-- dump date 20140619_095006 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_897666.1 118496616 4547377 145..1620 1 NC_008601.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 1620 dnaA 4547377 dnaA Francisella tularensis subsp. novicida U112 chromosomal replication initiation protein YP_897666.1 145 D 401614 CDS YP_897667.1 118496617 4547378 1657..2760 1 NC_008601.1 DNA polymerase III subunit beta 2760 dnaN 4547378 dnaN Francisella tularensis subsp. novicida U112 DNA polymerase III subunit beta YP_897667.1 1657 D 401614 CDS YP_897668.1 118496618 4547379 complement(2791..4044) 1 NC_008601.1 metabolite:H+ symporter (MHS) family protein 4044 4547379 FTN_0003 Francisella tularensis subsp. novicida U112 metabolite:H+ symporter (MHS) family protein YP_897668.1 2791 R 401614 CDS YP_897669.1 118496619 4547380 4244..5767 1 NC_008601.1 aspartate/glutamate transporter 5767 4547380 FTN_0004 Francisella tularensis subsp. novicida U112 aspartate/glutamate transporter YP_897669.1 4244 D 401614 CDS YP_897670.1 118496620 4547381 5832..6803 1 NC_008601.1 divalent inorganic cation transporter 6803 corA 4547381 corA Francisella tularensis subsp. novicida U112 divalent inorganic cation transporter YP_897670.1 5832 D 401614 CDS YP_897671.1 118496621 4548498 complement(6816..7283) 1 NC_008601.1 hypothetical protein 7283 4548498 FTN_0006 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897671.1 6816 R 401614 CDS YP_897672.1 118496622 4548499 complement(7361..7678) 1 NC_008601.1 hypothetical protein 7678 4548499 FTN_0007 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897672.1 7361 R 401614 CDS YP_897673.1 118496623 4548500 complement(7768..8640) 1 NC_008601.1 drug/metabolite exporter protein 8640 4548500 FTN_0008 Francisella tularensis subsp. novicida U112 drug/metabolite exporter protein YP_897673.1 7768 R 401614 CDS YP_897674.1 118496624 4548501 8784..8966 1 NC_008601.1 hypothetical protein 8966 4548501 FTN_0009 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897674.1 8784 D 401614 CDS YP_897675.1 118496625 4548502 complement(9372..9806) 1 NC_008601.1 phage terminase small subunit 9806 4548502 FTN_0010 Francisella tularensis subsp. novicida U112 phage terminase small subunit YP_897675.1 9372 R 401614 CDS YP_897676.1 118496626 4548503 complement(10041..10220) 1 NC_008601.1 hypothetical protein 10220 4548503 FTN_0011 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897676.1 10041 R 401614 CDS YP_897677.1 118496627 4548504 complement(10217..10438) 1 NC_008601.1 hypothetical protein 10438 4548504 FTN_0012 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897677.1 10217 R 401614 CDS YP_897678.1 118496628 4548505 complement(10936..11835) 1 NC_008601.1 hypothetical protein 11835 4548505 FTN_0013 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897678.1 10936 R 401614 CDS YP_897679.1 118496629 4548506 complement(11832..12728) 1 NC_008601.1 hypothetical protein 12728 4548506 FTN_0014 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897679.1 11832 R 401614 CDS YP_897680.1 118496630 4548507 complement(12732..12911) 1 NC_008601.1 AlpA family regulatory protein 12911 4548507 FTN_0015 Francisella tularensis subsp. novicida U112 AlpA family regulatory protein YP_897680.1 12732 R 401614 CDS YP_897681.1 118496631 4548508 complement(13107..13781) 1 NC_008601.1 hypothetical protein 13781 4548508 FTN_0016 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897681.1 13107 R 401614 CDS YP_897682.1 118496632 4548509 complement(13786..15027) 1 NC_008601.1 phage integrase 15027 4548509 FTN_0017 Francisella tularensis subsp. novicida U112 phage integrase YP_897682.1 13786 R 401614 CDS YP_897683.1 118496633 4548510 complement(15685..16908) 1 NC_008601.1 serine permease 16908 sdaC 4548510 sdaC Francisella tularensis subsp. novicida U112 serine permease YP_897683.1 15685 R 401614 CDS YP_897684.1 118496634 4548511 complement(17049..17975) 1 NC_008601.1 aspartate carbamoyltransferase 17975 pyrB 4548511 pyrB Francisella tularensis subsp. novicida U112 aspartate carbamoyltransferase YP_897684.1 17049 R 401614 CDS YP_897685.1 118496635 4548512 complement(18117..21401) 1 NC_008601.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 21401 carB 4548512 carB Francisella tularensis subsp. novicida U112 carbamoyl phosphate synthase large subunit YP_897685.1 18117 R 401614 CDS YP_897686.1 118496636 4548513 complement(21406..22572) 1 NC_008601.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 22572 carA 4548513 carA Francisella tularensis subsp. novicida U112 carbamoyl phosphate synthase small subunit YP_897686.1 21406 R 401614 CDS YP_897687.1 118496637 4548514 22992..24047 1 NC_008601.1 histidine acid phosphatase 24047 4548514 FTN_0022 Francisella tularensis subsp. novicida U112 histidine acid phosphatase YP_897687.1 22992 D 401614 CDS YP_897688.1 118496638 4548515 complement(24068..24748) 1 NC_008601.1 catalyzes the S-adenosylmethionine-dependent transmethylation of thiopurine compounds; may be involved in selenium cycling by forming dimethylselenide and/or dimethyldiselenide; thiopurine S-methyltransferase 24748 tmpT 4548515 tmpT Francisella tularensis subsp. novicida U112 thiopurine S-methyltransferase YP_897688.1 24068 R 401614 CDS YP_897689.1 118496639 4548516 24880..26226 1 NC_008601.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; dihydroorotase 26226 pyrC 4548516 pyrC Francisella tularensis subsp. novicida U112 dihydroorotase YP_897689.1 24880 D 401614 CDS YP_897690.1 118496640 4548517 complement(26210..26797) 1 NC_008601.1 hypothetical protein 26797 4548517 FTN_0025 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897690.1 26210 R 401614 CDS YP_897691.1 118496641 4547493 27076..27330 1 NC_008601.1 hypothetical protein 27330 4547493 FTN_0026 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897691.1 27076 D 401614 CDS YP_897692.1 118496642 4547494 28044..28595 1 NC_008601.1 hypothetical protein 28595 4547494 FTN_0027 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897692.1 28044 D 401614 CDS YP_897693.1 118496643 4547495 complement(28711..29763) 1 NC_008601.1 hypothetical protein 29763 4547495 FTN_0028 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897693.1 28711 R 401614 CDS YP_897694.1 118496644 4547496 complement(29750..30715) 1 NC_008601.1 HlyD family membrane fusion protein 30715 4547496 FTN_0029 Francisella tularensis subsp. novicida U112 HlyD family membrane fusion protein YP_897694.1 29750 R 401614 CDS YP_897695.1 118496645 4547497 complement(30802..31209) 1 NC_008601.1 hypothetical protein 31209 4547497 FTN_0030 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897695.1 30802 R 401614 CDS YP_897696.1 118496646 4547498 31335..32204 1 NC_008601.1 LysR family transcriptional regulator 32204 4547498 FTN_0031 Francisella tularensis subsp. novicida U112 LysR family transcriptional regulator YP_897696.1 31335 D 401614 CDS YP_897697.1 118496647 4547499 complement(32205..32831) 1 NC_008601.1 hypothetical protein 32831 4547499 FTN_0032 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897697.1 32205 R 401614 CDS YP_897698.1 118496648 4547500 32974..33522 1 NC_008601.1 chorismate mutase 33522 4547500 FTN_0033 Francisella tularensis subsp. novicida U112 chorismate mutase YP_897698.1 32974 D 401614 CDS YP_897699.1 118496649 4547501 complement(33577..36951) 1 NC_008601.1 hypothetical protein 36951 4547501 FTN_0034 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897699.1 33577 R 401614 CDS YP_897700.1 118496650 4547502 37218..37862 1 NC_008601.1 orotidine-5'-phosphate decarboxylase 37862 pyrF 4547502 pyrF Francisella tularensis subsp. novicida U112 orotidine-5'-phosphate decarboxylase YP_897700.1 37218 D 401614 CDS YP_897701.1 118496651 4547503 37864..38604 1 NC_008601.1 dihydroorotate oxidase 38604 pyrD 4547503 pyrD Francisella tularensis subsp. novicida U112 dihydroorotate oxidase YP_897701.1 37864 D 401614 CDS YP_897702.1 118496652 4547504 complement(40003..40347) 1 NC_008601.1 hypothetical protein 40347 4547504 FTN_0037 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897702.1 40003 R 401614 CDS YP_897703.1 118496653 4547505 complement(40366..40650) 1 NC_008601.1 hypothetical protein 40650 4547505 FTN_0038 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897703.1 40366 R 401614 CDS YP_897704.1 118496654 4547506 complement(40653..41078) 1 NC_008601.1 hypothetical protein 41078 4547506 FTN_0039 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897704.1 40653 R 401614 CDS YP_897705.1 118496655 4547507 complement(41093..44347) 1 NC_008601.1 hypothetical protein 44347 4547507 FTN_0040 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897705.1 41093 R 401614 CDS YP_897706.1 118496656 4547508 complement(44366..46582) 1 NC_008601.1 hypothetical protein 46582 4547508 FTN_0041 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897706.1 44366 R 401614 CDS YP_897707.1 118496657 4547509 46882..47439 1 NC_008601.1 hypothetical protein 47439 4547509 FTN_0042 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897707.1 46882 D 401614 CDS YP_897708.1 118496658 4547510 47436..48968 1 NC_008601.1 hypothetical protein 48968 4547510 FTN_0043 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897708.1 47436 D 401614 CDS YP_897709.1 118496659 4548536 49002..49649 1 NC_008601.1 hypothetical protein 49649 4548536 FTN_0044 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897709.1 49002 D 401614 CDS YP_897710.1 118496660 4548537 49665..50744 1 NC_008601.1 hypothetical protein 50744 4548537 FTN_0045 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897710.1 49665 D 401614 CDS YP_897711.1 118496661 4548538 50758..53736 1 NC_008601.1 hypothetical protein 53736 4548538 FTN_0046 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897711.1 50758 D 401614 CDS YP_897712.1 118496662 4548539 53754..57530 1 NC_008601.1 hypothetical protein 57530 4548539 FTN_0047 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897712.1 53754 D 401614 CDS YP_897713.1 118496663 4548540 57540..58760 1 NC_008601.1 hypothetical protein 58760 4548540 FTN_0048 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897713.1 57540 D 401614 CDS YP_897714.1 118496664 4548541 58770..59594 1 NC_008601.1 hypothetical protein 59594 4548541 FTN_0049 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897714.1 58770 D 401614 CDS YP_897715.1 118496665 4548542 59569..61092 1 NC_008601.1 hypothetical protein 61092 4548542 FTN_0050 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897715.1 59569 D 401614 CDS YP_897716.1 118496666 4548543 61102..61710 1 NC_008601.1 hypothetical protein 61710 4548543 FTN_0051 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897716.1 61102 D 401614 CDS YP_897717.1 118496667 4548544 61717..63780 1 NC_008601.1 hypothetical protein 63780 4548544 FTN_0052 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897717.1 61717 D 401614 CDS YP_897718.1 118496668 4548545 63789..64394 1 NC_008601.1 hypothetical protein 64394 4548545 FTN_0053 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897718.1 63789 D 401614 CDS YP_897719.1 118496669 4548546 64387..64767 1 NC_008601.1 hypothetical protein 64767 4548546 FTN_0054 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897719.1 64387 D 401614 CDS YP_897720.1 118496670 4548547 complement(64847..65683) 1 NC_008601.1 prephenate dehydrogenase 65683 tyrA 4548547 tyrA Francisella tularensis subsp. novicida U112 prephenate dehydrogenase YP_897720.1 64847 R 401614 CDS YP_897721.1 118496671 4548548 complement(65951..66388) 1 NC_008601.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 66388 dtd 4548548 dtd Francisella tularensis subsp. novicida U112 D-tyrosyl-tRNA(Tyr) deacylase YP_897721.1 65951 R 401614 CDS YP_897722.1 118496672 4548549 complement(66662..67894) 1 NC_008601.1 major facilitator transporter 67894 4548549 FTN_0057 Francisella tularensis subsp. novicida U112 major facilitator transporter YP_897722.1 66662 R 401614 CDS YP_897723.1 118496673 4548550 complement(67913..69628) 1 NC_008601.1 beta-fructofuranosidase 69628 4548550 FTN_0058 Francisella tularensis subsp. novicida U112 beta-fructofuranosidase YP_897723.1 67913 R 401614 CDS YP_897724.1 118496674 4548551 complement(69704..70783) 1 NC_008601.1 3-isopropylmalate dehydrogenase 70783 leuB 4548551 leuB Francisella tularensis subsp. novicida U112 3-isopropylmalate dehydrogenase YP_897724.1 69704 R 401614 CDS YP_897725.1 118496675 4548552 complement(70785..71354) 1 NC_008601.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 71354 leuD 4548552 leuD Francisella tularensis subsp. novicida U112 isopropylmalate isomerase small subunit YP_897725.1 70785 R 401614 CDS YP_897726.1 118496676 4548553 complement(71357..72766) 1 NC_008601.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 72766 leuC 4548553 leuC Francisella tularensis subsp. novicida U112 isopropylmalate isomerase large subunit YP_897726.1 71357 R 401614 CDS YP_897727.1 118496677 4548554 complement(72768..74348) 1 NC_008601.1 2-isopropylmalate synthase 74348 leuA 4548554 leuA Francisella tularensis subsp. novicida U112 2-isopropylmalate synthase YP_897727.1 72768 R 401614 CDS YP_897728.1 118496678 4548555 complement(74359..75246) 1 NC_008601.1 branched-chain amino acid aminotransferase 75246 ilvE 4548555 ilvE Francisella tularensis subsp. novicida U112 branched-chain amino acid aminotransferase YP_897728.1 74359 R 401614 CDS YP_897729.1 118496679 4547644 complement(75645..78278) 1 NC_008601.1 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase 78278 ppdK 4547644 ppdK Francisella tularensis subsp. novicida U112 pyruvate phosphate dikinase YP_897729.1 75645 R 401614 CDS YP_897730.1 118496680 4547645 complement(78555..78869) 1 NC_008601.1 hypothetical protein 78869 4547645 FTN_0065 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897730.1 78555 R 401614 CDS YP_897731.1 118496681 4547646 complement(79068..81317) 1 NC_008601.1 ferrous iron transport protein B 81317 feoB 4547646 feoB Francisella tularensis subsp. novicida U112 ferrous iron transport protein B YP_897731.1 79068 R 401614 CDS YP_897732.1 118496682 4547647 complement(81418..82032) 1 NC_008601.1 hypothetical protein 82032 4547647 FTN_0067 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897732.1 81418 R 401614 CDS YP_897733.1 118496683 4547648 complement(82047..82583) 1 NC_008601.1 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 82583 orn 4547648 orn Francisella tularensis subsp. novicida U112 oligoribonuclease YP_897733.1 82047 R 401614 CDS YP_897734.1 118496684 4547649 complement(82586..83155) 1 NC_008601.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 83155 efp 4547649 efp Francisella tularensis subsp. novicida U112 elongation factor P YP_897734.1 82586 R 401614 CDS YP_897735.1 118496685 4547650 complement(83196..83603) 1 NC_008601.1 Type IV pili, pilus assembly protein 83603 pilE 4547650 pilE Francisella tularensis subsp. novicida U112 Type IV pili, pilus assembly protein YP_897735.1 83196 R 401614 CDS YP_897736.1 118496686 4547651 complement(83616..84539) 1 NC_008601.1 LPS fatty acid acyltransferase 84539 4547651 FTN_0071 Francisella tularensis subsp. novicida U112 LPS fatty acid acyltransferase YP_897736.1 83616 R 401614 CDS YP_897737.1 118496687 4547652 complement(84600..85499) 1 NC_008601.1 LPS fatty acid acyltransferase 85499 4547652 FTN_0072 Francisella tularensis subsp. novicida U112 LPS fatty acid acyltransferase YP_897737.1 84600 R 401614 CDS YP_897738.1 118496688 4547653 complement(85506..87161) 1 NC_008601.1 membrane protein 87161 4547653 FTN_0073 Francisella tularensis subsp. novicida U112 membrane protein YP_897738.1 85506 R 401614 CDS YP_897739.1 118496689 4547654 complement(87170..87418) 1 NC_008601.1 hypothetical protein 87418 4547654 FTN_0074 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897739.1 87170 R 401614 CDS YP_897740.1 118496690 4547655 complement(87394..87747) 1 NC_008601.1 ribonuclease P protein component 87747 rnpA 4547655 rnpA Francisella tularensis subsp. novicida U112 ribonuclease P protein component YP_897740.1 87394 R 401614 CDS YP_897741.1 118496691 4547656 complement(87737..87871) 1 NC_008601.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 87871 rpmH 4547656 rpmH Francisella tularensis subsp. novicida U112 50S ribosomal protein L34 YP_897741.1 87737 R 401614 CDS YP_897742.1 118496692 4547657 complement(87963..88421) 1 NC_008601.1 hypothetical protein 88421 4547657 FTN_0077 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897742.1 87963 R 401614 CDS YP_897743.1 118496693 4547658 88548..89321 1 NC_008601.1 shikimate 5-dehydrogenase 89321 aroE 4547658 aroE Francisella tularensis subsp. novicida U112 shikimate 5-dehydrogenase YP_897743.1 88548 D 401614 CDS YP_897744.1 118496694 4547659 89393..90748 1 NC_008601.1 UDP-N-acetylmuramate-alanine ligase 90748 murC 4547659 murC Francisella tularensis subsp. novicida U112 UDP-N-acetylmuramate-alanine ligase YP_897744.1 89393 D 401614 CDS YP_897745.1 118496695 4547660 90741..91613 1 NC_008601.1 SAM-dependent methyltransferase 91613 4547660 FTN_0080 Francisella tularensis subsp. novicida U112 SAM-dependent methyltransferase YP_897745.1 90741 D 401614 CDS YP_897746.1 118496696 4547661 complement(91624..92358) 1 NC_008601.1 hypothetical protein 92358 4547661 FTN_0081 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897746.1 91624 R 401614 CDS YP_897747.1 118496697 4547662 92435..92998 1 NC_008601.1 HAD superfamily hydrolase 92998 4547662 FTN_0082 Francisella tularensis subsp. novicida U112 HAD superfamily hydrolase YP_897747.1 92435 D 401614 CDS YP_897748.1 118496698 4548930 93070..93828 1 NC_008601.1 hypothetical protein 93828 4548930 FTN_0083 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897748.1 93070 D 401614 CDS YP_897749.1 118496699 4548931 93832..96573 1 NC_008601.1 DNA/RNA helicase 96573 4548931 FTN_0084 Francisella tularensis subsp. novicida U112 DNA/RNA helicase YP_897749.1 93832 D 401614 CDS YP_897750.1 118496700 4548932 96649..97485 1 NC_008601.1 universal stress protein 97485 uspA 4548932 uspA Francisella tularensis subsp. novicida U112 universal stress protein YP_897750.1 96649 D 401614 CDS YP_897751.1 118496701 4548933 97601..98830 1 NC_008601.1 metabolite:H+ symporter (MHS) family protein 98830 4548933 FTN_0086 Francisella tularensis subsp. novicida U112 metabolite:H+ symporter (MHS) family protein YP_897751.1 97601 D 401614 CDS YP_897752.1 118496702 4548934 98862..99479 1 NC_008601.1 allophanate hydrolase subunit 1 99479 4548934 FTN_0087 Francisella tularensis subsp. novicida U112 allophanate hydrolase subunit 1 YP_897752.1 98862 D 401614 CDS YP_897753.1 118496703 4548935 99479..100177 1 NC_008601.1 LamB/YcsF family protein 100177 4548935 FTN_0088 Francisella tularensis subsp. novicida U112 LamB/YcsF family protein YP_897753.1 99479 D 401614 CDS YP_897754.1 118496704 4548936 100182..100994 1 NC_008601.1 hydrolase subunit 100994 4548936 FTN_0089 Francisella tularensis subsp. novicida U112 hydrolase subunit YP_897754.1 100182 D 401614 CDS YP_897755.1 118496705 4548937 complement(101001..102545) 1 NC_008601.1 acid phosphatase 102545 4548937 FTN_0090 Francisella tularensis subsp. novicida U112 acid phosphatase YP_897755.1 101001 R 401614 CDS YP_897756.1 118496706 4548938 102854..103510 1 NC_008601.1 hypothetical protein 103510 4548938 FTN_0091 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897756.1 102854 D 401614 CDS YP_897757.1 118496707 4548939 103528..104523 1 NC_008601.1 inorganic phosphate transporter (PiT) family protein 104523 4548939 FTN_0092 Francisella tularensis subsp. novicida U112 inorganic phosphate transporter (PiT) family protein YP_897757.1 103528 D 401614 CDS YP_897758.1 118496708 4548940 104604..105119 1 NC_008601.1 cytochrome b561 family protein 105119 4548940 FTN_0093 Francisella tularensis subsp. novicida U112 cytochrome b561 family protein YP_897758.1 104604 D 401614 CDS YP_897759.1 118496709 4548941 complement(105126..106073) 1 NC_008601.1 LysR family transcriptional regulator 106073 4548941 FTN_0094 Francisella tularensis subsp. novicida U112 LysR family transcriptional regulator YP_897759.1 105126 R 401614 CDS YP_897760.1 118496710 4548942 complement(106142..106807) 1 NC_008601.1 nitroreductase 106807 4548942 FTN_0095 Francisella tularensis subsp. novicida U112 nitroreductase YP_897760.1 106142 R 401614 CDS YP_897761.1 118496711 4548943 107210..107902 1 NC_008601.1 hypothetical protein 107902 4548943 FTN_0096 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897761.1 107210 D 401614 CDS YP_897762.1 118496712 4548944 complement(107899..109104) 1 NC_008601.1 hydroxy/aromatic amino acid permease (HAAAP) family protein 109104 4548944 FTN_0097 Francisella tularensis subsp. novicida U112 hydroxy/aromatic amino acid permease (HAAAP) family protein YP_897762.1 107899 R 401614 CDS YP_897763.1 118496713 4548945 109204..109821 1 NC_008601.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 109821 gidB 4548945 gidB Francisella tularensis subsp. novicida U112 16S rRNA methyltransferase GidB YP_897763.1 109204 D 401614 CDS YP_897764.1 118496714 4548946 109818..110486 1 NC_008601.1 hypothetical protein 110486 4548946 FTN_0099 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897764.1 109818 D 401614 CDS YP_897765.1 118496715 4548947 complement(110479..111495) 1 NC_008601.1 hypothetical protein 111495 4548947 FTN_0100 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897765.1 110479 R 401614 CDS YP_897766.1 118496716 4548948 complement(111566..112462) 1 NC_008601.1 LysR family transcriptional regulator 112462 4548948 FTN_0101 Francisella tularensis subsp. novicida U112 LysR family transcriptional regulator YP_897766.1 111566 R 401614 CDS YP_897767.1 118496717 4548949 112565..113719 1 NC_008601.1 major facilitator transporter 113719 4548949 FTN_0102 Francisella tularensis subsp. novicida U112 major facilitator transporter YP_897767.1 112565 D 401614 CDS YP_897768.1 118496718 4547761 complement(113785..116088) 1 NC_008601.1 hypothetical protein 116088 4547761 FTN_0103 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897768.1 113785 R 401614 CDS YP_897769.1 118496719 4547762 116266..116862 1 NC_008601.1 phosphoheptose isomerase 116862 4547762 FTN_0104 Francisella tularensis subsp. novicida U112 phosphoheptose isomerase YP_897769.1 116266 D 401614 CDS YP_897770.1 118496720 4547763 116870..117226 1 NC_008601.1 outer membrane lipoprotein 117226 4547763 FTN_0105 Francisella tularensis subsp. novicida U112 outer membrane lipoprotein YP_897770.1 116870 D 401614 CDS YP_897771.1 118496721 4547764 complement(117300..117572) 1 NC_008601.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 117572 rpsT 4547764 rpsT Francisella tularensis subsp. novicida U112 30S ribosomal protein S20 YP_897771.1 117300 R 401614 CDS YP_897772.1 118496722 4547765 117842..119626 1 NC_008601.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 119626 lepA 4547765 lepA Francisella tularensis subsp. novicida U112 GTP-binding protein LepA YP_897772.1 117842 D 401614 CDS YP_897773.1 118496723 4547766 119640..120719 1 NC_008601.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 120719 mnmA 4547766 mnmA Francisella tularensis subsp. novicida U112 tRNA-specific 2-thiouridylase MnmA YP_897773.1 119640 D 401614 CDS YP_897774.1 118496724 4547767 complement(120737..121717) 1 NC_008601.1 hypothetical protein 121717 4547767 FTN_0109 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897774.1 120737 R 401614 CDS YP_897775.1 118496725 4547768 complement(121812..122336) 1 NC_008601.1 peptide deformylase 122336 4547768 FTN_0110 Francisella tularensis subsp. novicida U112 peptide deformylase YP_897775.1 121812 R 401614 CDS YP_897776.1 118496726 4547769 complement(122333..122776) 1 NC_008601.1 riboflavin synthase beta-chain 122776 ribH 4547769 ribH Francisella tularensis subsp. novicida U112 riboflavin synthase beta-chain YP_897776.1 122333 R 401614 CDS YP_897777.1 118496727 4547770 complement(122786..123997) 1 NC_008601.1 3,4-dihydroxy-2-butanone 4-phosphate synthase 123997 ribAB 4547770 ribAB Francisella tularensis subsp. novicida U112 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_897777.1 122786 R 401614 CDS YP_897778.1 118496728 4547771 complement(123990..124595) 1 NC_008601.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 124595 ribC 4547771 ribC Francisella tularensis subsp. novicida U112 riboflavin synthase subunit alpha YP_897778.1 123990 R 401614 CDS YP_897779.1 118496729 4547772 complement(124588..125655) 1 NC_008601.1 pyrimidine reductase/pyrimidine deaminase 125655 ribD 4547772 ribD Francisella tularensis subsp. novicida U112 pyrimidine reductase/pyrimidine deaminase YP_897779.1 124588 R 401614 CDS YP_897780.1 118496730 4547773 126046..127296 1 NC_008601.1 Na+/H+ antiporter 127296 4547773 FTN_0115 Francisella tularensis subsp. novicida U112 Na+/H+ antiporter YP_897780.1 126046 D 401614 CDS YP_897781.1 118496731 4547774 complement(127306..129003) 1 NC_008601.1 indolepyruvate decarboxylase 129003 ipdC 4547774 ipdC Francisella tularensis subsp. novicida U112 indolepyruvate decarboxylase YP_897781.1 127306 R 401614 CDS YP_897782.1 118496732 4547775 complement(129104..129457) 1 NC_008601.1 ferredoxin 129457 4547775 FTN_0117 Francisella tularensis subsp. novicida U112 ferredoxin YP_897782.1 129104 R 401614 CDS YP_897783.1 118496733 4547776 129531..130454 1 NC_008601.1 S49 family serine peptidase 130454 4547776 FTN_0118 Francisella tularensis subsp. novicida U112 S49 family serine peptidase YP_897783.1 129531 D 401614 CDS YP_897784.1 118496734 4547777 130544..131083 1 NC_008601.1 hypothetical protein 131083 4547777 FTN_0119 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897784.1 130544 D 401614 CDS YP_897785.1 118496735 4547778 131219..131641 1 NC_008601.1 rhodanese-related sulfurtransferase 131641 4547778 FTN_0120 Francisella tularensis subsp. novicida U112 rhodanese-related sulfurtransferase YP_897785.1 131219 D 401614 CDS YP_897786.1 118496736 4547779 131668..132117 1 NC_008601.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 132117 secB1 4547779 secB1 Francisella tularensis subsp. novicida U112 preprotein translocase subunit SecB YP_897786.1 131668 D 401614 CDS YP_897787.1 118496737 4548478 132141..133220 1 NC_008601.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 133220 recA 4548478 recA Francisella tularensis subsp. novicida U112 recombinase A YP_897787.1 132141 D 401614 CDS YP_897788.1 118496738 4548479 133207..133659 1 NC_008601.1 inhibitor of RecA 133659 recX 4548479 recX Francisella tularensis subsp. novicida U112 inhibitor of RecA YP_897788.1 133207 D 401614 CDS YP_897789.1 118496739 4548480 133833..134312 1 NC_008601.1 single-strand DNA binding protein 134312 ssb 4548480 ssb Francisella tularensis subsp. novicida U112 single-strand DNA binding protein YP_897789.1 133833 D 401614 CDS YP_897790.1 118496740 4548481 134418..135572 1 NC_008601.1 propionate kinase 2 / acetate kinase A 135572 ackA 4548481 ackA Francisella tularensis subsp. novicida U112 propionate kinase 2 / acetate kinase A YP_897790.1 134418 D 401614 CDS YP_897791.1 118496741 4548482 135582..137678 1 NC_008601.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 137678 pta 4548482 pta Francisella tularensis subsp. novicida U112 phosphate acetyltransferase YP_897791.1 135582 D 401614 CDS YP_897792.1 118496742 4548483 137693..139126 1 NC_008601.1 succinate semialdehyde dehydrogenase 139126 gabD 4548483 gabD Francisella tularensis subsp. novicida U112 succinate semialdehyde dehydrogenase YP_897792.1 137693 D 401614 CDS YP_897793.1 118496743 4548484 139163..140371 1 NC_008601.1 metabolite:H+ symporter (MHS) family protein 140371 4548484 FTN_0128 Francisella tularensis subsp. novicida U112 metabolite:H+ symporter (MHS) family protein YP_897793.1 139163 D 401614 CDS YP_897794.1 118496744 4548485 140546..142324 1 NC_008601.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 142324 aspS 4548485 aspS Francisella tularensis subsp. novicida U112 aspartyl-tRNA synthetase YP_897794.1 140546 D 401614 CDS YP_897795.1 118496745 4548486 142461..143405 1 NC_008601.1 group 1 glycosyl transferase 143405 4548486 FTN_0130 Francisella tularensis subsp. novicida U112 group 1 glycosyl transferase YP_897795.1 142461 D 401614 CDS YP_897796.1 118496746 4548487 complement(143587..144894) 1 NC_008601.1 hypothetical protein 144894 4548487 FTN_0131 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897796.1 143587 R 401614 CDS YP_897797.1 118496747 4548488 complement(145232..146200) 1 NC_008601.1 hypothetical protein 146200 4548488 FTN_0132 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897797.1 145232 R 401614 CDS YP_897798.1 118496748 4548489 146389..148245 1 NC_008601.1 ribonuclease II family protein 148245 4548489 FTN_0133 Francisella tularensis subsp. novicida U112 ribonuclease II family protein YP_897798.1 146389 D 401614 CDS YP_897799.1 118496749 4548490 148576..149244 1 NC_008601.1 carboxylesterase/phospholipase family protein 149244 4548490 FTN_0134 Francisella tularensis subsp. novicida U112 carboxylesterase/phospholipase family protein YP_897799.1 148576 D 401614 CDS YP_897800.1 118496750 4548491 149241..150143 1 NC_008601.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 150143 hemC 4548491 hemC Francisella tularensis subsp. novicida U112 porphobilinogen deaminase YP_897800.1 149241 D 401614 CDS YP_897801.1 118496751 4548492 150192..150536 1 NC_008601.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 150536 crcB 4548492 crcB Francisella tularensis subsp. novicida U112 camphor resistance protein CrcB YP_897801.1 150192 D 401614 CDS YP_897802.1 118496752 4548493 150533..150940 1 NC_008601.1 hypothetical protein 150940 4548493 FTN_0137 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897802.1 150533 D 401614 CDS YP_897803.1 118496753 4548494 151080..151697 1 NC_008601.1 hypothetical protein 151697 4548494 FTN_0138 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897803.1 151080 D 401614 CDS YP_897804.1 118496754 4548495 complement(151694..151867) 1 NC_008601.1 hypothetical protein 151867 4548495 FTN_0139 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897804.1 151694 R 401614 CDS YP_897805.1 118496755 4548496 151997..153796 1 NC_008601.1 anion ABC transporter permease 153796 4548496 FTN_0140 Francisella tularensis subsp. novicida U112 anion ABC transporter permease YP_897805.1 151997 D 401614 CDS YP_897806.1 118496756 4548497 153815..155131 1 NC_008601.1 ABC transporter ATP-binding protein 155131 4548497 FTN_0141 Francisella tularensis subsp. novicida U112 ABC transporter ATP-binding protein YP_897806.1 153815 D 401614 CDS YP_897807.1 118496757 4548152 155218..156759 1 NC_008601.1 hypothetical protein 156759 4548152 FTN_0142 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897807.1 155218 D 401614 CDS YP_897808.1 118496758 4548153 156853..158739 1 NC_008601.1 monovalent cation:proton antiporter 158739 4548153 FTN_0143 Francisella tularensis subsp. novicida U112 monovalent cation:proton antiporter YP_897808.1 156853 D 401614 CDS YP_897809.1 118496759 4548154 158724..159263 1 NC_008601.1 carbonic anhydrase 159263 paaY 4548154 paaY Francisella tularensis subsp. novicida U112 carbonic anhydrase YP_897809.1 158724 D 401614 CDS YP_897810.1 118496760 4548155 159214..159858 1 NC_008601.1 outer membrane lipoprotein LolB 159858 lolB 4548155 lolB Francisella tularensis subsp. novicida U112 outer membrane lipoprotein LolB YP_897810.1 159214 D 401614 CDS YP_897811.1 118496761 4548156 159846..160673 1 NC_008601.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 160673 ipk 4548156 ipk Francisella tularensis subsp. novicida U112 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_897811.1 159846 D 401614 CDS YP_897812.1 118496762 4548158 160862..161491 1 NC_008601.1 hypothetical protein 161491 4548158 FTN_0148 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897812.1 160862 D 401614 CDS YP_897813.1 118496763 4548159 161561..162475 1 NC_008601.1 hypothetical protein 162475 4548159 FTN_0149 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897813.1 161561 D 401614 CDS YP_897814.1 118496764 4548160 162491..163060 1 NC_008601.1 YggT family protein 163060 4548160 FTN_0150 Francisella tularensis subsp. novicida U112 YggT family protein YP_897814.1 162491 D 401614 CDS YP_897815.1 118496765 4548161 complement(163054..163836) 1 NC_008601.1 ABC transporter ATP-binding protein 163836 4548161 FTN_0151 Francisella tularensis subsp. novicida U112 ABC transporter ATP-binding protein YP_897815.1 163054 R 401614 CDS YP_897816.1 118496766 4548162 complement(163865..165589) 1 NC_008601.1 anion ABC transporter permease 165589 4548162 FTN_0152 Francisella tularensis subsp. novicida U112 anion ABC transporter permease YP_897816.1 163865 R 401614 CDS YP_897817.1 118496767 4548163 complement(166018..166443) 1 NC_008601.1 RimI-like acetyltransferase 166443 4548163 FTN_0153 Francisella tularensis subsp. novicida U112 RimI-like acetyltransferase YP_897817.1 166018 R 401614 CDS YP_897818.1 118496768 4548164 complement(166430..167899) 1 NC_008601.1 glutathione synthase/ribosomal protein S6 modification protein 167899 rimK 4548164 rimK Francisella tularensis subsp. novicida U112 glutathione synthase/ribosomal protein S6 modification protein YP_897818.1 166430 R 401614 CDS YP_897819.1 118496769 4548165 168063..170078 1 NC_008601.1 competence protein 170078 4548165 FTN_0155 Francisella tularensis subsp. novicida U112 competence protein YP_897819.1 168063 D 401614 CDS YP_897820.1 118496770 4548166 170179..171066 1 NC_008601.1 putative acyltransferase 171066 plsC 4548166 plsC Francisella tularensis subsp. novicida U112 putative acyltransferase YP_897820.1 170179 D 401614 CDS YP_897821.1 118496771 4548167 complement(171468..172004) 1 NC_008601.1 hypothetical protein 172004 4548167 FTN_0157 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897821.1 171468 R 401614 CDS YP_897822.1 118496772 4548168 complement(172102..172644) 1 NC_008601.1 Sua5/YciO/YrdC family protein 172644 4548168 FTN_0158 Francisella tularensis subsp. novicida U112 Sua5/YciO/YrdC family protein YP_897822.1 172102 R 401614 CDS YP_897823.1 118496773 4548169 complement(172767..174437) 1 NC_008601.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 174437 rpsA 4548169 rpsA Francisella tularensis subsp. novicida U112 30S ribosomal protein S1 YP_897823.1 172767 R 401614 CDS YP_897824.1 118496774 4548760 174585..175046 1 NC_008601.1 zinc-binding protein 175046 4548760 FTN_0160 Francisella tularensis subsp. novicida U112 zinc-binding protein YP_897824.1 174585 D 401614 CDS YP_897825.1 118496775 4548761 175050..175940 1 NC_008601.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 175940 ddlB 4548761 ddlB Francisella tularensis subsp. novicida U112 D-alanyl-alanine synthetase A YP_897825.1 175050 D 401614 CDS YP_897826.1 118496776 4548762 175937..176620 1 NC_008601.1 cell division protein FtsQ 176620 ftsQ 4548762 ftsQ Francisella tularensis subsp. novicida U112 cell division protein FtsQ YP_897826.1 175937 D 401614 CDS YP_897827.1 118496777 4548763 176722..177984 1 NC_008601.1 cell division protein FtsA 177984 ftsA 4548763 ftsA Francisella tularensis subsp. novicida U112 cell division protein FtsA YP_897827.1 176722 D 401614 CDS YP_897828.1 118496778 4548764 178028..179173 1 NC_008601.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 179173 ftsZ 4548764 ftsZ Francisella tularensis subsp. novicida U112 cell division protein FtsZ YP_897828.1 178028 D 401614 CDS YP_897829.1 118496779 4548765 179199..180056 1 NC_008601.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 180056 lpxC 4548765 lpxC Francisella tularensis subsp. novicida U112 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase YP_897829.1 179199 D 401614 CDS YP_897830.1 118496780 4548766 complement(180070..181710) 1 NC_008601.1 DNA polymerase III subunit gamma and tau 181710 dnaX 4548766 dnaX Francisella tularensis subsp. novicida U112 DNA polymerase III subunit gamma and tau YP_897830.1 180070 R 401614 CDS YP_897831.1 118496781 4548767 181982..182959 1 NC_008601.1 peptide chain release factor 2 182959 prfB 4548767 prfB Francisella tularensis subsp. novicida U112 peptide chain release factor 2 YP_897831.1 181982 D 401614 CDS YP_897832.1 118496782 4548768 183091..184821 1 NC_008601.1 lysyl-tRNA synthetase 184821 lysU 4548768 lysU Francisella tularensis subsp. novicida U112 lysyl-tRNA synthetase YP_897832.1 183091 D 401614 CDS YP_897833.1 118496783 4548769 complement(185205..185747) 1 NC_008601.1 hypothetical protein 185747 4548769 FTN_0169 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897833.1 185205 R 401614 CDS YP_897834.1 118496784 4548770 complement(185846..186718) 1 NC_008601.1 hypothetical protein 186718 4548770 FTN_0170 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897834.1 185846 R 401614 CDS YP_897835.1 118496785 4548771 complement(186727..188268) 1 NC_008601.1 glutaminase 188268 glsA 4548771 glsA Francisella tularensis subsp. novicida U112 glutaminase YP_897835.1 186727 R 401614 CDS YP_897836.1 118496786 4548772 complement(188350..189387) 1 NC_008601.1 glutamine synthetase 189387 glnA 4548772 glnA Francisella tularensis subsp. novicida U112 glutamine synthetase YP_897836.1 188350 R 401614 CDS YP_897837.1 118496787 4548773 complement(189507..190484) 1 NC_008601.1 DNA polymerase III subunit delta 190484 holA 4548773 holA Francisella tularensis subsp. novicida U112 DNA polymerase III subunit delta YP_897837.1 189507 R 401614 CDS YP_897838.1 118496788 4548774 190570..191088 1 NC_008601.1 outer membrane lipoprotein 191088 blc 4548774 blc Francisella tularensis subsp. novicida U112 outer membrane lipoprotein YP_897838.1 190570 D 401614 CDS YP_897839.1 118496789 4548775 191251..192876 1 NC_008601.1 hypothetical protein 192876 4548775 FTN_0175 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897839.1 191251 D 401614 CDS YP_897840.1 118496790 4548776 193022..194290 1 NC_008601.1 serine permease 194290 4548776 FTN_0176 Francisella tularensis subsp. novicida U112 serine permease YP_897840.1 193022 D 401614 CDS YP_897841.1 118496791 4548777 complement(194356..195903) 1 NC_008601.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 195903 purH 4548777 purH Francisella tularensis subsp. novicida U112 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_897841.1 194356 R 401614 CDS YP_897842.1 118496792 4548778 196080..197366 1 NC_008601.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 197366 purA 4548778 purA Francisella tularensis subsp. novicida U112 adenylosuccinate synthetase YP_897842.1 196080 D 401614 CDS YP_897843.1 118496793 4548779 197370..197903 1 NC_008601.1 hypoxanthine-guanine phosphoribosyltransferase 197903 hpt 4548779 hpt Francisella tularensis subsp. novicida U112 hypoxanthine-guanine phosphoribosyltransferase YP_897843.1 197370 D 401614 CDS YP_897844.1 118496794 4547417 complement(197922..198641) 1 NC_008601.1 dienelactone hydrolase family protein 198641 4547417 FTN_0180 Francisella tularensis subsp. novicida U112 dienelactone hydrolase family protein YP_897844.1 197922 R 401614 CDS YP_897845.1 118496795 4547418 complement(198739..199581) 1 NC_008601.1 manganese/zinc/iron chelate uptake transporter (MZT) family protein 199581 4547418 FTN_0181 Francisella tularensis subsp. novicida U112 manganese/zinc/iron chelate uptake transporter (MZT) family protein YP_897845.1 198739 R 401614 CDS YP_897846.1 118496796 4547419 complement(199523..200200) 1 NC_008601.1 ATP-binding cassette (ABC) superfamily protein 200200 4547419 FTN_0182 Francisella tularensis subsp. novicida U112 ATP-binding cassette (ABC) superfamily protein YP_897846.1 199523 R 401614 CDS YP_897847.1 118496797 4547420 complement(200202..201119) 1 NC_008601.1 periplasmic solute binding family protein 201119 4547420 FTN_0183 Francisella tularensis subsp. novicida U112 periplasmic solute binding family protein YP_897847.1 200202 R 401614 CDS YP_897848.1 118496798 4547421 complement(201194..202417) 1 NC_008601.1 major facilitator transporter 202417 4547421 FTN_0184 Francisella tularensis subsp. novicida U112 major facilitator transporter YP_897848.1 201194 R 401614 CDS YP_897849.1 118496799 4547422 complement(202538..203002) 1 NC_008601.1 outer membrane lipoprotein 203002 4547422 FTN_0185 Francisella tularensis subsp. novicida U112 outer membrane lipoprotein YP_897849.1 202538 R 401614 CDS YP_897850.1 118496800 4547423 complement(203013..203609) 1 NC_008601.1 trp repressor binding protein 203609 wrbA 4547423 wrbA Francisella tularensis subsp. novicida U112 trp repressor binding protein YP_897850.1 203013 R 401614 CDS YP_897851.1 118496801 4547424 203616..204812 1 NC_008601.1 tRNA processing ribonuclease BN 204812 rbn 4547424 rbn Francisella tularensis subsp. novicida U112 tRNA processing ribonuclease BN YP_897851.1 203616 D 401614 CDS YP_897852.1 118496802 4547425 204831..205406 1 NC_008601.1 nicotinamide ribonucleoside (NR) uptake permease (PnuC) family protein 205406 4547425 FTN_0188 Francisella tularensis subsp. novicida U112 nicotinamide ribonucleoside (NR) uptake permease (PnuC) family protein YP_897852.1 204831 D 401614 CDS YP_897853.1 118496803 4547426 205403..207556 1 NC_008601.1 primosomal protein N 207556 priA 4547426 priA Francisella tularensis subsp. novicida U112 primosomal protein N YP_897853.1 205403 D 401614 CDS YP_897854.1 118496804 4547427 complement(207623..208801) 1 NC_008601.1 drug:H+ antiporter-1 (DHA1) family protein 208801 4547427 FTN_0190 Francisella tularensis subsp. novicida U112 drug:H+ antiporter-1 (DHA1) family protein YP_897854.1 207623 R 401614 CDS YP_897855.1 118496805 4547428 complement(208869..209609) 1 NC_008601.1 polar amino acid uptake transporter 209609 4547428 FTN_0191 Francisella tularensis subsp. novicida U112 polar amino acid uptake transporter YP_897855.1 208869 R 401614 CDS YP_897856.1 118496806 4547429 complement(209802..210995) 1 NC_008601.1 cytochrome bd-I terminal oxidase subunit II 210995 cydB 4547429 cydB Francisella tularensis subsp. novicida U112 cytochrome bd-I terminal oxidase subunit II YP_897856.1 209802 R 401614 CDS YP_897857.1 118496807 4547430 complement(211006..212760) 1 NC_008601.1 cytochrome bd-I terminal oxidase subunit I 212760 cydA 4547430 cydA Francisella tularensis subsp. novicida U112 cytochrome bd-I terminal oxidase subunit I YP_897857.1 211006 R 401614 CDS YP_897858.1 118496808 4547431 complement(213217..214584) 1 NC_008601.1 major facilitator transporter 214584 4547431 FTN_0194 Francisella tularensis subsp. novicida U112 major facilitator transporter YP_897858.1 213217 R 401614 CDS YP_897859.1 118496809 4547432 216593..217495 1 NC_008601.1 cytochrome bo terminal oxidase subunit II 217495 cyoA 4547432 cyoA Francisella tularensis subsp. novicida U112 cytochrome bo terminal oxidase subunit II YP_897859.1 216593 D 401614 CDS YP_897860.1 118496810 4547433 217534..219564 1 NC_008601.1 cytochrome bo terminal oxidase subunit I 219564 cyoB 4547433 cyoB Francisella tularensis subsp. novicida U112 cytochrome bo terminal oxidase subunit I YP_897860.1 217534 D 401614 CDS YP_897861.1 118496811 4547434 219561..220163 1 NC_008601.1 cytochrome bo terminal oxidase subunit III 220163 cyoC 4547434 cyoC Francisella tularensis subsp. novicida U112 cytochrome bo terminal oxidase subunit III YP_897861.1 219561 D 401614 CDS YP_897862.1 118496812 4547550 220165..220497 1 NC_008601.1 cytochrome bo terminal oxidase subunit IV 220497 cyoD 4547550 cyoD Francisella tularensis subsp. novicida U112 cytochrome bo terminal oxidase subunit IV YP_897862.1 220165 D 401614 CDS YP_897863.1 118496813 4547551 220528..221376 1 NC_008601.1 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 221376 cyoE 4547551 cyoE Francisella tularensis subsp. novicida U112 protoheme IX farnesyltransferase YP_897863.1 220528 D 401614 CDS YP_897864.1 118496814 4547552 complement(221521..222564) 1 NC_008601.1 UDP-3-O-[3-fatty acid] glucosamine N-acyltransferase 222564 4547552 FTN_0200 Francisella tularensis subsp. novicida U112 UDP-3-O-[3-fatty acid] glucosamine N-acyltransferase YP_897864.1 221521 R 401614 CDS YP_897865.1 118496815 4547553 complement(222639..223334) 1 NC_008601.1 hypothetical protein 223334 4547553 FTN_0201 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897865.1 222639 R 401614 CDS YP_897866.1 118496816 4547554 complement(223334..224185) 1 NC_008601.1 pyridoxal kinase 224185 pdxY 4547554 pdxY Francisella tularensis subsp. novicida U112 pyridoxal kinase YP_897866.1 223334 R 401614 CDS YP_897867.1 118496817 4547555 complement(224192..224626) 1 NC_008601.1 hypothetical protein 224626 4547555 FTN_0203 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897867.1 224192 R 401614 CDS YP_897868.1 118496818 4547556 224772..225728 1 NC_008601.1 methanol dehydrogenase regulatory protein 225728 4547556 FTN_0204 Francisella tularensis subsp. novicida U112 methanol dehydrogenase regulatory protein YP_897868.1 224772 D 401614 CDS YP_897869.1 118496819 4547557 225741..226652 1 NC_008601.1 hypothetical protein 226652 4547557 FTN_0205 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897869.1 225741 D 401614 CDS YP_897870.1 118496820 4547558 226642..227118 1 NC_008601.1 hypothetical protein 227118 4547558 FTN_0206 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897870.1 226642 D 401614 CDS YP_897871.1 118496821 4547559 227115..228116 1 NC_008601.1 von Willebrand factor type A domain-containing protein 228116 4547559 FTN_0207 Francisella tularensis subsp. novicida U112 von Willebrand factor type A domain-containing protein YP_897871.1 227115 D 401614 CDS YP_897872.1 118496822 4547560 228118..229116 1 NC_008601.1 hypothetical protein 229116 4547560 FTN_0208 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897872.1 228118 D 401614 CDS YP_897873.1 118496823 4547561 229107..229976 1 NC_008601.1 hypothetical protein 229976 4547561 FTN_0209 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897873.1 229107 D 401614 CDS YP_897874.1 118496824 4547562 229966..231591 1 NC_008601.1 hypothetical protein 231591 4547562 FTN_0210 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897874.1 229966 D 401614 CDS YP_897875.1 118496825 4547563 231598..232266 1 NC_008601.1 pyrrolidone carboxylylate peptidase 232266 pcp 4547563 pcp Francisella tularensis subsp. novicida U112 pyrrolidone carboxylylate peptidase YP_897875.1 231598 D 401614 CDS YP_897876.1 118496826 4547564 232274..232756 1 NC_008601.1 putative cytochrome c-type biogenesis protein 232756 4547564 FTN_0212 Francisella tularensis subsp. novicida U112 putative cytochrome c-type biogenesis protein YP_897876.1 232274 D 401614 CDS YP_897877.1 118496827 4547565 232787..233227 1 NC_008601.1 DNA polymerase III subunit chi 233227 holC 4547565 holC Francisella tularensis subsp. novicida U112 DNA polymerase III subunit chi YP_897877.1 232787 D 401614 CDS YP_897878.1 118496828 4547566 234222..236981 1 NC_008601.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 236981 valS 4547566 valS Francisella tularensis subsp. novicida U112 valyl-tRNA synthetase YP_897878.1 234222 D 401614 CDS YP_897879.1 118496829 4547567 237281..237946 1 NC_008601.1 hypothetical protein 237946 4547567 FTN_0215 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897879.1 237281 D 401614 CDS YP_897880.1 118496830 4547568 238094..238429 1 NC_008601.1 hypothetical protein 238429 4547568 FTN_0216 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897880.1 238094 D 401614 CDS YP_897881.1 118496831 4547817 complement(238426..239583) 1 NC_008601.1 L-lactate dehydrogenase 239583 4547817 FTN_0217 Francisella tularensis subsp. novicida U112 L-lactate dehydrogenase YP_897881.1 238426 R 401614 CDS YP_897882.1 118496832 4547818 complement(240473..241126) 1 NC_008601.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase 241126 nfnB 4547818 nfnB Francisella tularensis subsp. novicida U112 dihydropteridine reductase YP_897882.1 240473 R 401614 CDS YP_897883.1 118496833 4547819 241266..241643 1 NC_008601.1 MutT/nudix family protein 241643 4547819 FTN_0219 Francisella tularensis subsp. novicida U112 MutT/nudix family protein YP_897883.1 241266 D 401614 CDS YP_897884.1 118496834 4547820 241817..243208 1 NC_008601.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 243208 fumC 4547820 fumC Francisella tularensis subsp. novicida U112 fumarate hydratase YP_897884.1 241817 D 401614 CDS YP_897885.1 118496835 4547821 243339..244745 1 NC_008601.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 244745 gltX 4547821 gltX Francisella tularensis subsp. novicida U112 glutamyl-tRNA synthetase YP_897885.1 243339 D 401614 CDS YP_897886.1 118496836 4547822 244745..245713 1 NC_008601.1 hypothetical protein 245713 4547822 FTN_0222 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897886.1 244745 D 401614 CDS YP_897887.1 118496837 4547823 246583..248121 1 NC_008601.1 amino acid-polyamine-organocation (APC) superfamily protein 248121 4547823 FTN_0223 Francisella tularensis subsp. novicida U112 amino acid-polyamine-organocation (APC) superfamily protein YP_897887.1 246583 D 401614 CDS YP_897888.1 118496838 4547825 complement(248452..249375) 1 NC_008601.1 hypothetical protein 249375 4547825 FTN_0225 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897888.1 248452 R 401614 CDS YP_897889.1 118496839 4547826 complement(249457..249999) 1 NC_008601.1 dihydrofolate reductase type I 249999 folA 4547826 folA Francisella tularensis subsp. novicida U112 dihydrofolate reductase type I YP_897889.1 249457 R 401614 CDS YP_897890.1 118496840 4547827 250191..250910 1 NC_008601.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 250910 rpsB 4547827 rpsB Francisella tularensis subsp. novicida U112 30S ribosomal protein S2 YP_897890.1 250191 D 401614 CDS YP_897891.1 118496841 4547828 250932..251801 1 NC_008601.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 251801 tsf 4547828 tsf Francisella tularensis subsp. novicida U112 elongation factor Ts YP_897891.1 250932 D 401614 CDS YP_897892.1 118496842 4547829 251805..252554 1 NC_008601.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 252554 pyrH 4547829 pyrH Francisella tularensis subsp. novicida U112 uridylate kinase YP_897892.1 251805 D 401614 CDS YP_897893.1 118496843 4547830 252583..253140 1 NC_008601.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 253140 frr 4547830 frr Francisella tularensis subsp. novicida U112 ribosome recycling factor YP_897893.1 252583 D 401614 CDS YP_897894.1 118496844 4547831 253173..253946 1 NC_008601.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 253946 uppS 4547831 uppS Francisella tularensis subsp. novicida U112 undecaprenyl pyrophosphate synthase YP_897894.1 253173 D 401614 CDS YP_897895.1 118496845 4547832 253960..254754 1 NC_008601.1 phosphatidate cytidylyltransferase 254754 cdsA 4547832 cdsA Francisella tularensis subsp. novicida U112 phosphatidate cytidylyltransferase YP_897895.1 253960 D 401614 CDS YP_897896.1 118496846 4548386 254764..255210 1 NC_008601.1 deoxyuridine 5'- triphosphate nucleotidohydrolase; catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 255210 dut 4548386 dut Francisella tularensis subsp. novicida U112 deoxyuridine 5'-triphosphate nucleotidohydrolase YP_897896.1 254764 D 401614 CDS YP_897897.1 118496847 4548387 255214..255810 1 NC_008601.1 phosphatidylglycerophosphate synthetase 255810 pgsA 4548387 pgsA Francisella tularensis subsp. novicida U112 phosphatidylglycerophosphate synthetase YP_897897.1 255214 D 401614 CDS YP_897898.1 118496848 4548388 255945..256319 1 NC_008601.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 256319 rpsL 4548388 rpsL Francisella tularensis subsp. novicida U112 30S ribosomal protein S12 YP_897898.1 255945 D 401614 CDS YP_897899.1 118496849 4548389 256358..256831 1 NC_008601.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 256831 rpsG 4548389 rpsG Francisella tularensis subsp. novicida U112 30S ribosomal protein S7 YP_897899.1 256358 D 401614 CDS YP_897900.1 118496850 4548390 256846..258960 1 NC_008601.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 258960 fusA 4548390 fusA Francisella tularensis subsp. novicida U112 elongation factor G YP_897900.1 256846 D 401614 CDS YP_897901.1 118496851 4548391 258981..259298 1 NC_008601.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 259298 rpsJ 4548391 rpsJ Francisella tularensis subsp. novicida U112 30S ribosomal protein S10 YP_897901.1 258981 D 401614 CDS YP_897902.1 118496852 4548392 259402..260034 1 NC_008601.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 260034 rplC 4548392 rplC Francisella tularensis subsp. novicida U112 50S ribosomal protein L3 YP_897902.1 259402 D 401614 CDS YP_897903.1 118496853 4548393 260067..260690 1 NC_008601.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 260690 rplD 4548393 rplD Francisella tularensis subsp. novicida U112 50S ribosomal protein L4 YP_897903.1 260067 D 401614 CDS YP_897904.1 118496854 4548394 260687..260986 1 NC_008601.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 260986 rplW 4548394 rplW Francisella tularensis subsp. novicida U112 50S ribosomal protein L23 YP_897904.1 260687 D 401614 CDS YP_897905.1 118496855 4548395 261008..261832 1 NC_008601.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 261832 rplB 4548395 rplB Francisella tularensis subsp. novicida U112 50S ribosomal protein L2 YP_897905.1 261008 D 401614 CDS YP_897906.1 118496856 4548396 261847..262125 1 NC_008601.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 262125 rpsS 4548396 rpsS Francisella tularensis subsp. novicida U112 30S ribosomal protein S19 YP_897906.1 261847 D 401614 CDS YP_897907.1 118496857 4548397 262141..262476 1 NC_008601.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 262476 rplV 4548397 rplV Francisella tularensis subsp. novicida U112 50S ribosomal protein L22 YP_897907.1 262141 D 401614 CDS YP_897908.1 118496858 4548398 262491..263162 1 NC_008601.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 263162 rpsC 4548398 rpsC Francisella tularensis subsp. novicida U112 30S ribosomal protein S3 YP_897908.1 262491 D 401614 CDS YP_897909.1 118496859 4548399 263162..263575 1 NC_008601.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 263575 rplP 4548399 rplP Francisella tularensis subsp. novicida U112 50S ribosomal protein L16 YP_897909.1 263162 D 401614 CDS YP_897910.1 118496860 4548400 263575..263775 1 NC_008601.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 263775 rpmC 4548400 rpmC Francisella tularensis subsp. novicida U112 50S ribosomal protein L29 YP_897910.1 263575 D 401614 CDS YP_897911.1 118496861 4548401 263788..264039 1 NC_008601.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 264039 rpsQ 4548401 rpsQ Francisella tularensis subsp. novicida U112 30S ribosomal protein S17 YP_897911.1 263788 D 401614 CDS YP_897912.1 118496862 4548402 264131..264499 1 NC_008601.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 264499 rplN 4548402 rplN Francisella tularensis subsp. novicida U112 50S ribosomal protein L14 YP_897912.1 264131 D 401614 CDS YP_897913.1 118496863 4548403 264521..264838 1 NC_008601.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 264838 rplX 4548403 rplX Francisella tularensis subsp. novicida U112 50S ribosomal protein L24 YP_897913.1 264521 D 401614 CDS YP_897914.1 118496864 4548404 264850..265389 1 NC_008601.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 265389 rplE 4548404 rplE Francisella tularensis subsp. novicida U112 50S ribosomal protein L5 YP_897914.1 264850 D 401614 CDS YP_897915.1 118496865 4547435 265408..265713 1 NC_008601.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 265713 rpsN 4547435 rpsN Francisella tularensis subsp. novicida U112 30S ribosomal protein S14 YP_897915.1 265408 D 401614 CDS YP_897916.1 118496866 4547436 265730..266128 1 NC_008601.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 266128 rpsH 4547436 rpsH Francisella tularensis subsp. novicida U112 30S ribosomal protein S8 YP_897916.1 265730 D 401614 CDS YP_897917.1 118496867 4547437 266147..266683 1 NC_008601.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 266683 rplF 4547437 rplF Francisella tularensis subsp. novicida U112 50S ribosomal protein L6 YP_897917.1 266147 D 401614 CDS YP_897918.1 118496868 4547438 266706..267059 1 NC_008601.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 267059 rplR 4547438 rplR Francisella tularensis subsp. novicida U112 50S ribosomal protein L18 YP_897918.1 266706 D 401614 CDS YP_897919.1 118496869 4547439 267087..267587 1 NC_008601.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 267587 rpsE 4547439 rpsE Francisella tularensis subsp. novicida U112 30S ribosomal protein S5 YP_897919.1 267087 D 401614 CDS YP_897920.1 118496870 4547440 267594..267779 1 NC_008601.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 267779 rpmD 4547440 rpmD Francisella tularensis subsp. novicida U112 50S ribosomal protein L30 YP_897920.1 267594 D 401614 CDS YP_897921.1 118496871 4547441 267786..268217 1 NC_008601.1 late assembly protein; 50S ribosomal protein L15 268217 rplO 4547441 rplO Francisella tularensis subsp. novicida U112 50S ribosomal protein L15 YP_897921.1 267786 D 401614 CDS YP_897922.1 118496872 4547442 268228..269553 1 NC_008601.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 269553 secY 4547442 secY Francisella tularensis subsp. novicida U112 preprotein translocase subunit SecY YP_897922.1 268228 D 401614 CDS YP_897923.1 118496873 4547443 269577..269690 1 NC_008601.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 269690 rpmJ 4547443 rpmJ Francisella tularensis subsp. novicida U112 50S ribosomal protein L36 YP_897923.1 269577 D 401614 CDS YP_897924.1 118496874 4547444 269807..270163 1 NC_008601.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 270163 rpsM 4547444 rpsM Francisella tularensis subsp. novicida U112 30S ribosomal protein S13 YP_897924.1 269807 D 401614 CDS YP_897925.1 118496875 4547445 270202..270591 1 NC_008601.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 270591 rpsK 4547445 rpsK Francisella tularensis subsp. novicida U112 30S ribosomal protein S11 YP_897925.1 270202 D 401614 CDS YP_897926.1 118496876 4547446 270613..271233 1 NC_008601.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 271233 rpsD 4547446 rpsD Francisella tularensis subsp. novicida U112 30S ribosomal protein S4 YP_897926.1 270613 D 401614 CDS YP_897927.1 118496877 4547447 271291..272262 1 NC_008601.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 272262 rpoA 4547447 rpoA Francisella tularensis subsp. novicida U112 DNA-directed RNA polymerase subunit alpha YP_897927.1 271291 D 401614 CDS YP_897928.1 118496878 4547448 272307..272744 1 NC_008601.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 272744 rplQ 4547448 rplQ Francisella tularensis subsp. novicida U112 50S ribosomal protein L17 YP_897928.1 272307 D 401614 CDS YP_897929.1 118496879 4547449 272930..274816 1 NC_008601.1 molecular chaperone; heat shock protein 90 274816 htpG 4547449 htpG Francisella tularensis subsp. novicida U112 heat shock protein 90 YP_897929.1 272930 D 401614 CDS YP_897930.1 118496880 4547450 274900..275403 1 NC_008601.1 hypothetical protein 275403 4547450 FTN_0267 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897930.1 274900 D 401614 CDS YP_897931.1 118496881 4547452 complement(275911..277422) 1 NC_008601.1 hypothetical protein 277422 4547452 FTN_0269 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897931.1 275911 R 401614 CDS YP_897932.1 118496882 4547453 277740..279380 1 NC_008601.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 279380 pyrG 4547453 pyrG Francisella tularensis subsp. novicida U112 CTP synthetase YP_897932.1 277740 D 401614 CDS YP_897933.1 118496883 4547454 279453..279875 1 NC_008601.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 279875 ndk 4547454 ndk Francisella tularensis subsp. novicida U112 nucleoside diphosphate kinase YP_897933.1 279453 D 401614 CDS YP_897934.1 118496884 4548368 279916..280818 1 NC_008601.1 acetyl-CoA carboxylase, carboxytransferase subunit beta 280818 accD 4548368 accD Francisella tularensis subsp. novicida U112 acetyl-CoA carboxylase, carboxytransferase subunit beta YP_897934.1 279916 D 401614 CDS YP_897935.1 118496885 4548369 280833..282014 1 NC_008601.1 folylpoly-gamma-glutamate synthetase/ dihydrofolate synthetase 282014 folC 4548369 folC Francisella tularensis subsp. novicida U112 folylpoly-gamma-glutamate synthetase/ dihydrofolate synthetase YP_897935.1 280833 D 401614 CDS YP_897936.1 118496886 4548370 281992..282402 1 NC_008601.1 hypothetical protein 282402 4548370 FTN_0274 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897936.1 281992 D 401614 CDS YP_897937.1 118496887 4548371 282485..283543 1 NC_008601.1 hypothetical protein 283543 4548371 FTN_0275 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897937.1 282485 D 401614 CDS YP_897938.1 118496888 4548372 283566..285107 1 NC_008601.1 multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) transporter 285107 mviN 4548372 mviN Francisella tularensis subsp. novicida U112 multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) transporter YP_897938.1 283566 D 401614 CDS YP_897939.1 118496889 4548373 285160..286665 1 NC_008601.1 glutamate-cysteine ligase 286665 gshA 4548373 gshA Francisella tularensis subsp. novicida U112 glutamate-cysteine ligase YP_897939.1 285160 D 401614 CDS YP_897940.1 118496890 4548374 complement(286878..287093) 1 NC_008601.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 287093 rpmE 4548374 rpmE Francisella tularensis subsp. novicida U112 50S ribosomal protein L31 YP_897940.1 286878 R 401614 CDS YP_897941.1 118496891 4548375 complement(287215..287946) 1 NC_008601.1 oxidoreductase 287946 4548375 FTN_0279 Francisella tularensis subsp. novicida U112 oxidoreductase YP_897941.1 287215 R 401614 CDS YP_897942.1 118496892 4548376 288029..288424 1 NC_008601.1 hypothetical protein 288424 4548376 FTN_0280 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897942.1 288029 D 401614 CDS YP_897943.1 118496893 4548377 288433..288882 1 NC_008601.1 hypothetical protein 288882 4548377 FTN_0281 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897943.1 288433 D 401614 CDS YP_897944.1 118496894 4548378 288913..289809 1 NC_008601.1 hypothetical protein 289809 4548378 FTN_0282 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897944.1 288913 D 401614 CDS YP_897945.1 118496895 4548380 291793..292797 1 NC_008601.1 prophage maintenance system killer protein (DOC) 292797 4548380 FTN_0284 Francisella tularensis subsp. novicida U112 prophage maintenance system killer protein (DOC) YP_897945.1 291793 D 401614 CDS YP_897946.1 118496896 4548381 292790..294010 1 NC_008601.1 type I restriction-modification system subunit S 294010 4548381 FTN_0285 Francisella tularensis subsp. novicida U112 type I restriction-modification system subunit S YP_897946.1 292790 D 401614 CDS YP_897947.1 118496897 4548382 294223..294786 1 NC_008601.1 transposase 294786 4548382 FTN_0286 Francisella tularensis subsp. novicida U112 transposase YP_897947.1 294223 D 401614 CDS YP_897948.1 118496898 4548383 294845..295612 1 NC_008601.1 type I restriction-modification system subunit R (restriction) 295612 4548383 FTN_0287 Francisella tularensis subsp. novicida U112 type I restriction-modification system subunit R (restriction) YP_897948.1 294845 D 401614 CDS YP_897949.1 118496899 4548385 296016..296717 1 NC_008601.1 activator of osmoprotectant transporter ProP 296717 proQ 4548385 proQ Francisella tularensis subsp. novicida U112 activator of osmoprotectant transporter ProP YP_897949.1 296016 D 401614 CDS YP_897950.1 118496900 4547681 296739..297284 1 NC_008601.1 hypothetical protein 297284 4547681 FTN_0290 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897950.1 296739 D 401614 CDS YP_897951.1 118496901 4547682 complement(297299..298753) 1 NC_008601.1 K+ transporter (Trk) family protein 298753 trkH 4547682 trkH Francisella tularensis subsp. novicida U112 K+ transporter (Trk) family protein YP_897951.1 297299 R 401614 CDS YP_897952.1 118496902 4547683 298865..299068 1 NC_008601.1 hypothetical protein 299068 4547683 FTN_0292 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897952.1 298865 D 401614 CDS YP_897953.1 118496903 4547684 complement(299467..300084) 1 NC_008601.1 lipoprotein releasing system subunit A, outer membrane lipoproteins carrier 300084 lolA 4547684 lolA Francisella tularensis subsp. novicida U112 lipoprotein releasing system subunit A, outer membrane lipoproteins carrier YP_897953.1 299467 R 401614 CDS YP_897954.1 118496904 4547685 complement(300085..302586) 1 NC_008601.1 cell division protein 302586 ftsK 4547685 ftsK Francisella tularensis subsp. novicida U112 cell division protein YP_897954.1 300085 R 401614 CDS YP_897955.1 118496905 4547686 302708..303376 1 NC_008601.1 phosphatidic acid phosphatase PAP2 superfamily protein 303376 4547686 FTN_0295 Francisella tularensis subsp. novicida U112 phosphatidic acid phosphatase PAP2 superfamily protein YP_897955.1 302708 D 401614 CDS YP_897956.1 118496906 4547687 303623..305077 1 NC_008601.1 lysine:H+ symporter 305077 lysP 4547687 lysP Francisella tularensis subsp. novicida U112 lysine:H+ symporter YP_897956.1 303623 D 401614 CDS YP_897957.1 118496907 4547688 305086..305724 1 NC_008601.1 hypothetical protein 305724 4547688 FTN_0297 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897957.1 305086 D 401614 CDS YP_897958.1 118496908 4547689 305744..306730 1 NC_008601.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 306730 glpX 4547689 glpX Francisella tularensis subsp. novicida U112 fructose 1,6-bisphosphatase II YP_897958.1 305744 D 401614 CDS YP_897959.1 118496909 4547690 306996..308504 1 NC_008601.1 proline:Na+ symporter 308504 putP 4547690 putP Francisella tularensis subsp. novicida U112 proline:Na+ symporter YP_897959.1 306996 D 401614 CDS YP_897960.1 118496910 4547691 308570..310249 1 NC_008601.1 glycosyl transferase 310249 4547691 FTN_0300 Francisella tularensis subsp. novicida U112 glycosyl transferase YP_897960.1 308570 D 401614 CDS YP_897961.1 118496911 4547692 310260..311567 1 NC_008601.1 HlyC/CorC family transporter-associated protein 311567 4547692 FTN_0301 Francisella tularensis subsp. novicida U112 HlyC/CorC family transporter-associated protein YP_897961.1 310260 D 401614 CDS YP_897962.1 118496912 4547693 311638..311985 1 NC_008601.1 hypothetical protein 311985 4547693 FTN_0302 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897962.1 311638 D 401614 CDS YP_897963.1 118496913 4547694 311969..312895 1 NC_008601.1 hypothetical protein 312895 4547694 FTN_0303 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897963.1 311969 D 401614 CDS YP_897964.1 118496914 4547695 312892..314298 1 NC_008601.1 pilus assembly protein 314298 4547695 FTN_0304 Francisella tularensis subsp. novicida U112 pilus assembly protein YP_897964.1 312892 D 401614 CDS YP_897965.1 118496915 4547696 314309..314929 1 NC_008601.1 pilus assembly protein 314929 4547696 FTN_0305 Francisella tularensis subsp. novicida U112 pilus assembly protein YP_897965.1 314309 D 401614 CDS YP_897966.1 118496916 4547697 315040..315717 1 NC_008601.1 pilus assembly protein 315717 4547697 FTN_0306 Francisella tularensis subsp. novicida U112 pilus assembly protein YP_897966.1 315040 D 401614 CDS YP_897967.1 118496917 4547698 315736..316656 1 NC_008601.1 hypothetical protein 316656 4547698 FTN_0307 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897967.1 315736 D 401614 CDS YP_897968.1 118496918 4547699 316669..318477 1 NC_008601.1 membrane protein 318477 4547699 FTN_0308 Francisella tularensis subsp. novicida U112 membrane protein YP_897968.1 316669 D 401614 CDS YP_897969.1 118496919 4547700 318501..320306 1 NC_008601.1 hypothetical protein 320306 4547700 FTN_0309 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897969.1 318501 D 401614 CDS YP_897970.1 118496920 4548405 320389..321768 1 NC_008601.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 321768 cysS 4548405 cysS Francisella tularensis subsp. novicida U112 cysteinyl-tRNA synthetase YP_897970.1 320389 D 401614 CDS YP_897971.1 118496921 4548406 321772..322716 1 NC_008601.1 involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 322716 4548406 FTN_0311 Francisella tularensis subsp. novicida U112 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase YP_897971.1 321772 D 401614 CDS YP_897972.1 118496922 4548407 322772..323962 1 NC_008601.1 drug:H+ antiporter-1 (DHA1) family protein 323962 4548407 FTN_0312 Francisella tularensis subsp. novicida U112 drug:H+ antiporter-1 (DHA1) family protein YP_897972.1 322772 D 401614 CDS YP_897973.1 118496923 4548408 323976..324467 1 NC_008601.1 acetyltransferase 324467 4548408 FTN_0313 Francisella tularensis subsp. novicida U112 acetyltransferase YP_897973.1 323976 D 401614 CDS YP_897974.1 118496924 4548409 complement(324491..324814) 1 NC_008601.1 hypothetical protein 324814 4548409 FTN_0314 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897974.1 324491 R 401614 CDS YP_897975.1 118496925 4548410 complement(324845..325591) 1 NC_008601.1 traT-like protein 325591 4548410 FTN_0315 Francisella tularensis subsp. novicida U112 traT-like protein YP_897975.1 324845 R 401614 CDS YP_897976.1 118496926 4548411 complement(325736..326791) 1 NC_008601.1 alanine racemase 326791 4548411 FTN_0316 Francisella tularensis subsp. novicida U112 alanine racemase YP_897976.1 325736 R 401614 CDS YP_897977.1 118496927 4548412 326808..328172 1 NC_008601.1 amino acid transporter 328172 4548412 FTN_0317 Francisella tularensis subsp. novicida U112 amino acid transporter YP_897977.1 326808 D 401614 CDS YP_897978.1 118496928 4548413 complement(328174..328455) 1 NC_008601.1 hypothetical protein 328455 4548413 FTN_0318 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897978.1 328174 R 401614 CDS YP_897979.1 118496929 4548414 complement(328468..329970) 1 NC_008601.1 amino acid-polyamine-organocation family protein 329970 4548414 FTN_0319 Francisella tularensis subsp. novicida U112 amino acid-polyamine-organocation family protein YP_897979.1 328468 R 401614 CDS YP_897980.1 118496930 4548415 complement(330336..331079) 1 NC_008601.1 hypothetical protein 331079 4548415 FTN_0320 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897980.1 330336 R 401614 CDS YP_897981.1 118496931 4548416 complement(331082..331777) 1 NC_008601.1 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 331777 ubiG 4548416 ubiG Francisella tularensis subsp. novicida U112 3-demethylubiquinone-9 3-methyltransferase YP_897981.1 331082 R 401614 CDS YP_897982.1 118496932 4548417 331919..333019 1 NC_008601.1 VacJ like lipoprotein 333019 4548417 FTN_0322 Francisella tularensis subsp. novicida U112 VacJ like lipoprotein YP_897982.1 331919 D 401614 CDS YP_897983.1 118496933 4548418 complement(333238..333474) 1 NC_008601.1 BolA family protein 333474 4548418 FTN_0323 Francisella tularensis subsp. novicida U112 BolA family protein YP_897983.1 333238 R 401614 CDS YP_897984.1 118496934 4548419 complement(333491..333784) 1 NC_008601.1 hypothetical protein 333784 4548419 FTN_0324 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897984.1 333491 R 401614 CDS YP_897985.1 118496935 4548420 complement(333784..334446) 1 NC_008601.1 membrane protein 334446 4548420 FTN_0325 Francisella tularensis subsp. novicida U112 membrane protein YP_897985.1 333784 R 401614 CDS YP_897986.1 118496936 4548421 complement(334521..335054) 1 NC_008601.1 hypothetical protein 335054 4548421 FTN_0326 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897986.1 334521 R 401614 CDS YP_897987.1 118496937 4548422 complement(335054..335818) 1 NC_008601.1 ABC-type transport system permease 335818 4548422 FTN_0327 Francisella tularensis subsp. novicida U112 ABC-type transport system permease YP_897987.1 335054 R 401614 CDS YP_897988.1 118496938 4548423 complement(335822..336625) 1 NC_008601.1 ABC transporter ATP-binding protein 336625 4548423 FTN_0328 Francisella tularensis subsp. novicida U112 ABC transporter ATP-binding protein YP_897988.1 335822 R 401614 CDS YP_897989.1 118496939 4548800 complement(336639..336911) 1 NC_008601.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 336911 minE 4548800 minE Francisella tularensis subsp. novicida U112 cell division topological specificity factor MinE YP_897989.1 336639 R 401614 CDS YP_897990.1 118496940 4548801 complement(336914..337738) 1 NC_008601.1 septum site-determining protein MinD 337738 minD 4548801 minD Francisella tularensis subsp. novicida U112 septum site-determining protein MinD YP_897990.1 336914 R 401614 CDS YP_897991.1 118496941 4548802 complement(337778..338464) 1 NC_008601.1 septum site-determining protein MinC 338464 minC 4548802 minC Francisella tularensis subsp. novicida U112 septum site-determining protein MinC YP_897991.1 337778 R 401614 CDS YP_897992.1 118496942 4548803 complement(338499..338654) 1 NC_008601.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 338654 rpmG 4548803 rpmG Francisella tularensis subsp. novicida U112 50S ribosomal protein L33 YP_897992.1 338499 R 401614 CDS YP_897993.1 118496943 4548804 complement(338681..338917) 1 NC_008601.1 required for 70S ribosome assembly; 50S ribosomal protein L28 338917 rpmB 4548804 rpmB Francisella tularensis subsp. novicida U112 50S ribosomal protein L28 YP_897993.1 338681 R 401614 CDS YP_897994.1 118496944 4548805 complement(339051..339395) 1 NC_008601.1 hypothetical protein 339395 4548805 FTN_0334 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897994.1 339051 R 401614 CDS YP_897995.1 118496945 4548806 339525..341564 1 NC_008601.1 ATP-dependent DNA helicase RecG 341564 recG 4548806 recG Francisella tularensis subsp. novicida U112 ATP-dependent DNA helicase RecG YP_897995.1 339525 D 401614 CDS YP_897996.1 118496946 4548807 341568..341765 1 NC_008601.1 hypothetical protein 341765 4548807 FTN_0336 Francisella tularensis subsp. novicida U112 hypothetical protein YP_897996.1 341568 D 401614 CDS YP_897997.1 118496947 4548808 342333..343847 1 NC_008601.1 fumerate hydratase 343847 fumA 4548808 fumA Francisella tularensis subsp. novicida U112 fumerate hydratase YP_897997.1 342333 D 401614 CDS YP_897998.1 118496948 4548809 344391..345038 1 NC_008601.1 MutT/nudix family protein 345038 4548809 FTN_0338 Francisella tularensis subsp. novicida U112 MutT/nudix family protein YP_897998.1 344391 D 401614 CDS YP_897999.1 118496949 4548810 345056..345409 1 NC_008601.1 arsenate reductase 345409 4548810 FTN_0339 Francisella tularensis subsp. novicida U112 arsenate reductase YP_897999.1 345056 D 401614 CDS YP_898000.1 118496950 4548811 complement(345433..345768) 1 NC_008601.1 hypothetical protein 345768 4548811 FTN_0340 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898000.1 345433 R 401614 CDS YP_898001.1 118496951 4548812 complement(345945..346190) 1 NC_008601.1 hypothetical protein 346190 4548812 FTN_0341 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898001.1 345945 R 401614 CDS YP_898002.1 118496952 4548813 complement(346272..347585) 1 NC_008601.1 permease 347585 4548813 FTN_0342 Francisella tularensis subsp. novicida U112 permease YP_898002.1 346272 R 401614 CDS YP_898003.1 118496953 4548814 complement(347652..349238) 1 NC_008601.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 349238 4548814 FTN_0343 Francisella tularensis subsp. novicida U112 aspartate aminotransferase YP_898003.1 347652 R 401614 CDS YP_898004.1 118496954 4548815 complement(349251..350966) 1 NC_008601.1 aspartate:alanine exchanger (AAE) family protein 350966 4548815 FTN_0344 Francisella tularensis subsp. novicida U112 aspartate:alanine exchanger (AAE) family protein YP_898004.1 349251 R 401614 CDS YP_898005.1 118496955 4548816 complement(351041..352147) 1 NC_008601.1 SMF family DNA uptake protein 352147 4548816 FTN_0345 Francisella tularensis subsp. novicida U112 SMF family DNA uptake protein YP_898005.1 351041 R 401614 CDS YP_898006.1 118496956 4548817 complement(352147..353400) 1 NC_008601.1 OmpA family protein 353400 4548817 FTN_0346 Francisella tularensis subsp. novicida U112 OmpA family protein YP_898006.1 352147 R 401614 CDS YP_898007.1 118496957 4548818 353592..354056 1 NC_008601.1 FKBP-type peptidyl-prolyl cis-trans isomerase 354056 fkpB 4548818 fkpB Francisella tularensis subsp. novicida U112 FKBP-type peptidyl-prolyl cis-trans isomerase YP_898007.1 353592 D 401614 CDS YP_898008.1 118496958 4548819 354037..354999 1 NC_008601.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 354999 ispH 4548819 ispH Francisella tularensis subsp. novicida U112 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_898008.1 354037 D 401614 CDS YP_898009.1 118496959 4548330 355001..355363 1 NC_008601.1 chorismate mutase 355363 aroH 4548330 aroH Francisella tularensis subsp. novicida U112 chorismate mutase YP_898009.1 355001 D 401614 CDS YP_898010.1 118496960 4548331 355372..356193 1 NC_008601.1 CDP-alcohol phosphatidyltransferase 356193 pssA 4548331 pssA Francisella tularensis subsp. novicida U112 CDP-alcohol phosphatidyltransferase YP_898010.1 355372 D 401614 CDS YP_898011.1 118496961 4548332 complement(356198..356422) 1 NC_008601.1 hypothetical protein 356422 4548332 FTN_0351 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898011.1 356198 R 401614 CDS YP_898012.1 118496962 4548333 356574..357281 1 NC_008601.1 TolQ protein 357281 tolQ 4548333 tolQ Francisella tularensis subsp. novicida U112 TolQ protein YP_898012.1 356574 D 401614 CDS YP_898013.1 118496963 4548334 357297..357737 1 NC_008601.1 TolR protein 357737 tolR 4548334 tolR Francisella tularensis subsp. novicida U112 TolR protein YP_898013.1 357297 D 401614 CDS YP_898014.1 118496964 4548335 357724..358635 1 NC_008601.1 group A colicin translocation protein TolA 358635 tolA 4548335 tolA Francisella tularensis subsp. novicida U112 group A colicin translocation protein TolA YP_898014.1 357724 D 401614 CDS YP_898015.1 118496965 4548336 358647..359954 1 NC_008601.1 group A colicin translocation protein TolB 359954 tolB 4548336 tolB Francisella tularensis subsp. novicida U112 group A colicin translocation protein TolB YP_898015.1 358647 D 401614 CDS YP_898016.1 118496966 4548337 359964..360209 1 NC_008601.1 hypothetical protein 360209 4548337 FTN_0356 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898016.1 359964 D 401614 CDS YP_898017.1 118496967 4548338 360228..360851 1 NC_008601.1 OmpA family peptidoglycan-associated lipoprotein 360851 pal 4548338 pal Francisella tularensis subsp. novicida U112 OmpA family peptidoglycan-associated lipoprotein YP_898017.1 360228 D 401614 CDS YP_898018.1 118496968 4548339 360958..362277 1 NC_008601.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase 362277 rimO 4548339 rimO Francisella tularensis subsp. novicida U112 ribosomal protein S12 methylthiotransferase YP_898018.1 360958 D 401614 CDS YP_898019.1 118496969 4548340 362380..363102 1 NC_008601.1 short-chain alcohol dehydrogenase 363102 4548340 FTN_0359 Francisella tularensis subsp. novicida U112 short-chain alcohol dehydrogenase YP_898019.1 362380 D 401614 CDS YP_898020.1 118496970 4548341 363126..363356 1 NC_008601.1 hypothetical protein 363356 4548341 FTN_0360 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898020.1 363126 D 401614 CDS YP_898021.1 118496971 4548342 363337..364836 1 NC_008601.1 deoxyribodipyrimidine photolyase 364836 4548342 FTN_0361 Francisella tularensis subsp. novicida U112 deoxyribodipyrimidine photolyase YP_898021.1 363337 D 401614 CDS YP_898022.1 118496972 4548343 364836..366365 1 NC_008601.1 deoxyribodipyrimidine photolyase-like protein 366365 4548343 FTN_0362 Francisella tularensis subsp. novicida U112 deoxyribodipyrimidine photolyase-like protein YP_898022.1 364836 D 401614 CDS YP_898023.1 118496973 4548344 366625..367554 1 NC_008601.1 sodium bile acid symporter family protein 367554 4548344 FTN_0363 Francisella tularensis subsp. novicida U112 sodium bile acid symporter family protein YP_898023.1 366625 D 401614 CDS YP_898024.1 118496974 4548345 367604..368227 1 NC_008601.1 hypothetical protein 368227 4548345 FTN_0364 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898024.1 367604 D 401614 CDS YP_898025.1 118496975 4548346 368251..369009 1 NC_008601.1 hypothetical protein 369009 4548346 FTN_0365 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898025.1 368251 D 401614 CDS YP_898026.1 118496976 4548095 369322..370557 1 NC_008601.1 phage integrase 370557 4548095 FTN_0367 Francisella tularensis subsp. novicida U112 phage integrase YP_898026.1 369322 D 401614 CDS YP_898027.1 118496977 4548096 371729..372253 1 NC_008601.1 hypothetical protein 372253 4548096 FTN_0368 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898027.1 371729 D 401614 CDS YP_898028.1 118496978 4548097 372857..373087 1 NC_008601.1 hypothetical protein 373087 4548097 FTN_0369 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898028.1 372857 D 401614 CDS YP_898029.1 118496979 4548098 373090..373368 1 NC_008601.1 hypothetical protein 373368 4548098 FTN_0370 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898029.1 373090 D 401614 CDS YP_898030.1 118496980 4548099 373472..374329 1 NC_008601.1 hypothetical protein 374329 4548099 FTN_0371 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898030.1 373472 D 401614 CDS YP_898031.1 118496981 4548100 374491..374709 1 NC_008601.1 AlpA family regulatory protein 374709 4548100 FTN_0372 Francisella tularensis subsp. novicida U112 AlpA family regulatory protein YP_898031.1 374491 D 401614 CDS YP_898032.1 118496982 4548101 374890..376086 1 NC_008601.1 phage integrase 376086 4548101 FTN_0373 Francisella tularensis subsp. novicida U112 phage integrase YP_898032.1 374890 D 401614 CDS YP_898033.1 118496983 4548102 376108..376317 1 NC_008601.1 hypothetical protein 376317 4548102 FTN_0374 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898033.1 376108 D 401614 CDS YP_898034.1 118496984 4548103 376636..377253 1 NC_008601.1 hypothetical protein 377253 4548103 FTN_0375 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898034.1 376636 D 401614 CDS YP_898035.1 118496985 4548105 379010..380464 1 NC_008601.1 hypothetical protein 380464 4548105 FTN_0378 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898035.1 379010 D 401614 CDS YP_898036.1 118496986 4548106 380755..381129 1 NC_008601.1 hypothetical protein 381129 4548106 FTN_0379 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898036.1 380755 D 401614 CDS YP_898037.1 118496987 4548107 381374..381619 1 NC_008601.1 hypothetical protein 381619 4548107 FTN_0380 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898037.1 381374 D 401614 CDS YP_898038.1 118496988 4548108 382197..383183 1 NC_008601.1 hypothetical protein 383183 4548108 FTN_0381 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898038.1 382197 D 401614 CDS YP_898039.1 118496989 4548109 383357..384595 1 NC_008601.1 arsenite-antimonite (ArsB) efflux family protein 384595 4548109 FTN_0382 Francisella tularensis subsp. novicida U112 arsenite-antimonite (ArsB) efflux family protein YP_898039.1 383357 D 401614 CDS YP_898040.1 118496990 4548110 complement(384608..384997) 1 NC_008601.1 hypothetical protein 384997 4548110 FTN_0383 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898040.1 384608 R 401614 CDS YP_898041.1 118496991 4548111 complement(385017..385376) 1 NC_008601.1 hypothetical protein 385376 4548111 FTN_0384 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898041.1 385017 R 401614 CDS YP_898042.1 118496992 4548112 complement(385390..386244) 1 NC_008601.1 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; 4-hydroxybenzoate polyprenyltransferase 386244 ubiA 4548112 ubiA Francisella tularensis subsp. novicida U112 4-hydroxybenzoate polyprenyltransferase YP_898042.1 385390 R 401614 CDS YP_898043.1 118496993 4548113 complement(386247..386753) 1 NC_008601.1 chorismate pyruvate lyase 386753 ubiC 4548113 ubiC Francisella tularensis subsp. novicida U112 chorismate pyruvate lyase YP_898043.1 386247 R 401614 CDS YP_898044.1 118496994 4547588 386852..387559 1 NC_008601.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 387559 rph 4547588 rph Francisella tularensis subsp. novicida U112 ribonuclease PH YP_898044.1 386852 D 401614 CDS YP_898045.1 118496995 4547589 complement(387613..387936) 1 NC_008601.1 hypothetical protein 387936 4547589 FTN_0388 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898045.1 387613 R 401614 CDS YP_898046.1 118496996 4547590 complement(388041..388991) 1 NC_008601.1 Type IV pili, pilus assembly protein 388991 4547590 FTN_0389 Francisella tularensis subsp. novicida U112 Type IV pili, pilus assembly protein YP_898046.1 388041 R 401614 CDS YP_898047.1 118496997 4547591 complement(389096..390163) 1 NC_008601.1 putative metalloprotease; heat shock protein HtpX 390163 htpX 4547591 htpX Francisella tularensis subsp. novicida U112 heat shock protein HtpX YP_898047.1 389096 R 401614 CDS YP_898048.1 118496998 4547592 complement(390167..390742) 1 NC_008601.1 LemA-like protein 390742 4547592 FTN_0391 Francisella tularensis subsp. novicida U112 LemA-like protein YP_898048.1 390167 R 401614 CDS YP_898049.1 118496999 4547593 complement(390790..391710) 1 NC_008601.1 LysR family transcriptional regulator 391710 4547593 FTN_0392 Francisella tularensis subsp. novicida U112 LysR family transcriptional regulator YP_898049.1 390790 R 401614 CDS YP_898050.1 118497000 4547594 391849..392904 1 NC_008601.1 hypothetical protein 392904 4547594 FTN_0393 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898050.1 391849 D 401614 CDS YP_898051.1 118497001 4547595 complement(392906..395071) 1 NC_008601.1 heavy metal cation transport ATPase 395071 4547595 FTN_0394 Francisella tularensis subsp. novicida U112 heavy metal cation transport ATPase YP_898051.1 392906 R 401614 CDS YP_898052.1 118497002 4547596 complement(395068..395433) 1 NC_008601.1 ArsR family transcriptional regulator 395433 4547596 FTN_0395 Francisella tularensis subsp. novicida U112 ArsR family transcriptional regulator YP_898052.1 395068 R 401614 CDS YP_898053.1 118497003 4547597 395576..396229 1 NC_008601.1 hypothetical protein 396229 4547597 FTN_0396 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898053.1 395576 D 401614 CDS YP_898054.1 118497004 4547598 396549..397547 1 NC_008601.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 397547 gpsA 4547598 gpsA Francisella tularensis subsp. novicida U112 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase YP_898054.1 396549 D 401614 CDS YP_898055.1 118497005 4547599 complement(397548..398084) 1 NC_008601.1 hypothetical protein 398084 4547599 FTN_0398 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898055.1 397548 R 401614 CDS YP_898056.1 118497006 4547600 complement(398089..399459) 1 NC_008601.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 399459 radA 4547600 radA Francisella tularensis subsp. novicida U112 DNA repair protein RadA YP_898056.1 398089 R 401614 CDS YP_898057.1 118497007 4547601 complement(399467..400237) 1 NC_008601.1 hypothetical protein 400237 4547601 FTN_0400 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898057.1 399467 R 401614 CDS YP_898058.1 118497008 4547602 complement(400234..400833) 1 NC_008601.1 hypothetical protein 400833 4547602 FTN_0401 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898058.1 400234 R 401614 CDS YP_898059.1 118497009 4547603 complement(400836..401894) 1 NC_008601.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 401894 aroC 4547603 aroC Francisella tularensis subsp. novicida U112 chorismate synthase YP_898059.1 400836 R 401614 CDS YP_898060.1 118497010 4547604 complement(402035..402688) 1 NC_008601.1 hypothetical protein 402688 4547604 FTN_0403 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898060.1 402035 R 401614 CDS YP_898061.1 118497011 4547605 complement(402707..403219) 1 NC_008601.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 403219 4547605 FTN_0404 Francisella tularensis subsp. novicida U112 methionine sulfoxide reductase B YP_898061.1 402707 R 401614 CDS YP_898062.1 118497012 4547606 403380..403937 1 NC_008601.1 superoxide dismutase 403937 sodC 4547606 sodC Francisella tularensis subsp. novicida U112 superoxide dismutase YP_898062.1 403380 D 401614 CDS YP_898063.1 118497013 4547721 403941..404732 1 NC_008601.1 sterol desaturase 404732 4547721 FTN_0406 Francisella tularensis subsp. novicida U112 sterol desaturase YP_898063.1 403941 D 401614 CDS YP_898064.1 118497014 4547722 complement(404707..406101) 1 NC_008601.1 amino acid ABC transporter permease 406101 4547722 FTN_0407 Francisella tularensis subsp. novicida U112 amino acid ABC transporter permease YP_898064.1 404707 R 401614 CDS YP_898065.1 118497015 4547723 406141..406614 1 NC_008601.1 mannose-6-phosphate isomerase 406614 4547723 FTN_0408 Francisella tularensis subsp. novicida U112 mannose-6-phosphate isomerase YP_898065.1 406141 D 401614 CDS YP_898066.1 118497016 4547724 406706..407818 1 NC_008601.1 Zn-dependent alcohol dehydrogenase 407818 adhC 4547724 adhC Francisella tularensis subsp. novicida U112 Zn-dependent alcohol dehydrogenase YP_898066.1 406706 D 401614 CDS YP_898067.1 118497017 4547725 complement(407867..409057) 1 NC_008601.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 409057 4547725 FTN_0410 Francisella tularensis subsp. novicida U112 aspartate aminotransferase YP_898067.1 407867 R 401614 CDS YP_898068.1 118497018 4547726 409260..410147 1 NC_008601.1 cation transporter 410147 4547726 FTN_0411 Francisella tularensis subsp. novicida U112 cation transporter YP_898068.1 409260 D 401614 CDS YP_898069.1 118497019 4547727 410233..411882 1 NC_008601.1 DNA repair protein 411882 recN 4547727 recN Francisella tularensis subsp. novicida U112 DNA repair protein YP_898069.1 410233 D 401614 CDS YP_898070.1 118497020 4547728 complement(412117..413349) 1 NC_008601.1 Type IV pili, pilus assembly protein 413349 pilV 4547728 pilV Francisella tularensis subsp. novicida U112 Type IV pili, pilus assembly protein YP_898070.1 412117 R 401614 CDS YP_898071.1 118497021 4547729 complement(413582..414019) 1 NC_008601.1 Type IV pili, pilus assembly protein 414019 4547729 FTN_0414 Francisella tularensis subsp. novicida U112 Type IV pili, pilus assembly protein YP_898071.1 413582 R 401614 CDS YP_898072.1 118497022 4547730 complement(414149..414556) 1 NC_008601.1 Type IV pili, pilus assembly protein 414556 pilA 4547730 pilA Francisella tularensis subsp. novicida U112 Type IV pili, pilus assembly protein YP_898072.1 414149 R 401614 CDS YP_898073.1 118497023 4547731 414941..415660 1 NC_008601.1 lipid A 1-phosphatase 415660 lpxE 4547731 lpxE Francisella tularensis subsp. novicida U112 lipid A 1-phosphatase YP_898073.1 414941 D 401614 CDS YP_898074.1 118497024 4547732 415800..416648 1 NC_008601.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 416648 folD 4547732 folD Francisella tularensis subsp. novicida U112 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_898074.1 415800 D 401614 CDS YP_898075.1 118497025 4547733 416811..417101 1 NC_008601.1 endonuclease 417101 4547733 FTN_0418 Francisella tularensis subsp. novicida U112 endonuclease YP_898075.1 416811 D 401614 CDS YP_898076.1 118497026 4547734 417319..418362 1 NC_008601.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 418362 purM 4547734 purM Francisella tularensis subsp. novicida U112 phosphoribosylaminoimidazole synthetase YP_898076.1 417319 D 401614 CDS YP_898077.1 118497027 4547735 418362..420674 1 NC_008601.1 SAICAR synthetase/phosphoribosylamine-glycine ligase 420674 4547735 FTN_0420 Francisella tularensis subsp. novicida U112 SAICAR synthetase/phosphoribosylamine-glycine ligase YP_898077.1 418362 D 401614 CDS YP_898078.1 118497028 4547736 420678..421253 1 NC_008601.1 phosphoribosylglycinamide formyltransferase 421253 purN 4547736 purN Francisella tularensis subsp. novicida U112 phosphoribosylglycinamide formyltransferase YP_898078.1 420678 D 401614 CDS YP_898079.1 118497029 4547737 421370..421861 1 NC_008601.1 N5-carboxyaminoimidazole ribonucleotide mutase 421861 purE 4547737 purE Francisella tularensis subsp. novicida U112 N5-carboxyaminoimidazole ribonucleotide mutase YP_898079.1 421370 D 401614 CDS YP_898080.1 118497030 4547738 421865..422962 1 NC_008601.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 422962 purK 4547738 purK Francisella tularensis subsp. novicida U112 phosphoribosylaminoimidazole carboxylase ATPase subunit YP_898080.1 421865 D 401614 CDS YP_898081.1 118497031 4547739 complement(422959..423312) 1 NC_008601.1 hypothetical protein 423312 4547739 FTN_0424 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898081.1 422959 R 401614 CDS YP_898082.1 118497032 4547740 complement(423393..425399) 1 NC_008601.1 oligopeptidase A 425399 prlC 4547740 prlC Francisella tularensis subsp. novicida U112 oligopeptidase A YP_898082.1 423393 R 401614 CDS YP_898083.1 118497033 4548076 425491..425862 1 NC_008601.1 hypothetical protein 425862 4548076 FTN_0426 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898083.1 425491 D 401614 CDS YP_898084.1 118497034 4548077 425944..426393 1 NC_008601.1 hypothetical protein 426393 4548077 FTN_0427 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898084.1 425944 D 401614 CDS YP_898085.1 118497035 4548078 426551..427030 1 NC_008601.1 hypothetical protein 427030 4548078 FTN_0428 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898085.1 426551 D 401614 CDS YP_898086.1 118497036 4548079 427130..427633 1 NC_008601.1 hypothetical protein 427633 4548079 FTN_0429 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898086.1 427130 D 401614 CDS YP_898087.1 118497037 4548080 427666..428133 1 NC_008601.1 hypothetical protein 428133 4548080 FTN_0430 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898087.1 427666 D 401614 CDS YP_898088.1 118497038 4548081 428206..429648 1 NC_008601.1 hypothetical protein 429648 4548081 FTN_0431 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898088.1 428206 D 401614 CDS YP_898089.1 118497039 4548082 complement(429702..431996) 1 NC_008601.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining; maintains net negative superhelicity; DNA topoisomerase I 431996 topA 4548082 topA Francisella tularensis subsp. novicida U112 DNA topoisomerase I YP_898089.1 429702 R 401614 CDS YP_898090.1 118497040 4548083 432195..432836 1 NC_008601.1 chmomosome partition protein A 432836 parA 4548083 parA Francisella tularensis subsp. novicida U112 chmomosome partition protein A YP_898090.1 432195 D 401614 CDS YP_898091.1 118497041 4548084 432829..433743 1 NC_008601.1 chromosome partition protein B 433743 parB 4548084 parB Francisella tularensis subsp. novicida U112 chromosome partition protein B YP_898091.1 432829 D 401614 CDS YP_898092.1 118497042 4548085 433757..434464 1 NC_008601.1 glutamine amidotransferase 434464 4548085 FTN_0435 Francisella tularensis subsp. novicida U112 glutamine amidotransferase YP_898092.1 433757 D 401614 CDS YP_898093.1 118497043 4548086 434467..435348 1 NC_008601.1 hypothetical protein 435348 4548086 FTN_0436 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898093.1 434467 D 401614 CDS YP_898094.1 118497044 4548087 435345..435935 1 NC_008601.1 HD superfamily hydrolase 435935 4548087 FTN_0437 Francisella tularensis subsp. novicida U112 HD superfamily hydrolase YP_898094.1 435345 D 401614 CDS YP_898095.1 118497045 4548088 complement(435995..436615) 1 NC_008601.1 ribosomal large subunit methyltransferase J 436615 rrmJ 4548088 rrmJ Francisella tularensis subsp. novicida U112 ribosomal large subunit methyltransferase J YP_898095.1 435995 R 401614 CDS YP_898096.1 118497046 4548089 436773..437240 1 NC_008601.1 hypothetical protein 437240 4548089 FTN_0439 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898096.1 436773 D 401614 CDS YP_898097.1 118497047 4548090 complement(437235..437720) 1 NC_008601.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 437720 lspA 4548090 lspA Francisella tularensis subsp. novicida U112 lipoprotein signal peptidase YP_898097.1 437235 R 401614 CDS YP_898098.1 118497048 4548091 complement(437707..440514) 1 NC_008601.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 440514 ileS 4548091 ileS Francisella tularensis subsp. novicida U112 isoleucyl-tRNA synthetase YP_898098.1 437707 R 401614 CDS YP_898099.1 118497049 4548092 complement(440607..441527) 1 NC_008601.1 riboflavin biosynthesis protein RibF 441527 ribF 4548092 ribF Francisella tularensis subsp. novicida U112 riboflavin biosynthesis protein RibF YP_898099.1 440607 R 401614 CDS YP_898100.1 118497050 4548093 441678..443492 1 NC_008601.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase 443492 maeA 4548093 maeA Francisella tularensis subsp. novicida U112 malate dehydrogenase YP_898100.1 441678 D 401614 CDS YP_898101.1 118497051 4548094 443654..445327 1 NC_008601.1 membrane protein 445327 4548094 FTN_0444 Francisella tularensis subsp. novicida U112 membrane protein YP_898101.1 443654 D 401614 CDS YP_898102.1 118497052 4548609 445344..446789 1 NC_008601.1 hypothetical protein 446789 4548609 FTN_0445 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898102.1 445344 D 401614 CDS YP_898103.1 118497053 4548610 446993..448390 1 NC_008601.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 448390 engA 4548610 engA Francisella tularensis subsp. novicida U112 GTP-binding protein EngA YP_898103.1 446993 D 401614 CDS YP_898104.1 118497054 4548611 448359..449663 1 NC_008601.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase 449663 murA 4548611 murA Francisella tularensis subsp. novicida U112 UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_898104.1 448359 D 401614 CDS YP_898105.1 118497055 4548612 449671..450519 1 NC_008601.1 UDP-N-acetylenolpyruvoylglucosamine reductase 450519 murB 4548612 murB Francisella tularensis subsp. novicida U112 UDP-N-acetylenolpyruvoylglucosamine reductase YP_898105.1 449671 D 401614 CDS YP_898106.1 118497056 4548613 450598..451473 1 NC_008601.1 hypothetical protein 451473 4548613 FTN_0449 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898106.1 450598 D 401614 CDS YP_898107.1 118497057 4548614 complement(451475..452251) 1 NC_008601.1 hypothetical protein 452251 4548614 FTN_0450 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898107.1 451475 R 401614 CDS YP_898108.1 118497058 4548615 complement(452274..454379) 1 NC_008601.1 signal transduction protein 454379 4548615 FTN_0451 Francisella tularensis subsp. novicida U112 signal transduction protein YP_898108.1 452274 R 401614 CDS YP_898109.1 118497059 4548616 454529..455932 1 NC_008601.1 hypothetical protein 455932 4548616 FTN_0452 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898109.1 454529 D 401614 CDS YP_898110.1 118497060 4548617 455936..457252 1 NC_008601.1 glycosyl transferase family protein 457252 4548617 FTN_0453 Francisella tularensis subsp. novicida U112 glycosyl transferase family protein YP_898110.1 455936 D 401614 CDS YP_898111.1 118497061 4548618 457266..458282 1 NC_008601.1 hypothetical protein 458282 4548618 FTN_0454 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898111.1 457266 D 401614 CDS YP_898112.1 118497062 4548619 458374..461274 1 NC_008601.1 CheB methylesterase/CheR methyltransferase 461274 4548619 FTN_0455 Francisella tularensis subsp. novicida U112 CheB methylesterase/CheR methyltransferase YP_898112.1 458374 D 401614 CDS YP_898113.1 118497063 4548620 461255..463573 1 NC_008601.1 signal transduction protein 463573 4548620 FTN_0456 Francisella tularensis subsp. novicida U112 signal transduction protein YP_898113.1 461255 D 401614 CDS YP_898114.1 118497064 4548621 463591..464250 1 NC_008601.1 hypothetical protein 464250 4548621 FTN_0457 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898114.1 463591 D 401614 CDS YP_898115.1 118497065 4548622 complement(464765..465103) 1 NC_008601.1 histidine triad (HIT) family protein 465103 hitA 4548622 hitA Francisella tularensis subsp. novicida U112 histidine triad (HIT) family protein YP_898115.1 464765 R 401614 CDS YP_898116.1 118497066 4548623 complement(465109..466767) 1 NC_008601.1 2-octaprenylphenol hydroxylase 466767 ubiB 4548623 ubiB Francisella tularensis subsp. novicida U112 2-octaprenylphenol hydroxylase YP_898116.1 465109 R 401614 CDS YP_898117.1 118497067 4548624 complement(466760..467347) 1 NC_008601.1 hypothetical protein 467347 4548624 FTN_0460 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898117.1 466760 R 401614 CDS YP_898118.1 118497068 4548625 complement(467349..468101) 1 NC_008601.1 menaquinone biosynthesis methyltransferase 468101 ubiE 4548625 ubiE Francisella tularensis subsp. novicida U112 menaquinone biosynthesis methyltransferase YP_898118.1 467349 R 401614 CDS YP_898119.1 118497069 4548626 468195..469211 1 NC_008601.1 glucose kinase 469211 glk 4548626 glk Francisella tularensis subsp. novicida U112 glucose kinase YP_898119.1 468195 D 401614 CDS YP_898120.1 118497070 4548627 complement(469213..469476) 1 NC_008601.1 hypothetical protein 469476 4548627 FTN_0463 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898120.1 469213 R 401614 CDS YP_898121.1 118497071 4548628 complement(469550..470080) 1 NC_008601.1 intracellular septation protein A family protein 470080 4548628 FTN_0464 Francisella tularensis subsp. novicida U112 intracellular septation protein A family protein YP_898121.1 469550 R 401614 CDS YP_898122.1 118497072 4548224 470141..470755 1 NC_008601.1 Sua5/YciO/YrdC family protein 470755 4548224 FTN_0465 Francisella tularensis subsp. novicida U112 Sua5/YciO/YrdC family protein YP_898122.1 470141 D 401614 CDS YP_898123.1 118497073 4548225 470805..471407 1 NC_008601.1 hypothetical protein 471407 4548225 FTN_0466 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898123.1 470805 D 401614 CDS YP_898124.1 118497074 4548226 complement(471404..472627) 1 NC_008601.1 major facilitator superfamily sugar transporter 472627 4548226 FTN_0467 Francisella tularensis subsp. novicida U112 major facilitator superfamily sugar transporter YP_898124.1 471404 R 401614 CDS YP_898125.1 118497075 4548227 complement(472644..474701) 1 NC_008601.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 474701 metG 4548227 metG Francisella tularensis subsp. novicida U112 methionyl-tRNA synthetase YP_898125.1 472644 R 401614 CDS YP_898126.1 118497076 4548230 complement(475224..475760) 1 NC_008601.1 NADPH-dependent FMN reductase 475760 4548230 FTN_0471 Francisella tularensis subsp. novicida U112 NADPH-dependent FMN reductase YP_898126.1 475224 R 401614 CDS YP_898127.1 118497077 4547455 481348..482235 1 NC_008601.1 hypothetical protein 482235 4547455 FTN_0477 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898127.1 481348 D 401614 CDS YP_898128.1 118497078 4547456 complement(483383..484438) 1 NC_008601.1 hypothetical protein 484438 4547456 FTN_0478 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898128.1 483383 R 401614 CDS YP_898129.1 118497079 4547457 complement(484552..485208) 1 NC_008601.1 M50B family metallopeptidase 485208 4547457 FTN_0479 Francisella tularensis subsp. novicida U112 M50B family metallopeptidase YP_898129.1 484552 R 401614 CDS YP_898130.1 118497080 4547458 486541..486876 1 NC_008601.1 hypothetical protein 486876 4547458 FTN_0480 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898130.1 486541 D 401614 CDS YP_898131.1 118497081 4547459 complement(486849..487700) 1 NC_008601.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase 487700 psd 4547459 psd Francisella tularensis subsp. novicida U112 phosphatidylserine decarboxylase YP_898131.1 486849 R 401614 CDS YP_898132.1 118497082 4547460 487800..488780 1 NC_008601.1 hypothetical protein 488780 4547460 FTN_0482 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898132.1 487800 D 401614 CDS YP_898133.1 118497083 4547461 488789..489832 1 NC_008601.1 NadM-Nudix subfamily; involved in creation of nicotanimide adenine dinucleotide NAD from either biosynthetic or salvage pathways; bifunctional nicotinamide mononucleotide adenylyltransferase/ADP-ribose pyrophosphatase 489832 4547461 FTN_0483 Francisella tularensis subsp. novicida U112 bifunctional nicotinamide mononucleotide adenylyltransferase/ADP-ribose pyrophosphatase YP_898133.1 488789 D 401614 CDS YP_898134.1 118497084 4547462 489846..491213 1 NC_008601.1 UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase 491213 glmU 4547462 glmU Francisella tularensis subsp. novicida U112 UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase YP_898134.1 489846 D 401614 CDS YP_898135.1 118497085 4547463 491234..493072 1 NC_008601.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 493072 glmS 4547463 glmS Francisella tularensis subsp. novicida U112 glucosamine--fructose-6-phosphate aminotransferase YP_898135.1 491234 D 401614 CDS YP_898136.1 118497086 4547464 493144..493677 1 NC_008601.1 acetyltransferase 493677 4547464 FTN_0486 Francisella tularensis subsp. novicida U112 acetyltransferase YP_898136.1 493144 D 401614 CDS YP_898137.1 118497087 4547465 complement(493674..493871) 1 NC_008601.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 493871 rpsU 4547465 rpsU Francisella tularensis subsp. novicida U112 30S ribosomal protein S21 YP_898137.1 493674 R 401614 CDS YP_898138.1 118497088 4547466 complement(493871..494074) 1 NC_008601.1 cold shock protein 494074 cspC 4547466 cspC Francisella tularensis subsp. novicida U112 cold shock protein YP_898138.1 493871 R 401614 CDS YP_898139.1 118497089 4547467 complement(494325..494654) 1 NC_008601.1 hypothetical protein 494654 4547467 FTN_0489 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898139.1 494325 R 401614 CDS YP_898140.1 118497090 4547468 494781..495551 1 NC_008601.1 methionine aminopeptidase 495551 map 4547468 map Francisella tularensis subsp. novicida U112 methionine aminopeptidase YP_898140.1 494781 D 401614 CDS YP_898141.1 118497091 4547469 495553..496401 1 NC_008601.1 hypothetical protein 496401 4547469 FTN_0491 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898141.1 495553 D 401614 CDS YP_898142.1 118497092 4547470 496504..498732 1 NC_008601.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 498732 parC 4547470 parC Francisella tularensis subsp. novicida U112 DNA topoisomerase IV subunit A YP_898142.1 496504 D 401614 CDS YP_898143.1 118497093 4547471 498729..499415 1 NC_008601.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 499415 mtn 4547471 mtn Francisella tularensis subsp. novicida U112 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase YP_898143.1 498729 D 401614 CDS YP_898144.1 118497094 4547472 complement(499402..500001) 1 NC_008601.1 hypothetical protein 500001 4547472 FTN_0494 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898144.1 499402 R 401614 CDS YP_898145.1 118497095 4547473 complement(499994..501112) 1 NC_008601.1 BNR/Asp-box repeat-containing protein 501112 4547473 FTN_0495 Francisella tularensis subsp. novicida U112 BNR/Asp-box repeat-containing protein YP_898145.1 499994 R 401614 CDS YP_898146.1 118497096 4547663 501311..503287 1 NC_008601.1 soluble lytic murein transglycosylase 503287 slt 4547663 slt Francisella tularensis subsp. novicida U112 soluble lytic murein transglycosylase YP_898146.1 501311 D 401614 CDS YP_898147.1 118497097 4547664 complement(503301..503723) 1 NC_008601.1 hypothetical protein 503723 4547664 FTN_0497 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898147.1 503301 R 401614 CDS YP_898148.1 118497098 4547665 504268..505497 1 NC_008601.1 hypothetical protein 505497 4547665 FTN_0498 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898148.1 504268 D 401614 CDS YP_898149.1 118497099 4547666 505748..509227 1 NC_008601.1 DNA polymerase III subunit alpha 509227 dnaE 4547666 dnaE Francisella tularensis subsp. novicida U112 DNA polymerase III subunit alpha YP_898149.1 505748 D 401614 CDS YP_898150.1 118497100 4547667 509303..509938 1 NC_008601.1 peptide deformylase 509938 4547667 FTN_0500 Francisella tularensis subsp. novicida U112 peptide deformylase YP_898150.1 509303 D 401614 CDS YP_898151.1 118497101 4547669 510648..511910 1 NC_008601.1 ABC transporter involved in lipoprotein release, permease component 511910 4547669 FTN_0502 Francisella tularensis subsp. novicida U112 ABC transporter involved in lipoprotein release, permease component YP_898151.1 510648 D 401614 CDS YP_898152.1 118497102 4547670 511903..512598 1 NC_008601.1 ABC transporter ATPase 512598 4547670 FTN_0503 Francisella tularensis subsp. novicida U112 ABC transporter ATPase YP_898152.1 511903 D 401614 CDS YP_898153.1 118497103 4547671 512714..514855 1 NC_008601.1 lysine decarboxylase 514855 4547671 FTN_0504 Francisella tularensis subsp. novicida U112 lysine decarboxylase YP_898153.1 512714 D 401614 CDS YP_898154.1 118497104 4547672 514946..516022 1 NC_008601.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 516022 gcvT 4547672 gcvT Francisella tularensis subsp. novicida U112 glycine cleavage system aminomethyltransferase T YP_898154.1 514946 D 401614 CDS YP_898155.1 118497105 4547673 516080..516463 1 NC_008601.1 glycine cleavage system H protein 516463 gcvH 4547673 gcvH Francisella tularensis subsp. novicida U112 glycine cleavage system H protein YP_898155.1 516080 D 401614 CDS YP_898156.1 118497106 4547674 516528..517895 1 NC_008601.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein; glycine dehydrogenase subunit 1 517895 gcvP1 4547674 gcvP1 Francisella tularensis subsp. novicida U112 glycine dehydrogenase subunit 1 YP_898156.1 516528 D 401614 CDS YP_898157.1 118497107 4547675 517901..519346 1 NC_008601.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein; glycine dehydrogenase subunit 2 519346 gcvP2 4547675 gcvP2 Francisella tularensis subsp. novicida U112 glycine dehydrogenase subunit 2 YP_898157.1 517901 D 401614 CDS YP_898158.1 118497108 4547676 519765..523157 1 NC_008601.1 hypothetical protein 523157 4547676 FTN_0509 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898158.1 519765 D 401614 CDS YP_898159.1 118497109 4547677 523321..523686 1 NC_008601.1 hypothetical protein 523686 4547677 FTN_0510 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898159.1 523321 D 401614 CDS YP_898160.1 118497110 4547678 complement(523814..524659) 1 NC_008601.1 shikimate 5-dehydrogenase 524659 4547678 FTN_0511 Francisella tularensis subsp. novicida U112 shikimate 5-dehydrogenase YP_898160.1 523814 R 401614 CDS YP_898161.1 118497111 4547679 complement(524685..527897) 1 NC_008601.1 pullulanase 527897 glgX 4547679 glgX Francisella tularensis subsp. novicida U112 pullulanase YP_898161.1 524685 R 401614 CDS YP_898162.1 118497112 4547680 complement(527931..529853) 1 NC_008601.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein 529853 glgB 4547680 glgB Francisella tularensis subsp. novicida U112 glycogen branching protein YP_898162.1 527931 R 401614 CDS YP_898163.1 118497113 4547357 530155..531789 1 NC_008601.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 531789 pgm 4547357 pgm Francisella tularensis subsp. novicida U112 phosphoglucomutase YP_898163.1 530155 D 401614 CDS YP_898164.1 118497114 4547358 531823..533094 1 NC_008601.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 533094 glgC 4547358 glgC Francisella tularensis subsp. novicida U112 glucose-1-phosphate adenylyltransferase YP_898164.1 531823 D 401614 CDS YP_898165.1 118497115 4547359 533104..534573 1 NC_008601.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 534573 glgA 4547359 glgA Francisella tularensis subsp. novicida U112 glycogen synthase YP_898165.1 533104 D 401614 CDS YP_898166.1 118497116 4547360 534678..536951 1 NC_008601.1 glycogen phosphorylase 536951 glgP 4547360 glgP Francisella tularensis subsp. novicida U112 glycogen phosphorylase YP_898166.1 534678 D 401614 CDS YP_898167.1 118497117 4547361 536994..538457 1 NC_008601.1 amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 538457 malQ 4547361 malQ Francisella tularensis subsp. novicida U112 4-alpha-glucanotransferase YP_898167.1 536994 D 401614 CDS YP_898168.1 118497118 4547362 538549..539439 1 NC_008601.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 539439 glyQ 4547362 glyQ Francisella tularensis subsp. novicida U112 glycyl-tRNA synthetase subunit alpha YP_898168.1 538549 D 401614 CDS YP_898169.1 118497119 4547363 539650..541089 1 NC_008601.1 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 541089 murE 4547363 murE Francisella tularensis subsp. novicida U112 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_898169.1 539650 D 401614 CDS YP_898170.1 118497120 4547364 541170..541529 1 NC_008601.1 hypothetical protein 541529 4547364 FTN_0521 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898170.1 541170 D 401614 CDS YP_898171.1 118497121 4547365 541881..543239 1 NC_008601.1 UDP-N--acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate-D-alanyl-D-alanyl ligase 543239 murF 4547365 murF Francisella tularensis subsp. novicida U112 UDP-N--acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate-D-alanyl-D-alanyl ligase YP_898171.1 541881 D 401614 CDS YP_898172.1 118497122 4547366 543248..544066 1 NC_008601.1 hypothetical protein 544066 4547366 FTN_0523 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898172.1 543248 D 401614 CDS YP_898173.1 118497123 4547367 complement(544116..545216) 1 NC_008601.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 545216 asd 4547367 asd Francisella tularensis subsp. novicida U112 aspartate-semialdehyde dehydrogenase YP_898173.1 544116 R 401614 CDS YP_898174.1 118497124 4547368 545312..547732 1 NC_008601.1 aspartate kinase I/homoserine dehydrogenase I 547732 thrA 4547368 thrA Francisella tularensis subsp. novicida U112 aspartate kinase I/homoserine dehydrogenase I YP_898174.1 545312 D 401614 CDS YP_898175.1 118497125 4547369 547735..548688 1 NC_008601.1 homoserine kinase 548688 thrB 4547369 thrB Francisella tularensis subsp. novicida U112 homoserine kinase YP_898175.1 547735 D 401614 CDS YP_898176.1 118497126 4547370 548701..549990 1 NC_008601.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 549990 thrC 4547370 thrC Francisella tularensis subsp. novicida U112 threonine synthase YP_898176.1 548701 D 401614 CDS YP_898177.1 118497127 4547371 complement(550018..550740) 1 NC_008601.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase 550740 lpxH 4547371 lpxH Francisella tularensis subsp. novicida U112 UDP-2,3-diacylglucosamine hydrolase YP_898177.1 550018 R 401614 CDS YP_898178.1 118497128 4547372 complement(550730..551356) 1 NC_008601.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 551356 pyrE 4547372 pyrE Francisella tularensis subsp. novicida U112 orotate phosphoribosyltransferase YP_898178.1 550730 R 401614 CDS YP_898179.1 118497129 4547373 551516..552886 1 NC_008601.1 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 552886 mpl 4547373 mpl Francisella tularensis subsp. novicida U112 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase YP_898179.1 551516 D 401614 CDS YP_898180.1 118497130 4547374 552883..553629 1 NC_008601.1 tRNA/rRNA methyltransferase 553629 yjfH 4547374 yjfH Francisella tularensis subsp. novicida U112 tRNA/rRNA methyltransferase YP_898180.1 552883 D 401614 CDS YP_898181.1 118497131 4547375 complement(553645..554289) 1 NC_008601.1 hypothetical protein 554289 4547375 FTN_0532 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898181.1 553645 R 401614 CDS YP_898182.1 118497132 4547376 complement(554319..555512) 1 NC_008601.1 drug:H+ antiporter-1 (DHA1) family protein 555512 4547376 FTN_0533 Francisella tularensis subsp. novicida U112 drug:H+ antiporter-1 (DHA1) family protein YP_898182.1 554319 R 401614 CDS YP_898183.1 118497133 4547511 555784..556827 1 NC_008601.1 hypothetical protein 556827 4547511 FTN_0534 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898183.1 555784 D 401614 CDS YP_898184.1 118497134 4547512 556910..558136 1 NC_008601.1 drug:H+ antiporter-1 (DHA1) family protein 558136 4547512 FTN_0535 Francisella tularensis subsp. novicida U112 drug:H+ antiporter-1 (DHA1) family protein YP_898184.1 556910 D 401614 CDS YP_898185.1 118497135 4547513 558170..560011 1 NC_008601.1 drug resistance ATPase-1 family protein 560011 yjjK 4547513 yjjK Francisella tularensis subsp. novicida U112 drug resistance ATPase-1 family protein YP_898185.1 558170 D 401614 CDS YP_898186.1 118497136 4547514 560098..561510 1 NC_008601.1 proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter 561510 4547514 FTN_0537 Francisella tularensis subsp. novicida U112 proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter YP_898186.1 560098 D 401614 CDS YP_898187.1 118497137 4547515 complement(561535..562995) 1 NC_008601.1 hypothetical protein 562995 4547515 FTN_0538 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898187.1 561535 R 401614 CDS YP_898188.1 118497138 4547516 complement(563016..564662) 1 NC_008601.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 564662 glnS 4547516 glnS Francisella tularensis subsp. novicida U112 glutaminyl-tRNA synthetase YP_898188.1 563016 R 401614 CDS YP_898189.1 118497139 4547517 564807..566399 1 NC_008601.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 566399 pckA 4547517 pckA Francisella tularensis subsp. novicida U112 phosphoenolpyruvate carboxykinase YP_898189.1 564807 D 401614 CDS YP_898190.1 118497140 4547518 566474..567571 1 NC_008601.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 567571 mraY 4547518 mraY Francisella tularensis subsp. novicida U112 phospho-N-acetylmuramoyl-pentapeptide- transferase YP_898190.1 566474 D 401614 CDS YP_898191.1 118497141 4547519 567571..568824 1 NC_008601.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase 568824 murD 4547519 murD Francisella tularensis subsp. novicida U112 UDP-N-acetylmuramoylalanine--D-glutamate ligase YP_898191.1 567571 D 401614 CDS YP_898192.1 118497142 4547520 568834..570039 1 NC_008601.1 cell division protein FtsW 570039 ftsW 4547520 ftsW Francisella tularensis subsp. novicida U112 cell division protein FtsW YP_898192.1 568834 D 401614 CDS YP_898193.1 118497143 4547521 complement(570047..570853) 1 NC_008601.1 hypothetical protein 570853 4547521 FTN_0544 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898193.1 570047 R 401614 CDS YP_898194.1 118497144 4547522 570952..571908 1 NC_008601.1 glycosyl transferase 571908 4547522 FTN_0545 Francisella tularensis subsp. novicida U112 glycosyl transferase YP_898194.1 570952 D 401614 CDS YP_898195.1 118497145 4547523 complement(572301..574064) 1 NC_008601.1 dolichyl-phosphate-mannose-protein mannosyltransferase family protein 574064 4547523 FTN_0546 Francisella tularensis subsp. novicida U112 dolichyl-phosphate-mannose-protein mannosyltransferase family protein YP_898195.1 572301 R 401614 CDS YP_898196.1 118497146 4547524 complement(574156..574419) 1 NC_008601.1 hypothetical protein 574419 4547524 FTN_0547 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898196.1 574156 R 401614 CDS YP_898197.1 118497147 4547525 complement(574440..574754) 1 NC_008601.1 hypothetical protein 574754 4547525 FTN_0548 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898197.1 574440 R 401614 CDS YP_898198.1 118497148 4547526 574840..575472 1 NC_008601.1 stringent starvation protein A 575472 sspA 4547526 sspA Francisella tularensis subsp. novicida U112 stringent starvation protein A YP_898198.1 574840 D 401614 CDS YP_898199.1 118497149 4547527 575484..576500 1 NC_008601.1 SohB; periplasmic protein; member of the peptidase S49 family; putative periplasmic protease 576500 sohB 4547527 sohB Francisella tularensis subsp. novicida U112 putative periplasmic protease YP_898199.1 575484 D 401614 CDS YP_898200.1 118497150 4547528 576508..577419 1 NC_008601.1 DNA polymerase III, delta prime subunit 577419 holB 4547528 holB Francisella tularensis subsp. novicida U112 DNA polymerase III, delta prime subunit YP_898200.1 576508 D 401614 CDS YP_898201.1 118497151 4547529 577430..577708 1 NC_008601.1 RNA-binding protein 577708 yhbY 4547529 yhbY Francisella tularensis subsp. novicida U112 RNA-binding protein YP_898201.1 577430 D 401614 CDS YP_898202.1 118497152 4548458 577716..578690 1 NC_008601.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 578690 hemB 4548458 hemB Francisella tularensis subsp. novicida U112 delta-aminolevulinic acid dehydratase YP_898202.1 577716 D 401614 CDS YP_898203.1 118497153 4548459 578694..579161 1 NC_008601.1 RNA methyltransferase 579161 4548459 FTN_0554 Francisella tularensis subsp. novicida U112 RNA methyltransferase YP_898203.1 578694 D 401614 CDS YP_898204.1 118497154 4548460 579267..580331 1 NC_008601.1 periplasmic L-asparaginase II 580331 ansB 4548460 ansB Francisella tularensis subsp. novicida U112 periplasmic L-asparaginase II YP_898204.1 579267 D 401614 CDS YP_898205.1 118497155 4548461 580679..581242 1 NC_008601.1 hypothetical protein 581242 4548461 FTN_0556 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898205.1 580679 D 401614 CDS YP_898206.1 118497156 4548462 complement(581293..583038) 1 NC_008601.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 583038 argS 4548462 argS Francisella tularensis subsp. novicida U112 arginyl-tRNA synthetase YP_898206.1 581293 R 401614 CDS YP_898207.1 118497157 4548463 583164..585770 1 NC_008601.1 organic solvent tolerance protein, OstA 585770 ostA1 4548463 ostA1 Francisella tularensis subsp. novicida U112 organic solvent tolerance protein, OstA YP_898207.1 583164 D 401614 CDS YP_898208.1 118497158 4548464 585770..587179 1 NC_008601.1 peptidyl-prolyl cis-trans isomerase 587179 4548464 FTN_0559 Francisella tularensis subsp. novicida U112 peptidyl-prolyl cis-trans isomerase YP_898208.1 585770 D 401614 CDS YP_898209.1 118497159 4548465 587181..587969 1 NC_008601.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 587969 ksgA 4548465 ksgA Francisella tularensis subsp. novicida U112 dimethyladenosine transferase YP_898209.1 587181 D 401614 CDS YP_898210.1 118497160 4548466 587981..588808 1 NC_008601.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 588808 apaH 4548466 apaH Francisella tularensis subsp. novicida U112 diadenosine tetraphosphatase YP_898210.1 587981 D 401614 CDS YP_898211.1 118497161 4548467 588812..589249 1 NC_008601.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 589249 aroD 4548467 aroD Francisella tularensis subsp. novicida U112 3-dehydroquinate dehydratase YP_898211.1 588812 D 401614 CDS YP_898212.1 118497162 4548468 589254..589736 1 NC_008601.1 acetyl-CoA carboxylase, biotin carboxy carrier protein subunit 589736 accB 4548468 accB Francisella tularensis subsp. novicida U112 acetyl-CoA carboxylase, biotin carboxy carrier protein subunit YP_898212.1 589254 D 401614 CDS YP_898213.1 118497163 4548469 589801..591156 1 NC_008601.1 acetyl-CoA carboxylase, biotin carboxylase subunit 591156 accC 4548469 accC Francisella tularensis subsp. novicida U112 acetyl-CoA carboxylase, biotin carboxylase subunit YP_898213.1 589801 D 401614 CDS YP_898214.1 118497164 4548470 591250..591930 1 NC_008601.1 hypothetical protein 591930 4548470 FTN_0565 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898214.1 591250 D 401614 CDS YP_898215.1 118497165 4548471 591956..593074 1 NC_008601.1 mechanosensitive ion channel protein 593074 4548471 FTN_0566 Francisella tularensis subsp. novicida U112 mechanosensitive ion channel protein YP_898215.1 591956 D 401614 CDS YP_898216.1 118497166 4548472 complement(593079..594002) 1 NC_008601.1 tRNA synthetase 594002 4548472 FTN_0567 Francisella tularensis subsp. novicida U112 tRNA synthetase YP_898216.1 593079 R 401614 CDS YP_898217.1 118497167 4548473 complement(593999..594781) 1 NC_008601.1 birA-like protein 594781 4548473 FTN_0568 Francisella tularensis subsp. novicida U112 birA-like protein YP_898217.1 593999 R 401614 CDS YP_898218.1 118497168 4548474 complement(594778..596520) 1 NC_008601.1 single-stranded-DNA-specific exonuclease 596520 recJ 4548474 recJ Francisella tularensis subsp. novicida U112 single-stranded-DNA-specific exonuclease YP_898218.1 594778 R 401614 CDS YP_898219.1 118497169 4548475 complement(596514..597620) 1 NC_008601.1 PerM family protein 597620 perM 4548475 perM Francisella tularensis subsp. novicida U112 PerM family protein YP_898219.1 596514 R 401614 CDS YP_898220.1 118497170 4548476 complement(597722..599131) 1 NC_008601.1 amino acid-polyamine-organocation (APC) superfamily protein 599131 4548476 FTN_0571 Francisella tularensis subsp. novicida U112 amino acid-polyamine-organocation (APC) superfamily protein YP_898220.1 597722 R 401614 CDS YP_898221.1 118497171 4548477 599215..600396 1 NC_008601.1 putrescine ABC transporter periplasmic protein 600396 potF 4548477 potF Francisella tularensis subsp. novicida U112 putrescine ABC transporter periplasmic protein YP_898221.1 599215 D 401614 CDS YP_898222.1 118497172 4547263 complement(600637..601452) 1 NC_008601.1 hypothetical protein 601452 4547263 FTN_0573 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898222.1 600637 R 401614 CDS YP_898223.1 118497173 4547264 complement(601671..602558) 1 NC_008601.1 GTPase 602558 4547264 FTN_0574 Francisella tularensis subsp. novicida U112 GTPase YP_898223.1 601671 R 401614 CDS YP_898224.1 118497174 4547265 602712..603431 1 NC_008601.1 hypothetical protein 603431 4547265 FTN_0575 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898224.1 602712 D 401614 CDS YP_898225.1 118497175 4547266 603499..604161 1 NC_008601.1 hypothetical protein 604161 4547266 FTN_0576 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898225.1 603499 D 401614 CDS YP_898226.1 118497176 4547267 604169..605971 1 NC_008601.1 DNA mismatch repair protein 605971 mutL 4547267 mutL Francisella tularensis subsp. novicida U112 DNA mismatch repair protein YP_898226.1 604169 D 401614 CDS YP_898227.1 118497177 4547268 606155..607378 1 NC_008601.1 major facilitator transporter 607378 4547268 FTN_0578 Francisella tularensis subsp. novicida U112 major facilitator transporter YP_898227.1 606155 D 401614 CDS YP_898228.1 118497178 4547269 complement(607385..608659) 1 NC_008601.1 major facilitator transporter 608659 4547269 FTN_0579 Francisella tularensis subsp. novicida U112 major facilitator transporter YP_898228.1 607385 R 401614 CDS YP_898229.1 118497179 4547270 complement(608767..609717) 1 NC_008601.1 thioredoxin reductase 609717 trxB 4547270 trxB Francisella tularensis subsp. novicida U112 thioredoxin reductase YP_898229.1 608767 R 401614 CDS YP_898230.1 118497180 4547271 complement(609808..611025) 1 NC_008601.1 phospholipase D 611025 4547271 FTN_0581 Francisella tularensis subsp. novicida U112 phospholipase D YP_898230.1 609808 R 401614 CDS YP_898231.1 118497181 4547272 complement(611068..611742) 1 NC_008601.1 phosphoglycolate phosphatase 611742 gph 4547272 gph Francisella tularensis subsp. novicida U112 phosphoglycolate phosphatase YP_898231.1 611068 R 401614 CDS YP_898232.1 118497182 4547273 complement(611783..612709) 1 NC_008601.1 LysR family transcriptional regulator 612709 4547273 FTN_0583 Francisella tularensis subsp. novicida U112 LysR family transcriptional regulator YP_898232.1 611783 R 401614 CDS YP_898233.1 118497183 4547274 612820..613986 1 NC_008601.1 inner membrane protein 613986 araJ 4547274 araJ Francisella tularensis subsp. novicida U112 inner membrane protein YP_898233.1 612820 D 401614 CDS YP_898234.1 118497184 4547275 complement(614001..614723) 1 NC_008601.1 copper homeostasis protein CutC family protein 614723 cutC 4547275 cutC Francisella tularensis subsp. novicida U112 copper homeostasis protein CutC family protein YP_898234.1 614001 R 401614 CDS YP_898235.1 118497185 4547276 615044..615562 1 NC_008601.1 hypothetical protein 615562 4547276 FTN_0586 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898235.1 615044 D 401614 CDS YP_898236.1 118497186 4547277 615588..616817 1 NC_008601.1 deoxyguanosinetriphosphate triphosphohydrolase 616817 4547277 FTN_0587 Francisella tularensis subsp. novicida U112 deoxyguanosinetriphosphate triphosphohydrolase YP_898236.1 615588 D 401614 CDS YP_898237.1 118497187 4547278 complement(616820..617740) 1 NC_008601.1 asparaginase 617740 4547278 FTN_0588 Francisella tularensis subsp. novicida U112 asparaginase YP_898237.1 616820 R 401614 CDS YP_898238.1 118497188 4547279 complement(617744..619189) 1 NC_008601.1 proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter 619189 4547279 FTN_0589 Francisella tularensis subsp. novicida U112 proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter YP_898238.1 617744 R 401614 CDS YP_898239.1 118497189 4547280 620283..621503 1 NC_008601.1 hypothetical protein 621503 4547280 FTN_0590 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898239.1 620283 D 401614 CDS YP_898240.1 118497190 4548950 complement(621627..622667) 1 NC_008601.1 hypothetical protein 622667 4548950 FTN_0591 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898240.1 621627 R 401614 CDS YP_898241.1 118497191 4548951 complement(623051..623476) 1 NC_008601.1 hypothetical protein 623476 4548951 FTN_0592 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898241.1 623051 R 401614 CDS YP_898242.1 118497192 4548952 complement(623588..624460) 1 NC_008601.1 succinyl-CoA synthetase, alpha subunit 624460 sucD 4548952 sucD Francisella tularensis subsp. novicida U112 succinyl-CoA synthetase, alpha subunit YP_898242.1 623588 R 401614 CDS YP_898243.1 118497193 4548953 complement(624492..625655) 1 NC_008601.1 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 625655 sucC 4548953 sucC Francisella tularensis subsp. novicida U112 succinyl-CoA synthetase subunit beta YP_898243.1 624492 R 401614 CDS YP_898244.1 118497194 4548954 625825..627741 1 NC_008601.1 hypothetical protein 627741 4548954 FTN_0595 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898244.1 625825 D 401614 CDS YP_898245.1 118497195 4548955 complement(627749..628633) 1 NC_008601.1 hypothetical protein 628633 4548955 FTN_0596 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898245.1 627749 R 401614 CDS YP_898246.1 118497196 4548956 628731..629498 1 NC_008601.1 protein-disulfide isomerase 629498 4548956 FTN_0597 Francisella tularensis subsp. novicida U112 protein-disulfide isomerase YP_898246.1 628731 D 401614 CDS YP_898247.1 118497197 4548957 complement(629505..630488) 1 NC_008601.1 tRNA-dihydrouridine synthase A 630488 4548957 FTN_0598 Francisella tularensis subsp. novicida U112 tRNA-dihydrouridine synthase A YP_898247.1 629505 R 401614 CDS YP_898248.1 118497198 4548958 complement(630522..631322) 1 NC_008601.1 hypothetical protein 631322 4548958 FTN_0599 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898248.1 630522 R 401614 CDS YP_898249.1 118497199 4548959 631504..633915 1 NC_008601.1 DNA gyrase subunit B 633915 gyrB 4548959 gyrB Francisella tularensis subsp. novicida U112 DNA gyrase subunit B YP_898249.1 631504 D 401614 CDS YP_898250.1 118497200 4548960 634045..634908 1 NC_008601.1 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS 634908 4548960 FTN_0601 Francisella tularensis subsp. novicida U112 pyridoxal biosynthesis lyase PdxS YP_898250.1 634045 D 401614 CDS YP_898251.1 118497201 4548961 634911..635450 1 NC_008601.1 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT 635450 4548961 FTN_0602 Francisella tularensis subsp. novicida U112 glutamine amidotransferase subunit PdxT YP_898251.1 634911 D 401614 CDS YP_898252.1 118497202 4548962 complement(635459..636283) 1 NC_008601.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 636283 mutM 4548962 mutM Francisella tularensis subsp. novicida U112 formamidopyrimidine-DNA glycosylase YP_898252.1 635459 R 401614 CDS YP_898253.1 118497203 4548963 636377..638476 1 NC_008601.1 AMP-binding protein 638476 4548963 FTN_0604 Francisella tularensis subsp. novicida U112 AMP-binding protein YP_898253.1 636377 D 401614 CDS YP_898254.1 118497204 4548964 638482..639399 1 NC_008601.1 S-adenosyl-methyltransferase MraW 639399 mraW 4548964 mraW Francisella tularensis subsp. novicida U112 S-adenosyl-methyltransferase MraW YP_898254.1 638482 D 401614 CDS YP_898255.1 118497205 4548965 639396..639746 1 NC_008601.1 hypothetical protein 639746 4548965 FTN_0606 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898255.1 639396 D 401614 CDS YP_898256.1 118497206 4548966 639739..641433 1 NC_008601.1 cell division protein, peptidoglycan synthetase (PBP) 641433 ftsI 4548966 ftsI Francisella tularensis subsp. novicida U112 cell division protein, peptidoglycan synthetase (PBP) YP_898256.1 639739 D 401614 CDS YP_898257.1 118497207 4548967 641539..641805 1 NC_008601.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 641805 rpsO 4548967 rpsO Francisella tularensis subsp. novicida U112 30S ribosomal protein S15 YP_898257.1 641539 D 401614 CDS YP_898258.1 118497208 4548968 641862..643943 1 NC_008601.1 polynucleotide phosphorylase/polyadenylase 643943 pnp 4548968 pnp Francisella tularensis subsp. novicida U112 polynucleotide phosphorylase/polyadenylase YP_898258.1 641862 D 401614 CDS YP_898259.1 118497209 4548969 643949..644299 1 NC_008601.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 644299 4548969 FTN_0610 Francisella tularensis subsp. novicida U112 iron-sulfur cluster insertion protein ErpA YP_898259.1 643949 D 401614 CDS YP_898260.1 118497210 4548188 644330..645157 1 NC_008601.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 645157 kdsA 4548188 kdsA Francisella tularensis subsp. novicida U112 2-dehydro-3-deoxyphosphooctonate aldolase YP_898260.1 644330 D 401614 CDS YP_898261.1 118497211 4548189 645168..645833 1 NC_008601.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 645833 udk 4548189 udk Francisella tularensis subsp. novicida U112 uridine kinase YP_898261.1 645168 D 401614 CDS YP_898262.1 118497212 4548190 645826..646044 1 NC_008601.1 DNA-directed RNA polymerase subunit K/omega 646044 rpoZ 4548190 rpoZ Francisella tularensis subsp. novicida U112 DNA-directed RNA polymerase subunit K/omega YP_898262.1 645826 D 401614 CDS YP_898263.1 118497213 4548192 646311..646883 1 NC_008601.1 hypothetical protein 646883 4548192 FTN_0615 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898263.1 646311 D 401614 CDS YP_898264.1 118497214 4548193 646972..648321 1 NC_008601.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase 648321 rumA 4548193 rumA Francisella tularensis subsp. novicida U112 23S rRNA 5-methyluridine methyltransferase YP_898264.1 646972 D 401614 CDS YP_898265.1 118497215 4548194 648331..649296 1 NC_008601.1 ROK family protein 649296 4548194 FTN_0617 Francisella tularensis subsp. novicida U112 ROK family protein YP_898265.1 648331 D 401614 CDS YP_898266.1 118497216 4548195 649296..650243 1 NC_008601.1 ROK family protein 650243 4548195 FTN_0618 Francisella tularensis subsp. novicida U112 ROK family protein YP_898266.1 649296 D 401614 CDS YP_898267.1 118497217 4548197 651130..652368 1 NC_008601.1 major facilitator transporter 652368 4548197 FTN_0620 Francisella tularensis subsp. novicida U112 major facilitator transporter YP_898267.1 651130 D 401614 CDS YP_898268.1 118497218 4548198 652477..653847 1 NC_008601.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 653847 eno 4548198 eno Francisella tularensis subsp. novicida U112 phosphopyruvate hydratase YP_898268.1 652477 D 401614 CDS YP_898269.1 118497219 4548199 653855..654145 1 NC_008601.1 cell division protein, septum formation initiator 654145 ftsB 4548199 ftsB Francisella tularensis subsp. novicida U112 cell division protein, septum formation initiator YP_898269.1 653855 D 401614 CDS YP_898270.1 118497220 4548200 654135..654824 1 NC_008601.1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 654824 ispD 4548200 ispD Francisella tularensis subsp. novicida U112 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_898270.1 654135 D 401614 CDS YP_898271.1 118497221 4548201 complement(654829..656091) 1 NC_008601.1 serine permease 656091 4548201 FTN_0624 Francisella tularensis subsp. novicida U112 serine permease YP_898271.1 654829 R 401614 CDS YP_898272.1 118497222 4548202 complement(656093..657148) 1 NC_008601.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase 657148 tdh 4548202 tdh Francisella tularensis subsp. novicida U112 L-threonine 3-dehydrogenase YP_898272.1 656093 R 401614 CDS YP_898273.1 118497223 4548203 complement(657171..658367) 1 NC_008601.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate coenzyme A ligase 658367 kbl 4548203 kbl Francisella tularensis subsp. novicida U112 2-amino-3-ketobutyrate coenzyme A ligase YP_898273.1 657171 R 401614 CDS YP_898274.1 118497224 4548204 658901..661513 1 NC_008601.1 glycosyl hydrolase family chitinase 661513 chiA 4548204 chiA Francisella tularensis subsp. novicida U112 glycosyl hydrolase family chitinase YP_898274.1 658901 D 401614 CDS YP_898275.1 118497225 4548205 661707..662336 1 NC_008601.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 662336 upp 4548205 upp Francisella tularensis subsp. novicida U112 uracil phosphoribosyltransferase YP_898275.1 661707 D 401614 CDS YP_898276.1 118497226 4547943 662421..663254 1 NC_008601.1 formyltetrahydrofolate deformylase 663254 purU 4547943 purU Francisella tularensis subsp. novicida U112 formyltetrahydrofolate deformylase YP_898276.1 662421 D 401614 CDS YP_898277.1 118497227 4547944 663345..663689 1 NC_008601.1 hypothetical protein 663689 4547944 FTN_0630 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898277.1 663345 D 401614 CDS YP_898278.1 118497228 4547945 663750..664970 1 NC_008601.1 metabolite:H+ symporter (MHS) family protein 664970 4547945 FTN_0631 Francisella tularensis subsp. novicida U112 metabolite:H+ symporter (MHS) family protein YP_898278.1 663750 D 401614 CDS YP_898279.1 118497229 4547946 complement(664954..666279) 1 NC_008601.1 dGTP triphosphohydrolase 666279 4547946 FTN_0632 Francisella tularensis subsp. novicida U112 dGTP triphosphohydrolase YP_898279.1 664954 R 401614 CDS YP_898280.1 118497230 4547947 complement(666383..668602) 1 NC_008601.1 peroxidase/catalase 668602 katG 4547947 katG Francisella tularensis subsp. novicida U112 peroxidase/catalase YP_898280.1 666383 R 401614 CDS YP_898281.1 118497231 4547948 complement(668807..669595) 1 NC_008601.1 short chain dehydrogenase/reductase family oxidoreductase 669595 4547948 FTN_0634 Francisella tularensis subsp. novicida U112 short chain dehydrogenase/reductase family oxidoreductase YP_898281.1 668807 R 401614 CDS YP_898282.1 118497232 4547949 complement(669589..670983) 1 NC_008601.1 serine-type D-Ala-D-Ala carboxypeptidase 670983 4547949 FTN_0635 Francisella tularensis subsp. novicida U112 serine-type D-Ala-D-Ala carboxypeptidase YP_898282.1 669589 R 401614 CDS YP_898283.1 118497233 4547950 complement(670999..672315) 1 NC_008601.1 glycerol-3-phosphate transporter 672315 glpT 4547950 glpT Francisella tularensis subsp. novicida U112 glycerol-3-phosphate transporter YP_898283.1 670999 R 401614 CDS YP_898284.1 118497234 4547951 complement(673286..674314) 1 NC_008601.1 glycerophosphoryl diester phosphodiesterase 674314 ugpQ 4547951 ugpQ Francisella tularensis subsp. novicida U112 glycerophosphoryl diester phosphodiesterase YP_898284.1 673286 R 401614 CDS YP_898285.1 118497235 4547952 674546..676090 1 NC_008601.1 sulfate permease family protein 676090 4547952 FTN_0638 Francisella tularensis subsp. novicida U112 sulfate permease family protein YP_898285.1 674546 D 401614 CDS YP_898286.1 118497236 4547953 676090..676470 1 NC_008601.1 endoribonuclease L-PSP 676470 4547953 FTN_0639 Francisella tularensis subsp. novicida U112 endoribonuclease L-PSP YP_898286.1 676090 D 401614 CDS YP_898287.1 118497237 4547954 676608..677858 1 NC_008601.1 C4-dicarboxylate transport protein 677858 dctA 4547954 dctA Francisella tularensis subsp. novicida U112 C4-dicarboxylate transport protein YP_898287.1 676608 D 401614 CDS YP_898288.1 118497238 4547955 complement(677860..679509) 1 NC_008601.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 679509 cydC 4547955 cydC Francisella tularensis subsp. novicida U112 cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_898288.1 677860 R 401614 CDS YP_898289.1 118497239 4547956 complement(679506..681287) 1 NC_008601.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein 681287 cydD 4547956 cydD Francisella tularensis subsp. novicida U112 cysteine/glutathione ABC transporter membrane/ATP-binding protein YP_898289.1 679506 R 401614 CDS YP_898290.1 118497240 4547957 681664..682173 1 NC_008601.1 hypothetical protein 682173 4547957 FTN_0643 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898290.1 681664 D 401614 CDS YP_898291.1 118497241 4547958 682201..682401 1 NC_008601.1 hypothetical protein 682401 4547958 FTN_0644 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898291.1 682201 D 401614 CDS YP_898292.1 118497242 4547959 complement(682405..683664) 1 NC_008601.1 multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) transporter 683664 4547959 FTN_0645 Francisella tularensis subsp. novicida U112 multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) transporter YP_898292.1 682405 R 401614 CDS YP_898293.1 118497243 4547960 complement(683742..684641) 1 NC_008601.1 ROK family protein 684641 cscK 4547960 cscK Francisella tularensis subsp. novicida U112 ROK family protein YP_898293.1 683742 R 401614 CDS YP_898294.1 118497244 4547961 complement(684751..686031) 1 NC_008601.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 686031 serS 4547961 serS Francisella tularensis subsp. novicida U112 seryl-tRNA synthetase YP_898294.1 684751 R 401614 CDS YP_898295.1 118497245 4547871 complement(686046..687584) 1 NC_008601.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 687584 gpmI 4547871 gpmI Francisella tularensis subsp. novicida U112 phosphoglyceromutase YP_898295.1 686046 R 401614 CDS YP_898296.1 118497246 4547872 687803..690835 1 NC_008601.1 4Fe-4S ferredoxin 690835 4547872 FTN_0649 Francisella tularensis subsp. novicida U112 4Fe-4S ferredoxin YP_898296.1 687803 D 401614 CDS YP_898297.1 118497247 4547874 complement(691032..691433) 1 NC_008601.1 cytidine deaminase 691433 cdd 4547874 cdd Francisella tularensis subsp. novicida U112 cytidine deaminase YP_898297.1 691032 R 401614 CDS YP_898298.1 118497248 4547875 complement(691454..692257) 1 NC_008601.1 uridine phosphorylase 692257 udp 4547875 udp Francisella tularensis subsp. novicida U112 uridine phosphorylase YP_898298.1 691454 R 401614 CDS YP_898299.1 118497249 4547876 692373..692984 1 NC_008601.1 tRNA-(ms(2)io(6)a)-hydroxylase 692984 miaE 4547876 miaE Francisella tularensis subsp. novicida U112 tRNA-(ms(2)io(6)a)-hydroxylase YP_898299.1 692373 D 401614 CDS YP_898300.1 118497250 4547877 complement(693036..693686) 1 NC_008601.1 hypothetical protein 693686 4547877 FTN_0654 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898300.1 693036 R 401614 CDS YP_898301.1 118497251 4547878 complement(693720..694298) 1 NC_008601.1 N6-adenine-specific methylase 694298 4547878 FTN_0655 Francisella tularensis subsp. novicida U112 N6-adenine-specific methylase YP_898301.1 693720 R 401614 CDS YP_898302.1 118497252 4547879 complement(694299..695522) 1 NC_008601.1 zinc-dependent peptidase 695522 4547879 FTN_0656 Francisella tularensis subsp. novicida U112 zinc-dependent peptidase YP_898302.1 694299 R 401614 CDS YP_898303.1 118497253 4547880 complement(695529..696782) 1 NC_008601.1 M16 family metallopeptidase 696782 4547880 FTN_0657 Francisella tularensis subsp. novicida U112 M16 family metallopeptidase YP_898303.1 695529 R 401614 CDS YP_898304.1 118497254 4547881 complement(696790..697851) 1 NC_008601.1 membrane protein 697851 4547881 FTN_0658 Francisella tularensis subsp. novicida U112 membrane protein YP_898304.1 696790 R 401614 CDS YP_898305.1 118497255 4547882 complement(697851..698933) 1 NC_008601.1 membrane protein 698933 4547882 FTN_0659 Francisella tularensis subsp. novicida U112 membrane protein YP_898305.1 697851 R 401614 CDS YP_898306.1 118497256 4547883 699099..700538 1 NC_008601.1 cytosol aminopeptidase 700538 pepA 4547883 pepA Francisella tularensis subsp. novicida U112 cytosol aminopeptidase YP_898306.1 699099 D 401614 CDS YP_898307.1 118497257 4547884 700640..702100 1 NC_008601.1 IMP dehydrogenase/GMP reductase 702100 guaB 4547884 guaB Francisella tularensis subsp. novicida U112 IMP dehydrogenase/GMP reductase YP_898307.1 700640 D 401614 CDS YP_898308.1 118497258 4547885 702166..702819 1 NC_008601.1 thiamine pyrophosphokinase 702819 4547885 FTN_0662 Francisella tularensis subsp. novicida U112 thiamine pyrophosphokinase YP_898308.1 702166 D 401614 CDS YP_898309.1 118497259 4547886 702806..704428 1 NC_008601.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 704428 pgi 4547886 pgi Francisella tularensis subsp. novicida U112 glucose-6-phosphate isomerase YP_898309.1 702806 D 401614 CDS YP_898310.1 118497260 4547887 704429..705013 1 NC_008601.1 Type IV pili, pilus assembly protein 705013 fimT 4547887 fimT Francisella tularensis subsp. novicida U112 Type IV pili, pilus assembly protein YP_898310.1 704429 D 401614 CDS YP_898311.1 118497261 4547888 705047..705529 1 NC_008601.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 705529 greA 4547888 greA Francisella tularensis subsp. novicida U112 transcription elongation factor GreA YP_898311.1 705047 D 401614 CDS YP_898312.1 118497262 4548057 705568..708390 1 NC_008601.1 excinuclease ABC subunit A 708390 uvrA 4548057 uvrA Francisella tularensis subsp. novicida U112 excinuclease ABC subunit A YP_898312.1 705568 D 401614 CDS YP_898313.1 118497263 4548058 complement(708396..709784) 1 NC_008601.1 drug:H+ antiporter-1 (DHA2) family protein 709784 4548058 FTN_0667 Francisella tularensis subsp. novicida U112 drug:H+ antiporter-1 (DHA2) family protein YP_898313.1 708396 R 401614 CDS YP_898314.1 118497264 4548059 709997..711943 1 NC_008601.1 ATP-dependent metalloprotease 711943 hflB 4548059 hflB Francisella tularensis subsp. novicida U112 ATP-dependent metalloprotease YP_898314.1 709997 D 401614 CDS YP_898315.1 118497265 4548060 712184..712906 1 NC_008601.1 purine nucleoside phosphorylase 712906 deoD 4548060 deoD Francisella tularensis subsp. novicida U112 purine nucleoside phosphorylase YP_898315.1 712184 D 401614 CDS YP_898316.1 118497266 4548061 complement(712903..713352) 1 NC_008601.1 hypothetical protein 713352 4548061 FTN_0670 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898316.1 712903 R 401614 CDS YP_898317.1 118497267 4548062 complement(713356..714384) 1 NC_008601.1 hypothetical protein 714384 4548062 FTN_0671 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898317.1 713356 R 401614 CDS YP_898318.1 118497268 4548063 714516..717236 1 NC_008601.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 717236 secA 4548063 secA Francisella tularensis subsp. novicida U112 preprotein translocase subunit SecA YP_898318.1 714516 D 401614 CDS YP_898319.1 118497269 4548064 717345..717911 1 NC_008601.1 3-methyladenine DNA glycosylase 717911 tag 4548064 tag Francisella tularensis subsp. novicida U112 3-methyladenine DNA glycosylase YP_898319.1 717345 D 401614 CDS YP_898320.1 118497270 4548065 complement(717903..719030) 1 NC_008601.1 glycerate kinase 719030 glxK 4548065 glxK Francisella tularensis subsp. novicida U112 glycerate kinase YP_898320.1 717903 R 401614 CDS YP_898321.1 118497271 4548066 719301..719615 1 NC_008601.1 50S ribosomal protein L21 719615 rplU 4548066 rplU Francisella tularensis subsp. novicida U112 50S ribosomal protein L21 YP_898321.1 719301 D 401614 CDS YP_898322.1 118497272 4548067 719646..719900 1 NC_008601.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 719900 rpmA 4548067 rpmA Francisella tularensis subsp. novicida U112 50S ribosomal protein L27 YP_898322.1 719646 D 401614 CDS YP_898323.1 118497273 4548068 721006..721383 1 NC_008601.1 hypothetical protein 721383 4548068 FTN_0677 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898323.1 721006 D 401614 CDS YP_898324.1 118497274 4548069 complement(721380..722594) 1 NC_008601.1 drug:H+ antiporter-1 (DHA1) family protein 722594 4548069 FTN_0678 Francisella tularensis subsp. novicida U112 drug:H+ antiporter-1 (DHA1) family protein YP_898324.1 721380 R 401614 CDS YP_898325.1 118497275 4548070 complement(722623..723717) 1 NC_008601.1 ribonuclease D 723717 rnd 4548070 rnd Francisella tularensis subsp. novicida U112 ribonuclease D YP_898325.1 722623 R 401614 CDS YP_898326.1 118497276 4548071 723838..725676 1 NC_008601.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 725676 uvrC 4548071 uvrC Francisella tularensis subsp. novicida U112 excinuclease ABC subunit C YP_898326.1 723838 D 401614 CDS YP_898327.1 118497277 4548072 725743..726369 1 NC_008601.1 hypothetical protein 726369 4548072 FTN_0681 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898327.1 725743 D 401614 CDS YP_898328.1 118497278 4548073 726759..726947 1 NC_008601.1 hypothetical protein 726947 4548073 FTN_0682 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898328.1 726759 D 401614 CDS YP_898329.1 118497279 4548074 726940..727692 1 NC_008601.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 727692 kdsB 4548074 kdsB Francisella tularensis subsp. novicida U112 3-deoxy-manno-octulosonate cytidylyltransferase YP_898329.1 726940 D 401614 CDS YP_898330.1 118497280 4548075 727685..728080 1 NC_008601.1 hypothetical protein 728080 4548075 FTN_0684 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898330.1 727685 D 401614 CDS YP_898331.1 118497281 4547301 complement(728077..729225) 1 NC_008601.1 galactokinase 729225 galK 4547301 galK Francisella tularensis subsp. novicida U112 galactokinase YP_898331.1 728077 R 401614 CDS YP_898332.1 118497282 4547302 complement(729228..730253) 1 NC_008601.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase 730253 galT 4547302 galT Francisella tularensis subsp. novicida U112 galactose-1-phosphate uridylyltransferase YP_898332.1 729228 R 401614 CDS YP_898333.1 118497283 4547303 730344..731726 1 NC_008601.1 major facilitator superfamily galactose-proton symporter 731726 galP1 4547303 galP1 Francisella tularensis subsp. novicida U112 major facilitator superfamily galactose-proton symporter YP_898333.1 730344 D 401614 CDS YP_898334.1 118497284 4547304 731758..733152 1 NC_008601.1 major facilitator superfamily galactose-proton symporter 733152 galP2 4547304 galP2 Francisella tularensis subsp. novicida U112 major facilitator superfamily galactose-proton symporter YP_898334.1 731758 D 401614 CDS YP_898335.1 118497285 4547305 733247..733525 1 NC_008601.1 parvulin-like peptidyl-prolyl isomerase domain-containing protein 733525 ppiC 4547305 ppiC Francisella tularensis subsp. novicida U112 parvulin-like peptidyl-prolyl isomerase domain-containing protein YP_898335.1 733247 D 401614 CDS YP_898336.1 118497286 4547306 733590..735299 1 NC_008601.1 DEAD/DEAH box helicase 735299 deaD 4547306 deaD Francisella tularensis subsp. novicida U112 DEAD/DEAH box helicase YP_898336.1 733590 D 401614 CDS YP_898337.1 118497287 4547307 735416..735988 1 NC_008601.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 735988 gmk 4547307 gmk Francisella tularensis subsp. novicida U112 guanylate kinase YP_898337.1 735416 D 401614 CDS YP_898338.1 118497288 4547308 736009..737034 1 NC_008601.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 737034 nadA 4547308 nadA Francisella tularensis subsp. novicida U112 quinolinate synthetase YP_898338.1 736009 D 401614 CDS YP_898339.1 118497289 4547309 737043..737906 1 NC_008601.1 nicotinate-nucleotide pyrophosphorylase 737906 nadC 4547309 nadC Francisella tularensis subsp. novicida U112 nicotinate-nucleotide pyrophosphorylase YP_898339.1 737043 D 401614 CDS YP_898340.1 118497290 4547310 737909..739396 1 NC_008601.1 L-aspartate oxidase 739396 nadB 4547310 nadB Francisella tularensis subsp. novicida U112 L-aspartate oxidase YP_898340.1 737909 D 401614 CDS YP_898341.1 118497291 4547311 739415..740455 1 NC_008601.1 deoxyadenosine deaminase/adenosine deaminase 740455 add 4547311 add Francisella tularensis subsp. novicida U112 deoxyadenosine deaminase/adenosine deaminase YP_898341.1 739415 D 401614 CDS YP_898342.1 118497292 4547312 complement(740450..741076) 1 NC_008601.1 hypothetical protein 741076 4547312 FTN_0696 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898342.1 740450 R 401614 CDS YP_898343.1 118497293 4547313 741230..741520 1 NC_008601.1 hypothetical protein 741520 4547313 FTN_0697 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898343.1 741230 D 401614 CDS YP_898344.1 118497294 4547314 741553..742023 1 NC_008601.1 glutathione peroxidase 742023 4547314 FTN_0698 Francisella tularensis subsp. novicida U112 glutathione peroxidase YP_898344.1 741553 D 401614 CDS YP_898345.1 118497295 4547315 742065..743231 1 NC_008601.1 hypothetical protein 743231 4547315 FTN_0699 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898345.1 742065 D 401614 CDS YP_898346.1 118497296 4547316 743228..744298 1 NC_008601.1 hypothetical protein 744298 4547316 FTN_0700 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898346.1 743228 D 401614 CDS YP_898347.1 118497297 4547317 744311..744958 1 NC_008601.1 hypothetical protein 744958 4547317 FTN_0701 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898347.1 744311 D 401614 CDS YP_898348.1 118497298 4547318 745266..746768 1 NC_008601.1 hypothetical protein 746768 4547318 FTN_0702 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898348.1 745266 D 401614 CDS YP_898349.1 118497299 4547319 746848..747420 1 NC_008601.1 type I restriction-modification system subunit S 747420 4547319 FTN_0703 Francisella tularensis subsp. novicida U112 type I restriction-modification system subunit S YP_898349.1 746848 D 401614 CDS YP_898350.1 118497300 4548780 747676..749163 1 NC_008601.1 type I restriction-modification system subunit M (methyltransferase) 749163 4548780 FTN_0704 Francisella tularensis subsp. novicida U112 type I restriction-modification system subunit M (methyltransferase) YP_898350.1 747676 D 401614 CDS YP_898351.1 118497301 4548781 749168..750079 1 NC_008601.1 abortive infection bacteriophage resistance protein 750079 4548781 FTN_0705 Francisella tularensis subsp. novicida U112 abortive infection bacteriophage resistance protein YP_898351.1 749168 D 401614 CDS YP_898352.1 118497302 4548782 750173..750676 1 NC_008601.1 hypothetical protein 750676 4548782 FTN_0706 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898352.1 750173 D 401614 CDS YP_898353.1 118497303 4548783 750859..752079 1 NC_008601.1 type I restriction-modification system subunit S 752079 4548783 FTN_0707 Francisella tularensis subsp. novicida U112 type I restriction-modification system subunit S YP_898353.1 750859 D 401614 CDS YP_898354.1 118497304 4548784 752105..752350 1 NC_008601.1 hypothetical protein 752350 4548784 FTN_0708 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898354.1 752105 D 401614 CDS YP_898355.1 118497305 4548785 752359..753105 1 NC_008601.1 hypothetical protein 753105 4548785 FTN_0709 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898355.1 752359 D 401614 CDS YP_898356.1 118497306 4548786 753221..756331 1 NC_008601.1 type I restriction-modification system subunit R (restriction) 756331 4548786 FTN_0710 Francisella tularensis subsp. novicida U112 type I restriction-modification system subunit R (restriction) YP_898356.1 753221 D 401614 CDS YP_898357.1 118497307 4548787 756324..756983 1 NC_008601.1 metal-dependent hydrolase 756983 4548787 FTN_0711 Francisella tularensis subsp. novicida U112 metal-dependent hydrolase YP_898357.1 756324 D 401614 CDS YP_898358.1 118497308 4548788 complement(757042..757410) 1 NC_008601.1 heat shock protein 15 (HSP15) 757410 hslR 4548788 hslR Francisella tularensis subsp. novicida U112 heat shock protein 15 (HSP15) YP_898358.1 757042 R 401614 CDS YP_898359.1 118497309 4548789 complement(757650..760250) 1 NC_008601.1 organic solvent tolerance protein OstA 760250 ostA2 4548789 ostA2 Francisella tularensis subsp. novicida U112 organic solvent tolerance protein OstA YP_898359.1 757650 R 401614 CDS YP_898360.1 118497310 4548790 760571..766129 1 NC_008601.1 hypothetical protein 766129 4548790 FTN_0714 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898360.1 760571 D 401614 CDS YP_898361.1 118497311 4548791 766940..770710 1 NC_008601.1 hypothetical protein 770710 4548791 FTN_0715 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898361.1 766940 D 401614 CDS YP_898362.1 118497312 4548792 771325..772140 1 NC_008601.1 hypothetical protein 772140 4548792 FTN_0716 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898362.1 771325 D 401614 CDS YP_898363.1 118497313 4548793 complement(772240..773937) 1 NC_008601.1 hypothetical protein 773937 4548793 FTN_0717 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898363.1 772240 R 401614 CDS YP_898364.1 118497314 4548794 complement(773934..774791) 1 NC_008601.1 membrane fusion protein 774791 4548794 FTN_0718 Francisella tularensis subsp. novicida U112 membrane fusion protein YP_898364.1 773934 R 401614 CDS YP_898365.1 118497315 4548795 complement(774793..774996) 1 NC_008601.1 hypothetical protein 774996 4548795 FTN_0719 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898365.1 774793 R 401614 CDS YP_898366.1 118497316 4548796 775195..775911 1 NC_008601.1 IclR family transcriptional regulator 775911 4548796 FTN_0720 Francisella tularensis subsp. novicida U112 IclR family transcriptional regulator YP_898366.1 775195 D 401614 CDS YP_898367.1 118497317 4548797 complement(776065..777051) 1 NC_008601.1 hypothetical protein 777051 4548797 FTN_0721 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898367.1 776065 R 401614 CDS YP_898368.1 118497318 4548798 777263..778249 1 NC_008601.1 hypothetical protein 778249 4548798 FTN_0722 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898368.1 777263 D 401614 CDS YP_898369.1 118497319 4548799 complement(778319..778522) 1 NC_008601.1 cold shock protein 778522 cspA 4548799 cspA Francisella tularensis subsp. novicida U112 cold shock protein YP_898369.1 778319 R 401614 CDS YP_898370.1 118497320 4547853 complement(778721..779050) 1 NC_008601.1 hypothetical protein 779050 4547853 FTN_0724 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898370.1 778721 R 401614 CDS YP_898371.1 118497321 4547854 779296..779496 1 NC_008601.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 779496 rpsU 4547854 rpsU Francisella tularensis subsp. novicida U112 30S ribosomal protein S21 YP_898371.1 779296 D 401614 CDS YP_898372.1 118497322 4547856 780006..780575 1 NC_008601.1 hypothetical protein 780575 4547856 FTN_0727 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898372.1 780006 D 401614 CDS YP_898373.1 118497323 4547857 780666..781805 1 NC_008601.1 Co/Zn/Cd cation transporter 781805 4547857 FTN_0728 Francisella tularensis subsp. novicida U112 Co/Zn/Cd cation transporter YP_898373.1 780666 D 401614 CDS YP_898374.1 118497324 4547858 781822..782685 1 NC_008601.1 UTP--glucose-1-phosphate uridylyltransferase 782685 galU 4547858 galU Francisella tularensis subsp. novicida U112 UTP--glucose-1-phosphate uridylyltransferase YP_898374.1 781822 D 401614 CDS YP_898375.1 118497325 4547859 782807..784744 1 NC_008601.1 acyl-coenzyme A synthetase/AMP-(fatty) acid ligase 784744 acs 4547859 acs Francisella tularensis subsp. novicida U112 acyl-coenzyme A synthetase/AMP-(fatty) acid ligase YP_898375.1 782807 D 401614 CDS YP_898376.1 118497326 4547860 784756..785673 1 NC_008601.1 hypothetical protein 785673 4547860 FTN_0731 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898376.1 784756 D 401614 CDS YP_898377.1 118497327 4547861 complement(785676..785882) 1 NC_008601.1 hypothetical protein 785882 4547861 FTN_0732 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898377.1 785676 R 401614 CDS YP_898378.1 118497328 4547862 complement(785967..786260) 1 NC_008601.1 hypothetical protein 786260 4547862 FTN_0733 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898378.1 785967 R 401614 CDS YP_898379.1 118497329 4547863 complement(786282..787331) 1 NC_008601.1 RecFOR complex, RecF component 787331 recF 4547863 recF Francisella tularensis subsp. novicida U112 RecFOR complex, RecF component YP_898379.1 786282 R 401614 CDS YP_898380.1 118497330 4547864 complement(787335..788081) 1 NC_008601.1 Mg-dependent DNase 788081 4547864 FTN_0735 Francisella tularensis subsp. novicida U112 Mg-dependent DNase YP_898380.1 787335 R 401614 CDS YP_898381.1 118497331 4547865 788274..790358 1 NC_008601.1 glycyl-tRNA synthetase subunit beta 790358 glyS 4547865 glyS Francisella tularensis subsp. novicida U112 glycyl-tRNA synthetase subunit beta YP_898381.1 788274 D 401614 CDS YP_898382.1 118497332 4547866 complement(790570..791376) 1 NC_008601.1 putrescine ABC transporter membrane protein subunit I 791376 potI 4547866 potI Francisella tularensis subsp. novicida U112 putrescine ABC transporter membrane protein subunit I YP_898382.1 790570 R 401614 CDS YP_898383.1 118497333 4547867 complement(791390..792307) 1 NC_008601.1 putrescine ABC transporter membrane protein subunit H 792307 potH 4547867 potH Francisella tularensis subsp. novicida U112 putrescine ABC transporter membrane protein subunit H YP_898383.1 791390 R 401614 CDS YP_898384.1 118497334 4547868 complement(792271..793392) 1 NC_008601.1 putrescine ABC transporter ATP-binding protein 793392 potG 4547868 potG Francisella tularensis subsp. novicida U112 putrescine ABC transporter ATP-binding protein YP_898384.1 792271 R 401614 CDS YP_898385.1 118497335 4547869 793798..794058 1 NC_008601.1 hypothetical protein 794058 4547869 FTN_0740 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898385.1 793798 D 401614 CDS YP_898386.1 118497336 4547870 complement(794171..795628) 1 NC_008601.1 proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter 795628 4547870 FTN_0741 Francisella tularensis subsp. novicida U112 proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter YP_898386.1 794171 R 401614 CDS YP_898387.1 118497337 4548236 796240..796890 1 NC_008601.1 phosphoserine phosphatase 796890 serB 4548236 serB Francisella tularensis subsp. novicida U112 phosphoserine phosphatase YP_898387.1 796240 D 401614 CDS YP_898388.1 118497338 4548237 complement(796879..797901) 1 NC_008601.1 hypothetical protein 797901 4548237 FTN_0743 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898388.1 796879 R 401614 CDS YP_898389.1 118497339 4548238 797981..798379 1 NC_008601.1 hypothetical protein 798379 4548238 FTN_0744 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898389.1 797981 D 401614 CDS YP_898390.1 118497340 4548239 798391..799098 1 NC_008601.1 hypothetical protein 799098 4548239 FTN_0745 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898390.1 798391 D 401614 CDS YP_898391.1 118497341 4548240 799235..800332 1 NC_008601.1 alanine racemase 800332 alr 4548240 alr Francisella tularensis subsp. novicida U112 alanine racemase YP_898391.1 799235 D 401614 CDS YP_898392.1 118497342 4548241 800413..802023 1 NC_008601.1 amino acid-polyamine-organocation (APC) superfamily protein 802023 4548241 FTN_0747 Francisella tularensis subsp. novicida U112 amino acid-polyamine-organocation (APC) superfamily protein YP_898392.1 800413 D 401614 CDS YP_898393.1 118497343 4548242 802109..802951 1 NC_008601.1 prephenate dehydratase 802951 pheA 4548242 pheA Francisella tularensis subsp. novicida U112 prephenate dehydratase YP_898393.1 802109 D 401614 CDS YP_898394.1 118497344 4548243 802977..803645 1 NC_008601.1 hypothetical protein 803645 4548243 FTN_0749 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898394.1 802977 D 401614 CDS YP_898395.1 118497345 4548244 803701..805074 1 NC_008601.1 L-serine dehydratase 805074 sdaA 4548244 sdaA Francisella tularensis subsp. novicida U112 L-serine dehydratase YP_898395.1 803701 D 401614 CDS YP_898396.1 118497346 4548245 805177..806400 1 NC_008601.1 selenocysteine lyase 806400 sufS 4548245 sufS Francisella tularensis subsp. novicida U112 selenocysteine lyase YP_898396.1 805177 D 401614 CDS YP_898397.1 118497347 4548246 806421..806777 1 NC_008601.1 hypothetical protein 806777 4548246 FTN_0752 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898397.1 806421 D 401614 CDS YP_898398.1 118497348 4548247 806791..807342 1 NC_008601.1 hypothetical protein 807342 4548247 FTN_0753 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898398.1 806791 D 401614 CDS YP_898399.1 118497349 4548248 807354..807842 1 NC_008601.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 807842 coaD 4548248 coaD Francisella tularensis subsp. novicida U112 phosphopantetheine adenylyltransferase YP_898399.1 807354 D 401614 CDS YP_898400.1 118497350 4548249 807847..808092 1 NC_008601.1 4Fe-4S ferredoxin 808092 4548249 FTN_0755 Francisella tularensis subsp. novicida U112 4Fe-4S ferredoxin YP_898400.1 807847 D 401614 CDS YP_898401.1 118497351 4548250 808202..809380 1 NC_008601.1 OmpA family protein 809380 fopA 4548250 fopA Francisella tularensis subsp. novicida U112 OmpA family protein YP_898401.1 808202 D 401614 CDS YP_898402.1 118497352 4548251 810052..814941 1 NC_008601.1 membrane protein 814941 4548251 FTN_0757 Francisella tularensis subsp. novicida U112 membrane protein YP_898402.1 810052 D 401614 CDS YP_898403.1 118497353 4548252 814922..815878 1 NC_008601.1 hypothetical protein 815878 4548252 FTN_0758 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898403.1 814922 D 401614 CDS YP_898404.1 118497354 4548253 816036..816329 1 NC_008601.1 hypothetical protein 816329 4548253 FTN_0759 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898404.1 816036 D 401614 CDS YP_898405.1 118497355 4548254 816310..816900 1 NC_008601.1 hypothetical protein 816900 4548254 FTN_0760 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898405.1 816310 D 401614 CDS YP_898406.1 118497356 4548255 818940..820025 1 NC_008601.1 radical SAM family protein 820025 4548255 FTN_0761 Francisella tularensis subsp. novicida U112 radical SAM family protein YP_898406.1 818940 D 401614 CDS YP_898407.1 118497357 4547569 820018..820266 1 NC_008601.1 glutaredoxin like protein 820266 grxC 4547569 grxC Francisella tularensis subsp. novicida U112 glutaredoxin like protein YP_898407.1 820018 D 401614 CDS YP_898408.1 118497358 4547570 820263..820712 1 NC_008601.1 thioesterase superfamily protein 820712 4547570 FTN_0763 Francisella tularensis subsp. novicida U112 thioesterase superfamily protein YP_898408.1 820263 D 401614 CDS YP_898409.1 118497359 4547571 complement(820725..821078) 1 NC_008601.1 hypothetical protein 821078 4547571 FTN_0764 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898409.1 820725 R 401614 CDS YP_898410.1 118497360 4547572 complement(821243..822211) 1 NC_008601.1 choloylglycine hydrolase family protein 822211 4547572 FTN_0765 Francisella tularensis subsp. novicida U112 choloylglycine hydrolase family protein YP_898410.1 821243 R 401614 CDS YP_898411.1 118497361 4547573 complement(822306..823058) 1 NC_008601.1 rRNA methyltransferase 823058 spoU 4547573 spoU Francisella tularensis subsp. novicida U112 rRNA methyltransferase YP_898411.1 822306 R 401614 CDS YP_898412.1 118497362 4547574 823200..825152 1 NC_008601.1 betaine/carnitine/choline transporter (BCCT) family protein 825152 betT 4547574 betT Francisella tularensis subsp. novicida U112 betaine/carnitine/choline transporter (BCCT) family protein YP_898412.1 823200 D 401614 CDS YP_898413.1 118497363 4547575 complement(825145..825621) 1 NC_008601.1 tryptophan-rich sensory protein 825621 tspO 4547575 tspO Francisella tularensis subsp. novicida U112 tryptophan-rich sensory protein YP_898413.1 825145 R 401614 CDS YP_898414.1 118497364 4547576 825750..826604 1 NC_008601.1 this fusion consists of methionine sulfoxide B reductase at the N-terminus and A at the C-terminus; A and B are stereospecific enzymes that recognize the damaged produces of oxidative stress, S and R epimers of methionine sulfoxide, respectively; a fusion protein of these enzymes with thioredoxin provides protection against oxidative stress in Neisseria gonorrhoeae; bifunctional methionine sulfoxide reductase B/A protein 826604 4547576 FTN_0769 Francisella tularensis subsp. novicida U112 bifunctional methionine sulfoxide reductase B/A protein YP_898414.1 825750 D 401614 CDS YP_898415.1 118497365 4547577 complement(826601..827803) 1 NC_008601.1 drug:H+ antiporter-1 (DHA1) family protein 827803 4547577 FTN_0770 Francisella tularensis subsp. novicida U112 drug:H+ antiporter-1 (DHA1) family protein YP_898415.1 826601 R 401614 CDS YP_898416.1 118497366 4547578 complement(828083..829204) 1 NC_008601.1 protein-disulfide isomerase 829204 4547578 FTN_0771 Francisella tularensis subsp. novicida U112 protein-disulfide isomerase YP_898416.1 828083 R 401614 CDS YP_898417.1 118497367 4547579 complement(829225..829515) 1 NC_008601.1 hypothetical protein 829515 4547579 FTN_0772 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898417.1 829225 R 401614 CDS YP_898418.1 118497368 4547580 complement(829603..830691) 1 NC_008601.1 4Fe-4S ferredoxin 830691 4547580 FTN_0773 Francisella tularensis subsp. novicida U112 4Fe-4S ferredoxin YP_898418.1 829603 R 401614 CDS YP_898419.1 118497369 4547581 complement(830694..831029) 1 NC_008601.1 hypothetical protein 831029 4547581 FTN_0774 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898419.1 830694 R 401614 CDS YP_898420.1 118497370 4547582 831132..831467 1 NC_008601.1 hypothetical protein 831467 4547582 FTN_0775 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898420.1 831132 D 401614 CDS YP_898421.1 118497371 4547583 831494..833560 1 NC_008601.1 DNA/RNA helicase superfamily I protein 833560 4547583 FTN_0776 Francisella tularensis subsp. novicida U112 DNA/RNA helicase superfamily I protein YP_898421.1 831494 D 401614 CDS YP_898422.1 118497372 4547584 complement(833557..834003) 1 NC_008601.1 hypothetical protein 834003 4547584 FTN_0777 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898422.1 833557 R 401614 CDS YP_898423.1 118497373 4547585 834159..836756 1 NC_008601.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 836756 alaS 4547585 alaS Francisella tularensis subsp. novicida U112 alanyl-tRNA synthetase YP_898423.1 834159 D 401614 CDS YP_898424.1 118497374 4547586 836764..838146 1 NC_008601.1 hypothetical protein 838146 4547586 FTN_0779 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898424.1 836764 D 401614 CDS YP_898425.1 118497375 4547587 838149..839528 1 NC_008601.1 cytosol aminopeptidase 839528 pepB 4547587 pepB Francisella tularensis subsp. novicida U112 cytosol aminopeptidase YP_898425.1 838149 D 401614 CDS YP_898426.1 118497376 4547320 839608..840627 1 NC_008601.1 transaldolase B 840627 talA 4547320 talA Francisella tularensis subsp. novicida U112 transaldolase B YP_898426.1 839608 D 401614 CDS YP_898427.1 118497377 4547321 840650..841225 1 NC_008601.1 hypothetical protein 841225 4547321 FTN_0782 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898427.1 840650 D 401614 CDS YP_898428.1 118497378 4547322 complement(841263..841751) 1 NC_008601.1 isochorismatase family protein 841751 4547322 FTN_0783 Francisella tularensis subsp. novicida U112 isochorismatase family protein YP_898428.1 841263 R 401614 CDS YP_898429.1 118497379 4547324 complement(842439..842945) 1 NC_008601.1 isochorismatase family protein 842945 4547324 FTN_0785 Francisella tularensis subsp. novicida U112 isochorismatase family protein YP_898429.1 842439 R 401614 CDS YP_898430.1 118497380 4547325 843533..844279 1 NC_008601.1 hypothetical protein 844279 4547325 FTN_0786 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898430.1 843533 D 401614 CDS YP_898431.1 118497381 4547326 844273..846288 1 NC_008601.1 UvrD/REP superfamily I DNA/RNA helicase 846288 rep 4547326 rep Francisella tularensis subsp. novicida U112 UvrD/REP superfamily I DNA/RNA helicase YP_898431.1 844273 D 401614 CDS YP_898432.1 118497382 4547327 846344..847174 1 NC_008601.1 hypothetical protein 847174 4547327 FTN_0788 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898432.1 846344 D 401614 CDS YP_898433.1 118497383 4547328 complement(847642..848631) 1 NC_008601.1 putative rhodanese, sulfurtransferase 848631 4547328 FTN_0789 Francisella tularensis subsp. novicida U112 putative rhodanese, sulfurtransferase YP_898433.1 847642 R 401614 CDS YP_898434.1 118497384 4547329 848825..849685 1 NC_008601.1 Required for efficient pilin antigenic variation; recombination associated protein 849685 rdgC 4547329 rdgC Francisella tularensis subsp. novicida U112 recombination associated protein YP_898434.1 848825 D 401614 CDS YP_898435.1 118497385 4547330 849690..849947 1 NC_008601.1 hypothetical protein 849947 4547330 FTN_0791 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898435.1 849690 D 401614 CDS YP_898436.1 118497386 4547331 complement(849963..850385) 1 NC_008601.1 hypothetical protein 850385 4547331 FTN_0792 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898436.1 849963 R 401614 CDS YP_898437.1 118497387 4547332 850477..851046 1 NC_008601.1 hypothetical protein 851046 4547332 FTN_0793 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898437.1 850477 D 401614 CDS YP_898438.1 118497388 4547334 complement(852098..852310) 1 NC_008601.1 transcriptional regulator 852310 4547334 FTN_0795 Francisella tularensis subsp. novicida U112 transcriptional regulator YP_898438.1 852098 R 401614 CDS YP_898439.1 118497389 4547336 853524..854072 1 NC_008601.1 fatty acid hydroxylase 854072 4547336 FTN_0797 Francisella tularensis subsp. novicida U112 fatty acid hydroxylase YP_898439.1 853524 D 401614 CDS YP_898440.1 118497390 4547337 854146..856302 1 NC_008601.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 856302 rlmL 4547337 rlmL Francisella tularensis subsp. novicida U112 23S rRNA m(2)G2445 methyltransferase YP_898440.1 854146 D 401614 CDS YP_898441.1 118497391 4548312 complement(856314..856643) 1 NC_008601.1 putative membrane transporter of cations and cationic drugs, multidrug resistance protein 856643 emrE 4548312 emrE Francisella tularensis subsp. novicida U112 putative membrane transporter of cations and cationic drugs, multidrug resistance protein YP_898441.1 856314 R 401614 CDS YP_898442.1 118497392 4548313 complement(857559..858587) 1 NC_008601.1 ArsB arsenite/antimonite exporter 858587 4548313 FTN_0800 Francisella tularensis subsp. novicida U112 ArsB arsenite/antimonite exporter YP_898442.1 857559 R 401614 CDS YP_898443.1 118497393 4548314 complement(858597..858947) 1 NC_008601.1 ArsR family transcriptional regulator 858947 4548314 FTN_0801 Francisella tularensis subsp. novicida U112 ArsR family transcriptional regulator YP_898443.1 858597 R 401614 CDS YP_898444.1 118497394 4548315 859091..859489 1 NC_008601.1 hypothetical protein 859489 4548315 FTN_0802 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898444.1 859091 D 401614 CDS YP_898445.1 118497395 4548316 859494..860435 1 NC_008601.1 methionyl-tRNA formyltransferase 860435 fmt 4548316 fmt Francisella tularensis subsp. novicida U112 methionyl-tRNA formyltransferase YP_898445.1 859494 D 401614 CDS YP_898446.1 118497396 4548317 860439..861413 1 NC_008601.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 861413 gshB 4548317 gshB Francisella tularensis subsp. novicida U112 glutathione synthetase YP_898446.1 860439 D 401614 CDS YP_898447.1 118497397 4548318 861403..862704 1 NC_008601.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 862704 hemL 4548318 hemL Francisella tularensis subsp. novicida U112 glutamate-1-semialdehyde aminotransferase YP_898447.1 861403 D 401614 CDS YP_898448.1 118497398 4548319 complement(862720..864387) 1 NC_008601.1 glycosyl hydrolase family protein 864387 4548319 FTN_0806 Francisella tularensis subsp. novicida U112 glycosyl hydrolase family protein YP_898448.1 862720 R 401614 CDS YP_898449.1 118497399 4548320 complement(864448..865230) 1 NC_008601.1 short chain dehydrogenase 865230 4548320 FTN_0807 Francisella tularensis subsp. novicida U112 short chain dehydrogenase YP_898449.1 864448 R 401614 CDS YP_898450.1 118497400 4548321 complement(865252..865992) 1 NC_008601.1 converts acetoacetate to acetone and carbon dioxide; acetoacetate decarboxylase 865992 4548321 FTN_0808 Francisella tularensis subsp. novicida U112 acetoacetate decarboxylase YP_898450.1 865252 R 401614 CDS YP_898451.1 118497401 4548322 866270..867520 1 NC_008601.1 fucose: H+ symporter (FHS) family protein 867520 4548322 FTN_0809 Francisella tularensis subsp. novicida U112 fucose: H+ symporter (FHS) family protein YP_898451.1 866270 D 401614 CDS YP_898452.1 118497402 4548323 867532..868416 1 NC_008601.1 ROK family protein 868416 4548323 FTN_0810 Francisella tularensis subsp. novicida U112 ROK family protein YP_898452.1 867532 D 401614 CDS YP_898453.1 118497403 4548324 868439..869401 1 NC_008601.1 biotin--acetyl-CoA-carboxylase ligase 869401 birA 4548324 birA Francisella tularensis subsp. novicida U112 biotin--acetyl-CoA-carboxylase ligase YP_898453.1 868439 D 401614 CDS YP_898454.1 118497404 4548325 complement(869344..870021) 1 NC_008601.1 dethiobiotin synthetase 870021 bioD 4548325 bioD Francisella tularensis subsp. novicida U112 dethiobiotin synthetase YP_898454.1 869344 R 401614 CDS YP_898455.1 118497405 4548326 complement(870026..870763) 1 NC_008601.1 biotin synthesis protein BioC 870763 bioC 4548326 bioC Francisella tularensis subsp. novicida U112 biotin synthesis protein BioC YP_898455.1 870026 R 401614 CDS YP_898456.1 118497406 4548327 complement(870741..871868) 1 NC_008601.1 8-amino-7-oxononanoate synthase 871868 bioF 4548327 bioF Francisella tularensis subsp. novicida U112 8-amino-7-oxononanoate synthase YP_898456.1 870741 R 401614 CDS YP_898457.1 118497407 4548328 complement(871862..872803) 1 NC_008601.1 biotin synthase 872803 bioB 4548328 bioB Francisella tularensis subsp. novicida U112 biotin synthase YP_898457.1 871862 R 401614 CDS YP_898458.1 118497408 4548329 872849..874180 1 NC_008601.1 adenosylmethionine-8-amino-7-oxononanoate aminotransferase 874180 bioA 4548329 bioA Francisella tularensis subsp. novicida U112 adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_898458.1 872849 D 401614 CDS YP_898459.1 118497409 4547797 complement(874182..874682) 1 NC_008601.1 hypothetical protein 874682 4547797 FTN_0817 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898459.1 874182 R 401614 CDS YP_898460.1 118497410 4547798 complement(874698..875618) 1 NC_008601.1 lipase/esterase 875618 4547798 FTN_0818 Francisella tularensis subsp. novicida U112 lipase/esterase YP_898460.1 874698 R 401614 CDS YP_898461.1 118497411 4547799 complement(875631..876896) 1 NC_008601.1 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase/dihydropteroate synthase 876896 4547799 FTN_0819 Francisella tularensis subsp. novicida U112 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase/dihydropteroate synthase YP_898461.1 875631 R 401614 CDS YP_898462.1 118497412 4547800 complement(876898..877251) 1 NC_008601.1 dihydroneopterin aldolase 877251 folB 4547800 folB Francisella tularensis subsp. novicida U112 dihydroneopterin aldolase YP_898462.1 876898 R 401614 CDS YP_898463.1 118497413 4547801 877333..878703 1 NC_008601.1 AMP-binding protein 878703 4547801 FTN_0821 Francisella tularensis subsp. novicida U112 AMP-binding protein YP_898463.1 877333 D 401614 CDS YP_898464.1 118497414 4547802 878696..880459 1 NC_008601.1 para-aminobenzoate synthase component I 880459 4547802 FTN_0822 Francisella tularensis subsp. novicida U112 para-aminobenzoate synthase component I YP_898464.1 878696 D 401614 CDS YP_898465.1 118497415 4547803 880461..881015 1 NC_008601.1 anthranilate synthase component II 881015 pabA 4547803 pabA Francisella tularensis subsp. novicida U112 anthranilate synthase component II YP_898465.1 880461 D 401614 CDS YP_898466.1 118497416 4547804 complement(881016..882230) 1 NC_008601.1 major facilitator transporter 882230 4547804 FTN_0824 Francisella tularensis subsp. novicida U112 major facilitator transporter YP_898466.1 881016 R 401614 CDS YP_898467.1 118497417 4547805 complement(882247..883320) 1 NC_008601.1 aldo/keto reductase family protein 883320 4547805 FTN_0825 Francisella tularensis subsp. novicida U112 aldo/keto reductase family protein YP_898467.1 882247 R 401614 CDS YP_898468.1 118497418 4547806 complement(883399..884463) 1 NC_008601.1 aldo/keto reductase family protein 884463 4547806 FTN_0826 Francisella tularensis subsp. novicida U112 aldo/keto reductase family protein YP_898468.1 883399 R 401614 CDS YP_898469.1 118497419 4547807 complement(884555..885481) 1 NC_008601.1 carbon-nitrogen hydrolase family protein 885481 4547807 FTN_0827 Francisella tularensis subsp. novicida U112 carbon-nitrogen hydrolase family protein YP_898469.1 884555 R 401614 CDS YP_898470.1 118497420 4547808 complement(885559..885984) 1 NC_008601.1 hypothetical protein 885984 4547808 FTN_0828 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898470.1 885559 R 401614 CDS YP_898471.1 118497421 4547809 complement(886123..886842) 1 NC_008601.1 hypothetical protein 886842 4547809 FTN_0829 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898471.1 886123 R 401614 CDS YP_898472.1 118497422 4547810 complement(886832..887452) 1 NC_008601.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 887452 folE 4547810 folE Francisella tularensis subsp. novicida U112 GTP cyclohydrolase I YP_898472.1 886832 R 401614 CDS YP_898473.1 118497423 4547811 887579..888904 1 NC_008601.1 ATP-dependent RNA helicase 888904 4547811 FTN_0831 Francisella tularensis subsp. novicida U112 ATP-dependent RNA helicase YP_898473.1 887579 D 401614 CDS YP_898474.1 118497424 4547812 complement(888901..890442) 1 NC_008601.1 proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter 890442 4547812 FTN_0832 Francisella tularensis subsp. novicida U112 proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter YP_898474.1 888901 R 401614 CDS YP_898475.1 118497425 4547813 complement(890580..890900) 1 NC_008601.1 hypothetical protein 890900 4547813 FTN_0833 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898475.1 890580 R 401614 CDS YP_898476.1 118497426 4547814 complement(890911..892272) 1 NC_008601.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 892272 gor 4547814 gor Francisella tularensis subsp. novicida U112 glutathione reductase YP_898476.1 890911 R 401614 CDS YP_898477.1 118497427 4547815 complement(892308..893027) 1 NC_008601.1 hypothetical protein 893027 4547815 FTN_0835 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898477.1 892308 R 401614 CDS YP_898478.1 118497428 4547816 complement(893027..893530) 1 NC_008601.1 kinase-like protein 893530 4547816 FTN_0836 Francisella tularensis subsp. novicida U112 kinase-like protein YP_898478.1 893027 R 401614 CDS YP_898479.1 118497429 4548629 complement(893530..894228) 1 NC_008601.1 hypothetical protein 894228 4548629 FTN_0837 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898479.1 893530 R 401614 CDS YP_898480.1 118497430 4548630 complement(894229..895017) 1 NC_008601.1 exodeoxyribonuclease III 895017 xthA 4548630 xthA Francisella tularensis subsp. novicida U112 exodeoxyribonuclease III YP_898480.1 894229 R 401614 CDS YP_898481.1 118497431 4548631 895194..896294 1 NC_008601.1 hypothetical protein 896294 4548631 FTN_0839 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898481.1 895194 D 401614 CDS YP_898482.1 118497432 4548632 896313..896903 1 NC_008601.1 NADPH-quinone reductase 896903 mdaB 4548632 mdaB Francisella tularensis subsp. novicida U112 NADPH-quinone reductase YP_898482.1 896313 D 401614 CDS YP_898483.1 118497433 4548633 897004..897681 1 NC_008601.1 ThiJ/PfpI family protein 897681 4548633 FTN_0841 Francisella tularensis subsp. novicida U112 ThiJ/PfpI family protein YP_898483.1 897004 D 401614 CDS YP_898484.1 118497434 4548634 complement(897751..898863) 1 NC_008601.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 898863 aroG 4548634 aroG Francisella tularensis subsp. novicida U112 phospho-2-dehydro-3-deoxyheptonate aldolase YP_898484.1 897751 R 401614 CDS YP_898485.1 118497435 4548635 complement(898895..900271) 1 NC_008601.1 signal recognition particle GTPase 900271 ffh 4548635 ffh Francisella tularensis subsp. novicida U112 signal recognition particle GTPase YP_898485.1 898895 R 401614 CDS YP_898486.1 118497436 4548636 complement(900352..900618) 1 NC_008601.1 hypothetical protein 900618 4548636 FTN_0844 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898486.1 900352 R 401614 CDS YP_898487.1 118497437 4548637 complement(900618..901457) 1 NC_008601.1 hypothetical protein 901457 4548637 FTN_0845 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898487.1 900618 R 401614 CDS YP_898488.1 118497438 4548638 901617..901835 1 NC_008601.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 901835 infA 4548638 infA Francisella tularensis subsp. novicida U112 translation initiation factor IF-1 YP_898488.1 901617 D 401614 CDS YP_898489.1 118497439 4548639 complement(901864..902790) 1 NC_008601.1 hypothetical protein 902790 4548639 FTN_0847 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898489.1 901864 R 401614 CDS YP_898490.1 118497440 4548640 complement(902795..904216) 1 NC_008601.1 amino acid antiporter 904216 4548640 FTN_0848 Francisella tularensis subsp. novicida U112 amino acid antiporter YP_898490.1 902795 R 401614 CDS YP_898491.1 118497441 4548641 complement(904275..905648) 1 NC_008601.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein 905648 trkA 4548641 trkA Francisella tularensis subsp. novicida U112 potassium transporter peripheral membrane protein YP_898491.1 904275 R 401614 CDS YP_898492.1 118497442 4548642 905800..906210 1 NC_008601.1 transcriptional regulator 906210 4548642 FTN_0850 Francisella tularensis subsp. novicida U112 transcriptional regulator YP_898492.1 905800 D 401614 CDS YP_898493.1 118497443 4548643 906217..907662 1 NC_008601.1 with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB 907662 sufB 4548643 sufB Francisella tularensis subsp. novicida U112 cysteine desulfurase activator complex subunit SufB YP_898493.1 906217 D 401614 CDS YP_898494.1 118497444 4548644 907701..908450 1 NC_008601.1 sufS activator complex, sufC subunit 908450 sufC 4548644 sufC Francisella tularensis subsp. novicida U112 sufS activator complex, sufC subunit YP_898494.1 907701 D 401614 CDS YP_898495.1 118497445 4548645 908463..909608 1 NC_008601.1 sufS activator complex, sufD subunit 909608 sufD 4548645 sufD Francisella tularensis subsp. novicida U112 sufS activator complex, sufD subunit YP_898495.1 908463 D 401614 CDS YP_898496.1 118497446 4548646 909700..910482 1 NC_008601.1 hypothetical protein 910482 4548646 FTN_0854 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898496.1 909700 D 401614 CDS YP_898497.1 118497447 4548647 910576..911265 1 NC_008601.1 hypothetical protein 911265 4548647 FTN_0855 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898497.1 910576 D 401614 CDS YP_898498.1 118497448 4547224 911269..911595 1 NC_008601.1 thioredoxin 911595 4547224 FTN_0856 Francisella tularensis subsp. novicida U112 thioredoxin YP_898498.1 911269 D 401614 CDS YP_898499.1 118497449 4547225 911588..912037 1 NC_008601.1 hypothetical protein 912037 4547225 FTN_0857 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898499.1 911588 D 401614 CDS YP_898500.1 118497450 4547226 complement(911996..912289) 1 NC_008601.1 MarR family transcriptional regulator 912289 4547226 FTN_0858 Francisella tularensis subsp. novicida U112 MarR family transcriptional regulator YP_898500.1 911996 R 401614 CDS YP_898501.1 118497451 4547227 complement(912293..912898) 1 NC_008601.1 hypothetical protein 912898 4547227 FTN_0859 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898501.1 912293 R 401614 CDS YP_898502.1 118497452 4547228 complement(912964..914316) 1 NC_008601.1 amino acid transporter (AAT) family protein 914316 4547228 FTN_0860 Francisella tularensis subsp. novicida U112 amino acid transporter (AAT) family protein YP_898502.1 912964 R 401614 CDS YP_898503.1 118497453 4547229 914550..915791 1 NC_008601.1 hypothetical protein 915791 4547229 FTN_0861 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898503.1 914550 D 401614 CDS YP_898504.1 118497454 4547230 916124..917248 1 NC_008601.1 hypothetical protein 917248 4547230 FTN_0862 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898504.1 916124 D 401614 CDS YP_898505.1 118497455 4547231 917341..917778 1 NC_008601.1 hypothetical protein 917778 4547231 FTN_0863 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898505.1 917341 D 401614 CDS YP_898506.1 118497456 4547232 918329..918700 1 NC_008601.1 hypothetical protein 918700 4547232 FTN_0864 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898506.1 918329 D 401614 CDS YP_898507.1 118497457 4547233 complement(918872..919291) 1 NC_008601.1 mutator protein 919291 mutT 4547233 mutT Francisella tularensis subsp. novicida U112 mutator protein YP_898507.1 918872 R 401614 CDS YP_898508.1 118497458 4547234 919330..919914 1 NC_008601.1 hypothetical protein 919914 4547234 FTN_0866 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898508.1 919330 D 401614 CDS YP_898509.1 118497459 4547235 919916..920326 1 NC_008601.1 hypothetical protein 920326 4547235 FTN_0867 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898509.1 919916 D 401614 CDS YP_898510.1 118497460 4547236 920419..920997 1 NC_008601.1 membrane protein 920997 4547236 FTN_0868 Francisella tularensis subsp. novicida U112 membrane protein YP_898510.1 920419 D 401614 CDS YP_898511.1 118497461 4547237 921132..923027 1 NC_008601.1 hypothetical protein 923027 4547237 FTN_0869 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898511.1 921132 D 401614 CDS YP_898512.1 118497462 4547238 923135..925576 1 NC_008601.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 925576 leuS 4547238 leuS Francisella tularensis subsp. novicida U112 leucyl-tRNA synthetase YP_898512.1 923135 D 401614 CDS YP_898513.1 118497463 4547239 925584..926159 1 NC_008601.1 rare lipoprotein B family protein 926159 4547239 FTN_0871 Francisella tularensis subsp. novicida U112 rare lipoprotein B family protein YP_898513.1 925584 D 401614 CDS YP_898514.1 118497464 4547240 926220..927410 1 NC_008601.1 small conductance mechanosensitive ion channel (MscS) family protein 927410 4547240 FTN_0872 Francisella tularensis subsp. novicida U112 small conductance mechanosensitive ion channel (MscS) family protein YP_898514.1 926220 D 401614 CDS YP_898515.1 118497465 4547241 complement(927417..927983) 1 NC_008601.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 927983 dcd 4547241 dcd Francisella tularensis subsp. novicida U112 deoxycytidine triphosphate deaminase YP_898515.1 927417 R 401614 CDS YP_898516.1 118497466 4547242 complement(927995..928855) 1 NC_008601.1 nucleotide-binding protein 928855 4547242 FTN_0874 Francisella tularensis subsp. novicida U112 nucleotide-binding protein YP_898516.1 927995 R 401614 CDS YP_898517.1 118497467 4547243 928929..930161 1 NC_008601.1 major facilitator superfamily metabolite/H(+) symporter 930161 4547243 FTN_0875 Francisella tularensis subsp. novicida U112 major facilitator superfamily metabolite/H(+) symporter YP_898517.1 928929 D 401614 CDS YP_898518.1 118497468 4548820 930215..931642 1 NC_008601.1 cardiolipin synthase 931642 4548820 FTN_0876 Francisella tularensis subsp. novicida U112 cardiolipin synthase YP_898518.1 930215 D 401614 CDS YP_898519.1 118497469 4548821 931734..933164 1 NC_008601.1 cardiolipin synthetase 933164 cls 4548821 cls Francisella tularensis subsp. novicida U112 cardiolipin synthetase YP_898519.1 931734 D 401614 CDS YP_898520.1 118497470 4548822 933333..934322 1 NC_008601.1 hypothetical protein 934322 4548822 FTN_0878 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898520.1 933333 D 401614 CDS YP_898521.1 118497471 4548823 complement(934344..935090) 1 NC_008601.1 zinc (Zn2+)-iron (Fe2+) permease (ZIP) family protein 935090 4548823 FTN_0879 Francisella tularensis subsp. novicida U112 zinc (Zn2+)-iron (Fe2+) permease (ZIP) family protein YP_898521.1 934344 R 401614 CDS YP_898522.1 118497472 4548824 complement(935093..936310) 1 NC_008601.1 hypothetical protein 936310 4548824 FTN_0880 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898522.1 935093 R 401614 CDS YP_898523.1 118497473 4548825 936452..936883 1 NC_008601.1 Fe2+/Zn2+ uptake regulator protein 936883 4548825 FTN_0881 Francisella tularensis subsp. novicida U112 Fe2+/Zn2+ uptake regulator protein YP_898523.1 936452 D 401614 CDS YP_898524.1 118497474 4548826 complement(936926..939298) 1 NC_008601.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 939298 pheT 4548826 pheT Francisella tularensis subsp. novicida U112 phenylalanyl-tRNA synthetase subunit beta YP_898524.1 936926 R 401614 CDS YP_898525.1 118497475 4548827 complement(939318..940331) 1 NC_008601.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 940331 pheS 4548827 pheS Francisella tularensis subsp. novicida U112 phenylalanyl-tRNA synthetase subunit alpha YP_898525.1 939318 R 401614 CDS YP_898526.1 118497476 4548828 complement(940417..941310) 1 NC_008601.1 drug/metabolite transporter superfamily protein 941310 4548828 FTN_0884 Francisella tularensis subsp. novicida U112 drug/metabolite transporter superfamily protein YP_898526.1 940417 R 401614 CDS YP_898527.1 118497477 4548829 complement(941335..942810) 1 NC_008601.1 proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter 942810 4548829 FTN_0885 Francisella tularensis subsp. novicida U112 proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter YP_898527.1 941335 R 401614 CDS YP_898528.1 118497478 4548830 942996..944264 1 NC_008601.1 sugar:cation symporter family protein 944264 4548830 FTN_0886 Francisella tularensis subsp. novicida U112 sugar:cation symporter family protein YP_898528.1 942996 D 401614 CDS YP_898529.1 118497479 4548831 complement(944249..945208) 1 NC_008601.1 hypothetical protein 945208 4548831 FTN_0887 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898529.1 944249 R 401614 CDS YP_898530.1 118497480 4548832 945336..945872 1 NC_008601.1 hypothetical protein 945872 4548832 FTN_0888 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898530.1 945336 D 401614 CDS YP_898531.1 118497481 4548833 945887..946090 1 NC_008601.1 transcriptional regulator 946090 4548833 FTN_0889 Francisella tularensis subsp. novicida U112 transcriptional regulator YP_898531.1 945887 D 401614 CDS YP_898532.1 118497482 4548834 946569..947336 1 NC_008601.1 hypothetical protein 947336 4548834 FTN_0890 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898532.1 946569 D 401614 CDS YP_898533.1 118497483 4548835 complement(947378..948424) 1 NC_008601.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 948424 ruvB 4548835 ruvB Francisella tularensis subsp. novicida U112 Holliday junction DNA helicase RuvB YP_898533.1 947378 R 401614 CDS YP_898534.1 118497484 4548836 complement(948488..949213) 1 NC_008601.1 short chain dehydrogenase family protein 949213 4548836 FTN_0892 Francisella tularensis subsp. novicida U112 short chain dehydrogenase family protein YP_898534.1 948488 R 401614 CDS YP_898535.1 118497485 4548837 949331..949921 1 NC_008601.1 hypothetical protein 949921 4548837 FTN_0893 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898535.1 949331 D 401614 CDS YP_898536.1 118497486 4548838 complement(949931..950560) 1 NC_008601.1 GDSL-like lipolytic enzyme 950560 4548838 FTN_0894 Francisella tularensis subsp. novicida U112 GDSL-like lipolytic enzyme YP_898536.1 949931 R 401614 CDS YP_898537.1 118497487 4547741 complement(950582..950917) 1 NC_008601.1 hypothetical protein 950917 4547741 FTN_0895 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898537.1 950582 R 401614 CDS YP_898538.1 118497488 4547742 complement(950933..952780) 1 NC_008601.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 952780 dxs 4547742 dxs Francisella tularensis subsp. novicida U112 1-deoxy-D-xylulose-5-phosphate synthase YP_898538.1 950933 R 401614 CDS YP_898539.1 118497489 4547743 complement(952862..954412) 1 NC_008601.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 954412 guaA 4547743 guaA Francisella tularensis subsp. novicida U112 GMP synthase YP_898539.1 952862 R 401614 CDS YP_898540.1 118497490 4547744 complement(954500..956044) 1 NC_008601.1 amino acid permease 956044 4547744 FTN_0898 Francisella tularensis subsp. novicida U112 amino acid permease YP_898540.1 954500 R 401614 CDS YP_898541.1 118497491 4547745 complement(956100..956876) 1 NC_008601.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 956876 truA 4547745 truA Francisella tularensis subsp. novicida U112 tRNA pseudouridine synthase A YP_898541.1 956100 R 401614 CDS YP_898542.1 118497492 4547746 complement(956879..958711) 1 NC_008601.1 hypothetical protein 958711 4547746 FTN_0900 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898542.1 956879 R 401614 CDS YP_898543.1 118497493 4547747 complement(958724..959317) 1 NC_008601.1 fumarylacetoacetate hydrolase family protein 959317 4547747 FTN_0901 Francisella tularensis subsp. novicida U112 fumarylacetoacetate hydrolase family protein YP_898543.1 958724 R 401614 CDS YP_898544.1 118497494 4547748 complement(959366..960097) 1 NC_008601.1 ABC transporter ATP-binding protein 960097 yhbG 4547748 yhbG Francisella tularensis subsp. novicida U112 ABC transporter ATP-binding protein YP_898544.1 959366 R 401614 CDS YP_898545.1 118497495 4547749 complement(960171..961004) 1 NC_008601.1 hypothetical protein 961004 4547749 FTN_0903 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898545.1 960171 R 401614 CDS YP_898546.1 118497496 4547750 complement(960991..961617) 1 NC_008601.1 hypothetical protein 961617 4547750 FTN_0904 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898546.1 960991 R 401614 CDS YP_898547.1 118497497 4547751 complement(961625..962173) 1 NC_008601.1 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase 962173 yrbI 4547751 yrbI Francisella tularensis subsp. novicida U112 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase YP_898547.1 961625 R 401614 CDS YP_898548.1 118497498 4547752 complement(962264..962785) 1 NC_008601.1 inorganic pyrophosphatase 962785 ppa 4547752 ppa Francisella tularensis subsp. novicida U112 inorganic pyrophosphatase YP_898548.1 962264 R 401614 CDS YP_898549.1 118497499 4547753 962942..964276 1 NC_008601.1 D-alanyl-D-alanine carboxypeptidase 964276 4547753 FTN_0907 Francisella tularensis subsp. novicida U112 D-alanyl-D-alanine carboxypeptidase YP_898549.1 962942 D 401614 CDS YP_898550.1 118497500 4547754 964309..964593 1 NC_008601.1 hypothetical protein 964593 4547754 FTN_0908 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898550.1 964309 D 401614 CDS YP_898551.1 118497501 4547755 964603..965223 1 NC_008601.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 965223 lipB 4547755 lipB Francisella tularensis subsp. novicida U112 lipoate-protein ligase B YP_898551.1 964603 D 401614 CDS YP_898552.1 118497502 4547756 965706..967178 1 NC_008601.1 sugar:cation symporter family protein 967178 4547756 FTN_0910 Francisella tularensis subsp. novicida U112 sugar:cation symporter family protein YP_898552.1 965706 D 401614 CDS YP_898553.1 118497503 4547757 967156..969195 1 NC_008601.1 alpha-glucosidase 969195 4547757 FTN_0911 Francisella tularensis subsp. novicida U112 alpha-glucosidase YP_898553.1 967156 D 401614 CDS YP_898554.1 118497504 4547758 complement(969308..970570) 1 NC_008601.1 NADH dehydrogenase 970570 ndh 4547758 ndh Francisella tularensis subsp. novicida U112 NADH dehydrogenase YP_898554.1 969308 R 401614 CDS YP_898555.1 118497505 4547759 complement(970677..972410) 1 NC_008601.1 RNA polymerase sigma-70 factor 972410 rpoD 4547759 rpoD Francisella tularensis subsp. novicida U112 RNA polymerase sigma-70 factor YP_898555.1 970677 R 401614 CDS YP_898556.1 118497506 4547760 complement(972435..974252) 1 NC_008601.1 DNA primase 974252 dnaG 4547760 dnaG Francisella tularensis subsp. novicida U112 DNA primase YP_898556.1 972435 R 401614 CDS YP_898557.1 118497507 4548256 complement(974273..974719) 1 NC_008601.1 hypothetical protein 974719 4548256 FTN_0915 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898557.1 974273 R 401614 CDS YP_898558.1 118497508 4548257 complement(974780..974977) 1 NC_008601.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 974977 rpsU 4548257 rpsU Francisella tularensis subsp. novicida U112 30S ribosomal protein S21 YP_898558.1 974780 R 401614 CDS YP_898559.1 118497509 4548258 975232..976635 1 NC_008601.1 serine-type D-Ala-D-Ala carboxypeptidase 976635 4548258 FTN_0917 Francisella tularensis subsp. novicida U112 serine-type D-Ala-D-Ala carboxypeptidase YP_898559.1 975232 D 401614 CDS YP_898560.1 118497510 4548259 976636..977247 1 NC_008601.1 hypothetical protein 977247 4548259 FTN_0918 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898560.1 976636 D 401614 CDS YP_898561.1 118497511 4548260 977263..977679 1 NC_008601.1 hypothetical protein 977679 4548260 FTN_0919 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898561.1 977263 D 401614 CDS YP_898562.1 118497512 4548261 977672..978475 1 NC_008601.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 978475 4548261 FTN_0920 Francisella tularensis subsp. novicida U112 C32 tRNA thiolase YP_898562.1 977672 D 401614 CDS YP_898563.1 118497513 4548262 978489..979340 1 NC_008601.1 FKBP-type peptidyl-prolyl cis-trans isomerase 979340 4548262 FTN_0921 Francisella tularensis subsp. novicida U112 FKBP-type peptidyl-prolyl cis-trans isomerase YP_898563.1 978489 D 401614 CDS YP_898564.1 118497514 4548263 complement(979358..980335) 1 NC_008601.1 octaprenyl diphosphate synthase 980335 ispB 4548263 ispB Francisella tularensis subsp. novicida U112 octaprenyl diphosphate synthase YP_898564.1 979358 R 401614 CDS YP_898565.1 118497515 4548264 complement(980424..980855) 1 NC_008601.1 hypothetical protein 980855 4548264 FTN_0923 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898565.1 980424 R 401614 CDS YP_898566.1 118497516 4548265 complement(980936..981559) 1 NC_008601.1 hypothetical protein 981559 4548265 FTN_0924 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898566.1 980936 R 401614 CDS YP_898567.1 118497517 4548266 complement(982220..983200) 1 NC_008601.1 hypothetical protein 983200 4548266 FTN_0925 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898567.1 982220 R 401614 CDS YP_898568.1 118497518 4548267 complement(983652..984254) 1 NC_008601.1 adenylylsulfate kinase 984254 cysC 4548267 cysC Francisella tularensis subsp. novicida U112 adenylylsulfate kinase YP_898568.1 983652 R 401614 CDS YP_898569.1 118497519 4548268 complement(984274..985686) 1 NC_008601.1 sulfate adenylyltransferase 985686 cysN 4548268 cysN Francisella tularensis subsp. novicida U112 sulfate adenylyltransferase YP_898569.1 984274 R 401614 CDS YP_898570.1 118497520 4548269 complement(988922..989818) 1 NC_008601.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 989818 cysD 4548269 cysD Francisella tularensis subsp. novicida U112 sulfate adenylyltransferase subunit 2 YP_898570.1 988922 R 401614 CDS YP_898571.1 118497521 4548270 complement(989842..990945) 1 NC_008601.1 hypothetical protein 990945 4548270 FTN_0929 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898571.1 989842 R 401614 CDS YP_898572.1 118497522 4548271 complement(990926..991774) 1 NC_008601.1 hypothetical protein 991774 4548271 FTN_0930 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898572.1 990926 R 401614 CDS YP_898573.1 118497523 4548272 991793..992752 1 NC_008601.1 hypothetical protein 992752 4548272 FTN_0931 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898573.1 991793 D 401614 CDS YP_898574.1 118497524 4548273 992752..994551 1 NC_008601.1 ABC transporter ATP-binding protein 994551 4548273 FTN_0932 Francisella tularensis subsp. novicida U112 ABC transporter ATP-binding protein YP_898574.1 992752 D 401614 CDS YP_898575.1 118497525 4547530 994548..994832 1 NC_008601.1 hypothetical protein 994832 4547530 FTN_0933 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898575.1 994548 D 401614 CDS YP_898576.1 118497526 4547531 994829..995323 1 NC_008601.1 hypothetical protein 995323 4547531 FTN_0934 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898576.1 994829 D 401614 CDS YP_898577.1 118497527 4547532 995336..997189 1 NC_008601.1 asparagine synthase 997189 asnB 4547532 asnB Francisella tularensis subsp. novicida U112 asparagine synthase YP_898577.1 995336 D 401614 CDS YP_898578.1 118497528 4547533 997186..998418 1 NC_008601.1 hypothetical protein 998418 4547533 FTN_0936 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898578.1 997186 D 401614 CDS YP_898579.1 118497529 4547534 998435..999337 1 NC_008601.1 hypothetical protein 999337 4547534 FTN_0937 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898579.1 998435 D 401614 CDS YP_898580.1 118497530 4547535 complement(999435..999626) 1 NC_008601.1 hypothetical protein 999626 4547535 FTN_0938 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898580.1 999435 R 401614 CDS YP_898581.1 118497531 4547536 complement(1000019..1000177) 1 NC_008601.1 hypothetical protein 1000177 4547536 FTN_0939 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898581.1 1000019 R 401614 CDS YP_898582.1 118497532 4547537 complement(1000693..1000887) 1 NC_008601.1 hypothetical protein 1000887 4547537 FTN_0940 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898582.1 1000693 R 401614 CDS YP_898583.1 118497533 4547538 complement(1001160..1001330) 1 NC_008601.1 hypothetical protein 1001330 4547538 FTN_0941 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898583.1 1001160 R 401614 CDS YP_898584.1 118497534 4547539 complement(1001367..1001510) 1 NC_008601.1 hypothetical protein 1001510 4547539 FTN_0942 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898584.1 1001367 R 401614 CDS YP_898585.1 118497535 4547540 complement(1001819..1002259) 1 NC_008601.1 ribosomal-protein-alanine acetyltransferase 1002259 rimI 4547540 rimI Francisella tularensis subsp. novicida U112 ribosomal-protein-alanine acetyltransferase YP_898585.1 1001819 R 401614 CDS YP_898586.1 118497536 4547541 complement(1002237..1002662) 1 NC_008601.1 hypothetical protein 1002662 4547541 FTN_0944 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898586.1 1002237 R 401614 CDS YP_898587.1 118497537 4547542 complement(1002662..1003477) 1 NC_008601.1 16S rRNA pseudouridine synthase 1003477 rsuA 4547542 rsuA Francisella tularensis subsp. novicida U112 16S rRNA pseudouridine synthase YP_898587.1 1002662 R 401614 CDS YP_898588.1 118497538 4547543 complement(1003470..1004375) 1 NC_008601.1 Type IV pili, pilus assembly protein 1004375 pilF 4547543 pilF Francisella tularensis subsp. novicida U112 Type IV pili, pilus assembly protein YP_898588.1 1003470 R 401614 CDS YP_898589.1 118497539 4547544 complement(1004365..1005477) 1 NC_008601.1 radical SAM superfamily protein 1005477 4547544 FTN_0947 Francisella tularensis subsp. novicida U112 radical SAM superfamily protein YP_898589.1 1004365 R 401614 CDS YP_898590.1 118497540 4547545 complement(1005508..1006905) 1 NC_008601.1 replicative DNA helicase 1006905 dnaB 4547545 dnaB Francisella tularensis subsp. novicida U112 replicative DNA helicase YP_898590.1 1005508 R 401614 CDS YP_898591.1 118497541 4547546 complement(1006993..1007448) 1 NC_008601.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 1007448 rplI 4547546 rplI Francisella tularensis subsp. novicida U112 50S ribosomal protein L9 YP_898591.1 1006993 R 401614 CDS YP_898592.1 118497542 4547547 complement(1007467..1007685) 1 NC_008601.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 1007685 rpsR 4547547 rpsR Francisella tularensis subsp. novicida U112 30S ribosomal protein S18 YP_898592.1 1007467 R 401614 CDS YP_898593.1 118497543 4547548 complement(1007701..1008036) 1 NC_008601.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 1008036 rpsF 4547548 rpsF Francisella tularensis subsp. novicida U112 30S ribosomal protein S6 YP_898593.1 1007701 R 401614 CDS YP_898594.1 118497544 4547549 complement(1008162..1008644) 1 NC_008601.1 hypothetical protein 1008644 4547549 FTN_0952 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898594.1 1008162 R 401614 CDS YP_898595.1 118497545 4547244 1008733..1009659 1 NC_008601.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 1009659 hemF 4547244 hemF Francisella tularensis subsp. novicida U112 coproporphyrinogen III oxidase YP_898595.1 1008733 D 401614 CDS YP_898596.1 118497546 4547245 1009684..1010892 1 NC_008601.1 histidine acid phosphatase 1010892 4547245 FTN_0954 Francisella tularensis subsp. novicida U112 histidine acid phosphatase YP_898596.1 1009684 D 401614 CDS YP_898597.1 118497547 4547246 1010967..1012019 1 NC_008601.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 1012019 serC 4547246 serC Francisella tularensis subsp. novicida U112 phosphoserine aminotransferase YP_898597.1 1010967 D 401614 CDS YP_898598.1 118497548 4547247 1012006..1012671 1 NC_008601.1 cytidylate kinase 1012671 cmk 4547247 cmk Francisella tularensis subsp. novicida U112 cytidylate kinase YP_898598.1 1012006 D 401614 CDS YP_898599.1 118497549 4547248 complement(1012688..1013299) 1 NC_008601.1 short chain dehydrogenase 1013299 4547248 FTN_0957 Francisella tularensis subsp. novicida U112 short chain dehydrogenase YP_898599.1 1012688 R 401614 CDS YP_898600.1 118497550 4547249 complement(1013302..1013826) 1 NC_008601.1 AhpC/TSA family protein 1013826 4547249 FTN_0958 Francisella tularensis subsp. novicida U112 AhpC/TSA family protein YP_898600.1 1013302 R 401614 CDS YP_898601.1 118497551 4547250 1013924..1014793 1 NC_008601.1 oxidative stress transcriptional regulator 1014793 oxyR 4547250 oxyR Francisella tularensis subsp. novicida U112 oxidative stress transcriptional regulator YP_898601.1 1013924 D 401614 CDS YP_898602.1 118497552 4547251 complement(1014796..1015527) 1 NC_008601.1 hypothetical protein 1015527 4547251 FTN_0960 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898602.1 1014796 R 401614 CDS YP_898603.1 118497553 4547252 complement(1015541..1015813) 1 NC_008601.1 hypothetical protein 1015813 4547252 FTN_0961 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898603.1 1015541 R 401614 CDS YP_898604.1 118497554 4547253 complement(1015897..1016691) 1 NC_008601.1 hypothetical protein 1016691 4547253 FTN_0962 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898604.1 1015897 R 401614 CDS YP_898605.1 118497555 4547254 complement(1016696..1018192) 1 NC_008601.1 NAD-dependent aldehyde dehydrogenase 1018192 4547254 FTN_0963 Francisella tularensis subsp. novicida U112 NAD-dependent aldehyde dehydrogenase YP_898605.1 1016696 R 401614 CDS YP_898606.1 118497556 4547255 complement(1018206..1019321) 1 NC_008601.1 dehydrogenase 1019321 4547255 FTN_0964 Francisella tularensis subsp. novicida U112 dehydrogenase YP_898606.1 1018206 R 401614 CDS YP_898607.1 118497557 4547256 1019741..1021150 1 NC_008601.1 metal-dependent exopeptidase 1021150 4547256 FTN_0965 Francisella tularensis subsp. novicida U112 metal-dependent exopeptidase YP_898607.1 1019741 D 401614 CDS YP_898608.1 118497558 4547257 complement(1021587..1022996) 1 NC_008601.1 hypothetical protein 1022996 4547257 FTN_0966 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898608.1 1021587 R 401614 CDS YP_898609.1 118497559 4547258 complement(1022983..1023456) 1 NC_008601.1 D-alanyl-D-alanine carboxypeptidase 1023456 vanY 4547258 vanY Francisella tularensis subsp. novicida U112 D-alanyl-D-alanine carboxypeptidase YP_898609.1 1022983 R 401614 CDS YP_898610.1 118497560 4547259 complement(1023450..1024142) 1 NC_008601.1 DNA polymerase III subunit epsilon 1024142 dnaQ 4547259 dnaQ Francisella tularensis subsp. novicida U112 DNA polymerase III subunit epsilon YP_898610.1 1023450 R 401614 CDS YP_898611.1 118497561 4547260 complement(1024196..1025695) 1 NC_008601.1 hypothetical protein 1025695 4547260 FTN_0969 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898611.1 1024196 R 401614 CDS YP_898612.1 118497562 4547261 complement(1025699..1025914) 1 NC_008601.1 hypothetical protein 1025914 4547261 FTN_0970 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898612.1 1025699 R 401614 CDS YP_898613.1 118497563 4547262 complement(1025920..1026252) 1 NC_008601.1 phosphonoacetate hydrolase 1026252 phnA 4547262 phnA Francisella tularensis subsp. novicida U112 phosphonoacetate hydrolase YP_898613.1 1025920 R 401614 CDS YP_898614.1 118497564 4547397 complement(1026358..1027734) 1 NC_008601.1 hypothetical protein 1027734 4547397 FTN_0972 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898614.1 1026358 R 401614 CDS YP_898615.1 118497565 4547398 complement(1027799..1028398) 1 NC_008601.1 AhpC/TSA family peroxiredoxin 1028398 4547398 FTN_0973 Francisella tularensis subsp. novicida U112 AhpC/TSA family peroxiredoxin YP_898615.1 1027799 R 401614 CDS YP_898616.1 118497566 4547399 1028537..1029118 1 NC_008601.1 haloacid dehalogenase-like hydrolase 1029118 4547399 FTN_0974 Francisella tularensis subsp. novicida U112 haloacid dehalogenase-like hydrolase YP_898616.1 1028537 D 401614 CDS YP_898617.1 118497567 4547400 1029173..1030663 1 NC_008601.1 hypothetical protein 1030663 4547400 FTN_0975 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898617.1 1029173 D 401614 CDS YP_898618.1 118497568 4547401 1030667..1031410 1 NC_008601.1 ThiF family protein 1031410 4547401 FTN_0976 Francisella tularensis subsp. novicida U112 ThiF family protein YP_898618.1 1030667 D 401614 CDS YP_898619.1 118497569 4547402 1031487..1032056 1 NC_008601.1 hypothetical protein 1032056 4547402 FTN_0977 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898619.1 1031487 D 401614 CDS YP_898620.1 118497570 4547403 complement(1032065..1032700) 1 NC_008601.1 ubiquinone biosynthesis protein 1032700 4547403 FTN_0978 Francisella tularensis subsp. novicida U112 ubiquinone biosynthesis protein YP_898620.1 1032065 R 401614 CDS YP_898621.1 118497571 4547404 complement(1032716..1033228) 1 NC_008601.1 major facilitator transporter 1033228 4547404 FTN_0979 Francisella tularensis subsp. novicida U112 major facilitator transporter YP_898621.1 1032716 R 401614 CDS YP_898622.1 118497572 4547405 1033379..1034338 1 NC_008601.1 Catalyzes the reversible oxidation of malate to oxaloacetate; malate dehydrogenase 1034338 mdh 4547405 mdh Francisella tularensis subsp. novicida U112 malate dehydrogenase YP_898622.1 1033379 D 401614 CDS YP_898623.1 118497573 4547406 1034542..1036314 1 NC_008601.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1036314 nrdA 4547406 nrdA Francisella tularensis subsp. novicida U112 ribonucleotide-diphosphate reductase subunit alpha YP_898623.1 1034542 D 401614 CDS YP_898624.1 118497574 4547407 1036318..1036578 1 NC_008601.1 glutaredoxin 1036578 grxA 4547407 grxA Francisella tularensis subsp. novicida U112 glutaredoxin YP_898624.1 1036318 D 401614 CDS YP_898625.1 118497575 4547408 1036585..1037817 1 NC_008601.1 bifunctional gluaredoxin/ribonucleoside-diphosphate reductase subunit beta 1037817 4547408 FTN_0983 Francisella tularensis subsp. novicida U112 bifunctional gluaredoxin/ribonucleoside-diphosphate reductase subunit beta YP_898625.1 1036585 D 401614 CDS YP_898626.1 118497576 4547409 complement(1037814..1039706) 1 NC_008601.1 ABC transporter ATP-binding protein 1039706 4547409 FTN_0984 Francisella tularensis subsp. novicida U112 ABC transporter ATP-binding protein YP_898626.1 1037814 R 401614 CDS YP_898627.1 118497577 4547410 1039817..1040419 1 NC_008601.1 DJ-1/PfpI family protein 1040419 4547410 FTN_0985 Francisella tularensis subsp. novicida U112 DJ-1/PfpI family protein YP_898627.1 1039817 D 401614 CDS YP_898628.1 118497578 4547411 1040426..1041475 1 NC_008601.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 1041475 dinP 4547411 dinP Francisella tularensis subsp. novicida U112 DNA polymerase IV YP_898628.1 1040426 D 401614 CDS YP_898629.1 118497579 4547412 complement(1042429..1043415) 1 NC_008601.1 tRNA-dihydrouridine synthase 1043415 4547412 FTN_0987 Francisella tularensis subsp. novicida U112 tRNA-dihydrouridine synthase YP_898629.1 1042429 R 401614 CDS YP_898630.1 118497580 4547413 complement(1043405..1044250) 1 NC_008601.1 50S ribosomal protein L11 methyltransferase 1044250 prmA 4547413 prmA Francisella tularensis subsp. novicida U112 50S ribosomal protein L11 methyltransferase YP_898630.1 1043405 R 401614 CDS YP_898631.1 118497581 4547414 complement(1044412..1045569) 1 NC_008601.1 Fe-dependent alcohol dehydrogenase 1045569 yqhD 4547414 yqhD Francisella tularensis subsp. novicida U112 Fe-dependent alcohol dehydrogenase YP_898631.1 1044412 R 401614 CDS YP_898632.1 118497582 4547415 complement(1045584..1048394) 1 NC_008601.1 4Fe-4S ferredoxin 1048394 4547415 FTN_0990 Francisella tularensis subsp. novicida U112 4Fe-4S ferredoxin YP_898632.1 1045584 R 401614 CDS YP_898633.1 118497583 4547416 complement(1048713..1049855) 1 NC_008601.1 L-lactate dehydrogenase 1049855 lldD 4547416 lldD Francisella tularensis subsp. novicida U112 L-lactate dehydrogenase YP_898633.1 1048713 R 401614 CDS YP_898634.1 118497584 4548206 complement(1050287..1051477) 1 NC_008601.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 1051477 tyrS 4548206 tyrS Francisella tularensis subsp. novicida U112 tyrosyl-tRNA synthetase YP_898634.1 1050287 R 401614 CDS YP_898635.1 118497585 4548207 1051591..1052493 1 NC_008601.1 lipoate-protein ligase A 1052493 lplA 4548207 lplA Francisella tularensis subsp. novicida U112 lipoate-protein ligase A YP_898635.1 1051591 D 401614 CDS YP_898636.1 118497586 4548208 complement(1052496..1053245) 1 NC_008601.1 hypothetical protein 1053245 4548208 FTN_0994 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898636.1 1052496 R 401614 CDS YP_898637.1 118497587 4548209 1053437..1053988 1 NC_008601.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 1053988 hslV 4548209 hslV Francisella tularensis subsp. novicida U112 ATP-dependent protease peptidase subunit YP_898637.1 1053437 D 401614 CDS YP_898638.1 118497588 4548210 1053996..1055363 1 NC_008601.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 1055363 hslU 4548210 hslU Francisella tularensis subsp. novicida U112 ATP-dependent protease ATP-binding subunit HslU YP_898638.1 1053996 D 401614 CDS YP_898639.1 118497589 4548211 1056320..1057771 1 NC_008601.1 proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter 1057771 4548211 FTN_0997 Francisella tularensis subsp. novicida U112 proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter YP_898639.1 1056320 D 401614 CDS YP_898640.1 118497590 4548212 1057851..1059011 1 NC_008601.1 potassium channel protein 1059011 4548212 FTN_0998 Francisella tularensis subsp. novicida U112 potassium channel protein YP_898640.1 1057851 D 401614 CDS YP_898641.1 118497591 4548213 1059107..1060507 1 NC_008601.1 catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase 1060507 udhA 4548213 udhA Francisella tularensis subsp. novicida U112 soluble pyridine nucleotide transhydrogenase YP_898641.1 1059107 D 401614 CDS YP_898642.1 118497592 4548214 1060511..1061359 1 NC_008601.1 Type IV pili leader peptidase and methylase 1061359 pilD 4548214 pilD Francisella tularensis subsp. novicida U112 Type IV pili leader peptidase and methylase YP_898642.1 1060511 D 401614 CDS YP_898643.1 118497593 4548215 1061369..1062214 1 NC_008601.1 hypothetical protein 1062214 4548215 FTN_1001 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898643.1 1061369 D 401614 CDS YP_898644.1 118497594 4548216 1062223..1063107 1 NC_008601.1 beta-lactamase class A 1063107 blaA 4548216 blaA Francisella tularensis subsp. novicida U112 beta-lactamase class A YP_898644.1 1062223 D 401614 CDS YP_898645.1 118497595 4548217 1063100..1063675 1 NC_008601.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1063675 pth 4548217 pth Francisella tularensis subsp. novicida U112 peptidyl-tRNA hydrolase YP_898645.1 1063100 D 401614 CDS YP_898646.1 118497596 4548218 1063694..1064785 1 NC_008601.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 1064785 ychF 4548218 ychF Francisella tularensis subsp. novicida U112 GTP-dependent nucleic acid-binding protein EngD YP_898646.1 1063694 D 401614 CDS YP_898647.1 118497597 4548219 1064800..1065078 1 NC_008601.1 hypothetical protein 1065078 4548219 FTN_1005 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898647.1 1064800 D 401614 CDS YP_898648.1 118497598 4548220 complement(1065115..1066374) 1 NC_008601.1 HlyC/CorC family transporter-associated protein 1066374 4548220 FTN_1006 Francisella tularensis subsp. novicida U112 HlyC/CorC family transporter-associated protein YP_898648.1 1065115 R 401614 CDS YP_898649.1 118497599 4548221 complement(1066470..1066760) 1 NC_008601.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 1066760 rplY 4548221 rplY Francisella tularensis subsp. novicida U112 50S ribosomal protein L25 YP_898649.1 1066470 R 401614 CDS YP_898650.1 118497600 4548222 complement(1066860..1067828) 1 NC_008601.1 ribose-phosphate pyrophosphokinase 1067828 prsA 4548222 prsA Francisella tularensis subsp. novicida U112 ribose-phosphate pyrophosphokinase YP_898650.1 1066860 R 401614 CDS YP_898651.1 118497601 4548223 1068039..1069046 1 NC_008601.1 hypothetical protein 1069046 4548223 FTN_1009 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898651.1 1068039 D 401614 CDS YP_898652.1 118497602 4548292 1069039..1070322 1 NC_008601.1 major facilitator transporter 1070322 4548292 FTN_1010 Francisella tularensis subsp. novicida U112 major facilitator transporter YP_898652.1 1069039 D 401614 CDS YP_898653.1 118497603 4548293 complement(1070329..1071615) 1 NC_008601.1 major facilitator superfamily sugar transporter 1071615 4548293 FTN_1011 Francisella tularensis subsp. novicida U112 major facilitator superfamily sugar transporter YP_898653.1 1070329 R 401614 CDS YP_898654.1 118497604 4548294 1071927..1072760 1 NC_008601.1 small conductance mechanosensitive ion channel family protein 1072760 4548294 FTN_1012 Francisella tularensis subsp. novicida U112 small conductance mechanosensitive ion channel family protein YP_898654.1 1071927 D 401614 CDS YP_898655.1 118497605 4548295 complement(1072738..1073913) 1 NC_008601.1 monovalent cation:proton antiporter family protein 1073913 4548295 FTN_1013 Francisella tularensis subsp. novicida U112 monovalent cation:proton antiporter family protein YP_898655.1 1072738 R 401614 CDS YP_898656.1 118497606 4548296 complement(1074011..1074643) 1 NC_008601.1 nicotinamide ribonucleoside (NR) uptake permease (PnuC) family protein 1074643 4548296 FTN_1014 Francisella tularensis subsp. novicida U112 nicotinamide ribonucleoside (NR) uptake permease (PnuC) family protein YP_898656.1 1074011 R 401614 CDS YP_898657.1 118497607 4548297 complement(1074643..1075146) 1 NC_008601.1 isochorismatase family protein 1075146 4548297 FTN_1015 Francisella tularensis subsp. novicida U112 isochorismatase family protein YP_898657.1 1074643 R 401614 CDS YP_898658.1 118497608 4548298 complement(1075253..1075756) 1 NC_008601.1 hypothetical protein 1075756 4548298 FTN_1016 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898658.1 1075253 R 401614 CDS YP_898659.1 118497609 4548300 1076556..1077254 1 NC_008601.1 aldolase/adducin class II family protein 1077254 4548300 FTN_1018 Francisella tularensis subsp. novicida U112 aldolase/adducin class II family protein YP_898659.1 1076556 D 401614 CDS YP_898660.1 118497610 4548301 1077269..1078405 1 NC_008601.1 catalyzes the formation of histamine from L-histidine; histidine decarboxylase 1078405 hdc 4548301 hdc Francisella tularensis subsp. novicida U112 histidine decarboxylase YP_898660.1 1077269 D 401614 CDS YP_898661.1 118497611 4548302 complement(1078392..1079204) 1 NC_008601.1 hypothetical protein 1079204 4548302 FTN_1020 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898661.1 1078392 R 401614 CDS YP_898662.1 118497612 4548303 1079294..1079830 1 NC_008601.1 hypothetical protein 1079830 4548303 FTN_1021 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898662.1 1079294 D 401614 CDS YP_898663.1 118497613 4548304 1079866..1080162 1 NC_008601.1 hypothetical protein 1080162 4548304 FTN_1022 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898663.1 1079866 D 401614 CDS YP_898664.1 118497614 4548305 complement(1080184..1080771) 1 NC_008601.1 hypothetical protein 1080771 4548305 FTN_1023 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898664.1 1080184 R 401614 CDS YP_898665.1 118497615 4548306 complement(1080820..1082235) 1 NC_008601.1 RmuC family protein 1082235 4548306 FTN_1024 Francisella tularensis subsp. novicida U112 RmuC family protein YP_898665.1 1080820 R 401614 CDS YP_898666.1 118497616 4548307 complement(1082261..1082911) 1 NC_008601.1 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 1082911 ruvA 4548307 ruvA Francisella tularensis subsp. novicida U112 Holliday junction DNA helicase RuvA YP_898666.1 1082261 R 401614 CDS YP_898667.1 118497617 4548308 complement(1082924..1084117) 1 NC_008601.1 major facilitator superfamily sugar transporter 1084117 4548308 FTN_1026 Francisella tularensis subsp. novicida U112 major facilitator superfamily sugar transporter YP_898667.1 1082924 R 401614 CDS YP_898668.1 118497618 4548309 complement(1084199..1084714) 1 NC_008601.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 1084714 ruvC 4548309 ruvC Francisella tularensis subsp. novicida U112 Holliday junction resolvase YP_898668.1 1084199 R 401614 CDS YP_898669.1 118497619 4548310 complement(1084811..1085557) 1 NC_008601.1 hypothetical protein 1085557 4548310 FTN_1028 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898669.1 1084811 R 401614 CDS YP_898670.1 118497620 4548311 complement(1085573..1086232) 1 NC_008601.1 isoprenoid biosynthesis protein with amidotransferase-like domain 1086232 4548311 FTN_1029 Francisella tularensis subsp. novicida U112 isoprenoid biosynthesis protein with amidotransferase-like domain YP_898670.1 1085573 R 401614 CDS YP_898671.1 118497621 4547962 complement(1086262..1087245) 1 NC_008601.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 1087245 lipA 4547962 lipA Francisella tularensis subsp. novicida U112 lipoyl synthase YP_898671.1 1086262 R 401614 CDS YP_898672.1 118497622 4547963 1087455..1087955 1 NC_008601.1 ferric iron binding protein, ferritin-like 1087955 ftnA 4547963 ftnA Francisella tularensis subsp. novicida U112 ferric iron binding protein, ferritin-like YP_898672.1 1087455 D 401614 CDS YP_898673.1 118497623 4547964 complement(1087958..1089430) 1 NC_008601.1 proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter 1089430 4547964 FTN_1032 Francisella tularensis subsp. novicida U112 proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter YP_898673.1 1087958 R 401614 CDS YP_898674.1 118497624 4547965 1089601..1090245 1 NC_008601.1 cofactor involved in the reduction of disulfides; glutaredoxin 1090245 grxB 4547965 grxB Francisella tularensis subsp. novicida U112 glutaredoxin YP_898674.1 1089601 D 401614 CDS YP_898675.1 118497625 4547966 1090247..1090876 1 NC_008601.1 iron-sulfur cluster-binding protein 1090876 rnfB 4547966 rnfB Francisella tularensis subsp. novicida U112 iron-sulfur cluster-binding protein YP_898675.1 1090247 D 401614 CDS YP_898676.1 118497626 4547967 1090869..1091507 1 NC_008601.1 endonuclease III 1091507 nth 4547967 nth Francisella tularensis subsp. novicida U112 endonuclease III YP_898676.1 1090869 D 401614 CDS YP_898677.1 118497627 4547968 1091504..1091935 1 NC_008601.1 hypothetical protein 1091935 4547968 FTN_1036 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898677.1 1091504 D 401614 CDS YP_898678.1 118497628 4547969 1091935..1093194 1 NC_008601.1 hypothetical protein 1093194 4547969 FTN_1037 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898678.1 1091935 D 401614 CDS YP_898679.1 118497629 4547970 1093310..1093996 1 NC_008601.1 hypothetical protein 1093996 4547970 FTN_1038 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898679.1 1093310 D 401614 CDS YP_898680.1 118497630 4547971 1094041..1097466 1 NC_008601.1 transcription-repair coupling factor 1097466 mfd 4547971 mfd Francisella tularensis subsp. novicida U112 transcription-repair coupling factor YP_898680.1 1094041 D 401614 CDS YP_898681.1 118497631 4547972 complement(1097585..1098628) 1 NC_008601.1 ketol-acid reductoisomerase 1098628 ilvC 4547972 ilvC Francisella tularensis subsp. novicida U112 ketol-acid reductoisomerase YP_898681.1 1097585 R 401614 CDS YP_898682.1 118497632 4547973 complement(1098656..1098973) 1 NC_008601.1 acetolactate synthase small subunit 1098973 ilvN 4547973 ilvN Francisella tularensis subsp. novicida U112 acetolactate synthase small subunit YP_898682.1 1098656 R 401614 CDS YP_898683.1 118497633 4547974 complement(1098978..1100675) 1 NC_008601.1 acetolactate synthase large subunit 1100675 ilvB 4547974 ilvB Francisella tularensis subsp. novicida U112 acetolactate synthase large subunit YP_898683.1 1098978 R 401614 CDS YP_898684.1 118497634 4547975 complement(1100822..1102504) 1 NC_008601.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 1102504 ilvD 4547975 ilvD Francisella tularensis subsp. novicida U112 dihydroxy-acid dehydratase YP_898684.1 1100822 R 401614 CDS YP_898685.1 118497635 4547976 complement(1102528..1104324) 1 NC_008601.1 hypothetical protein 1104324 4547976 FTN_1044 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898685.1 1102528 R 401614 CDS YP_898686.1 118497636 4547977 complement(1104467..1105060) 1 NC_008601.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 1105060 engB 4547977 engB Francisella tularensis subsp. novicida U112 ribosome biogenesis GTP-binding protein YsxC YP_898686.1 1104467 R 401614 CDS YP_898687.1 118497637 4547978 complement(1105057..1105542) 1 NC_008601.1 low molecular weight (LMW) phosphotyrosine protein phosphatase 1105542 wzb 4547978 wzb Francisella tularensis subsp. novicida U112 low molecular weight (LMW) phosphotyrosine protein phosphatase YP_898687.1 1105057 R 401614 CDS YP_898688.1 118497638 4547979 complement(1105543..1106469) 1 NC_008601.1 HflK-HflC membrane protein complex, HflC 1106469 hflC 4547979 hflC Francisella tularensis subsp. novicida U112 HflK-HflC membrane protein complex, HflC YP_898688.1 1105543 R 401614 CDS YP_898689.1 118497639 4547980 complement(1106471..1107538) 1 NC_008601.1 HflK-HflC membrane protein complex, HflK 1107538 hflK 4547980 hflK Francisella tularensis subsp. novicida U112 HflK-HflC membrane protein complex, HflK YP_898689.1 1106471 R 401614 CDS YP_898690.1 118497640 4547981 1107723..1108901 1 NC_008601.1 hypothetical protein 1108901 4547981 FTN_1049 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898690.1 1107723 D 401614 CDS YP_898691.1 118497641 4547982 complement(1108912..1110222) 1 NC_008601.1 protease, GTP-binding subunit 1110222 hflX 4547982 hflX Francisella tularensis subsp. novicida U112 protease, GTP-binding subunit YP_898691.1 1108912 R 401614 CDS YP_898692.1 118497642 4547983 complement(1110271..1110600) 1 NC_008601.1 host factor I for bacteriophage Q beta replication 1110600 hfq 4547983 hfq Francisella tularensis subsp. novicida U112 host factor I for bacteriophage Q beta replication YP_898692.1 1110271 R 401614 CDS YP_898693.1 118497643 4547984 complement(1110711..1111637) 1 NC_008601.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 1111637 miaA 4547984 miaA Francisella tularensis subsp. novicida U112 tRNA delta(2)-isopentenylpyrophosphate transferase YP_898693.1 1110711 R 401614 CDS YP_898694.1 118497644 4547985 complement(1111638..1113071) 1 NC_008601.1 hypothetical protein 1113071 4547985 FTN_1053 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898694.1 1111638 R 401614 CDS YP_898695.1 118497645 4547986 complement(1113184..1113456) 1 NC_008601.1 DNA-binding protein HU-beta 1113456 hupB 4547986 hupB Francisella tularensis subsp. novicida U112 DNA-binding protein HU-beta YP_898695.1 1113184 R 401614 CDS YP_898696.1 118497646 4547987 complement(1113543..1115867) 1 NC_008601.1 DNA-binding, ATP-dependent protease La 1115867 lon 4547987 lon Francisella tularensis subsp. novicida U112 DNA-binding, ATP-dependent protease La YP_898696.1 1113543 R 401614 CDS YP_898697.1 118497647 4547988 complement(1115892..1117145) 1 NC_008601.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1117145 clpX 4547988 clpX Francisella tularensis subsp. novicida U112 ATP-dependent protease ATP-binding subunit ClpX YP_898697.1 1115892 R 401614 CDS YP_898698.1 118497648 4547989 complement(1117169..1117774) 1 NC_008601.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 1117774 clpP 4547989 clpP Francisella tularensis subsp. novicida U112 ATP-dependent Clp protease proteolytic subunit YP_898698.1 1117169 R 401614 CDS YP_898699.1 118497649 4547990 complement(1117800..1119116) 1 NC_008601.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 1119116 tig 4547990 tig Francisella tularensis subsp. novicida U112 trigger factor YP_898699.1 1117800 R 401614 CDS YP_898700.1 118497650 4547991 1119271..1119735 1 NC_008601.1 hypothetical protein 1119735 4547991 FTN_1059 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898700.1 1119271 D 401614 CDS YP_898701.1 118497651 4547992 complement(1119778..1120371) 1 NC_008601.1 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 1120371 tdk 4547992 tdk Francisella tularensis subsp. novicida U112 thymidine kinase YP_898701.1 1119778 R 401614 CDS YP_898702.1 118497652 4547993 complement(1120387..1121136) 1 NC_008601.1 acid phosphatase 1121136 4547993 FTN_1061 Francisella tularensis subsp. novicida U112 acid phosphatase YP_898702.1 1120387 R 401614 CDS YP_898703.1 118497653 4547994 complement(1121316..1121990) 1 NC_008601.1 o-methyltransferase family protein 1121990 4547994 FTN_1062 Francisella tularensis subsp. novicida U112 o-methyltransferase family protein YP_898703.1 1121316 R 401614 CDS YP_898704.1 118497654 4547995 1122215..1123543 1 NC_008601.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 1123543 4547995 FTN_1063 Francisella tularensis subsp. novicida U112 (dimethylallyl)adenosine tRNA methylthiotransferase YP_898704.1 1122215 D 401614 CDS YP_898705.1 118497655 4547996 1123547..1124530 1 NC_008601.1 PhoH family protein ATPase 1124530 4547996 FTN_1064 Francisella tularensis subsp. novicida U112 PhoH family protein ATPase YP_898705.1 1123547 D 401614 CDS YP_898706.1 118497656 4547997 1124523..1125011 1 NC_008601.1 hypothetical protein 1125011 4547997 FTN_1065 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898706.1 1124523 D 401614 CDS YP_898707.1 118497657 4547998 1125001..1125843 1 NC_008601.1 HlyC/CorC family transporter-associated protein 1125843 4547998 FTN_1066 Francisella tularensis subsp. novicida U112 HlyC/CorC family transporter-associated protein YP_898707.1 1125001 D 401614 CDS YP_898708.1 118497658 4547999 1125843..1127333 1 NC_008601.1 apolipoprotein N-acyltransferase 1127333 4547999 FTN_1067 Francisella tularensis subsp. novicida U112 apolipoprotein N-acyltransferase YP_898708.1 1125843 D 401614 CDS YP_898709.1 118497659 4548000 1127581..1128003 1 NC_008601.1 hypothetical protein 1128003 4548000 FTN_1068 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898709.1 1127581 D 401614 CDS YP_898710.1 118497660 4547474 complement(1128155..1130653) 1 NC_008601.1 hypothetical protein 1130653 4547474 FTN_1069 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898710.1 1128155 R 401614 CDS YP_898711.1 118497661 4547475 complement(1130861..1132213) 1 NC_008601.1 hypothetical protein 1132213 4547475 FTN_1070 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898711.1 1130861 R 401614 CDS YP_898712.1 118497662 4547476 complement(1132421..1133899) 1 NC_008601.1 hypothetical protein 1133899 4547476 FTN_1071 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898712.1 1132421 R 401614 CDS YP_898713.1 118497663 4547477 1134341..1135204 1 NC_008601.1 beta-lactamase class A 1135204 4547477 FTN_1072 Francisella tularensis subsp. novicida U112 beta-lactamase class A YP_898713.1 1134341 D 401614 CDS YP_898714.1 118497664 4547478 complement(1135195..1136259) 1 NC_008601.1 DNA/RNA endonuclease G 1136259 4547478 FTN_1073 Francisella tularensis subsp. novicida U112 DNA/RNA endonuclease G YP_898714.1 1135195 R 401614 CDS YP_898715.1 118497665 4547479 complement(1136357..1138117) 1 NC_008601.1 X-prolyl aminopeptidase 2 1138117 4547479 FTN_1074 Francisella tularensis subsp. novicida U112 X-prolyl aminopeptidase 2 YP_898715.1 1136357 R 401614 CDS YP_898716.1 118497666 4547480 complement(1138169..1138876) 1 NC_008601.1 hypothetical protein 1138876 4547480 FTN_1075 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898716.1 1138169 R 401614 CDS YP_898717.1 118497667 4547481 complement(1138891..1140108) 1 NC_008601.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 1140108 ispG 4547481 ispG Francisella tularensis subsp. novicida U112 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_898717.1 1138891 R 401614 CDS YP_898718.1 118497668 4547482 1140193..1140939 1 NC_008601.1 hypothetical protein 1140939 4547482 FTN_1077 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898718.1 1140193 D 401614 CDS YP_898719.1 118497669 4547484 complement(1141285..1142637) 1 NC_008601.1 major facilitator superfamily sugar transporter 1142637 4547484 FTN_1079 Francisella tularensis subsp. novicida U112 major facilitator superfamily sugar transporter YP_898719.1 1141285 R 401614 CDS YP_898720.1 118497670 4547485 complement(1142671..1143699) 1 NC_008601.1 phosphosugar binding protein 1143699 4547485 FTN_1080 Francisella tularensis subsp. novicida U112 phosphosugar binding protein YP_898720.1 1142671 R 401614 CDS YP_898721.1 118497671 4547486 1143901..1145175 1 NC_008601.1 dicarboxylate/amino acid:cation (Na+ or H+) symporter 1145175 4547486 FTN_1081 Francisella tularensis subsp. novicida U112 dicarboxylate/amino acid:cation (Na+ or H+) symporter YP_898721.1 1143901 D 401614 CDS YP_898722.1 118497672 4547487 complement(1145207..1146601) 1 NC_008601.1 hypothetical protein 1146601 4547487 FTN_1082 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898722.1 1145207 R 401614 CDS YP_898723.1 118497673 4547488 1146713..1147330 1 NC_008601.1 hypothetical protein 1147330 4547488 FTN_1083 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898723.1 1146713 D 401614 CDS YP_898724.1 118497674 4547489 1147417..1147587 1 NC_008601.1 rubredoxin 1147587 rubA 4547489 rubA Francisella tularensis subsp. novicida U112 rubredoxin YP_898724.1 1147417 D 401614 CDS YP_898725.1 118497675 4547490 1147596..1148468 1 NC_008601.1 hypothetical protein 1148468 4547490 FTN_1085 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898725.1 1147596 D 401614 CDS YP_898726.1 118497676 4547491 1148532..1149137 1 NC_008601.1 hypothetical protein 1149137 4547491 FTN_1086 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898726.1 1148532 D 401614 CDS YP_898727.1 118497677 4547492 complement(1149424..1150110) 1 NC_008601.1 carbonic anhydrase 1150110 cynT 4547492 cynT Francisella tularensis subsp. novicida U112 carbonic anhydrase YP_898727.1 1149424 R 401614 CDS YP_898728.1 118497678 4548648 complement(1150181..1151218) 1 NC_008601.1 L-asparaginase 1151218 ansA 4548648 ansA Francisella tularensis subsp. novicida U112 L-asparaginase YP_898728.1 1150181 R 401614 CDS YP_898729.1 118497679 4548649 complement(1151220..1151678) 1 NC_008601.1 ribonuclease H 1151678 rnhA 4548649 rnhA Francisella tularensis subsp. novicida U112 ribonuclease H YP_898729.1 1151220 R 401614 CDS YP_898730.1 118497680 4548650 complement(1151653..1152243) 1 NC_008601.1 hypothetical protein 1152243 4548650 FTN_1090 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898730.1 1151653 R 401614 CDS YP_898731.1 118497681 4548651 complement(1152246..1153523) 1 NC_008601.1 3-phosphoshikimate 1-carboxyvinyltransferase 1153523 aroA 4548651 aroA Francisella tularensis subsp. novicida U112 3-phosphoshikimate 1-carboxyvinyltransferase YP_898731.1 1152246 R 401614 CDS YP_898732.1 118497682 4548652 complement(1153614..1154492) 1 NC_008601.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 1154492 rpoH 4548652 rpoH Francisella tularensis subsp. novicida U112 RNA polymerase factor sigma-32 YP_898732.1 1153614 R 401614 CDS YP_898733.1 118497683 4548653 complement(1154516..1155004) 1 NC_008601.1 hypothetical protein 1155004 4548653 FTN_1093 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898733.1 1154516 R 401614 CDS YP_898734.1 118497684 4548654 complement(1155078..1156022) 1 NC_008601.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 1156022 secF 4548654 secF Francisella tularensis subsp. novicida U112 preprotein translocase subunit SecF YP_898734.1 1155078 R 401614 CDS YP_898735.1 118497685 4548655 complement(1156041..1157978) 1 NC_008601.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 1157978 secD 4548655 secD Francisella tularensis subsp. novicida U112 preprotein translocase subunit SecD YP_898735.1 1156041 R 401614 CDS YP_898736.1 118497686 4548656 complement(1158035..1158391) 1 NC_008601.1 preprotein translocase family protein 1158391 yajC 4548656 yajC Francisella tularensis subsp. novicida U112 preprotein translocase family protein YP_898736.1 1158035 R 401614 CDS YP_898737.1 118497687 4548657 complement(1158943..1159515) 1 NC_008601.1 isochorismatase hydrolase family protein 1159515 4548657 FTN_1097 Francisella tularensis subsp. novicida U112 isochorismatase hydrolase family protein YP_898737.1 1158943 R 401614 CDS YP_898738.1 118497688 4548658 complement(1159527..1160402) 1 NC_008601.1 hypothetical protein 1160402 4548658 FTN_1098 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898738.1 1159527 R 401614 CDS YP_898739.1 118497689 4548659 1160507..1161382 1 NC_008601.1 LysR family transcriptional regulator 1161382 4548659 FTN_1099 Francisella tularensis subsp. novicida U112 LysR family transcriptional regulator YP_898739.1 1160507 D 401614 CDS YP_898740.1 118497690 4548660 complement(1161389..1162492) 1 NC_008601.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 1162492 tgt 4548660 tgt Francisella tularensis subsp. novicida U112 queuine tRNA-ribosyltransferase YP_898740.1 1161389 R 401614 CDS YP_898741.1 118497691 4548661 complement(1162957..1163790) 1 NC_008601.1 hypothetical protein 1163790 4548661 FTN_1101 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898741.1 1162957 R 401614 CDS YP_898742.1 118497692 4548662 1164373..1164603 1 NC_008601.1 hypothetical protein 1164603 4548662 FTN_1102 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898742.1 1164373 D 401614 CDS YP_898743.1 118497693 4548663 complement(1164644..1165492) 1 NC_008601.1 hypothetical protein 1165492 4548663 FTN_1103 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898743.1 1164644 R 401614 CDS YP_898744.1 118497694 4548664 complement(1165519..1166067) 1 NC_008601.1 hypothetical protein 1166067 4548664 FTN_1104 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898744.1 1165519 R 401614 CDS YP_898745.1 118497695 4548665 1166699..1167313 1 NC_008601.1 hypothetical protein 1167313 4548665 FTN_1105 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898745.1 1166699 D 401614 CDS YP_898746.1 118497696 4548666 1167276..1168352 1 NC_008601.1 methionine uptake transporter (MUT) family protein 1168352 metN 4548666 metN Francisella tularensis subsp. novicida U112 methionine uptake transporter (MUT) family protein YP_898746.1 1167276 D 401614 CDS YP_898747.1 118497697 4548667 1168330..1169802 1 NC_008601.1 methionine uptake transporter (MUT) family protein, membrane and periplasmic protein 1169802 metlQ 4548667 metlQ Francisella tularensis subsp. novicida U112 methionine uptake transporter (MUT) family protein, membrane and periplasmic protein YP_898747.1 1168330 D 401614 CDS YP_898748.1 118497698 4547889 1169873..1171084 1 NC_008601.1 hydroxy/aromatic amino acid permease (HAAAP) family protein 1171084 4547889 FTN_1108 Francisella tularensis subsp. novicida U112 hydroxy/aromatic amino acid permease (HAAAP) family protein YP_898748.1 1169873 D 401614 CDS YP_898749.1 118497699 4547890 1171158..1171907 1 NC_008601.1 rhodanese-like family protein 1171907 4547890 FTN_1109 Francisella tularensis subsp. novicida U112 rhodanese-like family protein YP_898749.1 1171158 D 401614 CDS YP_898750.1 118497700 4547891 1171920..1172399 1 NC_008601.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 1172399 ispF 4547891 ispF Francisella tularensis subsp. novicida U112 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_898750.1 1171920 D 401614 CDS YP_898751.1 118497701 4547892 complement(1172404..1174089) 1 NC_008601.1 Mur ligase family protein 1174089 4547892 FTN_1111 Francisella tularensis subsp. novicida U112 Mur ligase family protein YP_898751.1 1172404 R 401614 CDS YP_898752.1 118497702 4547893 complement(1174115..1176937) 1 NC_008601.1 catalyze the formation of cyanophycin which may act to store excess nitrogen; cyanophycin synthetase 1176937 cphA 4547893 cphA Francisella tularensis subsp. novicida U112 cyanophycin synthetase YP_898752.1 1174115 R 401614 CDS YP_898753.1 118497703 4547894 1177061..1177804 1 NC_008601.1 hypothetical protein 1177804 4547894 FTN_1113 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898753.1 1177061 D 401614 CDS YP_898754.1 118497704 4547895 complement(1177793..1178545) 1 NC_008601.1 glycerophosphoryl diester phosphodiesterase 1178545 glpQ 4547895 glpQ Francisella tularensis subsp. novicida U112 glycerophosphoryl diester phosphodiesterase YP_898754.1 1177793 R 401614 CDS YP_898755.1 118497705 4547896 1178703..1180481 1 NC_008601.1 Type IV pili ATPase 1180481 pilB 4547896 pilB Francisella tularensis subsp. novicida U112 Type IV pili ATPase YP_898755.1 1178703 D 401614 CDS YP_898756.1 118497706 4547897 1180496..1181725 1 NC_008601.1 Type IV pili polytopic inner membrane protein 1181725 pilC 4547897 pilC Francisella tularensis subsp. novicida U112 Type IV pili polytopic inner membrane protein YP_898756.1 1180496 D 401614 CDS YP_898757.1 118497707 4547898 complement(1181799..1182965) 1 NC_008601.1 ATP-binding protein 1182965 4547898 FTN_1117 Francisella tularensis subsp. novicida U112 ATP-binding protein YP_898757.1 1181799 R 401614 CDS YP_898758.1 118497708 4547899 complement(1182983..1183318) 1 NC_008601.1 hypothetical protein 1183318 4547899 FTN_1118 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898758.1 1182983 R 401614 CDS YP_898759.1 118497709 4547900 complement(1183335..1183586) 1 NC_008601.1 hypothetical protein 1183586 4547900 FTN_1119 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898759.1 1183335 R 401614 CDS YP_898760.1 118497710 4547901 1183729..1184730 1 NC_008601.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 1184730 hemH 4547901 hemH Francisella tularensis subsp. novicida U112 ferrochelatase YP_898760.1 1183729 D 401614 CDS YP_898761.1 118497711 4547902 1184715..1186109 1 NC_008601.1 deoxyribodipyrimidine photolyase 1186109 phrB 4547902 phrB Francisella tularensis subsp. novicida U112 deoxyribodipyrimidine photolyase YP_898761.1 1184715 D 401614 CDS YP_898762.1 118497712 4547903 1186844..1187233 1 NC_008601.1 hypothetical protein 1187233 4547903 FTN_1122 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898762.1 1186844 D 401614 CDS YP_898763.1 118497713 4547904 1187288..1187593 1 NC_008601.1 hypothetical protein 1187593 4547904 FTN_1123 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898763.1 1187288 D 401614 CDS YP_898764.1 118497714 4547905 1187659..1187904 1 NC_008601.1 hypothetical protein 1187904 4547905 FTN_1124 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898764.1 1187659 D 401614 CDS YP_898765.1 118497715 4547906 1188089..1188952 1 NC_008601.1 short chain dehydrogenase 1188952 4547906 FTN_1125 Francisella tularensis subsp. novicida U112 short chain dehydrogenase YP_898765.1 1188089 D 401614 CDS YP_898766.1 118497716 4547907 1188964..1189194 1 NC_008601.1 cation transport regulator 1189194 chaB 4547907 chaB Francisella tularensis subsp. novicida U112 cation transport regulator YP_898766.1 1188964 D 401614 CDS YP_898767.1 118497717 4548705 complement(1189304..1190299) 1 NC_008601.1 aldose 1-epimerase 1190299 galM 4548705 galM Francisella tularensis subsp. novicida U112 aldose 1-epimerase YP_898767.1 1189304 R 401614 CDS YP_898768.1 118497718 4548706 complement(1190296..1191471) 1 NC_008601.1 P-pantothenate cysteine ligase/P-pantothenoylcysteine decarboxylase 1191471 dfp 4548706 dfp Francisella tularensis subsp. novicida U112 P-pantothenate cysteine ligase/P-pantothenoylcysteine decarboxylase YP_898768.1 1190296 R 401614 CDS YP_898769.1 118497719 4548707 complement(1191484..1192668) 1 NC_008601.1 major facilitator transporter 1192668 4548707 FTN_1129 Francisella tularensis subsp. novicida U112 major facilitator transporter YP_898769.1 1191484 R 401614 CDS YP_898770.1 118497720 4548708 complement(1192744..1194252) 1 NC_008601.1 amino acid transporter 1194252 4548708 FTN_1130 Francisella tularensis subsp. novicida U112 amino acid transporter YP_898770.1 1192744 R 401614 CDS YP_898771.1 118497721 4548709 complement(1194413..1198477) 1 NC_008601.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the protein from Pseudomonas does not have this domain; bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 1198477 putA 4548709 putA Francisella tularensis subsp. novicida U112 bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase YP_898771.1 1194413 R 401614 CDS YP_898772.1 118497722 4548710 complement(1198494..1198781) 1 NC_008601.1 hypothetical protein 1198781 4548710 FTN_1132 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898772.1 1198494 R 401614 CDS YP_898773.1 118497723 4548711 1198995..1199378 1 NC_008601.1 hypothetical protein 1199378 4548711 FTN_1133 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898773.1 1198995 D 401614 CDS YP_898774.1 118497724 4548712 complement(1199445..1199690) 1 NC_008601.1 hypothetical protein 1199690 4548712 FTN_1134 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898774.1 1199445 R 401614 CDS YP_898775.1 118497725 4548713 complement(1199726..1200805) 1 NC_008601.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 1200805 aroB 4548713 aroB Francisella tularensis subsp. novicida U112 3-dehydroquinate synthase YP_898775.1 1199726 R 401614 CDS YP_898776.1 118497726 4548714 complement(1200802..1201332) 1 NC_008601.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I 1201332 aroK 4548714 aroK Francisella tularensis subsp. novicida U112 shikimate kinase I YP_898776.1 1200802 R 401614 CDS YP_898777.1 118497727 4548715 complement(1201458..1203242) 1 NC_008601.1 Type IV pili secretin component 1203242 pilQ 4548715 pilQ Francisella tularensis subsp. novicida U112 Type IV pili secretin component YP_898777.1 1201458 R 401614 CDS YP_898778.1 118497728 4548716 complement(1203255..1203845) 1 NC_008601.1 Type IV pili periplasmic component 1203845 pilP 4548716 pilP Francisella tularensis subsp. novicida U112 Type IV pili periplasmic component YP_898778.1 1203255 R 401614 CDS YP_898779.1 118497729 4548717 complement(1203851..1204447) 1 NC_008601.1 Type IV pili glycosylation protein 1204447 pilO 4548717 pilO Francisella tularensis subsp. novicida U112 Type IV pili glycosylation protein YP_898779.1 1203851 R 401614 CDS YP_898780.1 118497730 4548718 complement(1204441..1205004) 1 NC_008601.1 Type IV pili associated protein 1205004 pilN 4548718 pilN Francisella tularensis subsp. novicida U112 Type IV pili associated protein YP_898780.1 1204441 R 401614 CDS YP_898781.1 118497731 4548719 complement(1205006..1206010) 1 NC_008601.1 hypothetical protein 1206010 pilM 4548719 pilM Francisella tularensis subsp. novicida U112 hypothetical protein YP_898781.1 1205006 R 401614 CDS YP_898782.1 118497732 4548720 1206137..1206793 1 NC_008601.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 1206793 adk 4548720 adk Francisella tularensis subsp. novicida U112 adenylate kinase YP_898782.1 1206137 D 401614 CDS YP_898783.1 118497733 4548721 complement(1207352..1210072) 1 NC_008601.1 4Fe-4S ferredoxin 1210072 4548721 FTN_1143 Francisella tularensis subsp. novicida U112 4Fe-4S ferredoxin YP_898783.1 1207352 R 401614 CDS YP_898784.1 118497734 4548722 complement(1210133..1210549) 1 NC_008601.1 hypothetical protein 1210549 4548722 FTN_1144 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898784.1 1210133 R 401614 CDS YP_898785.1 118497735 4548723 complement(1210564..1211457) 1 NC_008601.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 1211457 era 4548723 era Francisella tularensis subsp. novicida U112 GTP-binding protein Era YP_898785.1 1210564 R 401614 CDS YP_898786.1 118497736 4548724 complement(1211571..1212764) 1 NC_008601.1 aspartate aminotransferase 1212764 4548724 FTN_1146 Francisella tularensis subsp. novicida U112 aspartate aminotransferase YP_898786.1 1211571 R 401614 CDS YP_898787.1 118497737 4548133 complement(1212774..1213580) 1 NC_008601.1 glutamine amidotransferases class-II family protein 1213580 4548133 FTN_1147 Francisella tularensis subsp. novicida U112 glutamine amidotransferases class-II family protein YP_898787.1 1212774 R 401614 CDS YP_898788.1 118497738 4548134 complement(1213584..1214222) 1 NC_008601.1 glycoprotease family protein 1214222 4548134 FTN_1148 Francisella tularensis subsp. novicida U112 glycoprotease family protein YP_898788.1 1213584 R 401614 CDS YP_898789.1 118497739 4548135 complement(1214226..1215359) 1 NC_008601.1 N-acetylglucosamine-6-phosphate deacetylase 1215359 nagA 4548135 nagA Francisella tularensis subsp. novicida U112 N-acetylglucosamine-6-phosphate deacetylase YP_898789.1 1214226 R 401614 CDS YP_898790.1 118497740 4548136 1215422..1216294 1 NC_008601.1 GTP-binding protein 1216294 4548136 FTN_1150 Francisella tularensis subsp. novicida U112 GTP-binding protein YP_898790.1 1215422 D 401614 CDS YP_898791.1 118497741 4548137 1216361..1218109 1 NC_008601.1 hypothetical protein 1218109 4548137 FTN_1151 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898791.1 1216361 D 401614 CDS YP_898792.1 118497742 4548138 complement(1218099..1219547) 1 NC_008601.1 type I restriction-modification system subunit M (methyltransferase) 1219547 4548138 FTN_1152 Francisella tularensis subsp. novicida U112 type I restriction-modification system subunit M (methyltransferase) YP_898792.1 1218099 R 401614 CDS YP_898793.1 118497743 4548139 complement(1219528..1220226) 1 NC_008601.1 hypothetical protein 1220226 4548139 FTN_1153 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898793.1 1219528 R 401614 CDS YP_898794.1 118497744 4548140 complement(1220793..1222016) 1 NC_008601.1 type I restriction-modification system subunit S 1222016 4548140 FTN_1154 Francisella tularensis subsp. novicida U112 type I restriction-modification system subunit S YP_898794.1 1220793 R 401614 CDS YP_898795.1 118497745 4548141 complement(1222621..1224969) 1 NC_008601.1 type I restriction-modification system subunit R (restriction) 1224969 4548141 FTN_1155 Francisella tularensis subsp. novicida U112 type I restriction-modification system subunit R (restriction) YP_898795.1 1222621 R 401614 CDS YP_898796.1 118497746 4548142 complement(1225102..1226655) 1 NC_008601.1 hypothetical protein 1226655 4548142 FTN_1156 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898796.1 1225102 R 401614 CDS YP_898797.1 118497747 4548143 1227077..1228894 1 NC_008601.1 GTP binding translational elongation factor Tu and G family protein 1228894 4548143 FTN_1157 Francisella tularensis subsp. novicida U112 GTP binding translational elongation factor Tu and G family protein YP_898797.1 1227077 D 401614 CDS YP_898798.1 118497748 4548144 1229066..1229821 1 NC_008601.1 methyltransferase 1229821 4548144 FTN_1158 Francisella tularensis subsp. novicida U112 methyltransferase YP_898798.1 1229066 D 401614 CDS YP_898799.1 118497749 4548145 complement(1229837..1231642) 1 NC_008601.1 gamma-glutamyltranspeptidase 1231642 ggt 4548145 ggt Francisella tularensis subsp. novicida U112 gamma-glutamyltranspeptidase YP_898799.1 1229837 R 401614 CDS YP_898800.1 118497750 4548146 complement(1231698..1232618) 1 NC_008601.1 VacJ like lipoprotein 1232618 4548146 FTN_1160 Francisella tularensis subsp. novicida U112 VacJ like lipoprotein YP_898800.1 1231698 R 401614 CDS YP_898801.1 118497751 4548147 complement(1232695..1233897) 1 NC_008601.1 hypothetical protein 1233897 4548147 FTN_1161 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898801.1 1232695 R 401614 CDS YP_898802.1 118497752 4548148 complement(1233939..1234244) 1 NC_008601.1 hypothetical protein 1234244 4548148 FTN_1162 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898802.1 1233939 R 401614 CDS YP_898803.1 118497753 4548149 complement(1234244..1234675) 1 NC_008601.1 hypothetical protein 1234675 4548149 FTN_1163 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898803.1 1234244 R 401614 CDS YP_898804.1 118497754 4548150 1234750..1235223 1 NC_008601.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 1235223 smpB 4548150 smpB Francisella tularensis subsp. novicida U112 SsrA-binding protein YP_898804.1 1234750 D 401614 CDS YP_898805.1 118497755 4548151 1235224..1235985 1 NC_008601.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 1235985 4548151 FTN_1165 Francisella tularensis subsp. novicida U112 C32 tRNA thiolase YP_898805.1 1235224 D 401614 CDS YP_898806.1 118497756 4548725 complement(1235986..1237257) 1 NC_008601.1 metabolite:H+ symporter (MHS) family protein 1237257 4548725 FTN_1166 Francisella tularensis subsp. novicida U112 metabolite:H+ symporter (MHS) family protein YP_898806.1 1235986 R 401614 CDS YP_898807.1 118497757 4548726 complement(1237355..1237555) 1 NC_008601.1 hypothetical protein 1237555 4548726 FTN_1167 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898807.1 1237355 R 401614 CDS YP_898808.1 118497758 4548727 complement(1237539..1238924) 1 NC_008601.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 1238924 xseA 4548727 xseA Francisella tularensis subsp. novicida U112 exodeoxyribonuclease VII large subunit YP_898808.1 1237539 R 401614 CDS YP_898809.1 118497759 4548728 1239077..1240237 1 NC_008601.1 M20 family peptidase 1240237 4548728 FTN_1169 Francisella tularensis subsp. novicida U112 M20 family peptidase YP_898809.1 1239077 D 401614 CDS YP_898810.1 118497760 4548729 complement(1240286..1242037) 1 NC_008601.1 hypothetical protein 1242037 4548729 FTN_1170 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898810.1 1240286 R 401614 CDS YP_898811.1 118497761 4548730 complement(1242054..1243040) 1 NC_008601.1 hypothetical protein 1243040 4548730 FTN_1171 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898811.1 1242054 R 401614 CDS YP_898812.1 118497762 4548731 complement(1243040..1244494) 1 NC_008601.1 hypothetical protein 1244494 4548731 FTN_1172 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898812.1 1243040 R 401614 CDS YP_898813.1 118497763 4548732 complement(1244655..1245932) 1 NC_008601.1 major facilitator transporter 1245932 4548732 FTN_1173 Francisella tularensis subsp. novicida U112 major facilitator transporter YP_898813.1 1244655 R 401614 CDS YP_898814.1 118497764 4548733 complement(1246023..1246820) 1 NC_008601.1 glutamate racemase 1246820 murI 4548733 murI Francisella tularensis subsp. novicida U112 glutamate racemase YP_898814.1 1246023 R 401614 CDS YP_898815.1 118497765 4548734 complement(1246820..1247617) 1 NC_008601.1 hypothetical protein 1247617 4548734 FTN_1175 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898815.1 1246820 R 401614 CDS YP_898816.1 118497766 4548735 complement(1247654..1249660) 1 NC_008601.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1249660 uvrB 4548735 uvrB Francisella tularensis subsp. novicida U112 excinuclease ABC subunit B YP_898816.1 1247654 R 401614 CDS YP_898817.1 118497767 4548736 complement(1249662..1251110) 1 NC_008601.1 exodeoxyribonuclease I 1251110 sbcB 4548736 sbcB Francisella tularensis subsp. novicida U112 exodeoxyribonuclease I YP_898817.1 1249662 R 401614 CDS YP_898818.1 118497768 4548737 complement(1251244..1251966) 1 NC_008601.1 short-chain dehydrogenase 1251966 4548737 FTN_1178 Francisella tularensis subsp. novicida U112 short-chain dehydrogenase YP_898818.1 1251244 R 401614 CDS YP_898819.1 118497769 4548738 1252082..1252981 1 NC_008601.1 LysR family transcriptional regulator 1252981 4548738 FTN_1179 Francisella tularensis subsp. novicida U112 LysR family transcriptional regulator YP_898819.1 1252082 D 401614 CDS YP_898820.1 118497770 4548739 complement(1252992..1253897) 1 NC_008601.1 hypothetical protein 1253897 4548739 FTN_1180 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898820.1 1252992 R 401614 CDS YP_898821.1 118497771 4548740 complement(1253884..1254966) 1 NC_008601.1 hypothetical protein 1254966 4548740 FTN_1181 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898821.1 1253884 R 401614 CDS YP_898822.1 118497772 4548741 1255109..1256992 1 NC_008601.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 1256992 gidA 4548741 gidA Francisella tularensis subsp. novicida U112 tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_898822.1 1255109 D 401614 CDS YP_898823.1 118497773 4548742 1257004..1257396 1 NC_008601.1 hypothetical protein 1257396 4548742 FTN_1183 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898823.1 1257004 D 401614 CDS YP_898824.1 118497774 4548743 1257410..1258780 1 NC_008601.1 hypothetical protein 1258780 4548743 FTN_1184 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898824.1 1257410 D 401614 CDS YP_898825.1 118497775 4548744 1258782..1259456 1 NC_008601.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 1259456 rpiA 4548744 rpiA Francisella tularensis subsp. novicida U112 ribose-5-phosphate isomerase A YP_898825.1 1258782 D 401614 CDS YP_898826.1 118497776 4547607 complement(1259504..1261567) 1 NC_008601.1 M13 family metallopeptidase 1261567 pepO 4547607 pepO Francisella tularensis subsp. novicida U112 M13 family metallopeptidase YP_898826.1 1259504 R 401614 CDS YP_898827.1 118497777 4547608 complement(1261656..1262360) 1 NC_008601.1 hypothetical protein 1262360 4547608 FTN_1187 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898827.1 1261656 R 401614 CDS YP_898828.1 118497778 4547609 complement(1262402..1262758) 1 NC_008601.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 1262758 rplT 4547609 rplT Francisella tularensis subsp. novicida U112 50S ribosomal protein L20 YP_898828.1 1262402 R 401614 CDS YP_898829.1 118497779 4547610 complement(1262794..1262991) 1 NC_008601.1 50S ribosomal protein L35 1262991 rpmI 4547610 rpmI Francisella tularensis subsp. novicida U112 50S ribosomal protein L35 YP_898829.1 1262794 R 401614 CDS YP_898830.1 118497780 4547611 complement(1263034..1263570) 1 NC_008601.1 translation initiation factor IF-3 1263570 infC 4547611 infC Francisella tularensis subsp. novicida U112 translation initiation factor IF-3 YP_898830.1 1263034 R 401614 CDS YP_898831.1 118497781 4547612 complement(1263577..1265481) 1 NC_008601.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 1265481 thrS 4547612 thrS Francisella tularensis subsp. novicida U112 threonyl-tRNA synthetase YP_898831.1 1263577 R 401614 CDS YP_898832.1 118497782 4547613 1265920..1267710 1 NC_008601.1 chitin-binding protein 1267710 4547613 FTN_1192 Francisella tularensis subsp. novicida U112 chitin-binding protein YP_898832.1 1265920 D 401614 CDS YP_898833.1 118497783 4547614 complement(1267795..1268091) 1 NC_008601.1 hypothetical protein 1268091 4547614 FTN_1193 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898833.1 1267795 R 401614 CDS YP_898834.1 118497784 4547615 complement(1268081..1268461) 1 NC_008601.1 glycine cleavage system protein H 1268461 gcvH1 4547615 gcvH1 Francisella tularensis subsp. novicida U112 glycine cleavage system protein H YP_898834.1 1268081 R 401614 CDS YP_898835.1 118497785 4547616 1268565..1269680 1 NC_008601.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 1269680 murG 4547616 murG Francisella tularensis subsp. novicida U112 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_898835.1 1268565 D 401614 CDS YP_898836.1 118497786 4547617 1269690..1270028 1 NC_008601.1 hypothetical protein 1270028 4547617 FTN_1196 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898836.1 1269690 D 401614 CDS YP_898837.1 118497787 4547618 1270028..1270630 1 NC_008601.1 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 1270630 recR 4547618 recR Francisella tularensis subsp. novicida U112 recombination protein RecR YP_898837.1 1270028 D 401614 CDS YP_898838.1 118497788 4547619 complement(1270638..1272752) 1 NC_008601.1 GDP diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase 1272752 spoT 4547619 spoT Francisella tularensis subsp. novicida U112 GDP diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase YP_898838.1 1270638 R 401614 CDS YP_898839.1 118497789 4547620 complement(1272821..1274032) 1 NC_008601.1 hypothetical protein 1274032 4547620 FTN_1199 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898839.1 1272821 R 401614 CDS YP_898840.1 118497790 4547621 complement(1274034..1274498) 1 NC_008601.1 capsule biosynthesis protein CapC 1274498 capC 4547621 capC Francisella tularensis subsp. novicida U112 capsule biosynthesis protein CapC YP_898840.1 1274034 R 401614 CDS YP_898841.1 118497791 4547622 complement(1274523..1275740) 1 NC_008601.1 capsule biosynthesis protein CapB 1275740 capB 4547622 capB Francisella tularensis subsp. novicida U112 capsule biosynthesis protein CapB YP_898841.1 1274523 R 401614 CDS YP_898842.1 118497792 4547623 complement(1275816..1277072) 1 NC_008601.1 metabolite:H+ symporter (MHS) family protein 1277072 4547623 FTN_1202 Francisella tularensis subsp. novicida U112 metabolite:H+ symporter (MHS) family protein YP_898842.1 1275816 R 401614 CDS YP_898843.1 118497793 4547386 complement(1277743..1278606) 1 NC_008601.1 asparaginase 1278606 ans 4547386 ans Francisella tularensis subsp. novicida U112 asparaginase YP_898843.1 1277743 R 401614 CDS YP_898844.1 118497794 4547387 complement(1278821..1279639) 1 NC_008601.1 cyanophycinase 1279639 cphB 4547387 cphB Francisella tularensis subsp. novicida U112 cyanophycinase YP_898844.1 1278821 R 401614 CDS YP_898845.1 118497795 4547388 1279841..1280947 1 NC_008601.1 ribokinase 1280947 4547388 FTN_1210 Francisella tularensis subsp. novicida U112 ribokinase YP_898845.1 1279841 D 401614 CDS YP_898846.1 118497796 4547389 complement(1281238..1281900) 1 NC_008601.1 haloacid dehalogenase-like hydrolase 1281900 4547389 FTN_1211 Francisella tularensis subsp. novicida U112 haloacid dehalogenase-like hydrolase YP_898846.1 1281238 R 401614 CDS YP_898847.1 118497797 4547390 complement(1281919..1282932) 1 NC_008601.1 glycosyl transferases group 1 family protein 1282932 4547390 FTN_1212 Francisella tularensis subsp. novicida U112 glycosyl transferases group 1 family protein YP_898847.1 1281919 R 401614 CDS YP_898848.1 118497798 4547391 complement(1282935..1283942) 1 NC_008601.1 glycosyl transferase family protein 1283942 4547391 FTN_1213 Francisella tularensis subsp. novicida U112 glycosyl transferase family protein YP_898848.1 1282935 R 401614 CDS YP_898849.1 118497799 4547392 complement(1283959..1284918) 1 NC_008601.1 glycosyl transferase family protein 1284918 4547392 FTN_1214 Francisella tularensis subsp. novicida U112 glycosyl transferase family protein YP_898849.1 1283959 R 401614 CDS YP_898850.1 118497800 4547393 complement(1284952..1286112) 1 NC_008601.1 capsule polysaccharide export protein KpsC 1286112 kpsC 4547393 kpsC Francisella tularensis subsp. novicida U112 capsule polysaccharide export protein KpsC YP_898850.1 1284952 R 401614 CDS YP_898851.1 118497801 4547394 complement(1286105..1286848) 1 NC_008601.1 hypothetical protein 1286848 4547394 FTN_1216 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898851.1 1286105 R 401614 CDS YP_898852.1 118497802 4547395 complement(1286885..1288573) 1 NC_008601.1 ABC transporter ATP-binding protein 1288573 4547395 FTN_1217 Francisella tularensis subsp. novicida U112 ABC transporter ATP-binding protein YP_898852.1 1286885 R 401614 CDS YP_898853.1 118497803 4547396 complement(1288570..1289799) 1 NC_008601.1 group 1 glycosyl transferase 1289799 4547396 FTN_1218 Francisella tularensis subsp. novicida U112 group 1 glycosyl transferase YP_898853.1 1288570 R 401614 CDS YP_898854.1 118497804 4548970 complement(1289803..1290822) 1 NC_008601.1 UDP-glucose 4-epimerase 1290822 galE 4548970 galE Francisella tularensis subsp. novicida U112 UDP-glucose 4-epimerase YP_898854.1 1289803 R 401614 CDS YP_898855.1 118497805 4548971 complement(1290815..1292209) 1 NC_008601.1 lipopolysaccharide synthesis sugar transferase 1292209 4548971 FTN_1220 Francisella tularensis subsp. novicida U112 lipopolysaccharide synthesis sugar transferase YP_898855.1 1290815 R 401614 CDS YP_898856.1 118497806 4548972 complement(1292190..1292858) 1 NC_008601.1 D-ribulose-phosphate 3-epimerase 1292858 rpe 4548972 rpe Francisella tularensis subsp. novicida U112 D-ribulose-phosphate 3-epimerase YP_898856.1 1292190 R 401614 CDS YP_898857.1 118497807 4548973 1292995..1293966 1 NC_008601.1 phosphosugar isomerase 1293966 kpsF 4548973 kpsF Francisella tularensis subsp. novicida U112 phosphosugar isomerase YP_898857.1 1292995 D 401614 CDS YP_898858.1 118497808 4548974 complement(1293970..1294560) 1 NC_008601.1 hypothetical protein 1294560 4548974 FTN_1223 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898858.1 1293970 R 401614 CDS YP_898859.1 118497809 4548975 complement(1294571..1295269) 1 NC_008601.1 hypothetical protein 1295269 4548975 FTN_1224 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898859.1 1294571 R 401614 CDS YP_898860.1 118497810 4548976 complement(1295266..1296078) 1 NC_008601.1 hypothetical protein 1296078 4548976 FTN_1225 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898860.1 1295266 R 401614 CDS YP_898861.1 118497811 4548977 complement(1296075..1296404) 1 NC_008601.1 hypothetical protein 1296404 4548977 FTN_1226 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898861.1 1296075 R 401614 CDS YP_898862.1 118497812 4548978 complement(1296416..1297378) 1 NC_008601.1 metallo-beta-lactamase superfamily protein 1297378 4548978 FTN_1227 Francisella tularensis subsp. novicida U112 metallo-beta-lactamase superfamily protein YP_898862.1 1296416 R 401614 CDS YP_898863.1 118497813 4548979 complement(1297525..1298307) 1 NC_008601.1 enoyl-ACP reductase I 1298307 fabl 4548979 fabl Francisella tularensis subsp. novicida U112 enoyl-ACP reductase I YP_898863.1 1297525 R 401614 CDS YP_898864.1 118497814 4548980 1298595..1299308 1 NC_008601.1 hypothetical protein 1299308 4548980 FTN_1229 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898864.1 1298595 D 401614 CDS YP_898865.1 118497815 4548981 complement(1299556..1300131) 1 NC_008601.1 hypothetical protein 1300131 4548981 FTN_1230 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898865.1 1299556 R 401614 CDS YP_898866.1 118497816 4548982 complement(1300131..1300514) 1 NC_008601.1 lactoylglutathione lyase 1300514 gloA 4548982 gloA Francisella tularensis subsp. novicida U112 lactoylglutathione lyase YP_898866.1 1300131 R 401614 CDS YP_898867.1 118497817 4548983 1300558..1301343 1 NC_008601.1 hypothetical protein 1301343 4548983 FTN_1232 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898867.1 1300558 D 401614 CDS YP_898868.1 118497818 4548984 complement(1301595..1302386) 1 NC_008601.1 haloacid dehalogenase-like hydrolase 1302386 4548984 FTN_1233 Francisella tularensis subsp. novicida U112 haloacid dehalogenase-like hydrolase YP_898868.1 1301595 R 401614 CDS YP_898869.1 118497819 4548985 complement(1302509..1303525) 1 NC_008601.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 1303525 queA 4548985 queA Francisella tularensis subsp. novicida U112 S-adenosylmethionine--tRNA ribosyltransferase-isomerase YP_898869.1 1302509 R 401614 CDS YP_898870.1 118497820 4548986 complement(1303551..1304012) 1 NC_008601.1 hypothetical protein 1304012 4548986 FTN_1235 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898870.1 1303551 R 401614 CDS YP_898871.1 118497821 4548987 complement(1304034..1305269) 1 NC_008601.1 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 1305269 ubiF 4548987 ubiF Francisella tularensis subsp. novicida U112 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase YP_898871.1 1304034 R 401614 CDS YP_898872.1 118497822 4548988 complement(1305259..1306470) 1 NC_008601.1 2-octaprenyl-6-methoxyphenyl hydroxylase 1306470 ubiH 4548988 ubiH Francisella tularensis subsp. novicida U112 2-octaprenyl-6-methoxyphenyl hydroxylase YP_898872.1 1305259 R 401614 CDS YP_898873.1 118497823 4548989 complement(1306479..1307129) 1 NC_008601.1 hypothetical protein 1307129 4548989 FTN_1238 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898873.1 1306479 R 401614 CDS YP_898874.1 118497824 4548038 1307455..1308003 1 NC_008601.1 5-formyltetrahydrofolate cyclo-ligase 1308003 4548038 FTN_1239 Francisella tularensis subsp. novicida U112 5-formyltetrahydrofolate cyclo-ligase YP_898874.1 1307455 D 401614 CDS YP_898875.1 118497825 4548039 1308006..1308272 1 NC_008601.1 hypothetical protein 1308272 4548039 FTN_1240 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898875.1 1308006 D 401614 CDS YP_898876.1 118497826 4548040 1308279..1308905 1 NC_008601.1 DedA family protein 1308905 4548040 FTN_1241 Francisella tularensis subsp. novicida U112 DedA family protein YP_898876.1 1308279 D 401614 CDS YP_898877.1 118497827 4548041 1308961..1309608 1 NC_008601.1 DedA family protein 1309608 4548041 FTN_1242 Francisella tularensis subsp. novicida U112 DedA family protein YP_898877.1 1308961 D 401614 CDS YP_898878.1 118497828 4548042 complement(1309684..1310382) 1 NC_008601.1 RecFOR complex, RecO component 1310382 recO 4548042 recO Francisella tularensis subsp. novicida U112 RecFOR complex, RecO component YP_898878.1 1309684 R 401614 CDS YP_898879.1 118497829 4548043 complement(1310366..1310695) 1 NC_008601.1 hypothetical protein 1310695 4548043 FTN_1244 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898879.1 1310366 R 401614 CDS YP_898880.1 118497830 4548044 complement(1310688..1311863) 1 NC_008601.1 cysteine desulfarase 1311863 iscS 4548044 iscS Francisella tularensis subsp. novicida U112 cysteine desulfarase YP_898880.1 1310688 R 401614 CDS YP_898881.1 118497831 4548045 1312113..1314770 1 NC_008601.1 ribonuclease E 1314770 rne 4548045 rne Francisella tularensis subsp. novicida U112 ribonuclease E YP_898881.1 1312113 D 401614 CDS YP_898882.1 118497832 4548046 1314785..1315591 1 NC_008601.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 1315591 lgt 4548046 lgt Francisella tularensis subsp. novicida U112 prolipoprotein diacylglyceryl transferase YP_898882.1 1314785 D 401614 CDS YP_898883.1 118497833 4548047 1315576..1316400 1 NC_008601.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 1316400 thyA 4548047 thyA Francisella tularensis subsp. novicida U112 thymidylate synthase YP_898883.1 1315576 D 401614 CDS YP_898884.1 118497834 4548048 1316412..1317647 1 NC_008601.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 1317647 serA 4548048 serA Francisella tularensis subsp. novicida U112 D-3-phosphoglycerate dehydrogenase YP_898884.1 1316412 D 401614 CDS YP_898885.1 118497835 4548049 1317648..1318844 1 NC_008601.1 ATPase 1318844 4548049 FTN_1250 Francisella tularensis subsp. novicida U112 ATPase YP_898885.1 1317648 D 401614 CDS YP_898886.1 118497836 4548050 complement(1318852..1320288) 1 NC_008601.1 proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter 1320288 4548050 FTN_1251 Francisella tularensis subsp. novicida U112 proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter YP_898886.1 1318852 R 401614 CDS YP_898887.1 118497837 4548051 1320488..1321633 1 NC_008601.1 choloylglycine hydrolase family protein 1321633 4548051 FTN_1252 Francisella tularensis subsp. novicida U112 choloylglycine hydrolase family protein YP_898887.1 1320488 D 401614 CDS YP_898888.1 118497838 4548052 complement(1321634..1322698) 1 NC_008601.1 group 1 glycosyl transferase 1322698 lpcC 4548052 lpcC Francisella tularensis subsp. novicida U112 group 1 glycosyl transferase YP_898888.1 1321634 R 401614 CDS YP_898889.1 118497839 4548053 1322868..1323956 1 NC_008601.1 hypothetical protein 1323956 4548053 FTN_1254 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898889.1 1322868 D 401614 CDS YP_898890.1 118497840 4548054 1323964..1324854 1 NC_008601.1 glycosyl transferase family protein 1324854 4548054 FTN_1255 Francisella tularensis subsp. novicida U112 glycosyl transferase family protein YP_898890.1 1323964 D 401614 CDS YP_898891.1 118497841 4548055 complement(1324880..1326250) 1 NC_008601.1 hypothetical protein 1326250 4548055 FTN_1256 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898891.1 1324880 R 401614 CDS YP_898892.1 118497842 4548056 1326405..1327676 1 NC_008601.1 hypothetical protein 1327676 4548056 FTN_1257 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898892.1 1326405 D 401614 CDS YP_898893.1 118497843 4547701 complement(1327691..1328239) 1 NC_008601.1 hypothetical protein 1328239 4547701 FTN_1258 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898893.1 1327691 R 401614 CDS YP_898894.1 118497844 4547702 1328343..1329596 1 NC_008601.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 1329596 glyA 4547702 glyA Francisella tularensis subsp. novicida U112 serine hydroxymethyltransferase YP_898894.1 1328343 D 401614 CDS YP_898895.1 118497845 4547703 1329874..1331328 1 NC_008601.1 hypothetical protein 1331328 4547703 FTN_1260 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898895.1 1329874 D 401614 CDS YP_898896.1 118497846 4547704 1331640..1333127 1 NC_008601.1 hypothetical protein 1333127 4547704 FTN_1261 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898896.1 1331640 D 401614 CDS YP_898897.1 118497847 4547705 complement(1333171..1334967) 1 NC_008601.1 FAD binding family protein 1334967 mreA 4547705 mreA Francisella tularensis subsp. novicida U112 FAD binding family protein YP_898897.1 1333171 R 401614 CDS YP_898898.1 118497848 4547706 complement(1335075..1335899) 1 NC_008601.1 competence lipoprotein ComL 1335899 comL 4547706 comL Francisella tularensis subsp. novicida U112 competence lipoprotein ComL YP_898898.1 1335075 R 401614 CDS YP_898899.1 118497849 4547707 1335988..1336986 1 NC_008601.1 ribosomal large subunit pseudouridine synthase D 1336986 rluD 4547707 rluD Francisella tularensis subsp. novicida U112 ribosomal large subunit pseudouridine synthase D YP_898899.1 1335988 D 401614 CDS YP_898900.1 118497850 4547708 1336964..1337776 1 NC_008601.1 hypothetical protein 1337776 4547708 FTN_1265 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898900.1 1336964 D 401614 CDS YP_898901.1 118497851 4547709 1337851..1338951 1 NC_008601.1 ABC transporter membrane protein 1338951 4547709 FTN_1266 Francisella tularensis subsp. novicida U112 ABC transporter membrane protein YP_898901.1 1337851 D 401614 CDS YP_898902.1 118497852 4547710 1338966..1339727 1 NC_008601.1 ABC transporter ATP-binding protein 1339727 4547710 FTN_1267 Francisella tularensis subsp. novicida U112 ABC transporter ATP-binding protein YP_898902.1 1338966 D 401614 CDS YP_898903.1 118497853 4547711 1339737..1340462 1 NC_008601.1 hypothetical protein 1340462 4547711 FTN_1268 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898903.1 1339737 D 401614 CDS YP_898904.1 118497854 4547712 1340467..1341165 1 NC_008601.1 hypothetical protein 1341165 4547712 FTN_1269 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898904.1 1340467 D 401614 CDS YP_898905.1 118497855 4547713 complement(1341155..1341841) 1 NC_008601.1 hypothetical protein 1341841 4547713 FTN_1270 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898905.1 1341155 R 401614 CDS YP_898906.1 118497856 4547714 1341912..1342640 1 NC_008601.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 1342640 4547714 FTN_1271 Francisella tularensis subsp. novicida U112 16S ribosomal RNA methyltransferase RsmE YP_898906.1 1341912 D 401614 CDS YP_898907.1 118497857 4547715 1342876..1344360 1 NC_008601.1 proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter 1344360 4547715 FTN_1272 Francisella tularensis subsp. novicida U112 proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter YP_898907.1 1342876 D 401614 CDS YP_898908.1 118497858 4547716 1344468..1346159 1 NC_008601.1 long chain fatty acid CoA ligase 1346159 4547716 FTN_1273 Francisella tularensis subsp. novicida U112 long chain fatty acid CoA ligase YP_898908.1 1344468 D 401614 CDS YP_898909.1 118497859 4547717 complement(1346147..1346974) 1 NC_008601.1 AraC family transcriptional regulator 1346974 4547717 FTN_1274 Francisella tularensis subsp. novicida U112 AraC family transcriptional regulator YP_898909.1 1346147 R 401614 CDS YP_898910.1 118497860 4547718 1347139..1348668 1 NC_008601.1 drug:H+ antiporter-1 (DHA2) family protein 1348668 4547718 FTN_1275 Francisella tularensis subsp. novicida U112 drug:H+ antiporter-1 (DHA2) family protein YP_898910.1 1347139 D 401614 CDS YP_898911.1 118497861 4547719 1348690..1349715 1 NC_008601.1 membrane fusion protein 1349715 4547719 FTN_1276 Francisella tularensis subsp. novicida U112 membrane fusion protein YP_898911.1 1348690 D 401614 CDS YP_898912.1 118497862 4547720 1349725..1351197 1 NC_008601.1 outer membrane efflux protein 1351197 4547720 FTN_1277 Francisella tularensis subsp. novicida U112 outer membrane efflux protein YP_898912.1 1349725 D 401614 CDS YP_898913.1 118497863 4547625 1351324..1352073 1 NC_008601.1 NAD synthase 1352073 nadE 4547625 nadE Francisella tularensis subsp. novicida U112 NAD synthase YP_898913.1 1351324 D 401614 CDS YP_898914.1 118497864 4547626 1352177..1352599 1 NC_008601.1 hypothetical protein 1352599 4547626 FTN_1279 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898914.1 1352177 D 401614 CDS YP_898915.1 118497865 4547627 complement(1352699..1353265) 1 NC_008601.1 tryptophan repressor binding protein-like flavidoxin 1353265 4547627 FTN_1280 Francisella tularensis subsp. novicida U112 tryptophan repressor binding protein-like flavidoxin YP_898915.1 1352699 R 401614 CDS YP_898916.1 118497866 4547628 complement(1353280..1353978) 1 NC_008601.1 pirin family protein 1353978 4547628 FTN_1281 Francisella tularensis subsp. novicida U112 pirin family protein YP_898916.1 1353280 R 401614 CDS YP_898917.1 118497867 4547629 1354079..1354975 1 NC_008601.1 LysR family transcriptional regulator 1354975 4547629 FTN_1282 Francisella tularensis subsp. novicida U112 LysR family transcriptional regulator YP_898917.1 1354079 D 401614 CDS YP_898918.1 118497868 4547630 complement(1354989..1356176) 1 NC_008601.1 contains C-terminal Zn finger domain; chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 1356176 dnaJ 4547630 dnaJ Francisella tularensis subsp. novicida U112 chaperone protein DnaJ YP_898918.1 1354989 R 401614 CDS YP_898919.1 118497869 4547631 complement(1356202..1358130) 1 NC_008601.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 1358130 dnaK 4547631 dnaK Francisella tularensis subsp. novicida U112 molecular chaperone DnaK YP_898919.1 1356202 R 401614 CDS YP_898920.1 118497870 4547632 complement(1358231..1358818) 1 NC_008601.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 1358818 grpE 4547632 grpE Francisella tularensis subsp. novicida U112 heat shock protein GrpE YP_898920.1 1358231 R 401614 CDS YP_898921.1 118497871 4547633 1358907..1360073 1 NC_008601.1 membrane-bound lytic murein transglycosylase 1360073 mltA 4547633 mltA Francisella tularensis subsp. novicida U112 membrane-bound lytic murein transglycosylase YP_898921.1 1358907 D 401614 CDS YP_898922.1 118497872 4547634 1360066..1361250 1 NC_008601.1 hypothetical protein 1361250 hemG 4547634 hemG Francisella tularensis subsp. novicida U112 hypothetical protein YP_898922.1 1360066 D 401614 CDS YP_898923.1 118497873 4547635 1361389..1361817 1 NC_008601.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 1361817 rplM 4547635 rplM Francisella tularensis subsp. novicida U112 50S ribosomal protein L13 YP_898923.1 1361389 D 401614 CDS YP_898924.1 118497874 4547636 1361833..1362222 1 NC_008601.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 1362222 rpsI 4547636 rpsI Francisella tularensis subsp. novicida U112 30S ribosomal protein S9 YP_898924.1 1361833 D 401614 CDS YP_898925.1 118497875 4547637 1362282..1362899 1 NC_008601.1 macrophage growth locus, protein A 1362899 mglA 4547637 mglA Francisella tularensis subsp. novicida U112 macrophage growth locus, protein A YP_898925.1 1362282 D 401614 CDS YP_898926.1 118497876 4547638 1362901..1363308 1 NC_008601.1 ClpXP protease specificity-enhancing factor 1363308 mglB 4547638 mglB Francisella tularensis subsp. novicida U112 ClpXP protease specificity-enhancing factor YP_898926.1 1362901 D 401614 CDS YP_898927.1 118497877 4547639 complement(1363305..1364576) 1 NC_008601.1 solute:sodium symporter 1364576 4547639 FTN_1292 Francisella tularensis subsp. novicida U112 solute:sodium symporter YP_898927.1 1363305 R 401614 CDS YP_898928.1 118497878 4547640 complement(1364577..1365134) 1 NC_008601.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 1365134 rnhB 4547640 rnhB Francisella tularensis subsp. novicida U112 ribonuclease HII YP_898928.1 1364577 R 401614 CDS YP_898929.1 118497879 4547641 complement(1365136..1365879) 1 NC_008601.1 rRNA methylase 1365879 4547641 FTN_1294 Francisella tularensis subsp. novicida U112 rRNA methylase YP_898929.1 1365136 R 401614 CDS YP_898930.1 118497880 4547642 complement(1365872..1366327) 1 NC_008601.1 PEP-dependent sugar PTS system family protein 1366327 ptsN 4547642 ptsN Francisella tularensis subsp. novicida U112 PEP-dependent sugar PTS system family protein YP_898930.1 1365872 R 401614 CDS YP_898931.1 118497881 4547643 complement(1366364..1366660) 1 NC_008601.1 sigma54 modulation protein 1366660 4547643 FTN_1296 Francisella tularensis subsp. novicida U112 sigma54 modulation protein YP_898931.1 1366364 R 401614 CDS YP_898932.1 118497882 4548424 1366779..1367024 1 NC_008601.1 hypothetical protein 1367024 4548424 FTN_1297 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898932.1 1366779 D 401614 CDS YP_898933.1 118497883 4548425 1367030..1368382 1 NC_008601.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1368382 trmE 4548425 trmE Francisella tularensis subsp. novicida U112 tRNA modification GTPase TrmE YP_898933.1 1367030 D 401614 CDS YP_898934.1 118497884 4548426 complement(1368392..1368586) 1 NC_008601.1 hypothetical protein 1368586 4548426 FTN_1299 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898934.1 1368392 R 401614 CDS YP_898935.1 118497885 4548427 complement(1368607..1369497) 1 NC_008601.1 LysR family transcriptional regulator 1369497 4548427 FTN_1300 Francisella tularensis subsp. novicida U112 LysR family transcriptional regulator YP_898935.1 1368607 R 401614 CDS YP_898936.1 118497886 4548428 1369632..1370687 1 NC_008601.1 choloylglycine hydrolase family protein 1370687 4548428 FTN_1301 Francisella tularensis subsp. novicida U112 choloylglycine hydrolase family protein YP_898936.1 1369632 D 401614 CDS YP_898937.1 118497887 4548429 1370906..1371829 1 NC_008601.1 cysteine synthase 1371829 cysK 4548429 cysK Francisella tularensis subsp. novicida U112 cysteine synthase YP_898937.1 1370906 D 401614 CDS YP_898938.1 118497888 4548430 1372091..1372660 1 NC_008601.1 DsbB family disulfide bond formation protein 1372660 4548430 FTN_1303 Francisella tularensis subsp. novicida U112 DsbB family disulfide bond formation protein YP_898938.1 1372091 D 401614 CDS YP_898939.1 118497889 4548436 1378294..1380756 1 NC_008601.1 hypothetical protein 1380756 pdpA 4548436 pdpA Francisella tularensis subsp. novicida U112 hypothetical protein YP_898939.1 1378294 D 401614 CDS YP_898940.1 118497890 4548437 1380761..1384042 1 NC_008601.1 hypothetical protein 1384042 pdpB 4548437 pdpB Francisella tularensis subsp. novicida U112 hypothetical protein YP_898940.1 1380761 D 401614 CDS YP_898941.1 118497891 4548438 1384032..1384409 1 NC_008601.1 hypothetical protein 1384409 4548438 FTN_1311 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898941.1 1384032 D 401614 CDS YP_898942.1 118497892 4548114 1384422..1384916 1 NC_008601.1 hypothetical protein 1384916 4548114 FTN_1312 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898942.1 1384422 D 401614 CDS YP_898943.1 118497893 4548115 1384921..1386651 1 NC_008601.1 hypothetical protein 1386651 4548115 FTN_1313 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898943.1 1384921 D 401614 CDS YP_898944.1 118497894 4548116 1386652..1387173 1 NC_008601.1 hypothetical protein 1387173 4548116 FTN_1314 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898944.1 1386652 D 401614 CDS YP_898945.1 118497895 4548117 1387186..1388616 1 NC_008601.1 hypothetical protein 1388616 4548117 FTN_1315 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898945.1 1387186 D 401614 CDS YP_898946.1 118497896 4548118 1388629..1389252 1 NC_008601.1 hypothetical protein 1389252 4548118 FTN_1316 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898946.1 1388629 D 401614 CDS YP_898947.1 118497897 4548119 1389274..1390425 1 NC_008601.1 hypothetical protein 1390425 4548119 FTN_1317 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898947.1 1389274 D 401614 CDS YP_898948.1 118497898 4548120 1390391..1391164 1 NC_008601.1 hypothetical protein 1391164 4548120 FTN_1318 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898948.1 1390391 D 401614 CDS YP_898949.1 118497899 4548121 1391204..1395181 1 NC_008601.1 hypothetical protein 1395181 pdpC 4548121 pdpC Francisella tularensis subsp. novicida U112 hypothetical protein YP_898949.1 1391204 D 401614 CDS YP_898950.1 118497900 4548122 1395199..1395765 1 NC_008601.1 hypothetical protein 1395765 4548122 FTN_1320 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898950.1 1395199 D 401614 CDS YP_898951.1 118497901 4548123 complement(1395772..1396968) 1 NC_008601.1 intracellular growth locus protein D 1396968 iglD 4548123 iglD Francisella tularensis subsp. novicida U112 intracellular growth locus protein D YP_898951.1 1395772 R 401614 CDS YP_898952.1 118497902 4548124 complement(1396989..1397618) 1 NC_008601.1 intracellular growth locus protein C 1397618 iglC 4548124 iglC Francisella tularensis subsp. novicida U112 intracellular growth locus protein C YP_898952.1 1396989 R 401614 CDS YP_898953.1 118497903 4548125 complement(1397635..1399155) 1 NC_008601.1 intracellular growth locus protein B 1399155 iglB 4548125 iglB Francisella tularensis subsp. novicida U112 intracellular growth locus protein B YP_898953.1 1397635 R 401614 CDS YP_898954.1 118497904 4548126 complement(1399169..1399723) 1 NC_008601.1 intracellular growth locus protein A 1399723 iglA 4548126 iglA Francisella tularensis subsp. novicida U112 intracellular growth locus protein A YP_898954.1 1399169 R 401614 CDS YP_898955.1 118497905 4548127 complement(1399803..1403540) 1 NC_008601.1 hypothetical protein 1403540 pdpD 4548127 pdpD Francisella tularensis subsp. novicida U112 hypothetical protein YP_898955.1 1399803 R 401614 CDS YP_898956.1 118497906 4548128 complement(1403641..1404786) 1 NC_008601.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 1404786 anmK 4548128 anmK Francisella tularensis subsp. novicida U112 anhydro-N-acetylmuramic acid kinase YP_898956.1 1403641 R 401614 CDS YP_898957.1 118497907 4548130 1406119..1407573 1 NC_008601.1 trehalase 1407573 treA 4548130 treA Francisella tularensis subsp. novicida U112 trehalase YP_898957.1 1406119 D 401614 CDS YP_898958.1 118497908 4548131 complement(1407740..1408804) 1 NC_008601.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis; fructose-1,6-bisphosphate aldolase 1408804 fbaA 4548131 fbaA Francisella tularensis subsp. novicida U112 fructose-1,6-bisphosphate aldolase YP_898958.1 1407740 R 401614 CDS YP_898959.1 118497909 4548132 complement(1408820..1410256) 1 NC_008601.1 pyruvate kinase 1410256 pyk 4548132 pyk Francisella tularensis subsp. novicida U112 pyruvate kinase YP_898959.1 1408820 R 401614 CDS YP_898960.1 118497910 4547281 complement(1410272..1411450) 1 NC_008601.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 1411450 pgk 4547281 pgk Francisella tularensis subsp. novicida U112 phosphoglycerate kinase YP_898960.1 1410272 R 401614 CDS YP_898961.1 118497911 4547282 complement(1411469..1412470) 1 NC_008601.1 glyceraldehyde-3-phosphate dehydrogenase 1412470 gapA 4547282 gapA Francisella tularensis subsp. novicida U112 glyceraldehyde-3-phosphate dehydrogenase YP_898961.1 1411469 R 401614 CDS YP_898962.1 118497912 4547283 complement(1412508..1414499) 1 NC_008601.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1414499 tktA 4547283 tktA Francisella tularensis subsp. novicida U112 transketolase YP_898962.1 1412508 R 401614 CDS YP_898963.1 118497913 4547284 1414639..1415142 1 NC_008601.1 hypothetical protein 1415142 4547284 FTN_1334 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898963.1 1414639 D 401614 CDS YP_898964.1 118497914 4547285 1415186..1415368 1 NC_008601.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1415368 rpmF 4547285 rpmF Francisella tularensis subsp. novicida U112 50S ribosomal protein L32 YP_898964.1 1415186 D 401614 CDS YP_898965.1 118497915 4547286 1415467..1416513 1 NC_008601.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX 1416513 plsX 4547286 plsX Francisella tularensis subsp. novicida U112 putative glycerol-3-phosphate acyltransferase PlsX YP_898965.1 1415467 D 401614 CDS YP_898966.1 118497916 4547287 1416610..1417581 1 NC_008601.1 3-oxoacyl-ACP synthase 1417581 fabH 4547287 fabH Francisella tularensis subsp. novicida U112 3-oxoacyl-ACP synthase YP_898966.1 1416610 D 401614 CDS YP_898967.1 118497917 4547288 1417629..1418549 1 NC_008601.1 malonyl-CoA:ACP transacylase 1418549 fabD 4547288 fabD Francisella tularensis subsp. novicida U112 malonyl-CoA:ACP transacylase YP_898967.1 1417629 D 401614 CDS YP_898968.1 118497918 4547289 1418563..1419306 1 NC_008601.1 3-oxoacyl-(acyl-carrier-protein) reductase 1419306 fabG 4547289 fabG Francisella tularensis subsp. novicida U112 3-oxoacyl-(acyl-carrier-protein) reductase YP_898968.1 1418563 D 401614 CDS YP_898969.1 118497919 4547290 1419403..1419687 1 NC_008601.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1419687 acpP 4547290 acpP Francisella tularensis subsp. novicida U112 acyl carrier protein YP_898969.1 1419403 D 401614 CDS YP_898970.1 118497920 4547291 1419767..1421026 1 NC_008601.1 beta-ketoacyl-ACP synthase II 1421026 fabF 4547291 fabF Francisella tularensis subsp. novicida U112 beta-ketoacyl-ACP synthase II YP_898970.1 1419767 D 401614 CDS YP_898971.1 118497921 4547292 1421108..1421392 1 NC_008601.1 hypothetical protein 1421392 4547292 FTN_1342 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898971.1 1421108 D 401614 CDS YP_898972.1 118497922 4547293 complement(1421382..1422068) 1 NC_008601.1 hypothetical protein 1422068 4547293 FTN_1343 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898972.1 1421382 R 401614 CDS YP_898973.1 118497923 4547294 1422190..1423389 1 NC_008601.1 hypothetical protein 1423389 4547294 FTN_1344 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898973.1 1422190 D 401614 CDS YP_898974.1 118497924 4547295 1423503..1424555 1 NC_008601.1 hypothetical protein 1424555 4547295 FTN_1345 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898974.1 1423503 D 401614 CDS YP_898975.1 118497925 4547296 1424642..1425430 1 NC_008601.1 inositol monophosphatase family protein 1425430 4547296 FTN_1346 Francisella tularensis subsp. novicida U112 inositol monophosphatase family protein YP_898975.1 1424642 D 401614 CDS YP_898976.1 118497926 4547297 1425430..1426710 1 NC_008601.1 tRNA and rRNA cytosine-C5-methylases, sun protein 1426710 sun 4547297 sun Francisella tularensis subsp. novicida U112 tRNA and rRNA cytosine-C5-methylases, sun protein YP_898976.1 1425430 D 401614 CDS YP_898977.1 118497927 4547298 complement(1426688..1427179) 1 NC_008601.1 acetyltransferase 1427179 4547298 FTN_1348 Francisella tularensis subsp. novicida U112 acetyltransferase YP_898977.1 1426688 R 401614 CDS YP_898978.1 118497928 4547299 complement(1427272..1427817) 1 NC_008601.1 hypothetical protein 1427817 4547299 FTN_1349 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898978.1 1427272 R 401614 CDS YP_898979.1 118497929 4547300 complement(1427814..1429850) 1 NC_008601.1 DNA ligase 1429850 ligA 4547300 ligA Francisella tularensis subsp. novicida U112 DNA ligase YP_898979.1 1427814 R 401614 CDS YP_898980.1 118497930 4547908 1430157..1430873 1 NC_008601.1 hypothetical protein 1430873 4547908 FTN_1351 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898980.1 1430157 D 401614 CDS YP_898981.1 118497931 4547909 1430875..1431672 1 NC_008601.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 1431672 panB 4547909 panB Francisella tularensis subsp. novicida U112 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_898981.1 1430875 D 401614 CDS YP_898982.1 118497932 4547910 1431659..1432444 1 NC_008601.1 pantoate-beta-alanine ligase 1432444 panC 4547910 panC Francisella tularensis subsp. novicida U112 pantoate-beta-alanine ligase YP_898982.1 1431659 D 401614 CDS YP_898983.1 118497933 4547911 1432438..1432773 1 NC_008601.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 1432773 panD 4547911 panD Francisella tularensis subsp. novicida U112 aspartate alpha-decarboxylase YP_898983.1 1432438 D 401614 CDS YP_898984.1 118497934 4547912 1432777..1433547 1 NC_008601.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase 1433547 4547912 FTN_1355 Francisella tularensis subsp. novicida U112 pantothenate kinase YP_898984.1 1432777 D 401614 CDS YP_898985.1 118497935 4547913 complement(1433559..1435358) 1 NC_008601.1 exodeoxyribonuclease V subunit alpha 1435358 recD 4547913 recD Francisella tularensis subsp. novicida U112 exodeoxyribonuclease V subunit alpha YP_898985.1 1433559 R 401614 CDS YP_898986.1 118497936 4547914 complement(1435324..1438974) 1 NC_008601.1 ATP-dependent exonuclease V subunit beta 1438974 recB 4547914 recB Francisella tularensis subsp. novicida U112 ATP-dependent exonuclease V subunit beta YP_898986.1 1435324 R 401614 CDS YP_898987.1 118497937 4547915 complement(1439006..1439578) 1 NC_008601.1 hypothetical protein 1439578 4547915 FTN_1358 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898987.1 1439006 R 401614 CDS YP_898988.1 118497938 4547916 complement(1439520..1442759) 1 NC_008601.1 exodeoxyribonuclease V subunit gamma 1442759 recC 4547916 recC Francisella tularensis subsp. novicida U112 exodeoxyribonuclease V subunit gamma YP_898988.1 1439520 R 401614 CDS YP_898989.1 118497939 4547917 complement(1442836..1444422) 1 NC_008601.1 glutamate synthase domain-containing 2 1444422 gltB 4547917 gltB Francisella tularensis subsp. novicida U112 glutamate synthase domain-containing 2 YP_898989.1 1442836 R 401614 CDS YP_898990.1 118497940 4547918 1444600..1445469 1 NC_008601.1 drug/metabolite exporter 1445469 4547918 FTN_1361 Francisella tularensis subsp. novicida U112 drug/metabolite exporter YP_898990.1 1444600 D 401614 CDS YP_898991.1 118497941 4547919 complement(1445483..1445869) 1 NC_008601.1 hypothetical protein 1445869 4547919 FTN_1362 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898991.1 1445483 R 401614 CDS YP_898992.1 118497942 4547920 1446038..1446691 1 NC_008601.1 prophage repressor protein 1446691 4547920 FTN_1363 Francisella tularensis subsp. novicida U112 prophage repressor protein YP_898992.1 1446038 D 401614 CDS YP_898993.1 118497943 4548274 complement(1447265..1448899) 1 NC_008601.1 hypothetical protein 1448899 4548274 FTN_1367 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898993.1 1447265 R 401614 CDS YP_898994.1 118497944 4548275 complement(1448916..1449140) 1 NC_008601.1 Fe2+ transport system protein A 1449140 feoA 4548275 feoA Francisella tularensis subsp. novicida U112 Fe2+ transport system protein A YP_898994.1 1448916 R 401614 CDS YP_898995.1 118497945 4548276 1449249..1449956 1 NC_008601.1 hypothetical protein 1449956 4548276 FTN_1369 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898995.1 1449249 D 401614 CDS YP_898996.1 118497946 4548277 complement(1450034..1450792) 1 NC_008601.1 hydroxyacylglutathione hydrolase 1450792 gloB 4548277 gloB Francisella tularensis subsp. novicida U112 hydroxyacylglutathione hydrolase YP_898996.1 1450034 R 401614 CDS YP_898997.1 118497947 4548278 complement(1450806..1451963) 1 NC_008601.1 hypothetical protein 1451963 4548278 FTN_1371 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898997.1 1450806 R 401614 CDS YP_898998.1 118497948 4548279 complement(1451960..1453045) 1 NC_008601.1 hypothetical protein 1453045 4548279 FTN_1372 Francisella tularensis subsp. novicida U112 hypothetical protein YP_898998.1 1451960 R 401614 CDS YP_898999.1 118497949 4548280 complement(1453011..1453760) 1 NC_008601.1 uroporphyrinogen-III synthase 1453760 hemD 4548280 hemD Francisella tularensis subsp. novicida U112 uroporphyrinogen-III synthase YP_898999.1 1453011 R 401614 CDS YP_899000.1 118497950 4548281 complement(1453761..1454180) 1 NC_008601.1 sulfur acceptor protein SufE 1454180 sufE 4548281 sufE Francisella tularensis subsp. novicida U112 sulfur acceptor protein SufE YP_899000.1 1453761 R 401614 CDS YP_899001.1 118497951 4548283 1454884..1455420 1 NC_008601.1 DsbB family disulfide bond formation protein 1455420 4548283 FTN_1376 Francisella tularensis subsp. novicida U112 DsbB family disulfide bond formation protein YP_899001.1 1454884 D 401614 CDS YP_899002.1 118497952 4548284 1455684..1457381 1 NC_008601.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 1457381 proS 4548284 proS Francisella tularensis subsp. novicida U112 prolyl-tRNA synthetase YP_899002.1 1455684 D 401614 CDS YP_899003.1 118497953 4548285 1457390..1457929 1 NC_008601.1 hypothetical protein 1457929 4548285 FTN_1378 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899003.1 1457390 D 401614 CDS YP_899004.1 118497954 4548287 1459763..1460896 1 NC_008601.1 aspartate/tyrosine/aromatic aminotransferase 1460896 4548287 FTN_1380 Francisella tularensis subsp. novicida U112 aspartate/tyrosine/aromatic aminotransferase YP_899004.1 1459763 D 401614 CDS YP_899005.1 118497955 4548288 1460964..1462382 1 NC_008601.1 hypothetical protein 1462382 4548288 FTN_1381 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899005.1 1460964 D 401614 CDS YP_899006.1 118497956 4548289 complement(1462418..1462831) 1 NC_008601.1 hypothetical protein 1462831 4548289 FTN_1382 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899006.1 1462418 R 401614 CDS YP_899007.1 118497957 4548290 1463001..1463771 1 NC_008601.1 carbon-nitrogen hydrolase 1463771 4548290 FTN_1383 Francisella tularensis subsp. novicida U112 carbon-nitrogen hydrolase YP_899007.1 1463001 D 401614 CDS YP_899008.1 118497958 4548291 complement(1463755..1464180) 1 NC_008601.1 transcription termination factor 1464180 nusB 4548291 nusB Francisella tularensis subsp. novicida U112 transcription termination factor YP_899008.1 1463755 R 401614 CDS YP_899009.1 118497959 4547833 1464367..1464768 1 NC_008601.1 hypothetical protein 1464768 4547833 FTN_1385 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899009.1 1464367 D 401614 CDS YP_899010.1 118497960 4547834 1464785..1465297 1 NC_008601.1 hypothetical protein 1465297 4547834 FTN_1386 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899010.1 1464785 D 401614 CDS YP_899011.1 118497961 4547835 1465519..1465965 1 NC_008601.1 hypothetical protein 1465965 4547835 FTN_1387 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899011.1 1465519 D 401614 CDS YP_899012.1 118497962 4547836 1466005..1466625 1 NC_008601.1 oxidoreductase 1466625 4547836 FTN_1388 Francisella tularensis subsp. novicida U112 oxidoreductase YP_899012.1 1466005 D 401614 CDS YP_899013.1 118497963 4547837 complement(1466618..1467367) 1 NC_008601.1 hypothetical protein 1467367 4547837 FTN_1389 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899013.1 1466618 R 401614 CDS YP_899014.1 118497964 4547838 complement(1467369..1468055) 1 NC_008601.1 Zn-dependent hydrolase 1468055 4547838 FTN_1390 Francisella tularensis subsp. novicida U112 Zn-dependent hydrolase YP_899014.1 1467369 R 401614 CDS YP_899015.1 118497965 4547839 complement(1468100..1469791) 1 NC_008601.1 NAD(FAD)-dependent dehydrogenase 1469791 naoX 4547839 naoX Francisella tularensis subsp. novicida U112 NAD(FAD)-dependent dehydrogenase YP_899015.1 1468100 R 401614 CDS YP_899016.1 118497966 4547840 complement(1469816..1470334) 1 NC_008601.1 rhodanese-related sulfurtransferase 1470334 4547840 FTN_1392 Francisella tularensis subsp. novicida U112 rhodanese-related sulfurtransferase YP_899016.1 1469816 R 401614 CDS YP_899017.1 118497967 4547841 complement(1470396..1470698) 1 NC_008601.1 ArsR family transcriptional regulator 1470698 4547841 FTN_1393 Francisella tularensis subsp. novicida U112 ArsR family transcriptional regulator YP_899017.1 1470396 R 401614 CDS YP_899018.1 118497968 4547842 complement(1471519..1471791) 1 NC_008601.1 hypothetical protein 1471791 4547842 FTN_1394 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899018.1 1471519 R 401614 CDS YP_899019.1 118497969 4547843 complement(1471772..1472776) 1 NC_008601.1 hypothetical protein 1472776 4547843 FTN_1395 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899019.1 1471772 R 401614 CDS YP_899020.1 118497970 4547844 complement(1472780..1473271) 1 NC_008601.1 endonuclease 1473271 4547844 FTN_1396 Francisella tularensis subsp. novicida U112 endonuclease YP_899020.1 1472780 R 401614 CDS YP_899021.1 118497971 4547845 complement(1473442..1477344) 1 NC_008601.1 hypothetical protein 1477344 4547845 FTN_1397 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899021.1 1473442 R 401614 CDS YP_899022.1 118497972 4547846 complement(1477432..1477947) 1 NC_008601.1 acetyltransferase 1477947 4547846 FTN_1398 Francisella tularensis subsp. novicida U112 acetyltransferase YP_899022.1 1477432 R 401614 CDS YP_899023.1 118497973 4547847 complement(1477952..1478668) 1 NC_008601.1 hypothetical protein 1478668 4547847 FTN_1399 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899023.1 1477952 R 401614 CDS YP_899024.1 118497974 4547848 complement(1478678..1479367) 1 NC_008601.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 1479367 trmB 4547848 trmB Francisella tularensis subsp. novicida U112 tRNA (guanine-N(7)-)-methyltransferase YP_899024.1 1478678 R 401614 CDS YP_899025.1 118497975 4547849 1479437..1480072 1 NC_008601.1 homoserine/threonine efflux family protein 1480072 rhtB 4547849 rhtB Francisella tularensis subsp. novicida U112 homoserine/threonine efflux family protein YP_899025.1 1479437 D 401614 CDS YP_899026.1 118497976 4547850 complement(1480069..1480959) 1 NC_008601.1 NAD kinase 1480959 ppnK 4547850 ppnK Francisella tularensis subsp. novicida U112 NAD kinase YP_899026.1 1480069 R 401614 CDS YP_899027.1 118497977 4547851 1481150..1482094 1 NC_008601.1 glycosyl transferase family protein 1482094 gtrB 4547851 gtrB Francisella tularensis subsp. novicida U112 glycosyl transferase family protein YP_899027.1 1481150 D 401614 CDS YP_899028.1 118497978 4547852 complement(1482098..1482877) 1 NC_008601.1 ATP-binding cassette (ABC) superfamily protein 1482877 4547852 FTN_1404 Francisella tularensis subsp. novicida U112 ATP-binding cassette (ABC) superfamily protein YP_899028.1 1482098 R 401614 CDS YP_899029.1 118497979 4547780 complement(1482886..1483809) 1 NC_008601.1 ABC transporter ATP-binding protein 1483809 4547780 FTN_1405 Francisella tularensis subsp. novicida U112 ABC transporter ATP-binding protein YP_899029.1 1482886 R 401614 CDS YP_899030.1 118497980 4547781 complement(1483910..1484686) 1 NC_008601.1 hypothetical protein 1484686 4547781 FTN_1406 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899030.1 1483910 R 401614 CDS YP_899031.1 118497981 4547782 complement(1484686..1485012) 1 NC_008601.1 hypothetical protein 1485012 4547782 FTN_1407 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899031.1 1484686 R 401614 CDS YP_899032.1 118497982 4547783 complement(1485138..1485905) 1 NC_008601.1 Mg-dependent DNase 1485905 4547783 FTN_1408 Francisella tularensis subsp. novicida U112 Mg-dependent DNase YP_899032.1 1485138 R 401614 CDS YP_899033.1 118497983 4547784 complement(1485988..1487373) 1 NC_008601.1 major facilitator transporter 1487373 4547784 FTN_1409 Francisella tularensis subsp. novicida U112 major facilitator transporter YP_899033.1 1485988 R 401614 CDS YP_899034.1 118497984 4547785 1487622..1488062 1 NC_008601.1 bacterioferritin 1488062 bfr 4547785 bfr Francisella tularensis subsp. novicida U112 bacterioferritin YP_899034.1 1487622 D 401614 CDS YP_899035.1 118497985 4547787 complement(1488679..1489635) 1 NC_008601.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 1489635 4547787 FTN_1412 Francisella tularensis subsp. novicida U112 DNA-directed RNA polymerase subunit alpha YP_899035.1 1488679 R 401614 CDS YP_899036.1 118497986 4547788 complement(1489723..1490961) 1 NC_008601.1 related to the helicase subunit of the Holliday junction resolvase; recombination factor protein RarA 1490961 4547788 FTN_1413 Francisella tularensis subsp. novicida U112 recombination factor protein RarA YP_899036.1 1489723 R 401614 CDS YP_899037.1 118497987 4547789 complement(1491205..1492131) 1 NC_008601.1 exopolyphosphatase 1492131 ppx 4547789 ppx Francisella tularensis subsp. novicida U112 exopolyphosphatase YP_899037.1 1491205 R 401614 CDS YP_899038.1 118497988 4547790 1492329..1492652 1 NC_008601.1 thioredoxin 1492652 4547790 FTN_1415 Francisella tularensis subsp. novicida U112 thioredoxin YP_899038.1 1492329 D 401614 CDS YP_899039.1 118497989 4547791 1492695..1493957 1 NC_008601.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 1493957 rho 4547791 rho Francisella tularensis subsp. novicida U112 transcription termination factor Rho YP_899039.1 1492695 D 401614 CDS YP_899040.1 118497990 4547792 complement(1494297..1495781) 1 NC_008601.1 phosphomannomutase 1495781 manB 4547792 manB Francisella tularensis subsp. novicida U112 phosphomannomutase YP_899040.1 1494297 R 401614 CDS YP_899041.1 118497991 4547793 complement(1495811..1497217) 1 NC_008601.1 mannose-1-phosphate guanylyltransferase 1497217 manC 4547793 manC Francisella tularensis subsp. novicida U112 mannose-1-phosphate guanylyltransferase YP_899041.1 1495811 R 401614 CDS YP_899042.1 118497992 4547795 complement(1498686..1499933) 1 NC_008601.1 O antigen flippase 1499933 wzx 4547795 wzx Francisella tularensis subsp. novicida U112 O antigen flippase YP_899042.1 1498686 R 401614 CDS YP_899043.1 118497993 4547796 complement(1499938..1501830) 1 NC_008601.1 glutamine amidotransferase/asparagine synthase 1501830 wbtH 4547796 wbtH Francisella tularensis subsp. novicida U112 glutamine amidotransferase/asparagine synthase YP_899043.1 1499938 R 401614 CDS YP_899044.1 118497994 4548348 complement(1501832..1502944) 1 NC_008601.1 group 1 glycosyl transferase 1502944 wbtN 4548348 wbtN Francisella tularensis subsp. novicida U112 group 1 glycosyl transferase YP_899044.1 1501832 R 401614 CDS YP_899045.1 118497995 4548349 complement(1502937..1504025) 1 NC_008601.1 group 1 glycosyl transferase 1504025 wbtG 4548349 wbtG Francisella tularensis subsp. novicida U112 group 1 glycosyl transferase YP_899045.1 1502937 R 401614 CDS YP_899046.1 118497996 4548350 complement(1503991..1505283) 1 NC_008601.1 hypothetical protein 1505283 4548350 FTN_1424 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899046.1 1503991 R 401614 CDS YP_899047.1 118497997 4548351 complement(1505280..1506254) 1 NC_008601.1 NAD dependent epimerase 1506254 wbtF 4548351 wbtF Francisella tularensis subsp. novicida U112 NAD dependent epimerase YP_899047.1 1505280 R 401614 CDS YP_899048.1 118497998 4548352 complement(1506254..1507564) 1 NC_008601.1 UDP-glucose/GDP-mannose dehydrogenase 1507564 wbtE 4548352 wbtE Francisella tularensis subsp. novicida U112 UDP-glucose/GDP-mannose dehydrogenase YP_899048.1 1506254 R 401614 CDS YP_899049.1 118497999 4548353 complement(1507568..1508659) 1 NC_008601.1 group 1 glycosyl transferase 1508659 wbtD 4548353 wbtD Francisella tularensis subsp. novicida U112 group 1 glycosyl transferase YP_899049.1 1507568 R 401614 CDS YP_899050.1 118498000 4548354 complement(1508656..1509267) 1 NC_008601.1 transferase 1509267 wbtO 4548354 wbtO Francisella tularensis subsp. novicida U112 transferase YP_899050.1 1508656 R 401614 CDS YP_899051.1 118498001 4548355 complement(1509257..1509886) 1 NC_008601.1 galactosyl transferase 1509886 wbtP 4548355 wbtP Francisella tularensis subsp. novicida U112 galactosyl transferase YP_899051.1 1509257 R 401614 CDS YP_899052.1 118498002 4548356 complement(1509876..1510991) 1 NC_008601.1 aminotransferase 1510991 wbtQ 4548356 wbtQ Francisella tularensis subsp. novicida U112 aminotransferase YP_899052.1 1509876 R 401614 CDS YP_899053.1 118498003 4548357 complement(1510997..1512733) 1 NC_008601.1 dTDP-glucose 4,6-dehydratase 1512733 wbtA 4548357 wbtA Francisella tularensis subsp. novicida U112 dTDP-glucose 4,6-dehydratase YP_899053.1 1510997 R 401614 CDS YP_899054.1 118498004 4548358 complement(1513192..1517211) 1 NC_008601.1 HrpA-like helicase 1517211 hrpA 4548358 hrpA Francisella tularensis subsp. novicida U112 HrpA-like helicase YP_899054.1 1513192 R 401614 CDS YP_899055.1 118498005 4548359 complement(1517235..1518122) 1 NC_008601.1 hypothetical protein 1518122 4548359 FTN_1433 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899055.1 1517235 R 401614 CDS YP_899056.1 118498006 4548360 complement(1518136..1520352) 1 NC_008601.1 isocitrate dehydrogenase 1520352 icd 4548360 icd Francisella tularensis subsp. novicida U112 isocitrate dehydrogenase YP_899056.1 1518136 R 401614 CDS YP_899057.1 118498007 4548361 complement(1520401..1520820) 1 NC_008601.1 arsenate reductase 1520820 4548361 FTN_1435 Francisella tularensis subsp. novicida U112 arsenate reductase YP_899057.1 1520401 R 401614 CDS YP_899058.1 118498008 4548362 1520964..1522652 1 NC_008601.1 long chain fatty acid CoA ligase 1522652 fadD 4548362 fadD Francisella tularensis subsp. novicida U112 long chain fatty acid CoA ligase YP_899058.1 1520964 D 401614 CDS YP_899059.1 118498009 4548363 1522690..1524930 1 NC_008601.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase 1524930 fadE 4548363 fadE Francisella tularensis subsp. novicida U112 acyl-CoA dehydrogenase YP_899059.1 1522690 D 401614 CDS YP_899060.1 118498010 4548364 1525003..1527699 1 NC_008601.1 fusion product of 3-hydroxacyl-CoA dehydrogenase and acyl-CoA-binding protein 1527699 4548364 FTN_1438 Francisella tularensis subsp. novicida U112 fusion product of 3-hydroxacyl-CoA dehydrogenase and acyl-CoA-binding protein YP_899060.1 1525003 D 401614 CDS YP_899061.1 118498011 4548365 1527712..1528899 1 NC_008601.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 1528899 fadA 4548365 fadA Francisella tularensis subsp. novicida U112 acetyl-CoA acetyltransferase YP_899061.1 1527712 D 401614 CDS YP_899062.1 118498012 4548366 1528961..1529449 1 NC_008601.1 hypothetical protein 1529449 4548366 FTN_1440 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899062.1 1528961 D 401614 CDS YP_899063.1 118498013 4548367 complement(1529442..1530722) 1 NC_008601.1 sugar porter (SP) family protein 1530722 4548367 FTN_1441 Francisella tularensis subsp. novicida U112 sugar porter (SP) family protein YP_899063.1 1529442 R 401614 CDS YP_899064.1 118498014 4547924 complement(1530872..1531099) 1 NC_008601.1 hypothetical protein 1531099 4547924 FTN_1442 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899064.1 1530872 R 401614 CDS YP_899065.1 118498015 4547925 complement(1531184..1532599) 1 NC_008601.1 putative nicotinate phosphoribosyltransferase 1532599 4547925 FTN_1443 Francisella tularensis subsp. novicida U112 putative nicotinate phosphoribosyltransferase YP_899065.1 1531184 R 401614 CDS YP_899066.1 118498016 4547926 complement(1532670..1533686) 1 NC_008601.1 mu-crystallin homolog; catalyzes the formation of L-proline from L-ornithine; ornithine cyclodeaminase 1533686 4547926 FTN_1444 Francisella tularensis subsp. novicida U112 ornithine cyclodeaminase YP_899066.1 1532670 R 401614 CDS YP_899067.1 118498017 4547927 complement(1533934..1534848) 1 NC_008601.1 hypothetical protein 1534848 4547927 FTN_1445 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899067.1 1533934 R 401614 CDS YP_899068.1 118498018 4547928 complement(1534988..1536382) 1 NC_008601.1 hypothetical protein 1536382 4547928 FTN_1446 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899068.1 1534988 R 401614 CDS YP_899069.1 118498019 4547929 complement(1536388..1537371) 1 NC_008601.1 hypothetical protein 1537371 4547929 FTN_1447 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899069.1 1536388 R 401614 CDS YP_899070.1 118498020 4547930 complement(1537382..1538812) 1 NC_008601.1 hypothetical protein 1538812 4547930 FTN_1448 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899070.1 1537382 R 401614 CDS YP_899071.1 118498021 4547931 complement(1538869..1539477) 1 NC_008601.1 hypothetical protein 1539477 4547931 FTN_1449 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899071.1 1538869 R 401614 CDS YP_899072.1 118498022 4547932 complement(1539652..1540053) 1 NC_008601.1 hypothetical protein 1540053 4547932 FTN_1450 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899072.1 1539652 R 401614 CDS YP_899073.1 118498023 4547933 complement(1540171..1540707) 1 NC_008601.1 hypothetical protein 1540707 4547933 FTN_1451 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899073.1 1540171 R 401614 CDS YP_899074.1 118498024 4547934 1540850..1541539 1 NC_008601.1 two-component response regulator 1541539 4547934 FTN_1452 Francisella tularensis subsp. novicida U112 two-component response regulator YP_899074.1 1540850 D 401614 CDS YP_899075.1 118498025 4547935 1541523..1542560 1 NC_008601.1 two-component regulator, sensor histidine kinase 1542560 4547935 FTN_1453 Francisella tularensis subsp. novicida U112 two-component regulator, sensor histidine kinase YP_899075.1 1541523 D 401614 CDS YP_899076.1 118498026 4547936 1542637..1543890 1 NC_008601.1 NAD/FAD-binding protein 1543890 4547936 FTN_1454 Francisella tularensis subsp. novicida U112 NAD/FAD-binding protein YP_899076.1 1542637 D 401614 CDS YP_899077.1 118498027 4547937 1543884..1544660 1 NC_008601.1 hypothetical protein 1544660 4547937 FTN_1455 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899077.1 1543884 D 401614 CDS YP_899078.1 118498028 4547938 1544780..1545943 1 NC_008601.1 cyclopropane fatty acid synthase, methyltransferase 1545943 cfa 4547938 cfa Francisella tularensis subsp. novicida U112 cyclopropane fatty acid synthase, methyltransferase YP_899078.1 1544780 D 401614 CDS YP_899079.1 118498029 4547939 1545936..1546454 1 NC_008601.1 hypothetical protein 1546454 4547939 FTN_1457 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899079.1 1545936 D 401614 CDS YP_899080.1 118498030 4547940 1546487..1546993 1 NC_008601.1 hypothetical protein 1546993 4547940 FTN_1458 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899080.1 1546487 D 401614 CDS YP_899081.1 118498031 4547941 1546995..1547738 1 NC_008601.1 short chain dehydrogenase 1547738 4547941 FTN_1459 Francisella tularensis subsp. novicida U112 short chain dehydrogenase YP_899081.1 1546995 D 401614 CDS YP_899082.1 118498032 4547942 1547752..1548582 1 NC_008601.1 delta 9 acyl-lipid fatty acid desaturase 1548582 4547942 FTN_1460 Francisella tularensis subsp. novicida U112 delta 9 acyl-lipid fatty acid desaturase YP_899082.1 1547752 D 401614 CDS YP_899083.1 118498033 4548556 complement(1548606..1550903) 1 NC_008601.1 ribonuclease R 1550903 rnr 4548556 rnr Francisella tularensis subsp. novicida U112 ribonuclease R YP_899083.1 1548606 R 401614 CDS YP_899084.1 118498034 4548557 complement(1550896..1551804) 1 NC_008601.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 1551804 truB 4548557 truB Francisella tularensis subsp. novicida U112 tRNA pseudouridine synthase B YP_899084.1 1550896 R 401614 CDS YP_899085.1 118498035 4548558 complement(1551791..1552483) 1 NC_008601.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 1552483 rnc 4548558 rnc Francisella tularensis subsp. novicida U112 ribonuclease III YP_899085.1 1551791 R 401614 CDS YP_899086.1 118498036 4548559 complement(1552490..1553353) 1 NC_008601.1 signal peptidase I 1553353 lepB 4548559 lepB Francisella tularensis subsp. novicida U112 signal peptidase I YP_899086.1 1552490 R 401614 CDS YP_899087.1 118498037 4548560 complement(1553358..1554044) 1 NC_008601.1 two-component response regulator 1554044 4548560 FTN_1465 Francisella tularensis subsp. novicida U112 two-component response regulator YP_899087.1 1553358 R 401614 CDS YP_899088.1 118498038 4548561 complement(1554485..1555576) 1 NC_008601.1 hypothetical protein 1555576 4548561 FTN_1466 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899088.1 1554485 R 401614 CDS YP_899089.1 118498039 4548562 complement(1555813..1556637) 1 NC_008601.1 pyrroline-5-carboxylate reductase 1556637 proC 4548562 proC Francisella tularensis subsp. novicida U112 pyrroline-5-carboxylate reductase YP_899089.1 1555813 R 401614 CDS YP_899090.1 118498040 4548563 1556744..1557322 1 NC_008601.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; putative deoxyribonucleotide triphosphate pyrophosphatase 1557322 4548563 FTN_1468 Francisella tularensis subsp. novicida U112 putative deoxyribonucleotide triphosphate pyrophosphatase YP_899090.1 1556744 D 401614 CDS YP_899091.1 118498041 4548564 1557427..1558722 1 NC_008601.1 3-deoxy-D-manno-octulosonic-acid transferase 1558722 kdtA 4548564 kdtA Francisella tularensis subsp. novicida U112 3-deoxy-D-manno-octulosonic-acid transferase YP_899091.1 1557427 D 401614 CDS YP_899092.1 118498042 4548565 1558719..1559600 1 NC_008601.1 geranyl diphosphate synthase/farnesyl diphosphate synthase 1559600 ispA 4548565 ispA Francisella tularensis subsp. novicida U112 geranyl diphosphate synthase/farnesyl diphosphate synthase YP_899092.1 1558719 D 401614 CDS YP_899093.1 118498043 4548566 1559648..1560412 1 NC_008601.1 phosphatidylcholine synthase 1560412 pcs 4548566 pcs Francisella tularensis subsp. novicida U112 phosphatidylcholine synthase YP_899093.1 1559648 D 401614 CDS YP_899094.1 118498044 4548567 1560482..1561291 1 NC_008601.1 hypothetical protein 1561291 4548567 FTN_1472 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899094.1 1560482 D 401614 CDS YP_899095.1 118498045 4548569 complement(1561671..1562807) 1 NC_008601.1 glycosyl hydrolase family protein 1562807 bglX 4548569 bglX Francisella tularensis subsp. novicida U112 glycosyl hydrolase family protein YP_899095.1 1561671 R 401614 CDS YP_899096.1 118498046 4548570 complement(1563109..1563483) 1 NC_008601.1 hypothetical protein 1563483 4548570 FTN_1475 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899096.1 1563109 R 401614 CDS YP_899097.1 118498047 4548571 complement(1563574..1564161) 1 NC_008601.1 hypothetical protein 1564161 4548571 FTN_1476 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899097.1 1563574 R 401614 CDS YP_899098.1 118498048 4548572 complement(1564221..1565363) 1 NC_008601.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 1565363 lpxB 4548572 lpxB Francisella tularensis subsp. novicida U112 lipid-A-disaccharide synthase YP_899098.1 1564221 R 401614 CDS YP_899099.1 118498049 4548573 complement(1565363..1566142) 1 NC_008601.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 1566142 lpxA 4548573 lpxA Francisella tularensis subsp. novicida U112 UDP-N-acetylglucosamine acyltransferase YP_899099.1 1565363 R 401614 CDS YP_899100.1 118498050 4548574 complement(1566145..1566636) 1 NC_008601.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 1566636 fabZ 4548574 fabZ Francisella tularensis subsp. novicida U112 (3R)-hydroxymyristoyl-ACP dehydratase YP_899100.1 1566145 R 401614 CDS YP_899101.1 118498051 4548518 complement(1566651..1567664) 1 NC_008601.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 1567664 lpxD 4548518 lpxD Francisella tularensis subsp. novicida U112 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_899101.1 1566651 R 401614 CDS YP_899102.1 118498052 4548519 complement(1567683..1568186) 1 NC_008601.1 outer membrane protein OmpH 1568186 ompH 4548519 ompH Francisella tularensis subsp. novicida U112 outer membrane protein OmpH YP_899102.1 1567683 R 401614 CDS YP_899103.1 118498053 4548520 complement(1568322..1570700) 1 NC_008601.1 hypothetical protein 1570700 4548520 FTN_1482 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899103.1 1568322 R 401614 CDS YP_899104.1 118498054 4548521 complement(1570706..1571863) 1 NC_008601.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1571863 dxr 4548521 dxr Francisella tularensis subsp. novicida U112 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_899104.1 1570706 R 401614 CDS YP_899105.1 118498055 4548522 complement(1571869..1574475) 1 NC_008601.1 DNA gyrase subunit A 1574475 gyrA 4548522 gyrA Francisella tularensis subsp. novicida U112 DNA gyrase subunit A YP_899105.1 1571869 R 401614 CDS YP_899106.1 118498056 4548523 1574733..1576400 1 NC_008601.1 chitin-binding protein 1576400 cbpA 4548523 cbpA Francisella tularensis subsp. novicida U112 chitin-binding protein YP_899106.1 1574733 D 401614 CDS YP_899107.1 118498057 4548524 complement(1576434..1577096) 1 NC_008601.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 1577096 ung 4548524 ung Francisella tularensis subsp. novicida U112 uracil-DNA glycosylase YP_899107.1 1576434 R 401614 CDS YP_899108.1 118498058 4548525 complement(1577093..1579960) 1 NC_008601.1 restriction endonuclease 1579960 4548525 FTN_1487 Francisella tularensis subsp. novicida U112 restriction endonuclease YP_899108.1 1577093 R 401614 CDS YP_899109.1 118498059 4548526 complement(1579950..1580906) 1 NC_008601.1 prophage maintenance system killer protein (DOC) 1580906 4548526 FTN_1488 Francisella tularensis subsp. novicida U112 prophage maintenance system killer protein (DOC) YP_899109.1 1579950 R 401614 CDS YP_899110.1 118498060 4548527 complement(1581018..1581764) 1 NC_008601.1 hypothetical protein 1581764 4548527 FTN_1489 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899110.1 1581018 R 401614 CDS YP_899111.1 118498061 4548528 complement(1581776..1582627) 1 NC_008601.1 hypothetical protein 1582627 4548528 FTN_1490 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899111.1 1581776 R 401614 CDS YP_899112.1 118498062 4548529 complement(1582627..1584609) 1 NC_008601.1 adenine specific DNA methylase 1584609 4548529 FTN_1491 Francisella tularensis subsp. novicida U112 adenine specific DNA methylase YP_899112.1 1582627 R 401614 CDS YP_899113.1 118498063 4548530 complement(1584791..1586203) 1 NC_008601.1 dihydrolipoamide dehydrogenase 1586203 lpdA 4548530 lpdA Francisella tularensis subsp. novicida U112 dihydrolipoamide dehydrogenase YP_899113.1 1584791 R 401614 CDS YP_899114.1 118498064 4548531 complement(1586217..1588112) 1 NC_008601.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase 1588112 aceF 4548531 aceF Francisella tularensis subsp. novicida U112 dihydrolipoamide acetyltransferase YP_899114.1 1586217 R 401614 CDS YP_899115.1 118498065 4548532 complement(1588130..1590811) 1 NC_008601.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 1590811 aceE 4548532 aceE Francisella tularensis subsp. novicida U112 pyruvate dehydrogenase subunit E1 YP_899115.1 1588130 R 401614 CDS YP_899116.1 118498066 4548533 complement(1591111..1592298) 1 NC_008601.1 hypothetical protein 1592298 4548533 FTN_1495 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899116.1 1591111 R 401614 CDS YP_899117.1 118498067 4548534 1592378..1592992 1 NC_008601.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 1592992 coaE 4548534 coaE Francisella tularensis subsp. novicida U112 dephospho-CoA kinase YP_899117.1 1592378 D 401614 CDS YP_899118.1 118498068 4547339 1593289..1594293 1 NC_008601.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 1594293 trpS 4547339 trpS Francisella tularensis subsp. novicida U112 tryptophanyl-tRNA synthetase YP_899118.1 1593289 D 401614 CDS YP_899119.1 118498069 4547340 1594295..1595020 1 NC_008601.1 hypothetical protein 1595020 4547340 FTN_1500 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899119.1 1594295 D 401614 CDS YP_899120.1 118498070 4547341 1595030..1596328 1 NC_008601.1 monovalent cation:proton antiporter-1 1596328 4547341 FTN_1501 Francisella tularensis subsp. novicida U112 monovalent cation:proton antiporter-1 YP_899120.1 1595030 D 401614 CDS YP_899121.1 118498071 4547342 complement(1596727..1597764) 1 NC_008601.1 hypothetical protein 1597764 4547342 FTN_1502 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899121.1 1596727 R 401614 CDS YP_899122.1 118498072 4547343 complement(1598261..1598656) 1 NC_008601.1 hypothetical protein 1598656 4547343 FTN_1503 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899122.1 1598261 R 401614 CDS YP_899123.1 118498073 4547344 complement(1598658..1599542) 1 NC_008601.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase 1599542 murQ 4547344 murQ Francisella tularensis subsp. novicida U112 N-acetylmuramic acid 6-phosphate etherase YP_899123.1 1598658 R 401614 CDS YP_899124.1 118498074 4547345 complement(1599539..1601503) 1 NC_008601.1 hypothetical protein 1601503 4547345 FTN_1505 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899124.1 1599539 R 401614 CDS YP_899125.1 118498075 4547346 complement(1601512..1602525) 1 NC_008601.1 hypothetical protein 1602525 4547346 FTN_1506 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899125.1 1601512 R 401614 CDS YP_899126.1 118498076 4547347 complement(1602506..1603009) 1 NC_008601.1 hypothetical protein 1603009 4547347 FTN_1507 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899126.1 1602506 R 401614 CDS YP_899127.1 118498077 4547348 complement(1603029..1603976) 1 NC_008601.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 1603976 accA 4547348 accA Francisella tularensis subsp. novicida U112 acetyl-CoA carboxylase carboxyltransferase subunit alpha YP_899127.1 1603029 R 401614 CDS YP_899128.1 118498078 4547349 1604143..1606677 1 NC_008601.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 1606677 mutS 4547349 mutS Francisella tularensis subsp. novicida U112 DNA mismatch repair protein MutS YP_899128.1 1604143 D 401614 CDS YP_899129.1 118498079 4547350 1606754..1607197 1 NC_008601.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 1607197 secB2 4547350 secB2 Francisella tularensis subsp. novicida U112 preprotein translocase subunit SecB YP_899129.1 1606754 D 401614 CDS YP_899130.1 118498080 4547351 1607392..1608615 1 NC_008601.1 hypothetical protein 1608615 4547351 FTN_1511 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899130.1 1607392 D 401614 CDS YP_899131.1 118498081 4547352 1608678..1609850 1 NC_008601.1 hydroxy/aromatic amino acid permease (HAAAP) family protein 1609850 4547352 FTN_1512 Francisella tularensis subsp. novicida U112 hydroxy/aromatic amino acid permease (HAAAP) family protein YP_899131.1 1608678 D 401614 CDS YP_899132.1 118498082 4547353 1609860..1610738 1 NC_008601.1 site-specific recombinase 1610738 xerC 4547353 xerC Francisella tularensis subsp. novicida U112 site-specific recombinase YP_899132.1 1609860 D 401614 CDS YP_899133.1 118498083 4547354 1610738..1611463 1 NC_008601.1 hypothetical protein 1611463 4547354 FTN_1514 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899133.1 1610738 D 401614 CDS YP_899134.1 118498084 4547355 complement(1611470..1612084) 1 NC_008601.1 hypothetical protein 1612084 4547355 FTN_1515 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899134.1 1611470 R 401614 CDS YP_899135.1 118498085 4547356 1612172..1612750 1 NC_008601.1 hypothetical protein 1612750 4547356 FTN_1516 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899135.1 1612172 D 401614 CDS YP_899136.1 118498086 4548170 1612827..1613459 1 NC_008601.1 hypothetical protein 1613459 4548170 FTN_1517 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899136.1 1612827 D 401614 CDS YP_899137.1 118498087 4548171 complement(1614438..1616447) 1 NC_008601.1 GDP pyrophosphokinase/GTP pyrophosphokinase 1616447 relA 4548171 relA Francisella tularensis subsp. novicida U112 GDP pyrophosphokinase/GTP pyrophosphokinase YP_899137.1 1614438 R 401614 CDS YP_899138.1 118498088 4548172 complement(1616750..1617106) 1 NC_008601.1 hypothetical protein 1617106 4548172 FTN_1519 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899138.1 1616750 R 401614 CDS YP_899139.1 118498089 4548173 complement(1617140..1618336) 1 NC_008601.1 hydroxy/aromatic amino acid permease (HAAAP) family protein 1618336 4548173 FTN_1520 Francisella tularensis subsp. novicida U112 hydroxy/aromatic amino acid permease (HAAAP) family protein YP_899139.1 1617140 R 401614 CDS YP_899140.1 118498090 4548174 1618541..1619425 1 NC_008601.1 drug/metabolite exporter protein 1619425 4548174 FTN_1521 Francisella tularensis subsp. novicida U112 drug/metabolite exporter protein YP_899140.1 1618541 D 401614 CDS YP_899141.1 118498091 4548175 complement(1619415..1620341) 1 NC_008601.1 subunit of DnaJ/DnaK/GrpE 1620341 4548175 FTN_1522 Francisella tularensis subsp. novicida U112 subunit of DnaJ/DnaK/GrpE YP_899141.1 1619415 R 401614 CDS YP_899142.1 118498092 4548176 1620541..1621254 1 NC_008601.1 amino acid-polyamine-organocation family protein 1621254 4548176 FTN_1523 Francisella tularensis subsp. novicida U112 amino acid-polyamine-organocation family protein YP_899142.1 1620541 D 401614 CDS YP_899143.1 118498093 4548177 complement(1621269..1621652) 1 NC_008601.1 hypothetical protein 1621652 4548177 FTN_1524 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899143.1 1621269 R 401614 CDS YP_899144.1 118498094 4548178 complement(1621649..1622248) 1 NC_008601.1 phosphatidyltransferase 1622248 4548178 FTN_1525 Francisella tularensis subsp. novicida U112 phosphatidyltransferase YP_899144.1 1621649 R 401614 CDS YP_899145.1 118498095 4548179 complement(1622245..1623663) 1 NC_008601.1 dihydrolipoamide dehydrogenase 1623663 4548179 FTN_1526 Francisella tularensis subsp. novicida U112 dihydrolipoamide dehydrogenase YP_899145.1 1622245 R 401614 CDS YP_899146.1 118498096 4548180 complement(1623666..1624385) 1 NC_008601.1 hypothetical protein 1624385 4548180 FTN_1527 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899146.1 1623666 R 401614 CDS YP_899147.1 118498097 4548181 1624415..1624978 1 NC_008601.1 methylated-DNA--protein-cysteine methyltransferase 1624978 4548181 FTN_1528 Francisella tularensis subsp. novicida U112 methylated-DNA--protein-cysteine methyltransferase YP_899147.1 1624415 D 401614 CDS YP_899148.1 118498098 4548182 complement(1625380..1626783) 1 NC_008601.1 APC family gamma-glutamate:GABA antiporter 1626783 4548182 FTN_1529 Francisella tularensis subsp. novicida U112 APC family gamma-glutamate:GABA antiporter YP_899148.1 1625380 R 401614 CDS YP_899149.1 118498099 4548183 complement(1626795..1627979) 1 NC_008601.1 diaminopimelate decarboxylase 1627979 lysA 4548183 lysA Francisella tularensis subsp. novicida U112 diaminopimelate decarboxylase YP_899149.1 1626795 R 401614 CDS YP_899150.1 118498100 4548184 complement(1627992..1628675) 1 NC_008601.1 hypothetical protein 1628675 4548184 FTN_1531 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899150.1 1627992 R 401614 CDS YP_899151.1 118498101 4548185 1629170..1630519 1 NC_008601.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1630519 gdhA 4548185 gdhA Francisella tularensis subsp. novicida U112 glutamate dehydrogenase YP_899151.1 1629170 D 401614 CDS YP_899152.1 118498102 4548186 1630614..1631804 1 NC_008601.1 hypothetical protein 1631804 4548186 FTN_1533 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899152.1 1630614 D 401614 CDS YP_899153.1 118498103 4548187 1631854..1632324 1 NC_008601.1 hypothetical protein 1632324 4548187 FTN_1534 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899153.1 1631854 D 401614 CDS YP_899154.1 118498104 4548897 1632461..1633285 1 NC_008601.1 short chain dehydrogenase 1633285 4548897 FTN_1535 Francisella tularensis subsp. novicida U112 short chain dehydrogenase YP_899154.1 1632461 D 401614 CDS YP_899155.1 118498105 4548898 complement(1633307..1634656) 1 NC_008601.1 amino acid-polyamine-organocation (APC) superfamily protein 1634656 4548898 FTN_1536 Francisella tularensis subsp. novicida U112 amino acid-polyamine-organocation (APC) superfamily protein YP_899155.1 1633307 R 401614 CDS YP_899156.1 118498106 4548899 complement(1635778..1636650) 1 NC_008601.1 hypothetical protein 1636650 4548899 FTN_1537 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899156.1 1635778 R 401614 CDS YP_899157.1 118498107 4548900 complement(1636881..1638515) 1 NC_008601.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 1638515 groEL 4548900 groEL Francisella tularensis subsp. novicida U112 chaperonin GroEL YP_899157.1 1636881 R 401614 CDS YP_899158.1 118498108 4548901 complement(1638553..1638840) 1 NC_008601.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 1638840 groES 4548901 groES Francisella tularensis subsp. novicida U112 co-chaperonin GroES YP_899158.1 1638553 R 401614 CDS YP_899159.1 118498109 4548902 1639091..1639525 1 NC_008601.1 hypothetical protein 1639525 4548902 FTN_1540 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899159.1 1639091 D 401614 CDS YP_899160.1 118498110 4548904 1640166..1640930 1 NC_008601.1 hypothetical protein 1640930 4548904 FTN_1542 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899160.1 1640166 D 401614 CDS YP_899161.1 118498111 4548905 1640934..1641401 1 NC_008601.1 hypothetical protein 1641401 4548905 FTN_1543 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899161.1 1640934 D 401614 CDS YP_899162.1 118498112 4548906 complement(1641392..1642246) 1 NC_008601.1 HemK family modification methylase 1642246 hemK 4548906 hemK Francisella tularensis subsp. novicida U112 HemK family modification methylase YP_899162.1 1641392 R 401614 CDS YP_899163.1 118498113 4548907 complement(1642239..1643324) 1 NC_008601.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1643324 prfA 4548907 prfA Francisella tularensis subsp. novicida U112 peptide chain release factor 1 YP_899163.1 1642239 R 401614 CDS YP_899164.1 118498114 4548908 complement(1643325..1644569) 1 NC_008601.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 1644569 hemA 4548908 hemA Francisella tularensis subsp. novicida U112 glutamyl-tRNA reductase YP_899164.1 1643325 R 401614 CDS YP_899165.1 118498115 4548909 1644749..1645387 1 NC_008601.1 hypothetical protein 1645387 4548909 FTN_1547 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899165.1 1644749 D 401614 CDS YP_899166.1 118498116 4548910 1645390..1646760 1 NC_008601.1 hypothetical protein 1646760 4548910 FTN_1548 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899166.1 1645390 D 401614 CDS YP_899167.1 118498117 4548911 1646760..1647941 1 NC_008601.1 drug:H+ antiporter-1 (DHA1) family protein 1647941 4548911 FTN_1549 Francisella tularensis subsp. novicida U112 drug:H+ antiporter-1 (DHA1) family protein YP_899167.1 1646760 D 401614 CDS YP_899168.1 118498118 4548912 1648031..1649914 1 NC_008601.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 1649914 parE 4548912 parE Francisella tularensis subsp. novicida U112 DNA topoisomerase IV subunit B YP_899168.1 1648031 D 401614 CDS YP_899169.1 118498119 4548913 complement(1649963..1650487) 1 NC_008601.1 N-acetyl-anhydromuranmyl-L-alanine amidase 1650487 ampD 4548913 ampD Francisella tularensis subsp. novicida U112 N-acetyl-anhydromuranmyl-L-alanine amidase YP_899169.1 1649963 R 401614 CDS YP_899170.1 118498120 4548914 1650561..1651187 1 NC_008601.1 acid phosphatase 1651187 4548914 FTN_1552 Francisella tularensis subsp. novicida U112 acid phosphatase YP_899170.1 1650561 D 401614 CDS YP_899171.1 118498121 4548439 complement(1651197..1651661) 1 NC_008601.1 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 1651661 nudH 4548439 nudH Francisella tularensis subsp. novicida U112 dinucleoside polyphosphate hydrolase YP_899171.1 1651197 R 401614 CDS YP_899172.1 118498122 4548440 1651824..1653344 1 NC_008601.1 hypothetical protein 1653344 4548440 FTN_1554 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899172.1 1651824 D 401614 CDS YP_899173.1 118498123 4548441 1653462..1654346 1 NC_008601.1 licB-like transmembrane protein 1654346 4548441 FTN_1555 Francisella tularensis subsp. novicida U112 licB-like transmembrane protein YP_899173.1 1653462 D 401614 CDS YP_899174.1 118498124 4548442 complement(1654343..1654927) 1 NC_008601.1 acid phosphatase 1654927 4548442 FTN_1556 Francisella tularensis subsp. novicida U112 acid phosphatase YP_899174.1 1654343 R 401614 CDS YP_899175.1 118498125 4548443 complement(1654932..1655777) 1 NC_008601.1 oxidoreductase iron/ascorbate family protein 1655777 4548443 FTN_1557 Francisella tularensis subsp. novicida U112 oxidoreductase iron/ascorbate family protein YP_899175.1 1654932 R 401614 CDS YP_899176.1 118498126 4548444 complement(1655900..1656778) 1 NC_008601.1 site-specific recombinase 1656778 xerD 4548444 xerD Francisella tularensis subsp. novicida U112 site-specific recombinase YP_899176.1 1655900 R 401614 CDS YP_899177.1 118498127 4548445 complement(1656944..1657291) 1 NC_008601.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1657291 rplS 4548445 rplS Francisella tularensis subsp. novicida U112 50S ribosomal protein L19 YP_899177.1 1656944 R 401614 CDS YP_899178.1 118498128 4548446 complement(1657291..1658049) 1 NC_008601.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1658049 trmD 4548446 trmD Francisella tularensis subsp. novicida U112 tRNA (guanine-N(1)-)-methyltransferase YP_899178.1 1657291 R 401614 CDS YP_899179.1 118498129 4548447 complement(1658454..1658963) 1 NC_008601.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1658963 rimM 4548447 rimM Francisella tularensis subsp. novicida U112 16S rRNA-processing protein RimM YP_899179.1 1658454 R 401614 CDS YP_899180.1 118498130 4548448 complement(1659007..1659255) 1 NC_008601.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1659255 rpsP 4548448 rpsP Francisella tularensis subsp. novicida U112 30S ribosomal protein S16 YP_899180.1 1659007 R 401614 CDS YP_899181.1 118498131 4548449 1659549..1660709 1 NC_008601.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 1660709 metK 4548449 metK Francisella tularensis subsp. novicida U112 S-adenosylmethionine synthetase YP_899181.1 1659549 D 401614 CDS YP_899182.1 118498132 4548450 complement(1660920..1662086) 1 NC_008601.1 fatty acid desaturase 1662086 4548450 FTN_1564 Francisella tularensis subsp. novicida U112 fatty acid desaturase YP_899182.1 1660920 R 401614 CDS YP_899183.1 118498133 4548451 complement(1662200..1663210) 1 NC_008601.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 1663210 gcp 4548451 gcp Francisella tularensis subsp. novicida U112 putative DNA-binding/iron metalloprotein/AP endonuclease YP_899183.1 1662200 R 401614 CDS YP_899184.1 118498134 4548452 complement(1663210..1663446) 1 NC_008601.1 hypothetical protein 1663446 4548452 FTN_1566 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899184.1 1663210 R 401614 CDS YP_899185.1 118498135 4548453 complement(1663549..1667802) 1 NC_008601.1 DNA-directed RNA polymerase, beta' subunit/160 kD subunit 1667802 rpoC 4548453 rpoC Francisella tularensis subsp. novicida U112 DNA-directed RNA polymerase, beta' subunit/160 kD subunit YP_899185.1 1663549 R 401614 CDS YP_899186.1 118498136 4548454 complement(1667864..1671940) 1 NC_008601.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 1671940 rpoB 4548454 rpoB Francisella tularensis subsp. novicida U112 DNA-directed RNA polymerase subunit beta YP_899186.1 1667864 R 401614 CDS YP_899187.1 118498137 4548455 complement(1672094..1672471) 1 NC_008601.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 1672471 rplL 4548455 rplL Francisella tularensis subsp. novicida U112 50S ribosomal protein L7/L12 YP_899187.1 1672094 R 401614 CDS YP_899188.1 118498138 4548456 complement(1672534..1673052) 1 NC_008601.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 1673052 rplJ 4548456 rplJ Francisella tularensis subsp. novicida U112 50S ribosomal protein L10 YP_899188.1 1672534 R 401614 CDS YP_899189.1 118498139 4548457 complement(1673222..1673917) 1 NC_008601.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 1673917 rplA 4548457 rplA Francisella tularensis subsp. novicida U112 50S ribosomal protein L1 YP_899189.1 1673222 R 401614 CDS YP_899190.1 118498140 4548915 complement(1673920..1674354) 1 NC_008601.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 1674354 rplK 4548915 rplK Francisella tularensis subsp. novicida U112 50S ribosomal protein L11 YP_899190.1 1673920 R 401614 CDS YP_899191.1 118498141 4548916 complement(1674423..1674956) 1 NC_008601.1 transcription antitermination protein nusG 1674956 nusG 4548916 nusG Francisella tularensis subsp. novicida U112 transcription antitermination protein nusG YP_899191.1 1674423 R 401614 CDS YP_899192.1 118498142 4548917 complement(1674972..1675442) 1 NC_008601.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 1675442 secE 4548917 secE Francisella tularensis subsp. novicida U112 preprotein translocase subunit SecE YP_899192.1 1674972 R 401614 CDS YP_899193.1 118498143 4548919 complement(1675634..1676818) 1 NC_008601.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 1676818 tufA 4548919 tufA Francisella tularensis subsp. novicida U112 elongation factor Tu YP_899193.1 1675634 R 401614 CDS YP_899194.1 118498144 4548923 complement(1677283..1678698) 1 NC_008601.1 DNA helicase 1678698 4548923 FTN_1580 Francisella tularensis subsp. novicida U112 DNA helicase YP_899194.1 1677283 R 401614 CDS YP_899195.1 118498145 4548924 complement(1678698..1679195) 1 NC_008601.1 small conductance mechanosensitive ion channel (MscS) family protein 1679195 4548924 FTN_1581 Francisella tularensis subsp. novicida U112 small conductance mechanosensitive ion channel (MscS) family protein YP_899195.1 1678698 R 401614 CDS YP_899196.1 118498146 4548925 complement(1679173..1679886) 1 NC_008601.1 hypothetical protein 1679886 4548925 FTN_1582 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899196.1 1679173 R 401614 CDS YP_899197.1 118498147 4548926 complement(1679890..1680654) 1 NC_008601.1 glycerol uptake facilitator protein 1680654 glpF 4548926 glpF Francisella tularensis subsp. novicida U112 glycerol uptake facilitator protein YP_899197.1 1679890 R 401614 CDS YP_899198.1 118498148 4548927 complement(1680664..1682196) 1 NC_008601.1 glycerol-3-phosphate dehydrogenase 1682196 glpD 4548927 glpD Francisella tularensis subsp. novicida U112 glycerol-3-phosphate dehydrogenase YP_899198.1 1680664 R 401614 CDS YP_899199.1 118498149 4548928 complement(1682445..1683947) 1 NC_008601.1 glycerol kinase 1683947 glpK 4548928 glpK Francisella tularensis subsp. novicida U112 glycerol kinase YP_899199.1 1682445 R 401614 CDS YP_899200.1 118498150 4548929 complement(1684004..1685317) 1 NC_008601.1 major facilitator superfamily sugar transporter 1685317 4548929 FTN_1586 Francisella tularensis subsp. novicida U112 major facilitator superfamily sugar transporter YP_899200.1 1684004 R 401614 CDS YP_899201.1 118498151 4548877 complement(1685387..1685998) 1 NC_008601.1 hypothetical protein 1685998 4548877 FTN_1587 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899201.1 1685387 R 401614 CDS YP_899202.1 118498152 4548878 1686132..1687334 1 NC_008601.1 major facilitator transporter 1687334 4548878 FTN_1588 Francisella tularensis subsp. novicida U112 major facilitator transporter YP_899202.1 1686132 D 401614 CDS YP_899203.1 118498153 4548879 complement(1687338..1688312) 1 NC_008601.1 peptide/opine/nickel uptake transporter (PepT) family protein 1688312 oppF 4548879 oppF Francisella tularensis subsp. novicida U112 peptide/opine/nickel uptake transporter (PepT) family protein YP_899203.1 1687338 R 401614 CDS YP_899204.1 118498154 4548880 complement(1688313..1689281) 1 NC_008601.1 peptide/opine/nickel uptake transporter (PepT) family protein 1689281 oppD 4548880 oppD Francisella tularensis subsp. novicida U112 peptide/opine/nickel uptake transporter (PepT) family protein YP_899204.1 1688313 R 401614 CDS YP_899205.1 118498155 4548881 complement(1689285..1690145) 1 NC_008601.1 peptide/opine/nickel uptake transporter (PepT) family protein 1690145 oppC 4548881 oppC Francisella tularensis subsp. novicida U112 peptide/opine/nickel uptake transporter (PepT) family protein YP_899205.1 1689285 R 401614 CDS YP_899206.1 118498156 4548882 complement(1690145..1691083) 1 NC_008601.1 peptide/opine/nickel uptake transporter (PepT) family protein 1691083 oppB 4548882 oppB Francisella tularensis subsp. novicida U112 peptide/opine/nickel uptake transporter (PepT) family protein YP_899206.1 1690145 R 401614 CDS YP_899207.1 118498157 4548883 complement(1691108..1692784) 1 NC_008601.1 oligopeptide ABC transporter periplasmic protein 1692784 oppA 4548883 oppA Francisella tularensis subsp. novicida U112 oligopeptide ABC transporter periplasmic protein YP_899207.1 1691108 R 401614 CDS YP_899208.1 118498158 4548884 complement(1692874..1695096) 1 NC_008601.1 DNA helicase II 1695096 uvrD 4548884 uvrD Francisella tularensis subsp. novicida U112 DNA helicase II YP_899208.1 1692874 R 401614 CDS YP_899209.1 118498159 4548885 complement(1695187..1696182) 1 NC_008601.1 cell division protein, signal recognition particle GTPase 1696182 ftsY 4548885 ftsY Francisella tularensis subsp. novicida U112 cell division protein, signal recognition particle GTPase YP_899209.1 1695187 R 401614 CDS YP_899210.1 118498160 4548886 complement(1696215..1697531) 1 NC_008601.1 Type IV pili, pilus assembly protein 1697531 fimV 4548886 fimV Francisella tularensis subsp. novicida U112 Type IV pili, pilus assembly protein YP_899210.1 1696215 R 401614 CDS YP_899211.1 118498161 4548887 complement(1697606..1699183) 1 NC_008601.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 1699183 prfC 4548887 prfC Francisella tularensis subsp. novicida U112 peptide chain release factor 3 YP_899211.1 1697606 R 401614 CDS YP_899212.1 118498162 4548888 complement(1699245..1699874) 1 NC_008601.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 1699874 tmk 4548888 tmk Francisella tularensis subsp. novicida U112 thymidylate kinase YP_899212.1 1699245 R 401614 CDS YP_899213.1 118498163 4548889 complement(1699887..1701089) 1 NC_008601.1 nucleoside permease NUP family protein 1701089 nupC 4548889 nupC Francisella tularensis subsp. novicida U112 nucleoside permease NUP family protein YP_899213.1 1699887 R 401614 CDS YP_899214.1 118498164 4548890 complement(1701108..1702307) 1 NC_008601.1 nucleoside permease NUP family protein 1702307 nupC1 4548890 nupC1 Francisella tularensis subsp. novicida U112 nucleoside permease NUP family protein YP_899214.1 1701108 R 401614 CDS YP_899215.1 118498165 4548891 complement(1702297..1703058) 1 NC_008601.1 deoxyribose-phosphate aldolase 1703058 deoC 4548891 deoC Francisella tularensis subsp. novicida U112 deoxyribose-phosphate aldolase YP_899215.1 1702297 R 401614 CDS YP_899216.1 118498166 4548892 complement(1703021..1704265) 1 NC_008601.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 1704265 deoB 4548892 deoB Francisella tularensis subsp. novicida U112 phosphopentomutase YP_899216.1 1703021 R 401614 CDS YP_899217.1 118498167 4548893 complement(1704270..1705046) 1 NC_008601.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase 1705046 4548893 FTN_1603 Francisella tularensis subsp. novicida U112 pantothenate kinase YP_899217.1 1704270 R 401614 CDS YP_899218.1 118498168 4548894 complement(1705066..1707759) 1 NC_008601.1 DNA polymerase I 1707759 polA 4548894 polA Francisella tularensis subsp. novicida U112 DNA polymerase I YP_899218.1 1705066 R 401614 CDS YP_899219.1 118498169 4548895 complement(1707855..1708823) 1 NC_008601.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 1708823 lpxK 4548895 lpxK Francisella tularensis subsp. novicida U112 tetraacyldisaccharide 4'-kinase YP_899219.1 1707855 R 401614 CDS YP_899220.1 118498170 4548896 complement(1708829..1710658) 1 NC_008601.1 lipid exporter (LipidE) family protein 1710658 msbA 4548896 msbA Francisella tularensis subsp. novicida U112 lipid exporter (LipidE) family protein YP_899220.1 1708829 R 401614 CDS YP_899221.1 118498171 4547209 1710763..1711872 1 NC_008601.1 catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity; tRNA CCA-pyrophosphorylase 1711872 cca 4547209 cca Francisella tularensis subsp. novicida U112 tRNA CCA-pyrophosphorylase YP_899221.1 1710763 D 401614 CDS YP_899222.1 118498172 4547210 1711912..1712403 1 NC_008601.1 disulfide bond formation protein 1712403 dsbB 4547210 dsbB Francisella tularensis subsp. novicida U112 disulfide bond formation protein YP_899222.1 1711912 D 401614 CDS YP_899223.1 118498173 4547211 1712416..1713789 1 NC_008601.1 membrane fusion protein 1713789 4547211 FTN_1609 Francisella tularensis subsp. novicida U112 membrane fusion protein YP_899223.1 1712416 D 401614 CDS YP_899224.1 118498174 4547212 1713789..1716902 1 NC_008601.1 RND efflux transporter 1716902 4547212 FTN_1610 Francisella tularensis subsp. novicida U112 RND efflux transporter YP_899224.1 1713789 D 401614 CDS YP_899225.1 118498175 4547213 1717771..1719051 1 NC_008601.1 major facilitator transporter 1719051 4547213 FTN_1611 Francisella tularensis subsp. novicida U112 major facilitator transporter YP_899225.1 1717771 D 401614 CDS YP_899226.1 118498176 4547214 1719296..1719877 1 NC_008601.1 hypothetical protein 1719877 4547214 FTN_1612 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899226.1 1719296 D 401614 CDS YP_899227.1 118498177 4547215 complement(1720107..1721120) 1 NC_008601.1 U61 family peptidase 1721120 4547215 FTN_1613 Francisella tularensis subsp. novicida U112 U61 family peptidase YP_899227.1 1720107 R 401614 CDS YP_899228.1 118498178 4547217 complement(1724058..1725338) 1 NC_008601.1 hypothetical protein 1725338 4547217 FTN_1615 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899228.1 1724058 R 401614 CDS YP_899229.1 118498179 4547218 complement(1725342..1726298) 1 NC_008601.1 hypothetical protein 1726298 4547218 FTN_1616 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899229.1 1725342 R 401614 CDS YP_899230.1 118498180 4547219 1726414..1727841 1 NC_008601.1 two-component regulator, sensor histidine kinase 1727841 4547219 FTN_1617 Francisella tularensis subsp. novicida U112 two-component regulator, sensor histidine kinase YP_899230.1 1726414 D 401614 CDS YP_899231.1 118498181 4547220 complement(1727838..1728719) 1 NC_008601.1 hypothetical protein 1728719 4547220 FTN_1618 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899231.1 1727838 R 401614 CDS YP_899232.1 118498182 4547221 1728955..1730331 1 NC_008601.1 cytochrome bd-II terminal oxidase subunit I 1730331 appC 4547221 appC Francisella tularensis subsp. novicida U112 cytochrome bd-II terminal oxidase subunit I YP_899232.1 1728955 D 401614 CDS YP_899233.1 118498183 4547222 1730335..1731297 1 NC_008601.1 cytochrome bd-II terminal oxidase subunit II 1731297 appB 4547222 appB Francisella tularensis subsp. novicida U112 cytochrome bd-II terminal oxidase subunit II YP_899233.1 1730335 D 401614 CDS YP_899234.1 118498184 4547223 1731751..1732737 1 NC_008601.1 NAD/FAD-dependent oxidoreductase 1732737 4547223 FTN_1621 Francisella tularensis subsp. novicida U112 NAD/FAD-dependent oxidoreductase YP_899234.1 1731751 D 401614 CDS YP_899235.1 118498185 4548001 complement(1732817..1733845) 1 NC_008601.1 Type IV pili nucleotide-binding protein 1733845 pilT 4548001 pilT Francisella tularensis subsp. novicida U112 Type IV pili nucleotide-binding protein YP_899235.1 1732817 R 401614 CDS YP_899236.1 118498186 4548002 complement(1733940..1736753) 1 NC_008601.1 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1736753 acnA 4548002 acnA Francisella tularensis subsp. novicida U112 aconitate hydratase YP_899236.1 1733940 R 401614 CDS YP_899237.1 118498187 4548003 complement(1736858..1737736) 1 NC_008601.1 hypothetical protein 1737736 4548003 FTN_1624 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899237.1 1736858 R 401614 CDS YP_899238.1 118498188 4548004 1737806..1738183 1 NC_008601.1 hypothetical protein 1738183 4548004 FTN_1625 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899238.1 1737806 D 401614 CDS YP_899239.1 118498189 4548005 1738188..1739330 1 NC_008601.1 coproporphyrinogen III oxidase, anaerobic 1739330 hemN 4548005 hemN Francisella tularensis subsp. novicida U112 coproporphyrinogen III oxidase, anaerobic YP_899239.1 1738188 D 401614 CDS YP_899240.1 118498190 4548006 complement(1739327..1739779) 1 NC_008601.1 hypothetical protein 1739779 4548006 FTN_1627 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899240.1 1739327 R 401614 CDS YP_899241.1 118498191 4548007 complement(1739838..1740791) 1 NC_008601.1 LysR family transcriptional regulator 1740791 4548007 FTN_1628 Francisella tularensis subsp. novicida U112 LysR family transcriptional regulator YP_899241.1 1739838 R 401614 CDS YP_899242.1 118498192 4548009 complement(1740961..1741314) 1 NC_008601.1 preprotein translocase subunit SecG 1741314 secG 4548009 secG Francisella tularensis subsp. novicida U112 preprotein translocase subunit SecG YP_899242.1 1740961 R 401614 CDS YP_899243.1 118498193 4548010 complement(1741302..1742063) 1 NC_008601.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 1742063 tpiA 4548010 tpiA Francisella tularensis subsp. novicida U112 triosephosphate isomerase YP_899243.1 1741302 R 401614 CDS YP_899244.1 118498194 4548011 complement(1742066..1743397) 1 NC_008601.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 1743397 glmM 4548011 glmM Francisella tularensis subsp. novicida U112 phosphoglucosamine mutase YP_899244.1 1742066 R 401614 CDS YP_899245.1 118498195 4548012 complement(1743408..1743935) 1 NC_008601.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 1743935 apt 4548012 apt Francisella tularensis subsp. novicida U112 adenine phosphoribosyltransferase YP_899245.1 1743408 R 401614 CDS YP_899246.1 118498196 4548013 complement(1743975..1745444) 1 NC_008601.1 2-oxoglutarate dehydrogenase complex, E2 component, dihydrolipoyltranssuccinase 1745444 sucB 4548013 sucB Francisella tularensis subsp. novicida U112 2-oxoglutarate dehydrogenase complex, E2 component, dihydrolipoyltranssuccinase YP_899246.1 1743975 R 401614 CDS YP_899247.1 118498197 4548014 complement(1745470..1748283) 1 NC_008601.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 1748283 sucA 4548014 sucA Francisella tularensis subsp. novicida U112 2-oxoglutarate dehydrogenase E1 component YP_899247.1 1745470 R 401614 CDS YP_899248.1 118498198 4548015 complement(1748313..1749014) 1 NC_008601.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 1749014 sdhB 4548015 sdhB Francisella tularensis subsp. novicida U112 succinate dehydrogenase iron-sulfur subunit YP_899248.1 1748313 R 401614 CDS YP_899249.1 118498199 4548016 complement(1749032..1750825) 1 NC_008601.1 succinate dehydrogenase flavoprotein 1750825 sdhA 4548016 sdhA Francisella tularensis subsp. novicida U112 succinate dehydrogenase flavoprotein YP_899249.1 1749032 R 401614 CDS YP_899250.1 118498200 4548017 complement(1750838..1751206) 1 NC_008601.1 succinate dehydrogenase hydrophobic membrane anchor protein 1751206 sdhD 4548017 sdhD Francisella tularensis subsp. novicida U112 succinate dehydrogenase hydrophobic membrane anchor protein YP_899250.1 1750838 R 401614 CDS YP_899251.1 118498201 4548018 complement(1751182..1751655) 1 NC_008601.1 succinate dehydrogenase, cytochrome b556 1751655 sdhC 4548018 sdhC Francisella tularensis subsp. novicida U112 succinate dehydrogenase, cytochrome b556 YP_899251.1 1751182 R 401614 CDS YP_899252.1 118498202 4548019 1751913..1753172 1 NC_008601.1 citrate synthase 1753172 gltA 4548019 gltA Francisella tularensis subsp. novicida U112 citrate synthase YP_899252.1 1751913 D 401614 CDS YP_899253.1 118498203 4548020 1753261..1754526 1 NC_008601.1 major facilitator transporter 1754526 ampG 4548020 ampG Francisella tularensis subsp. novicida U112 major facilitator transporter YP_899253.1 1753261 D 401614 CDS YP_899254.1 118498204 4548021 complement(1754731..1755309) 1 NC_008601.1 iron/manganese superoxide dismutase family protein 1755309 sodB 4548021 sodB Francisella tularensis subsp. novicida U112 iron/manganese superoxide dismutase family protein YP_899254.1 1754731 R 401614 CDS YP_899255.1 118498205 4548022 1755445..1755774 1 NC_008601.1 glutaredoxin-like protein 1755774 4548022 FTN_1643 Francisella tularensis subsp. novicida U112 glutaredoxin-like protein YP_899255.1 1755445 D 401614 CDS YP_899256.1 118498206 4548023 complement(1755791..1758634) 1 NC_008601.1 hypothetical protein 1758634 4548023 FTN_1644 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899256.1 1755791 R 401614 CDS YP_899257.1 118498207 4548024 complement(1759707..1760144) 1 NC_008601.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the epsilon subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit epsilon 1760144 atpC 4548024 atpC Francisella tularensis subsp. novicida U112 F0F1 ATP synthase subunit epsilon YP_899257.1 1759707 R 401614 CDS YP_899258.1 118498208 4548025 complement(1760157..1761533) 1 NC_008601.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 1761533 atpD 4548025 atpD Francisella tularensis subsp. novicida U112 F0F1 ATP synthase subunit beta YP_899258.1 1760157 R 401614 CDS YP_899259.1 118498209 4548026 complement(1761543..1762439) 1 NC_008601.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 1762439 atpG 4548026 atpG Francisella tularensis subsp. novicida U112 F0F1 ATP synthase subunit gamma YP_899259.1 1761543 R 401614 CDS YP_899260.1 118498210 4548027 complement(1762454..1763995) 1 NC_008601.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 1763995 atpA 4548027 atpA Francisella tularensis subsp. novicida U112 F0F1 ATP synthase subunit alpha YP_899260.1 1762454 R 401614 CDS YP_899261.1 118498211 4548028 complement(1764014..1764538) 1 NC_008601.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 1764538 atpH 4548028 atpH Francisella tularensis subsp. novicida U112 F0F1 ATP synthase subunit delta YP_899261.1 1764014 R 401614 CDS YP_899262.1 118498212 4548029 complement(1764558..1765028) 1 NC_008601.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 1765028 atpF 4548029 atpF Francisella tularensis subsp. novicida U112 F0F1 ATP synthase subunit B YP_899262.1 1764558 R 401614 CDS YP_899263.1 118498213 4548030 complement(1765074..1765379) 1 NC_008601.1 produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 1765379 atpE 4548030 atpE Francisella tularensis subsp. novicida U112 F0F1 ATP synthase subunit C YP_899263.1 1765074 R 401614 CDS YP_899264.1 118498214 4548031 complement(1765430..1766221) 1 NC_008601.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 1766221 atpB 4548031 atpB Francisella tularensis subsp. novicida U112 F0F1 ATP synthase subunit A YP_899264.1 1765430 R 401614 CDS YP_899265.1 118498215 4548032 complement(1766274..1766705) 1 NC_008601.1 hypothetical protein 1766705 4548032 FTN_1653 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899265.1 1766274 R 401614 CDS YP_899266.1 118498216 4548033 1766782..1768086 1 NC_008601.1 major facilitator transporter 1768086 4548033 FTN_1654 Francisella tularensis subsp. novicida U112 major facilitator transporter YP_899266.1 1766782 D 401614 CDS YP_899267.1 118498217 4548034 complement(1768088..1769017) 1 NC_008601.1 ribosomal large subunit pseudouridine synthase C 1769017 rluC 4548034 rluC Francisella tularensis subsp. novicida U112 ribosomal large subunit pseudouridine synthase C YP_899267.1 1768088 R 401614 CDS YP_899268.1 118498218 4548035 complement(1769010..1770077) 1 NC_008601.1 ATPase 1770077 4548035 FTN_1656 Francisella tularensis subsp. novicida U112 ATPase YP_899268.1 1769010 R 401614 CDS YP_899269.1 118498219 4548036 complement(1770080..1771378) 1 NC_008601.1 major facilitator transporter 1771378 4548036 FTN_1657 Francisella tularensis subsp. novicida U112 major facilitator transporter YP_899269.1 1770080 R 401614 CDS YP_899270.1 118498220 4548037 complement(1771385..1772650) 1 NC_008601.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 1772650 hisS 4548037 hisS Francisella tularensis subsp. novicida U112 histidyl-tRNA synthetase YP_899270.1 1771385 R 401614 CDS YP_899271.1 118498221 4548839 complement(1772658..1773089) 1 NC_008601.1 ribosome-binding factor A 1773089 rbfA 4548839 rbfA Francisella tularensis subsp. novicida U112 ribosome-binding factor A YP_899271.1 1772658 R 401614 CDS YP_899272.1 118498222 4548840 complement(1773092..1775632) 1 NC_008601.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 1775632 infB 4548840 infB Francisella tularensis subsp. novicida U112 translation initiation factor IF-2 YP_899272.1 1773092 R 401614 CDS YP_899273.1 118498223 4548841 complement(1775671..1777140) 1 NC_008601.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 1777140 nusA 4548841 nusA Francisella tularensis subsp. novicida U112 transcription elongation factor NusA YP_899273.1 1775671 R 401614 CDS YP_899274.1 118498224 4548842 complement(1777158..1777610) 1 NC_008601.1 hypothetical protein 1777610 4548842 FTN_1662 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899274.1 1777158 R 401614 CDS YP_899275.1 118498225 4548844 complement(1777836..1778870) 1 NC_008601.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 1778870 hemE 4548844 hemE Francisella tularensis subsp. novicida U112 uroporphyrinogen decarboxylase YP_899275.1 1777836 R 401614 CDS YP_899276.1 118498226 4548845 complement(1778924..1780432) 1 NC_008601.1 magnesium chelatase 1780432 4548845 FTN_1665 Francisella tularensis subsp. novicida U112 magnesium chelatase YP_899276.1 1778924 R 401614 CDS YP_899277.1 118498227 4548846 complement(1780434..1780628) 1 NC_008601.1 hypothetical protein 1780628 4548846 FTN_1666 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899277.1 1780434 R 401614 CDS YP_899278.1 118498228 4548847 complement(1780704..1782155) 1 NC_008601.1 NADH dehydrogenase I subunit N 1782155 nuoN 4548847 nuoN Francisella tularensis subsp. novicida U112 NADH dehydrogenase I subunit N YP_899278.1 1780704 R 401614 CDS YP_899279.1 118498229 4548848 complement(1782171..1783760) 1 NC_008601.1 NADH dehydrogenase I subunit M 1783760 nuoM 4548848 nuoM Francisella tularensis subsp. novicida U112 NADH dehydrogenase I subunit M YP_899279.1 1782171 R 401614 CDS YP_899280.1 118498230 4548849 complement(1783786..1785795) 1 NC_008601.1 NADH dehydrogenase I subunit L 1785795 nuoL 4548849 nuoL Francisella tularensis subsp. novicida U112 NADH dehydrogenase I subunit L YP_899280.1 1783786 R 401614 CDS YP_899281.1 118498231 4548850 complement(1785805..1786122) 1 NC_008601.1 NADH dehydrogenase I subunit K 1786122 nuoK 4548850 nuoK Francisella tularensis subsp. novicida U112 NADH dehydrogenase I subunit K YP_899281.1 1785805 R 401614 CDS YP_899282.1 118498232 4548851 complement(1786115..1786720) 1 NC_008601.1 NADH dehydrogenase I subunit J 1786720 nuoJ 4548851 nuoJ Francisella tularensis subsp. novicida U112 NADH dehydrogenase I subunit J YP_899282.1 1786115 R 401614 CDS YP_899283.1 118498233 4548852 complement(1786725..1787213) 1 NC_008601.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 1787213 nuoI 4548852 nuoI Francisella tularensis subsp. novicida U112 NADH dehydrogenase subunit I YP_899283.1 1786725 R 401614 CDS YP_899284.1 118498234 4548853 complement(1787227..1788237) 1 NC_008601.1 NADH dehydrogenase I subunit H 1788237 nuoH 4548853 nuoH Francisella tularensis subsp. novicida U112 NADH dehydrogenase I subunit H YP_899284.1 1787227 R 401614 CDS YP_899285.1 118498235 4548854 complement(1788239..1790605) 1 NC_008601.1 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit G 1790605 nuoG 4548854 nuoG Francisella tularensis subsp. novicida U112 NADH dehydrogenase subunit G YP_899285.1 1788239 R 401614 CDS YP_899286.1 118498236 4548855 complement(1790623..1791897) 1 NC_008601.1 NADH dehydrogenase I subunit F 1791897 nuoF 4548855 nuoF Francisella tularensis subsp. novicida U112 NADH dehydrogenase I subunit F YP_899286.1 1790623 R 401614 CDS YP_899287.1 118498237 4548856 complement(1791904..1792392) 1 NC_008601.1 NADH dehydrogenase I subunit E 1792392 nuoE 4548856 nuoE Francisella tularensis subsp. novicida U112 NADH dehydrogenase I subunit E YP_899287.1 1791904 R 401614 CDS YP_899288.1 118498238 4548857 complement(1792402..1793655) 1 NC_008601.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 1793655 nuoD 4548857 nuoD Francisella tularensis subsp. novicida U112 NADH dehydrogenase subunit D YP_899288.1 1792402 R 401614 CDS YP_899289.1 118498239 4548858 complement(1793677..1794321) 1 NC_008601.1 NADH dehydrogenase I subunit C 1794321 nuoC 4548858 nuoC Francisella tularensis subsp. novicida U112 NADH dehydrogenase I subunit C YP_899289.1 1793677 R 401614 CDS YP_899290.1 118498240 4548859 complement(1794324..1794800) 1 NC_008601.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 1794800 nuoB 4548859 nuoB Francisella tularensis subsp. novicida U112 NADH dehydrogenase subunit B YP_899290.1 1794324 R 401614 CDS YP_899291.1 118498241 4548860 complement(1794791..1795189) 1 NC_008601.1 NADH dehydrogenase I subunit A 1795189 nuoA 4548860 nuoA Francisella tularensis subsp. novicida U112 NADH dehydrogenase I subunit A YP_899291.1 1794791 R 401614 CDS YP_899292.1 118498242 4548861 1795398..1795820 1 NC_008601.1 ferric uptake regulation protein 1795820 fur 4548861 fur Francisella tularensis subsp. novicida U112 ferric uptake regulation protein YP_899292.1 1795398 D 401614 CDS YP_899293.1 118498243 4548862 1796074..1797993 1 NC_008601.1 siderophore biosynthesis protein 1797993 frgA 4548862 frgA Francisella tularensis subsp. novicida U112 siderophore biosynthesis protein YP_899293.1 1796074 D 401614 CDS YP_899294.1 118498244 4548863 1798000..1799262 1 NC_008601.1 drug:H+ antiporter-1 (DHA1) family protein 1799262 4548863 FTN_1683 Francisella tularensis subsp. novicida U112 drug:H+ antiporter-1 (DHA1) family protein YP_899294.1 1798000 D 401614 CDS YP_899295.1 118498245 4548864 1799255..1800508 1 NC_008601.1 diaminopimelate decarboxylase 1800508 4548864 FTN_1684 Francisella tularensis subsp. novicida U112 diaminopimelate decarboxylase YP_899295.1 1799255 D 401614 CDS YP_899296.1 118498246 4548865 1800523..1801713 1 NC_008601.1 drug:H+ antiporter-1 (DHA1) family protein 1801713 4548865 FTN_1685 Francisella tularensis subsp. novicida U112 drug:H+ antiporter-1 (DHA1) family protein YP_899296.1 1800523 D 401614 CDS YP_899297.1 118498247 4548866 1801799..1803328 1 NC_008601.1 hypothetical protein 1803328 4548866 FTN_1686 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899297.1 1801799 D 401614 CDS YP_899298.1 118498248 4548867 1803376..1804869 1 NC_008601.1 GDSL-like lipolytic enzyme 1804869 4548867 FTN_1687 Francisella tularensis subsp. novicida U112 GDSL-like lipolytic enzyme YP_899298.1 1803376 D 401614 CDS YP_899299.1 118498249 4548868 complement(1804885..1805292) 1 NC_008601.1 hypothetical protein 1805292 4548868 FTN_1688 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899299.1 1804885 R 401614 CDS YP_899300.1 118498250 4548869 complement(1805307..1806728) 1 NC_008601.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 1806728 gatB 4548869 gatB Francisella tularensis subsp. novicida U112 aspartyl/glutamyl-tRNA amidotransferase subunit B YP_899300.1 1805307 R 401614 CDS YP_899301.1 118498251 4548870 complement(1806731..1808176) 1 NC_008601.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 1808176 gatA 4548870 gatA Francisella tularensis subsp. novicida U112 aspartyl/glutamyl-tRNA amidotransferase subunit A YP_899301.1 1806731 R 401614 CDS YP_899302.1 118498252 4548871 complement(1808185..1808466) 1 NC_008601.1 Glu-tRNAGln amidotransferase C subunit 1808466 gatC 4548871 gatC Francisella tularensis subsp. novicida U112 Glu-tRNAGln amidotransferase C subunit YP_899302.1 1808185 R 401614 CDS YP_899303.1 118498253 4548872 complement(1808549..1809619) 1 NC_008601.1 membrane fusion protein 1809619 4548872 FTN_1692 Francisella tularensis subsp. novicida U112 membrane fusion protein YP_899303.1 1808549 R 401614 CDS YP_899304.1 118498254 4548873 complement(1809630..1811171) 1 NC_008601.1 ATP-binding cassette (ABC) superfamily protein 1811171 4548873 FTN_1693 Francisella tularensis subsp. novicida U112 ATP-binding cassette (ABC) superfamily protein YP_899304.1 1809630 R 401614 CDS YP_899305.1 118498255 4548874 complement(1811327..1812625) 1 NC_008601.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 1812625 purB 4548874 purB Francisella tularensis subsp. novicida U112 adenylosuccinate lyase YP_899305.1 1811327 R 401614 CDS YP_899306.1 118498256 4548875 1812953..1813588 1 NC_008601.1 hypothetical protein 1813588 4548875 FTN_1695 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899306.1 1812953 D 401614 CDS YP_899307.1 118498257 4548876 1813595..1814377 1 NC_008601.1 hypothetical protein 1814377 4548876 FTN_1696 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899307.1 1813595 D 401614 CDS YP_899308.1 118498258 4548575 complement(1814403..1815263) 1 NC_008601.1 galactose mutarotase 1815263 4548575 FTN_1697 Francisella tularensis subsp. novicida U112 galactose mutarotase YP_899308.1 1814403 R 401614 CDS YP_899309.1 118498259 4548576 complement(1815849..1816619) 1 NC_008601.1 Dam-replacing family protein 1816619 4548576 FTN_1698 Francisella tularensis subsp. novicida U112 Dam-replacing family protein YP_899309.1 1815849 R 401614 CDS YP_899310.1 118498260 4548577 complement(1816647..1820534) 1 NC_008601.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 1820534 purL 4548577 purL Francisella tularensis subsp. novicida U112 phosphoribosylformylglycinamidine synthase YP_899310.1 1816647 R 401614 CDS YP_899311.1 118498261 4548578 complement(1820534..1822024) 1 NC_008601.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 1822024 purF 4548578 purF Francisella tularensis subsp. novicida U112 amidophosphoribosyltransferase YP_899311.1 1820534 R 401614 CDS YP_899312.1 118498262 4548579 complement(1822118..1823464) 1 NC_008601.1 glutamate decarboxylase 1823464 4548579 FTN_1701 Francisella tularensis subsp. novicida U112 glutamate decarboxylase YP_899312.1 1822118 R 401614 CDS YP_899313.1 118498263 4548580 complement(1823475..1824116) 1 NC_008601.1 phosphopantetheinyl transferase 1824116 4548580 FTN_1702 Francisella tularensis subsp. novicida U112 phosphopantetheinyl transferase YP_899313.1 1823475 R 401614 CDS YP_899314.1 118498264 4548581 complement(1824125..1825654) 1 NC_008601.1 outer membrane protein tolC 1825654 tolC 4548581 tolC Francisella tularensis subsp. novicida U112 outer membrane protein tolC YP_899314.1 1824125 R 401614 CDS YP_899315.1 118498265 4548582 complement(1825663..1826283) 1 NC_008601.1 protein-L-isoaspartate O-methyltransferase 1826283 pcm 4548582 pcm Francisella tularensis subsp. novicida U112 protein-L-isoaspartate O-methyltransferase YP_899315.1 1825663 R 401614 CDS YP_899316.1 118498266 4548583 1826603..1827934 1 NC_008601.1 U32 family peptidase 1827934 4548583 FTN_1705 Francisella tularensis subsp. novicida U112 U32 family peptidase YP_899316.1 1826603 D 401614 CDS YP_899317.1 118498267 4548584 complement(1827976..1829157) 1 NC_008601.1 drug:H+ antiporter-1 (DHA1) family protein 1829157 4548584 FTN_1706 Francisella tularensis subsp. novicida U112 drug:H+ antiporter-1 (DHA1) family protein YP_899317.1 1827976 R 401614 CDS YP_899318.1 118498268 4548585 1829332..1830759 1 NC_008601.1 Na+/H+ antiporter 1830759 nhaD 4548585 nhaD Francisella tularensis subsp. novicida U112 Na+/H+ antiporter YP_899318.1 1829332 D 401614 CDS YP_899319.1 118498269 4548586 complement(1830749..1832410) 1 NC_008601.1 ATP-binding cassette (ABC) superfamily protein 1832410 4548586 FTN_1708 Francisella tularensis subsp. novicida U112 ATP-binding cassette (ABC) superfamily protein YP_899319.1 1830749 R 401614 CDS YP_899320.1 118498270 4548587 complement(1832411..1834285) 1 NC_008601.1 amino acid transporter 1834285 4548587 FTN_1709 Francisella tularensis subsp. novicida U112 amino acid transporter YP_899320.1 1832411 R 401614 CDS YP_899321.1 118498271 4548588 complement(1834292..1835296) 1 NC_008601.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 1835296 obgE 4548588 obgE Francisella tularensis subsp. novicida U112 GTPase ObgE YP_899321.1 1834292 R 401614 CDS YP_899322.1 118498272 4548589 complement(1835369..1836565) 1 NC_008601.1 tyrosine permease 1836565 tyrP 4548589 tyrP Francisella tularensis subsp. novicida U112 tyrosine permease YP_899322.1 1835369 R 401614 CDS YP_899323.1 118498273 4548590 1836693..1837148 1 NC_008601.1 hypothetical protein 1837148 4548590 FTN_1712 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899323.1 1836693 D 401614 CDS YP_899324.1 118498274 4548591 complement(1837161..1837808) 1 NC_008601.1 hypothetical protein 1837808 4548591 FTN_1713 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899324.1 1837161 R 401614 CDS YP_899325.1 118498275 4548592 complement(1837873..1838559) 1 NC_008601.1 two-component response regulator 1838559 kdpE 4548592 kdpE Francisella tularensis subsp. novicida U112 two-component response regulator YP_899325.1 1837873 R 401614 CDS YP_899326.1 118498276 4548593 complement(1838601..1841282) 1 NC_008601.1 two component regulator, sensor histidine kinase kdpD 1841282 kdpD 4548593 kdpD Francisella tularensis subsp. novicida U112 two component regulator, sensor histidine kinase kdpD YP_899326.1 1838601 R 401614 CDS YP_899327.1 118498277 4548594 complement(1841386..1841940) 1 NC_008601.1 potassium-transporting ATPase C chain 1841940 kdpC 4548594 kdpC Francisella tularensis subsp. novicida U112 potassium-transporting ATPase C chain YP_899327.1 1841386 R 401614 CDS YP_899328.1 118498278 4548595 complement(1841957..1843996) 1 NC_008601.1 potassium-transporting ATPase B chain 1843996 kdpB 4548595 kdpB Francisella tularensis subsp. novicida U112 potassium-transporting ATPase B chain YP_899328.1 1841957 R 401614 CDS YP_899329.1 118498279 4548596 complement(1844006..1845727) 1 NC_008601.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A 1845727 kdpA 4548596 kdpA Francisella tularensis subsp. novicida U112 potassium-transporting ATPase subunit A YP_899329.1 1844006 R 401614 CDS YP_899330.1 118498280 4548597 complement(1846030..1847178) 1 NC_008601.1 Catalyzes the reversible two-electron oxidation of formate to carbon dioxide. It allows the assimilation of carbon dioxide and provides energy for growth through oxidative phosphorylation coupled to the reduction of oxygen, nitrate, sulphate or fumarate; formate dehydrogenase 1847178 4548597 FTN_1719 Francisella tularensis subsp. novicida U112 formate dehydrogenase YP_899330.1 1846030 R 401614 CDS YP_899331.1 118498281 4548603 complement(1852727..1853917) 1 NC_008601.1 aspartate aminotransferase 1853917 aspC 4548603 aspC Francisella tularensis subsp. novicida U112 aspartate aminotransferase YP_899331.1 1852727 R 401614 CDS YP_899332.1 118498282 4548604 complement(1853935..1855098) 1 NC_008601.1 pyridoxal-dependent decarboxylase 1855098 4548604 FTN_1726 Francisella tularensis subsp. novicida U112 pyridoxal-dependent decarboxylase YP_899332.1 1853935 R 401614 CDS YP_899333.1 118498283 4548605 complement(1855152..1855901) 1 NC_008601.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 1855901 dapD 4548605 dapD Francisella tularensis subsp. novicida U112 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_899333.1 1855152 R 401614 CDS YP_899334.1 118498284 4548606 complement(1855925..1856812) 1 NC_008601.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 1856812 dapA 4548606 dapA Francisella tularensis subsp. novicida U112 dihydrodipicolinate synthase YP_899334.1 1855925 R 401614 CDS YP_899335.1 118498285 4548607 complement(1856803..1857474) 1 NC_008601.1 dihydrodipicolinate reductase 1857474 dapB 4548607 dapB Francisella tularensis subsp. novicida U112 dihydrodipicolinate reductase YP_899335.1 1856803 R 401614 CDS YP_899336.1 118498286 4548608 complement(1857486..1858841) 1 NC_008601.1 aspartate kinase III 1858841 lysC 4548608 lysC Francisella tularensis subsp. novicida U112 aspartate kinase III YP_899336.1 1857486 R 401614 CDS YP_899337.1 118498287 4548668 complement(1859253..1860191) 1 NC_008601.1 proline iminopeptidase 1860191 pip 4548668 pip Francisella tularensis subsp. novicida U112 proline iminopeptidase YP_899337.1 1859253 R 401614 CDS YP_899338.1 118498288 4548669 complement(1860267..1861013) 1 NC_008601.1 Mg-dependent DNase 1861013 4548669 FTN_1732 Francisella tularensis subsp. novicida U112 Mg-dependent DNase YP_899338.1 1860267 R 401614 CDS YP_899339.1 118498289 4548670 complement(1861014..1861637) 1 NC_008601.1 nicotinamide ribonucleoside (NR) uptake permease (PnuC) family protein 1861637 4548670 FTN_1733 Francisella tularensis subsp. novicida U112 nicotinamide ribonucleoside (NR) uptake permease (PnuC) family protein YP_899339.1 1861014 R 401614 CDS YP_899340.1 118498290 4548671 1861861..1862253 1 NC_008601.1 hypothetical protein 1862253 4548671 FTN_1734 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899340.1 1861861 D 401614 CDS YP_899341.1 118498291 4548672 1862274..1862684 1 NC_008601.1 hypothetical protein 1862684 4548672 FTN_1735 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899341.1 1862274 D 401614 CDS YP_899342.1 118498292 4548673 1862687..1863085 1 NC_008601.1 hypothetical protein 1863085 4548673 FTN_1736 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899342.1 1862687 D 401614 CDS YP_899343.1 118498293 4548674 1863156..1864574 1 NC_008601.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein 1864574 eriC 4548674 eriC Francisella tularensis subsp. novicida U112 chloride channel protein YP_899343.1 1863156 D 401614 CDS YP_899344.1 118498294 4548675 1864510..1866015 1 NC_008601.1 metallocarboxypeptidase 1866015 4548675 FTN_1738 Francisella tularensis subsp. novicida U112 metallocarboxypeptidase YP_899344.1 1864510 D 401614 CDS YP_899345.1 118498295 4548676 1866821..1868011 1 NC_008601.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1868011 trpB 4548676 trpB Francisella tularensis subsp. novicida U112 tryptophan synthase subunit beta YP_899345.1 1866821 D 401614 CDS YP_899346.1 118498296 4548677 1868014..1868820 1 NC_008601.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1868820 trpA 4548677 trpA Francisella tularensis subsp. novicida U112 tryptophan synthase subunit alpha YP_899346.1 1868014 D 401614 CDS YP_899347.1 118498297 4548678 complement(1868875..1869228) 1 NC_008601.1 hypothetical protein 1869228 4548678 FTN_1741 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899347.1 1868875 R 401614 CDS YP_899348.1 118498298 4548679 complement(1869318..1870028) 1 NC_008601.1 nicotinamide mononucleotide transporter 1870028 pnuC 4548679 pnuC Francisella tularensis subsp. novicida U112 nicotinamide mononucleotide transporter YP_899348.1 1869318 R 401614 CDS YP_899349.1 118498299 4548680 1870244..1872823 1 NC_008601.1 chaperone clpB 1872823 clpB 4548680 clpB Francisella tularensis subsp. novicida U112 chaperone clpB YP_899349.1 1870244 D 401614 CDS YP_899350.1 118498300 4548681 1873074..1875266 1 NC_008601.1 chitinase 1875266 chiB 4548681 chiB Francisella tularensis subsp. novicida U112 chitinase YP_899350.1 1873074 D 401614 CDS YP_899351.1 118498301 4548682 1875320..1876480 1 NC_008601.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 1876480 purT 4548682 purT Francisella tularensis subsp. novicida U112 phosphoribosylglycinamide formyltransferase 2 YP_899351.1 1875320 D 401614 CDS YP_899352.1 118498302 4548684 complement(1877218..1877859) 1 NC_008601.1 hypothetical protein 1877859 4548684 FTN_1747 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899352.1 1877218 R 401614 CDS YP_899353.1 118498303 4548685 1878089..1878412 1 NC_008601.1 4Fe-4S ferredoxin 1878412 4548685 FTN_1748 Francisella tularensis subsp. novicida U112 4Fe-4S ferredoxin YP_899353.1 1878089 D 401614 CDS YP_899354.1 118498304 4548686 1878575..1879327 1 NC_008601.1 acyltransferase 1879327 4548686 FTN_1749 Francisella tularensis subsp. novicida U112 acyltransferase YP_899354.1 1878575 D 401614 CDS YP_899355.1 118498305 4548687 1879341..1880081 1 NC_008601.1 acyltransferase 1880081 4548687 FTN_1750 Francisella tularensis subsp. novicida U112 acyltransferase YP_899355.1 1879341 D 401614 CDS YP_899356.1 118498306 4548688 complement(1880087..1880806) 1 NC_008601.1 hypothetical protein 1880806 4548688 FTN_1751 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899356.1 1880087 R 401614 CDS YP_899357.1 118498307 4548689 complement(1880871..1882022) 1 NC_008601.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 1882022 nhaA 4548689 nhaA Francisella tularensis subsp. novicida U112 pH-dependent sodium/proton antiporter YP_899357.1 1880871 R 401614 CDS YP_899358.1 118498308 4548690 1882116..1883012 1 NC_008601.1 Rieske (2Fe-2S) domain-containing protein 1883012 4548690 FTN_1753 Francisella tularensis subsp. novicida U112 Rieske (2Fe-2S) domain-containing protein YP_899358.1 1882116 D 401614 CDS YP_899359.1 118498309 4548691 1883079..1883588 1 NC_008601.1 cytochrome b561 family protein 1883588 4548691 FTN_1754 Francisella tularensis subsp. novicida U112 cytochrome b561 family protein YP_899359.1 1883079 D 401614 CDS YP_899360.1 118498310 4548692 1883615..1884874 1 NC_008601.1 metabolite:H+ symporter (MHS) family protein 1884874 4548692 FTN_1755 Francisella tularensis subsp. novicida U112 metabolite:H+ symporter (MHS) family protein YP_899360.1 1883615 D 401614 CDS YP_899361.1 118498311 4548693 1885175..1885654 1 NC_008601.1 bacterioferritin comigratory protein 1885654 bcp 4548693 bcp Francisella tularensis subsp. novicida U112 bacterioferritin comigratory protein YP_899361.1 1885175 D 401614 CDS YP_899362.1 118498312 4548694 complement(1885732..1886715) 1 NC_008601.1 D-isomer specific 2-hydroxyacid dehydrogenase 1886715 4548694 FTN_1757 Francisella tularensis subsp. novicida U112 D-isomer specific 2-hydroxyacid dehydrogenase YP_899362.1 1885732 R 401614 CDS YP_899363.1 118498313 4548695 1887821..1888441 1 NC_008601.1 hypothetical protein 1888441 4548695 FTN_1758 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899363.1 1887821 D 401614 CDS YP_899364.1 118498314 4548696 complement(1888509..1888901) 1 NC_008601.1 hypothetical protein 1888901 4548696 FTN_1759 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899364.1 1888509 R 401614 CDS YP_899365.1 118498315 4548697 1889010..1889999 1 NC_008601.1 zinc-binding alcohol dehydrogenase 1889999 4548697 FTN_1760 Francisella tularensis subsp. novicida U112 zinc-binding alcohol dehydrogenase YP_899365.1 1889010 D 401614 CDS YP_899366.1 118498316 4548699 complement(1890744..1892423) 1 NC_008601.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein 1892423 4548699 FTN_1762 Francisella tularensis subsp. novicida U112 putative ABC transporter ATP-binding protein YP_899366.1 1890744 R 401614 CDS YP_899367.1 118498317 4548700 1892635..1893855 1 NC_008601.1 metabolite:H+ symporter (MHS) family protein 1893855 4548700 FTN_1763 Francisella tularensis subsp. novicida U112 metabolite:H+ symporter (MHS) family protein YP_899367.1 1892635 D 401614 CDS YP_899368.1 118498318 4548701 complement(1893872..1894084) 1 NC_008601.1 hypothetical protein 1894084 4548701 FTN_1764 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899368.1 1893872 R 401614 CDS YP_899369.1 118498319 4548702 1894130..1895101 1 NC_008601.1 hypothetical protein 1895101 4548702 FTN_1765 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899369.1 1894130 D 401614 CDS YP_899370.1 118498320 4548703 complement(1895111..1896115) 1 NC_008601.1 drug/metabolite transporter (DMT) superfamily protein 1896115 4548703 FTN_1766 Francisella tularensis subsp. novicida U112 drug/metabolite transporter (DMT) superfamily protein YP_899370.1 1895111 R 401614 CDS YP_899371.1 118498321 4548704 complement(1896132..1897052) 1 NC_008601.1 ribokinase 1897052 rbsK 4548704 rbsK Francisella tularensis subsp. novicida U112 ribokinase YP_899371.1 1896132 R 401614 CDS YP_899372.1 118498322 4548745 complement(1897170..1899746) 1 NC_008601.1 aminopeptidase N 1899746 pepN 4548745 pepN Francisella tularensis subsp. novicida U112 aminopeptidase N YP_899372.1 1897170 R 401614 CDS YP_899373.1 118498323 4548746 1899948..1900376 1 NC_008601.1 HSP20 family protein 1900376 4548746 FTN_1769 Francisella tularensis subsp. novicida U112 HSP20 family protein YP_899373.1 1899948 D 401614 CDS YP_899374.1 118498324 4548747 complement(1900373..1901734) 1 NC_008601.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 1901734 4548747 FTN_1770 Francisella tularensis subsp. novicida U112 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase YP_899374.1 1900373 R 401614 CDS YP_899375.1 118498325 4548748 complement(1901826..1902239) 1 NC_008601.1 hypothetical protein 1902239 4548748 FTN_1771 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899375.1 1901826 R 401614 CDS YP_899376.1 118498326 4548749 complement(1902244..1902933) 1 NC_008601.1 peptide methionine sulfoxide reductase 1902933 4548749 FTN_1772 Francisella tularensis subsp. novicida U112 peptide methionine sulfoxide reductase YP_899376.1 1902244 R 401614 CDS YP_899377.1 118498327 4548750 complement(1903017..1903385) 1 NC_008601.1 hypothetical protein 1903385 4548750 FTN_1773 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899377.1 1903017 R 401614 CDS YP_899378.1 118498328 4548751 complement(1903378..1903719) 1 NC_008601.1 hypothetical protein 1903719 4548751 FTN_1774 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899378.1 1903378 R 401614 CDS YP_899379.1 118498329 4548752 complement(1903788..1904228) 1 NC_008601.1 hypothetical protein 1904228 4548752 FTN_1775 Francisella tularensis subsp. novicida U112 hypothetical protein YP_899379.1 1903788 R 401614 CDS YP_899380.1 118498330 4548753 complement(1904290..1905303) 1 NC_008601.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 1905303 trpD 4548753 trpD Francisella tularensis subsp. novicida U112 anthranilate phosphoribosyltransferase YP_899380.1 1904290 R 401614 CDS YP_899381.1 118498331 4548754 complement(1905300..1905878) 1 NC_008601.1 anthranilate synthase component II 1905878 trpG 4548754 trpG Francisella tularensis subsp. novicida U112 anthranilate synthase component II YP_899381.1 1905300 R 401614 CDS YP_899382.1 118498332 4548755 complement(1905882..1907426) 1 NC_008601.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1907426 trpE 4548755 trpE Francisella tularensis subsp. novicida U112 anthranilate synthase component I YP_899382.1 1905882 R 401614 CDS YP_899383.1 118498333 4548756 complement(1907435..1907722) 1 NC_008601.1 trp operon repressor 1907722 trpR 4548756 trpR Francisella tularensis subsp. novicida U112 trp operon repressor YP_899383.1 1907435 R 401614 CDS YP_899384.1 118498334 4548759 complement(1908197..1909693) 1 NC_008601.1 ribonuclease G 1909693 rng 4548759 rng Francisella tularensis subsp. novicida U112 ribonuclease G YP_899384.1 1908197 R 401614 CDS