EFER_3092 NC_011740.1 3179250 3179441 D Evidence 7 : Gene remnant; Product type pe : enzyme; transposase (fragment) 3179250..3179441 Escherichia fergusonii ATCC 35469 7122031 YP_002384192.1 CDS EFER_3093 NC_011740.1 3179454 3179690 D Evidence 7 : Gene remnant; Product type pe : enzyme; transposase (fragment) 3179454..3179690 Escherichia fergusonii ATCC 35469 7120448 YP_002384193.1 CDS EFER_3094 NC_011740.1 3180144 3181613 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; protein kinase from phage origin complement(3180144..3181613) Escherichia fergusonii ATCC 35469 7120449 YP_002384194.1 CDS EFER_3095 NC_011740.1 3181610 3182209 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3181610..3182209) Escherichia fergusonii ATCC 35469 7122546 YP_002384195.1 CDS EFER_3096 NC_011740.1 3182160 3183845 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; nucleoside triphosphate hydrolase complement(3182160..3183845) Escherichia fergusonii ATCC 35469 7122426 YP_002384196.1 CDS EFER_3097 NC_011740.1 3183835 3184992 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3183835..3184992) Escherichia fergusonii ATCC 35469 7122427 YP_002384197.1 CDS EFER_3098 NC_011740.1 3184995 3185870 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3184995..3185870) Escherichia fergusonii ATCC 35469 7122428 YP_002384198.1 CDS EFER_3099 NC_011740.1 3185854 3190140 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3185854..3190140) Escherichia fergusonii ATCC 35469 7122429 YP_002384199.1 CDS EFER_3100 NC_011740.1 3190137 3191438 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3190137..3191438) Escherichia fergusonii ATCC 35469 7123478 YP_002384200.1 CDS EFER_3101 NC_011740.1 3191441 3193015 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; restriction modification system DNA specificity domain complement(3191441..3193015) Escherichia fergusonii ATCC 35469 7122430 YP_002384201.1 CDS EFER_3102 NC_011740.1 3193012 3195159 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; type I restriction-modification system methyltransferase subunit complement(3193012..3195159) Escherichia fergusonii ATCC 35469 7122431 YP_002384202.1 CDS EFER_3103 NC_011740.1 3195210 3195596 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3195210..3195596) Escherichia fergusonii ATCC 35469 7122432 YP_002384203.1 CDS EFER_3104 NC_011740.1 3195593 3196936 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; 5-methylcytosine restriction system component complement(3195593..3196936) Escherichia fergusonii ATCC 35469 7122433 YP_002384204.1 CDS EFER_3105 NC_011740.1 3196929 3199004 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7781618; Product type pe : enzyme; 5-methylcytosine-specific restriction enzyme with GTPase activity complement(3196929..3199004) Escherichia fergusonii ATCC 35469 7122434 YP_002384205.1 CDS EFER_3106 NC_011740.1 3199174 3200187 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3199174..3200187) Escherichia fergusonii ATCC 35469 7122435 YP_002384206.1 CDS EFER_3107 NC_011740.1 3199991 3200266 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3199991..3200266 Escherichia fergusonii ATCC 35469 7122436 YP_002384207.1 CDS EFER_3110 NC_011740.1 3201630 3202034 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3201630..3202034 Escherichia fergusonii ATCC 35469 7123215 YP_002384208.1 CDS yjgB NC_011740.1 3202109 3203128 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12147722; Product type pe : enzyme; alcohol dehydrogenase 3202109..3203128 Escherichia fergusonii ATCC 35469 7120068 YP_002384209.1 CDS EFER_3112 NC_011740.1 3203134 3203325 D Evidence 6 : Doubtful CDS; hypothetical protein 3203134..3203325 Escherichia fergusonii ATCC 35469 7123966 YP_002384210.1 CDS yjgR NC_011740.1 3203258 3204760 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; ATPase 3203258..3204760 Escherichia fergusonii ATCC 35469 7122437 YP_002384211.1 CDS yraQ NC_011740.1 3204867 3205907 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; permease complement(3204867..3205907) Escherichia fergusonii ATCC 35469 7122025 YP_002384212.1 CDS yraR NC_011740.1 3205980 3206615 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; nucleoside-diphosphate-sugar epimerase complement(3205980..3206615) Escherichia fergusonii ATCC 35469 7119742 YP_002384213.1 CDS yhbO NC_011740.1 3206743 3207261 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; intracellular protease 3206743..3207261 Escherichia fergusonii ATCC 35469 7119743 YP_002384214.1 CDS yhbP NC_011740.1 3207241 3207684 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3207241..3207684) Escherichia fergusonii ATCC 35469 7119882 YP_002384215.1 CDS yhbQ NC_011740.1 3207735 3208037 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; GIY-YIG nuclease superfamily protein 3207735..3208037 Escherichia fergusonii ATCC 35469 7123607 YP_002384216.1 CDS yhbS NC_011740.1 3208024 3208527 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; acyltransferase complement(3208024..3208527) Escherichia fergusonii ATCC 35469 7119883 YP_002384217.1 CDS yhbT NC_011740.1 3208521 3209045 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; lipid carrier protein complement(3208521..3209045) Escherichia fergusonii ATCC 35469 7119884 YP_002384218.1 CDS yhbU NC_011740.1 3209254 3210249 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10206698; Product type e : enzyme; peptidase 3209254..3210249 Escherichia fergusonii ATCC 35469 7119885 YP_002384219.1 CDS yhbV NC_011740.1 3210258 3211136 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10206698; Product type e : enzyme; protease 3210258..3211136 Escherichia fergusonii ATCC 35469 7119886 YP_002384220.1 CDS yhbW NC_011740.1 3211217 3212224 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 3211217..3212224 Escherichia fergusonii ATCC 35469 7123067 YP_002384221.1 CDS EFER_3124 NC_011740.1 3212202 3212942 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3212202..3212942) Escherichia fergusonii ATCC 35469 7119887 YP_002384222.1 CDS EFER_3125 NC_011740.1 3212874 3213107 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3212874..3213107 Escherichia fergusonii ATCC 35469 7122438 YP_002384223.1 CDS EFER_3126 NC_011740.1 3213257 3214144 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9128730; Product type pe : enzyme; triphosphoribosyl-dephospho-CoA transferase 3213257..3214144 Escherichia fergusonii ATCC 35469 7122439 YP_002384224.1 CDS EFER_3127 NC_011740.1 3214304 3215512 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9128730; Product type pt : transporter; carboxybiotin decarboxylase subunit of malonate decarboxylase 3214304..3215512 Escherichia fergusonii ATCC 35469 7122440 YP_002384225.1 CDS EFER_3128 NC_011740.1 3215525 3217192 D Evidence 2b : Function of strongly homologous gene; PubMedId : 9128730; Product type e : enzyme; Acetyl-S-acyl carrier protein: malonate acyl carrier protein-SH transferase 3215525..3217192 Escherichia fergusonii ATCC 35469 7124039 YP_002384226.1 CDS EFER_3129 NC_011740.1 3217204 3217536 D Evidence 2b : Function of strongly homologous gene; PubMedId : 9128730; Product type e : enzyme; Malonate decarboxylase acyl carrier protein 3217204..3217536 Escherichia fergusonii ATCC 35469 7123479 YP_002384227.1 CDS EFER_3130 NC_011740.1 3217391 3218458 D The beta subunit catalyzes the decarboxylation of the malonyl moiety on coenzyme A; malonate decarboxylase subunit beta 3217391..3218458 Escherichia fergusonii ATCC 35469 7122441 YP_002384228.1 CDS EFER_3131 NC_011740.1 3218458 3219339 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9128730; Product type pe : enzyme; subunit of malonyl-S-acyl carrier protein: biotin carboxyltransferase 3218458..3219339 Escherichia fergusonii ATCC 35469 7122442 YP_002384229.1 CDS EFER_3132 NC_011740.1 3219355 3220455 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9128730; Product type pc : carrier; acyl carrier protein-SH: acetate 3219355..3220455 Escherichia fergusonii ATCC 35469 7123480 YP_002384230.1 CDS EFER_3133 NC_011740.1 3220452 3221138 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9128730; hypothetical protein 3220452..3221138 Escherichia fergusonii ATCC 35469 7123481 YP_002384231.1 CDS EFER_3134 NC_011740.1 3221159 3221377 D Evidence 2b : Function of strongly homologous gene; PubMedId : 9128730; Product type e : enzyme; Biotin protein MadF 3221159..3221377 Escherichia fergusonii ATCC 35469 7122443 YP_002384232.1 CDS EFER_3135 NC_011740.1 3221682 3222062 D Evidence 2b : Function of strongly homologous gene; PubMedId : 9128730; Product type t : transporter; malonate transporter subunit MadL 3221682..3222062 Escherichia fergusonii ATCC 35469 7122444 YP_002384233.1 CDS EFER_3136 NC_011740.1 3222079 3222849 D Evidence 2b : Function of strongly homologous gene; PubMedId : 9128730; Product type t : transporter; malonate transporter subunit MadM 3222079..3222849 Escherichia fergusonii ATCC 35469 7122445 YP_002384234.1 CDS EFER_3137 NC_011740.1 3222893 3223324 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3222893..3223324 Escherichia fergusonii ATCC 35469 7122446 YP_002384235.1 CDS EFER_3138 NC_011740.1 3223287 3224228 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9208947; Product type f : factor; Malonate utilization transacting regulator MdcR complement(3223287..3224228) Escherichia fergusonii ATCC 35469 7122447 YP_002384236.1 CDS mtr NC_011740.1 3224328 3225572 R tryptophan transporter of high affinity; tryptophan permease complement(3224328..3225572) Escherichia fergusonii ATCC 35469 7122448 YP_002384237.1 CDS EFER_3140 NC_011740.1 3225573 3225725 D Evidence 6 : Doubtful CDS; hypothetical protein 3225573..3225725 Escherichia fergusonii ATCC 35469 7120641 YP_002384238.1 CDS deaD NC_011740.1 3225726 3227615 R participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division; ATP-dependent RNA helicase DeaD complement(3225726..3227615) Escherichia fergusonii ATCC 35469 7122449 YP_002384239.1 CDS nlpI NC_011740.1 3227795 3228679 R lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing; lipoprotein NlpI complement(3227795..3228679) Escherichia fergusonii ATCC 35469 7122881 YP_002384240.1 CDS pnp NC_011740.1 3228788 3230992 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87083499, 91198209, 99234021, 99340204, 2432069, 3005122, 6382163, 9008164, 9298646; Product type e : enzyme; polynucleotide phosphorylase/polyadenylase complement(3228788..3230992) Escherichia fergusonii ATCC 35469 7123026 YP_002384241.1 CDS rpsO NC_011740.1 3231169 3231438 R primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 complement(3231169..3231438) Escherichia fergusonii ATCC 35469 7123951 YP_002384242.1 CDS truB NC_011740.1 3231587 3232531 R catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B complement(3231587..3232531) Escherichia fergusonii ATCC 35469 7121136 YP_002384243.1 CDS rbfA NC_011740.1 3232531 3232932 R associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A complement(3232531..3232932) Escherichia fergusonii ATCC 35469 7123437 YP_002384244.1 CDS infB NC_011740.1 3233095 3235767 R Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 complement(3233095..3235767) Escherichia fergusonii ATCC 35469 7122346 YP_002384245.1 CDS nusA NC_011740.1 3235792 3237279 R modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA complement(3235792..3237279) Escherichia fergusonii ATCC 35469 7120738 YP_002384246.1 CDS yhbC NC_011740.1 3237307 3237759 R in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein complement(3237307..3237759) Escherichia fergusonii ATCC 35469 7119684 YP_002384247.1 CDS argG NC_011740.1 3238390 3239733 D catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; argininosuccinate synthase 3238390..3239733 Escherichia fergusonii ATCC 35469 7123639 YP_002384248.1 CDS yhbX NC_011740.1 3239777 3241378 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; inner membrane sulfatase YhbX complement(3239777..3241378) Escherichia fergusonii ATCC 35469 7123714 YP_002384249.1 CDS secG NC_011740.1 3241747 3242079 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20194819, 21125563, 9020118, 94074540, 9564033, 9644254, 9829959, 99298179, 7556084, 8034620, 8045257, 8244950, 8253068; Product type t : transporter; preprotein translocase subunit SecG complement(3241747..3242079) Escherichia fergusonii ATCC 35469 7123638 YP_002384250.1 CDS glmM NC_011740.1 3242307 3243644 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(3242307..3243644) Escherichia fergusonii ATCC 35469 7123373 YP_002384251.1 CDS folP NC_011740.1 3243637 3244485 R catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate; dihydropteroate synthase complement(3243637..3244485) Escherichia fergusonii ATCC 35469 7120191 YP_002384252.1 CDS hflB NC_011740.1 3244575 3246509 R inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; ATP-dependent metalloprotease complement(3244575..3246509) Escherichia fergusonii ATCC 35469 7123006 YP_002384253.1 CDS rrmJ NC_011740.1 3246609 3247238 R Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit; 23S rRNA methyltransferase J complement(3246609..3247238) Escherichia fergusonii ATCC 35469 7120148 YP_002384254.1 CDS yhbY NC_011740.1 3247364 3247657 D RNA binding protein found associated to pre-50S subunit of the ribosome; role in ribosome assembly; necessary for optimal growth but not cell viability; RNA-binding protein YhbY 3247364..3247657 Escherichia fergusonii ATCC 35469 7121143 YP_002384255.1 CDS greA NC_011740.1 3247813 3248289 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA complement(3247813..3248289) Escherichia fergusonii ATCC 35469 7119889 YP_002384256.1 CDS dacB NC_011740.1 3248537 3249970 D penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains; D-alanyl-D-alanine carboxypeptidase 3248537..3249970 Escherichia fergusonii ATCC 35469 7123188 YP_002384257.1 CDS obgE NC_011740.1 3250011 3251183 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(3250011..3251183) Escherichia fergusonii ATCC 35469 7122861 YP_002384258.1 CDS yhbE NC_011740.1 3251199 3252164 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(3251199..3252164) Escherichia fergusonii ATCC 35469 7119689 YP_002384259.1 CDS rpmA NC_011740.1 3252291 3252548 R involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 complement(3252291..3252548) Escherichia fergusonii ATCC 35469 7119880 YP_002384260.1 CDS rplU NC_011740.1 3252569 3252880 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91088242, 94146411, 10094780, 387076, 8312607; Product type s : structure; 50S ribosomal protein L21 complement(3252569..3252880) Escherichia fergusonii ATCC 35469 7121112 YP_002384261.1 CDS ispB NC_011740.1 3253140 3254111 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94311902, 97284515, 2670911, 8037730, 8312607; Product type e : enzyme; octaprenyl diphosphate synthase 3253140..3254111 Escherichia fergusonii ATCC 35469 7121108 YP_002384262.1 CDS sfsB NC_011740.1 3254312 3254635 D activator of maltose metabolism genes; DNA-binding transcriptional regulator Nlp 3254312..3254635 Escherichia fergusonii ATCC 35469 7120791 YP_002384263.1 CDS murA NC_011740.1 3254689 3255948 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(3254689..3255948) Escherichia fergusonii ATCC 35469 7121776 YP_002384264.1 CDS yrbA NC_011740.1 3256002 3256256 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator complement(3256002..3256256) Escherichia fergusonii ATCC 35469 7123194 YP_002384265.1 CDS yrbB NC_011740.1 3256382 3256675 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3256382..3256675) Escherichia fergusonii ATCC 35469 7119744 YP_002384266.1 CDS yrbC NC_011740.1 3256675 3257310 R Evidence 2b : Function of strongly homologous gene; PubMedId : 9658016; Product type t : transporter; toluene ABC transporter membrane protein complement(3256675..3257310) Escherichia fergusonii ATCC 35469 7119745 YP_002384267.1 CDS yrbD NC_011740.1 3257329 3257895 R Evidence 2b : Function of strongly homologous gene; PubMedId : 9658016; Product type t : transporter; toluene ABC transporter membrane protein complement(3257329..3257895) Escherichia fergusonii ATCC 35469 7119746 YP_002384268.1 CDS yrbE NC_011740.1 3257885 3258667 R Evidence 2b : Function of strongly homologous gene; PubMedId : 9658016; Product type t : transporter; toluene ABC transporter membrane protein complement(3257885..3258667) Escherichia fergusonii ATCC 35469 7119747 YP_002384269.1 CDS yrbF NC_011740.1 3258675 3259490 R ATP-binding subunit of a ABC toluene efflux transporter; ABC transporter ATP-binding protein complement(3258675..3259490) Escherichia fergusonii ATCC 35469 7119748 YP_002384270.1 CDS yrbG NC_011740.1 3259666 3260679 D YrbG; inner membrane protein involved in cell envelope integrity; sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers; calcium/sodium:proton antiporter 3259666..3260679 Escherichia fergusonii ATCC 35469 7119749 YP_002384271.1 CDS kdsD NC_011740.1 3260693 3261679 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12805358; Product type e : enzyme; D-arabinose 5-phosphate isomerase 3260693..3261679 Escherichia fergusonii ATCC 35469 7123042 YP_002384272.1 CDS kdsC NC_011740.1 3261697 3262263 D forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 3261697..3262263 Escherichia fergusonii ATCC 35469 7123225 YP_002384273.1 CDS yrbK NC_011740.1 3262260 3262835 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3262260..3262835 Escherichia fergusonii ATCC 35469 7123224 YP_002384274.1 CDS lptA NC_011740.1 3262804 3263361 D LptA; periplasmic binding protein part of a ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system; lipopolysaccharide transport periplasmic protein LptA 3262804..3263361 Escherichia fergusonii ATCC 35469 7123043 YP_002384275.1 CDS lptB NC_011740.1 3263368 3264093 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7876255, 9298646, 17056748; Product type pt : transporter; ABC transporter ATP-binding protein 3263368..3264093 Escherichia fergusonii ATCC 35469 7121196 YP_002384276.1 CDS rpoN NC_011740.1 3264141 3265574 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 3264141..3265574 Escherichia fergusonii ATCC 35469 7121198 YP_002384277.1 CDS yhbH NC_011740.1 3265597 3265884 D YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing; sigma(54) modulation protein 3265597..3265884 Escherichia fergusonii ATCC 35469 7121124 YP_002384278.1 CDS ptsN NC_011740.1 3266004 3266495 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88212176, 90136533, 90274974, 95020584, 95181483, 7876255, 8025669, 8444818, 9636714; Product type t : transporter; PTS system transporter subunit IIA-like nitrogen-regulatory protein PtsN 3266004..3266495 Escherichia fergusonii ATCC 35469 7123606 YP_002384279.1 CDS yhbJ NC_011740.1 3266541 3267395 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3266541..3267395 Escherichia fergusonii ATCC 35469 7122316 YP_002384280.1 CDS npr NC_011740.1 3267392 3267664 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10473571, 95181483, 7876255, 8025669; Product type t : transporter; PTS system phosphohistidinoprotein-hexose phosphotransferase Npr 3267392..3267664 Escherichia fergusonii ATCC 35469 7119881 YP_002384281.1 CDS yrbL NC_011740.1 3267861 3268493 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 89083480; hypothetical protein 3267861..3268493 Escherichia fergusonii ATCC 35469 7119657 YP_002384282.1 CDS mtgA NC_011740.1 3268490 3269215 R glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase complement(3268490..3269215) Escherichia fergusonii ATCC 35469 7119750 YP_002384283.1 CDS elbB NC_011740.1 3269212 3269865 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92246944, 98269038, 1575737, 9603997; Product type pe : enzyme; isoprenoid biosynthesis protein complement(3269212..3269865) Escherichia fergusonii ATCC 35469 7120389 YP_002384284.1 CDS arcB NC_011740.1 3270094 3272430 R sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA; aerobic respiration control sensor protein ArcB complement(3270094..3272430) Escherichia fergusonii ATCC 35469 7121183 YP_002384285.1 CDS yhcC NC_011740.1 3272525 3273454 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; Fe-S oxidoreductase complement(3272525..3273454) Escherichia fergusonii ATCC 35469 7120533 YP_002384286.1 CDS gltB NC_011740.1 3274027 3278580 D catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; glutamate synthase subunit alpha 3274027..3278580 Escherichia fergusonii ATCC 35469 7123068 YP_002384287.1 CDS gltD NC_011740.1 3278593 3280011 D glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 3278593..3280011 Escherichia fergusonii ATCC 35469 7120583 YP_002384288.1 CDS yhcG NC_011740.1 3280195 3281322 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3280195..3281322 Escherichia fergusonii ATCC 35469 7123185 YP_002384289.1 CDS yhcH NC_011740.1 3281382 3281846 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3281382..3281846) Escherichia fergusonii ATCC 35469 7119891 YP_002384290.1 CDS nanK NC_011740.1 3281843 3282718 R catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein; N-acetylmannosamine kinase complement(3281843..3282718) Escherichia fergusonii ATCC 35469 7119892 YP_002384291.1 CDS nanE NC_011740.1 3282715 3283404 R Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase complement(3282715..3283404) Escherichia fergusonii ATCC 35469 7120667 YP_002384292.1 CDS nanT NC_011740.1 3283451 3284941 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96011396, 9864311, 7592358; Product type t : transporter; sialic acid transporter complement(3283451..3284941) Escherichia fergusonii ATCC 35469 7120666 YP_002384293.1 CDS nanA NC_011740.1 3285050 3285943 R catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid; N-acetylneuraminate lyase complement(3285050..3285943) Escherichia fergusonii ATCC 35469 7120669 YP_002384294.1 CDS nanR NC_011740.1 3286065 3286847 R Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization; transcriptional regulator NanR complement(3286065..3286847) Escherichia fergusonii ATCC 35469 7120665 YP_002384295.1 CDS sspB NC_011740.1 3286965 3287468 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12445774, 94293773, 1721886, 3029697, 8022275; Product type f : factor; ClpXP protease specificity-enhancing factor complement(3286965..3287468) Escherichia fergusonii ATCC 35469 7120668 YP_002384296.1 CDS sspA NC_011740.1 3287474 3288112 R transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation; stringent starvation protein A complement(3287474..3288112) Escherichia fergusonii ATCC 35469 7123401 YP_002384297.1 CDS EFER_3200 NC_011740.1 3288194 3288370 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3288194..3288370 Escherichia fergusonii ATCC 35469 7123400 YP_002384298.1 CDS rpsI NC_011740.1 3288428 3288820 R forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 complement(3288428..3288820) Escherichia fergusonii ATCC 35469 7124040 YP_002384299.1 CDS rplM NC_011740.1 3288836 3289264 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(3288836..3289264) Escherichia fergusonii ATCC 35469 7123271 YP_002384300.1 CDS yhcM NC_011740.1 3289483 3290610 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3289483..3290610) Escherichia fergusonii ATCC 35469 7121103 YP_002384301.1 CDS yhcB NC_011740.1 3290804 3291202 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 16079137; Product type pe : enzyme; cytochrome d ubiquinol oxidase subunit III 3290804..3291202 Escherichia fergusonii ATCC 35469 7119893 YP_002384302.1 CDS degQ NC_011740.1 3291357 3292724 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8830688, 96165272, 8576051, 8576052, 9740056; Product type e : enzyme; serine endoprotease 3291357..3292724 Escherichia fergusonii ATCC 35469 7119890 YP_002384303.1 CDS degS NC_011740.1 3292814 3293881 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15137941, 15225661, 21352996, 96165272, 99431977, 3322223, 8576051; Product type e : enzyme; serine endoprotease 3292814..3293881 Escherichia fergusonii ATCC 35469 7123549 YP_002384304.1 CDS EFER_3207 NC_011740.1 3293909 3294085 R Evidence 4 : Homologs of previously reported genes of unknown function; oxaloacetate decarboxylase beta chain 1 (fragment) complement(3293909..3294085) Escherichia fergusonii ATCC 35469 7122885 YP_002384305.1 CDS EFER_3208 NC_011740.1 3294331 3294948 R Involved in the tartrate degradation pathway; L(+)-tartrate dehydratase subunit beta complement(3294331..3294948) Escherichia fergusonii ATCC 35469 7122450 YP_002384306.1 CDS ttdA NC_011740.1 3294948 3295847 R Involved in the tartrate degradation pathway; tartrate dehydratase subunit alpha complement(3294948..3295847) Escherichia fergusonii ATCC 35469 7122451 YP_002384307.1 CDS EFER_3210 NC_011740.1 3295879 3297189 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; charged metabolite transporter complement(3295879..3297189) Escherichia fergusonii ATCC 35469 7122177 YP_002384308.1 CDS EFER_3211 NC_011740.1 3297359 3298024 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; regulatory protein, gntR family complement(3297359..3298024) Escherichia fergusonii ATCC 35469 7122452 YP_002384309.1 CDS EFER_3212 NC_011740.1 3298011 3298802 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; GntR family transcriptional regulator complement(3298011..3298802) Escherichia fergusonii ATCC 35469 7122453 YP_002384310.1 CDS mdh NC_011740.1 3298780 3299718 R oxidizes malate to oxaloacetate; malate dehydrogenase complement(3298780..3299718) Escherichia fergusonii ATCC 35469 7124041 YP_002384311.1 CDS EFER_3214 NC_011740.1 3299825 3299995 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3299825..3299995) Escherichia fergusonii ATCC 35469 7121240 YP_002384312.1 CDS argR NC_011740.1 3300133 3300603 D regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor 3300133..3300603 Escherichia fergusonii ATCC 35469 7124042 YP_002384313.1 CDS yhcN NC_011740.1 3300957 3301220 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3300957..3301220 Escherichia fergusonii ATCC 35469 7120543 YP_002384314.1 CDS EFER_3217 NC_011740.1 3301278 3301661 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; barnase inhibitor complement(3301278..3301661) Escherichia fergusonii ATCC 35469 7119894 YP_002384315.1 CDS aaeB NC_011740.1 3301664 3303631 R with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeB complement(3301664..3303631) Escherichia fergusonii ATCC 35469 7122454 YP_002384316.1 CDS aaeA NC_011740.1 3303637 3304569 R with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate; p-hydroxybenzoic acid efflux subunit AaeA complement(3303637..3304569) Escherichia fergusonii ATCC 35469 7122245 YP_002384317.1 CDS aaeX NC_011740.1 3304577 3304780 R membrane protein AaeX; the gene is a member of the aaeXAB operon; hypothetical protein complement(3304577..3304780) Escherichia fergusonii ATCC 35469 7122244 YP_002384318.1 CDS aaeR NC_011740.1 3304964 3305893 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15489430; Product type r : regulator; DNA-binding transcriptional regulator 3304964..3305893 Escherichia fergusonii ATCC 35469 7122246 YP_002384319.1 CDS tldD NC_011740.1 3305973 3307418 R responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA; protease TldD complement(3305973..3307418) Escherichia fergusonii ATCC 35469 7123450 YP_002384320.1 CDS yhdP NC_011740.1 3307573 3311364 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10960106; Product type pm : membrane component; hypothetical protein complement(3307573..3311364) Escherichia fergusonii ATCC 35469 7123986 YP_002384321.1 CDS rng NC_011740.1 3311420 3312889 R involved in the processing of the 5'end of 16S rRNA; ribonuclease G complement(3311420..3312889) Escherichia fergusonii ATCC 35469 7123609 YP_002384322.1 CDS yhdE NC_011740.1 3312879 3313472 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(3312879..3313472) Escherichia fergusonii ATCC 35469 7121426 YP_002384323.1 CDS mreD NC_011740.1 3313490 3313978 R part of cell wall structural complex MreBCD; transmembrane component; rod shape-determining protein MreD complement(3313490..3313978) Escherichia fergusonii ATCC 35469 7123069 YP_002384324.1 CDS mreC NC_011740.1 3313978 3315042 R in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC complement(3313978..3315042) Escherichia fergusonii ATCC 35469 7120968 YP_002384325.1 CDS mreB NC_011740.1 3315108 3316151 R functions in MreBCD complex in some organisms; rod shape-determining protein MreB complement(3315108..3316151) Escherichia fergusonii ATCC 35469 7120967 YP_002384326.1 CDS csrD NC_011740.1 3316458 3318398 R regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules; regulatory protein CsrD complement(3316458..3318398) Escherichia fergusonii ATCC 35469 7120966 YP_002384327.1 CDS yhdH NC_011740.1 3318550 3319524 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; oxidoreductase 3318550..3319524 Escherichia fergusonii ATCC 35469 7122825 YP_002384328.1 CDS yedY NC_011740.1 3319622 3320626 D in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; sulfite oxidase subunit YedY 3319622..3320626 Escherichia fergusonii ATCC 35469 7119895 YP_002384329.1 CDS yedZ NC_011740.1 3320627 3321226 D in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; sulfite oxidase subunit YedZ 3320627..3321226 Escherichia fergusonii ATCC 35469 7121543 YP_002384330.1 CDS accB NC_011740.1 3321614 3322084 D composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 3321614..3322084 Escherichia fergusonii ATCC 35469 7121544 YP_002384331.1 CDS accC NC_011740.1 3322095 3323444 D an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 3322095..3323444 Escherichia fergusonii ATCC 35469 7122254 YP_002384332.1 CDS yhdT NC_011740.1 3323553 3323795 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3323553..3323795 Escherichia fergusonii ATCC 35469 7122255 YP_002384333.1 CDS panF NC_011740.1 3323785 3325236 D mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase; sodium/panthothenate symporter 3323785..3325236 Escherichia fergusonii ATCC 35469 7119898 YP_002384334.1 CDS prmA NC_011740.1 3325248 3326129 D methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase 3325248..3326129 Escherichia fergusonii ATCC 35469 7122555 YP_002384335.1 CDS dusB NC_011740.1 3326458 3327423 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 22095566, 1459953, 1547773, 2835774, 2837762, 8226664; Product type e : enzyme; tRNA-dihydrouridine synthase B 3326458..3327423 Escherichia fergusonii ATCC 35469 7120130 YP_002384336.1 CDS fis NC_011740.1 3327449 3327745 D Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription; DNA-binding protein Fis 3327449..3327745 Escherichia fergusonii ATCC 35469 7122928 YP_002384337.1 CDS yhdJ NC_011740.1 3327810 3328709 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15028690, 9073062; Product type e : enzyme; methyltransferase 3327810..3328709 Escherichia fergusonii ATCC 35469 7120019 YP_002384338.1 CDS EFER_3242 NC_011740.1 3328797 3328961 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3328797..3328961 Escherichia fergusonii ATCC 35469 7123608 YP_002384339.1 CDS EFER_3243 NC_011740.1 3328979 3329638 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator EnvR complement(3328979..3329638) Escherichia fergusonii ATCC 35469 7122455 YP_002384340.1 CDS acrE NC_011740.1 3330045 3331202 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94012493, 1720861; Product type lp : lipoprotein; hypothetical protein 3330045..3331202 Escherichia fergusonii ATCC 35469 7122456 YP_002384341.1 CDS acrF NC_011740.1 3331214 3334327 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94262163, 99449638, 1720861, 8407802; Product type t : transporter; multidrug efflux system protein 3331214..3334327 Escherichia fergusonii ATCC 35469 7122268 YP_002384342.1 CDS yhdV NC_011740.1 3334558 3334779 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3334558..3334779 Escherichia fergusonii ATCC 35469 7122269 YP_002384343.1 CDS aapJ NC_011740.1 3335230 3336147 D Evidence 2b : Function of strongly homologous gene; PubMedId : 8898392; Product type t : transporter; amino-acid ABC transporter periplasmic-binding protein 3335230..3336147 Escherichia fergusonii ATCC 35469 7123746 YP_002384344.1 CDS aapQ NC_011740.1 3336215 3337396 D Evidence 2b : Function of strongly homologous gene; PubMedId : 8898392; Product type t : transporter; amino-acid ABC transporter membrane protein 3336215..3337396 Escherichia fergusonii ATCC 35469 7122247 YP_002384345.1 CDS aapM NC_011740.1 3337406 3338509 D Evidence 2b : Function of strongly homologous gene; PubMedId : 8898392; Product type t : transporter; amino-acid ABC transporter membrane protein 3337406..3338509 Escherichia fergusonii ATCC 35469 7122250 YP_002384346.1 CDS aapP NC_011740.1 3338517 3339275 D Evidence 2b : Function of strongly homologous gene; PubMedId : 8809753, 8898392; Product type t : transporter; amino-acid ABC transporter ATP-binding protein 3338517..3339275 Escherichia fergusonii ATCC 35469 7122248 YP_002384347.1 CDS yrdA NC_011740.1 3345001 3345882 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3345001..3345882 Escherichia fergusonii ATCC 35469 7120386 YP_002384348.1 CDS aroE NC_011740.1 3346112 3346930 R AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase complement(3346112..3346930) Escherichia fergusonii ATCC 35469 7123044 YP_002384349.1 CDS yrdC NC_011740.1 3346935 3347507 R RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA; ribosome maturation factor complement(3346935..3347507) Escherichia fergusonii ATCC 35469 7120547 YP_002384350.1 CDS yrdD NC_011740.1 3347512 3348054 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; DNA topoisomerase complement(3347512..3348054) Escherichia fergusonii ATCC 35469 7119751 YP_002384351.1 CDS smg NC_011740.1 3348083 3348556 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8432722; hypothetical protein complement(3348083..3348556) Escherichia fergusonii ATCC 35469 7119752 YP_002384352.1 CDS smf NC_011740.1 3348528 3349652 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 8112305, 8432722; DNA protecting protein DprA complement(3348528..3349652) Escherichia fergusonii ATCC 35469 7121794 YP_002384353.1 CDS def NC_011740.1 3349782 3350291 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 3349782..3350291 Escherichia fergusonii ATCC 35469 7121793 YP_002384354.1 CDS fmt NC_011740.1 3350306 3351253 D modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 3350306..3351253 Escherichia fergusonii ATCC 35469 7122884 YP_002384355.1 CDS rsmB NC_011740.1 3351299 3352588 D catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase; 16S rRNA methyltransferase B 3351299..3352588 Escherichia fergusonii ATCC 35469 7122999 YP_002384356.1 CDS trkA NC_011740.1 3352610 3353986 D involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein 3352610..3353986 Escherichia fergusonii ATCC 35469 7121149 YP_002384357.1 CDS mscL NC_011740.1 3354116 3354526 D forms homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 3354116..3354526 Escherichia fergusonii ATCC 35469 7122157 YP_002384358.1 CDS yhdL NC_011740.1 3354523 3354741 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3354523..3354741) Escherichia fergusonii ATCC 35469 7120972 YP_002384359.1 CDS zntR NC_011740.1 3354797 3355222 R mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators; zinc-responsive transcriptional regulator complement(3354797..3355222) Escherichia fergusonii ATCC 35469 7119896 YP_002384360.1 CDS yhdN NC_011740.1 3355233 3355601 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3355233..3355601) Escherichia fergusonii ATCC 35469 7119774 YP_002384361.1 CDS rplQ NC_011740.1 3355708 3356091 R is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 complement(3355708..3356091) Escherichia fergusonii ATCC 35469 7119897 YP_002384362.1 CDS rpoA NC_011740.1 3356132 3357121 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(3356132..3357121) Escherichia fergusonii ATCC 35469 7123809 YP_002384363.1 CDS rpsD NC_011740.1 3357147 3357767 R primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 complement(3357147..3357767) Escherichia fergusonii ATCC 35469 7121119 YP_002384364.1 CDS rpsK NC_011740.1 3357801 3358190 R located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 complement(3357801..3358190) Escherichia fergusonii ATCC 35469 7121129 YP_002384365.1 CDS rpsM NC_011740.1 3358207 3358563 R located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 complement(3358207..3358563) Escherichia fergusonii ATCC 35469 7121134 YP_002384366.1 CDS secY NC_011740.1 3358858 3360189 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(3358858..3360189) Escherichia fergusonii ATCC 35469 7123273 YP_002384367.1 CDS rplO NC_011740.1 3360197 3360631 R late assembly protein; 50S ribosomal protein L15 complement(3360197..3360631) Escherichia fergusonii ATCC 35469 7121765 YP_002384368.1 CDS rpmD NC_011740.1 3360635 3360814 R L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 complement(3360635..3360814) Escherichia fergusonii ATCC 35469 7121104 YP_002384369.1 CDS rpsE NC_011740.1 3360818 3361321 R located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 complement(3360818..3361321) Escherichia fergusonii ATCC 35469 7121115 YP_002384370.1 CDS rplR NC_011740.1 3361336 3361689 R binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 complement(3361336..3361689) Escherichia fergusonii ATCC 35469 7121130 YP_002384371.1 CDS rplF NC_011740.1 3361699 3362232 R ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 complement(3361699..3362232) Escherichia fergusonii ATCC 35469 7121105 YP_002384372.1 CDS rpsH NC_011740.1 3362245 3362637 R binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 complement(3362245..3362637) Escherichia fergusonii ATCC 35469 7123370 YP_002384373.1 CDS rpsN NC_011740.1 3362671 3362976 R located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 complement(3362671..3362976) Escherichia fergusonii ATCC 35469 7123270 YP_002384374.1 CDS rplE NC_011740.1 3362991 3363530 R part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 complement(3362991..3363530) Escherichia fergusonii ATCC 35469 7121135 YP_002384375.1 CDS rplX NC_011740.1 3363545 3363859 R assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 complement(3363545..3363859) Escherichia fergusonii ATCC 35469 7121441 YP_002384376.1 CDS rplN NC_011740.1 3363870 3364241 R binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 complement(3363870..3364241) Escherichia fergusonii ATCC 35469 7121110 YP_002384377.1 CDS rpsQ NC_011740.1 3364406 3364660 R primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 complement(3364406..3364660) Escherichia fergusonii ATCC 35469 7123267 YP_002384378.1 CDS rpmC NC_011740.1 3364660 3364851 R one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 complement(3364660..3364851) Escherichia fergusonii ATCC 35469 7121138 YP_002384379.1 CDS rplP NC_011740.1 3364851 3365261 R located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 complement(3364851..3365261) Escherichia fergusonii ATCC 35469 7121114 YP_002384380.1 CDS rpsC NC_011740.1 3365274 3365975 R forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 complement(3365274..3365975) Escherichia fergusonii ATCC 35469 7123808 YP_002384381.1 CDS rplV NC_011740.1 3365993 3366325 R binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 complement(3365993..3366325) Escherichia fergusonii ATCC 35469 7121128 YP_002384382.1 CDS rpsS NC_011740.1 3366340 3366618 R protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 complement(3366340..3366618) Escherichia fergusonii ATCC 35469 7121109 YP_002384383.1 CDS rplB NC_011740.1 3366635 3367456 R one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 complement(3366635..3367456) Escherichia fergusonii ATCC 35469 7121139 YP_002384384.1 CDS rplW NC_011740.1 3367474 3367776 R binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 complement(3367474..3367776) Escherichia fergusonii ATCC 35469 7121439 YP_002384385.1 CDS rplD NC_011740.1 3367773 3368378 R L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 complement(3367773..3368378) Escherichia fergusonii ATCC 35469 7123810 YP_002384386.1 CDS rplC NC_011740.1 3368389 3369018 R binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 complement(3368389..3369018) Escherichia fergusonii ATCC 35469 7121440 YP_002384387.1 CDS rpsJ NC_011740.1 3369051 3369362 R NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 complement(3369051..3369362) Escherichia fergusonii ATCC 35469 7123320 YP_002384388.1 CDS EFER_3306 NC_011740.1 3369741 3370214 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; bifunctional prepilin peptidase HopD: leader peptidase; methyl transferase 3369741..3370214 Escherichia fergusonii ATCC 35469 7121133 YP_002384389.1 CDS bfr NC_011740.1 3370204 3370680 R iron storage protein; bacterioferritin complement(3370204..3370680) Escherichia fergusonii ATCC 35469 7122457 YP_002384390.1 CDS bfd NC_011740.1 3370753 3370947 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8954950, 9889981, 2661540, 8639572; Product type c : carrier; bacterioferritin-associated ferredoxin complement(3370753..3370947) Escherichia fergusonii ATCC 35469 7123358 YP_002384391.1 CDS tufA NC_011740.1 3371130 3372314 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(3371130..3372314) Escherichia fergusonii ATCC 35469 7121659 YP_002384392.1 CDS fusA NC_011740.1 3372385 3374499 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(3372385..3374499) Escherichia fergusonii ATCC 35469 7123993 YP_002384393.1 CDS rpsG NC_011740.1 3374596 3375066 R binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 complement(3374596..3375066) Escherichia fergusonii ATCC 35469 7123114 YP_002384394.1 CDS rpsL NC_011740.1 3375163 3375537 R interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 complement(3375163..3375537) Escherichia fergusonii ATCC 35469 7121132 YP_002384395.1 CDS tusB NC_011740.1 3375663 3375950 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusB complement(3375663..3375950) Escherichia fergusonii ATCC 35469 7123272 YP_002384396.1 CDS tusC NC_011740.1 3375958 3376317 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC complement(3375958..3376317) Escherichia fergusonii ATCC 35469 7122607 YP_002384397.1 CDS tusD NC_011740.1 3376317 3376703 R in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD complement(3376317..3376703) Escherichia fergusonii ATCC 35469 7122608 YP_002384398.1 CDS yheO NC_011740.1 3376703 3377425 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator complement(3376703..3377425) Escherichia fergusonii ATCC 35469 7122609 YP_002384399.1 CDS fkpA NC_011740.1 3377592 3378404 R rotamase; FKBP-type peptidyl-prolyl cis-trans isomerase complement(3377592..3378404) Escherichia fergusonii ATCC 35469 7122486 YP_002384400.1 CDS slyX NC_011740.1 3378624 3378842 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3378624..3378842 Escherichia fergusonii ATCC 35469 7120024 YP_002384401.1 CDS slyD NC_011740.1 3378891 3379481 R rotamase; FKBP-type peptidyl-prolyl cis-trans isomerase complement(3378891..3379481) Escherichia fergusonii ATCC 35469 7123925 YP_002384402.1 CDS yheV NC_011740.1 3379576 3379776 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3379576..3379776) Escherichia fergusonii ATCC 35469 7121792 YP_002384403.1 CDS kefB NC_011740.1 3379786 3381591 R involved in potassium efflux; glutathione-regulated potassium-efflux system protein KefB complement(3379786..3381591) Escherichia fergusonii ATCC 35469 7122490 YP_002384404.1 CDS kefG NC_011740.1 3381591 3382145 R required for KefB activity; glutathione-regulated potassium-efflux system ancillary protein KefG complement(3381591..3382145) Escherichia fergusonii ATCC 35469 7120812 YP_002384405.1 CDS yheS NC_011740.1 3382273 3384186 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter ATP-binding protein 3382273..3384186 Escherichia fergusonii ATCC 35469 7123226 YP_002384406.1 CDS yheT NC_011740.1 3384186 3385208 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9889164; Product type pe : enzyme; hydrolase 3384186..3385208 Escherichia fergusonii ATCC 35469 7122487 YP_002384407.1 CDS yheU NC_011740.1 3385202 3385420 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3385202..3385420 Escherichia fergusonii ATCC 35469 7122488 YP_002384408.1 CDS EFER_3327 NC_011740.1 3385461 3385535 R hypothetical protein complement(3385461..3385535) Escherichia fergusonii ATCC 35469 7122489 YP_002384409.1 CDS prkB NC_011740.1 3385474 3386343 D Evidence 2b : Function of strongly homologous gene; PubMedId : 2559876; Product type e : enzyme; phosphoribulokinase 3385474..3386343 Escherichia fergusonii ATCC 35469 7123482 YP_002384410.1 CDS yhfA NC_011740.1 3386398 3386802 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3386398..3386802) Escherichia fergusonii ATCC 35469 7120128 YP_002384411.1 CDS crp NC_011740.1 3387107 3387739 D complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; cAMP-regulatory protein 3387107..3387739 Escherichia fergusonii ATCC 35469 7123537 YP_002384412.1 CDS yhfK NC_011740.1 3387778 3389880 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3387778..3389880 Escherichia fergusonii ATCC 35469 7122808 YP_002384413.1 CDS argD NC_011740.1 3389958 3391178 R DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase complement(3389958..3391178) Escherichia fergusonii ATCC 35469 7122491 YP_002384414.1 CDS pabA NC_011740.1 3391264 3391827 R aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; para-aminobenzoate synthase component II complement(3391264..3391827) Escherichia fergusonii ATCC 35469 7123177 YP_002384415.1 CDS fic NC_011740.1 3391859 3392461 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92021789, 94095125, 2007139, 2403545, 2546924, 7549107; Product type cp : cell process; cell filamentation protein Fic complement(3391859..3392461) Escherichia fergusonii ATCC 35469 7124060 YP_002384416.1 CDS yhfG NC_011740.1 3392451 3392618 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3392451..3392618) Escherichia fergusonii ATCC 35469 7120017 YP_002384417.1 CDS ppiA NC_011740.1 3392723 3393295 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90272647, 91175755, 1606970, 2001362, 2007139, 2190212, 2403545, 2546924, 8130188, 8180197; Product type e : enzyme; peptidyl-prolyl cis-trans isomerase A complement(3392723..3393295) Escherichia fergusonii ATCC 35469 7124048 YP_002384418.1 CDS nirB NC_011740.1 3393684 3396227 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93062014, 2200672, 2445993, 2543955; Product type e : enzyme; nitrite reductase, large subunit 3393684..3396227 Escherichia fergusonii ATCC 35469 7120113 YP_002384419.1 CDS nirD NC_011740.1 3396224 3396550 D involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations; nitrite reductase small subunit 3396224..3396550 Escherichia fergusonii ATCC 35469 7123205 YP_002384420.1 CDS nirC NC_011740.1 3396677 3397483 D member of the FNT family of formate and nitrite transporters; nitrite transporter NirC 3396677..3397483 Escherichia fergusonii ATCC 35469 7120696 YP_002384421.1 CDS cysG NC_011740.1 3397502 3398875 D multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin; siroheme synthase 3397502..3398875 Escherichia fergusonii ATCC 35469 7120695 YP_002384422.1 CDS yhfL NC_011740.1 3399125 3399292 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3399125..3399292 Escherichia fergusonii ATCC 35469 7122850 YP_002384423.1 CDS yhfS NC_011740.1 3399399 3400484 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3399399..3400484) Escherichia fergusonii ATCC 35469 7122492 YP_002384424.1 CDS yhfT NC_011740.1 3400496 3401800 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(3400496..3401800) Escherichia fergusonii ATCC 35469 7124049 YP_002384425.1 CDS yhfU NC_011740.1 3401812 3402165 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3401812..3402165) Escherichia fergusonii ATCC 35469 7122493 YP_002384426.1 CDS php NC_011740.1 3402176 3403054 R phosphotriesterase homology protein; PhP; YhfV; member of a family of proteins related to phosphotriesterase (PTE); hydrolase complement(3402176..3403054) Escherichia fergusonii ATCC 35469 7122494 YP_002384427.1 CDS yhfW NC_011740.1 3403051 3404277 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; mutase complement(3403051..3404277) Escherichia fergusonii ATCC 35469 7122605 YP_002384428.1 CDS yhfX NC_011740.1 3404277 3405440 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; amino acid racemase complement(3404277..3405440) Escherichia fergusonii ATCC 35469 7122495 YP_002384429.1 CDS yhfY NC_011740.1 3405524 3405886 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3405524..3405886) Escherichia fergusonii ATCC 35469 7122496 YP_002384430.1 CDS yhfZ NC_011740.1 3405903 3406808 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3405903..3406808) Escherichia fergusonii ATCC 35469 7122497 YP_002384431.1 CDS trpS NC_011740.1 3406969 3407973 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(3406969..3407973) Escherichia fergusonii ATCC 35469 7122498 YP_002384432.1 CDS gph NC_011740.1 3407966 3408724 R catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase complement(3407966..3408724) Escherichia fergusonii ATCC 35469 7122168 YP_002384433.1 CDS rpe NC_011740.1 3408717 3409394 R catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase complement(3408717..3409394) Escherichia fergusonii ATCC 35469 7120608 YP_002384434.1 CDS dam NC_011740.1 3409412 3410248 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90136529, 92262475, 92272672, 2549371, 6300769, 7603433, 8341592; Product type e : enzyme; DNA adenine methylase complement(3409412..3410248) Escherichia fergusonii ATCC 35469 7121434 YP_002384435.1 CDS damX NC_011740.1 3410365 3411645 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3410365..3411645) Escherichia fergusonii ATCC 35469 7122864 YP_002384436.1 CDS aroB NC_011740.1 3411737 3412825 R catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase complement(3411737..3412825) Escherichia fergusonii ATCC 35469 7122865 YP_002384437.1 CDS aroK NC_011740.1 3412883 3413404 R type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I complement(3412883..3413404) Escherichia fergusonii ATCC 35469 7120545 YP_002384438.1 CDS hofQ NC_011740.1 3413872 3415152 R outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa; outer membrane porin HofQ complement(3413872..3415152) Escherichia fergusonii ATCC 35469 7120551 YP_002384439.1 CDS EFER_3358 NC_011740.1 3415022 3415426 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3415022..3415426) Escherichia fergusonii ATCC 35469 7122207 YP_002384440.1 CDS EFER_3359 NC_011740.1 3415416 3416024 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3415416..3416024) Escherichia fergusonii ATCC 35469 7123483 YP_002384441.1 CDS EFER_3360 NC_011740.1 3415858 3416397 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3415858..3416397) Escherichia fergusonii ATCC 35469 7122458 YP_002384442.1 CDS yrfD NC_011740.1 3416397 3417221 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; pilus assembly protein complement(3416397..3417221) Escherichia fergusonii ATCC 35469 7122459 YP_002384443.1 CDS mrcA NC_011740.1 3417297 3419849 D bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits; peptidoglycan synthetase 3417297..3419849 Escherichia fergusonii ATCC 35469 7119753 YP_002384444.1 CDS nudE NC_011740.1 3419982 3420542 R ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose; ADP-ribose diphosphatase NudE complement(3419982..3420542) Escherichia fergusonii ATCC 35469 7123248 YP_002384445.1 CDS igaA NC_011740.1 3420865 3423000 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11553591; Product type r : regulator; intracellular growth attenuator protein 3420865..3423000 Escherichia fergusonii ATCC 35469 7123029 YP_002384446.1 CDS yrfG NC_011740.1 3423065 3423733 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hydrolase 3423065..3423733 Escherichia fergusonii ATCC 35469 7123742 YP_002384447.1 CDS hslR NC_011740.1 3423744 3424145 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9867837, 10675343, 10675344; Product type f : factor; ribosome-associated heat shock protein Hsp15 3423744..3424145 Escherichia fergusonii ATCC 35469 7119754 YP_002384448.1 CDS hslO NC_011740.1 3424170 3425048 D becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 3424170..3425048 Escherichia fergusonii ATCC 35469 7122228 YP_002384449.1 CDS yhgE NC_011740.1 3425088 3426821 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3425088..3426821) Escherichia fergusonii ATCC 35469 7122227 YP_002384450.1 CDS pck NC_011740.1 3427186 3428808 D PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 3427186..3428808 Escherichia fergusonii ATCC 35469 7123487 YP_002384451.1 CDS EFER_3370 NC_011740.1 3428924 3429241 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3428924..3429241 Escherichia fergusonii ATCC 35469 7122564 YP_002384452.1 CDS EFER_3371 NC_011740.1 3429299 3429595 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2404279; Product type pr : regulator; HTH-type transcriptional regulator yiaG 3429299..3429595 Escherichia fergusonii ATCC 35469 7122460 YP_002384453.1 CDS envZ NC_011740.1 3429627 3430979 R membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR; osmolarity sensor protein complement(3429627..3430979) Escherichia fergusonii ATCC 35469 7122461 YP_002384454.1 CDS ompR NC_011740.1 3430976 3431695 R part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; osmolarity response regulator complement(3430976..3431695) Escherichia fergusonii ATCC 35469 7122954 YP_002384455.1 CDS greB NC_011740.1 3431923 3432399 D necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreB 3431923..3432399 Escherichia fergusonii ATCC 35469 7123578 YP_002384456.1 CDS yhgF NC_011740.1 3432496 3434817 D Evidence 2b : Function of strongly homologous gene; PubMedId : 8755871; Product type f : factor; transcriptional accessory protein 3432496..3434817 Escherichia fergusonii ATCC 35469 7120614 YP_002384457.1 CDS feoA NC_011740.1 3435254 3435481 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94012482, 8407793; Product type t : transporter; ferrous iron transport protein A 3435254..3435481 Escherichia fergusonii ATCC 35469 7123488 YP_002384458.1 CDS feoB NC_011740.1 3435498 3437819 D cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake; ferrous iron transport protein B 3435498..3437819 Escherichia fergusonii ATCC 35469 7120003 YP_002384459.1 CDS yhgG NC_011740.1 3437819 3438055 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator 3437819..3438055 Escherichia fergusonii ATCC 35469 7120004 YP_002384460.1 CDS yhgA NC_011740.1 3438257 3439150 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2678009; Product type ph : phenotype; hypothetical protein 3438257..3439150 Escherichia fergusonii ATCC 35469 7122500 YP_002384461.1 CDS bioH NC_011740.1 3439370 3440140 R Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis; carboxylesterase BioH complement(3439370..3440140) Escherichia fergusonii ATCC 35469 7122499 YP_002384462.1 CDS gntX NC_011740.1 3440178 3440861 D involved in high-affinity gluconate transport; gluconate periplasmic binding protein 3440178..3440861 Escherichia fergusonii ATCC 35469 7121670 YP_002384463.1 CDS gntY NC_011740.1 3440921 3441496 D cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source; DNA uptake protein 3440921..3441496 Escherichia fergusonii ATCC 35469 7120600 YP_002384464.1 CDS gntT NC_011740.1 3441813 3443129 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 172599, 4574689, 4582156, 93139975, 97141270, 98019089, 2845225, 3040894, 7984428, 9045817; Product type t : transporter; gluconate transporter, high-affinity GNT I system 3441813..3443129 Escherichia fergusonii ATCC 35469 7120601 YP_002384465.1 CDS malQ NC_011740.1 3443174 3445258 R amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase complement(3443174..3445258) Escherichia fergusonii ATCC 35469 7120598 YP_002384466.1 CDS malP NC_011740.1 3445268 3447661 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 89033892, 10220320, 10469642, 2845225, 3037809, 3155826, 6283313, 6339728, 6986282, 9009262; Product type e : enzyme; maltodextrin phosphorylase complement(3445268..3447661) Escherichia fergusonii ATCC 35469 7123830 YP_002384467.1 CDS malT NC_011740.1 3448272 3450977 D Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides; transcriptional regulator MalT 3448272..3450977 Escherichia fergusonii ATCC 35469 7123288 YP_002384468.1 CDS rtcA NC_011740.1 3451020 3452036 R catalyzes the conversion of terminal3'-phosphate of RNA to the 2',3'-cyclicphosphodiester; RNA 3'-terminal-phosphate cyclase complement(3451020..3452036) Escherichia fergusonii ATCC 35469 7121227 YP_002384469.1 CDS rtcB NC_011740.1 3452040 3453266 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9738023; hypothetical protein complement(3452040..3453266) Escherichia fergusonii ATCC 35469 7121160 YP_002384470.1 CDS rtcR NC_011740.1 3453455 3455053 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9738023, 3045764, 7920643, 7984428; Product type r : regulator; sigma 54-dependent transcriptional regulator of rtcBA expression 3453455..3455053 Escherichia fergusonii ATCC 35469 7121161 YP_002384471.1 CDS glpR NC_011740.1 3455035 3455793 R represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism; DNA-binding transcriptional repressor GlpR complement(3455035..3455793) Escherichia fergusonii ATCC 35469 7123276 YP_002384472.1 CDS glpG NC_011740.1 3455810 3456640 R protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity; intramembrane serine protease GlpG complement(3455810..3456640) Escherichia fergusonii ATCC 35469 7123184 YP_002384473.1 CDS glpE NC_011740.1 3456685 3457011 R belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine; thiosulfate sulfurtransferase complement(3456685..3457011) Escherichia fergusonii ATCC 35469 7120578 YP_002384474.1 CDS glpD NC_011740.1 3457201 3458706 D in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 3457201..3458706 Escherichia fergusonii ATCC 35469 7120576 YP_002384475.1 CDS EFER_3395 NC_011740.1 3458738 3459190 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3458738..3459190) Escherichia fergusonii ATCC 35469 7120452 YP_002384476.1 CDS EFER_3396 NC_011740.1 3459203 3460255 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; ankyrin repeat-containing protein complement(3459203..3460255) Escherichia fergusonii ATCC 35469 7123484 YP_002384477.1 CDS EFER_3397 NC_011740.1 3460335 3461900 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter component complement(3460335..3461900) Escherichia fergusonii ATCC 35469 7122462 YP_002384478.1 CDS EFER_3398 NC_011740.1 3462034 3463185 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; fimbrial adhesin complement(3462034..3463185) Escherichia fergusonii ATCC 35469 7122463 YP_002384479.1 CDS EFER_3399 NC_011740.1 3463178 3463978 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; periplasmic pilin chaperone complement(3463178..3463978) Escherichia fergusonii ATCC 35469 7122464 YP_002384480.1 CDS EFER_3400 NC_011740.1 3463920 3464444 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; fimbrial-like adhesin protein complement(3463920..3464444) Escherichia fergusonii ATCC 35469 7122465 YP_002384481.1 CDS EFER_3401 NC_011740.1 3464452 3465024 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; fimbrial minor structural subunit complement(3464452..3465024) Escherichia fergusonii ATCC 35469 7122466 YP_002384482.1 CDS EFER_3402 NC_011740.1 3465015 3467606 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15213132; Product type pf : factor; outer membrane export usher protein aufC complement(3465015..3467606) Escherichia fergusonii ATCC 35469 7122467 YP_002384483.1 CDS EFER_3403 NC_011740.1 3467647 3468399 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; fimbria chaperone protein complement(3467647..3468399) Escherichia fergusonii ATCC 35469 7124043 YP_002384484.1 CDS aufA NC_011740.1 3468519 3469223 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15213132; Product type s : structure; Auf fimbriae major fimbrial subunit AufA complement(3468519..3469223) Escherichia fergusonii ATCC 35469 7122468 YP_002384485.1 CDS glgP NC_011740.1 3469713 3472160 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88330897, 91104907, 91236706, 2645169, 2975249, 3047129, 3097003; Product type e : enzyme; glycogen phosphorylase complement(3469713..3472160) Escherichia fergusonii ATCC 35469 7121640 YP_002384486.1 CDS glgA NC_011740.1 3472180 3473613 R catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase complement(3472180..3473613) Escherichia fergusonii ATCC 35469 7120187 YP_002384487.1 CDS glgC NC_011740.1 3473613 3474908 R catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase complement(3473613..3474908) Escherichia fergusonii ATCC 35469 7120185 YP_002384488.1 CDS glgX NC_011740.1 3474924 3476900 R catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen; glycogen debranching protein complement(3474924..3476900) Escherichia fergusonii ATCC 35469 7123118 YP_002384489.1 CDS glgB NC_011740.1 3476897 3479083 R catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein complement(3476897..3479083) Escherichia fergusonii ATCC 35469 7120189 YP_002384490.1 CDS asd NC_011740.1 3479354 3480565 R catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase complement(3479354..3480565) Escherichia fergusonii ATCC 35469 7120186 YP_002384491.1 CDS yhgN NC_011740.1 3480650 3481243 D YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP); dITP- and XTP- hydrolase 3480650..3481243 Escherichia fergusonii ATCC 35469 7120563 YP_002384492.1 CDS gntU NC_011740.1 3481300 3482640 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8655507, 9119199, 9135111, 97141270; Product type t : transporter; low affinity gluconate transporter complement(3481300..3482640) Escherichia fergusonii ATCC 35469 7122501 YP_002384493.1 CDS gntK NC_011740.1 3482644 3483171 R thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate; gluconate kinase complement(3482644..3483171) Escherichia fergusonii ATCC 35469 7120599 YP_002384494.1 CDS gntR NC_011740.1 3483310 3484305 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 172599, 9135111, 93139975, 9537375, 8655507; Product type r : regulator; DNA-binding transcriptional repressor complement(3483310..3484305) Escherichia fergusonii ATCC 35469 7120596 YP_002384495.1 CDS yhhW NC_011740.1 3484398 3485093 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3484398..3485093) Escherichia fergusonii ATCC 35469 7120597 YP_002384496.1 CDS yhhX NC_011740.1 3485216 3486253 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10493123; Product type pe : enzyme; dehydrogenase complement(3485216..3486253) Escherichia fergusonii ATCC 35469 7122511 YP_002384497.1 CDS yhhY NC_011740.1 3486587 3487075 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; acetyltransferase 3486587..3487075 Escherichia fergusonii ATCC 35469 7123823 YP_002384498.1 CDS yrhB NC_011740.1 3487185 3487469 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3487185..3487469 Escherichia fergusonii ATCC 35469 7122513 YP_002384499.1 CDS ggt NC_011740.1 3487507 3489318 R periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides; gamma-glutamyltranspeptidase complement(3487507..3489318) Escherichia fergusonii ATCC 35469 7119755 YP_002384500.1 CDS yhhA NC_011740.1 3489373 3489813 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3489373..3489813 Escherichia fergusonii ATCC 35469 7120183 YP_002384501.1 CDS ugpQ NC_011740.1 3489800 3490543 R hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate; glycerophosphodiester phosphodiesterase complement(3489800..3490543) Escherichia fergusonii ATCC 35469 7122502 YP_002384502.1 CDS ugpC NC_011740.1 3490540 3491610 R part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit complement(3490540..3491610) Escherichia fergusonii ATCC 35469 7122628 YP_002384503.1 CDS ugpE NC_011740.1 3491612 3492457 R with UgpABC is involved in uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter membrane protein complement(3491612..3492457) Escherichia fergusonii ATCC 35469 7122627 YP_002384504.1 CDS ugpA NC_011740.1 3492454 3493341 R with UgpEC is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter permease complement(3492454..3493341) Escherichia fergusonii ATCC 35469 7123508 YP_002384505.1 CDS ugpB NC_011740.1 3493439 3494755 R with UgpACE is involved in the uptake of glycerol-3-phosphate; glycerol-3-phosphate transporter periplasmic binding protein complement(3493439..3494755) Escherichia fergusonii ATCC 35469 7122625 YP_002384506.1 CDS EFER_3426 NC_011740.1 3494988 3495734 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3494988..3495734) Escherichia fergusonii ATCC 35469 7122626 YP_002384507.1 CDS livF NC_011740.1 3495853 3496566 R with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit complement(3495853..3496566) Escherichia fergusonii ATCC 35469 7122469 YP_002384508.1 CDS livG NC_011740.1 3496568 3497335 R Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter ATP-binding subunit complement(3496568..3497335) Escherichia fergusonii ATCC 35469 7120836 YP_002384509.1 CDS livM NC_011740.1 3497332 3498609 R Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine; leucine/isoleucine/valine transporter permease subunit complement(3497332..3498609) Escherichia fergusonii ATCC 35469 7123230 YP_002384510.1 CDS livH NC_011740.1 3498606 3499532 R LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter; branched-chain amino acid transporter permease subunit LivH complement(3498606..3499532) Escherichia fergusonii ATCC 35469 7120840 YP_002384511.1 CDS livK NC_011740.1 3499580 3500689 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14702302, 90307651, 2195019, 2649683, 3891753, 4077929, 9298646, 9298646; Product type t : transporter; leucine ABC transporter periplasmic-binding protein complement(3499580..3500689) Escherichia fergusonii ATCC 35469 7120837 YP_002384512.1 CDS yhhK NC_011740.1 3501113 3501496 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3501113..3501496 Escherichia fergusonii ATCC 35469 7120839 YP_002384513.1 CDS livJ NC_011740.1 3501697 3502800 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14702302, 90307651, 2195019, 2649682, 328304, 3891753, 4077929, 9298646, 10972807; Product type t : transporter; leucine/isoleucine/valine ABC transporter periplasmic-binding protein complement(3501697..3502800) Escherichia fergusonii ATCC 35469 7122506 YP_002384514.1 CDS rpoH NC_011740.1 3503072 3503926 R binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 complement(3503072..3503926) Escherichia fergusonii ATCC 35469 7120838 YP_002384515.1 CDS ftsX NC_011740.1 3504171 3505229 R ABC transporter, membrane protein; cell division protein FtsX complement(3504171..3505229) Escherichia fergusonii ATCC 35469 7121123 YP_002384516.1 CDS ftsE NC_011740.1 3505222 3505890 R ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions; cell division protein FtsE complement(3505222..3505890) Escherichia fergusonii ATCC 35469 7120151 YP_002384517.1 CDS ftsY NC_011740.1 3505893 3507431 R signal recognition protein receptor; functions in the targeting and insertion of membrane proteins; cell division protein FtsY complement(3505893..3507431) Escherichia fergusonii ATCC 35469 7123111 YP_002384518.1 CDS rsmD NC_011740.1 3507581 3508177 D catalyzes the methylation of 16S rRNA at position G966; 16S rRNA m(2)G966-methyltransferase 3507581..3508177 Escherichia fergusonii ATCC 35469 7123653 YP_002384519.1 CDS EFER_3439 NC_011740.1 3508044 3508436 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3508044..3508436 Escherichia fergusonii ATCC 35469 7122503 YP_002384520.1 CDS yhhM NC_011740.1 3508439 3508798 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3508439..3508798) Escherichia fergusonii ATCC 35469 7122470 YP_002384521.1 CDS yhhN NC_011740.1 3508939 3509565 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3508939..3509565 Escherichia fergusonii ATCC 35469 7122507 YP_002384522.1 CDS zntA NC_011740.1 3509639 3511840 D P-type ATPase involved in the export of lead, cadmium, zinc and mercury; zinc/cadmium/mercury/lead-transporting ATPase 3509639..3511840 Escherichia fergusonii ATCC 35469 7124052 YP_002384523.1 CDS EFER_3443 NC_011740.1 3511877 3512443 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3511877..3512443 Escherichia fergusonii ATCC 35469 7119773 YP_002384524.1 CDS tusA NC_011740.1 3512556 3512801 R TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA complement(3512556..3512801) Escherichia fergusonii ATCC 35469 7122471 YP_002384525.1 CDS yhhQ NC_011740.1 3513005 3513670 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3513005..3513670 Escherichia fergusonii ATCC 35469 7124071 YP_002384526.1 CDS dcrB NC_011740.1 3513689 3514300 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12558182, 8752353; Product type t : transporter; hypothetical protein 3513689..3514300 Escherichia fergusonii ATCC 35469 7122508 YP_002384527.1 CDS yhhS NC_011740.1 3514304 3515551 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter complement(3514304..3515551) Escherichia fergusonii ATCC 35469 7122872 YP_002384528.1 CDS yhhT NC_011740.1 3515641 3516690 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3515641..3516690 Escherichia fergusonii ATCC 35469 7122509 YP_002384529.1 CDS EFER_3449 NC_011740.1 3517082 3517474 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; lipoprotein 3517082..3517474 Escherichia fergusonii ATCC 35469 7122510 YP_002384530.1 CDS EFER_3450 NC_011740.1 3517535 3518602 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; methyltransferase 3517535..3518602 Escherichia fergusonii ATCC 35469 7124044 YP_002384531.1 CDS EFER_3451 NC_011740.1 3518642 3519367 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3518642..3519367 Escherichia fergusonii ATCC 35469 7124045 YP_002384532.1 CDS EFER_3452 NC_011740.1 3519346 3520179 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; 1-acylglycerol-3-phosphate O-acyltransferase 3519346..3520179 Escherichia fergusonii ATCC 35469 7122472 YP_002384533.1 CDS EFER_3453 NC_011740.1 3519968 3520417 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; acyl carrier protein component 3519968..3520417 Escherichia fergusonii ATCC 35469 7122473 YP_002384534.1 CDS EFER_3454 NC_011740.1 3520429 3520680 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 3520429..3520680 Escherichia fergusonii ATCC 35469 7122474 YP_002384535.1 CDS EFER_3455 NC_011740.1 3520685 3521266 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 3520685..3521266 Escherichia fergusonii ATCC 35469 7122475 YP_002384536.1 CDS EFER_3456 NC_011740.1 3521224 3522624 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; fatty acid degradation enzyme 3521224..3522624 Escherichia fergusonii ATCC 35469 7123485 YP_002384537.1 CDS EFER_3457 NC_011740.1 3522581 3522964 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; fatty acid degradation enzyme 3522581..3522964 Escherichia fergusonii ATCC 35469 7123486 YP_002384538.1 CDS EFER_3458 NC_011740.1 3522955 3524631 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; acyltransferase 3522955..3524631 Escherichia fergusonii ATCC 35469 7122476 YP_002384539.1 CDS EFER_3459 NC_011740.1 3524635 3525057 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; thioesterase 3524635..3525057 Escherichia fergusonii ATCC 35469 7122477 YP_002384540.1 CDS EFER_3460 NC_011740.1 3525054 3525659 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; outer membrane lipoprotein carrier protein 3525054..3525659 Escherichia fergusonii ATCC 35469 7122478 YP_002384541.1 CDS EFER_3461 NC_011740.1 3525628 3527946 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter 3525628..3527946 Escherichia fergusonii ATCC 35469 7122479 YP_002384542.1 CDS EFER_3462 NC_011740.1 3527943 3528527 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; lipoprotein 3527943..3528527 Escherichia fergusonii ATCC 35469 7122480 YP_002384543.1 CDS EFER_3463 NC_011740.1 3528520 3529698 D FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 3528520..3529698 Escherichia fergusonii ATCC 35469 7122481 YP_002384544.1 CDS EFER_3464 NC_011740.1 3529695 3530144 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; 3-hydroxy-fatty acyl-(acyl carrier protein) dehydratase 3529695..3530144 Escherichia fergusonii ATCC 35469 7122482 YP_002384545.1 CDS fabG NC_011740.1 3530159 3530890 D Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 3530159..3530890 Escherichia fergusonii ATCC 35469 7124046 YP_002384546.1 CDS EFER_3466 NC_011740.1 3530887 3532116 D FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 3530887..3532116 Escherichia fergusonii ATCC 35469 7122483 YP_002384547.1 CDS acpT NC_011740.1 3532118 3532702 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; holo-(acyl carrier protein) synthase 2 3532118..3532702 Escherichia fergusonii ATCC 35469 7122484 YP_002384548.1 CDS nikR NC_011740.1 3532742 3533143 D Inhibits transcription at high concentrations of nickel; nickel responsive regulator 3532742..3533143 Escherichia fergusonii ATCC 35469 7122264 YP_002384549.1 CDS EFER_3469 NC_011740.1 3533247 3534113 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 3533247..3534113 Escherichia fergusonii ATCC 35469 7123736 YP_002384550.1 CDS EFER_3470 NC_011740.1 3534453 3535208 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator 3534453..3535208 Escherichia fergusonii ATCC 35469 7121442 YP_002384551.1 CDS EFER_3471 NC_011740.1 3535233 3535706 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; phosphotransferase system enzyme subunit IIA 3535233..3535706 Escherichia fergusonii ATCC 35469 7120145 YP_002384552.1 CDS EFER_3472 NC_011740.1 3535703 3535984 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; phosphotransferase system enzyme IIB 3535703..3535984 Escherichia fergusonii ATCC 35469 7120269 YP_002384553.1 CDS EFER_3473 NC_011740.1 3536031 3537419 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; phosphotransferase system permease IIC 3536031..3537419 Escherichia fergusonii ATCC 35469 7120270 YP_002384554.1 CDS EFER_3474 NC_011740.1 3537412 3538920 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; carbohydrate kinase 3537412..3538920 Escherichia fergusonii ATCC 35469 7120271 YP_002384555.1 CDS EFER_3475 NC_011740.1 3538910 3539179 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; phosphocarrier HPr protein of a carbohydrate phosphotransferase system 3538910..3539179 Escherichia fergusonii ATCC 35469 7120272 YP_002384556.1 CDS gatY NC_011740.1 3539210 3540061 D class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis; fructose-1,6-bisphosphate aldolase 3539210..3540061 Escherichia fergusonii ATCC 35469 7123131 YP_002384557.1 CDS yhhJ NC_011740.1 3540152 3541276 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ABC transporter membrane protein complement(3540152..3541276) Escherichia fergusonii ATCC 35469 7120273 YP_002384558.1 CDS rbbA NC_011740.1 3541276 3544011 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20074572; Product type e : enzyme; ribosome-associated ATPase/membrane protein complement(3541276..3544011) Escherichia fergusonii ATCC 35469 7122505 YP_002384559.1 CDS yhiI NC_011740.1 3544008 3545075 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; HlyD family secretion protein complement(3544008..3545075) Escherichia fergusonii ATCC 35469 7123467 YP_002384560.1 CDS yhiM NC_011740.1 3545808 3546860 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3545808..3546860 Escherichia fergusonii ATCC 35469 7123489 YP_002384561.1 CDS siiEB NC_011740.1 3547731 3556922 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17220313, 15522082; Product type f : factor; adhesin for cattle intestine colonization 3547731..3556922 Escherichia fergusonii ATCC 35469 7123490 YP_002384562.1 CDS siiCB NC_011740.1 3556999 3558402 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17220313, 15522082, 2905265; Product type t : transporter; outer membrane export protein 3556999..3558402 Escherichia fergusonii ATCC 35469 7121787 YP_002384563.1 CDS siiBB NC_011740.1 3558399 3560576 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17220313, 15522082, 2905265, 2185213; Product type t : transporter; type I secretion membrane protein, ATP-binding protein, protein export 3558399..3560576 Escherichia fergusonii ATCC 35469 7123375 YP_002384564.1 CDS siiDB NC_011740.1 3560557 3561747 D Evidence 2b : Function of strongly homologous gene; PubMedId : 17220313, 15522082, 2905265; Product type t : transporter; HlyD family secretion type I protein 3560557..3561747 Escherichia fergusonii ATCC 35469 7121783 YP_002384565.1 CDS yhiN NC_011740.1 3561870 3563063 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; oxidoreductase complement(3561870..3563063) Escherichia fergusonii ATCC 35469 7123923 YP_002384566.1 CDS pitA NC_011740.1 3563293 3564792 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87014120; Product type t : transporter; phosphate transporter, low-affinity 3563293..3564792 Escherichia fergusonii ATCC 35469 7122515 YP_002384567.1 CDS yhiO NC_011740.1 3564844 3565179 R ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress; universal stress protein UspB complement(3564844..3565179) Escherichia fergusonii ATCC 35469 7123100 YP_002384568.1 CDS uspA NC_011740.1 3565572 3566006 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12732303, 93086426, 93308072, 94203056, 10499297, 10652104, 10931298, 11157932, 1453957, 8506346, 8932299, 9298646, 9405142; Product type f : factor; universal stress global response regulator 3565572..3566006 Escherichia fergusonii ATCC 35469 7122516 YP_002384569.1 CDS yhiP NC_011740.1 3566250 3567719 D member of the POT family of peptide transporters; probable proton-dependent peptide transporter function; inner membrane transporter YhiP 3566250..3567719 Escherichia fergusonii ATCC 35469 7122643 YP_002384570.1 CDS yhiQ NC_011740.1 3567768 3568520 R predicted SAM-dependent methyltransferase; methyltransferase complement(3567768..3568520) Escherichia fergusonii ATCC 35469 7123491 YP_002384571.1 CDS prlC NC_011740.1 3568528 3570570 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92394891, 1325967, 8366062; Product type e : enzyme; oligopeptidase A complement(3568528..3570570) Escherichia fergusonii ATCC 35469 7123492 YP_002384572.1 CDS yhiR NC_011740.1 3570773 3571615 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11591672; Product type pe : enzyme; DNA (exogenous) processing protein 3570773..3571615 Escherichia fergusonii ATCC 35469 7120129 YP_002384573.1 CDS gor NC_011740.1 3571687 3573039 D catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 3571687..3573039 Escherichia fergusonii ATCC 35469 7122517 YP_002384574.1 CDS EFER_3494 NC_011740.1 3573198 3573377 D Evidence 6 : Doubtful CDS; hypothetical protein 3573198..3573377 Escherichia fergusonii ATCC 35469 7120602 YP_002384575.1 CDS EFER_3495 NC_011740.1 3573256 3573423 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3573256..3573423 Escherichia fergusonii ATCC 35469 7120274 YP_002384576.1 CDS EFER_3496 NC_011740.1 3573448 3573672 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3573448..3573672 Escherichia fergusonii ATCC 35469 7120275 YP_002384577.1 CDS arsR NC_011740.1 3573918 3574271 D regulates the expression of of the arsRBC involved in resistance to arsenic; DNA-binding transcriptional repressor ArsR 3573918..3574271 Escherichia fergusonii ATCC 35469 7120276 YP_002384578.1 CDS arsB NC_011740.1 3574326 3575615 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15004242, 95355341, 1535622, 7721697; Product type t : transporter; arsenite/antimonite transporter 3574326..3575615 Escherichia fergusonii ATCC 35469 7120555 YP_002384579.1 CDS arsC NC_011740.1 3575628 3576053 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95355341, 7721697; Product type e : enzyme; arsenate reductase 3575628..3576053 Escherichia fergusonii ATCC 35469 7123718 YP_002384580.1 CDS EFER_3500 NC_011740.1 3576074 3576394 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3576074..3576394) Escherichia fergusonii ATCC 35469 7123719 YP_002384581.1 CDS EFER_3501 NC_011740.1 3576490 3577503 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein 3576490..3577503 Escherichia fergusonii ATCC 35469 7123671 YP_002384582.1 CDS treF NC_011740.1 3577746 3579395 D cytoplasmic; catalyzes the hydrolysis of trehalose to glucose; trehalase 3577746..3579395 Escherichia fergusonii ATCC 35469 7120277 YP_002384583.1 CDS yhjB NC_011740.1 3579428 3580111 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; HTH-type transcriptional regulator YhjB complement(3579428..3580111) Escherichia fergusonii ATCC 35469 7122156 YP_002384584.1 CDS EFER_3504 NC_011740.1 3580434 3580607 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3580434..3580607 Escherichia fergusonii ATCC 35469 7122518 YP_002384585.1 CDS yhjD NC_011740.1 3580564 3581619 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3580564..3581619 Escherichia fergusonii ATCC 35469 7120278 YP_002384586.1 CDS yhjE NC_011740.1 3581893 3583215 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter 3581893..3583215 Escherichia fergusonii ATCC 35469 7122519 YP_002384587.1 CDS yhjG NC_011740.1 3583256 3585316 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; outer membrane biogenesis protein complement(3583256..3585316) Escherichia fergusonii ATCC 35469 7122520 YP_002384588.1 CDS yhjH NC_011740.1 3585383 3586150 R in Escherichia coli this protein is involved in flagellar function; EAL domain-containing protein complement(3585383..3586150) Escherichia fergusonii ATCC 35469 7124053 YP_002384589.1 CDS kdgK NC_011740.1 3586356 3587285 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 4359651, 13813474; Product type e : enzyme; ketodeoxygluconokinase 3586356..3587285 Escherichia fergusonii ATCC 35469 7124054 YP_002384590.1 CDS EFER_3510 NC_011740.1 3587375 3588595 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3587375..3588595 Escherichia fergusonii ATCC 35469 7120803 YP_002384591.1 CDS EFER_3511 NC_011740.1 3588357 3590576 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3588357..3590576 Escherichia fergusonii ATCC 35469 7123672 YP_002384592.1 CDS yhjJ NC_011740.1 3591448 3592944 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9298646; Product type pe : enzyme; zinc-dependent peptidase complement(3591448..3592944) Escherichia fergusonii ATCC 35469 7120279 YP_002384593.1 CDS dctA NC_011740.1 3593166 3594452 R involved in the transport of C4-dicarboxylates across the membrane; C4-dicarboxylate transporter DctA complement(3593166..3594452) Escherichia fergusonii ATCC 35469 7122521 YP_002384594.1 CDS yhjK NC_011740.1 3594621 3596570 R HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a phosphodiesterase protein from E. coli; phosphodiesterase complement(3594621..3596570) Escherichia fergusonii ATCC 35469 7122873 YP_002384595.1 CDS bcsC NC_011740.1 3596685 3600158 R cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA; cellulose synthase subunit BcsC complement(3596685..3600158) Escherichia fergusonii ATCC 35469 7122522 YP_002384596.1 CDS bcsZ NC_011740.1 3600140 3601246 R catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans; endo-1,4-D-glucanase complement(3600140..3601246) Escherichia fergusonii ATCC 35469 7121652 YP_002384597.1 CDS bcsB NC_011740.1 3601253 3603592 R binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP); cellulose synthase regulator protein complement(3601253..3603592) Escherichia fergusonii ATCC 35469 7123902 YP_002384598.1 CDS bcsA NC_011740.1 3603603 3606221 R polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis; cellulose synthase catalytic subunit complement(3603603..3606221) Escherichia fergusonii ATCC 35469 7121651 YP_002384599.1 CDS yhjQ NC_011740.1 3606218 3606985 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9054507; Product type pe : enzyme; chromosome partitioning ATPase complement(3606218..3606985) Escherichia fergusonii ATCC 35469 7121649 YP_002384600.1 CDS yhjR NC_011740.1 3606997 3607185 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3606997..3607185) Escherichia fergusonii ATCC 35469 7122523 YP_002384601.1 CDS bcsE NC_011740.1 3607472 3609031 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11929533, 11260463; Product type pe : enzyme; cellulose biosynthesis protease 3607472..3609031 Escherichia fergusonii ATCC 35469 7122524 YP_002384602.1 CDS bcsF NC_011740.1 3609028 3609219 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3609028..3609219 Escherichia fergusonii ATCC 35469 7121653 YP_002384603.1 CDS bcsG NC_011740.1 3609216 3610895 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11929533, 11260463; Product type pe : enzyme; cellulose biosynthesis endoglucanase 3609216..3610895 Escherichia fergusonii ATCC 35469 7121654 YP_002384604.1 CDS EFER_3527 NC_011740.1 3611464 3611715 R Small toxic polypeptide ldrD complement(3611464..3611715) Escherichia fergusonii ATCC 35469 7121655 YP_002384605.1 CDS EFER_3528 NC_011740.1 3611815 3612057 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3611815..3612057 Escherichia fergusonii ATCC 35469 7123673 YP_002384606.1 CDS ldrD NC_011740.1 3611946 3612188 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12123448; Product type f : factor; toxic polypeptide, small complement(3611946..3612188) Escherichia fergusonii ATCC 35469 7120280 YP_002384607.1 CDS EFER_3530 NC_011740.1 3612298 3612540 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3612298..3612540 Escherichia fergusonii ATCC 35469 7120820 YP_002384608.1 CDS ldrD NC_011740.1 3612429 3612536 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12123448; Product type f : factor; toxic polypeptide, small complement(3612429..3612536) Escherichia fergusonii ATCC 35469 7120281 YP_002384609.1 CDS EFER_3533 NC_011740.1 3612957 3614168 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15901718; Product type e : enzyme; methionine gamma-lyase 3612957..3614168 Escherichia fergusonii ATCC 35469 7122357 YP_002384610.1 CDS EFER_3534 NC_011740.1 3614172 3614396 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3614172..3614396) Escherichia fergusonii ATCC 35469 7120282 YP_002384611.1 CDS yhjV NC_011740.1 3614418 3615716 D Evidence 2b : Function of strongly homologous gene; PubMedId : 15901718; Product type t : transporter; transporter 3614418..3615716 Escherichia fergusonii ATCC 35469 7120283 YP_002384612.1 CDS EFER_3536 NC_011740.1 3615732 3617063 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1779763; Product type pr : regulator; transcriptional regulator complement(3615732..3617063) Escherichia fergusonii ATCC 35469 7124055 YP_002384613.1 CDS dppF NC_011740.1 3617106 3618110 R Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides; dipeptide transporter ATP-binding subunit complement(3617106..3618110) Escherichia fergusonii ATCC 35469 7123132 YP_002384614.1 CDS dppD NC_011740.1 3618107 3619090 R DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF; dipeptide transporter ATP-binding subunit complement(3618107..3619090) Escherichia fergusonii ATCC 35469 7122919 YP_002384615.1 CDS dppC NC_011740.1 3619101 3620003 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 7536291; Product type t : transporter; dipeptide transporter complement(3619101..3620003) Escherichia fergusonii ATCC 35469 7122918 YP_002384616.1 CDS dppB NC_011740.1 3620013 3621032 R transports peptides consisting of two or three amino acids; dipeptide transporter permease DppB complement(3620013..3621032) Escherichia fergusonii ATCC 35469 7123554 YP_002384617.1 CDS dppA NC_011740.1 3621183 3622790 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91100289, 92065799, 1702779, 1956284, 7536291, 8527431, 8563629, 9298646, 9600841, 9740056, 10972807; Product type t : transporter; dipeptide ABC transporter substrate-binding protein complement(3621183..3622790) Escherichia fergusonii ATCC 35469 7122917 YP_002384618.1 CDS yhjW NC_011740.1 3623827 3625683 R catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide; phosphoethanolamine transferase complement(3623827..3625683) Escherichia fergusonii ATCC 35469 7123637 YP_002384619.1 CDS yhjX NC_011740.1 3625867 3627222 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter complement(3625867..3627222) Escherichia fergusonii ATCC 35469 7122525 YP_002384620.1 CDS yhjY NC_011740.1 3627296 3628039 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8449874; Product type pe : enzyme; lipase complement(3627296..3628039) Escherichia fergusonii ATCC 35469 7122526 YP_002384621.1 CDS tag NC_011740.1 3628033 3628719 D constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine; 3-methyladenine DNA glycosylase 3628033..3628719 Escherichia fergusonii ATCC 35469 7122527 YP_002384622.1 CDS yiaC NC_011740.1 3628604 3629149 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2180922; Product type pe : enzyme; hypothetical protein 3628604..3629149 Escherichia fergusonii ATCC 35469 7121971 YP_002384623.1 CDS bisC NC_011740.1 3629118 3631397 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 82119950, 90202748, 2180922, 374979; Product type e : enzyme; biotin sulfoxide reductase complement(3629118..3631397) Escherichia fergusonii ATCC 35469 7122529 YP_002384624.1 CDS yiaD NC_011740.1 3631604 3632263 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; outer membrane lipoprotein 3631604..3632263 Escherichia fergusonii ATCC 35469 7123905 YP_002384625.1 CDS EFER_3550 NC_011740.1 3632309 3633385 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1639817; Product type pr : regulator; LacI family transcriptional regulator 3632309..3633385 Escherichia fergusonii ATCC 35469 7122530 YP_002384626.1 CDS EFER_3551 NC_011740.1 3633485 3634234 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10931350; Product type pe : enzyme; sugar or sugar phosphate isomerase 3633485..3634234 Escherichia fergusonii ATCC 35469 7120284 YP_002384627.1 CDS EFER_3552 NC_011740.1 3634209 3635177 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; 2-dehydro-3-deoxygluconokinase 3634209..3635177 Escherichia fergusonii ATCC 35469 7120285 YP_002384628.1 CDS EFER_3553 NC_011740.1 3635272 3636552 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7592429; Product type pt : transporter; carboxylate-containing product, possibly ketogluconate transporter 3635272..3636552 Escherichia fergusonii ATCC 35469 7120286 YP_002384629.1 CDS tiaE NC_011740.1 3636574 3637548 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15801772, 11237876, 99030322, 99357626, 9298646, 9811658; Product type e : enzyme; 2-oxo-carboxylic acid reductase 3636574..3637548 Escherichia fergusonii ATCC 35469 7120287 YP_002384630.1 CDS yiaF NC_011740.1 3637641 3638411 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3637641..3638411) Escherichia fergusonii ATCC 35469 7122131 YP_002384631.1 CDS EFER_3556 NC_011740.1 3638759 3640159 D Evidence 2b : Function of strongly homologous gene; PubMedId : 7961399; Product type t : transporter; aromatic acid transporter 3638759..3640159 Escherichia fergusonii ATCC 35469 7122531 YP_002384632.1 CDS yiaG NC_011740.1 3640409 3640699 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator 3640409..3640699 Escherichia fergusonii ATCC 35469 7123133 YP_002384633.1 CDS cspA NC_011740.1 3640981 3641193 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20345064, 90115858, 94293754, 94293756, 99177178, 10696873, 1597410, 1961761, 2404279, 7515185, 8197194, 9405743, 9439003, 9692981; Product type f : factor; major cold shock protein 3640981..3641193 Escherichia fergusonii ATCC 35469 7123493 YP_002384634.1 CDS EFER_3559 NC_011740.1 3641247 3641618 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3641247..3641618) Escherichia fergusonii ATCC 35469 7122817 YP_002384635.1 CDS glyS NC_011740.1 3642252 3644321 R glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta complement(3642252..3644321) Escherichia fergusonii ATCC 35469 7120288 YP_002384636.1 CDS glyQ NC_011740.1 3644331 3645242 R glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha complement(3644331..3645242) Escherichia fergusonii ATCC 35469 7120592 YP_002384637.1 CDS ysaB NC_011740.1 3645338 3645640 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3645338..3645640) Escherichia fergusonii ATCC 35469 7120591 YP_002384638.1 CDS yiaH NC_011740.1 3645809 3646804 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 3645809..3646804 Escherichia fergusonii ATCC 35469 7119756 YP_002384639.1 CDS yiaB NC_011740.1 3646869 3647252 R Evidence 2b : Function of strongly homologous gene; PubMedId : 15919996; Product type m : membrane component; hypothetical protein complement(3646869..3647252) Escherichia fergusonii ATCC 35469 7123494 YP_002384640.1 CDS xylB NC_011740.1 3647383 3648846 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6330500, 92366447, 95050816, 6320721; Product type e : enzyme; xylulokinase complement(3647383..3648846) Escherichia fergusonii ATCC 35469 7122528 YP_002384641.1 CDS xylA NC_011740.1 3648910 3650232 R catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase complement(3648910..3650232) Escherichia fergusonii ATCC 35469 7122389 YP_002384642.1 CDS xylR NC_011740.1 3650444 3651718 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 6330500, 94316500; Product type r : regulator; DNA-binding transcriptional activator 3650444..3651718 Escherichia fergusonii ATCC 35469 7122388 YP_002384643.1 CDS bax NC_011740.1 3651772 3652596 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 1544897; hypothetical protein complement(3651772..3652596) Escherichia fergusonii ATCC 35469 7122391 YP_002384644.1 CDS malS NC_011740.1 3652839 3654947 D periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds; periplasmic alpha-amylase 3652839..3654947 Escherichia fergusonii ATCC 35469 7121646 YP_002384645.1 CDS avtA NC_011740.1 3655123 3656376 D transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis; valine--pyruvate transaminase 3655123..3656376 Escherichia fergusonii ATCC 35469 7121226 YP_002384646.1 CDS yiaI NC_011740.1 3656413 3657006 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; hydrogenase, 4Fe-4S ferredoxin-type component complement(3656413..3657006) Escherichia fergusonii ATCC 35469 7123901 YP_002384647.1 CDS yiaJ NC_011740.1 3657003 3657875 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 20372646, 9826648; Product type r : regulator; DNA-binding transcriptional repressor complement(3657003..3657875) Escherichia fergusonii ATCC 35469 7122532 YP_002384648.1 CDS yiaK NC_011740.1 3658035 3659033 D NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate; 2,3-diketo-L-gulonate reductase 3658035..3659033 Escherichia fergusonii ATCC 35469 7122533 YP_002384649.1 CDS yiaL NC_011740.1 3659045 3659512 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 21617392; hypothetical protein 3659045..3659512 Escherichia fergusonii ATCC 35469 7122534 YP_002384650.1 CDS yiaM NC_011740.1 3659630 3660103 D membrane-spanning protein involved in uptake of 2,3-diketo-L-gulonate; part of the tri-partite ATP-independent periplasmic transport system (TRAP) YiaMNO; 2,3-diketo-L-gulonate TRAP transporter small permease YiaM 3659630..3660103 Escherichia fergusonii ATCC 35469 7122535 YP_002384651.1 CDS yiaN NC_011740.1 3660106 3661383 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14668138, 21617392; Product type t : transporter; transporter 3660106..3661383 Escherichia fergusonii ATCC 35469 7124056 YP_002384652.1 CDS yiaO NC_011740.1 3661396 3662382 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14668138, 21617392; Product type t : transporter; transporter 3661396..3662382 Escherichia fergusonii ATCC 35469 7124057 YP_002384653.1 CDS lyxK NC_011740.1 3662386 3663882 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21617392, 95050816, 7961955; Product type e : enzyme; L-xylulose kinase 3662386..3663882 Escherichia fergusonii ATCC 35469 7122536 YP_002384654.1 CDS sgbH NC_011740.1 3663879 3664541 D catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate; 3-keto-L-gulonate-6-phosphate decarboxylase 3663879..3664541 Escherichia fergusonii ATCC 35469 7121218 YP_002384655.1 CDS sgbU NC_011740.1 3664534 3665394 D L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate; L-xylulose 5-phosphate 3-epimerase 3664534..3665394 Escherichia fergusonii ATCC 35469 7123921 YP_002384656.1 CDS sgbE NC_011740.1 3665388 3666083 D catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 3665388..3666083 Escherichia fergusonii ATCC 35469 7121778 YP_002384657.1 CDS aldB NC_011740.1 3666130 3667668 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95286498, 7768815; Product type e : enzyme; aldehyde dehydrogenase B complement(3666130..3667668) Escherichia fergusonii ATCC 35469 7121777 YP_002384658.1 CDS yiaY NC_011740.1 3667869 3669020 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2935393; Product type e : enzyme; alcohol dehydrogenase complement(3667869..3669020) Escherichia fergusonii ATCC 35469 7122292 YP_002384659.1 CDS selB NC_011740.1 3669210 3671057 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90264431, 91317715, 9315303, 94148228, 2140572, 2531290; Product type f : factor; selenocysteinyl-tRNA-specific translation factor complement(3669210..3671057) Escherichia fergusonii ATCC 35469 7122537 YP_002384660.1 CDS selA NC_011740.1 3671054 3672445 R catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis; selenocysteine synthase complement(3671054..3672445) Escherichia fergusonii ATCC 35469 7121767 YP_002384661.1 CDS yibF NC_011740.1 3672543 3673151 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8624414; Product type pe : enzyme; glutathione S-transferase complement(3672543..3673151) Escherichia fergusonii ATCC 35469 7121766 YP_002384662.1 CDS yibH NC_011740.1 3673220 3674356 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3673220..3674356) Escherichia fergusonii ATCC 35469 7124058 YP_002384663.1 CDS yibI NC_011740.1 3674359 3674721 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(3674359..3674721) Escherichia fergusonii ATCC 35469 7122539 YP_002384664.1 CDS EFER_3589 NC_011740.1 3674919 3675200 D Evidence 6 : Doubtful CDS; hypothetical protein 3674919..3675200 Escherichia fergusonii ATCC 35469 7122540 YP_002384665.1 CDS mtlA NC_011740.1 3675257 3677173 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92052139, 92283796, 94131964, 1946374, 3135464, 3142516, 6309813, 9551558; Product type t : transporter; PTS system mannitol-specific transporter subunit IIABC 3675257..3677173 Escherichia fergusonii ATCC 35469 7120289 YP_002384666.1 CDS mtlD NC_011740.1 3677268 3678416 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90254197, 1964486, 3135464, 6384188, 8300537, 13295236; Product type e : enzyme; mannitol-1-phosphate 5-dehydrogenase 3677268..3678416 Escherichia fergusonii ATCC 35469 7120638 YP_002384667.1 CDS mtlR NC_011740.1 3678459 3679004 D Acts as a repressor of the mtlAD operon; mannitol repressor protein 3678459..3679004 Escherichia fergusonii ATCC 35469 7120639 YP_002384668.1 CDS EFER_3593 NC_011740.1 3679017 3679301 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3679017..3679301) Escherichia fergusonii ATCC 35469 7120640 YP_002384669.1 CDS yibL NC_011740.1 3679512 3679874 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3679512..3679874 Escherichia fergusonii ATCC 35469 7120290 YP_002384670.1 CDS EFER_3595 NC_011740.1 3680406 3681080 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; lipoprotein 3680406..3681080 Escherichia fergusonii ATCC 35469 7122542 YP_002384671.1 CDS EFER_3596 NC_011740.1 3681110 3686497 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2117568; Product type pm : membrane component; protein; outer membrane protein 3681110..3686497 Escherichia fergusonii ATCC 35469 7123134 YP_002384672.1 CDS lldP NC_011740.1 3686925 3688580 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94012541, 11283302, 11785976, 8407843; Product type t : transporter; L-lactate permease 3686925..3688580 Escherichia fergusonii ATCC 35469 7120291 YP_002384673.1 CDS lldR NC_011740.1 3688580 3689356 D represses the lctPRD operon; DNA-binding transcriptional repressor LldR 3688580..3689356 Escherichia fergusonii ATCC 35469 7120842 YP_002384674.1 CDS lldD NC_011740.1 3689353 3690543 D flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; L-lactate dehydrogenase 3689353..3690543 Escherichia fergusonii ATCC 35469 7120843 YP_002384675.1 CDS yibK NC_011740.1 3690591 3691064 D member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates; tRNA/rRNA methyltransferase YibK 3690591..3691064 Escherichia fergusonii ATCC 35469 7120841 YP_002384676.1 CDS cysE NC_011740.1 3691117 3691938 R catalyzes the O-acetylation of serine; serine acetyltransferase complement(3691117..3691938) Escherichia fergusonii ATCC 35469 7122541 YP_002384677.1 CDS gpsA NC_011740.1 3692018 3693037 R catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase complement(3692018..3693037) Escherichia fergusonii ATCC 35469 7122849 YP_002384678.1 CDS secB NC_011740.1 3693037 3693504 R molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be to SecA; preprotein translocase subunit SecB complement(3693037..3693504) Escherichia fergusonii ATCC 35469 7120612 YP_002384679.1 CDS grxC NC_011740.1 3693566 3693817 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94316500, 95024051, 99175138, 11031118, 7937896, 8636094, 9973569; Product type c : carrier; glutaredoxin 3 complement(3693566..3693817) Escherichia fergusonii ATCC 35469 7123372 YP_002384680.1 CDS yibN NC_011740.1 3693846 3694277 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; rhodanese-related sulfurtransferase complement(3693846..3694277) Escherichia fergusonii ATCC 35469 7120618 YP_002384681.1 CDS gpmI NC_011740.1 3694523 3696067 D catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 3694523..3696067 Escherichia fergusonii ATCC 35469 7122543 YP_002384682.1 CDS envC NC_011740.1 3696101 3697360 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12113939, 21972773; Product type cp : cell process; hypothetical protein 3696101..3697360 Escherichia fergusonii ATCC 35469 7120610 YP_002384683.1 CDS yibQ NC_011740.1 3697364 3698320 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; polysaccharide deacetylase 3697364..3698320 Escherichia fergusonii ATCC 35469 7124134 YP_002384684.1 CDS yibD NC_011740.1 3698307 3699341 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15659689, 2647748; Product type pe : enzyme; glycosyl transferase family protein complement(3698307..3699341) Escherichia fergusonii ATCC 35469 7122544 YP_002384685.1 CDS hemN NC_011740.1 3699666 3701039 R catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase complement(3699666..3701039) Escherichia fergusonii ATCC 35469 7122538 YP_002384686.1 CDS yihI NC_011740.1 3701228 3701797 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3701228..3701797) Escherichia fergusonii ATCC 35469 7122185 YP_002384687.1 CDS engB NC_011740.1 3702355 3702951 D binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 3702355..3702951 Escherichia fergusonii ATCC 35469 7122824 YP_002384688.1 CDS polA NC_011740.1 3703302 3706088 R has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I complement(3703302..3706088) Escherichia fergusonii ATCC 35469 7121808 YP_002384689.1 CDS yihG NC_011740.1 3706427 3707380 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; acyltransferase 3706427..3707380 Escherichia fergusonii ATCC 35469 7120097 YP_002384690.1 CDS EFER_3615 NC_011740.1 3707425 3708843 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3707425..3708843) Escherichia fergusonii ATCC 35469 7123386 YP_002384691.1 CDS dsbA NC_011740.1 3709008 3709634 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12498799, 93264419, 94016574, 94206930, 99298180, 10210188, 1429594, 1740115, 1934062, 8413591, 8494885, 8521518, 9194175, 9298646, 9300489, 9572841, 9600841, 9655827; Product type e : enzyme; protein disulfide isomerase I complement(3709008..3709634) Escherichia fergusonii ATCC 35469 7120292 YP_002384692.1 CDS yihE NC_011740.1 3709651 3710637 R catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages; serine/threonine protein kinase complement(3709651..3710637) Escherichia fergusonii ATCC 35469 7123555 YP_002384693.1 CDS yihD NC_011740.1 3710714 3710983 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3710714..3710983) Escherichia fergusonii ATCC 35469 7123934 YP_002384694.1 CDS mobA NC_011740.1 3711062 3711637 D in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; molybdopterin-guanine dinucleotide biosynthesis protein MobA 3711062..3711637 Escherichia fergusonii ATCC 35469 7121848 YP_002384695.1 CDS mobB NC_011740.1 3711634 3712146 D in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway; molybdopterin-guanine dinucleotide biosynthesis protein MobB 3711634..3712146 Escherichia fergusonii ATCC 35469 7123247 YP_002384696.1 CDS hemG NC_011740.1 3717735 3718280 R catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX; protoporphyrinogen oxidase complement(3717735..3718280) Escherichia fergusonii ATCC 35469 7120385 YP_002384697.1 CDS trkH NC_011740.1 3718292 3719743 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91100357, 2243799, 7896723; Product type t : transporter; potassium transporter complement(3718292..3719743) Escherichia fergusonii ATCC 35469 7122183 YP_002384698.1 CDS yigZ NC_011740.1 3719782 3720396 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15103642; Product type pf : factor; hypothetical protein complement(3719782..3720396) Escherichia fergusonii ATCC 35469 7122158 YP_002384699.1 CDS pepQ NC_011740.1 3720396 3721727 R catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters; proline dipeptidase complement(3720396..3721727) Escherichia fergusonii ATCC 35469 7121846 YP_002384700.1 CDS fadB NC_011740.1 3721917 3724106 D includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; multifunctional fatty acid oxidation complex subunit alpha 3721917..3724106 Escherichia fergusonii ATCC 35469 7122578 YP_002384701.1 CDS fadA NC_011740.1 3724116 3725279 D FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids; 3-ketoacyl-CoA thiolase 3724116..3725279 Escherichia fergusonii ATCC 35469 7119986 YP_002384702.1 CDS EFER_3637 NC_011740.1 3725463 3727298 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; arylsulfatase complement(3725463..3727298) Escherichia fergusonii ATCC 35469 7119985 YP_002384703.1 CDS fre NC_011740.1 3727568 3728269 R NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin; FMN reductase complement(3727568..3728269) Escherichia fergusonii ATCC 35469 7120293 YP_002384704.1 CDS ubiD NC_011740.1 3728315 3729808 R catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase complement(3728315..3729808) Escherichia fergusonii ATCC 35469 7123012 YP_002384705.1 CDS rfaH NC_011740.1 3729975 3730463 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92011415, 92250420, 92261317, 1584020, 12007406; Product type r : regulator; transcriptional activator RfaH 3729975..3730463 Escherichia fergusonii ATCC 35469 7122618 YP_002384706.1 CDS tatD NC_011740.1 3730460 3731242 R magnesium dependent; not involved in the Sec-independent protein export system; DNase TatD complement(3730460..3731242) Escherichia fergusonii ATCC 35469 7121387 YP_002384707.1 CDS tatC NC_011740.1 3731284 3732057 R with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane; twin-arginine protein translocation system subunit TatC complement(3731284..3732057) Escherichia fergusonii ATCC 35469 7121977 YP_002384708.1 CDS tatB NC_011740.1 3732060 3732584 R mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase complement(3732060..3732584) Escherichia fergusonii ATCC 35469 7121976 YP_002384709.1 CDS tatA NC_011740.1 3732588 3732857 R TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin arginine translocase protein A complement(3732588..3732857) Escherichia fergusonii ATCC 35469 7121975 YP_002384710.1 CDS ubiB NC_011740.1 3732936 3734576 R an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; ubiquinone biosynthesis protein UbiB complement(3732936..3734576) Escherichia fergusonii ATCC 35469 7121974 YP_002384711.1 CDS yigP NC_011740.1 3734573 3735178 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3734573..3735178) Escherichia fergusonii ATCC 35469 7122616 YP_002384712.1 CDS ubiE NC_011740.1 3735192 3735947 R Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase complement(3735192..3735947) Escherichia fergusonii ATCC 35469 7121845 YP_002384713.1 CDS rmuC NC_011740.1 3736042 3737469 R YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner; DNA recombination protein RmuC complement(3736042..3737469) Escherichia fergusonii ATCC 35469 7122619 YP_002384714.1 CDS EFER_3649 NC_011740.1 3737685 3738452 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator 3737685..3738452 Escherichia fergusonii ATCC 35469 7121420 YP_002384715.1 CDS EFER_3650 NC_011740.1 3738476 3739480 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; acidic carbohydrate kinase 3738476..3739480 Escherichia fergusonii ATCC 35469 7120294 YP_002384716.1 CDS EFER_3651 NC_011740.1 3739395 3740099 D catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase 3739395..3740099 Escherichia fergusonii ATCC 35469 7123674 YP_002384717.1 CDS EFER_3652 NC_011740.1 3740124 3741098 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; periplasmic binding protein 3740124..3741098 Escherichia fergusonii ATCC 35469 7120295 YP_002384718.1 CDS EFER_3653 NC_011740.1 3741115 3741621 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; permease subunit 3741115..3741621 Escherichia fergusonii ATCC 35469 7120296 YP_002384719.1 CDS EFER_3654 NC_011740.1 3741634 3743124 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3741634..3743124 Escherichia fergusonii ATCC 35469 7123675 YP_002384720.1 CDS udp NC_011740.1 3743159 3743929 R catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway; uridine phosphorylase complement(3743159..3743929) Escherichia fergusonii ATCC 35469 7120297 YP_002384721.1 CDS ysgA NC_011740.1 3744119 3744997 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12676709; Product type pe : enzyme; hydrolase 3744119..3744997 Escherichia fergusonii ATCC 35469 7122623 YP_002384722.1 CDS EFER_3657 NC_011740.1 3745084 3745848 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7805834; Product type pr : regulator; GntR family transcriptional regulator complement(3745084..3745848) Escherichia fergusonii ATCC 35469 7119757 YP_002384723.1 CDS EFER_3658 NC_011740.1 3745939 3746757 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hydrolase 3745939..3746757 Escherichia fergusonii ATCC 35469 7123135 YP_002384724.1 CDS EFER_3659 NC_011740.1 3746930 3747805 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3746930..3747805 Escherichia fergusonii ATCC 35469 7120298 YP_002384725.1 CDS EFER_3660 NC_011740.1 3747778 3748230 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3747778..3748230 Escherichia fergusonii ATCC 35469 7120299 YP_002384726.1 CDS EFER_3661 NC_011740.1 3748290 3748967 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; extracellular solute-binding protein complement(3748290..3748967) Escherichia fergusonii ATCC 35469 7120300 YP_002384727.1 CDS EFER_3662 NC_011740.1 3748970 3749938 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; HTH-type transcriptional regulator complement(3748970..3749938) Escherichia fergusonii ATCC 35469 7120301 YP_002384728.1 CDS EFER_3663 NC_011740.1 3750409 3751467 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; lactonase 3750409..3751467 Escherichia fergusonii ATCC 35469 7123136 YP_002384729.1 CDS EFER_3664 NC_011740.1 3751479 3752744 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3751479..3752744 Escherichia fergusonii ATCC 35469 7120302 YP_002384730.1 CDS EFER_3665 NC_011740.1 3752769 3754715 D Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 3752769..3754715 Escherichia fergusonii ATCC 35469 7120303 YP_002384731.1 CDS EFER_3666 NC_011740.1 3754760 3755929 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3754760..3755929 Escherichia fergusonii ATCC 35469 7120304 YP_002384732.1 CDS EFER_3667 NC_011740.1 3755968 3758232 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3755968..3758232 Escherichia fergusonii ATCC 35469 7120305 YP_002384733.1 CDS EFER_3668 NC_011740.1 3758247 3759410 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; Isocitrate dehydrogenase 3758247..3759410 Escherichia fergusonii ATCC 35469 7123137 YP_002384734.1 CDS EFER_3669 NC_011740.1 3759467 3761989 D catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase 3759467..3761989 Escherichia fergusonii ATCC 35469 7120306 YP_002384735.1 CDS EFER_3670 NC_011740.1 3762227 3763081 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; fumarylacetoacetate (FAA) hydrolase 3762227..3763081 Escherichia fergusonii ATCC 35469 7120307 YP_002384736.1 CDS metE NC_011740.1 3763116 3765377 R catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase complement(3763116..3765377) Escherichia fergusonii ATCC 35469 7120308 YP_002384737.1 CDS metR NC_011740.1 3765495 3766448 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90384950, 96303520, 2205852, 2643109; Product type r : regulator; DNA-binding transcriptional activator 3765495..3766448 Escherichia fergusonii ATCC 35469 7120917 YP_002384738.1 CDS yigM NC_011740.1 3766336 3767235 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(3766336..3767235) Escherichia fergusonii ATCC 35469 7120926 YP_002384739.1 CDS yigL NC_011740.1 3767311 3768111 R purine and pyrimidine nucleotides are secondary substrates; yigL expression is regulated by heat shock, osmotic shock and starvation of glucose, phosphate or ammonium; sugar phosphatase complement(3767311..3768111) Escherichia fergusonii ATCC 35469 7121844 YP_002384740.1 CDS pldB NC_011740.1 3768119 3769141 R lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates; lysophospholipase L2 complement(3768119..3769141) Escherichia fergusonii ATCC 35469 7123385 YP_002384741.1 CDS rhtB NC_011740.1 3769252 3769872 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99313167, 10386596; Product type t : transporter; homoserine/homoserine lactone efflux protein 3769252..3769872 Escherichia fergusonii ATCC 35469 7123641 YP_002384742.1 CDS EFER_3677 NC_011740.1 3770031 3770891 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3770031..3770891 Escherichia fergusonii ATCC 35469 7121403 YP_002384743.1 CDS rhtC NC_011740.1 3770928 3771548 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 99313167, 10386596, 3027506; Product type t : transporter; threonine efflux system complement(3770928..3771548) Escherichia fergusonii ATCC 35469 7120309 YP_002384744.1 CDS recQ NC_011740.1 3771612 3773441 R functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; ATP-dependent DNA helicase RecQ complement(3771612..3773441) Escherichia fergusonii ATCC 35469 7121404 YP_002384745.1 CDS EFER_3680 NC_011740.1 3773511 3773993 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3773511..3773993) Escherichia fergusonii ATCC 35469 7123310 YP_002384746.1 CDS pldA NC_011740.1 3774042 3774911 R catalyzes the hydrolysis of phosphatidylcholine; phospholipase A complement(3774042..3774911) Escherichia fergusonii ATCC 35469 7123676 YP_002384747.1 CDS yigI NC_011740.1 3775075 3775542 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3775075..3775542 Escherichia fergusonii ATCC 35469 7120087 YP_002384748.1 CDS rarD NC_011740.1 3775594 3776484 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; chloramphenicol resistance permease 3775594..3776484 Escherichia fergusonii ATCC 35469 7121843 YP_002384749.1 CDS EFER_3684 NC_011740.1 3776649 3776765 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3776649..3776765) Escherichia fergusonii ATCC 35469 7123466 YP_002384750.1 CDS yigF NC_011740.1 3776974 3777354 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9868784; Product type pm : membrane component; hypothetical protein 3776974..3777354 Escherichia fergusonii ATCC 35469 7120310 YP_002384751.1 CDS corA NC_011740.1 3777397 3778347 R responsible for the influx of magnesium ions; magnesium/nickel/cobalt transporter CorA complement(3777397..3778347) Escherichia fergusonii ATCC 35469 7121842 YP_002384752.1 CDS yigE NC_011740.1 3778717 3779481 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3778717..3779481 Escherichia fergusonii ATCC 35469 7122794 YP_002384753.1 CDS EFER_3688 NC_011740.1 3779564 3780466 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3779564..3780466 Escherichia fergusonii ATCC 35469 7121841 YP_002384754.1 CDS uvrD NC_011740.1 3780521 3782683 R unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair.; DNA-dependent helicase II complement(3780521..3782683) Escherichia fergusonii ATCC 35469 7120311 YP_002384755.1 CDS yigB NC_011740.1 3782767 3783483 R YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function; flavin mononucleotide phosphatase complement(3782767..3783483) Escherichia fergusonii ATCC 35469 7122648 YP_002384756.1 CDS xerC NC_011740.1 3783483 3784379 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC complement(3783483..3784379) Escherichia fergusonii ATCC 35469 7121840 YP_002384757.1 CDS yigA NC_011740.1 3784376 3785083 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3784376..3785083) Escherichia fergusonii ATCC 35469 7122384 YP_002384758.1 CDS dapF NC_011740.1 3785080 3785904 R involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase complement(3785080..3785904) Escherichia fergusonii ATCC 35469 7123384 YP_002384759.1 CDS yifL NC_011740.1 3785941 3786144 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; lipoprotein complement(3785941..3786144) Escherichia fergusonii ATCC 35469 7122868 YP_002384760.1 CDS EFER_3695 NC_011740.1 3786303 3787811 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3786303..3787811 Escherichia fergusonii ATCC 35469 7121839 YP_002384761.1 CDS EFER_3696 NC_011740.1 3787808 3789121 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3787808..3789121 Escherichia fergusonii ATCC 35469 7123677 YP_002384762.1 CDS cyaY NC_011740.1 3789184 3789504 D defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly; frataxin-like protein 3789184..3789504 Escherichia fergusonii ATCC 35469 7123678 YP_002384763.1 CDS cyaA NC_011740.1 3789544 3792090 R catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP; adenylate cyclase complement(3789544..3792090) Escherichia fergusonii ATCC 35469 7123540 YP_002384764.1 CDS hemC NC_011740.1 3792455 3793396 D transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 3792455..3793396 Escherichia fergusonii ATCC 35469 7122836 YP_002384765.1 CDS hemD NC_011740.1 3793393 3794133 D catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; uroporphyrinogen-III synthase 3793393..3794133 Escherichia fergusonii ATCC 35469 7123728 YP_002384766.1 CDS hemX NC_011740.1 3794155 3795330 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 89098348, 92358234, 3054815, 3062586, 9298646; Product type pe : enzyme; uroporphyrinogen III C-methyltransferase 3794155..3795330 Escherichia fergusonii ATCC 35469 7123573 YP_002384767.1 CDS hemY NC_011740.1 3795333 3796529 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 89041586; Product type pe : enzyme; protoheme IX biogenesis protein 3795333..3796529 Escherichia fergusonii ATCC 35469 7122186 YP_002384768.1 CDS EFER_3704 NC_011740.1 3796322 3797167 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 3796322..3797167 Escherichia fergusonii ATCC 35469 7123996 YP_002384769.1 CDS aslA NC_011740.1 3797815 3799470 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 16766528, 92358234, 15477040; Product type e : enzyme; arylsulfatase-like protein 3797815..3799470 Escherichia fergusonii ATCC 35469 7121184 YP_002384770.1 CDS aslB NC_011740.1 3799561 3800796 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11222759, 2180918, 12419807, 14749327; Product type pr : regulator; regulator of arylsulfatase activity complement(3799561..3800796) Escherichia fergusonii ATCC 35469 7120564 YP_002384771.1 CDS yifK NC_011740.1 3801483 3802868 R uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function; transporter complement(3801483..3802868) Escherichia fergusonii ATCC 35469 7123095 YP_002384772.1 CDS rffM NC_011740.1 3803059 3803799 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88086874, 90337949, 92112804; Product type e : enzyme; UDP-N-acetyl-D-mannosaminuronic acid transferase complement(3803059..3803799) Escherichia fergusonii ATCC 35469 7123933 YP_002384773.1 CDS wzyE NC_011740.1 3803802 3805154 R enterobacterial common antigen polymerase; common antigen polymerase complement(3803802..3805154) Escherichia fergusonii ATCC 35469 7123860 YP_002384774.1 CDS rffT NC_011740.1 3805151 3806230 R catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis; 4-alpha-L-fucosyltransferase complement(3805151..3806230) Escherichia fergusonii ATCC 35469 7122378 YP_002384775.1 CDS wzxE NC_011740.1 3806227 3807477 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12621029, 20044778; Product type t : transporter; O-antigen translocase complement(3806227..3807477) Escherichia fergusonii ATCC 35469 7121395 YP_002384776.1 CDS rffA NC_011740.1 3807479 3808609 R catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis; TDP-4-oxo-6-deoxy-D-glucose transaminase complement(3807479..3808609) Escherichia fergusonii ATCC 35469 7122377 YP_002384777.1 CDS rffC NC_011740.1 3808614 3809288 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90212314, 90337949, 92112804, 8366065; Product type e : enzyme; TDP-fucosamine acetyltransferase complement(3808614..3809288) Escherichia fergusonii ATCC 35469 7123312 YP_002384778.1 CDS rffH NC_011740.1 3809266 3810147 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94292435, 96032389; Product type e : enzyme; glucose-1-phosphate thymidylyltransferase complement(3809266..3810147) Escherichia fergusonii ATCC 35469 7121391 YP_002384779.1 CDS rffG NC_011740.1 3810166 3811233 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 88086930, 90212314, 90337949, 92112804, 92174908, 94018634, 94042873, 7559340; Product type e : enzyme; dTDP-glucose 4,6-dehydratase complement(3810166..3811233) Escherichia fergusonii ATCC 35469 7123313 YP_002384780.1 CDS wecC NC_011740.1 3811233 3812495 R catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid; UDP-N-acetyl-D-mannosamine dehydrogenase complement(3811233..3812495) Escherichia fergusonii ATCC 35469 7121394 YP_002384781.1 CDS rffE NC_011740.1 3812492 3813622 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90212314, 90337949, 92112804, 94042873, 11106477, 7559340, 8170390, 8226648; Product type e : enzyme; UDP-N-acetyl glucosamine-2-epimerase complement(3812492..3813622) Escherichia fergusonii ATCC 35469 7121392 YP_002384782.1 CDS wzzE NC_011740.1 3813678 3814724 R Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein; lipopolysaccharide biosynthesis protein WzzE complement(3813678..3814724) Escherichia fergusonii ATCC 35469 7121393 YP_002384783.1 CDS rfe NC_011740.1 3814736 3815839 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92114763, 94245613, 94292435, 10629198, 11024259, 11700352, 11832520, 1722555, 1730666; Product type e : enzyme; UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase complement(3814736..3815839) Escherichia fergusonii ATCC 35469 7122379 YP_002384784.1 CDS rho NC_011740.1 3816067 3817326 R An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho complement(3816067..3817326) Escherichia fergusonii ATCC 35469 7121390 YP_002384785.1 CDS trxA NC_011740.1 3817651 3817980 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90202710, 91154193, 92250497, 99175138, 10489448, 1094461, 10947986, 1561103, 2181145, 2193685, 3891733, 4616096, 4883076, 6098320, 6099324, 7812718, 8098620, 8253691; Product type c : carrier; thioredoxin complement(3817651..3817980) Escherichia fergusonii ATCC 35469 7121401 YP_002384786.1 CDS rhlB NC_011740.1 3818111 3819376 D enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation; ATP-dependent RNA helicase RhlB 3818111..3819376 Escherichia fergusonii ATCC 35469 7123438 YP_002384787.1 CDS gpp NC_011740.1 3819512 3820996 D catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation; guanosine pentaphosphate phosphohydrolase 3819512..3820996 Escherichia fergusonii ATCC 35469 7121400 YP_002384788.1 CDS rep NC_011740.1 3821044 3823065 R single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication; ATP-dependent DNA helicase Rep complement(3821044..3823065) Escherichia fergusonii ATCC 35469 7120611 YP_002384789.1 CDS ppiC NC_011740.1 3823152 3823433 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94215709, 7878732, 7925971, 8163020; Product type e : enzyme; peptidyl-prolyl cis-trans isomerase C 3823152..3823433 Escherichia fergusonii ATCC 35469 7121386 YP_002384790.1 CDS ilvC NC_011740.1 3823479 3824954 R catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase complement(3823479..3824954) Escherichia fergusonii ATCC 35469 7123107 YP_002384791.1 CDS ilvY NC_011740.1 3825020 3825994 D participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate; DNA-binding transcriptional regulator IlvY 3825020..3825994 Escherichia fergusonii ATCC 35469 7120728 YP_002384792.1 CDS ilvA NC_011740.1 3825991 3827535 R threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway; threonine dehydratase complement(3825991..3827535) Escherichia fergusonii ATCC 35469 7123211 YP_002384793.1 CDS ilvD NC_011740.1 3827538 3829388 R catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase complement(3827538..3829388) Escherichia fergusonii ATCC 35469 7120726 YP_002384794.1 CDS ilvE NC_011740.1 3829453 3830382 R catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase complement(3829453..3830382) Escherichia fergusonii ATCC 35469 7120729 YP_002384795.1 CDS ilvM NC_011740.1 3830402 3830665 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92332418, 92380929, 1569580, 3550695, 3897211; Product type e : enzyme; acetolactate synthase 2 regulatory subunit complement(3830402..3830665) Escherichia fergusonii ATCC 35469 7120730 YP_002384796.1 CDS ilvG NC_011740.1 3830662 3832308 R catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase 2 catalytic subunit complement(3830662..3832308) Escherichia fergusonii ATCC 35469 7120734 YP_002384797.1 CDS ilvL NC_011740.1 3832449 3832547 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87174741; Product type l : leader peptide; ilvG operon leader peptide complement(3832449..3832547) Escherichia fergusonii ATCC 35469 7120731 YP_002384798.1 CDS yifB NC_011740.1 3832870 3834420 D among the AAA+ ATPases, the YifB protease family belongs to the Helix 2 insert clade; unknown function; ATP-dependent protease 3832870..3834420 Escherichia fergusonii ATCC 35469 7120733 YP_002384799.1 CDS yifE NC_011740.1 3834445 3834783 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3834445..3834783) Escherichia fergusonii ATCC 35469 7121838 YP_002384800.1 CDS hdfR NC_011740.1 3834902 3835741 D Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon; transcriptional regulator HdfR 3834902..3835741 Escherichia fergusonii ATCC 35469 7123932 YP_002384801.1 CDS purH NC_011740.1 3841685 3843274 D involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 3841685..3843274 Escherichia fergusonii ATCC 35469 7120384 YP_002384802.1 CDS purD NC_011740.1 3843286 3844575 D catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 3843286..3844575 Escherichia fergusonii ATCC 35469 7124022 YP_002384803.1 CDS zraR NC_011740.1 3844572 3845897 R DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein; transcriptional regulatory protein ZraR complement(3844572..3845897) Escherichia fergusonii ATCC 35469 7122320 YP_002384804.1 CDS zraS NC_011740.1 3845894 3847270 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21140164, 89327164, 92255260, 11243806, 2666400; Product type r : regulator; sensor protein ZraS complement(3845894..3847270) Escherichia fergusonii ATCC 35469 7121814 YP_002384805.1 CDS zraP NC_011740.1 3847508 3847933 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98362023, 9694902; Product type pf : factor; zinc resistance protein 3847508..3847933 Escherichia fergusonii ATCC 35469 7123420 YP_002384806.1 CDS yjaH NC_011740.1 3847935 3848630 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3847935..3848630) Escherichia fergusonii ATCC 35469 7122667 YP_002384807.1 CDS hupA NC_011740.1 3848643 3848915 R histone-like DNA-binding protein; transcriptional regulator HU subunit alpha complement(3848643..3848915) Escherichia fergusonii ATCC 35469 7123937 YP_002384808.1 CDS yjaG NC_011740.1 3849102 3849692 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3849102..3849692) Escherichia fergusonii ATCC 35469 7122234 YP_002384809.1 CDS nfi NC_011740.1 3849735 3850406 R Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures; endonuclease V complement(3849735..3850406) Escherichia fergusonii ATCC 35469 7121864 YP_002384810.1 CDS hemE NC_011740.1 3850416 3851480 R catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase complement(3850416..3851480) Escherichia fergusonii ATCC 35469 7120685 YP_002384811.1 CDS nudC NC_011740.1 3851520 3852293 R can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates; NADH pyrophosphatase complement(3851520..3852293) Escherichia fergusonii ATCC 35469 7122181 YP_002384812.1 CDS rsd NC_011740.1 3852388 3852864 D binds specifically to the major sigma factor sigma 70; active in stationary phase; anti-RNA polymerase sigma 70 factor 3852388..3852864 Escherichia fergusonii ATCC 35469 7119668 YP_002384813.1 CDS thiC NC_011740.1 3853097 3854992 D required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 3853097..3854992 Escherichia fergusonii ATCC 35469 7121144 YP_002384814.1 CDS thiE NC_011740.1 3854992 3855627 D catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate; thiamine-phosphate pyrophosphorylase 3854992..3855627 Escherichia fergusonii ATCC 35469 7121990 YP_002384815.1 CDS thiF NC_011740.1 3855620 3856375 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 8432721, 94089392, 98298179, 10082377, 9632726; Product type e : enzyme; thiamin (thiazole moiety) biosynthesis protein 3855620..3856375 Escherichia fergusonii ATCC 35469 7121992 YP_002384816.1 CDS thiS NC_011740.1 3856359 3856559 D with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate; sulfur carrier protein ThiS 3856359..3856559 Escherichia fergusonii ATCC 35469 7121993 YP_002384817.1 CDS thiG NC_011740.1 3856561 3857331 D functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 3856561..3857331 Escherichia fergusonii ATCC 35469 7121999 YP_002384818.1 CDS thiH NC_011740.1 3857328 3858461 D in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center; thiamine biosynthesis protein ThiH 3857328..3858461 Escherichia fergusonii ATCC 35469 7123408 YP_002384819.1 CDS rpoC NC_011740.1 3858703 3862926 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' complement(3858703..3862926) Escherichia fergusonii ATCC 35469 7123960 YP_002384820.1 CDS rpoB NC_011740.1 3863003 3867031 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta complement(3863003..3867031) Escherichia fergusonii ATCC 35469 7121121 YP_002384821.1 CDS rplL NC_011740.1 3867351 3867716 R present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 complement(3867351..3867716) Escherichia fergusonii ATCC 35469 7121120 YP_002384822.1 CDS rplJ NC_011740.1 3867783 3868280 R binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 complement(3867783..3868280) Escherichia fergusonii ATCC 35469 7121102 YP_002384823.1 CDS rplA NC_011740.1 3868693 3869397 R in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 complement(3868693..3869397) Escherichia fergusonii ATCC 35469 7121100 YP_002384824.1 CDS rplK NC_011740.1 3869401 3869829 R binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 complement(3869401..3869829) Escherichia fergusonii ATCC 35469 7121438 YP_002384825.1 CDS nusG NC_011740.1 3869988 3870533 R Modulates Rho-dependent transcription termination; transcription antitermination protein NusG complement(3869988..3870533) Escherichia fergusonii ATCC 35469 7121101 YP_002384826.1 CDS secE NC_011740.1 3870535 3870918 R forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE complement(3870535..3870918) Escherichia fergusonii ATCC 35469 7119686 YP_002384827.1 CDS tufB NC_011740.1 3871148 3872332 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(3871148..3872332) Escherichia fergusonii ATCC 35469 7121762 YP_002384828.1 CDS coaA NC_011740.1 3873250 3874200 D catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 3873250..3874200 Escherichia fergusonii ATCC 35469 7120053 YP_002384829.1 CDS birA NC_011740.1 3874229 3875194 R catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase complement(3874229..3875194) Escherichia fergusonii ATCC 35469 7120908 YP_002384830.1 CDS murB NC_011740.1 3875191 3876219 R catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase complement(3875191..3876219) Escherichia fergusonii ATCC 35469 7121672 YP_002384831.1 CDS murI NC_011740.1 3881746 3882603 R converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase complement(3881746..3882603) Escherichia fergusonii ATCC 35469 7120383 YP_002384832.2 CDS btuB NC_011740.1 3882548 3884392 R involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space; vitamin B12/cobalamin outer membrane transporter complement(3882548..3884392) Escherichia fergusonii ATCC 35469 7120649 YP_002384833.1 CDS trmA NC_011740.1 3884761 3885861 D catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs; tRNA (uracil-5-)-methyltransferase 3884761..3885861 Escherichia fergusonii ATCC 35469 7121680 YP_002384834.1 CDS yijD NC_011740.1 3885901 3886260 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(3885901..3886260) Escherichia fergusonii ATCC 35469 7122159 YP_002384835.1 CDS fabR NC_011740.1 3886260 3886910 R negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis; DNA-binding transcriptional repressor FabR complement(3886260..3886910) Escherichia fergusonii ATCC 35469 7121859 YP_002384836.1 CDS EFER_3798 NC_011740.1 3887014 3888330 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; proton/ carboxylic acid permease complement(3887014..3888330) Escherichia fergusonii ATCC 35469 7123624 YP_002384837.1 CDS EFER_3799 NC_011740.1 3888374 3889540 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7730270; Product type e : enzyme; Hippurate hydrolase complement(3888374..3889540) Escherichia fergusonii ATCC 35469 7120313 YP_002384838.1 CDS sthA NC_011740.1 3889870 3891270 D catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase 3889870..3891270 Escherichia fergusonii ATCC 35469 7123679 YP_002384839.1 CDS oxyR NC_011740.1 3891253 3892170 R Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA; DNA-binding transcriptional regulator OxyR complement(3891253..3892170) Escherichia fergusonii ATCC 35469 7121951 YP_002384840.1 CDS argH NC_011740.1 3892437 3893810 R catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase complement(3892437..3893810) Escherichia fergusonii ATCC 35469 7119707 YP_002384841.1 CDS argB NC_011740.1 3893871 3894644 R catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase complement(3893871..3894644) Escherichia fergusonii ATCC 35469 7123178 YP_002384842.1 CDS argC NC_011740.1 3894655 3895659 R catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase complement(3894655..3895659) Escherichia fergusonii ATCC 35469 7120537 YP_002384843.1 CDS argE NC_011740.1 3895813 3896964 D catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase 3895813..3896964 Escherichia fergusonii ATCC 35469 7120538 YP_002384844.1 CDS ppc NC_011740.1 3897310 3899961 D catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase 3897310..3899961 Escherichia fergusonii ATCC 35469 7120539 YP_002384845.1 CDS yijP NC_011740.1 3900158 3901891 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 10456927; Product type pm : membrane component; hypothetical protein 3900158..3901891 Escherichia fergusonii ATCC 35469 7120107 YP_002384846.1 CDS yijO NC_011740.1 3902121 3902972 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator 3902121..3902972 Escherichia fergusonii ATCC 35469 7121862 YP_002384847.1 CDS frwD NC_011740.1 3902959 3903300 R FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog; fructose-like phosphotransferase EIIB subunit 3 complement(3902959..3903300) Escherichia fergusonii ATCC 35469 7123388 YP_002384848.1 CDS pflC NC_011740.1 3903302 3904180 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95291446, 14673546, 7773398; Product type e : enzyme; pyruvate formate lyase II activase complement(3903302..3904180) Escherichia fergusonii ATCC 35469 7123023 YP_002384849.1 CDS pflD NC_011740.1 3904146 3906443 R involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein; formate acetyltransferase 2 complement(3904146..3906443) Escherichia fergusonii ATCC 35469 7122584 YP_002384850.1 CDS frwB NC_011740.1 3906494 3906814 R FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS; PTS system fructose-like transporter subunit IIB complement(3906494..3906814) Escherichia fergusonii ATCC 35469 7122585 YP_002384851.1 CDS frwC NC_011740.1 3906825 3907904 R FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site; fructose-like permease EIIC subunit 2 complement(3906825..3907904) Escherichia fergusonii ATCC 35469 7123021 YP_002384852.1 CDS ptsA NC_011740.1 3908213 3910714 D Evidence 2b : Function of strongly homologous gene; PubMedId : 95291446, 7773398; Product type t : transporter; PTS system transporter protein Hpr /enzyme I /subunit IIA 3908213..3910714 Escherichia fergusonii ATCC 35469 7123022 YP_002384853.1 CDS fsaB NC_011740.1 3910726 3911388 D similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 3910726..3911388 Escherichia fergusonii ATCC 35469 7122314 YP_002384854.1 CDS gldA NC_011740.1 3911399 3912502 D forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 3911399..3912502 Escherichia fergusonii ATCC 35469 7123024 YP_002384855.1 CDS yijF NC_011740.1 3912621 3913238 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3912621..3913238 Escherichia fergusonii ATCC 35469 7120184 YP_002384856.1 CDS yijE NC_011740.1 3913263 3914168 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; permease complement(3913263..3914168) Escherichia fergusonii ATCC 35469 7121861 YP_002384857.1 CDS katG NC_011740.1 3914262 3916442 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90292022, 94209230, 3045098; Product type e : enzyme; catalase/hydroperoxidase HPI(I) complement(3914262..3916442) Escherichia fergusonii ATCC 35469 7121860 YP_002384858.1 CDS metF NC_011740.1 3916770 3917660 R MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase complement(3916770..3917660) Escherichia fergusonii ATCC 35469 7120800 YP_002384859.1 CDS EFER_3822 NC_011740.1 3918010 3918984 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3918010..3918984 Escherichia fergusonii ATCC 35469 7120918 YP_002384860.1 CDS EFER_3823 NC_011740.1 3919036 3920547 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; GntR family transcriptional regulator 3919036..3920547 Escherichia fergusonii ATCC 35469 7120314 YP_002384861.1 CDS EFER_3824 NC_011740.1 3920492 3921658 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; Alanine racemase 3 complement(3920492..3921658) Escherichia fergusonii ATCC 35469 7123138 YP_002384862.1 CDS glyAB NC_011740.1 3921598 3922899 R catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase complement(3921598..3922899) Escherichia fergusonii ATCC 35469 7120315 YP_002384863.1 CDS EFER_3828 NC_011740.1 3923910 3924284 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; decarboxylase 3923910..3924284 Escherichia fergusonii ATCC 35469 7120317 YP_002384864.1 CDS EFER_3829 NC_011740.1 3924364 3925917 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; phosphoesterase complement(3924364..3925917) Escherichia fergusonii ATCC 35469 7120318 YP_002384865.1 CDS EFER_3830 NC_011740.1 3926050 3927180 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3926050..3927180 Escherichia fergusonii ATCC 35469 7123139 YP_002384866.1 CDS metL NC_011740.1 3927144 3929576 R multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartate kinase II/homoserine dehydrogenase II complement(3927144..3929576) Escherichia fergusonii ATCC 35469 7120319 YP_002384867.1 CDS metB NC_011740.1 3929579 3930739 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87326410, 90148970, 3307782, 6361020, 9843488; Product type e : enzyme; cystathionine gamma-synthase, PLP-dependent complement(3929579..3930739) Escherichia fergusonii ATCC 35469 7120923 YP_002384868.1 CDS metJ NC_011740.1 3931016 3931333 D when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis; transcriptional repressor protein MetJ 3931016..3931333 Escherichia fergusonii ATCC 35469 7120915 YP_002384869.1 CDS yiiX NC_011740.1 3931393 3932001 D member of the NlpC/P60 superfamily of peptidases; peptidoglycan peptidase 3931393..3932001 Escherichia fergusonii ATCC 35469 7123776 YP_002384870.1 CDS EFER_3835 NC_011740.1 3932005 3932631 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3932005..3932631 Escherichia fergusonii ATCC 35469 7121858 YP_002384871.1 CDS rpmE NC_011740.1 3932686 3932898 R RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(3932686..3932898) Escherichia fergusonii ATCC 35469 7120320 YP_002384872.1 CDS priA NC_011740.1 3933101 3935299 D binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 3933101..3935299 Escherichia fergusonii ATCC 35469 7121116 YP_002384873.1 CDS cytR NC_011740.1 3935455 3936480 D negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins; DNA-binding transcriptional regulator CytR 3935455..3936480 Escherichia fergusonii ATCC 35469 7120125 YP_002384874.1 CDS ftsN NC_011740.1 3936574 3937518 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9282742, 93285993, 8509333; Product type cp : cell process; cell division protein FtsN 3936574..3937518 Escherichia fergusonii ATCC 35469 7122859 YP_002384875.1 CDS hslV NC_011740.1 3937611 3938141 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 3937611..3938141 Escherichia fergusonii ATCC 35469 7120150 YP_002384876.1 CDS hslU NC_011740.1 3938151 3939482 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 3938151..3939482 Escherichia fergusonii ATCC 35469 7122230 YP_002384877.1 CDS menA NC_011740.1 3939549 3940475 D catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 3939549..3940475 Escherichia fergusonii ATCC 35469 7122229 YP_002384878.1 CDS rraA NC_011740.1 3940568 3941053 D regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity; ribonuclease activity regulator protein RraA 3940568..3941053 Escherichia fergusonii ATCC 35469 7121256 YP_002384879.1 CDS yiiU NC_011740.1 3941115 3941360 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3941115..3941360) Escherichia fergusonii ATCC 35469 7121141 YP_002384880.1 CDS EFER_3845 NC_011740.1 3941450 3941608 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(3941450..3941608) Escherichia fergusonii ATCC 35469 7123387 YP_002384881.1 CDS glpF NC_011740.1 3941788 3942633 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12629974, 12948772, 14646142, 15004242, 90094250, 92210584, 11039922, 11101882, 11226336, 11964478, 1372899, 2544860, 6998951; Product type t : transporter; glycerol facilitator 3941788..3942633 Escherichia fergusonii ATCC 35469 7120321 YP_002384882.1 CDS glpK NC_011740.1 3942656 3944164 D Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 3942656..3944164 Escherichia fergusonii ATCC 35469 7120577 YP_002384883.1 CDS glpX NC_011740.1 3944277 3945287 D type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 3944277..3945287 Escherichia fergusonii ATCC 35469 7123720 YP_002384884.1 CDS fpr NC_011740.1 3945384 3946130 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 93194782, 94092163, 95050480, 95362685, 1400248, 2834327, 7961651, 8449868, 9149148; Product type e : enzyme; ferredoxin-NADP reductase 3945384..3946130 Escherichia fergusonii ATCC 35469 7120581 YP_002384885.1 CDS yiiT NC_011740.1 3946135 3946563 R with UspC and Usp E is involved in resistance to UV radiation; universal stress protein UspD complement(3946135..3946563) Escherichia fergusonii ATCC 35469 7123008 YP_002384886.1 CDS EFER_3851 NC_011740.1 3946591 3946965 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3946591..3946965) Escherichia fergusonii ATCC 35469 7121857 YP_002384887.1 CDS yiiR NC_011740.1 3947099 3947539 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(3947099..3947539) Escherichia fergusonii ATCC 35469 7120322 YP_002384888.1 CDS yiiQ NC_011740.1 3947640 3948239 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3947640..3948239 Escherichia fergusonii ATCC 35469 7123936 YP_002384889.1 CDS tpiA NC_011740.1 3948347 3949114 D Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 3948347..3949114 Escherichia fergusonii ATCC 35469 7123935 YP_002384890.1 CDS cdh NC_011740.1 3949170 3949961 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86008270, 2995360, 3158524; Product type e : enzyme; CDP-diacylglycerol pyrophosphatase complement(3949170..3949961) Escherichia fergusonii ATCC 35469 7122150 YP_002384891.1 CDS sbp NC_011740.1 3950023 3951012 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91161616, 2002055, 3158524, 8774726, 9298646; Product type t : transporter; sulfate transporter subunit complement(3950023..3951012) Escherichia fergusonii ATCC 35469 7120875 YP_002384892.1 CDS pfkA NC_011740.1 3951169 3952131 R catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase complement(3951169..3952131) Escherichia fergusonii ATCC 35469 7121753 YP_002384893.1 CDS fieF NC_011740.1 3952312 3953214 R member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers; ferrous iron efflux protein F complement(3952312..3953214) Escherichia fergusonii ATCC 35469 7122581 YP_002384894.1 CDS cpxP NC_011740.1 3953364 3953864 R repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates; repressor CpxP complement(3953364..3953864) Escherichia fergusonii ATCC 35469 7120018 YP_002384895.1 CDS cpxR NC_011740.1 3954015 3954713 D response regulator in two-component regulatory system with CpxA; part of the envelope stress response system; DNA-binding transcriptional regulator CpxR 3954015..3954713 Escherichia fergusonii ATCC 35469 7122799 YP_002384896.1 CDS cpxA NC_011740.1 3954710 3956083 D part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors; two-component sensor protein 3954710..3956083 Escherichia fergusonii ATCC 35469 7122800 YP_002384897.1 CDS yiiM NC_011740.1 3956143 3956817 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3956143..3956817) Escherichia fergusonii ATCC 35469 7122798 YP_002384898.1 CDS sodA NC_011740.1 3956887 3957507 R SodA; manganese binding; only present under aerobic conditions; destroys free radicals; superoxide dismutase complement(3956887..3957507) Escherichia fergusonii ATCC 35469 7121856 YP_002384899.1 CDS rhaT NC_011740.1 3957794 3958828 D transports L-rhamnose and L-lyxose into the cell; rhamnose-proton symporter 3957794..3958828 Escherichia fergusonii ATCC 35469 7123926 YP_002384900.1 CDS rhaR NC_011740.1 3958825 3959712 R activates the expression of rhaRS in response to L-rhamnose; transcriptional activator RhaR complement(3958825..3959712) Escherichia fergusonii ATCC 35469 7121399 YP_002384901.1 CDS rhaS NC_011740.1 3959745 3960581 R activates the expression of the rhaBAD operon and rhaT gene; transcriptional activator RhaS complement(3959745..3960581) Escherichia fergusonii ATCC 35469 7123314 YP_002384902.1 CDS rhaB NC_011740.1 3960870 3962339 D catalyzes the ATP-dependent phosphorylation of rhamnulose; rhamnulokinase 3960870..3962339 Escherichia fergusonii ATCC 35469 7121398 YP_002384903.1 CDS rhaA NC_011740.1 3962336 3963595 D catalyzes the formation of L-rhamnulose from L-rhamnose; L-rhamnose isomerase 3962336..3963595 Escherichia fergusonii ATCC 35469 7123861 YP_002384904.1 CDS rhaD NC_011740.1 3963678 3964502 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90128204, 93374854, 8396120; Product type e : enzyme; rhamnulose-1-phosphate aldolase 3963678..3964502 Escherichia fergusonii ATCC 35469 7121396 YP_002384905.1 CDS EFER_3870 NC_011740.1 3964526 3965722 D Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; alcohol dehydrogenase 3964526..3965722 Escherichia fergusonii ATCC 35469 7121397 YP_002384906.1 CDS yiiL NC_011740.1 3965719 3966033 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15060078; Product type e : enzyme; L-rhamnose mutarotase 3965719..3966033 Escherichia fergusonii ATCC 35469 7120323 YP_002384907.1 CDS frvA NC_011740.1 3966335 3966781 D with FrvBRX is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system involved in the transport and phosphorylation of sugars; possibly responsible for the sugar specificity of the system; fructose-like phosphotransferase system subunit EIIA 3966335..3966781 Escherichia fergusonii ATCC 35469 7121855 YP_002384908.1 CDS frvB NC_011740.1 3966792 3968243 D Evidence 2b : Function of strongly homologous gene; PubMedId : 94290319; Product type t : transporter; PTS system transporter subunits IIBC 3966792..3968243 Escherichia fergusonii ATCC 35469 7123017 YP_002384909.1 CDS frvX NC_011740.1 3968233 3969303 D with FrvABR is part of the phosphoenolpyruvate-dependent sugar phosphotransferase system which may be involved in the transport and phosphorylation of sugars; fructose-specific phosphotransferase system protein FrvX 3968233..3969303 Escherichia fergusonii ATCC 35469 7123018 YP_002384910.1 CDS frvR NC_011740.1 3969303 3971051 D repressor of the frv operon, involved in phosphoenolpyruvate:sugar phosphotransferase system; frv operon regulatory protein 3969303..3971051 Escherichia fergusonii ATCC 35469 7123020 YP_002384911.1 CDS EFER_3876 NC_011740.1 3971167 3977481 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3304658, 1693333; Product type f : factor; intimin 3971167..3977481 Escherichia fergusonii ATCC 35469 7123019 YP_002384912.1 CDS EFER_3879 NC_011740.1 3978838 3981144 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3978838..3981144) Escherichia fergusonii ATCC 35469 7121854 YP_002384913.1 CDS htpG NC_011740.1 3981146 3982981 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 2124707; Product type f : factor; Hsp90xo molecular chaperone complement(3981146..3982981) Escherichia fergusonii ATCC 35469 7120325 YP_002384914.1 CDS fdhD NC_011740.1 3983292 3984128 R involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; formate dehydrogenase accessory protein complement(3983292..3984128) Escherichia fergusonii ATCC 35469 7123446 YP_002384915.1 CDS fdoG NC_011740.1 3984322 3987372 D Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; formate dehydrogenase-O, large subunit 3984322..3987372 Escherichia fergusonii ATCC 35469 7119994 YP_002384916.1 CDS fdoH NC_011740.1 3987385 3988287 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91317715, 8522521, 9852007; Product type c : carrier; formate dehydrogenase-O, Fe-S subunit 3987385..3988287 Escherichia fergusonii ATCC 35469 7119999 YP_002384917.1 CDS fdoI NC_011740.1 3988284 3988919 D cytochrome b556(FDO) component; heme containing; formate dehydrogenase-O subunit gamma 3988284..3988919 Escherichia fergusonii ATCC 35469 7120000 YP_002384918.1 CDS fdhE NC_011740.1 3988916 3989845 D required for the formation of active formate dehydrogenase; formate dehydrogenase accessory protein FdhE 3988916..3989845 Escherichia fergusonii ATCC 35469 7120001 YP_002384919.1 CDS yiiE NC_011740.1 3990190 3990438 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator complement(3990190..3990438) Escherichia fergusonii ATCC 35469 7119995 YP_002384920.1 CDS EFER_3888 NC_011740.1 3990826 3991104 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(3990826..3991104) Escherichia fergusonii ATCC 35469 7121852 YP_002384921.1 CDS yiiD NC_011740.1 3991547 3992536 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; acetyltransferase complement(3991547..3992536) Escherichia fergusonii ATCC 35469 7120326 YP_002384922.1 CDS dtd NC_011740.1 3992533 3992970 R hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase complement(3992533..3992970) Escherichia fergusonii ATCC 35469 7121851 YP_002384923.1 CDS rbn NC_011740.1 3992967 3993839 R RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease; ribonuclease BN complement(3992967..3993839) Escherichia fergusonii ATCC 35469 7124130 YP_002384924.1 CDS yihX NC_011740.1 3993833 3994432 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; phosphatase complement(3993833..3994432) Escherichia fergusonii ATCC 35469 7122347 YP_002384925.1 CDS EFER_3895 NC_011740.1 3994785 3995630 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3994785..3995630 Escherichia fergusonii ATCC 35469 7121850 YP_002384926.1 CDS EFER_3896 NC_011740.1 3995631 3996677 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3995631..3996677 Escherichia fergusonii ATCC 35469 7123681 YP_002384927.1 CDS EFER_3897 NC_011740.1 3996670 3997542 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; metal-dependent hydrolase 3996670..3997542 Escherichia fergusonii ATCC 35469 7120327 YP_002384928.1 CDS EFER_3898 NC_011740.1 3997523 3998773 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 3997523..3998773 Escherichia fergusonii ATCC 35469 7120328 YP_002384929.1 CDS EFER_3899 NC_011740.1 3998770 3999627 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 3998770..3999627 Escherichia fergusonii ATCC 35469 7123682 YP_002384930.1 CDS EFER_3900 NC_011740.1 3999624 4000319 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15808744; Product type pe : enzyme; phosphatase 3999624..4000319 Escherichia fergusonii ATCC 35469 7120913 YP_002384931.1 CDS bipA NC_011740.1 4000410 4002233 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9642082, 7783627, 9298646, 9622352; Product type f : factor; GTP-binding protein complement(4000410..4002233) Escherichia fergusonii ATCC 35469 7120976 YP_002384932.1 CDS EFER_3902 NC_011740.1 4002326 4002478 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4002326..4002478 Escherichia fergusonii ATCC 35469 7121671 YP_002384933.1 CDS glnA NC_011740.1 4002606 4004015 D forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; glutamine synthetase 4002606..4004015 Escherichia fergusonii ATCC 35469 7123785 YP_002384934.1 CDS glnL NC_011740.1 4004189 4005238 D sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation; nitrogen regulation protein NR(II) 4004189..4005238 Escherichia fergusonii ATCC 35469 7120193 YP_002384935.1 CDS glnG NC_011740.1 4005250 4006659 D response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54; nitrogen regulation protein NR(I) 4005250..4006659 Escherichia fergusonii ATCC 35469 7120199 YP_002384936.1 CDS tdh NC_011740.1 4007011 4008036 R converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase complement(4007011..4008036) Escherichia fergusonii ATCC 35469 7120197 YP_002384937.1 CDS kbl NC_011740.1 4008046 4009914 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8157607; Product type e : enzyme; 2-amino-3-ketobutyrate coenzyme A ligase complement(4008046..4009914) Escherichia fergusonii ATCC 35469 7121983 YP_002384938.1 CDS rfaD NC_011740.1 4009456 4010388 D catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose; ADP-L-glycero-D-manno-heptose-6-epimerase 4009456..4010388 Escherichia fergusonii ATCC 35469 7123757 YP_002384939.1 CDS waaF NC_011740.1 4010398 4011444 D catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core; ADP-heptose--LPS heptosyltransferase 4010398..4011444 Escherichia fergusonii ATCC 35469 7122661 YP_002384940.1 CDS waaC NC_011740.1 4011448 4012404 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20507564, 92250420, 93239678, 9446588, 1624462, 8478319; Product type e : enzyme; ADP-heptose--LPS heptosyltransferase 4011448..4012404 Escherichia fergusonii ATCC 35469 7122662 YP_002384941.1 CDS rfaL NC_011740.1 4012443 4013660 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1657881; Product type e : enzyme; O-antigen ligase 4012443..4013660 Escherichia fergusonii ATCC 35469 7122660 YP_002384942.1 CDS rfaK NC_011740.1 4013713 4014855 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1657881; Product type e : enzyme; Lipopolysaccharide 1, 2-N-acetylglucosaminetransferase complement(4013713..4014855) Escherichia fergusonii ATCC 35469 7121389 YP_002384943.1 CDS waaZ NC_011740.1 4014908 4015717 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12591884, 92250420, 92325067, 93054344; Product type pe : enzyme; lipopolysaccharide core biosynthesis protein complement(4014908..4015717) Escherichia fergusonii ATCC 35469 7121388 YP_002384944.1 CDS waaY NC_011740.1 4015789 4016487 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92250420, 92325067, 9756860; Product type e : enzyme; lipopolysaccharide core biosynthesis protein complement(4015789..4016487) Escherichia fergusonii ATCC 35469 7123469 YP_002384945.1 CDS waaJ NC_011740.1 4016505 4017521 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92210496, 92250420, 92325066, 99251135, 1624461; Product type e : enzyme; UDP-D-glucose:(galactosyl)lipopolysaccharide glucosyltransferase complement(4016505..4017521) Escherichia fergusonii ATCC 35469 7122363 YP_002384946.1 CDS waaI NC_011740.1 4017561 4018580 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92210496, 92250420, 92325066, 9765561, 1624461; Product type e : enzyme; UDP-D-galactose:(glucosyl)lipopolysaccharide- alpha-1,3-D-galactosyltransferase complement(4017561..4018580) Escherichia fergusonii ATCC 35469 7122665 YP_002384947.1 CDS EFER_3918 NC_011740.1 4019365 4020333 D Evidence 2b : Function of strongly homologous gene; PubMedId : 2993802; Product type pe : enzyme; transposase, IS903.B 4019365..4020333 Escherichia fergusonii ATCC 35469 7122659 YP_002384948.1 CDS EFER_3920 NC_011740.1 4020907 4021851 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8910446; Product type e : enzyme; UDP-glucose:glucosyl LPS a 1, 2-glucosyltransferase complement(4020907..4021851) Escherichia fergusonii ATCC 35469 7124081 YP_002384949.1 CDS waaP NC_011740.1 4021864 4022661 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21101922, 92121133, 92210496, 9756860, 1732225; Product type e : enzyme; kinase that phosphorylates core heptose of lipopolysaccharide complement(4021864..4022661) Escherichia fergusonii ATCC 35469 7120978 YP_002384950.1 CDS waaG NC_011740.1 4022654 4023778 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92121133, 92210496, 92250420, 1447141, 1732225, 7988890; Product type e : enzyme; glucosyltransferase I complement(4022654..4023778) Escherichia fergusonii ATCC 35469 7123515 YP_002384951.1 CDS waaQ NC_011740.1 4023775 4024809 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92121133, 92250420, 93054344, 9756860, 1447141, 1732225; Product type e : enzyme; lipopolysaccharide core biosynthesis protein complement(4023775..4024809) Escherichia fergusonii ATCC 35469 7122663 YP_002384952.1 CDS kdtA NC_011740.1 4025251 4026528 D catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 4025251..4026528 Escherichia fergusonii ATCC 35469 7124016 YP_002384953.1 CDS coaD NC_011740.1 4026536 4027015 D Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 4026536..4027015 Escherichia fergusonii ATCC 35469 7120810 YP_002384954.1 CDS mutM NC_011740.1 4027054 4027863 R Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase complement(4027054..4027863) Escherichia fergusonii ATCC 35469 7120909 YP_002384955.1 CDS rpmG NC_011740.1 4027961 4028128 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 complement(4027961..4028128) Escherichia fergusonii ATCC 35469 7123197 YP_002384956.1 CDS rpmB NC_011740.1 4028149 4028385 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(4028149..4028385) Escherichia fergusonii ATCC 35469 7123268 YP_002384957.1 CDS radC NC_011740.1 4028602 4029270 R Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC complement(4028602..4029270) Escherichia fergusonii ATCC 35469 7121113 YP_002384958.1 CDS dfp NC_011740.1 4029442 4030662 D catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 4029442..4030662 Escherichia fergusonii ATCC 35469 7123930 YP_002384959.1 CDS dut NC_011740.1 4030643 4031098 D catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 4030643..4031098 Escherichia fergusonii ATCC 35469 7124120 YP_002384960.1 CDS slmA NC_011740.1 4031205 4031801 D FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly; nucleoid occlusion protein 4031205..4031801 Escherichia fergusonii ATCC 35469 7122930 YP_002384961.1 CDS EFER_3933 NC_011740.1 4031845 4032816 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2466573; Product type pe : enzyme; retron-type reverse transcriptase complement(4031845..4032816) Escherichia fergusonii ATCC 35469 7123992 YP_002384962.1 CDS pyrE NC_011740.1 4033102 4033743 R involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase complement(4033102..4033743) Escherichia fergusonii ATCC 35469 7123786 YP_002384963.1 CDS rph NC_011740.1 4033809 4034549 R RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH complement(4033809..4034549) Escherichia fergusonii ATCC 35469 7122335 YP_002384964.1 CDS yicC NC_011740.1 4034652 4035515 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4034652..4035515 Escherichia fergusonii ATCC 35469 7121435 YP_002384965.1 CDS yicG NC_011740.1 4035766 4036383 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 4035766..4036383 Escherichia fergusonii ATCC 35469 7122545 YP_002384966.1 CDS gmk NC_011740.1 4038321 4038944 D Essential for recycling GMP and indirectly, cGMP; guanylate kinase 4038321..4038944 Escherichia fergusonii ATCC 35469 7120834 YP_002384967.1 CDS rpoZ NC_011740.1 4038999 4039274 D promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 4038999..4039274 Escherichia fergusonii ATCC 35469 7120594 YP_002384968.1 CDS spoT NC_011740.1 4039293 4041401 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12224635, 89255395, 93266525, 94068533, 2005134, 2549050; Product type e : enzyme; bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase 4039293..4041401 Escherichia fergusonii ATCC 35469 7123813 YP_002384969.1 CDS trmH NC_011740.1 4041408 4042097 D specifically modifies tRNA at position G18; tRNA guanosine-2'-O-methyltransferase 4041408..4042097 Escherichia fergusonii ATCC 35469 7121809 YP_002384970.1 CDS recG NC_011740.1 4042103 4044184 D catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 4042103..4044184 Escherichia fergusonii ATCC 35469 7122162 YP_002384971.1 CDS EFER_3945 NC_011740.1 4044169 4045035 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4044169..4045035) Escherichia fergusonii ATCC 35469 7119960 YP_002384972.1 CDS gltS NC_011740.1 4045038 4046243 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91203811, 93106943, 1544582, 2017136, 2254324; Product type t : transporter; glutamate transporter complement(4045038..4046243) Escherichia fergusonii ATCC 35469 7120979 YP_002384973.1 CDS yicE NC_011740.1 4046474 4047865 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter 4046474..4047865 Escherichia fergusonii ATCC 35469 7120587 YP_002384974.1 CDS yicH NC_011740.1 4047987 4049696 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4047987..4049696 Escherichia fergusonii ATCC 35469 7123495 YP_002384975.1 CDS yicI NC_011740.1 4049748 4052066 R catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides; alpha-xylosidase complement(4049748..4052066) Escherichia fergusonii ATCC 35469 7121816 YP_002384976.1 CDS yicJ NC_011740.1 4052076 4053458 R may be involved in the transport of galactosides-pentoses-hexuronides; transporter complement(4052076..4053458) Escherichia fergusonii ATCC 35469 7121817 YP_002384977.1 CDS EFER_3951 NC_011740.1 4053769 4054935 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4053769..4054935 Escherichia fergusonii ATCC 35469 7123093 YP_002384978.1 CDS EFER_3952 NC_011740.1 4055128 4055625 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4055128..4055625 Escherichia fergusonii ATCC 35469 7120980 YP_002384979.1 CDS yicL NC_011740.1 4055749 4056705 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 4055749..4056705 Escherichia fergusonii ATCC 35469 7120981 YP_002384980.1 CDS yicS NC_011740.1 4056819 4057112 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4056819..4057112 Escherichia fergusonii ATCC 35469 7121819 YP_002384981.1 CDS EFER_3955 NC_011740.1 4057149 4058141 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15223311; Product type pr : regulator; LacI family transcriptional regulator complement(4057149..4058141) Escherichia fergusonii ATCC 35469 7121820 YP_002384982.1 CDS EFER_3956 NC_011740.1 4058388 4058711 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; PTS system cellobiose/chitosan transporter subunit IIB 4058388..4058711 Escherichia fergusonii ATCC 35469 7120982 YP_002384983.1 CDS EFER_3957 NC_011740.1 4058724 4060055 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; PTS system cellobiose/chitosan transporter subunit IIC 4058724..4060055 Escherichia fergusonii ATCC 35469 7120983 YP_002384984.1 CDS EFER_3958 NC_011740.1 4060055 4061473 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; glycosyl phosphatase 4060055..4061473 Escherichia fergusonii ATCC 35469 7120984 YP_002384985.1 CDS EFER_3959 NC_011740.1 4061455 4061772 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; chitobiose/cellobiose phosphotransferase enzyme IIA component 4061455..4061772 Escherichia fergusonii ATCC 35469 7120985 YP_002384986.1 CDS EFER_3960 NC_011740.1 4061959 4063353 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; outer membrane porin 4061959..4063353 Escherichia fergusonii ATCC 35469 7120986 YP_002384987.1 CDS yicN NC_011740.1 4063372 4063824 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4063372..4063824) Escherichia fergusonii ATCC 35469 7120987 YP_002384988.1 CDS ade NC_011740.1 4064110 4065876 D catalyzes the formation of hypoxanthine from adenine; in E. coli this activity has been detected in mutant strains but not in wild type; cryptic adenine deaminase 4064110..4065876 Escherichia fergusonii ATCC 35469 7123929 YP_002384989.1 CDS uhpT NC_011740.1 4065923 4067314 R cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate; sugar phosphate antiporter complement(4065923..4067314) Escherichia fergusonii ATCC 35469 7122273 YP_002384990.1 CDS uhpC NC_011740.1 4067452 4068771 R membrane protein regulates uhpT expression; regulatory protein UhpC complement(4067452..4068771) Escherichia fergusonii ATCC 35469 7122630 YP_002384991.1 CDS uhpB NC_011740.1 4068781 4070283 R Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph; sensory histidine kinase UhpB complement(4068781..4070283) Escherichia fergusonii ATCC 35469 7122629 YP_002384992.1 CDS uhpA NC_011740.1 4070283 4070873 R response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter; DNA-binding transcriptional activator UhpA complement(4070283..4070873) Escherichia fergusonii ATCC 35469 7123510 YP_002384993.1 CDS ilvN NC_011740.1 4070946 4071236 R with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit; acetolactate synthase 1 regulatory subunit complement(4070946..4071236) Escherichia fergusonii ATCC 35469 7123509 YP_002384994.1 CDS ilvB NC_011740.1 4071240 4072928 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 2989782, 85242083, 92380929, 2989781; Product type e : enzyme; acetolactate synthase catalytic subunit complement(4071240..4072928) Escherichia fergusonii ATCC 35469 7120735 YP_002384996.1 CDS ivbL NC_011740.1 4073034 4073132 R Evidence 1c : Function experimentally demonstrated in the studied genus; Product type l : leader peptide; ilvB operon leader peptide complement(4073034..4073132) Escherichia fergusonii ATCC 35469 7120727 YP_002384997.1 CDS emrD NC_011740.1 4074065 4075249 D multidrug efflux protein involved in adaptation to low energy shock; multidrug resistance protein D 4074065..4075249 Escherichia fergusonii ATCC 35469 7123755 YP_002384998.1 CDS dsdC NC_011740.1 4075273 4076205 R regulates the synthesis and expression of the dsdXA operon and dadA gene; DNA-binding transcriptional regulator DsdC complement(4075273..4076205) Escherichia fergusonii ATCC 35469 7122947 YP_002384999.1 CDS dsdX NC_011740.1 4076418 4077755 D member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function; permease DsdX 4076418..4077755 Escherichia fergusonii ATCC 35469 7124129 YP_002385000.1 CDS dsdA NC_011740.1 4077773 4079101 D catalyzes the formation of pyruvate from serine; D-serine dehydratase 4077773..4079101 Escherichia fergusonii ATCC 35469 7122924 YP_002385001.1 CDS EFER_3974 NC_011740.1 4079109 4079618 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 11222759; Product type pr : regulator; sulfur metabolism regulator complement(4079109..4079618) Escherichia fergusonii ATCC 35469 7124128 YP_002385002.1 CDS yidG NC_011740.1 4079631 4080017 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(4079631..4080017) Escherichia fergusonii ATCC 35469 7123787 YP_002385003.1 CDS yidH NC_011740.1 4079983 4080330 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(4079983..4080330) Escherichia fergusonii ATCC 35469 7121825 YP_002385004.1 CDS EFER_3977 NC_011740.1 4080650 4081972 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; 6-phospho-glucosidase complement(4080650..4081972) Escherichia fergusonii ATCC 35469 7121826 YP_002385005.1 CDS EFER_3978 NC_011740.1 4081972 4083582 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; PTS system alpha-glucoside-specific transporter subunit IICB complement(4081972..4083582) Escherichia fergusonii ATCC 35469 7120988 YP_002385006.1 CDS yidP NC_011740.1 4083877 4084593 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator 4083877..4084593 Escherichia fergusonii ATCC 35469 7120989 YP_002385007.1 CDS yidE NC_011740.1 4084590 4086359 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1356969; Product type pt : transporter; hypothetical protein complement(4084590..4086359) Escherichia fergusonii ATCC 35469 7121827 YP_002385008.1 CDS ibpB NC_011740.1 4086373 4086840 R 16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent; heat shock chaperone IbpB complement(4086373..4086840) Escherichia fergusonii ATCC 35469 7121824 YP_002385009.1 CDS ibpA NC_011740.1 4086913 4087326 R with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; heat shock protein IbpA complement(4086913..4087326) Escherichia fergusonii ATCC 35469 7120719 YP_002385010.1 CDS yidQ NC_011740.1 4087632 4087964 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 4087632..4087964 Escherichia fergusonii ATCC 35469 7120718 YP_002385011.1 CDS yidR NC_011740.1 4087966 4089180 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4087966..4089180) Escherichia fergusonii ATCC 35469 7121828 YP_002385012.1 CDS cbrA NC_011740.1 4089260 4090381 D FAD/NAD(P)-binding domain; oxidoreductase 4089260..4090381 Escherichia fergusonii ATCC 35469 7121829 YP_002385013.1 CDS dgoT NC_011740.1 4090342 4091634 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 79020349; Product type t : transporter; D-galactonate transporter complement(4090342..4091634) Escherichia fergusonii ATCC 35469 7120863 YP_002385014.1 CDS dgoD NC_011740.1 4091754 4092902 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 79020349; Product type e : enzyme; galactonate dehydratase complement(4091754..4092902) Escherichia fergusonii ATCC 35469 7122896 YP_002385015.1 CDS dgoA NC_011740.1 4092899 4093516 R catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase complement(4092899..4093516) Escherichia fergusonii ATCC 35469 7122894 YP_002385016.1 CDS dgoK NC_011740.1 4093500 4094378 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 79020349; Product type e : enzyme; 2-oxo-3-deoxygalactonate kinase complement(4093500..4094378) Escherichia fergusonii ATCC 35469 7122893 YP_002385017.1 CDS dgoR NC_011740.1 4094375 4095064 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 79020349; Product type pr : regulator; DNA-binding transcriptional regulator complement(4094375..4095064) Escherichia fergusonii ATCC 35469 7122895 YP_002385018.1 CDS yidX NC_011740.1 4095342 4095998 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; hypothetical protein 4095342..4095998 Escherichia fergusonii ATCC 35469 7124121 YP_002385019.1 CDS yidA NC_011740.1 4096044 4096856 R YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins; sugar phosphatase complement(4096044..4096856) Escherichia fergusonii ATCC 35469 7121830 YP_002385020.1 CDS yidB NC_011740.1 4096971 4097369 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4096971..4097369) Escherichia fergusonii ATCC 35469 7121821 YP_002385021.1 CDS gyrB NC_011740.1 4097535 4099949 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B complement(4097535..4099949) Escherichia fergusonii ATCC 35469 7123382 YP_002385022.1 CDS recF NC_011740.1 4099978 4101051 R Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F complement(4099978..4101051) Escherichia fergusonii ATCC 35469 7120628 YP_002385023.1 CDS dnaN NC_011740.1 4101051 4102151 R binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta complement(4101051..4102151) Escherichia fergusonii ATCC 35469 7122362 YP_002385024.1 CDS dnaA NC_011740.1 4102156 4103568 R binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein complement(4102156..4103568) Escherichia fergusonii ATCC 35469 7122913 YP_002385025.1 CDS rpmH NC_011740.1 4104163 4104303 D in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 4104163..4104303 Escherichia fergusonii ATCC 35469 7124123 YP_002385026.1 CDS rnpA NC_011740.1 4104320 4104679 D protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 4104320..4104679 Escherichia fergusonii ATCC 35469 7123269 YP_002385027.1 CDS yidD NC_011740.1 4104643 4104900 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4104643..4104900 Escherichia fergusonii ATCC 35469 7123867 YP_002385028.1 CDS yidC NC_011740.1 4104903 4106549 D functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 4104903..4106549 Escherichia fergusonii ATCC 35469 7121823 YP_002385029.1 CDS trmE NC_011740.1 4106655 4108019 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 4106655..4108019 Escherichia fergusonii ATCC 35469 7121822 YP_002385030.1 CDS tnaC NC_011740.1 4108262 4108336 D Evidence 1c : Function experimentally demonstrated in the studied genus; Product type l : leader peptide; tryptophanase leader peptide 4108262..4108336 Escherichia fergusonii ATCC 35469 7123989 YP_002385031.1 CDS tnaA NC_011740.1 4108557 4109972 D tryptophan indole-lyase; catalyzes the formation of indole and pyruvate from tryptophan; tryptophanase 4108557..4109972 Escherichia fergusonii ATCC 35469 7122139 YP_002385032.1 CDS tnaB NC_011740.1 4110064 4111311 D tryptophan transporter of low affinity; tryptophan permease TnaB 4110064..4111311 Escherichia fergusonii ATCC 35469 7122137 YP_002385033.1 CDS mdtL NC_011740.1 4111444 4112619 D Confers resistance to chloramphenicol; multidrug efflux system protein MdtL 4111444..4112619 Escherichia fergusonii ATCC 35469 7122138 YP_002385034.1 CDS yidZ NC_011740.1 4112585 4113553 D Involved in anaerobic NO protection; DNA-binding transcriptional regulator YidZ 4112585..4113553 Escherichia fergusonii ATCC 35469 7121255 YP_002385035.1 CDS EFER_4008 NC_011740.1 4113701 4114450 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; phosphopantetheinyl transferase 4113701..4114450 Escherichia fergusonii ATCC 35469 7123931 YP_002385036.1 CDS yieF NC_011740.1 4114461 4115027 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14766567; Product type e : enzyme; chromate reductase, Class I, flavoprotein 4114461..4115027 Escherichia fergusonii ATCC 35469 7123788 YP_002385037.1 CDS EFER_4010 NC_011740.1 4115109 4115264 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4115109..4115264) Escherichia fergusonii ATCC 35469 7123383 YP_002385038.1 CDS EFER_4011 NC_011740.1 4115268 4115459 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4115268..4115459) Escherichia fergusonii ATCC 35469 7120990 YP_002385039.1 CDS yieG NC_011740.1 4115505 4116842 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(4115505..4116842) Escherichia fergusonii ATCC 35469 7120991 YP_002385040.1 CDS yieH NC_011740.1 4117008 4117673 D YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily; 6-phosphogluconate phosphatase 4117008..4117673 Escherichia fergusonii ATCC 35469 7121831 YP_002385041.1 CDS yieI NC_011740.1 4117740 4118213 D might be involved in hypersensitivity to nitrofurzone; inner membrane protein 4117740..4118213 Escherichia fergusonii ATCC 35469 7121832 YP_002385042.1 CDS EFER_4015 NC_011740.1 4118262 4118843 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4118262..4118843 Escherichia fergusonii ATCC 35469 7121833 YP_002385043.1 CDS yieK NC_011740.1 4118899 4119615 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; 6-phosphogluconolactonase complement(4118899..4119615) Escherichia fergusonii ATCC 35469 7120992 YP_002385044.1 CDS yieL NC_011740.1 4119630 4120826 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; xylanase complement(4119630..4120826) Escherichia fergusonii ATCC 35469 7121834 YP_002385045.1 CDS bglH NC_011740.1 4120826 4122442 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10027967; Product type t : transporter; carbohydrate-specific outer membrane porin, cryptic complement(4120826..4122442) Escherichia fergusonii ATCC 35469 7121835 YP_002385046.1 CDS bglB NC_011740.1 4122527 4123921 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87222180, 88297127, 92334140, 3034860, 3309161; Product type e : enzyme; cryptic phospho-beta-glucosidase B complement(4122527..4123921) Escherichia fergusonii ATCC 35469 7123359 YP_002385047.1 CDS bglF NC_011740.1 4123940 4125889 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system beta-glucoside-specific transporter subunit IIABC complement(4123940..4125889) Escherichia fergusonii ATCC 35469 7121661 YP_002385048.1 CDS bglG NC_011740.1 4125948 4126784 R positive regulator of the beta-glucoside operon; transcriptional antiterminator; transcriptional antiterminator BglG complement(4125948..4126784) Escherichia fergusonii ATCC 35469 7121662 YP_002385049.1 CDS phoU NC_011740.1 4127070 4127795 R regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon; transcriptional regulator PhoU complement(4127070..4127795) Escherichia fergusonii ATCC 35469 7121663 YP_002385050.1 CDS pstB NC_011740.1 4127810 4128583 R ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein complement(4127810..4128583) Escherichia fergusonii ATCC 35469 7122604 YP_002385051.1 CDS pstA NC_011740.1 4128675 4129565 R Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PtsA complement(4128675..4129565) Escherichia fergusonii ATCC 35469 7122308 YP_002385052.1 CDS pstC NC_011740.1 4129565 4130524 R part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions; phosphate transporter permease subunit PstC complement(4129565..4130524) Escherichia fergusonii ATCC 35469 7123460 YP_002385053.1 CDS pstS NC_011740.1 4130610 4131650 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90133909, 2215649, 6321434, 6365894, 9228942, 9298646, 9671506; Product type t : transporter; phosphate ABC transporter substrate-binding protein complement(4130610..4131650) Escherichia fergusonii ATCC 35469 7122309 YP_002385054.1 CDS glmS NC_011740.1 4131921 4133750 R Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase complement(4131921..4133750) Escherichia fergusonii ATCC 35469 7122310 YP_002385055.1 CDS glmU NC_011740.1 4133912 4135282 R forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase complement(4133912..4135282) Escherichia fergusonii ATCC 35469 7123119 YP_002385056.1 CDS EFER_4029 NC_011740.1 4135558 4136256 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; hypothetical protein complement(4135558..4136256) Escherichia fergusonii ATCC 35469 7120192 YP_002385057.1 CDS atpC NC_011740.1 4136453 4136872 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon complement(4136453..4136872) Escherichia fergusonii ATCC 35469 7120993 YP_002385058.1 CDS atpD NC_011740.1 4136893 4138275 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta complement(4136893..4138275) Escherichia fergusonii ATCC 35469 7123354 YP_002385059.1 CDS atpG NC_011740.1 4138302 4139165 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma complement(4138302..4139165) Escherichia fergusonii ATCC 35469 7121635 YP_002385060.1 CDS atpA NC_011740.1 4139216 4140757 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha complement(4139216..4140757) Escherichia fergusonii ATCC 35469 7121638 YP_002385061.1 CDS atpH NC_011740.1 4140770 4141303 R Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta complement(4140770..4141303) Escherichia fergusonii ATCC 35469 7121633 YP_002385062.1 CDS atpF NC_011740.1 4141318 4141788 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B complement(4141318..4141788) Escherichia fergusonii ATCC 35469 7123900 YP_002385063.1 CDS atpE NC_011740.1 4141850 4142089 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C complement(4141850..4142089) Escherichia fergusonii ATCC 35469 7121637 YP_002385064.1 CDS atpB NC_011740.1 4142136 4142951 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A complement(4142136..4142951) Escherichia fergusonii ATCC 35469 7121636 YP_002385065.1 CDS atpI NC_011740.1 4142960 4143340 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation; F0F1 ATP synthase subunit I complement(4142960..4143340) Escherichia fergusonii ATCC 35469 7121634 YP_002385066.1 CDS gidB NC_011740.1 4143955 4144578 R glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB complement(4143955..4144578) Escherichia fergusonii ATCC 35469 7121639 YP_002385067.1 CDS gidA NC_011740.1 4144642 4146531 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA complement(4144642..4146531) Escherichia fergusonii ATCC 35469 7123659 YP_002385068.1 CDS mioC NC_011740.1 4146910 4147353 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin complement(4146910..4147353) Escherichia fergusonii ATCC 35469 7123658 YP_002385069.1 CDS asnC NC_011740.1 4147443 4147901 R transcriptional repressor of asnA which codes for aspartate-ammonia ligase; DNA-binding transcriptional regulator AsnC complement(4147443..4147901) Escherichia fergusonii ATCC 35469 7120935 YP_002385070.1 CDS asnA NC_011740.1 4148053 4149045 D catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA 4148053..4149045 Escherichia fergusonii ATCC 35469 7120569 YP_002385071.1 CDS yieM NC_011740.1 4149050 4150501 R contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA; hypothetical protein complement(4149050..4150501) Escherichia fergusonii ATCC 35469 7120567 YP_002385072.1 CDS ravA NC_011740.1 4150495 4152015 R interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase; regulatory ATPase RavA complement(4150495..4152015) Escherichia fergusonii ATCC 35469 7121836 YP_002385073.1 CDS trkD NC_011740.1 4152213 4154081 D Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH; potassium transport protein Kup 4152213..4154081 Escherichia fergusonii ATCC 35469 7122345 YP_002385074.1 CDS rbsD NC_011740.1 4154248 4154667 D cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 4154248..4154667 Escherichia fergusonii ATCC 35469 7123434 YP_002385075.1 CDS rbsA NC_011740.1 4154675 4156180 D with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain; D-ribose transporter ATP-binding protein 4154675..4156180 Escherichia fergusonii ATCC 35469 7122350 YP_002385076.1 CDS rbsC NC_011740.1 4156185 4157150 D functions to transport ribose at high affinity; forms a complex with RbsA2C2B; ribose ABC transporter permease 4156185..4157150 Escherichia fergusonii ATCC 35469 7122348 YP_002385077.1 CDS rbsB NC_011740.1 4157175 4158065 D periplasmic substrate-binding component of the ATP-dependent ribose transport system; D-ribose transporter subunit RbsB 4157175..4158065 Escherichia fergusonii ATCC 35469 7122349 YP_002385078.1 CDS rbsK NC_011740.1 4158191 4159120 D catalyzes the formation of D-ribose 5-phosphate from ribose; ribokinase 4158191..4159120 Escherichia fergusonii ATCC 35469 7124026 YP_002385079.1 CDS rbsR NC_011740.1 4159124 4160116 D DNA-binding transcriptional repressor of ribose metabolism; transcriptional repressor RbsR 4159124..4160116 Escherichia fergusonii ATCC 35469 7122351 YP_002385080.1 CDS yieP NC_011740.1 4160157 4160861 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator complement(4160157..4160861) Escherichia fergusonii ATCC 35469 7122352 YP_002385081.1 CDS yjaB NC_011740.1 4166477 4166920 R Evidence 2b : Function of strongly homologous gene; Product type pe : enzyme; hypothetical protein complement(4166477..4166920) Escherichia fergusonii ATCC 35469 7120511 YP_002385082.1 CDS metA NC_011740.1 4167077 4168006 D catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 4167077..4168006 Escherichia fergusonii ATCC 35469 7121863 YP_002385083.1 CDS aceB NC_011740.1 4168275 4169876 D Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle; malate synthase 4168275..4169876 Escherichia fergusonii ATCC 35469 7123241 YP_002385084.1 CDS aceA NC_011740.1 4169906 4171210 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91295197, 92112731, 92353108, 2836370, 3049537, 3060852, 3276689, 3290857, 3291954, 7826335; Product type e : enzyme; isocitrate lyase 4169906..4171210 Escherichia fergusonii ATCC 35469 7123451 YP_002385085.1 CDS aceK NC_011740.1 4171259 4172992 D catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol; bifunctional isocitrate dehydrogenase kinase/phosphatase 4171259..4172992 Escherichia fergusonii ATCC 35469 7124009 YP_002385086.1 CDS EFER_4070 NC_011740.1 4173017 4174474 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3029675; Product type e : enzyme; DNA cytosine methylase 4173017..4174474 Escherichia fergusonii ATCC 35469 7122259 YP_002385087.1 CDS iclR NC_011740.1 4174522 4175346 R regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase; IclR family transcriptional regulator complement(4174522..4175346) Escherichia fergusonii ATCC 35469 7120994 YP_002385088.1 CDS metH NC_011740.1 4175546 4179229 D one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 4175546..4179229 Escherichia fergusonii ATCC 35469 7120722 YP_002385089.1 CDS EFER_4073 NC_011740.1 4179283 4179609 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4179283..4179609 Escherichia fergusonii ATCC 35469 7120920 YP_002385090.1 CDS EFER_4074 NC_011740.1 4179652 4180101 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4179652..4180101 Escherichia fergusonii ATCC 35469 7120995 YP_002385091.1 CDS yjbB NC_011740.1 4180272 4181903 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter 4180272..4181903 Escherichia fergusonii ATCC 35469 7120996 YP_002385092.1 CDS yaiL NC_011740.1 4181951 4182544 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15115803, 12878731, 13129938; Product type e : enzyme; nucleoprotein/polynucleotide-associated enzyme 4181951..4182544 Escherichia fergusonii ATCC 35469 7121865 YP_002385093.1 CDS EFER_4077 NC_011740.1 4182697 4183917 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968, 7652212; Product type e : enzyme; L-sorbose 1-phosphate reductase complement(4182697..4183917) Escherichia fergusonii ATCC 35469 7123258 YP_002385094.1 CDS EFER_4078 NC_011740.1 4183971 4184825 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968, 7700234; Product type t : transporter; sorbose permease IID component complement(4183971..4184825) Escherichia fergusonii ATCC 35469 7123251 YP_002385095.1 CDS EFER_4079 NC_011740.1 4184806 4185603 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968, 7700234; Product type t : transporter; PTS system sorbose-specific transporter subunit IIC complement(4184806..4185603) Escherichia fergusonii ATCC 35469 7120997 YP_002385096.1 CDS EFER_4080 NC_011740.1 4185671 4186162 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968, 7700234, 12662934; Product type t : transporter; PTS system sorbose-specific transporter subunit IIB complement(4185671..4186162) Escherichia fergusonii ATCC 35469 7120998 YP_002385097.1 CDS EFER_4081 NC_011740.1 4186162 4186569 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968; Product type t : transporter; PTS system sorbose-specific transporter subunit IIA complement(4186162..4186569) Escherichia fergusonii ATCC 35469 7120999 YP_002385098.1 CDS EFER_4082 NC_011740.1 4186579 4187430 R Converts D-sorbitol-dphosphate to D-fructose-6-phosphate; sorbitol-6-phosphate 2-dehydrogenase complement(4186579..4187430) Escherichia fergusonii ATCC 35469 7121000 YP_002385099.1 CDS EFER_4083 NC_011740.1 4187443 4188480 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7947968; Product type r : regulator; sorbitol/sorbose operon regulator complement(4187443..4188480) Escherichia fergusonii ATCC 35469 7121001 YP_002385100.1 CDS yjbC NC_011740.1 4188745 4189617 D catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA; 23S rRNA pseudouridine synthase F 4188745..4189617 Escherichia fergusonii ATCC 35469 7121002 YP_002385101.1 CDS EFER_4086 NC_011740.1 4189893 4191035 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1657881; Product type e : enzyme; lipopolysaccharide 1, 2-N-acetylglucosaminetransferase complement(4189893..4191035) Escherichia fergusonii ATCC 35469 7121868 YP_002385102.1 CDS yjbD NC_011740.1 4192210 4192482 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4192210..4192482) Escherichia fergusonii ATCC 35469 7121867 YP_002385103.1 CDS EFER_4089 NC_011740.1 4192796 4193008 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4192796..4193008 Escherichia fergusonii ATCC 35469 7123939 YP_002385104.1 CDS EFER_4090 NC_011740.1 4193012 4194139 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4193012..4194139 Escherichia fergusonii ATCC 35469 7121004 YP_002385105.1 CDS EFER_4091 NC_011740.1 4194136 4194936 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4194136..4194936 Escherichia fergusonii ATCC 35469 7123252 YP_002385106.1 CDS EFER_4092 NC_011740.1 4194966 4195694 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4194966..4195694) Escherichia fergusonii ATCC 35469 7121005 YP_002385107.1 CDS EFER_4093 NC_011740.1 4195908 4196363 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4195908..4196363) Escherichia fergusonii ATCC 35469 7121006 YP_002385108.1 CDS EFER_4094 NC_011740.1 4196360 4197067 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; phage tail fiber assembly protein complement(4196360..4197067) Escherichia fergusonii ATCC 35469 7123253 YP_002385109.1 CDS EFER_4095 NC_011740.1 4197064 4198767 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; side tail phage protein complement(4197064..4198767) Escherichia fergusonii ATCC 35469 7121007 YP_002385110.1 CDS EFER_4096 NC_011740.1 4198644 4199378 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; phage tail protein complement(4198644..4199378) Escherichia fergusonii ATCC 35469 7121008 YP_002385111.1 CDS EFER_4097 NC_011740.1 4199356 4200471 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; phage baseplate protein complement(4199356..4200471) Escherichia fergusonii ATCC 35469 7123254 YP_002385112.1 CDS EFER_4098 NC_011740.1 4200462 4200821 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; phage baseplate protein complement(4200462..4200821) Escherichia fergusonii ATCC 35469 7121009 YP_002385113.1 CDS EFER_4099 NC_011740.1 4200920 4201621 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7483254; Product type ps : structure; phage baseplate component complement(4200920..4201621) Escherichia fergusonii ATCC 35469 7121010 YP_002385114.1 CDS EFER_4100 NC_011740.1 4201631 4202671 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; control protein for phage late genes expression complement(4201631..4202671) Escherichia fergusonii ATCC 35469 7123789 YP_002385115.1 CDS EFER_4101 NC_011740.1 4202659 4202871 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; phage tail protein complement(4202659..4202871) Escherichia fergusonii ATCC 35469 7121011 YP_002385116.1 CDS EFER_4102 NC_011740.1 4202868 4203821 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; hypothetical protein complement(4202868..4203821) Escherichia fergusonii ATCC 35469 7123255 YP_002385117.1 CDS EFER_4103 NC_011740.1 4203821 4206196 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps : structure; phage tail protein complement(4203821..4206196) Escherichia fergusonii ATCC 35469 7121012 YP_002385118.1 CDS EFER_4104 NC_011740.1 4206297 4206425 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4206297..4206425) Escherichia fergusonii ATCC 35469 7121013 YP_002385119.1 CDS EFER_4105 NC_011740.1 4206385 4206702 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4206385..4206702) Escherichia fergusonii ATCC 35469 7123256 YP_002385120.1 CDS EFER_4106 NC_011740.1 4206753 4207277 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; phage tail core protein complement(4206753..4207277) Escherichia fergusonii ATCC 35469 7121014 YP_002385121.1 CDS EFER_4107 NC_011740.1 4207277 4208707 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1825255; Product type ps : structure; phage tail sheath protein complement(4207277..4208707) Escherichia fergusonii ATCC 35469 7121015 YP_002385122.1 CDS EFER_4108 NC_011740.1 4208691 4208888 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4208691..4208888) Escherichia fergusonii ATCC 35469 7123790 YP_002385123.1 CDS EFER_4109 NC_011740.1 4208885 4209340 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4208885..4209340) Escherichia fergusonii ATCC 35469 7121016 YP_002385124.1 CDS EFER_4110 NC_011740.1 4209458 4209772 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; inner membrane protein complement(4209458..4209772) Escherichia fergusonii ATCC 35469 7121017 YP_002385125.1 CDS EFER_4111 NC_011740.1 4209785 4210489 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; soluble lytic murein transglycosylase complement(4209785..4210489) Escherichia fergusonii ATCC 35469 7123791 YP_002385126.1 CDS EFER_4112 NC_011740.1 4210393 4210680 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm : membrane component; inner membrane protein complement(4210393..4210680) Escherichia fergusonii ATCC 35469 7121018 YP_002385127.1 CDS EFER_4113 NC_011740.1 4211218 4211562 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 7715460; Product type pr : regulator; transcriptional regulator 4211218..4211562 Escherichia fergusonii ATCC 35469 7121019 YP_002385128.1 CDS EFER_4114 NC_011740.1 4211734 4212669 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; zeta toxin; poison-antidote element complement(4211734..4212669) Escherichia fergusonii ATCC 35469 7123792 YP_002385129.1 CDS lysC NC_011740.1 4212808 4214157 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive; aspartate kinase III complement(4212808..4214157) Escherichia fergusonii ATCC 35469 7121020 YP_002385130.1 CDS pgi NC_011740.1 4214450 4216099 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 4214450..4216099 Escherichia fergusonii ATCC 35469 7121215 YP_002385131.1 CDS EFER_4118 NC_011740.1 4216435 4216683 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4216435..4216683) Escherichia fergusonii ATCC 35469 7122587 YP_002385132.1 CDS yjbF NC_011740.1 4216811 4217449 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp : lipoprotein; lipoprotein 4216811..4217449 Escherichia fergusonii ATCC 35469 7121021 YP_002385133.1 CDS yjbG NC_011740.1 4217446 4218183 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4217446..4218183 Escherichia fergusonii ATCC 35469 7121869 YP_002385134.1 CDS yjbH NC_011740.1 4218183 4220279 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; porin 4218183..4220279 Escherichia fergusonii ATCC 35469 7121870 YP_002385135.1 CDS yjbA NC_011740.1 4220400 4220810 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10986267; Product type pm : membrane component; phosphate-starvation-inducible protein PsiE 4220400..4220810 Escherichia fergusonii ATCC 35469 7121871 YP_002385136.1 CDS xylE NC_011740.1 4220854 4222329 R xylose/proton symporter; member of the major facilitator superfamily (MFS) of transporter; D-xylose transporter XylE complement(4220854..4222329) Escherichia fergusonii ATCC 35469 7123938 YP_002385137.1 CDS malG NC_011740.1 4222718 4223608 R with MalKFE is involved in the transport of maltose into the cell; maltose transporter permease complement(4222718..4223608) Escherichia fergusonii ATCC 35469 7122390 YP_002385138.1 CDS malF NC_011740.1 4223621 4225165 R with MalKGE is involved in maltose transport into the cell; maltose transporter membrane protein complement(4223621..4225165) Escherichia fergusonii ATCC 35469 7121223 YP_002385139.1 CDS malE NC_011740.1 4225319 4226509 R functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis; maltose ABC transporter periplasmic protein complement(4225319..4226509) Escherichia fergusonii ATCC 35469 7121222 YP_002385140.1 CDS malK NC_011740.1 4226887 4228002 D with malEFG is involved in import of maltose/maltodextrin; maltose/maltodextrin transporter ATP-binding protein 4226887..4228002 Escherichia fergusonii ATCC 35469 7123287 YP_002385141.1 CDS lamB NC_011740.1 4228077 4229417 D porin involved in the transport of maltose and maltodextrins; maltoporin 4228077..4229417 Escherichia fergusonii ATCC 35469 7121224 YP_002385142.1 CDS malM NC_011740.1 4229515 4230456 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87141162, 2434655, 6086106; Product type pt : transporter; maltose regulon periplasmic protein 4229515..4230456 Escherichia fergusonii ATCC 35469 7120817 YP_002385143.1 CDS ubiC NC_011740.1 4230469 4231131 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; chorismate pyruvate lyase 4230469..4231131 Escherichia fergusonii ATCC 35469 7121225 YP_002385144.1 CDS ubiA NC_011740.1 4231144 4232016 D catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway; 4-hydroxybenzoate octaprenyltransferase 4231144..4232016 Escherichia fergusonii ATCC 35469 7122617 YP_002385145.1 CDS plsB NC_011740.1 4232073 4234493 R PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA; glycerol-3-phosphate acyltransferase complement(4232073..4234493) Escherichia fergusonii ATCC 35469 7122615 YP_002385146.1 CDS dgkA NC_011740.1 4234664 4235032 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10220339, 6257698, 86278195, 88111690, 2984194, 6309817, 8071224; Product type e : enzyme; diacylglycerol kinase 4234664..4235032 Escherichia fergusonii ATCC 35469 7123642 YP_002385147.1 CDS lexA NC_011740.1 4235142 4235750 D Represses a number of genes involved in the response to DNA damage; LexA repressor 4235142..4235750 Escherichia fergusonii ATCC 35469 7122892 YP_002385148.1 CDS dinF NC_011740.1 4235823 4237148 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 87165788; Product type cp : cell process; DNA-damage-inducible SOS response protein 4235823..4237148 Escherichia fergusonii ATCC 35469 7120829 YP_002385149.1 CDS yjbJ NC_011740.1 4237280 4237489 D unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential; stress-response protein 4237280..4237489 Escherichia fergusonii ATCC 35469 7122898 YP_002385150.1 CDS zur NC_011740.1 4237540 4238055 R Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB; zinc uptake transcriptional repressor complement(4237540..4238055) Escherichia fergusonii ATCC 35469 7121872 YP_002385151.1 CDS yjbN NC_011740.1 4238220 4239215 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 22095566; Product type e : enzyme; tRNA-dihydrouridine synthase A 4238220..4239215 Escherichia fergusonii ATCC 35469 7122060 YP_002385152.1 CDS pspG NC_011740.1 4239350 4239592 D coordinately regulated along with pspA; PspF-dependent induction in response to secretin overexpression in Yersinia; phage shock protein G 4239350..4239592 Escherichia fergusonii ATCC 35469 7121873 YP_002385153.1 CDS qor NC_011740.1 4239767 4240750 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94089392, 7602590; Product type e : enzyme; quinone oxidoreductase complement(4239767..4240750) Escherichia fergusonii ATCC 35469 7121874 YP_002385154.1 CDS dnaB NC_011740.1 4241253 4242668 D unwinds double stranded DNA; replicative DNA helicase 4241253..4242668 Escherichia fergusonii ATCC 35469 7122339 YP_002385155.1 CDS EFER_4142 NC_011740.1 4242701 4243321 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4242701..4243321) Escherichia fergusonii ATCC 35469 7122908 YP_002385156.1 CDS alr NC_011740.1 4243388 4244467 D converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase 4243388..4244467 Escherichia fergusonii ATCC 35469 7123257 YP_002385157.1 CDS EFER_4144 NC_011740.1 4244490 4245044 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter 4244490..4245044 Escherichia fergusonii ATCC 35469 7122293 YP_002385158.1 CDS EFER_4145 NC_011740.1 4245020 4246054 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator 4245020..4246054 Escherichia fergusonii ATCC 35469 7121022 YP_002385159.1 CDS tyrB NC_011740.1 4246130 4247323 D catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate; aromatic amino acid aminotransferase 4246130..4247323 Escherichia fergusonii ATCC 35469 7121023 YP_002385160.1 CDS sucB NC_011740.1 4250268 4251422 D Evidence 2b : Function of strongly homologous gene; PubMedId : 10739245, 6376124; Product type e : enzyme; dihydrolipoamide succinyltransferase (E2 component) 4250268..4251422 Escherichia fergusonii ATCC 35469 7121953 YP_002385161.1 CDS EFER_4150 NC_011740.1 4251434 4252852 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; dihydrolipoyl dehydrogenase, E3 component (lpd-like) 4251434..4252852 Escherichia fergusonii ATCC 35469 7121954 YP_002385162.1 CDS sucC NC_011740.1 4252874 4254043 D Evidence 1b : Function experimentally demonstrated in the studied species; Product type e : enzyme; succinyl-CoA synthetase subunit beta 4252874..4254043 Escherichia fergusonii ATCC 35469 7123793 YP_002385163.1 CDS sucD NC_011740.1 4254056 4254928 D Evidence 1b : Function experimentally demonstrated in the studied species; Product type e : enzyme; succinyl-CoA synthetase subunit alpha 4254056..4254928 Escherichia fergusonii ATCC 35469 7121956 YP_002385164.1 CDS EFER_4153 NC_011740.1 4255134 4256639 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter membrane protein 4255134..4256639 Escherichia fergusonii ATCC 35469 7121958 YP_002385165.1 CDS EFER_4154 NC_011740.1 4256513 4257724 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; malate/L-lactate dehydrogenases 4256513..4257724 Escherichia fergusonii ATCC 35469 7121024 YP_002385166.1 CDS dctD NC_011740.1 4257713 4259071 R Evidence 2b : Function of strongly homologous gene; PubMedId : 3671068; Product type r : regulator; C4-dicarboxylate transport transcriptional regulator complement(4257713..4259071) Escherichia fergusonii ATCC 35469 7121025 YP_002385167.1 CDS EFER_4156 NC_011740.1 4259061 4260884 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2134335; Product type prc : receptor; C4-dicarboxylate transport sensor protein complement(4259061..4260884) Escherichia fergusonii ATCC 35469 7122874 YP_002385168.1 CDS aphA NC_011740.1 4261161 4261874 D Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity; acid phosphatase/phosphotransferase 4261161..4261874 Escherichia fergusonii ATCC 35469 7123794 YP_002385169.1 CDS yjbQ NC_011740.1 4261985 4262401 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11972052; hypothetical protein 4261985..4262401 Escherichia fergusonii ATCC 35469 7120522 YP_002385170.1 CDS yjbR NC_011740.1 4262405 4262761 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4262405..4262761 Escherichia fergusonii ATCC 35469 7123940 YP_002385171.1 CDS uvrA NC_011740.1 4262796 4265618 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A complement(4262796..4265618) Escherichia fergusonii ATCC 35469 7121875 YP_002385172.1 CDS ssb NC_011740.1 4265872 4266408 D binds to single stranded DNA and PriA helcase facilitate replication restart; single-stranded DNA-binding protein 4265872..4266408 Escherichia fergusonii ATCC 35469 7122645 YP_002385173.1 CDS yjcB NC_011740.1 4266507 4266839 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(4266507..4266839) Escherichia fergusonii ATCC 35469 7121942 YP_002385174.1 CDS soxS NC_011740.1 4267032 4267355 R regulates genes involved in response to oxidative stress; DNA-binding transcriptional regulator SoxS complement(4267032..4267355) Escherichia fergusonii ATCC 35469 7123389 YP_002385175.1 CDS soxR NC_011740.1 4267442 4267906 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 91210176, 91360349, 94139656, 9564045, 10207625, 12670967, 1653416, 1708380, 7673113, 8065907, 8306957, 8631739, 8969171, 9019397, 9092651, 9204707; Product type r : regulator; DNA-binding transcriptional dual regulator 4267442..4267906 Escherichia fergusonii ATCC 35469 7121801 YP_002385176.1 CDS yjcD NC_011740.1 4268485 4269834 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; permease 4268485..4269834 Escherichia fergusonii ATCC 35469 7121185 YP_002385177.1 CDS yjcE NC_011740.1 4269991 4271637 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 21557160, 11479290; Product type pt : transporter; cation/proton antiporter 4269991..4271637 Escherichia fergusonii ATCC 35469 7121876 YP_002385178.1 CDS phnA NC_011740.1 4271701 4272036 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 93328121, 9650256, 2155230; hypothetical protein complement(4271701..4272036) Escherichia fergusonii ATCC 35469 7122000 YP_002385179.1 CDS EFER_4168 NC_011740.1 4272450 4274750 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4272450..4274750 Escherichia fergusonii ATCC 35469 7122596 YP_002385180.1 CDS EFER_4169 NC_011740.1 4274740 4275582 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4274740..4275582 Escherichia fergusonii ATCC 35469 7121026 YP_002385181.1 CDS proP NC_011740.1 4275863 4277365 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10049386, 12525168, 92165733, 93132799, 9871325, 99376621, 8421314; Product type t : transporter; proline/glycine betaine transporter 4275863..4277365 Escherichia fergusonii ATCC 35469 7121027 YP_002385182.1 CDS basS NC_011740.1 4277470 4278612 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94110256, 8282725; Product type r : regulator; sensor protein BasS/PmrB complement(4277470..4278612) Escherichia fergusonii ATCC 35469 7120134 YP_002385183.1 CDS basR NC_011740.1 4278609 4279298 R response regulator in two-component regulatory system with BasS; DNA-binding transcriptional regulator BasR complement(4278609..4279298) Escherichia fergusonii ATCC 35469 7121645 YP_002385184.1 CDS eptA NC_011740.1 4279277 4280920 R with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division; cell division protein complement(4279277..4280920) Escherichia fergusonii ATCC 35469 7123356 YP_002385185.1 CDS adiY NC_011740.1 4281025 4281915 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : c; Product type r : regulator; DNA-binding transcriptional activator complement(4281025..4281915) Escherichia fergusonii ATCC 35469 7122959 YP_002385186.1 CDS yjdF NC_011740.1 4282321 4282947 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(4282321..4282947) Escherichia fergusonii ATCC 35469 7122276 YP_002385187.1 CDS fumB NC_011740.1 4283070 4284716 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 86142617, 88193096, 89255123, 2656658; Product type e : enzyme; anaerobic class I fumarate hydratase complement(4283070..4284716) Escherichia fergusonii ATCC 35469 7123962 YP_002385188.1 CDS dcuB NC_011740.1 4284794 4286134 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters; anaerobic C4-dicarboxylate transporter complement(4284794..4286134) Escherichia fergusonii ATCC 35469 7120154 YP_002385189.1 CDS dcuR NC_011740.1 4286696 4287418 R response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration; DNA-binding transcriptional activator DcuR complement(4286696..4287418) Escherichia fergusonii ATCC 35469 7124118 YP_002385190.1 CDS dcuS NC_011740.1 4287415 4289046 R C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; sensory histidine kinase DcuS complement(4287415..4289046) Escherichia fergusonii ATCC 35469 7122878 YP_002385191.1 CDS EFER_4180 NC_011740.1 4289081 4289230 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4289081..4289230) Escherichia fergusonii ATCC 35469 7122879 YP_002385192.1 CDS dmsA NC_011740.1 4289538 4291964 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme; anaerobic dimethyl sulfoxide reductase subunit A 4289538..4291964 Escherichia fergusonii ATCC 35469 7123795 YP_002385193.1 CDS EFER_4182 NC_011740.1 4291978 4292604 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14522592; Product type pc : carrier; anaerobic reductase subunit B 4291978..4292604 Escherichia fergusonii ATCC 35469 7123553 YP_002385194.1 CDS EFER_4183 NC_011740.1 4292597 4293373 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14522592; Product type pe : enzyme; anaerobic reductase subunit C 4292597..4293373 Escherichia fergusonii ATCC 35469 7121028 YP_002385195.1 CDS EFER_4184 NC_011740.1 4293377 4294024 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14522592, 11309116; Product type pf : factor; twin-argninine leader-binding protein for anaerobic dehydrogenase 4293377..4294024 Escherichia fergusonii ATCC 35469 7121029 YP_002385196.1 CDS EFER_4185 NC_011740.1 4293877 4294551 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; ferredoxin 4293877..4294551 Escherichia fergusonii ATCC 35469 7121030 YP_002385197.1 CDS yjdC NC_011740.1 4295656 4296231 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1370290; Product type pr : regulator; transcriptional regulator complement(4295656..4296231) Escherichia fergusonii ATCC 35469 7120051 YP_002385198.1 CDS dipZ NC_011740.1 4296268 4297962 R two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm; thiol:disulfide interchange protein complement(4296268..4297962) Escherichia fergusonii ATCC 35469 7123961 YP_002385199.1 CDS cutA NC_011740.1 4297938 4298282 R copper binding protein required for copper tolerance; involved in resistance toward heavy metals; divalent-cation tolerance protein CutA complement(4297938..4298282) Escherichia fergusonii ATCC 35469 7123552 YP_002385200.1 CDS dcuA NC_011740.1 4298392 4299693 R functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB; anaerobic C4-dicarboxylate transporter complement(4298392..4299693) Escherichia fergusonii ATCC 35469 7122832 YP_002385201.1 CDS aspA NC_011740.1 4299807 4301243 R catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase complement(4299807..4301243) Escherichia fergusonii ATCC 35469 7124117 YP_002385202.1 CDS fxsA NC_011740.1 4301580 4302056 D F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA protein 4301580..4302056 Escherichia fergusonii ATCC 35469 7120570 YP_002385203.1 CDS yjeH NC_011740.1 4302072 4303328 R uncharacterized member of the APC superfamily of amino acid transporters; unknown function; inner membrane protein YjeH complement(4302072..4303328) Escherichia fergusonii ATCC 35469 7120157 YP_002385204.1 CDS groES NC_011740.1 4303604 4303897 D 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 4303604..4303897 Escherichia fergusonii ATCC 35469 7122008 YP_002385205.1 CDS groEL NC_011740.1 4303941 4305587 D 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 4303941..4305587 Escherichia fergusonii ATCC 35469 7120616 YP_002385206.1 CDS yjeI NC_011740.1 4305722 4306075 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4305722..4306075 Escherichia fergusonii ATCC 35469 7120615 YP_002385207.1 CDS EFER_4197 NC_011740.1 4306129 4306995 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4306129..4306995) Escherichia fergusonii ATCC 35469 7122009 YP_002385208.1 CDS yjeK NC_011740.1 4307370 4308398 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 2019591, 10629195; Product type pe : enzyme; lysine aminomutase complement(4307370..4308398) Escherichia fergusonii ATCC 35469 7121032 YP_002385209.1 CDS efp NC_011740.1 4308440 4309006 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 4308440..4309006 Escherichia fergusonii ATCC 35469 7122010 YP_002385210.1 CDS ecnA NC_011740.1 4309058 4309183 D acts as and antidote to the bacteriolytic entericidin B in the EcnAB toxin-antitoxin complex; entericidin A 4309058..4309183 Escherichia fergusonii ATCC 35469 7122940 YP_002385211.1 CDS ecnB NC_011740.1 4309294 4309440 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 98344100, 9677290; Product type lp : lipoprotein; entericidin B membrane lipoprotein 4309294..4309440 Escherichia fergusonii ATCC 35469 7123558 YP_002385212.1 CDS sugE NC_011740.1 4309466 4309933 D Evidence 2b : Function of strongly homologous gene; PubMedId : 11948170; Product type t : transporter; large cation (quaternary ammonium) efflux transporter 4309466..4309933 Escherichia fergusonii ATCC 35469 7122934 YP_002385213.1 CDS blc NC_011740.1 4309930 4310463 R lipocalin; globomycin-sensitive outer membrane lipoprotein; outer membrane lipoprotein Blc complement(4309930..4310463) Escherichia fergusonii ATCC 35469 7121964 YP_002385214.1 CDS ampC NC_011740.1 4310552 4311685 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 92212899, 97464439, 99421326, 10595535, 6795623, 7041115, 9819201; Product type e : enzyme; beta-lactamase complement(4310552..4311685) Escherichia fergusonii ATCC 35469 7121675 YP_002385215.1 CDS frdD NC_011740.1 4311748 4312107 R in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane; fumarate reductase subunit D complement(4311748..4312107) Escherichia fergusonii ATCC 35469 7122791 YP_002385216.1 CDS frdC NC_011740.1 4312118 4312513 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase subunit C complement(4312118..4312513) Escherichia fergusonii ATCC 35469 7123011 YP_002385217.1 CDS frdB NC_011740.1 4312524 4313258 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase iron-sulfur subunit complement(4312524..4313258) Escherichia fergusonii ATCC 35469 7123010 YP_002385218.1 CDS frdA NC_011740.1 4313251 4315059 R part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; fumarate reductase flavoprotein subunit complement(4313251..4315059) Escherichia fergusonii ATCC 35469 7123009 YP_002385219.1 CDS poxA NC_011740.1 4315385 4316362 D lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 4315385..4316362 Escherichia fergusonii ATCC 35469 7124141 YP_002385220.1 CDS yjeM NC_011740.1 4316580 4318082 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; transporter 4316580..4318082 Escherichia fergusonii ATCC 35469 7123105 YP_002385221.1 CDS EFER_4211 NC_011740.1 4317980 4318183 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4317980..4318183 Escherichia fergusonii ATCC 35469 7123963 YP_002385222.1 CDS yjeO NC_011740.1 4318180 4318494 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 4318180..4318494 Escherichia fergusonii ATCC 35469 7121033 YP_002385223.1 CDS yjeP NC_011740.1 4318525 4321848 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; hypothetical protein complement(4318525..4321848) Escherichia fergusonii ATCC 35469 7122011 YP_002385224.1 CDS psd NC_011740.1 4321870 4322838 R catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase complement(4321870..4322838) Escherichia fergusonii ATCC 35469 7123409 YP_002385225.1 CDS rsgA NC_011740.1 4322935 4323987 R EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase complement(4322935..4323987) Escherichia fergusonii ATCC 35469 7124017 YP_002385226.1 CDS orn NC_011740.1 4324082 4324627 D 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 4324082..4324627 Escherichia fergusonii ATCC 35469 7121148 YP_002385227.1 CDS artJ NC_011740.1 4324667 4325482 R Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type f : factor; arginine-binding periplasmic protein 2 complement(4324667..4325482) Escherichia fergusonii ATCC 35469 7123579 YP_002385228.1 CDS yjeS NC_011740.1 4326260 4327399 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc : carrier; Fe-S electron transport protein complement(4326260..4327399) Escherichia fergusonii ATCC 35469 7120048 YP_002385229.1 CDS yjeF NC_011740.1 4327398 4328945 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 4327398..4328945 Escherichia fergusonii ATCC 35469 7123964 YP_002385230.1 CDS yjeE NC_011740.1 4328917 4329378 D possibly involved in cell wall synthesis; ATPase 4328917..4329378 Escherichia fergusonii ATCC 35469 7122007 YP_002385231.1 CDS amiB NC_011740.1 4329397 4330734 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 21348478, 87242501, 1594459, 7511774; Product type e : enzyme; N-acetylmuramoyl-l-alanine amidase II 4329397..4330734 Escherichia fergusonii ATCC 35469 7122006 YP_002385232.1 CDS mutL NC_011740.1 4330744 4332591 D This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 4330744..4332591 Escherichia fergusonii ATCC 35469 7122300 YP_002385233.1 CDS miaA NC_011740.1 4332584 4333534 D IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 4332584..4333534 Escherichia fergusonii ATCC 35469 7120653 YP_002385234.1 CDS hfq NC_011740.1 4333620 4333928 D Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 4333620..4333928 Escherichia fergusonii ATCC 35469 7120929 YP_002385235.1 CDS hflX NC_011740.1 4334004 4335284 D involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein; GTPase HflX 4334004..4335284 Escherichia fergusonii ATCC 35469 7122192 YP_002385236.1 CDS hflK NC_011740.1 4335370 4336629 D with HflC inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflK 4335370..4336629 Escherichia fergusonii ATCC 35469 7122191 YP_002385237.1 CDS hflC NC_011740.1 4336632 4337636 D with HflK inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflC 4336632..4337636 Escherichia fergusonii ATCC 35469 7122190 YP_002385238.1 CDS yjeT NC_011740.1 4337718 4337915 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 4337718..4337915 Escherichia fergusonii ATCC 35469 7122188 YP_002385239.1 CDS purA NC_011740.1 4338019 4339317 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 4338019..4339317 Escherichia fergusonii ATCC 35469 7122012 YP_002385240.1 CDS nsrR NC_011740.1 4339522 4339947 D negatively regulates the transcription of genes upregulated by nitrosative stress; transcriptional repressor NsrR 4339522..4339947 Escherichia fergusonii ATCC 35469 7122318 YP_002385241.1 CDS rnr NC_011740.1 4339986 4342427 D 3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs; exoribonuclease R 4339986..4342427 Escherichia fergusonii ATCC 35469 7119665 YP_002385242.1 CDS rlmB NC_011740.1 4342518 4343249 D Specifically methylates the ribose of guanosine 2251 in 23S rRNA; 23S rRNA (guanosine-2'-O-)-methyltransferase 4342518..4343249 Escherichia fergusonii ATCC 35469 7121431 YP_002385243.1 CDS yjfI NC_011740.1 4343376 4343771 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4343376..4343771 Escherichia fergusonii ATCC 35469 7123865 YP_002385244.1 CDS yjfJ NC_011740.1 4343790 4344488 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator effector protein 4343790..4344488 Escherichia fergusonii ATCC 35469 7122014 YP_002385245.1 CDS yjfK NC_011740.1 4344654 4345313 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4344654..4345313 Escherichia fergusonii ATCC 35469 7122015 YP_002385246.1 CDS yjfL NC_011740.1 4345331 4345729 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 4345331..4345729 Escherichia fergusonii ATCC 35469 7122016 YP_002385247.1 CDS EFER_4238 NC_011740.1 4345733 4346386 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4345733..4346386 Escherichia fergusonii ATCC 35469 7122017 YP_002385248.1 CDS yjfC NC_011740.1 4346389 4347552 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; synthetase/amidase 4346389..4347552 Escherichia fergusonii ATCC 35469 7121034 YP_002385249.1 CDS aidB NC_011740.1 4347618 4349261 D catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA; isovaleryl CoA dehydrogenase 4347618..4349261 Escherichia fergusonii ATCC 35469 7123410 YP_002385250.1 CDS yjfN NC_011740.1 4349404 4349724 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4349404..4349724) Escherichia fergusonii ATCC 35469 7122289 YP_002385251.1 CDS yjfO NC_011740.1 4349908 4350279 R in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility; biofilm stress and motility protein A complement(4349908..4350279) Escherichia fergusonii ATCC 35469 7122018 YP_002385252.1 CDS EFER_4243 NC_011740.1 4350463 4351212 D YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo; esterase 4350463..4351212 Escherichia fergusonii ATCC 35469 7123965 YP_002385253.1 CDS ulaR NC_011740.1 4351209 4351964 R negative regulator of ulaG and ulaABCDEF; transcriptional repressor UlaR complement(4351209..4351964) Escherichia fergusonii ATCC 35469 7121035 YP_002385254.1 CDS ulaG NC_011740.1 4352072 4353136 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12644495, 15808744; Product type pe : enzyme; L-ascorbate 6-phosphate lactonase complement(4352072..4353136) Escherichia fergusonii ATCC 35469 7124076 YP_002385255.1 CDS ulaA NC_011740.1 4353488 4354885 D membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC 4353488..4354885 Escherichia fergusonii ATCC 35469 7122636 YP_002385256.1 CDS ulaB NC_011740.1 4354901 4355206 D involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIB 4354901..4355206 Escherichia fergusonii ATCC 35469 7122631 YP_002385257.1 CDS ulaC NC_011740.1 4355216 4355680 D involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; PTS system L-ascorbate-specific transporter subunit IIA 4355216..4355680 Escherichia fergusonii ATCC 35469 7122632 YP_002385258.1 CDS ulaD NC_011740.1 4355694 4356344 D catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase 4355694..4356344 Escherichia fergusonii ATCC 35469 7122633 YP_002385259.1 CDS ulaE NC_011740.1 4356354 4357208 D UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway; L-xylulose 5-phosphate 3-epimerase 4356354..4357208 Escherichia fergusonii ATCC 35469 7122634 YP_002385260.1 CDS sgaE NC_011740.1 4357208 4357894 D catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 4357208..4357894 Escherichia fergusonii ATCC 35469 7124075 YP_002385261.1 CDS yjfY NC_011740.1 4358023 4358298 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4358023..4358298) Escherichia fergusonii ATCC 35469 7122635 YP_002385262.1 CDS rpsF NC_011740.1 4358626 4359021 D binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 4358626..4359021 Escherichia fergusonii ATCC 35469 7122019 YP_002385263.1 CDS priB NC_011740.1 4359028 4359342 D binds single-stranded DNA at the primosome assembly site; primosomal replication protein N 4359028..4359342 Escherichia fergusonii ATCC 35469 7121131 YP_002385264.1 CDS rpsR NC_011740.1 4359347 4359574 D binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 4359347..4359574 Escherichia fergusonii ATCC 35469 7120126 YP_002385265.1 CDS rplI NC_011740.1 4359616 4360065 D in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 4359616..4360065 Escherichia fergusonii ATCC 35469 7123814 YP_002385266.1 CDS EFER_4257 NC_011740.1 4360177 4361148 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; dicarboxylate-binding periplasmic protein complement(4360177..4361148) Escherichia fergusonii ATCC 35469 7123266 YP_002385267.1 CDS EFER_4258 NC_011740.1 4361201 4362502 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ATP-independent transporter subunit complement(4361201..4362502) Escherichia fergusonii ATCC 35469 7121036 YP_002385268.1 CDS EFER_4259 NC_011740.1 4362545 4363045 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; ATP-independent transporter subunit complement(4362545..4363045) Escherichia fergusonii ATCC 35469 7121037 YP_002385269.1 CDS EFER_4260 NC_011740.1 4363042 4365123 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; oxidoreductase complement(4363042..4365123) Escherichia fergusonii ATCC 35469 7121038 YP_002385270.1 CDS EFER_4261 NC_011740.1 4365120 4366661 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; CoA transferase complement(4365120..4366661) Escherichia fergusonii ATCC 35469 7120451 YP_002385271.1 CDS EFER_4262 NC_011740.1 4366671 4367447 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; acyl-CoA hydratase complement(4366671..4367447) Escherichia fergusonii ATCC 35469 7120453 YP_002385272.1 CDS EFER_4263 NC_011740.1 4367457 4368299 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein complement(4367457..4368299) Escherichia fergusonii ATCC 35469 7123162 YP_002385273.1 CDS EFER_4264 NC_011740.1 4368309 4369100 R catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(4368309..4369100) Escherichia fergusonii ATCC 35469 7123703 YP_002385274.1 CDS ytfA NC_011740.1 4369223 4369948 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator 4369223..4369948 Escherichia fergusonii ATCC 35469 7120454 YP_002385275.1 CDS ytfB NC_011740.1 4369949 4370611 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 8559074; Product type ps : structure; cell envelope opacity-associated protein complement(4369949..4370611) Escherichia fergusonii ATCC 35469 7123589 YP_002385276.1 CDS fklB NC_011740.1 4370797 4371417 D FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; peptidyl-prolyl cis-trans isomerase 4370797..4371417 Escherichia fergusonii ATCC 35469 7119758 YP_002385277.1 CDS cycA NC_011740.1 4371725 4373137 D involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine; D-alanine/D-serine/glycine permease 4371725..4373137 Escherichia fergusonii ATCC 35469 7120023 YP_002385278.1 CDS ytfE NC_011740.1 4373182 4373844 R Involved in anaerobic NO protection and iron metabolism; iron-sulfur cluster repair di-iron protein complement(4373182..4373844) Escherichia fergusonii ATCC 35469 7123541 YP_002385279.1 CDS ytfF NC_011740.1 4373952 4374926 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(4373952..4374926) Escherichia fergusonii ATCC 35469 7119759 YP_002385280.1 CDS ytfG NC_011740.1 4375026 4375886 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 14747727; Product type e : enzyme; NAD(P)H:quinone oxidoreductase complement(4375026..4375886) Escherichia fergusonii ATCC 35469 7119760 YP_002385281.1 CDS ytfH NC_011740.1 4375975 4376355 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 20088838; Product type pr : regulator; transcriptional regulator 4375975..4376355 Escherichia fergusonii ATCC 35469 7119761 YP_002385282.1 CDS cpdB NC_011740.1 4376484 4378427 R periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein complement(4376484..4378427) Escherichia fergusonii ATCC 35469 7123045 YP_002385283.1 CDS cysQ NC_011740.1 4378616 4379356 D catalyzes the formation of AMP from adenosine-3',5'-bisphosphate; adenosine-3'(2'),5'-bisphosphate nucleotidase 4378616..4379356 Escherichia fergusonii ATCC 35469 7122795 YP_002385284.1 CDS ytfJ NC_011740.1 4379346 4379903 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9298646; Product type pr : regulator; transcriptional regulator complement(4379346..4379903) Escherichia fergusonii ATCC 35469 7122855 YP_002385285.1 CDS ytfK NC_011740.1 4380228 4380434 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4380228..4380434 Escherichia fergusonii ATCC 35469 7123590 YP_002385286.1 CDS ytfL NC_011740.1 4380495 4381838 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(4380495..4381838) Escherichia fergusonii ATCC 35469 7119762 YP_002385287.1 CDS EFER_4278 NC_011740.1 4382091 4382501 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; hypothetical protein 4382091..4382501 Escherichia fergusonii ATCC 35469 7123046 YP_002385288.1 CDS EFER_4279 NC_011740.1 4382581 4382910 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4382581..4382910) Escherichia fergusonii ATCC 35469 7120455 YP_002385289.1 CDS rpiB NC_011740.1 4382978 4383427 R catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B complement(4382978..4383427) Escherichia fergusonii ATCC 35469 7120456 YP_002385290.1 CDS rpiR NC_011740.1 4383788 4384678 D involved in rpiB and als operon repression; DNA-binding transcriptional repressor RpiR 4383788..4384678 Escherichia fergusonii ATCC 35469 7121436 YP_002385291.1 CDS alsB NC_011740.1 4384735 4385670 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20026827, 9401019, 10064713, 8576032; Product type t : transporter; D-allose transporter subunit 4384735..4385670 Escherichia fergusonii ATCC 35469 7121437 YP_002385292.1 CDS alsA NC_011740.1 4385731 4387263 D with AlsBC acts to import allose into the cell; AlsA contain 2 ATP-binding domains; D-allose transporter ATP-binding protein 4385731..4387263 Escherichia fergusonii ATCC 35469 7122295 YP_002385293.1 CDS alsC NC_011740.1 4387242 4388222 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20026827, 9401019; Product type t : transporter; D-allose transporter subunit 4387242..4388222 Escherichia fergusonii ATCC 35469 7122294 YP_002385294.1 CDS alsE NC_011740.1 4388233 4388919 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20026827, 9401019; Product type e : enzyme; allulose-6-phosphate 3-epimerase 4388233..4388919 Escherichia fergusonii ATCC 35469 7122296 YP_002385295.1 CDS alsK NC_011740.1 4388888 4389826 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9401019; Product type e : enzyme; D-allose kinase 4388888..4389826 Escherichia fergusonii ATCC 35469 7122297 YP_002385296.1 CDS yjcS NC_011740.1 4390054 4392057 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 1587481; Product type pe : enzyme; alkyl sulfatase 4390054..4392057 Escherichia fergusonii ATCC 35469 7122298 YP_002385297.1 CDS EFER_4288 NC_011740.1 4392222 4392539 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4392222..4392539 Escherichia fergusonii ATCC 35469 7122004 YP_002385298.1 CDS yjcR NC_011740.1 4392560 4393591 D with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug resistance protein MdtN 4392560..4393591 Escherichia fergusonii ATCC 35469 7120457 YP_002385299.1 CDS EFER_4290 NC_011740.1 4393591 4395597 D possibly part of a tripartite efflux system composed of MdtN, MdtO and MdtP which could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride; multidrug efflux system protein MdtO 4393591..4395597 Escherichia fergusonii ATCC 35469 7122003 YP_002385300.1 CDS yjcP NC_011740.1 4395594 4397051 D part of a multidrug efflux system involved in resistance to acriflavin, puromycin, erytjhromycin and tetraphenylarsonium chloride; member of the outer membrane factor (OMF) family; outer membrane efflux protein MdtP 4395594..4397051 Escherichia fergusonii ATCC 35469 7123704 YP_002385301.1 CDS fdhF NC_011740.1 4397249 4399396 D Evidence 1c : Function experimentally demonstrated in the studied genus; Product type e : enzyme; formate dehydrogenase-H, selenopolypeptide subunit 4397249..4399396 Escherichia fergusonii ATCC 35469 7122002 YP_002385302.1 CDS yjcO NC_011740.1 4399487 4400176 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4399487..4400176 Escherichia fergusonii ATCC 35469 7123086 YP_002385303.1 CDS gltP NC_011740.1 4400250 4401746 R carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system; glutamate/aspartate:proton symporter complement(4400250..4401746) Escherichia fergusonii ATCC 35469 7122001 YP_002385304.1 CDS acs NC_011740.1 4402212 4404170 D Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 4402212..4404170 Escherichia fergusonii ATCC 35469 7123722 YP_002385305.1 CDS EFER_4297 NC_011740.1 4404231 4404710 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4404231..4404710 Escherichia fergusonii ATCC 35469 7124010 YP_002385306.1 CDS actP NC_011740.1 4404707 4406356 D member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake; acetate permease 4404707..4406356 Escherichia fergusonii ATCC 35469 7120458 YP_002385307.1 CDS msrA NC_011740.1 4406397 4407035 R this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A complement(4406397..4407035) Escherichia fergusonii ATCC 35469 7124011 YP_002385308.1 CDS ytfM NC_011740.1 4407241 4408974 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 4407241..4408974 Escherichia fergusonii ATCC 35469 7120973 YP_002385309.1 CDS ytfN NC_011740.1 4408971 4412747 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4408971..4412747 Escherichia fergusonii ATCC 35469 7119763 YP_002385310.1 CDS ytfP NC_011740.1 4412750 4413091 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4412750..4413091 Escherichia fergusonii ATCC 35469 7119764 YP_002385311.1 CDS EFER_4303 NC_011740.1 4413241 4414713 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4413241..4414713 Escherichia fergusonii ATCC 35469 7119765 YP_002385312.1 CDS insG NC_011740.1 4414786 4416114 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; IS4 transposase; KpLE2 phage-like element complement(4414786..4416114) Escherichia fergusonii ATCC 35469 7120459 YP_002385313.1 CDS ppa NC_011740.1 4416564 4417094 R catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase complement(4416564..4417094) Escherichia fergusonii ATCC 35469 7120746 YP_002385314.1 CDS ytfQ NC_011740.1 4417404 4418360 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 9298646; Product type pt : transporter; sugar ABC transporter periplasmic-binding protein 4417404..4418360 Escherichia fergusonii ATCC 35469 7120106 YP_002385315.1 CDS ytfR NC_011740.1 4418493 4419995 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; sugar ABC transporter ATP-binding protein 4418493..4419995 Escherichia fergusonii ATCC 35469 7119766 YP_002385316.1 CDS ytfT NC_011740.1 4420009 4421031 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; sugar ABC transporter membrane protein 4420009..4421031 Escherichia fergusonii ATCC 35469 7119767 YP_002385317.1 CDS yjfF NC_011740.1 4421018 4422013 D membrane component of a sugar ABC transporter system; inner membrane ABC transporter permease YjfF 4421018..4422013 Escherichia fergusonii ATCC 35469 7119768 YP_002385318.1 CDS fbp NC_011740.1 4422046 4423044 R catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase complement(4422046..4423044) Escherichia fergusonii ATCC 35469 7122013 YP_002385319.1 CDS mpl NC_011740.1 4423220 4424593 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 96404780, 2843822, 7984428, 8808921; Product type e : enzyme; UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 4423220..4424593 Escherichia fergusonii ATCC 35469 7123085 YP_002385320.1 CDS yjgA NC_011740.1 4424676 4425227 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4424676..4425227) Escherichia fergusonii ATCC 35469 7120959 YP_002385321.1 CDS pmbA NC_011740.1 4425321 4426673 D protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD; peptidase PmbA 4425321..4426673 Escherichia fergusonii ATCC 35469 7123411 YP_002385322.1 CDS cybC NC_011740.1 4426726 4427112 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1761034, 8499452, 10393541; Product type c : carrier; soluble cytochrome b562 4426726..4427112 Escherichia fergusonii ATCC 35469 7120090 YP_002385323.1 CDS EFER_4315 NC_011740.1 4427109 4427255 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4427109..4427255) Escherichia fergusonii ATCC 35469 7122838 YP_002385324.1 CDS EFER_4316 NC_011740.1 4427303 4427545 D Qin prophage; bifunctional antitoxin of the RelE-RelB toxin-antitoxin system/transcriptional repressor; bifunctional antitoxin/transcriptional repressor RelB 4427303..4427545 Escherichia fergusonii ATCC 35469 7123163 YP_002385325.1 CDS EFER_4317 NC_011740.1 4427457 4427831 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9767574, 11274135, 11717402, 12526800, 15576765; Product type f : factor; RelE protein; cytotoxic translational repressor of toxin-antitoxin stability system 4427457..4427831 Escherichia fergusonii ATCC 35469 7120460 YP_002385326.1 CDS nrdG NC_011740.1 4427828 4428292 R activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; anaerobic ribonucleotide reductase-activating protein complement(4427828..4428292) Escherichia fergusonii ATCC 35469 7120461 YP_002385327.1 CDS EFER_4319 NC_011740.1 4427945 4428436 D Evidence 6 : Doubtful CDS; hypothetical protein 4427945..4428436 Escherichia fergusonii ATCC 35469 7119662 YP_002385328.1 CDS nrdD NC_011740.1 4428450 4430588 R Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase complement(4428450..4430588) Escherichia fergusonii ATCC 35469 7123164 YP_002385329.1 CDS treC NC_011740.1 4430982 4432637 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90264345, 93302496, 8083158, 8421692; Product type e : enzyme; trehalose-6-phosphate hydrolase complement(4430982..4432637) Escherichia fergusonii ATCC 35469 7123027 YP_002385330.1 CDS treB NC_011740.1 4432688 4434109 R phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system trehalose(maltose)-specific transporter subunit IIBC complement(4432688..4434109) Escherichia fergusonii ATCC 35469 7122155 YP_002385331.1 CDS treR NC_011740.1 4434228 4435175 R regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon; trehalose repressor complement(4434228..4435175) Escherichia fergusonii ATCC 35469 7122154 YP_002385332.1 CDS EFER_4324 NC_011740.1 4435298 4435759 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4435298..4435759) Escherichia fergusonii ATCC 35469 7123433 YP_002385333.1 CDS yjgF NC_011740.1 4435819 4436205 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12515541, 10493123, 10595546, 9298646; Product type pe : enzyme; ketoacid-binding protein complement(4435819..4436205) Escherichia fergusonii ATCC 35469 7120462 YP_002385334.1 CDS pyrI NC_011740.1 4436277 4436738 R involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase regulatory subunit complement(4436277..4436738) Escherichia fergusonii ATCC 35469 7123412 YP_002385335.1 CDS pyrB NC_011740.1 4436751 4437686 R catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit complement(4436751..4437686) Escherichia fergusonii ATCC 35469 7122338 YP_002385336.1 CDS EFER_4328 NC_011740.1 4437913 4438452 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; arginine repressor complement(4437913..4438452) Escherichia fergusonii ATCC 35469 7122333 YP_002385337.1 CDS EFER_4329 NC_011740.1 4438527 4439963 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4438527..4439963) Escherichia fergusonii ATCC 35469 7120463 YP_002385338.1 CDS arcB NC_011740.1 4439987 4441018 R catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase complement(4439987..4441018) Escherichia fergusonii ATCC 35469 7120464 YP_002385339.1 CDS arcC NC_011740.1 4441015 4441971 R reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase complement(4441015..4441971) Escherichia fergusonii ATCC 35469 7120534 YP_002385340.1 CDS EFER_4332 NC_011740.1 4441958 4443181 R catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase complement(4441958..4443181) Escherichia fergusonii ATCC 35469 7120535 YP_002385341.1 CDS yjgK NC_011740.1 4443855 4444307 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11115104; hypothetical protein 4443855..4444307 Escherichia fergusonii ATCC 35469 7120465 YP_002385342.1 CDS argI NC_011740.1 4444352 4445374 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 90133956, 90153882, 90368679, 3072022, 6369246, 9253409, 9275160, 9298646, 6577418; Product type e : enzyme; ornithine carbamoyltransferase 1 complement(4444352..4445374) Escherichia fergusonii ATCC 35469 7122021 YP_002385343.1 CDS yjgD NC_011740.1 4445519 4445935 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4445519..4445935 Escherichia fergusonii ATCC 35469 7120540 YP_002385344.1 CDS yjgM NC_011740.1 4445982 4446497 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; acetyltransferase complement(4445982..4446497) Escherichia fergusonii ATCC 35469 7122020 YP_002385345.1 CDS EFER_4338 NC_011740.1 4446562 4447833 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4446562..4447833 Escherichia fergusonii ATCC 35469 7122022 YP_002385346.1 CDS valS NC_011740.1 4447892 4450747 R valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase complement(4447892..4450747) Escherichia fergusonii ATCC 35469 7120466 YP_002385347.1 CDS holC NC_011740.1 4450747 4451190 R binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi complement(4450747..4451190) Escherichia fergusonii ATCC 35469 7122656 YP_002385348.1 CDS EFER_4341 NC_011740.1 4451256 4451672 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4451256..4451672) Escherichia fergusonii ATCC 35469 7122210 YP_002385349.1 CDS pepA NC_011740.1 4451693 4453204 R catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase complement(4451693..4453204) Escherichia fergusonii ATCC 35469 7123705 YP_002385350.1 CDS yjgP NC_011740.1 4453471 4454571 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 4453471..4454571 Escherichia fergusonii ATCC 35469 7122574 YP_002385351.1 CDS yjgQ NC_011740.1 4454571 4455653 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 4454571..4455653 Escherichia fergusonii ATCC 35469 7122023 YP_002385352.1 CDS ecfH NC_011740.1 4455797 4456372 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 11274153; hypothetical protein complement(4455797..4456372) Escherichia fergusonii ATCC 35469 7122024 YP_002385353.1 CDS yraO NC_011740.1 4456382 4456972 R Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein; DnaA initiator-associating protein DiaA complement(4456382..4456972) Escherichia fergusonii ATCC 35469 7122933 YP_002385354.1 CDS yraN NC_011740.1 4456992 4457387 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4456992..4457387) Escherichia fergusonii ATCC 35469 7123041 YP_002385355.1 CDS yraM NC_011740.1 4457345 4459381 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4457345..4459381) Escherichia fergusonii ATCC 35469 7119741 YP_002385356.1 CDS yraL NC_011740.1 4459446 4460309 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; methyltransferase 4459446..4460309 Escherichia fergusonii ATCC 35469 7123040 YP_002385357.1 CDS agaI NC_011740.1 4460359 4461126 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10931310; Product type e : enzyme; galactosamine-6-phosphate isomerase complement(4460359..4461126) Escherichia fergusonii ATCC 35469 7123039 YP_002385358.1 CDS agaD NC_011740.1 4461127 4461918 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IID complement(4461127..4461918) Escherichia fergusonii ATCC 35469 7124012 YP_002385359.1 CDS agaC NC_011740.1 4461908 4462711 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane;protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIC complement(4461908..4462711) Escherichia fergusonii ATCC 35469 7122284 YP_002385360.1 CDS agaB NC_011740.1 4462750 4463226 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB complement(4462750..4463226) Escherichia fergusonii ATCC 35469 7122283 YP_002385361.1 CDS kbaY NC_011740.1 4463392 4464252 R catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway; tagatose-bisphosphate aldolase complement(4463392..4464252) Escherichia fergusonii ATCC 35469 7122282 YP_002385362.1 CDS agaS NC_011740.1 4464265 4465419 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9689210, 9697096, 14731281, 8932697; Product type e : enzyme; tagatose-6-phosphate ketose/aldose isomerase complement(4464265..4465419) Escherichia fergusonii ATCC 35469 7120801 YP_002385363.1 CDS agaA NC_011740.1 4465770 4466924 R Evidence 2b : Function of strongly homologous gene; Product type e : enzyme; N-acetylglucosamine-6-phosphate deacetylase complement(4465770..4466924) Escherichia fergusonii ATCC 35469 7122286 YP_002385364.1 CDS EFER_4357 NC_011740.1 4466900 4467334 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; PTS system N-acetyl-galactosamine / galactosamine transporter subunit IIA complement(4466900..4467334) Escherichia fergusonii ATCC 35469 7122281 YP_002385365.1 CDS EFER_4358 NC_011740.1 4467352 4468236 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; PTS system hexose/hexosamine family transporter permease IID complement(4467352..4468236) Escherichia fergusonii ATCC 35469 7120467 YP_002385366.1 CDS EFER_4359 NC_011740.1 4468220 4468999 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter; PTS system transporter subunit IIC complement(4468220..4468999) Escherichia fergusonii ATCC 35469 7120468 YP_002385367.1 CDS agaV NC_011740.1 4469010 4469483 R catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake;involved in N-acetylgalactosamine transport; PTS system N-acetylgalactosamine-specific transporter subunit IIB complement(4469010..4469483) Escherichia fergusonii ATCC 35469 7120469 YP_002385368.1 CDS kbaZ NC_011740.1 4469506 4470786 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11976750, 20392444, 10931310, 8932697; Product type e : enzyme; tagatose 6-phosphate aldolase 1, kbaZ subunit complement(4469506..4470786) Escherichia fergusonii ATCC 35469 7122287 YP_002385369.1 CDS agaR NC_011740.1 4471034 4471843 D transcriptional repressor for the agaZVWA and agaSYBCDI operons; DNA-binding transcriptional regulator AgaR 4471034..4471843 Escherichia fergusonii ATCC 35469 7123756 YP_002385370.1 CDS yhaV NC_011740.1 4471898 4472362 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4471898..4472362) Escherichia fergusonii ATCC 35469 7122285 YP_002385371.1 CDS sohA NC_011740.1 4472362 4472697 R SohA; PrlF; involved in protein secretion; when overproduced or mutated, it induces growth defect and increased export of a reporter protein; a PrlF mutation induces the activity of the Lon protease, and a Lon-deficient strain suppresses the phenotype conferred by the PrlF mutation; regulator PrlF complement(4472362..4472697) Escherichia fergusonii ATCC 35469 7119879 YP_002385372.1 CDS garD NC_011740.1 4472846 4474417 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20225875, 66096392, 81027430, 9772162, 10762278, 2407727; Product type e : enzyme; (D)-galactarate dehydrogenase complement(4472846..4474417) Escherichia fergusonii ATCC 35469 7123377 YP_002385373.1 CDS garL NC_011740.1 4474888 4475658 D cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate; alpha-dehydro-beta-deoxy-D-glucarate aldolase 4474888..4475658 Escherichia fergusonii ATCC 35469 7123116 YP_002385374.1 CDS garR NC_011740.1 4475683 4476573 D catalyzes the reduction of tartronate semialdehyde to glycerate; tartronate semialdehyde reductase 4475683..4476573 Escherichia fergusonii ATCC 35469 7120174 YP_002385375.1 CDS EFER_4368 NC_011740.1 4476668 4476874 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(4476668..4476874) Escherichia fergusonii ATCC 35469 7120175 YP_002385376.1 CDS EFER_4369 NC_011740.1 4477289 4477990 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 15951572, 16411777, 15102328; Product type pe : enzyme; pirin-related protein YhaK complement(4477289..4477990) Escherichia fergusonii ATCC 35469 7121430 YP_002385377.1 CDS yhaJ NC_011740.1 4478095 4478991 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator 4478095..4478991 Escherichia fergusonii ATCC 35469 7123165 YP_002385378.1 CDS yhaH NC_011740.1 4479025 4479414 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(4479025..4479414) Escherichia fergusonii ATCC 35469 7119877 YP_002385379.1 CDS yqjG NC_011740.1 4479517 4480503 R Evidence 2b : Function of strongly homologous gene; PubMedId : 8478329; Product type e : enzyme; S-transferase complement(4479517..4480503) Escherichia fergusonii ATCC 35469 7119876 YP_002385380.1 CDS yqjF NC_011740.1 4480573 4480965 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; quinol oxidase subunit complement(4480573..4480965) Escherichia fergusonii ATCC 35469 7119738 YP_002385381.1 CDS yqjK NC_011740.1 4481152 4481451 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4481152..4481451) Escherichia fergusonii ATCC 35469 7119737 YP_002385382.1 CDS yqjE NC_011740.1 4481441 4481845 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(4481441..4481845) Escherichia fergusonii ATCC 35469 7119740 YP_002385383.1 CDS yqjD NC_011740.1 4481848 4482153 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4481848..4482153) Escherichia fergusonii ATCC 35469 7119736 YP_002385384.1 CDS EFER_4377 NC_011740.1 4482191 4482676 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4482191..4482676) Escherichia fergusonii ATCC 35469 7119735 YP_002385385.1 CDS EFER_4378 NC_011740.1 4482707 4483090 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4482707..4483090) Escherichia fergusonii ATCC 35469 7120471 YP_002385386.1 CDS yqjA NC_011740.1 4483094 4483756 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(4483094..4483756) Escherichia fergusonii ATCC 35469 7120472 YP_002385387.1 CDS EFER_4380 NC_011740.1 4483707 4483853 R Evidence 6 : Doubtful CDS; hypothetical protein complement(4483707..4483853) Escherichia fergusonii ATCC 35469 7119734 YP_002385388.1 CDS exuR NC_011740.1 4484102 4484878 R regulates the exuT, uxaCA and uxuRAB operons which encode genes involved in hexuronate utilization.; DNA-binding transcriptional repressor ExuR complement(4484102..4484878) Escherichia fergusonii ATCC 35469 7120473 YP_002385389.1 CDS exuT NC_011740.1 4485003 4486313 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 83218546, 98190790; Product type t : transporter; hexuronate transporter complement(4485003..4486313) Escherichia fergusonii ATCC 35469 7119977 YP_002385390.1 CDS uxaC NC_011740.1 4486773 4488185 D catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase 4486773..4488185 Escherichia fergusonii ATCC 35469 7123083 YP_002385391.1 CDS uxaA NC_011740.1 4488200 4489687 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 4570160, 83114543, 3038546; Product type e : enzyme; altronate hydrolase 4488200..4489687 Escherichia fergusonii ATCC 35469 7122651 YP_002385392.1 CDS ygjV NC_011740.1 4489764 4490330 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein 4489764..4490330 Escherichia fergusonii ATCC 35469 7122650 YP_002385393.1 CDS sstT NC_011740.1 4490334 4491578 R involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT complement(4490334..4491578) Escherichia fergusonii ATCC 35469 7123065 YP_002385394.1 CDS alx NC_011740.1 4491786 4492754 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 12107143, 2108134; Product type pm : membrane component; hypothetical protein complement(4491786..4492754) Escherichia fergusonii ATCC 35469 7121946 YP_002385395.1 CDS ygjR NC_011740.1 4493037 4494041 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; NAD(P)-binding dehydrogenase complement(4493037..4494041) Escherichia fergusonii ATCC 35469 7121939 YP_002385396.1 CDS ygjP NC_011740.1 4494878 4495381 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; metal dependent hydrolase complement(4494878..4495381) Escherichia fergusonii ATCC 35469 7119874 YP_002385397.1 CDS ygjO NC_011740.1 4495466 4496602 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; methyltransferase small domain 4495466..4496602 Escherichia fergusonii ATCC 35469 7123064 YP_002385398.1 CDS EFER_4395 NC_011740.1 4496735 4497553 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 4496735..4497553 Escherichia fergusonii ATCC 35469 7119872 YP_002385399.1 CDS mdoB NC_011740.1 4497637 4499928 R catalyzes the transfer of phosphoglycerol to the glucan backbone; phosphoglycerol transferase I complement(4497637..4499928) Escherichia fergusonii ATCC 35469 7120474 YP_002385400.1 CDS yjjA NC_011740.1 4500182 4500676 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4500182..4500676) Escherichia fergusonii ATCC 35469 7121243 YP_002385401.1 CDS dnaC NC_011740.1 4500727 4501464 R acts to load the DnaB helicase onto the initiation site during DNA replication; DNA replication protein DnaC complement(4500727..4501464) Escherichia fergusonii ATCC 35469 7122035 YP_002385402.1 CDS dnaT NC_011740.1 4501467 4502018 R This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'; primosomal protein DnaI complement(4501467..4502018) Escherichia fergusonii ATCC 35469 7122909 YP_002385403.2 CDS EFER_4400 NC_011740.1 4502114 4502587 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4502114..4502587) Escherichia fergusonii ATCC 35469 7124125 YP_002385404.1 CDS yjjP NC_011740.1 4502578 4503354 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type pm : membrane component; hypothetical protein complement(4502578..4503354) Escherichia fergusonii ATCC 35469 7120475 YP_002385405.1 CDS EFER_4403 NC_011740.1 4503641 4504828 D catalyzes the formation of protocatechuate from 4-hydroxybenzoate; 4-hydroxybenzoate 3-monooxygenase 4503641..4504828 Escherichia fergusonii ATCC 35469 7122039 YP_002385406.1 CDS EFER_4404 NC_011740.1 4504785 4505738 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; transcriptional regulator 4504785..4505738 Escherichia fergusonii ATCC 35469 7123706 YP_002385407.1 CDS EFER_4405 NC_011740.1 4505956 4506681 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : regulator; DNA-binding transcriptional regulator YjjQ12 4505956..4506681 Escherichia fergusonii ATCC 35469 7120476 YP_002385408.1 CDS EFER_4406 NC_011740.1 4506639 4507310 D regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin; DNA-binding transcriptional activator BglJ 4506639..4507310 Escherichia fergusonii ATCC 35469 7120477 YP_002385409.1 CDS fhuF NC_011740.1 4507370 4508158 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 11931550, 14756576, 3323834, 9990318; Product type c : carrier; ferric hydroximate transport ferric iron reductase complement(4507370..4508158) Escherichia fergusonii ATCC 35469 7120478 YP_002385410.1 CDS yjjZ NC_011740.1 4508299 4508535 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4508299..4508535 Escherichia fergusonii ATCC 35469 7120016 YP_002385411.1 CDS EFER_4411 NC_011740.1 4509330 4509749 R Evidence 5 : No homology to any previously reported sequences; PubMedId : 15849754; hypothetical protein complement(4509330..4509749) Escherichia fergusonii ATCC 35469 7123635 YP_002385412.1 CDS rsmC NC_011740.1 4510163 4511194 R 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit; 16S ribosomal RNA m2G1207 methyltransferase complement(4510163..4511194) Escherichia fergusonii ATCC 35469 7120479 YP_002385413.1 CDS holD NC_011740.1 4511297 4511710 D with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit psi 4511297..4511710 Escherichia fergusonii ATCC 35469 7121150 YP_002385414.1 CDS rimI NC_011740.1 4511679 4512125 D alanine acetyltransferase that specifically acetylates ribosomal protein S18; ribosomal-protein-alanine N-acetyltransferase 4511679..4512125 Escherichia fergusonii ATCC 35469 7122211 YP_002385415.1 CDS yjjG NC_011740.1 4512140 4512817 D manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily; nucleotidase 4512140..4512817 Escherichia fergusonii ATCC 35469 7123863 YP_002385416.1 CDS EFER_4416 NC_011740.1 4513203 4514426 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; integrase 4513203..4514426 Escherichia fergusonii ATCC 35469 7122036 YP_002385417.1 CDS flxA NC_011740.1 4514687 4515019 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 9358034; Product type h : extrachromosomal origin; hypothetical protein complement(4514687..4515019) Escherichia fergusonii ATCC 35469 7120480 YP_002385418.1 CDS yfdR NC_011740.1 4515732 4516268 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(4515732..4516268) Escherichia fergusonii ATCC 35469 7122998 YP_002385419.1 CDS yfdQ NC_011740.1 4516397 4517221 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein complement(4516397..4517221) Escherichia fergusonii ATCC 35469 7119836 YP_002385420.1 CDS EFER_4420 NC_011740.1 4517287 4517967 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4517287..4517967) Escherichia fergusonii ATCC 35469 7119834 YP_002385421.1 CDS EFER_4421 NC_011740.1 4517747 4518034 R Evidence 6 : Doubtful CDS; Product type h : extrachromosomal origin; hypothetical protein complement(4517747..4518034) Escherichia fergusonii ATCC 35469 7123166 YP_002385422.1 CDS EFER_4422 NC_011740.1 4517855 4518634 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 4517855..4518634 Escherichia fergusonii ATCC 35469 7120481 YP_002385423.1 CDS cII NC_011740.1 4518862 4519488 R Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Repressor protein C2 complement(4518862..4519488) Escherichia fergusonii ATCC 35469 7123167 YP_002385424.1 CDS EFER_4424 NC_011740.1 4519587 4519787 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; repressor protein dicC 4519587..4519787 Escherichia fergusonii ATCC 35469 7120893 YP_002385425.1 CDS ymfL NC_011740.1 4519711 4520376 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; nucleic acid-binding protein; e14 prophage 4519711..4520376 Escherichia fergusonii ATCC 35469 7120482 YP_002385426.1 CDS ymfM NC_011740.1 4520373 4520711 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 4520373..4520711 Escherichia fergusonii ATCC 35469 7122057 YP_002385427.1 CDS EFER_4428 NC_011740.1 4520721 4521662 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; phage replication protein O 4520721..4521662 Escherichia fergusonii ATCC 35469 7122059 YP_002385428.1 CDS yfdN NC_011740.1 4521659 4522153 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 4521659..4522153 Escherichia fergusonii ATCC 35469 7120483 YP_002385429.1 CDS EFER_4430 NC_011740.1 4522120 4522479 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 4522120..4522479 Escherichia fergusonii ATCC 35469 7119833 YP_002385430.1 CDS rusA NC_011740.1 4522476 4522865 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Crossover junction endodeoxyribonuclease 4522476..4522865 Escherichia fergusonii ATCC 35469 7123168 YP_002385431.1 CDS EFER_4432 NC_011740.1 4522885 4523682 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 4522885..4523682 Escherichia fergusonii ATCC 35469 7121167 YP_002385432.1 CDS EFER_4433 NC_011740.1 4523684 4524679 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4523684..4524679 Escherichia fergusonii ATCC 35469 7123707 YP_002385433.1 CDS ydfT NC_011740.1 4524693 4525445 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; antitermination protein Q; Qin prophage 4524693..4525445 Escherichia fergusonii ATCC 35469 7120484 YP_002385434.1 CDS cspF NC_011740.1 4525861 4526073 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9484881, 8022261, 9439003; Product type h : extrachromosomal origin; cold shock protein; Qin prophage complement(4525861..4526073) Escherichia fergusonii ATCC 35469 7122698 YP_002385435.1 CDS cspB NC_011740.1 4526376 4526591 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 94293754, 94293756, 9439003; Product type h : extrachromosomal origin; cold shock protein; Qin prophage 4526376..4526591 Escherichia fergusonii ATCC 35469 7123538 YP_002385436.1 CDS essQ NC_011740.1 4527344 4527559 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; S lysis protein; Qin prophage 4527344..4527559 Escherichia fergusonii ATCC 35469 7122818 YP_002385437.1 CDS EFER_4438 NC_011740.1 4527543 4528115 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 4527543..4528115 Escherichia fergusonii ATCC 35469 7119965 YP_002385438.1 CDS ydfQ NC_011740.1 4528437 4528970 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; membrane-associated lysozyme; Qin prophage 4528437..4528970 Escherichia fergusonii ATCC 35469 7120486 YP_002385439.1 CDS ydfP NC_011740.1 4528967 4529464 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 4528967..4529464 Escherichia fergusonii ATCC 35469 7123520 YP_002385440.1 CDS cspI NC_011740.1 4529828 4530040 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 9484881; Product type h : extrachromosomal origin; cold shock protein; Qin prophage 4529828..4530040 Escherichia fergusonii ATCC 35469 7124090 YP_002385441.1 CDS ynfN NC_011740.1 4530386 4530541 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 4530386..4530541 Escherichia fergusonii ATCC 35469 7122822 YP_002385442.1 CDS EFER_4444 NC_011740.1 4530621 4530887 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4530621..4530887 Escherichia fergusonii ATCC 35469 7121712 YP_002385443.1 CDS EFER_4445 NC_011740.1 4531183 4531389 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 4531183..4531389 Escherichia fergusonii ATCC 35469 7120487 YP_002385444.1 CDS EFER_4446 NC_011740.1 4531942 4532433 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 4531942..4532433 Escherichia fergusonii ATCC 35469 7123708 YP_002385445.1 CDS EFER_4447 NC_011740.1 4532433 4534535 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; DNA packaging protein of prophage ( terminase large subunit) 4532433..4534535 Escherichia fergusonii ATCC 35469 7120488 YP_002385446.1 CDS EFER_4448 NC_011740.1 4534526 4534744 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 4534526..4534744 Escherichia fergusonii ATCC 35469 7120489 YP_002385447.1 CDS EFER_4449 NC_011740.1 4534672 4536252 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; portal protein (head-tail preconnector protein) from prophage 4534672..4536252 Escherichia fergusonii ATCC 35469 7123169 YP_002385448.1 CDS EFER_4450 NC_011740.1 4536005 4538224 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; ATP-dependent Clp protease proteolytic subunit 4536005..4538224 Escherichia fergusonii ATCC 35469 7120490 YP_002385449.1 CDS EFER_4451 NC_011740.1 4538266 4538634 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 4538266..4538634 Escherichia fergusonii ATCC 35469 7120491 YP_002385450.1 CDS EFER_4452 NC_011740.1 4538627 4538902 D Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; hypothetical protein 4538627..4538902 Escherichia fergusonii ATCC 35469 7123170 YP_002385451.1 CDS EFER_4453 NC_011740.1 4538914 4539492 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein Z (GPZ) of prophage 4538914..4539492 Escherichia fergusonii ATCC 35469 7120492 YP_002385452.1 CDS EFER_4454 NC_011740.1 4539477 4539890 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein U 4539477..4539890 Escherichia fergusonii ATCC 35469 7120493 YP_002385453.1 CDS EFER_4455 NC_011740.1 4539896 4540645 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Major tail protein V 4539896..4540645 Escherichia fergusonii ATCC 35469 7120494 YP_002385454.1 CDS EFER_4456 NC_011740.1 4540664 4541092 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; minor tail protein 4540664..4541092 Escherichia fergusonii ATCC 35469 7120495 YP_002385455.1 CDS EFER_4457 NC_011740.1 4541101 4541430 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; minor tail protein T of prophage 4541101..4541430 Escherichia fergusonii ATCC 35469 7120496 YP_002385456.1 CDS EFER_4458 NC_011740.1 4541372 4544467 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; tail length tape measure protein from prophage 4541372..4544467 Escherichia fergusonii ATCC 35469 7120497 YP_002385457.1 CDS EFER_4459 NC_011740.1 4544467 4544796 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein M 4544467..4544796 Escherichia fergusonii ATCC 35469 7123709 YP_002385458.1 CDS EFER_4460 NC_011740.1 4544806 4545504 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Minor tail protein L 4544806..4545504 Escherichia fergusonii ATCC 35469 7120498 YP_002385459.1 CDS EFER_4461 NC_011740.1 4545510 4546253 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; tail fiber component K of prophage 4545510..4546253 Escherichia fergusonii ATCC 35469 7123171 YP_002385460.1 CDS EFER_4462 NC_011740.1 4546151 4546798 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; tail assembly protein I from prophage 4546151..4546798 Escherichia fergusonii ATCC 35469 7120499 YP_002385461.1 CDS EFER_4463 NC_011740.1 4546859 4550347 D Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin; Host specificity protein J of prophage 4546859..4550347 Escherichia fergusonii ATCC 35469 7120500 YP_002385462.1 CDS EFER_4464 NC_011740.1 4550415 4551014 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; Lom-like outer membrane protein of prophage 4550415..4551014 Escherichia fergusonii ATCC 35469 7123172 YP_002385463.1 CDS EFER_4465 NC_011740.1 4551073 4554453 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h : extrachromosomal origin; side tail fiber protein of prophage 4551073..4554453 Escherichia fergusonii ATCC 35469 7123710 YP_002385464.1 CDS tfaQ NC_011740.1 4554453 4555028 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor; tail fiber chaperone; Qin prophage 4554453..4555028 Escherichia fergusonii ATCC 35469 7120502 YP_002385465.1 CDS pinR NC_011740.1 4555126 4555716 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 14687564; Product type pe : enzyme; site-specific recombinase; DNA invertase; Rac prophage complement(4555126..4555716) Escherichia fergusonii ATCC 35469 7121988 YP_002385466.1 CDS ydfK NC_011740.1 4556096 4556362 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4556096..4556362) Escherichia fergusonii ATCC 35469 7120086 YP_002385467.1 CDS EFER_4470 NC_011740.1 4556938 4557186 R Evidence 2b : Function of strongly homologous gene; PubMedId : 11230150; Product type f : factor; DNA damage-inducible protein in prophage (dinI-like) complement(4556938..4557186) Escherichia fergusonii ATCC 35469 7122697 YP_002385468.1 CDS prfC NC_011740.1 4557379 4558992 D stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 4557379..4558992 Escherichia fergusonii ATCC 35469 7120503 YP_002385469.1 CDS osmY NC_011740.1 4559385 4559990 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 1317380, 8253679, 9298646, 9600841; Product type cp : cell process; hypothetical protein 4559385..4559990 Escherichia fergusonii ATCC 35469 7123108 YP_002385470.1 CDS ytjA NC_011740.1 4560099 4560278 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4560099..4560278 Escherichia fergusonii ATCC 35469 7119703 YP_002385471.1 CDS yjjU NC_011740.1 4560400 4561473 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; esterase 4560400..4561473 Escherichia fergusonii ATCC 35469 7119769 YP_002385472.1 CDS yjjV NC_011740.1 4561470 4562252 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; deoxyribonuclease YjjV 4561470..4562252 Escherichia fergusonii ATCC 35469 7123413 YP_002385473.1 CDS yjjW NC_011740.1 4562382 4563245 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : enzyme; pyruvate formate lyase activating enzyme complement(4562382..4563245) Escherichia fergusonii ATCC 35469 7122040 YP_002385474.1 CDS yjjI NC_011740.1 4563217 4564767 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4563217..4564767) Escherichia fergusonii ATCC 35469 7123970 YP_002385475.1 CDS deoC NC_011740.1 4565025 4565804 D catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 4565025..4565804 Escherichia fergusonii ATCC 35469 7122037 YP_002385476.1 CDS deoA NC_011740.1 4565882 4567204 D Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; thymidine phosphorylase 4565882..4567204 Escherichia fergusonii ATCC 35469 7122888 YP_002385477.1 CDS deoB NC_011740.1 4567256 4568479 D catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 4567256..4568479 Escherichia fergusonii ATCC 35469 7122886 YP_002385478.1 CDS deoD NC_011740.1 4568536 4569255 D catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 4568536..4569255 Escherichia fergusonii ATCC 35469 7122887 YP_002385479.1 CDS EFER_4482 NC_011740.1 4569416 4569679 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(4569416..4569679) Escherichia fergusonii ATCC 35469 7122889 YP_002385480.1 CDS lplA NC_011740.1 4569711 4570727 R Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins; lipoate-protein ligase A complement(4569711..4570727) Escherichia fergusonii ATCC 35469 7120504 YP_002385481.1 CDS ytjB NC_011740.1 4570755 4571399 R Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 2684780; hypothetical protein complement(4570755..4571399) Escherichia fergusonii ATCC 35469 7120850 YP_002385482.1 CDS serB NC_011740.1 4571505 4572473 D catalyzes the formation of serine from O-phosphoserine; phosphoserine phosphatase 4571505..4572473 Escherichia fergusonii ATCC 35469 7123591 YP_002385483.1 CDS radA NC_011740.1 4572522 4573904 D Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 4572522..4573904 Escherichia fergusonii ATCC 35469 7123920 YP_002385484.1 CDS nadR NC_011740.1 4573925 4575157 D catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; nicotinamide-nucleotide adenylyltransferase 4573925..4575157 Escherichia fergusonii ATCC 35469 7122344 YP_002385485.1 CDS EFER_4488 NC_011740.1 4575171 4575581 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4575171..4575581 Escherichia fergusonii ATCC 35469 7123199 YP_002385486.1 CDS EFER_4489 NC_011740.1 4575571 4575867 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 4575571..4575867 Escherichia fergusonii ATCC 35469 7123711 YP_002385487.1 CDS yjjK NC_011740.1 4575923 4577590 R ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein complement(4575923..4577590) Escherichia fergusonii ATCC 35469 7120505 YP_002385488.1 CDS slt NC_011740.1 4577801 4579738 D catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan; lytic murein transglycosylase 4577801..4579738 Escherichia fergusonii ATCC 35469 7122038 YP_002385489.1 CDS trpR NC_011740.1 4579828 4580154 D When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription; Trp operon repressor 4579828..4580154 Escherichia fergusonii ATCC 35469 7121789 YP_002385490.1 CDS yjjX NC_011740.1 4580148 4580672 R pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog; NTPase complement(4580148..4580672) Escherichia fergusonii ATCC 35469 7122167 YP_002385491.1 CDS ytjC NC_011740.1 4580715 4581362 D catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate; phosphoglycerate mutase 4580715..4581362 Escherichia fergusonii ATCC 35469 7123971 YP_002385492.1 CDS rob NC_011740.1 4581359 4582228 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 20264525, 20309711, 93194823, 96405618, 8449900; Product type r : regulator; DNA-binding transcriptional activator complement(4581359..4582228) Escherichia fergusonii ATCC 35469 7119770 YP_002385493.1 CDS creA NC_011740.1 4582439 4582912 D Evidence 4 : Homologs of previously reported genes of unknown function; PubMedId : 3531171, 8449900; hypothetical protein 4582439..4582912 Escherichia fergusonii ATCC 35469 7121432 YP_002385494.1 CDS creB NC_011740.1 4582925 4583614 D response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; DNA-binding response regulator CreB 4582925..4583614 Escherichia fergusonii ATCC 35469 7122802 YP_002385495.1 CDS creC NC_011740.1 4583614 4585038 D part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; sensory histidine kinase CreC 4583614..4585038 Escherichia fergusonii ATCC 35469 7122803 YP_002385496.1 CDS creD NC_011740.1 4585096 4586454 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type m : membrane component; hypothetical protein 4585096..4586454 Escherichia fergusonii ATCC 35469 7122804 YP_002385497.1 CDS arcA NC_011740.1 4586519 4587235 R Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15028693, 21167794, 21317451, 91008980, 91358353, 92380937, 9514749, 9632255, 2984198, 7565118, 9298646; Product type r : regulator; two-component response regulator complement(4586519..4587235) Escherichia fergusonii ATCC 35469 7122805 YP_002385498.1 CDS yjtD NC_011740.1 4587869 4588555 D member of the SPOUT superfamily of methyltransferases; RNA methyltransferase 4587869..4588555 Escherichia fergusonii ATCC 35469 7123176 YP_002394549.1 CDS repB NC_011743.1 450 1316 D Evidence 2b : Function of strongly homologous gene; PubMedId : 8469120; Product type r : regulator; Replication protein 450..1316 Escherichia fergusonii ATCC 35469 7133892 YP_002394550.1 CDS pEFER_0002 NC_011743.1 1637 1855 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(1637..1855) Escherichia fergusonii ATCC 35469 7133884 YP_002394551.1 CDS pEFER_0003 NC_011743.1 1840 2007 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 1840..2007 Escherichia fergusonii ATCC 35469 7133834 YP_002394552.1 CDS parA NC_011743.1 2249 3454 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 7961987; Product type e : enzyme; Plasmid partition protein A 2249..3454 Escherichia fergusonii ATCC 35469 7133835 YP_002394553.1 CDS parB NC_011743.1 3451 4428 D Evidence 2b : Function of strongly homologous gene; PubMedId : 16677298; Product type e : enzyme; Plasmid Partition par B protein 3451..4428 Escherichia fergusonii ATCC 35469 7133882 YP_002394554.1 CDS umuC NC_011743.1 4510 5781 R binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization; DNA polymerase V subunit UmuC complement(4510..5781) Escherichia fergusonii ATCC 35469 7133883 YP_002394555.1 CDS pEFER_0007 NC_011743.1 5781 6488 R Evidence 2b : Function of strongly homologous gene; PubMedId : 2129552, 10024589; Product type e : enzyme; Protein impA [Contains: Protein impA'] (modular protein) complement(5781..6488) Escherichia fergusonii ATCC 35469 7133887 YP_002394556.1 CDS pEFER_0008 NC_011743.1 6370 6537 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 6370..6537 Escherichia fergusonii ATCC 35469 7133836 YP_002394557.1 CDS pEFER_0009 NC_011743.1 6557 7309 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; reverse transcriptase/maturase, RetA (fragment) 6557..7309 Escherichia fergusonii ATCC 35469 7133837 YP_002394560.1 CDS pEFER_0012 NC_011743.1 7461 7736 D Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; transposase, ORF A, insertion element IS1 7461..7736 Escherichia fergusonii ATCC 35469 7133840 YP_002394561.1 CDS pEFER_0013 NC_011743.1 7655 8158 D Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; tranposase, ORF B, insertion element IS1 7655..8158 Escherichia fergusonii ATCC 35469 7133841 YP_002394562.1 CDS pEFER_0014 NC_011743.1 9008 9307 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 9008..9307 Escherichia fergusonii ATCC 35469 7133842 YP_002394563.1 CDS pEFER_0015 NC_011743.1 9620 10588 D Evidence 2b : Function of strongly homologous gene; PubMedId : 2993802; Product type pe : putative enzyme; transposase, IS903.B 9620..10588 Escherichia fergusonii ATCC 35469 7133843 YP_002394564.1 CDS pEFER_0016 NC_011743.1 10781 10999 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 10781..10999 Escherichia fergusonii ATCC 35469 7133844 YP_002394565.1 CDS pEFER_0017 NC_011743.1 11390 12061 D Evidence 7 : Gene remnant; Product type pe : putative enzyme; hypothetical protein 11390..12061 Escherichia fergusonii ATCC 35469 7133845 YP_002394566.1 CDS pEFER_0018 NC_011743.1 12093 12272 R Evidence 4 : Homologs of previously reported genes of unknown function; Product type h : extrachromosomal origin; phage protein complement(12093..12272) Escherichia fergusonii ATCC 35469 7133846 YP_002394567.1 CDS pEFER_0019 NC_011743.1 12109 12813 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 12109..12813 Escherichia fergusonii ATCC 35469 7133847 YP_002394568.1 CDS pEFER_0020 NC_011743.1 12882 13808 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 12882..13808 Escherichia fergusonii ATCC 35469 7133848 YP_002394569.1 CDS pEFER_0021 NC_011743.1 13818 14417 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 13818..14417 Escherichia fergusonii ATCC 35469 7133849 YP_002394570.1 CDS pEFER_0022 NC_011743.1 14405 14998 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 14405..14998 Escherichia fergusonii ATCC 35469 7133850 YP_002394571.1 CDS pEFER_0023 NC_011743.1 15017 18694 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; ATPase (modular protein) 15017..18694 Escherichia fergusonii ATCC 35469 7133851 YP_002394572.1 CDS pEFER_0024 NC_011743.1 18711 20474 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 18711..20474 Escherichia fergusonii ATCC 35469 7133852 YP_002394573.1 CDS pEFER_0025 NC_011743.1 20490 24143 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 20490..24143 Escherichia fergusonii ATCC 35469 7133853 YP_002394574.1 CDS pEFER_0026 NC_011743.1 24143 26800 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 24143..26800 Escherichia fergusonii ATCC 35469 7133854 YP_002394575.1 CDS pEFER_0027 NC_011743.1 26817 28892 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; ATP-dependent Lon protease 26817..28892 Escherichia fergusonii ATCC 35469 7133855 YP_002394576.1 CDS pEFER_0028 NC_011743.1 28885 29631 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(28885..29631) Escherichia fergusonii ATCC 35469 7133856 YP_002394577.1 CDS pEFER_0029 NC_011743.1 29000 29179 R Evidence 7 : Gene remnant; Product type pe : putative enzyme; hypothetical protein complement(29000..29179) Escherichia fergusonii ATCC 35469 7133857 YP_002394578.1 CDS tnpA NC_011743.1 29749 32634 R Evidence 2b : Function of strongly homologous gene; PubMedId : 3029727; Product type e : enzyme; Similar to TnpA transposase complement(29749..32634) Escherichia fergusonii ATCC 35469 7133858 YP_002394579.1 CDS pEFER_0031 NC_011743.1 32760 33383 D resolvase 32760..33383 Escherichia fergusonii ATCC 35469 7133891 YP_002394580.1 CDS pEFER_0032 NC_011743.1 33393 33689 D YahA protein 33393..33689 Escherichia fergusonii ATCC 35469 7133859 YP_002394581.1 CDS pEFER_0034 NC_011743.1 34376 37540 R Evidence 2b : Function of strongly homologous gene; PubMedId : 391406; Product type pe : putative enzyme; transposase complement(34376..37540) Escherichia fergusonii ATCC 35469 7133880 YP_002394582.1 CDS pEFER_0035 NC_011743.1 37509 38102 D Evidence 2b : Function of strongly homologous gene; Product type pe : putative enzyme; Resolvase transposon Tn3 37509..38102 Escherichia fergusonii ATCC 35469 7133861 YP_002394583.1 CDS bla NC_011743.1 38285 39145 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 358200, 3019092, 15769331; Product type e : enzyme; Beta-lactamase TEM precursor (Penicillinase) 38285..39145 Escherichia fergusonii ATCC 35469 7133862 YP_002394584.1 CDS pEFER_0037 NC_011743.1 39261 39854 D transposase (fragment) 39261..39854 Escherichia fergusonii ATCC 35469 7133879 YP_002394585.1 CDS tetD NC_011743.1 39864 40280 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10781570, 6094472, 6094471; Product type pr : putative regulator; TetD, putative operon control protein complement(39864..40280) Escherichia fergusonii ATCC 35469 7133863 YP_002394586.1 CDS tetC NC_011743.1 40293 40961 D Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10781570, 6094472, 6094471; Product type pr : putative regulator; transcriptional regulator TetC 40293..40961 Escherichia fergusonii ATCC 35469 7133890 YP_002394587.1 CDS tetA NC_011743.1 41074 42327 R Evidence 2b : Function of strongly homologous gene; PubMedId : 10783303; Product type t : transporter; Tetracycline resistance protein, class B (TETA(B) ) (Metal-tetracycline/H(+) antiporter) complement(41074..42327) Escherichia fergusonii ATCC 35469 7133889 YP_002394588.1 CDS pEFER_0041 NC_011743.1 42358 42984 D Evidence 2b : Function of strongly homologous gene; Product type r : regulator; tetracycline repressor protein TetR 42358..42984 Escherichia fergusonii ATCC 35469 7133888 YP_002394589.1 CDS pEFER_0042 NC_011743.1 42962 43648 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr : putative regulator; ArsR family regulatory protein complement(42962..43648) Escherichia fergusonii ATCC 35469 7133864 YP_002394590.1 CDS pEFER_0043 NC_011743.1 43656 44153 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(43656..44153) Escherichia fergusonii ATCC 35469 7133865 YP_002394591.1 CDS pEFER_0044 NC_011743.1 44035 44355 R Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe : putative enzyme; monooxygenase complement(44035..44355) Escherichia fergusonii ATCC 35469 7133866 YP_002394592.1 CDS jemA NC_011743.1 44799 46004 D Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 10781570; Product type c : carrier; glutamate permease 44799..46004 Escherichia fergusonii ATCC 35469 7133867 YP_002394593.1 CDS pEFER_0046 NC_011743.1 46370 47578 R Evidence 2b : Function of strongly homologous gene; PubMedId : 10781570; Product type pe : putative enzyme; transposase, IS10 complement(46370..47578) Escherichia fergusonii ATCC 35469 7133881 YP_002394594.1 CDS pEFER_0048 NC_011743.1 47864 48667 D Streptomycin 3''-kinase (Streptomycin 3''-phosphotransferase) (Streptomycin 6-phosphotransferase) (Streptomycin 6-kinase) 47864..48667 Escherichia fergusonii ATCC 35469 7133886 YP_002394595.1 CDS pEFER_0047 NC_011743.1 47886 48068 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein 47886..48068 Escherichia fergusonii ATCC 35469 7133870 YP_002394596.1 CDS pEFER_0049 NC_011743.1 48658 49503 D Streptomycin 3''-kinase 48658..49503 Escherichia fergusonii ATCC 35469 7133869 YP_002394597.1 CDS pEFER_0050 NC_011743.1 49475 50041 R Evidence 7 : Gene remnant; Product type pe : putative enzyme; hypothetical protein complement(49475..50041) Escherichia fergusonii ATCC 35469 7133871 YP_002394598.1 CDS pEFER_0051 NC_011743.1 49963 50205 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(49963..50205) Escherichia fergusonii ATCC 35469 7133872 YP_002394599.1 CDS pEFER_0052 NC_011743.1 50260 50847 R Evidence 7 : Gene remnant; Product type pe : putative enzyme; hypothetical protein complement(50260..50847) Escherichia fergusonii ATCC 35469 7133873 YP_002394600.1 CDS pEFER_0053 NC_011743.1 51383 51799 R Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein complement(51383..51799) Escherichia fergusonii ATCC 35469 7133874 YP_002394601.1 CDS pEFER_0054 NC_011743.1 51796 52026 R Virulence-associated protein vagC complement(51796..52026) Escherichia fergusonii ATCC 35469 7133875 YP_002394602.1 CDS pEFER_0055 NC_011743.1 52600 52950 D Evidence 4 : Homologs of previously reported genes of unknown function; hypothetical protein 52600..52950 Escherichia fergusonii ATCC 35469 7133876 YP_002394603.1 CDS pEFER_0056 NC_011743.1 53001 53744 D Evidence 5 : No homology to any previously reported sequences; hypothetical protein, putative membrane transporter 53001..53744 Escherichia fergusonii ATCC 35469 7133877 YP_002394604.1 CDS resD NC_011743.1 53741 54517 D Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 3027661; Product type e : enzyme; Resolvase (Protein D) 53741..54517 Escherichia fergusonii ATCC 35469 7133878 YP_002394605.1 CDS pEFER_0058 NC_011743.1 54575 54865 R Evidence 5 : No homology to any previously reported sequences; hypothetical protein complement(54575..54865) Escherichia fergusonii ATCC 35469 7133885 EFER_tRNA1 tRNA EFER_tRNA1 NC_011740.1 246800 246876 D tRNA-Ile 246800..246876 Escherichia fergusonii ATCC 35469 7123692 EFER_tRNA2 tRNA EFER_tRNA2 NC_011740.1 246919 246994 D tRNA-Ala 246919..246994 Escherichia fergusonii ATCC 35469 7119961 EFER_tRNA3 tRNA EFER_tRNA3 NC_011740.1 250352 250428 D tRNA-Asp 250352..250428 Escherichia fergusonii ATCC 35469 7120509 EFER_tRNA4 tRNA EFER_tRNA4 NC_011740.1 258576 258652 D tRNA-Asp 258576..258652 Escherichia fergusonii ATCC 35469 7122914 EFER_tRNA87 tRNA EFER_tRNA87 NC_011740.1 269140 269216 R tRNA-Met complement(269140..269216) Escherichia fergusonii ATCC 35469 7122301 EFER_tRNA86 tRNA EFER_tRNA86 NC_011740.1 269250 269326 R tRNA-Met complement(269250..269326) Escherichia fergusonii ATCC 35469 7122242 EFER_tRNA85 tRNA EFER_tRNA85 NC_011740.1 269360 269436 R tRNA-Met complement(269360..269436) Escherichia fergusonii ATCC 35469 7123449 EFER_tRNA5 tRNA EFER_tRNA5 NC_011740.1 391755 391847 D tRNA-Ser 391755..391847 Escherichia fergusonii ATCC 35469 7122823 EFER_tRNA6 tRNA EFER_tRNA6 NC_011740.1 391851 391927 D tRNA-Arg 391851..391927 Escherichia fergusonii ATCC 35469 7120058 EFER_tRNA7 tRNA EFER_tRNA7 NC_011740.1 392127 392203 D tRNA-Arg 392127..392203 Escherichia fergusonii ATCC 35469 7120065 EFER_tRNA8 tRNA EFER_tRNA8 NC_011740.1 392266 392342 D tRNA-Arg 392266..392342 Escherichia fergusonii ATCC 35469 7120074 EFER_tRNA9 tRNA EFER_tRNA9 NC_011740.1 392541 392617 D tRNA-Arg 392541..392617 Escherichia fergusonii ATCC 35469 7120082 EFER_tRNA10 tRNA EFER_tRNA10 NC_011740.1 425974 426054 D tRNA-OTHER 425974..426054 Escherichia fergusonii ATCC 35469 7121485 EFER_tRNA11 tRNA EFER_tRNA11 NC_011740.1 483460 483535 D tRNA-Glu 483460..483535 Escherichia fergusonii ATCC 35469 7123149 EFER_tRNA12 tRNA EFER_tRNA12 NC_011740.1 590549 590625 D tRNA-Arg 590549..590625 Escherichia fergusonii ATCC 35469 7123002 EFER_tRNA84 tRNA EFER_tRNA84 NC_011740.1 785746 785821 R tRNA-Lys complement(785746..785821) Escherichia fergusonii ATCC 35469 7122383 EFER_tRNA83 tRNA EFER_tRNA83 NC_011740.1 785826 785901 R tRNA-Val complement(785826..785901) Escherichia fergusonii ATCC 35469 7122179 EFER_tRNA82 tRNA EFER_tRNA82 NC_011740.1 785948 786023 R tRNA-Val complement(785948..786023) Escherichia fergusonii ATCC 35469 7123099 EFER_tRNA81 tRNA EFER_tRNA81 NC_011740.1 786068 786143 R tRNA-Val complement(786068..786143) Escherichia fergusonii ATCC 35469 7120085 EFER_tRNA13 tRNA EFER_tRNA13 NC_011740.1 788840 788915 D tRNA-Ala 788840..788915 Escherichia fergusonii ATCC 35469 7121445 EFER_tRNA14 tRNA EFER_tRNA14 NC_011740.1 788955 789030 D tRNA-Ala 788955..789030 Escherichia fergusonii ATCC 35469 7123090 EFER_tRNA80 tRNA EFER_tRNA80 NC_011740.1 833186 833257 R tRNA-Arg complement(833186..833257) Escherichia fergusonii ATCC 35469 7120748 EFER_tRNA79 tRNA EFER_tRNA79 NC_011740.1 1060109 1060196 R tRNA-Ser complement(1060109..1060196) Escherichia fergusonii ATCC 35469 7120258 EFER_tRNA15 tRNA EFER_tRNA15 NC_011740.1 1151859 1151946 D tRNA-Ser 1151859..1151946 Escherichia fergusonii ATCC 35469 7119906 EFER_tRNA16 tRNA EFER_tRNA16 NC_011740.1 1222388 1222463 D tRNA-Gly 1222388..1222463 Escherichia fergusonii ATCC 35469 7124069 EFER_tRNA17 tRNA EFER_tRNA17 NC_011740.1 1222518 1222591 D tRNA-Cys 1222518..1222591 Escherichia fergusonii ATCC 35469 7120029 EFER_tRNA18 tRNA EFER_tRNA18 NC_011740.1 1222604 1222690 D tRNA-Leu 1222604..1222690 Escherichia fergusonii ATCC 35469 7120030 EFER_tRNA78 tRNA EFER_tRNA78 NC_011740.1 1416752 1416828 R tRNA-Val complement(1416752..1416828) Escherichia fergusonii ATCC 35469 7122713 EFER_tRNA77 tRNA EFER_tRNA77 NC_011740.1 1416833 1416909 R tRNA-Val complement(1416833..1416909) Escherichia fergusonii ATCC 35469 7120080 EFER_tRNA19 tRNA EFER_tRNA19 NC_011740.1 1772446 1772530 D tRNA-Tyr 1772446..1772530 Escherichia fergusonii ATCC 35469 7122329 EFER_tRNA20 tRNA EFER_tRNA20 NC_011740.1 1772565 1772649 D tRNA-Tyr 1772565..1772649 Escherichia fergusonii ATCC 35469 7120031 EFER_tRNA76 tRNA EFER_tRNA76 NC_011740.1 1830231 1830317 R tRNA-OTHER complement(1830231..1830317) Escherichia fergusonii ATCC 35469 7120934 EFER_tRNA21 tRNA EFER_tRNA21 NC_011740.1 1940250 1940337 D tRNA-Ser 1940250..1940337 Escherichia fergusonii ATCC 35469 7119913 EFER_tRNA75 tRNA EFER_tRNA75 NC_011740.1 2000969 2001058 R tRNA-Ser complement(2000969..2001058) Escherichia fergusonii ATCC 35469 7120629 EFER_tRNA22 tRNA EFER_tRNA22 NC_011740.1 2002050 2002125 D tRNA-Asn 2002050..2002125 Escherichia fergusonii ATCC 35469 7123339 EFER_tRNA23 tRNA EFER_tRNA23 NC_011740.1 2004459 2004534 D tRNA-Asn 2004459..2004534 Escherichia fergusonii ATCC 35469 7120656 EFER_tRNA74 tRNA EFER_tRNA74 NC_011740.1 2041228 2041303 R tRNA-Asn complement(2041228..2041303) Escherichia fergusonii ATCC 35469 7121782 EFER_tRNA24 tRNA EFER_tRNA24 NC_011740.1 2043051 2043126 D tRNA-Asn 2043051..2043126 Escherichia fergusonii ATCC 35469 7121548 EFER_tRNA25 tRNA EFER_tRNA25 NC_011740.1 2341396 2341472 D tRNA-Pro 2341396..2341472 Escherichia fergusonii ATCC 35469 7119801 EFER_tRNA73 tRNA EFER_tRNA73 NC_011740.1 2416492 2416567 R tRNA-Lys complement(2416492..2416567) Escherichia fergusonii ATCC 35469 7120657 EFER_tRNA72 tRNA EFER_tRNA72 NC_011740.1 2416601 2416676 R tRNA-Lys complement(2416601..2416676) Escherichia fergusonii ATCC 35469 7120077 EFER_tRNA71 tRNA EFER_tRNA71 NC_011740.1 2416823 2416898 R tRNA-Lys complement(2416823..2416898) Escherichia fergusonii ATCC 35469 7120076 EFER_tRNA70 tRNA EFER_tRNA70 NC_011740.1 2416902 2416977 R tRNA-Val complement(2416902..2416977) Escherichia fergusonii ATCC 35469 7120075 EFER_tRNA69 tRNA EFER_tRNA69 NC_011740.1 2417030 2417105 R tRNA-Lys complement(2417030..2417105) Escherichia fergusonii ATCC 35469 7123097 EFER_tRNA68 tRNA EFER_tRNA68 NC_011740.1 2417108 2417183 R tRNA-Val complement(2417108..2417183) Escherichia fergusonii ATCC 35469 7120073 EFER_tRNA67 tRNA EFER_tRNA67 NC_011740.1 2417219 2417294 R tRNA-Lys complement(2417219..2417294) Escherichia fergusonii ATCC 35469 7120072 EFER_tRNA26 tRNA EFER_tRNA26 NC_011740.1 2502288 2502364 D tRNA-Met 2502288..2502364 Escherichia fergusonii ATCC 35469 7121908 EFER_tRNA27 tRNA EFER_tRNA27 NC_011740.1 2502373 2502457 D tRNA-Leu 2502373..2502457 Escherichia fergusonii ATCC 35469 7120037 EFER_tRNA28 tRNA EFER_tRNA28 NC_011740.1 2502562 2502636 D tRNA-Gln 2502562..2502636 Escherichia fergusonii ATCC 35469 7120038 EFER_tRNA29 tRNA EFER_tRNA29 NC_011740.1 2502671 2502745 D tRNA-Gln 2502671..2502745 Escherichia fergusonii ATCC 35469 7120039 EFER_tRNA30 tRNA EFER_tRNA30 NC_011740.1 2502761 2502837 D tRNA-Met 2502761..2502837 Escherichia fergusonii ATCC 35469 7120040 EFER_tRNA31 tRNA EFER_tRNA31 NC_011740.1 2502886 2502960 D tRNA-Gln 2502886..2502960 Escherichia fergusonii ATCC 35469 7123092 EFER_tRNA32 tRNA EFER_tRNA32 NC_011740.1 2502998 2503072 D tRNA-Gln 2502998..2503072 Escherichia fergusonii ATCC 35469 7120042 EFER_tRNA66 tRNA EFER_tRNA66 NC_011740.1 2795024 2795099 R tRNA-Thr complement(2795024..2795099) Escherichia fergusonii ATCC 35469 7120751 EFER_tRNA65 tRNA EFER_tRNA65 NC_011740.1 2873434 2873507 R tRNA-Gly complement(2873434..2873507) Escherichia fergusonii ATCC 35469 7120752 EFER_tRNA33 tRNA EFER_tRNA33 NC_011740.1 2974812 2974887 D tRNA-Phe 2974812..2974887 Escherichia fergusonii ATCC 35469 7120404 EFER_tRNA34 tRNA EFER_tRNA34 NC_011740.1 3081119 3081194 D tRNA-Met 3081119..3081194 Escherichia fergusonii ATCC 35469 7119871 EFER_tRNA64 tRNA EFER_tRNA64 NC_011740.1 3201829 3201913 R tRNA-Leu complement(3201829..3201913) Escherichia fergusonii ATCC 35469 7124038 EFER_tRNA63 tRNA EFER_tRNA63 NC_011740.1 3237966 3238042 R tRNA-Met complement(3237966..3238042) Escherichia fergusonii ATCC 35469 7123066 EFER_tRNA62 tRNA EFER_tRNA62 NC_011740.1 3241646 3241732 R tRNA-Leu complement(3241646..3241732) Escherichia fergusonii ATCC 35469 7119888 EFER_tRNA61 tRNA EFER_tRNA61 NC_011740.1 3339662 3339737 R tRNA-Thr complement(3339662..3339737) Escherichia fergusonii ATCC 35469 7123174 EFER_tRNA60 tRNA EFER_tRNA60 NC_011740.1 3343051 3343126 R tRNA-Ala complement(3343051..3343126) Escherichia fergusonii ATCC 35469 7121902 EFER_tRNA59 tRNA EFER_tRNA59 NC_011740.1 3343169 3343245 R tRNA-Ile complement(3343169..3343245) Escherichia fergusonii ATCC 35469 7120066 EFER_tRNA58 tRNA EFER_tRNA58 NC_011740.1 3623659 3623735 R tRNA-Pro complement(3623659..3623735) Escherichia fergusonii ATCC 35469 7121163 EFER_tRNA57 tRNA EFER_tRNA57 NC_011740.1 3715554 3715629 R tRNA-Ala complement(3715554..3715629) Escherichia fergusonii ATCC 35469 7121901 EFER_tRNA56 tRNA EFER_tRNA56 NC_011740.1 3715672 3715748 R tRNA-Ile complement(3715672..3715748) Escherichia fergusonii ATCC 35469 7123096 EFER_tRNA55 tRNA EFER_tRNA55 NC_011740.1 3800943 3801019 R tRNA-Pro complement(3800943..3801019) Escherichia fergusonii ATCC 35469 7120565 EFER_tRNA54 tRNA EFER_tRNA54 NC_011740.1 3801062 3801149 R tRNA-Leu complement(3801062..3801149) Escherichia fergusonii ATCC 35469 7120062 EFER_tRNA53 tRNA EFER_tRNA53 NC_011740.1 3801170 3801245 R tRNA-His complement(3801170..3801245) Escherichia fergusonii ATCC 35469 7120061 EFER_tRNA52 tRNA EFER_tRNA52 NC_011740.1 3801304 3801380 R tRNA-Arg complement(3801304..3801380) Escherichia fergusonii ATCC 35469 7120060 EFER_tRNA51 tRNA EFER_tRNA51 NC_011740.1 3835837 3835912 R tRNA-Trp complement(3835837..3835912) Escherichia fergusonii ATCC 35469 7120635 EFER_tRNA50 tRNA EFER_tRNA50 NC_011740.1 3835921 3835997 R tRNA-Asp complement(3835921..3835997) Escherichia fergusonii ATCC 35469 7123094 EFER_tRNA49 tRNA EFER_tRNA49 NC_011740.1 3839366 3839441 R tRNA-Glu complement(3839366..3839441) Escherichia fergusonii ATCC 35469 7123946 EFER_tRNA48 tRNA EFER_tRNA48 NC_011740.1 3872447 3872522 R tRNA-Thr complement(3872447..3872522) Escherichia fergusonii ATCC 35469 7122485 EFER_tRNA47 tRNA EFER_tRNA47 NC_011740.1 3872529 3872603 R tRNA-Gly complement(3872529..3872603) Escherichia fergusonii ATCC 35469 7120056 EFER_tRNA46 tRNA EFER_tRNA46 NC_011740.1 3872720 3872804 R tRNA-Tyr complement(3872720..3872804) Escherichia fergusonii ATCC 35469 7120055 EFER_tRNA45 tRNA EFER_tRNA45 NC_011740.1 3872813 3872888 R tRNA-Thr complement(3872813..3872888) Escherichia fergusonii ATCC 35469 7120054 EFER_tRNA44 tRNA EFER_tRNA44 NC_011740.1 3879671 3879746 R tRNA-Glu complement(3879671..3879746) Escherichia fergusonii ATCC 35469 7121900 EFER_tRNA35 tRNA EFER_tRNA35 NC_011740.1 4053751 4053841 D tRNA-Sec 4053751..4053841 Escherichia fergusonii ATCC 35469 7121818 EFER_tRNA36 tRNA EFER_tRNA36 NC_011740.1 4162968 4163043 D tRNA-Glu 4162968..4163043 Escherichia fergusonii ATCC 35469 7120387 EFER_tRNA43 tRNA EFER_tRNA43 NC_011740.1 4295119 4295194 R tRNA-Phe complement(4295119..4295194) Escherichia fergusonii ATCC 35469 7121031 EFER_tRNA37 tRNA EFER_tRNA37 NC_011740.1 4325691 4325766 D tRNA-Gly 4325691..4325766 Escherichia fergusonii ATCC 35469 7120558 EFER_tRNA38 tRNA EFER_tRNA38 NC_011740.1 4325803 4325878 D tRNA-Gly 4325803..4325878 Escherichia fergusonii ATCC 35469 7120046 EFER_tRNA39 tRNA EFER_tRNA39 NC_011740.1 4325915 4325990 D tRNA-Gly 4325915..4325990 Escherichia fergusonii ATCC 35469 7120047 EFER_tRNA42 tRNA EFER_tRNA42 NC_011740.1 4508574 4508660 R tRNA-Leu complement(4508574..4508660) Escherichia fergusonii ATCC 35469 7122041 EFER_tRNA41 tRNA EFER_tRNA41 NC_011740.1 4508694 4508780 R tRNA-Leu complement(4508694..4508780) Escherichia fergusonii ATCC 35469 7120050 EFER_tRNA40 tRNA EFER_tRNA40 NC_011740.1 4508809 4508895 R tRNA-Leu complement(4508809..4508895) Escherichia fergusonii ATCC 35469 7123636 EFER_16S_5 rRNA EFER_16S_5 NC_011740.1 245190 246731 D ribosomal RNA 16S 245190..246731 Escherichia fergusonii ATCC 35469 7123723 EFER_23S_5 rRNA EFER_23S_5 NC_011740.1 247178 250081 D ribosomal RNA 23S 247178..250081 Escherichia fergusonii ATCC 35469 7120032 EFER_5S_6 rRNA EFER_5S_6 NC_011740.1 250180 250299 D ribosomal RNA 5S 250180..250299 Escherichia fergusonii ATCC 35469 7123947 EFER_16S_6 rRNA EFER_16S_6 NC_011740.1 481833 483374 D ribosomal RNA 16S 481833..483374 Escherichia fergusonii ATCC 35469 7123772 EFER_23S_6 rRNA EFER_23S_6 NC_011740.1 483729 486632 D ribosomal RNA 23S 483729..486632 Escherichia fergusonii ATCC 35469 7120026 EFER_5S_7 rRNA EFER_5S_7 NC_011740.1 486726 486845 D ribosomal RNA 5S 486726..486845 Escherichia fergusonii ATCC 35469 7121903 EFER_5S_5 rRNA EFER_5S_5 NC_011740.1 3339509 3339621 R ribosomal RNA 5S complement(3339509..3339621) Escherichia fergusonii ATCC 35469 7122249 EFER_5S_4 rRNA EFER_5S_4 NC_011740.1 3339750 3339869 R ribosomal RNA 5S complement(3339750..3339869) Escherichia fergusonii ATCC 35469 7120067 EFER_23S_4 rRNA EFER_23S_4 NC_011740.1 3339963 3342867 R ribosomal RNA 23S complement(3339963..3342867) Escherichia fergusonii ATCC 35469 7120508 EFER_16S_4 rRNA EFER_16S_4 NC_011740.1 3343314 3344855 R ribosomal RNA 16S complement(3343314..3344855) Escherichia fergusonii ATCC 35469 7120064 EFER_5S_3 rRNA EFER_5S_3 NC_011740.1 3712249 3712368 R ribosomal RNA 5S complement(3712249..3712368) Escherichia fergusonii ATCC 35469 7120948 EFER_23S_3 rRNA EFER_23S_3 NC_011740.1 3712467 3715370 R ribosomal RNA 23S complement(3712467..3715370) Escherichia fergusonii ATCC 35469 7120507 EFER_16S_3 rRNA EFER_16S_3 NC_011740.1 3715817 3717358 R ribosomal RNA 16S complement(3715817..3717358) Escherichia fergusonii ATCC 35469 7120063 EFER_5S_2 rRNA EFER_5S_2 NC_011740.1 3836050 3836169 R ribosomal RNA 5S complement(3836050..3836169) Escherichia fergusonii ATCC 35469 7120059 EFER_23S_2 rRNA EFER_23S_2 NC_011740.1 3836268 3839171 R ribosomal RNA 23S complement(3836268..3839171) Escherichia fergusonii ATCC 35469 7123173 EFER_16S_2 rRNA EFER_16S_2 NC_011740.1 3839527 3841068 R ribosomal RNA 16S complement(3839527..3841068) Escherichia fergusonii ATCC 35469 7120057 EFER_5S_1 rRNA EFER_5S_1 NC_011740.1 3876354 3876473 R ribosomal RNA 5S complement(3876354..3876473) Escherichia fergusonii ATCC 35469 7120645 EFER_23S_1 rRNA EFER_23S_1 NC_011740.1 3876572 3879476 R ribosomal RNA 23S complement(3876572..3879476) Escherichia fergusonii ATCC 35469 7120506 EFER_16S_1 rRNA EFER_16S_1 NC_011740.1 3879832 3881373 R ribosomal RNA 16S complement(3879832..3881373) Escherichia fergusonii ATCC 35469 7120052 EFER_16S_7 rRNA EFER_16S_7 NC_011740.1 4161341 4162882 D ribosomal RNA 16S 4161341..4162882 Escherichia fergusonii ATCC 35469 7121837 EFER_23S_7 rRNA EFER_23S_7 NC_011740.1 4163238 4166141 D ribosomal RNA 23S 4163238..4166141 Escherichia fergusonii ATCC 35469 7123634 EFER_5S_8 rRNA EFER_5S_8 NC_011740.1 4166240 4166359 D ribosomal RNA 5S 4166240..4166359 Escherichia fergusonii ATCC 35469 7121904