-- dump date   	20140619_093813
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1034807000001	ribonuclease R; Region: RNase_R; TIGR02063
1034807000002	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1034807000003	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1034807000004	RNB domain; Region: RNB; pfam00773
1034807000005	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
1034807000006	RNA binding site [nucleotide binding]; other site
1034807000007	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
1034807000008	LysE type translocator; Region: LysE; cl00565
1034807000009	Dihydroneopterin aldolase; Region: FolB; pfam02152
1034807000010	active site
1034807000011	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
1034807000012	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1034807000013	active site
1034807000014	HIGH motif; other site
1034807000015	nucleotide binding site [chemical binding]; other site
1034807000016	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
1034807000017	KMSKS motif; other site
1034807000018	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
1034807000019	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1034807000020	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1034807000021	HIGH motif; other site
1034807000022	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1034807000023	active site
1034807000024	KMSKS motif; other site
1034807000025	Uncharacterized protein conserved in bacteria with the myosin-like domain [Function unknown]; Region: COG4372
1034807000026	Uncharacterized protein family UPF0054; Region: UPF0054; pfam02130
1034807000027	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1034807000028	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
1034807000029	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1034807000030	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1034807000031	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034807000032	S-adenosylmethionine binding site [chemical binding]; other site
1034807000033	Outer membrane protein (OmpH-like); Region: OmpH; smart00935
1034807000034	AAA domain; Region: AAA_30; pfam13604
1034807000035	Family description; Region: UvrD_C_2; pfam13538
1034807000036	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1034807000037	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1034807000038	putative acyl-acceptor binding pocket; other site
1034807000039	glucose-1-phosphate thymidylylransferase, long form; Region: rmlA_long; TIGR01208
1034807000040	NTP_transferases catalyze the transfer of nucleotides onto phosphosugars; Region: NTP_transferase; cd04181
1034807000041	active site
1034807000042	Substrate binding site; other site
1034807000043	Mg++ binding site; other site
1034807000044	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1034807000045	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034807000046	binding surface
1034807000047	TPR motif; other site
1034807000048	TPR repeat; Region: TPR_11; pfam13414
1034807000049	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034807000050	binding surface
1034807000051	TPR motif; other site
1034807000052	Domain of unknown function (DUF4292); Region: DUF4292; pfam14125
1034807000053	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1034807000054	Peptidase family M23; Region: Peptidase_M23; pfam01551
1034807000055	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034807000056	non-specific DNA binding site [nucleotide binding]; other site
1034807000057	salt bridge; other site
1034807000058	sequence-specific DNA binding site [nucleotide binding]; other site
1034807000059	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
1034807000060	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
1034807000061	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
1034807000062	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
1034807000063	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807000064	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
1034807000065	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034807000066	S-adenosylmethionine binding site [chemical binding]; other site
1034807000067	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
1034807000068	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
1034807000069	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
1034807000070	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1034807000071	GIY-YIG motif/motif A; other site
1034807000072	active site
1034807000073	catalytic site [active]
1034807000074	putative DNA binding site [nucleotide binding]; other site
1034807000075	metal binding site [ion binding]; metal-binding site
1034807000076	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1034807000077	short chain dehydrogenase; Provisional; Region: PRK06180
1034807000078	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1034807000079	NADP binding site [chemical binding]; other site
1034807000080	active site
1034807000081	steroid binding site; other site
1034807000082	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1034807000083	Helix-turn-helix domain; Region: HTH_18; pfam12833
1034807000084	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1034807000085	DNA protecting protein DprA; Region: dprA; TIGR00732
1034807000086	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
1034807000087	Sporulation related domain; Region: SPOR; pfam05036
1034807000088	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
1034807000089	Predicted metalloendopeptidase [Posttranslational modification, protein turnover, chaperones]; Region: PepO; COG3590
1034807000090	Peptidase family M13 includes neprilysin, endothelin-converting enzyme I; Region: M13; cd08662
1034807000091	active site
1034807000092	Zn binding site [ion binding]; other site
1034807000093	thymidine kinase; Provisional; Region: PRK04296
1034807000094	putative bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase/alanine racemase; Provisional; Region: PRK11930
1034807000095	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1034807000096	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1034807000097	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
1034807000098	active site
1034807000099	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1034807000100	dimer interface [polypeptide binding]; other site
1034807000101	substrate binding site [chemical binding]; other site
1034807000102	catalytic residues [active]
1034807000103	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
1034807000104	putative active site [active]
1034807000105	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
1034807000106	putative active site [active]
1034807000107	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
1034807000108	putative active site [active]
1034807000109	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034807000110	AAA domain; Region: AAA_17; pfam13207
1034807000111	AAA domain; Region: AAA_21; pfam13304
1034807000112	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
1034807000113	active site
1034807000114	putative DNA-binding cleft [nucleotide binding]; other site
1034807000115	dimer interface [polypeptide binding]; other site
1034807000116	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
1034807000117	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
1034807000118	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034807000119	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1034807000120	putative substrate translocation pore; other site
1034807000121	putative peptidase; Provisional; Region: PRK11649
1034807000122	Peptidase family M23; Region: Peptidase_M23; pfam01551
1034807000123	Tryptophan 2,3-dioxygenase; Region: Trp_dioxygenase; cl03994
1034807000124	Protein of unknown function (DUF3108); Region: DUF3108; pfam11306
1034807000125	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
1034807000126	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1034807000127	putative metal binding site [ion binding]; other site
1034807000128	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
1034807000129	REG-2-like, HAD superfamily (subfamily IA) hydrolase; Region: DREG-2; TIGR02252
1034807000130	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
1034807000131	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1034807000132	putative metal binding site [ion binding]; other site
1034807000133	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
1034807000134	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1034807000135	putative metal binding site [ion binding]; other site
1034807000136	Toxic anion resistance protein (TelA); Region: TelA; pfam05816
1034807000137	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
1034807000138	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1034807000139	putative metal binding site [ion binding]; other site
1034807000140	Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 [Signal transduction mechanisms]; Region: TerZ; COG2310
1034807000141	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
1034807000142	putative metal binding site [ion binding]; other site
1034807000143	VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subfamily; cd01464
1034807000144	metal ion-dependent adhesion site (MIDAS); other site
1034807000145	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
1034807000146	metal ion-dependent adhesion site (MIDAS); other site
1034807000147	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
1034807000148	metal ion-dependent adhesion site (MIDAS); other site
1034807000149	Protein phosphatase 2C; Region: PP2C_2; pfam13672
1034807000150	Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair]; Region: SPS1; COG0515
1034807000151	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
1034807000152	substrate binding site [chemical binding]; other site
1034807000153	activation loop (A-loop); other site
1034807000154	Integral membrane protein TerC family; Region: TerC; cl10468
1034807000155	ferrochelatase; Reviewed; Region: hemH; PRK00035
1034807000156	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1034807000157	C-terminal domain interface [polypeptide binding]; other site
1034807000158	active site
1034807000159	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1034807000160	active site
1034807000161	N-terminal domain interface [polypeptide binding]; other site
1034807000162	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
1034807000163	DNA methylase; Region: N6_N4_Mtase; pfam01555
1034807000164	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
1034807000165	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1034807000166	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1034807000167	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
1034807000168	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
1034807000169	tRNA; other site
1034807000170	putative tRNA binding site [nucleotide binding]; other site
1034807000171	putative NADP binding site [chemical binding]; other site
1034807000172	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
1034807000173	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
1034807000174	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cl17708
1034807000175	domain interfaces; other site
1034807000176	active site
1034807000177	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
1034807000178	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
1034807000179	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
1034807000180	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1034807000181	active site
1034807000182	Uroporphyrinogen-III synthase [Coenzyme metabolism]; Region: HemD; COG1587
1034807000183	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
1034807000184	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
1034807000185	substrate binding site [chemical binding]; other site
1034807000186	active site
1034807000187	Transposase IS200 like; Region: Y1_Tnp; cl00848
1034807000188	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
1034807000189	Coproporphyrinogen III oxidase; Region: Coprogen_oxidas; pfam01218
1034807000190	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
1034807000191	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
1034807000192	active site residue [active]
1034807000193	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1034807000194	DNA photolyase; Region: DNA_photolyase; pfam00875
1034807000195	Peptidase family U32; Region: Peptidase_U32; pfam01136
1034807000196	4Fe-4S single cluster domain; Region: Fer4_13; pfam13370
1034807000197	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
1034807000198	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1034807000199	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034807000200	ATP binding site [chemical binding]; other site
1034807000201	Mg2+ binding site [ion binding]; other site
1034807000202	G-X-G motif; other site
1034807000203	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
1034807000204	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1034807000205	Zn2+ binding site [ion binding]; other site
1034807000206	Mg2+ binding site [ion binding]; other site
1034807000207	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1034807000208	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1034807000209	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1034807000210	DNA polymerase I; Provisional; Region: PRK05755
1034807000211	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1034807000212	active site
1034807000213	metal binding site 1 [ion binding]; metal-binding site
1034807000214	putative 5' ssDNA interaction site; other site
1034807000215	metal binding site 3; metal-binding site
1034807000216	metal binding site 2 [ion binding]; metal-binding site
1034807000217	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1034807000218	putative DNA binding site [nucleotide binding]; other site
1034807000219	putative metal binding site [ion binding]; other site
1034807000220	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
1034807000221	active site
1034807000222	catalytic site [active]
1034807000223	substrate binding site [chemical binding]; other site
1034807000224	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1034807000225	active site
1034807000226	DNA binding site [nucleotide binding]
1034807000227	catalytic site [active]
1034807000228	Protein of unknown function (DUF1493); Region: DUF1493; pfam07377
1034807000229	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034807000230	Coenzyme A binding pocket [chemical binding]; other site
1034807000231	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1034807000232	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_e; cd04192
1034807000233	penicillin-binding protein 1C; Region: PBP_1c; TIGR02073
1034807000234	Transglycosylase; Region: Transgly; pfam00912
1034807000235	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1034807000236	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
1034807000237	Na+/H+ antiporter 1; Region: Na_H_antiport_1; cl01133
1034807000238	O-Antigen ligase; Region: Wzy_C; pfam04932
1034807000239	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1034807000240	UDP-glucuronate decarboxylase (UGD) and related proteins, extended (e) SDRs; Region: UGD_SDR_e; cd05230
1034807000241	NAD binding site [chemical binding]; other site
1034807000242	putative substrate binding site 2 [chemical binding]; other site
1034807000243	putative substrate binding site 1 [chemical binding]; other site
1034807000244	active site
1034807000245	Undecaprenyl-phosphate glucose phosphotransferase; Region: WcaJ_sugtrans; TIGR03023
1034807000246	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1034807000247	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1034807000248	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
1034807000249	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
1034807000250	MG2 domain; Region: A2M_N; pfam01835
1034807000251	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
1034807000252	surface patch; other site
1034807000253	thioester region; other site
1034807000254	specificity defining residues; other site
1034807000255	Succinate:quinone oxidoreductase (SQR)-like Type B subfamily 2, transmembrane subunit; composed of proteins with similarity to the SQRs of Geobacter metallireducens and Corynebacterium glutamicum. SQR catalyzes the oxidation of succinate to fumarate...; Region: SQR_TypeB_2_TM; cd03498
1034807000256	succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; Region: sdhC_b558_fam; TIGR02046
1034807000257	proximal heme binding site [chemical binding]; other site
1034807000258	distal heme binding site [chemical binding]; other site
1034807000259	putative dimer interface [polypeptide binding]; other site
1034807000260	putative Iron-sulfur protein interface [polypeptide binding]; other site
1034807000261	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK07573
1034807000262	L-aspartate oxidase; Provisional; Region: PRK06175
1034807000263	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1034807000264	succinate dehydrogenase/fumarate reductase iron-sulfur subunit; Validated; Region: PRK07570
1034807000265	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1034807000266	Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668
1034807000267	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034807000268	sequence-specific DNA binding site [nucleotide binding]; other site
1034807000269	salt bridge; other site
1034807000270	acyl-CoA synthetase; Validated; Region: PRK08162
1034807000271	Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles and Arabidopsis; Region: ttLC_FACS_AEE21_like; cd12118
1034807000272	acyl-activating enzyme (AAE) consensus motif; other site
1034807000273	putative active site [active]
1034807000274	AMP binding site [chemical binding]; other site
1034807000275	putative CoA binding site [chemical binding]; other site
1034807000276	Transposase [DNA replication, recombination, and repair]; Region: COG5421
1034807000277	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034807000278	AAA domain; Region: AAA_23; pfam13476
1034807000279	Walker A/P-loop; other site
1034807000280	ATP binding site [chemical binding]; other site
1034807000281	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034807000282	Walker B; other site
1034807000283	D-loop; other site
1034807000284	H-loop/switch region; other site
1034807000285	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
1034807000286	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
1034807000287	N-terminal putative catalytic domain of uncharacterized HKD family nucleases fused to putative helicases from the Snf2-like family; Region: PLDc_N_Snf2_like; cd09178
1034807000288	PLD-like domain; Region: PLDc_2; pfam13091
1034807000289	putative homodimer interface [polypeptide binding]; other site
1034807000290	putative active site [active]
1034807000291	catalytic site [active]
1034807000292	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1034807000293	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1034807000294	ATP binding site [chemical binding]; other site
1034807000295	putative Mg++ binding site [ion binding]; other site
1034807000296	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
1034807000297	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1034807000298	nucleotide binding region [chemical binding]; other site
1034807000299	ATP-binding site [chemical binding]; other site
1034807000300	DNA-binding protein, histone-like, putative; Region: HU_rel; TIGR01201
1034807000301	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1034807000302	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1034807000303	Nucleoside H+ symporter; Region: Nuc_H_symport; pfam03825
1034807000304	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034807000305	putative substrate translocation pore; other site
1034807000306	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
1034807000307	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
1034807000308	putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834
1034807000309	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
1034807000310	Gluconate 2-dehydrogenase subunit 3; Region: Gluconate_2-dh3; pfam13618
1034807000311	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
1034807000312	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1034807000313	AP endonuclease family 2 C terminus; Region: AP_endonuc_2_N; pfam07582
1034807000314	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
1034807000315	active site
1034807000316	DNA polymerase IV; Validated; Region: PRK02406
1034807000317	DNA binding site [nucleotide binding]
1034807000318	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS_aspartate_rich; cd04823
1034807000319	dimer interface [polypeptide binding]; other site
1034807000320	allosteric magnesium binding site [ion binding]; other site
1034807000321	active site
1034807000322	aspartate-rich active site metal binding site; other site
1034807000323	Schiff base residues; other site
1034807000324	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034807000325	non-specific DNA binding site [nucleotide binding]; other site
1034807000326	salt bridge; other site
1034807000327	sequence-specific DNA binding site [nucleotide binding]; other site
1034807000328	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034807000329	Walker A/P-loop; other site
1034807000330	ATP binding site [chemical binding]; other site
1034807000331	ABC transporter; Region: ABC_tran; pfam00005
1034807000332	Q-loop/lid; other site
1034807000333	ABC transporter signature motif; other site
1034807000334	Walker B; other site
1034807000335	D-loop; other site
1034807000336	Uncharacterized bacterial subgroup of the DEDDy 3'-5' exonuclease domain of family-B DNA polymerases; Region: DNA_polB_like1_exo; cd05782
1034807000337	active site
1034807000338	catalytic site [active]
1034807000339	substrate binding site [chemical binding]; other site
1034807000340	Uncharacterized membrane protein, required for spore maturation in B.subtilis. [General function prediction only]; Region: SpmA; COG2715
1034807000341	Uncharacterized membrane protein [Function unknown]; Region: SpmB; COG0700
1034807000342	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
1034807000343	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1034807000344	FMN binding site [chemical binding]; other site
1034807000345	active site
1034807000346	catalytic residues [active]
1034807000347	substrate binding site [chemical binding]; other site
1034807000348	Transposase [DNA replication, recombination, and repair]; Region: COG5421
1034807000349	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1034807000350	core domain interface [polypeptide binding]; other site
1034807000351	delta subunit interface [polypeptide binding]; other site
1034807000352	epsilon subunit interface [polypeptide binding]; other site
1034807000353	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1034807000354	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1034807000355	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1034807000356	beta subunit interaction interface [polypeptide binding]; other site
1034807000357	Walker A motif; other site
1034807000358	ATP binding site [chemical binding]; other site
1034807000359	Walker B motif; other site
1034807000360	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1034807000361	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1034807000362	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
1034807000363	F0F1 ATP synthase subunit B; Provisional; Region: PRK14471
1034807000364	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1034807000365	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1034807000366	ATP synthase A chain; Region: ATP-synt_A; cl00413
1034807000367	Putative F0F1-ATPase subunit (ATPase_gene1); Region: ATPase_gene1; pfam09527
1034807000368	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
1034807000369	Integral membrane protein CcmA involved in cell shape determination [Cell envelope biogenesis, outer membrane]; Region: CcmA; COG1664
1034807000370	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1034807000371	Cytochrome c; Region: Cytochrom_C; cl11414
1034807000372	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
1034807000373	DNA polymerase III, delta' subunit; Region: holB; TIGR00678
1034807000374	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1034807000375	Membrane carboxypeptidase/penicillin-binding protein [Cell envelope biogenesis, outer membrane]; Region: MrcA; COG5009
1034807000376	Transglycosylase; Region: Transgly; pfam00912
1034807000377	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1034807000378	GldH lipoprotein; Region: GldH_lipo; pfam14109
1034807000379	PSP1 C-terminal conserved region; Region: PSP1; cl00770
1034807000380	Bleomycin binding protein (BLMA) and similar proteins; BLMA confers bleomycin (Bm) resistance by directly binding to Bm; Region: BLMA_like; cd08349
1034807000381	dimer interface [polypeptide binding]; other site
1034807000382	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1034807000383	ligand binding site [chemical binding]; other site
1034807000384	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
1034807000385	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
1034807000386	Predicted nuclease of restriction endonuclease-like fold [General    function prediction only]; Region: COG4804
1034807000387	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
1034807000388	active site
1034807000389	AIPR protein; Region: AIPR; pfam10592
1034807000390	Domain of unknown function (DUF4420); Region: DUF4420; pfam14390
1034807000391	Z1 domain; Region: Z1; pfam10593
1034807000392	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c_3; pfam13589
1034807000393	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
1034807000394	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1034807000395	cofactor binding site; other site
1034807000396	DNA binding site [nucleotide binding]
1034807000397	substrate interaction site [chemical binding]; other site
1034807000398	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1034807000399	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034807000400	non-specific DNA binding site [nucleotide binding]; other site
1034807000401	salt bridge; other site
1034807000402	sequence-specific DNA binding site [nucleotide binding]; other site
1034807000403	SurA N-terminal domain; Region: SurA_N_3; cl07813
1034807000404	PPIC-type PPIASE domain; Region: Rotamase_3; pfam13616
1034807000405	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1034807000406	Domain of unknown function DUF21; Region: DUF21; pfam01595
1034807000407	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1034807000408	Transporter associated domain; Region: CorC_HlyC; smart01091
1034807000409	Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835
1034807000410	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1034807000411	binding surface
1034807000412	pantothenate kinase; Reviewed; Region: PRK13320
1034807000413	Phosphoglycerate kinase; Region: PGK; pfam00162
1034807000414	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
1034807000415	substrate binding site [chemical binding]; other site
1034807000416	hinge regions; other site
1034807000417	ADP binding site [chemical binding]; other site
1034807000418	catalytic site [active]
1034807000419	membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783
1034807000420	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1034807000421	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1034807000422	catalytic residue [active]
1034807000423	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034807000424	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034807000425	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034807000426	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034807000427	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1034807000428	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034807000429	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034807000430	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1034807000431	Cys/Met metabolism PLP-dependent enzyme; Region: Cys_Met_Meta_PP; pfam01053
1034807000432	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1034807000433	homodimer interface [polypeptide binding]; other site
1034807000434	substrate-cofactor binding pocket; other site
1034807000435	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034807000436	catalytic residue [active]
1034807000437	CYTH-like Clostridium thermocellum TTM-like subgroup 1; Region: CYTH-like_CthTTM-like_1; cd07891
1034807000438	putative active site [active]
1034807000439	putative metal binding residues [ion binding]; other site
1034807000440	signature motif; other site
1034807000441	putative dimer interface [polypeptide binding]; other site
1034807000442	putative phosphate binding site [ion binding]; other site
1034807000443	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
1034807000444	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
1034807000445	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1034807000446	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1034807000447	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1034807000448	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1034807000449	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
1034807000450	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1034807000451	active site
1034807000452	(T/H)XGH motif; other site
1034807000453	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
1034807000454	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1034807000455	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1034807000456	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1034807000457	dimer interface [polypeptide binding]; other site
1034807000458	ssDNA binding site [nucleotide binding]; other site
1034807000459	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1034807000460	gliding motility-associated protein GldE; Region: GldE; TIGR03520
1034807000461	Domain of unknown function DUF21; Region: DUF21; pfam01595
1034807000462	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1034807000463	Transporter associated domain; Region: CorC_HlyC; smart01091
1034807000464	gliding motility-associated lipoprotein GldD; Region: GldD_lipo; TIGR03512
1034807000465	rod shape-determining protein MreB; Provisional; Region: PRK13927
1034807000466	MreB and similar proteins; Region: MreB_like; cd10225
1034807000467	nucleotide binding site [chemical binding]; other site
1034807000468	Mg binding site [ion binding]; other site
1034807000469	putative protofilament interaction site [polypeptide binding]; other site
1034807000470	RodZ interaction site [polypeptide binding]; other site
1034807000471	rod shape-determining protein MreC; Provisional; Region: PRK13922
1034807000472	rod shape-determining protein MreC; Region: MreC; pfam04085
1034807000473	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
1034807000474	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1034807000475	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1034807000476	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
1034807000477	Glycosyltransferase (GlcNAc); Region: GlcNAc; pfam11397
1034807000478	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1034807000479	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1034807000480	Walker A/P-loop; other site
1034807000481	ATP binding site [chemical binding]; other site
1034807000482	Q-loop/lid; other site
1034807000483	ABC transporter signature motif; other site
1034807000484	Walker B; other site
1034807000485	D-loop; other site
1034807000486	H-loop/switch region; other site
1034807000487	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
1034807000488	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1034807000489	active site
1034807000490	dimer interface [polypeptide binding]; other site
1034807000491	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1034807000492	dimer interface [polypeptide binding]; other site
1034807000493	active site
1034807000494	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1034807000495	23S rRNA interface [nucleotide binding]; other site
1034807000496	L3 interface [polypeptide binding]; other site
1034807000497	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1034807000498	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1034807000499	rRNA interaction site [nucleotide binding]; other site
1034807000500	S8 interaction site; other site
1034807000501	putative laminin-1 binding site; other site
1034807000502	elongation factor Ts; Provisional; Region: tsf; PRK09377
1034807000503	UBA/TS-N domain; Region: UBA; pfam00627
1034807000504	Elongation factor TS; Region: EF_TS; pfam00889
1034807000505	Elongation factor TS; Region: EF_TS; pfam00889
1034807000506	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it, thus inhibiting its potentially lethal RNase activity inside the...; Region: Barstar_like; cl01048
1034807000507	RNAase interaction site [polypeptide binding]; other site
1034807000508	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
1034807000509	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
1034807000510	purine monophosphate binding site [chemical binding]; other site
1034807000511	dimer interface [polypeptide binding]; other site
1034807000512	putative catalytic residues [active]
1034807000513	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
1034807000514	4-hydroxyphenylpyruvate dioxygenase; Region: 4HPPD; TIGR01263
1034807000515	N-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HPPD) and hydroxymandelate Synthase (HmaS); Region: HPPD_N_like; cd08342
1034807000516	dimer interface [polypeptide binding]; other site
1034807000517	C-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HppD) and hydroxymandelate Synthase (HmaS); Region: HPPD_C_like; cd07250
1034807000518	active site
1034807000519	Fe binding site [ion binding]; other site
1034807000520	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1034807000521	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1034807000522	homogentisate 1,2-dioxygenase; Region: HgmA; cl17306
1034807000523	amino acid transporter; Region: 2A0306; TIGR00909
1034807000524	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
1034807000525	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
1034807000526	Patatin-like phospholipase domain containing protein 6, protein 7, and fungal NTE1; Region: Pat_PNPLA6_PNPLA7_NTE1_like; cd07205
1034807000527	active site
1034807000528	nucleophile elbow; other site
1034807000529	Surface antigen; Region: Bac_surface_Ag; pfam01103
1034807000530	Peptidase M1 family containing bacterial Aminopeptidase N; Region: M1_APN_5; cd09604
1034807000531	Zn binding site [ion binding]; other site
1034807000532	Protein of unknown function (DUF2167); Region: DUF2167; cl01938
1034807000533	Transposase [DNA replication, recombination, and repair]; Region: COG5421
1034807000534	Plasmid stabilisation system protein; Region: Plasmid_stabil; pfam05016
1034807000535	PQQ-like domain; Region: PQQ_2; pfam13360
1034807000536	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
1034807000537	RNA/DNA hybrid binding site [nucleotide binding]; other site
1034807000538	active site
1034807000539	Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism]; Region: PurN; COG0299
1034807000540	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
1034807000541	active site
1034807000542	substrate binding site [chemical binding]; other site
1034807000543	cosubstrate binding site; other site
1034807000544	catalytic site [active]
1034807000545	acyl carrier protein; Provisional; Region: acpP; PRK00982
1034807000546	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
1034807000547	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1034807000548	dimer interface [polypeptide binding]; other site
1034807000549	active site
1034807000550	ribonuclease III, bacterial; Region: RNaseIII; TIGR02191
1034807000551	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1034807000552	dimerization interface [polypeptide binding]; other site
1034807000553	active site
1034807000554	metal binding site [ion binding]; metal-binding site
1034807000555	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1034807000556	dsRNA binding site [nucleotide binding]; other site
1034807000557	Pyruvate kinase [Carbohydrate transport and metabolism]; Region: PykF; COG0469
1034807000558	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
1034807000559	domain interfaces; other site
1034807000560	active site
1034807000561	Predicted membrane protein [Function unknown]; Region: COG2311
1034807000562	Protein of unknown function (DUF418); Region: DUF418; cl12135
1034807000563	Protein of unknown function (DUF418); Region: DUF418; pfam04235
1034807000564	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
1034807000565	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1034807000566	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034807000567	Coenzyme A binding pocket [chemical binding]; other site
1034807000568	Aspartokinases [Amino acid transport and metabolism]; Region: LysC; COG0527
1034807000569	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
1034807000570	nucleotide binding site [chemical binding]; other site
1034807000571	substrate binding site [chemical binding]; other site
1034807000572	Protein of unknown function DUF262; Region: DUF262; pfam03235
1034807000573	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1034807000574	active site
1034807000575	Adenine-specific methyltransferase EcoRI; Region: EcoRI_methylase; pfam13651
1034807000576	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1034807000577	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cl02931
1034807000578	ligand binding site [chemical binding]; other site
1034807000579	Predicted exporters of the RND superfamily [General function prediction only]; Region: COG1033
1034807000580	Protein export membrane protein; Region: SecD_SecF; cl14618
1034807000581	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1034807000582	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1034807000583	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1034807000584	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
1034807000585	Clp amino terminal domain; Region: Clp_N; pfam02861
1034807000586	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034807000587	Walker A motif; other site
1034807000588	ATP binding site [chemical binding]; other site
1034807000589	Walker B motif; other site
1034807000590	arginine finger; other site
1034807000591	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034807000592	Walker A motif; other site
1034807000593	ATP binding site [chemical binding]; other site
1034807000594	Walker B motif; other site
1034807000595	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1034807000596	ribonuclease P; Reviewed; Region: rnpA; PRK01903
1034807000597	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
1034807000598	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
1034807000599	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1034807000600	protein binding site [polypeptide binding]; other site
1034807000601	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1034807000602	Catalytic dyad [active]
1034807000603	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1034807000604	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1034807000605	ligand binding site [chemical binding]; other site
1034807000606	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1034807000607	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1034807000608	ligand binding site [chemical binding]; other site
1034807000609	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
1034807000610	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
1034807000611	Arsenate Reductase (ArsC) family; composed of TRX-fold arsenic reductases and similar proteins including the transcriptional regulator, Spx. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from...; Region: ArsC_family; cd02977
1034807000612	ArsC family; Region: ArsC; pfam03960
1034807000613	catalytic residue [active]
1034807000614	DinB superfamily; Region: DinB_2; pfam12867
1034807000615	Glycosyltransferase family 28 C-terminal domain; Region: Glyco_tran_28_C; cl17369
1034807000616	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034807000617	S-adenosylmethionine binding site [chemical binding]; other site
1034807000618	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1034807000619	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1034807000620	DNA binding site [nucleotide binding]
1034807000621	active site
1034807000622	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1034807000623	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1034807000624	RimM N-terminal domain; Region: RimM; pfam01782
1034807000625	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1034807000626	active site
1034807000627	Protein of unknown function (DUF4254); Region: DUF4254; pfam14063
1034807000628	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
1034807000629	PGAP1-like protein; Region: PGAP1; pfam07819
1034807000630	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807000631	Helix-turn-helix domain; Region: HTH_18; pfam12833
1034807000632	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1034807000633	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
1034807000634	Lumazine binding domain; Region: Lum_binding; pfam00677
1034807000635	Lumazine binding domain; Region: Lum_binding; pfam00677
1034807000636	4-hydroxythreonine-4-phosphate dehydrogenase; Region: pdxA; TIGR00557
1034807000637	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
1034807000638	Uncharacterized ACR, COG1399; Region: DUF177; pfam02620
1034807000639	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
1034807000640	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1034807000641	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1034807000642	dimer interface [polypeptide binding]; other site
1034807000643	active site
1034807000644	CoA binding pocket [chemical binding]; other site
1034807000645	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
1034807000646	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1034807000647	carboxyltransferase (CT) interaction site; other site
1034807000648	biotinylation site [posttranslational modification]; other site
1034807000649	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
1034807000650	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1034807000651	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1034807000652	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1034807000653	coproporphyrinogen III oxidase; Provisional; Region: PRK08599
1034807000654	HemN C-terminal domain; Region: HemN_C; pfam06969
1034807000655	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
1034807000656	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1034807000657	G1 box; other site
1034807000658	GTP/Mg2+ binding site [chemical binding]; other site
1034807000659	Switch I region; other site
1034807000660	G2 box; other site
1034807000661	G3 box; other site
1034807000662	Switch II region; other site
1034807000663	G4 box; other site
1034807000664	G5 box; other site
1034807000665	Nucleoside recognition; Region: Gate; pfam07670
1034807000666	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
1034807000667	Nucleoside recognition; Region: Gate; pfam07670
1034807000668	FeoA domain; Region: FeoA; pfam04023
1034807000669	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1034807000670	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1034807000671	putative acyl-acceptor binding pocket; other site
1034807000672	Acyl ACP desaturase, ferritin-like diiron-binding domain; Region: Acyl_ACP_Desat; cd01050
1034807000673	Fatty acid desaturase; Region: FA_desaturase_2; pfam03405
1034807000674	homodimer interface [polypeptide binding]; other site
1034807000675	putative substrate binding pocket [chemical binding]; other site
1034807000676	diiron center [ion binding]; other site
1034807000677	pantoate--beta-alanine ligase; Region: panC; TIGR00018
1034807000678	Pantoate-beta-alanine ligase; Region: PanC; cd00560
1034807000679	active site
1034807000680	ATP-binding site [chemical binding]; other site
1034807000681	pantoate-binding site; other site
1034807000682	HXXH motif; other site
1034807000683	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
1034807000684	tetramerization interface [polypeptide binding]; other site
1034807000685	active site
1034807000686	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
1034807000687	phenylacetate-CoA oxygenase/reductase, PaaK subunit; Region: PA_CoA_Oxy5; TIGR02160
1034807000688	NAD(P) binding domain of ferredoxin reductase like phenylacetic acid (PA) degradation oxidoreductase. PA oxidoreductases of E. coli hydroxylate PA-CoA in the second step of PA degradation. Members of this group typically fuse a ferredoxin reductase-like...; Region: PA_degradation_oxidoreductase_like; cd06214
1034807000689	FAD binding pocket [chemical binding]; other site
1034807000690	FAD binding motif [chemical binding]; other site
1034807000691	phosphate binding motif [ion binding]; other site
1034807000692	beta-alpha-beta structure motif; other site
1034807000693	NAD(p) ribose binding residues [chemical binding]; other site
1034807000694	NAD binding pocket [chemical binding]; other site
1034807000695	NAD(P)-pyrophosphate-nicotinamide binding residues [chemical binding]; other site
1034807000696	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1034807000697	catalytic loop [active]
1034807000698	iron binding site [ion binding]; other site
1034807000699	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
1034807000700	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1034807000701	Ribosome-binding factor A; Region: RBFA; pfam02033
1034807000702	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
1034807000703	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
1034807000704	TPP-binding site [chemical binding]; other site
1034807000705	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
1034807000706	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
1034807000707	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1034807000708	E3 interaction surface; other site
1034807000709	lipoyl attachment site [posttranslational modification]; other site
1034807000710	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1034807000711	putative oxidoreductase; Provisional; Region: PRK11579
1034807000712	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1034807000713	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1034807000714	Nicotinamide mononucleotide transporter; Region: NMN_transporter; pfam04973
1034807000715	AAA domain; Region: AAA_28; pfam13521
1034807000716	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
1034807000717	Domain of unknown function (DUF4301); Region: DUF4301; pfam14134
1034807000718	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1034807000719	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
1034807000720	Peptidase S8 family domain in Subtilisin_Novo-like proteins; Region: Peptidases_S8_Subtilisin_Novo-like; cd07483
1034807000721	active site
1034807000722	catalytic triad [active]
1034807000723	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
1034807000724	nucleotide binding site/active site [active]
1034807000725	HIT family signature motif; other site
1034807000726	catalytic residue [active]
1034807000727	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1034807000728	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1034807000729	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1034807000730	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
1034807000731	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1034807000732	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1034807000733	DNA binding site [nucleotide binding]
1034807000734	domain linker motif; other site
1034807000735	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1034807000736	dimerization interface [polypeptide binding]; other site
1034807000737	ligand binding site [chemical binding]; other site
1034807000738	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
1034807000739	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
1034807000740	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1034807000741	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1034807000742	putative active site [active]
1034807000743	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1034807000744	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1034807000745	substrate binding pocket [chemical binding]; other site
1034807000746	chain length determination region; other site
1034807000747	substrate-Mg2+ binding site; other site
1034807000748	catalytic residues [active]
1034807000749	aspartate-rich region 1; other site
1034807000750	active site lid residues [active]
1034807000751	aspartate-rich region 2; other site
1034807000752	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
1034807000753	putative catalytic site [active]
1034807000754	putative phosphate binding site [ion binding]; other site
1034807000755	fumarate hydratase; Provisional; Region: PRK15389
1034807000756	Fumarate hydratase (Fumerase); Region: Fumerase; pfam05681
1034807000757	Fumarase C-terminus; Region: Fumerase_C; pfam05683
1034807000758	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1034807000759	Methylmalonyl-CoA epimerase (MMCE); Region: MMCE; cd07249
1034807000760	dimer interface [polypeptide binding]; other site
1034807000761	substrate binding site [chemical binding]; other site
1034807000762	metal binding site [ion binding]; metal-binding site
1034807000763	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1034807000764	Ligand Binding Site [chemical binding]; other site
1034807000765	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1034807000766	Ligand Binding Site [chemical binding]; other site
1034807000767	hypothetical protein; Validated; Region: PRK02001
1034807000768	heptamer interface [polypeptide binding]; other site
1034807000769	Sm1 motif; other site
1034807000770	hexamer interface [polypeptide binding]; other site
1034807000771	RNA binding site [nucleotide binding]; other site
1034807000772	Sm2 motif; other site
1034807000773	transcription termination factor NusA; Region: NusA; TIGR01953
1034807000774	NusA N-terminal domain; Region: NusA_N; pfam08529
1034807000775	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1034807000776	RNA binding site [nucleotide binding]; other site
1034807000777	homodimer interface [polypeptide binding]; other site
1034807000778	NusA-like KH domain; Region: KH_5; pfam13184
1034807000779	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1034807000780	G-X-X-G motif; other site
1034807000781	translation initiation factor IF-2; Region: IF-2; TIGR00487
1034807000782	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1034807000783	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1034807000784	G1 box; other site
1034807000785	putative GEF interaction site [polypeptide binding]; other site
1034807000786	GTP/Mg2+ binding site [chemical binding]; other site
1034807000787	Switch I region; other site
1034807000788	G2 box; other site
1034807000789	G3 box; other site
1034807000790	Switch II region; other site
1034807000791	G4 box; other site
1034807000792	G5 box; other site
1034807000793	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1034807000794	Translation-initiation factor 2; Region: IF-2; pfam11987
1034807000795	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1034807000796	Sporulation related domain; Region: SPOR; cl10051
1034807000797	Cytochrome c; Region: Cytochrom_C; pfam00034
1034807000798	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
1034807000799	Nucleopolyhedrovirus protein of unknown function (DUF912); Region: DUF912; pfam06024
1034807000800	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
1034807000801	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1034807000802	Heme-binding domain of the class III cytochrome C family and related proteins; Region: Cytochrom_C3; cd08168
1034807000803	heme-binding residues [chemical binding]; other site
1034807000804	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1034807000805	molybdopterin cofactor binding site; other site
1034807000806	The MopB_CT_PHLH CD includes a group of related uncharacterized putative hydrogenase-like homologs (PHLH) of molybdopterin binding proteins. This CD is of the PHLH region homologous to the conserved molybdopterin-binding C-terminal (MopB_CT) region...; Region: MopB_CT_PHLH; cd02784
1034807000807	4Fe-4S binding domain; Region: Fer4; cl02805
1034807000808	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
1034807000809	Polysulphide reductase [Energy production and conversion]; Region: COG5557; cl17901
1034807000810	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
1034807000811	Protein of unknown function (DUF3341); Region: DUF3341; pfam11821
1034807000812	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
1034807000813	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
1034807000814	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
1034807000815	Heme/copper-type cytochrome/quinol oxidases, subunit 2 [Energy production and conversion]; Region: CyoA; COG1622
1034807000816	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
1034807000817	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
1034807000818	cytochrome c oxidase, subunit I; Region: CtaD_CoxA; TIGR02891
1034807000819	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1034807000820	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034807000821	Walker A motif; other site
1034807000822	ATP binding site [chemical binding]; other site
1034807000823	Walker B motif; other site
1034807000824	arginine finger; other site
1034807000825	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1034807000826	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
1034807000827	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
1034807000828	Protein of unknown function (DUF2723); Region: DUF2723; pfam11028
1034807000829	Helix-turn-helix domain; Region: HTH_18; pfam12833
1034807000830	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1034807000831	Hexameric tyrosine-coordinated heme protein (HTHP); Region: HTHP; pfam11534
1034807000832	Protein of unknown function (DUF3050); Region: DUF3050; pfam11251
1034807000833	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1034807000834	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
1034807000835	active site
1034807000836	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
1034807000837	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1034807000838	putative active site [active]
1034807000839	putative metal binding site [ion binding]; other site
1034807000840	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
1034807000841	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1034807000842	dimer interface [polypeptide binding]; other site
1034807000843	putative anticodon binding site; other site
1034807000844	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1034807000845	motif 1; other site
1034807000846	active site
1034807000847	motif 2; other site
1034807000848	motif 3; other site
1034807000849	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034807000850	AAA domain; Region: AAA_17; cl17253
1034807000851	AAA domain; Region: AAA_21; pfam13304
1034807000852	Walker A/P-loop; other site
1034807000853	ATP binding site [chemical binding]; other site
1034807000854	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
1034807000855	Phosphoglyceromutase [Carbohydrate transport and metabolism]; Region: GpmI; COG0696
1034807000856	phosphoglyceromutase; Provisional; Region: PRK05434
1034807000857	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
1034807000858	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
1034807000859	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034807000860	S-adenosylmethionine binding site [chemical binding]; other site
1034807000861	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
1034807000862	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1034807000863	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cl00047
1034807000864	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
1034807000865	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1034807000866	PhoH-like protein; Region: PhoH; pfam02562
1034807000867	S-adenosyl-l-methionine hydroxide adenosyltransferase; Region: SAM_adeno_trans; pfam01887
1034807000868	Antibiotic biosynthesis monooxygenase; Region: ABM; pfam03992
1034807000869	isocitrate lyase; Provisional; Region: PRK15063
1034807000870	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
1034807000871	tetramer interface [polypeptide binding]; other site
1034807000872	active site
1034807000873	Mg2+/Mn2+ binding site [ion binding]; other site
1034807000874	malate synthase A; Region: malate_syn_A; TIGR01344
1034807000875	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
1034807000876	active site
1034807000877	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1034807000878	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034807000879	non-specific DNA binding site [nucleotide binding]; other site
1034807000880	salt bridge; other site
1034807000881	sequence-specific DNA binding site [nucleotide binding]; other site
1034807000882	Domain of unknown function (DUF955); Region: DUF955; pfam06114
1034807000883	DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases.  They exists as monomers and homodimers; Region: NUC; cd00091
1034807000884	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
1034807000885	active site
1034807000886	substrate binding site [chemical binding]; other site
1034807000887	Mg2+ binding site [ion binding]; other site
1034807000888	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
1034807000889	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
1034807000890	ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274
1034807000891	Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296
1034807000892	putative active site [active]
1034807000893	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1034807000894	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034807000895	Walker A/P-loop; other site
1034807000896	ATP binding site [chemical binding]; other site
1034807000897	Q-loop/lid; other site
1034807000898	ABC transporter signature motif; other site
1034807000899	Walker B; other site
1034807000900	D-loop; other site
1034807000901	H-loop/switch region; other site
1034807000902	radical SAM/SPASM domain Clo7bot peptide maturase; Region: rSAM_Clo7bot; TIGR04334
1034807000903	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1034807000904	FeS/SAM binding site; other site
1034807000905	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1034807000906	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1034807000907	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1034807000908	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1034807000909	Salmonella virulence plasmid 65kDa B protein; Region: SpvB; pfam03534
1034807000910	Family description; Region: VCBS; pfam13517
1034807000911	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1034807000912	Possible hemagglutinin (DUF637); Region: DUF637; pfam04830
1034807000913	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
1034807000914	PhoU domain; Region: PhoU; pfam01895
1034807000915	PhoU domain; Region: PhoU; pfam01895
1034807000916	ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PstB; COG1117
1034807000917	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1034807000918	Walker A/P-loop; other site
1034807000919	ATP binding site [chemical binding]; other site
1034807000920	Q-loop/lid; other site
1034807000921	ABC transporter signature motif; other site
1034807000922	Walker B; other site
1034807000923	D-loop; other site
1034807000924	H-loop/switch region; other site
1034807000925	phosphate ABC transporter, permease protein PstA; Region: 3a0107s02c; TIGR00974
1034807000926	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034807000927	dimer interface [polypeptide binding]; other site
1034807000928	conserved gate region; other site
1034807000929	putative PBP binding loops; other site
1034807000930	ABC-ATPase subunit interface; other site
1034807000931	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
1034807000932	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1034807000933	dimer interface [polypeptide binding]; other site
1034807000934	conserved gate region; other site
1034807000935	putative PBP binding loops; other site
1034807000936	ABC-ATPase subunit interface; other site
1034807000937	PBP superfamily domain; Region: PBP_like_2; cl17296
1034807000938	Phosphate-selective porin O and P; Region: Porin_O_P; pfam07396
1034807000939	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1034807000940	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034807000941	active site
1034807000942	phosphorylation site [posttranslational modification]
1034807000943	intermolecular recognition site; other site
1034807000944	dimerization interface [polypeptide binding]; other site
1034807000945	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1034807000946	DNA binding site [nucleotide binding]
1034807000947	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1034807000948	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1034807000949	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1034807000950	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1034807000951	putative recombination protein RecB; Provisional; Region: PRK13909
1034807000952	Family description; Region: UvrD_C_2; pfam13538
1034807000953	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1034807000954	8-amino-7-oxononanoate synthase; Reviewed; Region: PRK05958
1034807000955	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1034807000956	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1034807000957	catalytic residue [active]
1034807000958	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1034807000959	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1034807000960	active site
1034807000961	HIGH motif; other site
1034807000962	dimer interface [polypeptide binding]; other site
1034807000963	KMSKS motif; other site
1034807000964	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1034807000965	Catalytic NodB homology domain of rhizobial NodB-like proteins; Region: CE4_NodB_like_6s_7s; cd10917
1034807000966	NodB motif; other site
1034807000967	active site
1034807000968	catalytic site [active]
1034807000969	metal binding site [ion binding]; metal-binding site
1034807000970	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
1034807000971	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1034807000972	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1034807000973	protein binding site [polypeptide binding]; other site
1034807000974	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
1034807000975	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1034807000976	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1034807000977	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1034807000978	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1034807000979	YceG-like family; Region: YceG; pfam02618
1034807000980	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1034807000981	dimerization interface [polypeptide binding]; other site
1034807000982	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
1034807000983	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1034807000984	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1034807000985	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1034807000986	catalytic triad [active]
1034807000987	Tunnelling fold (T-fold). The five known T-folds are found in five different enzymes with different functions: dihydroneopterin-triphosphate epimerase (DHNTPE), dihydroneopterin aldolase (DHNA) , GTP cyclohydrolase I (GTPCH-1),  6-pyrovoyl...; Region: TFold; cl00263
1034807000988	active site
1034807000989	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
1034807000990	isopentenyl-diphosphate delta-isomerase, type 1; Region: IPP_isom_1; TIGR02150
1034807000991	active site
1034807000992	metal binding site [ion binding]; metal-binding site
1034807000993	nudix motif; other site
1034807000994	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229; cl15841
1034807000995	bifunctional methionine sulfoxide reductase B/A protein; Provisional; Region: PRK05550
1034807000996	methionine sulfoxide reductase A; Provisional; Region: PRK14054
1034807000997	SMI1 / KNR4 family; Region: SMI1_KNR4; smart00860
1034807000998	hypothetical protein; Provisional; Region: PRK08201
1034807000999	Uncharacterized M20 Dipeptidases; Region: M20_dipept_like_3; cd05680
1034807001000	metal binding site [ion binding]; metal-binding site
1034807001001	putative dimer interface [polypeptide binding]; other site
1034807001002	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1034807001003	MiaB-like tRNA modifying enzyme; Region: MiaB-like-C; TIGR01579
1034807001004	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1034807001005	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1034807001006	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1034807001007	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1034807001008	catalytic residue [active]
1034807001009	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
1034807001010	classical (c) SDRs; Region: SDR_c; cd05233
1034807001011	NAD(P) binding site [chemical binding]; other site
1034807001012	active site
1034807001013	Predicted unusual protein kinase [General function prediction only]; Region: AarF; COG0661
1034807001014	ABC1 family; Region: ABC1; cl17513
1034807001015	Class II hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR); Region: HMG-CoA_reductase_classII; cd00644
1034807001016	homodimer interface [polypeptide binding]; other site
1034807001017	catalytic residues [active]
1034807001018	NAD binding site [chemical binding]; other site
1034807001019	substrate binding pocket [chemical binding]; other site
1034807001020	flexible flap; other site
1034807001021	germination protein, Ger(x)C family; Region: spore_ger_x_C; TIGR02887
1034807001022	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
1034807001023	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1034807001024	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034807001025	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1034807001026	putative substrate translocation pore; other site
1034807001027	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
1034807001028	putative active site [active]
1034807001029	putative metal binding site [ion binding]; other site
1034807001030	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
1034807001031	dimer interface [polypeptide binding]; other site
1034807001032	catalytic triad [active]
1034807001033	CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; Region: CUB; cd00041
1034807001034	heterodimerization interface [polypeptide binding]; other site
1034807001035	CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; Region: CUB; cd00041
1034807001036	heterodimerization interface [polypeptide binding]; other site
1034807001037	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1034807001038	Interdomain contacts; other site
1034807001039	Cytokine receptor motif; other site
1034807001040	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
1034807001041	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
1034807001042	TPR repeat; Region: TPR_11; pfam13414
1034807001043	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1034807001044	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1034807001045	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1034807001046	ligand binding site [chemical binding]; other site
1034807001047	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
1034807001048	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1034807001049	NAD binding site [chemical binding]; other site
1034807001050	homodimer interface [polypeptide binding]; other site
1034807001051	active site
1034807001052	substrate binding site [chemical binding]; other site
1034807001053	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1034807001054	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1034807001055	inhibitor-cofactor binding pocket; inhibition site
1034807001056	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034807001057	catalytic residue [active]
1034807001058	3-deoxy-D-manno-octulosonic-acid transferase [Cell envelope biogenesis, outer membrane]; Region: KdtA; COG1519
1034807001059	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
1034807001060	Peptidase S46; Region: Peptidase_S46; pfam10459
1034807001061	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1034807001062	Domain of unknown function (DUF1508); Region: DUF1508; cl01356
1034807001063	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
1034807001064	MutS domain I; Region: MutS_I; pfam01624
1034807001065	MutS domain II; Region: MutS_II; pfam05188
1034807001066	MutS domain III; Region: MutS_III; pfam05192
1034807001067	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
1034807001068	Walker A/P-loop; other site
1034807001069	ATP binding site [chemical binding]; other site
1034807001070	Q-loop/lid; other site
1034807001071	ABC transporter signature motif; other site
1034807001072	Walker B; other site
1034807001073	D-loop; other site
1034807001074	H-loop/switch region; other site
1034807001075	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
1034807001076	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1034807001077	Protein of unknown function (DUF3997); Region: DUF3997; pfam13162
1034807001078	Domain of unknown function (DUF4403); Region: DUF4403; pfam14356
1034807001079	Outer membrane efflux protein; Region: OEP; pfam02321
1034807001080	Outer membrane efflux protein; Region: OEP; pfam02321
1034807001081	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1034807001082	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1034807001083	HlyD family secretion protein; Region: HlyD_3; pfam13437
1034807001084	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1034807001085	Glycoprotease family; Region: Peptidase_M22; pfam00814
1034807001086	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
1034807001087	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034807001088	putative substrate translocation pore; other site
1034807001089	POT family; Region: PTR2; cl17359
1034807001090	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
1034807001091	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1034807001092	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1034807001093	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1034807001094	putative active site [active]
1034807001095	catalytic residue [active]
1034807001096	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1034807001097	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034807001098	active site
1034807001099	phosphorylation site [posttranslational modification]
1034807001100	intermolecular recognition site; other site
1034807001101	dimerization interface [polypeptide binding]; other site
1034807001102	LytTr DNA-binding domain; Region: LytTR; smart00850
1034807001103	Histidine kinase; Region: His_kinase; pfam06580
1034807001104	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
1034807001105	Mg2+ binding site [ion binding]; other site
1034807001106	G-X-G motif; other site
1034807001107	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1034807001108	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1034807001109	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
1034807001110	Protein of unknown function, DUF417; Region: DUF417; cl01162
1034807001111	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
1034807001112	active site
1034807001113	PAP2, haloperoxidase_like subfamily. Haloperoxidases catalyze the oxidation of halides such as bromide or chloride by hydrogen peroxide, which results in subsequent halogenation of organic substrates, or halide-assisted disproportionation of hydrogen...; Region: PAP2_haloperoxidase; cd03398
1034807001114	active site
1034807001115	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1034807001116	active site
1034807001117	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1034807001118	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
1034807001119	putative acyl-acceptor binding pocket; other site
1034807001120	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
1034807001121	active site
1034807001122	homodimer interface [polypeptide binding]; other site
1034807001123	Conserved TM helix; Region: TM_helix; pfam05552
1034807001124	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1034807001125	Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]; Region: COG1331
1034807001126	TRX domain, SSP411 protein family; members of this family are highly conserved proteins present in eukaryotes, bacteria and archaea, about 600-800 amino acids in length, which contain a TRX domain with a redox active CXXC motif. The human/rat protein; Region: SSP411; cd02955
1034807001127	catalytic residues [active]
1034807001128	META domain; Region: META; pfam03724
1034807001129	META domain; Region: META; pfam03724
1034807001130	META domain; Region: META; pfam03724
1034807001131	META domain; Region: META; pfam03724
1034807001132	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
1034807001133	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
1034807001134	trimer interface [polypeptide binding]; other site
1034807001135	putative metal binding site [ion binding]; other site
1034807001136	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
1034807001137	gliding motility-associated C-terminal domain; Region: Bac_Flav_CTERM; TIGR04131
1034807001138	Scaffold protein Nfu/NifU N terminal; Region: Nfu_N; pfam08712
1034807001139	Scaffold protein Nfu/NifU N terminal; Region: Nfu_N; pfam08712
1034807001140	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
1034807001141	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1034807001142	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1034807001143	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
1034807001144	catalytic center binding site [active]
1034807001145	ATP binding site [chemical binding]; other site
1034807001146	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
1034807001147	Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673
1034807001148	Substrate-binding site [chemical binding]; other site
1034807001149	Substrate specificity [chemical binding]; other site
1034807001150	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
1034807001151	Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673
1034807001152	Substrate-binding site [chemical binding]; other site
1034807001153	Substrate specificity [chemical binding]; other site
1034807001154	Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_like_4; cd04501
1034807001155	active site
1034807001156	catalytic triad [active]
1034807001157	oxyanion hole [active]
1034807001158	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1034807001159	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1034807001160	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
1034807001161	DNA binding residues [nucleotide binding]
1034807001162	TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; Region: SusC_RagA_signa; TIGR04057
1034807001163	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1034807001164	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1034807001165	HlyD family secretion protein; Region: HlyD_3; pfam13437
1034807001166	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1034807001167	Protein export membrane protein; Region: SecD_SecF; cl14618
1034807001168	Trans-2-enoyl-CoA reductase (TER) and 2,4-dienoyl-CoA reductase (DECR), atypical (a) SDR; Region: TER_DECR_SDR_a; cd05369
1034807001169	short chain dehydrogenase; Provisional; Region: PRK07677
1034807001170	NAD(P) binding site [chemical binding]; other site
1034807001171	substrate binding site [chemical binding]; other site
1034807001172	homotetramer interface [polypeptide binding]; other site
1034807001173	active site
1034807001174	homodimer interface [polypeptide binding]; other site
1034807001175	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
1034807001176	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1034807001177	active site
1034807001178	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1034807001179	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
1034807001180	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034807001181	ATP binding site [chemical binding]; other site
1034807001182	Walker B motif; other site
1034807001183	arginine finger; other site
1034807001184	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1034807001185	DnaA box-binding interface [nucleotide binding]; other site
1034807001186	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1034807001187	active site
1034807001188	Uncharacterized conserved protein [Function unknown]; Region: COG1739
1034807001189	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
1034807001190	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
1034807001191	?-D-glucose-1-phosphatase; Provisional; Region: PRK09456
1034807001192	riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326
1034807001193	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
1034807001194	catalytic motif [active]
1034807001195	Zn binding site [ion binding]; other site
1034807001196	RibD C-terminal domain; Region: RibD_C; pfam01872
1034807001197	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1034807001198	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034807001199	Coenzyme A binding pocket [chemical binding]; other site
1034807001200	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
1034807001201	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034807001202	S-adenosylmethionine binding site [chemical binding]; other site
1034807001203	Putative FMN-binding domain; Region: FMN_bind_2; pfam04299
1034807001204	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1034807001205	active site
1034807001206	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1034807001207	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1034807001208	DNA binding residues [nucleotide binding]
1034807001209	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK01096
1034807001210	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; smart00471
1034807001211	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
1034807001212	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
1034807001213	Competence protein; Region: Competence; pfam03772
1034807001214	Protein Disulfide Isomerase (PDIa) family, redox active TRX domains; composed of eukaryotic proteins involved in oxidative protein folding in the endoplasmic reticulum (ER) by acting as catalysts and folding assistants. Members of this family include PDI...; Region: PDI_a_family; cd02961
1034807001215	catalytic residues [active]
1034807001216	Peptidase C10 family; Region: Peptidase_C10; pfam01640
1034807001217	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
1034807001218	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1034807001219	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1034807001220	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1034807001221	active site
1034807001222	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
1034807001223	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1034807001224	5S rRNA interface [nucleotide binding]; other site
1034807001225	CTC domain interface [polypeptide binding]; other site
1034807001226	L16 interface [polypeptide binding]; other site
1034807001227	maltose O-acetyltransferase; Provisional; Region: PRK10092
1034807001228	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
1034807001229	active site
1034807001230	substrate binding site [chemical binding]; other site
1034807001231	trimer interface [polypeptide binding]; other site
1034807001232	CoA binding site [chemical binding]; other site
1034807001233	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1034807001234	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1034807001235	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1034807001236	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1034807001237	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1034807001238	Flavin containing amine oxidoreductase; Region: Amino_oxidase; pfam01593
1034807001239	spermidine synthase; Provisional; Region: PRK03612
1034807001240	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034807001241	S-adenosylmethionine binding site [chemical binding]; other site
1034807001242	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
1034807001243	Domain of unknown function (DUF4178); Region: DUF4178; pfam13785
1034807001244	S-adenosylmethionine decarboxylase; Region: AdoMet_dc; cl00687
1034807001245	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1034807001246	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1034807001247	DNA binding site [nucleotide binding]
1034807001248	domain linker motif; other site
1034807001249	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1034807001250	dimerization interface [polypeptide binding]; other site
1034807001251	ligand binding site [chemical binding]; other site
1034807001252	N-terminal Early set domain associated with the catalytic domain of isoamylase-like (also called glycogen 6-glucanohydrolase) proteins; Region: E_set_Isoamylase_like_N; cd07184
1034807001253	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1034807001254	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1034807001255	folate binding site [chemical binding]; other site
1034807001256	NADP+ binding site [chemical binding]; other site
1034807001257	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1034807001258	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
1034807001259	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1034807001260	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1034807001261	starch binding outer membrane protein SusD; Region: SusD; cl17845
1034807001262	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
1034807001263	SusD family; Region: SusD; pfam07980
1034807001264	Family description; Region: VCBS; pfam13517
1034807001265	Family description; Region: VCBS; pfam13517
1034807001266	Family description; Region: VCBS; pfam13517
1034807001267	Family description; Region: VCBS; pfam13517
1034807001268	ASPIC and UnbV; Region: UnbV_ASPIC; pfam07593
1034807001269	Family description; Region: VCBS; pfam13517
1034807001270	Family description; Region: VCBS; pfam13517
1034807001271	Family description; Region: VCBS; pfam13517
1034807001272	Family description; Region: VCBS; pfam13517
1034807001273	Family description; Region: VCBS; pfam13517
1034807001274	Family description; Region: VCBS; pfam13517
1034807001275	ASPIC and UnbV; Region: UnbV_ASPIC; pfam07593
1034807001276	Family description; Region: VCBS; pfam13517
1034807001277	Family description; Region: VCBS; pfam13517
1034807001278	Family description; Region: VCBS; pfam13517
1034807001279	PAP2, haloperoxidase_like subfamily. Haloperoxidases catalyze the oxidation of halides such as bromide or chloride by hydrogen peroxide, which results in subsequent halogenation of organic substrates, or halide-assisted disproportionation of hydrogen...; Region: PAP2_haloperoxidase; cd03398
1034807001280	active site
1034807001281	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
1034807001282	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034807001283	putative substrate translocation pore; other site
1034807001284	MFS/sugar transport protein; Region: MFS_2; pfam13347
1034807001285	Glucoamylase and related glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: SGA1; COG3387
1034807001286	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1034807001287	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1034807001288	substrate binding site [chemical binding]; other site
1034807001289	ATP binding site [chemical binding]; other site
1034807001290	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
1034807001291	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
1034807001292	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1034807001293	Surface antigen; Region: Bac_surface_Ag; pfam01103
1034807001294	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1034807001295	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
1034807001296	active site
1034807001297	intersubunit interface [polypeptide binding]; other site
1034807001298	zinc binding site [ion binding]; other site
1034807001299	Na+ binding site [ion binding]; other site
1034807001300	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
1034807001301	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1034807001302	Protein of unknown function (DUF3109); Region: DUF3109; pfam11307
1034807001303	Domain of unknown function DUF59; Region: DUF59; pfam01883
1034807001304	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Mrp; COG0489
1034807001305	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1034807001306	Walker A motif; other site
1034807001307	NifU-like domain; Region: NifU; cl00484
1034807001308	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cl00159
1034807001309	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
1034807001310	Delta(1)-pyrroline-5-carboxylate dehydrogenase, ALDH families 4 and 17; Region: ALDH_F4-17_P5CDH; cd07123
1034807001311	delta-1-pyrroline-5-carboxylate dehydrogenase, group 1; Region: D1pyr5carbox1; TIGR01236
1034807001312	Glutamate binding site [chemical binding]; other site
1034807001313	NAD binding site [chemical binding]; other site
1034807001314	catalytic residues [active]
1034807001315	3-hydroxyanthranilic acid dioxygenase; Region: 3-HAO; cl17399
1034807001316	aldehyde dehydrogenase family 7 member; Region: PLN02315
1034807001317	NAD+-dependent alpha-aminoadipic semialdehyde dehydrogenase, ALDH family members 7A1 and 7B; Region: ALDH_F7_AASADH; cd07130
1034807001318	tetrameric interface [polypeptide binding]; other site
1034807001319	NAD binding site [chemical binding]; other site
1034807001320	catalytic residues [active]
1034807001321	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
1034807001322	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
1034807001323	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1034807001324	PBP superfamily domain; Region: PBP_like_2; pfam12849
1034807001325	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
1034807001326	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034807001327	binding surface
1034807001328	TPR motif; other site
1034807001329	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1034807001330	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1034807001331	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034807001332	S-adenosylmethionine binding site [chemical binding]; other site
1034807001333	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1034807001334	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1034807001335	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1034807001336	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
1034807001337	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
1034807001338	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
1034807001339	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
1034807001340	active site residue [active]
1034807001341	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
1034807001342	active site residue [active]
1034807001343	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
1034807001344	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
1034807001345	mTERF; Region: mTERF; pfam02536
1034807001346	short chain dehydrogenase; Provisional; Region: PRK12828
1034807001347	classical (c) SDRs; Region: SDR_c; cd05233
1034807001348	NAD(P) binding site [chemical binding]; other site
1034807001349	active site
1034807001350	SprT homologues; Region: SprT; cl01182
1034807001351	Mannose-1-phosphate guanylyltransferase [Cell envelope biogenesis, outer membrane]; Region: {ManC}; COG0836
1034807001352	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
1034807001353	Substrate binding site; other site
1034807001354	inorganic pyrophosphatase; Provisional; Region: PRK02230
1034807001355	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
1034807001356	dimer interface [polypeptide binding]; other site
1034807001357	substrate binding site [chemical binding]; other site
1034807001358	metal binding sites [ion binding]; metal-binding site
1034807001359	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1034807001360	endonuclease III; Region: ENDO3c; smart00478
1034807001361	minor groove reading motif; other site
1034807001362	helix-hairpin-helix signature motif; other site
1034807001363	substrate binding pocket [chemical binding]; other site
1034807001364	active site
1034807001365	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1034807001366	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
1034807001367	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
1034807001368	alpha subunit interface [polypeptide binding]; other site
1034807001369	TPP binding site [chemical binding]; other site
1034807001370	heterodimer interface [polypeptide binding]; other site
1034807001371	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1034807001372	RNA-binding proteins (RRM domain) [General function prediction only]; Region: COG0724
1034807001373	RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins; Region: RRM_HP0827_like; cd12399
1034807001374	SnoaL-like domain; Region: SnoaL_3; pfam13474
1034807001375	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1034807001376	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1034807001377	catalytic residues [active]
1034807001378	NADP+-dependent non-phosphorylating glyceraldehyde 3-phosphate dehydrogenase and ALDH family 11; Region: ALDH_F11_NP-GAPDH; cd07082
1034807001379	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1034807001380	tetrameric interface [polypeptide binding]; other site
1034807001381	activator binding site; other site
1034807001382	NADP binding site [chemical binding]; other site
1034807001383	substrate binding site [chemical binding]; other site
1034807001384	catalytic residues [active]
1034807001385	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1034807001386	active site residue [active]
1034807001387	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1034807001388	MarR family; Region: MarR; pfam01047
1034807001389	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
1034807001390	dimer interface [polypeptide binding]; other site
1034807001391	FMN binding site [chemical binding]; other site
1034807001392	YceI-like domain; Region: YceI; pfam04264
1034807001393	Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626
1034807001394	Trehalase; Region: Trehalase; cl17346
1034807001395	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1034807001396	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034807001397	putative substrate translocation pore; other site
1034807001398	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1034807001399	dimer interface [polypeptide binding]; other site
1034807001400	putative radical transfer pathway; other site
1034807001401	diiron center [ion binding]; other site
1034807001402	tyrosyl radical; other site
1034807001403	ATP cone domain; Region: ATP-cone; pfam03477
1034807001404	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cl00264
1034807001405	ribonucleoside--diphosphate reductase large subunit; Region: PLN02437
1034807001406	ATP cone domain; Region: ATP-cone; pfam03477
1034807001407	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1034807001408	active site
1034807001409	dimer interface [polypeptide binding]; other site
1034807001410	catalytic residues [active]
1034807001411	effector binding site; other site
1034807001412	R2 peptide binding site; other site
1034807001413	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807001414	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1034807001415	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034807001416	active site
1034807001417	phosphorylation site [posttranslational modification]
1034807001418	intermolecular recognition site; other site
1034807001419	dimerization interface [polypeptide binding]; other site
1034807001420	LytTr DNA-binding domain; Region: LytTR; pfam04397
1034807001421	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
1034807001422	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
1034807001423	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
1034807001424	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
1034807001425	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
1034807001426	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807001427	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1034807001428	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1034807001429	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034807001430	TPR motif; other site
1034807001431	binding surface
1034807001432	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1034807001433	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1034807001434	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034807001435	binding surface
1034807001436	TPR motif; other site
1034807001437	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1034807001438	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
1034807001439	Histidine kinase; Region: His_kinase; pfam06580
1034807001440	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034807001441	ATP binding site [chemical binding]; other site
1034807001442	Mg2+ binding site [ion binding]; other site
1034807001443	G-X-G motif; other site
1034807001444	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
1034807001445	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
1034807001446	Walker A/P-loop; other site
1034807001447	ATP binding site [chemical binding]; other site
1034807001448	Q-loop/lid; other site
1034807001449	ABC transporter signature motif; other site
1034807001450	Walker B; other site
1034807001451	D-loop; other site
1034807001452	H-loop/switch region; other site
1034807001453	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
1034807001454	Permease; Region: Permease; pfam02405
1034807001455	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1034807001456	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1034807001457	active site
1034807001458	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
1034807001459	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034807001460	putative substrate translocation pore; other site
1034807001461	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034807001462	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1034807001463	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1034807001464	HlyD family secretion protein; Region: HlyD_3; pfam13437
1034807001465	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1034807001466	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1034807001467	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1034807001468	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1034807001469	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1034807001470	dimer interface [polypeptide binding]; other site
1034807001471	anticodon binding site; other site
1034807001472	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1034807001473	homodimer interface [polypeptide binding]; other site
1034807001474	motif 1; other site
1034807001475	active site
1034807001476	motif 2; other site
1034807001477	GAD domain; Region: GAD; pfam02938
1034807001478	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1034807001479	motif 3; other site
1034807001480	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
1034807001481	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1034807001482	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
1034807001483	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
1034807001484	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1034807001485	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
1034807001486	NADH:ubiquinone oxidoreductase subunit 6 (chain J) [Energy production and conversion]; Region: NuoJ; COG0839
1034807001487	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
1034807001488	NADH-quinone oxidoreductase, chain I; Region: NuoI; TIGR01971
1034807001489	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1034807001490	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
1034807001491	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
1034807001492	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1034807001493	catalytic loop [active]
1034807001494	iron binding site [ion binding]; other site
1034807001495	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1034807001496	NADH-quinone oxidoreductase, F subunit; Region: nuoF_fam; TIGR01959
1034807001497	SLBB domain; Region: SLBB; pfam10531
1034807001498	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; smart00928
1034807001499	AAA domain; Region: AAA_21; pfam13304
1034807001500	Respiratory-chain NADH dehydrogenase 24 Kd subunit; Region: Complex1_24kDa; pfam01257
1034807001501	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
1034807001502	putative dimer interface [polypeptide binding]; other site
1034807001503	[2Fe-2S] cluster binding site [ion binding]; other site
1034807001504	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
1034807001505	NADH dehydrogenase subunit D; Validated; Region: PRK06075
1034807001506	Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Region: Complex1_30kDa; pfam00329
1034807001507	NADH dehydrogenase subunit B; Provisional; Region: PRK14820
1034807001508	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
1034807001509	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1034807001510	DNA-binding site [nucleotide binding]; DNA binding site
1034807001511	RNA-binding motif; other site
1034807001512	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1034807001513	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1034807001514	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1034807001515	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1034807001516	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1034807001517	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1034807001518	Sterol desaturase [Lipid metabolism]; Region: ERG3; COG3000
1034807001519	Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; pfam04116
1034807001520	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
1034807001521	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1034807001522	Uncharacterized conserved protein [Function unknown]; Region: COG3743
1034807001523	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1034807001524	aspartate aminotransferase; Provisional; Region: PRK05764
1034807001525	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1034807001526	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034807001527	homodimer interface [polypeptide binding]; other site
1034807001528	catalytic residue [active]
1034807001529	Fatty acid desaturase; Region: FA_desaturase; pfam00487
1034807001530	The Delta6 Fatty Acid Desaturase (Delta6-FADS)-like CD includes the integral-membrane enzymes: delta-4, delta-5, delta-6, delta-8, delta-8-sphingolipid, and delta-11 desaturases found in vertebrates, higher plants, fungi, and bacteria. These desaturases...; Region: Delta6-FADS-like; cd03506
1034807001531	putative di-iron ligands [ion binding]; other site
1034807001532	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
1034807001533	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034807001534	S-adenosylmethionine binding site [chemical binding]; other site
1034807001535	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1034807001536	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1034807001537	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1034807001538	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1034807001539	metal-binding site [ion binding]
1034807001540	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1034807001541	hopanoid-associated sugar epimerase; Region: HpnA; TIGR03466
1034807001542	NAD(P) binding site [chemical binding]; other site
1034807001543	active site
1034807001544	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1034807001545	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1034807001546	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1034807001547	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1034807001548	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1034807001549	Inhibitor of apoptosis-promoting Bax1; Region: Bax1-I; pfam01027
1034807001550	EamA-like transporter family; Region: EamA; pfam00892
1034807001551	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1034807001552	EamA-like transporter family; Region: EamA; pfam00892
1034807001553	kynureninase; Region: kynureninase; TIGR01814
1034807001554	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1034807001555	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1034807001556	catalytic residue [active]
1034807001557	3-hydroxybutyryl-CoA dehydratase; Validated; Region: PRK05809
1034807001558	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1034807001559	substrate binding site [chemical binding]; other site
1034807001560	oxyanion hole (OAH) forming residues; other site
1034807001561	trimer interface [polypeptide binding]; other site
1034807001562	bacillithiol system oxidoreductase, YphP/YqiW family; Region: YphP_YqiW; TIGR04191
1034807001563	methylated-DNA--protein-cysteine methyltransferase; Provisional; Region: PRK00901
1034807001564	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1034807001565	DNA binding site [nucleotide binding]
1034807001566	active site
1034807001567	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
1034807001568	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1034807001569	HAMP domain; Region: HAMP; pfam00672
1034807001570	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034807001571	dimer interface [polypeptide binding]; other site
1034807001572	phosphorylation site [posttranslational modification]
1034807001573	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034807001574	ATP binding site [chemical binding]; other site
1034807001575	Mg2+ binding site [ion binding]; other site
1034807001576	G-X-G motif; other site
1034807001577	Uncharacterized protein family (UPF0093); Region: UPF0093; pfam03653
1034807001578	Protein of unknown function (DUF1343); Region: DUF1343; pfam07075
1034807001579	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1034807001580	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
1034807001581	FtsX-like permease family; Region: FtsX; pfam02687
1034807001582	Electron transfer DM13; Region: DM13; pfam10517
1034807001583	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807001584	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
1034807001585	S23 ribosomal protein; Region: Ribosomal_S23p; pfam05635
1034807001586	four helix bundle protein; Region: TIGR02436
1034807001587	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
1034807001588	putative ABC transporter; Region: ycf24; CHL00085
1034807001589	Plasmid encoded toxin Txe; Region: Plasmid_Txe; cl17389
1034807001590	FeS assembly ATPase SufC; Region: sufC; TIGR01978
1034807001591	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
1034807001592	Walker A/P-loop; other site
1034807001593	ATP binding site [chemical binding]; other site
1034807001594	Q-loop/lid; other site
1034807001595	ABC transporter signature motif; other site
1034807001596	Walker B; other site
1034807001597	D-loop; other site
1034807001598	H-loop/switch region; other site
1034807001599	S23 ribosomal protein; Region: Ribosomal_S23p; pfam05635
1034807001600	four helix bundle protein; Region: TIGR02436
1034807001601	FeS assembly protein SufD; Region: sufD; TIGR01981
1034807001602	Uncharacterized protein family (UPF0051); Region: UPF0051; pfam01458
1034807001603	Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002
1034807001604	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
1034807001605	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
1034807001606	Domain of unknown function (DUF4296); Region: DUF4296; pfam14129
1034807001607	dihydroorotase; Reviewed; Region: PRK09236
1034807001608	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1034807001609	Dihydroorotase (DHOase), subgroup IIb; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This group contains the archeal members of the DHOase family; Region: DHOase_IIb; cd01318
1034807001610	active site
1034807001611	DPM1_like represents putative enzymes similar to eukaryotic DPM1; Region: DPM1_like; cd06442
1034807001612	Ligand binding site; other site
1034807001613	Putative Catalytic site; other site
1034807001614	DXD motif; other site
1034807001615	Domain of unknown function (DUF4271); Region: DUF4271; pfam14093
1034807001616	Uroporphyrinogen-III synthase [Coenzyme metabolism]; Region: HemD; COG1587
1034807001617	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1034807001618	active site
1034807001619	AAA domain; Region: AAA_23; pfam13476
1034807001620	AAA domain; Region: AAA_21; pfam13304
1034807001621	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1034807001622	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034807001623	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
1034807001624	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1034807001625	ATP binding site [chemical binding]; other site
1034807001626	putative Mg++ binding site [ion binding]; other site
1034807001627	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1034807001628	nucleotide binding region [chemical binding]; other site
1034807001629	ATP-binding site [chemical binding]; other site
1034807001630	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
1034807001631	amino acid transporter; Region: 2A0306; TIGR00909
1034807001632	DOMON-like type 9 carbohydrate binding module; Region: CBM9_like_2; cd09618
1034807001633	putative ligand binding site [chemical binding]; other site
1034807001634	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
1034807001635	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
1034807001636	Transposase; Region: DDE_Tnp_ISL3; pfam01610
1034807001637	N-terminal Early set domain associated with the catalytic domain of cellulase; Region: E_set_Cellulase_N; cd02850
1034807001638	Glycosyl hydrolase family 9; Region: Glyco_hydro_9; cl02959
1034807001639	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807001640	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1034807001641	Beta-lactamase; Region: Beta-lactamase; pfam00144
1034807001642	LGFP repeat; Region: LGFP; pfam08310
1034807001643	LGFP repeat; Region: LGFP; pfam08310
1034807001644	LGFP repeat; Region: LGFP; pfam08310
1034807001645	Phage Tail Collar Domain; Region: Collar; pfam07484
1034807001646	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807001647	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1034807001648	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034807001649	active site
1034807001650	phosphorylation site [posttranslational modification]
1034807001651	intermolecular recognition site; other site
1034807001652	dimerization interface [polypeptide binding]; other site
1034807001653	LytTr DNA-binding domain; Region: LytTR; smart00850
1034807001654	Histidine kinase; Region: His_kinase; pfam06580
1034807001655	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
1034807001656	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1034807001657	active site
1034807001658	catalytic site [active]
1034807001659	substrate binding site [chemical binding]; other site
1034807001660	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
1034807001661	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
1034807001662	active site
1034807001663	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1034807001664	generic binding surface II; other site
1034807001665	generic binding surface I; other site
1034807001666	PGAP1-like protein; Region: PGAP1; pfam07819
1034807001667	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1034807001668	cell division protein MraZ; Reviewed; Region: PRK00326
1034807001669	MraZ protein; Region: MraZ; pfam02381
1034807001670	MraZ protein; Region: MraZ; pfam02381
1034807001671	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1034807001672	MraW methylase family; Region: Methyltransf_5; cl17771
1034807001673	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
1034807001674	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1034807001675	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1034807001676	PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575
1034807001677	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1034807001678	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1034807001679	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1034807001680	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1034807001681	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1034807001682	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1034807001683	Mg++ binding site [ion binding]; other site
1034807001684	putative catalytic motif [active]
1034807001685	putative substrate binding site [chemical binding]; other site
1034807001686	UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell envelope biogenesis, outer membrane]; Region: MurD; COG0771
1034807001687	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1034807001688	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1034807001689	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
1034807001690	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1034807001691	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1034807001692	active site
1034807001693	homodimer interface [polypeptide binding]; other site
1034807001694	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1034807001695	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1034807001696	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1034807001697	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1034807001698	cell division protein FtsA; Region: ftsA; TIGR01174
1034807001699	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1034807001700	nucleotide binding site [chemical binding]; other site
1034807001701	SHS2 domain inserted in FTSA; Region: SHS2_FTSA; pfam02491
1034807001702	Cell division protein FtsA; Region: FtsA; pfam14450
1034807001703	cell division protein FtsZ; Validated; Region: PRK09330
1034807001704	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1034807001705	nucleotide binding site [chemical binding]; other site
1034807001706	SulA interaction site; other site
1034807001707	Yqey-like protein; Region: YqeY; pfam09424
1034807001708	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1034807001709	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1034807001710	substrate binding site [chemical binding]; other site
1034807001711	hexamer interface [polypeptide binding]; other site
1034807001712	metal binding site [ion binding]; metal-binding site
1034807001713	SWIM zinc finger; Region: SWIM; pfam04434
1034807001714	Bacterial SNF2 helicase associated; Region: SNF2_assoc; pfam08455
1034807001715	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
1034807001716	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1034807001717	ATP binding site [chemical binding]; other site
1034807001718	putative Mg++ binding site [ion binding]; other site
1034807001719	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1034807001720	nucleotide binding region [chemical binding]; other site
1034807001721	ATP-binding site [chemical binding]; other site
1034807001722	Outer membrane efflux protein; Region: OEP; pfam02321
1034807001723	Outer membrane efflux protein; Region: OEP; pfam02321
1034807001724	HlyD family secretion protein; Region: HlyD; pfam00529
1034807001725	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1034807001726	HlyD family secretion protein; Region: HlyD_3; pfam13437
1034807001727	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1034807001728	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034807001729	Walker A/P-loop; other site
1034807001730	ATP binding site [chemical binding]; other site
1034807001731	Q-loop/lid; other site
1034807001732	ABC transporter signature motif; other site
1034807001733	Walker B; other site
1034807001734	D-loop; other site
1034807001735	H-loop/switch region; other site
1034807001736	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1034807001737	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1034807001738	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1034807001739	Leucine-rich repeat (LRR) protein [Function unknown]; Region: COG4886
1034807001740	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4337
1034807001741	Amidinotransferase; Region: Amidinotransf; cl12043
1034807001742	Uncharacterized protein conserved in bacteria containing a pentein-type domain [Function unknown]; Region: COG4874
1034807001743	Amidinotransferase; Region: Amidinotransf; pfam02274
1034807001744	CoA binding domain; Region: CoA_binding_2; pfam13380
1034807001745	recombination protein RecR; Reviewed; Region: recR; PRK00076
1034807001746	RecR protein; Region: RecR; pfam02132
1034807001747	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1034807001748	putative active site [active]
1034807001749	putative metal-binding site [ion binding]; other site
1034807001750	tetramer interface [polypeptide binding]; other site
1034807001751	Periplasmic protein involved in polysaccharide export, contains    SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis]; Region: Wza; COG1596
1034807001752	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1034807001753	Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane]; Region: GumC; COG3206
1034807001754	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
1034807001755	probable UDP-glucose 6-dehydrogenase; Region: PLN02353
1034807001756	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1034807001757	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; Region: UDPG_MGDP_dh_C; pfam03720
1034807001758	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
1034807001759	Fibrobacter succinogenes paralogous family TIGR02171; Region: Fb_sc_TIGR02171
1034807001760	Vi polysaccharide biosynthesis protein TviB; Provisional; Region: PRK15182
1034807001761	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1034807001762	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1034807001763	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; Region: UDPG_MGDP_dh_C; pfam03720
1034807001764	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
1034807001765	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
1034807001766	NAD binding site [chemical binding]; other site
1034807001767	substrate binding site [chemical binding]; other site
1034807001768	homodimer interface [polypeptide binding]; other site
1034807001769	active site
1034807001770	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1034807001771	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034807001772	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
1034807001773	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1034807001774	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
1034807001775	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
1034807001776	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
1034807001777	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
1034807001778	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
1034807001779	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
1034807001780	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
1034807001781	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
1034807001782	Walker A/P-loop; other site
1034807001783	ATP binding site [chemical binding]; other site
1034807001784	Q-loop/lid; other site
1034807001785	ABC transporter signature motif; other site
1034807001786	Walker B; other site
1034807001787	D-loop; other site
1034807001788	H-loop/switch region; other site
1034807001789	C-Terminal domain of O-antigenic polysaccharide transporter protein Wzt and related proteins; Region: Wzt_C-like; cd10147
1034807001790	putative carbohydrate binding site [chemical binding]; other site
1034807001791	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
1034807001792	G1P_cytidylyltransferase catalyzes the production of CDP-D-Glucose; Region: G1P_cytidylyltransferase; cd02524
1034807001793	substrate binding site; other site
1034807001794	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1034807001795	CDP-glucose 4,6-dehydratase; Region: CDP_4_6_dhtase; TIGR02622
1034807001796	NAD(P) binding site [chemical binding]; other site
1034807001797	active site
1034807001798	lipopolysaccharide biosynthesis protein RfbH; Provisional; Region: PRK15407
1034807001799	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1034807001800	inhibitor-cofactor binding pocket; inhibition site
1034807001801	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034807001802	catalytic residue [active]
1034807001803	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1034807001804	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
1034807001805	NAD(P) binding site [chemical binding]; other site
1034807001806	active site
1034807001807	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1034807001808	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1034807001809	active site
1034807001810	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
1034807001811	trimer interface [polypeptide binding]; other site
1034807001812	active site
1034807001813	substrate binding site [chemical binding]; other site
1034807001814	CoA binding site [chemical binding]; other site
1034807001815	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1034807001816	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1034807001817	active site
1034807001818	methylmalonyl-CoA mutase; Reviewed; Region: PRK09426
1034807001819	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, Alpha subunit-like subfamily; contains proteins similar to the alpha subunit of Propionbacterium shermanni MCM, as well as human and E. coli MCM. Members of this subfamily contain...; Region: MM_CoA_mutase_alpha_like; cd03679
1034807001820	active site
1034807001821	substrate binding site [chemical binding]; other site
1034807001822	coenzyme B12 binding site [chemical binding]; other site
1034807001823	methylmalonyl CoA mutase B12 binding domain. This domain binds to B12 (adenosylcobamide), which initiates the conversion of succinyl CoA and methylmalonyl CoA by forming an adenosyl radical, which then undergoes a rearrangement exchanging a hydrogen atom...; Region: MM_CoA_mut_B12_BD; cd02071
1034807001824	B12 binding site [chemical binding]; other site
1034807001825	cobalt ligand [ion binding]; other site
1034807001826	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, Beta subunit-like subfamily; contains bacterial proteins similar to the beta subunit of MCMs from Propionbacterium shermanni and Streptomyces cinnamonensis, which are alpha/beta...; Region: MM_CoA_mutase_beta; cd03677
1034807001827	heterodimer interface [polypeptide binding]; other site
1034807001828	substrate interaction site [chemical binding]; other site
1034807001829	Septum formation initiator; Region: DivIC; cl17659
1034807001830	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
1034807001831	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
1034807001832	ATP-binding site [chemical binding]; other site
1034807001833	Sugar specificity; other site
1034807001834	Pyrimidine base specificity; other site
1034807001835	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1034807001836	active site
1034807001837	Methyltransferase domain; Region: Methyltransf_24; pfam13578
1034807001838	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1034807001839	active site
1034807001840	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1034807001841	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1034807001842	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1034807001843	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1034807001844	inhibitor-cofactor binding pocket; inhibition site
1034807001845	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034807001846	catalytic residue [active]
1034807001847	WbqC-like protein family; Region: WbqC; pfam08889
1034807001848	Putative Acyltransferase (AT), Left-handed parallel beta-Helix (LbH) domain; This group is composed of mostly uncharacterized proteins containing an N-terminal helical subdomain followed by a LbH domain. The alignment contains 6 turns, each containing...; Region: LbH_AT_putative; cd03360
1034807001849	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; Region: NeuD_NnaD; TIGR03570
1034807001850	putative trimer interface [polypeptide binding]; other site
1034807001851	putative CoA binding site [chemical binding]; other site
1034807001852	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1034807001853	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1034807001854	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1034807001855	active site
1034807001856	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1034807001857	Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands; Region: CE4_NodB_like_5s_6s; cd10918
1034807001858	putative active site [active]
1034807001859	putative metal binding site [ion binding]; other site
1034807001860	Formyltransferase, catalytic core domain; Region: FMT_core; cl00395
1034807001861	substrate binding site [chemical binding]; other site
1034807001862	active site
1034807001863	cosubstrate binding site; other site
1034807001864	catalytic site [active]
1034807001865	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1034807001866	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1034807001867	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1034807001868	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1034807001869	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1034807001870	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
1034807001871	Uncharacterized conserved protein [Function unknown]; Region: COG4278
1034807001872	Single strand annealing-weakened 1; Region: Saw1; pfam11561
1034807001873	RDD family; Region: RDD; pfam06271
1034807001874	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
1034807001875	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1034807001876	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1034807001877	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1034807001878	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
1034807001879	active site
1034807001880	DNA binding site [nucleotide binding]
1034807001881	Int/Topo IB signature motif; other site
1034807001882	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1034807001883	30S subunit binding site; other site
1034807001884	elongation factor Tu; Reviewed; Region: PRK12735
1034807001885	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1034807001886	G1 box; other site
1034807001887	GEF interaction site [polypeptide binding]; other site
1034807001888	GTP/Mg2+ binding site [chemical binding]; other site
1034807001889	Switch I region; other site
1034807001890	G2 box; other site
1034807001891	G3 box; other site
1034807001892	Switch II region; other site
1034807001893	G4 box; other site
1034807001894	G5 box; other site
1034807001895	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1034807001896	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1034807001897	Antibiotic Binding Site [chemical binding]; other site
1034807001898	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; pfam00584
1034807001899	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1034807001900	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1034807001901	putative homodimer interface [polypeptide binding]; other site
1034807001902	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1034807001903	heterodimer interface [polypeptide binding]; other site
1034807001904	homodimer interface [polypeptide binding]; other site
1034807001905	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1034807001906	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1034807001907	23S rRNA interface [nucleotide binding]; other site
1034807001908	L7/L12 interface [polypeptide binding]; other site
1034807001909	putative thiostrepton binding site; other site
1034807001910	L25 interface [polypeptide binding]; other site
1034807001911	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1034807001912	mRNA/rRNA interface [nucleotide binding]; other site
1034807001913	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1034807001914	23S rRNA interface [nucleotide binding]; other site
1034807001915	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1034807001916	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1034807001917	core dimer interface [polypeptide binding]; other site
1034807001918	peripheral dimer interface [polypeptide binding]; other site
1034807001919	L10 interface [polypeptide binding]; other site
1034807001920	L11 interface [polypeptide binding]; other site
1034807001921	putative EF-Tu interaction site [polypeptide binding]; other site
1034807001922	putative EF-G interaction site [polypeptide binding]; other site
1034807001923	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1034807001924	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1034807001925	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1034807001926	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1034807001927	RPB11 interaction site [polypeptide binding]; other site
1034807001928	RPB12 interaction site [polypeptide binding]; other site
1034807001929	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1034807001930	RPB3 interaction site [polypeptide binding]; other site
1034807001931	RPB1 interaction site [polypeptide binding]; other site
1034807001932	RPB11 interaction site [polypeptide binding]; other site
1034807001933	RPB10 interaction site [polypeptide binding]; other site
1034807001934	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1034807001935	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
1034807001936	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1034807001937	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1034807001938	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1034807001939	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
1034807001940	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1034807001941	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
1034807001942	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1034807001943	DNA binding site [nucleotide binding]
1034807001944	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1034807001945	Protein of unknown function (DUF3467); Region: DUF3467; pfam11950
1034807001946	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1034807001947	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
1034807001948	GDP-binding site [chemical binding]; other site
1034807001949	ACT binding site; other site
1034807001950	IMP binding site; other site
1034807001951	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1034807001952	metal binding site 2 [ion binding]; metal-binding site
1034807001953	putative DNA binding helix; other site
1034807001954	metal binding site 1 [ion binding]; metal-binding site
1034807001955	dimer interface [polypeptide binding]; other site
1034807001956	structural Zn2+ binding site [ion binding]; other site
1034807001957	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807001958	MoxR-like ATPases [General function prediction only]; Region: COG0714
1034807001959	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034807001960	Walker A motif; other site
1034807001961	ATP binding site [chemical binding]; other site
1034807001962	Walker B motif; other site
1034807001963	arginine finger; other site
1034807001964	SurA N-terminal domain; Region: SurA_N; pfam09312
1034807001965	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1034807001966	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1034807001967	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1034807001968	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1034807001969	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
1034807001970	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
1034807001971	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
1034807001972	G1 box; other site
1034807001973	putative GEF interaction site [polypeptide binding]; other site
1034807001974	GTP/Mg2+ binding site [chemical binding]; other site
1034807001975	Switch I region; other site
1034807001976	G2 box; other site
1034807001977	G3 box; other site
1034807001978	Switch II region; other site
1034807001979	G4 box; other site
1034807001980	G5 box; other site
1034807001981	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
1034807001982	glyceraldehyde-3-phosphate dehydrogenase; Reviewed; Region: PRK08289
1034807001983	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
1034807001984	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1034807001985	Uncharacterized subfamily of the tetrapyrrole methylase family similar to ribosomal RNA small subunit methyltransferase I (RsmI); Region: RsmI_like; cd11649
1034807001986	putative SAM binding site [chemical binding]; other site
1034807001987	homodimer interface [polypeptide binding]; other site
1034807001988	methyltransferase, FkbM family; Region: fkbM_fam; TIGR01444
1034807001989	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1034807001990	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1034807001991	superfamily containing globins and truncated hemoglobins; Region: globin_like; cl00280
1034807001992	heme-binding site [chemical binding]; other site
1034807001993	3-oxoacyl-[acyl-carrier-protein]; Region: FabH; COG0332
1034807001994	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1034807001995	dimer interface [polypeptide binding]; other site
1034807001996	active site
1034807001997	CoA binding pocket [chemical binding]; other site
1034807001998	Smr domain; Region: Smr; cl02619
1034807001999	phosphoglucosamine mutase; Region: Arch_GlmM; TIGR03990
1034807002000	This PGM-like (phosphoglucomutase-like) domain is located C-terminal to a mannose-1-phosphate guanyltransferase domain in a protein of unknown function that is found in both prokaryotes and eukaryotes. This domain belongs to the alpha-D-phosphohexomutase...; Region: PGM_like4; cd05803
1034807002001	active site
1034807002002	substrate binding site [chemical binding]; other site
1034807002003	metal binding site [ion binding]; metal-binding site
1034807002004	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1034807002005	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1034807002006	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1034807002007	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1034807002008	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N_2; pfam13588
1034807002009	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
1034807002010	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1034807002011	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034807002012	non-specific DNA binding site [nucleotide binding]; other site
1034807002013	salt bridge; other site
1034807002014	sequence-specific DNA binding site [nucleotide binding]; other site
1034807002015	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism]; Region: COG4799
1034807002016	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1034807002017	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
1034807002018	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
1034807002019	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1034807002020	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1034807002021	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1034807002022	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1034807002023	carboxyltransferase (CT) interaction site; other site
1034807002024	biotinylation site [posttranslational modification]; other site
1034807002025	B12 binding domain; Region: B12-binding; pfam02310
1034807002026	B12 binding site [chemical binding]; other site
1034807002027	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
1034807002028	Protein of unknown function (DUF1572); Region: DUF1572; pfam07609
1034807002029	DinB superfamily; Region: DinB_2; pfam12867
1034807002030	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1034807002031	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1034807002032	tetramer interface [polypeptide binding]; other site
1034807002033	threonine dehydratase; Validated; Region: PRK08639
1034807002034	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034807002035	catalytic residue [active]
1034807002036	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1034807002037	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1034807002038	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
1034807002039	putative valine binding site [chemical binding]; other site
1034807002040	dimer interface [polypeptide binding]; other site
1034807002041	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
1034807002042	acetolactate synthase, large subunit, biosynthetic type; Region: acolac_lg; TIGR00118
1034807002043	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1034807002044	PYR/PP interface [polypeptide binding]; other site
1034807002045	dimer interface [polypeptide binding]; other site
1034807002046	TPP binding site [chemical binding]; other site
1034807002047	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1034807002048	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1034807002049	TPP-binding site [chemical binding]; other site
1034807002050	dimer interface [polypeptide binding]; other site
1034807002051	dihydroxy-acid dehydratase; Provisional; Region: PRK00911
1034807002052	Domain of unknown function (DUF4262); Region: DUF4262; pfam14081
1034807002053	Protein of unknown function (DUF1569); Region: DUF1569; pfam07606
1034807002054	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG3392
1034807002055	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
1034807002056	Domain of unknown function (DUF4259); Region: DUF4259; pfam14078
1034807002057	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4884
1034807002058	Predicted permeases [General function prediction only]; Region: RarD; COG2962
1034807002059	EamA-like transporter family; Region: EamA; pfam00892
1034807002060	EamA-like transporter family; Region: EamA; pfam00892
1034807002061	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1034807002062	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
1034807002063	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1034807002064	catalytic residue [active]
1034807002065	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1034807002066	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
1034807002067	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1034807002068	Carbamoylphosphate synthase large subunit (split gene in MJ) [Amino acid transport and metabolism / Nucleotide transport and metabolism]; Region: CarB; COG0458
1034807002069	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1034807002070	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
1034807002071	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; smart01096
1034807002072	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1034807002073	Carbamoylphosphate synthase large subunit (split gene in MJ) [Amino acid transport and metabolism / Nucleotide transport and metabolism]; Region: CarB; COG0458
1034807002074	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1034807002075	Uncharacterized FAD-dependent dehydrogenases [General function prediction only]; Region: COG2509
1034807002076	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1034807002077	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; cl14958
1034807002078	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1034807002079	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
1034807002080	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1034807002081	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1034807002082	Domain of unknown function (DUF1877); Region: DUF1877; pfam08974
1034807002083	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1034807002084	HlyD family secretion protein; Region: HlyD_3; pfam13437
1034807002085	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
1034807002086	Dodecin; Region: Dodecin; pfam07311
1034807002087	MgtC family; Region: MgtC; pfam02308
1034807002088	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
1034807002089	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1034807002090	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1034807002091	Copper chaperone [Inorganic ion transport and metabolism]; Region: CopZ; COG2608
1034807002092	metal-binding site [ion binding]
1034807002093	Protein of unknown function (DUF3347); Region: DUF3347; pfam11827
1034807002094	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1034807002095	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1034807002096	catalytic residues [active]
1034807002097	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1034807002098	metal-binding site [ion binding]
1034807002099	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1034807002100	metal-binding site [ion binding]
1034807002101	copper-resistance protein, CopA family; Region: copper_res_A; TIGR01480
1034807002102	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1034807002103	Multicopper oxidase; Region: Cu-oxidase; pfam00394
1034807002104	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1034807002105	Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: STE14; COG2020
1034807002106	Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: STE14; COG2020
1034807002107	PQQ-like domain; Region: PQQ_2; pfam13360
1034807002108	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
1034807002109	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
1034807002110	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
1034807002111	dimer interface [polypeptide binding]; other site
1034807002112	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1034807002113	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
1034807002114	hydrophobic ligand binding site; other site
1034807002115	asparagine synthetase B; Provisional; Region: asnB; PRK09431
1034807002116	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
1034807002117	active site
1034807002118	dimer interface [polypeptide binding]; other site
1034807002119	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
1034807002120	Ligand Binding Site [chemical binding]; other site
1034807002121	Molecular Tunnel; other site
1034807002122	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1034807002123	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1034807002124	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1034807002125	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1034807002126	AAA domain; Region: AAA_30; pfam13604
1034807002127	Family description; Region: UvrD_C_2; pfam13538
1034807002128	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
1034807002129	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807002130	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1034807002131	Glycosyl transferases group 1; Region: Glyco_trans_1_2; pfam13524
1034807002132	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1034807002133	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1034807002134	WxcM-like, C-terminal; Region: FdtA; pfam05523
1034807002135	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1034807002136	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1034807002137	active site
1034807002138	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1034807002139	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1034807002140	active site
1034807002141	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; pfam13640
1034807002142	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1034807002143	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1034807002144	ligand binding site [chemical binding]; other site
1034807002145	flexible hinge region; other site
1034807002146	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1034807002147	putative switch regulator; other site
1034807002148	non-specific DNA interactions [nucleotide binding]; other site
1034807002149	DNA binding site [nucleotide binding]
1034807002150	sequence specific DNA binding site [nucleotide binding]; other site
1034807002151	putative cAMP binding site [chemical binding]; other site
1034807002152	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
1034807002153	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1034807002154	Tetramer interface [polypeptide binding]; other site
1034807002155	active site
1034807002156	FMN-binding site [chemical binding]; other site
1034807002157	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
1034807002158	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1034807002159	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1034807002160	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
1034807002161	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034807002162	Walker A motif; other site
1034807002163	ATP binding site [chemical binding]; other site
1034807002164	Walker B motif; other site
1034807002165	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1034807002166	Clp protease; Region: CLP_protease; pfam00574
1034807002167	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1034807002168	oligomer interface [polypeptide binding]; other site
1034807002169	active site residues [active]
1034807002170	trigger factor; Region: tig; TIGR00115
1034807002171	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1034807002172	Protein of unknown function DUF58; Region: DUF58; pfam01882
1034807002173	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
1034807002174	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1034807002175	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
1034807002176	putative NAD(P) binding site [chemical binding]; other site
1034807002177	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
1034807002178	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1034807002179	RuvA N terminal domain; Region: RuvA_N; pfam01330
1034807002180	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1034807002181	cell surface protein SprA; Region: surface_SprA; TIGR04189
1034807002182	Motility related/secretion protein; Region: SprA_N; pfam14349
1034807002183	Motility related/secretion protein; Region: SprA_N; pfam14349
1034807002184	Motility related/secretion protein; Region: SprA_N; pfam14349
1034807002185	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315
1034807002186	DNA binding residues [nucleotide binding]
1034807002187	dimerization interface [polypeptide binding]; other site
1034807002188	Cytochrome c; Region: Cytochrom_C; pfam00034
1034807002189	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
1034807002190	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1034807002191	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1034807002192	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
1034807002193	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1034807002194	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1034807002195	Heat-labile enterotoxin alpha chain; Region: Enterotoxin_a; pfam01375
1034807002196	Family description; Region: VCBS; pfam13517
1034807002197	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807002198	Chlorophyll A-B binding protein; Region: Chloroa_b-bind; cl02879
1034807002199	Ornithine/acetylornithine aminotransferase [Amino acid transport and metabolism]; Region: ArgD; COG4992
1034807002200	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1034807002201	inhibitor-cofactor binding pocket; inhibition site
1034807002202	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034807002203	catalytic residue [active]
1034807002204	OstA-like protein; Region: OstA_2; pfam13100
1034807002205	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1034807002206	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1034807002207	catalytic triad [active]
1034807002208	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
1034807002209	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1034807002210	minor groove reading motif; other site
1034807002211	helix-hairpin-helix signature motif; other site
1034807002212	substrate binding pocket [chemical binding]; other site
1034807002213	active site
1034807002214	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1034807002215	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1034807002216	active site residue [active]
1034807002217	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1034807002218	active site residue [active]
1034807002219	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1034807002220	metal-binding site [ion binding]
1034807002221	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034807002222	S-adenosylmethionine binding site [chemical binding]; other site
1034807002223	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cl00207
1034807002224	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1034807002225	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1034807002226	catalytic residues [active]
1034807002227	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1034807002228	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1034807002229	catalytic residues [active]
1034807002230	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1034807002231	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
1034807002232	NAD(P) binding pocket [chemical binding]; other site
1034807002233	TonB family C-terminal domain; Region: tonB_Cterm; TIGR01352
1034807002234	PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_4; cd03395
1034807002235	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1034807002236	active site
1034807002237	Sec-independent protein secretion pathway components [Intracellular trafficking and secretion]; Region: TatA; COG1826
1034807002238	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
1034807002239	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
1034807002240	active site
1034807002241	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034807002242	TPR motif; other site
1034807002243	binding surface
1034807002244	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated; Region: PRK06080
1034807002245	UbiA prenyltransferase family; Region: UbiA; pfam01040
1034807002246	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1034807002247	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
1034807002248	substrate binding site [chemical binding]; other site
1034807002249	oxyanion hole (OAH) forming residues; other site
1034807002250	trimer interface [polypeptide binding]; other site
1034807002251	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1034807002252	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1034807002253	Predicted membrane protein [Function unknown]; Region: COG4485
1034807002254	Putative MetA-pathway of phenol degradation; Region: Phenol_MetA_deg; pfam13557
1034807002255	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034807002256	Coenzyme A binding pocket [chemical binding]; other site
1034807002257	Domain of unknown function (DUF4258); Region: DUF4258; pfam14076
1034807002258	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
1034807002259	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
1034807002260	hexamer interface [polypeptide binding]; other site
1034807002261	ligand binding site [chemical binding]; other site
1034807002262	putative active site [active]
1034807002263	NAD(P) binding site [chemical binding]; other site
1034807002264	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034807002265	Coenzyme A binding pocket [chemical binding]; other site
1034807002266	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
1034807002267	Response regulator receiver domain; Region: Response_reg; pfam00072
1034807002268	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034807002269	active site
1034807002270	phosphorylation site [posttranslational modification]
1034807002271	intermolecular recognition site; other site
1034807002272	dimerization interface [polypeptide binding]; other site
1034807002273	PglZ domain; Region: PglZ; pfam08665
1034807002274	imidazolonepropionase; Validated; Region: PRK09356
1034807002275	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
1034807002276	active site
1034807002277	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
1034807002278	Thermotoga maritima CorA_like subfamily; Region: TmCorA-like_1; cd12828
1034807002279	oligomer interface [polypeptide binding]; other site
1034807002280	metal binding site [ion binding]; metal-binding site
1034807002281	metal binding site [ion binding]; metal-binding site
1034807002282	Cl binding site [ion binding]; other site
1034807002283	aspartate ring; other site
1034807002284	basic sphincter; other site
1034807002285	putative hydrophobic gate; other site
1034807002286	periplasmic entrance; other site
1034807002287	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1034807002288	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1034807002289	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1034807002290	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
1034807002291	ArsC family; Region: ArsC; pfam03960
1034807002292	catalytic residues [active]
1034807002293	CAAX protease self-immunity; Region: Abi; pfam02517
1034807002294	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1034807002295	AMP binding site [chemical binding]; other site
1034807002296	active site
1034807002297	acyl-activating enzyme (AAE) consensus motif; other site
1034807002298	CoA binding site [chemical binding]; other site
1034807002299	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
1034807002300	AAA domain; Region: AAA_11; pfam13086
1034807002301	AAA domain; Region: AAA_30; pfam13604
1034807002302	PIN domain; Region: PIN_Smg5-Smg6-like; cd09880
1034807002303	putative active site [active]
1034807002304	Peptidase M1 family Aminopeptidase N; Region: M1_APN_4; cd09603
1034807002305	Zn binding site [ion binding]; other site
1034807002306	C-terminal processing peptidase family S41; Region: Peptidase_S41; cd06567
1034807002307	Active site serine [active]
1034807002308	Protein of unknown function (DUF2400); Region: DUF2400; pfam09674
1034807002309	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1034807002310	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1034807002311	Walker A/P-loop; other site
1034807002312	ATP binding site [chemical binding]; other site
1034807002313	Q-loop/lid; other site
1034807002314	ABC transporter signature motif; other site
1034807002315	Walker B; other site
1034807002316	D-loop; other site
1034807002317	H-loop/switch region; other site
1034807002318	Rrf2 family protein; Region: rrf2_super; TIGR00738
1034807002319	Transcriptional regulator; Region: Rrf2; pfam02082
1034807002320	O-succinylhomoserine sulfhydrylase; Validated; Region: PRK08133
1034807002321	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1034807002322	homodimer interface [polypeptide binding]; other site
1034807002323	substrate-cofactor binding pocket; other site
1034807002324	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034807002325	catalytic residue [active]
1034807002326	TPR repeat; Region: TPR_11; pfam13414
1034807002327	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034807002328	binding surface
1034807002329	TPR motif; other site
1034807002330	Predicted redox protein, regulator of disulfide bond formation [Posttranslational modification, protein turnover, chaperones]; Region: COG1765
1034807002331	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
1034807002332	chaperonin_like superfamily. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. There are 2 main chaperonin groups. The symmetry of type I...; Region: chaperonin_like; cl02777
1034807002333	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
1034807002334	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
1034807002335	nucleotide binding site [chemical binding]; other site
1034807002336	substrate binding site [chemical binding]; other site
1034807002337	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1034807002338	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1034807002339	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1034807002340	homoserine O-acetyltransferase; Region: homoserO_Ac_trn; TIGR01392
1034807002341	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
1034807002342	O-acetylhomoserine sulfhydrylase [Amino acid transport and metabolism]; Region: MET17; COG2873
1034807002343	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1034807002344	homodimer interface [polypeptide binding]; other site
1034807002345	substrate-cofactor binding pocket; other site
1034807002346	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034807002347	catalytic residue [active]
1034807002348	Pirin-related protein [General function prediction only]; Region: COG1741
1034807002349	Pirin; Region: Pirin; pfam02678
1034807002350	Protein related to penicillin acylase [General function prediction only]; Region: COG2366
1034807002351	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
1034807002352	Penicillin G acylase (PGA) belongs to a family of beta-lactam acylases that includes cephalosporin acylase (CA) and aculeacin A acylase. PGA and CA are crucial for the production of backbone chemicals like 6-aminopenicillanic acid and...; Region: Ntn_PGA_like; cd03747
1034807002353	active site
1034807002354	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
1034807002355	hypothetical protein; Provisional; Region: PRK06753
1034807002356	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1034807002357	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1034807002358	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1034807002359	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1034807002360	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1034807002361	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
1034807002362	RNase E interface [polypeptide binding]; other site
1034807002363	trimer interface [polypeptide binding]; other site
1034807002364	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1034807002365	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1034807002366	RNase E interface [polypeptide binding]; other site
1034807002367	trimer interface [polypeptide binding]; other site
1034807002368	active site
1034807002369	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1034807002370	putative nucleic acid binding region [nucleotide binding]; other site
1034807002371	G-X-X-G motif; other site
1034807002372	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1034807002373	RNA binding site [nucleotide binding]; other site
1034807002374	domain interface; other site
1034807002375	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1034807002376	16S/18S rRNA binding site [nucleotide binding]; other site
1034807002377	S13e-L30e interaction site [polypeptide binding]; other site
1034807002378	25S rRNA binding site [nucleotide binding]; other site
1034807002379	MiaE tRNA-modifying nonheme diiron monooxygenase, ferritin-like diiron-binding domain; Region: MiaE; cd07910
1034807002380	active site
1034807002381	dinuclear metal binding site [ion binding]; other site
1034807002382	dimerization interface [polypeptide binding]; other site
1034807002383	Glycosyl transferases group 1; Region: Glyco_trans_1_4; pfam13692
1034807002384	adenylate kinase; Reviewed; Region: adk; PRK00279
1034807002385	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1034807002386	AMP-binding site [chemical binding]; other site
1034807002387	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1034807002388	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1034807002389	Domain of unknown function DUF21; Region: DUF21; pfam01595
1034807002390	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1034807002391	Transporter associated domain; Region: CorC_HlyC; smart01091
1034807002392	GTPase CgtA; Reviewed; Region: obgE; PRK12299
1034807002393	GTP1/OBG; Region: GTP1_OBG; pfam01018
1034807002394	Obg GTPase; Region: Obg; cd01898
1034807002395	G1 box; other site
1034807002396	GTP/Mg2+ binding site [chemical binding]; other site
1034807002397	Switch I region; other site
1034807002398	G2 box; other site
1034807002399	G3 box; other site
1034807002400	Switch II region; other site
1034807002401	G4 box; other site
1034807002402	G5 box; other site
1034807002403	Membrane protein of unknown function; Region: DUF360; pfam04020
1034807002404	acyl-CoA esterase; Provisional; Region: PRK10673
1034807002405	PGAP1-like protein; Region: PGAP1; pfam07819
1034807002406	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
1034807002407	active site
1034807002408	hydrophilic channel; other site
1034807002409	dimerization interface [polypeptide binding]; other site
1034807002410	catalytic residues [active]
1034807002411	active site lid [active]
1034807002412	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
1034807002413	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK01911
1034807002414	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03708
1034807002415	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1034807002416	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
1034807002417	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
1034807002418	Leucine rich repeat; Region: LRR_8; pfam13855
1034807002419	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807002420	conserved hypothetical protein; Region: Lon_rel_chp; TIGR02653
1034807002421	Putative ATP-dependent Lon protease; Region: Lon_2; pfam13337
1034807002422	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1034807002423	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
1034807002424	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
1034807002425	MTH538 TIR-like domain (DUF1863); Region: DUF1863; pfam08937
1034807002426	TIR domain; Region: TIR_2; cl17458
1034807002427	type II restriction m6 adenine DNA methyltransferase, Alw26I/Eco31I/Esp3I family; Region: met_A_Alw26; TIGR02987
1034807002428	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
1034807002429	Putative inner membrane protein (DUF1819); Region: DUF1819; pfam08849
1034807002430	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
1034807002431	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1034807002432	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
1034807002433	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
1034807002434	Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only]; Region: COG2996
1034807002435	S1 domain; Region: S1_2; pfam13509
1034807002436	S1 domain; Region: S1_2; pfam13509
1034807002437	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1034807002438	RNA binding site [nucleotide binding]; other site
1034807002439	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
1034807002440	Catalytic LigB subunit of aromatic ring-opening dioxygenase; Region: LigB; pfam02900
1034807002441	putative active site [active]
1034807002442	metal binding site [ion binding]; metal-binding site
1034807002443	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
1034807002444	lipoyl attachment site [posttranslational modification]; other site
1034807002445	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
1034807002446	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
1034807002447	dimer interface [polypeptide binding]; other site
1034807002448	tetramer interface [polypeptide binding]; other site
1034807002449	PYR/PP interface [polypeptide binding]; other site
1034807002450	TPP binding site [chemical binding]; other site
1034807002451	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
1034807002452	TPP-binding site; other site
1034807002453	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1034807002454	putative trimer interface [polypeptide binding]; other site
1034807002455	WcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain: This group is composed of Xanthomonas campestris WcxM and proteins with similarity to the WcxM N-terminal domain. WcxM is thought to be bifunctional, catalyzing both the isomerization...; Region: LbH_WxcM_N_like; cd03358
1034807002456	putative CoA binding site [chemical binding]; other site
1034807002457	putative trimer interface [polypeptide binding]; other site
1034807002458	putative active site [active]
1034807002459	putative substrate binding site [chemical binding]; other site
1034807002460	putative CoA binding site [chemical binding]; other site
1034807002461	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1034807002462	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1034807002463	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1034807002464	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
1034807002465	UDP-N-acetylglucosamine 4,6-dehydratase/5-epimerase; Region: FnlA; TIGR04130
1034807002466	NAD(P) binding site [chemical binding]; other site
1034807002467	homodimer interface [polypeptide binding]; other site
1034807002468	substrate binding site [chemical binding]; other site
1034807002469	active site
1034807002470	Polysaccharide biosynthesis protein C-terminal; Region: Polysacc_syn_2C; pfam08485
1034807002471	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; cl17405
1034807002472	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1034807002473	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1034807002474	NAD(P) binding site [chemical binding]; other site
1034807002475	active site
1034807002476	dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfbC; COG1898
1034807002477	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
1034807002478	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1034807002479	active site
1034807002480	homodimer interface [polypeptide binding]; other site
1034807002481	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
1034807002482	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034807002483	S-adenosylmethionine binding site [chemical binding]; other site
1034807002484	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1034807002485	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1034807002486	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1034807002487	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1034807002488	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1034807002489	glycogen synthase, Corynebacterium family; Region: glgA_Coryne; TIGR02149
1034807002490	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1034807002491	Asparagine synthase (glutamine-hydrolyzing) [Amino acid transport and metabolism]; Region: AsnB; COG0367
1034807002492	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
1034807002493	active site
1034807002494	dimer interface [polypeptide binding]; other site
1034807002495	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
1034807002496	Ligand Binding Site [chemical binding]; other site
1034807002497	Molecular Tunnel; other site
1034807002498	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13181
1034807002499	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
1034807002500	putative active site [active]
1034807002501	oxyanion strand; other site
1034807002502	catalytic triad [active]
1034807002503	imidazole glycerol phosphate synthase subunit HisF; Provisional; Region: PRK01033
1034807002504	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
1034807002505	substrate binding site [chemical binding]; other site
1034807002506	glutamase interaction surface [polypeptide binding]; other site
1034807002507	Uncharacterized protein conserved in archaea [Function unknown]; Region: COG1817
1034807002508	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
1034807002509	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_III; cd01996
1034807002510	Ligand Binding Site [chemical binding]; other site
1034807002511	Bacterial sugar transferase; Region: Bac_transf; cl00939
1034807002512	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1034807002513	Periplasmic protein involved in polysaccharide export, contains    SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis]; Region: Wza; COG1596
1034807002514	SLBB domain; Region: SLBB; pfam10531
1034807002515	Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane]; Region: GumC; COG3206
1034807002516	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
1034807002517	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
1034807002518	Nucleotide binding site [chemical binding]; other site
1034807002519	P loop; other site
1034807002520	DTAP/Switch II; other site
1034807002521	Switch I; other site
1034807002522	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism]; Region: COG4799
1034807002523	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
1034807002524	hypothetical protein; Reviewed; Region: PRK09588
1034807002525	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1034807002526	peptide chain release factor-like protein; Reviewed; Region: prfH; PRK08179
1034807002527	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1034807002528	TPR motif; other site
1034807002529	binding surface
1034807002530	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
1034807002531	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1034807002532	putative DNA binding site [nucleotide binding]; other site
1034807002533	putative Zn2+ binding site [ion binding]; other site
1034807002534	AsnC family; Region: AsnC_trans_reg; pfam01037
1034807002535	Putative cyclase; Region: Cyclase; pfam04199
1034807002536	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
1034807002537	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
1034807002538	hypothetical protein; Provisional; Region: PRK06062
1034807002539	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1034807002540	inhibitor-cofactor binding pocket; inhibition site
1034807002541	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034807002542	catalytic residue [active]
1034807002543	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1034807002544	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034807002545	Coenzyme A binding pocket [chemical binding]; other site
1034807002546	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
1034807002547	active site clefts [active]
1034807002548	zinc binding site [ion binding]; other site
1034807002549	dimer interface [polypeptide binding]; other site
1034807002550	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
1034807002551	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
1034807002552	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1034807002553	Outer membrane protein family (DUF1597); Region: DUF1597; pfam07642
1034807002554	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
1034807002555	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
1034807002556	NAD(P) binding site [chemical binding]; other site
1034807002557	catalytic residues [active]
1034807002558	heat shock protein 90; Provisional; Region: PRK05218
1034807002559	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034807002560	ATP binding site [chemical binding]; other site
1034807002561	Mg2+ binding site [ion binding]; other site
1034807002562	G-X-G motif; other site
1034807002563	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
1034807002564	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1034807002565	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cd00449
1034807002566	homodimer interface [polypeptide binding]; other site
1034807002567	substrate-cofactor binding pocket; other site
1034807002568	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034807002569	catalytic residue [active]
1034807002570	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
1034807002571	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034807002572	ATP binding site [chemical binding]; other site
1034807002573	Mg2+ binding site [ion binding]; other site
1034807002574	G-X-G motif; other site
1034807002575	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
1034807002576	ATP binding site [chemical binding]; other site
1034807002577	MutL C terminal dimerisation domain; Region: MutL_C; smart00853
1034807002578	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
1034807002579	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
1034807002580	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1034807002581	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1034807002582	ligand binding site [chemical binding]; other site
1034807002583	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
1034807002584	putative switch regulator; other site
1034807002585	non-specific DNA interactions [nucleotide binding]; other site
1034807002586	DNA binding site [nucleotide binding]
1034807002587	sequence specific DNA binding site [nucleotide binding]; other site
1034807002588	putative cAMP binding site [chemical binding]; other site
1034807002589	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1034807002590	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1034807002591	P-loop; other site
1034807002592	Magnesium ion binding site [ion binding]; other site
1034807002593	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1034807002594	Magnesium ion binding site [ion binding]; other site
1034807002595	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
1034807002596	ParB-like nuclease domain; Region: ParBc; pfam02195
1034807002597	dihydrodipicolinate reductase; Provisional; Region: PRK00048
1034807002598	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1034807002599	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1034807002600	Signal peptidase I [Intracellular trafficking and secretion]; Region: LepB; COG0681
1034807002601	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1034807002602	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1034807002603	WbqC-like protein family; Region: WbqC; pfam08889
1034807002604	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; uncharacterized family 2; Region: EEP-2; cd09084
1034807002605	putative catalytic site [active]
1034807002606	putative metal binding site [ion binding]; other site
1034807002607	putative phosphate binding site [ion binding]; other site
1034807002608	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179
1034807002609	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
1034807002610	putative ATP binding site [chemical binding]; other site
1034807002611	putative substrate interface [chemical binding]; other site
1034807002612	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1034807002613	active site
1034807002614	Protein of unknown function (DUF1684); Region: DUF1684; pfam07920
1034807002615	Uncharacterized ACR, COG1678; Region: DUF179; pfam02622
1034807002616	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1034807002617	IHF - DNA interface [nucleotide binding]; other site
1034807002618	IHF dimer interface [polypeptide binding]; other site
1034807002619	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1034807002620	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1034807002621	putative active site [active]
1034807002622	substrate binding site [chemical binding]; other site
1034807002623	putative cosubstrate binding site; other site
1034807002624	catalytic site [active]
1034807002625	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1034807002626	substrate binding site [chemical binding]; other site
1034807002627	Superfamily II DNA helicase [DNA replication, recombination, and repair]; Region: RecQ; COG0514
1034807002628	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1034807002629	ATP binding site [chemical binding]; other site
1034807002630	putative Mg++ binding site [ion binding]; other site
1034807002631	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1034807002632	nucleotide binding region [chemical binding]; other site
1034807002633	ATP-binding site [chemical binding]; other site
1034807002634	Predicted ATPase [General function prediction only]; Region: COG3911
1034807002635	AAA domain; Region: AAA_28; pfam13521
1034807002636	Domain of Unknown Function (DUF1599); Region: DUF1599; pfam07659
1034807002637	Domain of Unknown Function (DUF1599); Region: DUF1599; pfam07659
1034807002638	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1034807002639	dihydropteroate synthase; Region: DHPS; TIGR01496
1034807002640	substrate binding pocket [chemical binding]; other site
1034807002641	dimer interface [polypeptide binding]; other site
1034807002642	inhibitor binding site; inhibition site
1034807002643	Protein of unknown function (DUF4199); Region: DUF4199; pfam13858
1034807002644	YCII-related domain; Region: YCII; cl00999
1034807002645	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
1034807002646	Scramblase; Region: Scramblase; pfam03803
1034807002647	Outer membrane cobalamin receptor protein [Coenzyme metabolism]; Region: BtuB; COG4206
1034807002648	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1034807002649	N-terminal plug; other site
1034807002650	ligand-binding site [chemical binding]; other site
1034807002651	Periplasmic binding protein TroA_d.  These proteins are predicted to function as initial receptors in the ABC metal ion uptake in eubacteria and archaea.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a...; Region: TroA_d; cd01141
1034807002652	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1034807002653	putative ligand binding site [chemical binding]; other site
1034807002654	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1034807002655	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1034807002656	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1034807002657	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
1034807002658	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034807002659	TPR motif; other site
1034807002660	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1034807002661	binding surface
1034807002662	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
1034807002663	Dehydroquinase class II; Region: DHquinase_II; pfam01220
1034807002664	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
1034807002665	trimer interface [polypeptide binding]; other site
1034807002666	active site
1034807002667	dimer interface [polypeptide binding]; other site
1034807002668	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1034807002669	hypothetical protein; Provisional; Region: PRK04233
1034807002670	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1034807002671	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1034807002672	Walker A/P-loop; other site
1034807002673	ATP binding site [chemical binding]; other site
1034807002674	Q-loop/lid; other site
1034807002675	ABC transporter signature motif; other site
1034807002676	Walker B; other site
1034807002677	D-loop; other site
1034807002678	H-loop/switch region; other site
1034807002679	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1034807002680	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1034807002681	ABC-ATPase subunit  interface; other site
1034807002682	dimer interface [polypeptide binding]; other site
1034807002683	putative PBP binding regions; other site
1034807002684	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1034807002685	active site
1034807002686	catalytic motif [active]
1034807002687	Zn binding site [ion binding]; other site
1034807002688	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
1034807002689	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1034807002690	FeS/SAM binding site; other site
1034807002691	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
1034807002692	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1034807002693	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1034807002694	Metallo-peptidase family M12B Reprolysin-like; Region: Reprolysin_2; pfam13574
1034807002695	Proprotein convertase P-domain; Region: P_proprotein; pfam01483
1034807002696	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807002697	metal-dependent hydrolase; Provisional; Region: PRK13291
1034807002698	DinB superfamily; Region: DinB_2; pfam12867
1034807002699	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1034807002700	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034807002701	S-adenosylmethionine binding site [chemical binding]; other site
1034807002702	Flagellin N-methylase; Region: FliB; pfam03692
1034807002703	gliding motility-associated ABC transporter ATP-binding subunit GldA; Region: GldA_ABC_ATP; TIGR03522
1034807002704	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1034807002705	Walker A/P-loop; other site
1034807002706	ATP binding site [chemical binding]; other site
1034807002707	Q-loop/lid; other site
1034807002708	ABC transporter signature motif; other site
1034807002709	Walker B; other site
1034807002710	D-loop; other site
1034807002711	H-loop/switch region; other site
1034807002712	excinuclease ABC subunit B; Provisional; Region: PRK05298
1034807002713	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1034807002714	ATP binding site [chemical binding]; other site
1034807002715	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1034807002716	nucleotide binding region [chemical binding]; other site
1034807002717	ATP-binding site [chemical binding]; other site
1034807002718	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1034807002719	UvrB/uvrC motif; Region: UVR; pfam02151
1034807002720	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1034807002721	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034807002722	Coenzyme A binding pocket [chemical binding]; other site
1034807002723	UDP-N-acetylmuramate-alanine ligase [Cell envelope biogenesis, outer membrane]; Region: MurC; COG0773
1034807002724	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1034807002725	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1034807002726	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1034807002727	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034807002728	binding surface
1034807002729	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1034807002730	TPR motif; other site
1034807002731	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1034807002732	binding surface
1034807002733	TPR motif; other site
1034807002734	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
1034807002735	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1034807002736	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1034807002737	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1034807002738	gliding motility-associated lipoprotein GldJ; Region: GldJ; TIGR03524
1034807002739	Peptidase C25 family N-terminal domain, found in Arg-gingipain (Rgp), Lys-gingipain (Kgp) and related proteins; Region: Peptidase_C25_N; cd02258
1034807002740	active site
1034807002741	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
1034807002742	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
1034807002743	Protein of unknown function DUF262; Region: DUF262; pfam03235
1034807002744	Uncharacterized conserved protein [Function unknown]; Region: COG1479
1034807002745	Protein of unknown function DUF262; Region: DUF262; pfam03235
1034807002746	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
1034807002747	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1034807002748	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1034807002749	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
1034807002750	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
1034807002751	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1034807002752	Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322
1034807002753	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1034807002754	active site residue [active]
1034807002755	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1034807002756	active site residue [active]
1034807002757	Domain of unknown function (DUF202); Region: DUF202; pfam02656
1034807002758	Zinc-dependent metalloprotease, pappalysin_like subfamily. The pregnancy-associated plasma protein A (PAPP-A or pappalysin-1) cleaves insulin-like growth factor-binding proteins 4 and 5, thereby promoting cell growth by releasing bound growth factor; Region: ZnMc_pappalysin_like; cd04275
1034807002759	active site
1034807002760	Protein of unknown function DUF2625; Region: DUF2625; pfam10946
1034807002761	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1034807002762	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1034807002763	ATP binding site [chemical binding]; other site
1034807002764	putative Mg++ binding site [ion binding]; other site
1034807002765	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1034807002766	nucleotide binding region [chemical binding]; other site
1034807002767	ATP-binding site [chemical binding]; other site
1034807002768	putative hydrolase; Provisional; Region: PRK02113
1034807002769	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
1034807002770	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1034807002771	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1034807002772	active site
1034807002773	HIGH motif; other site
1034807002774	nucleotide binding site [chemical binding]; other site
1034807002775	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1034807002776	active site
1034807002777	KMSKS motif; other site
1034807002778	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1034807002779	tRNA binding surface [nucleotide binding]; other site
1034807002780	anticodon binding site; other site
1034807002781	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1034807002782	legume lectins; Region: lectin_L-type; cd01951
1034807002783	homotetramer interaction site [polypeptide binding]; other site
1034807002784	carbohydrate binding site [chemical binding]; other site
1034807002785	metal binding site [ion binding]; metal-binding site
1034807002786	gliding motility-associated C-terminal domain; Region: Bac_Flav_CTERM; TIGR04131
1034807002787	Protein of unknown function (DUF1573); Region: DUF1573; pfam07610
1034807002788	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06416
1034807002789	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1034807002790	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1034807002791	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1034807002792	PrcB C-terminal; Region: PrcB_C; pfam14343
1034807002793	N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA; Region: thiol_BshA; TIGR03999
1034807002794	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_5; cd04962
1034807002795	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1034807002796	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1034807002797	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
1034807002798	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1034807002799	Beta-lactamase; Region: Beta-lactamase; cl17358
1034807002800	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1034807002801	Cysteine-rich domain; Region: CCG; pfam02754
1034807002802	Cysteine-rich domain; Region: CCG; pfam02754
1034807002803	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034807002804	active site
1034807002805	motif I; other site
1034807002806	motif II; other site
1034807002807	4Fe-4S dicluster domain; Region: Fer4_10; pfam13237
1034807002808	4Fe-4S binding domain; Region: Fer4; cl02805
1034807002809	4Fe-4S dicluster domain; Region: Fer4_8; pfam13183
1034807002810	virulence factor Mce family protein; Region: Mtu_fam_mce; TIGR00996
1034807002811	mce related protein; Region: MCE; pfam02470
1034807002812	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
1034807002813	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1034807002814	homotrimer interaction site [polypeptide binding]; other site
1034807002815	putative active site [active]
1034807002816	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1034807002817	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1034807002818	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1034807002819	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
1034807002820	Saccharopine Dehydrogenase like proteins; Region: SDH_like; cd05199
1034807002821	active site
1034807002822	ligand binding site [chemical binding]; other site
1034807002823	NAD(P) binding site [chemical binding]; other site
1034807002824	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1034807002825	Beta-lactamase; Region: Beta-lactamase; pfam00144
1034807002826	Peptidase M1 family containing bacterial Aminopeptidase N; Region: M1_APN_5; cd09604
1034807002827	Zn binding site [ion binding]; other site
1034807002828	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1034807002829	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1034807002830	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
1034807002831	active site pocket [active]
1034807002832	oxyanion hole [active]
1034807002833	catalytic triad [active]
1034807002834	active site nucleophile [active]
1034807002835	bacillithiol biosynthesis deacetylase BshB1; Region: thiol_BshB1; TIGR04001
1034807002836	chorismate binding enzyme; Region: Chorismate_bind; cl10555
1034807002837	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1034807002838	CoenzymeA binding site [chemical binding]; other site
1034807002839	subunit interaction site [polypeptide binding]; other site
1034807002840	PHB binding site; other site
1034807002841	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1034807002842	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1034807002843	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1034807002844	catalytic residue [active]
1034807002845	Formimidoylglutamase or HutE; Region: Formimidoylglutamase; cd09988
1034807002846	putative active site [active]
1034807002847	putative metal binding site [ion binding]; other site
1034807002848	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1034807002849	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1034807002850	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1034807002851	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
1034807002852	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
1034807002853	Transposase; Region: DDE_Tnp_ISL3; pfam01610
1034807002854	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1034807002855	TPR repeat; Region: TPR_11; pfam13414
1034807002856	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1034807002857	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1034807002858	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1034807002859	ligand binding site [chemical binding]; other site
1034807002860	Protein of unknown function (DUF3308); Region: DUF3308; pfam11751
1034807002861	CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; Region: CUB; cd00041
1034807002862	heterodimerization interface [polypeptide binding]; other site
1034807002863	CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast; Region: CUB; cd00041
1034807002864	heterodimerization interface [polypeptide binding]; other site
1034807002865	C-terminal domain of CHU protein family; Region: CHU_C; pfam13585
1034807002866	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
1034807002867	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
1034807002868	HflX GTPase family; Region: HflX; cd01878
1034807002869	G1 box; other site
1034807002870	GTP/Mg2+ binding site [chemical binding]; other site
1034807002871	Switch I region; other site
1034807002872	G2 box; other site
1034807002873	G3 box; other site
1034807002874	Switch II region; other site
1034807002875	G4 box; other site
1034807002876	G5 box; other site
1034807002877	twin arginine-targeting protein translocase, TatA/E family; Region: tatAE; TIGR01411
1034807002878	mttA/Hcf106 family; Region: MttA_Hcf106; pfam02416
1034807002879	GH3 auxin-responsive promoter; Region: GH3; pfam03321
1034807002880	Protein of unknown function (DUF4230); Region: DUF4230; pfam14014
1034807002881	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1034807002882	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1034807002883	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
1034807002884	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034807002885	Walker A/P-loop; other site
1034807002886	ATP binding site [chemical binding]; other site
1034807002887	Q-loop/lid; other site
1034807002888	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1034807002889	ABC transporter; Region: ABC_tran_2; pfam12848
1034807002890	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1034807002891	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1034807002892	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315
1034807002893	DNA binding residues [nucleotide binding]
1034807002894	Protein of unknown function (DUF2805); Region: DUF2805; pfam10985
1034807002895	Sterol desaturase [Lipid metabolism]; Region: ERG3; COG3000
1034807002896	Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; pfam04116
1034807002897	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1034807002898	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1034807002899	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1034807002900	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_2; pfam13532
1034807002901	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1034807002902	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1034807002903	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
1034807002904	Domain of unknown function (DUF4341); Region: DUF4341; pfam14241
1034807002905	Sulphur transport; Region: Sulf_transp; pfam04143
1034807002906	YhhN-like protein; Region: YhhN; pfam07947
1034807002907	Sterol desaturase [Lipid metabolism]; Region: ERG3; COG3000
1034807002908	Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; pfam04116
1034807002909	ATP-dependent Clp protease adaptor protein ClpS; Region: ClpS; pfam02617
1034807002910	ribosomal protein L11 methyltransferase; Reviewed; Region: prmA; PRK00517
1034807002911	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1034807002912	triosephosphate isomerase; Provisional; Region: PRK14567
1034807002913	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1034807002914	substrate binding site [chemical binding]; other site
1034807002915	dimer interface [polypeptide binding]; other site
1034807002916	catalytic triad [active]
1034807002917	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1034807002918	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1034807002919	catalytic residues [active]
1034807002920	Large-conductance mechanosensitive channel, MscL; Region: MscL; cl00860
1034807002921	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
1034807002922	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
1034807002923	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1034807002924	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
1034807002925	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
1034807002926	active site
1034807002927	S23 ribosomal protein; Region: Ribosomal_S23p; pfam05635
1034807002928	four helix bundle protein; Region: TIGR02436
1034807002929	acetyl-CoA acetyltransferase; Provisional; Region: PRK09052
1034807002930	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1034807002931	dimer interface [polypeptide binding]; other site
1034807002932	active site
1034807002933	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1034807002934	3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Region: FadB; COG1250
1034807002935	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1034807002936	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1034807002937	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1034807002938	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
1034807002939	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1034807002940	substrate binding site [chemical binding]; other site
1034807002941	oxyanion hole (OAH) forming residues; other site
1034807002942	trimer interface [polypeptide binding]; other site
1034807002943	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1034807002944	MarR family; Region: MarR; pfam01047
1034807002945	MarR family; Region: MarR_2; cl17246
1034807002946	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1034807002947	putative acyl-acceptor binding pocket; other site
1034807002948	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034807002949	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1034807002950	putative substrate translocation pore; other site
1034807002951	membrane ATPase/protein kinase; Provisional; Region: PRK09435
1034807002952	Circularly permuted YlqF-related GTPases; Region: YlqF_related_GTPase; cl17249
1034807002953	GTP/Mg2+ binding site [chemical binding]; other site
1034807002954	G5 box; other site
1034807002955	The function of this protein family is unkown. The protein sequences are similar to the ArgK protein in E. coli. ArgK protein is a membrane ATPase which is required for transporting arginine, ornithine and lysine into the cells by the arginine and...; Region: ArgK-like; cd03114
1034807002956	Walker A; other site
1034807002957	G1 box; other site
1034807002958	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
1034807002959	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
1034807002960	trimer interface [polypeptide binding]; other site
1034807002961	active site
1034807002962	substrate binding site [chemical binding]; other site
1034807002963	CoA binding site [chemical binding]; other site
1034807002964	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
1034807002965	Beta-eliminating lyase; Region: Beta_elim_lyase; pfam01212
1034807002966	tetramer interface [polypeptide binding]; other site
1034807002967	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034807002968	catalytic residue [active]
1034807002969	DNA polymerase III subunit beta; Validated; Region: PRK05643
1034807002970	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1034807002971	putative DNA binding surface [nucleotide binding]; other site
1034807002972	dimer interface [polypeptide binding]; other site
1034807002973	beta-clamp/clamp loader binding surface; other site
1034807002974	beta-clamp/translesion DNA polymerase binding surface; other site
1034807002975	gliding-associated putative ABC transporter substrate-binding component GldG; Region: GldG; TIGR03521
1034807002976	gliding motility-associated ABC transporter permease protein GldF; Region: ABC_perm_GldF; TIGR03518
1034807002977	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1034807002978	Protein of unknown function (DUF1569); Region: DUF1569; pfam07606
1034807002979	23S rRNA mA1618 methyltransferase; Provisional; Region: PRK11727
1034807002980	Protein of unknown function (DUF890); Region: Methyltransf_10; pfam05971
1034807002981	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1034807002982	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1034807002983	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1034807002984	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1034807002985	Protein of unknown function, DUF479; Region: DUF479; cl01203
1034807002986	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
1034807002987	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019
1034807002988	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1034807002989	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1034807002990	Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523
1034807002991	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034807002992	Coenzyme A binding pocket [chemical binding]; other site
1034807002993	Alkylmercury lyase; Region: MerB; pfam03243
1034807002994	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1034807002995	binding surface
1034807002996	TPR motif; other site
1034807002997	heat shock 70 kDa precursor protein; Provisional; Region: PTZ00186
1034807002998	Domain of unknown function (DUF3805); Region: DUF3805; pfam12712
1034807002999	Domain of unknown function (DUF4375); Region: DUF4375; pfam14300
1034807003000	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1034807003001	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034807003002	binding surface
1034807003003	TPR motif; other site
1034807003004	PQQ-like domain; Region: PQQ_2; pfam13360
1034807003005	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4884
1034807003006	Prolipoprotein diacylglyceryl transferase; Region: LGT; cl00478
1034807003007	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
1034807003008	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034807003009	Walker A/P-loop; other site
1034807003010	ATP binding site [chemical binding]; other site
1034807003011	Q-loop/lid; other site
1034807003012	ABC transporter signature motif; other site
1034807003013	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1034807003014	Walker B; other site
1034807003015	D-loop; other site
1034807003016	H-loop/switch region; other site
1034807003017	ABC transporter; Region: ABC_tran_2; pfam12848
1034807003018	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1034807003019	Methyltransferase domain; Region: Methyltransf_24; pfam13578
1034807003020	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1034807003021	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034807003022	Walker A/P-loop; other site
1034807003023	ATP binding site [chemical binding]; other site
1034807003024	Q-loop/lid; other site
1034807003025	ABC transporter signature motif; other site
1034807003026	Walker B; other site
1034807003027	D-loop; other site
1034807003028	H-loop/switch region; other site
1034807003029	ABC transporter; Region: ABC_tran_2; pfam12848
1034807003030	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1034807003031	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1034807003032	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
1034807003033	Probable Catalytic site; other site
1034807003034	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1034807003035	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
1034807003036	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1034807003037	E3 interaction surface; other site
1034807003038	lipoyl attachment site [posttranslational modification]; other site
1034807003039	e3 binding domain; Region: E3_binding; pfam02817
1034807003040	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1034807003041	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
1034807003042	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like; Region: ALDH_ACDHII-AcoD; cd07116
1034807003043	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1034807003044	NAD(P) binding site [chemical binding]; other site
1034807003045	catalytic residues [active]
1034807003046	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
1034807003047	Predicted periplasmic protein [Function unknown]; Region: COG3698
1034807003048	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
1034807003049	aspartate-semialdehyde dehydrogenase (peptidoglycan organisms); Region: asd_B; TIGR01296
1034807003050	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1034807003051	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1034807003052	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1034807003053	Protein of unknown function (DUF2805); Region: DUF2805; pfam10985
1034807003054	Protein of unknown function (DUF2452); Region: DUF2452; pfam10504
1034807003055	Flavin reductase like domain; Region: Flavin_Reduct; pfam01613
1034807003056	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1034807003057	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1034807003058	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1034807003059	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1034807003060	dimer interface [polypeptide binding]; other site
1034807003061	motif 1; other site
1034807003062	active site
1034807003063	motif 2; other site
1034807003064	motif 3; other site
1034807003065	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1034807003066	anticodon binding site; other site
1034807003067	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1034807003068	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1034807003069	FtsX-like permease family; Region: FtsX; pfam02687
1034807003070	GMP synthase; Reviewed; Region: guaA; PRK00074
1034807003071	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1034807003072	AMP/PPi binding site [chemical binding]; other site
1034807003073	candidate oxyanion hole; other site
1034807003074	catalytic triad [active]
1034807003075	potential glutamine specificity residues [chemical binding]; other site
1034807003076	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1034807003077	ATP Binding subdomain [chemical binding]; other site
1034807003078	Ligand Binding sites [chemical binding]; other site
1034807003079	Dimerization subdomain; other site
1034807003080	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
1034807003081	D-ala-D-ala dipeptidase; Region: Peptidase_M15; cl00813
1034807003082	putative acyltransferase; Provisional; Region: PRK05790
1034807003083	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1034807003084	dimer interface [polypeptide binding]; other site
1034807003085	active site
1034807003086	Bacterial SH3 domain; Region: SH3_3; cl17532
1034807003087	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1034807003088	NlpC/P60 family; Region: NLPC_P60; pfam00877
1034807003089	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1034807003090	Beta-lactamase; Region: Beta-lactamase; pfam00144
1034807003091	bacillithiol system protein YtxJ; Region: B_thiol_YtxJ; TIGR04019
1034807003092	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1034807003093	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
1034807003094	Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436
1034807003095	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1034807003096	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034807003097	homodimer interface [polypeptide binding]; other site
1034807003098	catalytic residue [active]
1034807003099	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1034807003100	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
1034807003101	Predicted permeases [General function prediction only]; Region: COG0795
1034807003102	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1034807003103	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1034807003104	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
1034807003105	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
1034807003106	replicative DNA helicase; Region: DnaB; TIGR00665
1034807003107	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1034807003108	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1034807003109	Walker A motif; other site
1034807003110	ATP binding site [chemical binding]; other site
1034807003111	Walker B motif; other site
1034807003112	DNA binding loops [nucleotide binding]
1034807003113	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
1034807003114	Transposase domain (DUF772); Region: DUF772; pfam05598
1034807003115	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1034807003116	DDE superfamily endonuclease; Region: DDE_4; cl17710
1034807003117	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034807003118	non-specific DNA binding site [nucleotide binding]; other site
1034807003119	salt bridge; other site
1034807003120	sequence-specific DNA binding site [nucleotide binding]; other site
1034807003121	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1034807003122	DNA-methyltransferase (dcm); Region: dcm; TIGR00675
1034807003123	cofactor binding site; other site
1034807003124	DNA binding site [nucleotide binding]
1034807003125	substrate interaction site [chemical binding]; other site
1034807003126	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1034807003127	Superfamily of nucleases including Short Patch Repair (Vsr) Endonucleases, archaeal Holliday junction resolvases, MutH methy-directed DNA mismatch-repair endonucleases, and catalytic domains of many restriction endonucleases, such as EcoRI, BamHI, and...; Region: Restriction_endonuclease_like; cl00277
1034807003128	putative active site [active]
1034807003129	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
1034807003130	FAD binding domain; Region: FAD_binding_4; pfam01565
1034807003131	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1034807003132	Conserved hypothetical protein (DUF2461); Region: DUF2461; pfam09365
1034807003133	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1034807003134	active site residue [active]
1034807003135	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1034807003136	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1034807003137	catalytic residues [active]
1034807003138	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807003139	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
1034807003140	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1034807003141	DNA binding residues [nucleotide binding]
1034807003142	dimerization interface [polypeptide binding]; other site
1034807003143	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
1034807003144	starch binding outer membrane protein SusD; Region: SusD; cd08977
1034807003145	Laminarinase, member of the glycosyl hydrolase family 16; Region: GH16_laminarinase_like; cd08023
1034807003146	active site
1034807003147	catalytic residues [active]
1034807003148	Exonuclease-Endonuclease-Phosphatase domain; uncharacterized family 1; Region: EEP-1; cd09083
1034807003149	putative catalytic site [active]
1034807003150	putative metal binding site [ion binding]; other site
1034807003151	putative phosphate binding site [ion binding]; other site
1034807003152	O-Glycosyl hydrolase [Cell envelope biogenesis, outer membrane]; Region: COG5520
1034807003153	O-Glycosyl hydrolase family 30; Region: Glyco_hydro_30; pfam02055
1034807003154	O-Glycosyl hydrolase [Cell envelope biogenesis, outer membrane]; Region: COG5520
1034807003155	O-Glycosyl hydrolase family 30; Region: Glyco_hydro_30; pfam02055
1034807003156	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
1034807003157	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1034807003158	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
1034807003159	Peptidase M1 family containing bacterial Aminopeptidase N; Region: M1_APN_5; cd09604
1034807003160	Zn binding site [ion binding]; other site
1034807003161	Domain of unknown function (DUF3471); Region: DUF3471; pfam11954
1034807003162	Aldose 1-epimerase, similar to Lactococcus lactis lacX; Region: Aldose_epim_lacX; cd09024
1034807003163	active site
1034807003164	catalytic residues [active]
1034807003165	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1034807003166	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1034807003167	gliding motility-associated C-terminal domain; Region: Bac_Flav_CTERM; TIGR04131
1034807003168	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1034807003169	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034807003170	non-specific DNA binding site [nucleotide binding]; other site
1034807003171	salt bridge; other site
1034807003172	sequence-specific DNA binding site [nucleotide binding]; other site
1034807003173	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
1034807003174	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
1034807003175	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034807003176	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034807003177	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034807003178	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034807003179	Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type I periplasmic binding fold protein superfamily; Region: PBP1_ABC_transporter_LIVBP_like; cd06268
1034807003180	ligand binding site [chemical binding]; other site
1034807003181	OsmC-like protein; Region: OsmC; pfam02566
1034807003182	Protein of unknown function (DUF3820); Region: DUF3820; pfam12843
1034807003183	CTP synthetase; Validated; Region: pyrG; PRK05380
1034807003184	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1034807003185	Catalytic site [active]
1034807003186	active site
1034807003187	UTP binding site [chemical binding]; other site
1034807003188	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1034807003189	active site
1034807003190	putative oxyanion hole; other site
1034807003191	catalytic triad [active]
1034807003192	membrane protein insertase; Provisional; Region: PRK01318
1034807003193	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
1034807003194	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1034807003195	active site
1034807003196	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1034807003197	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1034807003198	active site
1034807003199	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1034807003200	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1034807003201	Glycosyltransferase like family; Region: Glyco_tranf_2_5; pfam13712
1034807003202	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1034807003203	active site
1034807003204	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
1034807003205	ketol-acid reductoisomerase; Validated; Region: PRK05225
1034807003206	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1034807003207	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1034807003208	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1034807003209	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1034807003210	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1034807003211	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1034807003212	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1034807003213	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1034807003214	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1034807003215	N-terminal plug; other site
1034807003216	ligand-binding site [chemical binding]; other site
1034807003217	GTP-binding protein YchF; Reviewed; Region: PRK09601
1034807003218	YchF GTPase; Region: YchF; cd01900
1034807003219	G1 box; other site
1034807003220	GTP/Mg2+ binding site [chemical binding]; other site
1034807003221	Switch I region; other site
1034807003222	G2 box; other site
1034807003223	Switch II region; other site
1034807003224	G3 box; other site
1034807003225	G4 box; other site
1034807003226	G5 box; other site
1034807003227	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1034807003228	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1034807003229	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034807003230	dimer interface [polypeptide binding]; other site
1034807003231	phosphorylation site [posttranslational modification]
1034807003232	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034807003233	ATP binding site [chemical binding]; other site
1034807003234	Mg2+ binding site [ion binding]; other site
1034807003235	G-X-G motif; other site
1034807003236	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034807003237	Response regulator receiver domain; Region: Response_reg; pfam00072
1034807003238	active site
1034807003239	phosphorylation site [posttranslational modification]
1034807003240	intermolecular recognition site; other site
1034807003241	dimerization interface [polypeptide binding]; other site
1034807003242	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
1034807003243	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034807003244	ATP binding site [chemical binding]; other site
1034807003245	Mg2+ binding site [ion binding]; other site
1034807003246	G-X-G motif; other site
1034807003247	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1034807003248	anchoring element; other site
1034807003249	dimer interface [polypeptide binding]; other site
1034807003250	ATP binding site [chemical binding]; other site
1034807003251	TOPRIM_TopoIIA_like: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to Saccharomyces cerevisiae Topoisomerase II. TopoIIA enzymes cut both strands...; Region: TOPRIM_TopoIIA_like; cd01030
1034807003252	active site
1034807003253	putative metal-binding site [ion binding]; other site
1034807003254	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1034807003255	Plasmid pRiA4b ORF-3-like protein; Region: PRiA4_ORF3; pfam07929
1034807003256	DNA topoisomerase IV subunit A; Provisional; Region: PRK12758
1034807003257	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cl00148
1034807003258	CAP-like domain; other site
1034807003259	active site
1034807003260	primary dimer interface [polypeptide binding]; other site
1034807003261	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1034807003262	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1034807003263	putative tRNA-binding site [nucleotide binding]; other site
1034807003264	B3/4 domain; Region: B3_4; pfam03483
1034807003265	tRNA synthetase B5 domain; Region: B5; pfam03484
1034807003266	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1034807003267	dimer interface [polypeptide binding]; other site
1034807003268	motif 1; other site
1034807003269	motif 3; other site
1034807003270	motif 2; other site
1034807003271	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1034807003272	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
1034807003273	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
1034807003274	Ligand binding site; other site
1034807003275	oligomer interface; other site
1034807003276	Phosphate transport regulator (distant homolog of PhoU) [Inorganic ion transport and metabolism]; Region: COG1392
1034807003277	Phosphate transporter family; Region: PHO4; pfam01384
1034807003278	Phosphate transporter family; Region: PHO4; pfam01384
1034807003279	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1034807003280	Putative esterase; Region: Esterase; pfam00756
1034807003281	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
1034807003282	Protein of unknown function (DUF721); Region: DUF721; pfam05258
1034807003283	Lipocalin-like domain; Region: Lipocalin_4; pfam13648
1034807003284	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034807003285	binding surface
1034807003286	TPR motif; other site
1034807003287	TPR repeat; Region: TPR_11; pfam13414
1034807003288	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034807003289	binding surface
1034807003290	TPR motif; other site
1034807003291	DNA gyrase subunit A; Validated; Region: PRK05560
1034807003292	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1034807003293	CAP-like domain; other site
1034807003294	active site
1034807003295	primary dimer interface [polypeptide binding]; other site
1034807003296	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1034807003297	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1034807003298	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1034807003299	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1034807003300	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1034807003301	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1034807003302	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Deinococcus radiodurans DR2231 protein and its bacterial homologs; Region: NTP-PPase_DR2231_like; cd11530
1034807003303	metal binding site [ion binding]; metal-binding site
1034807003304	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
1034807003305	hydrophobic ligand binding site; other site
1034807003306	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1034807003307	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1034807003308	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1034807003309	DNA binding residues [nucleotide binding]
1034807003310	16S rRNA methyltransferase B; Provisional; Region: PRK14902
1034807003311	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034807003312	S-adenosylmethionine binding site [chemical binding]; other site
1034807003313	Endonuclease I; Region: Endonuclease_1; pfam04231
1034807003314	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807003315	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
1034807003316	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
1034807003317	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1034807003318	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1034807003319	DNA binding residues [nucleotide binding]
1034807003320	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
1034807003321	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1034807003322	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034807003323	Walker A motif; other site
1034807003324	ATP binding site [chemical binding]; other site
1034807003325	Walker B motif; other site
1034807003326	arginine finger; other site
1034807003327	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1034807003328	glycine dehydrogenase; Provisional; Region: PRK05367
1034807003329	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1034807003330	tetramer interface [polypeptide binding]; other site
1034807003331	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034807003332	catalytic residue [active]
1034807003333	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1034807003334	tetramer interface [polypeptide binding]; other site
1034807003335	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034807003336	catalytic residue [active]
1034807003337	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1034807003338	S-adenosylmethionine binding site [chemical binding]; other site
1034807003339	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1034807003340	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1034807003341	Domain of unknown function (DUF4159); Region: DUF4159; pfam13709
1034807003342	16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713
1034807003343	RNA methyltransferase, RsmE family; Region: TIGR00046
1034807003344	UGMP family protein; Validated; Region: PRK09604
1034807003345	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1034807003346	Family of unknown function (DUF490); Region: DUF490; pfam04357
1034807003347	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
1034807003348	Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and...; Region: LbH_XAT; cd03349
1034807003349	trimer interface [polypeptide binding]; other site
1034807003350	active site
1034807003351	substrate binding site [chemical binding]; other site
1034807003352	CoA binding site [chemical binding]; other site
1034807003353	Translation initiation factor 2 (IF-2; GTPase) [Translation, ribosomal structure and biogenesis]; Region: InfB; COG0532
1034807003354	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1034807003355	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1034807003356	catalytic residues [active]
1034807003357	Protein of unknown function (DUF3738); Region: DUF3738; cl11887
1034807003358	Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282
1034807003359	Aerotolerance regulator N-terminal; Region: BatA; pfam07584
1034807003360	von Willebrand factor type A domain; Region: VWA_2; pfam13519
1034807003361	dihydroorotase; Validated; Region: pyrC; PRK09357
1034807003362	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
1034807003363	active site
1034807003364	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
1034807003365	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1034807003366	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1034807003367	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1034807003368	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1034807003369	gliding motility-associated C-terminal domain; Region: Bac_Flav_CTERM; TIGR04131
1034807003370	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
1034807003371	MutS domain III; Region: MutS_III; pfam05192
1034807003372	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034807003373	Walker A/P-loop; other site
1034807003374	ATP binding site [chemical binding]; other site
1034807003375	Q-loop/lid; other site
1034807003376	ABC transporter signature motif; other site
1034807003377	Walker B; other site
1034807003378	D-loop; other site
1034807003379	H-loop/switch region; other site
1034807003380	Predicted thiol-disulfide oxidoreductase [General function    prediction only]; Region: COG3011
1034807003381	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1034807003382	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1034807003383	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1034807003384	catalytic residue [active]
1034807003385	glycogen synthase; Provisional; Region: glgA; PRK00654
1034807003386	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
1034807003387	ADP-binding pocket [chemical binding]; other site
1034807003388	homodimer interface [polypeptide binding]; other site
1034807003389	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK02862
1034807003390	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
1034807003391	ligand binding site; other site
1034807003392	oligomer interface; other site
1034807003393	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
1034807003394	dimer interface [polypeptide binding]; other site
1034807003395	N-terminal domain interface [polypeptide binding]; other site
1034807003396	sulfate 1 binding site; other site
1034807003397	glycogen branching enzyme; Provisional; Region: PRK12313
1034807003398	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
1034807003399	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
1034807003400	active site
1034807003401	catalytic site [active]
1034807003402	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
1034807003403	phosphoribosylaminoimidazole synthetase; Region: purM; TIGR00878
1034807003404	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
1034807003405	dimerization interface [polypeptide binding]; other site
1034807003406	ATP binding site [chemical binding]; other site
1034807003407	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1034807003408	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1034807003409	putative enoyl-[acyl-carrier-protein] reductase II; Region: enACPred_II; TIGR03151
1034807003410	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
1034807003411	FMN binding site [chemical binding]; other site
1034807003412	substrate binding site [chemical binding]; other site
1034807003413	putative catalytic residue [active]
1034807003414	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1034807003415	phosphonoacetate hydrolase; Region: hydr_PhnA; TIGR02335
1034807003416	Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663
1034807003417	Inward rectifier potassium channel; Region: IRK; pfam01007
1034807003418	Predicted nuclease of restriction endonuclease-like fold, RmuC family [General function prediction only]; Region: COG1322
1034807003419	RmuC family; Region: RmuC; pfam02646
1034807003420	Uncharacterized protein related to glutamine synthetase [General function prediction only]; Region: COG3968
1034807003421	Glutamine synthetase type III N terminal; Region: GSIII_N; pfam12437
1034807003422	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1034807003423	exosortase A system-associated amidotransferase 1; Region: eps_aminotran_1; TIGR03108
1034807003424	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
1034807003425	active site
1034807003426	dimer interface [polypeptide binding]; other site
1034807003427	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
1034807003428	Ligand Binding Site [chemical binding]; other site
1034807003429	Molecular Tunnel; other site
1034807003430	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1034807003431	2-desacetyl-2-hydroxyethyl bacteriochlorophyllide and other MDR family members; Region: 2-desacetyl-2-hydroxyethyl_bacteriochlorophyllide_; cd08255
1034807003432	putative NAD(P) binding site [chemical binding]; other site
1034807003433	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1034807003434	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1034807003435	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1034807003436	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1034807003437	Walker A/P-loop; other site
1034807003438	ATP binding site [chemical binding]; other site
1034807003439	Q-loop/lid; other site
1034807003440	ABC transporter signature motif; other site
1034807003441	Walker B; other site
1034807003442	D-loop; other site
1034807003443	H-loop/switch region; other site
1034807003444	Domain of unknown function (DUF4349); Region: DUF4349; pfam14257
1034807003445	aminodeoxychorismate synthase, component I, clade 2; Region: PabB-clade2; TIGR01824
1034807003446	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1034807003447	AAA domain; Region: AAA_14; pfam13173
1034807003448	AAA domain; Region: AAA_22; pfam13401
1034807003449	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
1034807003450	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
1034807003451	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1034807003452	Ligand Binding Site [chemical binding]; other site
1034807003453	TilS substrate C-terminal domain; Region: TilS_C; smart00977
1034807003454	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034807003455	Thioredoxin-like domain; Region: Thioredoxin_2; pfam13098
1034807003456	Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; cl17312
1034807003457	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
1034807003458	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1034807003459	Alpha-glucosidase II (alpha-D-glucoside glucohydrolase) is a glycosyl hydrolase family 31 (GH31) enzyme, found in bacteria and plants, which has exo-alpha-1,4-glucosidase and oligo-1,6-glucosidase activities. Alpha-glucosidase II has been characterized...; Region: GH31_glucosidase_II_MalA; cd06604
1034807003460	trimer interface [polypeptide binding]; other site
1034807003461	active site
1034807003462	homohexamer (dimer of homotrimer) interface [polypeptide binding]; other site
1034807003463	catalytic site [active]
1034807003464	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
1034807003465	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034807003466	Mg2+ binding site [ion binding]; other site
1034807003467	G-X-G motif; other site
1034807003468	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1034807003469	anchoring element; other site
1034807003470	dimer interface [polypeptide binding]; other site
1034807003471	ATP binding site [chemical binding]; other site
1034807003472	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1034807003473	active site
1034807003474	putative metal-binding site [ion binding]; other site
1034807003475	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1034807003476	Dienelactone hydrolase family; Region: DLH; pfam01738
1034807003477	Uncharacterized protein conserved in bacteria (DUF2314); Region: DUF2314; pfam10077
1034807003478	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3779
1034807003479	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1034807003480	Ankyrin repeats (many copies); Region: Ank_5; pfam13857
1034807003481	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807003482	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1034807003483	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
1034807003484	active site
1034807003485	metal binding site [ion binding]; metal-binding site
1034807003486	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
1034807003487	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
1034807003488	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
1034807003489	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
1034807003490	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
1034807003491	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
1034807003492	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807003493	Lipocalin-like domain; Region: Lipocalin_4; pfam13648
1034807003494	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807003495	Predicted membrane protein [Function unknown]; Region: COG4682
1034807003496	yiaA/B two helix domain; Region: YiaAB; pfam05360
1034807003497	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1034807003498	active site
1034807003499	dimerization interface [polypeptide binding]; other site
1034807003500	helicase 45; Provisional; Region: PTZ00424
1034807003501	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1034807003502	ATP binding site [chemical binding]; other site
1034807003503	Mg++ binding site [ion binding]; other site
1034807003504	motif III; other site
1034807003505	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1034807003506	nucleotide binding region [chemical binding]; other site
1034807003507	ATP-binding site [chemical binding]; other site
1034807003508	RNA recognition motif in the DbpA subfamily of prokaryotic DEAD-box rRNA helicases; Region: RRM_DbpA; cd12252
1034807003509	RNA binding site [nucleotide binding]; other site
1034807003510	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1034807003511	C1 Peptidase family (MEROPS database nomenclature), also referred to as the papain family; composed of two subfamilies of cysteine peptidases (CPs), C1A (papain) and C1B (bleomycin hydrolase). Papain-like enzymes are mostly endopeptidases with some...; Region: Peptidase_C1; cl00298
1034807003512	active site
1034807003513	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1034807003514	HD domain; Region: HD_4; pfam13328
1034807003515	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1034807003516	synthetase active site [active]
1034807003517	NTP binding site [chemical binding]; other site
1034807003518	metal binding site [ion binding]; metal-binding site
1034807003519	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1034807003520	ACT domain; Region: ACT_4; pfam13291
1034807003521	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_24; cd09012
1034807003522	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1034807003523	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034807003524	AAA domain; Region: AAA_21; pfam13304
1034807003525	Walker A/P-loop; other site
1034807003526	ATP binding site [chemical binding]; other site
1034807003527	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
1034807003528	active site
1034807003529	Domain of unknown function (DUF1835); Region: DUF1835; pfam08874
1034807003530	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
1034807003531	Phosphoglycerate dehydrogenase (PGDH) NAD-binding and catalytic domains; Region: PGDH_2; cd05303
1034807003532	putative ligand binding site [chemical binding]; other site
1034807003533	NAD binding site [chemical binding]; other site
1034807003534	dimerization interface [polypeptide binding]; other site
1034807003535	catalytic site [active]
1034807003536	3-phosphoserine/phosphohydroxythreonine aminotransferase; Provisional; Region: PRK05355
1034807003537	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1034807003538	catalytic residue [active]
1034807003539	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
1034807003540	NAD(P) binding site [chemical binding]; other site
1034807003541	4Fe-4S binding domain; Region: Fer4; cl02805
1034807003542	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034807003543	putative substrate translocation pore; other site
1034807003544	glucose/galactose transporter; Region: gluP; TIGR01272
1034807003545	L-fucose transporter; Provisional; Region: PRK10133; cl17665
1034807003546	ornithine aminotransferase; Region: Orn_aminotrans; TIGR01885
1034807003547	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1034807003548	inhibitor-cofactor binding pocket; inhibition site
1034807003549	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034807003550	catalytic residue [active]
1034807003551	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
1034807003552	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
1034807003553	tetramer interface [polypeptide binding]; other site
1034807003554	TPP-binding site [chemical binding]; other site
1034807003555	heterodimer interface [polypeptide binding]; other site
1034807003556	phosphorylation loop region [posttranslational modification]
1034807003557	Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Region: TPP_enzyme_PYR; cl11410
1034807003558	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
1034807003559	PYR/PP interface [polypeptide binding]; other site
1034807003560	dimer interface [polypeptide binding]; other site
1034807003561	TPP binding site [chemical binding]; other site
1034807003562	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1034807003563	Heavy-metal-associated domain; Region: HMA; pfam00403
1034807003564	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1034807003565	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1034807003566	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1034807003567	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1034807003568	catalytic residues [active]
1034807003569	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
1034807003570	active site
1034807003571	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1034807003572	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
1034807003573	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
1034807003574	active site
1034807003575	substrate-binding site [chemical binding]; other site
1034807003576	metal-binding site [ion binding]
1034807003577	ATP binding site [chemical binding]; other site
1034807003578	Protein of unknown function (DUF423); Region: DUF423; pfam04241
1034807003579	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
1034807003580	catalytic residues [active]
1034807003581	dimer interface [polypeptide binding]; other site
1034807003582	ResB protein required for cytochrome c biosynthesis [Posttranslational modification, protein turnover, chaperones]; Region: ResB; cl09125
1034807003583	Predicted acyltransferases [Lipid metabolism]; Region: COG1835
1034807003584	cytochrome c-type biogenesis protein CcsB; Region: cytochr_II_ccsB; TIGR03144
1034807003585	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1034807003586	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ABO13168; Region: LPLAT_ABO13168-like; cd07988
1034807003587	putative acyl-acceptor binding pocket; other site
1034807003588	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1034807003589	GLPGLI family protein; Region: GLPGLI; TIGR01200
1034807003590	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
1034807003591	TPP-binding site [chemical binding]; other site
1034807003592	tetramer interface [polypeptide binding]; other site
1034807003593	heterodimer interface [polypeptide binding]; other site
1034807003594	phosphorylation loop region [posttranslational modification]
1034807003595	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
1034807003596	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
1034807003597	alpha subunit interface [polypeptide binding]; other site
1034807003598	TPP binding site [chemical binding]; other site
1034807003599	heterodimer interface [polypeptide binding]; other site
1034807003600	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1034807003601	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
1034807003602	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
1034807003603	homodimer interface [polypeptide binding]; other site
1034807003604	substrate-cofactor binding pocket; other site
1034807003605	catalytic residue [active]
1034807003606	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
1034807003607	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1034807003608	E3 interaction surface; other site
1034807003609	lipoyl attachment site [posttranslational modification]; other site
1034807003610	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1034807003611	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
1034807003612	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1034807003613	substrate binding site [chemical binding]; other site
1034807003614	oxyanion hole (OAH) forming residues; other site
1034807003615	trimer interface [polypeptide binding]; other site
1034807003616	bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; Provisional; Region: PRK11563
1034807003617	N-terminal domain of the monoamine oxidase C dehydratase; Region: ALDH_MaoC-N; cd07128
1034807003618	substrate binding site [chemical binding]; other site
1034807003619	dimer interface [polypeptide binding]; other site
1034807003620	NADP binding site [chemical binding]; other site
1034807003621	catalytic residues [active]
1034807003622	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
1034807003623	active site 2 [active]
1034807003624	active site 1 [active]
1034807003625	beta-ketoadipyl CoA thiolase; Validated; Region: PRK09050
1034807003626	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
1034807003627	dimer interface [polypeptide binding]; other site
1034807003628	active site
1034807003629	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
1034807003630	CoenzymeA binding site [chemical binding]; other site
1034807003631	subunit interaction site [polypeptide binding]; other site
1034807003632	PHB binding site; other site
1034807003633	3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Region: FadB; COG1250
1034807003634	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1034807003635	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1034807003636	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1034807003637	enoyl-CoA hydratase; Provisional; Region: PRK08140
1034807003638	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
1034807003639	substrate binding site [chemical binding]; other site
1034807003640	oxyanion hole (OAH) forming residues; other site
1034807003641	trimer interface [polypeptide binding]; other site
1034807003642	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
1034807003643	phenylacetate-CoA oxygenase, PaaJ subunit; Region: PA_CoA_Oxy4; TIGR02159
1034807003644	Phenylacetic acid catabolic protein; Region: PaaA_PaaC; pfam05138
1034807003645	phenylacetate-CoA oxygenase subunit PaaB; Provisional; Region: paaB; PRK13781
1034807003646	phenylacetate-CoA oxygenase subunit PaaA; Provisional; Region: paaA; PRK13778
1034807003647	phenylacetate-CoA oxygenase, PaaG subunit; Region: PA_CoA_Oxy1; TIGR02156
1034807003648	phenylacetate-CoA oxygenase/reductase, PaaK subunit; Region: PA_CoA_Oxy5; TIGR02160
1034807003649	NAD(P) binding domain of ferredoxin reductase like phenylacetic acid (PA) degradation oxidoreductase. PA oxidoreductases of E. coli hydroxylate PA-CoA in the second step of PA degradation. Members of this group typically fuse a ferredoxin reductase-like...; Region: PA_degradation_oxidoreductase_like; cd06214
1034807003650	FAD binding pocket [chemical binding]; other site
1034807003651	FAD binding motif [chemical binding]; other site
1034807003652	phosphate binding motif [ion binding]; other site
1034807003653	beta-alpha-beta structure motif; other site
1034807003654	NAD(p) ribose binding residues [chemical binding]; other site
1034807003655	NAD binding pocket [chemical binding]; other site
1034807003656	NAD(P)-pyrophosphate-nicotinamide binding residues [chemical binding]; other site
1034807003657	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1034807003658	catalytic loop [active]
1034807003659	iron binding site [ion binding]; other site
1034807003660	Predicted Fe-S-cluster redox enzyme [General function prediction only]; Region: COG0820
1034807003661	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1034807003662	FeS/SAM binding site; other site
1034807003663	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
1034807003664	active site
1034807003665	metal binding site [ion binding]; metal-binding site
1034807003666	homotetramer interface [polypeptide binding]; other site
1034807003667	Domain of unknown function (DUF4293); Region: DUF4293; pfam14126
1034807003668	Rho termination factor, N-terminal domain; Region: Rho_N; cl06505
1034807003669	transcription termination factor Rho; Provisional; Region: PRK12608
1034807003670	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1034807003671	RNA binding site [nucleotide binding]; other site
1034807003672	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1034807003673	multimer interface [polypeptide binding]; other site
1034807003674	Walker A motif; other site
1034807003675	ATP binding site [chemical binding]; other site
1034807003676	Walker B motif; other site
1034807003677	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1034807003678	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1034807003679	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1034807003680	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
1034807003681	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
1034807003682	dimer interface [polypeptide binding]; other site
1034807003683	M28 Zn-Peptidases containing a PA domain insert; Region: M28_like_PA; cd03877
1034807003684	Peptidase family M28; Region: Peptidase_M28; pfam04389
1034807003685	metal binding site [ion binding]; metal-binding site
1034807003686	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1034807003687	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_d; cd04196
1034807003688	Probable Catalytic site; other site
1034807003689	Protein of unknown function (DUF2029); Region: DUF2029; pfam09594
1034807003690	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1034807003691	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1034807003692	Ligand binding site; other site
1034807003693	Putative Catalytic site; other site
1034807003694	DXD motif; other site
1034807003695	Putative catalytic domain of uncharacterized prokaryotic polysaccharide deacetylases similar to bacterial PuuE allantoinases and Helicobacter pylori peptidoglycan deacetylase (HpPgdA); Region: CE4_PuuE_HpPgdA_like_2; cd10941
1034807003696	putative active site [active]
1034807003697	putative catalytic site [active]
1034807003698	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1034807003699	N-terminal domain of Chondroitin polymerase functions as a GalNAc transferase; Region: GT2_Chondriotin_Pol_N; cd06420
1034807003700	Substrate binding site; other site
1034807003701	metal-binding site
1034807003702	Glycosyltransferase like family; Region: Glyco_tranf_2_5; pfam13712
1034807003703	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
1034807003704	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
1034807003705	Probable Catalytic site; other site
1034807003706	metal-binding site
1034807003707	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1034807003708	active site
1034807003709	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1034807003710	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
1034807003711	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
1034807003712	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
1034807003713	trimer interface [polypeptide binding]; other site
1034807003714	active site
1034807003715	substrate binding site [chemical binding]; other site
1034807003716	CoA binding site [chemical binding]; other site
1034807003717	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
1034807003718	oligomerization interface [polypeptide binding]; other site
1034807003719	active site
1034807003720	metal binding site [ion binding]; metal-binding site
1034807003721	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1034807003722	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1034807003723	active site
1034807003724	Bacillus subtilis aldehyde dehydrogenase ywdH-like; Region: ALDH_YwdH-P39616; cd07136
1034807003725	NAD(P) binding site [chemical binding]; other site
1034807003726	catalytic residues [active]
1034807003727	PAS domain; Region: PAS; smart00091
1034807003728	PAS domain; Region: PAS_9; pfam13426
1034807003729	PAS domain S-box; Region: sensory_box; TIGR00229
1034807003730	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1034807003731	putative active site [active]
1034807003732	heme pocket [chemical binding]; other site
1034807003733	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1034807003734	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1034807003735	PAS domain S-box; Region: sensory_box; TIGR00229
1034807003736	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1034807003737	putative active site [active]
1034807003738	heme pocket [chemical binding]; other site
1034807003739	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034807003740	dimer interface [polypeptide binding]; other site
1034807003741	phosphorylation site [posttranslational modification]
1034807003742	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034807003743	ATP binding site [chemical binding]; other site
1034807003744	Mg2+ binding site [ion binding]; other site
1034807003745	G-X-G motif; other site
1034807003746	Response regulator receiver domain; Region: Response_reg; pfam00072
1034807003747	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034807003748	active site
1034807003749	phosphorylation site [posttranslational modification]
1034807003750	intermolecular recognition site; other site
1034807003751	dimerization interface [polypeptide binding]; other site
1034807003752	Predicted metalloprotease [General function prediction only]; Region: COG2321
1034807003753	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
1034807003754	3-hydroxy-3-methylglutaryl CoA synthase [Lipid metabolism]; Region: PksG; COG3425
1034807003755	"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827
1034807003756	dimer interface [polypeptide binding]; other site
1034807003757	active site
1034807003758	hypothetical protein; Validated; Region: PRK02101
1034807003759	Dienelactone hydrolase family; Region: DLH; pfam01738
1034807003760	Domain of unknown function (DU1801); Region: DUF1801; pfam08818
1034807003761	Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002
1034807003762	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
1034807003763	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1034807003764	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
1034807003765	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1034807003766	active site
1034807003767	peptide chain release factor 2; Validated; Region: prfB; PRK00578
1034807003768	PCRF domain; Region: PCRF; pfam03462
1034807003769	RF-1 domain; Region: RF-1; pfam00472
1034807003770	Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692
1034807003771	adenylosuccinate lyase; Provisional; Region: PRK09285
1034807003772	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
1034807003773	tetramer interface [polypeptide binding]; other site
1034807003774	active site
1034807003775	NAD-dependent deacetylase; Provisional; Region: PRK00481
1034807003776	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
1034807003777	NAD+ binding site [chemical binding]; other site
1034807003778	substrate binding site [chemical binding]; other site
1034807003779	Zn binding site [ion binding]; other site
1034807003780	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1034807003781	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1034807003782	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
1034807003783	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1034807003784	Acyl CoA binding protein; Region: ACBP; pfam00887
1034807003785	acyl-CoA binding pocket [chemical binding]; other site
1034807003786	CoA binding site [chemical binding]; other site
1034807003787	phosphatidylserine decarboxylase; Provisional; Region: PRK05305
1034807003788	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
1034807003789	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1034807003790	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; cl00674
1034807003791	FtsH Extracellular; Region: FtsH_ext; pfam06480
1034807003792	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
1034807003793	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034807003794	Walker A motif; other site
1034807003795	ATP binding site [chemical binding]; other site
1034807003796	Walker B motif; other site
1034807003797	arginine finger; other site
1034807003798	Peptidase family M41; Region: Peptidase_M41; pfam01434
1034807003799	iojap-like ribosome-associated protein; Region: iojap_ybeB; TIGR00090
1034807003800	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
1034807003801	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
1034807003802	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
1034807003803	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
1034807003804	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
1034807003805	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
1034807003806	Domain of Unknown Function (DUF349); Region: DUF349; pfam03993
1034807003807	ribonuclease Z; Reviewed; Region: PRK00055
1034807003808	putative voltage-gated ClC-type chloride channel ClcB; Provisional; Region: PRK01862
1034807003809	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
1034807003810	Cl- selectivity filter; other site
1034807003811	Cl- binding residues [ion binding]; other site
1034807003812	pore gating glutamate residue; other site
1034807003813	dimer interface [polypeptide binding]; other site
1034807003814	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with either the SpoIVFB domain (sporulation protein, stage IV cell wall formation, F locus, promoter-distal B) or the chloride channel protein EriC; Region: CBS_pair_SpoIVFB_EriC_assoc2; cd04613
1034807003815	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1034807003816	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
1034807003817	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1034807003818	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
1034807003819	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
1034807003820	dimerization interface [polypeptide binding]; other site
1034807003821	ATP binding site [chemical binding]; other site
1034807003822	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
1034807003823	dimerization interface [polypeptide binding]; other site
1034807003824	ATP binding site [chemical binding]; other site
1034807003825	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
1034807003826	putative active site [active]
1034807003827	catalytic triad [active]
1034807003828	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
1034807003829	tandem repeat interface [polypeptide binding]; other site
1034807003830	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
1034807003831	oligomer interface [polypeptide binding]; other site
1034807003832	active site residues [active]
1034807003833	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
1034807003834	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1034807003835	tandem repeat interface [polypeptide binding]; other site
1034807003836	oligomer interface [polypeptide binding]; other site
1034807003837	active site residues [active]
1034807003838	DNA polymerase III subunits gamma and tau; Provisional; Region: PRK14970
1034807003839	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034807003840	Walker A motif; other site
1034807003841	ATP binding site [chemical binding]; other site
1034807003842	Walker B motif; other site
1034807003843	arginine finger; other site
1034807003844	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
1034807003845	DNA polymerase III subunits gamma and tau; Provisional; Region: PRK14971
1034807003846	META domain; Region: META; pfam03724
1034807003847	dihydrolipoamide dehydrogenase; Validated; Region: PRK06327
1034807003848	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
1034807003849	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1034807003850	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1034807003851	non-metazoan 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_Sc; cd01414
1034807003852	ATP binding site [chemical binding]; other site
1034807003853	active site
1034807003854	substrate binding site [chemical binding]; other site
1034807003855	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_6; cd06154
1034807003856	homotrimer interaction site [polypeptide binding]; other site
1034807003857	putative active site [active]
1034807003858	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1034807003859	active site
1034807003860	UDP-N-acetylglucosamine 2-epimerase; Region: Epimerase_2; pfam02350
1034807003861	homodimer interface [polypeptide binding]; other site
1034807003862	Heparinase II/III-like protein; Region: Hepar_II_III; pfam07940
1034807003863	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
1034807003864	putative glycosyl transferase; Provisional; Region: PRK10307
1034807003865	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1034807003866	Putative Acyltransferase (AT), Left-handed parallel beta-Helix (LbH) domain; This group is composed of mostly uncharacterized proteins containing an N-terminal helical subdomain followed by a LbH domain. The alignment contains 6 turns, each containing...; Region: LbH_AT_putative; cd03360
1034807003867	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; Region: NeuD_NnaD; TIGR03570
1034807003868	putative trimer interface [polypeptide binding]; other site
1034807003869	putative CoA binding site [chemical binding]; other site
1034807003870	Bacterial sugar transferase; Region: Bac_transf; cl00939
1034807003871	aminotransferase, LLPSF_NHT_00031 family; Region: NHT_00031; TIGR04181
1034807003872	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1034807003873	inhibitor-cofactor binding pocket; inhibition site
1034807003874	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034807003875	catalytic residue [active]
1034807003876	Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086
1034807003877	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
1034807003878	NAD(P) binding site [chemical binding]; other site
1034807003879	homodimer interface [polypeptide binding]; other site
1034807003880	substrate binding site [chemical binding]; other site
1034807003881	active site
1034807003882	putative polysaccharide export protein, PEP-CTERM sytem-associated; Region: pepcterm_export; TIGR03027
1034807003883	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1034807003884	SLBB domain; Region: SLBB; pfam10531
1034807003885	Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane]; Region: GumC; COG3206
1034807003886	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
1034807003887	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1034807003888	Capsular polysaccharide biosynthesis protein [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: CapC; COG4464
1034807003889	PQQ-dependent catabolism-associated beta-propeller protein; Region: PQQ_ABC_repeats; TIGR03866
1034807003890	Outer membrane protein/protective antigen OMA87 [Cell envelope biogenesis, outer membrane]; Region: COG4775
1034807003891	Protein of unknown function (DUF2721); Region: DUF2721; pfam11026
1034807003892	Nicotinate-nucleotide pyrophosphorylase [Coenzyme metabolism]; Region: NadC; COG0157
1034807003893	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
1034807003894	dimerization interface [polypeptide binding]; other site
1034807003895	active site
1034807003896	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
1034807003897	Uncharacterized protein conserved in bacteria (DUF2147); Region: DUF2147; pfam09917
1034807003898	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1034807003899	primosomal protein N' Region: priA; TIGR00595
1034807003900	ATP binding site [chemical binding]; other site
1034807003901	putative Mg++ binding site [ion binding]; other site
1034807003902	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1034807003903	ATP-binding site [chemical binding]; other site
1034807003904	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1034807003905	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034807003906	active site
1034807003907	phosphorylation site [posttranslational modification]
1034807003908	intermolecular recognition site; other site
1034807003909	dimerization interface [polypeptide binding]; other site
1034807003910	LytTr DNA-binding domain; Region: LytTR; smart00850
1034807003911	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1034807003912	dimerization interface [polypeptide binding]; other site
1034807003913	putative DNA binding site [nucleotide binding]; other site
1034807003914	putative Zn2+ binding site [ion binding]; other site
1034807003915	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
1034807003916	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
1034807003917	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1034807003918	ligand binding site [chemical binding]; other site
1034807003919	active site
1034807003920	UGI interface [polypeptide binding]; other site
1034807003921	catalytic site [active]
1034807003922	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
1034807003923	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1034807003924	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034807003925	Walker A motif; other site
1034807003926	ATP binding site [chemical binding]; other site
1034807003927	Walker B motif; other site
1034807003928	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
1034807003929	Pleckstrin homology (PH)-like domains in bacteria (PHb); Region: PH-like_bacteria; cd13225
1034807003930	pentamer interface [polypeptide binding]; other site
1034807003931	dodecaamer interface [polypeptide binding]; other site
1034807003932	deoxyhypusine synthase; Region: dhys; TIGR00321
1034807003933	Deoxyhypusine synthase; Region: DS; cl00826
1034807003934	Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019
1034807003935	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
1034807003936	dimer interface [polypeptide binding]; other site
1034807003937	active site
1034807003938	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1034807003939	catalytic residues [active]
1034807003940	substrate binding site [chemical binding]; other site
1034807003941	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1034807003942	active site
1034807003943	dimer interface [polypeptide binding]; other site
1034807003944	metal binding site [ion binding]; metal-binding site
1034807003945	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
1034807003946	malate:quinone oxidoreductase; Validated; Region: PRK05257
1034807003947	malate:quinone-oxidoreductase; Region: mal_quin_oxido; TIGR01320
1034807003948	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1034807003949	active site
1034807003950	catalytic residues [active]
1034807003951	metal binding site [ion binding]; metal-binding site
1034807003952	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
1034807003953	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
1034807003954	homodimer interface [polypeptide binding]; other site
1034807003955	metal binding site [ion binding]; metal-binding site
1034807003956	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
1034807003957	homodimer interface [polypeptide binding]; other site
1034807003958	active site
1034807003959	putative chemical substrate binding site [chemical binding]; other site
1034807003960	metal binding site [ion binding]; metal-binding site
1034807003961	pyridoxamine-phosphate oxidase; Region: pdxH; TIGR00558
1034807003962	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
1034807003963	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
1034807003964	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
1034807003965	catalytic core [active]
1034807003966	polyphosphate kinase; Provisional; Region: PRK05443
1034807003967	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
1034807003968	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
1034807003969	Catalytic C-terminal domain, first repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C1_like; cd09164
1034807003970	domain interface [polypeptide binding]; other site
1034807003971	active site
1034807003972	catalytic site [active]
1034807003973	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
1034807003974	domain interface [polypeptide binding]; other site
1034807003975	active site
1034807003976	catalytic site [active]
1034807003977	exopolyphosphatase; Region: exo_poly_only; TIGR03706
1034807003978	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1034807003979	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1034807003980	active site
1034807003981	catalytic site [active]
1034807003982	substrate binding site [chemical binding]; other site
1034807003983	Predicted signal-transduction protein containing cAMP-binding and CBS domains [Signal transduction mechanisms]; Region: COG2905
1034807003984	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1034807003985	ligand binding site [chemical binding]; other site
1034807003986	flexible hinge region; other site
1034807003987	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with either the CAP_ED (cAMP receptor protein effector domain) family of transcription factors and the DUF294 domain or the PB1 (Phox and Bem1p) domain; Region: CBS_pair_CAP-ED_DUF294_PBI_assoc2; cd04800
1034807003988	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
1034807003989	metal binding triad; other site
1034807003990	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I_II_III; cd09638
1034807003991	CRISPR spacer
1034807003992	CRISPR spacer
1034807003993	CRISPR spacer
1034807003994	CRISPR spacer
1034807003995	CRISPR spacer
1034807003996	CRISPR spacer
1034807003997	CRISPR spacer
1034807003998	CRISPR spacer
1034807003999	CRISPR spacer
1034807004000	CRISPR spacer
1034807004001	CRISPR spacer
1034807004002	CRISPR spacer
1034807004003	CRISPR spacer
1034807004004	CRISPR spacer
1034807004005	CRISPR spacer
1034807004006	CRISPR spacer
1034807004007	CRISPR spacer
1034807004008	CRISPR spacer
1034807004009	CRISPR spacer
1034807004010	CRISPR spacer
1034807004011	CRISPR spacer
1034807004012	CRISPR spacer
1034807004013	CRISPR spacer
1034807004014	CRISPR spacer
1034807004015	CRISPR spacer
1034807004016	CRISPR spacer
1034807004017	CRISPR spacer
1034807004018	Uncharacterized protein family (UPF0156); Region: RHH_2; cl17383
1034807004019	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034807004020	non-specific DNA binding site [nucleotide binding]; other site
1034807004021	salt bridge; other site
1034807004022	sequence-specific DNA binding site [nucleotide binding]; other site
1034807004023	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cl00083
1034807004024	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cl00083
1034807004025	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1034807004026	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1034807004027	ATP binding site [chemical binding]; other site
1034807004028	putative Mg++ binding site [ion binding]; other site
1034807004029	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1034807004030	nucleotide binding region [chemical binding]; other site
1034807004031	ATP-binding site [chemical binding]; other site
1034807004032	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1034807004033	ATP binding site [chemical binding]; other site
1034807004034	putative Mg++ binding site [ion binding]; other site
1034807004035	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1034807004036	nucleotide binding region [chemical binding]; other site
1034807004037	ATP-binding site [chemical binding]; other site
1034807004038	Domain of unknown function (DUF3817); Region: DUF3817; pfam12823
1034807004039	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1034807004040	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1034807004041	Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins; Region: SRPBCC_3; cd07820
1034807004042	putative hydrophobic ligand binding site [chemical binding]; other site
1034807004043	Deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair]; Region: PhrB; COG0415
1034807004044	DNA photolyase; Region: DNA_photolyase; pfam00875
1034807004045	Sortase and related acyltransferases [Cell envelope biogenesis, outer membrane]; Region: COG1247
1034807004046	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1034807004047	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
1034807004048	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1034807004049	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1034807004050	active site
1034807004051	HIGH motif; other site
1034807004052	nucleotide binding site [chemical binding]; other site
1034807004053	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1034807004054	KMSKS motif; other site
1034807004055	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1034807004056	tRNA binding surface [nucleotide binding]; other site
1034807004057	anticodon binding site; other site
1034807004058	GTP cyclohydrolase I; Provisional; Region: folE; PRK09347
1034807004059	GTP cyclohydrolase I; Provisional; Region: PLN03044
1034807004060	active site
1034807004061	Isopenicillin N synthase and related dioxygenases [General function prediction only]; Region: PcbC; COG3491
1034807004062	non-haem dioxygenase in morphine synthesis N-terminal; Region: DIOX_N; pfam14226
1034807004063	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy; pfam03171
1034807004064	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1034807004065	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_16; cd07263
1034807004066	Uncharacterized conserved protein [Function unknown]; Region: COG1359
1034807004067	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
1034807004068	putative rRNA binding site [nucleotide binding]; other site
1034807004069	uridine phosphorylase; Provisional; Region: PRK11178
1034807004070	Phosphorylase superfamily; Region: PNP_UDP_1; pfam01048
1034807004071	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1034807004072	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
1034807004073	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
1034807004074	quinone interaction residues [chemical binding]; other site
1034807004075	active site
1034807004076	catalytic residues [active]
1034807004077	FMN binding site [chemical binding]; other site
1034807004078	substrate binding site [chemical binding]; other site
1034807004079	3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain; Region: DRE_TIM_HMGL; cd07938
1034807004080	active site
1034807004081	catalytic residues [active]
1034807004082	metal binding site [ion binding]; metal-binding site
1034807004083	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
1034807004084	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
1034807004085	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1034807004086	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1034807004087	Possible lysine decarboxylase; Region: Lysine_decarbox; cl00695
1034807004088	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
1034807004089	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
1034807004090	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
1034807004091	metal binding site [ion binding]; metal-binding site
1034807004092	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
1034807004093	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1034807004094	substrate binding site [chemical binding]; other site
1034807004095	glutamase interaction surface [polypeptide binding]; other site
1034807004096	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
1034807004097	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
1034807004098	catalytic residues [active]
1034807004099	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13181
1034807004100	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
1034807004101	putative active site [active]
1034807004102	oxyanion strand; other site
1034807004103	catalytic triad [active]
1034807004104	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
1034807004105	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034807004106	active site
1034807004107	motif I; other site
1034807004108	motif II; other site
1034807004109	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
1034807004110	putative active site pocket [active]
1034807004111	4-fold oligomerization interface [polypeptide binding]; other site
1034807004112	metal binding residues [ion binding]; metal-binding site
1034807004113	3-fold/trimer interface [polypeptide binding]; other site
1034807004114	histidinol-phosphate aminotransferase; Region: hisC; TIGR01141
1034807004115	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1034807004116	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034807004117	homodimer interface [polypeptide binding]; other site
1034807004118	catalytic residue [active]
1034807004119	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
1034807004120	histidinol dehydrogenase; Region: hisD; TIGR00069
1034807004121	NAD binding site [chemical binding]; other site
1034807004122	dimerization interface [polypeptide binding]; other site
1034807004123	product binding site; other site
1034807004124	substrate binding site [chemical binding]; other site
1034807004125	zinc binding site [ion binding]; other site
1034807004126	catalytic residues [active]
1034807004127	Mannose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Region: {ManC}; COG0662
1034807004128	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
1034807004129	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
1034807004130	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
1034807004131	DinB superfamily; Region: DinB_2; pfam12867
1034807004132	Phosphoenolpyruvate carboxylase; Region: PEPcase; cl17418
1034807004133	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
1034807004134	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1034807004135	putative DNA binding site [nucleotide binding]; other site
1034807004136	putative Zn2+ binding site [ion binding]; other site
1034807004137	AsnC family; Region: AsnC_trans_reg; pfam01037
1034807004138	Peptidase M14-like domain; uncharacterized subgroup; Region: M14-like_1_2; cd06239
1034807004139	putative active site [active]
1034807004140	Zn binding site [ion binding]; other site
1034807004141	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034807004142	non-specific DNA binding site [nucleotide binding]; other site
1034807004143	salt bridge; other site
1034807004144	sequence-specific DNA binding site [nucleotide binding]; other site
1034807004145	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
1034807004146	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
1034807004147	RNA binding site [nucleotide binding]; other site
1034807004148	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1034807004149	RNA binding site [nucleotide binding]; other site
1034807004150	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
1034807004151	RNA binding site [nucleotide binding]; other site
1034807004152	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1034807004153	RNA binding site [nucleotide binding]; other site
1034807004154	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1034807004155	RNA binding site [nucleotide binding]; other site
1034807004156	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1034807004157	Vault protein inter-alpha-trypsin domain; Region: VIT; cl02699
1034807004158	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1034807004159	FAD binding domain; Region: FAD_binding_4; pfam01565
1034807004160	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1034807004161	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
1034807004162	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1034807004163	ATP binding site [chemical binding]; other site
1034807004164	putative Mg++ binding site [ion binding]; other site
1034807004165	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1034807004166	nucleotide binding region [chemical binding]; other site
1034807004167	ATP-binding site [chemical binding]; other site
1034807004168	DbpA RNA binding domain; Region: DbpA; pfam03880
1034807004169	Diadenosine hexaphosphate (Ap6A) hydrolase is a member of the Nudix hydrolase superfamily. Ap6A hydrolase specifically hydrolyzes diadenosine polyphosphates, but not ATP or diadenosine triphosphate, and it generates ATP as the product. Ap6A, the most...; Region: Ap6A_hydrolase; cd03673
1034807004170	active site
1034807004171	Ap6A binding site [chemical binding]; other site
1034807004172	nudix motif; other site
1034807004173	metal binding site [ion binding]; metal-binding site
1034807004174	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1034807004175	active site
1034807004176	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
1034807004177	active site
1034807004178	intersubunit interactions; other site
1034807004179	catalytic residue [active]
1034807004180	short chain dehydrogenase; Provisional; Region: PRK06179
1034807004181	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
1034807004182	NADP binding site [chemical binding]; other site
1034807004183	active site
1034807004184	steroid binding site; other site
1034807004185	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
1034807004186	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1034807004187	DegT/DnrJ/EryC1/StrS aminotransferase family; Region: DegT_DnrJ_EryC1; pfam01041
1034807004188	inhibitor-cofactor binding pocket; inhibition site
1034807004189	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034807004190	catalytic residue [active]
1034807004191	RDD family; Region: RDD; pfam06271
1034807004192	Integral membrane protein DUF95; Region: DUF95; pfam01944
1034807004193	Domain of unknown function (DUF4350); Region: DUF4350; pfam14258
1034807004194	MoxR-like ATPases [General function prediction only]; Region: COG0714
1034807004195	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034807004196	Walker A motif; other site
1034807004197	ATP binding site [chemical binding]; other site
1034807004198	Walker B motif; other site
1034807004199	arginine finger; other site
1034807004200	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
1034807004201	Protein of unknown function DUF58; Region: DUF58; pfam01882
1034807004202	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
1034807004203	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
1034807004204	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1034807004205	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cl00264
1034807004206	dinuclear metal binding motif [ion binding]; other site
1034807004207	Nodulin-21 and CCC1-related protein family; Region: Nodulin-21_like_2; cd02433
1034807004208	HlyD family secretion protein; Region: HlyD_2; pfam12700
1034807004209	HlyD family secretion protein; Region: HlyD_3; pfam13437
1034807004210	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
1034807004211	Outer membrane efflux protein; Region: OEP; pfam02321
1034807004212	Outer membrane efflux protein; Region: OEP; pfam02321
1034807004213	Domain of unknown function (DUF2520); Region: DUF2520; pfam10728
1034807004214	HAD-superfamily hydrolase, subfamily IIIA; Region: HAD-SF-IIIA; TIGR01662
1034807004215	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034807004216	active site
1034807004217	motif I; other site
1034807004218	motif II; other site
1034807004219	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
1034807004220	Maf-like protein; Region: Maf; pfam02545
1034807004221	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1034807004222	active site
1034807004223	dimer interface [polypeptide binding]; other site
1034807004224	uncharacterized subgroup of the Na(+)/iodide (NIS) cotransporter subfamily; putative solute-binding domain; Region: SLC5sbd_NIS-like_u2; cd11494
1034807004225	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
1034807004226	Na binding site [ion binding]; other site
1034807004227	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
1034807004228	Sulfatase; Region: Sulfatase; pfam00884
1034807004229	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
1034807004230	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1034807004231	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
1034807004232	dimerization interface [polypeptide binding]; other site
1034807004233	Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]; Region: CtaA; COG1612
1034807004234	Cytochrome oxidase assembly protein; Region: COX15-CtaA; pfam02628
1034807004235	tRNA adenylyltransferase; Region: tRNA_CCA_actino; TIGR02692
1034807004236	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1034807004237	active site
1034807004238	NTP binding site [chemical binding]; other site
1034807004239	metal binding triad [ion binding]; metal-binding site
1034807004240	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1034807004241	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1034807004242	Zn2+ binding site [ion binding]; other site
1034807004243	Mg2+ binding site [ion binding]; other site
1034807004244	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
1034807004245	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
1034807004246	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1034807004247	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1034807004248	Domain of unknown function (DUF4369); Region: DUF4369; pfam14289
1034807004249	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1034807004250	HSP70 interaction site [polypeptide binding]; other site
1034807004251	KTSC domain; Region: KTSC; pfam13619
1034807004252	S1 domain; Region: S1_2; pfam13509
1034807004253	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1034807004254	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1034807004255	dimer interface [polypeptide binding]; other site
1034807004256	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034807004257	catalytic residue [active]
1034807004258	Protease II [Amino acid transport and metabolism]; Region: PtrB; COG1770
1034807004259	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1034807004260	YbaB/EbfC DNA-binding family; Region: YbaB_DNA_bd; cl00494
1034807004261	L,D-transpeptidase catalytic domain; Region: YkuD_2; pfam13645
1034807004262	hypothetical protein; Provisional; Region: PRK10621
1034807004263	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1034807004264	Patatin-like phospholipase; Region: Patatin; pfam01734
1034807004265	active site
1034807004266	nucleophile elbow; other site
1034807004267	Peptidase M1 family Aminopeptidase N; Region: M1_APN_4; cd09603
1034807004268	Zn binding site [ion binding]; other site
1034807004269	Putative metal-binding domain of cation transport ATPase; Region: ATPase-cat_bd; pfam12156
1034807004270	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1034807004271	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1034807004272	metal-binding site [ion binding]
1034807004273	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1034807004274	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034807004275	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1034807004276	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1034807004277	ligand binding site [chemical binding]; other site
1034807004278	flexible hinge region; other site
1034807004279	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
1034807004280	putative switch regulator; other site
1034807004281	non-specific DNA interactions [nucleotide binding]; other site
1034807004282	DNA binding site [nucleotide binding]
1034807004283	sequence specific DNA binding site [nucleotide binding]; other site
1034807004284	putative cAMP binding site [chemical binding]; other site
1034807004285	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
1034807004286	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019
1034807004287	Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999
1034807004288	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
1034807004289	Cu(I) binding site [ion binding]; other site
1034807004290	ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590
1034807004291	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1034807004292	ATP binding site [chemical binding]; other site
1034807004293	Mg++ binding site [ion binding]; other site
1034807004294	motif III; other site
1034807004295	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1034807004296	nucleotide binding region [chemical binding]; other site
1034807004297	ATP-binding site [chemical binding]; other site
1034807004298	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1034807004299	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1034807004300	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1034807004301	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
1034807004302	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
1034807004303	WGR domain of molybdate metabolism regulator and related proteins; Region: WGR_MMR_like; cd07996
1034807004304	SWIM zinc finger; Region: SWIM; pfam04434
1034807004305	Protein of unknown function (DUF983); Region: DUF983; cl02211
1034807004306	A subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual...; Region: Band_7_5; cd03408
1034807004307	Short C-terminal domain; Region: SHOCT; pfam09851
1034807004308	Leucyl aminopeptidase [Amino acid transport and metabolism]; Region: PepB; COG0260
1034807004309	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1034807004310	interface (dimer of trimers) [polypeptide binding]; other site
1034807004311	Substrate-binding/catalytic site; other site
1034807004312	Zn-binding sites [ion binding]; other site
1034807004313	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1034807004314	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1034807004315	RNA binding surface [nucleotide binding]; other site
1034807004316	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1034807004317	active site
1034807004318	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1034807004319	PASTA domain; Region: PASTA; pfam03793
1034807004320	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
1034807004321	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1034807004322	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1034807004323	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
1034807004324	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1034807004325	active site
1034807004326	(T/H)XGH motif; other site
1034807004327	Superfamily II DNA helicase [DNA replication, recombination, and repair]; Region: RecQ; COG0514
1034807004328	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1034807004329	ATP binding site [chemical binding]; other site
1034807004330	putative Mg++ binding site [ion binding]; other site
1034807004331	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1034807004332	nucleotide binding region [chemical binding]; other site
1034807004333	ATP-binding site [chemical binding]; other site
1034807004334	RQC domain; Region: RQC; pfam09382
1034807004335	HRDC domain; Region: HRDC; pfam00570
1034807004336	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539
1034807004337	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1034807004338	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
1034807004339	NAD(P) binding site [chemical binding]; other site
1034807004340	homotetramer interface [polypeptide binding]; other site
1034807004341	homodimer interface [polypeptide binding]; other site
1034807004342	active site
1034807004343	WYL domain; Region: WYL; pfam13280
1034807004344	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
1034807004345	RT_Bac_retron_II: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_II; cd03487
1034807004346	putative active site [active]
1034807004347	putative NTP binding site [chemical binding]; other site
1034807004348	putative nucleic acid binding site [nucleotide binding]; other site
1034807004349	Superfamily II DNA helicase [DNA replication, recombination, and repair]; Region: RecQ; COG0514
1034807004350	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1034807004351	ATP binding site [chemical binding]; other site
1034807004352	putative Mg++ binding site [ion binding]; other site
1034807004353	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1034807004354	nucleotide binding region [chemical binding]; other site
1034807004355	ATP-binding site [chemical binding]; other site
1034807004356	AAA domain; Region: AAA_30; pfam13604
1034807004357	Family description; Region: UvrD_C_2; pfam13538
1034807004358	Zn-dependent oligopeptidases [Amino acid transport and metabolism]; Region: Dcp; COG0339
1034807004359	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1034807004360	active site
1034807004361	Zn binding site [ion binding]; other site
1034807004362	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
1034807004363	glyceraldehyde-3-phosphate dehydrogenase; Provisional; Region: PTZ00023
1034807004364	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1034807004365	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1034807004366	6-phosphofructokinase; Provisional; Region: PRK03202
1034807004367	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
1034807004368	active site
1034807004369	ADP/pyrophosphate binding site [chemical binding]; other site
1034807004370	dimerization interface [polypeptide binding]; other site
1034807004371	allosteric effector site; other site
1034807004372	fructose-1,6-bisphosphate binding site; other site
1034807004373	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1034807004374	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034807004375	S-adenosylmethionine binding site [chemical binding]; other site
1034807004376	Protein of unknown function (DUF1648); Region: DUF1648; pfam07853
1034807004377	Cellular and retroviral pepsin-like aspartate proteases; Region: pepsin_retropepsin_like; cl11403
1034807004378	inhibitor binding site; inhibition site
1034807004379	catalytic motif [active]
1034807004380	Catalytic residue [active]
1034807004381	Active site flap [active]
1034807004382	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1034807004383	Uncharacterized conserved protein [Function unknown]; Region: COG1479
1034807004384	Protein of unknown function DUF262; Region: DUF262; pfam03235
1034807004385	Protein of unknown function DUF262; Region: DUF262; pfam03235
1034807004386	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
1034807004387	active site
1034807004388	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1034807004389	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
1034807004390	active site
1034807004391	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1034807004392	peptidyl-prolyl isomerase, gliding motility-associated; Region: ppisom_GldI; TIGR03516
1034807004393	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1034807004394	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
1034807004395	DHH family; Region: DHH; pfam01368
1034807004396	DHHA1 domain; Region: DHHA1; pfam02272
1034807004397	Thiamine pyrophosphokinase; Region: TPK; cd07995
1034807004398	thiamine pyrophosphokinase; Region: thi_PPkinase; TIGR01378
1034807004399	active site
1034807004400	dimerization interface [polypeptide binding]; other site
1034807004401	thiamine binding site [chemical binding]; other site
1034807004402	Domain of unknown function (DUF4249); Region: DUF4249; pfam14054
1034807004403	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1034807004404	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1034807004405	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1034807004406	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
1034807004407	active site
1034807004408	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
1034807004409	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1034807004410	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
1034807004411	Clp amino terminal domain; Region: Clp_N; pfam02861
1034807004412	Clp amino terminal domain; Region: Clp_N; pfam02861
1034807004413	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034807004414	Walker A motif; other site
1034807004415	ATP binding site [chemical binding]; other site
1034807004416	Walker B motif; other site
1034807004417	arginine finger; other site
1034807004418	UvrB/uvrC motif; Region: UVR; pfam02151
1034807004419	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034807004420	Walker A motif; other site
1034807004421	ATP binding site [chemical binding]; other site
1034807004422	Walker B motif; other site
1034807004423	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1034807004424	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1034807004425	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1034807004426	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
1034807004427	M28 Zn-Peptidases containing a PA domain insert and associated with a PDZ domain; Region: M28_like_PA_PDZ_associated; cd05663
1034807004428	Peptidase family M28; Region: Peptidase_M28; pfam04389
1034807004429	metal binding site [ion binding]; metal-binding site
1034807004430	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
1034807004431	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1034807004432	DinB superfamily; Region: DinB_2; pfam12867
1034807004433	Uncharacterized protein conserved in bacteria (DUF2200); Region: DUF2200; pfam09966
1034807004434	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
1034807004435	active sites [active]
1034807004436	tetramer interface [polypeptide binding]; other site
1034807004437	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
1034807004438	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
1034807004439	putative catalytic residues [active]
1034807004440	putative nucleotide binding site [chemical binding]; other site
1034807004441	putative aspartate binding site [chemical binding]; other site
1034807004442	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
1034807004443	dimer interface [polypeptide binding]; other site
1034807004444	putative threonine allosteric regulatory site; other site
1034807004445	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
1034807004446	putative threonine allosteric regulatory site; other site
1034807004447	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1034807004448	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1034807004449	homoserine kinase; Provisional; Region: PRK01212
1034807004450	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1034807004451	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1034807004452	threonine synthase; Validated; Region: PRK09225
1034807004453	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
1034807004454	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1034807004455	catalytic residue [active]
1034807004456	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
1034807004457	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
1034807004458	hypothetical protein; Provisional; Region: PRK12378
1034807004459	GSCFA family; Region: GSCFA; pfam08885
1034807004460	Proline dehydrogenase; Region: Pro_dh; cl03282
1034807004461	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1034807004462	Homeodomain-like domain; Region: HTH_23; pfam13384
1034807004463	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034807004464	putative substrate translocation pore; other site
1034807004465	Na+/proline symporter [Amino acid transport and metabolism / General function prediction only]; Region: PutP; COG0591
1034807004466	Na binding site [ion binding]; other site
1034807004467	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1034807004468	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034807004469	dimer interface [polypeptide binding]; other site
1034807004470	phosphorylation site [posttranslational modification]
1034807004471	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034807004472	ATP binding site [chemical binding]; other site
1034807004473	Mg2+ binding site [ion binding]; other site
1034807004474	G-X-G motif; other site
1034807004475	Response regulator receiver domain; Region: Response_reg; pfam00072
1034807004476	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034807004477	active site
1034807004478	phosphorylation site [posttranslational modification]
1034807004479	intermolecular recognition site; other site
1034807004480	dimerization interface [polypeptide binding]; other site
1034807004481	propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524
1034807004482	Propionyl-CoA synthetase (PrpE); Region: PrpE; cd05967
1034807004483	acyl-activating enzyme (AAE) consensus motif; other site
1034807004484	putative AMP binding site [chemical binding]; other site
1034807004485	putative active site [active]
1034807004486	putative CoA binding site [chemical binding]; other site
1034807004487	acetyl-CoA synthetase; Provisional; Region: PRK00174
1034807004488	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
1034807004489	active site
1034807004490	CoA binding site [chemical binding]; other site
1034807004491	acyl-activating enzyme (AAE) consensus motif; other site
1034807004492	AMP binding site [chemical binding]; other site
1034807004493	acetate binding site [chemical binding]; other site
1034807004494	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
1034807004495	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
1034807004496	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1034807004497	ATP binding site [chemical binding]; other site
1034807004498	putative Mg++ binding site [ion binding]; other site
1034807004499	Uncharacterized conserved protein [Function unknown]; Region: COG1479
1034807004500	Protein of unknown function DUF262; Region: DUF262; pfam03235
1034807004501	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
1034807004502	Uncharacterized conserved protein [Function unknown]; Region: COG1479
1034807004503	Protein of unknown function DUF262; Region: DUF262; pfam03235
1034807004504	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1034807004505	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1034807004506	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1034807004507	ORF6N domain; Region: ORF6N; pfam10543
1034807004508	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
1034807004509	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
1034807004510	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1034807004511	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034807004512	S-adenosylmethionine binding site [chemical binding]; other site
1034807004513	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09311
1034807004514	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
1034807004515	GTP cyclohydrolase II; Region: GTP_cyclohydro2; pfam00925
1034807004516	dimerization interface [polypeptide binding]; other site
1034807004517	active site
1034807004518	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
1034807004519	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1034807004520	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1034807004521	Predicted permeases [General function prediction only]; Region: COG0795; cl12074
1034807004522	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
1034807004523	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
1034807004524	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
1034807004525	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1034807004526	This domain directs oriented DNA translocation and forms a winged helix structure; Region: Ftsk_gamma; smart00843
1034807004527	Prokaryotic diacylglycerol kinase; Region: DAGK_prokar; pfam01219
1034807004528	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
1034807004529	dimer interface [polypeptide binding]; other site
1034807004530	catalytic triad [active]
1034807004531	peroxidatic and resolving cysteines [active]
1034807004532	RNA polymerase sigma factor; Provisional; Region: PRK12513
1034807004533	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1034807004534	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1034807004535	DNA binding residues [nucleotide binding]
1034807004536	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
1034807004537	SPFH domain / Band 7 family; Region: Band_7; pfam01145
1034807004538	Histidine kinase; Region: His_kinase; pfam06580
1034807004539	2TM domain; Region: 2TM; pfam13239
1034807004540	2TM domain; Region: 2TM; pfam13239
1034807004541	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1034807004542	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034807004543	active site
1034807004544	phosphorylation site [posttranslational modification]
1034807004545	intermolecular recognition site; other site
1034807004546	dimerization interface [polypeptide binding]; other site
1034807004547	LytTr DNA-binding domain; Region: LytTR; smart00850
1034807004548	Glycogen debranching enzyme [Carbohydrate transport and metabolism]; Region: GDB1; COG3408
1034807004549	Protein of unknown function, DUF608; Region: DUF608; pfam04685
1034807004550	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1034807004551	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
1034807004552	nudix motif; other site
1034807004553	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
1034807004554	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1034807004555	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1034807004556	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1034807004557	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
1034807004558	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1034807004559	generic binding surface II; other site
1034807004560	ssDNA binding site; other site
1034807004561	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1034807004562	ATP binding site [chemical binding]; other site
1034807004563	putative Mg++ binding site [ion binding]; other site
1034807004564	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1034807004565	nucleotide binding region [chemical binding]; other site
1034807004566	ATP-binding site [chemical binding]; other site
1034807004567	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1034807004568	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
1034807004569	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1034807004570	trimer interface [polypeptide binding]; other site
1034807004571	active site
1034807004572	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1034807004573	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1034807004574	active site
1034807004575	HIGH motif; other site
1034807004576	dimer interface [polypeptide binding]; other site
1034807004577	KMSKS motif; other site
1034807004578	nucleoside transporter; Region: 2A0110; TIGR00889
1034807004579	cytidylate kinase; Provisional; Region: cmk; PRK00023
1034807004580	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
1034807004581	CMP-binding site; other site
1034807004582	The sites determining sugar specificity; other site
1034807004583	malate dehydrogenase; Reviewed; Region: PRK06223
1034807004584	L-lactate dehydrogenase-like malate dehydrogenase proteins; Region: LDH-like_MDH; cd01339
1034807004585	NAD(P) binding site [chemical binding]; other site
1034807004586	dimer interface [polypeptide binding]; other site
1034807004587	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1034807004588	substrate binding site [chemical binding]; other site
1034807004589	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
1034807004590	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1034807004591	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
1034807004592	Protein export membrane protein; Region: SecD_SecF; pfam02355
1034807004593	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1034807004594	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
1034807004595	nucleotide binding site [chemical binding]; other site
1034807004596	NEF interaction site [polypeptide binding]; other site
1034807004597	SBD interface [polypeptide binding]; other site
1034807004598	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1034807004599	Domain of unknown function (DUF4136); Region: DUF4136; pfam13590
1034807004600	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
1034807004601	tRNA-binding-domain-containing CsaA-like proteins. CsaA is a molecular chaperone with export related activities. CsaA has a putative tRNA binding activity. The functional unit of CsaA is a homodimer and this domain acts as a dimerization domain; Region: tRNA_bind_CsaA; cd02798
1034807004602	dimer interface [polypeptide binding]; other site
1034807004603	putative tRNA-binding site [nucleotide binding]; other site
1034807004604	Protein of unknown function (DUF3276); Region: DUF3276; pfam11680
1034807004605	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1034807004606	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1034807004607	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034807004608	Walker A/P-loop; other site
1034807004609	ATP binding site [chemical binding]; other site
1034807004610	Q-loop/lid; other site
1034807004611	ABC transporter signature motif; other site
1034807004612	Walker B; other site
1034807004613	D-loop; other site
1034807004614	H-loop/switch region; other site
1034807004615	transcription antitermination factor NusB; Region: nusB; TIGR01951
1034807004616	Preprotein translocase subunit; Region: YajC; pfam02699
1034807004617	Uncharacterized protein conserved in archaea [Posttranslational modification, protein turnover, chaperones]; Region: COG4067
1034807004618	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
1034807004619	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1034807004620	Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism / Amino acid transport and metabolism]; Region: PrsA; COG0462
1034807004621	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1034807004622	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1034807004623	active site
1034807004624	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_3; pfam13366
1034807004625	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
1034807004626	putative active site [active]
1034807004627	putative ADP-ribose binding site [chemical binding]; other site
1034807004628	ADP-ribosylglycohydrolase; Region: ADP_ribosyl_GH; pfam03747
1034807004629	Domain of unknown function (DUF1768); Region: DUF1768; pfam08719
1034807004630	RNA 2'-phosphotransferase; Reviewed; Region: PRK00819
1034807004631	RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; Region: KptA; COG1859
1034807004632	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1034807004633	phosphoprotein phosphatases of the metallophosphatase superfamily, metallophosphatase domain; Region: MPP_PPP_family; cd00144
1034807004634	active site
1034807004635	metal binding site [ion binding]; metal-binding site
1034807004636	putative nicotinate phosphoribosyltransferase; Provisional; Region: PRK09198
1034807004637	pre-B-cell colony-enhancing factor (PBEF)-like. The mammalian members of this group of nicotinate phosphoribosyltransferases (NAPRTases) were originally identified as genes whose expression is upregulated upon activation in lymphoid cells. In general; Region: PBEF_like; cd01569
1034807004638	active site
1034807004639	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1034807004640	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034807004641	active site
1034807004642	phosphorylation site [posttranslational modification]
1034807004643	intermolecular recognition site; other site
1034807004644	dimerization interface [polypeptide binding]; other site
1034807004645	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1034807004646	DNA binding site [nucleotide binding]
1034807004647	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1034807004648	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034807004649	dimer interface [polypeptide binding]; other site
1034807004650	phosphorylation site [posttranslational modification]
1034807004651	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034807004652	ATP binding site [chemical binding]; other site
1034807004653	Mg2+ binding site [ion binding]; other site
1034807004654	G-X-G motif; other site
1034807004655	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1034807004656	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1034807004657	CoA-binding site [chemical binding]; other site
1034807004658	ATP-binding [chemical binding]; other site
1034807004659	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
1034807004660	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1034807004661	active site
1034807004662	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807004663	trans-2-enoyl-CoA reductase; Provisional; Region: PRK13656
1034807004664	NAD(P)H binding domain of trans-2-enoyl-CoA reductase; Region: Eno-Rase_NADH_b; pfam12242
1034807004665	Trans-2-enoyl-CoA reductase catalytic region; Region: Enoyl_reductase; pfam12241
1034807004666	Enoyl reductase FAD binding domain; Region: Eno-Rase_FAD_bd; pfam07055
1034807004667	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
1034807004668	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1034807004669	Walker A/P-loop; other site
1034807004670	ATP binding site [chemical binding]; other site
1034807004671	Q-loop/lid; other site
1034807004672	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1034807004673	ABC transporter signature motif; other site
1034807004674	Walker B; other site
1034807004675	D-loop; other site
1034807004676	H-loop/switch region; other site
1034807004677	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
1034807004678	Flavoprotein; Region: Flavoprotein; pfam02441
1034807004679	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
1034807004680	RNA polymerase Rpb6; Region: RNA_pol_Rpb6; cl14651
1034807004681	outer membrane assembly lipoprotein YfiO; Region: OM_YfiO; TIGR03302
1034807004682	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1034807004683	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1034807004684	dimer interface [polypeptide binding]; other site
1034807004685	active site
1034807004686	catalytic residue [active]
1034807004687	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1034807004688	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
1034807004689	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1034807004690	active site
1034807004691	metal binding site [ion binding]; metal-binding site
1034807004692	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1034807004693	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1034807004694	nucleotide binding pocket [chemical binding]; other site
1034807004695	K-X-D-G motif; other site
1034807004696	catalytic site [active]
1034807004697	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1034807004698	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
1034807004699	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1034807004700	Dimer interface [polypeptide binding]; other site
1034807004701	BRCT sequence motif; other site
1034807004702	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1034807004703	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1034807004704	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1034807004705	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1034807004706	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1034807004707	FRG domain; Region: FRG; pfam08867
1034807004708	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
1034807004709	cyclase homology domain; Region: CHD; cd07302
1034807004710	nucleotidyl binding site; other site
1034807004711	metal binding site [ion binding]; metal-binding site
1034807004712	dimer interface [polypeptide binding]; other site
1034807004713	Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism]; Region: TrpE; COG0147
1034807004714	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1034807004715	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1034807004716	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1034807004717	Glutamine amidotransferase class-I; Region: GATase; pfam00117
1034807004718	glutamine binding [chemical binding]; other site
1034807004719	catalytic triad [active]
1034807004720	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
1034807004721	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1034807004722	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1034807004723	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
1034807004724	active site
1034807004725	ribulose/triose binding site [chemical binding]; other site
1034807004726	phosphate binding site [ion binding]; other site
1034807004727	substrate (anthranilate) binding pocket [chemical binding]; other site
1034807004728	product (indole) binding pocket [chemical binding]; other site
1034807004729	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
1034807004730	active site
1034807004731	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
1034807004732	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1034807004733	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034807004734	catalytic residue [active]
1034807004735	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
1034807004736	putative active site pocket [active]
1034807004737	dimerization interface [polypeptide binding]; other site
1034807004738	putative catalytic residue [active]
1034807004739	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
1034807004740	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
1034807004741	substrate binding site [chemical binding]; other site
1034807004742	active site
1034807004743	catalytic residues [active]
1034807004744	heterodimer interface [polypeptide binding]; other site
1034807004745	Protein of unknown function (DUF2752); Region: DUF2752; pfam10825
1034807004746	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
1034807004747	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1034807004748	dimerization interface 3.5A [polypeptide binding]; other site
1034807004749	active site
1034807004750	Plasmid pRiA4b ORF-3-like protein; Region: PRiA4_ORF3; pfam07929
1034807004751	37-kD nucleoid-associated bacterial protein; Region: NA37; pfam04245
1034807004752	aspartate aminotransferase; Provisional; Region: PRK07568
1034807004753	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1034807004754	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034807004755	homodimer interface [polypeptide binding]; other site
1034807004756	catalytic residue [active]
1034807004757	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1034807004758	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cl02915
1034807004759	Cl- selectivity filter; other site
1034807004760	Cl- binding residues [ion binding]; other site
1034807004761	pore gating glutamate residue; other site
1034807004762	dimer interface [polypeptide binding]; other site
1034807004763	Predicted Fe-S oxidoreductases [General function prediction only]; Region: COG1964
1034807004764	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1034807004765	FeS/SAM binding site; other site
1034807004766	Uncharacterized conserved protein (DUF2132); Region: DUF2132; pfam09905
1034807004767	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1034807004768	SmpB-tmRNA interface; other site
1034807004769	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034807004770	non-specific DNA binding site [nucleotide binding]; other site
1034807004771	salt bridge; other site
1034807004772	sequence-specific DNA binding site [nucleotide binding]; other site
1034807004773	Fic family protein [Function unknown]; Region: COG3177
1034807004774	Fic/DOC family; Region: Fic; pfam02661
1034807004775	Protein-L-isoaspartate carboxylmethyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: Pcm; COG2518
1034807004776	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034807004777	S-adenosylmethionine binding site [chemical binding]; other site
1034807004778	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1034807004779	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1034807004780	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1034807004781	3-hydroxybutyryl-CoA dehydrogenase; Validated; Region: PRK05808
1034807004782	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1034807004783	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
1034807004784	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
1034807004785	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1034807004786	catalytic residue [active]
1034807004787	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1034807004788	active site
1034807004789	catalytic site [active]
1034807004790	substrate binding site [chemical binding]; other site
1034807004791	nucleotide excision repair endonuclease; Provisional; Region: PRK10545
1034807004792	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1034807004793	GIY-YIG motif/motif A; other site
1034807004794	active site
1034807004795	catalytic site [active]
1034807004796	putative DNA binding site [nucleotide binding]; other site
1034807004797	metal binding site [ion binding]; metal-binding site
1034807004798	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1034807004799	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1034807004800	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1034807004801	active site
1034807004802	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
1034807004803	active site 2 [active]
1034807004804	active site 1 [active]
1034807004805	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
1034807004806	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034807004807	motif II; other site
1034807004808	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
1034807004809	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
1034807004810	Walker A/P-loop; other site
1034807004811	ATP binding site [chemical binding]; other site
1034807004812	Q-loop/lid; other site
1034807004813	ABC transporter signature motif; other site
1034807004814	Walker B; other site
1034807004815	D-loop; other site
1034807004816	H-loop/switch region; other site
1034807004817	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
1034807004818	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
1034807004819	KpsF/GutQ family protein; Region: kpsF; TIGR00393
1034807004820	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1034807004821	putative active site [active]
1034807004822	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1034807004823	ATP-dependent DNA helicase RecQ; Region: recQ; TIGR01389
1034807004824	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1034807004825	ATP binding site [chemical binding]; other site
1034807004826	putative Mg++ binding site [ion binding]; other site
1034807004827	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1034807004828	nucleotide binding region [chemical binding]; other site
1034807004829	ATP-binding site [chemical binding]; other site
1034807004830	RQC domain; Region: RQC; pfam09382
1034807004831	HRDC domain; Region: HRDC; pfam00570
1034807004832	YegX is an uncharacterized bacterial protein with a glycosyl hydrolase family 25 (GH25) catalytic domain that is similar in sequence to the CH-type (Chalaropsis-type) lysozymes of the GH25 family of endolysins; Region: GH25_YegX-like; cd06524
1034807004833	Glycosyl hydrolases family 25; Region: Glyco_hydro_25; pfam01183
1034807004834	active site
1034807004835	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
1034807004836	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
1034807004837	Domain of unknown function (DUF4105); Region: DUF4105; pfam13387
1034807004838	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
1034807004839	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1034807004840	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1034807004841	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1034807004842	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
1034807004843	putative ADP-binding pocket [chemical binding]; other site
1034807004844	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1034807004845	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1034807004846	Glycosyl transferases group 1; Region: Glycos_transf_1; pfam00534
1034807004847	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
1034807004848	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1034807004849	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1034807004850	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1034807004851	gliding motility associated protien GldN; Region: GldN; TIGR03523
1034807004852	gliding motility-associated protein GldM; Region: GldM_gliding; TIGR03517
1034807004853	GldM N-terminal domain; Region: GldM_N; pfam12081
1034807004854	GldM C-terminal domain; Region: GldM_C; pfam12080
1034807004855	gliding motility-associated protein GldL; Region: GldL_gliding; TIGR03513
1034807004856	gliding motility-associated lipoprotein GldK; Region: GldK; TIGR03525
1034807004857	gliding motility-associated lipoprotein GldJ; Region: GldJ; TIGR03524
1034807004858	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
1034807004859	Formimidoylglutamase or HutE; Region: Formimidoylglutamase; cd09988
1034807004860	putative active site [active]
1034807004861	putative metal binding site [ion binding]; other site
1034807004862	DNA topoisomerase I; Validated; Region: PRK06599
1034807004863	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1034807004864	active site
1034807004865	interdomain interaction site; other site
1034807004866	putative metal-binding site [ion binding]; other site
1034807004867	nucleotide binding site [chemical binding]; other site
1034807004868	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1034807004869	domain I; other site
1034807004870	DNA binding groove [nucleotide binding]
1034807004871	phosphate binding site [ion binding]; other site
1034807004872	domain II; other site
1034807004873	domain III; other site
1034807004874	nucleotide binding site [chemical binding]; other site
1034807004875	catalytic site [active]
1034807004876	domain IV; other site
1034807004877	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
1034807004878	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
1034807004879	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14329
1034807004880	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1034807004881	TRAM domain; Region: TRAM; pfam01938
1034807004882	ApaLI-like restriction endonuclease; Region: RE_ApaLI; pfam09499
1034807004883	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034807004884	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1034807004885	Walker A motif; other site
1034807004886	ATP binding site [chemical binding]; other site
1034807004887	Walker B motif; other site
1034807004888	arginine finger; other site
1034807004889	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
1034807004890	Lipopolysaccharide-assembly; Region: LptE; pfam04390
1034807004891	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1034807004892	oligomerisation interface [polypeptide binding]; other site
1034807004893	mobile loop; other site
1034807004894	roof hairpin; other site
1034807004895	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1034807004896	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1034807004897	ring oligomerisation interface [polypeptide binding]; other site
1034807004898	ATP/Mg binding site [chemical binding]; other site
1034807004899	stacking interactions; other site
1034807004900	hinge regions; other site
1034807004901	Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116
1034807004902	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
1034807004903	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1034807004904	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034807004905	S-adenosylmethionine binding site [chemical binding]; other site
1034807004906	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
1034807004907	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
1034807004908	putative active site [active]
1034807004909	Vacuole effluxer Atg22 like; Region: ATG22; pfam11700
1034807004910	Sulfatase; Region: Sulfatase; pfam00884
1034807004911	Thioredoxin-like domain; Region: Thioredoxin_2; pfam13098
1034807004912	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
1034807004913	ApbE family; Region: ApbE; pfam02424
1034807004914	Domain of unknown function (DUF4266); Region: DUF4266; pfam14086
1034807004915	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1034807004916	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034807004917	active site
1034807004918	phosphorylation site [posttranslational modification]
1034807004919	intermolecular recognition site; other site
1034807004920	dimerization interface [polypeptide binding]; other site
1034807004921	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1034807004922	DNA binding site [nucleotide binding]
1034807004923	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
1034807004924	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304
1034807004925	dimerization interface [polypeptide binding]; other site
1034807004926	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034807004927	dimer interface [polypeptide binding]; other site
1034807004928	phosphorylation site [posttranslational modification]
1034807004929	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034807004930	ATP binding site [chemical binding]; other site
1034807004931	Mg2+ binding site [ion binding]; other site
1034807004932	G-X-G motif; other site
1034807004933	Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and...; Region: LbH_XAT; cd03349
1034807004934	trimer interface [polypeptide binding]; other site
1034807004935	active site
1034807004936	substrate binding site [chemical binding]; other site
1034807004937	CoA binding site [chemical binding]; other site
1034807004938	type I restriction system adenine methylase (hsdM); Region: hsdM; TIGR00497
1034807004939	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1034807004940	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1034807004941	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1034807004942	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1034807004943	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1034807004944	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1034807004945	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1034807004946	Uncharacterized conserved protein [Function unknown]; Region: COG4127
1034807004947	Staphylococcal nuclease homologues. SNase homologues are found in bacteria, archaea, and eukaryotes. They contain no disufide bonds; Region: SNc; cl00140
1034807004948	Catalytic site; other site
1034807004949	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807004950	glutamate synthase subunit beta; Reviewed; Region: gltD; PRK12810
1034807004951	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
1034807004952	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1034807004953	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
1034807004954	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
1034807004955	active site
1034807004956	dimer interface [polypeptide binding]; other site
1034807004957	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
1034807004958	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
1034807004959	active site
1034807004960	FMN binding site [chemical binding]; other site
1034807004961	substrate binding site [chemical binding]; other site
1034807004962	3Fe-4S cluster binding site [ion binding]; other site
1034807004963	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
1034807004964	domain interface; other site
1034807004965	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
1034807004966	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
1034807004967	CoA-ligase; Region: Ligase_CoA; pfam00549
1034807004968	YceI-like domain; Region: YceI; pfam04264
1034807004969	tRNA_anti-like; Region: tRNA_anti-like; pfam12869
1034807004970	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807004971	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1034807004972	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1034807004973	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1034807004974	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1034807004975	Walker A/P-loop; other site
1034807004976	ATP binding site [chemical binding]; other site
1034807004977	Q-loop/lid; other site
1034807004978	ABC transporter signature motif; other site
1034807004979	Walker B; other site
1034807004980	D-loop; other site
1034807004981	H-loop/switch region; other site
1034807004982	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
1034807004983	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1034807004984	FtsX-like permease family; Region: FtsX; pfam02687
1034807004985	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1034807004986	HlyD family secretion protein; Region: HlyD_3; pfam13437
1034807004987	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1034807004988	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1034807004989	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1034807004990	YsiA-like protein, C-terminal region; Region: TetR_C_4; pfam08359
1034807004991	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807004992	Archaebacterial flagellin; Region: Arch_flagellin; cl00732
1034807004993	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1034807004994	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1034807004995	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034807004996	non-specific DNA binding site [nucleotide binding]; other site
1034807004997	salt bridge; other site
1034807004998	sequence-specific DNA binding site [nucleotide binding]; other site
1034807004999	Plasmid encoded toxin Txe; Region: Plasmid_Txe; cl17389
1034807005000	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
1034807005001	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807005002	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1034807005003	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
1034807005004	hydrophobic ligand binding site; other site
1034807005005	Na(+)/iodide (NIS) and Na(+)/multivitamin (SMVT) cotransporters, and related proteins; solute binding domain; Region: SLC5sbd_NIS-like; cd10326
1034807005006	Na binding site [ion binding]; other site
1034807005007	Cytochrome oxidase maturation protein cbb3-type; Region: CcoS; pfam03597
1034807005008	putative bifunctional cbb3-type cytochrome c oxidase subunit I/II; Provisional; Region: PRK14485
1034807005009	Cytochrome cbb3 oxidase subunit I.  Cytochrome cbb3 oxidase, the terminal oxidase in the respiratory chains of proteobacteria, is a multi-chain transmembrane protein located in the cell membrane. Like other cytochrome oxidases, it catalyzes the reduction...; Region: cbb3_Oxidase_I; cd01661
1034807005010	Low-spin heme binding site [chemical binding]; other site
1034807005011	Putative water exit pathway; other site
1034807005012	Binuclear center (active site) [active]
1034807005013	Putative proton exit pathway; other site
1034807005014	Cytochrome C oxidase, mono-heme subunit/FixO; Region: FixO; pfam02433
1034807005015	Cytochrome cbb oxidase CcoQ.  Cytochrome cbb3 oxidase, the terminal oxidase in the respiratory chains of proteobacteria, is a multi-chain transmembrane protein located in the cell membrane. Like other cytochrome oxidases, it catalyzes the reduction of O2...; Region: cbb3_Oxidase_CcoQ; cl00282
1034807005016	cytochrome c oxidase, cbb3-type, subunit III; Region: ccoP; TIGR00782
1034807005017	Cytochrome c; Region: Cytochrom_C; pfam00034
1034807005018	cytochrome c oxidase accessory protein FixG; Region: ccoG_rdxA_fixG; TIGR02745
1034807005019	4Fe-4S binding domain; Region: Fer4_5; pfam12801
1034807005020	4Fe-4S binding domain; Region: Fer4; pfam00037
1034807005021	Ubp3 associated protein Bre5; Region: Bre5; pfam11614
1034807005022	FixH; Region: FixH; pfam05751
1034807005023	Family description; Region: DsbD_2; pfam13386
1034807005024	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
1034807005025	Protein of unknown function (DUF2490); Region: DUF2490; pfam10677
1034807005026	Sulphur transport; Region: Sulf_transp; pfam04143
1034807005027	Domain of unknown function (DUF4341); Region: DUF4341; pfam14241
1034807005028	Predicted transporter component [General function prediction only]; Region: COG2391
1034807005029	Sulphur transport; Region: Sulf_transp; pfam04143
1034807005030	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1034807005031	GLPGLI family protein; Region: GLPGLI; TIGR01200
1034807005032	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
1034807005033	CarD-like/TRCF domain; Region: CarD_CdnL_TRCF; pfam02559
1034807005034	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1034807005035	ATP binding site [chemical binding]; other site
1034807005036	putative Mg++ binding site [ion binding]; other site
1034807005037	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1034807005038	nucleotide binding region [chemical binding]; other site
1034807005039	ATP-binding site [chemical binding]; other site
1034807005040	TRCF domain; Region: TRCF; pfam03461
1034807005041	Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only]; Region: COG2329
1034807005042	M28 Zn-peptidase Endoplasmic reticulum metallopeptidase 1; Region: M28_Fxna_like; cd03875
1034807005043	Peptidase family M28; Region: Peptidase_M28; pfam04389
1034807005044	metal binding site [ion binding]; metal-binding site
1034807005045	Domain of unknown function (DUF329); Region: DUF329; cl01144
1034807005046	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1034807005047	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1034807005048	dimer interface [polypeptide binding]; other site
1034807005049	ssDNA binding site [nucleotide binding]; other site
1034807005050	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1034807005051	gliding motility-associated C-terminal domain; Region: Bac_Flav_CTERM; TIGR04131
1034807005052	Cobalamin adenosyltransferase; Region: Cob_adeno_trans; pfam01923
1034807005053	Protein of unknown function (DUF2795); Region: DUF2795; pfam11387
1034807005054	preprotein translocase subunit SecA; Reviewed; Region: secA; PRK12901
1034807005055	SecA preprotein cross-linking domain; Region: SecA_PP_bind; pfam01043
1034807005056	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1034807005057	nucleotide binding region [chemical binding]; other site
1034807005058	ATP-binding site [chemical binding]; other site
1034807005059	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; smart00782
1034807005060	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
1034807005061	PhnA protein; Region: PhnA; pfam03831
1034807005062	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1034807005063	Putative esterase; Region: Esterase; pfam00756
1034807005064	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4947
1034807005065	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
1034807005066	Transposase IS200 like; Region: Y1_Tnp; cl00848
1034807005067	Transposase IS200 like; Region: Y1_Tnp; cl00848
1034807005068	methylmalonyl CoA mutase B12 binding domain. This domain binds to B12 (adenosylcobamide), which initiates the conversion of succinyl CoA and methylmalonyl CoA by forming an adenosyl radical, which then undergoes a rearrangement exchanging a hydrogen atom...; Region: MM_CoA_mut_B12_BD; cd02071
1034807005069	B12 binding site [chemical binding]; other site
1034807005070	cobalt ligand [ion binding]; other site
1034807005071	Putative periplasmic protein kinase ArgK and related GTPases of G3E family [Amino acid transport and metabolism]; Region: ArgK; COG1703
1034807005072	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1034807005073	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM)-like family; contains proteins similar to MCM, and the large subunit of Streptomyces coenzyme B12-dependent isobutyryl-CoA mutase (ICM). MCM catalyzes the isomerization of...; Region: MM_CoA_mutase; cl00817
1034807005074	Uncharacterized protein conserved in bacteria (DUF2317); Region: DUF2317; pfam10079
1034807005075	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4365
1034807005076	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034807005077	dimer interface [polypeptide binding]; other site
1034807005078	phosphorylation site [posttranslational modification]
1034807005079	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034807005080	ATP binding site [chemical binding]; other site
1034807005081	Mg2+ binding site [ion binding]; other site
1034807005082	G-X-G motif; other site
1034807005083	Response regulator receiver domain; Region: Response_reg; pfam00072
1034807005084	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034807005085	active site
1034807005086	phosphorylation site [posttranslational modification]
1034807005087	intermolecular recognition site; other site
1034807005088	dimerization interface [polypeptide binding]; other site
1034807005089	fumarylacetoacetase; Region: PLN02856
1034807005090	Domain of unknown function (DUF1969); Region: DUF1969; pfam09298
1034807005091	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1034807005092	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
1034807005093	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1034807005094	dimer interface [polypeptide binding]; other site
1034807005095	active site
1034807005096	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1034807005097	folate binding site [chemical binding]; other site
1034807005098	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1034807005099	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034807005100	Coenzyme A binding pocket [chemical binding]; other site
1034807005101	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cl02931
1034807005102	ligand binding site [chemical binding]; other site
1034807005103	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1034807005104	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1034807005105	ligand binding site [chemical binding]; other site
1034807005106	Domain of unknown function (DUF4268); Region: DUF4268; pfam14088
1034807005107	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
1034807005108	PspC domain; Region: PspC; pfam04024
1034807005109	Predicted membrane protein [Function unknown]; Region: COG2259
1034807005110	Predicted transcriptional regulators [Transcription]; Region: COG1695
1034807005111	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1034807005112	putative Zn2+ binding site [ion binding]; other site
1034807005113	putative DNA binding site [nucleotide binding]; other site
1034807005114	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1034807005115	TIGR01777 family protein; Region: yfcH
1034807005116	NAD(P) binding site [chemical binding]; other site
1034807005117	active site
1034807005118	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034807005119	Coenzyme A binding pocket [chemical binding]; other site
1034807005120	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
1034807005121	Ligand Binding Site [chemical binding]; other site
1034807005122	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
1034807005123	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1034807005124	Ornithine/acetylornithine aminotransferase [Amino acid transport and metabolism]; Region: ArgD; COG4992
1034807005125	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1034807005126	inhibitor-cofactor binding pocket; inhibition site
1034807005127	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034807005128	catalytic residue [active]
1034807005129	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
1034807005130	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
1034807005131	putative catalytic cysteine [active]
1034807005132	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
1034807005133	nucleotide binding site [chemical binding]; other site
1034807005134	homotetrameric interface [polypeptide binding]; other site
1034807005135	putative phosphate binding site [ion binding]; other site
1034807005136	putative allosteric binding site; other site
1034807005137	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1034807005138	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1034807005139	AAK_NAGK-like: N-Acetyl-L-glutamate kinase (NAGK)-like . Included in this CD are the Escherichia coli and Pseudomonas aeruginosa type NAGKs which catalyze the phosphorylation of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine...; Region: AAK_NAGK-like; cd04238
1034807005140	nucleotide binding site [chemical binding]; other site
1034807005141	N-acetyl-L-glutamate binding site [chemical binding]; other site
1034807005142	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; Region: ArgE; COG0624
1034807005143	M20 Peptidases with similarity to acetylornithine deacetylases and succinyl-diaminopimelate desuccinylases; Region: M20_ArgE_DapE_like5; cd05651
1034807005144	metal binding site [ion binding]; metal-binding site
1034807005145	dimer interface [polypeptide binding]; other site
1034807005146	Lyase; Region: Lyase_1; pfam00206
1034807005147	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
1034807005148	active sites [active]
1034807005149	tetramer interface [polypeptide binding]; other site
1034807005150	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
1034807005151	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
1034807005152	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
1034807005153	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
1034807005154	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1034807005155	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1034807005156	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1034807005157	catalytic residue [active]
1034807005158	putative hydrolase; Provisional; Region: PRK11460
1034807005159	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1034807005160	Di-haem cytochrome c peroxidase; Region: CCP_MauG; pfam03150
1034807005161	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
1034807005162	CoA binding domain; Region: CoA_binding; smart00881
1034807005163	CoA-ligase; Region: Ligase_CoA; pfam00549
1034807005164	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
1034807005165	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1034807005166	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1034807005167	trimer interface [polypeptide binding]; other site
1034807005168	active site
1034807005169	UDP-GlcNAc binding site [chemical binding]; other site
1034807005170	lipid binding site [chemical binding]; lipid-binding site
1034807005171	elongation factor P; Validated; Region: PRK00529
1034807005172	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1034807005173	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1034807005174	RNA binding site [nucleotide binding]; other site
1034807005175	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1034807005176	RNA binding site [nucleotide binding]; other site
1034807005177	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
1034807005178	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
1034807005179	acyl-activating enzyme (AAE) consensus motif; other site
1034807005180	putative AMP binding site [chemical binding]; other site
1034807005181	putative active site [active]
1034807005182	putative CoA binding site [chemical binding]; other site
1034807005183	Protein of unknown function (DUF456); Region: DUF456; pfam04306
1034807005184	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1034807005185	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1034807005186	motif 1; other site
1034807005187	active site
1034807005188	motif 2; other site
1034807005189	motif 3; other site
1034807005190	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1034807005191	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1034807005192	Peptidase family M23; Region: Peptidase_M23; pfam01551
1034807005193	Helix-Turn-Helix DNA binding domain of putative MlrA-like transcription regulators; Region: HTH_MlrA-like_sg2; cd04765
1034807005194	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1034807005195	DNA binding residues [nucleotide binding]
1034807005196	LemA family; Region: LemA; cl00742
1034807005197	Repair protein; Region: Repair_PSII; pfam04536
1034807005198	Repair protein; Region: Repair_PSII; pfam04536
1034807005199	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1034807005200	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1034807005201	ligand binding site [chemical binding]; other site
1034807005202	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
1034807005203	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1034807005204	pseudouridine synthase; Region: TIGR00093
1034807005205	active site
1034807005206	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
1034807005207	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1034807005208	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
1034807005209	ATP-grasp domain; Region: ATP-grasp; pfam02222
1034807005210	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1034807005211	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1034807005212	exosortase F-associated protein; Region: flavo_near_exo; TIGR04127
1034807005213	Predicted membrane protein [Function unknown]; Region: COG4083; cl15694
1034807005214	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1034807005215	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
1034807005216	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1034807005217	active site
1034807005218	catalytic site [active]
1034807005219	substrate binding site [chemical binding]; other site
1034807005220	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1034807005221	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1034807005222	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cl00086
1034807005223	competence damage-inducible protein A; Provisional; Region: PRK00549
1034807005224	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
1034807005225	putative MPT binding site; other site
1034807005226	Competence-damaged protein; Region: CinA; pfam02464
1034807005227	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1034807005228	ribosomal protein L33; Region: rpl33; CHL00104
1034807005229	Domain of unknown function (DUF4295); Region: DUF4295; pfam14128
1034807005230	benzoate transport; Region: 2A0115; TIGR00895
1034807005231	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1034807005232	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1034807005233	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1034807005234	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1034807005235	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034807005236	dimer interface [polypeptide binding]; other site
1034807005237	phosphorylation site [posttranslational modification]
1034807005238	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034807005239	ATP binding site [chemical binding]; other site
1034807005240	Mg2+ binding site [ion binding]; other site
1034807005241	G-X-G motif; other site
1034807005242	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1034807005243	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034807005244	active site
1034807005245	phosphorylation site [posttranslational modification]
1034807005246	intermolecular recognition site; other site
1034807005247	dimerization interface [polypeptide binding]; other site
1034807005248	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1034807005249	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034807005250	dimer interface [polypeptide binding]; other site
1034807005251	phosphorylation site [posttranslational modification]
1034807005252	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034807005253	ATP binding site [chemical binding]; other site
1034807005254	Mg2+ binding site [ion binding]; other site
1034807005255	G-X-G motif; other site
1034807005256	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1034807005257	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034807005258	active site
1034807005259	phosphorylation site [posttranslational modification]
1034807005260	intermolecular recognition site; other site
1034807005261	dimerization interface [polypeptide binding]; other site
1034807005262	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1034807005263	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034807005264	dimer interface [polypeptide binding]; other site
1034807005265	phosphorylation site [posttranslational modification]
1034807005266	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034807005267	ATP binding site [chemical binding]; other site
1034807005268	Mg2+ binding site [ion binding]; other site
1034807005269	G-X-G motif; other site
1034807005270	Response regulator receiver domain; Region: Response_reg; pfam00072
1034807005271	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034807005272	active site
1034807005273	phosphorylation site [posttranslational modification]
1034807005274	intermolecular recognition site; other site
1034807005275	dimerization interface [polypeptide binding]; other site
1034807005276	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1034807005277	GTP-binding protein TypA/BipA; Region: TypA_BipA; TIGR01394
1034807005278	G1 box; other site
1034807005279	putative GEF interaction site [polypeptide binding]; other site
1034807005280	GTP/Mg2+ binding site [chemical binding]; other site
1034807005281	Switch I region; other site
1034807005282	G2 box; other site
1034807005283	G3 box; other site
1034807005284	Switch II region; other site
1034807005285	G4 box; other site
1034807005286	G5 box; other site
1034807005287	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1034807005288	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1034807005289	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1034807005290	prolyl-tRNA synthetase; Provisional; Region: PRK08661
1034807005291	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_arch_euk; cd00778
1034807005292	dimer interface [polypeptide binding]; other site
1034807005293	motif 1; other site
1034807005294	active site
1034807005295	motif 2; other site
1034807005296	motif 3; other site
1034807005297	ProRS Prolyl-anticodon binding domain, long version found predominantly in eukaryotes and archaea. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in...; Region: ProRS_anticodon_zinc; cd00862
1034807005298	anticodon binding site; other site
1034807005299	zinc-binding site [ion binding]; other site
1034807005300	Outer membrane protein transport protein (OMPP1/FadL/TodX); Region: Toluene_X; cl17479
1034807005301	ribosomal protein S12 methylthiotransferase RimO; Region: TIGR01125
1034807005302	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1034807005303	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1034807005304	FeS/SAM binding site; other site
1034807005305	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
1034807005306	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1034807005307	ADP binding site [chemical binding]; other site
1034807005308	magnesium binding site [ion binding]; other site
1034807005309	putative shikimate binding site; other site
1034807005310	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
1034807005311	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1034807005312	active site
1034807005313	Restriction endonuclease HincII; Region: Endonuc-HincII; pfam09226
1034807005314	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034807005315	S-adenosylmethionine binding site [chemical binding]; other site
1034807005316	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
1034807005317	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1034807005318	RNA binding surface [nucleotide binding]; other site
1034807005319	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1034807005320	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1034807005321	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034807005322	Walker A/P-loop; other site
1034807005323	ATP binding site [chemical binding]; other site
1034807005324	Q-loop/lid; other site
1034807005325	ABC transporter signature motif; other site
1034807005326	Walker B; other site
1034807005327	D-loop; other site
1034807005328	H-loop/switch region; other site
1034807005329	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1034807005330	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1034807005331	dimer interface [polypeptide binding]; other site
1034807005332	active site
1034807005333	CoA binding pocket [chemical binding]; other site
1034807005334	lycopene cyclase; Region: lycopene_cycl; TIGR01789
1034807005335	Lycopene cyclase protein; Region: Lycopene_cycl; pfam05834
1034807005336	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1034807005337	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
1034807005338	DNA binding residues [nucleotide binding]
1034807005339	B12 binding domain; Region: B12-binding_2; pfam02607
1034807005340	phytoene desaturase; Region: crtI_fam; TIGR02734
1034807005341	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1034807005342	Trans-Isoprenyl Diphosphate Synthases, head-to-head; Region: Trans_IPPS_HH; cd00683
1034807005343	active site lid residues [active]
1034807005344	substrate binding pocket [chemical binding]; other site
1034807005345	catalytic residues [active]
1034807005346	substrate-Mg2+ binding site; other site
1034807005347	aspartate-rich region 1; other site
1034807005348	aspartate-rich region 2; other site
1034807005349	beta-carotene hydroxylase; Region: PLN02601
1034807005350	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1034807005351	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
1034807005352	Putative zinc ribbon domain; Region: DUF164; pfam02591
1034807005353	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1034807005354	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
1034807005355	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3323
1034807005356	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
1034807005357	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1034807005358	Tetraacyldisaccharide-1-P 4'-kinase; Region: LpxK; pfam02606
1034807005359	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
1034807005360	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1034807005361	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034807005362	dimer interface [polypeptide binding]; other site
1034807005363	phosphorylation site [posttranslational modification]
1034807005364	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034807005365	ATP binding site [chemical binding]; other site
1034807005366	Mg2+ binding site [ion binding]; other site
1034807005367	G-X-G motif; other site
1034807005368	Response regulator receiver domain; Region: Response_reg; pfam00072
1034807005369	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034807005370	active site
1034807005371	phosphorylation site [posttranslational modification]
1034807005372	intermolecular recognition site; other site
1034807005373	dimerization interface [polypeptide binding]; other site
1034807005374	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
1034807005375	glyceraldehyde-3-phosphate dehydrogenase, type I; Region: GAPDH-I; TIGR01534
1034807005376	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1034807005377	lipoyl synthase; Provisional; Region: PRK05481
1034807005378	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1034807005379	FeS/SAM binding site; other site
1034807005380	Transmembrane exosortase (Exosortase_EpsH); Region: Exosortase_EpsH; pfam09721
1034807005381	Vault protein inter-alpha-trypsin domain; Region: VIT; cl02699
1034807005382	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
1034807005383	Aconitate hydratase 2 N-terminus; Region: Aconitase_2_N; pfam06434
1034807005384	substrate binding site [chemical binding]; other site
1034807005385	Aconitase catalytic domain; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: Aconitase; cl00285
1034807005386	substrate binding site [chemical binding]; other site
1034807005387	ligand binding site [chemical binding]; other site
1034807005388	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
1034807005389	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
1034807005390	dimer interface [polypeptide binding]; other site
1034807005391	active site
1034807005392	metal binding site [ion binding]; metal-binding site
1034807005393	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_y; TIGR03182
1034807005394	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
1034807005395	tetramer interface [polypeptide binding]; other site
1034807005396	TPP-binding site [chemical binding]; other site
1034807005397	heterodimer interface [polypeptide binding]; other site
1034807005398	phosphorylation loop region [posttranslational modification]
1034807005399	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
1034807005400	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
1034807005401	alpha subunit interface [polypeptide binding]; other site
1034807005402	TPP binding site [chemical binding]; other site
1034807005403	heterodimer interface [polypeptide binding]; other site
1034807005404	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1034807005405	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
1034807005406	TRAM domain; Region: TRAM; cl01282
1034807005407	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034807005408	S-adenosylmethionine binding site [chemical binding]; other site
1034807005409	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
1034807005410	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1034807005411	active site
1034807005412	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
1034807005413	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1034807005414	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1034807005415	Protein of unknown function (DUF3822); Region: DUF3822; pfam12864
1034807005416	Conserved hypothetical protein 95; Region: Cons_hypoth95; pfam03602
1034807005417	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034807005418	S-adenosylmethionine binding site [chemical binding]; other site
1034807005419	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1034807005420	Putative catalytic NodB homology domain of gellan lyase and similar proteins; Region: CE4_GLA_like_6s; cd10967
1034807005421	putative active site [active]
1034807005422	putative metal binding site [ion binding]; other site
1034807005423	Di-haem cytochrome c peroxidase; Region: CCP_MauG; pfam03150
1034807005424	AZL_007920/MXAN_0976 family protein; Region: AZL_007920_fam; TIGR04052
1034807005425	YHYH protein; Region: YHYH; pfam14240
1034807005426	YHYH protein; Region: YHYH; pfam14240
1034807005427	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807005428	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1034807005429	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034807005430	active site
1034807005431	phosphorylation site [posttranslational modification]
1034807005432	intermolecular recognition site; other site
1034807005433	dimerization interface [polypeptide binding]; other site
1034807005434	LytTr DNA-binding domain; Region: LytTR; smart00850
1034807005435	Histidine kinase; Region: His_kinase; pfam06580
1034807005436	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1034807005437	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1034807005438	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
1034807005439	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
1034807005440	Cu(I) binding site [ion binding]; other site
1034807005441	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
1034807005442	YHYH protein; Region: YHYH; pfam14240
1034807005443	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
1034807005444	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
1034807005445	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
1034807005446	CRISPR spacer
1034807005447	CRISPR spacer
1034807005448	CRISPR spacer
1034807005449	CRISPR spacer
1034807005450	CRISPR spacer
1034807005451	CRISPR spacer
1034807005452	CRISPR spacer
1034807005453	CRISPR spacer
1034807005454	CRISPR spacer
1034807005455	CRISPR spacer
1034807005456	CRISPR spacer
1034807005457	CRISPR spacer
1034807005458	CRISPR spacer
1034807005459	CRISPR spacer
1034807005460	CRISPR spacer
1034807005461	CRISPR spacer
1034807005462	CRISPR spacer
1034807005463	CRISPR spacer
1034807005464	CRISPR spacer
1034807005465	CRISPR spacer
1034807005466	CRISPR spacer
1034807005467	CRISPR spacer
1034807005468	CRISPR spacer
1034807005469	CRISPR spacer
1034807005470	CRISPR spacer
1034807005471	CRISPR spacer
1034807005472	CRISPR spacer
1034807005473	CRISPR spacer
1034807005474	CRISPR spacer
1034807005475	CRISPR spacer
1034807005476	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
1034807005477	active site
1034807005478	multimer interface [polypeptide binding]; other site
1034807005479	diaminopimelate decarboxylase; Region: lysA; TIGR01048
1034807005480	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1034807005481	active site
1034807005482	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1034807005483	substrate binding site [chemical binding]; other site
1034807005484	catalytic residues [active]
1034807005485	dimer interface [polypeptide binding]; other site
1034807005486	GH3 auxin-responsive promoter; Region: GH3; pfam03321
1034807005487	Protein of unknown function (DUF2797); Region: DUF2797; pfam10977
1034807005488	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1034807005489	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1034807005490	N-terminal plug; other site
1034807005491	ligand-binding site [chemical binding]; other site
1034807005492	Putative MetA-pathway of phenol degradation; Region: Phenol_MetA_deg; cl01768
1034807005493	di-heme enzyme, MXAN_0977 family; Region: MXAN_0977_Heme2; TIGR04039
1034807005494	Cytochrome c; Region: Cytochrom_C; pfam00034
1034807005495	AZL_007920/MXAN_0976 family protein; Region: AZL_007920_fam; TIGR04052
1034807005496	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1034807005497	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034807005498	dimer interface [polypeptide binding]; other site
1034807005499	phosphorylation site [posttranslational modification]
1034807005500	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034807005501	ATP binding site [chemical binding]; other site
1034807005502	Mg2+ binding site [ion binding]; other site
1034807005503	G-X-G motif; other site
1034807005504	Response regulator receiver domain; Region: Response_reg; pfam00072
1034807005505	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034807005506	active site
1034807005507	phosphorylation site [posttranslational modification]
1034807005508	intermolecular recognition site; other site
1034807005509	dimerization interface [polypeptide binding]; other site
1034807005510	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
1034807005511	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cd00475
1034807005512	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
1034807005513	catalytic residue [active]
1034807005514	putative FPP diphosphate  binding site; other site
1034807005515	putative FPP binding hydrophobic cleft; other site
1034807005516	dimer interface [polypeptide binding]; other site
1034807005517	putative IPP diphosphate binding site; other site
1034807005518	Outer membrane protein/protective antigen OMA87 [Cell envelope biogenesis, outer membrane]; Region: COG4775
1034807005519	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1034807005520	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1034807005521	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1034807005522	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1034807005523	Surface antigen; Region: Bac_surface_Ag; pfam01103
1034807005524	Outer membrane protein (OmpH-like); Region: OmpH; pfam03938
1034807005525	Outer membrane protein (OmpH-like); Region: OmpH; pfam03938
1034807005526	glutamate racemase; Provisional; Region: PRK00865
1034807005527	4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]; Region: UbiA; cl00337
1034807005528	UbiA prenyltransferase family; Region: UbiA; pfam01040
1034807005529	Mevalonate kinase [Lipid metabolism]; Region: ERG12; COG1577
1034807005530	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1034807005531	Mevalonate pyrophosphate decarboxylase [Lipid metabolism]; Region: MVD1; COG3407
1034807005532	diphosphomevalonate decarboxylase; Region: PLN02407
1034807005533	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1034807005534	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1034807005535	Protein of unknown function (DUF2806); Region: DUF2806; cl12560
1034807005536	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
1034807005537	flavoprotein, HI0933 family; Region: TIGR00275
1034807005538	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
1034807005539	Glycerophosphoryl diester phosphodiesterase family; Region: GDPD; pfam03009
1034807005540	active site
1034807005541	catalytic site [active]
1034807005542	Protein of unknown function (DUF420); Region: DUF420; pfam04238
1034807005543	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
1034807005544	Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999
1034807005545	Cu(I) binding site [ion binding]; other site
1034807005546	Prokaryotic Cytochrome C oxidase subunit IV; Region: COX4_pro; pfam03626
1034807005547	Heme-copper oxidase subunit III.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which couple the reduction of molecular oxygen to water to, proton pumping across the membrane. The...; Region: Heme_Cu_Oxidase_III_like; cl00211
1034807005548	Subunit I/III interface [polypeptide binding]; other site
1034807005549	Heme-copper oxidase subunit III.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which couple the reduction of molecular oxygen to water to, proton pumping across the membrane. The...; Region: Heme_Cu_Oxidase_III_like; cl00211
1034807005550	Heme-copper oxidase subunit III.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which couple the reduction of molecular oxygen to water to, proton pumping across the membrane. The...; Region: Heme_Cu_Oxidase_III_like; cl00211
1034807005551	Subunit I/III interface [polypeptide binding]; other site
1034807005552	protoheme IX farnesyltransferase; Provisional; Region: PRK04375
1034807005553	UbiA prenyltransferase family; Region: UbiA; pfam01040
1034807005554	C-terminal peptidase (prc); Region: prc; TIGR00225
1034807005555	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1034807005556	protein binding site [polypeptide binding]; other site
1034807005557	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1034807005558	Catalytic dyad [active]
1034807005559	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
1034807005560	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
1034807005561	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
1034807005562	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
1034807005563	NlpC/P60 family; Region: NLPC_P60; pfam00877
1034807005564	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
1034807005565	Ligand binding site [chemical binding]; other site
1034807005566	Electron transfer flavoprotein domain; Region: ETF; pfam01012
1034807005567	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
1034807005568	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
1034807005569	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
1034807005570	Bifunctional nuclease; Region: DNase-RNase; pfam02577
1034807005571	UvrB/uvrC motif; Region: UVR; pfam02151
1034807005572	thymidylate synthase; Reviewed; Region: thyA; PRK01827
1034807005573	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
1034807005574	dimerization interface [polypeptide binding]; other site
1034807005575	active site
1034807005576	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; Region: ECA_wecA; TIGR02380
1034807005577	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
1034807005578	Mg++ binding site [ion binding]; other site
1034807005579	putative catalytic motif [active]
1034807005580	substrate binding site [chemical binding]; other site
1034807005581	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1034807005582	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_6; cd04955
1034807005583	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1034807005584	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1034807005585	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1034807005586	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1034807005587	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
1034807005588	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
1034807005589	trimer interface [polypeptide binding]; other site
1034807005590	active site
1034807005591	substrate binding site [chemical binding]; other site
1034807005592	CoA binding site [chemical binding]; other site
1034807005593	Thymidylate kinase [Nucleotide transport and metabolism]; Region: Tmk; COG0125
1034807005594	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
1034807005595	active site
1034807005596	O-Antigen ligase; Region: Wzy_C; pfam04932
1034807005597	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1034807005598	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1034807005599	Polysaccharide biosynthesis protein; Region: Polysacc_synt_3; pfam13440
1034807005600	Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane]; Region: GumC; COG3206
1034807005601	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1034807005602	putative polysaccharide export protein, PEP-CTERM sytem-associated; Region: pepcterm_export; TIGR03027
1034807005603	Response regulator receiver domain; Region: Response_reg; pfam00072
1034807005604	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034807005605	active site
1034807005606	phosphorylation site [posttranslational modification]
1034807005607	intermolecular recognition site; other site
1034807005608	dimerization interface [polypeptide binding]; other site
1034807005609	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1034807005610	PAS domain; Region: PAS_9; pfam13426
1034807005611	putative active site [active]
1034807005612	heme pocket [chemical binding]; other site
1034807005613	PAS domain S-box; Region: sensory_box; TIGR00229
1034807005614	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1034807005615	putative active site [active]
1034807005616	heme pocket [chemical binding]; other site
1034807005617	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
1034807005618	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1034807005619	putative active site [active]
1034807005620	heme pocket [chemical binding]; other site
1034807005621	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034807005622	dimer interface [polypeptide binding]; other site
1034807005623	phosphorylation site [posttranslational modification]
1034807005624	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034807005625	ATP binding site [chemical binding]; other site
1034807005626	Mg2+ binding site [ion binding]; other site
1034807005627	G-X-G motif; other site
1034807005628	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1034807005629	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034807005630	active site
1034807005631	phosphorylation site [posttranslational modification]
1034807005632	intermolecular recognition site; other site
1034807005633	dimerization interface [polypeptide binding]; other site
1034807005634	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cl00086
1034807005635	putative binding surface; other site
1034807005636	active site
1034807005637	Uncharacterized conserved protein [Function unknown]; Region: COG3287
1034807005638	FIST N domain; Region: FIST; pfam08495
1034807005639	FIST C domain; Region: FIST_C; pfam10442
1034807005640	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1034807005641	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1034807005642	putative acyl-acceptor binding pocket; other site
1034807005643	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
1034807005644	putative active site [active]
1034807005645	putative CoA binding site [chemical binding]; other site
1034807005646	nudix motif; other site
1034807005647	metal binding site [ion binding]; metal-binding site
1034807005648	Peptidase S8 family domain, uncharacterized subfamily 9; Region: Peptidases_S8_9; cd07493
1034807005649	active site
1034807005650	catalytic triad [active]
1034807005651	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807005652	tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054
1034807005653	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1034807005654	S-adenosyl-L-methionine-dependent methyltransferase; Region: Methyltransf_30; cl17711
1034807005655	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
1034807005656	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224
1034807005657	homodimer interface [polypeptide binding]; other site
1034807005658	substrate-cofactor binding pocket; other site
1034807005659	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034807005660	catalytic residue [active]
1034807005661	Domain of unknown function (DUF4294); Region: DUF4294; pfam14127
1034807005662	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
1034807005663	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
1034807005664	oligomer interface [polypeptide binding]; other site
1034807005665	active site
1034807005666	metal binding site [ion binding]; metal-binding site
1034807005667	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807005668	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
1034807005669	homopentamer interface [polypeptide binding]; other site
1034807005670	active site
1034807005671	Protein-interacting Bro1-like domain of mammalian Alix and related domains; Region: BRO1_Alix_like; cl14649
1034807005672	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
1034807005673	recombination protein F; Reviewed; Region: recF; PRK00064
1034807005674	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034807005675	Walker A/P-loop; other site
1034807005676	ATP binding site [chemical binding]; other site
1034807005677	Q-loop/lid; other site
1034807005678	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034807005679	ABC transporter signature motif; other site
1034807005680	Walker B; other site
1034807005681	D-loop; other site
1034807005682	H-loop/switch region; other site
1034807005683	Shikimate 5-dehydrogenase [Amino acid transport and metabolism]; Region: AroE; COG0169
1034807005684	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1034807005685	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1034807005686	shikimate binding site; other site
1034807005687	NAD(P) binding site [chemical binding]; other site
1034807005688	TPR repeat; Region: TPR_11; pfam13414
1034807005689	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034807005690	binding surface
1034807005691	TPR motif; other site
1034807005692	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034807005693	binding surface
1034807005694	TPR repeat; Region: TPR_11; pfam13414
1034807005695	TPR motif; other site
1034807005696	TPR repeat; Region: TPR_11; pfam13414
1034807005697	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034807005698	binding surface
1034807005699	TPR motif; other site
1034807005700	TPR repeat; Region: TPR_11; pfam13414
1034807005701	Protein of unknown function (DUF779); Region: DUF779; pfam05610
1034807005702	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
1034807005703	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1034807005704	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1034807005705	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1034807005706	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1034807005707	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034807005708	non-specific DNA binding site [nucleotide binding]; other site
1034807005709	salt bridge; other site
1034807005710	sequence-specific DNA binding site [nucleotide binding]; other site
1034807005711	Plasmid maintenance system killer protein; Region: Plasmid_killer; cl01422
1034807005712	Protein of unknown function (DUF3732); Region: DUF3732; pfam12532
1034807005713	Transposase IS200 like; Region: Y1_Tnp; cl00848
1034807005714	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
1034807005715	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
1034807005716	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1034807005717	ATP binding site [chemical binding]; other site
1034807005718	putative Mg++ binding site [ion binding]; other site
1034807005719	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1034807005720	PIF1-like helicase; Region: PIF1; pfam05970
1034807005721	AAA domain; Region: AAA_30; pfam13604
1034807005722	Family description; Region: UvrD_C_2; pfam13538
1034807005723	Helix-turn-helix domain; Region: HTH_17; pfam12728
1034807005724	Protein of unknown function (DUF3946); Region: DUF3946; pfam13102
1034807005725	Tn4399 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, N- and C-terminal domains. This CD includes various bacterial integrases, including cLV25, a Bacteroides fragilis chromosomal transfer factor integrase similar to the...; Region: INT_Tn4399; cd01185
1034807005726	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
1034807005727	Int/Topo IB signature motif; other site
1034807005728	Helix-turn-helix domain; Region: HTH_17; pfam12728
1034807005729	Protein of unknown function (DUF3946); Region: DUF3946; pfam13102
1034807005730	Tn4399 and related integrases, DNA breaking-rejoining enzymes, integrase/recombinases, N- and C-terminal domains. This CD includes various bacterial integrases, including cLV25, a Bacteroides fragilis chromosomal transfer factor integrase similar to the...; Region: INT_Tn4399; cd01185
1034807005731	Int/Topo IB signature motif; other site
1034807005732	Helix-turn-helix domain; Region: HTH_17; cl17695
1034807005733	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
1034807005734	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1034807005735	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1034807005736	G1 box; other site
1034807005737	GTP/Mg2+ binding site [chemical binding]; other site
1034807005738	Switch I region; other site
1034807005739	G2 box; other site
1034807005740	Switch II region; other site
1034807005741	G3 box; other site
1034807005742	G4 box; other site
1034807005743	G5 box; other site
1034807005744	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1034807005745	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1034807005746	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1034807005747	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
1034807005748	Walker A/P-loop; other site
1034807005749	ATP binding site [chemical binding]; other site
1034807005750	Q-loop/lid; other site
1034807005751	ABC transporter signature motif; other site
1034807005752	Walker B; other site
1034807005753	D-loop; other site
1034807005754	H-loop/switch region; other site
1034807005755	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1034807005756	nucleoside/Zn binding site; other site
1034807005757	dimer interface [polypeptide binding]; other site
1034807005758	catalytic motif [active]
1034807005759	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
1034807005760	Chloramphenicol acetyltransferase; Region: CAT; smart01059
1034807005761	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it, thus inhibiting its potentially lethal RNase activity inside the...; Region: Barstar_like; cl01048
1034807005762	RNAase interaction site [polypeptide binding]; other site
1034807005763	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
1034807005764	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
1034807005765	magnesium chelatase subunit H; Provisional; Region: PRK12493
1034807005766	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4152
1034807005767	ATP-binding cassette domain of an uncharacterized transporter; Region: ABC_putative_ATPase; cd03269
1034807005768	Walker A/P-loop; other site
1034807005769	ATP binding site [chemical binding]; other site
1034807005770	Q-loop/lid; other site
1034807005771	ABC transporter signature motif; other site
1034807005772	Walker B; other site
1034807005773	D-loop; other site
1034807005774	H-loop/switch region; other site
1034807005775	Domain of unknown function (DUF4162); Region: DUF4162; pfam13732
1034807005776	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
1034807005777	Response regulator receiver domain; Region: Response_reg; pfam00072
1034807005778	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034807005779	active site
1034807005780	phosphorylation site [posttranslational modification]
1034807005781	intermolecular recognition site; other site
1034807005782	dimerization interface [polypeptide binding]; other site
1034807005783	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034807005784	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1034807005785	Walker A motif; other site
1034807005786	ATP binding site [chemical binding]; other site
1034807005787	Walker B motif; other site
1034807005788	arginine finger; other site
1034807005789	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1034807005790	DEAD-like helicases superfamily; Region: DEXDc; smart00487
1034807005791	ATP binding site [chemical binding]; other site
1034807005792	putative Mg++ binding site [ion binding]; other site
1034807005793	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547
1034807005794	Transposase; Region: DEDD_Tnp_IS110; pfam01548
1034807005795	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
1034807005796	Domain of unknown function (DUF2007); Region: DUF2007; pfam09413
1034807005797	exonuclease SbcC; Region: sbcc; TIGR00618
1034807005798	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034807005799	Walker A/P-loop; other site
1034807005800	ATP binding site [chemical binding]; other site
1034807005801	Q-loop/lid; other site
1034807005802	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034807005803	ABC transporter signature motif; other site
1034807005804	Walker B; other site
1034807005805	D-loop; other site
1034807005806	H-loop/switch region; other site
1034807005807	DNA repair exonuclease [DNA replication, recombination, and repair]; Region: SbcD; COG0420
1034807005808	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
1034807005809	active site
1034807005810	metal binding site [ion binding]; metal-binding site
1034807005811	DNA binding site [nucleotide binding]
1034807005812	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1034807005813	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
1034807005814	dimer interface [polypeptide binding]; other site
1034807005815	gliding motility-associated C-terminal domain; Region: Bac_Flav_CTERM; TIGR04131
1034807005816	gliding motility-associated C-terminal domain; Region: Bac_Flav_CTERM; TIGR04131
1034807005817	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
1034807005818	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
1034807005819	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1034807005820	active site
1034807005821	HIGH motif; other site
1034807005822	nucleotide binding site [chemical binding]; other site
1034807005823	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1034807005824	KMSK motif region; other site
1034807005825	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1034807005826	tRNA binding surface [nucleotide binding]; other site
1034807005827	anticodon binding site; other site
1034807005828	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1034807005829	SGNH_peri1; putative periplasmic member of the SGNH-family of hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known...; Region: SGNH_hydrolase_peri1; cd01825
1034807005830	active site
1034807005831	oxyanion hole [active]
1034807005832	catalytic triad [active]
1034807005833	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1034807005834	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034807005835	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1034807005836	active site
1034807005837	oxyanion hole [active]
1034807005838	catalytic triad [active]
1034807005839	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
1034807005840	signal recognition particle protein; Provisional; Region: PRK10867
1034807005841	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1034807005842	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1034807005843	P loop; other site
1034807005844	GTP binding site [chemical binding]; other site
1034807005845	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1034807005846	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14185
1034807005847	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1034807005848	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1034807005849	homodimer interface [polypeptide binding]; other site
1034807005850	NADP binding site [chemical binding]; other site
1034807005851	substrate binding site [chemical binding]; other site
1034807005852	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
1034807005853	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
1034807005854	Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases; Region: SCAD_SBCAD; cd01158
1034807005855	FAD binding site [chemical binding]; other site
1034807005856	homotetramer interface [polypeptide binding]; other site
1034807005857	substrate binding pocket [chemical binding]; other site
1034807005858	catalytic base [active]
1034807005859	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
1034807005860	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
1034807005861	Protein of unknown function (DUF2851); Region: DUF2851; pfam11013
1034807005862	cystathionine beta-synthase; Region: cysta_beta; TIGR01137
1034807005863	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1034807005864	dimer interface [polypeptide binding]; other site
1034807005865	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034807005866	catalytic residue [active]
1034807005867	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the pyridoxal-phosphate (PALP) dependent enzyme domain upstream.   The vitamin B6 complex comprises pyridoxine, pyridoxal, and pyridoxamine, as well...; Region: CBS_pair_PALP_assoc2; cd04609
1034807005868	Domain of unknown function (DUF4289); Region: DUF4289; pfam14121
1034807005869	Zinc metalloprotease (elastase) [Amino acid transport and metabolism]; Region: LasB; COG3227
1034807005870	Fungalysin/Thermolysin Propeptide Motif; Region: FTP; pfam07504
1034807005871	Peptidase M4 family includes thermolysin, protealysin, aureolysin and neutral protease; Region: M4_neutral_protease; cd09597
1034807005872	active site
1034807005873	Zn binding site [ion binding]; other site
1034807005874	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807005875	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
1034807005876	PA_subtilisin_1: Protease-associated domain containing subtilisin-like proteases, subgroup 1. A subgroup of PA domain-containing subtilisin-like proteases. The significance of the PA domain to many of the proteins in which it is inserted is undetermined; Region: PA_subtilisin_1; cd04818
1034807005877	PA/protease or protease-like domain interface [polypeptide binding]; other site
1034807005878	Peptidase M36 family also known as fungalysin family; Region: M36; cd09596
1034807005879	Zn binding site [ion binding]; other site
1034807005880	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807005881	starch binding outer membrane protein SusD; Region: SusD; cl17845
1034807005882	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
1034807005883	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1034807005884	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1034807005885	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1034807005886	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1034807005887	RNA/DNA hybrid binding site [nucleotide binding]; other site
1034807005888	active site
1034807005889	gliding motility-associated protein GldC; Region: GldC; TIGR03515
1034807005890	gliding motility-associated lipoprotein GldB; Region: GldB_lipo; TIGR03514
1034807005891	NAD synthase [Coenzyme metabolism]; Region: NadE; COG0171
1034807005892	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
1034807005893	homodimer interface [polypeptide binding]; other site
1034807005894	NAD binding pocket [chemical binding]; other site
1034807005895	ATP binding pocket [chemical binding]; other site
1034807005896	Mg binding site [ion binding]; other site
1034807005897	active-site loop [active]
1034807005898	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1034807005899	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034807005900	active site
1034807005901	phosphorylation site [posttranslational modification]
1034807005902	intermolecular recognition site; other site
1034807005903	dimerization interface [polypeptide binding]; other site
1034807005904	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1034807005905	DNA binding residues [nucleotide binding]
1034807005906	dimerization interface [polypeptide binding]; other site
1034807005907	DNA primase, catalytic core; Region: dnaG; TIGR01391
1034807005908	CHC2 zinc finger; Region: zf-CHC2; cl17510
1034807005909	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1034807005910	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1034807005911	active site
1034807005912	metal binding site [ion binding]; metal-binding site
1034807005913	interdomain interaction site; other site
1034807005914	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
1034807005915	Zn-dependent oligopeptidases [Amino acid transport and metabolism]; Region: Dcp; COG0339
1034807005916	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
1034807005917	active site
1034807005918	Zn binding site [ion binding]; other site
1034807005919	AIR carboxylase; Region: AIRC; pfam00731
1034807005920	urocanate hydratase; Provisional; Region: PRK05414
1034807005921	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1034807005922	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1034807005923	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1034807005924	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
1034807005925	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1034807005926	inhibitor-cofactor binding pocket; inhibition site
1034807005927	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034807005928	catalytic residue [active]
1034807005929	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; pfam01832
1034807005930	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034807005931	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1034807005932	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034807005933	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1034807005934	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034807005935	1-aminocyclopropane-1-carboxylate deaminase [Amino acid transport and metabolism]; Region: Acd; COG2515
1034807005936	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
1034807005937	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1034807005938	catalytic residue [active]
1034807005939	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1034807005940	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1034807005941	substrate binding pocket [chemical binding]; other site
1034807005942	chain length determination region; other site
1034807005943	substrate-Mg2+ binding site; other site
1034807005944	catalytic residues [active]
1034807005945	aspartate-rich region 1; other site
1034807005946	active site lid residues [active]
1034807005947	aspartate-rich region 2; other site
1034807005948	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807005949	Acyl-protein synthetase, LuxE; Region: LuxE; pfam04443
1034807005950	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1034807005951	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1034807005952	RNA binding surface [nucleotide binding]; other site
1034807005953	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1034807005954	active site
1034807005955	DNA alkylation repair enzyme; Region: DNA_alkylation; pfam08713
1034807005956	A new structural DNA glycosylase containing HEAT-like repeats; Region: AlkD_like_1; cd07064
1034807005957	active site
1034807005958	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
1034807005959	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034807005960	Walker A motif; other site
1034807005961	ATP binding site [chemical binding]; other site
1034807005962	Walker B motif; other site
1034807005963	arginine finger; other site
1034807005964	Cyclomaltodextrinase, N-terminal; Region: Cyc-maltodext_N; pfam09087
1034807005965	Alpha amylase catalytic domain found in bacterial cyclomaltodextrinases and related proteins; Region: AmyAc_bac_CMD_like_3; cd11340
1034807005966	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
1034807005967	Ca binding site [ion binding]; other site
1034807005968	active site
1034807005969	homodimer interface [polypeptide binding]; other site
1034807005970	catalytic site [active]
1034807005971	Cyclo-malto-dextrinase C-terminal domain; Region: Cyc-maltodext_C; pfam10438
1034807005972	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1034807005973	maltose phosphorylase; Provisional; Region: PRK13807
1034807005974	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
1034807005975	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
1034807005976	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
1034807005977	beta-phosphoglucomutase; Region: bPGM; TIGR01990
1034807005978	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034807005979	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1034807005980	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1034807005981	DNA binding site [nucleotide binding]
1034807005982	domain linker motif; other site
1034807005983	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1034807005984	dimerization interface [polypeptide binding]; other site
1034807005985	ligand binding site [chemical binding]; other site
1034807005986	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1034807005987	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
1034807005988	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1034807005989	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1034807005990	starch binding outer membrane protein SusD; Region: SusD; cd08977
1034807005991	SusE outer membrane protein; Region: SusE; pfam14292
1034807005992	Uncharacterized subgroup of the CBM-SusE-F_like superfamily; Region: CBM_SusE-F_like_u1; cd12967
1034807005993	starch binding site [chemical binding]; other site
1034807005994	carbohydrate-binding modules from Bacteroides thetaiotaomicron SusE, SusF and similar proteins; Region: CBM_SusE-F_like; cd12956
1034807005995	starch binding site [chemical binding]; other site
1034807005996	Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus; Region: E_set; cl09101
1034807005997	Alpha amylase catalytic domain found in an uncharacterized protein family; Region: AmyAc_4; cd11350
1034807005998	active site
1034807005999	catalytic site [active]
1034807006000	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807006001	gliding motility-associated C-terminal domain; Region: Bac_Flav_CTERM; TIGR04131
1034807006002	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1034807006003	PCRF domain; Region: PCRF; pfam03462
1034807006004	RF-1 domain; Region: RF-1; pfam00472
1034807006005	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1034807006006	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1034807006007	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
1034807006008	DNA binding residues [nucleotide binding]
1034807006009	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1034807006010	rRNA methylase, putative, group 3; Region: rRNA_methyl_3; TIGR00186
1034807006011	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1034807006012	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1034807006013	E3 interaction surface; other site
1034807006014	lipoyl attachment site [posttranslational modification]; other site
1034807006015	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
1034807006016	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
1034807006017	E3 interaction surface; other site
1034807006018	lipoyl attachment site [posttranslational modification]; other site
1034807006019	e3 binding domain; Region: E3_binding; pfam02817
1034807006020	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
1034807006021	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_y; TIGR03182
1034807006022	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
1034807006023	tetramer interface [polypeptide binding]; other site
1034807006024	TPP-binding site [chemical binding]; other site
1034807006025	heterodimer interface [polypeptide binding]; other site
1034807006026	phosphorylation loop region [posttranslational modification]
1034807006027	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1034807006028	active site
1034807006029	dimer interface [polypeptide binding]; other site
1034807006030	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1034807006031	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1034807006032	intersubunit interface [polypeptide binding]; other site
1034807006033	Protein of unknown function (DUF4197); Region: DUF4197; pfam13852
1034807006034	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
1034807006035	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1034807006036	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1034807006037	trimer interface [polypeptide binding]; other site
1034807006038	active site
1034807006039	UDP-GlcNAc binding site [chemical binding]; other site
1034807006040	lipid binding site [chemical binding]; lipid-binding site
1034807006041	Glycosyl hydrolases family 32; Region: Glyco_32; smart00640
1034807006042	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
1034807006043	substrate binding [chemical binding]; other site
1034807006044	active site
1034807006045	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
1034807006046	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
1034807006047	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034807006048	putative substrate translocation pore; other site
1034807006049	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034807006050	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1034807006051	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
1034807006052	putative substrate binding site [chemical binding]; other site
1034807006053	putative ATP binding site [chemical binding]; other site
1034807006054	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1034807006055	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
1034807006056	active site
1034807006057	metal binding site [ion binding]; metal-binding site
1034807006058	peptidase T; Region: peptidase-T; TIGR01882
1034807006059	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1034807006060	metal binding site [ion binding]; metal-binding site
1034807006061	dimer interface [polypeptide binding]; other site
1034807006062	Protein of unknown function (DUF1398); Region: DUF1398; cl11576
1034807006063	Predicted transcriptional regulators [Transcription]; Region: COG1510
1034807006064	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1034807006065	dimerization interface [polypeptide binding]; other site
1034807006066	putative DNA binding site [nucleotide binding]; other site
1034807006067	putative Zn2+ binding site [ion binding]; other site
1034807006068	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1034807006069	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034807006070	S-adenosylmethionine binding site [chemical binding]; other site
1034807006071	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1034807006072	TIGR01777 family protein; Region: yfcH
1034807006073	NAD(P) binding site [chemical binding]; other site
1034807006074	active site
1034807006075	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
1034807006076	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807006077	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807006078	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1034807006079	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034807006080	active site
1034807006081	phosphorylation site [posttranslational modification]
1034807006082	intermolecular recognition site; other site
1034807006083	dimerization interface [polypeptide binding]; other site
1034807006084	LytTr DNA-binding domain; Region: LytTR; smart00850
1034807006085	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1034807006086	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034807006087	binding surface
1034807006088	TPR motif; other site
1034807006089	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034807006090	binding surface
1034807006091	TPR motif; other site
1034807006092	Histidine kinase; Region: His_kinase; pfam06580
1034807006093	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034807006094	ATP binding site [chemical binding]; other site
1034807006095	Mg2+ binding site [ion binding]; other site
1034807006096	G-X-G motif; other site
1034807006097	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
1034807006098	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
1034807006099	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807006100	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
1034807006101	Part of AAA domain; Region: AAA_19; pfam13245
1034807006102	Family description; Region: UvrD_C_2; pfam13538
1034807006103	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
1034807006104	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
1034807006105	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1034807006106	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1034807006107	Protein of unknown function (DUF2004); Region: DUF2004; pfam09406
1034807006108	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1034807006109	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1034807006110	Coenzyme A binding pocket [chemical binding]; other site
1034807006111	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
1034807006112	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
1034807006113	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1034807006114	Protein export membrane protein; Region: SecD_SecF; cl14618
1034807006115	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1034807006116	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1034807006117	HlyD family secretion protein; Region: HlyD_3; pfam13437
1034807006118	Protein of unknown function (DUF3810); Region: DUF3810; pfam12725
1034807006119	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1034807006120	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1034807006121	RNA binding surface [nucleotide binding]; other site
1034807006122	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
1034807006123	probable active site [active]
1034807006124	Domain of unknown function (DUF4252); Region: DUF4252; pfam14060
1034807006125	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
1034807006126	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1034807006127	PYR/PP interface [polypeptide binding]; other site
1034807006128	dimer interface [polypeptide binding]; other site
1034807006129	TPP binding site [chemical binding]; other site
1034807006130	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1034807006131	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1034807006132	transketolase; Reviewed; Region: PRK05899
1034807006133	TPP-binding site [chemical binding]; other site
1034807006134	dimer interface [polypeptide binding]; other site
1034807006135	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1034807006136	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034807006137	dimer interface [polypeptide binding]; other site
1034807006138	phosphorylation site [posttranslational modification]
1034807006139	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034807006140	ATP binding site [chemical binding]; other site
1034807006141	Mg2+ binding site [ion binding]; other site
1034807006142	G-X-G motif; other site
1034807006143	Response regulator receiver domain; Region: Response_reg; pfam00072
1034807006144	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034807006145	active site
1034807006146	phosphorylation site [posttranslational modification]
1034807006147	intermolecular recognition site; other site
1034807006148	dimerization interface [polypeptide binding]; other site
1034807006149	Hpt domain; Region: Hpt; pfam01627
1034807006150	Lipid A 3-O-deacylase (PagL); Region: PagL; pfam09411
1034807006151	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
1034807006152	UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Region: alt_bact_glmU; TIGR03991
1034807006153	Sugar nucleotidyl transferase; Region: NTP_transf_4; pfam13562
1034807006154	Uncharacterized proteins, Left-handed parallel beta-Helix (LbH) domain: Members in this group are uncharacterized bacterial proteins containing a LbH domain with multiple turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif...; Region: LbH_unknown; cd05635
1034807006155	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
1034807006156	Protein of unknown function (DUF4199); Region: DUF4199; pfam13858
1034807006157	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
1034807006158	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
1034807006159	Ligand binding site; other site
1034807006160	Putative Catalytic site; other site
1034807006161	DXD motif; other site
1034807006162	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
1034807006163	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
1034807006164	active site
1034807006165	substrate binding site [chemical binding]; other site
1034807006166	metal binding site [ion binding]; metal-binding site
1034807006167	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1034807006168	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1034807006169	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1034807006170	Walker A/P-loop; other site
1034807006171	ATP binding site [chemical binding]; other site
1034807006172	Q-loop/lid; other site
1034807006173	ABC transporter signature motif; other site
1034807006174	Walker B; other site
1034807006175	D-loop; other site
1034807006176	H-loop/switch region; other site
1034807006177	Glycosyl hydrolase family 53; Region: Glyco_hydro_53; cl06672
1034807006178	amino acid transporter; Region: 2A0306; TIGR00909
1034807006179	C-terminus of AA_permease; Region: AA_permease_C; pfam13906
1034807006180	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1034807006181	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1034807006182	dimer interface [polypeptide binding]; other site
1034807006183	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1034807006184	catalytic triad [active]
1034807006185	peroxidatic and resolving cysteines [active]
1034807006186	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1034807006187	catalytic residues [active]
1034807006188	Outer membrane protein family (DUF1597); Region: DUF1597; pfam07642
1034807006189	K+ potassium transporter; Region: K_trans; pfam02705
1034807006190	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1034807006191	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034807006192	active site
1034807006193	phosphorylation site [posttranslational modification]
1034807006194	intermolecular recognition site; other site
1034807006195	dimerization interface [polypeptide binding]; other site
1034807006196	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1034807006197	DNA binding site [nucleotide binding]
1034807006198	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034807006199	dimer interface [polypeptide binding]; other site
1034807006200	phosphorylation site [posttranslational modification]
1034807006201	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034807006202	ATP binding site [chemical binding]; other site
1034807006203	Mg2+ binding site [ion binding]; other site
1034807006204	G-X-G motif; other site
1034807006205	Arsenite efflux pump ACR3 and related permeases [Inorganic ion transport and metabolism]; Region: ACR3; COG0798
1034807006206	arsenical-resistance protein; Region: acr3; TIGR00832
1034807006207	Low molecular weight phosphatase family; Region: LMWPc; cl00105
1034807006208	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1034807006209	dimerization interface [polypeptide binding]; other site
1034807006210	putative DNA binding site [nucleotide binding]; other site
1034807006211	putative Zn2+ binding site [ion binding]; other site
1034807006212	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
1034807006213	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
1034807006214	BON domain; Region: BON; pfam04972
1034807006215	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1034807006216	hypothetical protein; Reviewed; Region: PRK00024
1034807006217	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1034807006218	MPN+ (JAMM) motif; other site
1034807006219	Zinc-binding site [ion binding]; other site
1034807006220	HAD superfamily (subfamily IA) hydrolase, TIGR02254; Region: YjjG/YfnB
1034807006221	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034807006222	motif II; other site
1034807006223	recombination factor protein RarA; Reviewed; Region: PRK13342
1034807006224	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034807006225	Walker A motif; other site
1034807006226	ATP binding site [chemical binding]; other site
1034807006227	Walker B motif; other site
1034807006228	arginine finger; other site
1034807006229	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1034807006230	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1034807006231	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1034807006232	Peptidase family M23; Region: Peptidase_M23; pfam01551
1034807006233	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1034807006234	Cell shape-determining protein [Cell envelope biogenesis, outer membrane]; Region: MreC; COG1792
1034807006235	Cell division protein ZapA; Region: ZapA; pfam05164
1034807006236	phosphodiesterase; Provisional; Region: PRK12704
1034807006237	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1034807006238	Zn2+ binding site [ion binding]; other site
1034807006239	Mg2+ binding site [ion binding]; other site
1034807006240	Protein of unknown function (DUF1697); Region: DUF1697; pfam08002
1034807006241	Peptidase S46; Region: Peptidase_S46; pfam10459
1034807006242	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1034807006243	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
1034807006244	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
1034807006245	metal binding site [ion binding]; metal-binding site
1034807006246	dimer interface [polypeptide binding]; other site
1034807006247	Glutamate synthase domain 2 [Amino acid transport and metabolism]; Region: GltB; COG0069
1034807006248	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
1034807006249	active site
1034807006250	FMN binding site [chemical binding]; other site
1034807006251	substrate binding site [chemical binding]; other site
1034807006252	3Fe-4S cluster binding site [ion binding]; other site
1034807006253	UDP-N-acetylglucosamine 4-epimerase, extended (e) SDRs; Region: UDP_AE_SDR_e; cd05256
1034807006254	Vi polysaccharide biosynthesis protein TviC; Provisional; Region: PRK15181
1034807006255	NAD binding site [chemical binding]; other site
1034807006256	substrate binding site [chemical binding]; other site
1034807006257	homodimer interface [polypeptide binding]; other site
1034807006258	active site
1034807006259	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1034807006260	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
1034807006261	active site
1034807006262	DNA binding site [nucleotide binding]
1034807006263	Int/Topo IB signature motif; other site
1034807006264	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
1034807006265	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
1034807006266	active site
1034807006267	bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase/(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; Reviewed; Region: PRK13188
1034807006268	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
1034807006269	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1034807006270	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
1034807006271	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1034807006272	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1034807006273	trimer interface [polypeptide binding]; other site
1034807006274	active site
1034807006275	UDP-GlcNAc binding site [chemical binding]; other site
1034807006276	lipid binding site [chemical binding]; lipid-binding site
1034807006277	HD superfamily phosphohydrolases [General function prediction only]; Region: COG1078
1034807006278	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1034807006279	Zn2+ binding site [ion binding]; other site
1034807006280	Mg2+ binding site [ion binding]; other site
1034807006281	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1034807006282	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1034807006283	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
1034807006284	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1034807006285	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1034807006286	active site
1034807006287	dimer interface [polypeptide binding]; other site
1034807006288	motif 1; other site
1034807006289	motif 2; other site
1034807006290	motif 3; other site
1034807006291	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1034807006292	anticodon binding site; other site
1034807006293	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1034807006294	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1034807006295	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1034807006296	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1034807006297	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1034807006298	23S rRNA binding site [nucleotide binding]; other site
1034807006299	L21 binding site [polypeptide binding]; other site
1034807006300	L13 binding site [polypeptide binding]; other site
1034807006301	Mycoplasma pulmonis MnuA nuclease-like; Region: MnuA_DNase1-like; cd10283
1034807006302	putative active site [active]
1034807006303	putative catalytic site [active]
1034807006304	putative Mg binding site IVb [ion binding]; other site
1034807006305	putative phosphate binding site [ion binding]; other site
1034807006306	putative DNA binding site [nucleotide binding]; other site
1034807006307	putative Mg binding site IVa [ion binding]; other site
1034807006308	Predicted helicase [General function prediction only]; Region: COG4889
1034807006309	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1034807006310	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1034807006311	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1034807006312	ABC transporter; Region: ABC_tran_2; pfam12848
1034807006313	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1034807006314	Predicted helicase [General function prediction only]; Region: COG4889
1034807006315	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
1034807006316	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
1034807006317	Virulence protein RhuM family; Region: Virulence_RhuM; pfam13310
1034807006318	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C); Region: NT5C; cl17836
1034807006319	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1034807006320	Uncharacterized protein family (UPF0227); Region: UPF0227; cl14886
1034807006321	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
1034807006322	ISXO2-like transposase domain; Region: DDE_Tnp_IS1595; pfam12762
1034807006323	WYL domain; Region: WYL; pfam13280
1034807006324	Protein of unknown function DUF262; Region: DUF262; pfam03235
1034807006325	Uncharacterized conserved protein [Function unknown]; Region: COG1479
1034807006326	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
1034807006327	multidrug efflux protein; Reviewed; Region: PRK01766
1034807006328	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
1034807006329	cation binding site [ion binding]; other site
1034807006330	GrpE; Region: GrpE; pfam01025
1034807006331	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1034807006332	dimer interface [polypeptide binding]; other site
1034807006333	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1034807006334	chaperone protein DnaJ; Provisional; Region: PRK14289
1034807006335	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1034807006336	HSP70 interaction site [polypeptide binding]; other site
1034807006337	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1034807006338	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1034807006339	dimer interface [polypeptide binding]; other site
1034807006340	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
1034807006341	Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537
1034807006342	Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971
1034807006343	Cupin domain; Region: Cupin_2; pfam07883
1034807006344	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1034807006345	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1034807006346	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1034807006347	Protein of unknown function (DUF493); Region: DUF493; cl01102
1034807006348	Domain of unknown function (DUF4290); Region: DUF4290; pfam14123
1034807006349	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1034807006350	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1034807006351	hinge; other site
1034807006352	active site
1034807006353	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1034807006354	Cation efflux family; Region: Cation_efflux; pfam01545
1034807006355	putative hydrolase; Provisional; Region: PRK10976
1034807006356	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1034807006357	active site
1034807006358	motif I; other site
1034807006359	motif II; other site
1034807006360	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
1034807006361	dimer interface [polypeptide binding]; other site
1034807006362	Citrate synthase; Region: Citrate_synt; pfam00285
1034807006363	active site
1034807006364	citrylCoA binding site [chemical binding]; other site
1034807006365	NADH binding [chemical binding]; other site
1034807006366	cationic pore residues; other site
1034807006367	oxalacetate/citrate binding site [chemical binding]; other site
1034807006368	coenzyme A binding site [chemical binding]; other site
1034807006369	catalytic triad [active]
1034807006370	enolase; Provisional; Region: eno; PRK00077
1034807006371	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1034807006372	dimer interface [polypeptide binding]; other site
1034807006373	metal binding site [ion binding]; metal-binding site
1034807006374	substrate binding pocket [chemical binding]; other site
1034807006375	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
1034807006376	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
1034807006377	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1034807006378	catalytic site [active]
1034807006379	subunit interface [polypeptide binding]; other site
1034807006380	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
1034807006381	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1034807006382	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1034807006383	alphaNTD homodimer interface [polypeptide binding]; other site
1034807006384	alphaNTD - beta interaction site [polypeptide binding]; other site
1034807006385	alphaNTD - beta' interaction site [polypeptide binding]; other site
1034807006386	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1034807006387	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1034807006388	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1034807006389	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1034807006390	RNA binding surface [nucleotide binding]; other site
1034807006391	30S ribosomal protein S11; Validated; Region: PRK05309
1034807006392	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1034807006393	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1034807006394	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
1034807006395	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1034807006396	rRNA binding site [nucleotide binding]; other site
1034807006397	predicted 30S ribosome binding site; other site
1034807006398	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1034807006399	SecY translocase; Region: SecY; pfam00344
1034807006400	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1034807006401	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1034807006402	23S rRNA binding site [nucleotide binding]; other site
1034807006403	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1034807006404	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1034807006405	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1034807006406	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1034807006407	5S rRNA interface [nucleotide binding]; other site
1034807006408	L27 interface [polypeptide binding]; other site
1034807006409	23S rRNA interface [nucleotide binding]; other site
1034807006410	L5 interface [polypeptide binding]; other site
1034807006411	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1034807006412	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1034807006413	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1034807006414	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1034807006415	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
1034807006416	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1034807006417	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1034807006418	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1034807006419	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1034807006420	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1034807006421	RNA binding site [nucleotide binding]; other site
1034807006422	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1034807006423	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1034807006424	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1034807006425	23S rRNA interface [nucleotide binding]; other site
1034807006426	putative translocon interaction site; other site
1034807006427	signal recognition particle (SRP54) interaction site; other site
1034807006428	L23 interface [polypeptide binding]; other site
1034807006429	trigger factor interaction site; other site
1034807006430	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1034807006431	23S rRNA interface [nucleotide binding]; other site
1034807006432	5S rRNA interface [nucleotide binding]; other site
1034807006433	putative antibiotic binding site [chemical binding]; other site
1034807006434	L25 interface [polypeptide binding]; other site
1034807006435	L27 interface [polypeptide binding]; other site
1034807006436	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1034807006437	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1034807006438	G-X-X-G motif; other site
1034807006439	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1034807006440	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1034807006441	putative translocon binding site; other site
1034807006442	protein-rRNA interface [nucleotide binding]; other site
1034807006443	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1034807006444	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1034807006445	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1034807006446	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1034807006447	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1034807006448	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1034807006449	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
1034807006450	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1034807006451	G1 box; other site
1034807006452	GTP/Mg2+ binding site [chemical binding]; other site
1034807006453	Switch I region; other site
1034807006454	G2 box; other site
1034807006455	G3 box; other site
1034807006456	Switch II region; other site
1034807006457	G4 box; other site
1034807006458	G5 box; other site
1034807006459	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1034807006460	active site
1034807006461	C4-type Zn-finger protein [General function prediction only]; Region: COG1779
1034807006462	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1034807006463	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1034807006464	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1034807006465	ABC transporter; Region: ABC_tran_2; pfam12848
1034807006466	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1034807006467	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
1034807006468	GTPase Era; Reviewed; Region: era; PRK00089
1034807006469	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1034807006470	G1 box; other site
1034807006471	GTP/Mg2+ binding site [chemical binding]; other site
1034807006472	Switch I region; other site
1034807006473	G2 box; other site
1034807006474	Switch II region; other site
1034807006475	G3 box; other site
1034807006476	G4 box; other site
1034807006477	G5 box; other site
1034807006478	KH domain; Region: KH_2; pfam07650
1034807006479	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1034807006480	global nitrogen regulator NtcA, cyanobacterial; Region: NtcA_cyano; TIGR03697
1034807006481	ligand binding site [chemical binding]; other site
1034807006482	flexible hinge region; other site
1034807006483	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1034807006484	non-specific DNA interactions [nucleotide binding]; other site
1034807006485	DNA binding site [nucleotide binding]
1034807006486	sequence specific DNA binding site [nucleotide binding]; other site
1034807006487	putative cAMP binding site [chemical binding]; other site
1034807006488	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
1034807006489	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
1034807006490	heme-binding site [chemical binding]; other site
1034807006491	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
1034807006492	FAD binding pocket [chemical binding]; other site
1034807006493	FAD binding motif [chemical binding]; other site
1034807006494	phosphate binding motif [ion binding]; other site
1034807006495	beta-alpha-beta structure motif; other site
1034807006496	NAD binding pocket [chemical binding]; other site
1034807006497	Heme binding  pocket [chemical binding]; other site
1034807006498	Protein of unknown function (DUF2798); Region: DUF2798; pfam11391
1034807006499	GTP-binding protein Der; Reviewed; Region: PRK00093
1034807006500	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1034807006501	G1 box; other site
1034807006502	GTP/Mg2+ binding site [chemical binding]; other site
1034807006503	Switch I region; other site
1034807006504	G2 box; other site
1034807006505	Switch II region; other site
1034807006506	G3 box; other site
1034807006507	G4 box; other site
1034807006508	G5 box; other site
1034807006509	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1034807006510	G1 box; other site
1034807006511	GTP/Mg2+ binding site [chemical binding]; other site
1034807006512	Switch I region; other site
1034807006513	G2 box; other site
1034807006514	G3 box; other site
1034807006515	Switch II region; other site
1034807006516	G4 box; other site
1034807006517	G5 box; other site
1034807006518	Fibrobacter succinogenes major domain (Fib_succ_major); Region: Fib_succ_major; cl09821
1034807006519	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
1034807006520	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1034807006521	YARHG domain; Region: YARHG; pfam13308
1034807006522	AAA-like domain; Region: AAA_10; pfam12846
1034807006523	Zonular occludens toxin (Zot); Region: Zot; cl17485
1034807006524	CRISPR-associated protein Cpf1, subtype PREFRAN; Region: cas_Cpf1; TIGR04330
1034807006525	CRISPR spacer
1034807006526	CRISPR spacer
1034807006527	CRISPR spacer
1034807006528	CRISPR spacer
1034807006529	CRISPR spacer
1034807006530	CRISPR spacer
1034807006531	CRISPR spacer
1034807006532	CRISPR spacer
1034807006533	CRISPR spacer
1034807006534	CRISPR spacer
1034807006535	CRISPR spacer
1034807006536	CRISPR spacer
1034807006537	CRISPR spacer
1034807006538	CRISPR spacer
1034807006539	CRISPR spacer
1034807006540	CRISPR spacer
1034807006541	CRISPR spacer
1034807006542	CRISPR spacer
1034807006543	CRISPR spacer
1034807006544	CRISPR spacer
1034807006545	CRISPR spacer
1034807006546	CRISPR spacer
1034807006547	CRISPR spacer
1034807006548	CRISPR spacer
1034807006549	CRISPR spacer
1034807006550	CRISPR spacer
1034807006551	CRISPR spacer
1034807006552	CRISPR spacer
1034807006553	CRISPR spacer
1034807006554	CRISPR spacer
1034807006555	CRISPR spacer
1034807006556	CRISPR spacer
1034807006557	CRISPR spacer
1034807006558	CRISPR spacer
1034807006559	CRISPR spacer
1034807006560	CRISPR spacer
1034807006561	CRISPR spacer
1034807006562	CRISPR spacer
1034807006563	Isopropylmalate/homocitrate/citramalate synthases [Amino acid transport and metabolism]; Region: LeuA; COG0119
1034807006564	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
1034807006565	active site
1034807006566	catalytic residues [active]
1034807006567	metal binding site [ion binding]; metal-binding site
1034807006568	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
1034807006569	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
1034807006570	substrate binding site [chemical binding]; other site
1034807006571	ligand binding site [chemical binding]; other site
1034807006572	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
1034807006573	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
1034807006574	substrate binding site [chemical binding]; other site
1034807006575	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
1034807006576	tartrate dehydrogenase; Region: TTC; TIGR02089
1034807006577	Protein of unknown function (DUF1761); Region: DUF1761; pfam08570
1034807006578	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
1034807006579	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1034807006580	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1034807006581	Starch-binding associating with outer membrane; Region: SusD-like_2; pfam12771
1034807006582	starch binding outer membrane protein SusD; Region: SusD; cl17845
1034807006583	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
1034807006584	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1034807006585	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1034807006586	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1034807006587	Outer membrane protein/protective antigen OMA87 [Cell envelope biogenesis, outer membrane]; Region: COG4775
1034807006588	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1034807006589	S17 interaction site [polypeptide binding]; other site
1034807006590	S8 interaction site; other site
1034807006591	16S rRNA interaction site [nucleotide binding]; other site
1034807006592	streptomycin interaction site [chemical binding]; other site
1034807006593	23S rRNA interaction site [nucleotide binding]; other site
1034807006594	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1034807006595	30S ribosomal protein S7; Validated; Region: PRK05302
1034807006596	elongation factor G; Reviewed; Region: PRK12739
1034807006597	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1034807006598	G1 box; other site
1034807006599	putative GEF interaction site [polypeptide binding]; other site
1034807006600	GTP/Mg2+ binding site [chemical binding]; other site
1034807006601	Switch I region; other site
1034807006602	G2 box; other site
1034807006603	G3 box; other site
1034807006604	Switch II region; other site
1034807006605	G4 box; other site
1034807006606	G5 box; other site
1034807006607	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1034807006608	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1034807006609	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1034807006610	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1034807006611	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain putative pyrophosphatase YpjD from Bacillus subtilis and its bacterial homologs; Region: NTP-PPase_BsYpjD; cd11531
1034807006612	homodimer interface [polypeptide binding]; other site
1034807006613	metal binding site [ion binding]; metal-binding site
1034807006614	Domain of Unknown Function with PDB structure (DUF3857); Region: DUF3857; pfam12969
1034807006615	Domain of Unknown Function with PDB structure (DUF3857); Region: DUF3857; pfam12969
1034807006616	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
1034807006617	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
1034807006618	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
1034807006619	Homocysteine S-methyltransferase; Region: S-methyl_trans; pfam02574
1034807006620	four helix bundle protein; Region: TIGR02436
1034807006621	S23 ribosomal protein; Region: Ribosomal_S23p; pfam05635
1034807006622	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
1034807006623	substrate binding pocket [chemical binding]; other site
1034807006624	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
1034807006625	Domain of unknown function, appears to be related to a diverse group of endonucleases; Region: Endonuclease_DUF559; cd01038
1034807006626	putative active site [active]
1034807006627	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
1034807006628	B12 binding site [chemical binding]; other site
1034807006629	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
1034807006630	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
1034807006631	FAD binding site [chemical binding]; other site
1034807006632	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
1034807006633	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
1034807006634	Ca binding site [ion binding]; other site
1034807006635	active site
1034807006636	catalytic site [active]
1034807006637	Glycoside hydrolase 97; Region: Glyco_hydro_97; pfam10566
1034807006638	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
1034807006639	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1034807006640	Bestrophin, RFP-TM, chloride channel; Region: Bestrophin; cl01544
1034807006641	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
1034807006642	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1034807006643	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1034807006644	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) [Coenzyme metabolism]; Region: CysG; COG1648
1034807006645	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
1034807006646	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
1034807006647	diphthine synthase; Region: dph5; TIGR00522
1034807006648	active site
1034807006649	SAM binding site [chemical binding]; other site
1034807006650	homodimer interface [polypeptide binding]; other site
1034807006651	Sulfite reductase, beta subunit (hemoprotein) [Inorganic ion transport and metabolism]; Region: CysI; COG0155
1034807006652	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1034807006653	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1034807006654	HEPN domain; Region: HEPN; pfam05168
1034807006655	GTPases - Sulfate adenylate transferase subunit 1 [Inorganic ion transport and metabolism]; Region: CysN; COG2895
1034807006656	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
1034807006657	CysD dimerization site [polypeptide binding]; other site
1034807006658	G1 box; other site
1034807006659	putative GEF interaction site [polypeptide binding]; other site
1034807006660	GTP/Mg2+ binding site [chemical binding]; other site
1034807006661	Switch I region; other site
1034807006662	G2 box; other site
1034807006663	G3 box; other site
1034807006664	Switch II region; other site
1034807006665	G4 box; other site
1034807006666	G5 box; other site
1034807006667	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
1034807006668	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
1034807006669	Protein of unknown function (DUF2490); Region: DUF2490; pfam10677
1034807006670	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
1034807006671	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1034807006672	Active Sites [active]
1034807006673	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
1034807006674	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1034807006675	Active Sites [active]
1034807006676	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1034807006677	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1034807006678	alpha/beta hydrolase fold; Region: Abhydrolase_1; pfam00561
1034807006679	Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303
1034807006680	catalytic site [active]
1034807006681	Agmatinase and related proteins; Region: Agmatinase-like_2; cd11593
1034807006682	agmatinase; Region: agmatinase; TIGR01230
1034807006683	putative active site [active]
1034807006684	Mn binding site [ion binding]; other site
1034807006685	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
1034807006686	putative active site [active]
1034807006687	dimerization interface [polypeptide binding]; other site
1034807006688	putative tRNAtyr binding site [nucleotide binding]; other site
1034807006689	GTPase RsgA; Reviewed; Region: PRK00098
1034807006690	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
1034807006691	RNA binding site [nucleotide binding]; other site
1034807006692	homodimer interface [polypeptide binding]; other site
1034807006693	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
1034807006694	GTPase/Zn-binding domain interface [polypeptide binding]; other site
1034807006695	GTP/Mg2+ binding site [chemical binding]; other site
1034807006696	G4 box; other site
1034807006697	G5 box; other site
1034807006698	G1 box; other site
1034807006699	Switch I region; other site
1034807006700	G2 box; other site
1034807006701	G3 box; other site
1034807006702	Switch II region; other site
1034807006703	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034807006704	Coenzyme A binding pocket [chemical binding]; other site
1034807006705	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1034807006706	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034807006707	Coenzyme A binding pocket [chemical binding]; other site
1034807006708	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; cl17225
1034807006709	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1034807006710	Chorismate mutase type II; Region: CM_2; smart00830
1034807006711	prephenate dehydrogenase; Validated; Region: PRK08507
1034807006712	Prephenate dehydrogenase [Amino acid transport and metabolism]; Region: TyrA; COG0287
1034807006713	LL-diaminopimelate aminotransferase; Provisional; Region: PRK09276
1034807006714	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1034807006715	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034807006716	homodimer interface [polypeptide binding]; other site
1034807006717	catalytic residue [active]
1034807006718	Prephenate dehydratase [Amino acid transport and metabolism]; Region: PheA; COG0077
1034807006719	Prephenate dehydratase; Region: PDT; pfam00800
1034807006720	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
1034807006721	putative L-Phe binding site [chemical binding]; other site
1034807006722	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1034807006723	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
1034807006724	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
1034807006725	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1034807006726	Catalytic site [active]
1034807006727	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
1034807006728	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
1034807006729	active site
1034807006730	DNA binding site [nucleotide binding]
1034807006731	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
1034807006732	Uncharacterized ACR, COG2135; Region: DUF159; pfam02586
1034807006733	Predicted nucleotidyltransferase; Region: Nuc-transf; cl01417
1034807006734	AAA domain; Region: AAA_14; pfam13173
1034807006735	Domain of unknown function (DUF4143); Region: DUF4143; pfam13635
1034807006736	Predicted nucleotidyltransferase; Region: Nuc-transf; pfam10127
1034807006737	Uncharacterized protein family UPF0027; Region: UPF0027; cl17455
1034807006738	HipA N-terminal domain; Region: Couple_hipA; cl11853
1034807006739	HipA-like N-terminal domain; Region: HipA_N; pfam07805
1034807006740	HipA-like C-terminal domain; Region: HipA_C; pfam07804
1034807006741	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
1034807006742	salt bridge; other site
1034807006743	non-specific DNA binding site [nucleotide binding]; other site
1034807006744	sequence-specific DNA binding site [nucleotide binding]; other site
1034807006745	Rhamnogalacturan_acetylesterase_like subgroup of SGNH-hydrolases. Rhamnogalacturan acetylesterase removes acetyl esters from rhamnogalacturonan substrates, and renders them susceptible to degradation by rhamnogalacturonases. Rhamnogalacturonans are...; Region: Rhamnogalacturan_acetylesterase_like; cd01821
1034807006746	active site
1034807006747	catalytic triad [active]
1034807006748	Pectinesterase; Region: Pectinesterase; pfam01095
1034807006749	putative pectinesterase; Region: PLN02432; cl01911
1034807006750	Esterases and lipases (includes fungal lipases, cholinesterases, etc.)  These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cd00312
1034807006751	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1034807006752	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1034807006753	Pectic acid lyase; Region: Pec_lyase; pfam09492
1034807006754	Predicted unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins [General function prediction only]; Region: COG4225
1034807006755	Starch-binding associating with outer membrane; Region: SusD-like_3; pfam14322
1034807006756	SusD family; Region: SusD; pfam07980
1034807006757	TonB-linked outer membrane protein, SusC/RagA family; Region: OMP_RagA_SusC; TIGR04056
1034807006758	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1034807006759	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1034807006760	Probable polygalacturonase At3g15720; Region: PLN03003; cl14103
1034807006761	Glycosyl hydrolases family 28; Region: Glyco_hydro_28; pfam00295
1034807006762	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1034807006763	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1034807006764	DNA binding site [nucleotide binding]
1034807006765	domain linker motif; other site
1034807006766	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1034807006767	dimerization interface [polypeptide binding]; other site
1034807006768	ligand binding site [chemical binding]; other site
1034807006769	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
1034807006770	galactarate dehydratase; Region: galactar-dH20; TIGR03248
1034807006771	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1034807006772	altronate oxidoreductase; Provisional; Region: PRK03643
1034807006773	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1034807006774	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1034807006775	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1034807006776	NAD(P) binding site [chemical binding]; other site
1034807006777	active site
1034807006778	2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; Region: Eda; COG0800
1034807006779	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
1034807006780	active site
1034807006781	intersubunit interface [polypeptide binding]; other site
1034807006782	catalytic residue [active]
1034807006783	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1034807006784	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
1034807006785	substrate binding site [chemical binding]; other site
1034807006786	ATP binding site [chemical binding]; other site
1034807006787	Glucuronate isomerase; Region: UxaC; pfam02614
1034807006788	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
1034807006789	gluconate 5-dehydrogenase; Provisional; Region: PRK07097
1034807006790	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
1034807006791	NADP binding site [chemical binding]; other site
1034807006792	homodimer interface [polypeptide binding]; other site
1034807006793	active site
1034807006794	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
1034807006795	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1034807006796	putative substrate translocation pore; other site
1034807006797	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
1034807006798	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1034807006799	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4339
1034807006800	WYL domain; Region: WYL; pfam13280
1034807006801	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
1034807006802	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
1034807006803	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1034807006804	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034807006805	Coenzyme A binding pocket [chemical binding]; other site
1034807006806	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2989
1034807006807	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1034807006808	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1034807006809	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1034807006810	3-oxoacyl-(acyl-carrier-protein) synthase [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: FabB; COG0304
1034807006811	Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the...; Region: cond_enzymes; cl09938
1034807006812	active site
1034807006813	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1034807006814	adenosylmethionine-8-amino-7-oxononanoate transaminase; Region: bioA; TIGR00508
1034807006815	inhibitor-cofactor binding pocket; inhibition site
1034807006816	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1034807006817	catalytic residue [active]
1034807006818	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
1034807006819	AAA domain; Region: AAA_26; pfam13500
1034807006820	Domain of unknown function (DUF4407); Region: DUF4407; pfam14362
1034807006821	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1034807006822	RNA polymerase sigma factor RpoD, C-terminal domain; Region: RpoD_Cterm; TIGR02393
1034807006823	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1034807006824	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1034807006825	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1034807006826	DNA binding residues [nucleotide binding]
1034807006827	Protein of unknown function (DUF2813); Region: DUF2813; pfam11398
1034807006828	AAA ATPase domain; Region: AAA_15; pfam13175
1034807006829	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034807006830	Walker B; other site
1034807006831	D-loop; other site
1034807006832	H-loop/switch region; other site
1034807006833	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
1034807006834	putative active site [active]
1034807006835	putative metal-binding site [ion binding]; other site
1034807006836	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
1034807006837	Part of AAA domain; Region: AAA_19; pfam13245
1034807006838	Family description; Region: UvrD_C_2; pfam13538
1034807006839	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
1034807006840	Deoxyhypusine synthase; Region: DS; cl00826
1034807006841	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
1034807006842	DNA methylase; Region: N6_N4_Mtase; pfam01555
1034807006843	DNA methylase; Region: N6_N4_Mtase; pfam01555
1034807006844	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
1034807006845	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1034807006846	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
1034807006847	Dolichol kinase [Lipid metabolism]; Region: SEC59; COG0170
1034807006848	Domain of unknown function (DUF4276); Region: DUF4276; pfam14103
1034807006849	Predicted ATPase [General function prediction only]; Region: COG4637
1034807006850	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034807006851	Walker A/P-loop; other site
1034807006852	ATP binding site [chemical binding]; other site
1034807006853	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034807006854	ABC transporter signature motif; other site
1034807006855	Walker B; other site
1034807006856	D-loop; other site
1034807006857	H-loop/switch region; other site
1034807006858	GTP-binding protein LepA; Provisional; Region: PRK05433
1034807006859	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1034807006860	G1 box; other site
1034807006861	putative GEF interaction site [polypeptide binding]; other site
1034807006862	GTP/Mg2+ binding site [chemical binding]; other site
1034807006863	Switch I region; other site
1034807006864	G2 box; other site
1034807006865	G3 box; other site
1034807006866	Switch II region; other site
1034807006867	G4 box; other site
1034807006868	G5 box; other site
1034807006869	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1034807006870	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1034807006871	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1034807006872	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034807006873	cell division ATP-binding protein FtsE; Region: FtsE; TIGR02673
1034807006874	Walker A/P-loop; other site
1034807006875	ATP binding site [chemical binding]; other site
1034807006876	Q-loop/lid; other site
1034807006877	ABC transporter signature motif; other site
1034807006878	Walker B; other site
1034807006879	D-loop; other site
1034807006880	H-loop/switch region; other site
1034807006881	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
1034807006882	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1034807006883	putative DNA binding site [nucleotide binding]; other site
1034807006884	putative Zn2+ binding site [ion binding]; other site
1034807006885	AsnC family; Region: AsnC_trans_reg; pfam01037
1034807006886	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
1034807006887	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
1034807006888	hexamer interface [polypeptide binding]; other site
1034807006889	ligand binding site [chemical binding]; other site
1034807006890	putative active site [active]
1034807006891	NAD(P) binding site [chemical binding]; other site
1034807006892	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1034807006893	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
1034807006894	hinge; other site
1034807006895	active site
1034807006896	Agmatinase and related proteins; Region: Agmatinase-like_2; cd11593
1034807006897	putative active site [active]
1034807006898	Mn binding site [ion binding]; other site
1034807006899	Ammonia permease [Inorganic ion transport and metabolism]; Region: AmtB; COG0004
1034807006900	recombinase A; Provisional; Region: recA; PRK09354
1034807006901	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1034807006902	hexamer interface [polypeptide binding]; other site
1034807006903	Walker A motif; other site
1034807006904	ATP binding site [chemical binding]; other site
1034807006905	Walker B motif; other site
1034807006906	RecX family; Region: RecX; pfam02631
1034807006907	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1034807006908	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1034807006909	FtsX-like permease family; Region: FtsX; pfam02687
1034807006910	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1034807006911	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1034807006912	ligand binding site [chemical binding]; other site
1034807006913	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807006914	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
1034807006915	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
1034807006916	putative dimer interface [polypeptide binding]; other site
1034807006917	putative anticodon binding site; other site
1034807006918	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
1034807006919	homodimer interface [polypeptide binding]; other site
1034807006920	motif 1; other site
1034807006921	motif 2; other site
1034807006922	active site
1034807006923	motif 3; other site
1034807006924	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
1034807006925	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
1034807006926	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
1034807006927	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
1034807006928	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1034807006929	LytTr DNA-binding domain; Region: LytTR; smart00850
1034807006930	Saccharopine dehydrogenase; Region: Saccharop_dh; pfam03435
1034807006931	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
1034807006932	AMP binding site [chemical binding]; other site
1034807006933	metal binding site [ion binding]; metal-binding site
1034807006934	active site
1034807006935	GTPase SAR1 and related small G proteins [General function prediction only]; Region: COG1100
1034807006936	Ras-related in brain (Rab) family of small guanosine triphosphatases (GTPases); Region: Rab; cd00154
1034807006937	Rab subfamily motif 1 (RabSF1); other site
1034807006938	G1 box; other site
1034807006939	GTP/Mg2+ binding site [chemical binding]; other site
1034807006940	Rab subfamily motif 2 (RabSF2); other site
1034807006941	Switch I region; other site
1034807006942	G2 box; other site
1034807006943	effector interaction site; other site
1034807006944	GDI interaction site; other site
1034807006945	Rab family motif 1 (RabF1); other site
1034807006946	GEF interaction site [polypeptide binding]; other site
1034807006947	Rab family motif 2 (RabF2); other site
1034807006948	G3 box; other site
1034807006949	Switch II region; other site
1034807006950	Rab family motif 3 (RabF3); other site
1034807006951	Rab family motif 4 (RabF4); other site
1034807006952	Rab family motif 5 (RabF5); other site
1034807006953	Rab subfamily motif 3 (RabSF3); other site
1034807006954	G4 box; other site
1034807006955	G5 box; other site
1034807006956	Rab subfamily motif 4 (RabSF4); other site
1034807006957	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034807006958	dimer interface [polypeptide binding]; other site
1034807006959	phosphorylation site [posttranslational modification]
1034807006960	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034807006961	ATP binding site [chemical binding]; other site
1034807006962	Mg2+ binding site [ion binding]; other site
1034807006963	G-X-G motif; other site
1034807006964	Response regulator receiver domain; Region: Response_reg; pfam00072
1034807006965	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034807006966	active site
1034807006967	phosphorylation site [posttranslational modification]
1034807006968	intermolecular recognition site; other site
1034807006969	dimerization interface [polypeptide binding]; other site
1034807006970	tellurium resistance terB-like protein; Region: terB_like; cl11965
1034807006971	metal binding site [ion binding]; metal-binding site
1034807006972	HupE / UreJ protein; Region: HupE_UreJ_2; pfam13795
1034807006973	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
1034807006974	catalytic motif [active]
1034807006975	Zn binding site [ion binding]; other site
1034807006976	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
1034807006977	C-terminal peptidase (prc); Region: prc; TIGR00225
1034807006978	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1034807006979	protein binding site [polypeptide binding]; other site
1034807006980	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1034807006981	Catalytic dyad [active]
1034807006982	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1034807006983	tRNA pseudouridine(55) synthase; Region: TruB; TIGR00431
1034807006984	RNA binding site [nucleotide binding]; other site
1034807006985	active site
1034807006986	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
1034807006987	Protein of unknown function (DUF3098); Region: DUF3098; pfam11297
1034807006988	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
1034807006989	FtsX-like permease family; Region: FtsX; pfam02687
1034807006990	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1034807006991	active site
1034807006992	HIGH motif; other site
1034807006993	nucleotide binding site [chemical binding]; other site
1034807006994	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1034807006995	Domain of unknown function, appears to be related to a diverse group of endonucleases; Region: Endonuclease_DUF559; cd01038
1034807006996	putative active site [active]
1034807006997	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1034807006998	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1034807006999	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1034807007000	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1034807007001	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1034807007002	active site
1034807007003	KMSKS motif; other site
1034807007004	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1034807007005	tRNA binding surface [nucleotide binding]; other site
1034807007006	Anticodon-binding domain of tRNA; Region: Anticodon_1; pfam08264
1034807007007	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1034807007008	dimer interface [polypeptide binding]; other site
1034807007009	phosphorylation site [posttranslational modification]
1034807007010	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034807007011	ATP binding site [chemical binding]; other site
1034807007012	Mg2+ binding site [ion binding]; other site
1034807007013	G-X-G motif; other site
1034807007014	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1034807007015	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034807007016	active site
1034807007017	phosphorylation site [posttranslational modification]
1034807007018	intermolecular recognition site; other site
1034807007019	dimerization interface [polypeptide binding]; other site
1034807007020	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1034807007021	DNA binding site [nucleotide binding]
1034807007022	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807007023	A subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual...; Region: Band_7_5; cd03408
1034807007024	Domain of unknown function (DUF4339); Region: DUF4339; pfam14237
1034807007025	Protein of unknown function DUF262; Region: DUF262; pfam03235
1034807007026	Uncharacterized conserved protein [Function unknown]; Region: COG4938
1034807007027	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034807007028	Walker A/P-loop; other site
1034807007029	ATP binding site [chemical binding]; other site
1034807007030	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1034807007031	Walker B; other site
1034807007032	D-loop; other site
1034807007033	H-loop/switch region; other site
1034807007034	Protein of unknown function (DUF3696); Region: DUF3696; pfam12476
1034807007035	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1034807007036	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1034807007037	active site
1034807007038	catalytic tetrad [active]
1034807007039	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1034807007040	ligand binding site [chemical binding]; other site
1034807007041	Neisseria meningitides Nape-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Nape_like_AP-endo; cd10281
1034807007042	putative active site [active]
1034807007043	putative catalytic site [active]
1034807007044	putative DNA binding site [nucleotide binding]; other site
1034807007045	putative phosphate binding site [ion binding]; other site
1034807007046	metal binding site A [ion binding]; metal-binding site
1034807007047	putative AP binding site [nucleotide binding]; other site
1034807007048	putative metal binding site B [ion binding]; other site
1034807007049	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ACT14924; Region: LPLAT_ACT14924-like; cd07986
1034807007050	putative acyl-acceptor binding pocket; other site
1034807007051	Acetyltransferase (GNAT) domain; Region: Acetyltransf_5; pfam13444
1034807007052	Uncharacterized protein conserved in bacteria (DUF2063); Region: DUF2063; cl01262
1034807007053	hypothetical protein; Provisional; Region: PRK05409
1034807007054	Multiple antibiotic transporter [Intracellular trafficking and secretion]; Region: MarC; COG2095
1034807007055	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1034807007056	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1034807007057	Helix-turn-helix domain; Region: HTH_18; pfam12833
1034807007058	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1034807007059	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
1034807007060	Recombination protein O N terminal; Region: RecO_N; pfam11967
1034807007061	Recombination protein O C terminal; Region: RecO_C; pfam02565
1034807007062	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
1034807007063	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
1034807007064	glutamate dehydrogenase; Provisional; Region: PRK09414
1034807007065	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1034807007066	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
1034807007067	NAD(P) binding site [chemical binding]; other site
1034807007068	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
1034807007069	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1034807007070	active site
1034807007071	Riboflavin kinase; Region: Flavokinase; pfam01687
1034807007072	Uncharacterized ACR, YhhQ family COG1738; Region: DUF165; pfam02592
1034807007073	Domain of unknown function (DU1801); Region: DUF1801; cl17490
1034807007074	lipoprotein signal peptidase; Provisional; Region: PRK14787
1034807007075	lipoprotein signal peptidase; Provisional; Region: PRK14788
1034807007076	Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; cl00755
1034807007077	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK06039
1034807007078	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1034807007079	active site
1034807007080	HIGH motif; other site
1034807007081	nucleotide binding site [chemical binding]; other site
1034807007082	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1034807007083	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1034807007084	active site
1034807007085	KMSKS motif; other site
1034807007086	Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_ABEc; cd07961
1034807007087	tRNA binding surface [nucleotide binding]; other site
1034807007088	anticodon binding site; other site
1034807007089	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1034807007090	gamma subunit interface [polypeptide binding]; other site
1034807007091	LBP interface [polypeptide binding]; other site
1034807007092	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1034807007093	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1034807007094	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1034807007095	alpha subunit interaction interface [polypeptide binding]; other site
1034807007096	Walker A motif; other site
1034807007097	ATP binding site [chemical binding]; other site
1034807007098	Walker B motif; other site
1034807007099	inhibitor binding site; inhibition site
1034807007100	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1034807007101	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1034807007102	catalytic triad [active]
1034807007103	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1034807007104	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1034807007105	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1034807007106	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1034807007107	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
1034807007108	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1034807007109	glutaminase active site [active]
1034807007110	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1034807007111	dimer interface [polypeptide binding]; other site
1034807007112	active site
1034807007113	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1034807007114	dimer interface [polypeptide binding]; other site
1034807007115	active site
1034807007116	Domain of unknown function (DUF4270); Region: DUF4270; pfam14092
1034807007117	Starch synthase catalytic domain; Region: Glyco_transf_5; pfam08323
1034807007118	Uncharacterized protein family UPF0102; Region: UPF0102; cl00516
1034807007119	Protein of unknown function (DUF2752); Region: DUF2752; pfam10825
1034807007120	Domain of unknown function (DUF4234); Region: DUF4234; pfam14018
1034807007121	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
1034807007122	Putative D-isomer specific 2-hydroxyacid dehydrogenases, NAD-binding and catalytic domains; Region: 2-Hacid_dh_14; cd12179
1034807007123	putative ligand binding site [chemical binding]; other site
1034807007124	putative NAD binding site [chemical binding]; other site
1034807007125	catalytic site [active]
1034807007126	Peptidase M1 family Aminopeptidase N; Region: M1_APN_4; cd09603
1034807007127	Zn binding site [ion binding]; other site
1034807007128	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807007129	RIP metalloprotease RseP; Region: TIGR00054
1034807007130	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1034807007131	active site
1034807007132	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
1034807007133	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1034807007134	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1034807007135	putative substrate binding region [chemical binding]; other site
1034807007136	Protein of unknown function (DUF877); Region: DUF877; pfam05943
1034807007137	Protein of unknown function (DUF770); Region: DUF770; cl01402
1034807007138	Gene 25-like lysozyme; Region: GPW_gp25; pfam04965
1034807007139	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
1034807007140	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034807007141	Walker A motif; other site
1034807007142	ATP binding site [chemical binding]; other site
1034807007143	Walker B motif; other site
1034807007144	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1034807007145	Walker A motif; other site
1034807007146	ATP binding site [chemical binding]; other site
1034807007147	Walker B motif; other site
1034807007148	arginine finger; other site
1034807007149	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1034807007150	Domain of unknown function (DUF4280); Region: DUF4280; pfam14107
1034807007151	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
1034807007152	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08332
1034807007153	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
1034807007154	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cl17457
1034807007155	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
1034807007156	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
1034807007157	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1034807007158	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1034807007159	Transposase; Region: HTH_Tnp_1; cl17663
1034807007160	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1034807007161	Rhs element Vgr protein; Region: vgr_GE; TIGR01646
1034807007162	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1034807007163	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1034807007164	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1034807007165	Domain of unknown function (DUF4284); Region: DUF4284; pfam14112
1034807007166	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1034807007167	Domain of unknown function (DUF4303); Region: DUF4303; pfam14136
1034807007168	Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954
1034807007169	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
1034807007170	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
1034807007171	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
1034807007172	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
1034807007173	Transposase; Region: DDE_Tnp_ISL3; pfam01610
1034807007174	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
1034807007175	SMI1 / KNR4 family; Region: SMI1_KNR4; smart00860
1034807007176	HEAT repeats; Region: HEAT_2; pfam13646
1034807007177	Domain of unknown function (DUF4304); Region: DUF4304; pfam14137
1034807007178	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
1034807007179	Bacterial Ig-like domain; Region: Big_5; pfam13205
1034807007180	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1034807007181	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1034807007182	Coenzyme A binding pocket [chemical binding]; other site
1034807007183	WGR domain of bacterial DNA ligases; Region: WGR_DNA_ligase; cd07998
1034807007184	Reverse transcriptase (RNA-dependent DNA polymerase); Region: RVT_1; pfam00078
1034807007185	RT_Bac_retron_II: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_II; cd03487
1034807007186	putative active site [active]
1034807007187	putative NTP binding site [chemical binding]; other site
1034807007188	putative nucleic acid binding site [nucleotide binding]; other site
1034807007189	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1034807007190	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
1034807007191	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1034807007192	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1034807007193	ligand binding site [chemical binding]; other site
1034807007194	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
1034807007195	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1034807007196	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
1034807007197	ATP-grasp domain; Region: ATP-grasp; pfam02222
1034807007198	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1034807007199	Peptidase family U32; Region: Peptidase_U32; pfam01136
1034807007200	Collagenase; Region: DUF3656; pfam12392
1034807007201	Domain of Unknown Function with PDB structure (DUF3857); Region: DUF3857; pfam12969
1034807007202	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
1034807007203	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1034807007204	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1034807007205	glycyl-tRNA synthetase; Provisional; Region: PRK04173
1034807007206	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1034807007207	motif 1; other site
1034807007208	Glycyl-tRNA synthetase (GlyRS)-like class II core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes. It is responsible for the attachment of glycine to the 3...; Region: GlyRS-like_core; cd00774
1034807007209	active site
1034807007210	motif 2; other site
1034807007211	motif 3; other site
1034807007212	GlyRS Glycyl-anticodon binding domain. GlyRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: GlyRS_anticodon; cd00858
1034807007213	anticodon binding site; other site
1034807007214	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
1034807007215	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1034807007216	active site
1034807007217	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
1034807007218	Beta-lactamase; Region: Beta-lactamase; pfam00144
1034807007219	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
1034807007220	hydroxyglutarate oxidase; Provisional; Region: PRK11728
1034807007221	Transglycosylase; Region: Transgly; cl17702
1034807007222	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1034807007223	TonB dependent receptor; Region: TonB_dep_Rec; pfam00593
1034807007224	GLPGLI family protein; Region: GLPGLI; TIGR01200
1034807007225	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1034807007226	GLPGLI family protein; Region: GLPGLI; TIGR01200
1034807007227	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034807007228	sequence-specific DNA binding site [nucleotide binding]; other site
1034807007229	salt bridge; other site
1034807007230	biotin synthase; Region: bioB; TIGR00433
1034807007231	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1034807007232	FeS/SAM binding site; other site
1034807007233	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
1034807007234	TPR repeat; Region: TPR_11; pfam13414
1034807007235	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034807007236	binding surface
1034807007237	TPR motif; other site
1034807007238	Oxygen tolerance; Region: BatD; pfam13584
1034807007239	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034807007240	binding surface
1034807007241	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1034807007242	TPR motif; other site
1034807007243	Aerotolerance regulator N-terminal; Region: BatA; pfam07584
1034807007244	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
1034807007245	metal ion-dependent adhesion site (MIDAS); other site
1034807007246	VWA BatA type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_BatA_type; cd01467
1034807007247	metal ion-dependent adhesion site (MIDAS); other site
1034807007248	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
1034807007249	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
1034807007250	metal ion-dependent adhesion site (MIDAS); other site
1034807007251	MoxR-like ATPases [General function prediction only]; Region: COG0714
1034807007252	ATPase family associated with various cellular activities (AAA); Region: AAA_3; pfam07726
1034807007253	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1034807007254	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1034807007255	active site
1034807007256	catalytic tetrad [active]
1034807007257	Helix-turn-helix domain; Region: HTH_18; pfam12833
1034807007258	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
1034807007259	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
1034807007260	Probable Catalytic site; other site
1034807007261	metal-binding site
1034807007262	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N_2; pfam13588
1034807007263	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1034807007264	DNA polymerase III, delta subunit; Region: holA; TIGR01128
1034807007265	Domain of unknown function (DUF3127); Region: DUF3127; pfam11325
1034807007266	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
1034807007267	Eco47II restriction endonuclease; Region: RE_Eco47II; pfam09553
1034807007268	Helix-Turn-Helix DNA binding domain of truncated MerR-like proteins; Region: HTH_MerR-trunc; cd04762
1034807007269	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1034807007270	DNA binding residues [nucleotide binding]
1034807007271	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1034807007272	C-5 cytosine-specific DNA methylase; Region: DNA_methylase; pfam00145
1034807007273	cofactor binding site; other site
1034807007274	DNA binding site [nucleotide binding]
1034807007275	substrate interaction site [chemical binding]; other site
1034807007276	Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: STE14; COG2020
1034807007277	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA; cl00391
1034807007278	active site clefts [active]
1034807007279	zinc binding site [ion binding]; other site
1034807007280	dimer interface [polypeptide binding]; other site
1034807007281	Protein of unknown function (DUF3365); Region: DUF3365; pfam11845
1034807007282	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
1034807007283	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
1034807007284	heme binding site [chemical binding]; other site
1034807007285	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
1034807007286	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1034807007287	catalytic residues [active]
1034807007288	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
1034807007289	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1034807007290	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1034807007291	isocitrate dehydrogenase; Validated; Region: PRK08299
1034807007292	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1034807007293	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1034807007294	non-specific DNA binding site [nucleotide binding]; other site
1034807007295	salt bridge; other site
1034807007296	sequence-specific DNA binding site [nucleotide binding]; other site
1034807007297	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1034807007298	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1034807007299	Flagellar motor protein [Cell motility and secretion]; Region: MotB; COG1360
1034807007300	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1034807007301	ligand binding site [chemical binding]; other site
1034807007302	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1034807007303	putative nucleotide binding site [chemical binding]; other site
1034807007304	uridine monophosphate binding site [chemical binding]; other site
1034807007305	homohexameric interface [polypeptide binding]; other site
1034807007306	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1034807007307	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1034807007308	hinge region; other site
1034807007309	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
1034807007310	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
1034807007311	NADP binding site [chemical binding]; other site
1034807007312	active site
1034807007313	putative substrate binding site [chemical binding]; other site
1034807007314	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
1034807007315	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
1034807007316	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
1034807007317	substrate binding site; other site
1034807007318	tetramer interface; other site
1034807007319	phosphoprotein phosphatases of the metallophosphatase superfamily, metallophosphatase domain; Region: MPP_PPP_family; cd00144
1034807007320	active site
1034807007321	metal binding site [ion binding]; metal-binding site
1034807007322	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1034807007323	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
1034807007324	substrate binding site [chemical binding]; other site
1034807007325	ATP binding site [chemical binding]; other site
1034807007326	Outer membrane protein beta-barrel domain; Region: OMP_b-brl_2; pfam13568
1034807007327	Glutamine phosphoribosylpyrophosphate amidotransferase [Nucleotide transport and metabolism]; Region: PurF; COG0034
1034807007328	Glutamine amidotransferases class-II (GATase). The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, glutamine is hydrolyzed to glutamic acid and ammonia. This domain is related to...; Region: Gn_AT_II; cl00319
1034807007329	active site
1034807007330	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1034807007331	active site
1034807007332	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
1034807007333	LytTr DNA-binding domain; Region: LytTR; smart00850
1034807007334	Family description; Region: ACT_7; pfam13840
1034807007335	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
1034807007336	DNA repair protein RadA; Provisional; Region: PRK11823
1034807007337	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
1034807007338	Walker A motif/ATP binding site; other site
1034807007339	ATP binding site [chemical binding]; other site
1034807007340	Walker B motif; other site
1034807007341	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1034807007342	Predicted methyltransferases [General function prediction only]; Region: COG0313
1034807007343	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1034807007344	putative SAM binding site [chemical binding]; other site
1034807007345	putative homodimer interface [polypeptide binding]; other site
1034807007346	HopJ type III effector protein; Region: HopJ; pfam08888
1034807007347	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
1034807007348	DHH family; Region: DHH; pfam01368
1034807007349	DHHA1 domain; Region: DHHA1; pfam02272
1034807007350	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GpsA; COG0240
1034807007351	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1034807007352	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1034807007353	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
1034807007354	Transposase; Region: DDE_Tnp_ISL3; pfam01610
1034807007355	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464
1034807007356	Coenzyme F390 synthetase [Coenzyme metabolism]; Region: PaaK; COG1541
1034807007357	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1034807007358	AMP binding site [chemical binding]; other site
1034807007359	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
1034807007360	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1034807007361	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
1034807007362	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1034807007363	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1034807007364	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1034807007365	catalytic site [active]
1034807007366	G-X2-G-X-G-K; other site
1034807007367	hypothetical protein; Provisional; Region: PRK11820
1034807007368	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
1034807007369	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
1034807007370	Aminopeptidase P, N-terminal domain; Region: AMP_N; smart01011
1034807007371	proline aminopeptidase P II; Provisional; Region: PRK10879
1034807007372	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1034807007373	active site
1034807007374	thiamine-monophosphate kinase; Region: thiL; TIGR01379
1034807007375	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
1034807007376	ATP binding site [chemical binding]; other site
1034807007377	dimerization interface [polypeptide binding]; other site
1034807007378	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1034807007379	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
1034807007380	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
1034807007381	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1034807007382	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1034807007383	S-adenosylmethionine binding site [chemical binding]; other site
1034807007384	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
1034807007385	Ligand binding site; other site
1034807007386	Putative Catalytic site; other site
1034807007387	DXD motif; other site
1034807007388	methyltransferase, FkbM family; Region: fkbM_fam; TIGR01444
1034807007389	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1034807007390	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
1034807007391	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cl04270
1034807007392	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1034807007393	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1034807007394	active site
1034807007395	phosphorylation site [posttranslational modification]
1034807007396	intermolecular recognition site; other site
1034807007397	dimerization interface [polypeptide binding]; other site
1034807007398	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1034807007399	DNA binding residues [nucleotide binding]
1034807007400	dimerization interface [polypeptide binding]; other site
1034807007401	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
1034807007402	Histidine kinase; Region: HisKA_3; pfam07730
1034807007403	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1034807007404	ATP binding site [chemical binding]; other site
1034807007405	Mg2+ binding site [ion binding]; other site
1034807007406	G-X-G motif; other site
1034807007407	Por secretion system C-terminal sorting domain; Region: Por_Secre_tail; TIGR04183
1034807007408	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
1034807007409	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
1034807007410	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
1034807007411	NADP binding site [chemical binding]; other site
1034807007412	active site
1034807007413	putative substrate binding site [chemical binding]; other site
1034807007414	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
1034807007415	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
1034807007416	NADP-binding site; other site
1034807007417	homotetramer interface [polypeptide binding]; other site
1034807007418	substrate binding site [chemical binding]; other site
1034807007419	homodimer interface [polypeptide binding]; other site
1034807007420	active site
1034807007421	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1034807007422	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1034807007423	catalytic residues [active]
1034807007424	Fibrobacter succinogenes major domain (Fib_succ_major); Region: Fib_succ_major; cl09821
1034807007425	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1034807007426	TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783
1034807007427	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1034807007428	N-terminal plug; other site
1034807007429	ligand-binding site [chemical binding]; other site
1034807007430	PepSY-associated TM helix; Region: PepSY_TM_1; pfam13172
1034807007431	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3295
1034807007432	Cna protein B-type domain; Region: Cna_B_2; pfam13715
1034807007433	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1034807007434	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1034807007435	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1034807007436	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
1034807007437	putative active site [active]
1034807007438	catalytic triad [active]
1034807007439	dimer interface [polypeptide binding]; other site
1034807007440	multimer interface [polypeptide binding]; other site
1034807007441	Protein of unknown function (DUF3078); Region: DUF3078; pfam11276
1034807007442	Protein of unknown function (DUF2480); Region: DUF2480; pfam10652
1034807007443	FeS assembly SUF system protein; Region: SUF_assoc; TIGR02945
1034807007444	Fe-S metabolism associated domain; Region: SufE; cl00951
1034807007445	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1034807007446	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1034807007447	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1034807007448	catalytic residue [active]
1034807007449	N-terminal domain of unknown function (DUF4140); Region: DUF4140; pfam13600
1034807007450	Domain of unknown function (DUF4139); Region: DUF4139; pfam13598
1034807007451	TonB-dependent Receptor Plug Domain; Region: Plug; pfam07715
1034807007452	Domain of unknown function (DUF4139); Region: DUF4139; pfam13598
1034807007453	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
1034807007454	MgtE intracellular N domain; Region: MgtE_N; smart00924
1034807007455	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
1034807007456	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
1034807007457	Divalent cation transporter; Region: MgtE; pfam01769
1034807007458	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1034807007459	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
1034807007460	Domain of unknown function (DUF4286); Region: DUF4286; pfam14114
1034807007461	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1034807007462	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1034807007463	binding surface
1034807007464	TPR motif; other site
1034807007465	TPR repeat; Region: TPR_11; pfam13414
1034807007466	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1034807007467	TPR motif; other site
1034807007468	binding surface
1034807007469	seryl-tRNA synthetase; Provisional; Region: PRK05431
1034807007470	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1034807007471	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1034807007472	dimer interface [polypeptide binding]; other site
1034807007473	active site
1034807007474	motif 1; other site
1034807007475	motif 2; other site
1034807007476	motif 3; other site
1034807007477	Pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]; Region: ProC; COG0345
1034807007478	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
1034807007479	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1034807007480	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
1034807007481	putative NAD(P) binding site [chemical binding]; other site
1034807007482	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
1034807007483	EamA-like transporter family; Region: EamA; pfam00892
1034807007484	EamA-like transporter family; Region: EamA; pfam00892
1034807007485	S-adenosyl-L-homocysteine hydrolase; Provisional; Region: PRK05476
1034807007486	S-Adenosylhomocysteine Hydrolase, NAD-binding and catalytic domains; Region: SAHH; cd00401
1034807007487	homotetramer interface [polypeptide binding]; other site
1034807007488	ligand binding site [chemical binding]; other site
1034807007489	catalytic site [active]
1034807007490	NAD binding site [chemical binding]; other site
1034807007491	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
1034807007492	geranylgeranylglyceryl phosphate synthase-like protein; Reviewed; Region: PRK04169
1034807007493	phosphate binding site [ion binding]; other site
1034807007494	Protein of unknown function (DUF2809); Region: DUF2809; pfam10990
1034807007495	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
1034807007496	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
1034807007497	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
1034807007498	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1034807007499	RNA binding site [nucleotide binding]; other site
1034807007500	Predicted flavoprotein [General function prediction only]; Region: COG0431
1034807007501	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1034807007502	DoxX-like family; Region: DoxX_2; pfam13564
1034807007503	Predicted transcriptional regulators [Transcription]; Region: COG1733
1034807007504	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1034807007505	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
1034807007506	nudix motif; other site
1034807007507	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
1034807007508	manganese transport protein MntH; Reviewed; Region: PRK00701
1034807007509	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
1034807007510	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1034807007511	Ligand Binding Site [chemical binding]; other site
1034807007512	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
1034807007513	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1034807007514	TPP-binding site; other site
1034807007515	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1034807007516	PYR/PP interface [polypeptide binding]; other site
1034807007517	dimer interface [polypeptide binding]; other site
1034807007518	TPP binding site [chemical binding]; other site
1034807007519	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1034807007520	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1034807007521	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1034807007522	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1034807007523	dimer interface [polypeptide binding]; other site
1034807007524	motif 1; other site
1034807007525	active site
1034807007526	motif 2; other site
1034807007527	motif 3; other site
1034807007528	A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194
1034807007529	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1034807007530	minor groove reading motif; other site
1034807007531	helix-hairpin-helix signature motif; other site
1034807007532	substrate binding pocket [chemical binding]; other site
1034807007533	active site
1034807007534	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576
1034807007535	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
1034807007536	DNA binding and oxoG recognition site [nucleotide binding]
1034807007537	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1034807007538	IHF - DNA interface [nucleotide binding]; other site
1034807007539	IHF dimer interface [polypeptide binding]; other site
1034807007540	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
1034807007541	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1034807007542	homodimer interface [polypeptide binding]; other site
1034807007543	oligonucleotide binding site [chemical binding]; other site
1034807007544	6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242
1034807007545	active site
1034807007546	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
1034807007547	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
1034807007548	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1034807007549	active site
1034807007550	HIGH motif; other site
1034807007551	KMSKS motif; other site
1034807007552	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1034807007553	tRNA binding surface [nucleotide binding]; other site
1034807007554	anticodon binding site; other site
1034807007555	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
1034807007556	dimer interface [polypeptide binding]; other site
1034807007557	putative tRNA-binding site [nucleotide binding]; other site
1034807007558	Ribose/Galactose Isomerase; Region: LacAB_rpiB; pfam02502
1034807007559	Initiator Replication protein; Region: Rep_3; pfam01051
1034807007560	Plasmid encoded toxin Txe; Region: Plasmid_Txe; cl17389