-- dump date   	20140619_092158
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1087448000001	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
1087448000002	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1087448000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1087448000004	Walker A motif; other site
1087448000005	ATP binding site [chemical binding]; other site
1087448000006	Walker B motif; other site
1087448000007	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1087448000008	arginine finger; other site
1087448000009	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1087448000010	DnaA box-binding interface [nucleotide binding]; other site
1087448000011	DNA polymerase III subunit beta; Validated; Region: PRK05643
1087448000012	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1087448000013	putative DNA binding surface [nucleotide binding]; other site
1087448000014	dimer interface [polypeptide binding]; other site
1087448000015	beta-clamp/clamp loader binding surface; other site
1087448000016	beta-clamp/translesion DNA polymerase binding surface; other site
1087448000017	S4 domain protein YaaA; Region: YaaA_near_RecF; TIGR02988
1087448000018	recombination protein F; Reviewed; Region: recF; PRK00064
1087448000019	ATP-binding cassette domain of RecF; Region: ABC_RecF; cd03242
1087448000020	Walker A/P-loop; other site
1087448000021	ATP binding site [chemical binding]; other site
1087448000022	Q-loop/lid; other site
1087448000023	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1087448000024	ABC transporter signature motif; other site
1087448000025	Walker B; other site
1087448000026	D-loop; other site
1087448000027	H-loop/switch region; other site
1087448000028	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
1087448000029	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1087448000030	Mg2+ binding site [ion binding]; other site
1087448000031	G-X-G motif; other site
1087448000032	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1087448000033	anchoring element; other site
1087448000034	dimer interface [polypeptide binding]; other site
1087448000035	ATP binding site [chemical binding]; other site
1087448000036	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1087448000037	active site
1087448000038	putative metal-binding site [ion binding]; other site
1087448000039	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1087448000040	DNA gyrase subunit A; Validated; Region: PRK05560
1087448000041	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1087448000042	CAP-like domain; other site
1087448000043	active site
1087448000044	primary dimer interface [polypeptide binding]; other site
1087448000045	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1087448000046	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1087448000047	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1087448000048	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1087448000049	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1087448000050	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1087448000051	Zn2+ binding site [ion binding]; other site
1087448000052	Mg2+ binding site [ion binding]; other site
1087448000053	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
1087448000054	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1087448000055	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
1087448000056	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1087448000057	active site
1087448000058	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1087448000059	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1087448000060	DNA-binding site [nucleotide binding]; DNA binding site
1087448000061	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1087448000062	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1087448000063	homodimer interface [polypeptide binding]; other site
1087448000064	catalytic residue [active]
1087448000065	pyridoxal biosynthesis lyase PdxS; Provisional; Region: PRK04180
1087448000066	pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Region: TIGR00343
1087448000067	phosphate binding site [ion binding]; other site
1087448000068	Glutamine Amidotransferase (GATase_I) involved in pyridoxine biosynthesis; Region: GATase1_PB; cd01749
1087448000069	predicted active site [active]
1087448000070	catalytic triad [active]
1087448000071	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1087448000072	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
1087448000073	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1087448000074	seryl-tRNA synthetase; Provisional; Region: PRK05431
1087448000075	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1087448000076	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1087448000077	dimer interface [polypeptide binding]; other site
1087448000078	active site
1087448000079	motif 1; other site
1087448000080	motif 2; other site
1087448000081	motif 3; other site
1087448000082	Mycothiol maleylpyruvate isomerase N-terminal domain; Region: MDMPI_N; pfam11716
1087448000083	DinB superfamily; Region: DinB_2; pfam12867
1087448000084	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
1087448000085	Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673
1087448000086	Substrate-binding site [chemical binding]; other site
1087448000087	Substrate specificity [chemical binding]; other site
1087448000088	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
1087448000089	Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673
1087448000090	Substrate-binding site [chemical binding]; other site
1087448000091	Substrate specificity [chemical binding]; other site
1087448000092	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1087448000093	nucleoside/Zn binding site; other site
1087448000094	dimer interface [polypeptide binding]; other site
1087448000095	catalytic motif [active]
1087448000096	DNA polymerase III subunits gamma and tau; Validated; Region: PRK05563
1087448000097	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1087448000098	Walker A motif; other site
1087448000099	ATP binding site [chemical binding]; other site
1087448000100	Walker B motif; other site
1087448000101	arginine finger; other site
1087448000102	hypothetical protein; Validated; Region: PRK00153
1087448000103	recombination protein RecR; Reviewed; Region: recR; PRK00076
1087448000104	RecR protein; Region: RecR; pfam02132
1087448000105	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1087448000106	putative active site [active]
1087448000107	putative metal-binding site [ion binding]; other site
1087448000108	tetramer interface [polypeptide binding]; other site
1087448000109	Protein of unknown function (DUF2508); Region: DUF2508; pfam10704
1087448000110	Arginine/lysine/ornithine decarboxylases [Amino acid transport and metabolism]; Region: LdcC; COG1982
1087448000111	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1087448000112	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1087448000113	catalytic residue [active]
1087448000114	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1087448000115	thymidylate kinase; Validated; Region: tmk; PRK00698
1087448000116	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1087448000117	TMP-binding site; other site
1087448000118	ATP-binding site [chemical binding]; other site
1087448000119	Protein of unknown function (DUF970); Region: DUF970; pfam06153
1087448000120	DNA polymerase III subunit delta'; Validated; Region: PRK08058
1087448000121	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1087448000122	Uncharacterized homolog of PSP1 [Function unknown]; Region: COG1774
1087448000123	DNA replication intiation control protein YabA; Reviewed; Region: PRK13169
1087448000124	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1087448000125	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1087448000126	S-adenosylmethionine binding site [chemical binding]; other site
1087448000127	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
1087448000128	GIY-YIG motif/motif A; other site
1087448000129	putative active site [active]
1087448000130	putative metal binding site [ion binding]; other site
1087448000131	Predicted methyltransferases [General function prediction only]; Region: COG0313
1087448000132	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1087448000133	putative SAM binding site [chemical binding]; other site
1087448000134	putative homodimer interface [polypeptide binding]; other site
1087448000135	SpoVT / AbrB like domain; Region: SpoVT_AbrB; smart00966
1087448000136	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1087448000137	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
1087448000138	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1087448000139	active site
1087448000140	HIGH motif; other site
1087448000141	KMSKS motif; other site
1087448000142	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1087448000143	tRNA binding surface [nucleotide binding]; other site
1087448000144	anticodon binding site; other site
1087448000145	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
1087448000146	dimer interface [polypeptide binding]; other site
1087448000147	putative tRNA-binding site [nucleotide binding]; other site
1087448000148	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
1087448000149	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1087448000150	active site
1087448000151	Domain of unknown function (DUF348); Region: DUF348; pfam03990
1087448000152	Domain of unknown function (DUF348); Region: DUF348; pfam03990
1087448000153	Domain of unknown function (DUF348); Region: DUF348; pfam03990
1087448000154	G5 domain; Region: G5; pfam07501
1087448000155	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3584
1087448000156	ribonuclease M5; Region: 5S_RNA_mat_M5; TIGR00334
1087448000157	TOPRIM_ RNase M5_like: The topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain found in Ribonuclease M5: (RNase M5) and other small primase-like proteins from bacteria and archaea.  RNase M5 catalyzes the maturation of 5S rRNA in low...; Region: TOPRIM_RNase_M5_like; cd01027
1087448000158	putative active site [active]
1087448000159	putative metal binding site [ion binding]; other site
1087448000160	Domain of unknown function (DUF4093); Region: DUF4093; pfam13331
1087448000161	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1087448000162	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1087448000163	S-adenosylmethionine binding site [chemical binding]; other site
1087448000164	Protein of unknown function (DUF1021); Region: DUF1021; pfam06257
1087448000165	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00128
1087448000166	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1087448000167	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1087448000168	pur operon repressor; Provisional; Region: PRK09213
1087448000169	Bacterial purine repressor, N-terminal; Region: PuR_N; pfam09182
1087448000170	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1087448000171	active site
1087448000172	regulatory protein SpoVG; Reviewed; Region: PRK13259
1087448000173	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14354
1087448000174	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1087448000175	Substrate binding site; other site
1087448000176	Mg++ binding site; other site
1087448000177	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
1087448000178	active site
1087448000179	substrate binding site [chemical binding]; other site
1087448000180	CoA binding site [chemical binding]; other site
1087448000181	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1087448000182	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1087448000183	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1087448000184	active site
1087448000185	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1087448000186	putative active site [active]
1087448000187	catalytic residue [active]
1087448000188	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
1087448000189	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1087448000190	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1087448000191	ATP binding site [chemical binding]; other site
1087448000192	putative Mg++ binding site [ion binding]; other site
1087448000193	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1087448000194	nucleotide binding region [chemical binding]; other site
1087448000195	ATP-binding site [chemical binding]; other site
1087448000196	TRCF domain; Region: TRCF; pfam03461
1087448000197	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1087448000198	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
1087448000199	Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain [General function prediction only]; Region: COG3956
1087448000200	N-terminal S-AdoMet dependent methylase domain of Bacillus subtilis YabN and related proteins; Region: YabN_N; cd11723
1087448000201	putative SAM binding site [chemical binding]; other site
1087448000202	putative homodimer interface [polypeptide binding]; other site
1087448000203	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
1087448000204	homodimer interface [polypeptide binding]; other site
1087448000205	metal binding site [ion binding]; metal-binding site
1087448000206	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
1087448000207	homodimer interface [polypeptide binding]; other site
1087448000208	active site
1087448000209	putative chemical substrate binding site [chemical binding]; other site
1087448000210	metal binding site [ion binding]; metal-binding site
1087448000211	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1087448000212	RNA binding surface [nucleotide binding]; other site
1087448000213	Septum formation initiator [Cell division and chromosome partitioning]; Region: COG2919
1087448000214	Septum formation initiator; Region: DivIC; pfam04977
1087448000215	hypothetical protein; Provisional; Region: PRK08582
1087448000216	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
1087448000217	RNA binding site [nucleotide binding]; other site
1087448000218	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
1087448000219	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1087448000220	Ligand Binding Site [chemical binding]; other site
1087448000221	TilS substrate C-terminal domain; Region: TilS_C; smart00977
1087448000222	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1087448000223	active site
1087448000224	FtsH Extracellular; Region: FtsH_ext; pfam06480
1087448000225	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
1087448000226	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1087448000227	Walker A motif; other site
1087448000228	ATP binding site [chemical binding]; other site
1087448000229	Walker B motif; other site
1087448000230	arginine finger; other site
1087448000231	Peptidase family M41; Region: Peptidase_M41; pfam01434
1087448000232	pantothenate kinase; Reviewed; Region: PRK13318
1087448000233	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
1087448000234	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
1087448000235	dimerization interface [polypeptide binding]; other site
1087448000236	domain crossover interface; other site
1087448000237	redox-dependent activation switch; other site
1087448000238	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1087448000239	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1087448000240	dimer interface [polypeptide binding]; other site
1087448000241	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1087448000242	catalytic residue [active]
1087448000243	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1087448000244	Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism]; Region: TrpE; COG0147
1087448000245	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1087448000246	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
1087448000247	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1087448000248	glutamine binding [chemical binding]; other site
1087448000249	catalytic triad [active]
1087448000250	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1087448000251	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cd00449
1087448000252	homodimer interface [polypeptide binding]; other site
1087448000253	substrate-cofactor binding pocket; other site
1087448000254	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1087448000255	catalytic residue [active]
1087448000256	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1087448000257	dihydropteroate synthase; Region: DHPS; TIGR01496
1087448000258	substrate binding pocket [chemical binding]; other site
1087448000259	dimer interface [polypeptide binding]; other site
1087448000260	inhibitor binding site; inhibition site
1087448000261	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
1087448000262	homooctamer interface [polypeptide binding]; other site
1087448000263	active site
1087448000264	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
1087448000265	catalytic center binding site [active]
1087448000266	ATP binding site [chemical binding]; other site
1087448000267	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
1087448000268	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1087448000269	FMN binding site [chemical binding]; other site
1087448000270	active site
1087448000271	catalytic residues [active]
1087448000272	substrate binding site [chemical binding]; other site
1087448000273	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
1087448000274	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1087448000275	dimer interface [polypeptide binding]; other site
1087448000276	putative anticodon binding site; other site
1087448000277	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1087448000278	motif 1; other site
1087448000279	active site
1087448000280	motif 2; other site
1087448000281	motif 3; other site
1087448000282	Firmicute transcriptional repressor of class III stress genes (CtsR); Region: CtsR; pfam05848
1087448000283	Modulator of heat shock repressor CtsR, McsA [Signal transduction    mechanisms]; Region: COG3880
1087448000284	ATP:guanido phosphotransferase; Provisional; Region: PRK01059
1087448000285	Phosphagen (guanidino) kinases found in bacteria; Region: bacterial_phosphagen_kinase; cd07930
1087448000286	ADP binding site [chemical binding]; other site
1087448000287	phosphagen binding site; other site
1087448000288	substrate specificity loop; other site
1087448000289	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
1087448000290	Clp amino terminal domain; Region: Clp_N; pfam02861
1087448000291	Clp amino terminal domain; Region: Clp_N; pfam02861
1087448000292	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1087448000293	Walker A motif; other site
1087448000294	ATP binding site [chemical binding]; other site
1087448000295	Walker B motif; other site
1087448000296	arginine finger; other site
1087448000297	UvrB/uvrC motif; Region: UVR; pfam02151
1087448000298	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1087448000299	Walker A motif; other site
1087448000300	ATP binding site [chemical binding]; other site
1087448000301	Walker B motif; other site
1087448000302	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1087448000303	DNA repair protein RadA; Provisional; Region: PRK11823
1087448000304	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
1087448000305	Walker A motif/ATP binding site; other site
1087448000306	ATP binding site [chemical binding]; other site
1087448000307	Walker B motif; other site
1087448000308	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1087448000309	Integral membrane protein (PIN domain superfamily) [General function prediction only]; Region: COG4956
1087448000310	PIN domain of Thermus Thermophilus Hb8, uncharacterized Bacillus subtilis YacL, and other bacterial homologs; Region: PIN_YacL; cd09877
1087448000311	putative active site [active]
1087448000312	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1087448000313	substrate binding site; other site
1087448000314	dimer interface; other site
1087448000315	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
1087448000316	homotrimer interaction site [polypeptide binding]; other site
1087448000317	zinc binding site [ion binding]; other site
1087448000318	CDP-binding sites; other site
1087448000319	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1087448000320	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1087448000321	HIGH motif; other site
1087448000322	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1087448000323	active site
1087448000324	KMSKS motif; other site
1087448000325	Serine acetyltransferase [Amino acid transport and metabolism]; Region: CysE; COG1045
1087448000326	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1087448000327	trimer interface [polypeptide binding]; other site
1087448000328	active site
1087448000329	substrate binding site [chemical binding]; other site
1087448000330	CoA binding site [chemical binding]; other site
1087448000331	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1087448000332	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1087448000333	active site
1087448000334	HIGH motif; other site
1087448000335	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1087448000336	KMSKS motif; other site
1087448000337	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1087448000338	tRNA binding surface [nucleotide binding]; other site
1087448000339	anticodon binding site; other site
1087448000340	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1087448000341	active site
1087448000342	metal binding site [ion binding]; metal-binding site
1087448000343	dimerization interface [polypeptide binding]; other site
1087448000344	rRNA methylase, putative, group 3; Region: rRNA_methyl_3; TIGR00186
1087448000345	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1087448000346	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1087448000347	YacP-like NYN domain; Region: NYN_YacP; pfam05991
1087448000348	RNA polymerase factor sigma-70; Validated; Region: PRK08295
1087448000349	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1087448000350	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
1087448000351	50S ribosomal protein L33; Validated; Region: rpmG; PRK00504
1087448000352	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; pfam00584
1087448000353	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1087448000354	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1087448000355	putative homodimer interface [polypeptide binding]; other site
1087448000356	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1087448000357	heterodimer interface [polypeptide binding]; other site
1087448000358	homodimer interface [polypeptide binding]; other site
1087448000359	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1087448000360	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1087448000361	23S rRNA interface [nucleotide binding]; other site
1087448000362	L7/L12 interface [polypeptide binding]; other site
1087448000363	putative thiostrepton binding site; other site
1087448000364	L25 interface [polypeptide binding]; other site
1087448000365	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1087448000366	mRNA/rRNA interface [nucleotide binding]; other site
1087448000367	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1087448000368	23S rRNA interface [nucleotide binding]; other site
1087448000369	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1087448000370	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1087448000371	peripheral dimer interface [polypeptide binding]; other site
1087448000372	core dimer interface [polypeptide binding]; other site
1087448000373	L10 interface [polypeptide binding]; other site
1087448000374	L11 interface [polypeptide binding]; other site
1087448000375	putative EF-Tu interaction site [polypeptide binding]; other site
1087448000376	putative EF-G interaction site [polypeptide binding]; other site
1087448000377	16S RNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; Region: RsmC; COG2813
1087448000378	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1087448000379	S-adenosylmethionine binding site [chemical binding]; other site
1087448000380	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1087448000381	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1087448000382	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1087448000383	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1087448000384	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1087448000385	RPB10 interaction site [polypeptide binding]; other site
1087448000386	RPB1 interaction site [polypeptide binding]; other site
1087448000387	RPB11 interaction site [polypeptide binding]; other site
1087448000388	RPB3 interaction site [polypeptide binding]; other site
1087448000389	RPB12 interaction site [polypeptide binding]; other site
1087448000390	DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566
1087448000391	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1087448000392	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1087448000393	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1087448000394	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1087448000395	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1087448000396	Rpb1 (beta') - Rpb6 (omega) interaction site [polypeptide binding]; other site
1087448000397	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1087448000398	G-loop; other site
1087448000399	DNA binding site [nucleotide binding]
1087448000400	putative ribosomal protein L7Ae-like; Provisional; Region: PRK13602
1087448000401	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1087448000402	S17 interaction site [polypeptide binding]; other site
1087448000403	S8 interaction site; other site
1087448000404	16S rRNA interaction site [nucleotide binding]; other site
1087448000405	streptomycin interaction site [chemical binding]; other site
1087448000406	23S rRNA interaction site [nucleotide binding]; other site
1087448000407	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1087448000408	30S ribosomal protein S7; Validated; Region: PRK05302
1087448000409	elongation factor G; Reviewed; Region: PRK00007
1087448000410	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1087448000411	G1 box; other site
1087448000412	putative GEF interaction site [polypeptide binding]; other site
1087448000413	GTP/Mg2+ binding site [chemical binding]; other site
1087448000414	Switch I region; other site
1087448000415	G2 box; other site
1087448000416	G3 box; other site
1087448000417	Switch II region; other site
1087448000418	G4 box; other site
1087448000419	G5 box; other site
1087448000420	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1087448000421	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1087448000422	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1087448000423	elongation factor Tu; Reviewed; Region: PRK00049
1087448000424	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1087448000425	G1 box; other site
1087448000426	GEF interaction site [polypeptide binding]; other site
1087448000427	GTP/Mg2+ binding site [chemical binding]; other site
1087448000428	Switch I region; other site
1087448000429	G2 box; other site
1087448000430	G3 box; other site
1087448000431	Switch II region; other site
1087448000432	G4 box; other site
1087448000433	G5 box; other site
1087448000434	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1087448000435	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1087448000436	Antibiotic Binding Site [chemical binding]; other site
1087448000437	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1087448000438	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
1087448000439	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1087448000440	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1087448000441	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1087448000442	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1087448000443	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1087448000444	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1087448000445	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1087448000446	putative translocon binding site; other site
1087448000447	protein-rRNA interface [nucleotide binding]; other site
1087448000448	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1087448000449	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1087448000450	G-X-X-G motif; other site
1087448000451	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1087448000452	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1087448000453	23S rRNA interface [nucleotide binding]; other site
1087448000454	5S rRNA interface [nucleotide binding]; other site
1087448000455	putative antibiotic binding site [chemical binding]; other site
1087448000456	L25 interface [polypeptide binding]; other site
1087448000457	L27 interface [polypeptide binding]; other site
1087448000458	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1087448000459	23S rRNA interface [nucleotide binding]; other site
1087448000460	putative translocon interaction site; other site
1087448000461	signal recognition particle (SRP54) interaction site; other site
1087448000462	L23 interface [polypeptide binding]; other site
1087448000463	trigger factor interaction site; other site
1087448000464	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1087448000465	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1087448000466	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1087448000467	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1087448000468	RNA binding site [nucleotide binding]; other site
1087448000469	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1087448000470	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1087448000471	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1087448000472	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
1087448000473	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1087448000474	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1087448000475	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1087448000476	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1087448000477	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1087448000478	5S rRNA interface [nucleotide binding]; other site
1087448000479	L27 interface [polypeptide binding]; other site
1087448000480	23S rRNA interface [nucleotide binding]; other site
1087448000481	L5 interface [polypeptide binding]; other site
1087448000482	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1087448000483	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1087448000484	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1087448000485	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1087448000486	23S rRNA binding site [nucleotide binding]; other site
1087448000487	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1087448000488	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1087448000489	SecY translocase; Region: SecY; pfam00344
1087448000490	adenylate kinase; Reviewed; Region: adk; PRK00279
1087448000491	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1087448000492	AMP-binding site [chemical binding]; other site
1087448000493	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1087448000494	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1087448000495	active site
1087448000496	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1087448000497	rRNA binding site [nucleotide binding]; other site
1087448000498	predicted 30S ribosome binding site; other site
1087448000499	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1087448000500	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1087448000501	30S ribosomal protein S11; Validated; Region: PRK05309
1087448000502	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1087448000503	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1087448000504	alphaNTD - beta interaction site [polypeptide binding]; other site
1087448000505	alphaNTD homodimer interface [polypeptide binding]; other site
1087448000506	alphaNTD - beta' interaction site [polypeptide binding]; other site
1087448000507	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1087448000508	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
1087448000509	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13635
1087448000510	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1087448000511	Walker A/P-loop; other site
1087448000512	ATP binding site [chemical binding]; other site
1087448000513	Q-loop/lid; other site
1087448000514	ABC transporter signature motif; other site
1087448000515	Walker B; other site
1087448000516	D-loop; other site
1087448000517	H-loop/switch region; other site
1087448000518	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13634
1087448000519	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1087448000520	Walker A/P-loop; other site
1087448000521	ATP binding site [chemical binding]; other site
1087448000522	Q-loop/lid; other site
1087448000523	ABC transporter signature motif; other site
1087448000524	Walker B; other site
1087448000525	D-loop; other site
1087448000526	H-loop/switch region; other site
1087448000527	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
1087448000528	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
1087448000529	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1087448000530	dimerization interface 3.5A [polypeptide binding]; other site
1087448000531	active site
1087448000532	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1087448000533	23S rRNA interface [nucleotide binding]; other site
1087448000534	L3 interface [polypeptide binding]; other site
1087448000535	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1087448000536	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
1087448000537	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1087448000538	Domain of unknown function DUF59; Region: DUF59; pfam01883
1087448000539	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Mrp; COG0489
1087448000540	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1087448000541	Walker A motif; other site
1087448000542	KinB-signalling pathway activation in sporulation; Region: KbaA; pfam14089
1087448000543	Arginase family; Region: Arginase; cd09989
1087448000544	agmatinase; Region: agmatinase; TIGR01230
1087448000545	active site
1087448000546	Mn binding site [ion binding]; other site
1087448000547	oligomer interface [polypeptide binding]; other site
1087448000548	RNA polymerase sigma factor SigW; Provisional; Region: PRK09641
1087448000549	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1087448000550	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1087448000551	DNA binding residues [nucleotide binding]
1087448000552	Predicted transmembrane transcriptional regulator (anti-sigma factor) [Transcription]; Region: COG5662
1087448000553	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
1087448000554	Uncharacterized conserved protein [Function unknown]; Region: COG1624
1087448000555	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
1087448000556	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4856
1087448000557	YbbR-like protein; Region: YbbR; pfam07949
1087448000558	YbbR-like protein; Region: YbbR; pfam07949
1087448000559	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14316
1087448000560	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
1087448000561	active site
1087448000562	substrate binding site [chemical binding]; other site
1087448000563	metal binding site [ion binding]; metal-binding site
1087448000564	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
1087448000565	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1087448000566	glutaminase active site [active]
1087448000567	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1087448000568	dimer interface [polypeptide binding]; other site
1087448000569	active site
1087448000570	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1087448000571	dimer interface [polypeptide binding]; other site
1087448000572	active site
1087448000573	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220
1087448000574	Isochorismatase family; Region: Isochorismatase; pfam00857
1087448000575	catalytic triad [active]
1087448000576	conserved cis-peptide bond; other site
1087448000577	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1087448000578	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1087448000579	Coenzyme A binding pocket [chemical binding]; other site
1087448000580	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1087448000581	Predicted NAD/FAD-dependent oxidoreductase [General function prediction only]; Region: COG3380
1087448000582	Polyphosphate kinase 2 (PPK2); Region: PPK2; cl11971
1087448000583	Polyphosphate kinase 2 (PPK2); Region: PPK2; cl11971
1087448000584	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
1087448000585	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
1087448000586	PhnA protein; Region: PhnA; pfam03831
1087448000587	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1087448000588	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1087448000589	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1087448000590	ligand binding site [chemical binding]; other site
1087448000591	flexible hinge region; other site
1087448000592	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
1087448000593	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1087448000594	HAD superfamily (subfamily IA) hydrolase, TIGR02254; Region: YjjG/YfnB
1087448000595	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1087448000596	active site
1087448000597	motif I; other site
1087448000598	motif II; other site
1087448000599	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1087448000600	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1087448000601	Coenzyme A binding pocket [chemical binding]; other site
1087448000602	RNA polymerase sigma-70 factor, TIGR02954 family; Region: Sig70_famx3
1087448000603	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1087448000604	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1087448000605	DNA binding residues [nucleotide binding]
1087448000606	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
1087448000607	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1087448000608	Coenzyme A binding pocket [chemical binding]; other site
1087448000609	Dynamin family; Region: Dynamin_N; pfam00350
1087448000610	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
1087448000611	G1 box; other site
1087448000612	GTP/Mg2+ binding site [chemical binding]; other site
1087448000613	G2 box; other site
1087448000614	Switch I region; other site
1087448000615	G3 box; other site
1087448000616	Switch II region; other site
1087448000617	G4 box; other site
1087448000618	G5 box; other site
1087448000619	Uncharacterized protein/domain associated with GTPases [Function unknown]; Region: COG3597
1087448000620	Peroxiredoxin (PRX)-like 2 family; hypothetical proteins that show sequence similarity to PRXs. Members of this group contain a CXXC motif, similar to TRX. The second cysteine in the motif corresponds to the peroxidatic cysteine of PRX, however, these...; Region: PRX_like2; cd02970
1087448000621	putative catalytic residues [active]
1087448000622	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1087448000623	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1087448000624	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
1087448000625	Predicted metalloprotease [General function prediction only]; Region: COG2321
1087448000626	SnoaL-like domain; Region: SnoaL_2; pfam12680
1087448000627	Rrf2 family protein; Region: rrf2_super; TIGR00738
1087448000628	Transcriptional regulator; Region: Rrf2; pfam02082
1087448000629	ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion / Posttranslational modification, protein turnover, chaperones]; Region: CydC; COG4987
1087448000630	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1087448000631	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1087448000632	Walker A/P-loop; other site
1087448000633	ATP binding site [chemical binding]; other site
1087448000634	Q-loop/lid; other site
1087448000635	ABC transporter signature motif; other site
1087448000636	Walker B; other site
1087448000637	D-loop; other site
1087448000638	H-loop/switch region; other site
1087448000639	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1087448000640	Putative cyclase; Region: Cyclase; cl00814
1087448000641	tryptophan 2,3-dioxygenase; Region: trp_2_3_diox; TIGR03036
1087448000642	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
1087448000643	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1087448000644	kynureninase; Region: kynureninase; TIGR01814
1087448000645	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1087448000646	catalytic residue [active]
1087448000647	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1087448000648	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1087448000649	Domain of unknown function (DUF4385); Region: DUF4385; pfam14328
1087448000650	Electron transfer DM13; Region: DM13; pfam10517
1087448000651	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1087448000652	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1087448000653	putative substrate translocation pore; other site
1087448000654	Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism]; Region: NolL; COG3594
1087448000655	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1087448000656	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
1087448000657	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Region: Glyphos_transf; pfam04464
1087448000658	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1087448000659	substrate binding site; other site
1087448000660	dimer interface; other site
1087448000661	ribitol-5-phosphate dehydrogenase; Region: ribitol-5-phosphate_DH; cd08237
1087448000662	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1087448000663	putative NAD(P) binding site [chemical binding]; other site
1087448000664	putative catalytic Zn binding site [ion binding]; other site
1087448000665	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
1087448000666	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Region: Glyphos_transf; pfam04464
1087448000667	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
1087448000668	putative FMN binding site [chemical binding]; other site
1087448000669	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1087448000670	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1087448000671	metal binding site [ion binding]; metal-binding site
1087448000672	active site
1087448000673	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1087448000674	MarR family; Region: MarR; pfam01047
1087448000675	lysine transporter; Provisional; Region: PRK10836
1087448000676	methionine sulfoxide reductase A; Provisional; Region: PRK14054
1087448000677	methionine sulfoxide reductase B; Provisional; Region: PRK00222
1087448000678	SelR domain; Region: SelR; pfam01641
1087448000679	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4320
1087448000680	Uncharacterized protein conserved in bacteria (DUF2252); Region: DUF2252; pfam10009
1087448000681	amino acid transporter; Region: 2A0306; TIGR00909
1087448000682	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
1087448000683	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578
1087448000684	putative oxidoreductase; Provisional; Region: PRK11579
1087448000685	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1087448000686	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1087448000687	classical (c) SDRs; Region: SDR_c; cd05233
1087448000688	NAD(P) binding site [chemical binding]; other site
1087448000689	active site
1087448000690	Protein of unknown function, DUF393; Region: DUF393; cl01136
1087448000691	Staphylococcal nuclease homologue; Region: SNase; pfam00565
1087448000692	Cation efflux family; Region: Cation_efflux; pfam01545
1087448000693	glucose-1-dehydrogenase; Provisional; Region: PRK08936
1087448000694	glucose 1 dehydrogenase (GlcDH), classical (c) SDRs; Region: GlcDH_SDR_c; cd05358
1087448000695	NAD binding site [chemical binding]; other site
1087448000696	homodimer interface [polypeptide binding]; other site
1087448000697	active site
1087448000698	Putative glucose uptake permease [Carbohydrate transport and metabolism]; Region: GlcU; COG4975
1087448000699	ABC1 family; Region: ABC1; cl17513
1087448000700	Predicted unusual protein kinase [General function prediction only]; Region: AarF; COG0661
1087448000701	Predicted membrane protein [Function unknown]; Region: COG2860
1087448000702	UPF0126 domain; Region: UPF0126; pfam03458
1087448000703	UPF0126 domain; Region: UPF0126; pfam03458
1087448000704	Uncharacterized small membrane protein [Function unknown]; Region: COG2363
1087448000705	putative heme peroxidase; Provisional; Region: PRK12276
1087448000706	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
1087448000707	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1087448000708	active site
1087448000709	xanthine permease; Region: pbuX; TIGR03173
1087448000710	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
1087448000711	Spore germination protein; Region: Spore_permease; cl17796
1087448000712	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1087448000713	active site residue [active]
1087448000714	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cl00144
1087448000715	Cache domain; Region: Cache_1; pfam02743
1087448000716	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1087448000717	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1087448000718	dimerization interface [polypeptide binding]; other site
1087448000719	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1087448000720	dimer interface [polypeptide binding]; other site
1087448000721	putative CheW interface [polypeptide binding]; other site
1087448000722	Predicted membrane protein (DUF2157); Region: DUF2157; pfam09925
1087448000723	GDYXXLXY protein; Region: GDYXXLXY; pfam14345
1087448000724	putative GTP cyclohydrolase; Provisional; Region: PRK13674
1087448000725	integral membrane protein, YkoY family; Region: R_switched_YkoY; TIGR03716
1087448000726	integral membrane protein, YkoY family; Region: R_switched_YkoY; TIGR03716
1087448000727	HD domain; Region: HD_3; pfam13023
1087448000728	HD domain; Region: HD_3; cl17350
1087448000729	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
1087448000730	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1087448000731	putative substrate translocation pore; other site
1087448000732	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
1087448000733	Band_7_flotillin: a subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  These two proteins are lipid raft-associated.  Individual proteins of...; Region: Band_7_flotillin; cd03399
1087448000734	EDD domain protein, DegV family; Region: DegV; TIGR00762
1087448000735	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
1087448000736	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
1087448000737	HD superfamily phosphohydrolases [General function prediction only]; Region: COG1078
1087448000738	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1087448000739	Zn2+ binding site [ion binding]; other site
1087448000740	Mg2+ binding site [ion binding]; other site
1087448000741	Phosphotransferase enzyme family; Region: APH; pfam01636
1087448000742	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1087448000743	active site
1087448000744	ATP binding site [chemical binding]; other site
1087448000745	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
1087448000746	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
1087448000747	Nucleoside recognition; Region: Gate; pfam07670
1087448000748	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
1087448000749	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1087448000750	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1087448000751	NAD(P) binding site [chemical binding]; other site
1087448000752	active site
1087448000753	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cd00491
1087448000754	active site 1 [active]
1087448000755	dimer interface [polypeptide binding]; other site
1087448000756	hexamer interface [polypeptide binding]; other site
1087448000757	active site 2 [active]
1087448000758	YwhD family; Region: YwhD; pfam08741
1087448000759	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
1087448000760	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1087448000761	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1087448000762	phosphodiesterase YaeI; Provisional; Region: PRK11340
1087448000763	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
1087448000764	putative active site [active]
1087448000765	putative metal binding site [ion binding]; other site
1087448000766	BCCT family transporter; Region: BCCT; pfam02028
1087448000767	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
1087448000768	dimer interface [polypeptide binding]; other site
1087448000769	FMN binding site [chemical binding]; other site
1087448000770	spermidine synthase; Provisional; Region: PRK00811
1087448000771	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1087448000772	agmatinase; Region: agmatinase; TIGR01230
1087448000773	Agmatinase and related proteins; Region: Agmatinase-like_2; cd11593
1087448000774	putative active site [active]
1087448000775	Mn binding site [ion binding]; other site
1087448000776	Domain of unknown function (DUF4397); Region: DUF4397; pfam14344
1087448000777	Domain of unknown function (DUF4397); Region: DUF4397; pfam14344
1087448000778	Sortase E (SrtE) is a membrane transpeptidase found in gram-positive bacteria that cleaves surface proteins at a cell sorting motif and catalyzes a transpeptidation reaction in which the surface protein substrate is covalently linked to peptidoglycan for...; Region: Sortase_E; cd05829
1087448000779	active site
1087448000780	putative catalytic site [active]
1087448000781	superfamily containing globins and truncated hemoglobins; Region: globin_like; cl00280
1087448000782	heme-binding site [chemical binding]; other site
1087448000783	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1087448000784	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1087448000785	dimer interface [polypeptide binding]; other site
1087448000786	putative CheW interface [polypeptide binding]; other site
1087448000787	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1087448000788	metal-binding site [ion binding]
1087448000789	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1087448000790	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1087448000791	metal-binding site [ion binding]
1087448000792	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1087448000793	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1087448000794	Transcriptional regulators CsoR (copper-sensitive operon repressor), RcnR, and FrmR, and related domains; this domain superfamily was previously known as DUF156; Region: CsoR-like_DUF156; cd10148
1087448000795	putative homodimer interface [polypeptide binding]; other site
1087448000796	putative homotetramer interface [polypeptide binding]; other site
1087448000797	putative allosteric switch controlling residues; other site
1087448000798	putative metal binding site [ion binding]; other site
1087448000799	putative homodimer-homodimer interface [polypeptide binding]; other site
1087448000800	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1087448000801	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1087448000802	putative substrate translocation pore; other site
1087448000803	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1087448000804	bacillithiol system protein YtxJ; Region: B_thiol_YtxJ; TIGR04019
1087448000805	acetolactate synthase; Reviewed; Region: PRK08322
1087448000806	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1087448000807	PYR/PP interface [polypeptide binding]; other site
1087448000808	dimer interface [polypeptide binding]; other site
1087448000809	TPP binding site [chemical binding]; other site
1087448000810	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1087448000811	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
1087448000812	TPP-binding site [chemical binding]; other site
1087448000813	succinic semialdehyde dehydrogenase; Region: PLN02278
1087448000814	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
1087448000815	tetramerization interface [polypeptide binding]; other site
1087448000816	NAD(P) binding site [chemical binding]; other site
1087448000817	catalytic residues [active]
1087448000818	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
1087448000819	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1087448000820	Ca binding site [ion binding]; other site
1087448000821	active site
1087448000822	catalytic site [active]
1087448000823	Domain of unknown function (DUF1934); Region: DUF1934; pfam09148
1087448000824	Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR9; cd08274
1087448000825	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1087448000826	putative NAD(P) binding site [chemical binding]; other site
1087448000827	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1087448000828	4Fe-4S binding domain; Region: Fer4; cl02805
1087448000829	Cysteine-rich domain; Region: CCG; pfam02754
1087448000830	Cysteine-rich domain; Region: CCG; pfam02754
1087448000831	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
1087448000832	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1087448000833	DNA binding residues [nucleotide binding]
1087448000834	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1087448000835	Domain of unknown function DUF21; Region: DUF21; pfam01595
1087448000836	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1087448000837	Transporter associated domain; Region: CorC_HlyC; smart01091
1087448000838	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1087448000839	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
1087448000840	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1087448000841	ATP binding site [chemical binding]; other site
1087448000842	Mg2+ binding site [ion binding]; other site
1087448000843	G-X-G motif; other site
1087448000844	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
1087448000845	active site
1087448000846	catalytic residues [active]
1087448000847	EDD domain protein, DegV family; Region: DegV; TIGR00762
1087448000848	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
1087448000849	CrcB-like protein; Region: CRCB; cl09114
1087448000850	CrcB-like protein; Region: CRCB; cl09114
1087448000851	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1087448000852	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1087448000853	dimer interface [polypeptide binding]; other site
1087448000854	putative CheW interface [polypeptide binding]; other site
1087448000855	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1087448000856	alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases; Region: MDR_like_2; cd05289
1087448000857	putative NAD(P) binding site [chemical binding]; other site
1087448000858	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
1087448000859	active site
1087448000860	NTP binding site [chemical binding]; other site
1087448000861	metal binding triad [ion binding]; metal-binding site
1087448000862	antibiotic binding site [chemical binding]; other site
1087448000863	Predicted transcriptional regulators [Transcription]; Region: COG1733
1087448000864	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1087448000865	Predicted ring-cleavage extradiol dioxygenase [General function prediction only]; Region: COG2514
1087448000866	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_12; cd07255
1087448000867	putative metal binding site [ion binding]; other site
1087448000868	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
1087448000869	active site
1087448000870	NIPSNAP; Region: NIPSNAP; pfam07978
1087448000871	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
1087448000872	nudix motif; other site
1087448000873	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1087448000874	Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182
1087448000875	PepSY-associated TM helix; Region: PepSY_TM_1; pfam13172
1087448000876	PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703
1087448000877	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1087448000878	yrhL-like subfamily of SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_yrhL_like; cd01840
1087448000879	catalytic triad [active]
1087448000880	catalytic triad [active]
1087448000881	oxyanion hole [active]
1087448000882	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Ada; COG2169
1087448000883	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
1087448000884	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1087448000885	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1087448000886	DNA binding site [nucleotide binding]
1087448000887	active site
1087448000888	DNA alkylation repair enzyme [DNA replication, recombination, and repair]; Region: COG4335
1087448000889	AAA domain; Region: AAA_18; pfam13238
1087448000890	AAA domain; Region: AAA_17; pfam13207
1087448000891	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1087448000892	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1087448000893	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1087448000894	metal binding site [ion binding]; metal-binding site
1087448000895	active site
1087448000896	I-site; other site
1087448000897	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
1087448000898	DNA/RNA non-specific endonuclease; Region: Endonuclea_NS_2; cl17626
1087448000899	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_39; cd04699
1087448000900	nudix motif; other site
1087448000901	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E_like proteins; Region: GAT1_Peptidase_E_like; cd03129
1087448000902	catalytic triad [active]
1087448000903	active site nucleophile [active]
1087448000904	Predicted permease; Region: DUF318; cl17795
1087448000905	Predicted transcriptional regulators [Transcription]; Region: COG1695
1087448000906	Transcriptional regulator PadR-like family; Region: PadR; cl17335
1087448000907	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1087448000908	homotrimer interaction site [polypeptide binding]; other site
1087448000909	putative active site [active]
1087448000910	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in a group of uncharacterized proteins from archaea and bacteria; Region: NTP-PPase_COG4997; cd11532
1087448000911	metal binding site [ion binding]; metal-binding site
1087448000912	N-terminal putative catalytic domain of uncharacterized prokaryotic and archeal HKD family nucleases fused to a DEAD/DEAH box helicase domain; Region: PLDc_N_DEXD_b3; cd09205
1087448000913	PLD-like domain; Region: PLDc_2; pfam13091
1087448000914	putative homodimer interface [polypeptide binding]; other site
1087448000915	putative active site [active]
1087448000916	catalytic site [active]
1087448000917	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
1087448000918	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1087448000919	ATP binding site [chemical binding]; other site
1087448000920	putative Mg++ binding site [ion binding]; other site
1087448000921	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1087448000922	nucleotide binding region [chemical binding]; other site
1087448000923	ATP-binding site [chemical binding]; other site
1087448000924	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
1087448000925	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1087448000926	dimer interface [polypeptide binding]; other site
1087448000927	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1087448000928	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1087448000929	DNA binding site [nucleotide binding]
1087448000930	domain linker motif; other site
1087448000931	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1087448000932	dimerization interface [polypeptide binding]; other site
1087448000933	ligand binding site [chemical binding]; other site
1087448000934	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1087448000935	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
1087448000936	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
1087448000937	beta-galactosidase; Region: BGL; TIGR03356
1087448000938	Laminarinase, member of the glycosyl hydrolase family 16; Region: GH16_laminarinase_like; cd08023
1087448000939	active site
1087448000940	catalytic residues [active]
1087448000941	Carbohydrate binding domain; Region: CBM_4_9; pfam02018
1087448000942	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1087448000943	Peptidase family M28; Region: Peptidase_M28; pfam04389
1087448000944	metal binding site [ion binding]; metal-binding site
1087448000945	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1087448000946	metal binding site [ion binding]; metal-binding site
1087448000947	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1087448000948	binding surface
1087448000949	TPR motif; other site
1087448000950	Excalibur calcium-binding domain; Region: Excalibur; cl05460
1087448000951	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1087448000952	catalytic residues [active]
1087448000953	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1087448000954	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
1087448000955	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1087448000956	S-adenosylmethionine binding site [chemical binding]; other site
1087448000957	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1087448000958	MarR family; Region: MarR_2; pfam12802
1087448000959	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1087448000960	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1087448000961	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1087448000962	Walker A/P-loop; other site
1087448000963	ATP binding site [chemical binding]; other site
1087448000964	Q-loop/lid; other site
1087448000965	ABC transporter signature motif; other site
1087448000966	Walker B; other site
1087448000967	D-loop; other site
1087448000968	H-loop/switch region; other site
1087448000969	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1087448000970	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1087448000971	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
1087448000972	Walker A/P-loop; other site
1087448000973	ATP binding site [chemical binding]; other site
1087448000974	Q-loop/lid; other site
1087448000975	ABC transporter signature motif; other site
1087448000976	Walker B; other site
1087448000977	D-loop; other site
1087448000978	H-loop/switch region; other site
1087448000979	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1087448000980	active site residue [active]
1087448000981	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
1087448000982	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1087448000983	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1087448000984	active site residue [active]
1087448000985	Conserved TM helix; Region: TM_helix; pfam05552
1087448000986	Conserved TM helix; Region: TM_helix; pfam05552
1087448000987	amino acid transporter; Region: 2A0306; TIGR00909
1087448000988	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
1087448000989	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1087448000990	Coenzyme A binding pocket [chemical binding]; other site
1087448000991	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_18; cd04677
1087448000992	nudix motif; other site
1087448000993	Nitric oxide synthase (NOS) produces nitric oxide (NO) by catalyzing a five-electron heme-based oxidation of a guanidine nitrogen of L-arginine to L-citrulline via two successive monooxygenation reactions producing N(omega)-hydroxy-L-arginine (NHA) as an...; Region: NOS_oxygenase; cd00575
1087448000994	active site
1087448000995	dimer interface [polypeptide binding]; other site
1087448000996	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
1087448000997	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1087448000998	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1087448000999	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1087448001000	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1087448001001	dimerization interface [polypeptide binding]; other site
1087448001002	Uncharacterized protein YrkD from Bacillus subtilis and related domains; this domain superfamily was previously known as part of DUF156; Region: BsYrkD-like_DUF156; cd10155
1087448001003	putative homodimer interface [polypeptide binding]; other site
1087448001004	putative homotetramer interface [polypeptide binding]; other site
1087448001005	putative metal binding site [ion binding]; other site
1087448001006	putative homodimer-homodimer interface [polypeptide binding]; other site
1087448001007	putative allosteric switch controlling residues; other site
1087448001008	DsrE/DsrF/DrsH-like family; Region: DrsE_2; pfam13686
1087448001009	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1087448001010	active site residue [active]
1087448001011	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1087448001012	active site residue [active]
1087448001013	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291
1087448001014	CPxP  motif; other site
1087448001015	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1087448001016	active site residue [active]
1087448001017	Member of the Rhodanese Homology Domain superfamily. This CD includes predicted proteins with rhodanese-like domains found N-terminal of the metallo-beta-lactamase domain; Region: RHOD_Lact_B; cd01523
1087448001018	active site residue [active]
1087448001019	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1087448001020	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291
1087448001021	CPxP  motif; other site
1087448001022	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1087448001023	Domain of unknown function DUF302; Region: DUF302; cl01364
1087448001024	methionine sulfoxide reductase A; Provisional; Region: PRK14054
1087448001025	methionine sulfoxide reductase B; Provisional; Region: PRK00222
1087448001026	SelR domain; Region: SelR; pfam01641
1087448001027	Peptidase S8 family domain in Thermitase-like proteins; Region: Peptidases_S8_Thermitase_like; cd07484
1087448001028	active site
1087448001029	catalytic triad [active]
1087448001030	GAF domain; Region: GAF_3; pfam13492
1087448001031	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
1087448001032	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1087448001033	dimer interface [polypeptide binding]; other site
1087448001034	phosphorylation site [posttranslational modification]
1087448001035	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1087448001036	ATP binding site [chemical binding]; other site
1087448001037	Mg2+ binding site [ion binding]; other site
1087448001038	G-X-G motif; other site
1087448001039	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1087448001040	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1087448001041	metal binding site [ion binding]; metal-binding site
1087448001042	active site
1087448001043	I-site; other site
1087448001044	Heat induced stress protein YflT; Region: YflT; pfam11181
1087448001045	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1087448001046	Ligand Binding Site [chemical binding]; other site
1087448001047	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1087448001048	MarR family; Region: MarR_2; pfam12802
1087448001049	Transport protein; Region: actII; TIGR00833
1087448001050	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1087448001051	MarR family; Region: MarR_2; pfam12802
1087448001052	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1087448001053	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1087448001054	nucleotide binding site [chemical binding]; other site
1087448001055	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1087448001056	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1087448001057	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1087448001058	dimer interface [polypeptide binding]; other site
1087448001059	conserved gate region; other site
1087448001060	putative PBP binding loops; other site
1087448001061	ABC-ATPase subunit interface; other site
1087448001062	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1087448001063	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1087448001064	dimer interface [polypeptide binding]; other site
1087448001065	conserved gate region; other site
1087448001066	putative PBP binding loops; other site
1087448001067	ABC-ATPase subunit interface; other site
1087448001068	Beta-galactosidase [Carbohydrate transport and metabolism]; Region: LacA; COG1874
1087448001069	Beta-galactosidase; Region: Glyco_hydro_42; pfam02449
1087448001070	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
1087448001071	Beta-galactosidase C-terminal domain; Region: Glyco_hydro_42C; pfam08533
1087448001072	Alpha-galactosidase [Carbohydrate transport and metabolism]; Region: GalA; COG3345
1087448001073	Melibiase; Region: Melibiase; pfam02065
1087448001074	galactokinase; Provisional; Region: PRK05322
1087448001075	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
1087448001076	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1087448001077	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1087448001078	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
1087448001079	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1087448001080	NAD binding site [chemical binding]; other site
1087448001081	homodimer interface [polypeptide binding]; other site
1087448001082	active site
1087448001083	substrate binding site [chemical binding]; other site
1087448001084	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK05270
1087448001085	Galactose-1-phosphate uridyl transferase, N-terminal domain; Region: GalP_UDP_transf; pfam01087
1087448001086	Galactose-1-phosphate uridyl transferase, C-terminal domain; Region: GalP_UDP_tr_C; pfam02744
1087448001087	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
1087448001088	active site
1087448001089	catalytic residues [active]
1087448001090	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1087448001091	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1087448001092	DNA binding site [nucleotide binding]
1087448001093	active site
1087448001094	dihydrolipoamide dehydrogenase; Region: lipoamide_DH; TIGR01350
1087448001095	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
1087448001096	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1087448001097	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1087448001098	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
1087448001099	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1087448001100	E3 interaction surface; other site
1087448001101	lipoyl attachment site [posttranslational modification]; other site
1087448001102	e3 binding domain; Region: E3_binding; pfam02817
1087448001103	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1087448001104	Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Region: TPP_enzyme_PYR; cl11410
1087448001105	PYR/PP interface [polypeptide binding]; other site
1087448001106	dimer interface [polypeptide binding]; other site
1087448001107	TPP binding site [chemical binding]; other site
1087448001108	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1087448001109	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_x; TIGR03181
1087448001110	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
1087448001111	TPP-binding site [chemical binding]; other site
1087448001112	tetramer interface [polypeptide binding]; other site
1087448001113	heterodimer interface [polypeptide binding]; other site
1087448001114	phosphorylation loop region [posttranslational modification]
1087448001115	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1087448001116	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Region: ELFV_dehydrog; pfam00208
1087448001117	NAD(P) binding domain of leucine dehydrogenase, phenylalanine dehydrogenase, and valine dehydrogenase; Region: NAD_bind_Leu_Phe_Val_DH; cd01075
1087448001118	NAD binding site [chemical binding]; other site
1087448001119	Phe binding site; other site
1087448001120	Predicted thioesterase [General function prediction only]; Region: COG5496
1087448001121	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1087448001122	phenylacetate-CoA ligase; Region: PA_CoA_ligase; TIGR02155
1087448001123	acyl-activating enzyme (AAE) consensus motif; other site
1087448001124	AMP binding site [chemical binding]; other site
1087448001125	active site
1087448001126	CoA binding site [chemical binding]; other site
1087448001127	phenylacetate-CoA oxygenase subunit PaaA; Provisional; Region: paaA; PRK13778
1087448001128	phenylacetate-CoA oxygenase, PaaG subunit; Region: PA_CoA_Oxy1; TIGR02156
1087448001129	Phenylacetic acid degradation B; Region: PaaB; cl01371
1087448001130	Phenylacetic acid catabolic protein; Region: PaaA_PaaC; pfam05138
1087448001131	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
1087448001132	phenylacetate-CoA oxygenase, PaaJ subunit; Region: PA_CoA_Oxy4; TIGR02159
1087448001133	EthD domain; Region: EthD; cl17553
1087448001134	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1087448001135	enoyl-CoA hydratase; Provisional; Region: PRK05862
1087448001136	substrate binding site [chemical binding]; other site
1087448001137	oxyanion hole (OAH) forming residues; other site
1087448001138	trimer interface [polypeptide binding]; other site
1087448001139	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
1087448001140	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1087448001141	NAD(P) binding site [chemical binding]; other site
1087448001142	catalytic residues [active]
1087448001143	3-hydroxybutyryl-CoA dehydrogenase; Validated; Region: PRK09260
1087448001144	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1087448001145	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1087448001146	beta-ketoadipyl CoA thiolase; Validated; Region: PRK09050
1087448001147	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1087448001148	dimer interface [polypeptide binding]; other site
1087448001149	active site
1087448001150	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1087448001151	enoyl-CoA hydratase; Provisional; Region: PRK07657
1087448001152	substrate binding site [chemical binding]; other site
1087448001153	oxyanion hole (OAH) forming residues; other site
1087448001154	trimer interface [polypeptide binding]; other site
1087448001155	Phenylacetic acid-responsive transcriptional repressor [Transcription]; Region: PaaX; COG3327
1087448001156	PaaX-like protein; Region: PaaX; pfam07848
1087448001157	PaaX-like protein C-terminal domain; Region: PaaX_C; pfam08223
1087448001158	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
1087448001159	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
1087448001160	trimer interface [polypeptide binding]; other site
1087448001161	putative metal binding site [ion binding]; other site
1087448001162	putative enoyl-[acyl-carrier-protein] reductase II; Region: enACPred_II; TIGR03151
1087448001163	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
1087448001164	FMN binding site [chemical binding]; other site
1087448001165	substrate binding site [chemical binding]; other site
1087448001166	putative catalytic residue [active]
1087448001167	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1087448001168	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1087448001169	methionine sulfoxide reductase A; Provisional; Region: PRK14054
1087448001170	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1087448001171	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1087448001172	NlpC/P60 family; Region: NLPC_P60; pfam00877
1087448001173	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1087448001174	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1087448001175	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1087448001176	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
1087448001177	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
1087448001178	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1087448001179	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1087448001180	active site
1087448001181	catalytic tetrad [active]
1087448001182	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
1087448001183	Iron-containing alcohol dehydrogenase; Region: Fe-ADH; pfam00465
1087448001184	putative active site [active]
1087448001185	metal binding site [ion binding]; metal-binding site
1087448001186	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1087448001187	Protein of unknown function (DUF1294); Region: DUF1294; pfam06961
1087448001188	Repair protein; Region: Repair_PSII; pfam04536
1087448001189	Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704
1087448001190	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
1087448001191	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1087448001192	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1087448001193	metal-binding site [ion binding]
1087448001194	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1087448001195	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1087448001196	Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]; Region: COG0428
1087448001197	YolD-like protein; Region: YolD; pfam08863
1087448001198	DNA polymerase IV; Reviewed; Region: PRK03103
1087448001199	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1087448001200	active site
1087448001201	DNA binding site [nucleotide binding]
1087448001202	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1087448001203	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1087448001204	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
1087448001205	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1087448001206	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
1087448001207	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
1087448001208	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1087448001209	Coenzyme A binding pocket [chemical binding]; other site
1087448001210	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1791
1087448001211	Cupin domain; Region: Cupin_2; pfam07883
1087448001212	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cl00214
1087448001213	intersubunit interface [polypeptide binding]; other site
1087448001214	active site
1087448001215	Zn2+ binding site [ion binding]; other site
1087448001216	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
1087448001217	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1087448001218	motif II; other site
1087448001219	2,3-diketo-5-methylthiopentyl-1-phosphate enolase; Reviewed; Region: mtnW; PRK09549
1087448001220	2,3-diketo-5-methylthiopentyl-1-phosphate enolase; Region: RLP_DK-MTP-1-P-enolase; cd08209
1087448001221	dimer interface [polypeptide binding]; other site
1087448001222	active site
1087448001223	catalytic residue [active]
1087448001224	metal binding site [ion binding]; metal-binding site
1087448001225	methylthioribose kinase; Reviewed; Region: mtnK; PRK09550
1087448001226	Phosphotransferase enzyme family; Region: APH; pfam01636
1087448001227	methylthioribose-1-phosphate isomerase; Reviewed; Region: mtnA; PRK05720
1087448001228	S-methyl-5-thioribose-1-phosphate isomerase; Region: salvage_mtnA; TIGR00512
1087448001229	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1087448001230	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1087448001231	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1087448001232	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1087448001233	Walker A/P-loop; other site
1087448001234	ATP binding site [chemical binding]; other site
1087448001235	Q-loop/lid; other site
1087448001236	ABC transporter signature motif; other site
1087448001237	Walker B; other site
1087448001238	D-loop; other site
1087448001239	H-loop/switch region; other site
1087448001240	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1087448001241	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1087448001242	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1087448001243	TM-ABC transporter signature motif; other site
1087448001244	MoxR-like ATPases [General function prediction only]; Region: COG0714
1087448001245	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1087448001246	Walker A motif; other site
1087448001247	ATP binding site [chemical binding]; other site
1087448001248	Walker B motif; other site
1087448001249	arginine finger; other site
1087448001250	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
1087448001251	Protein of unknown function DUF58; Region: DUF58; pfam01882
1087448001252	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
1087448001253	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
1087448001254	Domain of unknown function (DUF4129); Region: DUF4129; pfam13559
1087448001255	GMP synthase; Reviewed; Region: guaA; PRK00074
1087448001256	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1087448001257	AMP/PPi binding site [chemical binding]; other site
1087448001258	candidate oxyanion hole; other site
1087448001259	catalytic triad [active]
1087448001260	potential glutamine specificity residues [chemical binding]; other site
1087448001261	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1087448001262	ATP Binding subdomain [chemical binding]; other site
1087448001263	Ligand Binding sites [chemical binding]; other site
1087448001264	Dimerization subdomain; other site
1087448001265	Heat induced stress protein YflT; Region: YflT; pfam11181
1087448001266	Domain of unknown function (DUF2382); Region: DUF2382; pfam09557
1087448001267	Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism]; Region: NolL; COG3594
1087448001268	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1087448001269	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1087448001270	Proline dehydrogenase; Region: Pro_dh; cl03282
1087448001271	NETI protein; Region: NETI; pfam14044
1087448001272	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
1087448001273	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
1087448001274	ATP-grasp domain; Region: ATP-grasp; pfam02222
1087448001275	adenylosuccinate lyase; Provisional; Region: PRK07492
1087448001276	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
1087448001277	tetramer interface [polypeptide binding]; other site
1087448001278	active site
1087448001279	Adenylosuccinate lyase C-terminus; Region: ADSL_C; pfam10397
1087448001280	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
1087448001281	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
1087448001282	ATP binding site [chemical binding]; other site
1087448001283	active site
1087448001284	substrate binding site [chemical binding]; other site
1087448001285	phosphoribosylformylglycinamidine synthase subunit PurS; Reviewed; Region: PRK05974
1087448001286	phosphoribosylformylglycinamidine synthase I; Provisional; Region: PRK03619
1087448001287	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
1087448001288	putative active site [active]
1087448001289	catalytic triad [active]
1087448001290	phosphoribosylformylglycinamidine synthase II; Provisional; Region: PRK01213
1087448001291	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
1087448001292	dimerization interface [polypeptide binding]; other site
1087448001293	ATP binding site [chemical binding]; other site
1087448001294	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
1087448001295	dimerization interface [polypeptide binding]; other site
1087448001296	ATP binding site [chemical binding]; other site
1087448001297	amidophosphoribosyltransferase; Provisional; Region: PRK07631
1087448001298	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
1087448001299	active site
1087448001300	tetramer interface [polypeptide binding]; other site
1087448001301	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1087448001302	active site
1087448001303	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
1087448001304	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
1087448001305	dimerization interface [polypeptide binding]; other site
1087448001306	putative ATP binding site [chemical binding]; other site
1087448001307	phosphoribosylglycinamide formyltransferase; Reviewed; Region: purN; PRK05647
1087448001308	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
1087448001309	active site
1087448001310	substrate binding site [chemical binding]; other site
1087448001311	cosubstrate binding site; other site
1087448001312	catalytic site [active]
1087448001313	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
1087448001314	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
1087448001315	purine monophosphate binding site [chemical binding]; other site
1087448001316	dimer interface [polypeptide binding]; other site
1087448001317	putative catalytic residues [active]
1087448001318	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
1087448001319	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
1087448001320	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
1087448001321	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1087448001322	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
1087448001323	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1087448001324	Adenine deaminase [Nucleotide transport and metabolism]; Region: AdeC; COG1001
1087448001325	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1087448001326	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1087448001327	active site
1087448001328	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
1087448001329	Trp repressor protein; Region: Trp_repressor; cl17266
1087448001330	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
1087448001331	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
1087448001332	PcrB family; Region: PcrB; pfam01884
1087448001333	PcrB_like proteins. One member of this family, a protein from Archaeoglobus fulgidus, has been characterized as a (S)-3-O-geranylgeranylglyceryl phosphate synthase (AfGGGPS). AfGGGPS catalyzes the formation of an ether linkage between...; Region: PcrB_like; cd02812
1087448001334	substrate binding site [chemical binding]; other site
1087448001335	putative active site [active]
1087448001336	dimer interface [polypeptide binding]; other site
1087448001337	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
1087448001338	Part of AAA domain; Region: AAA_19; pfam13245
1087448001339	Family description; Region: UvrD_C_2; pfam13538
1087448001340	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1087448001341	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1087448001342	nucleotide binding pocket [chemical binding]; other site
1087448001343	K-X-D-G motif; other site
1087448001344	catalytic site [active]
1087448001345	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1087448001346	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
1087448001347	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1087448001348	Dimer interface [polypeptide binding]; other site
1087448001349	BRCT sequence motif; other site
1087448001350	Sortases are cysteine transpeptidases, found in gram-positive bacteria, that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the surface protein substrate is...; Region: Sortase; cl09098
1087448001351	active site
1087448001352	catalytic site [active]
1087448001353	Protein involved in sex pheromone biosynthesis [General function prediction only]; Region: CamS; COG4851
1087448001354	N-terminal repeat domain of CamS sex pheromone cAM373 precursor; Region: CamS_repeat_1; cd13441
1087448001355	putative dimer interface [polypeptide binding]; other site
1087448001356	C-terminal repeat domain of CamS sex pheromone cAM373 precursor; Region: CamS_repeat_2; cd13440
1087448001357	putative dimer interface [polypeptide binding]; other site
1087448001358	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1087448001359	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1087448001360	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1087448001361	putative active site [active]
1087448001362	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1087448001363	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
1087448001364	metal binding site [ion binding]; metal-binding site
1087448001365	dimer interface [polypeptide binding]; other site
1087448001366	Uncharacterized conserved protein (DUF2196); Region: DUF2196; pfam09962
1087448001367	chaperone protein DnaJ; Provisional; Region: PRK14299
1087448001368	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1087448001369	HSP70 interaction site [polypeptide binding]; other site
1087448001370	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1087448001371	dimer interface [polypeptide binding]; other site
1087448001372	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
1087448001373	Clp amino terminal domain; Region: Clp_N; pfam02861
1087448001374	Clp amino terminal domain; Region: Clp_N; pfam02861
1087448001375	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1087448001376	Walker A motif; other site
1087448001377	ATP binding site [chemical binding]; other site
1087448001378	Walker B motif; other site
1087448001379	arginine finger; other site
1087448001380	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1087448001381	Walker A motif; other site
1087448001382	ATP binding site [chemical binding]; other site
1087448001383	Walker B motif; other site
1087448001384	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1087448001385	Glutaminase [Amino acid transport and metabolism]; Region: GlsA; COG2066
1087448001386	glutaminase A; Region: Gln_ase; TIGR03814
1087448001387	CHAD domain; Region: CHAD; pfam05235
1087448001388	multidrug efflux protein; Reviewed; Region: PRK01766
1087448001389	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
1087448001390	cation binding site [ion binding]; other site
1087448001391	Predicted integral membrane protein [Function unknown]; Region: COG0392
1087448001392	Uncharacterized conserved protein [Function unknown]; Region: COG2898
1087448001393	Uncharacterized conserved protein (DUF2156); Region: DUF2156; pfam09924
1087448001394	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
1087448001395	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1087448001396	active site
1087448001397	dimer interface [polypeptide binding]; other site
1087448001398	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1087448001399	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1087448001400	active site
1087448001401	trimer interface [polypeptide binding]; other site
1087448001402	allosteric site; other site
1087448001403	active site lid [active]
1087448001404	Transcriptional regulator [Transcription]; Region: LytR; COG1316
1087448001405	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1087448001406	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1087448001407	DNA-binding site [nucleotide binding]; DNA binding site
1087448001408	UTRA domain; Region: UTRA; pfam07702
1087448001409	Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain [General function prediction only]; Region: COG2872
1087448001410	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1087448001411	Acetyltransferase (GNAT) domain; Region: Acetyltransf_5; pfam13444
1087448001412	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1087448001413	Coenzyme A binding pocket [chemical binding]; other site
1087448001414	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1087448001415	argininosuccinate synthase; Provisional; Region: PRK13820
1087448001416	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
1087448001417	ANP binding site [chemical binding]; other site
1087448001418	Substrate Binding Site II [chemical binding]; other site
1087448001419	Substrate Binding Site I [chemical binding]; other site
1087448001420	argininosuccinate lyase; Provisional; Region: PRK00855
1087448001421	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
1087448001422	active sites [active]
1087448001423	tetramer interface [polypeptide binding]; other site
1087448001424	aspartate kinase; Reviewed; Region: PRK06635
1087448001425	AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily (AAK), AKii; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis 168, and the lysine plus threonine-sensitive...; Region: AAK_AKii-LysC-BS; cd04261
1087448001426	putative nucleotide binding site [chemical binding]; other site
1087448001427	putative catalytic residues [active]
1087448001428	putative Mg ion binding site [ion binding]; other site
1087448001429	putative aspartate binding site [chemical binding]; other site
1087448001430	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII and related proteins; Region: ACT_AK-LysC-DapG-like_1; cd04891
1087448001431	ACT domains of the lysine-sensitive, aspartokinase (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AKii-LysC-BS-like_2; cd04936
1087448001432	putative allosteric regulatory residue; other site
1087448001433	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
1087448001434	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1087448001435	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1087448001436	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1087448001437	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1087448001438	dimer interface [polypeptide binding]; other site
1087448001439	active site
1087448001440	catalytic residue [active]
1087448001441	dihydrodipicolinate reductase; Provisional; Region: PRK00048
1087448001442	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1087448001443	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1087448001444	Tetrahydrodipicolinate succinyltransferase N-terminal; Region: DapH_N; pfam08503
1087448001445	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Region: DapD_Ac; TIGR03532
1087448001446	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
1087448001447	trimer interface [polypeptide binding]; other site
1087448001448	active site
1087448001449	substrate binding site [chemical binding]; other site
1087448001450	CoA binding site [chemical binding]; other site
1087448001451	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1087448001452	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
1087448001453	homodimer interface [polypeptide binding]; other site
1087448001454	substrate-cofactor binding pocket; other site
1087448001455	catalytic residue [active]
1087448001456	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
1087448001457	active site
1087448001458	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1087448001459	Alanine racemase [Cell envelope biogenesis, outer membrane]; Region: Alr; COG0787
1087448001460	dimer interface [polypeptide binding]; other site
1087448001461	substrate binding site [chemical binding]; other site
1087448001462	catalytic residues [active]
1087448001463	diaminopimelate decarboxylase; Region: lysA; TIGR01048
1087448001464	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1087448001465	active site
1087448001466	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1087448001467	substrate binding site [chemical binding]; other site
1087448001468	catalytic residues [active]
1087448001469	dimer interface [polypeptide binding]; other site
1087448001470	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1087448001471	Catalytic NodB homology domain of rhizobial NodB-like proteins; Region: CE4_NodB_like_6s_7s; cd10917
1087448001472	NodB motif; other site
1087448001473	active site
1087448001474	catalytic site [active]
1087448001475	metal binding site [ion binding]; metal-binding site
1087448001476	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1087448001477	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1087448001478	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1087448001479	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
1087448001480	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
1087448001481	Walker A/P-loop; other site
1087448001482	ATP binding site [chemical binding]; other site
1087448001483	Q-loop/lid; other site
1087448001484	ABC transporter signature motif; other site
1087448001485	Walker B; other site
1087448001486	D-loop; other site
1087448001487	H-loop/switch region; other site
1087448001488	FOG: CBS domain [General function prediction only]; Region: COG0517
1087448001489	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
1087448001490	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1087448001491	dimer interface [polypeptide binding]; other site
1087448001492	conserved gate region; other site
1087448001493	putative PBP binding loops; other site
1087448001494	ABC-ATPase subunit interface; other site
1087448001495	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
1087448001496	ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; cl17891
1087448001497	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
1087448001498	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
1087448001499	trimer interface [polypeptide binding]; other site
1087448001500	putative metal binding site [ion binding]; other site
1087448001501	Adenine deaminase [Nucleotide transport and metabolism]; Region: AdeC; COG1001
1087448001502	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1087448001503	Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295
1087448001504	active site
1087448001505	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
1087448001506	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1087448001507	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1087448001508	peptide binding site [polypeptide binding]; other site
1087448001509	MgtC family; Region: MgtC; pfam02308
1087448001510	arginine-ornithine antiporter; Region: arg_ornith_anti; TIGR03810
1087448001511	PAS fold; Region: PAS; pfam00989
1087448001512	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1087448001513	putative active site [active]
1087448001514	heme pocket [chemical binding]; other site
1087448001515	PAS domain; Region: PAS_9; pfam13426
1087448001516	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1087448001517	putative active site [active]
1087448001518	heme pocket [chemical binding]; other site
1087448001519	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1087448001520	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1087448001521	metal binding site [ion binding]; metal-binding site
1087448001522	active site
1087448001523	I-site; other site
1087448001524	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1087448001525	ornithine--oxo-acid transaminase; Provisional; Region: rocD; PRK04073
1087448001526	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1087448001527	inhibitor-cofactor binding pocket; inhibition site
1087448001528	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1087448001529	catalytic residue [active]
1087448001530	CsbD-like; Region: CsbD; pfam05532
1087448001531	PTS system, N-acetylglucosamine-specific IIBC component; Region: PTS-II-BC-nag; TIGR01998
1087448001532	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1087448001533	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1087448001534	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1087448001535	active site turn [active]
1087448001536	phosphorylation site [posttranslational modification]
1087448001537	Putative cell-wall binding lipoprotein; Region: YkyA; pfam10368
1087448001538	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1087448001539	Catalytic NodB homology domain of Streptococcus mutans polysaccharide deacetylase PgdA, Bacillus subtilis YheN, and similar proteins; Region: CE4_SmPgdA_like; cd10944
1087448001540	NodB motif; other site
1087448001541	active site
1087448001542	catalytic site [active]
1087448001543	Zn binding site [ion binding]; other site
1087448001544	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
1087448001545	Helix-turn-helix domain; Region: HTH_38; pfam13936
1087448001546	Integrase core domain; Region: rve; pfam00665
1087448001547	Nitroreductase-like family 1. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_1; cd02137
1087448001548	dimer interface [polypeptide binding]; other site
1087448001549	FMN binding site [chemical binding]; other site
1087448001550	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1087448001551	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1087448001552	active site
1087448001553	phosphorylation site [posttranslational modification]
1087448001554	intermolecular recognition site; other site
1087448001555	dimerization interface [polypeptide binding]; other site
1087448001556	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1087448001557	DNA binding site [nucleotide binding]
1087448001558	Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: STE14; COG2020
1087448001559	Bacterial SH3 domain; Region: SH3_3; pfam08239
1087448001560	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: VanY; COG1876
1087448001561	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
1087448001562	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1087448001563	Predicted membrane protein, putative toxin regulator [General function prediction only]; Region: PfoR; COG3641
1087448001564	Phosphotransferase system, EIIC; Region: PTS_EIIC_2; pfam13303
1087448001565	Calcineurin-like phosphoesterase superfamily domain; Region: Metallophos_2; pfam12850
1087448001566	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1087448001567	active site
1087448001568	metal binding site [ion binding]; metal-binding site
1087448001569	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1087448001570	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1087448001571	Predicted membrane protein [Function unknown]; Region: COG1511
1087448001572	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
1087448001573	X-X-X-Leu-X-X-Gly heptad repeats; Region: xxxLxxG_by_4; TIGR03057
1087448001574	YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062
1087448001575	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1087448001576	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
1087448001577	NADP binding site [chemical binding]; other site
1087448001578	dimer interface [polypeptide binding]; other site
1087448001579	Haemolytic domain; Region: Haemolytic; pfam01809
1087448001580	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235
1087448001581	NADP+-dependent p-hydroxybenzaldehyde dehydrogenase-like; Region: ALDH_HBenzADH; cd07151
1087448001582	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1087448001583	NAD(P) binding site [chemical binding]; other site
1087448001584	catalytic residues [active]
1087448001585	Predicted membrane protein (DUF2254); Region: DUF2254; pfam10011
1087448001586	Predicted membrane protein [Function unknown]; Region: COG4325
1087448001587	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2839
1087448001588	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1087448001589	Domain of unknown function DUF21; Region: DUF21; pfam01595
1087448001590	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1087448001591	Transporter associated domain; Region: CorC_HlyC; smart01091
1087448001592	peroxiredoxin, Ohr subfamily; Region: organ_hyd_perox; TIGR03561
1087448001593	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
1087448001594	conserved cys residue [active]
1087448001595	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1087448001596	Methylmalonyl-CoA epimerase (MMCE); Region: MMCE; cd07249
1087448001597	dimer interface [polypeptide binding]; other site
1087448001598	substrate binding site [chemical binding]; other site
1087448001599	metal binding site [ion binding]; metal-binding site
1087448001600	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
1087448001601	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1087448001602	Peptidase family M23; Region: Peptidase_M23; pfam01551
1087448001603	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
1087448001604	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1087448001605	Peptidase family M23; Region: Peptidase_M23; pfam01551
1087448001606	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1087448001607	dimer interface [polypeptide binding]; other site
1087448001608	substrate binding site [chemical binding]; other site
1087448001609	ATP binding site [chemical binding]; other site
1087448001610	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
1087448001611	substrate binding site [chemical binding]; other site
1087448001612	multimerization interface [polypeptide binding]; other site
1087448001613	ATP binding site [chemical binding]; other site
1087448001614	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1087448001615	thiamine phosphate binding site [chemical binding]; other site
1087448001616	active site
1087448001617	pyrophosphate binding site [ion binding]; other site
1087448001618	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1087448001619	dimerization interface [polypeptide binding]; other site
1087448001620	putative DNA binding site [nucleotide binding]; other site
1087448001621	putative Zn2+ binding site [ion binding]; other site
1087448001622	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1087448001623	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1087448001624	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1087448001625	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1087448001626	Formate/nitrite transporter; Region: Form_Nir_trans; pfam01226
1087448001627	Protein of unknown function (DUF1232); Region: DUF1232; pfam06803
1087448001628	Thermophilic metalloprotease (M29); Region: Peptidase_M29; pfam02073
1087448001629	Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309
1087448001630	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
1087448001631	FAD binding domain; Region: FAD_binding_4; pfam01565
1087448001632	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1087448001633	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1087448001634	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1087448001635	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1087448001636	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1087448001637	Coenzyme A binding pocket [chemical binding]; other site
1087448001638	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1087448001639	Coenzyme A binding pocket [chemical binding]; other site
1087448001640	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
1087448001641	dimer interface [polypeptide binding]; other site
1087448001642	FMN binding site [chemical binding]; other site
1087448001643	NADPH bind site [chemical binding]; other site
1087448001644	Transcriptional regulator [Transcription]; Region: LytR; COG1316
1087448001645	atypical (a) SDRs, subgroup 5; Region: SDR_a5; cd05243
1087448001646	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1087448001647	NAD(P) binding site [chemical binding]; other site
1087448001648	putative active site [active]
1087448001649	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1087448001650	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1087448001651	catalytic residues [active]
1087448001652	Na+/H+ antiporter family; Region: Na_H_antiporter; pfam03553
1087448001653	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
1087448001654	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1087448001655	Ornithine acetyltransferase (OAT) family; also referred to as ArgJ. OAT catalyzes the first and fifth steps in arginine biosynthesis, coupling acetylation of glutamate with deacetylation of N-acetylornithine, which allows recycling of the acetyl group in...; Region: OAT; cd02152
1087448001656	heterotetramer interface [polypeptide binding]; other site
1087448001657	active site pocket [active]
1087448001658	cleavage site
1087448001659	AAK_NAGK-like: N-Acetyl-L-glutamate kinase (NAGK)-like . Included in this CD are the Escherichia coli and Pseudomonas aeruginosa type NAGKs which catalyze the phosphorylation of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine...; Region: AAK_NAGK-like; cd04238
1087448001660	nucleotide binding site [chemical binding]; other site
1087448001661	N-acetyl-L-glutamate binding site [chemical binding]; other site
1087448001662	acetylornithine aminotransferase; Provisional; Region: argD; PRK02936
1087448001663	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1087448001664	inhibitor-cofactor binding pocket; inhibition site
1087448001665	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1087448001666	catalytic residue [active]
1087448001667	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12838
1087448001668	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; pfam00988
1087448001669	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1087448001670	catalytic site [active]
1087448001671	subunit interface [polypeptide binding]; other site
1087448001672	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1087448001673	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
1087448001674	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1087448001675	Lipase.  Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883
1087448001676	formate--tetrahydrofolate ligase; Provisional; Region: PRK13505
1087448001677	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
1087448001678	Potassium binding sites [ion binding]; other site
1087448001679	Cesium cation binding sites [ion binding]; other site
1087448001680	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1087448001681	dimer interface [polypeptide binding]; other site
1087448001682	conserved gate region; other site
1087448001683	putative PBP binding loops; other site
1087448001684	ABC-ATPase subunit interface; other site
1087448001685	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1087448001686	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1087448001687	dimer interface [polypeptide binding]; other site
1087448001688	conserved gate region; other site
1087448001689	putative PBP binding loops; other site
1087448001690	ABC-ATPase subunit interface; other site
1087448001691	asparagine synthetase AsnA; Provisional; Region: PRK05425
1087448001692	motif 1; other site
1087448001693	dimer interface [polypeptide binding]; other site
1087448001694	active site
1087448001695	motif 2; other site
1087448001696	motif 3; other site
1087448001697	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1087448001698	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1087448001699	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
1087448001700	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1087448001701	TrkA-C domain; Region: TrkA_C; pfam02080
1087448001702	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1087448001703	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1087448001704	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1087448001705	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
1087448001706	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1087448001707	dimerization interface [polypeptide binding]; other site
1087448001708	Histidine kinase; Region: His_kinase; pfam06580
1087448001709	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
1087448001710	ATP binding site [chemical binding]; other site
1087448001711	G-X-G motif; other site
1087448001712	Response regulator receiver domain; Region: Response_reg; pfam00072
1087448001713	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1087448001714	active site
1087448001715	phosphorylation site [posttranslational modification]
1087448001716	intermolecular recognition site; other site
1087448001717	dimerization interface [polypeptide binding]; other site
1087448001718	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1087448001719	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1087448001720	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
1087448001721	Uridine phosphorylase [Nucleotide transport and metabolism]; Region: Udp; COG2820
1087448001722	Bacillus subtilis aldehyde dehydrogenase ywdH-like; Region: ALDH_YwdH-P39616; cd07136
1087448001723	aldehyde dehydrogenase family protein; Provisional; Region: PTZ00381
1087448001724	NAD(P) binding site [chemical binding]; other site
1087448001725	catalytic residues [active]
1087448001726	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
1087448001727	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Region: Glyphos_transf; pfam04464
1087448001728	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1087448001729	Cytidylyltransferase; Region: CTP_transf_2; pfam01467
1087448001730	active site
1087448001731	nucleotide binding site [chemical binding]; other site
1087448001732	HIGH motif; other site
1087448001733	KMSKS motif; other site
1087448001734	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
1087448001735	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Region: Glyphos_transf; pfam04464
1087448001736	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1087448001737	CRP/FNR family transcriptional regulator; Provisional; Region: PRK13918
1087448001738	ligand binding site [chemical binding]; other site
1087448001739	flexible hinge region; other site
1087448001740	Heme/copper-type cytochrome/quinol oxidases, subunit 2 [Energy production and conversion]; Region: CyoA; COG1622
1087448001741	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
1087448001742	ba3-like heme-copper oxidase subunit I.  The ba3 family of heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and some archaea which catalyze the reduction of O2 and simultaneously pump protons across the...; Region: ba3-like_Oxidase_I; cd01660
1087448001743	Putative D-pathway homolog; other site
1087448001744	Cytochrome C and Quinol oxidase polypeptide I; Region: COX1; pfam00115
1087448001745	Low-spin heme binding site [chemical binding]; other site
1087448001746	Subunit I/II interface [polypeptide binding]; other site
1087448001747	Putative Q-pathway; other site
1087448001748	Putative alternate electron transfer pathway; other site
1087448001749	Putative water exit pathway; other site
1087448001750	Binuclear center (active site) [active]
1087448001751	Putative K-pathway homolog; other site
1087448001752	Putative proton exit pathway; other site
1087448001753	Subunit I/IIa interface [polypeptide binding]; other site
1087448001754	Electron transfer pathway; other site
1087448001755	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1087448001756	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1087448001757	active site
1087448001758	phosphorylation site [posttranslational modification]
1087448001759	intermolecular recognition site; other site
1087448001760	dimerization interface [polypeptide binding]; other site
1087448001761	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1087448001762	DNA binding residues [nucleotide binding]
1087448001763	dimerization interface [polypeptide binding]; other site
1087448001764	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
1087448001765	The ML (MD-2-related lipid-recognition) domain is present in MD-1, MD-2, GM2 activator protein, Niemann-Pick type C2 (Npc2) protein, phosphatidylinositol/phosphatidylglycerol transfer protein (PG/PI-TP), mite allergen Der p 2  and several proteins of...; Region: ML; cl00274
1087448001766	putative lipid binding cavity [chemical binding]; other site
1087448001767	Histidine kinase; Region: HisKA_3; pfam07730
1087448001768	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1087448001769	ATP binding site [chemical binding]; other site
1087448001770	Mg2+ binding site [ion binding]; other site
1087448001771	G-X-G motif; other site
1087448001772	Predicted membrane protein [Function unknown]; Region: COG4758
1087448001773	Cell wall-active antibiotics response protein (DUF2154); Region: DUF2154; pfam09922
1087448001774	Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842
1087448001775	GTPase RsgA; Reviewed; Region: PRK01889
1087448001776	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1087448001777	RNA binding site [nucleotide binding]; other site
1087448001778	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
1087448001779	GTPase/Zn-binding domain interface [polypeptide binding]; other site
1087448001780	GTP/Mg2+ binding site [chemical binding]; other site
1087448001781	G4 box; other site
1087448001782	G5 box; other site
1087448001783	G1 box; other site
1087448001784	Switch I region; other site
1087448001785	G2 box; other site
1087448001786	G3 box; other site
1087448001787	Switch II region; other site
1087448001788	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1087448001789	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1087448001790	Walker A/P-loop; other site
1087448001791	ATP binding site [chemical binding]; other site
1087448001792	Q-loop/lid; other site
1087448001793	ABC transporter signature motif; other site
1087448001794	Walker B; other site
1087448001795	H-loop/switch region; other site
1087448001796	ABC transporter; Region: ABC_tran_2; pfam12848
1087448001797	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1087448001798	pyruvate formate-lyase 1-activating enzyme; Region: PFLA; TIGR02493
1087448001799	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1087448001800	FeS/SAM binding site; other site
1087448001801	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
1087448001802	Pyruvate formate lyase 1; Region: PFL1; cd01678
1087448001803	coenzyme A binding site [chemical binding]; other site
1087448001804	active site
1087448001805	catalytic residues [active]
1087448001806	glycine loop; other site
1087448001807	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
1087448001808	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1087448001809	ATP binding site [chemical binding]; other site
1087448001810	putative Mg++ binding site [ion binding]; other site
1087448001811	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1087448001812	nucleotide binding region [chemical binding]; other site
1087448001813	ATP-binding site [chemical binding]; other site
1087448001814	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1087448001815	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1087448001816	metal binding site [ion binding]; metal-binding site
1087448001817	active site
1087448001818	I-site; other site
1087448001819	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1087448001820	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1087448001821	Walker A/P-loop; other site
1087448001822	ATP binding site [chemical binding]; other site
1087448001823	ABC transporter signature motif; other site
1087448001824	Walker B; other site
1087448001825	D-loop; other site
1087448001826	H-loop/switch region; other site
1087448001827	ABC transporter; Region: ABC_tran_2; pfam12848
1087448001828	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1087448001829	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1087448001830	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1087448001831	putative acyl-acceptor binding pocket; other site
1087448001832	Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only]; Region: COG2996
1087448001833	S1 domain; Region: S1_2; pfam13509
1087448001834	helicase 45; Provisional; Region: PTZ00424
1087448001835	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1087448001836	ATP binding site [chemical binding]; other site
1087448001837	Mg++ binding site [ion binding]; other site
1087448001838	motif III; other site
1087448001839	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1087448001840	nucleotide binding region [chemical binding]; other site
1087448001841	ATP-binding site [chemical binding]; other site
1087448001842	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1087448001843	EAL-domain associated signalling protein domain; Region: YkuI_C; pfam10388
1087448001844	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1087448001845	active site
1087448001846	HTH-like domain; Region: HTH_21; pfam13276
1087448001847	Integrase core domain; Region: rve; pfam00665
1087448001848	Integrase core domain; Region: rve_3; cl15866
1087448001849	Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion; Region: enolase_like; cl17188
1087448001850	o-succinylbenzoate synthase; Region: menC_lowGC/arch; TIGR01928
1087448001851	metal binding site [ion binding]; metal-binding site
1087448001852	substrate binding pocket [chemical binding]; other site
1087448001853	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK03640
1087448001854	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
1087448001855	acyl-activating enzyme (AAE) consensus motif; other site
1087448001856	putative AMP binding site [chemical binding]; other site
1087448001857	putative active site [active]
1087448001858	putative CoA binding site [chemical binding]; other site
1087448001859	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1087448001860	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
1087448001861	substrate binding site [chemical binding]; other site
1087448001862	oxyanion hole (OAH) forming residues; other site
1087448001863	trimer interface [polypeptide binding]; other site
1087448001864	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Region: menH_SHCHC; TIGR03695
1087448001865	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1087448001866	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
1087448001867	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
1087448001868	dimer interface [polypeptide binding]; other site
1087448001869	tetramer interface [polypeptide binding]; other site
1087448001870	PYR/PP interface [polypeptide binding]; other site
1087448001871	TPP binding site [chemical binding]; other site
1087448001872	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
1087448001873	TPP-binding site; other site
1087448001874	salicylate biosynthesis isochorismate synthase; Validated; Region: PRK07054
1087448001875	chorismate binding enzyme; Region: Chorismate_bind; cl10555
1087448001876	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated; Region: PRK06080
1087448001877	UbiA prenyltransferase family; Region: UbiA; pfam01040
1087448001878	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1087448001879	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1087448001880	substrate binding site [chemical binding]; other site
1087448001881	ATP binding site [chemical binding]; other site
1087448001882	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
1087448001883	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1087448001884	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1087448001885	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1087448001886	motif II; other site
1087448001887	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1087448001888	EamA-like transporter family; Region: EamA; pfam00892
1087448001889	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1087448001890	putative substrate translocation pore; other site
1087448001891	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1087448001892	Radical SAM superfamily; Region: Radical_SAM; pfam04055
1087448001893	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1087448001894	FeS/SAM binding site; other site
1087448001895	YfkB-like domain; Region: YfkB; pfam08756
1087448001896	TRAM domain; Region: TRAM; pfam01938
1087448001897	23S rRNA (uracil-5-)-methyltransferase RumA; Region: rumA; TIGR00479
1087448001898	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1087448001899	S-adenosylmethionine binding site [chemical binding]; other site
1087448001900	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1087448001901	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1087448001902	active site
1087448001903	catalytic tetrad [active]
1087448001904	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1087448001905	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1087448001906	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1087448001907	active site
1087448001908	phosphorylation site [posttranslational modification]
1087448001909	intermolecular recognition site; other site
1087448001910	dimerization interface [polypeptide binding]; other site
1087448001911	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1087448001912	DNA binding site [nucleotide binding]
1087448001913	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1087448001914	Imidazolonepropionase and related amidohydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: HutI; COG1228
1087448001915	Metallo-dependent hydrolases, subgroup C is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_C; cd01309
1087448001916	active site
1087448001917	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
1087448001918	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
1087448001919	putative NAD(P) binding site [chemical binding]; other site
1087448001920	putative active site [active]
1087448001921	RecX family; Region: RecX; cl00936
1087448001922	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1087448001923	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
1087448001924	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1087448001925	Walker A/P-loop; other site
1087448001926	ATP binding site [chemical binding]; other site
1087448001927	Q-loop/lid; other site
1087448001928	ABC transporter signature motif; other site
1087448001929	Walker B; other site
1087448001930	D-loop; other site
1087448001931	H-loop/switch region; other site
1087448001932	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1087448001933	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1087448001934	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
1087448001935	Walker A/P-loop; other site
1087448001936	ATP binding site [chemical binding]; other site
1087448001937	Q-loop/lid; other site
1087448001938	ABC transporter signature motif; other site
1087448001939	Walker B; other site
1087448001940	D-loop; other site
1087448001941	H-loop/switch region; other site
1087448001942	Protein of unknown function (DUF1811); Region: DUF1811; pfam08838
1087448001943	WVELL protein; Region: WVELL; pfam14043
1087448001944	Predicted membrane-bound metal-dependent hydrolase (DUF457); Region: DUF457; pfam04307
1087448001945	A/G-specific adenine glycosylase; Region: mutY; TIGR01084
1087448001946	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1087448001947	minor groove reading motif; other site
1087448001948	helix-hairpin-helix signature motif; other site
1087448001949	substrate binding pocket [chemical binding]; other site
1087448001950	active site
1087448001951	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576
1087448001952	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
1087448001953	DNA binding and oxoG recognition site [nucleotide binding]
1087448001954	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
1087448001955	hydrophobic ligand binding site; other site
1087448001956	hypothetical protein; Provisional; Region: PRK13662
1087448001957	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1087448001958	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1087448001959	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1087448001960	Walker A/P-loop; other site
1087448001961	ATP binding site [chemical binding]; other site
1087448001962	Q-loop/lid; other site
1087448001963	ABC transporter signature motif; other site
1087448001964	Walker B; other site
1087448001965	D-loop; other site
1087448001966	H-loop/switch region; other site
1087448001967	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK12389
1087448001968	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1087448001969	inhibitor-cofactor binding pocket; inhibition site
1087448001970	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1087448001971	catalytic residue [active]
1087448001972	ferric uptake regulator; Provisional; Region: fur; PRK09462
1087448001973	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1087448001974	metal binding site 2 [ion binding]; metal-binding site
1087448001975	putative DNA binding helix; other site
1087448001976	metal binding site 1 [ion binding]; metal-binding site
1087448001977	dimer interface [polypeptide binding]; other site
1087448001978	structural Zn2+ binding site [ion binding]; other site
1087448001979	Protein of unknown function (DUF2614); Region: DUF2614; pfam11023
1087448001980	epoxyqueuosine reductase; Region: TIGR00276
1087448001981	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
1087448001982	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1087448001983	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1087448001984	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1087448001985	DNA binding site [nucleotide binding]
1087448001986	active site
1087448001987	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
1087448001988	sensory histidine kinase DcuS; Provisional; Region: PRK11086
1087448001989	Transglycosylase; Region: Transgly; pfam00912
1087448001990	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
1087448001991	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1087448001992	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK05293
1087448001993	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
1087448001994	ligand binding site; other site
1087448001995	oligomer interface; other site
1087448001996	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
1087448001997	dimer interface [polypeptide binding]; other site
1087448001998	N-terminal domain interface [polypeptide binding]; other site
1087448001999	sulfate 1 binding site; other site
1087448002000	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1087448002001	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
1087448002002	dimer interface [polypeptide binding]; other site
1087448002003	N-terminal domain interface [polypeptide binding]; other site
1087448002004	sulfate 1 binding site; other site
1087448002005	glycogen synthase; Provisional; Region: glgA; PRK00654
1087448002006	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
1087448002007	ADP-binding pocket [chemical binding]; other site
1087448002008	homodimer interface [polypeptide binding]; other site
1087448002009	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1087448002010	glycogen/starch/alpha-glucan phosphorylases; Region: P_ylase; TIGR02093
1087448002011	active site pocket [active]
1087448002012	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
1087448002013	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
1087448002014	active site residue [active]
1087448002015	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
1087448002016	active site residue [active]
1087448002017	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
1087448002018	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
1087448002019	active site
1087448002020	substrate binding site [chemical binding]; other site
1087448002021	metal binding site [ion binding]; metal-binding site
1087448002022	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1087448002023	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1087448002024	active site
1087448002025	catalytic tetrad [active]
1087448002026	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1087448002027	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1087448002028	dimer interface [polypeptide binding]; other site
1087448002029	conserved gate region; other site
1087448002030	putative PBP binding loops; other site
1087448002031	ABC-ATPase subunit interface; other site
1087448002032	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1087448002033	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1087448002034	substrate binding pocket [chemical binding]; other site
1087448002035	membrane-bound complex binding site; other site
1087448002036	hinge residues; other site
1087448002037	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1087448002038	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1087448002039	Walker A/P-loop; other site
1087448002040	ATP binding site [chemical binding]; other site
1087448002041	Q-loop/lid; other site
1087448002042	ABC transporter signature motif; other site
1087448002043	Walker B; other site
1087448002044	D-loop; other site
1087448002045	H-loop/switch region; other site
1087448002046	Transthyretin_like.  This domain is present in the transthyretin-like protein (TLP) family which includes transthyretin (TTR) and a transthyretin-related protein called 5-hydroxyisourate hydrolase (HIUase).  TTR and HIUase are homotetrameric proteins...; Region: Transthyretin_like; cl17222
1087448002047	active site
1087448002048	homotetramer interface [polypeptide binding]; other site
1087448002049	TOBE domain; Region: TOBE; pfam03459
1087448002050	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1087448002051	Protein of unknown function (DUF445); Region: DUF445; pfam04286
1087448002052	hypothetical protein; Provisional; Region: PRK13676
1087448002053	YhzD-like protein; Region: YhzD; pfam14120
1087448002054	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
1087448002055	active site
1087448002056	DNA polymerase IV; Validated; Region: PRK02406
1087448002057	DNA binding site [nucleotide binding]
1087448002058	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
1087448002059	Escherichia coli CorA-Salmonella typhimurium ZntB_like family; Region: EcCorA_ZntB-like; cd12821
1087448002060	Cl binding site [ion binding]; other site
1087448002061	oligomer interface [polypeptide binding]; other site
1087448002062	3'-5' exoribonuclease YhaM; Provisional; Region: PRK13480
1087448002063	YhaM_OBF_like: A subfamily of OB folds similar to that found in Bacillus subtilis YhaM and Staphylococcus aureus cmp-binding factor-1 (SaCBF1). Both these proteins are 3'-to-5'exoribonucleases. YhaM requires Mn2+ or Co2+ for activity and is...; Region: YhaM_OBF_like; cd04492
1087448002064	generic binding surface II; other site
1087448002065	generic binding surface I; other site
1087448002066	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1087448002067	Zn2+ binding site [ion binding]; other site
1087448002068	Mg2+ binding site [ion binding]; other site
1087448002069	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1087448002070	Old yellow enzyme (OYE) YqjM-like FMN binding domain. YqjM is involved in the oxidative stress response of Bacillus subtilis.  Like the other OYE members, each monomer of YqjM contains FMN as a non-covalently bound cofactor and uses NADPH as a reducing...; Region: OYE_YqiM_FMN; cd02932
1087448002071	active site
1087448002072	FMN binding site [chemical binding]; other site
1087448002073	substrate binding site [chemical binding]; other site
1087448002074	homotetramer interface [polypeptide binding]; other site
1087448002075	catalytic residue [active]
1087448002076	peptidylprolyl isomerase; Reviewed; Region: prsA; PRK03002
1087448002077	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1087448002078	transcriptional regulator Hpr; Provisional; Region: PRK13777
1087448002079	MarR family; Region: MarR; pfam01047
1087448002080	Predicted membrane protein [Function unknown]; Region: COG2261
1087448002081	Predicted membrane protein [Function unknown]; Region: COG2261
1087448002082	Predicted membrane protein [Function unknown]; Region: COG2261
1087448002083	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1087448002084	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1087448002085	Walker A/P-loop; other site
1087448002086	ATP binding site [chemical binding]; other site
1087448002087	Q-loop/lid; other site
1087448002088	ABC transporter signature motif; other site
1087448002089	Walker B; other site
1087448002090	D-loop; other site
1087448002091	H-loop/switch region; other site
1087448002092	Bacterial ABC transporter protein EcsB; Region: EcsB; pfam05975
1087448002093	Ammonia permease [Inorganic ion transport and metabolism]; Region: AmtB; COG0004
1087448002094	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
1087448002095	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1087448002096	DNA binding residues [nucleotide binding]
1087448002097	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
1087448002098	substrate binding site [chemical binding]; other site
1087448002099	active site
1087448002100	ferrochelatase; Provisional; Region: PRK12435
1087448002101	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1087448002102	C-terminal domain interface [polypeptide binding]; other site
1087448002103	active site
1087448002104	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1087448002105	active site
1087448002106	N-terminal domain interface [polypeptide binding]; other site
1087448002107	cardiolipin synthase; Region: bac_cardiolipin; TIGR04265
1087448002108	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
1087448002109	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
1087448002110	putative active site [active]
1087448002111	catalytic site [active]
1087448002112	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
1087448002113	putative active site [active]
1087448002114	catalytic site [active]
1087448002115	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1087448002116	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1087448002117	active site
1087448002118	motif I; other site
1087448002119	motif II; other site
1087448002120	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1087448002121	Large-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscL; COG1970
1087448002122	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
1087448002123	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
1087448002124	Part of AAA domain; Region: AAA_19; pfam13245
1087448002125	Family description; Region: UvrD_C_2; pfam13538
1087448002126	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1087448002127	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1087448002128	Coenzyme A binding pocket [chemical binding]; other site
1087448002129	sucrose-6-phosphate hydrolase; Region: scrB_fam; TIGR01322
1087448002130	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
1087448002131	substrate binding [chemical binding]; other site
1087448002132	active site
1087448002133	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
1087448002134	HAMP domain; Region: HAMP; pfam00672
1087448002135	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1087448002136	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1087448002137	metal binding site [ion binding]; metal-binding site
1087448002138	active site
1087448002139	I-site; other site
1087448002140	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1087448002141	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1087448002142	Walker A/P-loop; other site
1087448002143	ATP binding site [chemical binding]; other site
1087448002144	Q-loop/lid; other site
1087448002145	ABC transporter signature motif; other site
1087448002146	Walker B; other site
1087448002147	D-loop; other site
1087448002148	H-loop/switch region; other site
1087448002149	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
1087448002150	Predicted membrane protein [Function unknown]; Region: COG2364
1087448002151	Glycerol-3-phosphate responsive antiterminator; Region: G3P_antiterm; cl00852
1087448002152	Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism]; Region: GlpF; COG0580
1087448002153	amphipathic channel; other site
1087448002154	Asn-Pro-Ala signature motifs; other site
1087448002155	glycerol kinase; Provisional; Region: glpK; PRK00047
1087448002156	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
1087448002157	N- and C-terminal domain interface [polypeptide binding]; other site
1087448002158	active site
1087448002159	MgATP binding site [chemical binding]; other site
1087448002160	catalytic site [active]
1087448002161	metal binding site [ion binding]; metal-binding site
1087448002162	glycerol binding site [chemical binding]; other site
1087448002163	homotetramer interface [polypeptide binding]; other site
1087448002164	homodimer interface [polypeptide binding]; other site
1087448002165	FBP binding site [chemical binding]; other site
1087448002166	protein IIAGlc interface [polypeptide binding]; other site
1087448002167	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578
1087448002168	Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FrnE; COG2761
1087448002169	DsbA family, FrnE subfamily; FrnE is a DsbA-like protein containing a CXXC motif. It is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the aromatic antibiotics frenolicin and nanaomycins; Region: DsbA_FrnE; cd03024
1087448002170	catalytic residues [active]
1087448002171	lipoyltransferase and lipoate-protein ligase; Region: lipoyltrans; TIGR00545
1087448002172	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
1087448002173	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
1087448002174	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
1087448002175	short chain dehydrogenase; Provisional; Region: PRK06701
1087448002176	NAD binding site [chemical binding]; other site
1087448002177	metal binding site [ion binding]; metal-binding site
1087448002178	active site
1087448002179	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK07656
1087448002180	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
1087448002181	acyl-activating enzyme (AAE) consensus motif; other site
1087448002182	putative AMP binding site [chemical binding]; other site
1087448002183	putative active site [active]
1087448002184	putative CoA binding site [chemical binding]; other site
1087448002185	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
1087448002186	active site
1087448002187	dimer interfaces [polypeptide binding]; other site
1087448002188	catalytic residues [active]
1087448002189	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1087448002190	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1087448002191	active site
1087448002192	phosphorylation site [posttranslational modification]
1087448002193	intermolecular recognition site; other site
1087448002194	dimerization interface [polypeptide binding]; other site
1087448002195	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1087448002196	DNA binding site [nucleotide binding]
1087448002197	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
1087448002198	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1087448002199	dimerization interface [polypeptide binding]; other site
1087448002200	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1087448002201	dimer interface [polypeptide binding]; other site
1087448002202	phosphorylation site [posttranslational modification]
1087448002203	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1087448002204	ATP binding site [chemical binding]; other site
1087448002205	Mg2+ binding site [ion binding]; other site
1087448002206	G-X-G motif; other site
1087448002207	ComK protein; Region: ComK; cl11560
1087448002208	Truncated hemoglobins (trHbs) are a family of oxygen-binding heme proteins found in cyanobacteria, eubacteria, unicellular eukaryotes, and plants. The truncated hemoglobins have a characteristic two-over-two alpha helical folding pattern that is distinct...; Region: Trunc_globin; cd00454
1087448002209	apolar tunnel; other site
1087448002210	heme binding site [chemical binding]; other site
1087448002211	dimerization interface [polypeptide binding]; other site
1087448002212	helicase-exonuclease AddAB, AddB subunit; Region: addB_Gpos; TIGR02773
1087448002213	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1087448002214	helicase-exonuclease AddAB, AddA subunit, Firmicutes type; Region: addA_Gpos; TIGR02785
1087448002215	Part of AAA domain; Region: AAA_19; pfam13245
1087448002216	Family description; Region: UvrD_C_2; pfam13538
1087448002217	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1087448002218	Response regulator receiver domain; Region: Response_reg; pfam00072
1087448002219	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1087448002220	active site
1087448002221	phosphorylation site [posttranslational modification]
1087448002222	intermolecular recognition site; other site
1087448002223	dimerization interface [polypeptide binding]; other site
1087448002224	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1087448002225	dimerization interface [polypeptide binding]; other site
1087448002226	GAF domain; Region: GAF_3; pfam13492
1087448002227	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
1087448002228	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1087448002229	dimer interface [polypeptide binding]; other site
1087448002230	phosphorylation site [posttranslational modification]
1087448002231	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1087448002232	ATP binding site [chemical binding]; other site
1087448002233	G-X-G motif; other site
1087448002234	Protein of unknown function (DUF1516); Region: DUF1516; cl11654
1087448002235	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1087448002236	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1087448002237	S-adenosylmethionine binding site [chemical binding]; other site
1087448002238	phytoene desaturase; Region: crtI_fam; TIGR02734
1087448002239	phytoene desaturase; Region: crtI_fam; TIGR02734
1087448002240	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1087448002241	Trans-Isoprenyl Diphosphate Synthases, head-to-head; Region: Trans_IPPS_HH; cd00683
1087448002242	catalytic residues [active]
1087448002243	substrate binding pocket [chemical binding]; other site
1087448002244	substrate-Mg2+ binding site; other site
1087448002245	aspartate-rich region 1; other site
1087448002246	aspartate-rich region 2; other site
1087448002247	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1087448002248	phytoene desaturase; Region: crtI_fam; TIGR02734
1087448002249	hopene-associated glycosyltransferase HpnB; Region: HpnB; TIGR03469
1087448002250	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1087448002251	active site
1087448002252	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1087448002253	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cd06551
1087448002254	putative acyl-acceptor binding pocket; other site
1087448002255	Protein of unknown function (DUF422); Region: DUF422; cl00991
1087448002256	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
1087448002257	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
1087448002258	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
1087448002259	putative deacylase active site [active]
1087448002260	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_8; cd13134
1087448002261	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1087448002262	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1087448002263	enoyl-CoA hydratase; Provisional; Region: PRK08140
1087448002264	substrate binding site [chemical binding]; other site
1087448002265	oxyanion hole (OAH) forming residues; other site
1087448002266	trimer interface [polypeptide binding]; other site
1087448002267	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
1087448002268	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
1087448002269	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
1087448002270	homodimer interface [polypeptide binding]; other site
1087448002271	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
1087448002272	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
1087448002273	active site
1087448002274	homodimer interface [polypeptide binding]; other site
1087448002275	catalytic site [active]
1087448002276	Beta-galactosidase C-terminal domain; Region: Glyco_hydro_42C; pfam08533
1087448002277	Maltose-binding periplasmic proteins/domains [Carbohydrate transport and metabolism]; Region: MalE; COG2182
1087448002278	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1087448002279	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1087448002280	dimer interface [polypeptide binding]; other site
1087448002281	conserved gate region; other site
1087448002282	ABC-ATPase subunit interface; other site
1087448002283	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1087448002284	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1087448002285	dimer interface [polypeptide binding]; other site
1087448002286	conserved gate region; other site
1087448002287	putative PBP binding loops; other site
1087448002288	ABC-ATPase subunit interface; other site
1087448002289	Alpha amylase catalytic domain found in bacterial cyclomaltodextrinases and related proteins; Region: AmyAc_bac_CMD_like_2; cd11339
1087448002290	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
1087448002291	active site
1087448002292	catalytic site [active]
1087448002293	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1087448002294	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1087448002295	DNA binding site [nucleotide binding]
1087448002296	domain linker motif; other site
1087448002297	Ligand-binding domain of uncharacterized transcription regulator ycjW which is a member of the LacI-GalR family repressors; Region: PBP1_ycjW_transcription_regulator_like; cd06294
1087448002298	putative dimerization interface [polypeptide binding]; other site
1087448002299	putative ligand binding site [chemical binding]; other site
1087448002300	maltose phosphorylase; Provisional; Region: PRK13807
1087448002301	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
1087448002302	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
1087448002303	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
1087448002304	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1087448002305	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1087448002306	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1087448002307	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1087448002308	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1087448002309	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1087448002310	active site
1087448002311	motif I; other site
1087448002312	motif II; other site
1087448002313	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
1087448002314	Protein of unknown function (DUF2929); Region: DUF2929; pfam11151
1087448002315	isoaspartyl dipeptidase; Provisional; Region: PRK10657
1087448002316	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1087448002317	active site
1087448002318	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1087448002319	catalytic residues [active]
1087448002320	phosphatidylserine decarboxylase; Provisional; Region: PRK03140
1087448002321	Predicted hydrolase of the HAD superfamily [General function prediction only]; Region: COG2179
1087448002322	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1087448002323	motif II; other site
1087448002324	GTPase YqeH; Provisional; Region: PRK13796
1087448002325	Circularly permuted YqeH GTPase; Region: YqeH; cd01855
1087448002326	GTP/Mg2+ binding site [chemical binding]; other site
1087448002327	G4 box; other site
1087448002328	G5 box; other site
1087448002329	G1 box; other site
1087448002330	Switch I region; other site
1087448002331	G2 box; other site
1087448002332	G3 box; other site
1087448002333	Switch II region; other site
1087448002334	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
1087448002335	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1087448002336	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1087448002337	shikimate binding site; other site
1087448002338	NAD(P) binding site [chemical binding]; other site
1087448002339	Predicted RNA-binding protein containing KH domain, possibly ribosomal protein [Translation, ribosomal structure and biogenesis]; Region: COG1534
1087448002340	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
1087448002341	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1087448002342	active site
1087448002343	(T/H)XGH motif; other site
1087448002344	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1087448002345	Zn2+ binding site [ion binding]; other site
1087448002346	Mg2+ binding site [ion binding]; other site
1087448002347	iojap-like ribosome-associated protein; Region: iojap_ybeB; TIGR00090
1087448002348	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1087448002349	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1087448002350	S-adenosylmethionine binding site [chemical binding]; other site
1087448002351	SLBB domain; Region: SLBB; pfam10531
1087448002352	comEA protein; Region: comE; TIGR01259
1087448002353	Helix-hairpin-helix motif; Region: HHH; pfam00633
1087448002354	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
1087448002355	DNA internalization-related competence protein ComEC/Rec2; Region: ComEC_Rec2; TIGR00361
1087448002356	Competence protein; Region: Competence; pfam03772
1087448002357	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1087448002358	YqzM-like protein; Region: YqzM; pfam14141
1087448002359	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
1087448002360	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1087448002361	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1087448002362	Coenzyme A binding pocket [chemical binding]; other site
1087448002363	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1087448002364	GTP-binding protein LepA; Provisional; Region: PRK05433
1087448002365	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1087448002366	G1 box; other site
1087448002367	putative GEF interaction site [polypeptide binding]; other site
1087448002368	GTP/Mg2+ binding site [chemical binding]; other site
1087448002369	Switch I region; other site
1087448002370	G2 box; other site
1087448002371	G3 box; other site
1087448002372	Switch II region; other site
1087448002373	G4 box; other site
1087448002374	G5 box; other site
1087448002375	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1087448002376	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1087448002377	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1087448002378	coproporphyrinogen III oxidase; Provisional; Region: PRK08599
1087448002379	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1087448002380	FeS/SAM binding site; other site
1087448002381	HemN C-terminal domain; Region: HemN_C; pfam06969
1087448002382	heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082
1087448002383	Winged helix-turn-helix transcription repressor, HrcA DNA-binding; Region: HrcA_DNA-bdg; pfam03444
1087448002384	heat shock protein GrpE; Provisional; Region: PRK14140
1087448002385	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1087448002386	dimer interface [polypeptide binding]; other site
1087448002387	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1087448002388	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1087448002389	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
1087448002390	nucleotide binding site [chemical binding]; other site
1087448002391	NEF interaction site [polypeptide binding]; other site
1087448002392	SBD interface [polypeptide binding]; other site
1087448002393	chaperone protein DnaJ; Provisional; Region: PRK14280
1087448002394	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1087448002395	HSP70 interaction site [polypeptide binding]; other site
1087448002396	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1087448002397	Zn binding sites [ion binding]; other site
1087448002398	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1087448002399	dimer interface [polypeptide binding]; other site
1087448002400	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
1087448002401	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1087448002402	S-adenosylmethionine binding site [chemical binding]; other site
1087448002403	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
1087448002404	RNA methyltransferase, RsmE family; Region: TIGR00046
1087448002405	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
1087448002406	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1087448002407	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1087448002408	FeS/SAM binding site; other site
1087448002409	TRAM domain; Region: TRAM; cl01282
1087448002410	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1087448002411	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1087448002412	RNA binding surface [nucleotide binding]; other site
1087448002413	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
1087448002414	probable active site [active]
1087448002415	Predicted permeases [General function prediction only]; Region: RarD; COG2962
1087448002416	Predicted permeases [General function prediction only]; Region: RarD; COG2962
1087448002417	Multidrug resistance efflux transporter; Region: EmrE; pfam13536
1087448002418	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
1087448002419	intersubunit interface [polypeptide binding]; other site
1087448002420	active site
1087448002421	catalytic residue [active]
1087448002422	Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only]; Region: Med; COG1744
1087448002423	Periplasmic binding component of a family of basic membrane lipoproteins from Borrelia and various putative lipoproteins from other bacteria; Region: PBP1_BmpA_like; cd06304
1087448002424	ligand binding site [chemical binding]; other site
1087448002425	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1087448002426	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1087448002427	dimerization interface [polypeptide binding]; other site
1087448002428	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1087448002429	dimer interface [polypeptide binding]; other site
1087448002430	putative CheW interface [polypeptide binding]; other site
1087448002431	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
1087448002432	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1087448002433	Peptidase family M23; Region: Peptidase_M23; pfam01551
1087448002434	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
1087448002435	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1087448002436	NAD(P) binding site [chemical binding]; other site
1087448002437	active site
1087448002438	Protein of unknown function (DUF1232); Region: DUF1232; pfam06803
1087448002439	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1087448002440	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
1087448002441	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
1087448002442	motif II; other site
1087448002443	Predicted membrane protein, putative toxin regulator [General function prediction only]; Region: PfoR; COG3641
1087448002444	Phosphotransferase system, EIIC; Region: PTS_EIIC_2; pfam13303
1087448002445	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
1087448002446	Prostaglandin dehydrogenases; Region: PGDH; cd05288
1087448002447	NAD(P) binding site [chemical binding]; other site
1087448002448	substrate binding site [chemical binding]; other site
1087448002449	dimer interface [polypeptide binding]; other site
1087448002450	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4641
1087448002451	Glycosyl transferases group 1; Region: Glyco_trans_1_2; pfam13524
1087448002452	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1087448002453	active site
1087448002454	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1087448002455	S-adenosylmethionine binding site [chemical binding]; other site
1087448002456	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1087448002457	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
1087448002458	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1087448002459	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1087448002460	UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: WecC; COG0677
1087448002461	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1087448002462	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1087448002463	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; Region: UDPG_MGDP_dh_C; pfam03720
1087448002464	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
1087448002465	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1087448002466	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
1087448002467	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
1087448002468	Walker A/P-loop; other site
1087448002469	ATP binding site [chemical binding]; other site
1087448002470	Q-loop/lid; other site
1087448002471	ABC transporter signature motif; other site
1087448002472	Walker B; other site
1087448002473	D-loop; other site
1087448002474	H-loop/switch region; other site
1087448002475	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
1087448002476	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1087448002477	active site
1087448002478	homodimer interface [polypeptide binding]; other site
1087448002479	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
1087448002480	DHHW protein; Region: DHHW; pfam14286
1087448002481	Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; cl00581
1087448002482	Family 41 Carbohydrate-Binding Module from pullulanase-like enzymes; Region: CBM41_pullulanase; cd10315
1087448002483	carbohydrate binding site [chemical binding]; other site
1087448002484	Family 41 Carbohydrate-Binding Module from pullulanase-like enzymes; Region: CBM41_pullulanase; cd10315
1087448002485	carbohydrate binding site [chemical binding]; other site
1087448002486	pullulanase, type I; Region: pulA_typeI; TIGR02104
1087448002487	Early set domain associated with the catalytic domain of pullulanase (also called dextrinase and alpha-dextrin endo-1,6-alpha glucosidase); Region: E_set_Pullulanase; cd02860
1087448002488	Alpha amylase catalytic domain found in Pullulanase (also called dextrinase; alpha-dextrin endo-1,6-alpha glucosidase), limit dextrinase, and related proteins; Region: AmyAc_Pullulanase_LD-like; cd11341
1087448002489	Ca binding site [ion binding]; other site
1087448002490	active site
1087448002491	catalytic site [active]
1087448002492	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1087448002493	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
1087448002494	Yqey-like protein; Region: YqeY; pfam09424
1087448002495	NfeD-like C-terminal, partner-binding; Region: NfeD; cl00686
1087448002496	hypothetical protein; Provisional; Region: PRK13665
1087448002497	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1087448002498	PhoH-like protein; Region: PhoH; pfam02562
1087448002499	Predicted membrane-associated HD superfamily hydrolase [General function prediction only]; Region: COG1480
1087448002500	7TM receptor with intracellular HD hydrolase; Region: 7TM-7TMR_HD; pfam07698
1087448002501	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1087448002502	Zn2+ binding site [ion binding]; other site
1087448002503	Mg2+ binding site [ion binding]; other site
1087448002504	metal-binding heat shock protein; Provisional; Region: PRK00016
1087448002505	Prokaryotic diacylglycerol kinase; Region: DAGK_prokar; pfam01219
1087448002506	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1087448002507	active site
1087448002508	catalytic motif [active]
1087448002509	Zn binding site [ion binding]; other site
1087448002510	GTPase Era; Reviewed; Region: era; PRK00089
1087448002511	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1087448002512	G1 box; other site
1087448002513	GTP/Mg2+ binding site [chemical binding]; other site
1087448002514	Switch I region; other site
1087448002515	G2 box; other site
1087448002516	Switch II region; other site
1087448002517	G3 box; other site
1087448002518	G4 box; other site
1087448002519	G5 box; other site
1087448002520	KH domain; Region: KH_2; pfam07650
1087448002521	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
1087448002522	Recombination protein O N terminal; Region: RecO_N; pfam11967
1087448002523	Recombination protein O C terminal; Region: RecO_C; pfam02565
1087448002524	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
1087448002525	dimer interface [polypeptide binding]; other site
1087448002526	motif 1; other site
1087448002527	active site
1087448002528	motif 2; other site
1087448002529	motif 3; other site
1087448002530	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
1087448002531	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1087448002532	HTH domain; Region: HTH_11; pfam08279
1087448002533	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_4; cd04617
1087448002534	FOG: CBS domain [General function prediction only]; Region: COG0517
1087448002535	DNA primase; Validated; Region: dnaG; PRK05667
1087448002536	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1087448002537	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1087448002538	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1087448002539	active site
1087448002540	metal binding site [ion binding]; metal-binding site
1087448002541	interdomain interaction site; other site
1087448002542	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
1087448002543	RNA polymerase sigma factor RpoD; Validated; Region: PRK09210
1087448002544	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1087448002545	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1087448002546	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1087448002547	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1087448002548	DNA binding residues [nucleotide binding]
1087448002549	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
1087448002550	Predicted SAM-dependent methyltransferase [General function prediction only]; Region: COG2384
1087448002551	Family of unknown function (DUF633); Region: DUF633; pfam04816
1087448002552	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1087448002553	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
1087448002554	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3323
1087448002555	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
1087448002556	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1087448002557	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
1087448002558	4-Hydroxy-3-methylbut-2-enyl diphosphate reductase IspH [Lipid metabolism]; Region: lytB; COG0761
1087448002559	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1087448002560	HAMP domain; Region: HAMP; pfam00672
1087448002561	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1087448002562	dimer interface [polypeptide binding]; other site
1087448002563	phosphorylation site [posttranslational modification]
1087448002564	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1087448002565	ATP binding site [chemical binding]; other site
1087448002566	Mg2+ binding site [ion binding]; other site
1087448002567	G-X-G motif; other site
1087448002568	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
1087448002569	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1087448002570	ligand binding site [chemical binding]; other site
1087448002571	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
1087448002572	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1087448002573	ATP binding site [chemical binding]; other site
1087448002574	Mg++ binding site [ion binding]; other site
1087448002575	motif III; other site
1087448002576	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1087448002577	nucleotide binding region [chemical binding]; other site
1087448002578	ATP-binding site [chemical binding]; other site
1087448002579	endonuclease IV; Provisional; Region: PRK01060
1087448002580	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1087448002581	AP (apurinic/apyrimidinic) site pocket; other site
1087448002582	DNA interaction; other site
1087448002583	Metal-binding active site; metal-binding site
1087448002584	FeoA domain; Region: FeoA; pfam04023
1087448002585	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
1087448002586	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1087448002587	G1 box; other site
1087448002588	GTP/Mg2+ binding site [chemical binding]; other site
1087448002589	Switch I region; other site
1087448002590	G2 box; other site
1087448002591	G3 box; other site
1087448002592	Switch II region; other site
1087448002593	G4 box; other site
1087448002594	G5 box; other site
1087448002595	Nucleoside recognition; Region: Gate; pfam07670
1087448002596	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
1087448002597	Nucleoside recognition; Region: Gate; pfam07670
1087448002598	polyphosphate kinase; Provisional; Region: PRK05443
1087448002599	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
1087448002600	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
1087448002601	Catalytic C-terminal domain, first repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C1_like; cd09165
1087448002602	putative domain interface [polypeptide binding]; other site
1087448002603	putative active site [active]
1087448002604	catalytic site [active]
1087448002605	Catalytic C-terminal domain, second repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C2_like; cd09168
1087448002606	putative domain interface [polypeptide binding]; other site
1087448002607	putative active site [active]
1087448002608	catalytic site [active]
1087448002609	exopolyphosphatase; Region: exo_poly_only; TIGR03706
1087448002610	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1087448002611	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1087448002612	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1087448002613	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1087448002614	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1087448002615	ABC-ATPase subunit  interface; other site
1087448002616	dimer interface [polypeptide binding]; other site
1087448002617	putative PBP binding regions; other site
1087448002618	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1087448002619	metal binding site 2 [ion binding]; metal-binding site
1087448002620	putative DNA binding helix; other site
1087448002621	metal binding site 1 [ion binding]; metal-binding site
1087448002622	dimer interface [polypeptide binding]; other site
1087448002623	structural Zn2+ binding site [ion binding]; other site
1087448002624	Uncharacterized conserved protein [Function unknown]; Region: COG0062
1087448002625	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
1087448002626	putative substrate binding site [chemical binding]; other site
1087448002627	putative ATP binding site [chemical binding]; other site
1087448002628	Uncharacterized conserved protein [Function unknown]; Region: COG5663
1087448002629	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
1087448002630	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1087448002631	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1087448002632	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
1087448002633	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1087448002634	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1087448002635	PhoU domain; Region: PhoU; pfam01895
1087448002636	PhoU domain; Region: PhoU; pfam01895
1087448002637	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
1087448002638	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
1087448002639	active site
1087448002640	Na/Ca binding site [ion binding]; other site
1087448002641	catalytic site [active]
1087448002642	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
1087448002643	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1087448002644	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1087448002645	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
1087448002646	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1087448002647	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1087448002648	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1087448002649	PBP superfamily domain; Region: PBP_like_2; cl17296
1087448002650	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
1087448002651	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1087448002652	dimer interface [polypeptide binding]; other site
1087448002653	conserved gate region; other site
1087448002654	putative PBP binding loops; other site
1087448002655	ABC-ATPase subunit interface; other site
1087448002656	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstA; COG0581
1087448002657	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1087448002658	dimer interface [polypeptide binding]; other site
1087448002659	conserved gate region; other site
1087448002660	putative PBP binding loops; other site
1087448002661	ABC-ATPase subunit interface; other site
1087448002662	phosphate transporter ATP-binding protein; Provisional; Region: PRK14238
1087448002663	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1087448002664	Walker A/P-loop; other site
1087448002665	ATP binding site [chemical binding]; other site
1087448002666	Q-loop/lid; other site
1087448002667	ABC transporter signature motif; other site
1087448002668	Walker B; other site
1087448002669	D-loop; other site
1087448002670	H-loop/switch region; other site
1087448002671	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
1087448002672	PhoU domain; Region: PhoU; pfam01895
1087448002673	PhoU domain; Region: PhoU; pfam01895
1087448002674	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3330
1087448002675	Uncharacterized conserved protein [Function unknown]; Region: COG1543
1087448002676	N-terminal catalytic domain of  alpha-amylase ( AmyC ) and similar proteins; Region: GH57N_AmyC_like; cd10792
1087448002677	active site
1087448002678	substrate binding site [chemical binding]; other site
1087448002679	catalytic site [active]
1087448002680	Domain of unknown function (DUF1957); Region: DUF1957; pfam09210
1087448002681	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1087448002682	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
1087448002683	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
1087448002684	Integral membrane protein DUF92; Region: DUF92; pfam01940
1087448002685	L-lactate dehydrogenase; Reviewed; Region: ldh; PRK00066
1087448002686	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
1087448002687	NAD binding site [chemical binding]; other site
1087448002688	dimer interface [polypeptide binding]; other site
1087448002689	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1087448002690	substrate binding site [chemical binding]; other site
1087448002691	pseudaminic acid biosynthesis N-acetyl transferase; Region: PseH; TIGR03585
1087448002692	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1087448002693	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1087448002694	Coenzyme A binding pocket [chemical binding]; other site
1087448002695	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
1087448002696	M42 Peptidase, Endoglucanase-like subfamily; Region: M42_glucanase_like; cd05657
1087448002697	putative oligomer interface [polypeptide binding]; other site
1087448002698	putative active site [active]
1087448002699	metal binding site [ion binding]; metal-binding site
1087448002700	Bacterial protein of unknown function (DUF910); Region: DUF910; pfam06014
1087448002701	ROK family protein (putative glucokinase); Region: ROK_glcA_fam; TIGR00744
1087448002702	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1087448002703	nucleotide binding site [chemical binding]; other site
1087448002704	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
1087448002705	Sulfatase; Region: Sulfatase; pfam00884
1087448002706	Protein of unknown function (DUF2759); Region: DUF2759; pfam10958
1087448002707	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1087448002708	Protein of unknown function (DUF2626); Region: DUF2626; pfam11117
1087448002709	Arsenate Reductase (ArsC) family, Spx subfamily; Spx is a unique RNA polymerase (RNAP)-binding protein present in bacilli and some mollicutes. It inhibits transcription by binding to the C-terminal domain of the alpha subunit of RNAP, disrupting complex...; Region: ArsC_Spx; cd03032
1087448002710	ArsC family; Region: ArsC; pfam03960
1087448002711	putative catalytic residues [active]
1087448002712	thiol/disulfide switch; other site
1087448002713	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1087448002714	Walker A motif; other site
1087448002715	ATP binding site [chemical binding]; other site
1087448002716	Walker B motif; other site
1087448002717	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1087448002718	Competence protein ComGC [Intracellular trafficking and secretion]; Region: ComGC; COG4537
1087448002719	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
1087448002720	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
1087448002721	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1087448002722	Shikimate kinase; Region: SKI; pfam01202
1087448002723	ADP binding site [chemical binding]; other site
1087448002724	magnesium binding site [ion binding]; other site
1087448002725	putative shikimate binding site; other site
1087448002726	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
1087448002727	Sarcosine oxidase, gamma subunit family; Region: SoxG; cl01893
1087448002728	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
1087448002729	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain [Amino acid transport and metabolism]; Region: GcvP; COG0403
1087448002730	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1087448002731	tetramer interface [polypeptide binding]; other site
1087448002732	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1087448002733	catalytic residue [active]
1087448002734	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1087448002735	tetramer interface [polypeptide binding]; other site
1087448002736	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1087448002737	catalytic residue [active]
1087448002738	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1087448002739	active site residue [active]
1087448002740	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
1087448002741	manganese transport transcriptional regulator; Provisional; Region: PRK03902
1087448002742	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1087448002743	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
1087448002744	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1087448002745	active site
1087448002746	Predicted metal-dependent enzyme [General function prediction only]; Region: COG3872
1087448002747	Dehydroquinase class II; Region: DHquinase_II; pfam01220
1087448002748	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
1087448002749	active site
1087448002750	trimer interface [polypeptide binding]; other site
1087448002751	dimer interface [polypeptide binding]; other site
1087448002752	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1087448002753	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1087448002754	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
1087448002755	active site
1087448002756	elongation factor P; Validated; Region: PRK00529
1087448002757	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1087448002758	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1087448002759	RNA binding site [nucleotide binding]; other site
1087448002760	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1087448002761	RNA binding site [nucleotide binding]; other site
1087448002762	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
1087448002763	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1087448002764	carboxyltransferase (CT) interaction site; other site
1087448002765	biotinylation site [posttranslational modification]; other site
1087448002766	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
1087448002767	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1087448002768	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1087448002769	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1087448002770	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
1087448002771	putative RNA binding site [nucleotide binding]; other site
1087448002772	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14190
1087448002773	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1087448002774	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1087448002775	homodimer interface [polypeptide binding]; other site
1087448002776	NADP binding site [chemical binding]; other site
1087448002777	substrate binding site [chemical binding]; other site
1087448002778	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
1087448002779	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1087448002780	generic binding surface II; other site
1087448002781	generic binding surface I; other site
1087448002782	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
1087448002783	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1087448002784	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1087448002785	substrate binding pocket [chemical binding]; other site
1087448002786	chain length determination region; other site
1087448002787	substrate-Mg2+ binding site; other site
1087448002788	catalytic residues [active]
1087448002789	aspartate-rich region 1; other site
1087448002790	active site lid residues [active]
1087448002791	aspartate-rich region 2; other site
1087448002792	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
1087448002793	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1087448002794	TPP-binding site; other site
1087448002795	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1087448002796	PYR/PP interface [polypeptide binding]; other site
1087448002797	dimer interface [polypeptide binding]; other site
1087448002798	TPP binding site [chemical binding]; other site
1087448002799	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1087448002800	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
1087448002801	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1087448002802	RNA binding surface [nucleotide binding]; other site
1087448002803	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
1087448002804	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1087448002805	arginine repressor; Provisional; Region: PRK04280
1087448002806	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1087448002807	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
1087448002808	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1087448002809	Walker A/P-loop; other site
1087448002810	ATP binding site [chemical binding]; other site
1087448002811	Q-loop/lid; other site
1087448002812	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1087448002813	Q-loop/lid; other site
1087448002814	ABC transporter signature motif; other site
1087448002815	Walker B; other site
1087448002816	D-loop; other site
1087448002817	H-loop/switch region; other site
1087448002818	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1087448002819	sporulation transcription factor Spo0A; Region: spore_0_A; TIGR02875
1087448002820	active site
1087448002821	phosphorylation site [posttranslational modification]
1087448002822	intermolecular recognition site; other site
1087448002823	dimerization interface [polypeptide binding]; other site
1087448002824	Sporulation initiation factor Spo0A C terminal; Region: Spo0A_C; pfam08769
1087448002825	Protein of unknown function (DUF2627); Region: DUF2627; pfam11118
1087448002826	PAS domain S-box; Region: sensory_box; TIGR00229
1087448002827	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1087448002828	putative active site [active]
1087448002829	heme pocket [chemical binding]; other site
1087448002830	psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974
1087448002831	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1087448002832	Walker A motif; other site
1087448002833	ATP binding site [chemical binding]; other site
1087448002834	Walker B motif; other site
1087448002835	arginine finger; other site
1087448002836	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1087448002837	phosphate butyryltransferase; Validated; Region: PRK07742
1087448002838	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
1087448002839	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1087448002840	NAD(P) binding domain of leucine dehydrogenase, phenylalanine dehydrogenase, and valine dehydrogenase; Region: NAD_bind_Leu_Phe_Val_DH; cd01075
1087448002841	NAD binding site [chemical binding]; other site
1087448002842	Phe binding site; other site
1087448002843	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1087448002844	nucleotide binding site [chemical binding]; other site
1087448002845	Acetokinase family; Region: Acetate_kinase; cl17229
1087448002846	dihydrolipoamide dehydrogenase; Validated; Region: PRK05976
1087448002847	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1087448002848	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1087448002849	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_x; TIGR03181
1087448002850	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
1087448002851	tetramer interface [polypeptide binding]; other site
1087448002852	TPP-binding site [chemical binding]; other site
1087448002853	heterodimer interface [polypeptide binding]; other site
1087448002854	phosphorylation loop region [posttranslational modification]
1087448002855	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
1087448002856	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
1087448002857	alpha subunit interface [polypeptide binding]; other site
1087448002858	TPP binding site [chemical binding]; other site
1087448002859	heterodimer interface [polypeptide binding]; other site
1087448002860	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1087448002861	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
1087448002862	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1087448002863	E3 interaction surface; other site
1087448002864	lipoyl attachment site [posttranslational modification]; other site
1087448002865	e3 binding domain; Region: E3_binding; pfam02817
1087448002866	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1087448002867	anthranilate synthase component I; Provisional; Region: PRK13570
1087448002868	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1087448002869	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1087448002870	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
1087448002871	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1087448002872	glutamine binding [chemical binding]; other site
1087448002873	catalytic triad [active]
1087448002874	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
1087448002875	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1087448002876	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1087448002877	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
1087448002878	active site
1087448002879	ribulose/triose binding site [chemical binding]; other site
1087448002880	phosphate binding site [ion binding]; other site
1087448002881	substrate (anthranilate) binding pocket [chemical binding]; other site
1087448002882	product (indole) binding pocket [chemical binding]; other site
1087448002883	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
1087448002884	active site
1087448002885	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
1087448002886	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1087448002887	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1087448002888	catalytic residue [active]
1087448002889	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
1087448002890	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
1087448002891	substrate binding site [chemical binding]; other site
1087448002892	active site
1087448002893	catalytic residues [active]
1087448002894	heterodimer interface [polypeptide binding]; other site
1087448002895	NTF2-like N-terminal transpeptidase domain; Region: MecA_N; pfam05223
1087448002896	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
1087448002897	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1087448002898	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1087448002899	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
1087448002900	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1087448002901	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1087448002902	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
1087448002903	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1087448002904	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1087448002905	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1087448002906	ABC transporter; Region: ABC_tran_2; pfam12848
1087448002907	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1087448002908	Predicted secreted protein [Function unknown]; Region: COG4086
1087448002909	Protein of unknown function (DUF1002); Region: DUF1002; pfam06207
1087448002910	Putative transcription activator [Transcription]; Region: TenA; COG0819
1087448002911	Sporulation control protein [General function prediction only]; Region: Spo0M; COG4326
1087448002912	SpoOM protein; Region: Spo0M; pfam07070
1087448002913	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1087448002914	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1087448002915	S-adenosylmethionine binding site [chemical binding]; other site
1087448002916	Disulphide isomerase; Region: Disulph_isomer; pfam06491
1087448002917	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1087448002918	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1087448002919	substrate binding pocket [chemical binding]; other site
1087448002920	membrane-bound complex binding site; other site
1087448002921	hinge residues; other site
1087448002922	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1087448002923	dimer interface [polypeptide binding]; other site
1087448002924	conserved gate region; other site
1087448002925	putative PBP binding loops; other site
1087448002926	ABC-ATPase subunit interface; other site
1087448002927	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1087448002928	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1087448002929	Walker A/P-loop; other site
1087448002930	ATP binding site [chemical binding]; other site
1087448002931	Q-loop/lid; other site
1087448002932	ABC transporter signature motif; other site
1087448002933	Walker B; other site
1087448002934	D-loop; other site
1087448002935	H-loop/switch region; other site
1087448002936	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
1087448002937	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1087448002938	Zn2+ binding site [ion binding]; other site
1087448002939	Mg2+ binding site [ion binding]; other site
1087448002940	Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]; Region: COG0428; cl00437
1087448002941	short chain dehydrogenase; Provisional; Region: PRK07677
1087448002942	Trans-2-enoyl-CoA reductase (TER) and 2,4-dienoyl-CoA reductase (DECR), atypical (a) SDR; Region: TER_DECR_SDR_a; cd05369
1087448002943	NAD(P) binding site [chemical binding]; other site
1087448002944	substrate binding site [chemical binding]; other site
1087448002945	homotetramer interface [polypeptide binding]; other site
1087448002946	active site
1087448002947	homodimer interface [polypeptide binding]; other site
1087448002948	putative manganese-dependent inorganic pyrophosphatase; Provisional; Region: PRK05427
1087448002949	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
1087448002950	DHHA2 domain; Region: DHHA2; pfam02833
1087448002951	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; pfam01832
1087448002952	Predicted membrane protein [Function unknown]; Region: COG4129
1087448002953	Bacterial protein of unknown function (DUF939); Region: DUF939; pfam06081
1087448002954	DUF939 C-terminal domain; Region: DUF939_C; pfam11728
1087448002955	M20 Peptidase T like enzymes specifically cleave tripeptides; Region: M20_peptT_like; cd05683
1087448002956	peptidase T-like protein; Region: PepT-like; TIGR01883
1087448002957	metal binding site [ion binding]; metal-binding site
1087448002958	putative dimer interface [polypeptide binding]; other site
1087448002959	ribonuclease Z; Region: RNase_Z; TIGR02651
1087448002960	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1087448002961	ABC transporter signature motif; other site
1087448002962	Walker B; other site
1087448002963	D-loop; other site
1087448002964	H-loop/switch region; other site
1087448002965	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
1087448002966	ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones]; Region: CcmA; COG4133
1087448002967	Walker A/P-loop; other site
1087448002968	ATP binding site [chemical binding]; other site
1087448002969	Q-loop/lid; other site
1087448002970	ABC transporter signature motif; other site
1087448002971	Walker B; other site
1087448002972	D-loop; other site
1087448002973	H-loop/switch region; other site
1087448002974	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
1087448002975	classical (c) SDRs; Region: SDR_c; cd05233
1087448002976	NAD(P) binding site [chemical binding]; other site
1087448002977	active site
1087448002978	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1087448002979	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1087448002980	EamA-like transporter family; Region: EamA; pfam00892
1087448002981	DNA topoisomerase III; Provisional; Region: PRK07726
1087448002982	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
1087448002983	active site
1087448002984	putative interdomain interaction site [polypeptide binding]; other site
1087448002985	putative metal-binding site [ion binding]; other site
1087448002986	putative nucleotide binding site [chemical binding]; other site
1087448002987	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1087448002988	domain I; other site
1087448002989	DNA binding groove [nucleotide binding]
1087448002990	phosphate binding site [ion binding]; other site
1087448002991	domain II; other site
1087448002992	domain III; other site
1087448002993	nucleotide binding site [chemical binding]; other site
1087448002994	catalytic site [active]
1087448002995	domain IV; other site
1087448002996	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1087448002997	C-terminal repeat of topoisomerase; Region: Toprim_Crpt; pfam13342
1087448002998	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1087448002999	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
1087448003000	ABC-2 type transporter; Region: ABC2_membrane; cl17235
1087448003001	ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system; Region: PQQ_ABC_ATP; TIGR03864
1087448003002	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1087448003003	Walker A/P-loop; other site
1087448003004	ATP binding site [chemical binding]; other site
1087448003005	Q-loop/lid; other site
1087448003006	ABC transporter signature motif; other site
1087448003007	Walker B; other site
1087448003008	D-loop; other site
1087448003009	H-loop/switch region; other site
1087448003010	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1087448003011	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1087448003012	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1087448003013	FAD binding domain; Region: FAD_binding_4; pfam01565
1087448003014	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1087448003015	dimer interface [polypeptide binding]; other site
1087448003016	conserved gate region; other site
1087448003017	ABC-ATPase subunit interface; other site
1087448003018	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1087448003019	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
1087448003020	Protein of unknown function DUF58; Region: DUF58; pfam01882
1087448003021	MoxR-like ATPases [General function prediction only]; Region: COG0714
1087448003022	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1087448003023	Walker A motif; other site
1087448003024	ATP binding site [chemical binding]; other site
1087448003025	Walker B motif; other site
1087448003026	arginine finger; other site
1087448003027	biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; Region: BVR-B_like_SDR_a; cd05244
1087448003028	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1087448003029	NAD binding site [chemical binding]; other site
1087448003030	substrate binding site [chemical binding]; other site
1087448003031	putative active site [active]
1087448003032	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
1087448003033	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
1087448003034	active site
1087448003035	Na/Ca binding site [ion binding]; other site
1087448003036	catalytic site [active]
1087448003037	Endonuclease I; Region: Endonuclease_1; pfam04231
1087448003038	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1087448003039	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1087448003040	putative active site [active]
1087448003041	Response regulator receiver domain; Region: Response_reg; pfam00072
1087448003042	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1087448003043	active site
1087448003044	phosphorylation site [posttranslational modification]
1087448003045	intermolecular recognition site; other site
1087448003046	dimerization interface [polypeptide binding]; other site
1087448003047	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
1087448003048	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1087448003049	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
1087448003050	Cl binding site [ion binding]; other site
1087448003051	oligomer interface [polypeptide binding]; other site
1087448003052	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cl00086
1087448003053	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cl00086
1087448003054	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
1087448003055	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1087448003056	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1087448003057	active site
1087448003058	phosphorylation site [posttranslational modification]
1087448003059	intermolecular recognition site; other site
1087448003060	dimerization interface [polypeptide binding]; other site
1087448003061	NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; Provisional; Region: PLN00412
1087448003062	NADP+-dependent non-phosphorylating glyceraldehyde 3-phosphate dehydrogenase and ALDH family 11; Region: ALDH_F11_NP-GAPDH; cd07082
1087448003063	tetrameric interface [polypeptide binding]; other site
1087448003064	activator binding site; other site
1087448003065	NADP binding site [chemical binding]; other site
1087448003066	substrate binding site [chemical binding]; other site
1087448003067	catalytic residues [active]
1087448003068	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1087448003069	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
1087448003070	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1087448003071	NAD(P) binding site [chemical binding]; other site
1087448003072	active site
1087448003073	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4134
1087448003074	hypothetical protein; Provisional; Region: PRK11622
1087448003075	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1087448003076	dimer interface [polypeptide binding]; other site
1087448003077	conserved gate region; other site
1087448003078	putative PBP binding loops; other site
1087448003079	ABC-ATPase subunit interface; other site
1087448003080	ABC transporter; Region: ABC_tran; pfam00005
1087448003081	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1087448003082	Q-loop/lid; other site
1087448003083	ABC transporter signature motif; other site
1087448003084	Walker B; other site
1087448003085	D-loop; other site
1087448003086	H-loop/switch region; other site
1087448003087	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
1087448003088	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_33; cd04692
1087448003089	nudix motif; other site
1087448003090	Predicted transcriptional regulators [Transcription]; Region: COG1695
1087448003091	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1087448003092	Virulence activator alpha C-term; Region: Vir_act_alpha_C; pfam10400
1087448003093	Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein; Region: GATase1_Hsp31_like; cd03141
1087448003094	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
1087448003095	potential catalytic triad [active]
1087448003096	conserved cys residue [active]
1087448003097	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1087448003098	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1087448003099	active site
1087448003100	catalytic tetrad [active]
1087448003101	nudix-type nucleoside diphosphatase, YffH/AdpP family; Region: TIGR00052
1087448003102	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1087448003103	dimer interface [polypeptide binding]; other site
1087448003104	ADP-ribose binding site [chemical binding]; other site
1087448003105	active site
1087448003106	nudix motif; other site
1087448003107	metal binding site [ion binding]; metal-binding site
1087448003108	ferric uptake regulator; Provisional; Region: fur; PRK09462
1087448003109	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1087448003110	metal binding site 2 [ion binding]; metal-binding site
1087448003111	putative DNA binding helix; other site
1087448003112	metal binding site 1 [ion binding]; metal-binding site
1087448003113	dimer interface [polypeptide binding]; other site
1087448003114	structural Zn2+ binding site [ion binding]; other site
1087448003115	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1087448003116	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
1087448003117	active site
1087448003118	DNA binding site [nucleotide binding]
1087448003119	Int/Topo IB signature motif; other site
1087448003120	phosphopentomutase; Provisional; Region: PRK05362
1087448003121	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
1087448003122	purine nucleoside phosphorylase; Provisional; Region: PRK08202
1087448003123	pyrimidine-nucleoside phosphorylase; Reviewed; Region: PRK06078
1087448003124	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1087448003125	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1087448003126	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
1087448003127	Microcin C7 self-immunity protein determines resistance to exogenous microcin C7; Region: Peptidase_S66_mccF_like; cd07062
1087448003128	putative dimer interface [polypeptide binding]; other site
1087448003129	catalytic triad [active]
1087448003130	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
1087448003131	active site
1087448003132	intracellular protease, PfpI family; Region: PfpI; TIGR01382
1087448003133	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
1087448003134	proposed catalytic triad [active]
1087448003135	conserved cys residue [active]
1087448003136	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
1087448003137	Domain of unknown function (DUF309); Region: DUF309; pfam03745
1087448003138	segregation and condensation protein A; Reviewed; Region: scpA; PRK00104
1087448003139	segregation and condensation protein B; Reviewed; Region: scpB; PRK00135
1087448003140	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1087448003141	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1087448003142	RNA binding surface [nucleotide binding]; other site
1087448003143	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
1087448003144	active site
1087448003145	periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily; Region: dsbE; TIGR00385
1087448003146	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1087448003147	catalytic residues [active]
1087448003148	ResB protein required for cytochrome c biosynthesis [Posttranslational modification, protein turnover, chaperones]; Region: ResB; cl09125
1087448003149	ResB-like family; Region: ResB; pfam05140
1087448003150	Cytochrome C assembly protein; Region: Cytochrom_C_asm; cl00504
1087448003151	Cytochrome C assembly protein; Region: Cytochrom_C_asm; cl00504
1087448003152	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1087448003153	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1087448003154	active site
1087448003155	phosphorylation site [posttranslational modification]
1087448003156	intermolecular recognition site; other site
1087448003157	dimerization interface [polypeptide binding]; other site
1087448003158	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1087448003159	DNA binding site [nucleotide binding]
1087448003160	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: VicK; COG5002
1087448003161	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1087448003162	dimerization interface [polypeptide binding]; other site
1087448003163	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1087448003164	dimer interface [polypeptide binding]; other site
1087448003165	phosphorylation site [posttranslational modification]
1087448003166	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1087448003167	ATP binding site [chemical binding]; other site
1087448003168	Mg2+ binding site [ion binding]; other site
1087448003169	G-X-G motif; other site
1087448003170	Cobalamin adenosyltransferase; Region: Cob_adeno_trans; pfam01923
1087448003171	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1087448003172	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1087448003173	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1087448003174	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1087448003175	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1087448003176	classical (c) SDRs; Region: SDR_c; cd05233
1087448003177	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
1087448003178	NAD(P) binding site [chemical binding]; other site
1087448003179	active site
1087448003180	Protein of unknown function (DUF3388); Region: DUF3388; pfam11868
1087448003181	Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown]; Region: COG1426
1087448003182	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1087448003183	non-specific DNA binding site [nucleotide binding]; other site
1087448003184	salt bridge; other site
1087448003185	sequence-specific DNA binding site [nucleotide binding]; other site
1087448003186	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
1087448003187	competence damage-inducible protein A; Provisional; Region: PRK00549
1087448003188	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
1087448003189	putative MPT binding site; other site
1087448003190	Competence-damaged protein; Region: CinA; pfam02464
1087448003191	recombinase A; Provisional; Region: recA; PRK09354
1087448003192	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1087448003193	hexamer interface [polypeptide binding]; other site
1087448003194	Walker A motif; other site
1087448003195	ATP binding site [chemical binding]; other site
1087448003196	Walker B motif; other site
1087448003197	phosphodiesterase; Provisional; Region: PRK12704
1087448003198	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1087448003199	Zn2+ binding site [ion binding]; other site
1087448003200	Mg2+ binding site [ion binding]; other site
1087448003201	Deinococcus radiodurans DR1281 and related proteins, metallophosphatase domain; Region: MPP_DR1281; cd07382
1087448003202	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1087448003203	putative active site [active]
1087448003204	metal binding site [ion binding]; metal-binding site
1087448003205	homodimer binding site [polypeptide binding]; other site
1087448003206	Stage V sporulation protein S (SpoVS); Region: SpoVS; pfam04232
1087448003207	2-oxoacid:acceptor oxidoreductase, alpha subunit; Region: OAFO_sf; TIGR03710
1087448003208	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
1087448003209	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1087448003210	dimer interface [polypeptide binding]; other site
1087448003211	PYR/PP interface [polypeptide binding]; other site
1087448003212	TPP binding site [chemical binding]; other site
1087448003213	substrate binding site [chemical binding]; other site
1087448003214	2-oxoglutarate ferredoxin oxidoreductase subunit beta; Reviewed; Region: PRK11867
1087448003215	Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor. In the TCA cycle, OGFOR...; Region: TPP_OGFOR; cd03375
1087448003216	TPP-binding site [chemical binding]; other site
1087448003217	Pyruvate ferredoxin oxidoreductase beta subunit C terminal; Region: PFO_beta_C; pfam12367
1087448003218	Threonine dehydrogenase; Region: TDH; cd05281
1087448003219	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
1087448003220	structural Zn binding site [ion binding]; other site
1087448003221	catalytic Zn binding site [ion binding]; other site
1087448003222	tetramer interface [polypeptide binding]; other site
1087448003223	NADP binding site [chemical binding]; other site
1087448003224	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1087448003225	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1087448003226	substrate-cofactor binding pocket; other site
1087448003227	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1087448003228	catalytic residue [active]
1087448003229	ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CeuD; COG4604
1087448003230	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1087448003231	Walker A/P-loop; other site
1087448003232	ATP binding site [chemical binding]; other site
1087448003233	Q-loop/lid; other site
1087448003234	ABC transporter signature motif; other site
1087448003235	Walker B; other site
1087448003236	D-loop; other site
1087448003237	H-loop/switch region; other site
1087448003238	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
1087448003239	ABC-ATPase subunit  interface; other site
1087448003240	dimer interface [polypeptide binding]; other site
1087448003241	putative PBP binding regions; other site
1087448003242	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1087448003243	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1087448003244	ABC-ATPase subunit  interface; other site
1087448003245	dimer interface [polypeptide binding]; other site
1087448003246	putative PBP binding regions; other site
1087448003247	ABC-type enterochelin transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: CeuA; COG4607
1087448003248	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1087448003249	intersubunit interface [polypeptide binding]; other site
1087448003250	Protein of unknown function (DUF3153); Region: DUF3153; pfam11353
1087448003251	Alpha/beta hydrolase of unknown function (DUF915); Region: DUF915; pfam06028
1087448003252	PGAP1-like protein; Region: PGAP1; pfam07819
1087448003253	C-3',4' desaturase CrtD; Region: desat_CrtD; TIGR02733
1087448003254	Protein of unknown function (DUF445); Region: DUF445; pfam04286
1087448003255	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1087448003256	endonuclease III; Region: ENDO3c; smart00478
1087448003257	minor groove reading motif; other site
1087448003258	helix-hairpin-helix signature motif; other site
1087448003259	substrate binding pocket [chemical binding]; other site
1087448003260	active site
1087448003261	Predicted membrane protein [Function unknown]; Region: COG4550
1087448003262	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
1087448003263	MutS domain I; Region: MutS_I; pfam01624
1087448003264	MutS domain II; Region: MutS_II; pfam05188
1087448003265	MutS domain III; Region: MutS_III; pfam05192
1087448003266	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
1087448003267	Walker A/P-loop; other site
1087448003268	ATP binding site [chemical binding]; other site
1087448003269	Q-loop/lid; other site
1087448003270	ABC transporter signature motif; other site
1087448003271	Walker B; other site
1087448003272	D-loop; other site
1087448003273	H-loop/switch region; other site
1087448003274	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
1087448003275	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1087448003276	ATP binding site [chemical binding]; other site
1087448003277	Mg2+ binding site [ion binding]; other site
1087448003278	G-X-G motif; other site
1087448003279	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
1087448003280	ATP binding site [chemical binding]; other site
1087448003281	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
1087448003282	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
1087448003283	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
1087448003284	AAA domain; Region: AAA_18; pfam13238
1087448003285	GAF domain; Region: GAF_3; pfam13492
1087448003286	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1087448003287	dimer interface [polypeptide binding]; other site
1087448003288	phosphorylation site [posttranslational modification]
1087448003289	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1087448003290	ATP binding site [chemical binding]; other site
1087448003291	Mg2+ binding site [ion binding]; other site
1087448003292	G-X-G motif; other site
1087448003293	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK14704
1087448003294	Class III ribonucleotide reductase; Region: RNR_III; cd01675
1087448003295	effector binding site; other site
1087448003296	active site
1087448003297	Zn binding site [ion binding]; other site
1087448003298	glycine loop; other site
1087448003299	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
1087448003300	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1087448003301	FeS/SAM binding site; other site
1087448003302	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1087448003303	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1087448003304	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1087448003305	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1087448003306	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1087448003307	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
1087448003308	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1087448003309	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1087448003310	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
1087448003311	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1087448003312	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1087448003313	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1087448003314	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1087448003315	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1087448003316	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1087448003317	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1087448003318	putative substrate binding site [chemical binding]; other site
1087448003319	putative ATP binding site [chemical binding]; other site
1087448003320	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
1087448003321	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1087448003322	active site
1087448003323	phosphorylation site [posttranslational modification]
1087448003324	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1087448003325	active site
1087448003326	P-loop; other site
1087448003327	phosphorylation site [posttranslational modification]
1087448003328	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1087448003329	Predicted membrane protein [Function unknown]; Region: COG4129
1087448003330	Bacterial protein of unknown function (DUF939); Region: DUF939; pfam06081
1087448003331	phenylalanine 4-monooxygenase; Provisional; Region: PRK14056
1087448003332	Biopterin-dependent aromatic amino acid hydroxylase; a family of non-heme, iron(II)-dependent enzymes that includes prokaryotic and eukaryotic phenylalanine-4-hydroxylase (PheOH), eukaryotic tyrosine hydroxylase (TyrOH) and eukaryotic tryptophan...; Region: arom_aa_hydroxylase; cd00361
1087448003333	cofactor binding site; other site
1087448003334	metal binding site [ion binding]; metal-binding site
1087448003335	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain superfamily; Region: NTP-PPase; cl16941
1087448003336	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1087448003337	DNA binding site [nucleotide binding]
1087448003338	active site
1087448003339	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1087448003340	Cation efflux family; Region: Cation_efflux; pfam01545
1087448003341	Uncharacterized stress protein (general stress protein 26) [General function prediction only]; Region: COG3871
1087448003342	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
1087448003343	luciferase family oxidoreductase, group 1; Region: oxido_grp_1; TIGR03558
1087448003344	probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858
1087448003345	H+ Antiporter protein; Region: 2A0121; TIGR00900
1087448003346	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1087448003347	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1087448003348	non-specific DNA binding site [nucleotide binding]; other site
1087448003349	salt bridge; other site
1087448003350	sequence-specific DNA binding site [nucleotide binding]; other site
1087448003351	Bacterial SH3 domain; Region: SH3_3; pfam08239
1087448003352	Bacterial SH3 domain; Region: SH3_3; pfam08239
1087448003353	Bacterial SH3 domain; Region: SH3_3; pfam08239
1087448003354	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1087448003355	NlpC/P60 family; Region: NLPC_P60; pfam00877
1087448003356	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1087448003357	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1087448003358	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1087448003359	Walker A/P-loop; other site
1087448003360	ATP binding site [chemical binding]; other site
1087448003361	Q-loop/lid; other site
1087448003362	ABC transporter signature motif; other site
1087448003363	Walker B; other site
1087448003364	D-loop; other site
1087448003365	H-loop/switch region; other site
1087448003366	Protein of unknown function (DUF4003); Region: DUF4003; pfam13170
1087448003367	L-lysine 6-monooxygenase (NADPH-requiring); Region: K_oxygenase; pfam13434
1087448003368	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1087448003369	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1087448003370	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
1087448003371	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1087448003372	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1087448003373	protein binding site [polypeptide binding]; other site
1087448003374	Predicted membrane protein [Function unknown]; Region: COG4270
1087448003375	Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_YpmR_like; cd04506
1087448003376	active site
1087448003377	catalytic triad [active]
1087448003378	oxyanion hole [active]
1087448003379	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1087448003380	ATP-binding cassette domain of the bacitracin-resistance transporter; Region: ABC_BcrA_bacitracin_resist; cd03268
1087448003381	Walker A/P-loop; other site
1087448003382	ATP binding site [chemical binding]; other site
1087448003383	Q-loop/lid; other site
1087448003384	ABC transporter signature motif; other site
1087448003385	Walker B; other site
1087448003386	D-loop; other site
1087448003387	H-loop/switch region; other site
1087448003388	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
1087448003389	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
1087448003390	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1087448003391	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1087448003392	bacterial Hfq-like; Region: Hfq; cd01716
1087448003393	hexamer interface [polypeptide binding]; other site
1087448003394	Sm1 motif; other site
1087448003395	RNA binding site [nucleotide binding]; other site
1087448003396	Sm2 motif; other site
1087448003397	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1087448003398	active site
1087448003399	Int/Topo IB signature motif; other site
1087448003400	DNA binding site [nucleotide binding]
1087448003401	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
1087448003402	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
1087448003403	HflX GTPase family; Region: HflX; cd01878
1087448003404	G1 box; other site
1087448003405	GTP/Mg2+ binding site [chemical binding]; other site
1087448003406	Switch I region; other site
1087448003407	G2 box; other site
1087448003408	G3 box; other site
1087448003409	Switch II region; other site
1087448003410	G4 box; other site
1087448003411	G5 box; other site
1087448003412	Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion transport and metabolism]; Region: COG4100
1087448003413	Aluminium resistance protein; Region: Alum_res; pfam06838
1087448003414	Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators; Region: HTH_GlnR-like; cd01105
1087448003415	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1087448003416	DNA binding residues [nucleotide binding]
1087448003417	putative dimer interface [polypeptide binding]; other site
1087448003418	glutamine synthetase, type I; Region: GlnA; TIGR00653
1087448003419	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
1087448003420	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1087448003421	Branched-chain amino acid transport protein (AzlD); Region: AzlD; cl00735
1087448003422	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
1087448003423	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481
1087448003424	Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376
1087448003425	DAK2 domain; Region: Dak2; cl03685
1087448003426	phosphotransferase mannnose-specific family component IIA; Provisional; Region: PRK14484
1087448003427	glycerol kinase; Provisional; Region: glpK; PRK00047
1087448003428	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
1087448003429	N- and C-terminal domain interface [polypeptide binding]; other site
1087448003430	active site
1087448003431	MgATP binding site [chemical binding]; other site
1087448003432	catalytic site [active]
1087448003433	metal binding site [ion binding]; metal-binding site
1087448003434	glycerol binding site [chemical binding]; other site
1087448003435	homotetramer interface [polypeptide binding]; other site
1087448003436	homodimer interface [polypeptide binding]; other site
1087448003437	FBP binding site [chemical binding]; other site
1087448003438	protein IIAGlc interface [polypeptide binding]; other site
1087448003439	Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism]; Region: GlpF; COG0580
1087448003440	amphipathic channel; other site
1087448003441	Asn-Pro-Ala signature motifs; other site
1087448003442	Uncharacterized metal-binding protein (DUF2227); Region: DUF2227; pfam09988
1087448003443	LexA repressor; Validated; Region: PRK00215
1087448003444	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1087448003445	putative DNA binding site [nucleotide binding]; other site
1087448003446	putative Zn2+ binding site [ion binding]; other site
1087448003447	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1087448003448	Catalytic site [active]
1087448003449	cell division suppressor protein YneA; Provisional; Region: PRK14125
1087448003450	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1087448003451	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
1087448003452	catalytic residues [active]
1087448003453	catalytic nucleophile [active]
1087448003454	Bacterial protein of unknown function (DUF896); Region: DUF896; pfam05979
1087448003455	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
1087448003456	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1087448003457	TPP-binding site [chemical binding]; other site
1087448003458	dimer interface [polypeptide binding]; other site
1087448003459	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1087448003460	PYR/PP interface [polypeptide binding]; other site
1087448003461	dimer interface [polypeptide binding]; other site
1087448003462	TPP binding site [chemical binding]; other site
1087448003463	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1087448003464	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3763
1087448003465	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1087448003466	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
1087448003467	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1087448003468	Walker A/P-loop; other site
1087448003469	ATP binding site [chemical binding]; other site
1087448003470	Q-loop/lid; other site
1087448003471	ABC transporter signature motif; other site
1087448003472	Walker B; other site
1087448003473	D-loop; other site
1087448003474	H-loop/switch region; other site
1087448003475	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1087448003476	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1087448003477	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
1087448003478	Walker A/P-loop; other site
1087448003479	ATP binding site [chemical binding]; other site
1087448003480	Q-loop/lid; other site
1087448003481	ABC transporter signature motif; other site
1087448003482	Walker B; other site
1087448003483	D-loop; other site
1087448003484	H-loop/switch region; other site
1087448003485	Bacterial SH3 domain; Region: SH3_3; pfam08239
1087448003486	Bacterial SH3 domain; Region: SH3_3; pfam08239
1087448003487	3D domain; Region: 3D; cl01439
1087448003488	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
1087448003489	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; pfam02683
1087448003490	Protein of unknown function (DUF1453); Region: DUF1453; pfam07301
1087448003491	Protein of unknown function (DUF2621); Region: DUF2621; pfam11084
1087448003492	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_9; cd07245
1087448003493	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1087448003494	dimer interface [polypeptide binding]; other site
1087448003495	putative metal binding site [ion binding]; other site
1087448003496	Microcin C7 self-immunity protein determines resistance to exogenous microcin C7; Region: Peptidase_S66_mccF_like; cd07062
1087448003497	putative dimer interface [polypeptide binding]; other site
1087448003498	catalytic triad [active]
1087448003499	Transcriptional regulator; Region: Rrf2; cl17282
1087448003500	Rrf2 family protein; Region: rrf2_super; TIGR00738
1087448003501	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1087448003502	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1087448003503	putative substrate translocation pore; other site
1087448003504	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
1087448003505	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
1087448003506	G1 box; other site
1087448003507	putative GEF interaction site [polypeptide binding]; other site
1087448003508	GTP/Mg2+ binding site [chemical binding]; other site
1087448003509	Switch I region; other site
1087448003510	G2 box; other site
1087448003511	G3 box; other site
1087448003512	Switch II region; other site
1087448003513	G4 box; other site
1087448003514	G5 box; other site
1087448003515	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
1087448003516	Heat induced stress protein YflT; Region: YflT; pfam11181
1087448003517	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1087448003518	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
1087448003519	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
1087448003520	putative uracil/xanthine transporter; Provisional; Region: PRK11412
1087448003521	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1087448003522	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1087448003523	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1087448003524	dimerization interface [polypeptide binding]; other site
1087448003525	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
1087448003526	hypothetical protein; Reviewed; Region: PRK09588
1087448003527	Helix-turn-helix domain; Region: HTH_38; pfam13936
1087448003528	Winged helix-turn helix; Region: HTH_29; pfam13551
1087448003529	Integrase core domain; Region: rve; pfam00665
1087448003530	SMI1 / KNR4 family; Region: SMI1_KNR4; smart00860
1087448003531	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1087448003532	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1087448003533	active site
1087448003534	metal binding site [ion binding]; metal-binding site
1087448003535	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1087448003536	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1087448003537	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1087448003538	Isochorismatase family; Region: Isochorismatase; pfam00857
1087448003539	catalytic triad [active]
1087448003540	conserved cis-peptide bond; other site
1087448003541	Predicted flavoprotein [General function prediction only]; Region: COG0431
1087448003542	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1087448003543	N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_N_like; cd08346
1087448003544	C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_C_like; cd08347
1087448003545	Zn binding site [ion binding]; other site
1087448003546	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1087448003547	MarR family; Region: MarR; pfam01047
1087448003548	MarR family; Region: MarR_2; cl17246
1087448003549	Esterase/lipase [General function prediction only]; Region: COG1647
1087448003550	Haemolysin E (HlyE); Region: HlyE; cl11627
1087448003551	aconitate hydratase; Validated; Region: PRK09277
1087448003552	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
1087448003553	substrate binding site [chemical binding]; other site
1087448003554	ligand binding site [chemical binding]; other site
1087448003555	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
1087448003556	substrate binding site [chemical binding]; other site
1087448003557	Protein of unknown function (DUF3939); Region: DUF3939; pfam13075
1087448003558	stage V sporulation protein K; Region: spore_V_K; TIGR02881
1087448003559	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1087448003560	Walker A motif; other site
1087448003561	ATP binding site [chemical binding]; other site
1087448003562	Walker B motif; other site
1087448003563	arginine finger; other site
1087448003564	stage V sporulation protein K; Region: spore_V_K; TIGR02881
1087448003565	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1087448003566	Walker A motif; other site
1087448003567	ATP binding site [chemical binding]; other site
1087448003568	Walker B motif; other site
1087448003569	arginine finger; other site
1087448003570	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1087448003571	active site
1087448003572	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: VanY; COG1876
1087448003573	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
1087448003574	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
1087448003575	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1087448003576	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
1087448003577	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1087448003578	Uncharacterized protein involved in copper resistance [Inorganic ion transport and metabolism]; Region: CutC; COG3142
1087448003579	Protein of unknown function (DUF975); Region: DUF975; cl10504
1087448003580	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
1087448003581	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1087448003582	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1087448003583	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1087448003584	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1087448003585	Walker A/P-loop; other site
1087448003586	ATP binding site [chemical binding]; other site
1087448003587	Q-loop/lid; other site
1087448003588	ABC transporter signature motif; other site
1087448003589	Walker B; other site
1087448003590	D-loop; other site
1087448003591	H-loop/switch region; other site
1087448003592	Uncharacterized BCR, YaiI/YqxD family COG1671; Region: DUF188; cl00727
1087448003593	GAF domain; Region: GAF_3; pfam13492
1087448003594	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
1087448003595	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1087448003596	dimer interface [polypeptide binding]; other site
1087448003597	phosphorylation site [posttranslational modification]
1087448003598	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1087448003599	ATP binding site [chemical binding]; other site
1087448003600	Mg2+ binding site [ion binding]; other site
1087448003601	G-X-G motif; other site
1087448003602	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1087448003603	GAF domain; Region: GAF_2; pfam13185
1087448003604	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1087448003605	metal binding site [ion binding]; metal-binding site
1087448003606	active site
1087448003607	I-site; other site
1087448003608	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1087448003609	Domain of unknown function (DUF1836); Region: DUF1836; pfam08876
1087448003610	Predicted membrane protein, hemolysin III homolog [General function prediction only]; Region: COG1272
1087448003611	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
1087448003612	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1087448003613	Probable transposase; Region: OrfB_IS605; pfam01385
1087448003614	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
1087448003615	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
1087448003616	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
1087448003617	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
1087448003618	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1087448003619	active site
1087448003620	dimer interface [polypeptide binding]; other site
1087448003621	Predicted membrane protein [Function unknown]; Region: COG3766
1087448003622	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
1087448003623	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
1087448003624	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1087448003625	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1087448003626	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1087448003627	metal binding site [ion binding]; metal-binding site
1087448003628	active site
1087448003629	I-site; other site
1087448003630	putative acyltransferase; Provisional; Region: PRK05790
1087448003631	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1087448003632	dimer interface [polypeptide binding]; other site
1087448003633	active site
1087448003634	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1087448003635	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1087448003636	Walker A/P-loop; other site
1087448003637	ATP binding site [chemical binding]; other site
1087448003638	Q-loop/lid; other site
1087448003639	ABC transporter signature motif; other site
1087448003640	Walker B; other site
1087448003641	D-loop; other site
1087448003642	H-loop/switch region; other site
1087448003643	ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism]; Region: AbcD; COG2011
1087448003644	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1087448003645	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1087448003646	Branched-chain amino acid transport protein; Region: Branch_AA_trans; pfam05525
1087448003647	Glycerol dehydrogenase and related enzymes [Energy production and conversion]; Region: GldA; COG0371
1087448003648	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
1087448003649	dimer interface [polypeptide binding]; other site
1087448003650	active site
1087448003651	metal binding site [ion binding]; metal-binding site
1087448003652	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
1087448003653	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1087448003654	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
1087448003655	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1087448003656	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1087448003657	Bacterial SH3 domain; Region: SH3_3; pfam08239
1087448003658	Bacterial SH3 domain; Region: SH3_3; pfam08239
1087448003659	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1087448003660	Peptidase family M23; Region: Peptidase_M23; pfam01551
1087448003661	Uncharacterized protein with a bacterial SH3 domain homologue [Function unknown]; Region: COG4991
1087448003662	Bacterial SH3 domain; Region: SH3_3; pfam08239
1087448003663	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1087448003664	Peptidase family M23; Region: Peptidase_M23; pfam01551
1087448003665	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
1087448003666	nudix motif; other site
1087448003667	short chain dehydrogenase; Provisional; Region: PRK06701
1087448003668	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
1087448003669	NAD binding site [chemical binding]; other site
1087448003670	metal binding site [ion binding]; metal-binding site
1087448003671	active site
1087448003672	Predicted transcriptional regulators [Transcription]; Region: COG1725
1087448003673	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1087448003674	DNA-binding site [nucleotide binding]; DNA binding site
1087448003675	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1087448003676	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1087448003677	Walker A/P-loop; other site
1087448003678	ATP binding site [chemical binding]; other site
1087448003679	Q-loop/lid; other site
1087448003680	ABC transporter signature motif; other site
1087448003681	Walker B; other site
1087448003682	D-loop; other site
1087448003683	H-loop/switch region; other site
1087448003684	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1087448003685	NlpC/P60 family; Region: NLPC_P60; pfam00877
1087448003686	MFS transport protein AraJ; Provisional; Region: PRK10091
1087448003687	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1087448003688	putative substrate translocation pore; other site
1087448003689	Predicted redox protein, regulator of disulfide bond formation [Posttranslational modification, protein turnover, chaperones]; Region: COG1765
1087448003690	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1087448003691	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
1087448003692	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1087448003693	thiamine phosphate binding site [chemical binding]; other site
1087448003694	active site
1087448003695	pyrophosphate binding site [ion binding]; other site
1087448003696	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834
1087448003697	glycine oxidase ThiO; Region: thiamin_ThiO; TIGR02352
1087448003698	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1087448003699	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
1087448003700	thiS-thiF/thiG interaction site; other site
1087448003701	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
1087448003702	ThiS interaction site; other site
1087448003703	putative active site [active]
1087448003704	tetramer interface [polypeptide binding]; other site
1087448003705	hypothetical protein; Provisional; Region: PRK07758
1087448003706	DNA repair exonuclease [DNA replication, recombination, and repair]; Region: SbcD; COG0420
1087448003707	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
1087448003708	active site
1087448003709	metal binding site [ion binding]; metal-binding site
1087448003710	DNA binding site [nucleotide binding]
1087448003711	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
1087448003712	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419
1087448003713	ATP-binding cassette domain of sbcCD; Region: ABC_sbcCD; cd03279
1087448003714	Walker A/P-loop; other site
1087448003715	ATP binding site [chemical binding]; other site
1087448003716	Q-loop/lid; other site
1087448003717	ATP-binding cassette domain of sbcCD; Region: ABC_sbcCD; cd03279
1087448003718	ABC transporter signature motif; other site
1087448003719	Walker B; other site
1087448003720	D-loop; other site
1087448003721	H-loop/switch region; other site
1087448003722	Aminoglycoside 3-N-acetyltransferase; Region: Antibiotic_NAT; pfam02522
1087448003723	Bax inhibitor 1 like; Region: BaxI_1; cl17691
1087448003724	Predicted thiol-disulfide oxidoreductase [General function    prediction only]; Region: COG3011
1087448003725	Predicted transcriptional regulators [Transcription]; Region: COG1695
1087448003726	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1087448003727	hypothetical protein; Provisional; Region: PRK06771
1087448003728	Nuclease-related domain; Region: NERD; pfam08378
1087448003729	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1087448003730	MarR family; Region: MarR_2; pfam12802
1087448003731	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
1087448003732	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
1087448003733	YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062
1087448003734	atypical (a) SDRs, subgroup 5; Region: SDR_a5; cd05243
1087448003735	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1087448003736	NAD(P) binding site [chemical binding]; other site
1087448003737	putative active site [active]
1087448003738	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1087448003739	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1087448003740	substrate binding pocket [chemical binding]; other site
1087448003741	membrane-bound complex binding site; other site
1087448003742	hinge residues; other site
1087448003743	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1087448003744	daunorubicin resistance ABC transporter ATP-binding subunit; Region: drrA; TIGR01188
1087448003745	Walker A/P-loop; other site
1087448003746	ATP binding site [chemical binding]; other site
1087448003747	Q-loop/lid; other site
1087448003748	ABC transporter signature motif; other site
1087448003749	Walker B; other site
1087448003750	D-loop; other site
1087448003751	H-loop/switch region; other site
1087448003752	ABC-2 type transporter; Region: ABC2_membrane; cl17235
1087448003753	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1087448003754	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1087448003755	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1087448003756	Predicted permease [General function prediction only]; Region: COG2056
1087448003757	Na+-H+ antiporter family; Region: Na_H_antiport_2; pfam13726
1087448003758	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeD; cd03379
1087448003759	active site clefts [active]
1087448003760	zinc binding site [ion binding]; other site
1087448003761	dimer interface [polypeptide binding]; other site
1087448003762	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
1087448003763	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
1087448003764	putative catalytic cysteine [active]
1087448003765	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
1087448003766	putative active site [active]
1087448003767	metal binding site [ion binding]; metal-binding site
1087448003768	Phosphotransferase enzyme family; Region: APH; pfam01636
1087448003769	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1087448003770	active site
1087448003771	ATP binding site [chemical binding]; other site
1087448003772	substrate binding site [chemical binding]; other site
1087448003773	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
1087448003774	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
1087448003775	active site
1087448003776	metal binding site [ion binding]; metal-binding site
1087448003777	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1087448003778	Uncharacterized protein family (UPF0157); Region: UPF0157; pfam04229
1087448003779	DinB family; Region: DinB; cl17821
1087448003780	DinB superfamily; Region: DinB_2; pfam12867
1087448003781	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1087448003782	Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303
1087448003783	catalytic site [active]
1087448003784	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
1087448003785	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
1087448003786	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
1087448003787	cardiolipin synthetase; Reviewed; Region: PRK12452
1087448003788	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
1087448003789	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
1087448003790	putative active site [active]
1087448003791	catalytic site [active]
1087448003792	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
1087448003793	putative active site [active]
1087448003794	catalytic site [active]
1087448003795	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
1087448003796	This family represents an uncharacterized glycosyl hydrolase family 31 (GH31) enzyme found in bacteria and eukaryotes that is related to the XylS xylosidase of Sulfolobus solfataricus. Alpha-xylosidases catalyze the release of an alpha-xylose residue...; Region: GH31_xylosidase_XylS-like; cd06595
1087448003797	putative active site [active]
1087448003798	putative catalytic site [active]
1087448003799	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1087448003800	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1087448003801	catalytic residue [active]
1087448003802	Protein of unknown function (DUF2922); Region: DUF2922; pfam11148
1087448003803	Protein of unknown function (DUF1659); Region: DUF1659; pfam07872
1087448003804	Ion channel; Region: Ion_trans_2; pfam07885
1087448003805	TrkA-N domain; Region: TrkA_N; pfam02254
1087448003806	Peptidase S8 family domain in Subtilisin proteins; Region: Peptidases_S8_Subtilisin_subset; cd07477
1087448003807	active site
1087448003808	catalytic residues [active]
1087448003809	Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116
1087448003810	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
1087448003811	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1087448003812	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
1087448003813	Predicted Zn-dependent protease (DUF2268); Region: DUF2268; cl02316
1087448003814	cxxc_20_cxxc protein; Region: cxxc_20_cxxc; TIGR04104
1087448003815	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
1087448003816	catalytic residues [active]
1087448003817	dimer interface [polypeptide binding]; other site
1087448003818	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1087448003819	EamA-like transporter family; Region: EamA; pfam00892
1087448003820	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
1087448003821	Domain of unknown function (DUF4304); Region: DUF4304; pfam14137
1087448003822	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
1087448003823	Probable transposase; Region: OrfB_IS605; pfam01385
1087448003824	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
1087448003825	serine/threonine transporter SstT; Provisional; Region: PRK13628
1087448003826	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1087448003827	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
1087448003828	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1087448003829	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1087448003830	putative substrate translocation pore; other site
1087448003831	Predicted transcriptional regulators [Transcription]; Region: COG1733
1087448003832	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1087448003833	dimerization interface [polypeptide binding]; other site
1087448003834	putative DNA binding site [nucleotide binding]; other site
1087448003835	putative Zn2+ binding site [ion binding]; other site
1087448003836	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1087448003837	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_16; cd07263
1087448003838	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1087448003839	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1087448003840	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
1087448003841	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
1087448003842	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
1087448003843	putative active site [active]
1087448003844	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
1087448003845	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1087448003846	active site turn [active]
1087448003847	phosphorylation site [posttranslational modification]
1087448003848	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1087448003849	Uncharacterized conserved protein [Function unknown]; Region: COG3589
1087448003850	Bacterial protein of unknown function (DUF871); Region: DUF871; pfam05913
1087448003851	topology modulation protein; Reviewed; Region: PRK08118
1087448003852	AAA domain; Region: AAA_17; pfam13207
1087448003853	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1087448003854	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1087448003855	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
1087448003856	active site
1087448003857	Protein of unknown function (DUF1349); Region: DUF1349; pfam07081
1087448003858	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1087448003859	The substrate-binding component of an ABC-type nickel import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA; cd08489
1087448003860	substrate binding site [chemical binding]; other site
1087448003861	nickel ABC transporter, permease subunit NikB; Region: nickel_nikB; TIGR02789
1087448003862	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1087448003863	dimer interface [polypeptide binding]; other site
1087448003864	conserved gate region; other site
1087448003865	putative PBP binding loops; other site
1087448003866	ABC-ATPase subunit interface; other site
1087448003867	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
1087448003868	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1087448003869	dimer interface [polypeptide binding]; other site
1087448003870	conserved gate region; other site
1087448003871	putative PBP binding loops; other site
1087448003872	ABC-ATPase subunit interface; other site
1087448003873	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1087448003874	non-specific DNA binding site [nucleotide binding]; other site
1087448003875	salt bridge; other site
1087448003876	sequence-specific DNA binding site [nucleotide binding]; other site
1087448003877	Protein of unknown function (DUF3796); Region: DUF3796; pfam12676
1087448003878	NHL repeat; Region: NHL; pfam01436
1087448003879	Predicted membrane protein (DUF2243); Region: DUF2243; pfam10002
1087448003880	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG); Region: Caa3_CtaG; pfam09678
1087448003881	DinB superfamily; Region: DinB_2; pfam12867
1087448003882	Protein of unknown function (DUF1569); Region: DUF1569; pfam07606
1087448003883	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1087448003884	H+ Antiporter protein; Region: 2A0121; TIGR00900
1087448003885	putative substrate translocation pore; other site
1087448003886	Domain of unknown function (DUF4177); Region: DUF4177; pfam13783
1087448003887	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1087448003888	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1087448003889	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1087448003890	metal binding site [ion binding]; metal-binding site
1087448003891	active site
1087448003892	I-site; other site
1087448003893	Rifampin ADP-ribosyl transferase; Region: Arr-ms; pfam12120
1087448003894	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1087448003895	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1087448003896	active site
1087448003897	phosphorylation site [posttranslational modification]
1087448003898	intermolecular recognition site; other site
1087448003899	dimerization interface [polypeptide binding]; other site
1087448003900	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1087448003901	DNA binding site [nucleotide binding]
1087448003902	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
1087448003903	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539
1087448003904	Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane]; Region: COG3409
1087448003905	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1087448003906	Phage lysis protein, holin; Region: Phage_holin; pfam04688
1087448003907	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1087448003908	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1087448003909	metal binding site [ion binding]; metal-binding site
1087448003910	active site
1087448003911	I-site; other site
1087448003912	Beta-eliminating lyase; Region: Beta_elim_lyase; pfam01212
1087448003913	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1087448003914	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1087448003915	catalytic residue [active]
1087448003916	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
1087448003917	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1087448003918	DNA binding residues [nucleotide binding]
1087448003919	putative dimer interface [polypeptide binding]; other site
1087448003920	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
1087448003921	classical (c) SDRs; Region: SDR_c; cd05233
1087448003922	NAD(P) binding site [chemical binding]; other site
1087448003923	active site
1087448003924	H+ Antiporter protein; Region: 2A0121; TIGR00900
1087448003925	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1087448003926	putative substrate translocation pore; other site
1087448003927	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
1087448003928	heme-binding site [chemical binding]; other site
1087448003929	Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport...; Region: FNR_like; cl06868
1087448003930	FAD binding pocket [chemical binding]; other site
1087448003931	conserved FAD binding motif [chemical binding]; other site
1087448003932	phosphate binding motif [ion binding]; other site
1087448003933	beta-alpha-beta structure motif; other site
1087448003934	NAD binding pocket [chemical binding]; other site
1087448003935	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
1087448003936	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
1087448003937	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
1087448003938	RRXRR protein; Region: RRXRR; pfam14239
1087448003939	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1087448003940	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
1087448003941	active site
1087448003942	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1087448003943	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1087448003944	putative substrate translocation pore; other site
1087448003945	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1087448003946	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1087448003947	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1087448003948	DNA-binding site [nucleotide binding]; DNA binding site
1087448003949	FCD domain; Region: FCD; pfam07729
1087448003950	Multidrug resistance efflux transporter; Region: EmrE; pfam13536
1087448003951	Protein of unknown function (DUF554); Region: DUF554; pfam04474
1087448003952	MutT homolog-1 (MTH1) is a member of the Nudix hydrolase superfamily. MTH1, the mammalian counterpart of MutT, hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP and 2-hydroxy-ATP, to monophosphates, thereby preventing the...; Region: MTH1; cd03427
1087448003953	putative active site [active]
1087448003954	nucleotide binding site [chemical binding]; other site
1087448003955	nudix motif; other site
1087448003956	putative metal binding site [ion binding]; other site
1087448003957	N-acetyltransferase; Region: Acetyltransf_2; cl00949
1087448003958	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1087448003959	GAF domain; Region: GAF; pfam01590
1087448003960	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1087448003961	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1087448003962	metal binding site [ion binding]; metal-binding site
1087448003963	active site
1087448003964	I-site; other site
1087448003965	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_3; cd07241
1087448003966	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1087448003967	putative metal binding site [ion binding]; other site
1087448003968	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1087448003969	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1087448003970	putative substrate translocation pore; other site
1087448003971	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1087448003972	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1087448003973	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
1087448003974	active site pocket [active]
1087448003975	oxyanion hole [active]
1087448003976	catalytic triad [active]
1087448003977	active site nucleophile [active]
1087448003978	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4430
1087448003979	Bacteriocin-protection, YdeI or OmpD-Associated; Region: OmdA; pfam13376
1087448003980	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
1087448003981	nudix motif; other site
1087448003982	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
1087448003983	nudix motif; other site
1087448003984	hypothetical protein; Validated; Region: PRK06769
1087448003985	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1087448003986	active site
1087448003987	motif I; other site
1087448003988	motif II; other site
1087448003989	cardiolipin synthase; Region: bac_cardiolipin; TIGR04265
1087448003990	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
1087448003991	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
1087448003992	putative active site [active]
1087448003993	catalytic site [active]
1087448003994	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
1087448003995	putative active site [active]
1087448003996	catalytic site [active]
1087448003997	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1087448003998	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1087448003999	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1087448004000	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1087448004001	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1087448004002	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1087448004003	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1087448004004	Coenzyme A binding pocket [chemical binding]; other site
1087448004005	Choloylglycine hydrolase (CGH)_like. This family of choloylglycine hydrolase-like proteins includes conjugated bile acid hydrolase (CBAH), penicillin V acylase (PVA), acid ceramidase (AC), and N-acylethanolamine-hydrolyzing acid amidase (NAAA) which...; Region: Ntn_CGH_like; cd01935
1087448004006	active site
1087448004007	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase; Region: AAT; pfam03417
1087448004008	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1087448004009	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1087448004010	dimerization interface [polypeptide binding]; other site
1087448004011	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1087448004012	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1087448004013	dimer interface [polypeptide binding]; other site
1087448004014	putative CheW interface [polypeptide binding]; other site
1087448004015	Bacteriorhodopsin-like protein; Region: Bac_rhodopsin; smart01021
1087448004016	Bacteriorhodopsin-like protein; Region: Bac_rhodopsin; pfam01036
1087448004017	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1087448004018	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1087448004019	Coenzyme A binding pocket [chemical binding]; other site
1087448004020	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_7; cd08353
1087448004021	putative dimer interface [polypeptide binding]; other site
1087448004022	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1087448004023	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1087448004024	dimerization interface [polypeptide binding]; other site
1087448004025	putative DNA binding site [nucleotide binding]; other site
1087448004026	putative Zn2+ binding site [ion binding]; other site
1087448004027	arsenical pump membrane protein; Provisional; Region: PRK15445
1087448004028	Anion permease ArsB.  These permeases have been shown to export arsenate and antimonite in eubacteria and archaea.  A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118
1087448004029	transmembrane helices; other site
1087448004030	CoA-disulfide reductase; Region: CoA_CoA_reduc; TIGR03385
1087448004031	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1087448004032	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1087448004033	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1087448004034	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
1087448004035	active site residue [active]
1087448004036	YusW-like protein; Region: YusW; pfam14039
1087448004037	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1087448004038	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1087448004039	Coenzyme A binding pocket [chemical binding]; other site
1087448004040	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1087448004041	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1087448004042	non-specific DNA binding site [nucleotide binding]; other site
1087448004043	salt bridge; other site
1087448004044	sequence-specific DNA binding site [nucleotide binding]; other site
1087448004045	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1087448004046	Monoamine oxidase [Amino acid transport and metabolism]; Region: COG1231
1087448004047	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1087448004048	putative substrate translocation pore; other site
1087448004049	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1087448004050	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1087448004051	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1087448004052	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1087448004053	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1087448004054	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1087448004055	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1087448004056	DNA-binding site [nucleotide binding]; DNA binding site
1087448004057	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
1087448004058	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
1087448004059	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1087448004060	active site turn [active]
1087448004061	phosphorylation site [posttranslational modification]
1087448004062	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1087448004063	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1087448004064	HPr interaction site; other site
1087448004065	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1087448004066	active site
1087448004067	phosphorylation site [posttranslational modification]
1087448004068	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
1087448004069	beta-galactosidase; Region: BGL; TIGR03356
1087448004070	Phosphorylase superfamily; Region: PNP_UDP_1; pfam01048
1087448004071	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1087448004072	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1087448004073	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1087448004074	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1087448004075	Protein of unknown function (DUF3036); Region: DUF3036; pfam11234
1087448004076	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
1087448004077	SpoVT / AbrB like domain; Region: SpoVT_AbrB; smart00966
1087448004078	Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels [Inorganic ion transport and metabolism]; Region: COG0490
1087448004079	TrkA-C domain; Region: TrkA_C; pfam02080
1087448004080	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
1087448004081	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
1087448004082	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1087448004083	Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR1; cd08267
1087448004084	putative NAD(P) binding site [chemical binding]; other site
1087448004085	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1087448004086	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1087448004087	folate binding site [chemical binding]; other site
1087448004088	NADP+ binding site [chemical binding]; other site
1087448004089	Predicted transcriptional regulator [Transcription]; Region: COG2378
1087448004090	HTH domain; Region: HTH_11; pfam08279
1087448004091	WYL domain; Region: WYL; pfam13280
1087448004092	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
1087448004093	succinic semialdehyde dehydrogenase; Region: PLN02278
1087448004094	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
1087448004095	tetramerization interface [polypeptide binding]; other site
1087448004096	NAD(P) binding site [chemical binding]; other site
1087448004097	catalytic residues [active]
1087448004098	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1087448004099	tropinone reductase; Provisional; Region: PRK09242
1087448004100	NAD(P) binding site [chemical binding]; other site
1087448004101	active site
1087448004102	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1087448004103	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1087448004104	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1087448004105	dimerization interface [polypeptide binding]; other site
1087448004106	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1087448004107	dimerization interface [polypeptide binding]; other site
1087448004108	putative DNA binding site [nucleotide binding]; other site
1087448004109	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1087448004110	putative Zn2+ binding site [ion binding]; other site
1087448004111	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
1087448004112	hydrophobic ligand binding site; other site
1087448004113	Globin domain present in Globin-Coupled-Sensors (GCS). These domains detect changes in intracellular concentrations of oxygen, carbon monoxyde, or nitrous oxide,  which result in aerotaxis and/or gene regulation. One subgroup, the HemATs, are aerotactic...; Region: sensor_globin; cd01068
1087448004114	heme-binding site [chemical binding]; other site
1087448004115	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1087448004116	dimer interface [polypeptide binding]; other site
1087448004117	putative CheW interface [polypeptide binding]; other site
1087448004118	Domain of unknown function (DUF4362); Region: DUF4362; pfam14275
1087448004119	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1087448004120	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1087448004121	putative DNA binding site [nucleotide binding]; other site
1087448004122	putative Zn2+ binding site [ion binding]; other site
1087448004123	hypothetical protein; Provisional; Region: PRK09272
1087448004124	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1087448004125	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1087448004126	NAD(P) binding site [chemical binding]; other site
1087448004127	active site
1087448004128	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1087448004129	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1087448004130	putative substrate translocation pore; other site
1087448004131	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1087448004132	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1087448004133	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1087448004134	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1087448004135	Coenzyme A binding pocket [chemical binding]; other site
1087448004136	YCII-related domain; Region: YCII; cl00999
1087448004137	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1087448004138	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1087448004139	Walker A/P-loop; other site
1087448004140	ATP binding site [chemical binding]; other site
1087448004141	Q-loop/lid; other site
1087448004142	ABC transporter signature motif; other site
1087448004143	Walker B; other site
1087448004144	D-loop; other site
1087448004145	H-loop/switch region; other site
1087448004146	Uncharacterized protein family (UPF0014); Region: UPF0014; cl00424
1087448004147	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1087448004148	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1087448004149	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1087448004150	Bacterial protein of unknown function (DUF925); Region: DUF925; pfam06042
1087448004151	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1087448004152	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
1087448004153	active site
1087448004154	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1087448004155	dimerization interface [polypeptide binding]; other site
1087448004156	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1087448004157	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1087448004158	dimer interface [polypeptide binding]; other site
1087448004159	putative CheW interface [polypeptide binding]; other site
1087448004160	Protein of unknown function (DUF1572); Region: DUF1572; pfam07609
1087448004161	DinB superfamily; Region: DinB_2; pfam12867
1087448004162	Protein of unknown function (DUF1565); Region: DUF1565; pfam07602
1087448004163	Right handed beta helix region; Region: Beta_helix; pfam13229
1087448004164	parallel beta-helix repeat (two copies); Region: para_beta_helix; TIGR03804
1087448004165	PspC domain; Region: PspC; pfam04024
1087448004166	RecR protein; Region: RecR; pfam02132
1087448004167	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1087448004168	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
1087448004169	active site
1087448004170	metal binding site [ion binding]; metal-binding site
1087448004171	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1087448004172	PAS domain S-box; Region: sensory_box; TIGR00229
1087448004173	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1087448004174	putative active site [active]
1087448004175	heme pocket [chemical binding]; other site
1087448004176	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1087448004177	dimer interface [polypeptide binding]; other site
1087448004178	putative CheW interface [polypeptide binding]; other site
1087448004179	Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins; Region: SRPBCC_CalC_Aha1-like_4; cd08897
1087448004180	putative hydrophobic ligand binding site [chemical binding]; other site
1087448004181	Predicted transcriptional regulators [Transcription]; Region: COG1695
1087448004182	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1087448004183	Virulence activator alpha C-term; Region: Vir_act_alpha_C; pfam10400
1087448004184	Domain of unknown function (DUF4188); Region: DUF4188; pfam13826
1087448004185	helix_turn_helix ASNC type; Region: HTH_ASNC; smart00344
1087448004186	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1087448004187	putative DNA binding site [nucleotide binding]; other site
1087448004188	putative Zn2+ binding site [ion binding]; other site
1087448004189	AsnC family; Region: AsnC_trans_reg; pfam01037
1087448004190	Uncharacterized protein conserved in bacteria (DUF2200); Region: DUF2200; pfam09966
1087448004191	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1087448004192	alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases; Region: MDR_like_2; cd05289
1087448004193	putative NAD(P) binding site [chemical binding]; other site
1087448004194	Phosphotransferase enzyme family; Region: APH; pfam01636
1087448004195	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1087448004196	active site
1087448004197	ATP binding site [chemical binding]; other site
1087448004198	Uncharacterized conserved protein [Function unknown]; Region: COG3339
1087448004199	AAA domain; Region: AAA_17; cl17253
1087448004200	Ion channel; Region: Ion_trans_2; pfam07885
1087448004201	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
1087448004202	Cl- selectivity filter; other site
1087448004203	Cl- binding residues [ion binding]; other site
1087448004204	pore gating glutamate residue; other site
1087448004205	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1087448004206	Beta-lactamase; Region: Beta-lactamase; pfam00144
1087448004207	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1087448004208	catalytic residues [active]
1087448004209	catalytic nucleophile [active]
1087448004210	Presynaptic Site I dimer interface [polypeptide binding]; other site
1087448004211	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1087448004212	Synaptic Flat tetramer interface [polypeptide binding]; other site
1087448004213	Synaptic Site I dimer interface [polypeptide binding]; other site
1087448004214	biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; Region: BVR-B_like_SDR_a; cd05244
1087448004215	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1087448004216	NAD binding site [chemical binding]; other site
1087448004217	substrate binding site [chemical binding]; other site
1087448004218	putative active site [active]
1087448004219	Predicted transcriptional regulator [Transcription]; Region: COG1959
1087448004220	Transcriptional regulator; Region: Rrf2; pfam02082
1087448004221	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1087448004222	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1087448004223	Walker A/P-loop; other site
1087448004224	ATP binding site [chemical binding]; other site
1087448004225	Q-loop/lid; other site
1087448004226	ABC transporter signature motif; other site
1087448004227	Walker B; other site
1087448004228	D-loop; other site
1087448004229	H-loop/switch region; other site
1087448004230	luciferase family oxidoreductase, group 1; Region: oxido_grp_1; TIGR03558
1087448004231	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1087448004232	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
1087448004233	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
1087448004234	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1087448004235	NAD(P) binding site [chemical binding]; other site
1087448004236	active site
1087448004237	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
1087448004238	active site
1087448004239	NTP binding site [chemical binding]; other site
1087448004240	metal binding triad [ion binding]; metal-binding site
1087448004241	antibiotic binding site [chemical binding]; other site
1087448004242	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1087448004243	Coenzyme A binding pocket [chemical binding]; other site
1087448004244	Antibiotic biosynthesis monooxygenase; Region: ABM; cl10022
1087448004245	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1087448004246	Alpha/beta hydrolase of unknown function (DUF1057); Region: DUF1057; pfam06342
1087448004247	pyridine nucleotide-disulfide oxidoreductase family protein; Region: Nterm_to_SelD; TIGR03169
1087448004248	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1087448004249	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
1087448004250	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1087448004251	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1087448004252	Walker A/P-loop; other site
1087448004253	ATP binding site [chemical binding]; other site
1087448004254	Q-loop/lid; other site
1087448004255	ABC transporter signature motif; other site
1087448004256	Walker B; other site
1087448004257	D-loop; other site
1087448004258	H-loop/switch region; other site
1087448004259	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1087448004260	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1087448004261	Walker A/P-loop; other site
1087448004262	ATP binding site [chemical binding]; other site
1087448004263	Q-loop/lid; other site
1087448004264	ABC transporter signature motif; other site
1087448004265	Walker B; other site
1087448004266	D-loop; other site
1087448004267	H-loop/switch region; other site
1087448004268	ABC-type cobalt transport system, permease component; Region: ABC_cobalt; pfam09819
1087448004269	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
1087448004270	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1087448004271	5S rRNA interface [nucleotide binding]; other site
1087448004272	CTC domain interface [polypeptide binding]; other site
1087448004273	L16 interface [polypeptide binding]; other site
1087448004274	SWIM zinc finger; Region: SWIM; pfam04434
1087448004275	Bacterial SNF2 helicase associated; Region: SNF2_assoc; pfam08455
1087448004276	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
1087448004277	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1087448004278	ATP binding site [chemical binding]; other site
1087448004279	putative Mg++ binding site [ion binding]; other site
1087448004280	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1087448004281	nucleotide binding region [chemical binding]; other site
1087448004282	ATP-binding site [chemical binding]; other site
1087448004283	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
1087448004284	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1087448004285	active site
1087448004286	DNA binding site [nucleotide binding]
1087448004287	Int/Topo IB signature motif; other site
1087448004288	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
1087448004289	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
1087448004290	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1087448004291	ATP binding site [chemical binding]; other site
1087448004292	Mg2+ binding site [ion binding]; other site
1087448004293	G-X-G motif; other site
1087448004294	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1087448004295	anchoring element; other site
1087448004296	dimer interface [polypeptide binding]; other site
1087448004297	ATP binding site [chemical binding]; other site
1087448004298	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1087448004299	active site
1087448004300	putative metal-binding site [ion binding]; other site
1087448004301	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1087448004302	DNA topoisomerase IV, A subunit, Gram-positive; Region: parC_Gpos; TIGR01061
1087448004303	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1087448004304	CAP-like domain; other site
1087448004305	active site
1087448004306	primary dimer interface [polypeptide binding]; other site
1087448004307	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1087448004308	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1087448004309	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
1087448004310	nudix motif; other site
1087448004311	Protein of unknown function (DUF3307); Region: DUF3307; pfam11750
1087448004312	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1087448004313	catalytic core [active]
1087448004314	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
1087448004315	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1087448004316	MoxR-like ATPases [General function prediction only]; Region: COG0714
1087448004317	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1087448004318	Walker A motif; other site
1087448004319	ATP binding site [chemical binding]; other site
1087448004320	Walker B motif; other site
1087448004321	arginine finger; other site
1087448004322	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
1087448004323	Protein of unknown function DUF58; Region: DUF58; pfam01882
1087448004324	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1087448004325	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
1087448004326	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1087448004327	WYL domain; Region: WYL; pfam13280
1087448004328	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1087448004329	Heat induced stress protein YflT; Region: YflT; pfam11181
1087448004330	High-affinity Fe2+/Pb2+ permease [Inorganic ion transport and metabolism]; Region: FTR1; COG0672
1087448004331	Tat-translocated enzyme; Region: tat_substr_1; TIGR01412
1087448004332	Predicted iron-dependent peroxidase [Inorganic ion transport and metabolism]; Region: COG2837
1087448004333	Imelysin; Region: Peptidase_M75; pfam09375
1087448004334	Predicted membrane protein (DUF2339); Region: DUF2339; pfam10101
1087448004335	Bacterial SH3 domain; Region: SH3_3; pfam08239
1087448004336	Bacterial SH3 domain; Region: SH3_3; pfam08239
1087448004337	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
1087448004338	putative active site [active]
1087448004339	putative oxidoreductase; Provisional; Region: PRK10206
1087448004340	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1087448004341	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1087448004342	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1087448004343	Coenzyme A binding pocket [chemical binding]; other site
1087448004344	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
1087448004345	retinol dehydrogenase (retinol-DH), Light dependent Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and related proteins, classical (c) SDRs; Region: retinol-DH_like_SDR_c_like; cd05327
1087448004346	putative NAD(P) binding site [chemical binding]; other site
1087448004347	active site
1087448004348	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1087448004349	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
1087448004350	TrkA-C domain; Region: TrkA_C; pfam02080
1087448004351	Protein phosphatase 2C; Region: PP2C_2; pfam13672
1087448004352	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1087448004353	Predicted membrane protein [Function unknown]; Region: COG3428
1087448004354	Bacterial PH domain; Region: DUF304; pfam03703
1087448004355	Bacterial PH domain; Region: DUF304; pfam03703
1087448004356	Uncharacterized conserved protein [Function unknown]; Region: COG3402
1087448004357	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1087448004358	MarR family; Region: MarR; pfam01047
1087448004359	peroxiredoxin, Ohr subfamily; Region: organ_hyd_perox; TIGR03561
1087448004360	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1087448004361	synthetase active site [active]
1087448004362	NTP binding site [chemical binding]; other site
1087448004363	metal binding site [ion binding]; metal-binding site
1087448004364	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1087448004365	MarR family; Region: MarR; pfam01047
1087448004366	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1087448004367	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1087448004368	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1087448004369	binding surface
1087448004370	TPR motif; other site
1087448004371	Tetratrico peptide repeat; Region: TPR_5; pfam12688
1087448004372	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1087448004373	binding surface
1087448004374	TPR motif; other site
1087448004375	Phosphotransferase enzyme family; Region: APH; pfam01636
1087448004376	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1087448004377	active site
1087448004378	ATP binding site [chemical binding]; other site
1087448004379	substrate binding site [chemical binding]; other site
1087448004380	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1087448004381	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1087448004382	catalytic site [active]
1087448004383	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
1087448004384	Glycerophosphodiester phosphodiesterase domain of Thermoanaerobacter tengcongensis and similar proteins; Region: GDPD_TtGDE_like; cd08563
1087448004385	active site
1087448004386	catalytic site [active]
1087448004387	metal binding site [ion binding]; metal-binding site
1087448004388	dimer interface [polypeptide binding]; other site
1087448004389	Zn-dependent carboxypeptidase [Amino acid transport and metabolism]; Region: COG2317
1087448004390	Peptidase family M32 includes thermostable carboxypeptidases TaqCP and PfuCP; Region: M32_Taq; cd06460
1087448004391	active site
1087448004392	Zn binding site [ion binding]; other site
1087448004393	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1087448004394	active site
1087448004395	substrate binding site [chemical binding]; other site
1087448004396	ATP binding site [chemical binding]; other site
1087448004397	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
1087448004398	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
1087448004399	Probable transposase; Region: OrfB_IS605; pfam01385
1087448004400	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
1087448004401	Pleckstrin homology (PH)-like domains in bacteria (PHb); Region: PH-like_bacteria; cd13225
1087448004402	pentamer interface [polypeptide binding]; other site
1087448004403	dodecaamer interface [polypeptide binding]; other site
1087448004404	YCII-related domain; Region: YCII; cl00999
1087448004405	Creatinine amidohydrolase; Region: Creatininase; pfam02633
1087448004406	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1087448004407	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1087448004408	S-adenosylmethionine binding site [chemical binding]; other site
1087448004409	Protein of unknown function (DUF402); Region: DUF402; cl00979
1087448004410	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: PRK12748
1087448004411	classical (c) SDRs; Region: SDR_c; cd05233
1087448004412	NAD(P) binding site [chemical binding]; other site
1087448004413	active site
1087448004414	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_18; cd04677
1087448004415	nudix motif; other site
1087448004416	Uncharacterized conserved protein [Function unknown]; Region: COG4925
1087448004417	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
1087448004418	active site
1087448004419	substrate binding site [chemical binding]; other site
1087448004420	trimer interface [polypeptide binding]; other site
1087448004421	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
1087448004422	CoA binding site [chemical binding]; other site
1087448004423	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1087448004424	Coenzyme A binding pocket [chemical binding]; other site
1087448004425	RDD family; Region: RDD; pfam06271
1087448004426	Coenzyme F390 synthetase [Coenzyme metabolism]; Region: PaaK; COG1541
1087448004427	putative adenylate-forming enzyme; Region: aden_form_hyp; TIGR02304
1087448004428	putative adenylate-forming enzyme; Region: aden_form_hyp; TIGR02304
1087448004429	Coenzyme F390 synthetase [Coenzyme metabolism]; Region: PaaK; COG1541
1087448004430	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1087448004431	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1087448004432	NAD(P) binding site [chemical binding]; other site
1087448004433	active site
1087448004434	Dynamin-like protein including dynamins, mitofusins, and guanylate-binding proteins; Region: DLP_2; cd09912
1087448004435	Dynamin family; Region: Dynamin_N; pfam00350
1087448004436	G1 box; other site
1087448004437	GTP/Mg2+ binding site [chemical binding]; other site
1087448004438	G2 box; other site
1087448004439	Switch I region; other site
1087448004440	G3 box; other site
1087448004441	Switch II region; other site
1087448004442	G4 box; other site
1087448004443	G5 box; other site
1087448004444	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1087448004445	Dynamin family; Region: Dynamin_N; pfam00350
1087448004446	G1 box; other site
1087448004447	GTP/Mg2+ binding site [chemical binding]; other site
1087448004448	G2 box; other site
1087448004449	Switch I region; other site
1087448004450	Dynamin-like protein including dynamins, mitofusins, and guanylate-binding proteins; Region: DLP_2; cd09912
1087448004451	G3 box; other site
1087448004452	Switch II region; other site
1087448004453	G4 box; other site
1087448004454	G5 box; other site
1087448004455	Uncharacterized bacterial subfamily of the Thermotoga maritima CorA-like family; Region: TmCorA-like_u2; cd12831
1087448004456	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
1087448004457	oligomer interface [polypeptide binding]; other site
1087448004458	metal binding site [ion binding]; metal-binding site
1087448004459	metal binding site [ion binding]; metal-binding site
1087448004460	putative Cl binding site [ion binding]; other site
1087448004461	aspartate ring; other site
1087448004462	basic sphincter; other site
1087448004463	hydrophobic gate; other site
1087448004464	periplasmic entrance; other site
1087448004465	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1087448004466	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1087448004467	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
1087448004468	The tRNA binding domain is also known as the Myf domain in literature. This domain is found in a diverse collection of tRNA binding proteins, including prokaryotic phenylalanyl tRNA synthetases (PheRS), methionyl-tRNA synthetases (MetRS), human...; Region: tRNA_bindingDomain; cl00320
1087448004469	putative tRNA-binding site [nucleotide binding]; other site
1087448004470	ergothioneine biosynthesis protein EgtB; Region: egtB_TIGR03440
1087448004471	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
1087448004472	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05458
1087448004473	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1087448004474	active site
1087448004475	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
1087448004476	nudix motif; other site
1087448004477	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1087448004478	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1087448004479	RNA polymerase sigma factor; Provisional; Region: PRK12515
1087448004480	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1087448004481	DNA-binding site [nucleotide binding]; DNA binding site
1087448004482	RNA-binding motif; other site
1087448004483	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1087448004484	DNA-binding site [nucleotide binding]; DNA binding site
1087448004485	RNA-binding motif; other site
1087448004486	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1087448004487	DNA-binding site [nucleotide binding]; DNA binding site
1087448004488	RNA-binding motif; other site
1087448004489	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1087448004490	DNA-binding site [nucleotide binding]; DNA binding site
1087448004491	RNA-binding motif; other site
1087448004492	Putative D-3-Phosphoglycerate Dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_like_3; cd12174
1087448004493	glycerate dehydrogenase; Provisional; Region: PRK06436
1087448004494	putative ligand binding site [chemical binding]; other site
1087448004495	putative NAD binding site [chemical binding]; other site
1087448004496	putative catalytic site [active]
1087448004497	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
1087448004498	L-serine binding site [chemical binding]; other site
1087448004499	ACT domain interface; other site
1087448004500	Protein of unknown function (DUF1015); Region: DUF1015; pfam06245
1087448004501	Uncharacterized conserved protein [Function unknown]; Region: COG4198
1087448004502	maltodextrin glucosidase; Provisional; Region: PRK10785
1087448004503	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
1087448004504	homodimer interface [polypeptide binding]; other site
1087448004505	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
1087448004506	active site
1087448004507	homodimer interface [polypeptide binding]; other site
1087448004508	catalytic site [active]
1087448004509	Beta-galactosidase C-terminal domain; Region: Glyco_hydro_42C; pfam08533
1087448004510	hypothetical protein; Provisional; Region: PRK12378
1087448004511	monovalent cation/H+ antiporter subunit A; Reviewed; Region: PRK12645
1087448004512	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1087448004513	Multisubunit Na+/H+ antiporter, MnhB subunit [Inorganic ion transport and metabolism]; Region: MnhB; COG2111
1087448004514	putative monovalent cation/H+ antiporter subunit B; Reviewed; Region: PRK12573
1087448004515	putative monovalent cation/H+ antiporter subunit C; Reviewed; Region: PRK08600
1087448004516	putative monovalent cation/H+ antiporter subunit D; Reviewed; Region: PRK07691
1087448004517	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1087448004518	putative monovalent cation/H+ antiporter subunit E; Reviewed; Region: PRK12651
1087448004519	putative monovalent cation/H+ antiporter subunit F; Reviewed; Region: PRK12600
1087448004520	putative monovalent cation/H+ antiporter subunit G; Reviewed; Region: PRK12586
1087448004521	Transcriptional regulator; Region: Rrf2; cl17282
1087448004522	Predicted transcriptional regulator [Transcription]; Region: COG1959
1087448004523	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
1087448004524	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1087448004525	E3 interaction surface; other site
1087448004526	lipoyl attachment site [posttranslational modification]; other site
1087448004527	e3 binding domain; Region: E3_binding; pfam02817
1087448004528	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1087448004529	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
1087448004530	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
1087448004531	TPP-binding site [chemical binding]; other site
1087448004532	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
1087448004533	dimer interface [polypeptide binding]; other site
1087448004534	PYR/PP interface [polypeptide binding]; other site
1087448004535	TPP binding site [chemical binding]; other site
1087448004536	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1087448004537	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1087448004538	Walker A/P-loop; other site
1087448004539	ATP binding site [chemical binding]; other site
1087448004540	Q-loop/lid; other site
1087448004541	ABC transporter signature motif; other site
1087448004542	Walker B; other site
1087448004543	D-loop; other site
1087448004544	H-loop/switch region; other site
1087448004545	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1087448004546	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1087448004547	dimer interface [polypeptide binding]; other site
1087448004548	conserved gate region; other site
1087448004549	putative PBP binding loops; other site
1087448004550	ABC-ATPase subunit interface; other site
1087448004551	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1087448004552	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1087448004553	substrate binding pocket [chemical binding]; other site
1087448004554	membrane-bound complex binding site; other site
1087448004555	hinge residues; other site
1087448004556	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1087448004557	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1087448004558	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1087448004559	Microcin C7 self-immunity protein determines resistance to exogenous microcin C7; Region: Peptidase_S66_mccF_like; cd07062
1087448004560	putative dimer interface [polypeptide binding]; other site
1087448004561	catalytic triad [active]
1087448004562	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1087448004563	catalytic residues [active]
1087448004564	Protein of unknown function (DUF779); Region: DUF779; pfam05610
1087448004565	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like; Region: ALDH_ACDHII-AcoD; cd07116
1087448004566	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1087448004567	NAD(P) binding site [chemical binding]; other site
1087448004568	catalytic residues [active]
1087448004569	Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; cl00755
1087448004570	glutamate synthase subunit beta; Reviewed; Region: gltD; PRK12810
1087448004571	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1087448004572	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
1087448004573	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
1087448004574	active site
1087448004575	dimer interface [polypeptide binding]; other site
1087448004576	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
1087448004577	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
1087448004578	active site
1087448004579	FMN binding site [chemical binding]; other site
1087448004580	substrate binding site [chemical binding]; other site
1087448004581	3Fe-4S cluster binding site [ion binding]; other site
1087448004582	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
1087448004583	domain interface; other site
1087448004584	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1087448004585	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1087448004586	substrate binding pocket [chemical binding]; other site
1087448004587	membrane-bound complex binding site; other site
1087448004588	hinge residues; other site
1087448004589	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1087448004590	dimer interface [polypeptide binding]; other site
1087448004591	conserved gate region; other site
1087448004592	putative PBP binding loops; other site
1087448004593	ABC-ATPase subunit interface; other site
1087448004594	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1087448004595	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1087448004596	metal binding site [ion binding]; metal-binding site
1087448004597	active site
1087448004598	I-site; other site
1087448004599	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1087448004600	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1087448004601	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1087448004602	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1087448004603	non-specific DNA binding site [nucleotide binding]; other site
1087448004604	salt bridge; other site
1087448004605	sequence-specific DNA binding site [nucleotide binding]; other site
1087448004606	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
1087448004607	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1087448004608	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1087448004609	homodimer interface [polypeptide binding]; other site
1087448004610	catalytic residue [active]
1087448004611	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1087448004612	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
1087448004613	Na binding site [ion binding]; other site
1087448004614	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1087448004615	Uncharacterized member of the PurR regulon [General function prediction only]; Region: yhhQ; COG1738
1087448004616	PilZ domain; Region: PilZ; pfam07238
1087448004617	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
1087448004618	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1087448004619	Ca binding site [ion binding]; other site
1087448004620	active site
1087448004621	catalytic site [active]
1087448004622	thymidylate synthase; Reviewed; Region: thyA; PRK01827
1087448004623	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
1087448004624	dimerization interface [polypeptide binding]; other site
1087448004625	fumarate hydratase; Reviewed; Region: fumC; PRK00485
1087448004626	Class II fumarases; Region: Fumarase_classII; cd01362
1087448004627	active site
1087448004628	tetramer interface [polypeptide binding]; other site
1087448004629	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1087448004630	Domain of unknown function DUF21; Region: DUF21; pfam01595
1087448004631	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1087448004632	Transporter associated domain; Region: CorC_HlyC; smart01091
1087448004633	RNAse HI family that includes Archaeal RNase HI; Region: RNase_HI_archaeal_like; cd09279
1087448004634	RNA/DNA hybrid binding site [nucleotide binding]; other site
1087448004635	active site
1087448004636	3'-5' exoribonuclease YhaM; Provisional; Region: PRK13480
1087448004637	Cytidine and deoxycytidylate deaminase zinc-binding region. The family contains cytidine deaminases, nucleoside deaminases, deoxycytidylate deaminases and riboflavin deaminases. Also included are the apoBec family of mRNA editing enzymes.  All members...; Region: cytidine_deaminase-like; cl00269
1087448004638	active site
1087448004639	Zn binding site [ion binding]; other site
1087448004640	Toxic anion resistance protein (TelA); Region: TelA; pfam05816
1087448004641	5-bromo-4-chloroindolyl phosphate hydrolysis protein; Region: Halogen_Hydrol; cl02059
1087448004642	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
1087448004643	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
1087448004644	Probable transposase; Region: OrfB_IS605; pfam01385
1087448004645	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
1087448004646	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
1087448004647	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1087448004648	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1087448004649	dimer interface [polypeptide binding]; other site
1087448004650	conserved gate region; other site
1087448004651	ABC-ATPase subunit interface; other site
1087448004652	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
1087448004653	ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; cl17891
1087448004654	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1087448004655	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
1087448004656	Walker A/P-loop; other site
1087448004657	ATP binding site [chemical binding]; other site
1087448004658	Q-loop/lid; other site
1087448004659	ABC transporter signature motif; other site
1087448004660	Walker B; other site
1087448004661	D-loop; other site
1087448004662	H-loop/switch region; other site
1087448004663	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
1087448004664	putative active site [active]
1087448004665	putative CoA binding site [chemical binding]; other site
1087448004666	nudix motif; other site
1087448004667	metal binding site [ion binding]; metal-binding site
1087448004668	YvfG protein; Region: YvfG; pfam09628
1087448004669	hypothetical protein; Provisional; Region: PRK06184
1087448004670	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1087448004671	cell division protein GpsB; Provisional; Region: PRK14127
1087448004672	DivIVA domain; Region: DivI1A_domain; TIGR03544
1087448004673	hypothetical protein; Provisional; Region: PRK13660
1087448004674	RNase_H superfamily; Region: RNase_H_2; pfam13482
1087448004675	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1087448004676	binding surface
1087448004677	TPR motif; other site
1087448004678	Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster [General function prediction only]; Region: COG1205
1087448004679	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1087448004680	ATP binding site [chemical binding]; other site
1087448004681	putative Mg++ binding site [ion binding]; other site
1087448004682	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1087448004683	nucleotide binding region [chemical binding]; other site
1087448004684	ATP-binding site [chemical binding]; other site
1087448004685	Domain of unknown function (DUF1998); Region: DUF1998; pfam09369
1087448004686	Holliday junction-specific endonuclease; Reviewed; Region: recU; PRK02234
1087448004687	Bacterial domain of unknown function (DUF1798); Region: DUF1798; pfam08807
1087448004688	Protein of unknown function (DUF3800); Region: DUF3800; pfam12686
1087448004689	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
1087448004690	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1087448004691	minor groove reading motif; other site
1087448004692	helix-hairpin-helix signature motif; other site
1087448004693	substrate binding pocket [chemical binding]; other site
1087448004694	active site
1087448004695	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; cl15304
1087448004696	Putative primosome component and related proteins [DNA replication, recombination, and repair]; Region: DnaD; COG3935
1087448004697	Replication initiation and membrane attachment; Region: DnaB_2; cl12121
1087448004698	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
1087448004699	AsnRS_cyto_like_N: N-terminal, anticodon recognition domain of the type found in human and Saccharomyces cerevisiae cytoplasmic asparaginyl-tRNA synthetase (AsnRS), in Brugia malayai AsnRs and, in various putative bacterial AsnRSs.  This domain is a...; Region: AsnRS_cyto_like_N; cd04323
1087448004700	putative dimer interface [polypeptide binding]; other site
1087448004701	putative anticodon binding site; other site
1087448004702	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
1087448004703	homodimer interface [polypeptide binding]; other site
1087448004704	motif 1; other site
1087448004705	motif 2; other site
1087448004706	active site
1087448004707	motif 3; other site
1087448004708	aspartate aminotransferase; Provisional; Region: PRK05764
1087448004709	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1087448004710	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1087448004711	homodimer interface [polypeptide binding]; other site
1087448004712	catalytic residue [active]
1087448004713	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5353
1087448004714	Protein of unknown function (DUF4264); Region: DUF4264; pfam14084
1087448004715	bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated; Region: PRK08074
1087448004716	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1087448004717	active site
1087448004718	catalytic site [active]
1087448004719	substrate binding site [chemical binding]; other site
1087448004720	CRISPR/Cas system-associated DinG family helicase Csf4; Region: Csf4_U; cl17460
1087448004721	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
1087448004722	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
1087448004723	tetramerization interface [polypeptide binding]; other site
1087448004724	active site
1087448004725	pantoate--beta-alanine ligase; Region: panC; TIGR00018
1087448004726	Pantoate-beta-alanine ligase; Region: PanC; cd00560
1087448004727	active site
1087448004728	ATP-binding site [chemical binding]; other site
1087448004729	pantoate-binding site; other site
1087448004730	HXXH motif; other site
1087448004731	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
1087448004732	active site
1087448004733	oligomerization interface [polypeptide binding]; other site
1087448004734	metal binding site [ion binding]; metal-binding site
1087448004735	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
1087448004736	Biotin operon repressor [Transcription]; Region: BirA; COG1654
1087448004737	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
1087448004738	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
1087448004739	tRNA CCA-pyrophosphorylase; Provisional; Region: PRK13299
1087448004740	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1087448004741	active site
1087448004742	NTP binding site [chemical binding]; other site
1087448004743	metal binding triad [ion binding]; metal-binding site
1087448004744	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1087448004745	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
1087448004746	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_5; cd04962
1087448004747	N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA; Region: thiol_BshA; TIGR03999
1087448004748	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1087448004749	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1087448004750	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1087448004751	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1087448004752	Putative neutral zinc metallopeptidase; Region: Zn_peptidase_2; pfam04298
1087448004753	Protein of unknown function (DUF1405); Region: DUF1405; pfam07187
1087448004754	Cytochrome b(C-terminus)/b6/petD:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: cytochrome_b_C; cl00193
1087448004755	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
1087448004756	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
1087448004757	cytochrome b6; Provisional; Region: PRK03735
1087448004758	Cytochrome b subunit of the bc complex [Energy production and conversion]; Region: QcrB; COG1290
1087448004759	interchain domain interface [polypeptide binding]; other site
1087448004760	intrachain domain interface; other site
1087448004761	heme bH binding site [chemical binding]; other site
1087448004762	Qi binding site; other site
1087448004763	heme bL binding site [chemical binding]; other site
1087448004764	Qo binding site; other site
1087448004765	Rieske Fe-S protein [Energy production and conversion]; Region: QcrA; COG0723
1087448004766	Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal; Region: UCR_Fe-S_N; pfam10399
1087448004767	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cd03467
1087448004768	iron-sulfur cluster [ion binding]; other site
1087448004769	[2Fe-2S] cluster binding site [ion binding]; other site
1087448004770	Protein of unknown function (DUF2487); Region: DUF2487; pfam10673
1087448004771	hypothetical protein; Provisional; Region: PRK03636
1087448004772	UPF0302 domain; Region: UPF0302; pfam08864
1087448004773	IDEAL domain; Region: IDEAL; pfam08858
1087448004774	Anaphase-promoting complex, cyclosome, subunit 3; Region: Apc3; pfam12895
1087448004775	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1087448004776	binding surface
1087448004777	TPR motif; other site
1087448004778	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1087448004779	TPR motif; other site
1087448004780	binding surface
1087448004781	Anaphase-promoting complex, cyclosome, subunit 3; Region: Apc3; pfam12895
1087448004782	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1087448004783	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
1087448004784	active site
1087448004785	hinge; other site
1087448004786	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1087448004787	active site
1087448004788	dimer interface [polypeptide binding]; other site
1087448004789	metal binding site [ion binding]; metal-binding site
1087448004790	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
1087448004791	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1087448004792	Tetramer interface [polypeptide binding]; other site
1087448004793	active site
1087448004794	FMN-binding site [chemical binding]; other site
1087448004795	Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheR; COG1352
1087448004796	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
1087448004797	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1087448004798	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
1087448004799	active site
1087448004800	multimer interface [polypeptide binding]; other site
1087448004801	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1087448004802	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1087448004803	substrate binding pocket [chemical binding]; other site
1087448004804	chain length determination region; other site
1087448004805	substrate-Mg2+ binding site; other site
1087448004806	catalytic residues [active]
1087448004807	aspartate-rich region 1; other site
1087448004808	active site lid residues [active]
1087448004809	aspartate-rich region 2; other site
1087448004810	ubiE/COQ5 methyltransferase family; Region: Ubie_methyltran; pfam01209
1087448004811	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1087448004812	S-adenosylmethionine binding site [chemical binding]; other site
1087448004813	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1; Region: HEPPP_synt_1; pfam07307
1087448004814	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1087448004815	IHF dimer interface [polypeptide binding]; other site
1087448004816	IHF - DNA interface [nucleotide binding]; other site
1087448004817	Protein of unknown function (DUF2768); Region: DUF2768; pfam10966
1087448004818	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1087448004819	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1087448004820	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1087448004821	GTP-binding protein Der; Reviewed; Region: PRK00093
1087448004822	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1087448004823	G1 box; other site
1087448004824	GTP/Mg2+ binding site [chemical binding]; other site
1087448004825	Switch I region; other site
1087448004826	G2 box; other site
1087448004827	Switch II region; other site
1087448004828	G3 box; other site
1087448004829	G4 box; other site
1087448004830	G5 box; other site
1087448004831	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1087448004832	G1 box; other site
1087448004833	GTP/Mg2+ binding site [chemical binding]; other site
1087448004834	Switch I region; other site
1087448004835	G2 box; other site
1087448004836	G3 box; other site
1087448004837	Switch II region; other site
1087448004838	G4 box; other site
1087448004839	G5 box; other site
1087448004840	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06676
1087448004841	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
1087448004842	RNA binding site [nucleotide binding]; other site
1087448004843	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1087448004844	RNA binding site [nucleotide binding]; other site
1087448004845	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1087448004846	RNA binding site [nucleotide binding]; other site
1087448004847	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1087448004848	RNA binding site [nucleotide binding]; other site
1087448004849	domain interface; other site
1087448004850	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1087448004851	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1087448004852	putative acyl-acceptor binding pocket; other site
1087448004853	cytidylate kinase; Provisional; Region: cmk; PRK00023
1087448004854	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
1087448004855	CMP-binding site; other site
1087448004856	The sites determining sugar specificity; other site
1087448004857	Flagellar protein YcgR; Region: YcgR_2; pfam12945
1087448004858	PilZ domain; Region: PilZ; pfam07238
1087448004859	Protease prsW family; Region: PrsW-protease; pfam13367
1087448004860	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
1087448004861	active site
1087448004862	homotetramer interface [polypeptide binding]; other site
1087448004863	homodimer interface [polypeptide binding]; other site
1087448004864	putative bacillithiol system oxidoreductase, YpdA family; Region: Bthiol_YpdA; TIGR04018
1087448004865	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_3; pfam13738
1087448004866	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1087448004867	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
1087448004868	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1087448004869	NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076
1087448004870	NAD(P) binding site [chemical binding]; other site
1087448004871	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
1087448004872	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1087448004873	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1087448004874	Negative regulator of genetic competence (MecA); Region: MecA; cl02022
1087448004875	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
1087448004876	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1087448004877	DNA binding residues [nucleotide binding]
1087448004878	B12 binding domain; Region: B12-binding_2; pfam02607
1087448004879	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cd02065
1087448004880	B12 binding site [chemical binding]; other site
1087448004881	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1087448004882	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1087448004883	ATP binding site [chemical binding]; other site
1087448004884	putative Mg++ binding site [ion binding]; other site
1087448004885	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1087448004886	nucleotide binding region [chemical binding]; other site
1087448004887	ATP-binding site [chemical binding]; other site
1087448004888	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4955
1087448004889	Ferredoxin [Energy production and conversion]; Region: Fer; COG1141
1087448004890	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1087448004891	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
1087448004892	TM-ABC transporter signature motif; other site
1087448004893	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1087448004894	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
1087448004895	TM-ABC transporter signature motif; other site
1087448004896	ABC-type uncharacterized transport systems, ATPase components [General function prediction only]; Region: COG3845
1087448004897	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1087448004898	Walker A/P-loop; other site
1087448004899	ATP binding site [chemical binding]; other site
1087448004900	Q-loop/lid; other site
1087448004901	ABC transporter signature motif; other site
1087448004902	Walker B; other site
1087448004903	D-loop; other site
1087448004904	H-loop/switch region; other site
1087448004905	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1087448004906	Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only]; Region: Med; COG1744
1087448004907	Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea; Region: PBP1_BmpA_PnrA_like; cd06354
1087448004908	ligand binding site [chemical binding]; other site
1087448004909	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1087448004910	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1087448004911	DNA-binding site [nucleotide binding]; DNA binding site
1087448004912	UTRA domain; Region: UTRA; pfam07702
1087448004913	Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only]; Region: Med; COG1744
1087448004914	Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea; Region: PBP1_BmpA_PnrA_like; cd06354
1087448004915	ligand binding site [chemical binding]; other site
1087448004916	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
1087448004917	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1087448004918	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
1087448004919	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
1087448004920	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1087448004921	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
1087448004922	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539
1087448004923	FemAB family; Region: FemAB; pfam02388
1087448004924	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
1087448004925	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1087448004926	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1087448004927	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1087448004928	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1087448004929	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1087448004930	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1087448004931	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1087448004932	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1087448004933	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
1087448004934	RNase E interface [polypeptide binding]; other site
1087448004935	trimer interface [polypeptide binding]; other site
1087448004936	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1087448004937	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1087448004938	RNase E interface [polypeptide binding]; other site
1087448004939	trimer interface [polypeptide binding]; other site
1087448004940	active site
1087448004941	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1087448004942	putative nucleic acid binding region [nucleotide binding]; other site
1087448004943	G-X-X-G motif; other site
1087448004944	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1087448004945	RNA binding site [nucleotide binding]; other site
1087448004946	domain interface; other site
1087448004947	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1087448004948	16S/18S rRNA binding site [nucleotide binding]; other site
1087448004949	S13e-L30e interaction site [polypeptide binding]; other site
1087448004950	25S rRNA binding site [nucleotide binding]; other site
1087448004951	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
1087448004952	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1087448004953	active site
1087448004954	Riboflavin kinase; Region: Flavokinase; smart00904
1087448004955	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK01550
1087448004956	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1087448004957	RNA binding site [nucleotide binding]; other site
1087448004958	active site
1087448004959	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
1087448004960	translation initiation factor IF-2; Validated; Region: infB; PRK05306
1087448004961	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1087448004962	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1087448004963	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1087448004964	G1 box; other site
1087448004965	putative GEF interaction site [polypeptide binding]; other site
1087448004966	GTP/Mg2+ binding site [chemical binding]; other site
1087448004967	Switch I region; other site
1087448004968	G2 box; other site
1087448004969	G3 box; other site
1087448004970	Switch II region; other site
1087448004971	G4 box; other site
1087448004972	G5 box; other site
1087448004973	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1087448004974	Translation-initiation factor 2; Region: IF-2; pfam11987
1087448004975	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1087448004976	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; Region: Ribosomal_L7Ae; cl00600
1087448004977	Ylxr homologs; group of conserved hypothetical bacterial proteins of unknown function; structure revealed putative RNA binding cleft; proteins are encoded by an operon that includes other proteins involved in transcription and/or translation; Region: YlxR; cd00279
1087448004978	putative RNA binding cleft [nucleotide binding]; other site
1087448004979	transcription elongation factor NusA; Provisional; Region: nusA; PRK12327
1087448004980	NusA N-terminal domain; Region: NusA_N; pfam08529
1087448004981	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1087448004982	RNA binding site [nucleotide binding]; other site
1087448004983	homodimer interface [polypeptide binding]; other site
1087448004984	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1087448004985	G-X-X-G motif; other site
1087448004986	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1087448004987	G-X-X-G motif; other site
1087448004988	ribosome maturation protein RimP; Reviewed; Region: PRK00092
1087448004989	Sm and related proteins; Region: Sm_like; cl00259
1087448004990	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
1087448004991	putative oligomer interface [polypeptide binding]; other site
1087448004992	putative RNA binding site [nucleotide binding]; other site
1087448004993	DNA polymerase III PolC; Validated; Region: polC; PRK00448
1087448004994	DNA polymerase III polC-type N-terminus; Region: DNA_pol3_alph_N; pfam11490
1087448004995	polC_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold nucleic acid binding domain of Bacillus subtilis type C replicative DNA polymerase III alpha subunit (polC). Replication in B. subtilis and Staphylococcus aureus requires two...; Region: polC_OBF; cd04484
1087448004996	generic binding surface II; other site
1087448004997	generic binding surface I; other site
1087448004998	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
1087448004999	active site
1087448005000	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1087448005001	active site
1087448005002	catalytic site [active]
1087448005003	substrate binding site [chemical binding]; other site
1087448005004	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III at PolC gene; Region: PHP_PolIIIA_POLC; cd07435
1087448005005	prolyl-tRNA synthetase; Provisional; Region: PRK09194
1087448005006	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1087448005007	dimer interface [polypeptide binding]; other site
1087448005008	motif 1; other site
1087448005009	active site
1087448005010	motif 2; other site
1087448005011	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
1087448005012	putative deacylase active site [active]
1087448005013	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1087448005014	active site
1087448005015	motif 3; other site
1087448005016	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1087448005017	anticodon binding site; other site
1087448005018	RIP metalloprotease RseP; Region: TIGR00054
1087448005019	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1087448005020	active site
1087448005021	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
1087448005022	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1087448005023	protein binding site [polypeptide binding]; other site
1087448005024	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1087448005025	putative substrate binding region [chemical binding]; other site
1087448005026	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
1087448005027	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
1087448005028	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
1087448005029	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
1087448005030	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1087448005031	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
1087448005032	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
1087448005033	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
1087448005034	catalytic residue [active]
1087448005035	putative FPP diphosphate  binding site; other site
1087448005036	putative FPP binding hydrophobic cleft; other site
1087448005037	dimer interface [polypeptide binding]; other site
1087448005038	putative IPP diphosphate binding site; other site
1087448005039	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1087448005040	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1087448005041	hinge region; other site
1087448005042	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1087448005043	putative nucleotide binding site [chemical binding]; other site
1087448005044	uridine monophosphate binding site [chemical binding]; other site
1087448005045	homohexameric interface [polypeptide binding]; other site
1087448005046	elongation factor Ts; Provisional; Region: tsf; PRK09377
1087448005047	UBA/TS-N domain; Region: UBA; pfam00627
1087448005048	Elongation factor TS; Region: EF_TS; pfam00889
1087448005049	Elongation factor TS; Region: EF_TS; pfam00889
1087448005050	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1087448005051	rRNA interaction site [nucleotide binding]; other site
1087448005052	S8 interaction site; other site
1087448005053	putative laminin-1 binding site; other site
1087448005054	RNA polymerase sigma factor SigD; Validated; Region: PRK07670
1087448005055	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1087448005056	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1087448005057	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1087448005058	DNA binding residues [nucleotide binding]
1087448005059	CheD chemotactic sensory transduction; Region: CheD; cl00810
1087448005060	Chemotaxis protein CheC, inhibitor of MCP methylation [Cell motility and secretion / Signal transduction mechanisms]; Region: CheC; COG1776
1087448005061	Chemotaxis phosphatase CheX; Region: CheX; cl15816
1087448005062	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
1087448005063	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
1087448005064	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1087448005065	putative binding surface; other site
1087448005066	active site
1087448005067	P2 response regulator binding domain; Region: P2; pfam07194
1087448005068	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
1087448005069	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1087448005070	ATP binding site [chemical binding]; other site
1087448005071	Mg2+ binding site [ion binding]; other site
1087448005072	G-X-G motif; other site
1087448005073	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
1087448005074	Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]; Region: flhG; COG0455
1087448005075	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
1087448005076	P-loop; other site
1087448005077	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
1087448005078	Flagellar GTP-binding protein [Cell motility and secretion]; Region: FlhF; COG1419
1087448005079	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1087448005080	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
1087448005081	FHIPEP family; Region: FHIPEP; pfam00771
1087448005082	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
1087448005083	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
1087448005084	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
1087448005085	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
1087448005086	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
1087448005087	Response regulator receiver domain; Region: Response_reg; pfam00072
1087448005088	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1087448005089	active site
1087448005090	phosphorylation site [posttranslational modification]
1087448005091	intermolecular recognition site; other site
1087448005092	dimerization interface [polypeptide binding]; other site
1087448005093	flagellar motor switch protein; Validated; Region: PRK08119
1087448005094	CheC-like family; Region: CheC; pfam04509
1087448005095	CheC-like family; Region: CheC; pfam04509
1087448005096	Ribosome biogenesis regulatory protein (RRS1); Region: RRS1; cl02166
1087448005097	flagellar motor switch protein FliN; Region: fliN; TIGR02480
1087448005098	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
1087448005099	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
1087448005100	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07718
1087448005101	Flagellar basal body-associated protein FliL; Region: FliL; pfam03748
1087448005102	Flagellar protein (FlbD); Region: FlbD; pfam06289
1087448005103	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12636
1087448005104	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1087448005105	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1087448005106	flagellar basal body rod modification protein; Provisional; Region: flgD; PRK09618
1087448005107	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
1087448005108	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
1087448005109	Uncharacterized conserved protein [Function unknown]; Region: COG3334
1087448005110	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK07720
1087448005111	flagellar export protein FliJ; Region: flagell_FliJ; TIGR02473
1087448005112	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07721
1087448005113	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1087448005114	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
1087448005115	Walker A motif/ATP binding site; other site
1087448005116	Walker B motif; other site
1087448005117	flagellar assembly protein FliH; Region: FliH_bacil; TIGR03825
1087448005118	Flagellar assembly protein FliH; Region: FliH; pfam02108
1087448005119	flagellar motor switch protein G; Validated; Region: fliG; PRK05686
1087448005120	FliG C-terminal domain; Region: FliG_C; pfam01706
1087448005121	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
1087448005122	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907
1087448005123	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
1087448005124	Flagellar hook-basal body complex protein FliE; Region: FliE; cl09139
1087448005125	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
1087448005126	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1087448005127	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1087448005128	Flagellar basal body protein [Cell motility and secretion]; Region: FlgB; COG1815
1087448005129	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
1087448005130	transcriptional repressor CodY; Validated; Region: PRK04158
1087448005131	CodY GAF-like domain; Region: CodY; pfam06018
1087448005132	CodY helix-turn-helix domain; Region: HTH_CodY; pfam08222
1087448005133	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
1087448005134	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1087448005135	Walker A motif; other site
1087448005136	ATP binding site [chemical binding]; other site
1087448005137	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
1087448005138	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1087448005139	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1087448005140	active site
1087448005141	HslU subunit interaction site [polypeptide binding]; other site
1087448005142	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
1087448005143	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1087448005144	active site
1087448005145	DNA binding site [nucleotide binding]
1087448005146	Int/Topo IB signature motif; other site
1087448005147	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
1087448005148	Glucose inhibited division protein A; Region: GIDA; pfam01134
1087448005149	DNA topoisomerase I; Validated; Region: PRK05582
1087448005150	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1087448005151	active site
1087448005152	interdomain interaction site; other site
1087448005153	putative metal-binding site [ion binding]; other site
1087448005154	nucleotide binding site [chemical binding]; other site
1087448005155	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1087448005156	domain I; other site
1087448005157	DNA binding groove [nucleotide binding]
1087448005158	phosphate binding site [ion binding]; other site
1087448005159	domain II; other site
1087448005160	domain III; other site
1087448005161	nucleotide binding site [chemical binding]; other site
1087448005162	catalytic site [active]
1087448005163	domain IV; other site
1087448005164	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1087448005165	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1087448005166	Probable metal-binding protein (DUF2387); Region: DUF2387; cl01410
1087448005167	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
1087448005168	DNA protecting protein DprA; Region: dprA; TIGR00732
1087448005169	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
1087448005170	CoA binding domain; Region: CoA_binding; pfam02629
1087448005171	CoA-ligase; Region: Ligase_CoA; pfam00549
1087448005172	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
1087448005173	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
1087448005174	CoA-ligase; Region: Ligase_CoA; pfam00549
1087448005175	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
1087448005176	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1087448005177	RNA/DNA hybrid binding site [nucleotide binding]; other site
1087448005178	active site
1087448005179	GTPase YlqF; Reviewed; Region: rbgA; PRK09563
1087448005180	Circularly permuted YlqF GTPase; Region: YlqF; cd01856
1087448005181	GTP/Mg2+ binding site [chemical binding]; other site
1087448005182	G4 box; other site
1087448005183	G5 box; other site
1087448005184	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1087448005185	G1 box; other site
1087448005186	Switch I region; other site
1087448005187	G2 box; other site
1087448005188	G3 box; other site
1087448005189	Switch II region; other site
1087448005190	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1087448005191	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1087448005192	Catalytic site [active]
1087448005193	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1087448005194	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1087448005195	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1087448005196	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1087448005197	RimM N-terminal domain; Region: RimM; pfam01782
1087448005198	PRC-barrel domain; Region: PRC; pfam05239
1087448005199	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1087448005200	signal recognition particle protein; Provisional; Region: PRK10867
1087448005201	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1087448005202	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1087448005203	P loop; other site
1087448005204	GTP binding site [chemical binding]; other site
1087448005205	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1087448005206	putative DNA-binding protein; Validated; Region: PRK00118
1087448005207	Putative helix-turn-helix protein, YlxM / p13 like; Region: UPF0122; pfam04297
1087448005208	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1087448005209	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1087448005210	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1087448005211	P loop; other site
1087448005212	GTP binding site [chemical binding]; other site
1087448005213	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
1087448005214	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
1087448005215	Walker A/P-loop; other site
1087448005216	ATP binding site [chemical binding]; other site
1087448005217	Q-loop/lid; other site
1087448005218	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; smart00968
1087448005219	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
1087448005220	ABC transporter signature motif; other site
1087448005221	Walker B; other site
1087448005222	D-loop; other site
1087448005223	H-loop/switch region; other site
1087448005224	Protein of unknown function (DUF1128); Region: DUF1128; cl11553
1087448005225	ribonuclease III; Reviewed; Region: rnc; PRK00102
1087448005226	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1087448005227	dimerization interface [polypeptide binding]; other site
1087448005228	active site
1087448005229	metal binding site [ion binding]; metal-binding site
1087448005230	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1087448005231	dsRNA binding site [nucleotide binding]; other site
1087448005232	acyl carrier protein; Provisional; Region: acpP; PRK00982
1087448005233	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1087448005234	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1087448005235	NAD(P) binding site [chemical binding]; other site
1087448005236	homotetramer interface [polypeptide binding]; other site
1087448005237	homodimer interface [polypeptide binding]; other site
1087448005238	active site
1087448005239	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1087448005240	putative phosphate acyltransferase; Provisional; Region: PRK05331
1087448005241	fatty acid biosynthesis transcriptional regulator; Provisional; Region: PRK04424
1087448005242	HGG motif-containing thioesterase, possibly involved in aromatic compounds catabolism [Secondary metabolites biosynthesis,    transport, and catabolism]; Region: PaaI; COG2050
1087448005243	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
1087448005244	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1087448005245	ssDNA binding site; other site
1087448005246	generic binding surface II; other site
1087448005247	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1087448005248	ATP binding site [chemical binding]; other site
1087448005249	putative Mg++ binding site [ion binding]; other site
1087448005250	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1087448005251	nucleotide binding region [chemical binding]; other site
1087448005252	ATP-binding site [chemical binding]; other site
1087448005253	Serine dehydratase alpha chain; Region: SDH_alpha; cl12120
1087448005254	L-serine deaminase [Amino acid transport and metabolism]; Region: SdaA; COG1760
1087448005255	L-serine dehydratase, iron-sulfur-dependent, beta subunit; Region: sda_beta; TIGR00719
1087448005256	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1087448005257	C-terminal ACT domain of the L-serine dehydratase (LSD), iron-sulfur-dependent, beta subunit; Region: ACT_LSD; cd04903
1087448005258	putative L-serine binding site [chemical binding]; other site
1087448005259	DAK2 domain fusion protein YloV; Region: YloV; TIGR03599
1087448005260	DAK2 domain; Region: Dak2; pfam02734
1087448005261	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1302
1087448005262	S-methylmethionine transporter; Provisional; Region: PRK11387
1087448005263	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
1087448005264	Thiamine pyrophosphokinase; Region: TPK; cd07995
1087448005265	thiamine pyrophosphokinase; Region: thi_PPkinase; TIGR01378
1087448005266	active site
1087448005267	dimerization interface [polypeptide binding]; other site
1087448005268	thiamine binding site [chemical binding]; other site
1087448005269	Thiamine transporter protein (Thia_YuaJ); Region: Thia_YuaJ; pfam09515
1087448005270	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1087448005271	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1087448005272	substrate binding site [chemical binding]; other site
1087448005273	hexamer interface [polypeptide binding]; other site
1087448005274	metal binding site [ion binding]; metal-binding site
1087448005275	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
1087448005276	GTPase RsgA; Reviewed; Region: PRK00098
1087448005277	RNA binding site [nucleotide binding]; other site
1087448005278	homodimer interface [polypeptide binding]; other site
1087448005279	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
1087448005280	GTPase/Zn-binding domain interface [polypeptide binding]; other site
1087448005281	GTP/Mg2+ binding site [chemical binding]; other site
1087448005282	G4 box; other site
1087448005283	G5 box; other site
1087448005284	G1 box; other site
1087448005285	Switch I region; other site
1087448005286	G2 box; other site
1087448005287	G3 box; other site
1087448005288	Switch II region; other site
1087448005289	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
1087448005290	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
1087448005291	active site
1087448005292	ATP binding site [chemical binding]; other site
1087448005293	substrate binding site [chemical binding]; other site
1087448005294	activation loop (A-loop); other site
1087448005295	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2815
1087448005296	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1087448005297	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1087448005298	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1087448005299	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
1087448005300	Protein phosphatase 2C; Region: PP2C; pfam00481
1087448005301	active site
1087448005302	16S rRNA methyltransferase B; Provisional; Region: PRK14902
1087448005303	NusB family; Region: NusB; pfam01029
1087448005304	putative RNA binding site [nucleotide binding]; other site
1087448005305	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1087448005306	S-adenosylmethionine binding site [chemical binding]; other site
1087448005307	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1087448005308	active site
1087448005309	catalytic residues [active]
1087448005310	metal binding site [ion binding]; metal-binding site
1087448005311	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1087448005312	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1087448005313	putative active site [active]
1087448005314	substrate binding site [chemical binding]; other site
1087448005315	putative cosubstrate binding site; other site
1087448005316	catalytic site [active]
1087448005317	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1087448005318	substrate binding site [chemical binding]; other site
1087448005319	Primosomal protein N' (replication factor Y) - superfamily II helicase [DNA replication, recombination, and repair]; Region: PriA; COG1198
1087448005320	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1087448005321	ATP binding site [chemical binding]; other site
1087448005322	putative Mg++ binding site [ion binding]; other site
1087448005323	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1087448005324	nucleotide binding region [chemical binding]; other site
1087448005325	ATP-binding site [chemical binding]; other site
1087448005326	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
1087448005327	Flavoprotein; Region: Flavoprotein; pfam02441
1087448005328	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
1087448005329	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
1087448005330	Guanylate kinase; Region: Guanylate_kin; pfam00625
1087448005331	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1087448005332	catalytic site [active]
1087448005333	G-X2-G-X-G-K; other site
1087448005334	Fibronectin-binding protein A N-terminus (FbpA); Region: FbpA; pfam05833
1087448005335	Domain of unknown function (DUF814); Region: DUF814; pfam05670
1087448005336	Bacterial protein of unknown function (DUF939); Region: DUF939; pfam06081
1087448005337	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
1087448005338	metal-dependent hydrolase; Provisional; Region: PRK00685
1087448005339	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1087448005340	Predicted transcriptional regulators [Transcription]; Region: COG1733
1087448005341	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1087448005342	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1087448005343	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
1087448005344	active site
1087448005345	metal binding site [ion binding]; metal-binding site
1087448005346	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1087448005347	Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR5; cd08271
1087448005348	putative NAD(P) binding site [chemical binding]; other site
1087448005349	substrate binding site [chemical binding]; other site
1087448005350	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
1087448005351	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1087448005352	active site
1087448005353	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1087448005354	active site
1087448005355	dimer interface [polypeptide binding]; other site
1087448005356	dihydroorotate dehydrogenase (subfamily 1) family protein; Region: pyrD_sub1_fam; TIGR01037
1087448005357	Dihydroorotate dehydrogenase (DHOD) class 1B FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1B_like; cd04740
1087448005358	heterodimer interface [polypeptide binding]; other site
1087448005359	active site
1087448005360	FMN binding site [chemical binding]; other site
1087448005361	homodimer interface [polypeptide binding]; other site
1087448005362	substrate binding site [chemical binding]; other site
1087448005363	dihydroorotate dehydrogenase electron transfer subunit; Reviewed; Region: PRK00054
1087448005364	FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate to...; Region: DHOD_e_trans; cd06218
1087448005365	FAD binding pocket [chemical binding]; other site
1087448005366	FAD binding motif [chemical binding]; other site
1087448005367	phosphate binding motif [ion binding]; other site
1087448005368	beta-alpha-beta structure motif; other site
1087448005369	NAD binding pocket [chemical binding]; other site
1087448005370	Iron coordination center [ion binding]; other site
1087448005371	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
1087448005372	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1087448005373	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1087448005374	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
1087448005375	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1087448005376	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1087448005377	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
1087448005378	IMP binding site; other site
1087448005379	dimer interface [polypeptide binding]; other site
1087448005380	interdomain contacts; other site
1087448005381	partial ornithine binding site; other site
1087448005382	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
1087448005383	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; pfam00988
1087448005384	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1087448005385	catalytic site [active]
1087448005386	subunit interface [polypeptide binding]; other site
1087448005387	dihydroorotase; Validated; Region: pyrC; PRK09357
1087448005388	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1087448005389	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
1087448005390	active site
1087448005391	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
1087448005392	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1087448005393	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1087448005394	uracil transporter; Provisional; Region: PRK10720
1087448005395	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
1087448005396	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1087448005397	active site
1087448005398	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1087448005399	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1087448005400	RNA binding surface [nucleotide binding]; other site
1087448005401	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1087448005402	active site
1087448005403	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
1087448005404	lipoprotein signal peptidase; Provisional; Region: PRK14787
1087448005405	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
1087448005406	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1087448005407	active site
1087448005408	HIGH motif; other site
1087448005409	nucleotide binding site [chemical binding]; other site
1087448005410	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1087448005411	active site
1087448005412	KMSKS motif; other site
1087448005413	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
1087448005414	tRNA binding surface [nucleotide binding]; other site
1087448005415	anticodon binding site; other site
1087448005416	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1087448005417	DivIVA protein; Region: DivIVA; pfam05103
1087448005418	DivIVA domain; Region: DivI1A_domain; TIGR03544
1087448005419	Uncharacterized conserved protein, contains S4-like domain [Function unknown]; Region: COG2302
1087448005420	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1087448005421	RNA binding surface [nucleotide binding]; other site
1087448005422	YGGT family; Region: YGGT; pfam02325
1087448005423	Protein of unknown function (DUF552); Region: DUF552; pfam04472
1087448005424	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
1087448005425	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1087448005426	catalytic residue [active]
1087448005427	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
1087448005428	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; pfam02578
1087448005429	cell division protein FtsZ; Validated; Region: PRK09330
1087448005430	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1087448005431	nucleotide binding site [chemical binding]; other site
1087448005432	SulA interaction site; other site
1087448005433	cell division protein FtsA; Region: ftsA; TIGR01174
1087448005434	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1087448005435	nucleotide binding site [chemical binding]; other site
1087448005436	SHS2 domain inserted in FTSA; Region: SHS2_FTSA; pfam02491
1087448005437	Cell division protein FtsA; Region: FtsA; pfam14450
1087448005438	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
1087448005439	Cell division protein FtsQ; Region: FtsQ; pfam03799
1087448005440	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1087448005441	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1087448005442	active site
1087448005443	homodimer interface [polypeptide binding]; other site
1087448005444	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK02472
1087448005445	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1087448005446	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1087448005447	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1087448005448	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1087448005449	Mg++ binding site [ion binding]; other site
1087448005450	putative catalytic motif [active]
1087448005451	putative substrate binding site [chemical binding]; other site
1087448005452	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
1087448005453	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1087448005454	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1087448005455	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1087448005456	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
1087448005457	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1087448005458	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1087448005459	PASTA domain of PBP2x-like proteins, first repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_1; cd06576
1087448005460	PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575
1087448005461	Cell division protein FtsL; Region: FtsL; cl11433
1087448005462	MraW methylase family; Region: Methyltransf_5; pfam01795
1087448005463	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1087448005464	Uncharacterized protein conserved in bacteria (DUF2317); Region: DUF2317; pfam10079
1087448005465	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4365
1087448005466	Protein of unknown function (DUF3397); Region: DUF3397; pfam11877
1087448005467	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
1087448005468	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1087448005469	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1087448005470	Uncharacterized ACR, COG1399; Region: DUF177; pfam02620
1087448005471	hypothetical protein; Provisional; Region: PRK13670
1087448005472	HIGH Nucleotidyl Transferase; Region: HIGH_NTase1; cl17673
1087448005473	Predicted secreted protein containing a PDZ domain [Signal transduction mechanisms]; Region: SdrC; COG3480
1087448005474	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1087448005475	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1087448005476	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
1087448005477	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1087448005478	active site
1087448005479	(T/H)XGH motif; other site
1087448005480	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
1087448005481	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1087448005482	S-adenosylmethionine binding site [chemical binding]; other site
1087448005483	Uncharacterized protein conserved in bacteria (DUF2129); Region: DUF2129; pfam09902
1087448005484	Protein of unknown function (DUF964); Region: DUF964; pfam06133
1087448005485	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1087448005486	YugN-like family; Region: YugN; pfam08868
1087448005487	Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999
1087448005488	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
1087448005489	Cu(I) binding site [ion binding]; other site
1087448005490	Protein of unknown function (DUF420); Region: DUF420; pfam04238
1087448005491	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG); Region: Caa3_CtaG; cl09173
1087448005492	Prokaryotic Cytochrome C oxidase subunit IV; Region: COX4_pro; cl01204
1087448005493	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
1087448005494	Subunit I/III interface [polypeptide binding]; other site
1087448005495	Subunit III/IV interface [polypeptide binding]; other site
1087448005496	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
1087448005497	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
1087448005498	D-pathway; other site
1087448005499	Putative ubiquinol binding site [chemical binding]; other site
1087448005500	Low-spin heme (heme b) binding site [chemical binding]; other site
1087448005501	Putative water exit pathway; other site
1087448005502	Binuclear center (heme o3/CuB) [ion binding]; other site
1087448005503	K-pathway; other site
1087448005504	Putative proton exit pathway; other site
1087448005505	Heme/copper-type cytochrome/quinol oxidases, subunit 2 [Energy production and conversion]; Region: CyoA; COG1622
1087448005506	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
1087448005507	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
1087448005508	protoheme IX farnesyltransferase; Provisional; Region: PRK04375
1087448005509	UbiA prenyltransferase family; Region: UbiA; pfam01040
1087448005510	Cytochrome oxidase assembly protein; Region: COX15-CtaA; pfam02628
1087448005511	Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]; Region: CtaA; COG1612
1087448005512	Deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair]; Region: PhrB; COG0415
1087448005513	DNA photolyase; Region: DNA_photolyase; pfam00875
1087448005514	pyruvate carboxylase; Reviewed; Region: PRK12999
1087448005515	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1087448005516	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1087448005517	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1087448005518	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
1087448005519	active site
1087448005520	catalytic residues [active]
1087448005521	metal binding site [ion binding]; metal-binding site
1087448005522	homodimer binding site [polypeptide binding]; other site
1087448005523	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1087448005524	carboxyltransferase (CT) interaction site; other site
1087448005525	biotinylation site [posttranslational modification]; other site
1087448005526	Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772
1087448005527	hypothetical protein; Provisional; Region: PRK13666
1087448005528	NYN ribonuclease and ATPase of PhoH family domains [General    function prediction only]; Region: COG1875
1087448005529	PIN domain of bacterial Smg6-like homologs with PhoH-like ATPase domains; Region: PIN_PhoHL-ATPase; cd09883
1087448005530	putative active site [active]
1087448005531	PhoH-like protein; Region: PhoH; pfam02562
1087448005532	hypothetical protein; Provisional; Region: PRK06733
1087448005533	YlaH-like protein; Region: YlaH; pfam14036
1087448005534	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
1087448005535	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1087448005536	G1 box; other site
1087448005537	putative GEF interaction site [polypeptide binding]; other site
1087448005538	GTP/Mg2+ binding site [chemical binding]; other site
1087448005539	Switch I region; other site
1087448005540	G2 box; other site
1087448005541	G3 box; other site
1087448005542	Switch II region; other site
1087448005543	G4 box; other site
1087448005544	G5 box; other site
1087448005545	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1087448005546	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1087448005547	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1087448005548	Inositol-monophosphatase-like domains. This family of phosphatases is dependent on bivalent metal ions such as Mg++, and many members are inhibited by Li+ (which is thought to displace a bivalent ion in the active site). Substrates include fructose-1; Region: IMPase_like; cd01637
1087448005549	active site
1087448005550	hypothetical protein; Provisional; Region: PRK04387
1087448005551	Arginine/lysine/ornithine decarboxylases [Amino acid transport and metabolism]; Region: LdcC; COG1982
1087448005552	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1087448005553	homodimer interface [polypeptide binding]; other site
1087448005554	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1087448005555	catalytic residue [active]
1087448005556	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1087448005557	Protein of unknown function (DUF3055); Region: DUF3055; pfam11256
1087448005558	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06416
1087448005559	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1087448005560	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1087448005561	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1087448005562	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
1087448005563	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1087448005564	E3 interaction surface; other site
1087448005565	lipoyl attachment site [posttranslational modification]; other site
1087448005566	e3 binding domain; Region: E3_binding; pfam02817
1087448005567	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1087448005568	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
1087448005569	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
1087448005570	alpha subunit interface [polypeptide binding]; other site
1087448005571	TPP binding site [chemical binding]; other site
1087448005572	heterodimer interface [polypeptide binding]; other site
1087448005573	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1087448005574	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_x; TIGR03181
1087448005575	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
1087448005576	TPP-binding site [chemical binding]; other site
1087448005577	tetramer interface [polypeptide binding]; other site
1087448005578	heterodimer interface [polypeptide binding]; other site
1087448005579	phosphorylation loop region [posttranslational modification]
1087448005580	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1087448005581	active site
1087448005582	catalytic residues [active]
1087448005583	metal binding site [ion binding]; metal-binding site
1087448005584	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
1087448005585	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
1087448005586	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
1087448005587	Protein of unknown function (DUF1447); Region: DUF1447; pfam07288
1087448005588	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1087448005589	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1087448005590	active site
1087448005591	motif I; other site
1087448005592	motif II; other site
1087448005593	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1087448005594	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
1087448005595	TrkA-N domain; Region: TrkA_N; pfam02254
1087448005596	TrkA-C domain; Region: TrkA_C; pfam02080
1087448005597	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
1087448005598	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
1087448005599	M20 Peptidase Aminoacyclase-1 YkuR-like proteins, including YkuR and Ama/HipO/HyuC proteins; Region: M20_Acy1_YkuR_like; cd05670
1087448005600	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1087448005601	metal binding site [ion binding]; metal-binding site
1087448005602	putative dimer interface [polypeptide binding]; other site
1087448005603	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1087448005604	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1087448005605	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1087448005606	dimerization interface [polypeptide binding]; other site
1087448005607	Disulfide bond formation protein DsbB; Region: DsbB; cl00649
1087448005608	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
1087448005609	homodimer interface [polypeptide binding]; other site
1087448005610	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
1087448005611	NAD binding pocket [chemical binding]; other site
1087448005612	ATP binding pocket [chemical binding]; other site
1087448005613	Mg binding site [ion binding]; other site
1087448005614	active-site loop [active]
1087448005615	Scaffold protein Nfu/NifU N terminal; Region: Nfu_N; cl07364
1087448005616	Virulence factor; Region: Virulence_fact; pfam13769
1087448005617	HEAT repeats; Region: HEAT_2; pfam13646
1087448005618	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1087448005619	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1087448005620	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1087448005621	Branched-chain amino acid transport protein; Region: Branch_AA_trans; pfam05525
1087448005622	EDD domain protein, DegV family; Region: DegV; TIGR00762
1087448005623	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
1087448005624	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
1087448005625	tetramer interfaces [polypeptide binding]; other site
1087448005626	binuclear metal-binding site [ion binding]; other site
1087448005627	hypothetical protein; Provisional; Region: PRK13679
1087448005628	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1087448005629	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK08594
1087448005630	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
1087448005631	NAD binding site [chemical binding]; other site
1087448005632	homotetramer interface [polypeptide binding]; other site
1087448005633	homodimer interface [polypeptide binding]; other site
1087448005634	substrate binding site [chemical binding]; other site
1087448005635	active site
1087448005636	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
1087448005637	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1087448005638	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1087448005639	active site
1087448005640	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK04885
1087448005641	ATP-NAD kinase; Region: NAD_kinase; pfam01513
1087448005642	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1087448005643	synthetase active site [active]
1087448005644	NTP binding site [chemical binding]; other site
1087448005645	metal binding site [ion binding]; metal-binding site
1087448005646	Uncharacterized subgroup 1 of the CYTH-like superfamily; Region: CYTH-like_Pase_1; cd07762
1087448005647	putative active site [active]
1087448005648	putative metal binding residues [ion binding]; other site
1087448005649	signature motif; other site
1087448005650	putative triphosphate binding site [ion binding]; other site
1087448005651	Thioredoxin; Region: Thioredoxin_5; pfam13743
1087448005652	oligoendopeptidase F; Region: pepF; TIGR00181
1087448005653	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608
1087448005654	active site
1087448005655	Zn binding site [ion binding]; other site
1087448005656	Competence protein CoiA-like family; Region: CoiA; cl11541
1087448005657	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
1087448005658	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
1087448005659	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
1087448005660	putative active site [active]
1087448005661	catalytic site [active]
1087448005662	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
1087448005663	putative active site [active]
1087448005664	catalytic site [active]
1087448005665	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
1087448005666	classical (c) SDRs; Region: SDR_c; cd05233
1087448005667	NAD(P) binding site [chemical binding]; other site
1087448005668	active site
1087448005669	adaptor protein; Provisional; Region: PRK02315
1087448005670	Arsenate Reductase (ArsC) family, Spx subfamily; Spx is a unique RNA polymerase (RNAP)-binding protein present in bacilli and some mollicutes. It inhibits transcription by binding to the C-terminal domain of the alpha subunit of RNAP, disrupting complex...; Region: ArsC_Spx; cd03032
1087448005671	ArsC family; Region: ArsC; pfam03960
1087448005672	putative catalytic residues [active]
1087448005673	thiol/disulfide switch; other site
1087448005674	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
1087448005675	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1087448005676	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1087448005677	Walker A/P-loop; other site
1087448005678	ATP binding site [chemical binding]; other site
1087448005679	Q-loop/lid; other site
1087448005680	ABC transporter signature motif; other site
1087448005681	Walker B; other site
1087448005682	D-loop; other site
1087448005683	H-loop/switch region; other site
1087448005684	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
1087448005685	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1087448005686	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1087448005687	Walker A/P-loop; other site
1087448005688	ATP binding site [chemical binding]; other site
1087448005689	Q-loop/lid; other site
1087448005690	ABC transporter signature motif; other site
1087448005691	Walker B; other site
1087448005692	D-loop; other site
1087448005693	H-loop/switch region; other site
1087448005694	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
1087448005695	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
1087448005696	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1087448005697	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1087448005698	dimer interface [polypeptide binding]; other site
1087448005699	conserved gate region; other site
1087448005700	putative PBP binding loops; other site
1087448005701	ABC-ATPase subunit interface; other site
1087448005702	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1087448005703	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1087448005704	dimer interface [polypeptide binding]; other site
1087448005705	conserved gate region; other site
1087448005706	putative PBP binding loops; other site
1087448005707	ABC-ATPase subunit interface; other site
1087448005708	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1087448005709	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1087448005710	peptide binding site [polypeptide binding]; other site
1087448005711	Domain of unknown function (DUF3899); Region: DUF3899; pfam13038
1087448005712	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1087448005713	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1087448005714	active site
1087448005715	HIGH motif; other site
1087448005716	dimer interface [polypeptide binding]; other site
1087448005717	KMSKS motif; other site
1087448005718	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
1087448005719	Helix-turn-helix domain; Region: HTH_38; pfam13936
1087448005720	Integrase core domain; Region: rve; pfam00665
1087448005721	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1087448005722	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1087448005723	peptide binding site [polypeptide binding]; other site
1087448005724	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
1087448005725	Helix-turn-helix domain; Region: HTH_38; pfam13936
1087448005726	Integrase core domain; Region: rve; pfam00665
1087448005727	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
1087448005728	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1087448005729	dimer interface [polypeptide binding]; other site
1087448005730	active site
1087448005731	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1087448005732	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1087448005733	dimer interface [polypeptide binding]; other site
1087448005734	active site
1087448005735	CoA binding pocket [chemical binding]; other site
1087448005736	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
1087448005737	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
1087448005738	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1087448005739	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1087448005740	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1087448005741	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
1087448005742	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
1087448005743	ATP-binding site [chemical binding]; other site
1087448005744	Sugar specificity; other site
1087448005745	Pyrimidine base specificity; other site
1087448005746	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
1087448005747	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1087448005748	S-adenosylmethionine binding site [chemical binding]; other site
1087448005749	YceG-like family; Region: YceG; pfam02618
1087448005750	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1087448005751	dimerization interface [polypeptide binding]; other site
1087448005752	hypothetical protein; Provisional; Region: PRK13678
1087448005753	Protein of unknown function (DUF1292); Region: DUF1292; cl01608
1087448005754	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
1087448005755	hypothetical protein; Provisional; Region: PRK05473
1087448005756	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1087448005757	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1087448005758	motif 1; other site
1087448005759	active site
1087448005760	motif 2; other site
1087448005761	motif 3; other site
1087448005762	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1087448005763	DHHA1 domain; Region: DHHA1; pfam02272
1087448005764	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
1087448005765	AAA domain; Region: AAA_30; pfam13604
1087448005766	Family description; Region: UvrD_C_2; pfam13538
1087448005767	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
1087448005768	active site
1087448005769	metal binding site [ion binding]; metal-binding site
1087448005770	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1087448005771	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1087448005772	binding surface
1087448005773	TPR repeat; Region: TPR_11; pfam13414
1087448005774	TPR motif; other site
1087448005775	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1087448005776	binding surface
1087448005777	TPR motif; other site
1087448005778	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
1087448005779	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1087448005780	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
1087448005781	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1087448005782	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1087448005783	catalytic residue [active]
1087448005784	Rrf2 family protein; Region: rrf2_super; TIGR00738
1087448005785	Transcriptional regulator; Region: Rrf2; pfam02082
1087448005786	recombination factor protein RarA; Reviewed; Region: PRK13342
1087448005787	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1087448005788	Walker A motif; other site
1087448005789	ATP binding site [chemical binding]; other site
1087448005790	Walker B motif; other site
1087448005791	arginine finger; other site
1087448005792	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1087448005793	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179
1087448005794	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
1087448005795	putative ATP binding site [chemical binding]; other site
1087448005796	putative substrate interface [chemical binding]; other site
1087448005797	cryptochrome, DASH family; Region: crypto_DASH; TIGR02765
1087448005798	DNA photolyase; Region: DNA_photolyase; pfam00875
1087448005799	Alkyladenine DNA glycosylase catalyzes the first step in base excision repair; Region: AAG; cd00540
1087448005800	active site
1087448005801	DNA binding site [nucleotide binding]
1087448005802	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1087448005803	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1087448005804	dimer interface [polypeptide binding]; other site
1087448005805	anticodon binding site; other site
1087448005806	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1087448005807	homodimer interface [polypeptide binding]; other site
1087448005808	motif 1; other site
1087448005809	active site
1087448005810	motif 2; other site
1087448005811	GAD domain; Region: GAD; pfam02938
1087448005812	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1087448005813	active site
1087448005814	motif 3; other site
1087448005815	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1087448005816	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1087448005817	dimer interface [polypeptide binding]; other site
1087448005818	motif 1; other site
1087448005819	active site
1087448005820	motif 2; other site
1087448005821	motif 3; other site
1087448005822	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1087448005823	anticodon binding site; other site
1087448005824	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
1087448005825	putative active site [active]
1087448005826	dimerization interface [polypeptide binding]; other site
1087448005827	putative tRNAtyr binding site [nucleotide binding]; other site
1087448005828	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1087448005829	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1087448005830	Zn2+ binding site [ion binding]; other site
1087448005831	Mg2+ binding site [ion binding]; other site
1087448005832	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1087448005833	synthetase active site [active]
1087448005834	NTP binding site [chemical binding]; other site
1087448005835	metal binding site [ion binding]; metal-binding site
1087448005836	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1087448005837	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1087448005838	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1087448005839	active site
1087448005840	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
1087448005841	DHH family; Region: DHH; pfam01368
1087448005842	Single-strand DNA-specific exonuclease, C terminal domain; Region: ssDNA-exonuc_C; pfam10141
1087448005843	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
1087448005844	Protein export membrane protein; Region: SecD_SecF; pfam02355
1087448005845	protein-export membrane protein SecD; Region: secD; TIGR01129
1087448005846	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1087448005847	Preprotein translocase subunit; Region: YajC; pfam02699
1087448005848	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1087448005849	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
1087448005850	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
1087448005851	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1087448005852	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1087448005853	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1087448005854	Walker A motif; other site
1087448005855	ATP binding site [chemical binding]; other site
1087448005856	Walker B motif; other site
1087448005857	arginine finger; other site
1087448005858	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1087448005859	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1087448005860	RuvA N terminal domain; Region: RuvA_N; pfam01330
1087448005861	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1087448005862	quinolinate synthetase; Provisional; Region: PRK09375
1087448005863	L-aspartate oxidase; Provisional; Region: PRK06175
1087448005864	Aspartate oxidase [Coenzyme metabolism]; Region: NadB; COG0029
1087448005865	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1087448005866	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1087448005867	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1087448005868	catalytic residue [active]
1087448005869	Predicted small molecule binding protein (contains 3H domain) [General function prediction only]; Region: COG1827
1087448005870	HTH domain; Region: HTH_11; pfam08279
1087448005871	3H domain; Region: 3H; pfam02829
1087448005872	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1087448005873	Domain of unknown function DUF21; Region: DUF21; pfam01595
1087448005874	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1087448005875	Transporter associated domain; Region: CorC_HlyC; smart01091
1087448005876	GTPase CgtA; Reviewed; Region: obgE; PRK12297
1087448005877	GTP1/OBG; Region: GTP1_OBG; pfam01018
1087448005878	Obg GTPase; Region: Obg; cd01898
1087448005879	G1 box; other site
1087448005880	GTP/Mg2+ binding site [chemical binding]; other site
1087448005881	Switch I region; other site
1087448005882	G2 box; other site
1087448005883	G3 box; other site
1087448005884	Switch II region; other site
1087448005885	G4 box; other site
1087448005886	G5 box; other site
1087448005887	Domain of unknown function (DUF1967); Region: DUF1967; pfam09269
1087448005888	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1087448005889	Protein of unknown function (DUF464); Region: DUF464; pfam04327
1087448005890	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
1087448005891	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1087448005892	Ribonuclease E/G family; Region: RNase_E_G; pfam10150
1087448005893	Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]; Region: MinD; COG2894
1087448005894	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
1087448005895	Switch I; other site
1087448005896	Switch II; other site
1087448005897	septum formation inhibitor; Reviewed; Region: minC; PRK00513
1087448005898	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
1087448005899	rod shape-determining protein MreC; Provisional; Region: PRK13922
1087448005900	rod shape-determining protein MreC; Region: MreC; pfam04085
1087448005901	rod shape-determining protein MreB; Provisional; Region: PRK13927
1087448005902	MreB and similar proteins; Region: MreB_like; cd10225
1087448005903	nucleotide binding site [chemical binding]; other site
1087448005904	Mg binding site [ion binding]; other site
1087448005905	putative protofilament interaction site [polypeptide binding]; other site
1087448005906	RodZ interaction site [polypeptide binding]; other site
1087448005907	hypothetical protein; Reviewed; Region: PRK00024
1087448005908	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1087448005909	MPN+ (JAMM) motif; other site
1087448005910	Zinc-binding site [ion binding]; other site
1087448005911	Maf-like protein; Region: Maf; pfam02545
1087448005912	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1087448005913	active site
1087448005914	dimer interface [polypeptide binding]; other site
1087448005915	Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972
1087448005916	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
1087448005917	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
1087448005918	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
1087448005919	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1087448005920	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1087448005921	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
1087448005922	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1087448005923	Walker A motif; other site
1087448005924	ATP binding site [chemical binding]; other site
1087448005925	Walker B motif; other site
1087448005926	type IV-A pilus assembly ATPase PilB; Region: type_IV_pilB; TIGR02538
1087448005927	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
1087448005928	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
1087448005929	Walker A motif; other site
1087448005930	ATP binding site [chemical binding]; other site
1087448005931	Walker B motif; other site
1087448005932	VanW like protein; Region: VanW; pfam04294
1087448005933	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1087448005934	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
1087448005935	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1087448005936	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1087448005937	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1087448005938	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1087448005939	active site
1087448005940	HIGH motif; other site
1087448005941	nucleotide binding site [chemical binding]; other site
1087448005942	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1087448005943	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1087448005944	active site
1087448005945	KMSKS motif; other site
1087448005946	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1087448005947	tRNA binding surface [nucleotide binding]; other site
1087448005948	anticodon binding site; other site
1087448005949	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1087448005950	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
1087448005951	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1087448005952	inhibitor-cofactor binding pocket; inhibition site
1087448005953	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1087448005954	catalytic residue [active]
1087448005955	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
1087448005956	dimer interface [polypeptide binding]; other site
1087448005957	active site
1087448005958	Schiff base residues; other site
1087448005959	Uroporphyrinogen-III synthase [Coenzyme metabolism]; Region: HemD; COG1587
1087448005960	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1087448005961	active site
1087448005962	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
1087448005963	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
1087448005964	domain interfaces; other site
1087448005965	active site
1087448005966	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
1087448005967	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
1087448005968	tRNA; other site
1087448005969	putative tRNA binding site [nucleotide binding]; other site
1087448005970	putative NADP binding site [chemical binding]; other site
1087448005971	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
1087448005972	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1087448005973	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1087448005974	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1087448005975	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
1087448005976	DXD motif; other site
1087448005977	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1087448005978	Response regulator receiver domain; Region: Response_reg; pfam00072
1087448005979	active site
1087448005980	phosphorylation site [posttranslational modification]
1087448005981	intermolecular recognition site; other site
1087448005982	dimerization interface [polypeptide binding]; other site
1087448005983	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1087448005984	G1 box; other site
1087448005985	GTP/Mg2+ binding site [chemical binding]; other site
1087448005986	Switch I region; other site
1087448005987	G2 box; other site
1087448005988	G3 box; other site
1087448005989	Switch II region; other site
1087448005990	G4 box; other site
1087448005991	G5 box; other site
1087448005992	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
1087448005993	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1087448005994	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1087448005995	Walker A motif; other site
1087448005996	ATP binding site [chemical binding]; other site
1087448005997	Walker B motif; other site
1087448005998	arginine finger; other site
1087448005999	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1087448006000	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1087448006001	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
1087448006002	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1087448006003	Walker A motif; other site
1087448006004	ATP binding site [chemical binding]; other site
1087448006005	Walker B motif; other site
1087448006006	arginine finger; other site
1087448006007	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1087448006008	trigger factor; Provisional; Region: tig; PRK01490
1087448006009	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1087448006010	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1087448006011	Predicted membrane protein [Function unknown]; Region: COG1511
1087448006012	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
1087448006013	active site
1087448006014	metal binding site [ion binding]; metal-binding site
1087448006015	homotetramer interface [polypeptide binding]; other site
1087448006016	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1087448006017	active site
1087448006018	dimerization interface [polypeptide binding]; other site
1087448006019	ribonuclease PH; Reviewed; Region: rph; PRK00173
1087448006020	Ribonuclease PH; Region: RNase_PH_bact; cd11362
1087448006021	hexamer interface [polypeptide binding]; other site
1087448006022	active site
1087448006023	glutamate racemase; Provisional; Region: PRK00865
1087448006024	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1087448006025	dimerization domain swap beta strand [polypeptide binding]; other site
1087448006026	regulatory protein interface [polypeptide binding]; other site
1087448006027	active site
1087448006028	regulatory phosphorylation site [posttranslational modification]; other site
1087448006029	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1087448006030	active site
1087448006031	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK08640
1087448006032	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1087448006033	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1087448006034	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08641
1087448006035	L-aspartate oxidase; Provisional; Region: PRK06175
1087448006036	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1087448006037	Succinate:quinone oxidoreductase (SQR) Type B subfamily 1, transmembrane subunit; composed of proteins similar to Bacillus subtilis SQR. SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. Bacillus subtilis...; Region: SQR_TypeB_1_TM; cd03497
1087448006038	putative Iron-sulfur protein interface [polypeptide binding]; other site
1087448006039	succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; Region: sdhC_b558_fam; TIGR02046
1087448006040	proximal heme binding site [chemical binding]; other site
1087448006041	distal heme binding site [chemical binding]; other site
1087448006042	putative dimer interface [polypeptide binding]; other site
1087448006043	Protein of unknown function (DUF2507); Region: DUF2507; pfam10702
1087448006044	Pleckstrin homology (PH)-like domains in bacteria (PHb); Region: PH-like_bacteria; cd13225
1087448006045	pentamer interface [polypeptide binding]; other site
1087448006046	dodecaamer interface [polypeptide binding]; other site
1087448006047	YvbH-like oligomerisation region; Region: YvbH_ext; pfam11724
1087448006048	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
1087448006049	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1087448006050	GIY-YIG motif/motif A; other site
1087448006051	active site
1087448006052	catalytic site [active]
1087448006053	putative DNA binding site [nucleotide binding]; other site
1087448006054	metal binding site [ion binding]; metal-binding site
1087448006055	UvrB/uvrC motif; Region: UVR; pfam02151
1087448006056	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1087448006057	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1087448006058	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1087448006059	catalytic residues [active]
1087448006060	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
1087448006061	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
1087448006062	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1087448006063	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1087448006064	Ligand binding site [chemical binding]; other site
1087448006065	Electron transfer flavoprotein domain; Region: ETF; pfam01012
1087448006066	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK06710
1087448006067	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
1087448006068	acyl-activating enzyme (AAE) consensus motif; other site
1087448006069	putative AMP binding site [chemical binding]; other site
1087448006070	putative active site [active]
1087448006071	putative CoA binding site [chemical binding]; other site
1087448006072	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1087448006073	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1087448006074	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1087448006075	Predicted membrane protein [Function unknown]; Region: COG3766
1087448006076	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
1087448006077	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
1087448006078	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
1087448006079	MutS domain III; Region: MutS_III; pfam05192
1087448006080	ATP-binding cassette domain of MutS2; Region: ABC_MutS2; cd03280
1087448006081	Walker A/P-loop; other site
1087448006082	ATP binding site [chemical binding]; other site
1087448006083	Q-loop/lid; other site
1087448006084	ABC transporter signature motif; other site
1087448006085	Walker B; other site
1087448006086	D-loop; other site
1087448006087	H-loop/switch region; other site
1087448006088	Smr domain; Region: Smr; pfam01713
1087448006089	hypothetical protein; Provisional; Region: PRK08609
1087448006090	Nucleotidyltransferase (NT) domain of family X DNA Polymerases; Region: NT_POLXc; cd00141
1087448006091	active site
1087448006092	primer binding site [nucleotide binding]; other site
1087448006093	NTP  binding site [chemical binding]; other site
1087448006094	metal binding triad [ion binding]; metal-binding site
1087448006095	Polymerase and Histidinol Phosphatase domain of bacterial polymerase X; Region: PHP_PolX; cd07436
1087448006096	active site
1087448006097	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
1087448006098	Colicin V production protein; Region: Colicin_V; pfam02674
1087448006099	Cell division protein ZapA; Region: ZapA; cl01146
1087448006100	ribonuclease HIII; Provisional; Region: PRK00996
1087448006101	Domain of unknown function (DUF3378); Region: DUF3378; pfam11858
1087448006102	bacterial Ribonuclease HIII-like; Region: RNase_HII_bacteria_HIII_like; cd06590
1087448006103	RNA/DNA hybrid binding site [nucleotide binding]; other site
1087448006104	active site
1087448006105	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1087448006106	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1087448006107	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1087448006108	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1087448006109	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1087448006110	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1087448006111	active site
1087448006112	phosphorylation site [posttranslational modification]
1087448006113	intermolecular recognition site; other site
1087448006114	dimerization interface [polypeptide binding]; other site
1087448006115	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1087448006116	DNA binding site [nucleotide binding]
1087448006117	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1087448006118	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1087448006119	dimerization interface [polypeptide binding]; other site
1087448006120	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1087448006121	dimer interface [polypeptide binding]; other site
1087448006122	phosphorylation site [posttranslational modification]
1087448006123	Histidine kinase-like ATPases; Region: HATPase_c; smart00387
1087448006124	G-X-G motif; other site
1087448006125	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1087448006126	MarR family; Region: MarR_2; pfam12802
1087448006127	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1087448006128	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1087448006129	putative substrate translocation pore; other site
1087448006130	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1087448006131	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1087448006132	Walker A/P-loop; other site
1087448006133	ATP binding site [chemical binding]; other site
1087448006134	Q-loop/lid; other site
1087448006135	ABC transporter signature motif; other site
1087448006136	Walker B; other site
1087448006137	D-loop; other site
1087448006138	H-loop/switch region; other site
1087448006139	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1087448006140	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1087448006141	FtsX-like permease family; Region: FtsX; pfam02687
1087448006142	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1087448006143	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1087448006144	putative tRNA-binding site [nucleotide binding]; other site
1087448006145	B3/4 domain; Region: B3_4; pfam03483
1087448006146	tRNA synthetase B5 domain; Region: B5; smart00874
1087448006147	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1087448006148	dimer interface [polypeptide binding]; other site
1087448006149	motif 1; other site
1087448006150	motif 3; other site
1087448006151	motif 2; other site
1087448006152	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1087448006153	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1087448006154	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1087448006155	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1087448006156	dimer interface [polypeptide binding]; other site
1087448006157	motif 1; other site
1087448006158	active site
1087448006159	motif 2; other site
1087448006160	motif 3; other site
1087448006161	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
1087448006162	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1087448006163	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1087448006164	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
1087448006165	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
1087448006166	oligomer interface [polypeptide binding]; other site
1087448006167	active site
1087448006168	metal binding site [ion binding]; metal-binding site
1087448006169	dUTPase; Region: dUTPase_2; pfam08761
1087448006170	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in dimeric 2-Deoxyuridine 5'-triphosphate nucleotidohydrolase and similar proteins; Region: NTP-PPase_dUTPase; cd11527
1087448006171	active site
1087448006172	homodimer interface [polypeptide binding]; other site
1087448006173	metal binding site [ion binding]; metal-binding site
1087448006174	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain superfamily; Region: NTP-PPase; cl16941
1087448006175	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1087448006176	23S rRNA binding site [nucleotide binding]; other site
1087448006177	L21 binding site [polypeptide binding]; other site
1087448006178	L13 binding site [polypeptide binding]; other site
1087448006179	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1087448006180	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1087448006181	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1087448006182	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
1087448006183	Clade 1 of the heme-binding enzyme catalase; Region: catalase_clade_1; cd08154
1087448006184	tetramer interface [polypeptide binding]; other site
1087448006185	heme binding pocket [chemical binding]; other site
1087448006186	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1087448006187	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
1087448006188	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
1087448006189	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1087448006190	active site
1087448006191	dimer interface [polypeptide binding]; other site
1087448006192	motif 1; other site
1087448006193	motif 2; other site
1087448006194	motif 3; other site
1087448006195	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1087448006196	anticodon binding site; other site
1087448006197	primosomal protein DnaI; Reviewed; Region: PRK08939
1087448006198	Primosomal protein DnaI N-terminus; Region: DnaI_N; pfam07319
1087448006199	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1087448006200	Walker A motif; other site
1087448006201	ATP binding site [chemical binding]; other site
1087448006202	Walker B motif; other site
1087448006203	arginine finger; other site
1087448006204	Replication initiation/membrane attachment protein [DNA replication, recombination, and repair]; Region: DnaB; COG3611
1087448006205	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
1087448006206	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
1087448006207	ATP cone domain; Region: ATP-cone; pfam03477
1087448006208	S-adenosylmethionine decarboxylase proenzyme; Provisional; Region: PRK03124
1087448006209	glyceraldehyde-3-phosphate dehydrogenase; Validated; Region: PRK07729
1087448006210	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
1087448006211	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1087448006212	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1087448006213	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1087448006214	CoA-binding site [chemical binding]; other site
1087448006215	ATP-binding [chemical binding]; other site
1087448006216	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
1087448006217	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
1087448006218	DNA binding site [nucleotide binding]
1087448006219	catalytic residue [active]
1087448006220	H2TH interface [polypeptide binding]; other site
1087448006221	putative catalytic residues [active]
1087448006222	turnover-facilitating residue; other site
1087448006223	intercalation triad [nucleotide binding]; other site
1087448006224	8OG recognition residue [nucleotide binding]; other site
1087448006225	putative reading head residues; other site
1087448006226	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
1087448006227	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
1087448006228	DNA polymerase I; Provisional; Region: PRK05755
1087448006229	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1087448006230	active site
1087448006231	metal binding site 1 [ion binding]; metal-binding site
1087448006232	putative 5' ssDNA interaction site; other site
1087448006233	metal binding site 3; metal-binding site
1087448006234	metal binding site 2 [ion binding]; metal-binding site
1087448006235	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1087448006236	putative DNA binding site [nucleotide binding]; other site
1087448006237	putative metal binding site [ion binding]; other site
1087448006238	inactive DEDDy 3'-5' exonuclease domain of Bacillus stearothermophilus DNA polymerase I and similar family-A DNA polymerases; Region: DNA_polA_I_Bacillus_like_exo; cd06140
1087448006239	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1087448006240	active site
1087448006241	DNA binding site [nucleotide binding]
1087448006242	catalytic site [active]
1087448006243	HAMP domain; Region: HAMP; pfam00672
1087448006244	dimerization interface [polypeptide binding]; other site
1087448006245	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
1087448006246	PAS domain; Region: PAS; smart00091
1087448006247	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1087448006248	dimer interface [polypeptide binding]; other site
1087448006249	phosphorylation site [posttranslational modification]
1087448006250	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1087448006251	ATP binding site [chemical binding]; other site
1087448006252	G-X-G motif; other site
1087448006253	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1087448006254	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1087448006255	active site
1087448006256	phosphorylation site [posttranslational modification]
1087448006257	intermolecular recognition site; other site
1087448006258	dimerization interface [polypeptide binding]; other site
1087448006259	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1087448006260	DNA binding site [nucleotide binding]
1087448006261	Divergent PAP2 family; Region: DUF212; pfam02681
1087448006262	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
1087448006263	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1087448006264	NAD binding site [chemical binding]; other site
1087448006265	catalytic Zn binding site [ion binding]; other site
1087448006266	structural Zn binding site [ion binding]; other site
1087448006267	malate dehydrogenase; Reviewed; Region: PRK06223
1087448006268	L-lactate dehydrogenase-like malate dehydrogenase proteins; Region: LDH-like_MDH; cd01339
1087448006269	NAD(P) binding site [chemical binding]; other site
1087448006270	dimer interface [polypeptide binding]; other site
1087448006271	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1087448006272	substrate binding site [chemical binding]; other site
1087448006273	isocitrate dehydrogenase; Reviewed; Region: PRK07006
1087448006274	isocitrate dehydrogenase; Validated; Region: PRK07362
1087448006275	Bacillus subtilis (Bs) citrate synthase (CS)-II_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). 2MCS catalyzes the...; Region: BSuCS-II_like; cd06110
1087448006276	dimer interface [polypeptide binding]; other site
1087448006277	Citrate synthase; Region: Citrate_synt; pfam00285
1087448006278	active site
1087448006279	citrylCoA binding site [chemical binding]; other site
1087448006280	oxalacetate/citrate binding site [chemical binding]; other site
1087448006281	coenzyme A binding site [chemical binding]; other site
1087448006282	catalytic triad [active]
1087448006283	Protein of unknown function (DUF441); Region: DUF441; pfam04284
1087448006284	pyruvate kinase; Provisional; Region: PRK06354
1087448006285	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
1087448006286	domain interfaces; other site
1087448006287	active site
1087448006288	Phosphohistidine swiveling domain [Signal transduction mechanisms]; Region: COG3848
1087448006289	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
1087448006290	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
1087448006291	active site
1087448006292	ADP/pyrophosphate binding site [chemical binding]; other site
1087448006293	dimerization interface [polypeptide binding]; other site
1087448006294	allosteric effector site; other site
1087448006295	fructose-1,6-bisphosphate binding site; other site
1087448006296	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
1087448006297	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
1087448006298	Acetyl-CoA carboxylase beta subunit [Lipid metabolism]; Region: AccD; COG0777
1087448006299	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1087448006300	Transcriptional regulators [Transcription]; Region: FadR; COG2186
1087448006301	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1087448006302	DNA-binding site [nucleotide binding]; DNA binding site
1087448006303	DNA polymerase III, alpha subunit [DNA replication, recombination, and repair]; Region: DnaE; COG0587
1087448006304	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III; Region: PHP_PolIIIA; cd07431
1087448006305	active site
1087448006306	PHP Thumb interface [polypeptide binding]; other site
1087448006307	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
1087448006308	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1087448006309	generic binding surface I; other site
1087448006310	generic binding surface II; other site
1087448006311	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
1087448006312	DHH family; Region: DHH; pfam01368
1087448006313	DHHA1 domain; Region: DHHA1; pfam02272
1087448006314	YtpI-like protein; Region: YtpI; pfam14007
1087448006315	Predicted transcriptional regulator containing CBS domains [Transcription]; Region: COG4109
1087448006316	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
1087448006317	DNA-binding site [nucleotide binding]; DNA binding site
1087448006318	DRTGG domain; Region: DRTGG; pfam07085
1087448006319	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with a DRTGG domain upstream. The function of the DRTGG domain, named after its conserved residues, is unknown. CBS is a small domain originally...; Region: CBS_pair_DRTGG_assoc; cd04596
1087448006320	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cd03440
1087448006321	active site 2 [active]
1087448006322	active site 1 [active]
1087448006323	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1087448006324	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1087448006325	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
1087448006326	active site
1087448006327	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK12825
1087448006328	classical (c) SDRs; Region: SDR_c; cd05233
1087448006329	NAD(P) binding site [chemical binding]; other site
1087448006330	active site
1087448006331	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1087448006332	Ligand Binding Site [chemical binding]; other site
1087448006333	Bacterial SH3 domain; Region: SH3_3; pfam08239
1087448006334	3D domain; Region: 3D; cl01439
1087448006335	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
1087448006336	Helix-turn-helix domain; Region: HTH_38; pfam13936
1087448006337	Integrase core domain; Region: rve; pfam00665
1087448006338	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
1087448006339	propionate/acetate kinase; Provisional; Region: PRK12379
1087448006340	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0827
1087448006341	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1087448006342	S-adenosylmethionine binding site [chemical binding]; other site
1087448006343	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
1087448006344	dimer interface [polypeptide binding]; other site
1087448006345	catalytic triad [active]
1087448006346	peroxidatic and resolving cysteines [active]
1087448006347	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03501
1087448006348	ATP-NAD kinase; Region: NAD_kinase; pfam01513
1087448006349	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
1087448006350	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
1087448006351	active site
1087448006352	Septation ring formation regulator, EzrA; Region: EzrA; pfam06160
1087448006353	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
1087448006354	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1087448006355	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1087448006356	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1087448006357	RNA binding surface [nucleotide binding]; other site
1087448006358	BioY family; Region: BioY; pfam02632
1087448006359	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1087448006360	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1087448006361	active site
1087448006362	HIGH motif; other site
1087448006363	dimer interface [polypeptide binding]; other site
1087448006364	KMSKS motif; other site
1087448006365	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1087448006366	RNA binding surface [nucleotide binding]; other site
1087448006367	Transglycosylase; Region: Transgly; pfam00912
1087448006368	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
1087448006369	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1087448006370	acetyl-CoA synthetase; Provisional; Region: PRK04319
1087448006371	Domain of unknown function (DUF3448); Region: DUF3448; pfam11930
1087448006372	Uncharacterized subfamily of Acetyl-CoA synthetase like family (ACS); Region: MACS_like_4; cd05969
1087448006373	active site
1087448006374	acyl-activating enzyme (AAE) consensus motif; other site
1087448006375	putative CoA binding site [chemical binding]; other site
1087448006376	AMP binding site [chemical binding]; other site
1087448006377	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1087448006378	Coenzyme A binding pocket [chemical binding]; other site
1087448006379	FOG: CBS domain [General function prediction only]; Region: COG0517
1087448006380	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in  the acetoin utilization proteins in bacteria. Acetoin is a product of fermentative metabolism in many prokaryotic and eukaryotic microorganisms.  They produce...; Region: CBS_pair_ACT_assoc; cd04584
1087448006381	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1087448006382	Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcuC; COG0123
1087448006383	Class I histone deacetylase AcuC (Acetoin utilization protein)-like enzymes; Region: HDAC_AcuC_like; cd09994
1087448006384	active site
1087448006385	Zn binding site [ion binding]; other site
1087448006386	catabolite control protein A; Region: ccpA; TIGR01481
1087448006387	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1087448006388	DNA binding site [nucleotide binding]
1087448006389	domain linker motif; other site
1087448006390	Ligand-binding domain of the catabolite control protein A (CcpA), which functions as the major transcriptional regulator of carbon catabolite repression/regulation; Region: PBP1_CcpA_like; cd06298
1087448006391	dimerization interface [polypeptide binding]; other site
1087448006392	effector binding site; other site
1087448006393	bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase; Reviewed; Region: PRK12595
1087448006394	Chorismate mutase type II; Region: CM_2; cl00693
1087448006395	phospho-2-dehydro-3-deoxyheptonate aldolase; Region: DAHP_synth_Bsub; TIGR01361
1087448006396	Bacterial protein of unknown function (DUF948); Region: DUF948; pfam06103
1087448006397	Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309
1087448006398	Thermophilic metalloprotease (M29); Region: Peptidase_M29; pfam02073
1087448006399	Ferritin-like domain; Region: Ferritin; pfam00210
1087448006400	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1087448006401	dimerization interface [polypeptide binding]; other site
1087448006402	DPS ferroxidase diiron center [ion binding]; other site
1087448006403	ion pore; other site
1087448006404	hypothetical protein; Provisional; Region: PRK04164
1087448006405	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1087448006406	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1087448006407	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1087448006408	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1087448006409	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1087448006410	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1087448006411	putative tRNA-binding site [nucleotide binding]; other site
1087448006412	hypothetical protein; Provisional; Region: PRK13668
1087448006413	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1087448006414	catalytic residues [active]
1087448006415	Predicted membrane protein, putative toxin regulator [General function prediction only]; Region: PfoR; COG3641
1087448006416	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
1087448006417	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
1087448006418	oligomer interface [polypeptide binding]; other site
1087448006419	active site
1087448006420	metal binding site [ion binding]; metal-binding site
1087448006421	Predicted small secreted protein [Function unknown]; Region: COG5584
1087448006422	Protein of unknown function (DUF1304); Region: DUF1304; pfam06993
1087448006423	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1087448006424	S-adenosylmethionine binding site [chemical binding]; other site
1087448006425	acetolactate synthase; Reviewed; Region: PRK08617
1087448006426	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1087448006427	PYR/PP interface [polypeptide binding]; other site
1087448006428	dimer interface [polypeptide binding]; other site
1087448006429	TPP binding site [chemical binding]; other site
1087448006430	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1087448006431	Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; composed of proteins similar to Klebsiella pneumoniae ALS, a catabolic enzyme required for butanediol fermentation. ALS catalyzes the conversion of 2...; Region: TPP_ALS; cd02010
1087448006432	TPP-binding site [chemical binding]; other site
1087448006433	dimer interface [polypeptide binding]; other site
1087448006434	Alpha-acetolactate decarboxylase; Region: AAL_decarboxy; pfam03306
1087448006435	Phosphotransferase enzyme family; Region: APH; pfam01636
1087448006436	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1087448006437	active site
1087448006438	substrate binding site [chemical binding]; other site
1087448006439	ATP binding site [chemical binding]; other site
1087448006440	pullulanase, type I; Region: pulA_typeI; TIGR02104
1087448006441	Early set domain associated with the catalytic domain of pullulanase (also called dextrinase and alpha-dextrin endo-1,6-alpha glucosidase); Region: E_set_Pullulanase; cd02860
1087448006442	Alpha amylase catalytic domain found in Pullulanase (also called dextrinase; alpha-dextrin endo-1,6-alpha glucosidase), limit dextrinase, and related proteins; Region: AmyAc_Pullulanase_LD-like; cd11341
1087448006443	Ca binding site [ion binding]; other site
1087448006444	active site
1087448006445	catalytic site [active]
1087448006446	2'-5' RNA ligase; Region: 2_5_ligase; TIGR02258
1087448006447	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1087448006448	sugar efflux transporter; Region: 2A0120; TIGR00899
1087448006449	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1087448006450	putative substrate translocation pore; other site
1087448006451	dipeptidase PepV; Reviewed; Region: PRK07318
1087448006452	M20 Peptidase Xaa-His dipeptidase (PepV) degrades hydrophobic dipeptides; Region: M20_PepV; cd03888
1087448006453	active site
1087448006454	metal binding site [ion binding]; metal-binding site
1087448006455	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
1087448006456	atypical (a) SDRs, subgroup 5; Region: SDR_a5; cd05243
1087448006457	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1087448006458	NAD(P) binding site [chemical binding]; other site
1087448006459	putative active site [active]
1087448006460	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1087448006461	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1087448006462	RNA binding surface [nucleotide binding]; other site
1087448006463	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
1087448006464	active site
1087448006465	uracil binding [chemical binding]; other site
1087448006466	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1087448006467	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
1087448006468	HI0933-like protein; Region: HI0933_like; pfam03486
1087448006469	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
1087448006470	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1087448006471	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1087448006472	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1087448006473	HIGH motif; other site
1087448006474	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1087448006475	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1087448006476	active site
1087448006477	KMSKS motif; other site
1087448006478	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1087448006479	tRNA binding surface [nucleotide binding]; other site
1087448006480	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
1087448006481	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1087448006482	motif II; other site
1087448006483	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1087448006484	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1087448006485	putative substrate translocation pore; other site
1087448006486	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1087448006487	Putative rRNA methylase; Region: rRNA_methylase; pfam06962
1087448006488	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1087448006489	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
1087448006490	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1087448006491	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1087448006492	Coenzyme A binding pocket [chemical binding]; other site
1087448006493	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1087448006494	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1087448006495	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1087448006496	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1087448006497	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
1087448006498	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
1087448006499	active site
1087448006500	substrate-binding site [chemical binding]; other site
1087448006501	metal-binding site [ion binding]
1087448006502	ATP binding site [chemical binding]; other site
1087448006503	Predicted signal transduction protein containing EAL and modified HD-GYP domains [Signal transduction mechanisms]; Region: COG3434
1087448006504	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1087448006505	nucleoside triphosphatase YtkD; Region: nudix_YtkD; TIGR02705
1087448006506	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_8; cd04665
1087448006507	nudix motif; other site
1087448006508	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
1087448006509	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1087448006510	active site
1087448006511	dimer interface [polypeptide binding]; other site
1087448006512	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1087448006513	dimer interface [polypeptide binding]; other site
1087448006514	active site
1087448006515	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
1087448006516	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
1087448006517	dimer interface [polypeptide binding]; other site
1087448006518	active site
1087448006519	metal binding site [ion binding]; metal-binding site
1087448006520	general stress protein 13; Validated; Region: PRK08059
1087448006521	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
1087448006522	RNA binding site [nucleotide binding]; other site
1087448006523	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1087448006524	diiron center [ion binding]; other site
1087448006525	putative radical transfer pathway; other site
1087448006526	dimer interface [polypeptide binding]; other site
1087448006527	tyrosyl radical; other site
1087448006528	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1087448006529	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09209
1087448006530	Ribonucleotide reductase, all-alpha domain; Region: Ribonuc_red_lgN; pfam00317
1087448006531	Ribonucleotide reductase, barrel domain; Region: Ribonuc_red_lgC; pfam02867
1087448006532	Domain of unknown function (DUF1871); Region: DUF1871; pfam08958
1087448006533	Scaffold protein Nfu/NifU N terminal; Region: Nfu_N; cl07364
1087448006534	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1087448006535	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1087448006536	active site
1087448006537	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1087448006538	AsnC family; Region: AsnC_trans_reg; pfam01037
1087448006539	hypothetical protein; Validated; Region: PRK07682
1087448006540	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1087448006541	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1087448006542	homodimer interface [polypeptide binding]; other site
1087448006543	catalytic residue [active]
1087448006544	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain superfamily; Region: NTP-PPase; cl16941
1087448006545	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain superfamily; Region: NTP-PPase; cl16941
1087448006546	metal binding site [ion binding]; metal-binding site
1087448006547	Vpu protein; Region: Vpu; pfam00558
1087448006548	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
1087448006549	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1087448006550	Protein of unknown function (DUF429); Region: DUF429; cl12046
1087448006551	multifunctional aminopeptidase A; Provisional; Region: PRK00913
1087448006552	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1087448006553	interface (dimer of trimers) [polypeptide binding]; other site
1087448006554	Substrate-binding/catalytic site; other site
1087448006555	Zn-binding sites [ion binding]; other site
1087448006556	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
1087448006557	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1087448006558	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1087448006559	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1087448006560	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1087448006561	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1087448006562	putative substrate translocation pore; other site
1087448006563	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1087448006564	PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002
1087448006565	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1087448006566	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1087448006567	active site turn [active]
1087448006568	phosphorylation site [posttranslational modification]
1087448006569	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1087448006570	HPr interaction site; other site
1087448006571	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1087448006572	active site
1087448006573	phosphorylation site [posttranslational modification]
1087448006574	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1087448006575	PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002
1087448006576	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1087448006577	active site turn [active]
1087448006578	phosphorylation site [posttranslational modification]
1087448006579	CAT RNA binding domain; Region: CAT_RBD; smart01061
1087448006580	transcriptional antiterminator BglG; Provisional; Region: PRK09772
1087448006581	PRD domain; Region: PRD; pfam00874
1087448006582	PRD domain; Region: PRD; pfam00874
1087448006583	Putative membrane protein; Region: YuiB; pfam14068
1087448006584	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
1087448006585	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1087448006586	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
1087448006587	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1087448006588	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1087448006589	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1087448006590	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1087448006591	Coenzyme A binding pocket [chemical binding]; other site
1087448006592	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1087448006593	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1087448006594	NAD(P) binding site [chemical binding]; other site
1087448006595	active site
1087448006596	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
1087448006597	Predicted membrane protein [Function unknown]; Region: COG3601
1087448006598	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
1087448006599	hypothetical protein; Provisional; Region: PRK13669
1087448006600	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
1087448006601	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1087448006602	Protein of unknown function (DUF1462); Region: DUF1462; cl11552
1087448006603	NifU-like domain; Region: NifU; cl00484
1087448006604	HAD-superfamily subfamily IIA hydrolase, TIGR01457; Region: HAD-SF-IIA-hyp2
1087448006605	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1087448006606	active site
1087448006607	motif I; other site
1087448006608	motif II; other site
1087448006609	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1087448006610	Uncharacterized conserved protein [Function unknown]; Region: COG2445
1087448006611	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
1087448006612	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
1087448006613	putative active site [active]
1087448006614	Protein of unknown function (DUF3055); Region: DUF3055; pfam11256
1087448006615	Heat induced stress protein YflT; Region: YflT; pfam11181
1087448006616	Protein of unknown function (DUF1027); Region: DUF1027; pfam06265
1087448006617	lipoyl synthase; Provisional; Region: PRK05481
1087448006618	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1087448006619	FeS/SAM binding site; other site
1087448006620	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
1087448006621	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
1087448006622	active site
1087448006623	metal binding site [ion binding]; metal-binding site
1087448006624	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1087448006625	Protein of unknown function DUF72; Region: DUF72; pfam01904
1087448006626	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1087448006627	RibD C-terminal domain; Region: RibD_C; cl17279
1087448006628	FeS assembly protein SufB; Region: sufB; TIGR01980
1087448006629	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814; cl03223
1087448006630	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
1087448006631	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1087448006632	trimerization site [polypeptide binding]; other site
1087448006633	active site
1087448006634	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1087448006635	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1087448006636	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1087448006637	catalytic residue [active]
1087448006638	Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]; Region: SufB; COG0719
1087448006639	FeS assembly protein SufD; Region: sufD; TIGR01981
1087448006640	Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones]; Region: sufC; COG0396
1087448006641	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
1087448006642	Walker A/P-loop; other site
1087448006643	ATP binding site [chemical binding]; other site
1087448006644	Q-loop/lid; other site
1087448006645	ABC transporter signature motif; other site
1087448006646	Walker B; other site
1087448006647	D-loop; other site
1087448006648	H-loop/switch region; other site
1087448006649	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1087448006650	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1087448006651	putative substrate translocation pore; other site
1087448006652	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1087448006653	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1087448006654	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1087448006655	dimer interface [polypeptide binding]; other site
1087448006656	conserved gate region; other site
1087448006657	ABC-ATPase subunit interface; other site
1087448006658	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
1087448006659	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1087448006660	Walker A/P-loop; other site
1087448006661	ATP binding site [chemical binding]; other site
1087448006662	Q-loop/lid; other site
1087448006663	ABC transporter signature motif; other site
1087448006664	Walker B; other site
1087448006665	D-loop; other site
1087448006666	H-loop/switch region; other site
1087448006667	NIL domain; Region: NIL; pfam09383
1087448006668	cystathionine beta-lyase; Provisional; Region: PRK07671
1087448006669	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1087448006670	homodimer interface [polypeptide binding]; other site
1087448006671	substrate-cofactor binding pocket; other site
1087448006672	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1087448006673	catalytic residue [active]
1087448006674	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1087448006675	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1087448006676	dimer interface [polypeptide binding]; other site
1087448006677	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1087448006678	catalytic residue [active]
1087448006679	S-ribosylhomocysteinase; Provisional; Region: PRK02260
1087448006680	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1087448006681	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1087448006682	S-adenosylmethionine binding site [chemical binding]; other site
1087448006683	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1087448006684	catalytic residues [active]
1087448006685	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
1087448006686	lipoyl attachment site [posttranslational modification]; other site
1087448006687	Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX)...; Region: ArsC_like; cd03036
1087448006688	ArsC family; Region: ArsC; pfam03960
1087448006689	putative ArsC-like catalytic residues; other site
1087448006690	putative TRX-like catalytic residues [active]
1087448006691	DinB superfamily; Region: DinB_2; pfam12867
1087448006692	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1087448006693	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
1087448006694	active site
1087448006695	acetyl-CoA acetyltransferase; Provisional; Region: PRK07661
1087448006696	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1087448006697	dimer interface [polypeptide binding]; other site
1087448006698	active site
1087448006699	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1087448006700	3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Region: FadB; COG1250
1087448006701	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1087448006702	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1087448006703	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1087448006704	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
1087448006705	substrate binding site [chemical binding]; other site
1087448006706	oxyanion hole (OAH) forming residues; other site
1087448006707	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1087448006708	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1087448006709	S-adenosylmethionine binding site [chemical binding]; other site
1087448006710	Proline dehydrogenase; Region: Pro_dh; cl03282
1087448006711	Uncharacterized conserved protein [Function unknown]; Region: COG0398
1087448006712	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1087448006713	Haemolysin-III related; Region: HlyIII; cl03831
1087448006714	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
1087448006715	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
1087448006716	metal binding site [ion binding]; metal-binding site
1087448006717	phosphoribosyl-AMP cyclohydrolase; Reviewed; Region: hisI; PRK00051
1087448006718	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
1087448006719	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1087448006720	substrate binding site [chemical binding]; other site
1087448006721	glutamase interaction surface [polypeptide binding]; other site
1087448006722	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
1087448006723	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
1087448006724	catalytic residues [active]
1087448006725	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13141
1087448006726	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
1087448006727	putative active site [active]
1087448006728	oxyanion strand; other site
1087448006729	catalytic triad [active]
1087448006730	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
1087448006731	putative active site pocket [active]
1087448006732	4-fold oligomerization interface [polypeptide binding]; other site
1087448006733	metal binding residues [ion binding]; metal-binding site
1087448006734	3-fold/trimer interface [polypeptide binding]; other site
1087448006735	Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism]; Region: HisC; COG0079
1087448006736	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1087448006737	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1087448006738	homodimer interface [polypeptide binding]; other site
1087448006739	catalytic residue [active]
1087448006740	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
1087448006741	histidinol dehydrogenase; Region: hisD; TIGR00069
1087448006742	NAD binding site [chemical binding]; other site
1087448006743	dimerization interface [polypeptide binding]; other site
1087448006744	product binding site; other site
1087448006745	substrate binding site [chemical binding]; other site
1087448006746	zinc binding site [ion binding]; other site
1087448006747	catalytic residues [active]
1087448006748	ATP phosphoribosyltransferase; Region: HisG; cl15266
1087448006749	ATP phosphoribosyltransferase [Amino acid transport and metabolism]; Region: HisG; COG0040
1087448006750	Histidyl-tRNA synthetase; Region: tRNA-synt_His; pfam13393
1087448006751	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1087448006752	motif 1; other site
1087448006753	dimer interface [polypeptide binding]; other site
1087448006754	active site
1087448006755	motif 2; other site
1087448006756	motif 3; other site
1087448006757	histidinol-phosphatase; Reviewed; Region: PRK08123
1087448006758	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase of Hisj like; Region: PHP_HisPPase_Hisj_like; cd12110
1087448006759	active site
1087448006760	dimer interface [polypeptide binding]; other site
1087448006761	Hexulose-6-phosphate isomerase (PHI). PHI is a member of the SIS (Sugar ISomerase domain) superfamily. In the ribulose monophosphate pathway of formaldehyde fixation, hexulose-6-phosphate synthase catalyzes the condensation of ribulose-5-phosphate with...; Region: SIS_PHI; cd05005
1087448006762	tetramer interface [polypeptide binding]; other site
1087448006763	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1087448006764	active site
1087448006765	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
1087448006766	active site
1087448006767	dimer interface [polypeptide binding]; other site
1087448006768	magnesium binding site [ion binding]; other site
1087448006769	Predicted transcriptional regulators [Transcription]; Region: COG1733
1087448006770	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1087448006771	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1087448006772	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1087448006773	Coenzyme A binding pocket [chemical binding]; other site
1087448006774	AAA ATPase domain; Region: AAA_15; pfam13175
1087448006775	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
1087448006776	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
1087448006777	putative active site [active]
1087448006778	putative metal-binding site [ion binding]; other site
1087448006779	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1087448006780	SmpB-tmRNA interface; other site
1087448006781	ribonuclease R; Region: RNase_R; TIGR02063
1087448006782	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1087448006783	RNB domain; Region: RNB; pfam00773
1087448006784	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
1087448006785	RNA binding site [nucleotide binding]; other site
1087448006786	Esterase/lipase [General function prediction only]; Region: COG1647
1087448006787	Uncharacterized protein family (UPF0227); Region: UPF0227; cl14886
1087448006788	Uncharacterized conserved protein (DUF2048); Region: DUF2048; pfam09752
1087448006789	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
1087448006790	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
1087448006791	ligand binding site [chemical binding]; other site
1087448006792	dimerization interface [polypeptide binding]; other site
1087448006793	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1087448006794	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1087448006795	TM-ABC transporter signature motif; other site
1087448006796	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
1087448006797	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
1087448006798	Walker A/P-loop; other site
1087448006799	ATP binding site [chemical binding]; other site
1087448006800	Q-loop/lid; other site
1087448006801	ABC transporter signature motif; other site
1087448006802	Walker B; other site
1087448006803	D-loop; other site
1087448006804	H-loop/switch region; other site
1087448006805	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
1087448006806	D-ribose pyranase; Provisional; Region: PRK11797
1087448006807	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1087448006808	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1087448006809	substrate binding site [chemical binding]; other site
1087448006810	dimer interface [polypeptide binding]; other site
1087448006811	ATP binding site [chemical binding]; other site
1087448006812	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1087448006813	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1087448006814	DNA binding site [nucleotide binding]
1087448006815	domain linker motif; other site
1087448006816	Ligand binding domain of the lacI-like transcription regulator from a novel metal-reducing bacterium Alkaliphilus Metalliredigens (strain Qymf) and its close homologs; Region: PBP1_Qymf_like; cd06291
1087448006817	dimerization interface [polypeptide binding]; other site
1087448006818	ligand binding site [chemical binding]; other site
1087448006819	sodium binding site [ion binding]; other site
1087448006820	Acyl ACP desaturase, ferritin-like diiron-binding domain; Region: Acyl_ACP_Desat; cd01050
1087448006821	Fatty acid desaturase; Region: FA_desaturase_2; pfam03405
1087448006822	homodimer interface [polypeptide binding]; other site
1087448006823	putative substrate binding pocket [chemical binding]; other site
1087448006824	diiron center [ion binding]; other site
1087448006825	enolase; Provisional; Region: eno; PRK00077
1087448006826	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1087448006827	dimer interface [polypeptide binding]; other site
1087448006828	metal binding site [ion binding]; metal-binding site
1087448006829	substrate binding pocket [chemical binding]; other site
1087448006830	Phosphoglyceromutase [Carbohydrate transport and metabolism]; Region: GpmI; COG0696
1087448006831	phosphoglyceromutase; Provisional; Region: PRK05434
1087448006832	triosephosphate isomerase; Provisional; Region: PRK14567
1087448006833	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1087448006834	substrate binding site [chemical binding]; other site
1087448006835	dimer interface [polypeptide binding]; other site
1087448006836	catalytic triad [active]
1087448006837	Phosphoglycerate kinase; Region: PGK; pfam00162
1087448006838	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
1087448006839	substrate binding site [chemical binding]; other site
1087448006840	hinge regions; other site
1087448006841	ADP binding site [chemical binding]; other site
1087448006842	catalytic site [active]
1087448006843	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
1087448006844	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1087448006845	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1087448006846	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
1087448006847	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
1087448006848	Glutaredoxin-like domain (DUF836); Region: DUF836; pfam05768
1087448006849	RNA polymerase sigma-54 factor; Region: rpoN_sigma; TIGR02395
1087448006850	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
1087448006851	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
1087448006852	Clp protease; Region: CLP_protease; pfam00574
1087448006853	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1087448006854	oligomer interface [polypeptide binding]; other site
1087448006855	active site residues [active]
1087448006856	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1481
1087448006857	Sporulation Regulator WhiA N terminal; Region: WhiA_N; pfam10298
1087448006858	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
1087448006859	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
1087448006860	phosphate binding site [ion binding]; other site
1087448006861	putative substrate binding pocket [chemical binding]; other site
1087448006862	dimer interface [polypeptide binding]; other site
1087448006863	glmZ(sRNA)-inactivating NTPase; Provisional; Region: PRK05416
1087448006864	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
1087448006865	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1087448006866	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1087448006867	Kinase associated protein B; Region: KapB; pfam08810
1087448006868	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
1087448006869	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
1087448006870	trimer interface [polypeptide binding]; other site
1087448006871	active site
1087448006872	substrate binding site [chemical binding]; other site
1087448006873	CoA binding site [chemical binding]; other site
1087448006874	pyrophosphatase PpaX; Provisional; Region: PRK13288
1087448006875	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1087448006876	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1087448006877	motif II; other site
1087448006878	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK12437
1087448006879	HPr kinase/phosphorylase; Provisional; Region: PRK05428
1087448006880	HPr Serine kinase N terminus; Region: Hpr_kinase_N; pfam02603
1087448006881	HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918
1087448006882	Hpr binding site; other site
1087448006883	active site
1087448006884	homohexamer subunit interaction site [polypeptide binding]; other site
1087448006885	Uncharacterized conserved protein [Function unknown]; Region: COG3595
1087448006886	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
1087448006887	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1087448006888	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1087448006889	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1087448006890	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1087448006891	excinuclease ABC subunit B; Provisional; Region: PRK05298
1087448006892	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1087448006893	ATP binding site [chemical binding]; other site
1087448006894	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1087448006895	nucleotide binding region [chemical binding]; other site
1087448006896	ATP-binding site [chemical binding]; other site
1087448006897	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1087448006898	UvrB/uvrC motif; Region: UVR; pfam02151
1087448006899	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1087448006900	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
1087448006901	C-terminal peptidase (prc); Region: prc; TIGR00225
1087448006902	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1087448006903	protein binding site [polypeptide binding]; other site
1087448006904	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1087448006905	Catalytic dyad [active]
1087448006906	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1087448006907	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
1087448006908	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1087448006909	Peptidase family M23; Region: Peptidase_M23; pfam01551
1087448006910	Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177
1087448006911	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
1087448006912	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
1087448006913	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1087448006914	Walker A/P-loop; other site
1087448006915	ATP binding site [chemical binding]; other site
1087448006916	Q-loop/lid; other site
1087448006917	ABC transporter signature motif; other site
1087448006918	Walker B; other site
1087448006919	D-loop; other site
1087448006920	H-loop/switch region; other site
1087448006921	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
1087448006922	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
1087448006923	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1087448006924	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1087448006925	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1087448006926	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1087448006927	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1087448006928	Coenzyme A binding pocket [chemical binding]; other site
1087448006929	peptide chain release factor 2; Validated; Region: prfB; PRK00578
1087448006930	PCRF domain; Region: PCRF; pfam03462
1087448006931	RF-1 domain; Region: RF-1; pfam00472
1087448006932	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1087448006933	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1087448006934	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1087448006935	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
1087448006936	nucleotide binding region [chemical binding]; other site
1087448006937	ATP-binding site [chemical binding]; other site
1087448006938	SEC-C motif; Region: SEC-C; pfam02810
1087448006939	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1087448006940	30S subunit binding site; other site
1087448006941	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1087448006942	DNA-binding site [nucleotide binding]; DNA binding site
1087448006943	RNA-binding motif; other site
1087448006944	ComK protein; Region: ComK; pfam06338
1087448006945	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
1087448006946	Flagellar protein FliS; Region: FliS; cl00654
1087448006947	flagellin; Provisional; Region: PRK12804
1087448006948	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1087448006949	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1087448006950	Protein of unknown function (DUF327); Region: DUF327; pfam03885
1087448006951	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1655
1087448006952	Uncharacterized protein conserved in bacteria (DUF2225); Region: DUF2225; pfam09986
1087448006953	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1087448006954	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1087448006955	metal binding site [ion binding]; metal-binding site
1087448006956	active site
1087448006957	I-site; other site
1087448006958	Flagellar protein FliS; Region: FliS; cl00654
1087448006959	flagellar capping protein; Validated; Region: fliD; PRK07737
1087448006960	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
1087448006961	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
1087448006962	FlaG protein; Region: FlaG; cl00591
1087448006963	LAGLIDADG DNA endonuclease family; Region: LAGLIDADG_2; pfam03161
1087448006964	flagellin; Provisional; Region: PRK12806
1087448006965	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1087448006966	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1087448006967	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1087448006968	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1087448006969	dimer interface [polypeptide binding]; other site
1087448006970	putative CheW interface [polypeptide binding]; other site
1087448006971	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1087448006972	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1087448006973	peptide binding site [polypeptide binding]; other site
1087448006974	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1087448006975	Coenzyme A binding pocket [chemical binding]; other site
1087448006976	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1087448006977	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1087448006978	Coenzyme A binding pocket [chemical binding]; other site
1087448006979	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1087448006980	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1087448006981	dimerization interface [polypeptide binding]; other site
1087448006982	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1087448006983	dimer interface [polypeptide binding]; other site
1087448006984	phosphorylation site [posttranslational modification]
1087448006985	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1087448006986	ATP binding site [chemical binding]; other site
1087448006987	Mg2+ binding site [ion binding]; other site
1087448006988	G-X-G motif; other site
1087448006989	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1087448006990	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1087448006991	active site
1087448006992	phosphorylation site [posttranslational modification]
1087448006993	intermolecular recognition site; other site
1087448006994	dimerization interface [polypeptide binding]; other site
1087448006995	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1087448006996	DNA binding site [nucleotide binding]
1087448006997	PAS domain S-box; Region: sensory_box; TIGR00229
1087448006998	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1087448006999	putative active site [active]
1087448007000	heme pocket [chemical binding]; other site
1087448007001	PAS domain S-box; Region: sensory_box; TIGR00229
1087448007002	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1087448007003	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1087448007004	metal binding site [ion binding]; metal-binding site
1087448007005	active site
1087448007006	I-site; other site
1087448007007	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1087448007008	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1087448007009	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1087448007010	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1087448007011	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1087448007012	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1087448007013	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1087448007014	Squalene/phytoene synthase; Region: SQS_PSY; pfam00494
1087448007015	substrate binding pocket [chemical binding]; other site
1087448007016	substrate-Mg2+ binding site; other site
1087448007017	aspartate-rich region 1; other site
1087448007018	aspartate-rich region 2; other site
1087448007019	carbon storage regulator; Provisional; Region: PRK01712
1087448007020	FliW protein; Region: FliW; cl00740
1087448007021	flagellar hook-associated protein FlgL; Validated; Region: flgL; PRK07701
1087448007022	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1087448007023	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1087448007024	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK07739
1087448007025	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1087448007026	FlgN protein; Region: FlgN; pfam05130
1087448007027	Anti-sigma-28 factor, FlgM; Region: FlgM; pfam04316
1087448007028	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
1087448007029	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1087448007030	active site
1087448007031	EDD domain protein, DegV family; Region: DegV; TIGR00762
1087448007032	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
1087448007033	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1087448007034	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1087448007035	active site
1087448007036	phosphorylation site [posttranslational modification]
1087448007037	intermolecular recognition site; other site
1087448007038	dimerization interface [polypeptide binding]; other site
1087448007039	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1087448007040	DNA binding residues [nucleotide binding]
1087448007041	dimerization interface [polypeptide binding]; other site
1087448007042	Sensor protein DegS; Region: DegS; pfam05384
1087448007043	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
1087448007044	Histidine kinase; Region: HisKA_3; pfam07730
1087448007045	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1087448007046	ATP binding site [chemical binding]; other site
1087448007047	Mg2+ binding site [ion binding]; other site
1087448007048	G-X-G motif; other site
1087448007049	uncharacterized protein, YigZ family; Region: IMPACT_YIGZ; TIGR00257
1087448007050	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
1087448007051	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
1087448007052	Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; cl00581
1087448007053	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1087448007054	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1087448007055	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1087448007056	Coenzyme A binding pocket [chemical binding]; other site
1087448007057	Chromate transport protein ChrA [Inorganic ion transport and metabolism]; Region: ChrA; COG2059
1087448007058	chromate transporter, chromate ion transporter (CHR) family; Region: 2A51; TIGR00937
1087448007059	Chromate transporter; Region: Chromate_transp; pfam02417
1087448007060	Predicted membrane protein [Function unknown]; Region: COG2311
1087448007061	Protein of unknown function (DUF418); Region: DUF418; cl12135
1087448007062	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
1087448007063	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
1087448007064	Mg++ binding site [ion binding]; other site
1087448007065	putative catalytic motif [active]
1087448007066	substrate binding site [chemical binding]; other site
1087448007067	Bacterial SH3 domain; Region: SH3_3; pfam08239
1087448007068	Bacterial SH3 domain; Region: SH3_3; pfam08239
1087448007069	Bacterial SH3 domain; Region: SH3_3; pfam08239
1087448007070	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1087448007071	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1087448007072	active site
1087448007073	metal binding site [ion binding]; metal-binding site
1087448007074	beta-phosphoglucomutase; Region: bPGM; TIGR01990
1087448007075	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1087448007076	motif II; other site
1087448007077	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1087448007078	SecA preprotein cross-linking domain; Region: SecA_PP_bind; pfam01043
1087448007079	nucleotide binding region [chemical binding]; other site
1087448007080	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1087448007081	ATP-binding site [chemical binding]; other site
1087448007082	Asp23 family; Region: Asp23; pfam03780
1087448007083	Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism]; Region: NolL; COG3594
1087448007084	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1087448007085	sialate_O-acetylesterase_like subfamily of the SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: sialate_O-acetylesterase_like2; cd01828
1087448007086	active site
1087448007087	catalytic triad [active]
1087448007088	oxyanion hole [active]
1087448007089	Predicted esterase [General function prediction only]; Region: COG0400
1087448007090	putative hydrolase; Provisional; Region: PRK11460
1087448007091	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4152
1087448007092	ATP-binding cassette domain of an uncharacterized transporter; Region: ABC_putative_ATPase; cd03269
1087448007093	Walker A/P-loop; other site
1087448007094	ATP binding site [chemical binding]; other site
1087448007095	Q-loop/lid; other site
1087448007096	ABC transporter signature motif; other site
1087448007097	Walker B; other site
1087448007098	D-loop; other site
1087448007099	H-loop/switch region; other site
1087448007100	Domain of unknown function (DUF4162); Region: DUF4162; pfam13732
1087448007101	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
1087448007102	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1087448007103	non-specific DNA binding site [nucleotide binding]; other site
1087448007104	salt bridge; other site
1087448007105	sequence-specific DNA binding site [nucleotide binding]; other site
1087448007106	FtsX-like permease family; Region: FtsX; pfam02687
1087448007107	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1087448007108	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1087448007109	Walker A/P-loop; other site
1087448007110	ATP binding site [chemical binding]; other site
1087448007111	Q-loop/lid; other site
1087448007112	ABC transporter signature motif; other site
1087448007113	Walker B; other site
1087448007114	D-loop; other site
1087448007115	H-loop/switch region; other site
1087448007116	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1087448007117	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
1087448007118	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1087448007119	ATP binding site [chemical binding]; other site
1087448007120	Mg2+ binding site [ion binding]; other site
1087448007121	G-X-G motif; other site
1087448007122	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1087448007123	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1087448007124	active site
1087448007125	phosphorylation site [posttranslational modification]
1087448007126	intermolecular recognition site; other site
1087448007127	dimerization interface [polypeptide binding]; other site
1087448007128	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1087448007129	DNA binding site [nucleotide binding]
1087448007130	FtsX-like permease family; Region: FtsX; pfam02687
1087448007131	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1087448007132	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1087448007133	Walker A/P-loop; other site
1087448007134	ATP binding site [chemical binding]; other site
1087448007135	Q-loop/lid; other site
1087448007136	ABC transporter signature motif; other site
1087448007137	Walker B; other site
1087448007138	D-loop; other site
1087448007139	H-loop/switch region; other site
1087448007140	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
1087448007141	HPr interaction site; other site
1087448007142	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1087448007143	active site
1087448007144	phosphorylation site [posttranslational modification]
1087448007145	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_1; cd09606
1087448007146	oligoendopeptidase, M3 family; Region: M3_not_pepF; TIGR02289
1087448007147	active site
1087448007148	Zn binding site [ion binding]; other site
1087448007149	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1087448007150	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1087448007151	metal binding site [ion binding]; metal-binding site
1087448007152	active site
1087448007153	I-site; other site
1087448007154	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1087448007155	FOG: CBS domain [General function prediction only]; Region: COG0517
1087448007156	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_30; cd04643
1087448007157	Cache domain; Region: Cache_1; pfam02743
1087448007158	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1087448007159	dimerization interface [polypeptide binding]; other site
1087448007160	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1087448007161	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1087448007162	dimer interface [polypeptide binding]; other site
1087448007163	putative CheW interface [polypeptide binding]; other site
1087448007164	YSIRK-targeted surface antigen transcriptional regulator; Region: adjacent_YSIRK; TIGR04094
1087448007165	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1087448007166	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
1087448007167	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Region: Glyphos_transf; pfam04464
1087448007168	Predicted RNA-binding protein, contains TRAM domain [General function prediction only]; Region: COG3269
1087448007169	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
1087448007170	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1087448007171	S-adenosylmethionine binding site [chemical binding]; other site
1087448007172	putative lipid kinase; Reviewed; Region: PRK13337
1087448007173	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1087448007174	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
1087448007175	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
1087448007176	GatB domain; Region: GatB_Yqey; smart00845
1087448007177	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
1087448007178	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
1087448007179	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
1087448007180	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1087448007181	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
1087448007182	Na binding site [ion binding]; other site
1087448007183	1-pyrroline-5-carboxylate dehydrogenase; Provisional; Region: PRK03137
1087448007184	Delta(1)-pyrroline-5-carboxylate dehydrogenase, RocA; Region: ALDH_PutA-P5CDH-RocA; cd07124
1087448007185	Glutamate binding site [chemical binding]; other site
1087448007186	homodimer interface [polypeptide binding]; other site
1087448007187	NAD binding site [chemical binding]; other site
1087448007188	catalytic residues [active]
1087448007189	Iron-sulphur cluster biosynthesis; Region: Fe-S_biosyn; cl00400
1087448007190	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1087448007191	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1087448007192	catalytic triad [active]
1087448007193	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1087448007194	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1087448007195	peptide binding site [polypeptide binding]; other site
1087448007196	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1087448007197	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1087448007198	metal binding site [ion binding]; metal-binding site
1087448007199	active site
1087448007200	I-site; other site
1087448007201	Protein of unknown function (DUF1054); Region: DUF1054; pfam06335
1087448007202	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
1087448007203	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1087448007204	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
1087448007205	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1087448007206	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1087448007207	dimer interface [polypeptide binding]; other site
1087448007208	conserved gate region; other site
1087448007209	putative PBP binding loops; other site
1087448007210	ABC-ATPase subunit interface; other site
1087448007211	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1087448007212	dimer interface [polypeptide binding]; other site
1087448007213	conserved gate region; other site
1087448007214	putative PBP binding loops; other site
1087448007215	ABC-ATPase subunit interface; other site
1087448007216	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1087448007217	ATP-binding cassette domain of the polyamine transporter; Region: ABC_PotA_N; cd03300
1087448007218	Walker A/P-loop; other site
1087448007219	ATP binding site [chemical binding]; other site
1087448007220	Q-loop/lid; other site
1087448007221	ABC transporter signature motif; other site
1087448007222	Walker B; other site
1087448007223	D-loop; other site
1087448007224	H-loop/switch region; other site
1087448007225	TOBE domain; Region: TOBE_2; pfam08402
1087448007226	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1087448007227	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1087448007228	non-specific DNA binding site [nucleotide binding]; other site
1087448007229	salt bridge; other site
1087448007230	sequence-specific DNA binding site [nucleotide binding]; other site
1087448007231	Cupin domain; Region: Cupin_2; pfam07883
1087448007232	EDD domain protein, DegV family; Region: DegV; TIGR00762
1087448007233	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
1087448007234	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4918
1087448007235	MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms]; Region: COG3300
1087448007236	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
1087448007237	Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707
1087448007238	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1087448007239	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1087448007240	metal binding site [ion binding]; metal-binding site
1087448007241	active site
1087448007242	I-site; other site
1087448007243	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1087448007244	Putative zinc-finger; Region: zf-HC2; pfam13490
1087448007245	putative anti-sigmaE protein; Provisional; Region: PRK13920
1087448007246	Anti-sigma-K factor rskA; Region: RskA; pfam10099
1087448007247	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1087448007248	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1087448007249	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1087448007250	DNA binding residues [nucleotide binding]
1087448007251	Uncharacterized protein YrkD from Bacillus subtilis and related domains; this domain superfamily was previously known as part of DUF156; Region: BsYrkD-like_DUF156; cd10155
1087448007252	putative homodimer interface [polypeptide binding]; other site
1087448007253	putative homotetramer interface [polypeptide binding]; other site
1087448007254	putative metal binding site [ion binding]; other site
1087448007255	putative homodimer-homodimer interface [polypeptide binding]; other site
1087448007256	putative allosteric switch controlling residues; other site
1087448007257	Uncharacterized conserved protein [Function unknown]; Region: COG2353
1087448007258	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
1087448007259	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1087448007260	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
1087448007261	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1087448007262	Ca binding site [ion binding]; other site
1087448007263	active site
1087448007264	catalytic site [active]
1087448007265	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
1087448007266	transaminase; Reviewed; Region: PRK08068
1087448007267	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1087448007268	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1087448007269	homodimer interface [polypeptide binding]; other site
1087448007270	catalytic residue [active]
1087448007271	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
1087448007272	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1087448007273	Walker A/P-loop; other site
1087448007274	ATP binding site [chemical binding]; other site
1087448007275	Q-loop/lid; other site
1087448007276	ABC transporter signature motif; other site
1087448007277	Walker B; other site
1087448007278	D-loop; other site
1087448007279	H-loop/switch region; other site
1087448007280	NIL domain; Region: NIL; pfam09383
1087448007281	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1087448007282	dimer interface [polypeptide binding]; other site
1087448007283	conserved gate region; other site
1087448007284	ABC-ATPase subunit interface; other site
1087448007285	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1087448007286	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1087448007287	Uncharacterized protein with SCP/PR1 domains [Function unknown]; Region: COG2340
1087448007288	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
1087448007289	Predicted extracellular nuclease [General function prediction only]; Region: COG2374
1087448007290	Fn3 associated; Region: Fn3_assoc; pfam13287
1087448007291	YhcR_OBF_like: A subfamily of OB-fold domains similar to the OB folds of Bacillus subtilis YhcR. YhcR is a sugar-nonspecific nuclease, which is active in the presence of Ca2+ and Mn2+. It cleaves RNA endonucleolytically, producing 3'-monophosphate...; Region: YhcR_OBF_like; cd04486
1087448007292	generic binding surface II; other site
1087448007293	generic binding surface I; other site
1087448007294	Mycoplasma pulmonis MnuA nuclease-like; Region: MnuA_DNase1-like; cd10283
1087448007295	putative active site [active]
1087448007296	putative catalytic site [active]
1087448007297	putative Mg binding site IVb [ion binding]; other site
1087448007298	putative phosphate binding site [ion binding]; other site
1087448007299	putative DNA binding site [nucleotide binding]; other site
1087448007300	putative Mg binding site IVa [ion binding]; other site
1087448007301	Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]; Region: COG1331
1087448007302	TRX domain, SSP411 protein family; members of this family are highly conserved proteins present in eukaryotes, bacteria and archaea, about 600-800 amino acids in length, which contain a TRX domain with a redox active CXXC motif. The human/rat protein; Region: SSP411; cd02955
1087448007303	catalytic residues [active]
1087448007304	Bacterial SH3 domain; Region: SH3_3; cl17532
1087448007305	Bacterial SH3 domain; Region: SH3_3; pfam08239
1087448007306	Bacterial SH3 domain; Region: SH3_3; pfam08239
1087448007307	SH3 domain protein [Signal transduction mechanisms]; Region: COG3103
1087448007308	Bacterial SH3 domain; Region: SH3_3; pfam08239
1087448007309	Bacterial SH3 domain; Region: SH3_3; cl17532
1087448007310	Beta- N-acetylglucosaminidase [Carbohydrate transport and metabolism]; Region: LytD; COG4193
1087448007311	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; cl17361
1087448007312	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
1087448007313	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
1087448007314	Ligand Binding Site [chemical binding]; other site
1087448007315	K+-transporting ATPase, c chain; Region: KdpC; cl00944
1087448007316	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
1087448007317	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1087448007318	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1087448007319	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
1087448007320	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
1087448007321	catalytic residues [active]
1087448007322	dimer interface [polypeptide binding]; other site
1087448007323	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
1087448007324	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
1087448007325	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Region: Glyphos_transf; pfam04464
1087448007326	Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC [Cell envelope biogenesis, outer membrane]; Region: TagB; COG1887
1087448007327	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Region: Glyphos_transf; pfam04464
1087448007328	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1087448007329	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1087448007330	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
1087448007331	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1087448007332	AmiS/UreI family transporter; Region: AmiS_UreI; pfam02293
1087448007333	Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; cl00581
1087448007334	rod shape-determining protein MreC; Provisional; Region: PRK13922
1087448007335	aminotransferase, LLPSF_NHT_00031 family; Region: NHT_00031; TIGR04181
1087448007336	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1087448007337	inhibitor-cofactor binding pocket; inhibition site
1087448007338	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1087448007339	catalytic residue [active]
1087448007340	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
1087448007341	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1087448007342	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
1087448007343	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1087448007344	putative ADP-binding pocket [chemical binding]; other site
1087448007345	UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: WecC; COG0677
1087448007346	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1087448007347	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1087448007348	Coenzyme F390 synthetase [Coenzyme metabolism]; Region: PaaK; COG1541
1087448007349	putative adenylate-forming enzyme; Region: aden_form_hyp; TIGR02304
1087448007350	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1087448007351	UDP glucuronic acid epimerase, extended (e) SDRs; Region: UDP_GE_SDE_e; cd05253
1087448007352	putative NAD(P) binding site [chemical binding]; other site
1087448007353	active site
1087448007354	putative substrate binding site [chemical binding]; other site
1087448007355	Predicted membrane-associated HD superfamily hydrolase [General function prediction only]; Region: COG1480
1087448007356	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1087448007357	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1087448007358	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
1087448007359	CoA binding domain; Region: CoA_binding; cl17356
1087448007360	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
1087448007361	Polysaccharide biosynthesis protein; Region: Polysacc_synt_2; pfam02719
1087448007362	NAD(P) binding site [chemical binding]; other site
1087448007363	homodimer interface [polypeptide binding]; other site
1087448007364	substrate binding site [chemical binding]; other site
1087448007365	active site
1087448007366	Chain length determinant protein; Region: Wzz; cl15801
1087448007367	carbamoyl phosphate synthase-like protein; Provisional; Region: PRK12767
1087448007368	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
1087448007369	VanZ like family; Region: VanZ; pfam04892
1087448007370	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1087448007371	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1087448007372	non-specific DNA binding site [nucleotide binding]; other site
1087448007373	salt bridge; other site
1087448007374	sequence-specific DNA binding site [nucleotide binding]; other site
1087448007375	Possible lysine decarboxylase; Region: Lysine_decarbox; pfam03641
1087448007376	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1087448007377	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1087448007378	active site
1087448007379	tetramer interface; other site
1087448007380	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
1087448007381	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
1087448007382	Walker A/P-loop; other site
1087448007383	ATP binding site [chemical binding]; other site
1087448007384	Q-loop/lid; other site
1087448007385	ABC transporter signature motif; other site
1087448007386	Walker B; other site
1087448007387	D-loop; other site
1087448007388	H-loop/switch region; other site
1087448007389	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
1087448007390	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1087448007391	Bacterial Ig-like domain (group 4); Region: Big_4; pfam07532
1087448007392	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
1087448007393	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1087448007394	active site
1087448007395	metal binding site [ion binding]; metal-binding site
1087448007396	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1087448007397	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1087448007398	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1087448007399	Ankyrin repeats (many copies); Region: Ank_5; pfam13857
1087448007400	Ankyrin repeats (many copies); Region: Ank_5; pfam13857
1087448007401	Fatty acid desaturase [Lipid metabolism]; Region: DesA; COG3239
1087448007402	The Delta12 Fatty Acid Desaturase (Delta12-FADS)-like CD includes the integral-membrane enzymes, delta-12 acyl-lipid desaturases, oleate 12-hydroxylases, omega3 and omega6 fatty acid desaturases, and other related proteins, found in a wide range of...; Region: Delta12-FADS-like; cd03507
1087448007403	putative di-iron ligands [ion binding]; other site
1087448007404	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1087448007405	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1087448007406	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1087448007407	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
1087448007408	active site
1087448007409	DNA binding site [nucleotide binding]
1087448007410	Int/Topo IB signature motif; other site
1087448007411	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
1087448007412	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1087448007413	active site
1087448007414	DNA binding site [nucleotide binding]
1087448007415	Int/Topo IB signature motif; other site
1087448007416	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1087448007417	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1087448007418	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1087448007419	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1087448007420	active site
1087448007421	tetramer interface; other site
1087448007422	Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: CapC; COG4464
1087448007423	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
1087448007424	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1087448007425	Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane]; Region: COG3944
1087448007426	Chain length determinant protein; Region: Wzz; cl15801
1087448007427	Cell envelope-related transcriptional attenuator domain; Region: LytR_cpsA_psr; cl00581
1087448007428	Peptidase S8 family domain in Thermitase-like proteins; Region: Peptidases_S8_Thermitase_like; cd07484
1087448007429	active site
1087448007430	catalytic triad [active]
1087448007431	Peptidase S8 family domain in Thermitase-like proteins; Region: Peptidases_S8_Thermitase_like; cd07484
1087448007432	active site
1087448007433	catalytic triad [active]
1087448007434	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
1087448007435	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
1087448007436	active site
1087448007437	catalytic site [active]
1087448007438	Bacterial Ig-like domain (group 2); Region: Big_2; cl02708
1087448007439	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
1087448007440	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1087448007441	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1087448007442	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; Region: UDPG_MGDP_dh_C; pfam03720
1087448007443	Pirin; Region: Pirin; pfam02678
1087448007444	Pirin-related protein [General function prediction only]; Region: COG1741
1087448007445	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
1087448007446	Helix-turn-helix domain; Region: HTH_17; pfam12728
1087448007447	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1087448007448	DNA-directed RNA polymerase subunit beta; Region: EpuA; pfam11772
1087448007449	Sortase E (SrtE) is a membrane transpeptidase found in gram-positive bacteria that cleaves surface proteins at a cell sorting motif and catalyzes a transpeptidation reaction in which the surface protein substrate is covalently linked to peptidoglycan for...; Region: Sortase_E; cd05829
1087448007450	active site
1087448007451	putative catalytic site [active]
1087448007452	MarR family; Region: MarR_2; cl17246
1087448007453	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1087448007454	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1087448007455	HAMP domain; Region: HAMP; pfam00672
1087448007456	GAF domain; Region: GAF_3; pfam13492
1087448007457	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
1087448007458	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1087448007459	dimer interface [polypeptide binding]; other site
1087448007460	phosphorylation site [posttranslational modification]
1087448007461	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1087448007462	ATP binding site [chemical binding]; other site
1087448007463	Mg2+ binding site [ion binding]; other site
1087448007464	G-X-G motif; other site
1087448007465	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgG; COG4786
1087448007466	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1087448007467	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1087448007468	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgG; COG4786
1087448007469	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1087448007470	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; cl15855
1087448007471	PAS fold; Region: PAS_4; pfam08448
1087448007472	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1087448007473	putative active site [active]
1087448007474	heme pocket [chemical binding]; other site
1087448007475	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1087448007476	metal binding site [ion binding]; metal-binding site
1087448007477	active site
1087448007478	I-site; other site
1087448007479	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1087448007480	drug efflux system protein MdtG; Provisional; Region: PRK09874
1087448007481	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1087448007482	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1087448007483	putative substrate translocation pore; other site
1087448007484	rod shape-determining protein Mbl; Provisional; Region: PRK13928
1087448007485	MreB and similar proteins; Region: MreB_like; cd10225
1087448007486	nucleotide binding site [chemical binding]; other site
1087448007487	Mg binding site [ion binding]; other site
1087448007488	putative protofilament interaction site [polypeptide binding]; other site
1087448007489	RodZ interaction site [polypeptide binding]; other site
1087448007490	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1087448007491	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1087448007492	hinge; other site
1087448007493	active site
1087448007494	Protein of unknown function (DUF1146); Region: DUF1146; cl11486
1087448007495	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
1087448007496	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1087448007497	gamma subunit interface [polypeptide binding]; other site
1087448007498	epsilon subunit interface [polypeptide binding]; other site
1087448007499	LBP interface [polypeptide binding]; other site
1087448007500	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1087448007501	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1087448007502	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1087448007503	alpha subunit interaction interface [polypeptide binding]; other site
1087448007504	Walker A motif; other site
1087448007505	ATP binding site [chemical binding]; other site
1087448007506	Walker B motif; other site
1087448007507	inhibitor binding site; inhibition site
1087448007508	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1087448007509	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1087448007510	core domain interface [polypeptide binding]; other site
1087448007511	delta subunit interface [polypeptide binding]; other site
1087448007512	epsilon subunit interface [polypeptide binding]; other site
1087448007513	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1087448007514	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1087448007515	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1087448007516	beta subunit interaction interface [polypeptide binding]; other site
1087448007517	Walker A motif; other site
1087448007518	ATP binding site [chemical binding]; other site
1087448007519	Walker B motif; other site
1087448007520	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1087448007521	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1087448007522	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
1087448007523	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1087448007524	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
1087448007525	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
1087448007526	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
1087448007527	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1087448007528	ATP synthase I chain; Region: ATP_synt_I; pfam03899
1087448007529	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
1087448007530	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1087448007531	active site
1087448007532	homodimer interface [polypeptide binding]; other site
1087448007533	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1087448007534	active site
1087448007535	Fungal protein of unknown function (DUF1742); Region: DUF1742; pfam08432
1087448007536	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1087448007537	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1087448007538	Walker A/P-loop; other site
1087448007539	ATP binding site [chemical binding]; other site
1087448007540	Q-loop/lid; other site
1087448007541	ABC transporter signature motif; other site
1087448007542	Walker B; other site
1087448007543	D-loop; other site
1087448007544	H-loop/switch region; other site
1087448007545	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1087448007546	FtsX-like permease family; Region: FtsX; pfam02687
1087448007547	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1087448007548	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1087448007549	dimerization interface [polypeptide binding]; other site
1087448007550	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1087448007551	dimer interface [polypeptide binding]; other site
1087448007552	phosphorylation site [posttranslational modification]
1087448007553	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1087448007554	ATP binding site [chemical binding]; other site
1087448007555	Mg2+ binding site [ion binding]; other site
1087448007556	G-X-G motif; other site
1087448007557	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1087448007558	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1087448007559	active site
1087448007560	phosphorylation site [posttranslational modification]
1087448007561	intermolecular recognition site; other site
1087448007562	dimerization interface [polypeptide binding]; other site
1087448007563	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1087448007564	DNA binding site [nucleotide binding]
1087448007565	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
1087448007566	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1087448007567	dimer interface [polypeptide binding]; other site
1087448007568	active site
1087448007569	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1087448007570	folate binding site [chemical binding]; other site
1087448007571	hypothetical protein; Provisional; Region: PRK13690
1087448007572	ribose-5-phosphate isomerase B; Provisional; Region: PRK05571
1087448007573	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
1087448007574	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1087448007575	active site
1087448007576	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
1087448007577	Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481
1087448007578	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
1087448007579	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1087448007580	S-adenosylmethionine binding site [chemical binding]; other site
1087448007581	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1087448007582	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1087448007583	RF-1 domain; Region: RF-1; pfam00472
1087448007584	Predicted transcriptional regulators [Transcription]; Region: COG1725
1087448007585	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1087448007586	DNA-binding site [nucleotide binding]; DNA binding site
1087448007587	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1087448007588	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1087448007589	Walker A/P-loop; other site
1087448007590	ATP binding site [chemical binding]; other site
1087448007591	Q-loop/lid; other site
1087448007592	ABC transporter signature motif; other site
1087448007593	Walker B; other site
1087448007594	D-loop; other site
1087448007595	H-loop/switch region; other site
1087448007596	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1087448007597	DNA-binding site [nucleotide binding]; DNA binding site
1087448007598	trehalose operon repressor, B. subtilis-type; Region: trehalos_R_Bsub; TIGR02404
1087448007599	UTRA domain; Region: UTRA; pfam07702
1087448007600	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1087448007601	PAS domain; Region: PAS_9; pfam13426
1087448007602	putative active site [active]
1087448007603	heme pocket [chemical binding]; other site
1087448007604	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
1087448007605	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1087448007606	putative active site [active]
1087448007607	heme pocket [chemical binding]; other site
1087448007608	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1087448007609	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1087448007610	metal binding site [ion binding]; metal-binding site
1087448007611	active site
1087448007612	I-site; other site
1087448007613	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1087448007614	PTS system, trehalose-specific IIBC component; Region: PTS-IIBC-Tre; TIGR01992
1087448007615	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1087448007616	active site turn [active]
1087448007617	phosphorylation site [posttranslational modification]
1087448007618	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1087448007619	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
1087448007620	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1087448007621	Ca binding site [ion binding]; other site
1087448007622	active site
1087448007623	catalytic site [active]
1087448007624	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1087448007625	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
1087448007626	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016
1087448007627	dimer interface [polypeptide binding]; other site
1087448007628	Alkaline phosphatase homologues; Region: alkPPc; smart00098
1087448007629	active site
1087448007630	Domain of unknown function (DUF4352); Region: DUF4352; pfam11611
1087448007631	PAS domain S-box; Region: sensory_box; TIGR00229
1087448007632	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1087448007633	putative active site [active]
1087448007634	heme pocket [chemical binding]; other site
1087448007635	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1087448007636	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1087448007637	metal binding site [ion binding]; metal-binding site
1087448007638	active site
1087448007639	I-site; other site
1087448007640	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1087448007641	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
1087448007642	homopentamer interface [polypeptide binding]; other site
1087448007643	active site
1087448007644	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09311
1087448007645	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
1087448007646	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
1087448007647	dimerization interface [polypeptide binding]; other site
1087448007648	active site
1087448007649	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
1087448007650	Lumazine binding domain; Region: Lum_binding; pfam00677
1087448007651	Lumazine binding domain; Region: Lum_binding; pfam00677
1087448007652	riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326
1087448007653	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
1087448007654	catalytic motif [active]
1087448007655	Zn binding site [ion binding]; other site
1087448007656	RibD C-terminal domain; Region: RibD_C; pfam01872
1087448007657	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1087448007658	M20 Peptidase Aminoacylase 1-like protein 2-like, amidohydrolase subfamily; Region: M20_ACY1L2_like; cd05672
1087448007659	metal binding site [ion binding]; metal-binding site
1087448007660	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1087448007661	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1087448007662	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1087448007663	dimer interface [polypeptide binding]; other site
1087448007664	conserved gate region; other site
1087448007665	ABC-ATPase subunit interface; other site
1087448007666	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
1087448007667	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1087448007668	Walker A/P-loop; other site
1087448007669	ATP binding site [chemical binding]; other site
1087448007670	Q-loop/lid; other site
1087448007671	ABC transporter signature motif; other site
1087448007672	Walker B; other site
1087448007673	D-loop; other site
1087448007674	H-loop/switch region; other site
1087448007675	NIL domain; Region: NIL; pfam09383
1087448007676	Esterase/lipase [General function prediction only]; Region: COG1647
1087448007677	thymidine kinase; Provisional; Region: PRK04296
1087448007678	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1087448007679	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1087448007680	transcription termination factor Rho; Provisional; Region: rho; PRK09376
1087448007681	Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498
1087448007682	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1087448007683	RNA binding site [nucleotide binding]; other site
1087448007684	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1087448007685	multimer interface [polypeptide binding]; other site
1087448007686	Walker A motif; other site
1087448007687	ATP binding site [chemical binding]; other site
1087448007688	Walker B motif; other site
1087448007689	Bacterial SH3 domain; Region: SH3_3; pfam08239
1087448007690	NlpC/P60 family; Region: NLPC_P60; pfam00877
1087448007691	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
1087448007692	classical (c) SDRs; Region: SDR_c; cd05233
1087448007693	NAD(P) binding site [chemical binding]; other site
1087448007694	active site
1087448007695	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
1087448007696	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
1087448007697	putative active site [active]
1087448007698	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1087448007699	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1087448007700	hinge; other site
1087448007701	active site
1087448007702	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
1087448007703	active site
1087448007704	intersubunit interactions; other site
1087448007705	catalytic residue [active]
1087448007706	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1087448007707	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1087448007708	intersubunit interface [polypeptide binding]; other site
1087448007709	active site
1087448007710	zinc binding site [ion binding]; other site
1087448007711	Na+ binding site [ion binding]; other site
1087448007712	Response regulator receiver domain; Region: Response_reg; pfam00072
1087448007713	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1087448007714	active site
1087448007715	phosphorylation site [posttranslational modification]
1087448007716	intermolecular recognition site; other site
1087448007717	dimerization interface [polypeptide binding]; other site
1087448007718	Protein of unknown function (DUF2529); Region: DUF2529; pfam10740
1087448007719	CTP synthetase; Validated; Region: pyrG; PRK05380
1087448007720	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1087448007721	Catalytic site [active]
1087448007722	active site
1087448007723	UTP binding site [chemical binding]; other site
1087448007724	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1087448007725	active site
1087448007726	putative oxyanion hole; other site
1087448007727	catalytic triad [active]
1087448007728	DNA-directed RNA polymerase delta subunit; Region: RNA_pol_delta; pfam05066
1087448007729	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1087448007730	Coenzyme A binding pocket [chemical binding]; other site
1087448007731	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1087448007732	dimerization interface [polypeptide binding]; other site
1087448007733	putative DNA binding site [nucleotide binding]; other site
1087448007734	putative Zn2+ binding site [ion binding]; other site
1087448007735	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1087448007736	Protein of unknown function, DUF606; Region: DUF606; pfam04657
1087448007737	Domain of unknown function (DUF336); Region: DUF336; cl01249
1087448007738	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1087448007739	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1087448007740	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1087448007741	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
1087448007742	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1087448007743	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1087448007744	NADP binding site [chemical binding]; other site
1087448007745	active site
1087448007746	steroid binding site; other site
1087448007747	PAS domain S-box; Region: sensory_box; TIGR00229
1087448007748	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1087448007749	putative active site [active]
1087448007750	heme pocket [chemical binding]; other site
1087448007751	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1087448007752	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1087448007753	metal binding site [ion binding]; metal-binding site
1087448007754	active site
1087448007755	I-site; other site
1087448007756	Ion channel; Region: Ion_trans_2; pfam07885
1087448007757	Domain of unknown function (DUF1975); Region: DUF1975; pfam09318
1087448007758	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1087448007759	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1087448007760	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
1087448007761	MgtE intracellular N domain; Region: MgtE_N; pfam03448
1087448007762	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
1087448007763	Divalent cation transporter; Region: MgtE; pfam01769
1087448007764	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
1087448007765	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1087448007766	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1087448007767	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1087448007768	ABC-ATPase subunit  interface; other site
1087448007769	dimer interface [polypeptide binding]; other site
1087448007770	putative PBP binding regions; other site
1087448007771	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
1087448007772	Metal binding protein PsaA.  These proteins have been shown to function as initial receptors in ABC transport of Mn2+ and as surface adhesins in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that...; Region: PsaA; cd01137
1087448007773	metal binding site [ion binding]; metal-binding site
1087448007774	Protein of unknown function with PCYCGC motif; Region: PCYCGC; pfam13798
1087448007775	Arginate lyase and other MDR family members; Region: AL_MDR; cd08252
1087448007776	zinc-binding alcohol dehydrogenase family protein; Region: adh_fam_1; TIGR02817
1087448007777	putative NAD(P) binding site [chemical binding]; other site
1087448007778	dimer interface [polypeptide binding]; other site
1087448007779	HAMP domain; Region: HAMP; pfam00672
1087448007780	dimerization interface [polypeptide binding]; other site
1087448007781	GAF domain; Region: GAF; cl17456
1087448007782	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1087448007783	dimer interface [polypeptide binding]; other site
1087448007784	phosphorylation site [posttranslational modification]
1087448007785	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1087448007786	ATP binding site [chemical binding]; other site
1087448007787	Mg2+ binding site [ion binding]; other site
1087448007788	G-X-G motif; other site
1087448007789	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1087448007790	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1087448007791	Uncharacterized protein conserved in bacteria (DUF2332); Region: DUF2332; pfam10094
1087448007792	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1087448007793	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
1087448007794	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
1087448007795	Probable transposase; Region: OrfB_IS605; pfam01385
1087448007796	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
1087448007797	NADH dehydrogenase subunit 6; Provisional; Region: ND6; cl17265
1087448007798	Sulfatase; Region: Sulfatase; pfam00884
1087448007799	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1087448007800	Coenzyme A binding pocket [chemical binding]; other site
1087448007801	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1087448007802	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1087448007803	ring oligomerisation interface [polypeptide binding]; other site
1087448007804	ATP/Mg binding site [chemical binding]; other site
1087448007805	stacking interactions; other site
1087448007806	hinge regions; other site
1087448007807	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1087448007808	oligomerisation interface [polypeptide binding]; other site
1087448007809	mobile loop; other site
1087448007810	roof hairpin; other site
1087448007811	CAAX protease self-immunity; Region: Abi; pfam02517
1087448007812	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1087448007813	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
1087448007814	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
1087448007815	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1087448007816	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1087448007817	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1087448007818	Walker A/P-loop; other site
1087448007819	ATP binding site [chemical binding]; other site
1087448007820	Q-loop/lid; other site
1087448007821	ABC transporter signature motif; other site
1087448007822	Walker B; other site
1087448007823	D-loop; other site
1087448007824	H-loop/switch region; other site
1087448007825	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1087448007826	Periplasmic binding protein FeuA.  These proteins have predicted to function as initial receptors in ABC transport of metal ions in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct...; Region: FeuA; cd01138
1087448007827	putative ligand binding residues [chemical binding]; other site
1087448007828	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
1087448007829	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1087448007830	ABC-ATPase subunit  interface; other site
1087448007831	dimer interface [polypeptide binding]; other site
1087448007832	putative PBP binding regions; other site
1087448007833	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1087448007834	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1087448007835	ABC-ATPase subunit  interface; other site
1087448007836	dimer interface [polypeptide binding]; other site
1087448007837	putative PBP binding regions; other site
1087448007838	Subtilisin-like serine proteases [Posttranslational modification, protein turnover, chaperones]; Region: AprE; COG1404
1087448007839	Peptidase S8 family domain in Streptococcal C5a peptidases; Region: Peptidases_S8_C5a_Peptidase; cd07475
1087448007840	putative active site [active]
1087448007841	catalytic triad [active]
1087448007842	PA: Protease-associated (PA) domain. The PA domain is an insert domain in a diverse fraction of proteases. The significance of the PA domain to many of the proteins in which it is inserted is undetermined. It may be a protein-protein interaction domain; Region: PA; cl08238
1087448007843	PA/protease or protease-like domain interface [polypeptide binding]; other site
1087448007844	Peptidase S8 family domain in Streptococcal C5a peptidases; Region: Peptidases_S8_C5a_Peptidase; cd07475
1087448007845	Fn3-like domain (DUF1034); Region: DUF1034; pfam06280
1087448007846	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
1087448007847	twin arginine translocase protein A; Provisional; Region: tatA; PRK14861
1087448007848	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
1087448007849	Predicted membrane protein [Function unknown]; Region: COG2259
1087448007850	Predicted transcriptional regulators [Transcription]; Region: COG1733
1087448007851	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1087448007852	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1087448007853	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1087448007854	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1087448007855	2-haloalkanoic acid dehalogenase, type II; Region: HAD_type_II; TIGR01428
1087448007856	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1087448007857	motif II; other site
1087448007858	UGMP family protein; Validated; Region: PRK09604
1087448007859	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
1087448007860	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1087448007861	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
1087448007862	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1087448007863	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1087448007864	Glycoprotease family; Region: Peptidase_M22; pfam00814
1087448007865	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
1087448007866	hypothetical protein; Provisional; Region: PRK04351
1087448007867	SprT homologues; Region: SprT; cl01182
1087448007868	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
1087448007869	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
1087448007870	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
1087448007871	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
1087448007872	RNA binding site [nucleotide binding]; other site
1087448007873	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1087448007874	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1087448007875	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1087448007876	DNA binding residues [nucleotide binding]
1087448007877	Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; Region: RsbW; COG2172
1087448007878	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1087448007879	ATP binding site [chemical binding]; other site
1087448007880	Mg2+ binding site [ion binding]; other site
1087448007881	G-X-G motif; other site
1087448007882	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
1087448007883	anti sigma factor interaction site; other site
1087448007884	regulatory phosphorylation site [posttranslational modification]; other site
1087448007885	PemK-like protein; Region: PemK; pfam02452
1087448007886	Alanine racemase [Cell envelope biogenesis, outer membrane]; Region: Alr; COG0787
1087448007887	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
1087448007888	active site
1087448007889	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1087448007890	dimer interface [polypeptide binding]; other site
1087448007891	substrate binding site [chemical binding]; other site
1087448007892	catalytic residues [active]
1087448007893	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
1087448007894	Rhomboid family; Region: Rhomboid; pfam01694
1087448007895	PCD_DCoH: The bifunctional protein pterin-4alpha-carbinolamine dehydratase (PCD), also known as DCoH  (dimerization cofactor of hepatocyte nuclear factor-1), is both a transcription activator and a metabolic enzyme.  DCoH stimulates gene expression by...; Region: PCD_DCoH; cd00488
1087448007896	aromatic arch; other site
1087448007897	DCoH dimer interaction site [polypeptide binding]; other site
1087448007898	DCoH /HNF-1 dimer interaction site [polypeptide binding]; other site
1087448007899	DCoH tetramer interaction site [polypeptide binding]; other site
1087448007900	substrate binding site [chemical binding]; other site
1087448007901	Isochorismatase family; Region: Isochorismatase; pfam00857
1087448007902	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1087448007903	catalytic triad [active]
1087448007904	conserved cis-peptide bond; other site
1087448007905	nicotinate phosphoribosyltransferase; Validated; Region: PRK09243
1087448007906	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
1087448007907	active site
1087448007908	YwpF-like protein; Region: YwpF; pfam14183
1087448007909	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1087448007910	catalytic core [active]
1087448007911	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1087448007912	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1087448007913	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
1087448007914	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1087448007915	intersubunit interface [polypeptide binding]; other site
1087448007916	Na+/H+ antiporter [Energy production and conversion]; Region: NhaC; COG1757
1087448007917	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1087448007918	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1087448007919	active site
1087448007920	catalytic tetrad [active]
1087448007921	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1087448007922	amino acid carrier protein; Region: agcS; TIGR00835
1087448007923	CoA-disulfide reductase; Region: CoA_CoA_reduc; TIGR03385
1087448007924	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1087448007925	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1087448007926	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1087448007927	Member of the Rhodanese Homology Domain superfamily. Included in this CD are the Lactococcus lactis NADH oxidase, Bacillus cereus NADH dehydrogenase, and Bacteroides thetaiotaomicron pyridine nucleotide-disulphide oxidoreductase, and similar...; Region: RHOD_Pyr_redox; cd01524
1087448007928	active site residue [active]
1087448007929	SirA_RHOD_Pry_redox.    SirA-like domain located within a multidomain protein of unknown function. Other domains include RHOD (rhodanese homology domain), and Pry_redox (pyridine nucleotide-disulphide oxidoreductase) as well as a C-terminal domain that...; Region: SirA_RHOD_Pry_redox; cd03420
1087448007930	CPxP  motif; other site
1087448007931	DsrE/DsrF/DrsH-like family; Region: DrsE_2; pfam13686
1087448007932	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
1087448007933	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1087448007934	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1087448007935	NAD(P) binding site [chemical binding]; other site
1087448007936	active site
1087448007937	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
1087448007938	Sulfatase; Region: Sulfatase; cl17466
1087448007939	Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663
1087448007940	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
1087448007941	DXD motif; other site
1087448007942	Putative Catalytic site; other site
1087448007943	Iron permease FTR1 family; Region: FTR1; cl00475
1087448007944	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1087448007945	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1087448007946	Coenzyme A binding pocket [chemical binding]; other site
1087448007947	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1087448007948	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1087448007949	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1087448007950	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
1087448007951	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1087448007952	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1087448007953	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1087448007954	oxidoreductase; Provisional; Region: PRK07985
1087448007955	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
1087448007956	NAD binding site [chemical binding]; other site
1087448007957	metal binding site [ion binding]; metal-binding site
1087448007958	active site
1087448007959	maltose O-acetyltransferase; Provisional; Region: PRK10092
1087448007960	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
1087448007961	active site
1087448007962	substrate binding site [chemical binding]; other site
1087448007963	trimer interface [polypeptide binding]; other site
1087448007964	CoA binding site [chemical binding]; other site
1087448007965	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1087448007966	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1087448007967	active site
1087448007968	phosphorylation site [posttranslational modification]
1087448007969	intermolecular recognition site; other site
1087448007970	dimerization interface [polypeptide binding]; other site
1087448007971	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1087448007972	DNA binding site [nucleotide binding]
1087448007973	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1087448007974	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1087448007975	dimerization interface [polypeptide binding]; other site
1087448007976	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1087448007977	dimer interface [polypeptide binding]; other site
1087448007978	phosphorylation site [posttranslational modification]
1087448007979	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1087448007980	ATP binding site [chemical binding]; other site
1087448007981	Mg2+ binding site [ion binding]; other site
1087448007982	G-X-G motif; other site
1087448007983	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
1087448007984	active site
1087448007985	putative substrate binding region [chemical binding]; other site
1087448007986	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1087448007987	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
1087448007988	an uncharacterized bacterial subgroup of the DEDDh 3'-5' exonuclease domain family with similarity to the epsilon subunit of DNA polymerase III; Region: DNA_pol_III_epsilon_like; cd06130
1087448007989	active site
1087448007990	catalytic site [active]
1087448007991	substrate binding site [chemical binding]; other site
1087448007992	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1087448007993	Old yellow enzyme (OYE)-related FMN binding domain, group 4.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as...; Region: OYE_like_4_FMN; cd04735
1087448007994	putative active site [active]
1087448007995	putative FMN binding site [chemical binding]; other site
1087448007996	putative substrate binding site [chemical binding]; other site
1087448007997	putative catalytic residue [active]
1087448007998	Predicted exporters of the RND superfamily [General function prediction only]; Region: COG1033
1087448007999	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
1087448008000	YycC-like protein; Region: YycC; pfam14174
1087448008001	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
1087448008002	active site
1087448008003	pullulanase, type I; Region: pulA_typeI; TIGR02104
1087448008004	Early set domain associated with the catalytic domain of pullulanase (also called dextrinase and alpha-dextrin endo-1,6-alpha glucosidase); Region: E_set_Pullulanase; cd02860
1087448008005	Alpha amylase catalytic domain found in Pullulanase (also called dextrinase; alpha-dextrin endo-1,6-alpha glucosidase), limit dextrinase, and related proteins; Region: AmyAc_Pullulanase_LD-like; cd11341
1087448008006	Ca binding site [ion binding]; other site
1087448008007	active site
1087448008008	catalytic site [active]
1087448008009	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
1087448008010	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
1087448008011	3-hydroxybutyrate dehydrogenase; Provisional; Region: PRK12429
1087448008012	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1087448008013	NAD(P) binding site [chemical binding]; other site
1087448008014	active site
1087448008015	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1087448008016	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1087448008017	The C-terminal substrate binding domain of LysR-like transcriptional regulator CidR, contains the type 2 periplasmic binding fold; Region: PBP2_CidR; cd08438
1087448008018	putative dimerization interface [polypeptide binding]; other site
1087448008019	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
1087448008020	Calcineurin-like phosphoesterase superfamily domain; Region: Metallophos_2; pfam12850
1087448008021	arginyl-tRNA synthetase; Reviewed; Region: PRK12451
1087448008022	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
1087448008023	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1087448008024	active site
1087448008025	HIGH motif; other site
1087448008026	KMSK motif region; other site
1087448008027	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
1087448008028	tRNA binding surface [nucleotide binding]; other site
1087448008029	anticodon binding site; other site
1087448008030	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1087448008031	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1087448008032	metal binding site [ion binding]; metal-binding site
1087448008033	active site
1087448008034	I-site; other site
1087448008035	Putative esterase; Region: Esterase; pfam00756
1087448008036	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1087448008037	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
1087448008038	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
1087448008039	active site residue [active]
1087448008040	Protein of unknown function (DUF3650); Region: DUF3650; pfam12368
1087448008041	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1087448008042	Protein of unknown function, DUF485; Region: DUF485; pfam04341
1087448008043	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
1087448008044	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
1087448008045	Na binding site [ion binding]; other site
1087448008046	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1087448008047	Regulator of polyketide synthase expression [Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2508
1087448008048	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1087448008049	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
1087448008050	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
1087448008051	hexamer interface [polypeptide binding]; other site
1087448008052	ligand binding site [chemical binding]; other site
1087448008053	putative active site [active]
1087448008054	NAD(P) binding site [chemical binding]; other site
1087448008055	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1087448008056	binding surface
1087448008057	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1087448008058	TPR motif; other site
1087448008059	Dolichol kinase [Lipid metabolism]; Region: SEC59; COG0170
1087448008060	Domain of unknown function (DUF1836); Region: DUF1836; pfam08876
1087448008061	Restriction endonuclease; Region: Mrr_cat; pfam04471
1087448008062	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1087448008063	PAS domain; Region: PAS_9; pfam13426
1087448008064	putative active site [active]
1087448008065	heme pocket [chemical binding]; other site
1087448008066	PAS domain S-box; Region: sensory_box; TIGR00229
1087448008067	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1087448008068	putative active site [active]
1087448008069	heme pocket [chemical binding]; other site
1087448008070	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
1087448008071	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1087448008072	dimer interface [polypeptide binding]; other site
1087448008073	phosphorylation site [posttranslational modification]
1087448008074	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1087448008075	ATP binding site [chemical binding]; other site
1087448008076	Mg2+ binding site [ion binding]; other site
1087448008077	G-X-G motif; other site
1087448008078	thioester reductase domain; Region: Thioester-redct; TIGR01746
1087448008079	Pseudomonas fluorescens MupV-like, extended (e) SDRs; Region: MupV_like_SDR_e; cd05263
1087448008080	putative NAD(P) binding site [chemical binding]; other site
1087448008081	active site
1087448008082	putative substrate binding site [chemical binding]; other site
1087448008083	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1087448008084	NAD(P) binding site [chemical binding]; other site
1087448008085	active site
1087448008086	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
1087448008087	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
1087448008088	flagellar motor protein MotA; Validated; Region: PRK08124
1087448008089	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
1087448008090	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
1087448008091	flagellar motor protein MotB; Reviewed; Region: motB; PRK07734
1087448008092	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1087448008093	ligand binding site [chemical binding]; other site
1087448008094	Protein of unknown function (DUF420); Region: DUF420; pfam04238
1087448008095	mercuric reductase; Validated; Region: PRK06370
1087448008096	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1087448008097	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1087448008098	Protein of unknown function (DUF1499); Region: DUF1499; cl01841
1087448008099	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1087448008100	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1087448008101	dimerization interface [polypeptide binding]; other site
1087448008102	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1087448008103	dimer interface [polypeptide binding]; other site
1087448008104	phosphorylation site [posttranslational modification]
1087448008105	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1087448008106	ATP binding site [chemical binding]; other site
1087448008107	Mg2+ binding site [ion binding]; other site
1087448008108	G-X-G motif; other site
1087448008109	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1087448008110	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1087448008111	active site
1087448008112	phosphorylation site [posttranslational modification]
1087448008113	intermolecular recognition site; other site
1087448008114	dimerization interface [polypeptide binding]; other site
1087448008115	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1087448008116	DNA binding site [nucleotide binding]
1087448008117	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1087448008118	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1087448008119	motif II; other site
1087448008120	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1087448008121	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1087448008122	ligand binding site [chemical binding]; other site
1087448008123	active site
1087448008124	UGI interface [polypeptide binding]; other site
1087448008125	catalytic site [active]
1087448008126	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
1087448008127	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1087448008128	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1087448008129	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1087448008130	MarR family; Region: MarR; pfam01047
1087448008131	MarR family; Region: MarR_2; cl17246
1087448008132	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1087448008133	metal ion transporter CorA-like divalent cation transporter superfamily; Region: MIT_CorA-like; cl00459
1087448008134	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1087448008135	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1087448008136	Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; Region: ProC; COG0345
1087448008137	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
1087448008138	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
1087448008139	FOG: CBS domain [General function prediction only]; Region: COG0517
1087448008140	Phosphate transport regulator (distant homolog of PhoU) [Inorganic ion transport and metabolism]; Region: COG1392
1087448008141	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1087448008142	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1087448008143	dimer interface [polypeptide binding]; other site
1087448008144	substrate binding site [chemical binding]; other site
1087448008145	ATP binding site [chemical binding]; other site
1087448008146	Protein of unknown function (DUF1806); Region: DUF1806; pfam08830
1087448008147	GlcNAc-PI de-N-acetylase; Region: PIG-L; cl00929
1087448008148	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
1087448008149	Ligand Binding Site [chemical binding]; other site
1087448008150	6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242
1087448008151	active site
1087448008152	7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: Bsubt_queE; TIGR03365
1087448008153	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
1087448008154	7-cyano-7-deazaguanine reductase; Provisional; Region: PRK13258
1087448008155	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1087448008156	non-specific DNA binding site [nucleotide binding]; other site
1087448008157	salt bridge; other site
1087448008158	sequence-specific DNA binding site [nucleotide binding]; other site
1087448008159	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1087448008160	PTS system, IIBC component; Region: PTS-II-BC-unk1; TIGR02003
1087448008161	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1087448008162	active site turn [active]
1087448008163	phosphorylation site [posttranslational modification]
1087448008164	Streptococcus agalactiae RgfB, part of a putative two component signal transduction system, and related proteins; Region: RgfB-like; cd09079
1087448008165	putative catalytic site [active]
1087448008166	putative metal binding site [ion binding]; other site
1087448008167	putative phosphate binding site [ion binding]; other site
1087448008168	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
1087448008169	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1087448008170	active site turn [active]
1087448008171	phosphorylation site [posttranslational modification]
1087448008172	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1087448008173	CAT RNA binding domain; Region: CAT_RBD; smart01061
1087448008174	transcriptional antiterminator BglG; Provisional; Region: PRK09772
1087448008175	PRD domain; Region: PRD; pfam00874
1087448008176	PRD domain; Region: PRD; pfam00874
1087448008177	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1087448008178	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
1087448008179	putative substrate binding site [chemical binding]; other site
1087448008180	putative ATP binding site [chemical binding]; other site
1087448008181	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1087448008182	Permease family; Region: Xan_ur_permease; pfam00860
1087448008183	CC3(TIP30)-like, atypical (a) SDRs; Region: CC3_like_SDR_a; cd05250
1087448008184	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
1087448008185	NAD binding site [chemical binding]; other site
1087448008186	active site
1087448008187	Glutathionylspermidine synthase preATP-grasp; Region: GSP_synth; cl00503
1087448008188	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1087448008189	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1087448008190	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1087448008191	ABC transporter; Region: ABC_tran_2; pfam12848
1087448008192	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1087448008193	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1087448008194	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1087448008195	ApbE family; Region: ApbE; pfam02424
1087448008196	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1087448008197	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1087448008198	active site
1087448008199	phosphorylation site [posttranslational modification]
1087448008200	intermolecular recognition site; other site
1087448008201	dimerization interface [polypeptide binding]; other site
1087448008202	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1087448008203	DNA binding site [nucleotide binding]
1087448008204	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1087448008205	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1087448008206	dimer interface [polypeptide binding]; other site
1087448008207	phosphorylation site [posttranslational modification]
1087448008208	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1087448008209	ATP binding site [chemical binding]; other site
1087448008210	Mg2+ binding site [ion binding]; other site
1087448008211	G-X-G motif; other site
1087448008212	Predicted membrane protein (DUF2231); Region: DUF2231; cl01730
1087448008213	helicase 45; Provisional; Region: PTZ00424
1087448008214	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1087448008215	ATP binding site [chemical binding]; other site
1087448008216	Mg++ binding site [ion binding]; other site
1087448008217	motif III; other site
1087448008218	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1087448008219	nucleotide binding region [chemical binding]; other site
1087448008220	ATP-binding site [chemical binding]; other site
1087448008221	integral membrane protein; Region: integ_memb_HG; TIGR03954
1087448008222	N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_N_like; cd08346
1087448008223	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1087448008224	Zn binding site [ion binding]; other site
1087448008225	C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_C_like; cd08347
1087448008226	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1087448008227	Zn binding site [ion binding]; other site
1087448008228	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1087448008229	DNA-binding site [nucleotide binding]; DNA binding site
1087448008230	RNA-binding motif; other site
1087448008231	Immune inhibitor A peptidase M6; Region: Peptidase_M6; cl11525
1087448008232	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1087448008233	HAMP domain; Region: HAMP; pfam00672
1087448008234	dimerization interface [polypeptide binding]; other site
1087448008235	c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206
1087448008236	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1087448008237	Zn2+ binding site [ion binding]; other site
1087448008238	Mg2+ binding site [ion binding]; other site
1087448008239	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
1087448008240	Zinc metalloprotease (elastase) [Amino acid transport and metabolism]; Region: LasB; COG3227
1087448008241	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
1087448008242	Peptidase M4 family includes thermolysin, protealysin, aureolysin and neutral protease; Region: M4_neutral_protease; cd09597
1087448008243	active site
1087448008244	Zn binding site [ion binding]; other site
1087448008245	Yhdh and yhfp-like putative quinone oxidoreductases; Region: MDR_yhdh_yhfp; cd05280
1087448008246	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
1087448008247	NADP binding site [chemical binding]; other site
1087448008248	dimer interface [polypeptide binding]; other site
1087448008249	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
1087448008250	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
1087448008251	Uncharacterized conserved protein [Function unknown]; Region: COG3342
1087448008252	Family of unknown function (DUF1028); Region: DUF1028; pfam06267
1087448008253	Putative peptidoglycan binding domain; Region: PG_binding_2; pfam08823
1087448008254	Predicted membrane protein [Function unknown]; Region: COG1288
1087448008255	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
1087448008256	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1087448008257	Uncharacterized protein containing double-stranded beta helix domain [Function unknown]; Region: COG4297
1087448008258	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1087448008259	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1087448008260	active site
1087448008261	catalytic tetrad [active]
1087448008262	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1087448008263	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1087448008264	active site
1087448008265	catalytic tetrad [active]
1087448008266	OsmC-like protein; Region: OsmC; cl00767
1087448008267	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
1087448008268	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
1087448008269	putative RNA binding site [nucleotide binding]; other site
1087448008270	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1087448008271	Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR6; cd08272
1087448008272	putative NAD(P) binding site [chemical binding]; other site
1087448008273	peptidase T; Region: peptidase-T; TIGR01882
1087448008274	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1087448008275	metal binding site [ion binding]; metal-binding site
1087448008276	dimer interface [polypeptide binding]; other site
1087448008277	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1087448008278	SPFH domain / Band 7 family; Region: Band_7; pfam01145
1087448008279	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
1087448008280	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1087448008281	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1087448008282	ABC transporter; Region: ABC_tran_2; pfam12848
1087448008283	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1087448008284	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
1087448008285	Lysine biosynthesis enzyme LysX; Region: LysX_arch; TIGR02144
1087448008286	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1087448008287	dimethyl sulfone monooxygenase SfnG; Region: LLM_DMSO2_sfnG; TIGR04021
1087448008288	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
1087448008289	active site
1087448008290	dimer interface [polypeptide binding]; other site
1087448008291	non-prolyl cis peptide bond; other site
1087448008292	insertion regions; other site
1087448008293	Protein of unknown function (DUF975); Region: DUF975; cl10504
1087448008294	Uncharacterized protein conserved in bacteria (DUF2325); Region: DUF2325; pfam10087
1087448008295	Protein of unknown function (DUF817); Region: DUF817; pfam05675
1087448008296	Predicted membrane protein [Function unknown]; Region: COG2364
1087448008297	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1087448008298	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1087448008299	putative DNA binding site [nucleotide binding]; other site
1087448008300	putative Zn2+ binding site [ion binding]; other site
1087448008301	MarR family; Region: MarR_2; cl17246
1087448008302	Nitroreductase-like family 1. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_1; cd02137
1087448008303	dimer interface [polypeptide binding]; other site
1087448008304	FMN binding site [chemical binding]; other site
1087448008305	Nitroreductase-like family 1. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_1; cd02137
1087448008306	dimer interface [polypeptide binding]; other site
1087448008307	FMN binding site [chemical binding]; other site
1087448008308	Uncharacterized FAD-dependent dehydrogenases [General function prediction only]; Region: COG2509
1087448008309	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834
1087448008310	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
1087448008311	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1087448008312	ATP binding site [chemical binding]; other site
1087448008313	Mg++ binding site [ion binding]; other site
1087448008314	motif III; other site
1087448008315	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1087448008316	nucleotide binding region [chemical binding]; other site
1087448008317	ATP-binding site [chemical binding]; other site
1087448008318	RNA recognition motif in Bacillus subtilis ATP-dependent RNA helicase YxiN and similar proteins; Region: RRM_BsYxiN_like; cd12500
1087448008319	RNA binding site [nucleotide binding]; other site
1087448008320	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14455
1087448008321	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1087448008322	FeS/SAM binding site; other site
1087448008323	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1087448008324	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1087448008325	Walker A/P-loop; other site
1087448008326	ATP binding site [chemical binding]; other site
1087448008327	Q-loop/lid; other site
1087448008328	ABC transporter signature motif; other site
1087448008329	Walker B; other site
1087448008330	D-loop; other site
1087448008331	H-loop/switch region; other site
1087448008332	Methyltransferase domain; Region: Methyltransf_32; pfam13679
1087448008333	heme-degrading monooxygenase IsdG; Provisional; Region: PRK13315
1087448008334	Uracil DNA glycosylase superfamily; Region: UDG; pfam03167
1087448008335	Na+/H+ antiporter family; Region: Na_H_antiporter; pfam03553
1087448008336	heat shock protein 90; Provisional; Region: PRK05218
1087448008337	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1087448008338	ATP binding site [chemical binding]; other site
1087448008339	Mg2+ binding site [ion binding]; other site
1087448008340	G-X-G motif; other site
1087448008341	short chain dehydrogenase; Validated; Region: PRK08589
1087448008342	classical (c) SDRs; Region: SDR_c; cd05233
1087448008343	NAD(P) binding site [chemical binding]; other site
1087448008344	active site
1087448008345	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK08588
1087448008346	Peptidase M20 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase (ArgE/DapE)-like; Region: M20_ArgE_DapE_like; cd08659
1087448008347	metal binding site [ion binding]; metal-binding site
1087448008348	dimer interface [polypeptide binding]; other site
1087448008349	Domain of unknown function (DU1801); Region: DUF1801; pfam08818
1087448008350	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1087448008351	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1087448008352	putative substrate translocation pore; other site
1087448008353	FOG: CBS domain [General function prediction only]; Region: COG0517
1087448008354	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_23; cd04636
1087448008355	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1087448008356	MarR family; Region: MarR; pfam01047
1087448008357	homocysteine methyltransferase; Provisional; Region: mmuM; PRK09485
1087448008358	Homocysteine S-methyltransferase; Region: S-methyl_trans; pfam02574
1087448008359	S-methylmethionine transporter; Provisional; Region: PRK11387
1087448008360	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
1087448008361	2-dehydropantoate 2-reductase; Provisional; Region: PRK12921
1087448008362	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
1087448008363	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
1087448008364	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1087448008365	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1087448008366	DNA-binding site [nucleotide binding]; DNA binding site
1087448008367	FCD domain; Region: FCD; pfam07729
1087448008368	gluconate kinase, FGGY type; Region: gntK_FGGY; TIGR01314
1087448008369	Gluconate kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_GntK; cd07770
1087448008370	N- and C-terminal domain interface [polypeptide binding]; other site
1087448008371	active site
1087448008372	catalytic site [active]
1087448008373	metal binding site [ion binding]; metal-binding site
1087448008374	carbohydrate binding site [chemical binding]; other site
1087448008375	ATP binding site [chemical binding]; other site
1087448008376	fructuronate transporter; Provisional; Region: PRK10034; cl15264
1087448008377	gluconate transporter; Region: gntP; TIGR00791
1087448008378	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1087448008379	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
1087448008380	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
1087448008381	peroxiredoxin; Region: AhpC; TIGR03137
1087448008382	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1087448008383	dimer interface [polypeptide binding]; other site
1087448008384	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1087448008385	catalytic triad [active]
1087448008386	peroxidatic and resolving cysteines [active]
1087448008387	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
1087448008388	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
1087448008389	catalytic residue [active]
1087448008390	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
1087448008391	catalytic residues [active]
1087448008392	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1087448008393	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1087448008394	ECF-type riboflavin transporter, S component; Region: ECF-ribofla_trS; pfam07155
1087448008395	malate:quinone oxidoreductase; Validated; Region: PRK05257
1087448008396	malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320
1087448008397	Uncharacterized protein related to deoxyribodipyrimidine photolyase [General function prediction only]; Region: COG3046
1087448008398	Deoxyribodipyrimidine photo-lyase-related protein; Region: DPRP; pfam04244
1087448008399	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
1087448008400	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1087448008401	catalytic core [active]
1087448008402	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1087448008403	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_34; cd04693
1087448008404	nudix motif; other site
1087448008405	Tubby C 2; Region: Tub_2; cl02043
1087448008406	Tubby C 2; Region: Tub_2; cl02043
1087448008407	tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis]; Region: COG0042
1087448008408	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1087448008409	FMN binding site [chemical binding]; other site
1087448008410	active site
1087448008411	catalytic residues [active]
1087448008412	substrate binding site [chemical binding]; other site
1087448008413	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
1087448008414	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1087448008415	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1087448008416	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1087448008417	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1087448008418	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
1087448008419	substrate binding pocket [chemical binding]; other site
1087448008420	Domain of unknown function (DUF4317); Region: DUF4317; pfam14199
1087448008421	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
1087448008422	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
1087448008423	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
1087448008424	Probable transposase; Region: OrfB_IS605; pfam01385
1087448008425	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
1087448008426	CxxH/CxxC protein, BA_5709 family; Region: CxxH_BA5709; TIGR04129
1087448008427	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
1087448008428	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1087448008429	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1087448008430	protein binding site [polypeptide binding]; other site
1087448008431	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
1087448008432	YycH protein; Region: YycI; pfam09648
1087448008433	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4863
1087448008434	YycH protein; Region: YycH; pfam07435
1087448008435	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: VicK; COG5002
1087448008436	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1087448008437	dimerization interface [polypeptide binding]; other site
1087448008438	PAS domain; Region: PAS; smart00091
1087448008439	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1087448008440	dimer interface [polypeptide binding]; other site
1087448008441	phosphorylation site [posttranslational modification]
1087448008442	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1087448008443	ATP binding site [chemical binding]; other site
1087448008444	Mg2+ binding site [ion binding]; other site
1087448008445	G-X-G motif; other site
1087448008446	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1087448008447	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1087448008448	active site
1087448008449	phosphorylation site [posttranslational modification]
1087448008450	intermolecular recognition site; other site
1087448008451	dimerization interface [polypeptide binding]; other site
1087448008452	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1087448008453	DNA binding site [nucleotide binding]
1087448008454	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
1087448008455	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1087448008456	GDP-binding site [chemical binding]; other site
1087448008457	ACT binding site; other site
1087448008458	IMP binding site; other site
1087448008459	replicative DNA helicase; Provisional; Region: PRK05748
1087448008460	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1087448008461	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1087448008462	Walker A motif; other site
1087448008463	ATP binding site [chemical binding]; other site
1087448008464	Walker B motif; other site
1087448008465	DNA binding loops [nucleotide binding]
1087448008466	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1087448008467	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1087448008468	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1087448008469	Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain [Signal transduction mechanisms]; Region: COG3887
1087448008470	Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967
1087448008471	DHH family; Region: DHH; pfam01368
1087448008472	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1087448008473	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1087448008474	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1087448008475	dimer interface [polypeptide binding]; other site
1087448008476	ssDNA binding site [nucleotide binding]; other site
1087448008477	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1087448008478	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1087448008479	GTP-binding protein YchF; Reviewed; Region: PRK09601
1087448008480	YchF GTPase; Region: YchF; cd01900
1087448008481	G1 box; other site
1087448008482	GTP/Mg2+ binding site [chemical binding]; other site
1087448008483	Switch I region; other site
1087448008484	G2 box; other site
1087448008485	Switch II region; other site
1087448008486	G3 box; other site
1087448008487	G4 box; other site
1087448008488	G5 box; other site
1087448008489	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1087448008490	Bacterial protein of unknown function (DUF951); Region: DUF951; pfam06107
1087448008491	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1087448008492	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1087448008493	Protein of unknown function (DUF1256); Region: DUF1256; cl06087
1087448008494	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
1087448008495	ParB-like nuclease domain; Region: ParB; smart00470
1087448008496	KorB domain; Region: KorB; pfam08535
1087448008497	nucleoid occlusion protein; Region: nucleoid_noc; TIGR04285
1087448008498	ParB-like nuclease domain; Region: ParB; smart00470
1087448008499	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
1087448008500	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1087448008501	S-adenosylmethionine binding site [chemical binding]; other site
1087448008502	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1087448008503	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
1087448008504	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
1087448008505	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1087448008506	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
1087448008507	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1087448008508	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1087448008509	G1 box; other site
1087448008510	GTP/Mg2+ binding site [chemical binding]; other site
1087448008511	Switch I region; other site
1087448008512	G2 box; other site
1087448008513	Switch II region; other site
1087448008514	G3 box; other site
1087448008515	G4 box; other site
1087448008516	G5 box; other site
1087448008517	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1087448008518	60Kd inner membrane protein; Region: 60KD_IMP; cl00489
1087448008519	Preprotein translocase subunit YidC [Intracellular trafficking and secretion]; Region: YidC; COG0706
1087448008520	ribonuclease P; Reviewed; Region: rnpA; PRK00499