-- dump date 20140619_095004 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 401614000001 SEQ_END SEQ_END NC_008601.1 1910031 1910031 DR NC_008601.1; contig end 1910031..1910031 Francisella tularensis subsp. novicida U112 YP_897666.1 CDS dnaA NC_008601.1 145 1620 D binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 145..1620 Francisella tularensis subsp. novicida U112 4547377 YP_897667.1 CDS dnaN NC_008601.1 1657 2760 D DNA polymerase III subunit beta 1657..2760 Francisella tularensis subsp. novicida U112 4547378 YP_897668.1 CDS FTN_0003 NC_008601.1 2791 4044 R metabolite:H+ symporter (MHS) family protein complement(2791..4044) Francisella tularensis subsp. novicida U112 4547379 YP_897669.1 CDS FTN_0004 NC_008601.1 4244 5767 D aspartate/glutamate transporter 4244..5767 Francisella tularensis subsp. novicida U112 4547380 YP_897670.1 CDS corA NC_008601.1 5832 6803 D divalent inorganic cation transporter 5832..6803 Francisella tularensis subsp. novicida U112 4547381 YP_897671.1 CDS FTN_0006 NC_008601.1 6816 7283 R hypothetical protein complement(6816..7283) Francisella tularensis subsp. novicida U112 4548498 YP_897672.1 CDS FTN_0007 NC_008601.1 7361 7678 R hypothetical protein complement(7361..7678) Francisella tularensis subsp. novicida U112 4548499 YP_897673.1 CDS FTN_0008 NC_008601.1 7768 8640 R drug/metabolite exporter protein complement(7768..8640) Francisella tularensis subsp. novicida U112 4548500 YP_897674.1 CDS FTN_0009 NC_008601.1 8784 8966 D hypothetical protein 8784..8966 Francisella tularensis subsp. novicida U112 4548501 YP_897675.1 CDS FTN_0010 NC_008601.1 9372 9806 R phage terminase small subunit complement(9372..9806) Francisella tularensis subsp. novicida U112 4548502 YP_897676.1 CDS FTN_0011 NC_008601.1 10041 10220 R hypothetical protein complement(10041..10220) Francisella tularensis subsp. novicida U112 4548503 YP_897677.1 CDS FTN_0012 NC_008601.1 10217 10438 R hypothetical protein complement(10217..10438) Francisella tularensis subsp. novicida U112 4548504 YP_897678.1 CDS FTN_0013 NC_008601.1 10936 11835 R hypothetical protein complement(10936..11835) Francisella tularensis subsp. novicida U112 4548505 YP_897679.1 CDS FTN_0014 NC_008601.1 11832 12728 R hypothetical protein complement(11832..12728) Francisella tularensis subsp. novicida U112 4548506 YP_897680.1 CDS FTN_0015 NC_008601.1 12732 12911 R AlpA family regulatory protein complement(12732..12911) Francisella tularensis subsp. novicida U112 4548507 YP_897681.1 CDS FTN_0016 NC_008601.1 13107 13781 R hypothetical protein complement(13107..13781) Francisella tularensis subsp. novicida U112 4548508 YP_897682.1 CDS FTN_0017 NC_008601.1 13786 15027 R phage integrase complement(13786..15027) Francisella tularensis subsp. novicida U112 4548509 YP_897683.1 CDS sdaC NC_008601.1 15685 16908 R serine permease complement(15685..16908) Francisella tularensis subsp. novicida U112 4548510 YP_897684.1 CDS pyrB NC_008601.1 17049 17975 R aspartate carbamoyltransferase complement(17049..17975) Francisella tularensis subsp. novicida U112 4548511 YP_897685.1 CDS carB NC_008601.1 18117 21401 R four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit complement(18117..21401) Francisella tularensis subsp. novicida U112 4548512 YP_897686.1 CDS carA NC_008601.1 21406 22572 R catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit complement(21406..22572) Francisella tularensis subsp. novicida U112 4548513 YP_897687.1 CDS FTN_0022 NC_008601.1 22992 24047 D histidine acid phosphatase 22992..24047 Francisella tularensis subsp. novicida U112 4548514 YP_897688.1 CDS tmpT NC_008601.1 24068 24748 R catalyzes the S-adenosylmethionine-dependent transmethylation of thiopurine compounds; may be involved in selenium cycling by forming dimethylselenide and/or dimethyldiselenide; thiopurine S-methyltransferase complement(24068..24748) Francisella tularensis subsp. novicida U112 4548515 YP_897689.1 CDS pyrC NC_008601.1 24880 26226 D Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; dihydroorotase 24880..26226 Francisella tularensis subsp. novicida U112 4548516 YP_897690.1 CDS FTN_0025 NC_008601.1 26210 26797 R hypothetical protein complement(26210..26797) Francisella tularensis subsp. novicida U112 4548517 YP_897691.1 CDS FTN_0026 NC_008601.1 27076 27330 D hypothetical protein 27076..27330 Francisella tularensis subsp. novicida U112 4547493 YP_897692.1 CDS FTN_0027 NC_008601.1 28044 28595 D hypothetical protein 28044..28595 Francisella tularensis subsp. novicida U112 4547494 YP_897693.1 CDS FTN_0028 NC_008601.1 28711 29763 R hypothetical protein complement(28711..29763) Francisella tularensis subsp. novicida U112 4547495 YP_897694.1 CDS FTN_0029 NC_008601.1 29750 30715 R HlyD family membrane fusion protein complement(29750..30715) Francisella tularensis subsp. novicida U112 4547496 YP_897695.1 CDS FTN_0030 NC_008601.1 30802 31209 R hypothetical protein complement(30802..31209) Francisella tularensis subsp. novicida U112 4547497 YP_897696.1 CDS FTN_0031 NC_008601.1 31335 32204 D LysR family transcriptional regulator 31335..32204 Francisella tularensis subsp. novicida U112 4547498 YP_897697.1 CDS FTN_0032 NC_008601.1 32205 32831 R hypothetical protein complement(32205..32831) Francisella tularensis subsp. novicida U112 4547499 YP_897698.1 CDS FTN_0033 NC_008601.1 32974 33522 D chorismate mutase 32974..33522 Francisella tularensis subsp. novicida U112 4547500 YP_897699.1 CDS FTN_0034 NC_008601.1 33577 36951 R hypothetical protein complement(33577..36951) Francisella tularensis subsp. novicida U112 4547501 YP_897700.1 CDS pyrF NC_008601.1 37218 37862 D orotidine-5'-phosphate decarboxylase 37218..37862 Francisella tularensis subsp. novicida U112 4547502 YP_897701.1 CDS pyrD NC_008601.1 37864 38604 D dihydroorotate oxidase 37864..38604 Francisella tularensis subsp. novicida U112 4547503 YP_897702.1 CDS FTN_0037 NC_008601.1 40003 40347 R hypothetical protein complement(40003..40347) Francisella tularensis subsp. novicida U112 4547504 YP_897703.1 CDS FTN_0038 NC_008601.1 40366 40650 R hypothetical protein complement(40366..40650) Francisella tularensis subsp. novicida U112 4547505 YP_897704.1 CDS FTN_0039 NC_008601.1 40653 41078 R hypothetical protein complement(40653..41078) Francisella tularensis subsp. novicida U112 4547506 YP_897705.1 CDS FTN_0040 NC_008601.1 41093 44347 R hypothetical protein complement(41093..44347) Francisella tularensis subsp. novicida U112 4547507 YP_897706.1 CDS FTN_0041 NC_008601.1 44366 46582 R hypothetical protein complement(44366..46582) Francisella tularensis subsp. novicida U112 4547508 YP_897707.1 CDS FTN_0042 NC_008601.1 46882 47439 D hypothetical protein 46882..47439 Francisella tularensis subsp. novicida U112 4547509 YP_897708.1 CDS FTN_0043 NC_008601.1 47436 48968 D hypothetical protein 47436..48968 Francisella tularensis subsp. novicida U112 4547510 YP_897709.1 CDS FTN_0044 NC_008601.1 49002 49649 D hypothetical protein 49002..49649 Francisella tularensis subsp. novicida U112 4548536 YP_897710.1 CDS FTN_0045 NC_008601.1 49665 50744 D hypothetical protein 49665..50744 Francisella tularensis subsp. novicida U112 4548537 YP_897711.1 CDS FTN_0046 NC_008601.1 50758 53736 D hypothetical protein 50758..53736 Francisella tularensis subsp. novicida U112 4548538 YP_897712.1 CDS FTN_0047 NC_008601.1 53754 57530 D hypothetical protein 53754..57530 Francisella tularensis subsp. novicida U112 4548539 YP_897713.1 CDS FTN_0048 NC_008601.1 57540 58760 D hypothetical protein 57540..58760 Francisella tularensis subsp. novicida U112 4548540 YP_897714.1 CDS FTN_0049 NC_008601.1 58770 59594 D hypothetical protein 58770..59594 Francisella tularensis subsp. novicida U112 4548541 YP_897715.1 CDS FTN_0050 NC_008601.1 59569 61092 D hypothetical protein 59569..61092 Francisella tularensis subsp. novicida U112 4548542 YP_897716.1 CDS FTN_0051 NC_008601.1 61102 61710 D hypothetical protein 61102..61710 Francisella tularensis subsp. novicida U112 4548543 YP_897717.1 CDS FTN_0052 NC_008601.1 61717 63780 D hypothetical protein 61717..63780 Francisella tularensis subsp. novicida U112 4548544 YP_897718.1 CDS FTN_0053 NC_008601.1 63789 64394 D hypothetical protein 63789..64394 Francisella tularensis subsp. novicida U112 4548545 YP_897719.1 CDS FTN_0054 NC_008601.1 64387 64767 D hypothetical protein 64387..64767 Francisella tularensis subsp. novicida U112 4548546 YP_897720.1 CDS tyrA NC_008601.1 64847 65683 R prephenate dehydrogenase complement(64847..65683) Francisella tularensis subsp. novicida U112 4548547 YP_897721.1 CDS dtd NC_008601.1 65951 66388 R hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase complement(65951..66388) Francisella tularensis subsp. novicida U112 4548548 YP_897722.1 CDS FTN_0057 NC_008601.1 66662 67894 R major facilitator transporter complement(66662..67894) Francisella tularensis subsp. novicida U112 4548549 YP_897723.1 CDS FTN_0058 NC_008601.1 67913 69628 R beta-fructofuranosidase complement(67913..69628) Francisella tularensis subsp. novicida U112 4548550 YP_897724.1 CDS leuB NC_008601.1 69704 70783 R 3-isopropylmalate dehydrogenase complement(69704..70783) Francisella tularensis subsp. novicida U112 4548551 YP_897725.1 CDS leuD NC_008601.1 70785 71354 R catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit complement(70785..71354) Francisella tularensis subsp. novicida U112 4548552 YP_897726.1 CDS leuC NC_008601.1 71357 72766 R dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit complement(71357..72766) Francisella tularensis subsp. novicida U112 4548553 YP_897727.1 CDS leuA NC_008601.1 72768 74348 R 2-isopropylmalate synthase complement(72768..74348) Francisella tularensis subsp. novicida U112 4548554 YP_897728.1 CDS ilvE NC_008601.1 74359 75246 R branched-chain amino acid aminotransferase complement(74359..75246) Francisella tularensis subsp. novicida U112 4548555 YP_897729.1 CDS ppdK NC_008601.1 75645 78278 R catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase complement(75645..78278) Francisella tularensis subsp. novicida U112 4547644 YP_897730.1 CDS FTN_0065 NC_008601.1 78555 78869 R hypothetical protein complement(78555..78869) Francisella tularensis subsp. novicida U112 4547645 YP_897731.1 CDS feoB NC_008601.1 79068 81317 R ferrous iron transport protein B complement(79068..81317) Francisella tularensis subsp. novicida U112 4547646 YP_897732.1 CDS FTN_0067 NC_008601.1 81418 82032 R hypothetical protein complement(81418..82032) Francisella tularensis subsp. novicida U112 4547647 YP_897733.1 CDS orn NC_008601.1 82047 82583 R 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease complement(82047..82583) Francisella tularensis subsp. novicida U112 4547648 YP_897734.1 CDS efp NC_008601.1 82586 83155 R Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P complement(82586..83155) Francisella tularensis subsp. novicida U112 4547649 YP_897735.1 CDS pilE NC_008601.1 83196 83603 R Type IV pili, pilus assembly protein complement(83196..83603) Francisella tularensis subsp. novicida U112 4547650 YP_897736.1 CDS FTN_0071 NC_008601.1 83616 84539 R LPS fatty acid acyltransferase complement(83616..84539) Francisella tularensis subsp. novicida U112 4547651 YP_897737.1 CDS FTN_0072 NC_008601.1 84600 85499 R LPS fatty acid acyltransferase complement(84600..85499) Francisella tularensis subsp. novicida U112 4547652 YP_897738.1 CDS FTN_0073 NC_008601.1 85506 87161 R membrane protein complement(85506..87161) Francisella tularensis subsp. novicida U112 4547653 YP_897739.1 CDS FTN_0074 NC_008601.1 87170 87418 R hypothetical protein complement(87170..87418) Francisella tularensis subsp. novicida U112 4547654 YP_897740.1 CDS rnpA NC_008601.1 87394 87747 R ribonuclease P protein component complement(87394..87747) Francisella tularensis subsp. novicida U112 4547655 YP_897741.1 CDS rpmH NC_008601.1 87737 87871 R in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 complement(87737..87871) Francisella tularensis subsp. novicida U112 4547656 YP_897742.1 CDS FTN_0077 NC_008601.1 87963 88421 R hypothetical protein complement(87963..88421) Francisella tularensis subsp. novicida U112 4547657 YP_897743.1 CDS aroE NC_008601.1 88548 89321 D shikimate 5-dehydrogenase 88548..89321 Francisella tularensis subsp. novicida U112 4547658 YP_897744.1 CDS murC NC_008601.1 89393 90748 D UDP-N-acetylmuramate-alanine ligase 89393..90748 Francisella tularensis subsp. novicida U112 4547659 YP_897745.1 CDS FTN_0080 NC_008601.1 90741 91613 D SAM-dependent methyltransferase 90741..91613 Francisella tularensis subsp. novicida U112 4547660 YP_897746.1 CDS FTN_0081 NC_008601.1 91624 92358 R hypothetical protein complement(91624..92358) Francisella tularensis subsp. novicida U112 4547661 YP_897747.1 CDS FTN_0082 NC_008601.1 92435 92998 D HAD superfamily hydrolase 92435..92998 Francisella tularensis subsp. novicida U112 4547662 YP_897748.1 CDS FTN_0083 NC_008601.1 93070 93828 D hypothetical protein 93070..93828 Francisella tularensis subsp. novicida U112 4548930 YP_897749.1 CDS FTN_0084 NC_008601.1 93832 96573 D DNA/RNA helicase 93832..96573 Francisella tularensis subsp. novicida U112 4548931 YP_897750.1 CDS uspA NC_008601.1 96649 97485 D universal stress protein 96649..97485 Francisella tularensis subsp. novicida U112 4548932 YP_897751.1 CDS FTN_0086 NC_008601.1 97601 98830 D metabolite:H+ symporter (MHS) family protein 97601..98830 Francisella tularensis subsp. novicida U112 4548933 YP_897752.1 CDS FTN_0087 NC_008601.1 98862 99479 D allophanate hydrolase subunit 1 98862..99479 Francisella tularensis subsp. novicida U112 4548934 YP_897753.1 CDS FTN_0088 NC_008601.1 99479 100177 D LamB/YcsF family protein 99479..100177 Francisella tularensis subsp. novicida U112 4548935 YP_897754.1 CDS FTN_0089 NC_008601.1 100182 100994 D hydrolase subunit 100182..100994 Francisella tularensis subsp. novicida U112 4548936 YP_897755.1 CDS FTN_0090 NC_008601.1 101001 102545 R acid phosphatase complement(101001..102545) Francisella tularensis subsp. novicida U112 4548937 YP_897756.1 CDS FTN_0091 NC_008601.1 102854 103510 D hypothetical protein 102854..103510 Francisella tularensis subsp. novicida U112 4548938 YP_897757.1 CDS FTN_0092 NC_008601.1 103528 104523 D inorganic phosphate transporter (PiT) family protein 103528..104523 Francisella tularensis subsp. novicida U112 4548939 YP_897758.1 CDS FTN_0093 NC_008601.1 104604 105119 D cytochrome b561 family protein 104604..105119 Francisella tularensis subsp. novicida U112 4548940 YP_897759.1 CDS FTN_0094 NC_008601.1 105126 106073 R LysR family transcriptional regulator complement(105126..106073) Francisella tularensis subsp. novicida U112 4548941 YP_897760.1 CDS FTN_0095 NC_008601.1 106142 106807 R nitroreductase complement(106142..106807) Francisella tularensis subsp. novicida U112 4548942 YP_897761.1 CDS FTN_0096 NC_008601.1 107210 107902 D hypothetical protein 107210..107902 Francisella tularensis subsp. novicida U112 4548943 YP_897762.1 CDS FTN_0097 NC_008601.1 107899 109104 R hydroxy/aromatic amino acid permease (HAAAP) family protein complement(107899..109104) Francisella tularensis subsp. novicida U112 4548944 YP_897763.1 CDS gidB NC_008601.1 109204 109821 D glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 109204..109821 Francisella tularensis subsp. novicida U112 4548945 YP_897764.1 CDS FTN_0099 NC_008601.1 109818 110486 D hypothetical protein 109818..110486 Francisella tularensis subsp. novicida U112 4548946 YP_897765.1 CDS FTN_0100 NC_008601.1 110479 111495 R hypothetical protein complement(110479..111495) Francisella tularensis subsp. novicida U112 4548947 YP_897766.1 CDS FTN_0101 NC_008601.1 111566 112462 R LysR family transcriptional regulator complement(111566..112462) Francisella tularensis subsp. novicida U112 4548948 YP_897767.1 CDS FTN_0102 NC_008601.1 112565 113719 D major facilitator transporter 112565..113719 Francisella tularensis subsp. novicida U112 4548949 YP_897768.1 CDS FTN_0103 NC_008601.1 113785 116088 R hypothetical protein complement(113785..116088) Francisella tularensis subsp. novicida U112 4547761 YP_897769.1 CDS FTN_0104 NC_008601.1 116266 116862 D phosphoheptose isomerase 116266..116862 Francisella tularensis subsp. novicida U112 4547762 YP_897770.1 CDS FTN_0105 NC_008601.1 116870 117226 D outer membrane lipoprotein 116870..117226 Francisella tularensis subsp. novicida U112 4547763 YP_897771.1 CDS rpsT NC_008601.1 117300 117572 R binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 complement(117300..117572) Francisella tularensis subsp. novicida U112 4547764 YP_897772.1 CDS lepA NC_008601.1 117842 119626 D binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 117842..119626 Francisella tularensis subsp. novicida U112 4547765 YP_897773.1 CDS mnmA NC_008601.1 119640 120719 D catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 119640..120719 Francisella tularensis subsp. novicida U112 4547766 YP_897774.1 CDS FTN_0109 NC_008601.1 120737 121717 R hypothetical protein complement(120737..121717) Francisella tularensis subsp. novicida U112 4547767 YP_897775.1 CDS FTN_0110 NC_008601.1 121812 122336 R peptide deformylase complement(121812..122336) Francisella tularensis subsp. novicida U112 4547768 YP_897776.1 CDS ribH NC_008601.1 122333 122776 R riboflavin synthase beta-chain complement(122333..122776) Francisella tularensis subsp. novicida U112 4547769 YP_897777.1 CDS ribAB NC_008601.1 122786 123997 R 3,4-dihydroxy-2-butanone 4-phosphate synthase complement(122786..123997) Francisella tularensis subsp. novicida U112 4547770 YP_897778.1 CDS ribC NC_008601.1 123990 124595 R catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha complement(123990..124595) Francisella tularensis subsp. novicida U112 4547771 YP_897779.1 CDS ribD NC_008601.1 124588 125655 R pyrimidine reductase/pyrimidine deaminase complement(124588..125655) Francisella tularensis subsp. novicida U112 4547772 YP_897780.1 CDS FTN_0115 NC_008601.1 126046 127296 D Na+/H+ antiporter 126046..127296 Francisella tularensis subsp. novicida U112 4547773 YP_897781.1 CDS ipdC NC_008601.1 127306 129003 R indolepyruvate decarboxylase complement(127306..129003) Francisella tularensis subsp. novicida U112 4547774 YP_897782.1 CDS FTN_0117 NC_008601.1 129104 129457 R ferredoxin complement(129104..129457) Francisella tularensis subsp. novicida U112 4547775 YP_897783.1 CDS FTN_0118 NC_008601.1 129531 130454 D S49 family serine peptidase 129531..130454 Francisella tularensis subsp. novicida U112 4547776 YP_897784.1 CDS FTN_0119 NC_008601.1 130544 131083 D hypothetical protein 130544..131083 Francisella tularensis subsp. novicida U112 4547777 YP_897785.1 CDS FTN_0120 NC_008601.1 131219 131641 D rhodanese-related sulfurtransferase 131219..131641 Francisella tularensis subsp. novicida U112 4547778 YP_897786.1 CDS secB1 NC_008601.1 131668 132117 D molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 131668..132117 Francisella tularensis subsp. novicida U112 4547779 YP_897787.1 CDS recA NC_008601.1 132141 133220 D catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 132141..133220 Francisella tularensis subsp. novicida U112 4548478 YP_897788.1 CDS recX NC_008601.1 133207 133659 D inhibitor of RecA 133207..133659 Francisella tularensis subsp. novicida U112 4548479 YP_897789.1 CDS ssb NC_008601.1 133833 134312 D single-strand DNA binding protein 133833..134312 Francisella tularensis subsp. novicida U112 4548480 YP_897790.1 CDS ackA NC_008601.1 134418 135572 D propionate kinase 2 / acetate kinase A 134418..135572 Francisella tularensis subsp. novicida U112 4548481 YP_897791.1 CDS pta NC_008601.1 135582 137678 D catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; phosphate acetyltransferase 135582..137678 Francisella tularensis subsp. novicida U112 4548482 YP_897792.1 CDS gabD NC_008601.1 137693 139126 D succinate semialdehyde dehydrogenase 137693..139126 Francisella tularensis subsp. novicida U112 4548483 YP_897793.1 CDS FTN_0128 NC_008601.1 139163 140371 D metabolite:H+ symporter (MHS) family protein 139163..140371 Francisella tularensis subsp. novicida U112 4548484 YP_897794.1 CDS aspS NC_008601.1 140546 142324 D catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 140546..142324 Francisella tularensis subsp. novicida U112 4548485 YP_897795.1 CDS FTN_0130 NC_008601.1 142461 143405 D group 1 glycosyl transferase 142461..143405 Francisella tularensis subsp. novicida U112 4548486 YP_897796.1 CDS FTN_0131 NC_008601.1 143587 144894 R hypothetical protein complement(143587..144894) Francisella tularensis subsp. novicida U112 4548487 YP_897797.1 CDS FTN_0132 NC_008601.1 145232 146200 R hypothetical protein complement(145232..146200) Francisella tularensis subsp. novicida U112 4548488 YP_897798.1 CDS FTN_0133 NC_008601.1 146389 148245 D ribonuclease II family protein 146389..148245 Francisella tularensis subsp. novicida U112 4548489 YP_897799.1 CDS FTN_0134 NC_008601.1 148576 149244 D carboxylesterase/phospholipase family protein 148576..149244 Francisella tularensis subsp. novicida U112 4548490 YP_897800.1 CDS hemC NC_008601.1 149241 150143 D transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 149241..150143 Francisella tularensis subsp. novicida U112 4548491 YP_897801.1 CDS crcB NC_008601.1 150192 150536 D may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 150192..150536 Francisella tularensis subsp. novicida U112 4548492 YP_897802.1 CDS FTN_0137 NC_008601.1 150533 150940 D hypothetical protein 150533..150940 Francisella tularensis subsp. novicida U112 4548493 YP_897803.1 CDS FTN_0138 NC_008601.1 151080 151697 D hypothetical protein 151080..151697 Francisella tularensis subsp. novicida U112 4548494 YP_897804.1 CDS FTN_0139 NC_008601.1 151694 151867 R hypothetical protein complement(151694..151867) Francisella tularensis subsp. novicida U112 4548495 YP_897805.1 CDS FTN_0140 NC_008601.1 151997 153796 D anion ABC transporter permease 151997..153796 Francisella tularensis subsp. novicida U112 4548496 YP_897806.1 CDS FTN_0141 NC_008601.1 153815 155131 D ABC transporter ATP-binding protein 153815..155131 Francisella tularensis subsp. novicida U112 4548497 YP_897807.1 CDS FTN_0142 NC_008601.1 155218 156759 D hypothetical protein 155218..156759 Francisella tularensis subsp. novicida U112 4548152 YP_897808.1 CDS FTN_0143 NC_008601.1 156853 158739 D monovalent cation:proton antiporter 156853..158739 Francisella tularensis subsp. novicida U112 4548153 YP_897809.1 CDS paaY NC_008601.1 158724 159263 D carbonic anhydrase 158724..159263 Francisella tularensis subsp. novicida U112 4548154 YP_897810.1 CDS lolB NC_008601.1 159214 159858 D outer membrane lipoprotein LolB 159214..159858 Francisella tularensis subsp. novicida U112 4548155 YP_897811.1 CDS ipk NC_008601.1 159846 160673 D An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 159846..160673 Francisella tularensis subsp. novicida U112 4548156 YP_897812.1 CDS FTN_0148 NC_008601.1 160862 161491 D hypothetical protein 160862..161491 Francisella tularensis subsp. novicida U112 4548158 YP_897813.1 CDS FTN_0149 NC_008601.1 161561 162475 D hypothetical protein 161561..162475 Francisella tularensis subsp. novicida U112 4548159 YP_897814.1 CDS FTN_0150 NC_008601.1 162491 163060 D YggT family protein 162491..163060 Francisella tularensis subsp. novicida U112 4548160 YP_897815.1 CDS FTN_0151 NC_008601.1 163054 163836 R ABC transporter ATP-binding protein complement(163054..163836) Francisella tularensis subsp. novicida U112 4548161 YP_897816.1 CDS FTN_0152 NC_008601.1 163865 165589 R anion ABC transporter permease complement(163865..165589) Francisella tularensis subsp. novicida U112 4548162 YP_897817.1 CDS FTN_0153 NC_008601.1 166018 166443 R RimI-like acetyltransferase complement(166018..166443) Francisella tularensis subsp. novicida U112 4548163 YP_897818.1 CDS rimK NC_008601.1 166430 167899 R glutathione synthase/ribosomal protein S6 modification protein complement(166430..167899) Francisella tularensis subsp. novicida U112 4548164 YP_897819.1 CDS FTN_0155 NC_008601.1 168063 170078 D competence protein 168063..170078 Francisella tularensis subsp. novicida U112 4548165 YP_897820.1 CDS plsC NC_008601.1 170179 171066 D putative acyltransferase 170179..171066 Francisella tularensis subsp. novicida U112 4548166 YP_897821.1 CDS FTN_0157 NC_008601.1 171468 172004 R hypothetical protein complement(171468..172004) Francisella tularensis subsp. novicida U112 4548167 YP_897822.1 CDS FTN_0158 NC_008601.1 172102 172644 R Sua5/YciO/YrdC family protein complement(172102..172644) Francisella tularensis subsp. novicida U112 4548168 YP_897823.1 CDS rpsA NC_008601.1 172767 174437 R in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 complement(172767..174437) Francisella tularensis subsp. novicida U112 4548169 YP_897824.1 CDS FTN_0160 NC_008601.1 174585 175046 D zinc-binding protein 174585..175046 Francisella tularensis subsp. novicida U112 4548760 YP_897825.1 CDS ddlB NC_008601.1 175050 175940 D D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 175050..175940 Francisella tularensis subsp. novicida U112 4548761 YP_897826.1 CDS ftsQ NC_008601.1 175937 176620 D cell division protein FtsQ 175937..176620 Francisella tularensis subsp. novicida U112 4548762 YP_897827.1 CDS ftsA NC_008601.1 176722 177984 D cell division protein FtsA 176722..177984 Francisella tularensis subsp. novicida U112 4548763 YP_897828.1 CDS ftsZ NC_008601.1 178028 179173 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 178028..179173 Francisella tularensis subsp. novicida U112 4548764 YP_897829.1 CDS lpxC NC_008601.1 179199 180056 D zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 179199..180056 Francisella tularensis subsp. novicida U112 4548765 YP_897830.1 CDS dnaX NC_008601.1 180070 181710 R DNA polymerase III subunit gamma and tau complement(180070..181710) Francisella tularensis subsp. novicida U112 4548766 YP_897831.1 CDS prfB NC_008601.1 181982 182959 D peptide chain release factor 2 181982..182959 Francisella tularensis subsp. novicida U112 4548767 YP_897832.1 CDS lysU NC_008601.1 183091 184821 D lysyl-tRNA synthetase 183091..184821 Francisella tularensis subsp. novicida U112 4548768 YP_897833.1 CDS FTN_0169 NC_008601.1 185205 185747 R hypothetical protein complement(185205..185747) Francisella tularensis subsp. novicida U112 4548769 YP_897834.1 CDS FTN_0170 NC_008601.1 185846 186718 R hypothetical protein complement(185846..186718) Francisella tularensis subsp. novicida U112 4548770 YP_897835.1 CDS glsA NC_008601.1 186727 188268 R glutaminase complement(186727..188268) Francisella tularensis subsp. novicida U112 4548771 YP_897836.1 CDS glnA NC_008601.1 188350 189387 R glutamine synthetase complement(188350..189387) Francisella tularensis subsp. novicida U112 4548772 YP_897837.1 CDS holA NC_008601.1 189507 190484 R DNA polymerase III subunit delta complement(189507..190484) Francisella tularensis subsp. novicida U112 4548773 YP_897838.1 CDS blc NC_008601.1 190570 191088 D outer membrane lipoprotein 190570..191088 Francisella tularensis subsp. novicida U112 4548774 YP_897839.1 CDS FTN_0175 NC_008601.1 191251 192876 D hypothetical protein 191251..192876 Francisella tularensis subsp. novicida U112 4548775 YP_897840.1 CDS FTN_0176 NC_008601.1 193022 194290 D serine permease 193022..194290 Francisella tularensis subsp. novicida U112 4548776 YP_897841.1 CDS purH NC_008601.1 194356 195903 R involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase complement(194356..195903) Francisella tularensis subsp. novicida U112 4548777 YP_897842.1 CDS purA NC_008601.1 196080 197366 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 196080..197366 Francisella tularensis subsp. novicida U112 4548778 YP_897843.1 CDS hpt NC_008601.1 197370 197903 D hypoxanthine-guanine phosphoribosyltransferase 197370..197903 Francisella tularensis subsp. novicida U112 4548779 YP_897844.1 CDS FTN_0180 NC_008601.1 197922 198641 R dienelactone hydrolase family protein complement(197922..198641) Francisella tularensis subsp. novicida U112 4547417 YP_897845.1 CDS FTN_0181 NC_008601.1 198739 199581 R manganese/zinc/iron chelate uptake transporter (MZT) family protein complement(198739..199581) Francisella tularensis subsp. novicida U112 4547418 YP_897846.1 CDS FTN_0182 NC_008601.1 199523 200200 R ATP-binding cassette (ABC) superfamily protein complement(199523..200200) Francisella tularensis subsp. novicida U112 4547419 YP_897847.1 CDS FTN_0183 NC_008601.1 200202 201119 R periplasmic solute binding family protein complement(200202..201119) Francisella tularensis subsp. novicida U112 4547420 YP_897848.1 CDS FTN_0184 NC_008601.1 201194 202417 R major facilitator transporter complement(201194..202417) Francisella tularensis subsp. novicida U112 4547421 YP_897849.1 CDS FTN_0185 NC_008601.1 202538 203002 R outer membrane lipoprotein complement(202538..203002) Francisella tularensis subsp. novicida U112 4547422 YP_897850.1 CDS wrbA NC_008601.1 203013 203609 R trp repressor binding protein complement(203013..203609) Francisella tularensis subsp. novicida U112 4547423 YP_897851.1 CDS rbn NC_008601.1 203616 204812 D tRNA processing ribonuclease BN 203616..204812 Francisella tularensis subsp. novicida U112 4547424 YP_897852.1 CDS FTN_0188 NC_008601.1 204831 205406 D nicotinamide ribonucleoside (NR) uptake permease (PnuC) family protein 204831..205406 Francisella tularensis subsp. novicida U112 4547425 YP_897853.1 CDS priA NC_008601.1 205403 207556 D primosomal protein N 205403..207556 Francisella tularensis subsp. novicida U112 4547426 YP_897854.1 CDS FTN_0190 NC_008601.1 207623 208801 R drug:H+ antiporter-1 (DHA1) family protein complement(207623..208801) Francisella tularensis subsp. novicida U112 4547427 YP_897855.1 CDS FTN_0191 NC_008601.1 208869 209609 R polar amino acid uptake transporter complement(208869..209609) Francisella tularensis subsp. novicida U112 4547428 YP_897856.1 CDS cydB NC_008601.1 209802 210995 R cytochrome bd-I terminal oxidase subunit II complement(209802..210995) Francisella tularensis subsp. novicida U112 4547429 YP_897857.1 CDS cydA NC_008601.1 211006 212760 R cytochrome bd-I terminal oxidase subunit I complement(211006..212760) Francisella tularensis subsp. novicida U112 4547430 YP_897858.1 CDS FTN_0194 NC_008601.1 213217 214584 R major facilitator transporter complement(213217..214584) Francisella tularensis subsp. novicida U112 4547431 YP_897859.1 CDS cyoA NC_008601.1 216593 217495 D cytochrome bo terminal oxidase subunit II 216593..217495 Francisella tularensis subsp. novicida U112 4547432 YP_897860.1 CDS cyoB NC_008601.1 217534 219564 D cytochrome bo terminal oxidase subunit I 217534..219564 Francisella tularensis subsp. novicida U112 4547433 YP_897861.1 CDS cyoC NC_008601.1 219561 220163 D cytochrome bo terminal oxidase subunit III 219561..220163 Francisella tularensis subsp. novicida U112 4547434 YP_897862.1 CDS cyoD NC_008601.1 220165 220497 D cytochrome bo terminal oxidase subunit IV 220165..220497 Francisella tularensis subsp. novicida U112 4547550 YP_897863.1 CDS cyoE NC_008601.1 220528 221376 D converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 220528..221376 Francisella tularensis subsp. novicida U112 4547551 YP_897864.1 CDS FTN_0200 NC_008601.1 221521 222564 R UDP-3-O-[3-fatty acid] glucosamine N-acyltransferase complement(221521..222564) Francisella tularensis subsp. novicida U112 4547552 YP_897865.1 CDS FTN_0201 NC_008601.1 222639 223334 R hypothetical protein complement(222639..223334) Francisella tularensis subsp. novicida U112 4547553 YP_897866.1 CDS pdxY NC_008601.1 223334 224185 R pyridoxal kinase complement(223334..224185) Francisella tularensis subsp. novicida U112 4547554 YP_897867.1 CDS FTN_0203 NC_008601.1 224192 224626 R hypothetical protein complement(224192..224626) Francisella tularensis subsp. novicida U112 4547555 YP_897868.1 CDS FTN_0204 NC_008601.1 224772 225728 D methanol dehydrogenase regulatory protein 224772..225728 Francisella tularensis subsp. novicida U112 4547556 YP_897869.1 CDS FTN_0205 NC_008601.1 225741 226652 D hypothetical protein 225741..226652 Francisella tularensis subsp. novicida U112 4547557 YP_897870.1 CDS FTN_0206 NC_008601.1 226642 227118 D hypothetical protein 226642..227118 Francisella tularensis subsp. novicida U112 4547558 YP_897871.1 CDS FTN_0207 NC_008601.1 227115 228116 D von Willebrand factor type A domain-containing protein 227115..228116 Francisella tularensis subsp. novicida U112 4547559 YP_897872.1 CDS FTN_0208 NC_008601.1 228118 229116 D hypothetical protein 228118..229116 Francisella tularensis subsp. novicida U112 4547560 YP_897873.1 CDS FTN_0209 NC_008601.1 229107 229976 D hypothetical protein 229107..229976 Francisella tularensis subsp. novicida U112 4547561 YP_897874.1 CDS FTN_0210 NC_008601.1 229966 231591 D hypothetical protein 229966..231591 Francisella tularensis subsp. novicida U112 4547562 YP_897875.1 CDS pcp NC_008601.1 231598 232266 D pyrrolidone carboxylylate peptidase 231598..232266 Francisella tularensis subsp. novicida U112 4547563 YP_897876.1 CDS FTN_0212 NC_008601.1 232274 232756 D putative cytochrome c-type biogenesis protein 232274..232756 Francisella tularensis subsp. novicida U112 4547564 YP_897877.1 CDS holC NC_008601.1 232787 233227 D DNA polymerase III subunit chi 232787..233227 Francisella tularensis subsp. novicida U112 4547565 YP_897878.1 CDS valS NC_008601.1 234222 236981 D valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 234222..236981 Francisella tularensis subsp. novicida U112 4547566 YP_897879.1 CDS FTN_0215 NC_008601.1 237281 237946 D hypothetical protein 237281..237946 Francisella tularensis subsp. novicida U112 4547567 YP_897880.1 CDS FTN_0216 NC_008601.1 238094 238429 D hypothetical protein 238094..238429 Francisella tularensis subsp. novicida U112 4547568 YP_897881.1 CDS FTN_0217 NC_008601.1 238426 239583 R L-lactate dehydrogenase complement(238426..239583) Francisella tularensis subsp. novicida U112 4547817 YP_897882.1 CDS nfnB NC_008601.1 240473 241126 R catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive; dihydropteridine reductase complement(240473..241126) Francisella tularensis subsp. novicida U112 4547818 YP_897883.1 CDS FTN_0219 NC_008601.1 241266 241643 D MutT/nudix family protein 241266..241643 Francisella tularensis subsp. novicida U112 4547819 YP_897884.1 CDS fumC NC_008601.1 241817 243208 D class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 241817..243208 Francisella tularensis subsp. novicida U112 4547820 YP_897885.1 CDS gltX NC_008601.1 243339 244745 D Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 243339..244745 Francisella tularensis subsp. novicida U112 4547821 YP_897886.1 CDS FTN_0222 NC_008601.1 244745 245713 D hypothetical protein 244745..245713 Francisella tularensis subsp. novicida U112 4547822 YP_897887.1 CDS FTN_0223 NC_008601.1 246583 248121 D amino acid-polyamine-organocation (APC) superfamily protein 246583..248121 Francisella tularensis subsp. novicida U112 4547823 YP_897888.1 CDS FTN_0225 NC_008601.1 248452 249375 R hypothetical protein complement(248452..249375) Francisella tularensis subsp. novicida U112 4547825 YP_897889.1 CDS folA NC_008601.1 249457 249999 R dihydrofolate reductase type I complement(249457..249999) Francisella tularensis subsp. novicida U112 4547826 YP_897890.1 CDS rpsB NC_008601.1 250191 250910 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 250191..250910 Francisella tularensis subsp. novicida U112 4547827 YP_897891.1 CDS tsf NC_008601.1 250932 251801 D EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 250932..251801 Francisella tularensis subsp. novicida U112 4547828 YP_897892.1 CDS pyrH NC_008601.1 251805 252554 D Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 251805..252554 Francisella tularensis subsp. novicida U112 4547829 YP_897893.1 CDS frr NC_008601.1 252583 253140 D Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 252583..253140 Francisella tularensis subsp. novicida U112 4547830 YP_897894.1 CDS uppS NC_008601.1 253173 253946 D catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 253173..253946 Francisella tularensis subsp. novicida U112 4547831 YP_897895.1 CDS cdsA NC_008601.1 253960 254754 D phosphatidate cytidylyltransferase 253960..254754 Francisella tularensis subsp. novicida U112 4547832 YP_897896.1 CDS dut NC_008601.1 254764 255210 D deoxyuridine 5'- triphosphate nucleotidohydrolase; catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 254764..255210 Francisella tularensis subsp. novicida U112 4548386 YP_897897.1 CDS pgsA NC_008601.1 255214 255810 D phosphatidylglycerophosphate synthetase 255214..255810 Francisella tularensis subsp. novicida U112 4548387 YP_897898.1 CDS rpsL NC_008601.1 255945 256319 D interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 255945..256319 Francisella tularensis subsp. novicida U112 4548388 YP_897899.1 CDS rpsG NC_008601.1 256358 256831 D binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 256358..256831 Francisella tularensis subsp. novicida U112 4548389 YP_897900.1 CDS fusA NC_008601.1 256846 258960 D EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 256846..258960 Francisella tularensis subsp. novicida U112 4548390 YP_897901.1 CDS rpsJ NC_008601.1 258981 259298 D NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 258981..259298 Francisella tularensis subsp. novicida U112 4548391 YP_897902.1 CDS rplC NC_008601.1 259402 260034 D binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 259402..260034 Francisella tularensis subsp. novicida U112 4548392 YP_897903.1 CDS rplD NC_008601.1 260067 260690 D L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 260067..260690 Francisella tularensis subsp. novicida U112 4548393 YP_897904.1 CDS rplW NC_008601.1 260687 260986 D binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 260687..260986 Francisella tularensis subsp. novicida U112 4548394 YP_897905.1 CDS rplB NC_008601.1 261008 261832 D one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 261008..261832 Francisella tularensis subsp. novicida U112 4548395 YP_897906.1 CDS rpsS NC_008601.1 261847 262125 D protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 261847..262125 Francisella tularensis subsp. novicida U112 4548396 YP_897907.1 CDS rplV NC_008601.1 262141 262476 D binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 262141..262476 Francisella tularensis subsp. novicida U112 4548397 YP_897908.1 CDS rpsC NC_008601.1 262491 263162 D forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 262491..263162 Francisella tularensis subsp. novicida U112 4548398 YP_897909.1 CDS rplP NC_008601.1 263162 263575 D located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 263162..263575 Francisella tularensis subsp. novicida U112 4548399 YP_897910.1 CDS rpmC NC_008601.1 263575 263775 D one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 263575..263775 Francisella tularensis subsp. novicida U112 4548400 YP_897911.1 CDS rpsQ NC_008601.1 263788 264039 D primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 263788..264039 Francisella tularensis subsp. novicida U112 4548401 YP_897912.1 CDS rplN NC_008601.1 264131 264499 D binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 264131..264499 Francisella tularensis subsp. novicida U112 4548402 YP_897913.1 CDS rplX NC_008601.1 264521 264838 D assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 264521..264838 Francisella tularensis subsp. novicida U112 4548403 YP_897914.1 CDS rplE NC_008601.1 264850 265389 D part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 264850..265389 Francisella tularensis subsp. novicida U112 4548404 YP_897915.1 CDS rpsN NC_008601.1 265408 265713 D located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 265408..265713 Francisella tularensis subsp. novicida U112 4547435 YP_897916.1 CDS rpsH NC_008601.1 265730 266128 D binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 265730..266128 Francisella tularensis subsp. novicida U112 4547436 YP_897917.1 CDS rplF NC_008601.1 266147 266683 D ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 266147..266683 Francisella tularensis subsp. novicida U112 4547437 YP_897918.1 CDS rplR NC_008601.1 266706 267059 D binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 266706..267059 Francisella tularensis subsp. novicida U112 4547438 YP_897919.1 CDS rpsE NC_008601.1 267087 267587 D located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 267087..267587 Francisella tularensis subsp. novicida U112 4547439 YP_897920.1 CDS rpmD NC_008601.1 267594 267779 D L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 267594..267779 Francisella tularensis subsp. novicida U112 4547440 YP_897921.1 CDS rplO NC_008601.1 267786 268217 D late assembly protein; 50S ribosomal protein L15 267786..268217 Francisella tularensis subsp. novicida U112 4547441 YP_897922.1 CDS secY NC_008601.1 268228 269553 D forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 268228..269553 Francisella tularensis subsp. novicida U112 4547442 YP_897923.1 CDS rpmJ NC_008601.1 269577 269690 D smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 269577..269690 Francisella tularensis subsp. novicida U112 4547443 YP_897924.1 CDS rpsM NC_008601.1 269807 270163 D located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 269807..270163 Francisella tularensis subsp. novicida U112 4547444 YP_897925.1 CDS rpsK NC_008601.1 270202 270591 D located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 270202..270591 Francisella tularensis subsp. novicida U112 4547445 YP_897926.1 CDS rpsD NC_008601.1 270613 271233 D primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 270613..271233 Francisella tularensis subsp. novicida U112 4547446 YP_897927.1 CDS rpoA NC_008601.1 271291 272262 D catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 271291..272262 Francisella tularensis subsp. novicida U112 4547447 YP_897928.1 CDS rplQ NC_008601.1 272307 272744 D is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 272307..272744 Francisella tularensis subsp. novicida U112 4547448 YP_897929.1 CDS htpG NC_008601.1 272930 274816 D molecular chaperone; heat shock protein 90 272930..274816 Francisella tularensis subsp. novicida U112 4547449 YP_897930.1 CDS FTN_0267 NC_008601.1 274900 275403 D hypothetical protein 274900..275403 Francisella tularensis subsp. novicida U112 4547450 YP_897931.1 CDS FTN_0269 NC_008601.1 275911 277422 R hypothetical protein complement(275911..277422) Francisella tularensis subsp. novicida U112 4547452 YP_897932.1 CDS pyrG NC_008601.1 277740 279380 D CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 277740..279380 Francisella tularensis subsp. novicida U112 4547453 YP_897933.1 CDS ndk NC_008601.1 279453 279875 D catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 279453..279875 Francisella tularensis subsp. novicida U112 4547454 YP_897934.1 CDS accD NC_008601.1 279916 280818 D acetyl-CoA carboxylase, carboxytransferase subunit beta 279916..280818 Francisella tularensis subsp. novicida U112 4548368 YP_897935.1 CDS folC NC_008601.1 280833 282014 D folylpoly-gamma-glutamate synthetase/ dihydrofolate synthetase 280833..282014 Francisella tularensis subsp. novicida U112 4548369 YP_897936.1 CDS FTN_0274 NC_008601.1 281992 282402 D hypothetical protein 281992..282402 Francisella tularensis subsp. novicida U112 4548370 YP_897937.1 CDS FTN_0275 NC_008601.1 282485 283543 D hypothetical protein 282485..283543 Francisella tularensis subsp. novicida U112 4548371 YP_897938.1 CDS mviN NC_008601.1 283566 285107 D multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) transporter 283566..285107 Francisella tularensis subsp. novicida U112 4548372 YP_897939.1 CDS gshA NC_008601.1 285160 286665 D glutamate-cysteine ligase 285160..286665 Francisella tularensis subsp. novicida U112 4548373 YP_897940.1 CDS rpmE NC_008601.1 286878 287093 R RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(286878..287093) Francisella tularensis subsp. novicida U112 4548374 YP_897941.1 CDS FTN_0279 NC_008601.1 287215 287946 R oxidoreductase complement(287215..287946) Francisella tularensis subsp. novicida U112 4548375 YP_897942.1 CDS FTN_0280 NC_008601.1 288029 288424 D hypothetical protein 288029..288424 Francisella tularensis subsp. novicida U112 4548376 YP_897943.1 CDS FTN_0281 NC_008601.1 288433 288882 D hypothetical protein 288433..288882 Francisella tularensis subsp. novicida U112 4548377 YP_897944.1 CDS FTN_0282 NC_008601.1 288913 289809 D hypothetical protein 288913..289809 Francisella tularensis subsp. novicida U112 4548378 YP_897945.1 CDS FTN_0284 NC_008601.1 291793 292797 D prophage maintenance system killer protein (DOC) 291793..292797 Francisella tularensis subsp. novicida U112 4548380 YP_897946.1 CDS FTN_0285 NC_008601.1 292790 294010 D type I restriction-modification system subunit S 292790..294010 Francisella tularensis subsp. novicida U112 4548381 YP_897947.1 CDS FTN_0286 NC_008601.1 294223 294786 D transposase 294223..294786 Francisella tularensis subsp. novicida U112 4548382 YP_897948.1 CDS FTN_0287 NC_008601.1 294845 295612 D type I restriction-modification system subunit R (restriction) 294845..295612 Francisella tularensis subsp. novicida U112 4548383 YP_897949.1 CDS proQ NC_008601.1 296016 296717 D activator of osmoprotectant transporter ProP 296016..296717 Francisella tularensis subsp. novicida U112 4548385 YP_897950.1 CDS FTN_0290 NC_008601.1 296739 297284 D hypothetical protein 296739..297284 Francisella tularensis subsp. novicida U112 4547681 YP_897951.1 CDS trkH NC_008601.1 297299 298753 R K+ transporter (Trk) family protein complement(297299..298753) Francisella tularensis subsp. novicida U112 4547682 YP_897952.1 CDS FTN_0292 NC_008601.1 298865 299068 D hypothetical protein 298865..299068 Francisella tularensis subsp. novicida U112 4547683 YP_897953.1 CDS lolA NC_008601.1 299467 300084 R lipoprotein releasing system subunit A, outer membrane lipoproteins carrier complement(299467..300084) Francisella tularensis subsp. novicida U112 4547684 YP_897954.1 CDS ftsK NC_008601.1 300085 302586 R cell division protein complement(300085..302586) Francisella tularensis subsp. novicida U112 4547685 YP_897955.1 CDS FTN_0295 NC_008601.1 302708 303376 D phosphatidic acid phosphatase PAP2 superfamily protein 302708..303376 Francisella tularensis subsp. novicida U112 4547686 YP_897956.1 CDS lysP NC_008601.1 303623 305077 D lysine:H+ symporter 303623..305077 Francisella tularensis subsp. novicida U112 4547687 YP_897957.1 CDS FTN_0297 NC_008601.1 305086 305724 D hypothetical protein 305086..305724 Francisella tularensis subsp. novicida U112 4547688 YP_897958.1 CDS glpX NC_008601.1 305744 306730 D type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 305744..306730 Francisella tularensis subsp. novicida U112 4547689 YP_897959.1 CDS putP NC_008601.1 306996 308504 D proline:Na+ symporter 306996..308504 Francisella tularensis subsp. novicida U112 4547690 YP_897960.1 CDS FTN_0300 NC_008601.1 308570 310249 D glycosyl transferase 308570..310249 Francisella tularensis subsp. novicida U112 4547691 YP_897961.1 CDS FTN_0301 NC_008601.1 310260 311567 D HlyC/CorC family transporter-associated protein 310260..311567 Francisella tularensis subsp. novicida U112 4547692 YP_897962.1 CDS FTN_0302 NC_008601.1 311638 311985 D hypothetical protein 311638..311985 Francisella tularensis subsp. novicida U112 4547693 YP_897963.1 CDS FTN_0303 NC_008601.1 311969 312895 D hypothetical protein 311969..312895 Francisella tularensis subsp. novicida U112 4547694 YP_897964.1 CDS FTN_0304 NC_008601.1 312892 314298 D pilus assembly protein 312892..314298 Francisella tularensis subsp. novicida U112 4547695 YP_897965.1 CDS FTN_0305 NC_008601.1 314309 314929 D pilus assembly protein 314309..314929 Francisella tularensis subsp. novicida U112 4547696 YP_897966.1 CDS FTN_0306 NC_008601.1 315040 315717 D pilus assembly protein 315040..315717 Francisella tularensis subsp. novicida U112 4547697 YP_897967.1 CDS FTN_0307 NC_008601.1 315736 316656 D hypothetical protein 315736..316656 Francisella tularensis subsp. novicida U112 4547698 YP_897968.1 CDS FTN_0308 NC_008601.1 316669 318477 D membrane protein 316669..318477 Francisella tularensis subsp. novicida U112 4547699 YP_897969.1 CDS FTN_0309 NC_008601.1 318501 320306 D hypothetical protein 318501..320306 Francisella tularensis subsp. novicida U112 4547700 YP_897970.1 CDS cysS NC_008601.1 320389 321768 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 320389..321768 Francisella tularensis subsp. novicida U112 4548405 YP_897971.1 CDS FTN_0311 NC_008601.1 321772 322716 D involved in methylation of ribosomal protein L3; N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase 321772..322716 Francisella tularensis subsp. novicida U112 4548406 YP_897972.1 CDS FTN_0312 NC_008601.1 322772 323962 D drug:H+ antiporter-1 (DHA1) family protein 322772..323962 Francisella tularensis subsp. novicida U112 4548407 YP_897973.1 CDS FTN_0313 NC_008601.1 323976 324467 D acetyltransferase 323976..324467 Francisella tularensis subsp. novicida U112 4548408 YP_897974.1 CDS FTN_0314 NC_008601.1 324491 324814 R hypothetical protein complement(324491..324814) Francisella tularensis subsp. novicida U112 4548409 YP_897975.1 CDS FTN_0315 NC_008601.1 324845 325591 R traT-like protein complement(324845..325591) Francisella tularensis subsp. novicida U112 4548410 YP_897976.1 CDS FTN_0316 NC_008601.1 325736 326791 R alanine racemase complement(325736..326791) Francisella tularensis subsp. novicida U112 4548411 YP_897977.1 CDS FTN_0317 NC_008601.1 326808 328172 D amino acid transporter 326808..328172 Francisella tularensis subsp. novicida U112 4548412 YP_897978.1 CDS FTN_0318 NC_008601.1 328174 328455 R hypothetical protein complement(328174..328455) Francisella tularensis subsp. novicida U112 4548413 YP_897979.1 CDS FTN_0319 NC_008601.1 328468 329970 R amino acid-polyamine-organocation family protein complement(328468..329970) Francisella tularensis subsp. novicida U112 4548414 YP_897980.1 CDS FTN_0320 NC_008601.1 330336 331079 R hypothetical protein complement(330336..331079) Francisella tularensis subsp. novicida U112 4548415 YP_897981.1 CDS ubiG NC_008601.1 331082 331777 R Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase complement(331082..331777) Francisella tularensis subsp. novicida U112 4548416 YP_897982.1 CDS FTN_0322 NC_008601.1 331919 333019 D VacJ like lipoprotein 331919..333019 Francisella tularensis subsp. novicida U112 4548417 YP_897983.1 CDS FTN_0323 NC_008601.1 333238 333474 R BolA family protein complement(333238..333474) Francisella tularensis subsp. novicida U112 4548418 YP_897984.1 CDS FTN_0324 NC_008601.1 333491 333784 R hypothetical protein complement(333491..333784) Francisella tularensis subsp. novicida U112 4548419 YP_897985.1 CDS FTN_0325 NC_008601.1 333784 334446 R membrane protein complement(333784..334446) Francisella tularensis subsp. novicida U112 4548420 YP_897986.1 CDS FTN_0326 NC_008601.1 334521 335054 R hypothetical protein complement(334521..335054) Francisella tularensis subsp. novicida U112 4548421 YP_897987.1 CDS FTN_0327 NC_008601.1 335054 335818 R ABC-type transport system permease complement(335054..335818) Francisella tularensis subsp. novicida U112 4548422 YP_897988.1 CDS FTN_0328 NC_008601.1 335822 336625 R ABC transporter ATP-binding protein complement(335822..336625) Francisella tularensis subsp. novicida U112 4548423 YP_897989.1 CDS minE NC_008601.1 336639 336911 R works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE complement(336639..336911) Francisella tularensis subsp. novicida U112 4548800 YP_897990.1 CDS minD NC_008601.1 336914 337738 R septum site-determining protein MinD complement(336914..337738) Francisella tularensis subsp. novicida U112 4548801 YP_897991.1 CDS minC NC_008601.1 337778 338464 R septum site-determining protein MinC complement(337778..338464) Francisella tularensis subsp. novicida U112 4548802 YP_897992.1 CDS rpmG NC_008601.1 338499 338654 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 complement(338499..338654) Francisella tularensis subsp. novicida U112 4548803 YP_897993.1 CDS rpmB NC_008601.1 338681 338917 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(338681..338917) Francisella tularensis subsp. novicida U112 4548804 YP_897994.1 CDS FTN_0334 NC_008601.1 339051 339395 R hypothetical protein complement(339051..339395) Francisella tularensis subsp. novicida U112 4548805 YP_897995.1 CDS recG NC_008601.1 339525 341564 D ATP-dependent DNA helicase RecG 339525..341564 Francisella tularensis subsp. novicida U112 4548806 YP_897996.1 CDS FTN_0336 NC_008601.1 341568 341765 D hypothetical protein 341568..341765 Francisella tularensis subsp. novicida U112 4548807 YP_897997.1 CDS fumA NC_008601.1 342333 343847 D fumerate hydratase 342333..343847 Francisella tularensis subsp. novicida U112 4548808 YP_897998.1 CDS FTN_0338 NC_008601.1 344391 345038 D MutT/nudix family protein 344391..345038 Francisella tularensis subsp. novicida U112 4548809 YP_897999.1 CDS FTN_0339 NC_008601.1 345056 345409 D arsenate reductase 345056..345409 Francisella tularensis subsp. novicida U112 4548810 YP_898000.1 CDS FTN_0340 NC_008601.1 345433 345768 R hypothetical protein complement(345433..345768) Francisella tularensis subsp. novicida U112 4548811 YP_898001.1 CDS FTN_0341 NC_008601.1 345945 346190 R hypothetical protein complement(345945..346190) Francisella tularensis subsp. novicida U112 4548812 YP_898002.1 CDS FTN_0342 NC_008601.1 346272 347585 R permease complement(346272..347585) Francisella tularensis subsp. novicida U112 4548813 YP_898003.1 CDS FTN_0343 NC_008601.1 347652 349238 R catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase complement(347652..349238) Francisella tularensis subsp. novicida U112 4548814 YP_898004.1 CDS FTN_0344 NC_008601.1 349251 350966 R aspartate:alanine exchanger (AAE) family protein complement(349251..350966) Francisella tularensis subsp. novicida U112 4548815 YP_898005.1 CDS FTN_0345 NC_008601.1 351041 352147 R SMF family DNA uptake protein complement(351041..352147) Francisella tularensis subsp. novicida U112 4548816 YP_898006.1 CDS FTN_0346 NC_008601.1 352147 353400 R OmpA family protein complement(352147..353400) Francisella tularensis subsp. novicida U112 4548817 YP_898007.1 CDS fkpB NC_008601.1 353592 354056 D FKBP-type peptidyl-prolyl cis-trans isomerase 353592..354056 Francisella tularensis subsp. novicida U112 4548818 YP_898008.1 CDS ispH NC_008601.1 354037 354999 D catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 354037..354999 Francisella tularensis subsp. novicida U112 4548819 YP_898009.1 CDS aroH NC_008601.1 355001 355363 D chorismate mutase 355001..355363 Francisella tularensis subsp. novicida U112 4548330 YP_898010.1 CDS pssA NC_008601.1 355372 356193 D CDP-alcohol phosphatidyltransferase 355372..356193 Francisella tularensis subsp. novicida U112 4548331 YP_898011.1 CDS FTN_0351 NC_008601.1 356198 356422 R hypothetical protein complement(356198..356422) Francisella tularensis subsp. novicida U112 4548332 YP_898012.1 CDS tolQ NC_008601.1 356574 357281 D TolQ protein 356574..357281 Francisella tularensis subsp. novicida U112 4548333 YP_898013.1 CDS tolR NC_008601.1 357297 357737 D TolR protein 357297..357737 Francisella tularensis subsp. novicida U112 4548334 YP_898014.1 CDS tolA NC_008601.1 357724 358635 D group A colicin translocation protein TolA 357724..358635 Francisella tularensis subsp. novicida U112 4548335 YP_898015.1 CDS tolB NC_008601.1 358647 359954 D group A colicin translocation protein TolB 358647..359954 Francisella tularensis subsp. novicida U112 4548336 YP_898016.1 CDS FTN_0356 NC_008601.1 359964 360209 D hypothetical protein 359964..360209 Francisella tularensis subsp. novicida U112 4548337 YP_898017.1 CDS pal NC_008601.1 360228 360851 D OmpA family peptidoglycan-associated lipoprotein 360228..360851 Francisella tularensis subsp. novicida U112 4548338 YP_898018.1 CDS rimO NC_008601.1 360958 362277 D catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase 360958..362277 Francisella tularensis subsp. novicida U112 4548339 YP_898019.1 CDS FTN_0359 NC_008601.1 362380 363102 D short-chain alcohol dehydrogenase 362380..363102 Francisella tularensis subsp. novicida U112 4548340 YP_898020.1 CDS FTN_0360 NC_008601.1 363126 363356 D hypothetical protein 363126..363356 Francisella tularensis subsp. novicida U112 4548341 YP_898021.1 CDS FTN_0361 NC_008601.1 363337 364836 D deoxyribodipyrimidine photolyase 363337..364836 Francisella tularensis subsp. novicida U112 4548342 YP_898022.1 CDS FTN_0362 NC_008601.1 364836 366365 D deoxyribodipyrimidine photolyase-like protein 364836..366365 Francisella tularensis subsp. novicida U112 4548343 YP_898023.1 CDS FTN_0363 NC_008601.1 366625 367554 D sodium bile acid symporter family protein 366625..367554 Francisella tularensis subsp. novicida U112 4548344 YP_898024.1 CDS FTN_0364 NC_008601.1 367604 368227 D hypothetical protein 367604..368227 Francisella tularensis subsp. novicida U112 4548345 YP_898025.1 CDS FTN_0365 NC_008601.1 368251 369009 D hypothetical protein 368251..369009 Francisella tularensis subsp. novicida U112 4548346 YP_898026.1 CDS FTN_0367 NC_008601.1 369322 370557 D phage integrase 369322..370557 Francisella tularensis subsp. novicida U112 4548095 YP_898027.1 CDS FTN_0368 NC_008601.1 371729 372253 D hypothetical protein 371729..372253 Francisella tularensis subsp. novicida U112 4548096 YP_898028.1 CDS FTN_0369 NC_008601.1 372857 373087 D hypothetical protein 372857..373087 Francisella tularensis subsp. novicida U112 4548097 YP_898029.1 CDS FTN_0370 NC_008601.1 373090 373368 D hypothetical protein 373090..373368 Francisella tularensis subsp. novicida U112 4548098 YP_898030.1 CDS FTN_0371 NC_008601.1 373472 374329 D hypothetical protein 373472..374329 Francisella tularensis subsp. novicida U112 4548099 YP_898031.1 CDS FTN_0372 NC_008601.1 374491 374709 D AlpA family regulatory protein 374491..374709 Francisella tularensis subsp. novicida U112 4548100 YP_898032.1 CDS FTN_0373 NC_008601.1 374890 376086 D phage integrase 374890..376086 Francisella tularensis subsp. novicida U112 4548101 YP_898033.1 CDS FTN_0374 NC_008601.1 376108 376317 D hypothetical protein 376108..376317 Francisella tularensis subsp. novicida U112 4548102 YP_898034.1 CDS FTN_0375 NC_008601.1 376636 377253 D hypothetical protein 376636..377253 Francisella tularensis subsp. novicida U112 4548103 YP_898035.1 CDS FTN_0378 NC_008601.1 379010 380464 D hypothetical protein 379010..380464 Francisella tularensis subsp. novicida U112 4548105 YP_898036.1 CDS FTN_0379 NC_008601.1 380755 381129 D hypothetical protein 380755..381129 Francisella tularensis subsp. novicida U112 4548106 YP_898037.1 CDS FTN_0380 NC_008601.1 381374 381619 D hypothetical protein 381374..381619 Francisella tularensis subsp. novicida U112 4548107 YP_898038.1 CDS FTN_0381 NC_008601.1 382197 383183 D hypothetical protein 382197..383183 Francisella tularensis subsp. novicida U112 4548108 YP_898039.1 CDS FTN_0382 NC_008601.1 383357 384595 D arsenite-antimonite (ArsB) efflux family protein 383357..384595 Francisella tularensis subsp. novicida U112 4548109 YP_898040.1 CDS FTN_0383 NC_008601.1 384608 384997 R hypothetical protein complement(384608..384997) Francisella tularensis subsp. novicida U112 4548110 YP_898041.1 CDS FTN_0384 NC_008601.1 385017 385376 R hypothetical protein complement(385017..385376) Francisella tularensis subsp. novicida U112 4548111 YP_898042.1 CDS ubiA NC_008601.1 385390 386244 R UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; 4-hydroxybenzoate polyprenyltransferase complement(385390..386244) Francisella tularensis subsp. novicida U112 4548112 YP_898043.1 CDS ubiC NC_008601.1 386247 386753 R chorismate pyruvate lyase complement(386247..386753) Francisella tularensis subsp. novicida U112 4548113 YP_898044.1 CDS rph NC_008601.1 386852 387559 D RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 386852..387559 Francisella tularensis subsp. novicida U112 4547588 YP_898045.1 CDS FTN_0388 NC_008601.1 387613 387936 R hypothetical protein complement(387613..387936) Francisella tularensis subsp. novicida U112 4547589 YP_898046.1 CDS FTN_0389 NC_008601.1 388041 388991 R Type IV pili, pilus assembly protein complement(388041..388991) Francisella tularensis subsp. novicida U112 4547590 YP_898047.1 CDS htpX NC_008601.1 389096 390163 R putative metalloprotease; heat shock protein HtpX complement(389096..390163) Francisella tularensis subsp. novicida U112 4547591 YP_898048.1 CDS FTN_0391 NC_008601.1 390167 390742 R LemA-like protein complement(390167..390742) Francisella tularensis subsp. novicida U112 4547592 YP_898049.1 CDS FTN_0392 NC_008601.1 390790 391710 R LysR family transcriptional regulator complement(390790..391710) Francisella tularensis subsp. novicida U112 4547593 YP_898050.1 CDS FTN_0393 NC_008601.1 391849 392904 D hypothetical protein 391849..392904 Francisella tularensis subsp. novicida U112 4547594 YP_898051.1 CDS FTN_0394 NC_008601.1 392906 395071 R heavy metal cation transport ATPase complement(392906..395071) Francisella tularensis subsp. novicida U112 4547595 YP_898052.1 CDS FTN_0395 NC_008601.1 395068 395433 R ArsR family transcriptional regulator complement(395068..395433) Francisella tularensis subsp. novicida U112 4547596 YP_898053.1 CDS FTN_0396 NC_008601.1 395576 396229 D hypothetical protein 395576..396229 Francisella tularensis subsp. novicida U112 4547597 YP_898054.1 CDS gpsA NC_008601.1 396549 397547 D catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 396549..397547 Francisella tularensis subsp. novicida U112 4547598 YP_898055.1 CDS FTN_0398 NC_008601.1 397548 398084 R hypothetical protein complement(397548..398084) Francisella tularensis subsp. novicida U112 4547599 YP_898056.1 CDS radA NC_008601.1 398089 399459 R Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA complement(398089..399459) Francisella tularensis subsp. novicida U112 4547600 YP_898057.1 CDS FTN_0400 NC_008601.1 399467 400237 R hypothetical protein complement(399467..400237) Francisella tularensis subsp. novicida U112 4547601 YP_898058.1 CDS FTN_0401 NC_008601.1 400234 400833 R hypothetical protein complement(400234..400833) Francisella tularensis subsp. novicida U112 4547602 YP_898059.1 CDS aroC NC_008601.1 400836 401894 R catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase complement(400836..401894) Francisella tularensis subsp. novicida U112 4547603 YP_898060.1 CDS FTN_0403 NC_008601.1 402035 402688 R hypothetical protein complement(402035..402688) Francisella tularensis subsp. novicida U112 4547604 YP_898061.1 CDS FTN_0404 NC_008601.1 402707 403219 R this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B complement(402707..403219) Francisella tularensis subsp. novicida U112 4547605 YP_898062.1 CDS sodC NC_008601.1 403380 403937 D superoxide dismutase 403380..403937 Francisella tularensis subsp. novicida U112 4547606 YP_898063.1 CDS FTN_0406 NC_008601.1 403941 404732 D sterol desaturase 403941..404732 Francisella tularensis subsp. novicida U112 4547721 YP_898064.1 CDS FTN_0407 NC_008601.1 404707 406101 R amino acid ABC transporter permease complement(404707..406101) Francisella tularensis subsp. novicida U112 4547722 YP_898065.1 CDS FTN_0408 NC_008601.1 406141 406614 D mannose-6-phosphate isomerase 406141..406614 Francisella tularensis subsp. novicida U112 4547723 YP_898066.1 CDS adhC NC_008601.1 406706 407818 D Zn-dependent alcohol dehydrogenase 406706..407818 Francisella tularensis subsp. novicida U112 4547724 YP_898067.1 CDS FTN_0410 NC_008601.1 407867 409057 R catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase complement(407867..409057) Francisella tularensis subsp. novicida U112 4547725 YP_898068.1 CDS FTN_0411 NC_008601.1 409260 410147 D cation transporter 409260..410147 Francisella tularensis subsp. novicida U112 4547726 YP_898069.1 CDS recN NC_008601.1 410233 411882 D DNA repair protein 410233..411882 Francisella tularensis subsp. novicida U112 4547727 YP_898070.1 CDS pilV NC_008601.1 412117 413349 R Type IV pili, pilus assembly protein complement(412117..413349) Francisella tularensis subsp. novicida U112 4547728 YP_898071.1 CDS FTN_0414 NC_008601.1 413582 414019 R Type IV pili, pilus assembly protein complement(413582..414019) Francisella tularensis subsp. novicida U112 4547729 YP_898072.1 CDS pilA NC_008601.1 414149 414556 R Type IV pili, pilus assembly protein complement(414149..414556) Francisella tularensis subsp. novicida U112 4547730 YP_898073.1 CDS lpxE NC_008601.1 414941 415660 D lipid A 1-phosphatase 414941..415660 Francisella tularensis subsp. novicida U112 4547731 YP_898074.1 CDS folD NC_008601.1 415800 416648 D catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 415800..416648 Francisella tularensis subsp. novicida U112 4547732 YP_898075.1 CDS FTN_0418 NC_008601.1 416811 417101 D endonuclease 416811..417101 Francisella tularensis subsp. novicida U112 4547733 YP_898076.1 CDS purM NC_008601.1 417319 418362 D catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 417319..418362 Francisella tularensis subsp. novicida U112 4547734 YP_898077.1 CDS FTN_0420 NC_008601.1 418362 420674 D SAICAR synthetase/phosphoribosylamine-glycine ligase 418362..420674 Francisella tularensis subsp. novicida U112 4547735 YP_898078.1 CDS purN NC_008601.1 420678 421253 D phosphoribosylglycinamide formyltransferase 420678..421253 Francisella tularensis subsp. novicida U112 4547736 YP_898079.1 CDS purE NC_008601.1 421370 421861 D N5-carboxyaminoimidazole ribonucleotide mutase 421370..421861 Francisella tularensis subsp. novicida U112 4547737 YP_898080.1 CDS purK NC_008601.1 421865 422962 D With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 421865..422962 Francisella tularensis subsp. novicida U112 4547738 YP_898081.1 CDS FTN_0424 NC_008601.1 422959 423312 R hypothetical protein complement(422959..423312) Francisella tularensis subsp. novicida U112 4547739 YP_898082.1 CDS prlC NC_008601.1 423393 425399 R oligopeptidase A complement(423393..425399) Francisella tularensis subsp. novicida U112 4547740 YP_898083.1 CDS FTN_0426 NC_008601.1 425491 425862 D hypothetical protein 425491..425862 Francisella tularensis subsp. novicida U112 4548076 YP_898084.1 CDS FTN_0427 NC_008601.1 425944 426393 D hypothetical protein 425944..426393 Francisella tularensis subsp. novicida U112 4548077 YP_898085.1 CDS FTN_0428 NC_008601.1 426551 427030 D hypothetical protein 426551..427030 Francisella tularensis subsp. novicida U112 4548078 YP_898086.1 CDS FTN_0429 NC_008601.1 427130 427633 D hypothetical protein 427130..427633 Francisella tularensis subsp. novicida U112 4548079 YP_898087.1 CDS FTN_0430 NC_008601.1 427666 428133 D hypothetical protein 427666..428133 Francisella tularensis subsp. novicida U112 4548080 YP_898088.1 CDS FTN_0431 NC_008601.1 428206 429648 D hypothetical protein 428206..429648 Francisella tularensis subsp. novicida U112 4548081 YP_898089.1 CDS topA NC_008601.1 429702 431996 R catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining; maintains net negative superhelicity; DNA topoisomerase I complement(429702..431996) Francisella tularensis subsp. novicida U112 4548082 YP_898090.1 CDS parA NC_008601.1 432195 432836 D chmomosome partition protein A 432195..432836 Francisella tularensis subsp. novicida U112 4548083 YP_898091.1 CDS parB NC_008601.1 432829 433743 D chromosome partition protein B 432829..433743 Francisella tularensis subsp. novicida U112 4548084 YP_898092.1 CDS FTN_0435 NC_008601.1 433757 434464 D glutamine amidotransferase 433757..434464 Francisella tularensis subsp. novicida U112 4548085 YP_898093.1 CDS FTN_0436 NC_008601.1 434467 435348 D hypothetical protein 434467..435348 Francisella tularensis subsp. novicida U112 4548086 YP_898094.1 CDS FTN_0437 NC_008601.1 435345 435935 D HD superfamily hydrolase 435345..435935 Francisella tularensis subsp. novicida U112 4548087 YP_898095.1 CDS rrmJ NC_008601.1 435995 436615 R ribosomal large subunit methyltransferase J complement(435995..436615) Francisella tularensis subsp. novicida U112 4548088 YP_898096.1 CDS FTN_0439 NC_008601.1 436773 437240 D hypothetical protein 436773..437240 Francisella tularensis subsp. novicida U112 4548089 YP_898097.1 CDS lspA NC_008601.1 437235 437720 R lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase complement(437235..437720) Francisella tularensis subsp. novicida U112 4548090 YP_898098.1 CDS ileS NC_008601.1 437707 440514 R IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase complement(437707..440514) Francisella tularensis subsp. novicida U112 4548091 YP_898099.1 CDS ribF NC_008601.1 440607 441527 R riboflavin biosynthesis protein RibF complement(440607..441527) Francisella tularensis subsp. novicida U112 4548092 YP_898100.1 CDS maeA NC_008601.1 441678 443492 D malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; malate dehydrogenase 441678..443492 Francisella tularensis subsp. novicida U112 4548093 YP_898101.1 CDS FTN_0444 NC_008601.1 443654 445327 D membrane protein 443654..445327 Francisella tularensis subsp. novicida U112 4548094 YP_898102.1 CDS FTN_0445 NC_008601.1 445344 446789 D hypothetical protein 445344..446789 Francisella tularensis subsp. novicida U112 4548609 YP_898103.1 CDS engA NC_008601.1 446993 448390 D EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 446993..448390 Francisella tularensis subsp. novicida U112 4548610 YP_898104.1 CDS murA NC_008601.1 448359 449663 D UDP-N-acetylglucosamine 1-carboxyvinyltransferase 448359..449663 Francisella tularensis subsp. novicida U112 4548611 YP_898105.1 CDS murB NC_008601.1 449671 450519 D UDP-N-acetylenolpyruvoylglucosamine reductase 449671..450519 Francisella tularensis subsp. novicida U112 4548612 YP_898106.1 CDS FTN_0449 NC_008601.1 450598 451473 D hypothetical protein 450598..451473 Francisella tularensis subsp. novicida U112 4548613 YP_898107.1 CDS FTN_0450 NC_008601.1 451475 452251 R hypothetical protein complement(451475..452251) Francisella tularensis subsp. novicida U112 4548614 YP_898108.1 CDS FTN_0451 NC_008601.1 452274 454379 R signal transduction protein complement(452274..454379) Francisella tularensis subsp. novicida U112 4548615 YP_898109.1 CDS FTN_0452 NC_008601.1 454529 455932 D hypothetical protein 454529..455932 Francisella tularensis subsp. novicida U112 4548616 YP_898110.1 CDS FTN_0453 NC_008601.1 455936 457252 D glycosyl transferase family protein 455936..457252 Francisella tularensis subsp. novicida U112 4548617 YP_898111.1 CDS FTN_0454 NC_008601.1 457266 458282 D hypothetical protein 457266..458282 Francisella tularensis subsp. novicida U112 4548618 YP_898112.1 CDS FTN_0455 NC_008601.1 458374 461274 D CheB methylesterase/CheR methyltransferase 458374..461274 Francisella tularensis subsp. novicida U112 4548619 YP_898113.1 CDS FTN_0456 NC_008601.1 461255 463573 D signal transduction protein 461255..463573 Francisella tularensis subsp. novicida U112 4548620 YP_898114.1 CDS FTN_0457 NC_008601.1 463591 464250 D hypothetical protein 463591..464250 Francisella tularensis subsp. novicida U112 4548621 YP_898115.1 CDS hitA NC_008601.1 464765 465103 R histidine triad (HIT) family protein complement(464765..465103) Francisella tularensis subsp. novicida U112 4548622 YP_898116.1 CDS ubiB NC_008601.1 465109 466767 R 2-octaprenylphenol hydroxylase complement(465109..466767) Francisella tularensis subsp. novicida U112 4548623 YP_898117.1 CDS FTN_0460 NC_008601.1 466760 467347 R hypothetical protein complement(466760..467347) Francisella tularensis subsp. novicida U112 4548624 YP_898118.1 CDS ubiE NC_008601.1 467349 468101 R menaquinone biosynthesis methyltransferase complement(467349..468101) Francisella tularensis subsp. novicida U112 4548625 YP_898119.1 CDS glk NC_008601.1 468195 469211 D glucose kinase 468195..469211 Francisella tularensis subsp. novicida U112 4548626 YP_898120.1 CDS FTN_0463 NC_008601.1 469213 469476 R hypothetical protein complement(469213..469476) Francisella tularensis subsp. novicida U112 4548627 YP_898121.1 CDS FTN_0464 NC_008601.1 469550 470080 R intracellular septation protein A family protein complement(469550..470080) Francisella tularensis subsp. novicida U112 4548628 YP_898122.1 CDS FTN_0465 NC_008601.1 470141 470755 D Sua5/YciO/YrdC family protein 470141..470755 Francisella tularensis subsp. novicida U112 4548224 YP_898123.1 CDS FTN_0466 NC_008601.1 470805 471407 D hypothetical protein 470805..471407 Francisella tularensis subsp. novicida U112 4548225 YP_898124.1 CDS FTN_0467 NC_008601.1 471404 472627 R major facilitator superfamily sugar transporter complement(471404..472627) Francisella tularensis subsp. novicida U112 4548226 YP_898125.1 CDS metG NC_008601.1 472644 474701 R methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase complement(472644..474701) Francisella tularensis subsp. novicida U112 4548227 YP_898126.1 CDS FTN_0471 NC_008601.1 475224 475760 R NADPH-dependent FMN reductase complement(475224..475760) Francisella tularensis subsp. novicida U112 4548230 YP_898127.1 CDS FTN_0477 NC_008601.1 481348 482235 D hypothetical protein 481348..482235 Francisella tularensis subsp. novicida U112 4547455 YP_898128.1 CDS FTN_0478 NC_008601.1 483383 484438 R hypothetical protein complement(483383..484438) Francisella tularensis subsp. novicida U112 4547456 YP_898129.1 CDS FTN_0479 NC_008601.1 484552 485208 R M50B family metallopeptidase complement(484552..485208) Francisella tularensis subsp. novicida U112 4547457 YP_898130.1 CDS FTN_0480 NC_008601.1 486541 486876 D hypothetical protein 486541..486876 Francisella tularensis subsp. novicida U112 4547458 YP_898131.1 CDS psd NC_008601.1 486849 487700 R catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase complement(486849..487700) Francisella tularensis subsp. novicida U112 4547459 YP_898132.1 CDS FTN_0482 NC_008601.1 487800 488780 D hypothetical protein 487800..488780 Francisella tularensis subsp. novicida U112 4547460 YP_898133.1 CDS FTN_0483 NC_008601.1 488789 489832 D NadM-Nudix subfamily; involved in creation of nicotanimide adenine dinucleotide NAD from either biosynthetic or salvage pathways; bifunctional nicotinamide mononucleotide adenylyltransferase/ADP-ribose pyrophosphatase 488789..489832 Francisella tularensis subsp. novicida U112 4547461 YP_898134.1 CDS glmU NC_008601.1 489846 491213 D UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase 489846..491213 Francisella tularensis subsp. novicida U112 4547462 YP_898135.1 CDS glmS NC_008601.1 491234 493072 D Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 491234..493072 Francisella tularensis subsp. novicida U112 4547463 YP_898136.1 CDS FTN_0486 NC_008601.1 493144 493677 D acetyltransferase 493144..493677 Francisella tularensis subsp. novicida U112 4547464 YP_898137.1 CDS rpsU NC_008601.1 493674 493871 R a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 complement(493674..493871) Francisella tularensis subsp. novicida U112 4547465 YP_898138.1 CDS cspC NC_008601.1 493871 494074 R cold shock protein complement(493871..494074) Francisella tularensis subsp. novicida U112 4547466 YP_898139.1 CDS FTN_0489 NC_008601.1 494325 494654 R hypothetical protein complement(494325..494654) Francisella tularensis subsp. novicida U112 4547467 YP_898140.1 CDS map NC_008601.1 494781 495551 D methionine aminopeptidase 494781..495551 Francisella tularensis subsp. novicida U112 4547468 YP_898141.1 CDS FTN_0491 NC_008601.1 495553 496401 D hypothetical protein 495553..496401 Francisella tularensis subsp. novicida U112 4547469 YP_898142.1 CDS parC NC_008601.1 496504 498732 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 496504..498732 Francisella tularensis subsp. novicida U112 4547470 YP_898143.1 CDS mtn NC_008601.1 498729 499415 D enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 498729..499415 Francisella tularensis subsp. novicida U112 4547471 YP_898144.1 CDS FTN_0494 NC_008601.1 499402 500001 R hypothetical protein complement(499402..500001) Francisella tularensis subsp. novicida U112 4547472 YP_898145.1 CDS FTN_0495 NC_008601.1 499994 501112 R BNR/Asp-box repeat-containing protein complement(499994..501112) Francisella tularensis subsp. novicida U112 4547473 YP_898146.1 CDS slt NC_008601.1 501311 503287 D soluble lytic murein transglycosylase 501311..503287 Francisella tularensis subsp. novicida U112 4547663 YP_898147.1 CDS FTN_0497 NC_008601.1 503301 503723 R hypothetical protein complement(503301..503723) Francisella tularensis subsp. novicida U112 4547664 YP_898148.1 CDS FTN_0498 NC_008601.1 504268 505497 D hypothetical protein 504268..505497 Francisella tularensis subsp. novicida U112 4547665 YP_898149.1 CDS dnaE NC_008601.1 505748 509227 D DNA polymerase III subunit alpha 505748..509227 Francisella tularensis subsp. novicida U112 4547666 YP_898150.1 CDS FTN_0500 NC_008601.1 509303 509938 D peptide deformylase 509303..509938 Francisella tularensis subsp. novicida U112 4547667 YP_898151.1 CDS FTN_0502 NC_008601.1 510648 511910 D ABC transporter involved in lipoprotein release, permease component 510648..511910 Francisella tularensis subsp. novicida U112 4547669 YP_898152.1 CDS FTN_0503 NC_008601.1 511903 512598 D ABC transporter ATPase 511903..512598 Francisella tularensis subsp. novicida U112 4547670 YP_898153.1 CDS FTN_0504 NC_008601.1 512714 514855 D lysine decarboxylase 512714..514855 Francisella tularensis subsp. novicida U112 4547671 YP_898154.1 CDS gcvT NC_008601.1 514946 516022 D catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 514946..516022 Francisella tularensis subsp. novicida U112 4547672 YP_898155.1 CDS gcvH NC_008601.1 516080 516463 D glycine cleavage system H protein 516080..516463 Francisella tularensis subsp. novicida U112 4547673 YP_898156.1 CDS gcvP1 NC_008601.1 516528 517895 D acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein; glycine dehydrogenase subunit 1 516528..517895 Francisella tularensis subsp. novicida U112 4547674 YP_898157.1 CDS gcvP2 NC_008601.1 517901 519346 D acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein; glycine dehydrogenase subunit 2 517901..519346 Francisella tularensis subsp. novicida U112 4547675 YP_898158.1 CDS FTN_0509 NC_008601.1 519765 523157 D hypothetical protein 519765..523157 Francisella tularensis subsp. novicida U112 4547676 YP_898159.1 CDS FTN_0510 NC_008601.1 523321 523686 D hypothetical protein 523321..523686 Francisella tularensis subsp. novicida U112 4547677 YP_898160.1 CDS FTN_0511 NC_008601.1 523814 524659 R shikimate 5-dehydrogenase complement(523814..524659) Francisella tularensis subsp. novicida U112 4547678 YP_898161.1 CDS glgX NC_008601.1 524685 527897 R pullulanase complement(524685..527897) Francisella tularensis subsp. novicida U112 4547679 YP_898162.1 CDS glgB NC_008601.1 527931 529853 R catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein complement(527931..529853) Francisella tularensis subsp. novicida U112 4547680 YP_898163.1 CDS pgm NC_008601.1 530155 531789 D catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 530155..531789 Francisella tularensis subsp. novicida U112 4547357 YP_898164.1 CDS glgC NC_008601.1 531823 533094 D catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 531823..533094 Francisella tularensis subsp. novicida U112 4547358 YP_898165.1 CDS glgA NC_008601.1 533104 534573 D catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 533104..534573 Francisella tularensis subsp. novicida U112 4547359 YP_898166.1 CDS glgP NC_008601.1 534678 536951 D glycogen phosphorylase 534678..536951 Francisella tularensis subsp. novicida U112 4547360 YP_898167.1 CDS malQ NC_008601.1 536994 538457 D amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase 536994..538457 Francisella tularensis subsp. novicida U112 4547361 YP_898168.1 CDS glyQ NC_008601.1 538549 539439 D glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 538549..539439 Francisella tularensis subsp. novicida U112 4547362 YP_898169.1 CDS murE NC_008601.1 539650 541089 D UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 539650..541089 Francisella tularensis subsp. novicida U112 4547363 YP_898170.1 CDS FTN_0521 NC_008601.1 541170 541529 D hypothetical protein 541170..541529 Francisella tularensis subsp. novicida U112 4547364 YP_898171.1 CDS murF NC_008601.1 541881 543239 D UDP-N--acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate-D-alanyl-D-alanyl ligase 541881..543239 Francisella tularensis subsp. novicida U112 4547365 YP_898172.1 CDS FTN_0523 NC_008601.1 543248 544066 D hypothetical protein 543248..544066 Francisella tularensis subsp. novicida U112 4547366 YP_898173.1 CDS asd NC_008601.1 544116 545216 R catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase complement(544116..545216) Francisella tularensis subsp. novicida U112 4547367 YP_898174.1 CDS thrA NC_008601.1 545312 547732 D aspartate kinase I/homoserine dehydrogenase I 545312..547732 Francisella tularensis subsp. novicida U112 4547368 YP_898175.1 CDS thrB NC_008601.1 547735 548688 D homoserine kinase 547735..548688 Francisella tularensis subsp. novicida U112 4547369 YP_898176.1 CDS thrC NC_008601.1 548701 549990 D catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 548701..549990 Francisella tularensis subsp. novicida U112 4547370 YP_898177.1 CDS lpxH NC_008601.1 550018 550740 R catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine; UDP-2,3-diacylglucosamine hydrolase complement(550018..550740) Francisella tularensis subsp. novicida U112 4547371 YP_898178.1 CDS pyrE NC_008601.1 550730 551356 R involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase complement(550730..551356) Francisella tularensis subsp. novicida U112 4547372 YP_898179.1 CDS mpl NC_008601.1 551516 552886 D UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase 551516..552886 Francisella tularensis subsp. novicida U112 4547373 YP_898180.1 CDS yjfH NC_008601.1 552883 553629 D tRNA/rRNA methyltransferase 552883..553629 Francisella tularensis subsp. novicida U112 4547374 YP_898181.1 CDS FTN_0532 NC_008601.1 553645 554289 R hypothetical protein complement(553645..554289) Francisella tularensis subsp. novicida U112 4547375 YP_898182.1 CDS FTN_0533 NC_008601.1 554319 555512 R drug:H+ antiporter-1 (DHA1) family protein complement(554319..555512) Francisella tularensis subsp. novicida U112 4547376 YP_898183.1 CDS FTN_0534 NC_008601.1 555784 556827 D hypothetical protein 555784..556827 Francisella tularensis subsp. novicida U112 4547511 YP_898184.1 CDS FTN_0535 NC_008601.1 556910 558136 D drug:H+ antiporter-1 (DHA1) family protein 556910..558136 Francisella tularensis subsp. novicida U112 4547512 YP_898185.1 CDS yjjK NC_008601.1 558170 560011 D drug resistance ATPase-1 family protein 558170..560011 Francisella tularensis subsp. novicida U112 4547513 YP_898186.1 CDS FTN_0537 NC_008601.1 560098 561510 D proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter 560098..561510 Francisella tularensis subsp. novicida U112 4547514 YP_898187.1 CDS FTN_0538 NC_008601.1 561535 562995 R hypothetical protein complement(561535..562995) Francisella tularensis subsp. novicida U112 4547515 YP_898188.1 CDS glnS NC_008601.1 563016 564662 R catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase complement(563016..564662) Francisella tularensis subsp. novicida U112 4547516 YP_898189.1 CDS pckA NC_008601.1 564807 566399 D PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 564807..566399 Francisella tularensis subsp. novicida U112 4547517 YP_898190.1 CDS mraY NC_008601.1 566474 567571 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 566474..567571 Francisella tularensis subsp. novicida U112 4547518 YP_898191.1 CDS murD NC_008601.1 567571 568824 D UDP-N-acetylmuramoylalanine--D-glutamate ligase 567571..568824 Francisella tularensis subsp. novicida U112 4547519 YP_898192.1 CDS ftsW NC_008601.1 568834 570039 D cell division protein FtsW 568834..570039 Francisella tularensis subsp. novicida U112 4547520 YP_898193.1 CDS FTN_0544 NC_008601.1 570047 570853 R hypothetical protein complement(570047..570853) Francisella tularensis subsp. novicida U112 4547521 YP_898194.1 CDS FTN_0545 NC_008601.1 570952 571908 D glycosyl transferase 570952..571908 Francisella tularensis subsp. novicida U112 4547522 YP_898195.1 CDS FTN_0546 NC_008601.1 572301 574064 R dolichyl-phosphate-mannose-protein mannosyltransferase family protein complement(572301..574064) Francisella tularensis subsp. novicida U112 4547523 YP_898196.1 CDS FTN_0547 NC_008601.1 574156 574419 R hypothetical protein complement(574156..574419) Francisella tularensis subsp. novicida U112 4547524 YP_898197.1 CDS FTN_0548 NC_008601.1 574440 574754 R hypothetical protein complement(574440..574754) Francisella tularensis subsp. novicida U112 4547525 YP_898198.1 CDS sspA NC_008601.1 574840 575472 D stringent starvation protein A 574840..575472 Francisella tularensis subsp. novicida U112 4547526 YP_898199.1 CDS sohB NC_008601.1 575484 576500 D SohB; periplasmic protein; member of the peptidase S49 family; putative periplasmic protease 575484..576500 Francisella tularensis subsp. novicida U112 4547527 YP_898200.1 CDS holB NC_008601.1 576508 577419 D DNA polymerase III, delta prime subunit 576508..577419 Francisella tularensis subsp. novicida U112 4547528 YP_898201.1 CDS yhbY NC_008601.1 577430 577708 D RNA-binding protein 577430..577708 Francisella tularensis subsp. novicida U112 4547529 YP_898202.1 CDS hemB NC_008601.1 577716 578690 D catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 577716..578690 Francisella tularensis subsp. novicida U112 4548458 YP_898203.1 CDS FTN_0554 NC_008601.1 578694 579161 D RNA methyltransferase 578694..579161 Francisella tularensis subsp. novicida U112 4548459 YP_898204.1 CDS ansB NC_008601.1 579267 580331 D periplasmic L-asparaginase II 579267..580331 Francisella tularensis subsp. novicida U112 4548460 YP_898205.1 CDS FTN_0556 NC_008601.1 580679 581242 D hypothetical protein 580679..581242 Francisella tularensis subsp. novicida U112 4548461 YP_898206.1 CDS argS NC_008601.1 581293 583038 R catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase complement(581293..583038) Francisella tularensis subsp. novicida U112 4548462 YP_898207.1 CDS ostA1 NC_008601.1 583164 585770 D organic solvent tolerance protein, OstA 583164..585770 Francisella tularensis subsp. novicida U112 4548463 YP_898208.1 CDS FTN_0559 NC_008601.1 585770 587179 D peptidyl-prolyl cis-trans isomerase 585770..587179 Francisella tularensis subsp. novicida U112 4548464 YP_898209.1 CDS ksgA NC_008601.1 587181 587969 D catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 587181..587969 Francisella tularensis subsp. novicida U112 4548465 YP_898210.1 CDS apaH NC_008601.1 587981 588808 D hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 587981..588808 Francisella tularensis subsp. novicida U112 4548466 YP_898211.1 CDS aroD NC_008601.1 588812 589249 D catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 588812..589249 Francisella tularensis subsp. novicida U112 4548467 YP_898212.1 CDS accB NC_008601.1 589254 589736 D acetyl-CoA carboxylase, biotin carboxy carrier protein subunit 589254..589736 Francisella tularensis subsp. novicida U112 4548468 YP_898213.1 CDS accC NC_008601.1 589801 591156 D acetyl-CoA carboxylase, biotin carboxylase subunit 589801..591156 Francisella tularensis subsp. novicida U112 4548469 YP_898214.1 CDS FTN_0565 NC_008601.1 591250 591930 D hypothetical protein 591250..591930 Francisella tularensis subsp. novicida U112 4548470 YP_898215.1 CDS FTN_0566 NC_008601.1 591956 593074 D mechanosensitive ion channel protein 591956..593074 Francisella tularensis subsp. novicida U112 4548471 YP_898216.1 CDS FTN_0567 NC_008601.1 593079 594002 R tRNA synthetase complement(593079..594002) Francisella tularensis subsp. novicida U112 4548472 YP_898217.1 CDS FTN_0568 NC_008601.1 593999 594781 R birA-like protein complement(593999..594781) Francisella tularensis subsp. novicida U112 4548473 YP_898218.1 CDS recJ NC_008601.1 594778 596520 R single-stranded-DNA-specific exonuclease complement(594778..596520) Francisella tularensis subsp. novicida U112 4548474 YP_898219.1 CDS perM NC_008601.1 596514 597620 R PerM family protein complement(596514..597620) Francisella tularensis subsp. novicida U112 4548475 YP_898220.1 CDS FTN_0571 NC_008601.1 597722 599131 R amino acid-polyamine-organocation (APC) superfamily protein complement(597722..599131) Francisella tularensis subsp. novicida U112 4548476 YP_898221.1 CDS potF NC_008601.1 599215 600396 D putrescine ABC transporter periplasmic protein 599215..600396 Francisella tularensis subsp. novicida U112 4548477 YP_898222.1 CDS FTN_0573 NC_008601.1 600637 601452 R hypothetical protein complement(600637..601452) Francisella tularensis subsp. novicida U112 4547263 YP_898223.1 CDS FTN_0574 NC_008601.1 601671 602558 R GTPase complement(601671..602558) Francisella tularensis subsp. novicida U112 4547264 YP_898224.1 CDS FTN_0575 NC_008601.1 602712 603431 D hypothetical protein 602712..603431 Francisella tularensis subsp. novicida U112 4547265 YP_898225.1 CDS FTN_0576 NC_008601.1 603499 604161 D hypothetical protein 603499..604161 Francisella tularensis subsp. novicida U112 4547266 YP_898226.1 CDS mutL NC_008601.1 604169 605971 D DNA mismatch repair protein 604169..605971 Francisella tularensis subsp. novicida U112 4547267 YP_898227.1 CDS FTN_0578 NC_008601.1 606155 607378 D major facilitator transporter 606155..607378 Francisella tularensis subsp. novicida U112 4547268 YP_898228.1 CDS FTN_0579 NC_008601.1 607385 608659 R major facilitator transporter complement(607385..608659) Francisella tularensis subsp. novicida U112 4547269 YP_898229.1 CDS trxB NC_008601.1 608767 609717 R thioredoxin reductase complement(608767..609717) Francisella tularensis subsp. novicida U112 4547270 YP_898230.1 CDS FTN_0581 NC_008601.1 609808 611025 R phospholipase D complement(609808..611025) Francisella tularensis subsp. novicida U112 4547271 YP_898231.1 CDS gph NC_008601.1 611068 611742 R phosphoglycolate phosphatase complement(611068..611742) Francisella tularensis subsp. novicida U112 4547272 YP_898232.1 CDS FTN_0583 NC_008601.1 611783 612709 R LysR family transcriptional regulator complement(611783..612709) Francisella tularensis subsp. novicida U112 4547273 YP_898233.1 CDS araJ NC_008601.1 612820 613986 D inner membrane protein 612820..613986 Francisella tularensis subsp. novicida U112 4547274 YP_898234.1 CDS cutC NC_008601.1 614001 614723 R copper homeostasis protein CutC family protein complement(614001..614723) Francisella tularensis subsp. novicida U112 4547275 YP_898235.1 CDS FTN_0586 NC_008601.1 615044 615562 D hypothetical protein 615044..615562 Francisella tularensis subsp. novicida U112 4547276 YP_898236.1 CDS FTN_0587 NC_008601.1 615588 616817 D deoxyguanosinetriphosphate triphosphohydrolase 615588..616817 Francisella tularensis subsp. novicida U112 4547277 YP_898237.1 CDS FTN_0588 NC_008601.1 616820 617740 R asparaginase complement(616820..617740) Francisella tularensis subsp. novicida U112 4547278 YP_898238.1 CDS FTN_0589 NC_008601.1 617744 619189 R proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter complement(617744..619189) Francisella tularensis subsp. novicida U112 4547279 YP_898239.1 CDS FTN_0590 NC_008601.1 620283 621503 D hypothetical protein 620283..621503 Francisella tularensis subsp. novicida U112 4547280 YP_898240.1 CDS FTN_0591 NC_008601.1 621627 622667 R hypothetical protein complement(621627..622667) Francisella tularensis subsp. novicida U112 4548950 YP_898241.1 CDS FTN_0592 NC_008601.1 623051 623476 R hypothetical protein complement(623051..623476) Francisella tularensis subsp. novicida U112 4548951 YP_898242.1 CDS sucD NC_008601.1 623588 624460 R succinyl-CoA synthetase, alpha subunit complement(623588..624460) Francisella tularensis subsp. novicida U112 4548952 YP_898243.1 CDS sucC NC_008601.1 624492 625655 R catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta complement(624492..625655) Francisella tularensis subsp. novicida U112 4548953 YP_898244.1 CDS FTN_0595 NC_008601.1 625825 627741 D hypothetical protein 625825..627741 Francisella tularensis subsp. novicida U112 4548954 YP_898245.1 CDS FTN_0596 NC_008601.1 627749 628633 R hypothetical protein complement(627749..628633) Francisella tularensis subsp. novicida U112 4548955 YP_898246.1 CDS FTN_0597 NC_008601.1 628731 629498 D protein-disulfide isomerase 628731..629498 Francisella tularensis subsp. novicida U112 4548956 YP_898247.1 CDS FTN_0598 NC_008601.1 629505 630488 R tRNA-dihydrouridine synthase A complement(629505..630488) Francisella tularensis subsp. novicida U112 4548957 YP_898248.1 CDS FTN_0599 NC_008601.1 630522 631322 R hypothetical protein complement(630522..631322) Francisella tularensis subsp. novicida U112 4548958 YP_898249.1 CDS gyrB NC_008601.1 631504 633915 D DNA gyrase subunit B 631504..633915 Francisella tularensis subsp. novicida U112 4548959 YP_898250.1 CDS FTN_0601 NC_008601.1 634045 634908 D with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS 634045..634908 Francisella tularensis subsp. novicida U112 4548960 YP_898251.1 CDS FTN_0602 NC_008601.1 634911 635450 D with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT 634911..635450 Francisella tularensis subsp. novicida U112 4548961 YP_898252.1 CDS mutM NC_008601.1 635459 636283 R Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase complement(635459..636283) Francisella tularensis subsp. novicida U112 4548962 YP_898253.1 CDS FTN_0604 NC_008601.1 636377 638476 D AMP-binding protein 636377..638476 Francisella tularensis subsp. novicida U112 4548963 YP_898254.1 CDS mraW NC_008601.1 638482 639399 D S-adenosyl-methyltransferase MraW 638482..639399 Francisella tularensis subsp. novicida U112 4548964 YP_898255.1 CDS FTN_0606 NC_008601.1 639396 639746 D hypothetical protein 639396..639746 Francisella tularensis subsp. novicida U112 4548965 YP_898256.1 CDS ftsI NC_008601.1 639739 641433 D cell division protein, peptidoglycan synthetase (PBP) 639739..641433 Francisella tularensis subsp. novicida U112 4548966 YP_898257.1 CDS rpsO NC_008601.1 641539 641805 D primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 641539..641805 Francisella tularensis subsp. novicida U112 4548967 YP_898258.1 CDS pnp NC_008601.1 641862 643943 D polynucleotide phosphorylase/polyadenylase 641862..643943 Francisella tularensis subsp. novicida U112 4548968 YP_898259.1 CDS FTN_0610 NC_008601.1 643949 644299 D essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 643949..644299 Francisella tularensis subsp. novicida U112 4548969 YP_898260.1 CDS kdsA NC_008601.1 644330 645157 D catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 644330..645157 Francisella tularensis subsp. novicida U112 4548188 YP_898261.1 CDS udk NC_008601.1 645168 645833 D functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 645168..645833 Francisella tularensis subsp. novicida U112 4548189 YP_898262.1 CDS rpoZ NC_008601.1 645826 646044 D DNA-directed RNA polymerase subunit K/omega 645826..646044 Francisella tularensis subsp. novicida U112 4548190 YP_898263.1 CDS FTN_0615 NC_008601.1 646311 646883 D hypothetical protein 646311..646883 Francisella tularensis subsp. novicida U112 4548192 YP_898264.1 CDS rumA NC_008601.1 646972 648321 D in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S]; 23S rRNA 5-methyluridine methyltransferase 646972..648321 Francisella tularensis subsp. novicida U112 4548193 YP_898265.1 CDS FTN_0617 NC_008601.1 648331 649296 D ROK family protein 648331..649296 Francisella tularensis subsp. novicida U112 4548194 YP_898266.1 CDS FTN_0618 NC_008601.1 649296 650243 D ROK family protein 649296..650243 Francisella tularensis subsp. novicida U112 4548195 YP_898267.1 CDS FTN_0620 NC_008601.1 651130 652368 D major facilitator transporter 651130..652368 Francisella tularensis subsp. novicida U112 4548197 YP_898268.1 CDS eno NC_008601.1 652477 653847 D enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 652477..653847 Francisella tularensis subsp. novicida U112 4548198 YP_898269.1 CDS ftsB NC_008601.1 653855 654145 D cell division protein, septum formation initiator 653855..654145 Francisella tularensis subsp. novicida U112 4548199 YP_898270.1 CDS ispD NC_008601.1 654135 654824 D 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 654135..654824 Francisella tularensis subsp. novicida U112 4548200 YP_898271.1 CDS FTN_0624 NC_008601.1 654829 656091 R serine permease complement(654829..656091) Francisella tularensis subsp. novicida U112 4548201 YP_898272.1 CDS tdh NC_008601.1 656093 657148 R converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase complement(656093..657148) Francisella tularensis subsp. novicida U112 4548202 YP_898273.1 CDS kbl NC_008601.1 657171 658367 R catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate coenzyme A ligase complement(657171..658367) Francisella tularensis subsp. novicida U112 4548203 YP_898274.1 CDS chiA NC_008601.1 658901 661513 D glycosyl hydrolase family chitinase 658901..661513 Francisella tularensis subsp. novicida U112 4548204 YP_898275.1 CDS upp NC_008601.1 661707 662336 D Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 661707..662336 Francisella tularensis subsp. novicida U112 4548205 YP_898276.1 CDS purU NC_008601.1 662421 663254 D formyltetrahydrofolate deformylase 662421..663254 Francisella tularensis subsp. novicida U112 4547943 YP_898277.1 CDS FTN_0630 NC_008601.1 663345 663689 D hypothetical protein 663345..663689 Francisella tularensis subsp. novicida U112 4547944 YP_898278.1 CDS FTN_0631 NC_008601.1 663750 664970 D metabolite:H+ symporter (MHS) family protein 663750..664970 Francisella tularensis subsp. novicida U112 4547945 YP_898279.1 CDS FTN_0632 NC_008601.1 664954 666279 R dGTP triphosphohydrolase complement(664954..666279) Francisella tularensis subsp. novicida U112 4547946 YP_898280.1 CDS katG NC_008601.1 666383 668602 R peroxidase/catalase complement(666383..668602) Francisella tularensis subsp. novicida U112 4547947 YP_898281.1 CDS FTN_0634 NC_008601.1 668807 669595 R short chain dehydrogenase/reductase family oxidoreductase complement(668807..669595) Francisella tularensis subsp. novicida U112 4547948 YP_898282.1 CDS FTN_0635 NC_008601.1 669589 670983 R serine-type D-Ala-D-Ala carboxypeptidase complement(669589..670983) Francisella tularensis subsp. novicida U112 4547949 YP_898283.1 CDS glpT NC_008601.1 670999 672315 R glycerol-3-phosphate transporter complement(670999..672315) Francisella tularensis subsp. novicida U112 4547950 YP_898284.1 CDS ugpQ NC_008601.1 673286 674314 R glycerophosphoryl diester phosphodiesterase complement(673286..674314) Francisella tularensis subsp. novicida U112 4547951 YP_898285.1 CDS FTN_0638 NC_008601.1 674546 676090 D sulfate permease family protein 674546..676090 Francisella tularensis subsp. novicida U112 4547952 YP_898286.1 CDS FTN_0639 NC_008601.1 676090 676470 D endoribonuclease L-PSP 676090..676470 Francisella tularensis subsp. novicida U112 4547953 YP_898287.1 CDS dctA NC_008601.1 676608 677858 D C4-dicarboxylate transport protein 676608..677858 Francisella tularensis subsp. novicida U112 4547954 YP_898288.1 CDS cydC NC_008601.1 677860 679509 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein complement(677860..679509) Francisella tularensis subsp. novicida U112 4547955 YP_898289.1 CDS cydD NC_008601.1 679506 681287 R in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c; cysteine/glutathione ABC transporter membrane/ATP-binding protein complement(679506..681287) Francisella tularensis subsp. novicida U112 4547956 YP_898290.1 CDS FTN_0643 NC_008601.1 681664 682173 D hypothetical protein 681664..682173 Francisella tularensis subsp. novicida U112 4547957 YP_898291.1 CDS FTN_0644 NC_008601.1 682201 682401 D hypothetical protein 682201..682401 Francisella tularensis subsp. novicida U112 4547958 YP_898292.1 CDS FTN_0645 NC_008601.1 682405 683664 R multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) transporter complement(682405..683664) Francisella tularensis subsp. novicida U112 4547959 YP_898293.1 CDS cscK NC_008601.1 683742 684641 R ROK family protein complement(683742..684641) Francisella tularensis subsp. novicida U112 4547960 YP_898294.1 CDS serS NC_008601.1 684751 686031 R catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase complement(684751..686031) Francisella tularensis subsp. novicida U112 4547961 YP_898295.1 CDS gpmI NC_008601.1 686046 687584 R catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase complement(686046..687584) Francisella tularensis subsp. novicida U112 4547871 YP_898296.1 CDS FTN_0649 NC_008601.1 687803 690835 D 4Fe-4S ferredoxin 687803..690835 Francisella tularensis subsp. novicida U112 4547872 YP_898297.1 CDS cdd NC_008601.1 691032 691433 R cytidine deaminase complement(691032..691433) Francisella tularensis subsp. novicida U112 4547874 YP_898298.1 CDS udp NC_008601.1 691454 692257 R uridine phosphorylase complement(691454..692257) Francisella tularensis subsp. novicida U112 4547875 YP_898299.1 CDS miaE NC_008601.1 692373 692984 D tRNA-(ms(2)io(6)a)-hydroxylase 692373..692984 Francisella tularensis subsp. novicida U112 4547876 YP_898300.1 CDS FTN_0654 NC_008601.1 693036 693686 R hypothetical protein complement(693036..693686) Francisella tularensis subsp. novicida U112 4547877 YP_898301.1 CDS FTN_0655 NC_008601.1 693720 694298 R N6-adenine-specific methylase complement(693720..694298) Francisella tularensis subsp. novicida U112 4547878 YP_898302.1 CDS FTN_0656 NC_008601.1 694299 695522 R zinc-dependent peptidase complement(694299..695522) Francisella tularensis subsp. novicida U112 4547879 YP_898303.1 CDS FTN_0657 NC_008601.1 695529 696782 R M16 family metallopeptidase complement(695529..696782) Francisella tularensis subsp. novicida U112 4547880 YP_898304.1 CDS FTN_0658 NC_008601.1 696790 697851 R membrane protein complement(696790..697851) Francisella tularensis subsp. novicida U112 4547881 YP_898305.1 CDS FTN_0659 NC_008601.1 697851 698933 R membrane protein complement(697851..698933) Francisella tularensis subsp. novicida U112 4547882 YP_898306.1 CDS pepA NC_008601.1 699099 700538 D cytosol aminopeptidase 699099..700538 Francisella tularensis subsp. novicida U112 4547883 YP_898307.1 CDS guaB NC_008601.1 700640 702100 D IMP dehydrogenase/GMP reductase 700640..702100 Francisella tularensis subsp. novicida U112 4547884 YP_898308.1 CDS FTN_0662 NC_008601.1 702166 702819 D thiamine pyrophosphokinase 702166..702819 Francisella tularensis subsp. novicida U112 4547885 YP_898309.1 CDS pgi NC_008601.1 702806 704428 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 702806..704428 Francisella tularensis subsp. novicida U112 4547886 YP_898310.1 CDS fimT NC_008601.1 704429 705013 D Type IV pili, pilus assembly protein 704429..705013 Francisella tularensis subsp. novicida U112 4547887 YP_898311.1 CDS greA NC_008601.1 705047 705529 D necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 705047..705529 Francisella tularensis subsp. novicida U112 4547888 YP_898312.1 CDS uvrA NC_008601.1 705568 708390 D excinuclease ABC subunit A 705568..708390 Francisella tularensis subsp. novicida U112 4548057 YP_898313.1 CDS FTN_0667 NC_008601.1 708396 709784 R drug:H+ antiporter-1 (DHA2) family protein complement(708396..709784) Francisella tularensis subsp. novicida U112 4548058 YP_898314.1 CDS hflB NC_008601.1 709997 711943 D ATP-dependent metalloprotease 709997..711943 Francisella tularensis subsp. novicida U112 4548059 YP_898315.1 CDS deoD NC_008601.1 712184 712906 D purine nucleoside phosphorylase 712184..712906 Francisella tularensis subsp. novicida U112 4548060 YP_898316.1 CDS FTN_0670 NC_008601.1 712903 713352 R hypothetical protein complement(712903..713352) Francisella tularensis subsp. novicida U112 4548061 YP_898317.1 CDS FTN_0671 NC_008601.1 713356 714384 R hypothetical protein complement(713356..714384) Francisella tularensis subsp. novicida U112 4548062 YP_898318.1 CDS secA NC_008601.1 714516 717236 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 714516..717236 Francisella tularensis subsp. novicida U112 4548063 YP_898319.1 CDS tag NC_008601.1 717345 717911 D 3-methyladenine DNA glycosylase 717345..717911 Francisella tularensis subsp. novicida U112 4548064 YP_898320.1 CDS glxK NC_008601.1 717903 719030 R glycerate kinase complement(717903..719030) Francisella tularensis subsp. novicida U112 4548065 YP_898321.1 CDS rplU NC_008601.1 719301 719615 D 50S ribosomal protein L21 719301..719615 Francisella tularensis subsp. novicida U112 4548066 YP_898322.1 CDS rpmA NC_008601.1 719646 719900 D involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 719646..719900 Francisella tularensis subsp. novicida U112 4548067 YP_898323.1 CDS FTN_0677 NC_008601.1 721006 721383 D hypothetical protein 721006..721383 Francisella tularensis subsp. novicida U112 4548068 YP_898324.1 CDS FTN_0678 NC_008601.1 721380 722594 R drug:H+ antiporter-1 (DHA1) family protein complement(721380..722594) Francisella tularensis subsp. novicida U112 4548069 YP_898325.1 CDS rnd NC_008601.1 722623 723717 R ribonuclease D complement(722623..723717) Francisella tularensis subsp. novicida U112 4548070 YP_898326.1 CDS uvrC NC_008601.1 723838 725676 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 723838..725676 Francisella tularensis subsp. novicida U112 4548071 YP_898327.1 CDS FTN_0681 NC_008601.1 725743 726369 D hypothetical protein 725743..726369 Francisella tularensis subsp. novicida U112 4548072 YP_898328.1 CDS FTN_0682 NC_008601.1 726759 726947 D hypothetical protein 726759..726947 Francisella tularensis subsp. novicida U112 4548073 YP_898329.1 CDS kdsB NC_008601.1 726940 727692 D CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 726940..727692 Francisella tularensis subsp. novicida U112 4548074 YP_898330.1 CDS FTN_0684 NC_008601.1 727685 728080 D hypothetical protein 727685..728080 Francisella tularensis subsp. novicida U112 4548075 YP_898331.1 CDS galK NC_008601.1 728077 729225 R galactokinase complement(728077..729225) Francisella tularensis subsp. novicida U112 4547301 YP_898332.1 CDS galT NC_008601.1 729228 730253 R catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P; galactose-1-phosphate uridylyltransferase complement(729228..730253) Francisella tularensis subsp. novicida U112 4547302 YP_898333.1 CDS galP1 NC_008601.1 730344 731726 D major facilitator superfamily galactose-proton symporter 730344..731726 Francisella tularensis subsp. novicida U112 4547303 YP_898334.1 CDS galP2 NC_008601.1 731758 733152 D major facilitator superfamily galactose-proton symporter 731758..733152 Francisella tularensis subsp. novicida U112 4547304 YP_898335.1 CDS ppiC NC_008601.1 733247 733525 D parvulin-like peptidyl-prolyl isomerase domain-containing protein 733247..733525 Francisella tularensis subsp. novicida U112 4547305 YP_898336.1 CDS deaD NC_008601.1 733590 735299 D DEAD/DEAH box helicase 733590..735299 Francisella tularensis subsp. novicida U112 4547306 YP_898337.1 CDS gmk NC_008601.1 735416 735988 D Essential for recycling GMP and indirectly, cGMP; guanylate kinase 735416..735988 Francisella tularensis subsp. novicida U112 4547307 YP_898338.1 CDS nadA NC_008601.1 736009 737034 D 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 736009..737034 Francisella tularensis subsp. novicida U112 4547308 YP_898339.1 CDS nadC NC_008601.1 737043 737906 D nicotinate-nucleotide pyrophosphorylase 737043..737906 Francisella tularensis subsp. novicida U112 4547309 YP_898340.1 CDS nadB NC_008601.1 737909 739396 D L-aspartate oxidase 737909..739396 Francisella tularensis subsp. novicida U112 4547310 YP_898341.1 CDS add NC_008601.1 739415 740455 D deoxyadenosine deaminase/adenosine deaminase 739415..740455 Francisella tularensis subsp. novicida U112 4547311 YP_898342.1 CDS FTN_0696 NC_008601.1 740450 741076 R hypothetical protein complement(740450..741076) Francisella tularensis subsp. novicida U112 4547312 YP_898343.1 CDS FTN_0697 NC_008601.1 741230 741520 D hypothetical protein 741230..741520 Francisella tularensis subsp. novicida U112 4547313 YP_898344.1 CDS FTN_0698 NC_008601.1 741553 742023 D glutathione peroxidase 741553..742023 Francisella tularensis subsp. novicida U112 4547314 YP_898345.1 CDS FTN_0699 NC_008601.1 742065 743231 D hypothetical protein 742065..743231 Francisella tularensis subsp. novicida U112 4547315 YP_898346.1 CDS FTN_0700 NC_008601.1 743228 744298 D hypothetical protein 743228..744298 Francisella tularensis subsp. novicida U112 4547316 YP_898347.1 CDS FTN_0701 NC_008601.1 744311 744958 D hypothetical protein 744311..744958 Francisella tularensis subsp. novicida U112 4547317 YP_898348.1 CDS FTN_0702 NC_008601.1 745266 746768 D hypothetical protein 745266..746768 Francisella tularensis subsp. novicida U112 4547318 YP_898349.1 CDS FTN_0703 NC_008601.1 746848 747420 D type I restriction-modification system subunit S 746848..747420 Francisella tularensis subsp. novicida U112 4547319 YP_898350.1 CDS FTN_0704 NC_008601.1 747676 749163 D type I restriction-modification system subunit M (methyltransferase) 747676..749163 Francisella tularensis subsp. novicida U112 4548780 YP_898351.1 CDS FTN_0705 NC_008601.1 749168 750079 D abortive infection bacteriophage resistance protein 749168..750079 Francisella tularensis subsp. novicida U112 4548781 YP_898352.1 CDS FTN_0706 NC_008601.1 750173 750676 D hypothetical protein 750173..750676 Francisella tularensis subsp. novicida U112 4548782 YP_898353.1 CDS FTN_0707 NC_008601.1 750859 752079 D type I restriction-modification system subunit S 750859..752079 Francisella tularensis subsp. novicida U112 4548783 YP_898354.1 CDS FTN_0708 NC_008601.1 752105 752350 D hypothetical protein 752105..752350 Francisella tularensis subsp. novicida U112 4548784 YP_898355.1 CDS FTN_0709 NC_008601.1 752359 753105 D hypothetical protein 752359..753105 Francisella tularensis subsp. novicida U112 4548785 YP_898356.1 CDS FTN_0710 NC_008601.1 753221 756331 D type I restriction-modification system subunit R (restriction) 753221..756331 Francisella tularensis subsp. novicida U112 4548786 YP_898357.1 CDS FTN_0711 NC_008601.1 756324 756983 D metal-dependent hydrolase 756324..756983 Francisella tularensis subsp. novicida U112 4548787 YP_898358.1 CDS hslR NC_008601.1 757042 757410 R heat shock protein 15 (HSP15) complement(757042..757410) Francisella tularensis subsp. novicida U112 4548788 YP_898359.1 CDS ostA2 NC_008601.1 757650 760250 R organic solvent tolerance protein OstA complement(757650..760250) Francisella tularensis subsp. novicida U112 4548789 YP_898360.1 CDS FTN_0714 NC_008601.1 760571 766129 D hypothetical protein 760571..766129 Francisella tularensis subsp. novicida U112 4548790 YP_898361.1 CDS FTN_0715 NC_008601.1 766940 770710 D hypothetical protein 766940..770710 Francisella tularensis subsp. novicida U112 4548791 YP_898362.1 CDS FTN_0716 NC_008601.1 771325 772140 D hypothetical protein 771325..772140 Francisella tularensis subsp. novicida U112 4548792 YP_898363.1 CDS FTN_0717 NC_008601.1 772240 773937 R hypothetical protein complement(772240..773937) Francisella tularensis subsp. novicida U112 4548793 YP_898364.1 CDS FTN_0718 NC_008601.1 773934 774791 R membrane fusion protein complement(773934..774791) Francisella tularensis subsp. novicida U112 4548794 YP_898365.1 CDS FTN_0719 NC_008601.1 774793 774996 R hypothetical protein complement(774793..774996) Francisella tularensis subsp. novicida U112 4548795 YP_898366.1 CDS FTN_0720 NC_008601.1 775195 775911 D IclR family transcriptional regulator 775195..775911 Francisella tularensis subsp. novicida U112 4548796 YP_898367.1 CDS FTN_0721 NC_008601.1 776065 777051 R hypothetical protein complement(776065..777051) Francisella tularensis subsp. novicida U112 4548797 YP_898368.1 CDS FTN_0722 NC_008601.1 777263 778249 D hypothetical protein 777263..778249 Francisella tularensis subsp. novicida U112 4548798 YP_898369.1 CDS cspA NC_008601.1 778319 778522 R cold shock protein complement(778319..778522) Francisella tularensis subsp. novicida U112 4548799 YP_898370.1 CDS FTN_0724 NC_008601.1 778721 779050 R hypothetical protein complement(778721..779050) Francisella tularensis subsp. novicida U112 4547853 YP_898371.1 CDS rpsU NC_008601.1 779296 779496 D a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 779296..779496 Francisella tularensis subsp. novicida U112 4547854 YP_898372.1 CDS FTN_0727 NC_008601.1 780006 780575 D hypothetical protein 780006..780575 Francisella tularensis subsp. novicida U112 4547856 YP_898373.1 CDS FTN_0728 NC_008601.1 780666 781805 D Co/Zn/Cd cation transporter 780666..781805 Francisella tularensis subsp. novicida U112 4547857 YP_898374.1 CDS galU NC_008601.1 781822 782685 D UTP--glucose-1-phosphate uridylyltransferase 781822..782685 Francisella tularensis subsp. novicida U112 4547858 YP_898375.1 CDS acs NC_008601.1 782807 784744 D acyl-coenzyme A synthetase/AMP-(fatty) acid ligase 782807..784744 Francisella tularensis subsp. novicida U112 4547859 YP_898376.1 CDS FTN_0731 NC_008601.1 784756 785673 D hypothetical protein 784756..785673 Francisella tularensis subsp. novicida U112 4547860 YP_898377.1 CDS FTN_0732 NC_008601.1 785676 785882 R hypothetical protein complement(785676..785882) Francisella tularensis subsp. novicida U112 4547861 YP_898378.1 CDS FTN_0733 NC_008601.1 785967 786260 R hypothetical protein complement(785967..786260) Francisella tularensis subsp. novicida U112 4547862 YP_898379.1 CDS recF NC_008601.1 786282 787331 R RecFOR complex, RecF component complement(786282..787331) Francisella tularensis subsp. novicida U112 4547863 YP_898380.1 CDS FTN_0735 NC_008601.1 787335 788081 R Mg-dependent DNase complement(787335..788081) Francisella tularensis subsp. novicida U112 4547864 YP_898381.1 CDS glyS NC_008601.1 788274 790358 D glycyl-tRNA synthetase subunit beta 788274..790358 Francisella tularensis subsp. novicida U112 4547865 YP_898382.1 CDS potI NC_008601.1 790570 791376 R putrescine ABC transporter membrane protein subunit I complement(790570..791376) Francisella tularensis subsp. novicida U112 4547866 YP_898383.1 CDS potH NC_008601.1 791390 792307 R putrescine ABC transporter membrane protein subunit H complement(791390..792307) Francisella tularensis subsp. novicida U112 4547867 YP_898384.1 CDS potG NC_008601.1 792271 793392 R putrescine ABC transporter ATP-binding protein complement(792271..793392) Francisella tularensis subsp. novicida U112 4547868 YP_898385.1 CDS FTN_0740 NC_008601.1 793798 794058 D hypothetical protein 793798..794058 Francisella tularensis subsp. novicida U112 4547869 YP_898386.1 CDS FTN_0741 NC_008601.1 794171 795628 R proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter complement(794171..795628) Francisella tularensis subsp. novicida U112 4547870 YP_898387.1 CDS serB NC_008601.1 796240 796890 D phosphoserine phosphatase 796240..796890 Francisella tularensis subsp. novicida U112 4548236 YP_898388.1 CDS FTN_0743 NC_008601.1 796879 797901 R hypothetical protein complement(796879..797901) Francisella tularensis subsp. novicida U112 4548237 YP_898389.1 CDS FTN_0744 NC_008601.1 797981 798379 D hypothetical protein 797981..798379 Francisella tularensis subsp. novicida U112 4548238 YP_898390.1 CDS FTN_0745 NC_008601.1 798391 799098 D hypothetical protein 798391..799098 Francisella tularensis subsp. novicida U112 4548239 YP_898391.1 CDS alr NC_008601.1 799235 800332 D alanine racemase 799235..800332 Francisella tularensis subsp. novicida U112 4548240 YP_898392.1 CDS FTN_0747 NC_008601.1 800413 802023 D amino acid-polyamine-organocation (APC) superfamily protein 800413..802023 Francisella tularensis subsp. novicida U112 4548241 YP_898393.1 CDS pheA NC_008601.1 802109 802951 D prephenate dehydratase 802109..802951 Francisella tularensis subsp. novicida U112 4548242 YP_898394.1 CDS FTN_0749 NC_008601.1 802977 803645 D hypothetical protein 802977..803645 Francisella tularensis subsp. novicida U112 4548243 YP_898395.1 CDS sdaA NC_008601.1 803701 805074 D L-serine dehydratase 803701..805074 Francisella tularensis subsp. novicida U112 4548244 YP_898396.1 CDS sufS NC_008601.1 805177 806400 D selenocysteine lyase 805177..806400 Francisella tularensis subsp. novicida U112 4548245 YP_898397.1 CDS FTN_0752 NC_008601.1 806421 806777 D hypothetical protein 806421..806777 Francisella tularensis subsp. novicida U112 4548246 YP_898398.1 CDS FTN_0753 NC_008601.1 806791 807342 D hypothetical protein 806791..807342 Francisella tularensis subsp. novicida U112 4548247 YP_898399.1 CDS coaD NC_008601.1 807354 807842 D Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 807354..807842 Francisella tularensis subsp. novicida U112 4548248 YP_898400.1 CDS FTN_0755 NC_008601.1 807847 808092 D 4Fe-4S ferredoxin 807847..808092 Francisella tularensis subsp. novicida U112 4548249 YP_898401.1 CDS fopA NC_008601.1 808202 809380 D OmpA family protein 808202..809380 Francisella tularensis subsp. novicida U112 4548250 YP_898402.1 CDS FTN_0757 NC_008601.1 810052 814941 D membrane protein 810052..814941 Francisella tularensis subsp. novicida U112 4548251 YP_898403.1 CDS FTN_0758 NC_008601.1 814922 815878 D hypothetical protein 814922..815878 Francisella tularensis subsp. novicida U112 4548252 YP_898404.1 CDS FTN_0759 NC_008601.1 816036 816329 D hypothetical protein 816036..816329 Francisella tularensis subsp. novicida U112 4548253 YP_898405.1 CDS FTN_0760 NC_008601.1 816310 816900 D hypothetical protein 816310..816900 Francisella tularensis subsp. novicida U112 4548254 YP_898406.1 CDS FTN_0761 NC_008601.1 818940 820025 D radical SAM family protein 818940..820025 Francisella tularensis subsp. novicida U112 4548255 YP_898407.1 CDS grxC NC_008601.1 820018 820266 D glutaredoxin like protein 820018..820266 Francisella tularensis subsp. novicida U112 4547569 YP_898408.1 CDS FTN_0763 NC_008601.1 820263 820712 D thioesterase superfamily protein 820263..820712 Francisella tularensis subsp. novicida U112 4547570 YP_898409.1 CDS FTN_0764 NC_008601.1 820725 821078 R hypothetical protein complement(820725..821078) Francisella tularensis subsp. novicida U112 4547571 YP_898410.1 CDS FTN_0765 NC_008601.1 821243 822211 R choloylglycine hydrolase family protein complement(821243..822211) Francisella tularensis subsp. novicida U112 4547572 YP_898411.1 CDS spoU NC_008601.1 822306 823058 R rRNA methyltransferase complement(822306..823058) Francisella tularensis subsp. novicida U112 4547573 YP_898412.1 CDS betT NC_008601.1 823200 825152 D betaine/carnitine/choline transporter (BCCT) family protein 823200..825152 Francisella tularensis subsp. novicida U112 4547574 YP_898413.1 CDS tspO NC_008601.1 825145 825621 R tryptophan-rich sensory protein complement(825145..825621) Francisella tularensis subsp. novicida U112 4547575 YP_898414.1 CDS FTN_0769 NC_008601.1 825750 826604 D this fusion consists of methionine sulfoxide B reductase at the N-terminus and A at the C-terminus; A and B are stereospecific enzymes that recognize the damaged produces of oxidative stress, S and R epimers of methionine sulfoxide, respectively; a fusion protein of these enzymes with thioredoxin provides protection against oxidative stress in Neisseria gonorrhoeae; bifunctional methionine sulfoxide reductase B/A protein 825750..826604 Francisella tularensis subsp. novicida U112 4547576 YP_898415.1 CDS FTN_0770 NC_008601.1 826601 827803 R drug:H+ antiporter-1 (DHA1) family protein complement(826601..827803) Francisella tularensis subsp. novicida U112 4547577 YP_898416.1 CDS FTN_0771 NC_008601.1 828083 829204 R protein-disulfide isomerase complement(828083..829204) Francisella tularensis subsp. novicida U112 4547578 YP_898417.1 CDS FTN_0772 NC_008601.1 829225 829515 R hypothetical protein complement(829225..829515) Francisella tularensis subsp. novicida U112 4547579 YP_898418.1 CDS FTN_0773 NC_008601.1 829603 830691 R 4Fe-4S ferredoxin complement(829603..830691) Francisella tularensis subsp. novicida U112 4547580 YP_898419.1 CDS FTN_0774 NC_008601.1 830694 831029 R hypothetical protein complement(830694..831029) Francisella tularensis subsp. novicida U112 4547581 YP_898420.1 CDS FTN_0775 NC_008601.1 831132 831467 D hypothetical protein 831132..831467 Francisella tularensis subsp. novicida U112 4547582 YP_898421.1 CDS FTN_0776 NC_008601.1 831494 833560 D DNA/RNA helicase superfamily I protein 831494..833560 Francisella tularensis subsp. novicida U112 4547583 YP_898422.1 CDS FTN_0777 NC_008601.1 833557 834003 R hypothetical protein complement(833557..834003) Francisella tularensis subsp. novicida U112 4547584 YP_898423.1 CDS alaS NC_008601.1 834159 836756 D Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 834159..836756 Francisella tularensis subsp. novicida U112 4547585 YP_898424.1 CDS FTN_0779 NC_008601.1 836764 838146 D hypothetical protein 836764..838146 Francisella tularensis subsp. novicida U112 4547586 YP_898425.1 CDS pepB NC_008601.1 838149 839528 D cytosol aminopeptidase 838149..839528 Francisella tularensis subsp. novicida U112 4547587 YP_898426.1 CDS talA NC_008601.1 839608 840627 D transaldolase B 839608..840627 Francisella tularensis subsp. novicida U112 4547320 YP_898427.1 CDS FTN_0782 NC_008601.1 840650 841225 D hypothetical protein 840650..841225 Francisella tularensis subsp. novicida U112 4547321 YP_898428.1 CDS FTN_0783 NC_008601.1 841263 841751 R isochorismatase family protein complement(841263..841751) Francisella tularensis subsp. novicida U112 4547322 YP_898429.1 CDS FTN_0785 NC_008601.1 842439 842945 R isochorismatase family protein complement(842439..842945) Francisella tularensis subsp. novicida U112 4547324 YP_898430.1 CDS FTN_0786 NC_008601.1 843533 844279 D hypothetical protein 843533..844279 Francisella tularensis subsp. novicida U112 4547325 YP_898431.1 CDS rep NC_008601.1 844273 846288 D UvrD/REP superfamily I DNA/RNA helicase 844273..846288 Francisella tularensis subsp. novicida U112 4547326 YP_898432.1 CDS FTN_0788 NC_008601.1 846344 847174 D hypothetical protein 846344..847174 Francisella tularensis subsp. novicida U112 4547327 YP_898433.1 CDS FTN_0789 NC_008601.1 847642 848631 R putative rhodanese, sulfurtransferase complement(847642..848631) Francisella tularensis subsp. novicida U112 4547328 YP_898434.1 CDS rdgC NC_008601.1 848825 849685 D Required for efficient pilin antigenic variation; recombination associated protein 848825..849685 Francisella tularensis subsp. novicida U112 4547329 YP_898435.1 CDS FTN_0791 NC_008601.1 849690 849947 D hypothetical protein 849690..849947 Francisella tularensis subsp. novicida U112 4547330 YP_898436.1 CDS FTN_0792 NC_008601.1 849963 850385 R hypothetical protein complement(849963..850385) Francisella tularensis subsp. novicida U112 4547331 YP_898437.1 CDS FTN_0793 NC_008601.1 850477 851046 D hypothetical protein 850477..851046 Francisella tularensis subsp. novicida U112 4547332 YP_898438.1 CDS FTN_0795 NC_008601.1 852098 852310 R transcriptional regulator complement(852098..852310) Francisella tularensis subsp. novicida U112 4547334 YP_898439.1 CDS FTN_0797 NC_008601.1 853524 854072 D fatty acid hydroxylase 853524..854072 Francisella tularensis subsp. novicida U112 4547336 YP_898440.1 CDS rlmL NC_008601.1 854146 856302 D catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 854146..856302 Francisella tularensis subsp. novicida U112 4547337 YP_898441.1 CDS emrE NC_008601.1 856314 856643 R putative membrane transporter of cations and cationic drugs, multidrug resistance protein complement(856314..856643) Francisella tularensis subsp. novicida U112 4548312 YP_898442.1 CDS FTN_0800 NC_008601.1 857559 858587 R ArsB arsenite/antimonite exporter complement(857559..858587) Francisella tularensis subsp. novicida U112 4548313 YP_898443.1 CDS FTN_0801 NC_008601.1 858597 858947 R ArsR family transcriptional regulator complement(858597..858947) Francisella tularensis subsp. novicida U112 4548314 YP_898444.1 CDS FTN_0802 NC_008601.1 859091 859489 D hypothetical protein 859091..859489 Francisella tularensis subsp. novicida U112 4548315 YP_898445.1 CDS fmt NC_008601.1 859494 860435 D methionyl-tRNA formyltransferase 859494..860435 Francisella tularensis subsp. novicida U112 4548316 YP_898446.1 CDS gshB NC_008601.1 860439 861413 D catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 860439..861413 Francisella tularensis subsp. novicida U112 4548317 YP_898447.1 CDS hemL NC_008601.1 861403 862704 D Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde aminotransferase 861403..862704 Francisella tularensis subsp. novicida U112 4548318 YP_898448.1 CDS FTN_0806 NC_008601.1 862720 864387 R glycosyl hydrolase family protein complement(862720..864387) Francisella tularensis subsp. novicida U112 4548319 YP_898449.1 CDS FTN_0807 NC_008601.1 864448 865230 R short chain dehydrogenase complement(864448..865230) Francisella tularensis subsp. novicida U112 4548320 YP_898450.1 CDS FTN_0808 NC_008601.1 865252 865992 R converts acetoacetate to acetone and carbon dioxide; acetoacetate decarboxylase complement(865252..865992) Francisella tularensis subsp. novicida U112 4548321 YP_898451.1 CDS FTN_0809 NC_008601.1 866270 867520 D fucose: H+ symporter (FHS) family protein 866270..867520 Francisella tularensis subsp. novicida U112 4548322 YP_898452.1 CDS FTN_0810 NC_008601.1 867532 868416 D ROK family protein 867532..868416 Francisella tularensis subsp. novicida U112 4548323 YP_898453.1 CDS birA NC_008601.1 868439 869401 D biotin--acetyl-CoA-carboxylase ligase 868439..869401 Francisella tularensis subsp. novicida U112 4548324 YP_898454.1 CDS bioD NC_008601.1 869344 870021 R dethiobiotin synthetase complement(869344..870021) Francisella tularensis subsp. novicida U112 4548325 YP_898455.1 CDS bioC NC_008601.1 870026 870763 R biotin synthesis protein BioC complement(870026..870763) Francisella tularensis subsp. novicida U112 4548326 YP_898456.1 CDS bioF NC_008601.1 870741 871868 R 8-amino-7-oxononanoate synthase complement(870741..871868) Francisella tularensis subsp. novicida U112 4548327 YP_898457.1 CDS bioB NC_008601.1 871862 872803 R biotin synthase complement(871862..872803) Francisella tularensis subsp. novicida U112 4548328 YP_898458.1 CDS bioA NC_008601.1 872849 874180 D adenosylmethionine-8-amino-7-oxononanoate aminotransferase 872849..874180 Francisella tularensis subsp. novicida U112 4548329 YP_898459.1 CDS FTN_0817 NC_008601.1 874182 874682 R hypothetical protein complement(874182..874682) Francisella tularensis subsp. novicida U112 4547797 YP_898460.1 CDS FTN_0818 NC_008601.1 874698 875618 R lipase/esterase complement(874698..875618) Francisella tularensis subsp. novicida U112 4547798 YP_898461.1 CDS FTN_0819 NC_008601.1 875631 876896 R 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase/dihydropteroate synthase complement(875631..876896) Francisella tularensis subsp. novicida U112 4547799 YP_898462.1 CDS folB NC_008601.1 876898 877251 R dihydroneopterin aldolase complement(876898..877251) Francisella tularensis subsp. novicida U112 4547800 YP_898463.1 CDS FTN_0821 NC_008601.1 877333 878703 D AMP-binding protein 877333..878703 Francisella tularensis subsp. novicida U112 4547801 YP_898464.1 CDS FTN_0822 NC_008601.1 878696 880459 D para-aminobenzoate synthase component I 878696..880459 Francisella tularensis subsp. novicida U112 4547802 YP_898465.1 CDS pabA NC_008601.1 880461 881015 D anthranilate synthase component II 880461..881015 Francisella tularensis subsp. novicida U112 4547803 YP_898466.1 CDS FTN_0824 NC_008601.1 881016 882230 R major facilitator transporter complement(881016..882230) Francisella tularensis subsp. novicida U112 4547804 YP_898467.1 CDS FTN_0825 NC_008601.1 882247 883320 R aldo/keto reductase family protein complement(882247..883320) Francisella tularensis subsp. novicida U112 4547805 YP_898468.1 CDS FTN_0826 NC_008601.1 883399 884463 R aldo/keto reductase family protein complement(883399..884463) Francisella tularensis subsp. novicida U112 4547806 YP_898469.1 CDS FTN_0827 NC_008601.1 884555 885481 R carbon-nitrogen hydrolase family protein complement(884555..885481) Francisella tularensis subsp. novicida U112 4547807 YP_898470.1 CDS FTN_0828 NC_008601.1 885559 885984 R hypothetical protein complement(885559..885984) Francisella tularensis subsp. novicida U112 4547808 YP_898471.1 CDS FTN_0829 NC_008601.1 886123 886842 R hypothetical protein complement(886123..886842) Francisella tularensis subsp. novicida U112 4547809 YP_898472.1 CDS folE NC_008601.1 886832 887452 R involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I complement(886832..887452) Francisella tularensis subsp. novicida U112 4547810 YP_898473.1 CDS FTN_0831 NC_008601.1 887579 888904 D ATP-dependent RNA helicase 887579..888904 Francisella tularensis subsp. novicida U112 4547811 YP_898474.1 CDS FTN_0832 NC_008601.1 888901 890442 R proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter complement(888901..890442) Francisella tularensis subsp. novicida U112 4547812 YP_898475.1 CDS FTN_0833 NC_008601.1 890580 890900 R hypothetical protein complement(890580..890900) Francisella tularensis subsp. novicida U112 4547813 YP_898476.1 CDS gor NC_008601.1 890911 892272 R catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase complement(890911..892272) Francisella tularensis subsp. novicida U112 4547814 YP_898477.1 CDS FTN_0835 NC_008601.1 892308 893027 R hypothetical protein complement(892308..893027) Francisella tularensis subsp. novicida U112 4547815 YP_898478.1 CDS FTN_0836 NC_008601.1 893027 893530 R kinase-like protein complement(893027..893530) Francisella tularensis subsp. novicida U112 4547816 YP_898479.1 CDS FTN_0837 NC_008601.1 893530 894228 R hypothetical protein complement(893530..894228) Francisella tularensis subsp. novicida U112 4548629 YP_898480.1 CDS xthA NC_008601.1 894229 895017 R exodeoxyribonuclease III complement(894229..895017) Francisella tularensis subsp. novicida U112 4548630 YP_898481.1 CDS FTN_0839 NC_008601.1 895194 896294 D hypothetical protein 895194..896294 Francisella tularensis subsp. novicida U112 4548631 YP_898482.1 CDS mdaB NC_008601.1 896313 896903 D NADPH-quinone reductase 896313..896903 Francisella tularensis subsp. novicida U112 4548632 YP_898483.1 CDS FTN_0841 NC_008601.1 897004 897681 D ThiJ/PfpI family protein 897004..897681 Francisella tularensis subsp. novicida U112 4548633 YP_898484.1 CDS aroG NC_008601.1 897751 898863 R catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase complement(897751..898863) Francisella tularensis subsp. novicida U112 4548634 YP_898485.1 CDS ffh NC_008601.1 898895 900271 R signal recognition particle GTPase complement(898895..900271) Francisella tularensis subsp. novicida U112 4548635 YP_898486.1 CDS FTN_0844 NC_008601.1 900352 900618 R hypothetical protein complement(900352..900618) Francisella tularensis subsp. novicida U112 4548636 YP_898487.1 CDS FTN_0845 NC_008601.1 900618 901457 R hypothetical protein complement(900618..901457) Francisella tularensis subsp. novicida U112 4548637 YP_898488.1 CDS infA NC_008601.1 901617 901835 D stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 901617..901835 Francisella tularensis subsp. novicida U112 4548638 YP_898489.1 CDS FTN_0847 NC_008601.1 901864 902790 R hypothetical protein complement(901864..902790) Francisella tularensis subsp. novicida U112 4548639 YP_898490.1 CDS FTN_0848 NC_008601.1 902795 904216 R amino acid antiporter complement(902795..904216) Francisella tularensis subsp. novicida U112 4548640 YP_898491.1 CDS trkA NC_008601.1 904275 905648 R involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein complement(904275..905648) Francisella tularensis subsp. novicida U112 4548641 YP_898492.1 CDS FTN_0850 NC_008601.1 905800 906210 D transcriptional regulator 905800..906210 Francisella tularensis subsp. novicida U112 4548642 YP_898493.1 CDS sufB NC_008601.1 906217 907662 D with SufCD activates cysteine desulfurase SufS; cysteine desulfurase activator complex subunit SufB 906217..907662 Francisella tularensis subsp. novicida U112 4548643 YP_898494.1 CDS sufC NC_008601.1 907701 908450 D sufS activator complex, sufC subunit 907701..908450 Francisella tularensis subsp. novicida U112 4548644 YP_898495.1 CDS sufD NC_008601.1 908463 909608 D sufS activator complex, sufD subunit 908463..909608 Francisella tularensis subsp. novicida U112 4548645 YP_898496.1 CDS FTN_0854 NC_008601.1 909700 910482 D hypothetical protein 909700..910482 Francisella tularensis subsp. novicida U112 4548646 YP_898497.1 CDS FTN_0855 NC_008601.1 910576 911265 D hypothetical protein 910576..911265 Francisella tularensis subsp. novicida U112 4548647 YP_898498.1 CDS FTN_0856 NC_008601.1 911269 911595 D thioredoxin 911269..911595 Francisella tularensis subsp. novicida U112 4547224 YP_898499.1 CDS FTN_0857 NC_008601.1 911588 912037 D hypothetical protein 911588..912037 Francisella tularensis subsp. novicida U112 4547225 YP_898500.1 CDS FTN_0858 NC_008601.1 911996 912289 R MarR family transcriptional regulator complement(911996..912289) Francisella tularensis subsp. novicida U112 4547226 YP_898501.1 CDS FTN_0859 NC_008601.1 912293 912898 R hypothetical protein complement(912293..912898) Francisella tularensis subsp. novicida U112 4547227 YP_898502.1 CDS FTN_0860 NC_008601.1 912964 914316 R amino acid transporter (AAT) family protein complement(912964..914316) Francisella tularensis subsp. novicida U112 4547228 YP_898503.1 CDS FTN_0861 NC_008601.1 914550 915791 D hypothetical protein 914550..915791 Francisella tularensis subsp. novicida U112 4547229 YP_898504.1 CDS FTN_0862 NC_008601.1 916124 917248 D hypothetical protein 916124..917248 Francisella tularensis subsp. novicida U112 4547230 YP_898505.1 CDS FTN_0863 NC_008601.1 917341 917778 D hypothetical protein 917341..917778 Francisella tularensis subsp. novicida U112 4547231 YP_898506.1 CDS FTN_0864 NC_008601.1 918329 918700 D hypothetical protein 918329..918700 Francisella tularensis subsp. novicida U112 4547232 YP_898507.1 CDS mutT NC_008601.1 918872 919291 R mutator protein complement(918872..919291) Francisella tularensis subsp. novicida U112 4547233 YP_898508.1 CDS FTN_0866 NC_008601.1 919330 919914 D hypothetical protein 919330..919914 Francisella tularensis subsp. novicida U112 4547234 YP_898509.1 CDS FTN_0867 NC_008601.1 919916 920326 D hypothetical protein 919916..920326 Francisella tularensis subsp. novicida U112 4547235 YP_898510.1 CDS FTN_0868 NC_008601.1 920419 920997 D membrane protein 920419..920997 Francisella tularensis subsp. novicida U112 4547236 YP_898511.1 CDS FTN_0869 NC_008601.1 921132 923027 D hypothetical protein 921132..923027 Francisella tularensis subsp. novicida U112 4547237 YP_898512.1 CDS leuS NC_008601.1 923135 925576 D leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 923135..925576 Francisella tularensis subsp. novicida U112 4547238 YP_898513.1 CDS FTN_0871 NC_008601.1 925584 926159 D rare lipoprotein B family protein 925584..926159 Francisella tularensis subsp. novicida U112 4547239 YP_898514.1 CDS FTN_0872 NC_008601.1 926220 927410 D small conductance mechanosensitive ion channel (MscS) family protein 926220..927410 Francisella tularensis subsp. novicida U112 4547240 YP_898515.1 CDS dcd NC_008601.1 927417 927983 R Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase complement(927417..927983) Francisella tularensis subsp. novicida U112 4547241 YP_898516.1 CDS FTN_0874 NC_008601.1 927995 928855 R nucleotide-binding protein complement(927995..928855) Francisella tularensis subsp. novicida U112 4547242 YP_898517.1 CDS FTN_0875 NC_008601.1 928929 930161 D major facilitator superfamily metabolite/H(+) symporter 928929..930161 Francisella tularensis subsp. novicida U112 4547243 YP_898518.1 CDS FTN_0876 NC_008601.1 930215 931642 D cardiolipin synthase 930215..931642 Francisella tularensis subsp. novicida U112 4548820 YP_898519.1 CDS cls NC_008601.1 931734 933164 D cardiolipin synthetase 931734..933164 Francisella tularensis subsp. novicida U112 4548821 YP_898520.1 CDS FTN_0878 NC_008601.1 933333 934322 D hypothetical protein 933333..934322 Francisella tularensis subsp. novicida U112 4548822 YP_898521.1 CDS FTN_0879 NC_008601.1 934344 935090 R zinc (Zn2+)-iron (Fe2+) permease (ZIP) family protein complement(934344..935090) Francisella tularensis subsp. novicida U112 4548823 YP_898522.1 CDS FTN_0880 NC_008601.1 935093 936310 R hypothetical protein complement(935093..936310) Francisella tularensis subsp. novicida U112 4548824 YP_898523.1 CDS FTN_0881 NC_008601.1 936452 936883 D Fe2+/Zn2+ uptake regulator protein 936452..936883 Francisella tularensis subsp. novicida U112 4548825 YP_898524.1 CDS pheT NC_008601.1 936926 939298 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta complement(936926..939298) Francisella tularensis subsp. novicida U112 4548826 YP_898525.1 CDS pheS NC_008601.1 939318 940331 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha complement(939318..940331) Francisella tularensis subsp. novicida U112 4548827 YP_898526.1 CDS FTN_0884 NC_008601.1 940417 941310 R drug/metabolite transporter superfamily protein complement(940417..941310) Francisella tularensis subsp. novicida U112 4548828 YP_898527.1 CDS FTN_0885 NC_008601.1 941335 942810 R proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter complement(941335..942810) Francisella tularensis subsp. novicida U112 4548829 YP_898528.1 CDS FTN_0886 NC_008601.1 942996 944264 D sugar:cation symporter family protein 942996..944264 Francisella tularensis subsp. novicida U112 4548830 YP_898529.1 CDS FTN_0887 NC_008601.1 944249 945208 R hypothetical protein complement(944249..945208) Francisella tularensis subsp. novicida U112 4548831 YP_898530.1 CDS FTN_0888 NC_008601.1 945336 945872 D hypothetical protein 945336..945872 Francisella tularensis subsp. novicida U112 4548832 YP_898531.1 CDS FTN_0889 NC_008601.1 945887 946090 D transcriptional regulator 945887..946090 Francisella tularensis subsp. novicida U112 4548833 YP_898532.1 CDS FTN_0890 NC_008601.1 946569 947336 D hypothetical protein 946569..947336 Francisella tularensis subsp. novicida U112 4548834 YP_898533.1 CDS ruvB NC_008601.1 947378 948424 R promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB complement(947378..948424) Francisella tularensis subsp. novicida U112 4548835 YP_898534.1 CDS FTN_0892 NC_008601.1 948488 949213 R short chain dehydrogenase family protein complement(948488..949213) Francisella tularensis subsp. novicida U112 4548836 YP_898535.1 CDS FTN_0893 NC_008601.1 949331 949921 D hypothetical protein 949331..949921 Francisella tularensis subsp. novicida U112 4548837 YP_898536.1 CDS FTN_0894 NC_008601.1 949931 950560 R GDSL-like lipolytic enzyme complement(949931..950560) Francisella tularensis subsp. novicida U112 4548838 YP_898537.1 CDS FTN_0895 NC_008601.1 950582 950917 R hypothetical protein complement(950582..950917) Francisella tularensis subsp. novicida U112 4547741 YP_898538.1 CDS dxs NC_008601.1 950933 952780 R catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase complement(950933..952780) Francisella tularensis subsp. novicida U112 4547742 YP_898539.1 CDS guaA NC_008601.1 952862 954412 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(952862..954412) Francisella tularensis subsp. novicida U112 4547743 YP_898540.1 CDS FTN_0898 NC_008601.1 954500 956044 R amino acid permease complement(954500..956044) Francisella tularensis subsp. novicida U112 4547744 YP_898541.1 CDS truA NC_008601.1 956100 956876 R mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A complement(956100..956876) Francisella tularensis subsp. novicida U112 4547745 YP_898542.1 CDS FTN_0900 NC_008601.1 956879 958711 R hypothetical protein complement(956879..958711) Francisella tularensis subsp. novicida U112 4547746 YP_898543.1 CDS FTN_0901 NC_008601.1 958724 959317 R fumarylacetoacetate hydrolase family protein complement(958724..959317) Francisella tularensis subsp. novicida U112 4547747 YP_898544.1 CDS yhbG NC_008601.1 959366 960097 R ABC transporter ATP-binding protein complement(959366..960097) Francisella tularensis subsp. novicida U112 4547748 YP_898545.1 CDS FTN_0903 NC_008601.1 960171 961004 R hypothetical protein complement(960171..961004) Francisella tularensis subsp. novicida U112 4547749 YP_898546.1 CDS FTN_0904 NC_008601.1 960991 961617 R hypothetical protein complement(960991..961617) Francisella tularensis subsp. novicida U112 4547750 YP_898547.1 CDS yrbI NC_008601.1 961625 962173 R 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase complement(961625..962173) Francisella tularensis subsp. novicida U112 4547751 YP_898548.1 CDS ppa NC_008601.1 962264 962785 R inorganic pyrophosphatase complement(962264..962785) Francisella tularensis subsp. novicida U112 4547752 YP_898549.1 CDS FTN_0907 NC_008601.1 962942 964276 D D-alanyl-D-alanine carboxypeptidase 962942..964276 Francisella tularensis subsp. novicida U112 4547753 YP_898550.1 CDS FTN_0908 NC_008601.1 964309 964593 D hypothetical protein 964309..964593 Francisella tularensis subsp. novicida U112 4547754 YP_898551.1 CDS lipB NC_008601.1 964603 965223 D lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 964603..965223 Francisella tularensis subsp. novicida U112 4547755 YP_898552.1 CDS FTN_0910 NC_008601.1 965706 967178 D sugar:cation symporter family protein 965706..967178 Francisella tularensis subsp. novicida U112 4547756 YP_898553.1 CDS FTN_0911 NC_008601.1 967156 969195 D alpha-glucosidase 967156..969195 Francisella tularensis subsp. novicida U112 4547757 YP_898554.1 CDS ndh NC_008601.1 969308 970570 R NADH dehydrogenase complement(969308..970570) Francisella tularensis subsp. novicida U112 4547758 YP_898555.1 CDS rpoD NC_008601.1 970677 972410 R RNA polymerase sigma-70 factor complement(970677..972410) Francisella tularensis subsp. novicida U112 4547759 YP_898556.1 CDS dnaG NC_008601.1 972435 974252 R DNA primase complement(972435..974252) Francisella tularensis subsp. novicida U112 4547760 YP_898557.1 CDS FTN_0915 NC_008601.1 974273 974719 R hypothetical protein complement(974273..974719) Francisella tularensis subsp. novicida U112 4548256 YP_898558.1 CDS rpsU NC_008601.1 974780 974977 R a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 complement(974780..974977) Francisella tularensis subsp. novicida U112 4548257 YP_898559.1 CDS FTN_0917 NC_008601.1 975232 976635 D serine-type D-Ala-D-Ala carboxypeptidase 975232..976635 Francisella tularensis subsp. novicida U112 4548258 YP_898560.1 CDS FTN_0918 NC_008601.1 976636 977247 D hypothetical protein 976636..977247 Francisella tularensis subsp. novicida U112 4548259 YP_898561.1 CDS FTN_0919 NC_008601.1 977263 977679 D hypothetical protein 977263..977679 Francisella tularensis subsp. novicida U112 4548260 YP_898562.1 CDS FTN_0920 NC_008601.1 977672 978475 D TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 977672..978475 Francisella tularensis subsp. novicida U112 4548261 YP_898563.1 CDS FTN_0921 NC_008601.1 978489 979340 D FKBP-type peptidyl-prolyl cis-trans isomerase 978489..979340 Francisella tularensis subsp. novicida U112 4548262 YP_898564.1 CDS ispB NC_008601.1 979358 980335 R octaprenyl diphosphate synthase complement(979358..980335) Francisella tularensis subsp. novicida U112 4548263 YP_898565.1 CDS FTN_0923 NC_008601.1 980424 980855 R hypothetical protein complement(980424..980855) Francisella tularensis subsp. novicida U112 4548264 YP_898566.1 CDS FTN_0924 NC_008601.1 980936 981559 R hypothetical protein complement(980936..981559) Francisella tularensis subsp. novicida U112 4548265 YP_898567.1 CDS FTN_0925 NC_008601.1 982220 983200 R hypothetical protein complement(982220..983200) Francisella tularensis subsp. novicida U112 4548266 YP_898568.1 CDS cysC NC_008601.1 983652 984254 R adenylylsulfate kinase complement(983652..984254) Francisella tularensis subsp. novicida U112 4548267 YP_898569.1 CDS cysN NC_008601.1 984274 985686 R sulfate adenylyltransferase complement(984274..985686) Francisella tularensis subsp. novicida U112 4548268 YP_898570.1 CDS cysD NC_008601.1 988922 989818 R with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 complement(988922..989818) Francisella tularensis subsp. novicida U112 4548269 YP_898571.1 CDS FTN_0929 NC_008601.1 989842 990945 R hypothetical protein complement(989842..990945) Francisella tularensis subsp. novicida U112 4548270 YP_898572.1 CDS FTN_0930 NC_008601.1 990926 991774 R hypothetical protein complement(990926..991774) Francisella tularensis subsp. novicida U112 4548271 YP_898573.1 CDS FTN_0931 NC_008601.1 991793 992752 D hypothetical protein 991793..992752 Francisella tularensis subsp. novicida U112 4548272 YP_898574.1 CDS FTN_0932 NC_008601.1 992752 994551 D ABC transporter ATP-binding protein 992752..994551 Francisella tularensis subsp. novicida U112 4548273 YP_898575.1 CDS FTN_0933 NC_008601.1 994548 994832 D hypothetical protein 994548..994832 Francisella tularensis subsp. novicida U112 4547530 YP_898576.1 CDS FTN_0934 NC_008601.1 994829 995323 D hypothetical protein 994829..995323 Francisella tularensis subsp. novicida U112 4547531 YP_898577.1 CDS asnB NC_008601.1 995336 997189 D asparagine synthase 995336..997189 Francisella tularensis subsp. novicida U112 4547532 YP_898578.1 CDS FTN_0936 NC_008601.1 997186 998418 D hypothetical protein 997186..998418 Francisella tularensis subsp. novicida U112 4547533 YP_898579.1 CDS FTN_0937 NC_008601.1 998435 999337 D hypothetical protein 998435..999337 Francisella tularensis subsp. novicida U112 4547534 YP_898580.1 CDS FTN_0938 NC_008601.1 999435 999626 R hypothetical protein complement(999435..999626) Francisella tularensis subsp. novicida U112 4547535 YP_898581.1 CDS FTN_0939 NC_008601.1 1000019 1000177 R hypothetical protein complement(1000019..1000177) Francisella tularensis subsp. novicida U112 4547536 YP_898582.1 CDS FTN_0940 NC_008601.1 1000693 1000887 R hypothetical protein complement(1000693..1000887) Francisella tularensis subsp. novicida U112 4547537 YP_898583.1 CDS FTN_0941 NC_008601.1 1001160 1001330 R hypothetical protein complement(1001160..1001330) Francisella tularensis subsp. novicida U112 4547538 YP_898584.1 CDS FTN_0942 NC_008601.1 1001367 1001510 R hypothetical protein complement(1001367..1001510) Francisella tularensis subsp. novicida U112 4547539 YP_898585.1 CDS rimI NC_008601.1 1001819 1002259 R ribosomal-protein-alanine acetyltransferase complement(1001819..1002259) Francisella tularensis subsp. novicida U112 4547540 YP_898586.1 CDS FTN_0944 NC_008601.1 1002237 1002662 R hypothetical protein complement(1002237..1002662) Francisella tularensis subsp. novicida U112 4547541 YP_898587.1 CDS rsuA NC_008601.1 1002662 1003477 R 16S rRNA pseudouridine synthase complement(1002662..1003477) Francisella tularensis subsp. novicida U112 4547542 YP_898588.1 CDS pilF NC_008601.1 1003470 1004375 R Type IV pili, pilus assembly protein complement(1003470..1004375) Francisella tularensis subsp. novicida U112 4547543 YP_898589.1 CDS FTN_0947 NC_008601.1 1004365 1005477 R radical SAM superfamily protein complement(1004365..1005477) Francisella tularensis subsp. novicida U112 4547544 YP_898590.1 CDS dnaB NC_008601.1 1005508 1006905 R replicative DNA helicase complement(1005508..1006905) Francisella tularensis subsp. novicida U112 4547545 YP_898591.1 CDS rplI NC_008601.1 1006993 1007448 R in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 complement(1006993..1007448) Francisella tularensis subsp. novicida U112 4547546 YP_898592.1 CDS rpsR NC_008601.1 1007467 1007685 R binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 complement(1007467..1007685) Francisella tularensis subsp. novicida U112 4547547 YP_898593.1 CDS rpsF NC_008601.1 1007701 1008036 R binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 complement(1007701..1008036) Francisella tularensis subsp. novicida U112 4547548 YP_898594.1 CDS FTN_0952 NC_008601.1 1008162 1008644 R hypothetical protein complement(1008162..1008644) Francisella tularensis subsp. novicida U112 4547549 YP_898595.1 CDS hemF NC_008601.1 1008733 1009659 D catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 1008733..1009659 Francisella tularensis subsp. novicida U112 4547244 YP_898596.1 CDS FTN_0954 NC_008601.1 1009684 1010892 D histidine acid phosphatase 1009684..1010892 Francisella tularensis subsp. novicida U112 4547245 YP_898597.1 CDS serC NC_008601.1 1010967 1012019 D catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 1010967..1012019 Francisella tularensis subsp. novicida U112 4547246 YP_898598.1 CDS cmk NC_008601.1 1012006 1012671 D cytidylate kinase 1012006..1012671 Francisella tularensis subsp. novicida U112 4547247 YP_898599.1 CDS FTN_0957 NC_008601.1 1012688 1013299 R short chain dehydrogenase complement(1012688..1013299) Francisella tularensis subsp. novicida U112 4547248 YP_898600.1 CDS FTN_0958 NC_008601.1 1013302 1013826 R AhpC/TSA family protein complement(1013302..1013826) Francisella tularensis subsp. novicida U112 4547249 YP_898601.1 CDS oxyR NC_008601.1 1013924 1014793 D oxidative stress transcriptional regulator 1013924..1014793 Francisella tularensis subsp. novicida U112 4547250 YP_898602.1 CDS FTN_0960 NC_008601.1 1014796 1015527 R hypothetical protein complement(1014796..1015527) Francisella tularensis subsp. novicida U112 4547251 YP_898603.1 CDS FTN_0961 NC_008601.1 1015541 1015813 R hypothetical protein complement(1015541..1015813) Francisella tularensis subsp. novicida U112 4547252 YP_898604.1 CDS FTN_0962 NC_008601.1 1015897 1016691 R hypothetical protein complement(1015897..1016691) Francisella tularensis subsp. novicida U112 4547253 YP_898605.1 CDS FTN_0963 NC_008601.1 1016696 1018192 R NAD-dependent aldehyde dehydrogenase complement(1016696..1018192) Francisella tularensis subsp. novicida U112 4547254 YP_898606.1 CDS FTN_0964 NC_008601.1 1018206 1019321 R dehydrogenase complement(1018206..1019321) Francisella tularensis subsp. novicida U112 4547255 YP_898607.1 CDS FTN_0965 NC_008601.1 1019741 1021150 D metal-dependent exopeptidase 1019741..1021150 Francisella tularensis subsp. novicida U112 4547256 YP_898608.1 CDS FTN_0966 NC_008601.1 1021587 1022996 R hypothetical protein complement(1021587..1022996) Francisella tularensis subsp. novicida U112 4547257 YP_898609.1 CDS vanY NC_008601.1 1022983 1023456 R D-alanyl-D-alanine carboxypeptidase complement(1022983..1023456) Francisella tularensis subsp. novicida U112 4547258 YP_898610.1 CDS dnaQ NC_008601.1 1023450 1024142 R DNA polymerase III subunit epsilon complement(1023450..1024142) Francisella tularensis subsp. novicida U112 4547259 YP_898611.1 CDS FTN_0969 NC_008601.1 1024196 1025695 R hypothetical protein complement(1024196..1025695) Francisella tularensis subsp. novicida U112 4547260 YP_898612.1 CDS FTN_0970 NC_008601.1 1025699 1025914 R hypothetical protein complement(1025699..1025914) Francisella tularensis subsp. novicida U112 4547261 YP_898613.1 CDS phnA NC_008601.1 1025920 1026252 R phosphonoacetate hydrolase complement(1025920..1026252) Francisella tularensis subsp. novicida U112 4547262 YP_898614.1 CDS FTN_0972 NC_008601.1 1026358 1027734 R hypothetical protein complement(1026358..1027734) Francisella tularensis subsp. novicida U112 4547397 YP_898615.1 CDS FTN_0973 NC_008601.1 1027799 1028398 R AhpC/TSA family peroxiredoxin complement(1027799..1028398) Francisella tularensis subsp. novicida U112 4547398 YP_898616.1 CDS FTN_0974 NC_008601.1 1028537 1029118 D haloacid dehalogenase-like hydrolase 1028537..1029118 Francisella tularensis subsp. novicida U112 4547399 YP_898617.1 CDS FTN_0975 NC_008601.1 1029173 1030663 D hypothetical protein 1029173..1030663 Francisella tularensis subsp. novicida U112 4547400 YP_898618.1 CDS FTN_0976 NC_008601.1 1030667 1031410 D ThiF family protein 1030667..1031410 Francisella tularensis subsp. novicida U112 4547401 YP_898619.1 CDS FTN_0977 NC_008601.1 1031487 1032056 D hypothetical protein 1031487..1032056 Francisella tularensis subsp. novicida U112 4547402 YP_898620.1 CDS FTN_0978 NC_008601.1 1032065 1032700 R ubiquinone biosynthesis protein complement(1032065..1032700) Francisella tularensis subsp. novicida U112 4547403 YP_898621.1 CDS FTN_0979 NC_008601.1 1032716 1033228 R major facilitator transporter complement(1032716..1033228) Francisella tularensis subsp. novicida U112 4547404 YP_898622.1 CDS mdh NC_008601.1 1033379 1034338 D Catalyzes the reversible oxidation of malate to oxaloacetate; malate dehydrogenase 1033379..1034338 Francisella tularensis subsp. novicida U112 4547405 YP_898623.1 CDS nrdA NC_008601.1 1034542 1036314 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1034542..1036314 Francisella tularensis subsp. novicida U112 4547406 YP_898624.1 CDS grxA NC_008601.1 1036318 1036578 D glutaredoxin 1036318..1036578 Francisella tularensis subsp. novicida U112 4547407 YP_898625.1 CDS FTN_0983 NC_008601.1 1036585 1037817 D bifunctional gluaredoxin/ribonucleoside-diphosphate reductase subunit beta 1036585..1037817 Francisella tularensis subsp. novicida U112 4547408 YP_898626.1 CDS FTN_0984 NC_008601.1 1037814 1039706 R ABC transporter ATP-binding protein complement(1037814..1039706) Francisella tularensis subsp. novicida U112 4547409 YP_898627.1 CDS FTN_0985 NC_008601.1 1039817 1040419 D DJ-1/PfpI family protein 1039817..1040419 Francisella tularensis subsp. novicida U112 4547410 YP_898628.1 CDS dinP NC_008601.1 1040426 1041475 D involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 1040426..1041475 Francisella tularensis subsp. novicida U112 4547411 YP_898629.1 CDS FTN_0987 NC_008601.1 1042429 1043415 R tRNA-dihydrouridine synthase complement(1042429..1043415) Francisella tularensis subsp. novicida U112 4547412 YP_898630.1 CDS prmA NC_008601.1 1043405 1044250 R 50S ribosomal protein L11 methyltransferase complement(1043405..1044250) Francisella tularensis subsp. novicida U112 4547413 YP_898631.1 CDS yqhD NC_008601.1 1044412 1045569 R Fe-dependent alcohol dehydrogenase complement(1044412..1045569) Francisella tularensis subsp. novicida U112 4547414 YP_898632.1 CDS FTN_0990 NC_008601.1 1045584 1048394 R 4Fe-4S ferredoxin complement(1045584..1048394) Francisella tularensis subsp. novicida U112 4547415 YP_898633.1 CDS lldD NC_008601.1 1048713 1049855 R L-lactate dehydrogenase complement(1048713..1049855) Francisella tularensis subsp. novicida U112 4547416 YP_898634.1 CDS tyrS NC_008601.1 1050287 1051477 R catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase complement(1050287..1051477) Francisella tularensis subsp. novicida U112 4548206 YP_898635.1 CDS lplA NC_008601.1 1051591 1052493 D lipoate-protein ligase A 1051591..1052493 Francisella tularensis subsp. novicida U112 4548207 YP_898636.1 CDS FTN_0994 NC_008601.1 1052496 1053245 R hypothetical protein complement(1052496..1053245) Francisella tularensis subsp. novicida U112 4548208 YP_898637.1 CDS hslV NC_008601.1 1053437 1053988 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 1053437..1053988 Francisella tularensis subsp. novicida U112 4548209 YP_898638.1 CDS hslU NC_008601.1 1053996 1055363 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 1053996..1055363 Francisella tularensis subsp. novicida U112 4548210 YP_898639.1 CDS FTN_0997 NC_008601.1 1056320 1057771 D proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter 1056320..1057771 Francisella tularensis subsp. novicida U112 4548211 YP_898640.1 CDS FTN_0998 NC_008601.1 1057851 1059011 D potassium channel protein 1057851..1059011 Francisella tularensis subsp. novicida U112 4548212 YP_898641.1 CDS udhA NC_008601.1 1059107 1060507 D catalyzes the conversion of NADPH to NADH; soluble pyridine nucleotide transhydrogenase 1059107..1060507 Francisella tularensis subsp. novicida U112 4548213 YP_898642.1 CDS pilD NC_008601.1 1060511 1061359 D Type IV pili leader peptidase and methylase 1060511..1061359 Francisella tularensis subsp. novicida U112 4548214 YP_898643.1 CDS FTN_1001 NC_008601.1 1061369 1062214 D hypothetical protein 1061369..1062214 Francisella tularensis subsp. novicida U112 4548215 YP_898644.1 CDS blaA NC_008601.1 1062223 1063107 D beta-lactamase class A 1062223..1063107 Francisella tularensis subsp. novicida U112 4548216 YP_898645.1 CDS pth NC_008601.1 1063100 1063675 D Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1063100..1063675 Francisella tularensis subsp. novicida U112 4548217 YP_898646.1 CDS ychF NC_008601.1 1063694 1064785 D translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 1063694..1064785 Francisella tularensis subsp. novicida U112 4548218 YP_898647.1 CDS FTN_1005 NC_008601.1 1064800 1065078 D hypothetical protein 1064800..1065078 Francisella tularensis subsp. novicida U112 4548219 YP_898648.1 CDS FTN_1006 NC_008601.1 1065115 1066374 R HlyC/CorC family transporter-associated protein complement(1065115..1066374) Francisella tularensis subsp. novicida U112 4548220 YP_898649.1 CDS rplY NC_008601.1 1066470 1066760 R the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 complement(1066470..1066760) Francisella tularensis subsp. novicida U112 4548221 YP_898650.1 CDS prsA NC_008601.1 1066860 1067828 R ribose-phosphate pyrophosphokinase complement(1066860..1067828) Francisella tularensis subsp. novicida U112 4548222 YP_898651.1 CDS FTN_1009 NC_008601.1 1068039 1069046 D hypothetical protein 1068039..1069046 Francisella tularensis subsp. novicida U112 4548223 YP_898652.1 CDS FTN_1010 NC_008601.1 1069039 1070322 D major facilitator transporter 1069039..1070322 Francisella tularensis subsp. novicida U112 4548292 YP_898653.1 CDS FTN_1011 NC_008601.1 1070329 1071615 R major facilitator superfamily sugar transporter complement(1070329..1071615) Francisella tularensis subsp. novicida U112 4548293 YP_898654.1 CDS FTN_1012 NC_008601.1 1071927 1072760 D small conductance mechanosensitive ion channel family protein 1071927..1072760 Francisella tularensis subsp. novicida U112 4548294 YP_898655.1 CDS FTN_1013 NC_008601.1 1072738 1073913 R monovalent cation:proton antiporter family protein complement(1072738..1073913) Francisella tularensis subsp. novicida U112 4548295 YP_898656.1 CDS FTN_1014 NC_008601.1 1074011 1074643 R nicotinamide ribonucleoside (NR) uptake permease (PnuC) family protein complement(1074011..1074643) Francisella tularensis subsp. novicida U112 4548296 YP_898657.1 CDS FTN_1015 NC_008601.1 1074643 1075146 R isochorismatase family protein complement(1074643..1075146) Francisella tularensis subsp. novicida U112 4548297 YP_898658.1 CDS FTN_1016 NC_008601.1 1075253 1075756 R hypothetical protein complement(1075253..1075756) Francisella tularensis subsp. novicida U112 4548298 YP_898659.1 CDS FTN_1018 NC_008601.1 1076556 1077254 D aldolase/adducin class II family protein 1076556..1077254 Francisella tularensis subsp. novicida U112 4548300 YP_898660.1 CDS hdc NC_008601.1 1077269 1078405 D catalyzes the formation of histamine from L-histidine; histidine decarboxylase 1077269..1078405 Francisella tularensis subsp. novicida U112 4548301 YP_898661.1 CDS FTN_1020 NC_008601.1 1078392 1079204 R hypothetical protein complement(1078392..1079204) Francisella tularensis subsp. novicida U112 4548302 YP_898662.1 CDS FTN_1021 NC_008601.1 1079294 1079830 D hypothetical protein 1079294..1079830 Francisella tularensis subsp. novicida U112 4548303 YP_898663.1 CDS FTN_1022 NC_008601.1 1079866 1080162 D hypothetical protein 1079866..1080162 Francisella tularensis subsp. novicida U112 4548304 YP_898664.1 CDS FTN_1023 NC_008601.1 1080184 1080771 R hypothetical protein complement(1080184..1080771) Francisella tularensis subsp. novicida U112 4548305 YP_898665.1 CDS FTN_1024 NC_008601.1 1080820 1082235 R RmuC family protein complement(1080820..1082235) Francisella tularensis subsp. novicida U112 4548306 YP_898666.1 CDS ruvA NC_008601.1 1082261 1082911 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(1082261..1082911) Francisella tularensis subsp. novicida U112 4548307 YP_898667.1 CDS FTN_1026 NC_008601.1 1082924 1084117 R major facilitator superfamily sugar transporter complement(1082924..1084117) Francisella tularensis subsp. novicida U112 4548308 YP_898668.1 CDS ruvC NC_008601.1 1084199 1084714 R endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase complement(1084199..1084714) Francisella tularensis subsp. novicida U112 4548309 YP_898669.1 CDS FTN_1028 NC_008601.1 1084811 1085557 R hypothetical protein complement(1084811..1085557) Francisella tularensis subsp. novicida U112 4548310 YP_898670.1 CDS FTN_1029 NC_008601.1 1085573 1086232 R isoprenoid biosynthesis protein with amidotransferase-like domain complement(1085573..1086232) Francisella tularensis subsp. novicida U112 4548311 YP_898671.1 CDS lipA NC_008601.1 1086262 1087245 R catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase complement(1086262..1087245) Francisella tularensis subsp. novicida U112 4547962 YP_898672.1 CDS ftnA NC_008601.1 1087455 1087955 D ferric iron binding protein, ferritin-like 1087455..1087955 Francisella tularensis subsp. novicida U112 4547963 YP_898673.1 CDS FTN_1032 NC_008601.1 1087958 1089430 R proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter complement(1087958..1089430) Francisella tularensis subsp. novicida U112 4547964 YP_898674.1 CDS grxB NC_008601.1 1089601 1090245 D cofactor involved in the reduction of disulfides; glutaredoxin 1089601..1090245 Francisella tularensis subsp. novicida U112 4547965 YP_898675.1 CDS rnfB NC_008601.1 1090247 1090876 D iron-sulfur cluster-binding protein 1090247..1090876 Francisella tularensis subsp. novicida U112 4547966 YP_898676.1 CDS nth NC_008601.1 1090869 1091507 D endonuclease III 1090869..1091507 Francisella tularensis subsp. novicida U112 4547967 YP_898677.1 CDS FTN_1036 NC_008601.1 1091504 1091935 D hypothetical protein 1091504..1091935 Francisella tularensis subsp. novicida U112 4547968 YP_898678.1 CDS FTN_1037 NC_008601.1 1091935 1093194 D hypothetical protein 1091935..1093194 Francisella tularensis subsp. novicida U112 4547969 YP_898679.1 CDS FTN_1038 NC_008601.1 1093310 1093996 D hypothetical protein 1093310..1093996 Francisella tularensis subsp. novicida U112 4547970 YP_898680.1 CDS mfd NC_008601.1 1094041 1097466 D transcription-repair coupling factor 1094041..1097466 Francisella tularensis subsp. novicida U112 4547971 YP_898681.1 CDS ilvC NC_008601.1 1097585 1098628 R ketol-acid reductoisomerase complement(1097585..1098628) Francisella tularensis subsp. novicida U112 4547972 YP_898682.1 CDS ilvN NC_008601.1 1098656 1098973 R acetolactate synthase small subunit complement(1098656..1098973) Francisella tularensis subsp. novicida U112 4547973 YP_898683.1 CDS ilvB NC_008601.1 1098978 1100675 R acetolactate synthase large subunit complement(1098978..1100675) Francisella tularensis subsp. novicida U112 4547974 YP_898684.1 CDS ilvD NC_008601.1 1100822 1102504 R catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase complement(1100822..1102504) Francisella tularensis subsp. novicida U112 4547975 YP_898685.1 CDS FTN_1044 NC_008601.1 1102528 1104324 R hypothetical protein complement(1102528..1104324) Francisella tularensis subsp. novicida U112 4547976 YP_898686.1 CDS engB NC_008601.1 1104467 1105060 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(1104467..1105060) Francisella tularensis subsp. novicida U112 4547977 YP_898687.1 CDS wzb NC_008601.1 1105057 1105542 R low molecular weight (LMW) phosphotyrosine protein phosphatase complement(1105057..1105542) Francisella tularensis subsp. novicida U112 4547978 YP_898688.1 CDS hflC NC_008601.1 1105543 1106469 R HflK-HflC membrane protein complex, HflC complement(1105543..1106469) Francisella tularensis subsp. novicida U112 4547979 YP_898689.1 CDS hflK NC_008601.1 1106471 1107538 R HflK-HflC membrane protein complex, HflK complement(1106471..1107538) Francisella tularensis subsp. novicida U112 4547980 YP_898690.1 CDS FTN_1049 NC_008601.1 1107723 1108901 D hypothetical protein 1107723..1108901 Francisella tularensis subsp. novicida U112 4547981 YP_898691.1 CDS hflX NC_008601.1 1108912 1110222 R protease, GTP-binding subunit complement(1108912..1110222) Francisella tularensis subsp. novicida U112 4547982 YP_898692.1 CDS hfq NC_008601.1 1110271 1110600 R host factor I for bacteriophage Q beta replication complement(1110271..1110600) Francisella tularensis subsp. novicida U112 4547983 YP_898693.1 CDS miaA NC_008601.1 1110711 1111637 R IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase complement(1110711..1111637) Francisella tularensis subsp. novicida U112 4547984 YP_898694.1 CDS FTN_1053 NC_008601.1 1111638 1113071 R hypothetical protein complement(1111638..1113071) Francisella tularensis subsp. novicida U112 4547985 YP_898695.1 CDS hupB NC_008601.1 1113184 1113456 R DNA-binding protein HU-beta complement(1113184..1113456) Francisella tularensis subsp. novicida U112 4547986 YP_898696.1 CDS lon NC_008601.1 1113543 1115867 R DNA-binding, ATP-dependent protease La complement(1113543..1115867) Francisella tularensis subsp. novicida U112 4547987 YP_898697.1 CDS clpX NC_008601.1 1115892 1117145 R binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX complement(1115892..1117145) Francisella tularensis subsp. novicida U112 4547988 YP_898698.1 CDS clpP NC_008601.1 1117169 1117774 R hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit complement(1117169..1117774) Francisella tularensis subsp. novicida U112 4547989 YP_898699.1 CDS tig NC_008601.1 1117800 1119116 R Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor complement(1117800..1119116) Francisella tularensis subsp. novicida U112 4547990 YP_898700.1 CDS FTN_1059 NC_008601.1 1119271 1119735 D hypothetical protein 1119271..1119735 Francisella tularensis subsp. novicida U112 4547991 YP_898701.1 CDS tdk NC_008601.1 1119778 1120371 R catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase complement(1119778..1120371) Francisella tularensis subsp. novicida U112 4547992 YP_898702.1 CDS FTN_1061 NC_008601.1 1120387 1121136 R acid phosphatase complement(1120387..1121136) Francisella tularensis subsp. novicida U112 4547993 YP_898703.1 CDS FTN_1062 NC_008601.1 1121316 1121990 R o-methyltransferase family protein complement(1121316..1121990) Francisella tularensis subsp. novicida U112 4547994 YP_898704.1 CDS FTN_1063 NC_008601.1 1122215 1123543 D catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 1122215..1123543 Francisella tularensis subsp. novicida U112 4547995 YP_898705.1 CDS FTN_1064 NC_008601.1 1123547 1124530 D PhoH family protein ATPase 1123547..1124530 Francisella tularensis subsp. novicida U112 4547996 YP_898706.1 CDS FTN_1065 NC_008601.1 1124523 1125011 D hypothetical protein 1124523..1125011 Francisella tularensis subsp. novicida U112 4547997 YP_898707.1 CDS FTN_1066 NC_008601.1 1125001 1125843 D HlyC/CorC family transporter-associated protein 1125001..1125843 Francisella tularensis subsp. novicida U112 4547998 YP_898708.1 CDS FTN_1067 NC_008601.1 1125843 1127333 D apolipoprotein N-acyltransferase 1125843..1127333 Francisella tularensis subsp. novicida U112 4547999 YP_898709.1 CDS FTN_1068 NC_008601.1 1127581 1128003 D hypothetical protein 1127581..1128003 Francisella tularensis subsp. novicida U112 4548000 YP_898710.1 CDS FTN_1069 NC_008601.1 1128155 1130653 R hypothetical protein complement(1128155..1130653) Francisella tularensis subsp. novicida U112 4547474 YP_898711.1 CDS FTN_1070 NC_008601.1 1130861 1132213 R hypothetical protein complement(1130861..1132213) Francisella tularensis subsp. novicida U112 4547475 YP_898712.1 CDS FTN_1071 NC_008601.1 1132421 1133899 R hypothetical protein complement(1132421..1133899) Francisella tularensis subsp. novicida U112 4547476 YP_898713.1 CDS FTN_1072 NC_008601.1 1134341 1135204 D beta-lactamase class A 1134341..1135204 Francisella tularensis subsp. novicida U112 4547477 YP_898714.1 CDS FTN_1073 NC_008601.1 1135195 1136259 R DNA/RNA endonuclease G complement(1135195..1136259) Francisella tularensis subsp. novicida U112 4547478 YP_898715.1 CDS FTN_1074 NC_008601.1 1136357 1138117 R X-prolyl aminopeptidase 2 complement(1136357..1138117) Francisella tularensis subsp. novicida U112 4547479 YP_898716.1 CDS FTN_1075 NC_008601.1 1138169 1138876 R hypothetical protein complement(1138169..1138876) Francisella tularensis subsp. novicida U112 4547480 YP_898717.1 CDS ispG NC_008601.1 1138891 1140108 R catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase complement(1138891..1140108) Francisella tularensis subsp. novicida U112 4547481 YP_898718.1 CDS FTN_1077 NC_008601.1 1140193 1140939 D hypothetical protein 1140193..1140939 Francisella tularensis subsp. novicida U112 4547482 YP_898719.1 CDS FTN_1079 NC_008601.1 1141285 1142637 R major facilitator superfamily sugar transporter complement(1141285..1142637) Francisella tularensis subsp. novicida U112 4547484 YP_898720.1 CDS FTN_1080 NC_008601.1 1142671 1143699 R phosphosugar binding protein complement(1142671..1143699) Francisella tularensis subsp. novicida U112 4547485 YP_898721.1 CDS FTN_1081 NC_008601.1 1143901 1145175 D dicarboxylate/amino acid:cation (Na+ or H+) symporter 1143901..1145175 Francisella tularensis subsp. novicida U112 4547486 YP_898722.1 CDS FTN_1082 NC_008601.1 1145207 1146601 R hypothetical protein complement(1145207..1146601) Francisella tularensis subsp. novicida U112 4547487 YP_898723.1 CDS FTN_1083 NC_008601.1 1146713 1147330 D hypothetical protein 1146713..1147330 Francisella tularensis subsp. novicida U112 4547488 YP_898724.1 CDS rubA NC_008601.1 1147417 1147587 D rubredoxin 1147417..1147587 Francisella tularensis subsp. novicida U112 4547489 YP_898725.1 CDS FTN_1085 NC_008601.1 1147596 1148468 D hypothetical protein 1147596..1148468 Francisella tularensis subsp. novicida U112 4547490 YP_898726.1 CDS FTN_1086 NC_008601.1 1148532 1149137 D hypothetical protein 1148532..1149137 Francisella tularensis subsp. novicida U112 4547491 YP_898727.1 CDS cynT NC_008601.1 1149424 1150110 R carbonic anhydrase complement(1149424..1150110) Francisella tularensis subsp. novicida U112 4547492 YP_898728.1 CDS ansA NC_008601.1 1150181 1151218 R L-asparaginase complement(1150181..1151218) Francisella tularensis subsp. novicida U112 4548648 YP_898729.1 CDS rnhA NC_008601.1 1151220 1151678 R ribonuclease H complement(1151220..1151678) Francisella tularensis subsp. novicida U112 4548649 YP_898730.1 CDS FTN_1090 NC_008601.1 1151653 1152243 R hypothetical protein complement(1151653..1152243) Francisella tularensis subsp. novicida U112 4548650 YP_898731.1 CDS aroA NC_008601.1 1152246 1153523 R 3-phosphoshikimate 1-carboxyvinyltransferase complement(1152246..1153523) Francisella tularensis subsp. novicida U112 4548651 YP_898732.1 CDS rpoH NC_008601.1 1153614 1154492 R binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 complement(1153614..1154492) Francisella tularensis subsp. novicida U112 4548652 YP_898733.1 CDS FTN_1093 NC_008601.1 1154516 1155004 R hypothetical protein complement(1154516..1155004) Francisella tularensis subsp. novicida U112 4548653 YP_898734.1 CDS secF NC_008601.1 1155078 1156022 R forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF complement(1155078..1156022) Francisella tularensis subsp. novicida U112 4548654 YP_898735.1 CDS secD NC_008601.1 1156041 1157978 R part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD complement(1156041..1157978) Francisella tularensis subsp. novicida U112 4548655 YP_898736.1 CDS yajC NC_008601.1 1158035 1158391 R preprotein translocase family protein complement(1158035..1158391) Francisella tularensis subsp. novicida U112 4548656 YP_898737.1 CDS FTN_1097 NC_008601.1 1158943 1159515 R isochorismatase hydrolase family protein complement(1158943..1159515) Francisella tularensis subsp. novicida U112 4548657 YP_898738.1 CDS FTN_1098 NC_008601.1 1159527 1160402 R hypothetical protein complement(1159527..1160402) Francisella tularensis subsp. novicida U112 4548658 YP_898739.1 CDS FTN_1099 NC_008601.1 1160507 1161382 D LysR family transcriptional regulator 1160507..1161382 Francisella tularensis subsp. novicida U112 4548659 YP_898740.1 CDS tgt NC_008601.1 1161389 1162492 R Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase complement(1161389..1162492) Francisella tularensis subsp. novicida U112 4548660 YP_898741.1 CDS FTN_1101 NC_008601.1 1162957 1163790 R hypothetical protein complement(1162957..1163790) Francisella tularensis subsp. novicida U112 4548661 YP_898742.1 CDS FTN_1102 NC_008601.1 1164373 1164603 D hypothetical protein 1164373..1164603 Francisella tularensis subsp. novicida U112 4548662 YP_898743.1 CDS FTN_1103 NC_008601.1 1164644 1165492 R hypothetical protein complement(1164644..1165492) Francisella tularensis subsp. novicida U112 4548663 YP_898744.1 CDS FTN_1104 NC_008601.1 1165519 1166067 R hypothetical protein complement(1165519..1166067) Francisella tularensis subsp. novicida U112 4548664 YP_898745.1 CDS FTN_1105 NC_008601.1 1166699 1167313 D hypothetical protein 1166699..1167313 Francisella tularensis subsp. novicida U112 4548665 YP_898746.1 CDS metN NC_008601.1 1167276 1168352 D methionine uptake transporter (MUT) family protein 1167276..1168352 Francisella tularensis subsp. novicida U112 4548666 YP_898747.1 CDS metlQ NC_008601.1 1168330 1169802 D methionine uptake transporter (MUT) family protein, membrane and periplasmic protein 1168330..1169802 Francisella tularensis subsp. novicida U112 4548667 YP_898748.1 CDS FTN_1108 NC_008601.1 1169873 1171084 D hydroxy/aromatic amino acid permease (HAAAP) family protein 1169873..1171084 Francisella tularensis subsp. novicida U112 4547889 YP_898749.1 CDS FTN_1109 NC_008601.1 1171158 1171907 D rhodanese-like family protein 1171158..1171907 Francisella tularensis subsp. novicida U112 4547890 YP_898750.1 CDS ispF NC_008601.1 1171920 1172399 D catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 1171920..1172399 Francisella tularensis subsp. novicida U112 4547891 YP_898751.1 CDS FTN_1111 NC_008601.1 1172404 1174089 R Mur ligase family protein complement(1172404..1174089) Francisella tularensis subsp. novicida U112 4547892 YP_898752.1 CDS cphA NC_008601.1 1174115 1176937 R catalyze the formation of cyanophycin which may act to store excess nitrogen; cyanophycin synthetase complement(1174115..1176937) Francisella tularensis subsp. novicida U112 4547893 YP_898753.1 CDS FTN_1113 NC_008601.1 1177061 1177804 D hypothetical protein 1177061..1177804 Francisella tularensis subsp. novicida U112 4547894 YP_898754.1 CDS glpQ NC_008601.1 1177793 1178545 R glycerophosphoryl diester phosphodiesterase complement(1177793..1178545) Francisella tularensis subsp. novicida U112 4547895 YP_898755.1 CDS pilB NC_008601.1 1178703 1180481 D Type IV pili ATPase 1178703..1180481 Francisella tularensis subsp. novicida U112 4547896 YP_898756.1 CDS pilC NC_008601.1 1180496 1181725 D Type IV pili polytopic inner membrane protein 1180496..1181725 Francisella tularensis subsp. novicida U112 4547897 YP_898757.1 CDS FTN_1117 NC_008601.1 1181799 1182965 R ATP-binding protein complement(1181799..1182965) Francisella tularensis subsp. novicida U112 4547898 YP_898758.1 CDS FTN_1118 NC_008601.1 1182983 1183318 R hypothetical protein complement(1182983..1183318) Francisella tularensis subsp. novicida U112 4547899 YP_898759.1 CDS FTN_1119 NC_008601.1 1183335 1183586 R hypothetical protein complement(1183335..1183586) Francisella tularensis subsp. novicida U112 4547900 YP_898760.1 CDS hemH NC_008601.1 1183729 1184730 D protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 1183729..1184730 Francisella tularensis subsp. novicida U112 4547901 YP_898761.1 CDS phrB NC_008601.1 1184715 1186109 D deoxyribodipyrimidine photolyase 1184715..1186109 Francisella tularensis subsp. novicida U112 4547902 YP_898762.1 CDS FTN_1122 NC_008601.1 1186844 1187233 D hypothetical protein 1186844..1187233 Francisella tularensis subsp. novicida U112 4547903 YP_898763.1 CDS FTN_1123 NC_008601.1 1187288 1187593 D hypothetical protein 1187288..1187593 Francisella tularensis subsp. novicida U112 4547904 YP_898764.1 CDS FTN_1124 NC_008601.1 1187659 1187904 D hypothetical protein 1187659..1187904 Francisella tularensis subsp. novicida U112 4547905 YP_898765.1 CDS FTN_1125 NC_008601.1 1188089 1188952 D short chain dehydrogenase 1188089..1188952 Francisella tularensis subsp. novicida U112 4547906 YP_898766.1 CDS chaB NC_008601.1 1188964 1189194 D cation transport regulator 1188964..1189194 Francisella tularensis subsp. novicida U112 4547907 YP_898767.1 CDS galM NC_008601.1 1189304 1190299 R aldose 1-epimerase complement(1189304..1190299) Francisella tularensis subsp. novicida U112 4548705 YP_898768.1 CDS dfp NC_008601.1 1190296 1191471 R P-pantothenate cysteine ligase/P-pantothenoylcysteine decarboxylase complement(1190296..1191471) Francisella tularensis subsp. novicida U112 4548706 YP_898769.1 CDS FTN_1129 NC_008601.1 1191484 1192668 R major facilitator transporter complement(1191484..1192668) Francisella tularensis subsp. novicida U112 4548707 YP_898770.1 CDS FTN_1130 NC_008601.1 1192744 1194252 R amino acid transporter complement(1192744..1194252) Francisella tularensis subsp. novicida U112 4548708 YP_898771.1 CDS putA NC_008601.1 1194413 1198477 R proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the protein from Pseudomonas does not have this domain; bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase complement(1194413..1198477) Francisella tularensis subsp. novicida U112 4548709 YP_898772.1 CDS FTN_1132 NC_008601.1 1198494 1198781 R hypothetical protein complement(1198494..1198781) Francisella tularensis subsp. novicida U112 4548710 YP_898773.1 CDS FTN_1133 NC_008601.1 1198995 1199378 D hypothetical protein 1198995..1199378 Francisella tularensis subsp. novicida U112 4548711 YP_898774.1 CDS FTN_1134 NC_008601.1 1199445 1199690 R hypothetical protein complement(1199445..1199690) Francisella tularensis subsp. novicida U112 4548712 YP_898775.1 CDS aroB NC_008601.1 1199726 1200805 R catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase complement(1199726..1200805) Francisella tularensis subsp. novicida U112 4548713 YP_898776.1 CDS aroK NC_008601.1 1200802 1201332 R type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I complement(1200802..1201332) Francisella tularensis subsp. novicida U112 4548714 YP_898777.1 CDS pilQ NC_008601.1 1201458 1203242 R Type IV pili secretin component complement(1201458..1203242) Francisella tularensis subsp. novicida U112 4548715 YP_898778.1 CDS pilP NC_008601.1 1203255 1203845 R Type IV pili periplasmic component complement(1203255..1203845) Francisella tularensis subsp. novicida U112 4548716 YP_898779.1 CDS pilO NC_008601.1 1203851 1204447 R Type IV pili glycosylation protein complement(1203851..1204447) Francisella tularensis subsp. novicida U112 4548717 YP_898780.1 CDS pilN NC_008601.1 1204441 1205004 R Type IV pili associated protein complement(1204441..1205004) Francisella tularensis subsp. novicida U112 4548718 YP_898781.1 CDS pilM NC_008601.1 1205006 1206010 R hypothetical protein complement(1205006..1206010) Francisella tularensis subsp. novicida U112 4548719 YP_898782.1 CDS adk NC_008601.1 1206137 1206793 D essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 1206137..1206793 Francisella tularensis subsp. novicida U112 4548720 YP_898783.1 CDS FTN_1143 NC_008601.1 1207352 1210072 R 4Fe-4S ferredoxin complement(1207352..1210072) Francisella tularensis subsp. novicida U112 4548721 YP_898784.1 CDS FTN_1144 NC_008601.1 1210133 1210549 R hypothetical protein complement(1210133..1210549) Francisella tularensis subsp. novicida U112 4548722 YP_898785.1 CDS era NC_008601.1 1210564 1211457 R Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era complement(1210564..1211457) Francisella tularensis subsp. novicida U112 4548723 YP_898786.1 CDS FTN_1146 NC_008601.1 1211571 1212764 R aspartate aminotransferase complement(1211571..1212764) Francisella tularensis subsp. novicida U112 4548724 YP_898787.1 CDS FTN_1147 NC_008601.1 1212774 1213580 R glutamine amidotransferases class-II family protein complement(1212774..1213580) Francisella tularensis subsp. novicida U112 4548133 YP_898788.1 CDS FTN_1148 NC_008601.1 1213584 1214222 R glycoprotease family protein complement(1213584..1214222) Francisella tularensis subsp. novicida U112 4548134 YP_898789.1 CDS nagA NC_008601.1 1214226 1215359 R N-acetylglucosamine-6-phosphate deacetylase complement(1214226..1215359) Francisella tularensis subsp. novicida U112 4548135 YP_898790.1 CDS FTN_1150 NC_008601.1 1215422 1216294 D GTP-binding protein 1215422..1216294 Francisella tularensis subsp. novicida U112 4548136 YP_898791.1 CDS FTN_1151 NC_008601.1 1216361 1218109 D hypothetical protein 1216361..1218109 Francisella tularensis subsp. novicida U112 4548137 YP_898792.1 CDS FTN_1152 NC_008601.1 1218099 1219547 R type I restriction-modification system subunit M (methyltransferase) complement(1218099..1219547) Francisella tularensis subsp. novicida U112 4548138 YP_898793.1 CDS FTN_1153 NC_008601.1 1219528 1220226 R hypothetical protein complement(1219528..1220226) Francisella tularensis subsp. novicida U112 4548139 YP_898794.1 CDS FTN_1154 NC_008601.1 1220793 1222016 R type I restriction-modification system subunit S complement(1220793..1222016) Francisella tularensis subsp. novicida U112 4548140 YP_898795.1 CDS FTN_1155 NC_008601.1 1222621 1224969 R type I restriction-modification system subunit R (restriction) complement(1222621..1224969) Francisella tularensis subsp. novicida U112 4548141 YP_898796.1 CDS FTN_1156 NC_008601.1 1225102 1226655 R hypothetical protein complement(1225102..1226655) Francisella tularensis subsp. novicida U112 4548142 YP_898797.1 CDS FTN_1157 NC_008601.1 1227077 1228894 D GTP binding translational elongation factor Tu and G family protein 1227077..1228894 Francisella tularensis subsp. novicida U112 4548143 YP_898798.1 CDS FTN_1158 NC_008601.1 1229066 1229821 D methyltransferase 1229066..1229821 Francisella tularensis subsp. novicida U112 4548144 YP_898799.1 CDS ggt NC_008601.1 1229837 1231642 R gamma-glutamyltranspeptidase complement(1229837..1231642) Francisella tularensis subsp. novicida U112 4548145 YP_898800.1 CDS FTN_1160 NC_008601.1 1231698 1232618 R VacJ like lipoprotein complement(1231698..1232618) Francisella tularensis subsp. novicida U112 4548146 YP_898801.1 CDS FTN_1161 NC_008601.1 1232695 1233897 R hypothetical protein complement(1232695..1233897) Francisella tularensis subsp. novicida U112 4548147 YP_898802.1 CDS FTN_1162 NC_008601.1 1233939 1234244 R hypothetical protein complement(1233939..1234244) Francisella tularensis subsp. novicida U112 4548148 YP_898803.1 CDS FTN_1163 NC_008601.1 1234244 1234675 R hypothetical protein complement(1234244..1234675) Francisella tularensis subsp. novicida U112 4548149 YP_898804.1 CDS smpB NC_008601.1 1234750 1235223 D binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 1234750..1235223 Francisella tularensis subsp. novicida U112 4548150 YP_898805.1 CDS FTN_1165 NC_008601.1 1235224 1235985 D TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 1235224..1235985 Francisella tularensis subsp. novicida U112 4548151 YP_898806.1 CDS FTN_1166 NC_008601.1 1235986 1237257 R metabolite:H+ symporter (MHS) family protein complement(1235986..1237257) Francisella tularensis subsp. novicida U112 4548725 YP_898807.1 CDS FTN_1167 NC_008601.1 1237355 1237555 R hypothetical protein complement(1237355..1237555) Francisella tularensis subsp. novicida U112 4548726 YP_898808.1 CDS xseA NC_008601.1 1237539 1238924 R bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit complement(1237539..1238924) Francisella tularensis subsp. novicida U112 4548727 YP_898809.1 CDS FTN_1169 NC_008601.1 1239077 1240237 D M20 family peptidase 1239077..1240237 Francisella tularensis subsp. novicida U112 4548728 YP_898810.1 CDS FTN_1170 NC_008601.1 1240286 1242037 R hypothetical protein complement(1240286..1242037) Francisella tularensis subsp. novicida U112 4548729 YP_898811.1 CDS FTN_1171 NC_008601.1 1242054 1243040 R hypothetical protein complement(1242054..1243040) Francisella tularensis subsp. novicida U112 4548730 YP_898812.1 CDS FTN_1172 NC_008601.1 1243040 1244494 R hypothetical protein complement(1243040..1244494) Francisella tularensis subsp. novicida U112 4548731 YP_898813.1 CDS FTN_1173 NC_008601.1 1244655 1245932 R major facilitator transporter complement(1244655..1245932) Francisella tularensis subsp. novicida U112 4548732 YP_898814.1 CDS murI NC_008601.1 1246023 1246820 R glutamate racemase complement(1246023..1246820) Francisella tularensis subsp. novicida U112 4548733 YP_898815.1 CDS FTN_1175 NC_008601.1 1246820 1247617 R hypothetical protein complement(1246820..1247617) Francisella tularensis subsp. novicida U112 4548734 YP_898816.1 CDS uvrB NC_008601.1 1247654 1249660 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B complement(1247654..1249660) Francisella tularensis subsp. novicida U112 4548735 YP_898817.1 CDS sbcB NC_008601.1 1249662 1251110 R exodeoxyribonuclease I complement(1249662..1251110) Francisella tularensis subsp. novicida U112 4548736 YP_898818.1 CDS FTN_1178 NC_008601.1 1251244 1251966 R short-chain dehydrogenase complement(1251244..1251966) Francisella tularensis subsp. novicida U112 4548737 YP_898819.1 CDS FTN_1179 NC_008601.1 1252082 1252981 D LysR family transcriptional regulator 1252082..1252981 Francisella tularensis subsp. novicida U112 4548738 YP_898820.1 CDS FTN_1180 NC_008601.1 1252992 1253897 R hypothetical protein complement(1252992..1253897) Francisella tularensis subsp. novicida U112 4548739 YP_898821.1 CDS FTN_1181 NC_008601.1 1253884 1254966 R hypothetical protein complement(1253884..1254966) Francisella tularensis subsp. novicida U112 4548740 YP_898822.1 CDS gidA NC_008601.1 1255109 1256992 D GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 1255109..1256992 Francisella tularensis subsp. novicida U112 4548741 YP_898823.1 CDS FTN_1183 NC_008601.1 1257004 1257396 D hypothetical protein 1257004..1257396 Francisella tularensis subsp. novicida U112 4548742 YP_898824.1 CDS FTN_1184 NC_008601.1 1257410 1258780 D hypothetical protein 1257410..1258780 Francisella tularensis subsp. novicida U112 4548743 YP_898825.1 CDS rpiA NC_008601.1 1258782 1259456 D Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 1258782..1259456 Francisella tularensis subsp. novicida U112 4548744 YP_898826.1 CDS pepO NC_008601.1 1259504 1261567 R M13 family metallopeptidase complement(1259504..1261567) Francisella tularensis subsp. novicida U112 4547607 YP_898827.1 CDS FTN_1187 NC_008601.1 1261656 1262360 R hypothetical protein complement(1261656..1262360) Francisella tularensis subsp. novicida U112 4547608 YP_898828.1 CDS rplT NC_008601.1 1262402 1262758 R binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 complement(1262402..1262758) Francisella tularensis subsp. novicida U112 4547609 YP_898829.1 CDS rpmI NC_008601.1 1262794 1262991 R 50S ribosomal protein L35 complement(1262794..1262991) Francisella tularensis subsp. novicida U112 4547610 YP_898830.1 CDS infC NC_008601.1 1263034 1263570 R translation initiation factor IF-3 complement(1263034..1263570) Francisella tularensis subsp. novicida U112 4547611 YP_898831.1 CDS thrS NC_008601.1 1263577 1265481 R catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase complement(1263577..1265481) Francisella tularensis subsp. novicida U112 4547612 YP_898832.1 CDS FTN_1192 NC_008601.1 1265920 1267710 D chitin-binding protein 1265920..1267710 Francisella tularensis subsp. novicida U112 4547613 YP_898833.1 CDS FTN_1193 NC_008601.1 1267795 1268091 R hypothetical protein complement(1267795..1268091) Francisella tularensis subsp. novicida U112 4547614 YP_898834.1 CDS gcvH1 NC_008601.1 1268081 1268461 R glycine cleavage system protein H complement(1268081..1268461) Francisella tularensis subsp. novicida U112 4547615 YP_898835.1 CDS murG NC_008601.1 1268565 1269680 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 1268565..1269680 Francisella tularensis subsp. novicida U112 4547616 YP_898836.1 CDS FTN_1196 NC_008601.1 1269690 1270028 D hypothetical protein 1269690..1270028 Francisella tularensis subsp. novicida U112 4547617 YP_898837.1 CDS recR NC_008601.1 1270028 1270630 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 1270028..1270630 Francisella tularensis subsp. novicida U112 4547618 YP_898838.1 CDS spoT NC_008601.1 1270638 1272752 R GDP diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase complement(1270638..1272752) Francisella tularensis subsp. novicida U112 4547619 YP_898839.1 CDS FTN_1199 NC_008601.1 1272821 1274032 R hypothetical protein complement(1272821..1274032) Francisella tularensis subsp. novicida U112 4547620 YP_898840.1 CDS capC NC_008601.1 1274034 1274498 R capsule biosynthesis protein CapC complement(1274034..1274498) Francisella tularensis subsp. novicida U112 4547621 YP_898841.1 CDS capB NC_008601.1 1274523 1275740 R capsule biosynthesis protein CapB complement(1274523..1275740) Francisella tularensis subsp. novicida U112 4547622 YP_898842.1 CDS FTN_1202 NC_008601.1 1275816 1277072 R metabolite:H+ symporter (MHS) family protein complement(1275816..1277072) Francisella tularensis subsp. novicida U112 4547623 YP_898843.1 CDS ans NC_008601.1 1277743 1278606 R asparaginase complement(1277743..1278606) Francisella tularensis subsp. novicida U112 4547386 YP_898844.1 CDS cphB NC_008601.1 1278821 1279639 R cyanophycinase complement(1278821..1279639) Francisella tularensis subsp. novicida U112 4547387 YP_898845.1 CDS FTN_1210 NC_008601.1 1279841 1280947 D ribokinase 1279841..1280947 Francisella tularensis subsp. novicida U112 4547388 YP_898846.1 CDS FTN_1211 NC_008601.1 1281238 1281900 R haloacid dehalogenase-like hydrolase complement(1281238..1281900) Francisella tularensis subsp. novicida U112 4547389 YP_898847.1 CDS FTN_1212 NC_008601.1 1281919 1282932 R glycosyl transferases group 1 family protein complement(1281919..1282932) Francisella tularensis subsp. novicida U112 4547390 YP_898848.1 CDS FTN_1213 NC_008601.1 1282935 1283942 R glycosyl transferase family protein complement(1282935..1283942) Francisella tularensis subsp. novicida U112 4547391 YP_898849.1 CDS FTN_1214 NC_008601.1 1283959 1284918 R glycosyl transferase family protein complement(1283959..1284918) Francisella tularensis subsp. novicida U112 4547392 YP_898850.1 CDS kpsC NC_008601.1 1284952 1286112 R capsule polysaccharide export protein KpsC complement(1284952..1286112) Francisella tularensis subsp. novicida U112 4547393 YP_898851.1 CDS FTN_1216 NC_008601.1 1286105 1286848 R hypothetical protein complement(1286105..1286848) Francisella tularensis subsp. novicida U112 4547394 YP_898852.1 CDS FTN_1217 NC_008601.1 1286885 1288573 R ABC transporter ATP-binding protein complement(1286885..1288573) Francisella tularensis subsp. novicida U112 4547395 YP_898853.1 CDS FTN_1218 NC_008601.1 1288570 1289799 R group 1 glycosyl transferase complement(1288570..1289799) Francisella tularensis subsp. novicida U112 4547396 YP_898854.1 CDS galE NC_008601.1 1289803 1290822 R UDP-glucose 4-epimerase complement(1289803..1290822) Francisella tularensis subsp. novicida U112 4548970 YP_898855.1 CDS FTN_1220 NC_008601.1 1290815 1292209 R lipopolysaccharide synthesis sugar transferase complement(1290815..1292209) Francisella tularensis subsp. novicida U112 4548971 YP_898856.1 CDS rpe NC_008601.1 1292190 1292858 R D-ribulose-phosphate 3-epimerase complement(1292190..1292858) Francisella tularensis subsp. novicida U112 4548972 YP_898857.1 CDS kpsF NC_008601.1 1292995 1293966 D phosphosugar isomerase 1292995..1293966 Francisella tularensis subsp. novicida U112 4548973 YP_898858.1 CDS FTN_1223 NC_008601.1 1293970 1294560 R hypothetical protein complement(1293970..1294560) Francisella tularensis subsp. novicida U112 4548974 YP_898859.1 CDS FTN_1224 NC_008601.1 1294571 1295269 R hypothetical protein complement(1294571..1295269) Francisella tularensis subsp. novicida U112 4548975 YP_898860.1 CDS FTN_1225 NC_008601.1 1295266 1296078 R hypothetical protein complement(1295266..1296078) Francisella tularensis subsp. novicida U112 4548976 YP_898861.1 CDS FTN_1226 NC_008601.1 1296075 1296404 R hypothetical protein complement(1296075..1296404) Francisella tularensis subsp. novicida U112 4548977 YP_898862.1 CDS FTN_1227 NC_008601.1 1296416 1297378 R metallo-beta-lactamase superfamily protein complement(1296416..1297378) Francisella tularensis subsp. novicida U112 4548978 YP_898863.1 CDS fabl NC_008601.1 1297525 1298307 R enoyl-ACP reductase I complement(1297525..1298307) Francisella tularensis subsp. novicida U112 4548979 YP_898864.1 CDS FTN_1229 NC_008601.1 1298595 1299308 D hypothetical protein 1298595..1299308 Francisella tularensis subsp. novicida U112 4548980 YP_898865.1 CDS FTN_1230 NC_008601.1 1299556 1300131 R hypothetical protein complement(1299556..1300131) Francisella tularensis subsp. novicida U112 4548981 YP_898866.1 CDS gloA NC_008601.1 1300131 1300514 R lactoylglutathione lyase complement(1300131..1300514) Francisella tularensis subsp. novicida U112 4548982 YP_898867.1 CDS FTN_1232 NC_008601.1 1300558 1301343 D hypothetical protein 1300558..1301343 Francisella tularensis subsp. novicida U112 4548983 YP_898868.1 CDS FTN_1233 NC_008601.1 1301595 1302386 R haloacid dehalogenase-like hydrolase complement(1301595..1302386) Francisella tularensis subsp. novicida U112 4548984 YP_898869.1 CDS queA NC_008601.1 1302509 1303525 R Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase complement(1302509..1303525) Francisella tularensis subsp. novicida U112 4548985 YP_898870.1 CDS FTN_1235 NC_008601.1 1303551 1304012 R hypothetical protein complement(1303551..1304012) Francisella tularensis subsp. novicida U112 4548986 YP_898871.1 CDS ubiF NC_008601.1 1304034 1305269 R 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase complement(1304034..1305269) Francisella tularensis subsp. novicida U112 4548987 YP_898872.1 CDS ubiH NC_008601.1 1305259 1306470 R 2-octaprenyl-6-methoxyphenyl hydroxylase complement(1305259..1306470) Francisella tularensis subsp. novicida U112 4548988 YP_898873.1 CDS FTN_1238 NC_008601.1 1306479 1307129 R hypothetical protein complement(1306479..1307129) Francisella tularensis subsp. novicida U112 4548989 YP_898874.1 CDS FTN_1239 NC_008601.1 1307455 1308003 D 5-formyltetrahydrofolate cyclo-ligase 1307455..1308003 Francisella tularensis subsp. novicida U112 4548038 YP_898875.1 CDS FTN_1240 NC_008601.1 1308006 1308272 D hypothetical protein 1308006..1308272 Francisella tularensis subsp. novicida U112 4548039 YP_898876.1 CDS FTN_1241 NC_008601.1 1308279 1308905 D DedA family protein 1308279..1308905 Francisella tularensis subsp. novicida U112 4548040 YP_898877.1 CDS FTN_1242 NC_008601.1 1308961 1309608 D DedA family protein 1308961..1309608 Francisella tularensis subsp. novicida U112 4548041 YP_898878.1 CDS recO NC_008601.1 1309684 1310382 R RecFOR complex, RecO component complement(1309684..1310382) Francisella tularensis subsp. novicida U112 4548042 YP_898879.1 CDS FTN_1244 NC_008601.1 1310366 1310695 R hypothetical protein complement(1310366..1310695) Francisella tularensis subsp. novicida U112 4548043 YP_898880.1 CDS iscS NC_008601.1 1310688 1311863 R cysteine desulfarase complement(1310688..1311863) Francisella tularensis subsp. novicida U112 4548044 YP_898881.1 CDS rne NC_008601.1 1312113 1314770 D ribonuclease E 1312113..1314770 Francisella tularensis subsp. novicida U112 4548045 YP_898882.1 CDS lgt NC_008601.1 1314785 1315591 D transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 1314785..1315591 Francisella tularensis subsp. novicida U112 4548046 YP_898883.1 CDS thyA NC_008601.1 1315576 1316400 D ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 1315576..1316400 Francisella tularensis subsp. novicida U112 4548047 YP_898884.1 CDS serA NC_008601.1 1316412 1317647 D catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 1316412..1317647 Francisella tularensis subsp. novicida U112 4548048 YP_898885.1 CDS FTN_1250 NC_008601.1 1317648 1318844 D ATPase 1317648..1318844 Francisella tularensis subsp. novicida U112 4548049 YP_898886.1 CDS FTN_1251 NC_008601.1 1318852 1320288 R proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter complement(1318852..1320288) Francisella tularensis subsp. novicida U112 4548050 YP_898887.1 CDS FTN_1252 NC_008601.1 1320488 1321633 D choloylglycine hydrolase family protein 1320488..1321633 Francisella tularensis subsp. novicida U112 4548051 YP_898888.1 CDS lpcC NC_008601.1 1321634 1322698 R group 1 glycosyl transferase complement(1321634..1322698) Francisella tularensis subsp. novicida U112 4548052 YP_898889.1 CDS FTN_1254 NC_008601.1 1322868 1323956 D hypothetical protein 1322868..1323956 Francisella tularensis subsp. novicida U112 4548053 YP_898890.1 CDS FTN_1255 NC_008601.1 1323964 1324854 D glycosyl transferase family protein 1323964..1324854 Francisella tularensis subsp. novicida U112 4548054 YP_898891.1 CDS FTN_1256 NC_008601.1 1324880 1326250 R hypothetical protein complement(1324880..1326250) Francisella tularensis subsp. novicida U112 4548055 YP_898892.1 CDS FTN_1257 NC_008601.1 1326405 1327676 D hypothetical protein 1326405..1327676 Francisella tularensis subsp. novicida U112 4548056 YP_898893.1 CDS FTN_1258 NC_008601.1 1327691 1328239 R hypothetical protein complement(1327691..1328239) Francisella tularensis subsp. novicida U112 4547701 YP_898894.1 CDS glyA NC_008601.1 1328343 1329596 D catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 1328343..1329596 Francisella tularensis subsp. novicida U112 4547702 YP_898895.1 CDS FTN_1260 NC_008601.1 1329874 1331328 D hypothetical protein 1329874..1331328 Francisella tularensis subsp. novicida U112 4547703 YP_898896.1 CDS FTN_1261 NC_008601.1 1331640 1333127 D hypothetical protein 1331640..1333127 Francisella tularensis subsp. novicida U112 4547704 YP_898897.1 CDS mreA NC_008601.1 1333171 1334967 R FAD binding family protein complement(1333171..1334967) Francisella tularensis subsp. novicida U112 4547705 YP_898898.1 CDS comL NC_008601.1 1335075 1335899 R competence lipoprotein ComL complement(1335075..1335899) Francisella tularensis subsp. novicida U112 4547706 YP_898899.1 CDS rluD NC_008601.1 1335988 1336986 D ribosomal large subunit pseudouridine synthase D 1335988..1336986 Francisella tularensis subsp. novicida U112 4547707 YP_898900.1 CDS FTN_1265 NC_008601.1 1336964 1337776 D hypothetical protein 1336964..1337776 Francisella tularensis subsp. novicida U112 4547708 YP_898901.1 CDS FTN_1266 NC_008601.1 1337851 1338951 D ABC transporter membrane protein 1337851..1338951 Francisella tularensis subsp. novicida U112 4547709 YP_898902.1 CDS FTN_1267 NC_008601.1 1338966 1339727 D ABC transporter ATP-binding protein 1338966..1339727 Francisella tularensis subsp. novicida U112 4547710 YP_898903.1 CDS FTN_1268 NC_008601.1 1339737 1340462 D hypothetical protein 1339737..1340462 Francisella tularensis subsp. novicida U112 4547711 YP_898904.1 CDS FTN_1269 NC_008601.1 1340467 1341165 D hypothetical protein 1340467..1341165 Francisella tularensis subsp. novicida U112 4547712 YP_898905.1 CDS FTN_1270 NC_008601.1 1341155 1341841 R hypothetical protein complement(1341155..1341841) Francisella tularensis subsp. novicida U112 4547713 YP_898906.1 CDS FTN_1271 NC_008601.1 1341912 1342640 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 1341912..1342640 Francisella tularensis subsp. novicida U112 4547714 YP_898907.1 CDS FTN_1272 NC_008601.1 1342876 1344360 D proton-dependent oligopeptide transporter (POT) family protein, di- or tripeptide:H+ symporter 1342876..1344360 Francisella tularensis subsp. novicida U112 4547715 YP_898908.1 CDS FTN_1273 NC_008601.1 1344468 1346159 D long chain fatty acid CoA ligase 1344468..1346159 Francisella tularensis subsp. novicida U112 4547716 YP_898909.1 CDS FTN_1274 NC_008601.1 1346147 1346974 R AraC family transcriptional regulator complement(1346147..1346974) Francisella tularensis subsp. novicida U112 4547717 YP_898910.1 CDS FTN_1275 NC_008601.1 1347139 1348668 D drug:H+ antiporter-1 (DHA2) family protein 1347139..1348668 Francisella tularensis subsp. novicida U112 4547718 YP_898911.1 CDS FTN_1276 NC_008601.1 1348690 1349715 D membrane fusion protein 1348690..1349715 Francisella tularensis subsp. novicida U112 4547719 YP_898912.1 CDS FTN_1277 NC_008601.1 1349725 1351197 D outer membrane efflux protein 1349725..1351197 Francisella tularensis subsp. novicida U112 4547720 YP_898913.1 CDS nadE NC_008601.1 1351324 1352073 D NAD synthase 1351324..1352073 Francisella tularensis subsp. novicida U112 4547625 YP_898914.1 CDS FTN_1279 NC_008601.1 1352177 1352599 D hypothetical protein 1352177..1352599 Francisella tularensis subsp. novicida U112 4547626 YP_898915.1 CDS FTN_1280 NC_008601.1 1352699 1353265 R tryptophan repressor binding protein-like flavidoxin complement(1352699..1353265) Francisella tularensis subsp. novicida U112 4547627 YP_898916.1 CDS FTN_1281 NC_008601.1 1353280 1353978 R pirin family protein complement(1353280..1353978) Francisella tularensis subsp. novicida U112 4547628 YP_898917.1 CDS FTN_1282 NC_008601.1 1354079 1354975 D LysR family transcriptional regulator 1354079..1354975 Francisella tularensis subsp. novicida U112 4547629 YP_898918.1 CDS dnaJ NC_008601.1 1354989 1356176 R contains C-terminal Zn finger domain; chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ complement(1354989..1356176) Francisella tularensis subsp. novicida U112 4547630 YP_898919.1 CDS dnaK NC_008601.1 1356202 1358130 R heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK complement(1356202..1358130) Francisella tularensis subsp. novicida U112 4547631 YP_898920.1 CDS grpE NC_008601.1 1358231 1358818 R with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE complement(1358231..1358818) Francisella tularensis subsp. novicida U112 4547632 YP_898921.1 CDS mltA NC_008601.1 1358907 1360073 D membrane-bound lytic murein transglycosylase 1358907..1360073 Francisella tularensis subsp. novicida U112 4547633 YP_898922.1 CDS hemG NC_008601.1 1360066 1361250 D hypothetical protein 1360066..1361250 Francisella tularensis subsp. novicida U112 4547634 YP_898923.1 CDS rplM NC_008601.1 1361389 1361817 D in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 1361389..1361817 Francisella tularensis subsp. novicida U112 4547635 YP_898924.1 CDS rpsI NC_008601.1 1361833 1362222 D forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 1361833..1362222 Francisella tularensis subsp. novicida U112 4547636 YP_898925.1 CDS mglA NC_008601.1 1362282 1362899 D macrophage growth locus, protein A 1362282..1362899 Francisella tularensis subsp. novicida U112 4547637 YP_898926.1 CDS mglB NC_008601.1 1362901 1363308 D ClpXP protease specificity-enhancing factor 1362901..1363308 Francisella tularensis subsp. novicida U112 4547638 YP_898927.1 CDS FTN_1292 NC_008601.1 1363305 1364576 R solute:sodium symporter complement(1363305..1364576) Francisella tularensis subsp. novicida U112 4547639 YP_898928.1 CDS rnhB NC_008601.1 1364577 1365134 R RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII complement(1364577..1365134) Francisella tularensis subsp. novicida U112 4547640 YP_898929.1 CDS FTN_1294 NC_008601.1 1365136 1365879 R rRNA methylase complement(1365136..1365879) Francisella tularensis subsp. novicida U112 4547641 YP_898930.1 CDS ptsN NC_008601.1 1365872 1366327 R PEP-dependent sugar PTS system family protein complement(1365872..1366327) Francisella tularensis subsp. novicida U112 4547642 YP_898931.1 CDS FTN_1296 NC_008601.1 1366364 1366660 R sigma54 modulation protein complement(1366364..1366660) Francisella tularensis subsp. novicida U112 4547643 YP_898932.1 CDS FTN_1297 NC_008601.1 1366779 1367024 D hypothetical protein 1366779..1367024 Francisella tularensis subsp. novicida U112 4548424 YP_898933.1 CDS trmE NC_008601.1 1367030 1368382 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1367030..1368382 Francisella tularensis subsp. novicida U112 4548425 YP_898934.1 CDS FTN_1299 NC_008601.1 1368392 1368586 R hypothetical protein complement(1368392..1368586) Francisella tularensis subsp. novicida U112 4548426 YP_898935.1 CDS FTN_1300 NC_008601.1 1368607 1369497 R LysR family transcriptional regulator complement(1368607..1369497) Francisella tularensis subsp. novicida U112 4548427 YP_898936.1 CDS FTN_1301 NC_008601.1 1369632 1370687 D choloylglycine hydrolase family protein 1369632..1370687 Francisella tularensis subsp. novicida U112 4548428 YP_898937.1 CDS cysK NC_008601.1 1370906 1371829 D cysteine synthase 1370906..1371829 Francisella tularensis subsp. novicida U112 4548429 YP_898938.1 CDS FTN_1303 NC_008601.1 1372091 1372660 D DsbB family disulfide bond formation protein 1372091..1372660 Francisella tularensis subsp. novicida U112 4548430 YP_898939.1 CDS pdpA NC_008601.1 1378294 1380756 D hypothetical protein 1378294..1380756 Francisella tularensis subsp. novicida U112 4548436 YP_898940.1 CDS pdpB NC_008601.1 1380761 1384042 D hypothetical protein 1380761..1384042 Francisella tularensis subsp. novicida U112 4548437 YP_898941.1 CDS FTN_1311 NC_008601.1 1384032 1384409 D hypothetical protein 1384032..1384409 Francisella tularensis subsp. novicida U112 4548438 YP_898942.1 CDS FTN_1312 NC_008601.1 1384422 1384916 D hypothetical protein 1384422..1384916 Francisella tularensis subsp. novicida U112 4548114 YP_898943.1 CDS FTN_1313 NC_008601.1 1384921 1386651 D hypothetical protein 1384921..1386651 Francisella tularensis subsp. novicida U112 4548115 YP_898944.1 CDS FTN_1314 NC_008601.1 1386652 1387173 D hypothetical protein 1386652..1387173 Francisella tularensis subsp. novicida U112 4548116 YP_898945.1 CDS FTN_1315 NC_008601.1 1387186 1388616 D hypothetical protein 1387186..1388616 Francisella tularensis subsp. novicida U112 4548117 YP_898946.1 CDS FTN_1316 NC_008601.1 1388629 1389252 D hypothetical protein 1388629..1389252 Francisella tularensis subsp. novicida U112 4548118 YP_898947.1 CDS FTN_1317 NC_008601.1 1389274 1390425 D hypothetical protein 1389274..1390425 Francisella tularensis subsp. novicida U112 4548119 YP_898948.1 CDS FTN_1318 NC_008601.1 1390391 1391164 D hypothetical protein 1390391..1391164 Francisella tularensis subsp. novicida U112 4548120 YP_898949.1 CDS pdpC NC_008601.1 1391204 1395181 D hypothetical protein 1391204..1395181 Francisella tularensis subsp. novicida U112 4548121 YP_898950.1 CDS FTN_1320 NC_008601.1 1395199 1395765 D hypothetical protein 1395199..1395765 Francisella tularensis subsp. novicida U112 4548122 YP_898951.1 CDS iglD NC_008601.1 1395772 1396968 R intracellular growth locus protein D complement(1395772..1396968) Francisella tularensis subsp. novicida U112 4548123 YP_898952.1 CDS iglC NC_008601.1 1396989 1397618 R intracellular growth locus protein C complement(1396989..1397618) Francisella tularensis subsp. novicida U112 4548124 YP_898953.1 CDS iglB NC_008601.1 1397635 1399155 R intracellular growth locus protein B complement(1397635..1399155) Francisella tularensis subsp. novicida U112 4548125 YP_898954.1 CDS iglA NC_008601.1 1399169 1399723 R intracellular growth locus protein A complement(1399169..1399723) Francisella tularensis subsp. novicida U112 4548126 YP_898955.1 CDS pdpD NC_008601.1 1399803 1403540 R hypothetical protein complement(1399803..1403540) Francisella tularensis subsp. novicida U112 4548127 YP_898956.1 CDS anmK NC_008601.1 1403641 1404786 R catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase complement(1403641..1404786) Francisella tularensis subsp. novicida U112 4548128 YP_898957.1 CDS treA NC_008601.1 1406119 1407573 D trehalase 1406119..1407573 Francisella tularensis subsp. novicida U112 4548130 YP_898958.1 CDS fbaA NC_008601.1 1407740 1408804 R class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis; fructose-1,6-bisphosphate aldolase complement(1407740..1408804) Francisella tularensis subsp. novicida U112 4548131 YP_898959.1 CDS pyk NC_008601.1 1408820 1410256 R pyruvate kinase complement(1408820..1410256) Francisella tularensis subsp. novicida U112 4548132 YP_898960.1 CDS pgk NC_008601.1 1410272 1411450 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(1410272..1411450) Francisella tularensis subsp. novicida U112 4547281 YP_898961.1 CDS gapA NC_008601.1 1411469 1412470 R glyceraldehyde-3-phosphate dehydrogenase complement(1411469..1412470) Francisella tularensis subsp. novicida U112 4547282 YP_898962.1 CDS tktA NC_008601.1 1412508 1414499 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(1412508..1414499) Francisella tularensis subsp. novicida U112 4547283 YP_898963.1 CDS FTN_1334 NC_008601.1 1414639 1415142 D hypothetical protein 1414639..1415142 Francisella tularensis subsp. novicida U112 4547284 YP_898964.1 CDS rpmF NC_008601.1 1415186 1415368 D some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1415186..1415368 Francisella tularensis subsp. novicida U112 4547285 YP_898965.1 CDS plsX NC_008601.1 1415467 1416513 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; putative glycerol-3-phosphate acyltransferase PlsX 1415467..1416513 Francisella tularensis subsp. novicida U112 4547286 YP_898966.1 CDS fabH NC_008601.1 1416610 1417581 D 3-oxoacyl-ACP synthase 1416610..1417581 Francisella tularensis subsp. novicida U112 4547287 YP_898967.1 CDS fabD NC_008601.1 1417629 1418549 D malonyl-CoA:ACP transacylase 1417629..1418549 Francisella tularensis subsp. novicida U112 4547288 YP_898968.1 CDS fabG NC_008601.1 1418563 1419306 D 3-oxoacyl-(acyl-carrier-protein) reductase 1418563..1419306 Francisella tularensis subsp. novicida U112 4547289 YP_898969.1 CDS acpP NC_008601.1 1419403 1419687 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1419403..1419687 Francisella tularensis subsp. novicida U112 4547290 YP_898970.1 CDS fabF NC_008601.1 1419767 1421026 D beta-ketoacyl-ACP synthase II 1419767..1421026 Francisella tularensis subsp. novicida U112 4547291 YP_898971.1 CDS FTN_1342 NC_008601.1 1421108 1421392 D hypothetical protein 1421108..1421392 Francisella tularensis subsp. novicida U112 4547292 YP_898972.1 CDS FTN_1343 NC_008601.1 1421382 1422068 R hypothetical protein complement(1421382..1422068) Francisella tularensis subsp. novicida U112 4547293 YP_898973.1 CDS FTN_1344 NC_008601.1 1422190 1423389 D hypothetical protein 1422190..1423389 Francisella tularensis subsp. novicida U112 4547294 YP_898974.1 CDS FTN_1345 NC_008601.1 1423503 1424555 D hypothetical protein 1423503..1424555 Francisella tularensis subsp. novicida U112 4547295 YP_898975.1 CDS FTN_1346 NC_008601.1 1424642 1425430 D inositol monophosphatase family protein 1424642..1425430 Francisella tularensis subsp. novicida U112 4547296 YP_898976.1 CDS sun NC_008601.1 1425430 1426710 D tRNA and rRNA cytosine-C5-methylases, sun protein 1425430..1426710 Francisella tularensis subsp. novicida U112 4547297 YP_898977.1 CDS FTN_1348 NC_008601.1 1426688 1427179 R acetyltransferase complement(1426688..1427179) Francisella tularensis subsp. novicida U112 4547298 YP_898978.1 CDS FTN_1349 NC_008601.1 1427272 1427817 R hypothetical protein complement(1427272..1427817) Francisella tularensis subsp. novicida U112 4547299 YP_898979.1 CDS ligA NC_008601.1 1427814 1429850 R DNA ligase complement(1427814..1429850) Francisella tularensis subsp. novicida U112 4547300 YP_898980.1 CDS FTN_1351 NC_008601.1 1430157 1430873 D hypothetical protein 1430157..1430873 Francisella tularensis subsp. novicida U112 4547908 YP_898981.1 CDS panB NC_008601.1 1430875 1431672 D catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 1430875..1431672 Francisella tularensis subsp. novicida U112 4547909 YP_898982.1 CDS panC NC_008601.1 1431659 1432444 D pantoate-beta-alanine ligase 1431659..1432444 Francisella tularensis subsp. novicida U112 4547910 YP_898983.1 CDS panD NC_008601.1 1432438 1432773 D Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate alpha-decarboxylase 1432438..1432773 Francisella tularensis subsp. novicida U112 4547911 YP_898984.1 CDS FTN_1355 NC_008601.1 1432777 1433547 D type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase 1432777..1433547 Francisella tularensis subsp. novicida U112 4547912 YP_898985.1 CDS recD NC_008601.1 1433559 1435358 R exodeoxyribonuclease V subunit alpha complement(1433559..1435358) Francisella tularensis subsp. novicida U112 4547913 YP_898986.1 CDS recB NC_008601.1 1435324 1438974 R ATP-dependent exonuclease V subunit beta complement(1435324..1438974) Francisella tularensis subsp. novicida U112 4547914 YP_898987.1 CDS FTN_1358 NC_008601.1 1439006 1439578 R hypothetical protein complement(1439006..1439578) Francisella tularensis subsp. novicida U112 4547915 YP_898988.1 CDS recC NC_008601.1 1439520 1442759 R exodeoxyribonuclease V subunit gamma complement(1439520..1442759) Francisella tularensis subsp. novicida U112 4547916 YP_898989.1 CDS gltB NC_008601.1 1442836 1444422 R glutamate synthase domain-containing 2 complement(1442836..1444422) Francisella tularensis subsp. novicida U112 4547917 YP_898990.1 CDS FTN_1361 NC_008601.1 1444600 1445469 D drug/metabolite exporter 1444600..1445469 Francisella tularensis subsp. novicida U112 4547918 YP_898991.1 CDS FTN_1362 NC_008601.1 1445483 1445869 R hypothetical protein complement(1445483..1445869) Francisella tularensis subsp. novicida U112 4547919 YP_898992.1 CDS FTN_1363 NC_008601.1 1446038 1446691 D prophage repressor protein 1446038..1446691 Francisella tularensis subsp. novicida U112 4547920 YP_898993.1 CDS FTN_1367 NC_008601.1 1447265 1448899 R hypothetical protein complement(1447265..1448899) Francisella tularensis subsp. novicida U112 4548274 YP_898994.1 CDS feoA NC_008601.1 1448916 1449140 R Fe2+ transport system protein A complement(1448916..1449140) Francisella tularensis subsp. novicida U112 4548275 YP_898995.1 CDS FTN_1369 NC_008601.1 1449249 1449956 D hypothetical protein 1449249..1449956 Francisella tularensis subsp. novicida U112 4548276 YP_898996.1 CDS gloB NC_008601.1 1450034 1450792 R hydroxyacylglutathione hydrolase complement(1450034..1450792) Francisella tularensis subsp. novicida U112 4548277 YP_898997.1 CDS FTN_1371 NC_008601.1 1450806 1451963 R hypothetical protein complement(1450806..1451963) Francisella tularensis subsp. novicida U112 4548278 YP_898998.1 CDS FTN_1372 NC_008601.1 1451960 1453045 R hypothetical protein complement(1451960..1453045) Francisella tularensis subsp. novicida U112 4548279 YP_898999.1 CDS hemD NC_008601.1 1453011 1453760 R uroporphyrinogen-III synthase complement(1453011..1453760) Francisella tularensis subsp. novicida U112 4548280 YP_899000.1 CDS sufE NC_008601.1 1453761 1454180 R sulfur acceptor protein SufE complement(1453761..1454180) Francisella tularensis subsp. novicida U112 4548281 YP_899001.1 CDS FTN_1376 NC_008601.1 1454884 1455420 D DsbB family disulfide bond formation protein 1454884..1455420 Francisella tularensis subsp. novicida U112 4548283 YP_899002.1 CDS proS NC_008601.1 1455684 1457381 D catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 1455684..1457381 Francisella tularensis subsp. novicida U112 4548284 YP_899003.1 CDS FTN_1378 NC_008601.1 1457390 1457929 D hypothetical protein 1457390..1457929 Francisella tularensis subsp. novicida U112 4548285 YP_899004.1 CDS FTN_1380 NC_008601.1 1459763 1460896 D aspartate/tyrosine/aromatic aminotransferase 1459763..1460896 Francisella tularensis subsp. novicida U112 4548287 YP_899005.1 CDS FTN_1381 NC_008601.1 1460964 1462382 D hypothetical protein 1460964..1462382 Francisella tularensis subsp. novicida U112 4548288 YP_899006.1 CDS FTN_1382 NC_008601.1 1462418 1462831 R hypothetical protein complement(1462418..1462831) Francisella tularensis subsp. novicida U112 4548289 YP_899007.1 CDS FTN_1383 NC_008601.1 1463001 1463771 D carbon-nitrogen hydrolase 1463001..1463771 Francisella tularensis subsp. novicida U112 4548290 YP_899008.1 CDS nusB NC_008601.1 1463755 1464180 R transcription termination factor complement(1463755..1464180) Francisella tularensis subsp. novicida U112 4548291 YP_899009.1 CDS FTN_1385 NC_008601.1 1464367 1464768 D hypothetical protein 1464367..1464768 Francisella tularensis subsp. novicida U112 4547833 YP_899010.1 CDS FTN_1386 NC_008601.1 1464785 1465297 D hypothetical protein 1464785..1465297 Francisella tularensis subsp. novicida U112 4547834 YP_899011.1 CDS FTN_1387 NC_008601.1 1465519 1465965 D hypothetical protein 1465519..1465965 Francisella tularensis subsp. novicida U112 4547835 YP_899012.1 CDS FTN_1388 NC_008601.1 1466005 1466625 D oxidoreductase 1466005..1466625 Francisella tularensis subsp. novicida U112 4547836 YP_899013.1 CDS FTN_1389 NC_008601.1 1466618 1467367 R hypothetical protein complement(1466618..1467367) Francisella tularensis subsp. novicida U112 4547837 YP_899014.1 CDS FTN_1390 NC_008601.1 1467369 1468055 R Zn-dependent hydrolase complement(1467369..1468055) Francisella tularensis subsp. novicida U112 4547838 YP_899015.1 CDS naoX NC_008601.1 1468100 1469791 R NAD(FAD)-dependent dehydrogenase complement(1468100..1469791) Francisella tularensis subsp. novicida U112 4547839 YP_899016.1 CDS FTN_1392 NC_008601.1 1469816 1470334 R rhodanese-related sulfurtransferase complement(1469816..1470334) Francisella tularensis subsp. novicida U112 4547840 YP_899017.1 CDS FTN_1393 NC_008601.1 1470396 1470698 R ArsR family transcriptional regulator complement(1470396..1470698) Francisella tularensis subsp. novicida U112 4547841 YP_899018.1 CDS FTN_1394 NC_008601.1 1471519 1471791 R hypothetical protein complement(1471519..1471791) Francisella tularensis subsp. novicida U112 4547842 YP_899019.1 CDS FTN_1395 NC_008601.1 1471772 1472776 R hypothetical protein complement(1471772..1472776) Francisella tularensis subsp. novicida U112 4547843 YP_899020.1 CDS FTN_1396 NC_008601.1 1472780 1473271 R endonuclease complement(1472780..1473271) Francisella tularensis subsp. novicida U112 4547844 YP_899021.1 CDS FTN_1397 NC_008601.1 1473442 1477344 R hypothetical protein complement(1473442..1477344) Francisella tularensis subsp. novicida U112 4547845 YP_899022.1 CDS FTN_1398 NC_008601.1 1477432 1477947 R acetyltransferase complement(1477432..1477947) Francisella tularensis subsp. novicida U112 4547846 YP_899023.1 CDS FTN_1399 NC_008601.1 1477952 1478668 R hypothetical protein complement(1477952..1478668) Francisella tularensis subsp. novicida U112 4547847 YP_899024.1 CDS trmB NC_008601.1 1478678 1479367 R tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase complement(1478678..1479367) Francisella tularensis subsp. novicida U112 4547848 YP_899025.1 CDS rhtB NC_008601.1 1479437 1480072 D homoserine/threonine efflux family protein 1479437..1480072 Francisella tularensis subsp. novicida U112 4547849 YP_899026.1 CDS ppnK NC_008601.1 1480069 1480959 R NAD kinase complement(1480069..1480959) Francisella tularensis subsp. novicida U112 4547850 YP_899027.1 CDS gtrB NC_008601.1 1481150 1482094 D glycosyl transferase family protein 1481150..1482094 Francisella tularensis subsp. novicida U112 4547851 YP_899028.1 CDS FTN_1404 NC_008601.1 1482098 1482877 R ATP-binding cassette (ABC) superfamily protein complement(1482098..1482877) Francisella tularensis subsp. novicida U112 4547852 YP_899029.1 CDS FTN_1405 NC_008601.1 1482886 1483809 R ABC transporter ATP-binding protein complement(1482886..1483809) Francisella tularensis subsp. novicida U112 4547780 YP_899030.1 CDS FTN_1406 NC_008601.1 1483910 1484686 R hypothetical protein complement(1483910..1484686) Francisella tularensis subsp. novicida U112 4547781 YP_899031.1 CDS FTN_1407 NC_008601.1 1484686 1485012 R hypothetical protein complement(1484686..1485012) Francisella tularensis subsp. novicida U112 4547782 YP_899032.1 CDS FTN_1408 NC_008601.1 1485138 1485905 R Mg-dependent DNase complement(1485138..1485905) Francisella tularensis subsp. novicida U112 4547783 YP_899033.1 CDS FTN_1409 NC_008601.1 1485988 1487373 R major facilitator transporter complement(1485988..1487373) Francisella tularensis subsp. novicida U112 4547784 YP_899034.1 CDS bfr NC_008601.1 1487622 1488062 D bacterioferritin 1487622..1488062 Francisella tularensis subsp. novicida U112 4547785 YP_899035.1 CDS FTN_1412 NC_008601.1 1488679 1489635 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(1488679..1489635) Francisella tularensis subsp. novicida U112 4547787 YP_899036.1 CDS FTN_1413 NC_008601.1 1489723 1490961 R related to the helicase subunit of the Holliday junction resolvase; recombination factor protein RarA complement(1489723..1490961) Francisella tularensis subsp. novicida U112 4547788 YP_899037.1 CDS ppx NC_008601.1 1491205 1492131 R exopolyphosphatase complement(1491205..1492131) Francisella tularensis subsp. novicida U112 4547789 YP_899038.1 CDS FTN_1415 NC_008601.1 1492329 1492652 D thioredoxin 1492329..1492652 Francisella tularensis subsp. novicida U112 4547790 YP_899039.1 CDS rho NC_008601.1 1492695 1493957 D An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 1492695..1493957 Francisella tularensis subsp. novicida U112 4547791 YP_899040.1 CDS manB NC_008601.1 1494297 1495781 R phosphomannomutase complement(1494297..1495781) Francisella tularensis subsp. novicida U112 4547792 YP_899041.1 CDS manC NC_008601.1 1495811 1497217 R mannose-1-phosphate guanylyltransferase complement(1495811..1497217) Francisella tularensis subsp. novicida U112 4547793 YP_899042.1 CDS wzx NC_008601.1 1498686 1499933 R O antigen flippase complement(1498686..1499933) Francisella tularensis subsp. novicida U112 4547795 YP_899043.1 CDS wbtH NC_008601.1 1499938 1501830 R glutamine amidotransferase/asparagine synthase complement(1499938..1501830) Francisella tularensis subsp. novicida U112 4547796 YP_899044.1 CDS wbtN NC_008601.1 1501832 1502944 R group 1 glycosyl transferase complement(1501832..1502944) Francisella tularensis subsp. novicida U112 4548348 YP_899045.1 CDS wbtG NC_008601.1 1502937 1504025 R group 1 glycosyl transferase complement(1502937..1504025) Francisella tularensis subsp. novicida U112 4548349 YP_899046.1 CDS FTN_1424 NC_008601.1 1503991 1505283 R hypothetical protein complement(1503991..1505283) Francisella tularensis subsp. novicida U112 4548350 YP_899047.1 CDS wbtF NC_008601.1 1505280 1506254 R NAD dependent epimerase complement(1505280..1506254) Francisella tularensis subsp. novicida U112 4548351 YP_899048.1 CDS wbtE NC_008601.1 1506254 1507564 R UDP-glucose/GDP-mannose dehydrogenase complement(1506254..1507564) Francisella tularensis subsp. novicida U112 4548352 YP_899049.1 CDS wbtD NC_008601.1 1507568 1508659 R group 1 glycosyl transferase complement(1507568..1508659) Francisella tularensis subsp. novicida U112 4548353 YP_899050.1 CDS wbtO NC_008601.1 1508656 1509267 R transferase complement(1508656..1509267) Francisella tularensis subsp. novicida U112 4548354 YP_899051.1 CDS wbtP NC_008601.1 1509257 1509886 R galactosyl transferase complement(1509257..1509886) Francisella tularensis subsp. novicida U112 4548355 YP_899052.1 CDS wbtQ NC_008601.1 1509876 1510991 R aminotransferase complement(1509876..1510991) Francisella tularensis subsp. novicida U112 4548356 YP_899053.1 CDS wbtA NC_008601.1 1510997 1512733 R dTDP-glucose 4,6-dehydratase complement(1510997..1512733) Francisella tularensis subsp. novicida U112 4548357 YP_899054.1 CDS hrpA NC_008601.1 1513192 1517211 R HrpA-like helicase complement(1513192..1517211) Francisella tularensis subsp. novicida U112 4548358 YP_899055.1 CDS FTN_1433 NC_008601.1 1517235 1518122 R hypothetical protein complement(1517235..1518122) Francisella tularensis subsp. novicida U112 4548359 YP_899056.1 CDS icd NC_008601.1 1518136 1520352 R isocitrate dehydrogenase complement(1518136..1520352) Francisella tularensis subsp. novicida U112 4548360 YP_899057.1 CDS FTN_1435 NC_008601.1 1520401 1520820 R arsenate reductase complement(1520401..1520820) Francisella tularensis subsp. novicida U112 4548361 YP_899058.1 CDS fadD NC_008601.1 1520964 1522652 D long chain fatty acid CoA ligase 1520964..1522652 Francisella tularensis subsp. novicida U112 4548362 YP_899059.1 CDS fadE NC_008601.1 1522690 1524930 D functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA; acyl-CoA dehydrogenase 1522690..1524930 Francisella tularensis subsp. novicida U112 4548363 YP_899060.1 CDS FTN_1438 NC_008601.1 1525003 1527699 D fusion product of 3-hydroxacyl-CoA dehydrogenase and acyl-CoA-binding protein 1525003..1527699 Francisella tularensis subsp. novicida U112 4548364 YP_899061.1 CDS fadA NC_008601.1 1527712 1528899 D Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 1527712..1528899 Francisella tularensis subsp. novicida U112 4548365 YP_899062.1 CDS FTN_1440 NC_008601.1 1528961 1529449 D hypothetical protein 1528961..1529449 Francisella tularensis subsp. novicida U112 4548366 YP_899063.1 CDS FTN_1441 NC_008601.1 1529442 1530722 R sugar porter (SP) family protein complement(1529442..1530722) Francisella tularensis subsp. novicida U112 4548367 YP_899064.1 CDS FTN_1442 NC_008601.1 1530872 1531099 R hypothetical protein complement(1530872..1531099) Francisella tularensis subsp. novicida U112 4547924 YP_899065.1 CDS FTN_1443 NC_008601.1 1531184 1532599 R putative nicotinate phosphoribosyltransferase complement(1531184..1532599) Francisella tularensis subsp. novicida U112 4547925 YP_899066.1 CDS FTN_1444 NC_008601.1 1532670 1533686 R mu-crystallin homolog; catalyzes the formation of L-proline from L-ornithine; ornithine cyclodeaminase complement(1532670..1533686) Francisella tularensis subsp. novicida U112 4547926 YP_899067.1 CDS FTN_1445 NC_008601.1 1533934 1534848 R hypothetical protein complement(1533934..1534848) Francisella tularensis subsp. novicida U112 4547927 YP_899068.1 CDS FTN_1446 NC_008601.1 1534988 1536382 R hypothetical protein complement(1534988..1536382) Francisella tularensis subsp. novicida U112 4547928 YP_899069.1 CDS FTN_1447 NC_008601.1 1536388 1537371 R hypothetical protein complement(1536388..1537371) Francisella tularensis subsp. novicida U112 4547929 YP_899070.1 CDS FTN_1448 NC_008601.1 1537382 1538812 R hypothetical protein complement(1537382..1538812) Francisella tularensis subsp. novicida U112 4547930 YP_899071.1 CDS FTN_1449 NC_008601.1 1538869 1539477 R hypothetical protein complement(1538869..1539477) Francisella tularensis subsp. novicida U112 4547931 YP_899072.1 CDS FTN_1450 NC_008601.1 1539652 1540053 R hypothetical protein complement(1539652..1540053) Francisella tularensis subsp. novicida U112 4547932 YP_899073.1 CDS FTN_1451 NC_008601.1 1540171 1540707 R hypothetical protein complement(1540171..1540707) Francisella tularensis subsp. novicida U112 4547933 YP_899074.1 CDS FTN_1452 NC_008601.1 1540850 1541539 D two-component response regulator 1540850..1541539 Francisella tularensis subsp. novicida U112 4547934 YP_899075.1 CDS FTN_1453 NC_008601.1 1541523 1542560 D two-component regulator, sensor histidine kinase 1541523..1542560 Francisella tularensis subsp. novicida U112 4547935 YP_899076.1 CDS FTN_1454 NC_008601.1 1542637 1543890 D NAD/FAD-binding protein 1542637..1543890 Francisella tularensis subsp. novicida U112 4547936 YP_899077.1 CDS FTN_1455 NC_008601.1 1543884 1544660 D hypothetical protein 1543884..1544660 Francisella tularensis subsp. novicida U112 4547937 YP_899078.1 CDS cfa NC_008601.1 1544780 1545943 D cyclopropane fatty acid synthase, methyltransferase 1544780..1545943 Francisella tularensis subsp. novicida U112 4547938 YP_899079.1 CDS FTN_1457 NC_008601.1 1545936 1546454 D hypothetical protein 1545936..1546454 Francisella tularensis subsp. novicida U112 4547939 YP_899080.1 CDS FTN_1458 NC_008601.1 1546487 1546993 D hypothetical protein 1546487..1546993 Francisella tularensis subsp. novicida U112 4547940 YP_899081.1 CDS FTN_1459 NC_008601.1 1546995 1547738 D short chain dehydrogenase 1546995..1547738 Francisella tularensis subsp. novicida U112 4547941 YP_899082.1 CDS FTN_1460 NC_008601.1 1547752 1548582 D delta 9 acyl-lipid fatty acid desaturase 1547752..1548582 Francisella tularensis subsp. novicida U112 4547942 YP_899083.1 CDS rnr NC_008601.1 1548606 1550903 R ribonuclease R complement(1548606..1550903) Francisella tularensis subsp. novicida U112 4548556 YP_899084.1 CDS truB NC_008601.1 1550896 1551804 R catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B complement(1550896..1551804) Francisella tularensis subsp. novicida U112 4548557 YP_899085.1 CDS rnc NC_008601.1 1551791 1552483 R cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III complement(1551791..1552483) Francisella tularensis subsp. novicida U112 4548558 YP_899086.1 CDS lepB NC_008601.1 1552490 1553353 R signal peptidase I complement(1552490..1553353) Francisella tularensis subsp. novicida U112 4548559 YP_899087.1 CDS FTN_1465 NC_008601.1 1553358 1554044 R two-component response regulator complement(1553358..1554044) Francisella tularensis subsp. novicida U112 4548560 YP_899088.1 CDS FTN_1466 NC_008601.1 1554485 1555576 R hypothetical protein complement(1554485..1555576) Francisella tularensis subsp. novicida U112 4548561 YP_899089.1 CDS proC NC_008601.1 1555813 1556637 R pyrroline-5-carboxylate reductase complement(1555813..1556637) Francisella tularensis subsp. novicida U112 4548562 YP_899090.1 CDS FTN_1468 NC_008601.1 1556744 1557322 D HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; putative deoxyribonucleotide triphosphate pyrophosphatase 1556744..1557322 Francisella tularensis subsp. novicida U112 4548563 YP_899091.1 CDS kdtA NC_008601.1 1557427 1558722 D 3-deoxy-D-manno-octulosonic-acid transferase 1557427..1558722 Francisella tularensis subsp. novicida U112 4548564 YP_899092.1 CDS ispA NC_008601.1 1558719 1559600 D geranyl diphosphate synthase/farnesyl diphosphate synthase 1558719..1559600 Francisella tularensis subsp. novicida U112 4548565 YP_899093.1 CDS pcs NC_008601.1 1559648 1560412 D phosphatidylcholine synthase 1559648..1560412 Francisella tularensis subsp. novicida U112 4548566 YP_899094.1 CDS FTN_1472 NC_008601.1 1560482 1561291 D hypothetical protein 1560482..1561291 Francisella tularensis subsp. novicida U112 4548567 YP_899095.1 CDS bglX NC_008601.1 1561671 1562807 R glycosyl hydrolase family protein complement(1561671..1562807) Francisella tularensis subsp. novicida U112 4548569 YP_899096.1 CDS FTN_1475 NC_008601.1 1563109 1563483 R hypothetical protein complement(1563109..1563483) Francisella tularensis subsp. novicida U112 4548570 YP_899097.1 CDS FTN_1476 NC_008601.1 1563574 1564161 R hypothetical protein complement(1563574..1564161) Francisella tularensis subsp. novicida U112 4548571 YP_899098.1 CDS lpxB NC_008601.1 1564221 1565363 R catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase complement(1564221..1565363) Francisella tularensis subsp. novicida U112 4548572 YP_899099.1 CDS lpxA NC_008601.1 1565363 1566142 R catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase complement(1565363..1566142) Francisella tularensis subsp. novicida U112 4548573 YP_899100.1 CDS fabZ NC_008601.1 1566145 1566636 R in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase complement(1566145..1566636) Francisella tularensis subsp. novicida U112 4548574 YP_899101.1 CDS lpxD NC_008601.1 1566651 1567664 R adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase complement(1566651..1567664) Francisella tularensis subsp. novicida U112 4548518 YP_899102.1 CDS ompH NC_008601.1 1567683 1568186 R outer membrane protein OmpH complement(1567683..1568186) Francisella tularensis subsp. novicida U112 4548519 YP_899103.1 CDS FTN_1482 NC_008601.1 1568322 1570700 R hypothetical protein complement(1568322..1570700) Francisella tularensis subsp. novicida U112 4548520 YP_899104.1 CDS dxr NC_008601.1 1570706 1571863 R catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase complement(1570706..1571863) Francisella tularensis subsp. novicida U112 4548521 YP_899105.1 CDS gyrA NC_008601.1 1571869 1574475 R DNA gyrase subunit A complement(1571869..1574475) Francisella tularensis subsp. novicida U112 4548522 YP_899106.1 CDS cbpA NC_008601.1 1574733 1576400 D chitin-binding protein 1574733..1576400 Francisella tularensis subsp. novicida U112 4548523 YP_899107.1 CDS ung NC_008601.1 1576434 1577096 R Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase complement(1576434..1577096) Francisella tularensis subsp. novicida U112 4548524 YP_899108.1 CDS FTN_1487 NC_008601.1 1577093 1579960 R restriction endonuclease complement(1577093..1579960) Francisella tularensis subsp. novicida U112 4548525 YP_899109.1 CDS FTN_1488 NC_008601.1 1579950 1580906 R prophage maintenance system killer protein (DOC) complement(1579950..1580906) Francisella tularensis subsp. novicida U112 4548526 YP_899110.1 CDS FTN_1489 NC_008601.1 1581018 1581764 R hypothetical protein complement(1581018..1581764) Francisella tularensis subsp. novicida U112 4548527 YP_899111.1 CDS FTN_1490 NC_008601.1 1581776 1582627 R hypothetical protein complement(1581776..1582627) Francisella tularensis subsp. novicida U112 4548528 YP_899112.1 CDS FTN_1491 NC_008601.1 1582627 1584609 R adenine specific DNA methylase complement(1582627..1584609) Francisella tularensis subsp. novicida U112 4548529 YP_899113.1 CDS lpdA NC_008601.1 1584791 1586203 R dihydrolipoamide dehydrogenase complement(1584791..1586203) Francisella tularensis subsp. novicida U112 4548530 YP_899114.1 CDS aceF NC_008601.1 1586217 1588112 R E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; dihydrolipoamide acetyltransferase complement(1586217..1588112) Francisella tularensis subsp. novicida U112 4548531 YP_899115.1 CDS aceE NC_008601.1 1588130 1590811 R E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 complement(1588130..1590811) Francisella tularensis subsp. novicida U112 4548532 YP_899116.1 CDS FTN_1495 NC_008601.1 1591111 1592298 R hypothetical protein complement(1591111..1592298) Francisella tularensis subsp. novicida U112 4548533 YP_899117.1 CDS coaE NC_008601.1 1592378 1592992 D catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 1592378..1592992 Francisella tularensis subsp. novicida U112 4548534 YP_899118.1 CDS trpS NC_008601.1 1593289 1594293 D catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 1593289..1594293 Francisella tularensis subsp. novicida U112 4547339 YP_899119.1 CDS FTN_1500 NC_008601.1 1594295 1595020 D hypothetical protein 1594295..1595020 Francisella tularensis subsp. novicida U112 4547340 YP_899120.1 CDS FTN_1501 NC_008601.1 1595030 1596328 D monovalent cation:proton antiporter-1 1595030..1596328 Francisella tularensis subsp. novicida U112 4547341 YP_899121.1 CDS FTN_1502 NC_008601.1 1596727 1597764 R hypothetical protein complement(1596727..1597764) Francisella tularensis subsp. novicida U112 4547342 YP_899122.1 CDS FTN_1503 NC_008601.1 1598261 1598656 R hypothetical protein complement(1598261..1598656) Francisella tularensis subsp. novicida U112 4547343 YP_899123.1 CDS murQ NC_008601.1 1598658 1599542 R catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase complement(1598658..1599542) Francisella tularensis subsp. novicida U112 4547344 YP_899124.1 CDS FTN_1505 NC_008601.1 1599539 1601503 R hypothetical protein complement(1599539..1601503) Francisella tularensis subsp. novicida U112 4547345 YP_899125.1 CDS FTN_1506 NC_008601.1 1601512 1602525 R hypothetical protein complement(1601512..1602525) Francisella tularensis subsp. novicida U112 4547346 YP_899126.1 CDS FTN_1507 NC_008601.1 1602506 1603009 R hypothetical protein complement(1602506..1603009) Francisella tularensis subsp. novicida U112 4547347 YP_899127.1 CDS accA NC_008601.1 1603029 1603976 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha complement(1603029..1603976) Francisella tularensis subsp. novicida U112 4547348 YP_899128.1 CDS mutS NC_008601.1 1604143 1606677 D This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 1604143..1606677 Francisella tularensis subsp. novicida U112 4547349 YP_899129.1 CDS secB2 NC_008601.1 1606754 1607197 D molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 1606754..1607197 Francisella tularensis subsp. novicida U112 4547350 YP_899130.1 CDS FTN_1511 NC_008601.1 1607392 1608615 D hypothetical protein 1607392..1608615 Francisella tularensis subsp. novicida U112 4547351 YP_899131.1 CDS FTN_1512 NC_008601.1 1608678 1609850 D hydroxy/aromatic amino acid permease (HAAAP) family protein 1608678..1609850 Francisella tularensis subsp. novicida U112 4547352 YP_899132.1 CDS xerC NC_008601.1 1609860 1610738 D site-specific recombinase 1609860..1610738 Francisella tularensis subsp. novicida U112 4547353 YP_899133.1 CDS FTN_1514 NC_008601.1 1610738 1611463 D hypothetical protein 1610738..1611463 Francisella tularensis subsp. novicida U112 4547354 YP_899134.1 CDS FTN_1515 NC_008601.1 1611470 1612084 R hypothetical protein complement(1611470..1612084) Francisella tularensis subsp. novicida U112 4547355 YP_899135.1 CDS FTN_1516 NC_008601.1 1612172 1612750 D hypothetical protein 1612172..1612750 Francisella tularensis subsp. novicida U112 4547356 YP_899136.1 CDS FTN_1517 NC_008601.1 1612827 1613459 D hypothetical protein 1612827..1613459 Francisella tularensis subsp. novicida U112 4548170 YP_899137.1 CDS relA NC_008601.1 1614438 1616447 R GDP pyrophosphokinase/GTP pyrophosphokinase complement(1614438..1616447) Francisella tularensis subsp. novicida U112 4548171 YP_899138.1 CDS FTN_1519 NC_008601.1 1616750 1617106 R hypothetical protein complement(1616750..1617106) Francisella tularensis subsp. novicida U112 4548172 YP_899139.1 CDS FTN_1520 NC_008601.1 1617140 1618336 R hydroxy/aromatic amino acid permease (HAAAP) family protein complement(1617140..1618336) Francisella tularensis subsp. novicida U112 4548173 YP_899140.1 CDS FTN_1521 NC_008601.1 1618541 1619425 D drug/metabolite exporter protein 1618541..1619425 Francisella tularensis subsp. novicida U112 4548174 YP_899141.1 CDS FTN_1522 NC_008601.1 1619415 1620341 R subunit of DnaJ/DnaK/GrpE complement(1619415..1620341) Francisella tularensis subsp. novicida U112 4548175 YP_899142.1 CDS FTN_1523 NC_008601.1 1620541 1621254 D amino acid-polyamine-organocation family protein 1620541..1621254 Francisella tularensis subsp. novicida U112 4548176 YP_899143.1 CDS FTN_1524 NC_008601.1 1621269 1621652 R hypothetical protein complement(1621269..1621652) Francisella tularensis subsp. novicida U112 4548177 YP_899144.1 CDS FTN_1525 NC_008601.1 1621649 1622248 R phosphatidyltransferase complement(1621649..1622248) Francisella tularensis subsp. novicida U112 4548178 YP_899145.1 CDS FTN_1526 NC_008601.1 1622245 1623663 R dihydrolipoamide dehydrogenase complement(1622245..1623663) Francisella tularensis subsp. novicida U112 4548179 YP_899146.1 CDS FTN_1527 NC_008601.1 1623666 1624385 R hypothetical protein complement(1623666..1624385) Francisella tularensis subsp. novicida U112 4548180 YP_899147.1 CDS FTN_1528 NC_008601.1 1624415 1624978 D methylated-DNA--protein-cysteine methyltransferase 1624415..1624978 Francisella tularensis subsp. novicida U112 4548181 YP_899148.1 CDS FTN_1529 NC_008601.1 1625380 1626783 R APC family gamma-glutamate:GABA antiporter complement(1625380..1626783) Francisella tularensis subsp. novicida U112 4548182 YP_899149.1 CDS lysA NC_008601.1 1626795 1627979 R diaminopimelate decarboxylase complement(1626795..1627979) Francisella tularensis subsp. novicida U112 4548183 YP_899150.1 CDS FTN_1531 NC_008601.1 1627992 1628675 R hypothetical protein complement(1627992..1628675) Francisella tularensis subsp. novicida U112 4548184 YP_899151.1 CDS gdhA NC_008601.1 1629170 1630519 D converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1629170..1630519 Francisella tularensis subsp. novicida U112 4548185 YP_899152.1 CDS FTN_1533 NC_008601.1 1630614 1631804 D hypothetical protein 1630614..1631804 Francisella tularensis subsp. novicida U112 4548186 YP_899153.1 CDS FTN_1534 NC_008601.1 1631854 1632324 D hypothetical protein 1631854..1632324 Francisella tularensis subsp. novicida U112 4548187 YP_899154.1 CDS FTN_1535 NC_008601.1 1632461 1633285 D short chain dehydrogenase 1632461..1633285 Francisella tularensis subsp. novicida U112 4548897 YP_899155.1 CDS FTN_1536 NC_008601.1 1633307 1634656 R amino acid-polyamine-organocation (APC) superfamily protein complement(1633307..1634656) Francisella tularensis subsp. novicida U112 4548898 YP_899156.1 CDS FTN_1537 NC_008601.1 1635778 1636650 R hypothetical protein complement(1635778..1636650) Francisella tularensis subsp. novicida U112 4548899 YP_899157.1 CDS groEL NC_008601.1 1636881 1638515 R 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL complement(1636881..1638515) Francisella tularensis subsp. novicida U112 4548900 YP_899158.1 CDS groES NC_008601.1 1638553 1638840 R 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES complement(1638553..1638840) Francisella tularensis subsp. novicida U112 4548901 YP_899159.1 CDS FTN_1540 NC_008601.1 1639091 1639525 D hypothetical protein 1639091..1639525 Francisella tularensis subsp. novicida U112 4548902 YP_899160.1 CDS FTN_1542 NC_008601.1 1640166 1640930 D hypothetical protein 1640166..1640930 Francisella tularensis subsp. novicida U112 4548904 YP_899161.1 CDS FTN_1543 NC_008601.1 1640934 1641401 D hypothetical protein 1640934..1641401 Francisella tularensis subsp. novicida U112 4548905 YP_899162.1 CDS hemK NC_008601.1 1641392 1642246 R HemK family modification methylase complement(1641392..1642246) Francisella tularensis subsp. novicida U112 4548906 YP_899163.1 CDS prfA NC_008601.1 1642239 1643324 R recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 complement(1642239..1643324) Francisella tularensis subsp. novicida U112 4548907 YP_899164.1 CDS hemA NC_008601.1 1643325 1644569 R catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase complement(1643325..1644569) Francisella tularensis subsp. novicida U112 4548908 YP_899165.1 CDS FTN_1547 NC_008601.1 1644749 1645387 D hypothetical protein 1644749..1645387 Francisella tularensis subsp. novicida U112 4548909 YP_899166.1 CDS FTN_1548 NC_008601.1 1645390 1646760 D hypothetical protein 1645390..1646760 Francisella tularensis subsp. novicida U112 4548910 YP_899167.1 CDS FTN_1549 NC_008601.1 1646760 1647941 D drug:H+ antiporter-1 (DHA1) family protein 1646760..1647941 Francisella tularensis subsp. novicida U112 4548911 YP_899168.1 CDS parE NC_008601.1 1648031 1649914 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 1648031..1649914 Francisella tularensis subsp. novicida U112 4548912 YP_899169.1 CDS ampD NC_008601.1 1649963 1650487 R N-acetyl-anhydromuranmyl-L-alanine amidase complement(1649963..1650487) Francisella tularensis subsp. novicida U112 4548913 YP_899170.1 CDS FTN_1552 NC_008601.1 1650561 1651187 D acid phosphatase 1650561..1651187 Francisella tularensis subsp. novicida U112 4548914 YP_899171.1 CDS nudH NC_008601.1 1651197 1651661 R hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase complement(1651197..1651661) Francisella tularensis subsp. novicida U112 4548439 YP_899172.1 CDS FTN_1554 NC_008601.1 1651824 1653344 D hypothetical protein 1651824..1653344 Francisella tularensis subsp. novicida U112 4548440 YP_899173.1 CDS FTN_1555 NC_008601.1 1653462 1654346 D licB-like transmembrane protein 1653462..1654346 Francisella tularensis subsp. novicida U112 4548441 YP_899174.1 CDS FTN_1556 NC_008601.1 1654343 1654927 R acid phosphatase complement(1654343..1654927) Francisella tularensis subsp. novicida U112 4548442 YP_899175.1 CDS FTN_1557 NC_008601.1 1654932 1655777 R oxidoreductase iron/ascorbate family protein complement(1654932..1655777) Francisella tularensis subsp. novicida U112 4548443 YP_899176.1 CDS xerD NC_008601.1 1655900 1656778 R site-specific recombinase complement(1655900..1656778) Francisella tularensis subsp. novicida U112 4548444 YP_899177.1 CDS rplS NC_008601.1 1656944 1657291 R this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 complement(1656944..1657291) Francisella tularensis subsp. novicida U112 4548445 YP_899178.1 CDS trmD NC_008601.1 1657291 1658049 R methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(1657291..1658049) Francisella tularensis subsp. novicida U112 4548446 YP_899179.1 CDS rimM NC_008601.1 1658454 1658963 R Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM complement(1658454..1658963) Francisella tularensis subsp. novicida U112 4548447 YP_899180.1 CDS rpsP NC_008601.1 1659007 1659255 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(1659007..1659255) Francisella tularensis subsp. novicida U112 4548448 YP_899181.1 CDS metK NC_008601.1 1659549 1660709 D catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 1659549..1660709 Francisella tularensis subsp. novicida U112 4548449 YP_899182.1 CDS FTN_1564 NC_008601.1 1660920 1662086 R fatty acid desaturase complement(1660920..1662086) Francisella tularensis subsp. novicida U112 4548450 YP_899183.1 CDS gcp NC_008601.1 1662200 1663210 R in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease complement(1662200..1663210) Francisella tularensis subsp. novicida U112 4548451 YP_899184.1 CDS FTN_1566 NC_008601.1 1663210 1663446 R hypothetical protein complement(1663210..1663446) Francisella tularensis subsp. novicida U112 4548452 YP_899185.1 CDS rpoC NC_008601.1 1663549 1667802 R DNA-directed RNA polymerase, beta' subunit/160 kD subunit complement(1663549..1667802) Francisella tularensis subsp. novicida U112 4548453 YP_899186.1 CDS rpoB NC_008601.1 1667864 1671940 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta complement(1667864..1671940) Francisella tularensis subsp. novicida U112 4548454 YP_899187.1 CDS rplL NC_008601.1 1672094 1672471 R present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 complement(1672094..1672471) Francisella tularensis subsp. novicida U112 4548455 YP_899188.1 CDS rplJ NC_008601.1 1672534 1673052 R binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 complement(1672534..1673052) Francisella tularensis subsp. novicida U112 4548456 YP_899189.1 CDS rplA NC_008601.1 1673222 1673917 R in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 complement(1673222..1673917) Francisella tularensis subsp. novicida U112 4548457 YP_899190.1 CDS rplK NC_008601.1 1673920 1674354 R binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 complement(1673920..1674354) Francisella tularensis subsp. novicida U112 4548915 YP_899191.1 CDS nusG NC_008601.1 1674423 1674956 R transcription antitermination protein nusG complement(1674423..1674956) Francisella tularensis subsp. novicida U112 4548916 YP_899192.1 CDS secE NC_008601.1 1674972 1675442 R forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE complement(1674972..1675442) Francisella tularensis subsp. novicida U112 4548917 YP_899193.1 CDS tufA NC_008601.1 1675634 1676818 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(1675634..1676818) Francisella tularensis subsp. novicida U112 4548919 YP_899194.1 CDS FTN_1580 NC_008601.1 1677283 1678698 R DNA helicase complement(1677283..1678698) Francisella tularensis subsp. novicida U112 4548923 YP_899195.1 CDS FTN_1581 NC_008601.1 1678698 1679195 R small conductance mechanosensitive ion channel (MscS) family protein complement(1678698..1679195) Francisella tularensis subsp. novicida U112 4548924 YP_899196.1 CDS FTN_1582 NC_008601.1 1679173 1679886 R hypothetical protein complement(1679173..1679886) Francisella tularensis subsp. novicida U112 4548925 YP_899197.1 CDS glpF NC_008601.1 1679890 1680654 R glycerol uptake facilitator protein complement(1679890..1680654) Francisella tularensis subsp. novicida U112 4548926 YP_899198.1 CDS glpD NC_008601.1 1680664 1682196 R glycerol-3-phosphate dehydrogenase complement(1680664..1682196) Francisella tularensis subsp. novicida U112 4548927 YP_899199.1 CDS glpK NC_008601.1 1682445 1683947 R glycerol kinase complement(1682445..1683947) Francisella tularensis subsp. novicida U112 4548928 YP_899200.1 CDS FTN_1586 NC_008601.1 1684004 1685317 R major facilitator superfamily sugar transporter complement(1684004..1685317) Francisella tularensis subsp. novicida U112 4548929 YP_899201.1 CDS FTN_1587 NC_008601.1 1685387 1685998 R hypothetical protein complement(1685387..1685998) Francisella tularensis subsp. novicida U112 4548877 YP_899202.1 CDS FTN_1588 NC_008601.1 1686132 1687334 D major facilitator transporter 1686132..1687334 Francisella tularensis subsp. novicida U112 4548878 YP_899203.1 CDS oppF NC_008601.1 1687338 1688312 R peptide/opine/nickel uptake transporter (PepT) family protein complement(1687338..1688312) Francisella tularensis subsp. novicida U112 4548879 YP_899204.1 CDS oppD NC_008601.1 1688313 1689281 R peptide/opine/nickel uptake transporter (PepT) family protein complement(1688313..1689281) Francisella tularensis subsp. novicida U112 4548880 YP_899205.1 CDS oppC NC_008601.1 1689285 1690145 R peptide/opine/nickel uptake transporter (PepT) family protein complement(1689285..1690145) Francisella tularensis subsp. novicida U112 4548881 YP_899206.1 CDS oppB NC_008601.1 1690145 1691083 R peptide/opine/nickel uptake transporter (PepT) family protein complement(1690145..1691083) Francisella tularensis subsp. novicida U112 4548882 YP_899207.1 CDS oppA NC_008601.1 1691108 1692784 R oligopeptide ABC transporter periplasmic protein complement(1691108..1692784) Francisella tularensis subsp. novicida U112 4548883 YP_899208.1 CDS uvrD NC_008601.1 1692874 1695096 R DNA helicase II complement(1692874..1695096) Francisella tularensis subsp. novicida U112 4548884 YP_899209.1 CDS ftsY NC_008601.1 1695187 1696182 R cell division protein, signal recognition particle GTPase complement(1695187..1696182) Francisella tularensis subsp. novicida U112 4548885 YP_899210.1 CDS fimV NC_008601.1 1696215 1697531 R Type IV pili, pilus assembly protein complement(1696215..1697531) Francisella tularensis subsp. novicida U112 4548886 YP_899211.1 CDS prfC NC_008601.1 1697606 1699183 R stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 complement(1697606..1699183) Francisella tularensis subsp. novicida U112 4548887 YP_899212.1 CDS tmk NC_008601.1 1699245 1699874 R catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase complement(1699245..1699874) Francisella tularensis subsp. novicida U112 4548888 YP_899213.1 CDS nupC NC_008601.1 1699887 1701089 R nucleoside permease NUP family protein complement(1699887..1701089) Francisella tularensis subsp. novicida U112 4548889 YP_899214.1 CDS nupC1 NC_008601.1 1701108 1702307 R nucleoside permease NUP family protein complement(1701108..1702307) Francisella tularensis subsp. novicida U112 4548890 YP_899215.1 CDS deoC NC_008601.1 1702297 1703058 R deoxyribose-phosphate aldolase complement(1702297..1703058) Francisella tularensis subsp. novicida U112 4548891 YP_899216.1 CDS deoB NC_008601.1 1703021 1704265 R catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase complement(1703021..1704265) Francisella tularensis subsp. novicida U112 4548892 YP_899217.1 CDS FTN_1603 NC_008601.1 1704270 1705046 R type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase complement(1704270..1705046) Francisella tularensis subsp. novicida U112 4548893 YP_899218.1 CDS polA NC_008601.1 1705066 1707759 R DNA polymerase I complement(1705066..1707759) Francisella tularensis subsp. novicida U112 4548894 YP_899219.1 CDS lpxK NC_008601.1 1707855 1708823 R transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase complement(1707855..1708823) Francisella tularensis subsp. novicida U112 4548895 YP_899220.1 CDS msbA NC_008601.1 1708829 1710658 R lipid exporter (LipidE) family protein complement(1708829..1710658) Francisella tularensis subsp. novicida U112 4548896 YP_899221.1 CDS cca NC_008601.1 1710763 1711872 D catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity; tRNA CCA-pyrophosphorylase 1710763..1711872 Francisella tularensis subsp. novicida U112 4547209 YP_899222.1 CDS dsbB NC_008601.1 1711912 1712403 D disulfide bond formation protein 1711912..1712403 Francisella tularensis subsp. novicida U112 4547210 YP_899223.1 CDS FTN_1609 NC_008601.1 1712416 1713789 D membrane fusion protein 1712416..1713789 Francisella tularensis subsp. novicida U112 4547211 YP_899224.1 CDS FTN_1610 NC_008601.1 1713789 1716902 D RND efflux transporter 1713789..1716902 Francisella tularensis subsp. novicida U112 4547212 YP_899225.1 CDS FTN_1611 NC_008601.1 1717771 1719051 D major facilitator transporter 1717771..1719051 Francisella tularensis subsp. novicida U112 4547213 YP_899226.1 CDS FTN_1612 NC_008601.1 1719296 1719877 D hypothetical protein 1719296..1719877 Francisella tularensis subsp. novicida U112 4547214 YP_899227.1 CDS FTN_1613 NC_008601.1 1720107 1721120 R U61 family peptidase complement(1720107..1721120) Francisella tularensis subsp. novicida U112 4547215 YP_899228.1 CDS FTN_1615 NC_008601.1 1724058 1725338 R hypothetical protein complement(1724058..1725338) Francisella tularensis subsp. novicida U112 4547217 YP_899229.1 CDS FTN_1616 NC_008601.1 1725342 1726298 R hypothetical protein complement(1725342..1726298) Francisella tularensis subsp. novicida U112 4547218 YP_899230.1 CDS FTN_1617 NC_008601.1 1726414 1727841 D two-component regulator, sensor histidine kinase 1726414..1727841 Francisella tularensis subsp. novicida U112 4547219 YP_899231.1 CDS FTN_1618 NC_008601.1 1727838 1728719 R hypothetical protein complement(1727838..1728719) Francisella tularensis subsp. novicida U112 4547220 YP_899232.1 CDS appC NC_008601.1 1728955 1730331 D cytochrome bd-II terminal oxidase subunit I 1728955..1730331 Francisella tularensis subsp. novicida U112 4547221 YP_899233.1 CDS appB NC_008601.1 1730335 1731297 D cytochrome bd-II terminal oxidase subunit II 1730335..1731297 Francisella tularensis subsp. novicida U112 4547222 YP_899234.1 CDS FTN_1621 NC_008601.1 1731751 1732737 D NAD/FAD-dependent oxidoreductase 1731751..1732737 Francisella tularensis subsp. novicida U112 4547223 YP_899235.1 CDS pilT NC_008601.1 1732817 1733845 R Type IV pili nucleotide-binding protein complement(1732817..1733845) Francisella tularensis subsp. novicida U112 4548001 YP_899236.1 CDS acnA NC_008601.1 1733940 1736753 R Catalyzes the conversion of citrate to isocitrate; aconitate hydratase complement(1733940..1736753) Francisella tularensis subsp. novicida U112 4548002 YP_899237.1 CDS FTN_1624 NC_008601.1 1736858 1737736 R hypothetical protein complement(1736858..1737736) Francisella tularensis subsp. novicida U112 4548003 YP_899238.1 CDS FTN_1625 NC_008601.1 1737806 1738183 D hypothetical protein 1737806..1738183 Francisella tularensis subsp. novicida U112 4548004 YP_899239.1 CDS hemN NC_008601.1 1738188 1739330 D coproporphyrinogen III oxidase, anaerobic 1738188..1739330 Francisella tularensis subsp. novicida U112 4548005 YP_899240.1 CDS FTN_1627 NC_008601.1 1739327 1739779 R hypothetical protein complement(1739327..1739779) Francisella tularensis subsp. novicida U112 4548006 YP_899241.1 CDS FTN_1628 NC_008601.1 1739838 1740791 R LysR family transcriptional regulator complement(1739838..1740791) Francisella tularensis subsp. novicida U112 4548007 YP_899242.1 CDS secG NC_008601.1 1740961 1741314 R preprotein translocase subunit SecG complement(1740961..1741314) Francisella tularensis subsp. novicida U112 4548009 YP_899243.1 CDS tpiA NC_008601.1 1741302 1742063 R Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase complement(1741302..1742063) Francisella tularensis subsp. novicida U112 4548010 YP_899244.1 CDS glmM NC_008601.1 1742066 1743397 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(1742066..1743397) Francisella tularensis subsp. novicida U112 4548011 YP_899245.1 CDS apt NC_008601.1 1743408 1743935 R catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase complement(1743408..1743935) Francisella tularensis subsp. novicida U112 4548012 YP_899246.1 CDS sucB NC_008601.1 1743975 1745444 R 2-oxoglutarate dehydrogenase complex, E2 component, dihydrolipoyltranssuccinase complement(1743975..1745444) Francisella tularensis subsp. novicida U112 4548013 YP_899247.1 CDS sucA NC_008601.1 1745470 1748283 R SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component complement(1745470..1748283) Francisella tularensis subsp. novicida U112 4548014 YP_899248.1 CDS sdhB NC_008601.1 1748313 1749014 R part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit complement(1748313..1749014) Francisella tularensis subsp. novicida U112 4548015 YP_899249.1 CDS sdhA NC_008601.1 1749032 1750825 R succinate dehydrogenase flavoprotein complement(1749032..1750825) Francisella tularensis subsp. novicida U112 4548016 YP_899250.1 CDS sdhD NC_008601.1 1750838 1751206 R succinate dehydrogenase hydrophobic membrane anchor protein complement(1750838..1751206) Francisella tularensis subsp. novicida U112 4548017 YP_899251.1 CDS sdhC NC_008601.1 1751182 1751655 R succinate dehydrogenase, cytochrome b556 complement(1751182..1751655) Francisella tularensis subsp. novicida U112 4548018 YP_899252.1 CDS gltA NC_008601.1 1751913 1753172 D citrate synthase 1751913..1753172 Francisella tularensis subsp. novicida U112 4548019 YP_899253.1 CDS ampG NC_008601.1 1753261 1754526 D major facilitator transporter 1753261..1754526 Francisella tularensis subsp. novicida U112 4548020 YP_899254.1 CDS sodB NC_008601.1 1754731 1755309 R iron/manganese superoxide dismutase family protein complement(1754731..1755309) Francisella tularensis subsp. novicida U112 4548021 YP_899255.1 CDS FTN_1643 NC_008601.1 1755445 1755774 D glutaredoxin-like protein 1755445..1755774 Francisella tularensis subsp. novicida U112 4548022 YP_899256.1 CDS FTN_1644 NC_008601.1 1755791 1758634 R hypothetical protein complement(1755791..1758634) Francisella tularensis subsp. novicida U112 4548023 YP_899257.1 CDS atpC NC_008601.1 1759707 1760144 R produces ATP from ADP in the presence of a proton gradient across the membrane; the epsilon subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit epsilon complement(1759707..1760144) Francisella tularensis subsp. novicida U112 4548024 YP_899258.1 CDS atpD NC_008601.1 1760157 1761533 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta complement(1760157..1761533) Francisella tularensis subsp. novicida U112 4548025 YP_899259.1 CDS atpG NC_008601.1 1761543 1762439 R produces ATP from ADP in the presence of a proton gradient across the membrane; the gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma complement(1761543..1762439) Francisella tularensis subsp. novicida U112 4548026 YP_899260.1 CDS atpA NC_008601.1 1762454 1763995 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha complement(1762454..1763995) Francisella tularensis subsp. novicida U112 4548027 YP_899261.1 CDS atpH NC_008601.1 1764014 1764538 R Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta complement(1764014..1764538) Francisella tularensis subsp. novicida U112 4548028 YP_899262.1 CDS atpF NC_008601.1 1764558 1765028 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B complement(1764558..1765028) Francisella tularensis subsp. novicida U112 4548029 YP_899263.1 CDS atpE NC_008601.1 1765074 1765379 R produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C complement(1765074..1765379) Francisella tularensis subsp. novicida U112 4548030 YP_899264.1 CDS atpB NC_008601.1 1765430 1766221 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A complement(1765430..1766221) Francisella tularensis subsp. novicida U112 4548031 YP_899265.1 CDS FTN_1653 NC_008601.1 1766274 1766705 R hypothetical protein complement(1766274..1766705) Francisella tularensis subsp. novicida U112 4548032 YP_899266.1 CDS FTN_1654 NC_008601.1 1766782 1768086 D major facilitator transporter 1766782..1768086 Francisella tularensis subsp. novicida U112 4548033 YP_899267.1 CDS rluC NC_008601.1 1768088 1769017 R ribosomal large subunit pseudouridine synthase C complement(1768088..1769017) Francisella tularensis subsp. novicida U112 4548034 YP_899268.1 CDS FTN_1656 NC_008601.1 1769010 1770077 R ATPase complement(1769010..1770077) Francisella tularensis subsp. novicida U112 4548035 YP_899269.1 CDS FTN_1657 NC_008601.1 1770080 1771378 R major facilitator transporter complement(1770080..1771378) Francisella tularensis subsp. novicida U112 4548036 YP_899270.1 CDS hisS NC_008601.1 1771385 1772650 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(1771385..1772650) Francisella tularensis subsp. novicida U112 4548037 YP_899271.1 CDS rbfA NC_008601.1 1772658 1773089 R ribosome-binding factor A complement(1772658..1773089) Francisella tularensis subsp. novicida U112 4548839 YP_899272.1 CDS infB NC_008601.1 1773092 1775632 R Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 complement(1773092..1775632) Francisella tularensis subsp. novicida U112 4548840 YP_899273.1 CDS nusA NC_008601.1 1775671 1777140 R modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA complement(1775671..1777140) Francisella tularensis subsp. novicida U112 4548841 YP_899274.1 CDS FTN_1662 NC_008601.1 1777158 1777610 R hypothetical protein complement(1777158..1777610) Francisella tularensis subsp. novicida U112 4548842 YP_899275.1 CDS hemE NC_008601.1 1777836 1778870 R catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase complement(1777836..1778870) Francisella tularensis subsp. novicida U112 4548844 YP_899276.1 CDS FTN_1665 NC_008601.1 1778924 1780432 R magnesium chelatase complement(1778924..1780432) Francisella tularensis subsp. novicida U112 4548845 YP_899277.1 CDS FTN_1666 NC_008601.1 1780434 1780628 R hypothetical protein complement(1780434..1780628) Francisella tularensis subsp. novicida U112 4548846 YP_899278.1 CDS nuoN NC_008601.1 1780704 1782155 R NADH dehydrogenase I subunit N complement(1780704..1782155) Francisella tularensis subsp. novicida U112 4548847 YP_899279.1 CDS nuoM NC_008601.1 1782171 1783760 R NADH dehydrogenase I subunit M complement(1782171..1783760) Francisella tularensis subsp. novicida U112 4548848 YP_899280.1 CDS nuoL NC_008601.1 1783786 1785795 R NADH dehydrogenase I subunit L complement(1783786..1785795) Francisella tularensis subsp. novicida U112 4548849 YP_899281.1 CDS nuoK NC_008601.1 1785805 1786122 R NADH dehydrogenase I subunit K complement(1785805..1786122) Francisella tularensis subsp. novicida U112 4548850 YP_899282.1 CDS nuoJ NC_008601.1 1786115 1786720 R NADH dehydrogenase I subunit J complement(1786115..1786720) Francisella tularensis subsp. novicida U112 4548851 YP_899283.1 CDS nuoI NC_008601.1 1786725 1787213 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I complement(1786725..1787213) Francisella tularensis subsp. novicida U112 4548852 YP_899284.1 CDS nuoH NC_008601.1 1787227 1788237 R NADH dehydrogenase I subunit H complement(1787227..1788237) Francisella tularensis subsp. novicida U112 4548853 YP_899285.1 CDS nuoG NC_008601.1 1788239 1790605 R Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit G complement(1788239..1790605) Francisella tularensis subsp. novicida U112 4548854 YP_899286.1 CDS nuoF NC_008601.1 1790623 1791897 R NADH dehydrogenase I subunit F complement(1790623..1791897) Francisella tularensis subsp. novicida U112 4548855 YP_899287.1 CDS nuoE NC_008601.1 1791904 1792392 R NADH dehydrogenase I subunit E complement(1791904..1792392) Francisella tularensis subsp. novicida U112 4548856 YP_899288.1 CDS nuoD NC_008601.1 1792402 1793655 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D complement(1792402..1793655) Francisella tularensis subsp. novicida U112 4548857 YP_899289.1 CDS nuoC NC_008601.1 1793677 1794321 R NADH dehydrogenase I subunit C complement(1793677..1794321) Francisella tularensis subsp. novicida U112 4548858 YP_899290.1 CDS nuoB NC_008601.1 1794324 1794800 R The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B complement(1794324..1794800) Francisella tularensis subsp. novicida U112 4548859 YP_899291.1 CDS nuoA NC_008601.1 1794791 1795189 R NADH dehydrogenase I subunit A complement(1794791..1795189) Francisella tularensis subsp. novicida U112 4548860 YP_899292.1 CDS fur NC_008601.1 1795398 1795820 D ferric uptake regulation protein 1795398..1795820 Francisella tularensis subsp. novicida U112 4548861 YP_899293.1 CDS frgA NC_008601.1 1796074 1797993 D siderophore biosynthesis protein 1796074..1797993 Francisella tularensis subsp. novicida U112 4548862 YP_899294.1 CDS FTN_1683 NC_008601.1 1798000 1799262 D drug:H+ antiporter-1 (DHA1) family protein 1798000..1799262 Francisella tularensis subsp. novicida U112 4548863 YP_899295.1 CDS FTN_1684 NC_008601.1 1799255 1800508 D diaminopimelate decarboxylase 1799255..1800508 Francisella tularensis subsp. novicida U112 4548864 YP_899296.1 CDS FTN_1685 NC_008601.1 1800523 1801713 D drug:H+ antiporter-1 (DHA1) family protein 1800523..1801713 Francisella tularensis subsp. novicida U112 4548865 YP_899297.1 CDS FTN_1686 NC_008601.1 1801799 1803328 D hypothetical protein 1801799..1803328 Francisella tularensis subsp. novicida U112 4548866 YP_899298.1 CDS FTN_1687 NC_008601.1 1803376 1804869 D GDSL-like lipolytic enzyme 1803376..1804869 Francisella tularensis subsp. novicida U112 4548867 YP_899299.1 CDS FTN_1688 NC_008601.1 1804885 1805292 R hypothetical protein complement(1804885..1805292) Francisella tularensis subsp. novicida U112 4548868 YP_899300.1 CDS gatB NC_008601.1 1805307 1806728 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B complement(1805307..1806728) Francisella tularensis subsp. novicida U112 4548869 YP_899301.1 CDS gatA NC_008601.1 1806731 1808176 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A complement(1806731..1808176) Francisella tularensis subsp. novicida U112 4548870 YP_899302.1 CDS gatC NC_008601.1 1808185 1808466 R Glu-tRNAGln amidotransferase C subunit complement(1808185..1808466) Francisella tularensis subsp. novicida U112 4548871 YP_899303.1 CDS FTN_1692 NC_008601.1 1808549 1809619 R membrane fusion protein complement(1808549..1809619) Francisella tularensis subsp. novicida U112 4548872 YP_899304.1 CDS FTN_1693 NC_008601.1 1809630 1811171 R ATP-binding cassette (ABC) superfamily protein complement(1809630..1811171) Francisella tularensis subsp. novicida U112 4548873 YP_899305.1 CDS purB NC_008601.1 1811327 1812625 R Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase complement(1811327..1812625) Francisella tularensis subsp. novicida U112 4548874 YP_899306.1 CDS FTN_1695 NC_008601.1 1812953 1813588 D hypothetical protein 1812953..1813588 Francisella tularensis subsp. novicida U112 4548875 YP_899307.1 CDS FTN_1696 NC_008601.1 1813595 1814377 D hypothetical protein 1813595..1814377 Francisella tularensis subsp. novicida U112 4548876 YP_899308.1 CDS FTN_1697 NC_008601.1 1814403 1815263 R galactose mutarotase complement(1814403..1815263) Francisella tularensis subsp. novicida U112 4548575 YP_899309.1 CDS FTN_1698 NC_008601.1 1815849 1816619 R Dam-replacing family protein complement(1815849..1816619) Francisella tularensis subsp. novicida U112 4548576 YP_899310.1 CDS purL NC_008601.1 1816647 1820534 R catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase complement(1816647..1820534) Francisella tularensis subsp. novicida U112 4548577 YP_899311.1 CDS purF NC_008601.1 1820534 1822024 R Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase complement(1820534..1822024) Francisella tularensis subsp. novicida U112 4548578 YP_899312.1 CDS FTN_1701 NC_008601.1 1822118 1823464 R glutamate decarboxylase complement(1822118..1823464) Francisella tularensis subsp. novicida U112 4548579 YP_899313.1 CDS FTN_1702 NC_008601.1 1823475 1824116 R phosphopantetheinyl transferase complement(1823475..1824116) Francisella tularensis subsp. novicida U112 4548580 YP_899314.1 CDS tolC NC_008601.1 1824125 1825654 R outer membrane protein tolC complement(1824125..1825654) Francisella tularensis subsp. novicida U112 4548581 YP_899315.1 CDS pcm NC_008601.1 1825663 1826283 R protein-L-isoaspartate O-methyltransferase complement(1825663..1826283) Francisella tularensis subsp. novicida U112 4548582 YP_899316.1 CDS FTN_1705 NC_008601.1 1826603 1827934 D U32 family peptidase 1826603..1827934 Francisella tularensis subsp. novicida U112 4548583 YP_899317.1 CDS FTN_1706 NC_008601.1 1827976 1829157 R drug:H+ antiporter-1 (DHA1) family protein complement(1827976..1829157) Francisella tularensis subsp. novicida U112 4548584 YP_899318.1 CDS nhaD NC_008601.1 1829332 1830759 D Na+/H+ antiporter 1829332..1830759 Francisella tularensis subsp. novicida U112 4548585 YP_899319.1 CDS FTN_1708 NC_008601.1 1830749 1832410 R ATP-binding cassette (ABC) superfamily protein complement(1830749..1832410) Francisella tularensis subsp. novicida U112 4548586 YP_899320.1 CDS FTN_1709 NC_008601.1 1832411 1834285 R amino acid transporter complement(1832411..1834285) Francisella tularensis subsp. novicida U112 4548587 YP_899321.1 CDS obgE NC_008601.1 1834292 1835296 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(1834292..1835296) Francisella tularensis subsp. novicida U112 4548588 YP_899322.1 CDS tyrP NC_008601.1 1835369 1836565 R tyrosine permease complement(1835369..1836565) Francisella tularensis subsp. novicida U112 4548589 YP_899323.1 CDS FTN_1712 NC_008601.1 1836693 1837148 D hypothetical protein 1836693..1837148 Francisella tularensis subsp. novicida U112 4548590 YP_899324.1 CDS FTN_1713 NC_008601.1 1837161 1837808 R hypothetical protein complement(1837161..1837808) Francisella tularensis subsp. novicida U112 4548591 YP_899325.1 CDS kdpE NC_008601.1 1837873 1838559 R two-component response regulator complement(1837873..1838559) Francisella tularensis subsp. novicida U112 4548592 YP_899326.1 CDS kdpD NC_008601.1 1838601 1841282 R two component regulator, sensor histidine kinase kdpD complement(1838601..1841282) Francisella tularensis subsp. novicida U112 4548593 YP_899327.1 CDS kdpC NC_008601.1 1841386 1841940 R potassium-transporting ATPase C chain complement(1841386..1841940) Francisella tularensis subsp. novicida U112 4548594 YP_899328.1 CDS kdpB NC_008601.1 1841957 1843996 R potassium-transporting ATPase B chain complement(1841957..1843996) Francisella tularensis subsp. novicida U112 4548595 YP_899329.1 CDS kdpA NC_008601.1 1844006 1845727 R catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions; potassium-transporting ATPase subunit A complement(1844006..1845727) Francisella tularensis subsp. novicida U112 4548596 YP_899330.1 CDS FTN_1719 NC_008601.1 1846030 1847178 R Catalyzes the reversible two-electron oxidation of formate to carbon dioxide. It allows the assimilation of carbon dioxide and provides energy for growth through oxidative phosphorylation coupled to the reduction of oxygen, nitrate, sulphate or fumarate; formate dehydrogenase complement(1846030..1847178) Francisella tularensis subsp. novicida U112 4548597 YP_899331.1 CDS aspC NC_008601.1 1852727 1853917 R aspartate aminotransferase complement(1852727..1853917) Francisella tularensis subsp. novicida U112 4548603 YP_899332.1 CDS FTN_1726 NC_008601.1 1853935 1855098 R pyridoxal-dependent decarboxylase complement(1853935..1855098) Francisella tularensis subsp. novicida U112 4548604 YP_899333.1 CDS dapD NC_008601.1 1855152 1855901 R catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase complement(1855152..1855901) Francisella tularensis subsp. novicida U112 4548605 YP_899334.1 CDS dapA NC_008601.1 1855925 1856812 R catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase complement(1855925..1856812) Francisella tularensis subsp. novicida U112 4548606 YP_899335.1 CDS dapB NC_008601.1 1856803 1857474 R dihydrodipicolinate reductase complement(1856803..1857474) Francisella tularensis subsp. novicida U112 4548607 YP_899336.1 CDS lysC NC_008601.1 1857486 1858841 R aspartate kinase III complement(1857486..1858841) Francisella tularensis subsp. novicida U112 4548608 YP_899337.1 CDS pip NC_008601.1 1859253 1860191 R proline iminopeptidase complement(1859253..1860191) Francisella tularensis subsp. novicida U112 4548668 YP_899338.1 CDS FTN_1732 NC_008601.1 1860267 1861013 R Mg-dependent DNase complement(1860267..1861013) Francisella tularensis subsp. novicida U112 4548669 YP_899339.1 CDS FTN_1733 NC_008601.1 1861014 1861637 R nicotinamide ribonucleoside (NR) uptake permease (PnuC) family protein complement(1861014..1861637) Francisella tularensis subsp. novicida U112 4548670 YP_899340.1 CDS FTN_1734 NC_008601.1 1861861 1862253 D hypothetical protein 1861861..1862253 Francisella tularensis subsp. novicida U112 4548671 YP_899341.1 CDS FTN_1735 NC_008601.1 1862274 1862684 D hypothetical protein 1862274..1862684 Francisella tularensis subsp. novicida U112 4548672 YP_899342.1 CDS FTN_1736 NC_008601.1 1862687 1863085 D hypothetical protein 1862687..1863085 Francisella tularensis subsp. novicida U112 4548673 YP_899343.1 CDS eriC NC_008601.1 1863156 1864574 D Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation; chloride channel protein 1863156..1864574 Francisella tularensis subsp. novicida U112 4548674 YP_899344.1 CDS FTN_1738 NC_008601.1 1864510 1866015 D metallocarboxypeptidase 1864510..1866015 Francisella tularensis subsp. novicida U112 4548675 YP_899345.1 CDS trpB NC_008601.1 1866821 1868011 D catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 1866821..1868011 Francisella tularensis subsp. novicida U112 4548676 YP_899346.1 CDS trpA NC_008601.1 1868014 1868820 D catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 1868014..1868820 Francisella tularensis subsp. novicida U112 4548677 YP_899347.1 CDS FTN_1741 NC_008601.1 1868875 1869228 R hypothetical protein complement(1868875..1869228) Francisella tularensis subsp. novicida U112 4548678 YP_899348.1 CDS pnuC NC_008601.1 1869318 1870028 R nicotinamide mononucleotide transporter complement(1869318..1870028) Francisella tularensis subsp. novicida U112 4548679 YP_899349.1 CDS clpB NC_008601.1 1870244 1872823 D chaperone clpB 1870244..1872823 Francisella tularensis subsp. novicida U112 4548680 YP_899350.1 CDS chiB NC_008601.1 1873074 1875266 D chitinase 1873074..1875266 Francisella tularensis subsp. novicida U112 4548681 YP_899351.1 CDS purT NC_008601.1 1875320 1876480 D non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 2 1875320..1876480 Francisella tularensis subsp. novicida U112 4548682 YP_899352.1 CDS FTN_1747 NC_008601.1 1877218 1877859 R hypothetical protein complement(1877218..1877859) Francisella tularensis subsp. novicida U112 4548684 YP_899353.1 CDS FTN_1748 NC_008601.1 1878089 1878412 D 4Fe-4S ferredoxin 1878089..1878412 Francisella tularensis subsp. novicida U112 4548685 YP_899354.1 CDS FTN_1749 NC_008601.1 1878575 1879327 D acyltransferase 1878575..1879327 Francisella tularensis subsp. novicida U112 4548686 YP_899355.1 CDS FTN_1750 NC_008601.1 1879341 1880081 D acyltransferase 1879341..1880081 Francisella tularensis subsp. novicida U112 4548687 YP_899356.1 CDS FTN_1751 NC_008601.1 1880087 1880806 R hypothetical protein complement(1880087..1880806) Francisella tularensis subsp. novicida U112 4548688 YP_899357.1 CDS nhaA NC_008601.1 1880871 1882022 R exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter complement(1880871..1882022) Francisella tularensis subsp. novicida U112 4548689 YP_899358.1 CDS FTN_1753 NC_008601.1 1882116 1883012 D Rieske (2Fe-2S) domain-containing protein 1882116..1883012 Francisella tularensis subsp. novicida U112 4548690 YP_899359.1 CDS FTN_1754 NC_008601.1 1883079 1883588 D cytochrome b561 family protein 1883079..1883588 Francisella tularensis subsp. novicida U112 4548691 YP_899360.1 CDS FTN_1755 NC_008601.1 1883615 1884874 D metabolite:H+ symporter (MHS) family protein 1883615..1884874 Francisella tularensis subsp. novicida U112 4548692 YP_899361.1 CDS bcp NC_008601.1 1885175 1885654 D bacterioferritin comigratory protein 1885175..1885654 Francisella tularensis subsp. novicida U112 4548693 YP_899362.1 CDS FTN_1757 NC_008601.1 1885732 1886715 R D-isomer specific 2-hydroxyacid dehydrogenase complement(1885732..1886715) Francisella tularensis subsp. novicida U112 4548694 YP_899363.1 CDS FTN_1758 NC_008601.1 1887821 1888441 D hypothetical protein 1887821..1888441 Francisella tularensis subsp. novicida U112 4548695 YP_899364.1 CDS FTN_1759 NC_008601.1 1888509 1888901 R hypothetical protein complement(1888509..1888901) Francisella tularensis subsp. novicida U112 4548696 YP_899365.1 CDS FTN_1760 NC_008601.1 1889010 1889999 D zinc-binding alcohol dehydrogenase 1889010..1889999 Francisella tularensis subsp. novicida U112 4548697 YP_899366.1 CDS FTN_1762 NC_008601.1 1890744 1892423 R ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; putative ABC transporter ATP-binding protein complement(1890744..1892423) Francisella tularensis subsp. novicida U112 4548699 YP_899367.1 CDS FTN_1763 NC_008601.1 1892635 1893855 D metabolite:H+ symporter (MHS) family protein 1892635..1893855 Francisella tularensis subsp. novicida U112 4548700 YP_899368.1 CDS FTN_1764 NC_008601.1 1893872 1894084 R hypothetical protein complement(1893872..1894084) Francisella tularensis subsp. novicida U112 4548701 YP_899369.1 CDS FTN_1765 NC_008601.1 1894130 1895101 D hypothetical protein 1894130..1895101 Francisella tularensis subsp. novicida U112 4548702 YP_899370.1 CDS FTN_1766 NC_008601.1 1895111 1896115 R drug/metabolite transporter (DMT) superfamily protein complement(1895111..1896115) Francisella tularensis subsp. novicida U112 4548703 YP_899371.1 CDS rbsK NC_008601.1 1896132 1897052 R ribokinase complement(1896132..1897052) Francisella tularensis subsp. novicida U112 4548704 YP_899372.1 CDS pepN NC_008601.1 1897170 1899746 R aminopeptidase N complement(1897170..1899746) Francisella tularensis subsp. novicida U112 4548745 YP_899373.1 CDS FTN_1769 NC_008601.1 1899948 1900376 D HSP20 family protein 1899948..1900376 Francisella tularensis subsp. novicida U112 4548746 YP_899374.1 CDS FTN_1770 NC_008601.1 1900373 1901734 R monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase complement(1900373..1901734) Francisella tularensis subsp. novicida U112 4548747 YP_899375.1 CDS FTN_1771 NC_008601.1 1901826 1902239 R hypothetical protein complement(1901826..1902239) Francisella tularensis subsp. novicida U112 4548748 YP_899376.1 CDS FTN_1772 NC_008601.1 1902244 1902933 R peptide methionine sulfoxide reductase complement(1902244..1902933) Francisella tularensis subsp. novicida U112 4548749 YP_899377.1 CDS FTN_1773 NC_008601.1 1903017 1903385 R hypothetical protein complement(1903017..1903385) Francisella tularensis subsp. novicida U112 4548750 YP_899378.1 CDS FTN_1774 NC_008601.1 1903378 1903719 R hypothetical protein complement(1903378..1903719) Francisella tularensis subsp. novicida U112 4548751 YP_899379.1 CDS FTN_1775 NC_008601.1 1903788 1904228 R hypothetical protein complement(1903788..1904228) Francisella tularensis subsp. novicida U112 4548752 YP_899380.1 CDS trpD NC_008601.1 1904290 1905303 R Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase complement(1904290..1905303) Francisella tularensis subsp. novicida U112 4548753 YP_899381.1 CDS trpG NC_008601.1 1905300 1905878 R anthranilate synthase component II complement(1905300..1905878) Francisella tularensis subsp. novicida U112 4548754 YP_899382.1 CDS trpE NC_008601.1 1905882 1907426 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(1905882..1907426) Francisella tularensis subsp. novicida U112 4548755 YP_899383.1 CDS trpR NC_008601.1 1907435 1907722 R trp operon repressor complement(1907435..1907722) Francisella tularensis subsp. novicida U112 4548756 YP_899384.1 CDS rng NC_008601.1 1908197 1909693 R ribonuclease G complement(1908197..1909693) Francisella tularensis subsp. novicida U112 4548759 FTN_0147 tRNA FTN_0147 NC_008601.1 160692 160766 R tRNA-Gln complement(160692..160766) Francisella tularensis subsp. novicida U112 4548157 FTN_0224 tRNA FTN_0224 NC_008601.1 248314 248389 R tRNA-Glu complement(248314..248389) Francisella tularensis subsp. novicida U112 4547824 FTN_0288 tRNA FTN_0288 NC_008601.1 295763 295839 D tRNA-Met 295763..295839 Francisella tularensis subsp. novicida U112 4548384 FTN_0366 tRNA FTN_0366 NC_008601.1 369054 369143 R tRNA-Ser complement(369054..369143) Francisella tularensis subsp. novicida U112 4548347 FTN_0469 tRNA FTN_0469 NC_008601.1 474850 474941 R tRNA-Ser complement(474850..474941) Francisella tularensis subsp. novicida U112 4548228 FTN_0470 tRNA FTN_0470 NC_008601.1 474969 475044 R tRNA-Val complement(474969..475044) Francisella tularensis subsp. novicida U112 4548229 FTN_0473 tRNA FTN_0473 NC_008601.1 477868 477944 R tRNA-Ile complement(477868..477944) Francisella tularensis subsp. novicida U112 4548232 FTN_0474 tRNA FTN_0474 NC_008601.1 477959 478034 R tRNA-Ala complement(477959..478034) Francisella tularensis subsp. novicida U112 4548233 FTN_0614 tRNA FTN_0614 NC_008601.1 646111 646186 R tRNA-Val complement(646111..646186) Francisella tularensis subsp. novicida U112 4548191 FTN_0650 tRNA FTN_0650 NC_008601.1 690857 690932 R tRNA-Lys complement(690857..690932) Francisella tularensis subsp. novicida U112 4547873 FTN_0726 tRNA FTN_0726 NC_008601.1 779775 779862 D tRNA-Ser 779775..779862 Francisella tularensis subsp. novicida U112 4547855 FTN_0796 tRNA FTN_0796 NC_008601.1 853311 853387 D tRNA-Val 853311..853387 Francisella tularensis subsp. novicida U112 4547335 FTN_1203 tRNA FTN_1203 NC_008601.1 1277239 1277321 D tRNA-Leu 1277239..1277321 Francisella tularensis subsp. novicida U112 4547624 FTN_1204 tRNA FTN_1204 NC_008601.1 1277328 1277403 D tRNA-His 1277328..1277403 Francisella tularensis subsp. novicida U112 4547382 FTN_1205 tRNA FTN_1205 NC_008601.1 1277431 1277507 D tRNA-Arg 1277431..1277507 Francisella tularensis subsp. novicida U112 4547383 FTN_1206 tRNA FTN_1206 NC_008601.1 1277516 1277592 D tRNA-Pro 1277516..1277592 Francisella tularensis subsp. novicida U112 4547384 FTN_1207 tRNA FTN_1207 NC_008601.1 1277610 1277685 D tRNA-Phe 1277610..1277685 Francisella tularensis subsp. novicida U112 4547385 FTN_1306 tRNA FTN_1306 NC_008601.1 1376136 1376211 D tRNA-Ala 1376136..1376211 Francisella tularensis subsp. novicida U112 4548433 FTN_1307 tRNA FTN_1307 NC_008601.1 1376226 1376302 D tRNA-Ile 1376226..1376302 Francisella tularensis subsp. novicida U112 4548434 FTN_1364 tRNA FTN_1364 NC_008601.1 1446894 1446982 D tRNA-Leu 1446894..1446982 Francisella tularensis subsp. novicida U112 4547921 FTN_1365 tRNA FTN_1365 NC_008601.1 1446988 1447061 D tRNA-Cys 1446988..1447061 Francisella tularensis subsp. novicida U112 4547922 FTN_1366 tRNA FTN_1366 NC_008601.1 1447077 1447151 D tRNA-Gly 1447077..1447151 Francisella tularensis subsp. novicida U112 4547923 FTN_1375 tRNA FTN_1375 NC_008601.1 1454404 1454479 R tRNA-Asn complement(1454404..1454479) Francisella tularensis subsp. novicida U112 4548282 FTN_1411 tRNA FTN_1411 NC_008601.1 1488584 1488670 D tRNA-Leu 1488584..1488670 Francisella tularensis subsp. novicida U112 4547786 FTN_1473 tRNA FTN_1473 NC_008601.1 1561358 1561434 R tRNA-Met complement(1561358..1561434) Francisella tularensis subsp. novicida U112 4548568 FTN_1497 tRNA FTN_1497 NC_008601.1 1593024 1593100 R tRNA-Arg complement(1593024..1593100) Francisella tularensis subsp. novicida U112 4548535 FTN_1498 tRNA FTN_1498 NC_008601.1 1593115 1593189 R tRNA-Gly complement(1593115..1593189) Francisella tularensis subsp. novicida U112 4547338 FTN_1541 tRNA FTN_1541 NC_008601.1 1639536 1639611 R tRNA-Arg complement(1639536..1639611) Francisella tularensis subsp. novicida U112 4548903 FTN_1575 tRNA FTN_1575 NC_008601.1 1675539 1675614 D tRNA-Trp 1675539..1675614 Francisella tularensis subsp. novicida U112 4548918 FTN_1577 tRNA FTN_1577 NC_008601.1 1676863 1676938 D tRNA-Thr 1676863..1676938 Francisella tularensis subsp. novicida U112 4548920 FTN_1578 tRNA FTN_1578 NC_008601.1 1676967 1677040 D tRNA-Gly 1676967..1677040 Francisella tularensis subsp. novicida U112 4548921 FTN_1579 tRNA FTN_1579 NC_008601.1 1677042 1677126 D tRNA-Tyr 1677042..1677126 Francisella tularensis subsp. novicida U112 4548922 FTN_1629 tRNA FTN_1629 NC_008601.1 1740867 1740952 D tRNA-Leu 1740867..1740952 Francisella tularensis subsp. novicida U112 4548008 FTN_1663 tRNA FTN_1663 NC_008601.1 1777686 1777762 D tRNA-Met 1777686..1777762 Francisella tularensis subsp. novicida U112 4548843 FTN_1722 tRNA FTN_1722 NC_008601.1 1850608 1850683 D tRNA-Ala 1850608..1850683 Francisella tularensis subsp. novicida U112 4548600 FTN_1723 tRNA FTN_1723 NC_008601.1 1850698 1850774 D tRNA-Ile 1850698..1850774 Francisella tularensis subsp. novicida U112 4548601 FTN_1780 tRNA FTN_1780 NC_008601.1 1907978 1908054 D tRNA-Asp 1907978..1908054 Francisella tularensis subsp. novicida U112 4548757 FTN_1781 tRNA FTN_1781 NC_008601.1 1908059 1908134 D tRNA-Thr 1908059..1908134 Francisella tularensis subsp. novicida U112 4548758 FTN_0472 rRNA FTN_0472 NC_008601.1 476249 477772 D 16S ribosomal RNA 476249..477772 Francisella tularensis subsp. novicida U112 4548231 FTN_0475 rRNA FTN_0475 NC_008601.1 478108 480969 D 23S ribosomal RNA 478108..480969 Francisella tularensis subsp. novicida U112 4548234 FTN_0476 rRNA FTN_0476 NC_008601.1 481018 481134 D 5S ribosomal RNA 481018..481134 Francisella tularensis subsp. novicida U112 4548235 FTN_0501 rRNA FTN_0501 NC_008601.1 509999 510121 D 5S ribosomal RNA 509999..510121 Francisella tularensis subsp. novicida U112 4547668 FTN_1304 rRNA FTN_1304 NC_008601.1 1373036 1373150 R 5S ribosomal RNA complement(1373036..1373150) Francisella tularensis subsp. novicida U112 4548431 FTN_1305 rRNA FTN_1305 NC_008601.1 1373201 1376062 R 23S ribosomal RNA complement(1373201..1376062) Francisella tularensis subsp. novicida U112 4548432 FTN_1308 rRNA FTN_1308 NC_008601.1 1376398 1377921 R 16S ribosomal RNA complement(1376398..1377921) Francisella tularensis subsp. novicida U112 4548435 FTN_1720 rRNA FTN_1720 NC_008601.1 1847508 1847624 R 5S ribosomal RNA complement(1847508..1847624) Francisella tularensis subsp. novicida U112 4548598 FTN_1721 rRNA FTN_1721 NC_008601.1 1847673 1850534 R 23S ribosomal RNA complement(1847673..1850534) Francisella tularensis subsp. novicida U112 4548599 FTN_1724 rRNA FTN_1724 NC_008601.1 1850870 1852393 R 16S ribosomal RNA complement(1850870..1852393) Francisella tularensis subsp. novicida U112 4548602